LOCUS       DAFEIE010000001       155375 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFEIE010000001
VERSION     DAFEIE010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 155375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 155375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..155375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.001"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(3..2189)
                     /locus_tag="LP345_000001"
     CDS             complement(3..2189)
                     /locus_tag="LP345_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL1758824.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNISVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            2407..3090
                     /locus_tag="LP345_000002"
     CDS             2407..3090
                     /locus_tag="LP345_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBL1758825.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(3171..3890)
                     /locus_tag="LP345_000003"
     CDS             complement(3171..3890)
                     /locus_tag="LP345_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL1758826.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4202..4408)
                     /locus_tag="LP345_000004"
     CDS             complement(4202..4408)
                     /locus_tag="LP345_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758827.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            4653..5255
                     /locus_tag="LP345_000005"
     CDS             4653..5255
                     /locus_tag="LP345_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL1758828.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            5396..6676
                     /locus_tag="LP345_000006"
     CDS             5396..6676
                     /locus_tag="LP345_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL1758829.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            6689..7417
                     /locus_tag="LP345_000007"
     CDS             6689..7417
                     /locus_tag="LP345_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1758830.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(7486..9009)
                     /locus_tag="LP345_000008"
     CDS             complement(7486..9009)
                     /locus_tag="LP345_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL1758831.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            9261..10442
                     /locus_tag="LP345_000009"
     CDS             9261..10442
                     /locus_tag="LP345_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1758832.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(10502..12130)
                     /gene="treC"
                     /locus_tag="LP345_000010"
     CDS             complement(10502..12130)
                     /gene="treC"
                     /locus_tag="LP345_000010"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBL1758833.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGAKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12581..15292)
                     /locus_tag="LP345_000011"
     CDS             complement(12581..15292)
                     /locus_tag="LP345_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1758834.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGTIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(15302..16003)
                     /locus_tag="LP345_000012"
     CDS             complement(15302..16003)
                     /locus_tag="LP345_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1758835.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            16189..16788
                     /locus_tag="LP345_000013"
     CDS             16189..16788
                     /locus_tag="LP345_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1758836.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            16869..17882
                     /locus_tag="LP345_000014"
     CDS             16869..17882
                     /locus_tag="LP345_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL1758837.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            17990..18907
                     /gene="rbsK"
                     /locus_tag="LP345_000015"
     CDS             17990..18907
                     /gene="rbsK"
                     /locus_tag="LP345_000015"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBL1758838.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            18935..19329
                     /gene="rbsD"
                     /locus_tag="LP345_000016"
                     /pseudo
     CDS             18935..19329
                     /gene="rbsD"
                     /locus_tag="LP345_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
     gene            19329..20702
                     /locus_tag="LP345_000017"
     CDS             19329..20702
                     /locus_tag="LP345_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1758839.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            21059..23203
                     /locus_tag="LP345_000018"
     CDS             21059..23203
                     /locus_tag="LP345_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL1758840.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(23255..24295)
                     /locus_tag="LP345_000019"
     CDS             complement(23255..24295)
                     /locus_tag="LP345_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL1758841.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(24572..26374)
                     /locus_tag="LP345_000020"
     CDS             complement(24572..26374)
                     /locus_tag="LP345_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1758842.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(26388..27140)
                     /locus_tag="LP345_000021"
     CDS             complement(26388..27140)
                     /locus_tag="LP345_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1758843.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(27149..27511)
                     /locus_tag="LP345_000022"
     CDS             complement(27149..27511)
                     /locus_tag="LP345_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1758844.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(27687..28559)
                     /locus_tag="LP345_000023"
     CDS             complement(27687..28559)
                     /locus_tag="LP345_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL1758845.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(28585..29097)
                     /locus_tag="LP345_000024"
     CDS             complement(28585..29097)
                     /locus_tag="LP345_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBL1758846.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            complement(29235..30026)
                     /locus_tag="LP345_000025"
     CDS             complement(29235..30026)
                     /locus_tag="LP345_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBL1758847.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(30081..30689)
                     /locus_tag="LP345_000026"
     CDS             complement(30081..30689)
                     /locus_tag="LP345_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBL1758848.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLVWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(30682..30999)
                     /locus_tag="LP345_000027"
     CDS             complement(30682..30999)
                     /locus_tag="LP345_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1758849.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(31155..31883)
                     /locus_tag="LP345_000028"
     CDS             complement(31155..31883)
                     /locus_tag="LP345_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBL1758850.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            32042..32923
                     /locus_tag="LP345_000029"
     CDS             32042..32923
                     /locus_tag="LP345_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1758851.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(33160..34203)
                     /locus_tag="LP345_000030"
     CDS             complement(33160..34203)
                     /locus_tag="LP345_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1758852.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(34206..34874)
                     /locus_tag="LP345_000031"
     CDS             complement(34206..34874)
                     /locus_tag="LP345_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1758853.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            35016..37352
                     /locus_tag="LP345_000032"
     CDS             35016..37352
                     /locus_tag="LP345_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1758854.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(37467..37778)
                     /locus_tag="LP345_000033"
     CDS             complement(37467..37778)
                     /locus_tag="LP345_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758855.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            37959..39434
                     /locus_tag="LP345_000034"
     CDS             37959..39434
                     /locus_tag="LP345_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBL1758856.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPTMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            39481..40065
                     /locus_tag="LP345_000035"
     CDS             39481..40065
                     /locus_tag="LP345_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBL1758857.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            40067..40486
                     /locus_tag="LP345_000036"
     CDS             40067..40486
                     /locus_tag="LP345_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBL1758858.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(40767..41051)
                     /locus_tag="LP345_000037"
     CDS             complement(40767..41051)
                     /locus_tag="LP345_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBL1758859.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(41403..42113)
                     /locus_tag="LP345_000038"
     CDS             complement(41403..42113)
                     /locus_tag="LP345_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBL1758860.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(42110..43582)
                     /locus_tag="LP345_000039"
     CDS             complement(42110..43582)
                     /locus_tag="LP345_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL1758861.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            43720..44193
                     /locus_tag="LP345_000040"
     CDS             43720..44193
                     /locus_tag="LP345_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1758862.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(44346..44897)
                     /locus_tag="LP345_000041"
     CDS             complement(44346..44897)
                     /locus_tag="LP345_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1758863.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            45002..45532
                     /locus_tag="LP345_000042"
     CDS             45002..45532
                     /locus_tag="LP345_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBL1758864.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(46015..46458)
                     /locus_tag="LP345_000043"
     CDS             complement(46015..46458)
                     /locus_tag="LP345_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1758865.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(46474..47634)
                     /locus_tag="LP345_000044"
     CDS             complement(46474..47634)
                     /locus_tag="LP345_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1758866.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            48141..49841
                     /locus_tag="LP345_000045"
     CDS             48141..49841
                     /locus_tag="LP345_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758867.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(49943..50776)
                     /locus_tag="LP345_000046"
     CDS             complement(49943..50776)
                     /locus_tag="LP345_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBL1758868.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(51080..53245)
                     /locus_tag="LP345_000047"
     CDS             complement(51080..53245)
                     /locus_tag="LP345_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1758869.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            53505..55799
                     /locus_tag="LP345_000048"
     CDS             53505..55799
                     /locus_tag="LP345_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL1758870.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFKLLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            55792..56457
                     /gene="pgmB"
                     /locus_tag="LP345_000049"
     CDS             55792..56457
                     /gene="pgmB"
                     /locus_tag="LP345_000049"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL1758871.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFTKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            56450..57457
                     /locus_tag="LP345_000050"
     CDS             56450..57457
                     /locus_tag="LP345_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL1758872.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            57479..58498
                     /locus_tag="LP345_000051"
     CDS             57479..58498
                     /locus_tag="LP345_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1758873.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(58779..60146)
                     /gene="nhaC"
                     /locus_tag="LP345_000052"
     CDS             complement(58779..60146)
                     /gene="nhaC"
                     /locus_tag="LP345_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL1758874.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(60255..61676)
                     /locus_tag="LP345_000053"
     CDS             complement(60255..61676)
                     /locus_tag="LP345_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1758875.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(61919..63796)
                     /gene="tdc"
                     /locus_tag="LP345_000054"
     CDS             complement(61919..63796)
                     /gene="tdc"
                     /locus_tag="LP345_000054"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL1758876.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(64087..65343)
                     /locus_tag="LP345_000055"
     CDS             complement(64087..65343)
                     /locus_tag="LP345_000055"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBL1758877.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(65455..65660)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            65923..67224
                     /locus_tag="LP345_000056"
     CDS             65923..67224
                     /locus_tag="LP345_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL1758878.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(67293..67892)
                     /locus_tag="LP345_000057"
     CDS             complement(67293..67892)
                     /locus_tag="LP345_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1758879.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            68146..69027
                     /locus_tag="LP345_000058"
     CDS             68146..69027
                     /locus_tag="LP345_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1758880.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            69040..70650
                     /locus_tag="LP345_000059"
     CDS             69040..70650
                     /locus_tag="LP345_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBL1758881.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(70727..71386)
                     /locus_tag="LP345_000060"
     CDS             complement(70727..71386)
                     /locus_tag="LP345_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL1758882.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(71669..72334)
                     /locus_tag="LP345_000061"
     CDS             complement(71669..72334)
                     /locus_tag="LP345_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBL1758883.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(72481..73086)
                     /gene="dhaL"
                     /locus_tag="LP345_000062"
     CDS             complement(72481..73086)
                     /gene="dhaL"
                     /locus_tag="LP345_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBL1758884.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(73114..74124)
                     /gene="dhaK"
                     /locus_tag="LP345_000063"
     CDS             complement(73114..74124)
                     /gene="dhaK"
                     /locus_tag="LP345_000063"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBL1758885.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(74099..74545)
                     /gene="dhaM"
                     /locus_tag="LP345_000064"
     CDS             complement(74099..74545)
                     /gene="dhaM"
                     /locus_tag="LP345_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBL1758886.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            74648..74968
                     /locus_tag="LP345_000065"
     CDS             74648..74968
                     /locus_tag="LP345_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBL1758887.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(75080..75949)
                     /locus_tag="LP345_000066"
     CDS             complement(75080..75949)
                     /locus_tag="LP345_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1758888.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(76045..77349)
                     /locus_tag="LP345_000067"
     CDS             complement(76045..77349)
                     /locus_tag="LP345_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1758889.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(77346..77855)
                     /locus_tag="LP345_000068"
     CDS             complement(77346..77855)
                     /locus_tag="LP345_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758890.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(78030..80165)
                     /locus_tag="LP345_000069"
     CDS             complement(78030..80165)
                     /locus_tag="LP345_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1758891.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(80248..81903)
                     /locus_tag="LP345_000070"
     CDS             complement(80248..81903)
                     /locus_tag="LP345_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1758892.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(81905..82219)
                     /locus_tag="LP345_000071"
     CDS             complement(81905..82219)
                     /locus_tag="LP345_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL1758893.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            82389..82649
                     /locus_tag="LP345_000072"
     CDS             82389..82649
                     /locus_tag="LP345_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBL1758894.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            82663..82977
                     /locus_tag="LP345_000073"
     CDS             82663..82977
                     /locus_tag="LP345_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBL1758895.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(83707..84261)
                     /locus_tag="LP345_000074"
     CDS             complement(83707..84261)
                     /locus_tag="LP345_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBL1758896.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(84387..86316)
                     /locus_tag="LP345_000075"
                     /pseudo
     CDS             complement(84387..86316)
                     /locus_tag="LP345_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(86622..87338)
                     /locus_tag="LP345_000076"
     CDS             complement(86622..87338)
                     /locus_tag="LP345_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL1758897.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(87339..89162)
                     /gene="glpO"
                     /locus_tag="LP345_000077"
     CDS             complement(87339..89162)
                     /gene="glpO"
                     /locus_tag="LP345_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBL1758898.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(89176..90672)
                     /gene="glpK"
                     /locus_tag="LP345_000078"
     CDS             complement(89176..90672)
                     /gene="glpK"
                     /locus_tag="LP345_000078"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBL1758899.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(90808..92268)
                     /locus_tag="LP345_000079"
     CDS             complement(90808..92268)
                     /locus_tag="LP345_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1758900.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(92258..93553)
                     /locus_tag="LP345_000080"
     CDS             complement(92258..93553)
                     /locus_tag="LP345_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1758901.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(93885..94562)
                     /locus_tag="LP345_000081"
     CDS             complement(93885..94562)
                     /locus_tag="LP345_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBL1758902.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(94592..95683)
                     /locus_tag="LP345_000082"
     CDS             complement(94592..95683)
                     /locus_tag="LP345_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBL1758903.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(95784..96218)
                     /locus_tag="LP345_000083"
     CDS             complement(95784..96218)
                     /locus_tag="LP345_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1758904.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(96802..98259)
                     /gene="ascB"
                     /locus_tag="LP345_000084"
     CDS             complement(96802..98259)
                     /gene="ascB"
                     /locus_tag="LP345_000084"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL1758905.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(98256..100151)
                     /locus_tag="LP345_000085"
     CDS             complement(98256..100151)
                     /locus_tag="LP345_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1758906.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(100209..101984)
                     /locus_tag="LP345_000086"
     CDS             complement(100209..101984)
                     /locus_tag="LP345_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL1758907.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(102034..103530)
                     /locus_tag="LP345_000087"
     CDS             complement(102034..103530)
                     /locus_tag="LP345_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1758908.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(103724..105346)
                     /locus_tag="LP345_000088"
     CDS             complement(103724..105346)
                     /locus_tag="LP345_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL1758909.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(105674..106987)
                     /locus_tag="LP345_000089"
     CDS             complement(105674..106987)
                     /locus_tag="LP345_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL1758910.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(107232..107456)
                     /locus_tag="LP345_000090"
     CDS             complement(107232..107456)
                     /locus_tag="LP345_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758911.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(107476..107898)
                     /locus_tag="LP345_000091"
     CDS             complement(107476..107898)
                     /locus_tag="LP345_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBL1758912.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(108041..108751)
                     /locus_tag="LP345_000092"
     CDS             complement(108041..108751)
                     /locus_tag="LP345_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758913.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(108769..109266)
                     /locus_tag="LP345_000093"
     CDS             complement(108769..109266)
                     /locus_tag="LP345_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1758914.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(109303..109755)
                     /locus_tag="LP345_000094"
     CDS             complement(109303..109755)
                     /locus_tag="LP345_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1758915.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(109890..110495)
                     /locus_tag="LP345_000095"
     CDS             complement(109890..110495)
                     /locus_tag="LP345_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL1758916.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(110945..111565)
                     /locus_tag="LP345_000096"
     CDS             complement(110945..111565)
                     /locus_tag="LP345_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL1758917.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(111567..112436)
                     /locus_tag="LP345_000097"
     CDS             complement(111567..112436)
                     /locus_tag="LP345_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBL1758918.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(112459..112866)
                     /locus_tag="LP345_000098"
     CDS             complement(112459..112866)
                     /locus_tag="LP345_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL1758919.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(112885..114174)
                     /locus_tag="LP345_000099"
     CDS             complement(112885..114174)
                     /locus_tag="LP345_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1758920.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGDFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(114201..114503)
                     /locus_tag="LP345_000100"
     CDS             complement(114201..114503)
                     /locus_tag="LP345_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1758921.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(114528..116621)
                     /locus_tag="LP345_000101"
     CDS             complement(114528..116621)
                     /locus_tag="LP345_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1758922.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(117110..117874)
                     /locus_tag="LP345_000102"
     CDS             complement(117110..117874)
                     /locus_tag="LP345_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBL1758923.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(117985..118854)
                     /gene="mdcB"
                     /locus_tag="LP345_000103"
     CDS             complement(117985..118854)
                     /gene="mdcB"
                     /locus_tag="LP345_000103"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBL1758924.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(118879..119955)
                     /locus_tag="LP345_000104"
     CDS             complement(118879..119955)
                     /locus_tag="LP345_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBL1758925.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(119979..120572)
                     /locus_tag="LP345_000105"
     CDS             complement(119979..120572)
                     /locus_tag="LP345_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBL1758926.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(120576..122252)
                     /gene="mdcD"
                     /locus_tag="LP345_000106"
     CDS             complement(120576..122252)
                     /gene="mdcD"
                     /locus_tag="LP345_000106"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBL1758927.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(122242..122541)
                     /locus_tag="LP345_000107"
     CDS             complement(122242..122541)
                     /locus_tag="LP345_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBL1758928.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(122643..124289)
                     /gene="mdcA"
                     /locus_tag="LP345_000108"
     CDS             complement(122643..124289)
                     /gene="mdcA"
                     /locus_tag="LP345_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HBL1758929.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(124296..125207)
                     /locus_tag="LP345_000109"
     CDS             complement(124296..125207)
                     /locus_tag="LP345_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL1758930.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            125327..126184
                     /locus_tag="LP345_000110"
     CDS             125327..126184
                     /locus_tag="LP345_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1758931.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(126371..126733)
                     /locus_tag="LP345_000111"
     CDS             complement(126371..126733)
                     /locus_tag="LP345_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBL1758932.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            127079..128518
                     /locus_tag="LP345_000112"
     CDS             127079..128518
                     /locus_tag="LP345_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1758933.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(128525..131071)
                     /locus_tag="LP345_000113"
     CDS             complement(128525..131071)
                     /locus_tag="LP345_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBL1758934.1"
                     /translation="MVQIDGRRCIVNYQTSTEGLSQEERQKRLTDQGYNEIKARQQTK
                     RWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEESL
                     NGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVEES
                     ILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKINQ
                     ALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIALVV
                     SMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNEMT
                     VVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKIEA
                     KIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARKGQ
                     RVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKMIT
                     GDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLRIV
                     KALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTIAK
                     AVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTITL
                     SYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQSLQ
                     QTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPVGQ
                     QLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(131190..132521)
                     /locus_tag="LP345_000114"
     CDS             complement(131190..132521)
                     /locus_tag="LP345_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1758935.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(132487..133965)
                     /locus_tag="LP345_000115"
     CDS             complement(132487..133965)
                     /locus_tag="LP345_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1758936.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(134270..136105)
                     /gene="tdc"
                     /locus_tag="LP345_000116"
     CDS             complement(134270..136105)
                     /gene="tdc"
                     /locus_tag="LP345_000116"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL1758937.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            136575..138002
                     /locus_tag="LP345_000117"
     CDS             136575..138002
                     /locus_tag="LP345_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1758938.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(138094..138459)
                     /locus_tag="LP345_000118"
     CDS             complement(138094..138459)
                     /locus_tag="LP345_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL1758939.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(138456..138821)
                     /locus_tag="LP345_000119"
     CDS             complement(138456..138821)
                     /locus_tag="LP345_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL1758940.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(139013..139261)
                     /locus_tag="LP345_000120"
     CDS             complement(139013..139261)
                     /locus_tag="LP345_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758941.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            139260..139388
                     /locus_tag="LP345_000121"
     CDS             139260..139388
                     /locus_tag="LP345_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBL1758942.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            139445..141139
                     /locus_tag="LP345_000122"
     CDS             139445..141139
                     /locus_tag="LP345_000122"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBL1758943.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            141143..141262
                     /locus_tag="LP345_000123"
                     /pseudo
     CDS             141143..141262
                     /locus_tag="LP345_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            141239..141535
                     /locus_tag="LP345_000124"
     CDS             141239..141535
                     /locus_tag="LP345_000124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758944.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            141913..143046
                     /locus_tag="LP345_000125"
     CDS             141913..143046
                     /locus_tag="LP345_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBL1758945.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            143077..143397
                     /locus_tag="LP345_000126"
     CDS             143077..143397
                     /locus_tag="LP345_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBL1758946.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(143426..143890)
                     /locus_tag="LP345_000127"
     CDS             complement(143426..143890)
                     /locus_tag="LP345_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1758947.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(144022..145276)
                     /locus_tag="LP345_000128"
                     /pseudo
     CDS             complement(144022..145276)
                     /locus_tag="LP345_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(145305..145622)
                     /locus_tag="LP345_000129"
     CDS             complement(145305..145622)
                     /locus_tag="LP345_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL1758948.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(145648..145968)
                     /locus_tag="LP345_000130"
     CDS             complement(145648..145968)
                     /locus_tag="LP345_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1758949.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(146432..147847)
                     /locus_tag="LP345_000131"
     CDS             complement(146432..147847)
                     /locus_tag="LP345_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1758950.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(147864..149180)
                     /locus_tag="LP345_000132"
     CDS             complement(147864..149180)
                     /locus_tag="LP345_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1758951.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(149330..150028)
                     /locus_tag="LP345_000133"
     CDS             complement(149330..150028)
                     /locus_tag="LP345_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBL1758952.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(150317..151273)
                     /locus_tag="LP345_000134"
     CDS             complement(150317..151273)
                     /locus_tag="LP345_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1758953.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(151386..152219)
                     /gene="msrA"
                     /locus_tag="LP345_000135"
     CDS             complement(151386..152219)
                     /gene="msrA"
                     /locus_tag="LP345_000135"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL1758954.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(152394..154022)
                     /locus_tag="LP345_000136"
     CDS             complement(152394..154022)
                     /locus_tag="LP345_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758955.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIRLVSKGFKNADFIAI
                     FKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNNDL
                     TTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAKLL
                     QFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFNQK
                     IISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNLPY
                     KTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGVAD
                     IKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(154009..155343)
                     /locus_tag="LP345_000137"
     CDS             complement(154009..155343)
                     /locus_tag="LP345_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758956.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT        45871 a        32099 c        26970 g        50435 t
ORIGIN      
        1 tatcactttc cttttttcac acgactcccg gtttctttga taaatctcga tactttcaat
       61 tttcttgaat ttttcatttg aggtacacat agatacagac gatttcttgc tctagtcatc
      121 gcaacataaa atagtcttcg ttcttcttct atcgtcgtta ctggttctgc ttttatttca
      181 ttaaagtcga ttactttctt ttctgtcgct ccgttataag gcaaacttcc ttcgttacaa
      241 ccaatcaaaa agacatttcg gtaactaaga cctttacttt tgtgaatgct ctggatacat
      301 agtgcatcaa gttttccttg tctgtaagca atcaagcggg tttttaattc tttagctgtc
      361 gcttgggttt cttgcgataa ggcttggagt cttctgaaag tagcatgctg ctttacttct
      421 tctcgtatcc attcttgatc actctggtcg atttccttag ctatacgtgg cagatgaaga
      481 tagctttgaa caagcgaata gatttcttga tgctggtctg ttttacgcaa cgcttcctca
      541 aactctcgga tttctgcaga tttcgatttt aaattggggc ttatcgacaa aatataatct
      601 gcaacggata tattttgata tttaggagaa aagtattgat cgcattcact ttttttcagg
      661 tagcagtctg ccatcagctg ccggagcaat tgctggtagg cctgattttt cttttgcaga
      721 ttcagtgctg tttgccaatg aacaattttt tgatagaaat gttggaaaga cttgatacca
      781 aagatacctt catatggact atctgcttcc agtacaaaag gaatattcgt tttcagcaga
      841 gattggacaa gctgctgcgt ttgtgaagct gatcggtata atatgattga ttccttatat
      901 ttcccatttt tttgaataaa tgtctgaatt tgtttgatta gccactgact ttctgcttta
      961 gtatcagaaa acaaataggc ttccataaca cctgcttctt tttgtgctgg aatcatcgcc
     1021 tttggtatcc gatcattttt attatagctg atcaatctat ttgctccttg gacaatagct
     1081 gcccgagaac gataattagt taataagaaa agagttttgg taggatattc tttttcaaag
     1141 ttcttgatgt atgctggctc tgatcctctg aatccataga tactctgatc atcatctcca
     1201 acaacaatca acttgatcct gttttccttt gtcatccgtt tcacgatttc ccattgaagt
     1261 ggattagtat cttgaaattc atcaatgaat agataatcat atttttggcc gatataatgc
     1321 tggatctcct cattctccaa agcgcttttc agattttgga gtacatcatt gaactctagc
     1381 aattgctggc ttcttttttg ttcttggagt tccgtgagca atccatacag tcgttctgat
     1441 atcggctgtc gtgcattctt atcaatggaa tcatattttt ctttaactaa ctgaaccatt
     1501 tcttctactg aaaggttcat attctgccaa tagtctaacc gagaagcaat cgttttttct
     1561 ccatattgat caaatatata aagattatat ttacgtatca gctgttgcaa aacagcattc
     1621 actttttgtg cagtatcctt tgaaaagtct ccttgtattc cttgcattgc tacttcagga
     1681 aattttcgac aaatttcatt gtatatccta aaaaagatac tatggaatgt tccgatatgg
     1741 acagcggttt ttctctggct gaaattatct actcgttttt ttagttcatt tgcagcgttc
     1801 cttgtaaaag tgatcattag tatgcgttct tcgtctactt gtttttgcgt catcagataa
     1861 acagcttttg cacagattgt ttgcgttttg ccgctcccag ctcctgctat gattcgaaga
     1921 tgtttcttca tatcatatgt gatagctgct ttttgttctt gattgaagcg attataggaa
     1981 cgtttctcca tcattttaaa gaaagagctg tttccttcac tttcttttac ttgtacttct
     2041 tcctcaataa gtccgggtgc ttcgccataa gccgcttcat aggtagcaat gatttcttct
     2101 tgtagccgaa agacttgttg aagcttttta tacttgttct cccagcgttt caattctttt
     2161 tgtaatcgga gaatttcttt ttcattcaac tgattgattt ccttcccatc tttcttcttt
     2221 gaatttgttt atttcaagtt ggttatttaa agtttcgttg tctatttttt ctttatacta
     2281 acagaccttt ctaaaaatga aaatgggaag cgatatgatt ttagttttct gaaaattttt
     2341 cctttttttc aatcgtttat gctaagataa ggaagacaaa aatattcata aaaggtgatg
     2401 aaaaaaatgc agacttcctt tcacgagggg cgtacaatag gacttttgct gacatttatc
     2461 ggaggagcca tggacagtta tacttatatc caatatggtg cttttgcctc tgctcaaact
     2521 ggcaatatca ttctatcgat catccaagca tttgacggag aatggctaag tgttggtaaa
     2581 aaagtattgt ctaccctttt ctttttctta gggattcttc taacaaagta tctaattgat
     2641 tattttagaa aaaaagaaaa acatttctgg cgcttgtttg ttctatatta tgaagcagtg
     2701 atttttttct ttgttagttt gacacccgtc catgagcatc ccgcattagt aacgattttg
     2761 attgctttta ctgcatcgat ccagtgggta gcttttgata aaatcaacgg gcgtgcctac
     2821 actaatttat ttacaactgg aaatttaaaa ggggtagcaa cgaacttata tgattattgt
     2881 atttctaaag aaaaagcaga ttttgatcga tttttccact atctaagtgt cgttcttgcc
     2941 tttatcgcag gagctattgt ccttgttttc tgtcatcatc tgtttggcgc ccattcgatt
     3001 ttgatcgttt ccattttatt tttgatcatg gccctcactc agacatttca tttatggcaa
     3061 ttttatcata cgaatcggtt cactatttga tctcaatgaa tcaaaaaaac taagcaagat
     3121 gctgctcaca gagaaatatc tgcgagtgag caatttgctt agtttttata ttatttagtt
     3181 gtaaagattc cctttgcttt cgggttattt gtagtgtagc ggatcgactg ggcatctgcc
     3241 tcttctgtca ttttctttgc ccgcatcttg atttcttgta cgatttgttc tccacatgcc
     3301 ggatcggcta cgaaatcata tttgtcccca tcgatcacta ttttgggaca tatatcaaac
     3361 tgttcatacc actcttcgta tcgtcgattg agttctttat agtaggaata gagttcagga
     3421 tcttgttcta gctgttcata ttcccggcct ctttttttga ttctcgctaa catagtttca
     3481 aaggatacac gaatataaac cagtagatct ggtttctttt gtggcgaaat ttcttctaac
     3541 tccttcagca tcgtttctaa aagaccttca tactgcttta cttctacttc agaaacacgc
     3601 cctaaatctg cattcaaatg aaacagcata ctatcttcgt agatggagcg gtctagtacg
     3661 ttgtcatcat ggctgaaagc atctttgatt gccaaaaagc gtttgttcaa aaagaaaatc
     3721 tgtaataaaa aagtatactt ttctggatta gaataaaata gcggcaatac ttcattatct
     3781 tccacgttct cataaaaagg ttttgtttct aaatcttggg caagcatttc agttagtgtg
     3841 cttttccctg caccgatcgt tcctgcaaca atgatcacaa ttatcggcat ccttcctgta
     3901 ataaaatctg ttcttcattt tactacttca tttatagaaa taaaagcctt gactttatct
     3961 gctccttaaa agctacttct ctaaaagtag ccaaaagtaa ctcctattca tgaaaataaa
     4021 ggctgtgaca aaagtcttgt cgcagccctt ttttcaaata aacagtattc tcctgccaac
     4081 acctcggtca caaggcaata ttcataaaac atgaaaagct gttttttaac attattcctt
     4141 gtaactcaga gctaaacggg agactcacaa cctctttatg ctctcaacat tttatctgtt
     4201 tttattcttc tattgtactt gatttgcgta caactaactg ccagtgcaga ttatgagcgg
     4261 tatcattgtc ttctactgcg catttcatga cacgtatcat cacactattt tcatagattt
     4321 tttctatttt tccttttatt ggtgattcaa ataaatcaga tttaaatgca tatgtttcgc
     4381 cgacttcaaa caattgttca ttttccataa gaatccctcc atcacctttt ataaggtcag
     4441 taatttttta acataaatca ctcgaaaaag cacaaacttg tcataaaaag tacttttcgt
     4501 atcaaaactg tcactttttt tggtaaggtt cttggaaaac gaagattttt ttaggagatc
     4561 atgacggttt tgatgtcaaa accacttttt atgaaacaaa agacgttttt tatttttttt
     4621 agcataaaat ttgtggtgga ggtacgtatg agatgaaaga taaagttgtg aacaaattat
     4681 tagaagcctt attcagcgga gacaaatcgg aagaagatat ggtgtatgtc caagtaaaat
     4741 ttgtcttaga agttttattg aataatcttg gaaaactagc ggtcgttcta gtcttttctc
     4801 tggtgacagg ctcatgggcg gaaacaggaa tcacctttct ttcttatatc tgcatccgca
     4861 gatatgctta tggattgcat tccgactctg aattcgtttg tctgctgtgg acactacttt
     4921 atttatgggg cgttcccttg gtgatgaaac atctgcaatt gactatctcc ttcccaatga
     4981 tggtcttttt gttaatcagc tgctttttgt tactgcttcg ctatggatca agaggtacag
     5041 caatcaatcc cattgaaccc gagaaacgtc ccccattatt aaagaaggcg atcagcatgt
     5101 ttctaatttt ttctctcatt acgttatttt tctcagcttc ttacttttct acctatttgc
     5161 tacttgggat tgttttagaa atagctacgt tgcttcctat tacaaactac ttgatgaatt
     5221 ttggaggaat ctttcatgaa aaaaacaatc attaaacaat taactaactt atctgacttt
     5281 tttgtatctg gctgctgctt tggtatgagt tctgaattca aaatccctga aaaattaaaa
     5341 aaataatacg ccaattgtgc tataatttgg taaaaatcaa tgggagctgt actttatgtt
     5401 tttatggtcc atagcgttgc aatatttgat ttacacaatt tgtatcttat tgattgacca
     5461 tcacatccga tacaaatatc tgtttgcggg agtcattctg atttcttgta ttttgattgg
     5521 atgggtctat tcgattttag ggatttttac tgctctaatt gctataggaa tgctgatgct
     5581 tacttttttc ttcttttcga cttcgcgtca acaattggtt tacgcgcttc cttttgggtt
     5641 attgacgtcg cttttaggag atcacttaac aagcatcggc gatttttttg ttttgaaatc
     5701 ttcggttatt gaaccaggag attcattgca gtattttcac attgtcttat ccgctttttt
     5761 atctgcttta ttagcttttt gtttaaaaaa atcgttagag acttggtttc acactgtgga
     5821 ccgccgtatg atcggtacga tcgggacatt gatattattt acatactata tcattatttt
     5881 ttatacccgt ttttctggtg aaacacctga tgtcttagct ttgaatacga gttttttcat
     5941 tctatatctg tgtgttggcc tgatcatctt ggtttattat tggaaaatct ctaataagaa
     6001 attagctgat cagttattag agcaacaagt caggatgcaa caggattata tcaaagatct
     6061 agaaaaaaac tatcaagact tgagagaatt caaacatgat taccaaaatc tgcttttttc
     6121 tcttcacagc tatatttcag aaggcgactt agaaggatta cggtcttatt atgatcaaac
     6181 gatattacct acacgccaga tgatgaacct ttttccggcc aatctaagta tgttggataa
     6241 tatgaaagtt cctgagatcc gtagtttact gtcattaaaa ctcatgatgg cacaggaaaa
     6301 agggttgatc gtccagcttc attttcctga gccaatcgaa ctggatacga aacatacggt
     6361 aaaccttgta cgtatgcttg gtattatctt ggacaatgcg attgaaggag ctagtgctgc
     6421 aaagaagaaa aaaatcgaat tgaccatact caagaagaat cattccgtga tgattcgtgt
     6481 gatcaataca acaacaaata cattaccgtt aaaccagttg aaacaaaaag ggttctcaac
     6541 aaaaacaaat ccaaaaaacg aaggccttgg cttgtttatc ttggatgaat tgacaaagac
     6601 caatccttat cttttccttg aaacatcaat tgaaaaccag cgtttttctc aaacgattta
     6661 tatacaaata aaataaagga gtaatgatat gattcccatt tatatttgtg aagacgatcc
     6721 aaaacaatta gaagttttat caacggtgat caaaaataga atcatgattg aaaacttaga
     6781 cagttatgtc catatttcta cctctgatcc ggaagaactt ctcaatgcag ccaagatcag
     6841 aacttcttct tttggtattt actttttaga tatcgaacta gaagacagtg aaatggatgg
     6901 tgtagcgatc ggtaaattga tccgtgaatt agatccttta ggaaaaataa tctatgtgac
     6961 ttcccatacg gaaatgtcga tgaaaatctt aaaaagcaac atcgaaccga ctgattatat
     7021 cgtcaaagaa gatctttatg atttaaaaga aaatgtcgag catatcctga gcaaaatttt
     7081 cgaagatttt caaatgtccc aaatccaaaa agatatcttc aaaatagagt ttaatgatga
     7141 gatcaaattt ttaccgatca aagacatcca atatttttct acttcgctag gagcgccaca
     7201 taaactggaa gtccatttga ctcatgccca attacaattc tatgagaaga tcaaagaaat
     7261 cgagaaaatg catcggaatt ttatccgttg tcataaatcc tatgttatca atacacaaaa
     7321 tgtgcggtcg attaataaaa aaaccagaga agtcacgttg gcaaacggcg agaccatccc
     7381 agcctctatc cgtggattaa agaaattgat ttcataaaaa gaaccgaata gtttggaccg
     7441 actaaatgac cagccgatcc aaacccttcg gttctttttt gcctatcagt gcaaaagcat
     7501 ttcctgtgca atttcacgtc catccattgt atctggataa aatgttggcc aattctccat
     7561 ttctttcagc aatacttctt gactttcatt tcctgcatat aaatgaaaat gttcggagtc
     7621 agccggtgca atcgtgtgat cactgaattg aatatatcta aaagcgccac tttccttatc
     7681 ttctgcttcg aatagatacc ttacgccacg gtttcctgcc tcgtaggtca agatttcttt
     7741 ccctacataa cgataatttg aacgtttcgt tgttccattc ttaaacgtaa atgccatctc
     7801 tttctcactg atcttgattg aagcaatatc tgtttgatag cccttcgtat aatattcttt
     7861 atattcttgt gctgtcttat cctgattcaa tttttcttta tattcaaaaa caggatcaaa
     7921 agtcccatct tctacatacg tatctactgt ttgccaagtt cctgcccaat ctgaaagaga
     7981 gcgatcttgt acatcctcgt cttcaaaata accgttgtag acgctctttt cttttttggg
     8041 ggtcaaagta tcttctagcg ggttttctgt ctctgtcgtt tttttcaacg cttcgaggtt
     8101 tgcttccatg atagaaagat agttttctcc attttctatt tgttcattcg tcaatccttc
     8161 caaaggattc aatacttcta aagatacacc tgcttcgttt gctaacgttc tggcaatact
     8221 atctttggcg ttttcttcaa aataaatata gttgattcca tgttctttaa caaagtgttt
     8281 cagttcagca attctcgccg cagacggttc ttcactagaa gaaagaccag caatcgatac
     8341 ttgattcaat ccatattcta acgctagata gttgaatgca gcatgttgcg tgacaaaaga
     8401 tctttgtttt gcttgcttaa aggtttcttg ataaagctga tggagtgctt gaagtttctc
     8461 ggtataggct gctgcatttt ttgtccatac ttcctgtttt tctgggtaag cttcaatcag
     8521 ctgatcacgt atgtttgcta cctgcttgat tgctaaactt ggagctagcc atacatgtgg
     8581 gtctagctca tgtgtatggc cttcttcccc gtgttcatgg tcatgatcat gtccttcttc
     8641 acttcccgga agtaaaagca taccttctgt cgcttttatc gtatggacat tgccttcttg
     8701 taatgttttt tggattgcgg ggacccatgt ttccatgttt tcatcattat aaacaaagat
     8761 atctgtatct tggatctttg ccatgtcttt agcagaaggt tcataatcgt gggaatcagt
     8821 ccctgctgga atcaataact ctacttctcc ttcatccccg acgattgctt ttgtaaaatc
     8881 atacatggga taaaaggtcg tcatcacgct caatttttct ttactgtcct cggctttccc
     8941 acttgccccg caagcagtta acatacctgc taaaaccagc atggccaata tacctatcaa
     9001 tcgtttcatt tatgacactc ctcttctcat cttctttcat ttgaatgttc cgattcgctt
     9061 ttcgcaaacc gtaatagtta cgttttagca acaggattta atttatcata tggttaaaag
     9121 aactgtcaag cgttttctta ttttaattga tgagaaagtt tatatgaatg attgacgata
     9181 tttttgcaat caacctctat cattttcctt ttatacccgc ttttgtctat aatgaagtta
     9241 tagataaagg aggaaaaaga gtgaaaaaag aaacagatac aacgaatcgt ttgatccgct
     9301 ttttaggagg aaaaacctct tactatgttt taggaatagt tatcttactt gcgctgatca
     9361 tttatttttt ccatcagatc tcgtttatat tcaagcctgt cggaatcatt atcgctacta
     9421 tcttgccccc attattgttt gcactgatct tgtattatct tttggaacca gtcatcaaac
     9481 gtttgagcaa gcacctttcg aggaacttgt cagtcattat cgtttatgtg attattttat
     9541 ttttattggg gcttggaagc atatggctta ttccttttct tgaagaacag gcaaagacat
     9601 tgatcagtag tttgccagat ttgtttcaag attttcaaga gagtctccga caatttttgg
     9661 agaaaacacc ttttgccgat tcatttaatc aatttttcgc ttctattgac gacgtgacgt
     9721 ctgatatagc tggatttatt ggaaattatt gggaaagtgg cgcacaacgg atcagcaaca
     9781 ttttttcaac tgttacagct atttttatta ctttatttac tggtccaatt gtcgcttttt
     9841 tccttttgag agatcctcaa aaattttatc agtcagtttt agcgattgtc ccaccagcat
     9901 ttcgtacaga ttttaaaaat ttgacaaaga ttgctaatca acaattgggt tcatttctaa
     9961 aggggcaaat cattgcttca tttatccttg gagcagtcta ctgggtttgt ttcttactga
    10021 tcggattaga atttgctagt gttttagcta tttctgctgg gttgttatgt atcattccat
    10081 atattgggcc gtttatcgcc ttctttccag gtttgatcat tgcattccaa gactctactt
    10141 ttatggctgt caaatttgtc attgtctggt ttgccgtaca acttctccac ggtgacttgg
    10201 tgattcctcg agtaatgggt gatcgtttac agatccatcc gattacgatc ttaatcgttt
    10261 tacttgtcat gggtgatcta atgggaattg tgggcgttat ttttggtatt cctatctata
    10321 cgttagtcaa attactcgtt acttttattt tccgtaaatt caaacaacgc tacaataaat
    10381 tttatggcga taaaggagag tatgaaaact cttcattttc tgaagaagat tattttaaat
    10441 aaaacacaaa acgtcgatct tacgagaata gctcgtagga acgacgtttt gtgtttttgt
    10501 tttaattttt cagcaaagca attgcctggt atggttttag ctccagactt tgatgaagaa
    10561 cagtatcgga ataattatcg ataagaatat tggcttctgt gaatccttct gggatggcga
    10621 tccttgtatc tttatcatag aaatttgtta atacaagcag ctgctgtcct tcaaattggc
    10681 gaagaaagcc ataaacttcc ggatgatttg cttcataagc atgataatct ccttgtgcaa
    10741 cgattggata tgtttttctc agccgaatca atttcttgta ataggacaaa atagaatctt
    10801 cagaagatag ttctttttct acattaatct cttctagctt gcctccaact tttaaccaag
    10861 gtttccctgt agtaaatcct gcttgttctg tgtctgacca ttgcatgggt gttcgagagt
    10921 tatcgcgaga ttttgctttg atccgacgaa acgcttcttt ttctgtgaat ccttgttcaa
    10981 ggagtaactt ataagcattc aaactttcta cgtcaatata gtcggaaatc gatgaatagt
    11041 ctgggtcgat catgccgatt tcttctccca tataaatata gggcgtccca cggttcaaat
    11101 ggatcatggt tgctagcatc tctgctcctt gttttcgata ctgatcgata gctacaaatc
    11161 gattgagcgc acgtggctga tcatgattat taaaaaatag agcattccag ccgttaccct
    11221 cactcatctt ttctccccat gtatgaaata gtcgctttaa ttctgcaaaa tcaaatggag
    11281 gagtagacca tttattccca ttttcataat cgactttcaa atgatggaaa ttaaagacca
    11341 ttgataattc ttctctacta ggttctgtat acaagataca attttcgatc gtcgtagagc
    11401 tcatttcacc gactgtgatg atagtggaat ccgtcccaaa cgttgcttgg ttcaattctt
    11461 ttagatacgt atgggtgatt ggtttgtccg tatattcagg tttgccatca ttttctttat
    11521 tatttttcaa ttgttcgtct ttaccgataa cattgataac atcgaaacgg aatccttttg
    11581 cccctttttc catccaaaaa cgaacaactt tgaatagttc ctctcttact gcttggttcc
    11641 gccagttcaa gtcagcttgt gtccgatcat ataagtgcaa ataatatttc cccgtatctc
    11701 caaatggcga ccaagcactt ccaccaaatt ttgataccca atccgttggc tcttctctta
    11761 aaatgaagaa gtcctgataa tgctggtccc ctgctagtgc ttttttgaac cattcatgtt
    11821 ctgtcgaaac gtgattcagc accatatcga gcatgatttc tatccggtat ttctttgctt
    11881 cggctattag ctgttcgaat tcctccatcg taccaaagat aggatcgatg gctgtgtaat
    11941 cagagatatc ataaccgttg tctttttgag ggcttggata aatagggttt agccaaatca
    12001 tgtcgatgcc tagatcattc agatacggga gtttttcttt gattcctttt aaatctccaa
    12061 ttccatcacc attactgtct ttgtaagatt tgggatagat ttggtaaatg actttgtctt
    12121 taaatgtcat ggatatttac ctccattcaa ctgatttatt acctaccaca acttatatat
    12181 acaagttatc atttattatt ataactgaac cgaaagcgtt tgtaaaattt atctttatac
    12241 attctaagag gtctgttgcc caataaaaaa caagagatca gacatgtatt tgtctatcct
    12301 cttgtttaaa atagcaaaat attcttgttt cttctataaa tggtgttcaa aagcttttat
    12361 ctacggcaat cagtcttctc aaatgtaaaa catgaggagc taattttatt tgagtattct
    12421 ttttgctcga tgcaggacgg cttttttaca acctctgatt catggtgttc aatcagctgt
    12481 ccttcggtat tagctcaaaa aacggcaaaa tatgaaaaac tattttgccg tttgtttctc
    12541 taatactcag gtcaaaccgc tgatttcaca acctctgttt ttattcattc gatttcaacg
    12601 catcaatcat atcgatatgc tttaatttga aatgggtaac aatcatcaca ataaccgtaa
    12661 atacgatagt taatcctgct gataagacat aagcccacca tgtgatcact aatggaaaga
    12721 tgacattctc catagacgct tgttgcaaga tgaagtcagt caatatatat cctacaccaa
    12781 atcctccgat gattcctaaa agagtaaaga tgatattttc tcgaacaatg tacatcgtga
    12841 cttctttatc aaaaaatcca aggactttta ttgtagataa ttcgcgtaca cgctcggaaa
    12901 tattgatatt agttagatta tacaagacga taaaagccag cagtcctgat aatacgacaa
    12961 agattaagac aaccgagtct aagttcgcca ttgattcttc ttgcgtttcg atttgtttgg
    13021 acatgaaaga cgtatttgtc acagcgtctg tggcaagcag tttctcggaa agcatttctt
    13081 cttcttttgt tgtcatctta tctgtacgca gcaaaaatgc attatccatc atcgattgat
    13141 cagtaactga agcataatat tcaggggaca tataaataaa gctacctaga tagtttttca
    13201 cgatttcttt tacttcgact ttccattctt tttgatcttc atcataaagc gaaatatgat
    13261 ctcctgtaga taagtcaaat agttctgcta ctttttgcgt aatagcgatt cctgttttag
    13321 gcaaggagcg tgggttctct tcaagatcag ttaaatggat aaaacgatcc aaatcagctg
    13381 ttttacttgg tacgatcact gtcagacttt gcgaagcatg tccttttttt ctcaattcta
    13441 cggtttgagt atgaatagct aggatctcat ttactttttc ttgcttctgc agcatatccg
    13501 ctgctttttg acgactatct tccgtggatg aatccaatgt aacgattgct tgatagtcaa
    13561 tgatcgttcc aaattgtttg gctgaaacag aacttagaga atctttcaat cccacgcctg
    13621 caaccatcag cccggcacat ccagcaattc cgataatcgc cataagcatt cttgacttat
    13681 atcggaagag atttcggtaa ctgatttttt gattaaagct aaggcgtgac cacagcggag
    13741 tgatgtattc aagaaaaatg cgtttccctg gcttcggtgc tttcggttga agcaatgcag
    13801 caggccgttc tcttaaatct ttgaataaaa cgatcattgc agcgccaaat gcggcaatga
    13861 agaatgcggc agctgcttgt aaaatcggcg gccagtcata aaaaataagc gcactcccaa
    13921 tatcataccg ctcgttagac agctcaaaaa tgatccttgg caaaagattc gttcctaata
    13981 tcgttcctaa aacaatacct atccctgagg ctagacttgc atagattgca tatttttttg
    14041 cgatttcaac tttcgtataa cctaacgcct ttaatgtccc gatttccctg cggttttctt
    14101 ctaccatacg tgtcattgtc gtaaaggtga tcaatgcggc aataaagaaa aagaaaacag
    14161 gaaaaacatt ggcaatcgca gcgatacgat cagacagatc accaaattct tgaaaaccga
    14221 cattttctga acgttcattg tataggtatg atggtttagt taaattttca attttttctg
    14281 catttcgatt caattcttcc tctgcagagg ccagttcacg ttctttctca actaattgcc
    14341 tttcttgttc agcaagttga gcttcttgtt gagataatgt ttgaacagcg attgttcgtt
    14401 gcgcttcagg aagctgctgg atagttgctg actgttgcgc taactgtttt ttagcatctt
    14461 ctaaccgtgt tcttgcttgc gttgtttgtg ctttgccatc cgctattttt tgctgtgccg
    14521 gttctaattc ttcgttggcc gattttttca gctcttctaa gcgttcttcg ggtcgatctt
    14581 gtaaatactt ttctgccttt tcttgatttt gctccatttt atctttgtaa gctttgctgt
    14641 acgtattcaa attctttacg tttgtaaaat caagatataa gacagaataa atatctgttt
    14701 taaaaacgga ttcaggtaaa tagacaaaat aatcgacgct accatttccg acgttcgcgt
    14761 atcctctctc caaattgttg atgaacaatg gagaacggac aaagcccgtg atggtatact
    14821 ctttttcttt caattcatct gaatcaatct gataaatatc accgatttta tacccttcat
    14881 cttccgcttt ttcatccaat acaagctggt ttggtttttc cgggagtttt ccatcagtta
    14941 attgtagctt gttctgcttg ttatttttgt tataagaaaa tatttgaatc acttcgtttt
    15001 tgccagtatt ggaataatag atctgttttc ctgtttctac ttttgcatct gggatctttt
    15061 ctgcttgagc aatatctttt tgtgtcaagc caccagtaga aacgatttgc aaatcagaaa
    15121 gtcctgctgt accaacatag tgatccatcg ttttttgcat gacaggtcca gcagttttga
    15181 cacctacaaa taaaagtgtt cctagcatga caataaggat gattgcaatg aatcgtcctt
    15241 tagattgccg aatttcgcga aaacctgctt taagatatgt tcttgttttc ataaaatccc
    15301 cctaccatac aatctcatca atggatgaag gatgatcatt taattcaaca gaccttactt
    15361 tagcatcatt aatgtgaatg actctatcag cgatgggcgc taaagcagaa ttatgtgtaa
    15421 tgatcaaaac ggtattgccg tgttgtctgc tagcgttttg caataatttc aatacttgct
    15481 tgcccgtttc aaaatccagc gcgcctgtcg gttcatcaca taaaagaagt ttgggatttt
    15541 tagctagtgc acgagcaatt gaaaccctct gctgttcgcc tcctgataat tgggacggaa
    15601 agttattcaa tcgatgagct aggcccactt gcctcaatac ctctacagga tcaagcgcat
    15661 caggagaaac ttccgttgcc aattccacat tttcttttgc tgttagatta ggaacgagat
    15721 tgtagaattg gaaaacgaac cctacatctg ttcgtcggta agcagtaagc tgtttatctg
    15781 aaaattgcgc aatatctgtg tcatcaataa tgatctgacc ttcatcaggt gtatccatcc
    15841 cacctaaaat attaagaatc gttgactttc ctgctccact tggaccaagt ataatcacta
    15901 attcgccttt ttcaattgaa aaagaaatat cgtcatttgc tgtaatggtc gtttctccca
    15961 ttttgtatcg tttgtattca ttttttactt cgacatactt cactctgatt cctccatttt
    16021 cacgatattt ctcgctatat ctatgcatcg aatgcgtttt ctcacactta tttattttac
    16081 cactgaattt ctctagacta aagaaaggaa tcctttaatt tagttgacaa ataaacgatt
    16141 tatgatttac ttacataaaa aacattgtta tttgaaagaa ggaacatcat gaatgattta
    16201 aaggaaaata tgatttttga tttatcaaaa actgcttttg tcgcgatcga catgcaaaaa
    16261 gagatcgtaa ataacggtac actctctcca cacactgcag catctattct gacaaacaat
    16321 gatttgttag taagaacatt gaaacgtacc gctgccttga aagttttagt gaacgtagac
    16381 atctccactt tcccttattt gagtcaacaa actgatatgg gtggaatgac tgcttctgta
    16441 cctccagaat tcactgattt acttttgaag gattctttga aagatacaga taatatgttg
    16501 actatcacaa aatacaatcc aagtgctttt tttggtactt ctcttgatct tcaacttcgc
    16561 cggcgtggaa tcgaaactat cattttaagc ggtgtagcga caacaaacgg tgtatatgct
    16621 actgcattag atgcctttca acacgggtac catatcgtgc ttgctgaaga tgcttgcagt
    16681 gatcgtgaca aagaatccca tcaattgttc ataaaaaaga tatttccgaa aactgcacga
    16741 gtacgctcaa cgaaacaaat aatcgaagct atccaacaaa gcaaataagt actggcacac
    16801 gtgattttca tttacttctt tttgatttca tgggaaaata accacaggat ttagatagga
    16861 gtatgaacat ggtgaaaaaa aagatcacaa tcaaagaagt cgctaaactt tccggcgttt
    16921 caatcacaac tgtctccttg atattaaatg gaaatacgga gaaattcagt ccgaaaactg
    16981 ttcagaaagt tttagctgcc aaagaagaat taggctatca gcctgactat tttgctagac
    17041 aaatgattac caaggaaacg aaaacaattg gtgtactcgt tcctgatatc acgaatccat
    17101 tcttcagtac actgatgcga ggaattgagg atatcttgta taagcagaat ttcgtcacga
    17161 tattatgtaa tgctgattct gatcatcaaa aagaaatcga atatctagcc gagctcacac
    17221 gtcgaggtgt ggatggattc attatcgcga cttctgctgt ctctacagat gcaatcaacg
    17281 aaaatttgaa aaaacaaggc cggcccttca ttgttttgga tcagaaaaaa tctgaaggat
    17341 ttagtgatgc cgtacgaaca gacgattttc gcggtggtta cctagcgggc atgcacttgc
    17401 ttagtctagg acatcaaacg atcgcccttg tctatcctga aaatccaccg gaaaatgtcc
    17461 acgctcggat tgaggggttt aaatctgctc ttgatgttta ccaaatccct cacgaccaac
    17521 tgatcctctt acctacacag ttctcaaaac aaggtggcta ccagatcaca gcagaacttc
    17581 ttgattctgc tgcaactggt gtgtttgctt taaatgatga attagctttt ggattatatc
    17641 gcggattaga ggaagctgga aaaagcatcc ctgaagacta cagcattatt ggctatgata
    17701 atatagatat gtgcgagtat atcaagccga aactgacaac gatcgcacaa ccaatcttcg
    17761 aattgggaca aacatctgcc aagttattgt tagatcggat ccaattccca gaaaaagaat
    17821 gggaagaaaa aagattacct gtacgattag aaaaaagatt ttcaactgca cccttgaaat
    17881 agctttcaag gtgtgctata tttttatcga actattaaaa cgttttacta aaacgtttta
    17941 aaaaataatt ttcccatcaa aataaatgag atagttggag gtttgtaaaa tgaacacggt
    18001 tacagtaatt ggaagtatta atatggacac tacccttcgt ttaaccaaca tgcccaagcc
    18061 aggcgaaacg atgcatgcgc atgagatttt tcacgctggc ggaggtaaag gtgccaacca
    18121 agcagtggca gccaaacgtt caggcgcacg gacatctttt attggaggcg ttggggctga
    18181 cagcgaagga caacagttat tagatctact gacaaaagaa aacatcgata catctgggat
    18241 agctgaaatc caaggcgcca caaccggaca agcaatgatt atggtagacg cagcaggaga
    18301 aaatagtatc ttgatccatg caggggcaaa taatgctttc catgaacaag aagtcctaaa
    18361 aaacaagcaa ctgattacaa acagtgactt tattattgct cagtttgaaa gtagcttaga
    18421 tgcgacgatc ctagcttttt ctattgcaaa agacgcagga aaaacaacga tcctgaatcc
    18481 tgcaccagct cgtgaaacga ttcctactga actacttgaa aagacagata tcattatacc
    18541 aaatgaaaca gaaacagaaa tcattacagg aatcagagtg acagatcata acagtttggt
    18601 cgcagcagcc gaaaaactcc atgaattagg tattggaaca gtaatcatta cactaggcag
    18661 tgccggcgct ttctatcata cagaaaaaga acacggtatc gtccctgctt ttaaagtgga
    18721 tgccgttgac acaacagccg caggtgatac atttattggc gcattaagca gcacacttca
    18781 gccagacctt agtaacttga aagaagcgat cctttatgga aatctagcct cttctgttgc
    18841 tgtgcagtct tatggtgcgc aaccttctat cccttaccgc gaagctttag aacaatcagc
    18901 agtctaaaat taacaatgag aggaagaaac aaacatgaaa aaaggaaaag taatcaattc
    18961 agatatttca cgagtaatcg cacaatgggg cactttgata aattaagtat cggggatgca
    19021 ggcatgcctg tcccctttgg tactgaaaaa atagatttgg ctgtctcaaa cggtcttcca
    19081 agttttttat ctgttttaga aaacgtttta gaagaacttg aggtacaatc gattgaattg
    19141 gcggaagaaa taaagacaat gaacccggaa atattggaaa aaatcaaatt attgttacca
    19201 gatacaccga ttagctttat cccacatgaa gaaatgaaaa aagagttgaa taactgtcat
    19261 gcatttattc gtacaggcga aatgacacct tacgccaata ttatattagt gagtggagtg
    19321 gtcttctaat ggaaacgaca atgaatcctg aacagatggt actgtccgag cagattcata
    19381 tgctgattga acagttggga ggaaaagaca atattgattc tgtccttcca tgtgcgactc
    19441 ggcttcgtat caaattgaaa aaacagccag tagccaatgc agaaaaatta aaacagcaaa
    19501 tcccttccat taagtatttc attttactcg atagatatgc agaaataatc atggatcagg
    19561 gattggctcc tgcttacaag gaattgacgc gtcaaatcga tcattcagct ccgaaagaaa
    19621 agctaaatcc gatcgaaaaa ctatttggtt tgatatcgga aatctttacg ccgatcattc
    19681 cgctgtttgc cggttctggt atattaaaag gtctggttgt tttagcgact acgattggct
    19741 ggcttagtga aacaagcgga acttatcata ttttgtctgc tgcgtcgaat gccgtctttt
    19801 attttctgcc aatctttctt gctttttctg ctgccaaaac gtttaaagtg aatggatata
    19861 ttgcggctgt cattgctgca gcactgattg aaccgaatct gacctcttta ctttcagaca
    19921 gtggcaaagc agctactgat tttctgggga ttcctgtagt actgatgcag tatacgtcta
    19981 ctgtcatgcc ggcgatttta ggtattttct tttattcttt tgttgaaaaa ttcctcaaaa
    20041 aatatattcg cgaaaatatg caattagtat ttgtaccttt actttcatta gttatcacgg
    20101 ttcctttgac gttaatggta ttcgggcctg cgggtgttta ccttggcgaa ggtttagctg
    20161 ccgcaattac ttggatgatg gatattaacg gaccgatcag tggcgcaatc atcgctggtg
    20221 gttggaatat tttggtaata tttggtatcc aatgggctgt aaaccctgtc atgatcagta
    20281 atatctctgc ttatgggttc gaccgaatcg ttccgttgac aggagcagcc aattttggaa
    20341 tggctggtgc agctttaggt gtatttctgc gaagtaaacg ttcaaaaacc cgttcgatct
    20401 ccggttctgc ttttgcttcg attttacttg cgggagtgac cgaaccaact gtttacggaa
    20461 ttgcgatccc attgaaaaaa ccatttgttg ctgcttgcat tggtgcagct gctggtggag
    20521 ctgtaatggg atttgcccaa gtgaaagcga tcgcttttgt atttggtagt ctgaccacat
    20581 tgcctgcatt catttccggt acttttttct ggtacttagc aggactggct gttagtctag
    20641 tcgtagcaat gatcactact ctcgttagcg ggtttgatga agacctaatg tcttatgaat
    20701 agttaatgaa aaagactgaa gtatgagatg tttatcacat atttcagtct ttttcttttt
    20761 aggatcatta tttttataaa tttttgtgat actttccaaa ctttggtata atttacatat
    20821 gcataaccat ttttatcccc acttgtttat ccccaaacaa aggtggtcta tgcaataaaa
    20881 tgaacgtcaa agaaaaacga atgaatgctc gttgcttatt tacaaattgt tttatttaga
    20941 atacacagac agatttatga aaagaaaaag cttttcgaca cgattatctg ttccaaaaaa
    21001 tgtctaatga atgctgaata agacagaaaa tcaatgaaag gaaaaggact agtttattat
    21061 gaaaaataaa aaaacgatac gtttgctagc tgctacttgg ctgattgctc cgtctgtttt
    21121 gtcgaccaat accgtatttg ccgtagataa tcaaatagct gatcaaacag tcacaacaga
    21181 tacgactaca tccagctcag ctactagtga aacaacggat tcttttacag aagacccaac
    21241 tggaacaact aactcaacaa caggatcgac cgagccaact gaaattgatc cggctgatcc
    21301 atcagaaaat gaaaagccag ccgagacata ttcccttaca attgctcctt ctttgattgg
    21361 taagatccaa ctgactgctt cgacagcgga ttcccctgaa cagcaacctt tggatattac
    21421 ggaaagtgga acggtagaag gtttattagc ggaaacgaag gtaacttaca ctattacgcc
    21481 agctgaaggt gaacaaattg cttcagtcgc tgttaatggt gccaaagaag taaattatga
    21541 tgcaaagacc tttacagtag gtacgaacaa tttatctatt actgcagaat ttaaagctgg
    21601 accggatact tcaacagaga aaccaactga tcctagtgaa gaagtcccta gtacaccaga
    21661 tccggaaacg ccaaacaaac cagatgtggg taataacaac aataataatg gttcaaataa
    21721 ttcaaacaat aataacaata attcgaacag cgggaattct tcgaatcaaa caaacccatc
    21781 tggatcgaat aacaatggaa atactcagag agaaccaaac catccaaaca atggttcatc
    21841 gaatggcgga acgaacaatg cttcatctcg tccaaataca gcaaatcaaa gcggtataga
    21901 gaatccatct tctgcttctt ctgattttgt tgtaaaatca ccaattgatg ctgtattgcc
    21961 tacaaataca acgaatgtcc aacaagcaat cgttcgagaa gcattcaagc atcttggaaa
    22021 accatatgta tggggagcaa aaggtccaaa tacttttgac tgttctggtt tgacttatta
    22081 cgtatatatg aaagcaaccg gtcattatat cggtggctgg acaggcgaac agcaatatgc
    22141 aggtacgcag attccagtaa gtcaggccca acctggcgac ctcgtcttct ggggaccttc
    22201 ttccggtgtt actcaccatg taggtatcta tattgggaac ggacaattta tccatgcgcc
    22261 tcaaccagga gataaagttc gagtaacttc tatttcagat ttcacgcctg attttgctgt
    22321 ccgagtaaac ttagcaggtt tacctgctgc ttcaggttcg ctgacaggcg gctcatctat
    22381 tttagatgga ttagatggct cgttccattt cagtcaaaac caaacaactg atcagttctt
    22441 gaaaaagatt gcagatgatg cacaggaaat cgggcaaaaa gaaggaatct acgcatcagt
    22501 catgatggct caagctatcc ttgaaagtgg atctggaaac agcttattat caagcgaacc
    22561 aaatcataac ctttttggta tcaaaggatc atataaagga agcagcgtga ccttcaatac
    22621 acttgaacaa gatagttccg gacaaagcta ccaaatccgc gcacaattcc gtaaatatcc
    22681 ttcttacaag gaaagtttgg aagactatgc cgacttgatc aaaaatggac tgactggcaa
    22741 tcctgatttc tacaaaccaa cttggaagtc ggaaacaaaa gactacaaag aagcaaccaa
    22801 atatttggaa ggacgttatg ctacagatcg ccaatattca caaaaattga acgcgatcat
    22861 cgaagcgtac gacctgacaa aatatgatga accgaaaaaa gaagcagcaa caactgaaga
    22921 agcaaacgct gaaatcctca atatgtctaa gcgattcgat gtgccaatca aatggacaac
    22981 agatggcgtg ccaatcacag gattagaatt ttcaacgata aaacgcgtca acaacgcttc
    23041 ttccatcttc cgtgtcgctt caatctggga tttgtggaac aattttacgg caagacagat
    23101 accagaaaca actactcgta cagttaaagc tgcaactgtt cctgtactaa ccttgttaag
    23161 tttagacaaa tcattctggc ttgatctgcc tttaaagaaa tagaataaat taaaaagggg
    23221 atgtgacact gtcacactcc ctttttaatt tattctattt ctttatattt attttgtatt
    23281 ccgttacaaa ctcgcgtact tggttaggtt ccagagtgac atctccaaaa ctttcaagtc
    23341 gctccgctcc tggcagttct tgagtctcaa atgtgatacc gccatgattt actaatttat
    23401 tcccgcgcat ttccggtcca tcttctccaa aatttgctgt aaaaatcacg attcctgaag
    23461 catctgtttt tacttggatc gatacttttt catctgggct tgtcaattcc gcagcattta
    23521 gtaaaccaga ttgttttttc aacaaaaatg gatgatcgat gccgcccact atcattgatt
    23581 ggcgaaaatc actggcaaag acctcaccta attttttagg acgttggaag tcaaatgctg
    23641 tgccacttac tgaaactact tctcctgtag gcgttgtatc tttattgagc gtagcaaata
    23701 atcggctatt caaccaaagt atatgttcgt cgattgactg tgctggatca ccggttaaat
    23761 tgaaatagac atgatttgta ggattgaata ctgttttgcg gtcactgatc ccttggaccg
    23821 tcactcgcca tgtatcatcg ttcgtcagcg tataccgtac ttctacatct aaagttccag
    23881 gaaatccgtt ttccatatct gggctagtct gatagaaaat gaccgatgct tcgttttcac
    23941 cattgatgac tgtataatgc cactgcttgg cttcaaagct aggtgcacca ccatgtaaac
    24001 aatgaccagt gtccgggtct gtttttactt cgaacgtttc atcatctaat ttgaatgtgc
    24061 cattcgtaat ccgtccagcc atacgtccga ttgaagcacc gatataaggg tctttttcta
    24121 gatattcttt tgcttcatca aaacctaaga tcaactctcg tttttcatta tcgattattg
    24181 tttgaaaatg aacaacccgt gccccaagat cactgacaga caaagatgtc ccattttgat
    24241 tcgtgatcgt aatcaagtga tagttttcgc caaaattttg ttcattgatt tccatgttcc
    24301 ttgcaccctc ttttctttca tttgcactga ttccagcata catggaaacc gttttcttaa
    24361 cagcttattc cgtgagtaac gagaaaaaat ttactatatt ctaataaaag accgtgaaaa
    24421 aaaggttgtg acaaaaatat tgtcacaacc tctttttccg aacaaacggt gttcaaaagc
    24481 ttgcatctgc ggtaataagc ccaaccaaac gaaaaatatg aggagctatt tttgcttggc
    24541 tgttcttatt acttgatgca ggacagcttt ttcacaatct ctttttcaat acgattccag
    24601 tatataacca tgtcgtcagt acatagtaga tgaaatacaa tacgaagaat atcgtaaacg
    24661 gaacccaaat atctttgtat ggattttgca tgaatagacc aaacatttgt aatccgaata
    24721 agacatggac tacacctaag attcctggtg ctaagaataa cacgcctact tctctacgga
    24781 tcgattgttt aagcaacccg cgtcgtgttc ctatcttttc aagcatttca taacgagcaa
    24841 tgtcactctt gcttcctgac aagatcttga acatcaaaca gctagcaagc atggtcaaga
    24901 aagctaaacc taggaagaat cccataaatt caaaaccaga gaatagacca ttatacactt
    24961 catacatttc atatttctgg ttgctgtact ctactttttg caaagatgga ttgttcattt
    25021 tattttgagc aacaagtgtt tcgattggtt tcaggtttgc ttggaagtct tttacctgaa
    25081 ctagctgtaa agtggattgt ggcaagttca gttgatcaaa ttctgattga ctgactacct
    25141 tgatttcttt ttcttgctgt tccggcaatt catagcttcg aagttcctct tgtacagtca
    25201 gttcattcat ttttttagca ggaacttttt ctttcgtgat cttcggcggt gttccatctt
    25261 catgttttat catgatcaat ggttgagccg caaattcact tgcattatag taaatcgttc
    25321 ccgcatcttc tttttgagta taagaagcag aaagtgttgg tgaaagttct ttgatttttt
    25381 gctgatcttc tgcccgagga ttattcatca ctagatcata tccagaattg ttttctgtca
    25441 agtctgcaat ttcattttta aaacctaatc ctaccgtcaa agcgcccagt gccaaggcaa
    25501 acagcatagc gaccattgag agcatttgtg tatattcacg aatacgaaag tttaactgtg
    25561 acaatgtgaa attgttcaat tttttcaatg aaatctgttc tgatttcttt agtaatgata
    25621 aaaagaaaat gatcacagaa tggaaaatga aataagttcc taatacgatc gtaactaagg
    25681 ctacccctat accaaagact tgataggtcc ccacgtgttt catcatatag taaccgcagc
    25741 ctagaaaagc aattcccagt actacttcaa ggaaaaacaa gaatttatgc tgcttgattc
    25801 ttgttggtgt ctgatccgca cgaatcaatg ctaaaatcgg ttttttgaca atcgaaaaag
    25861 cattgacaac agcagctaat aaaaacaaaa cagcaaaaaa caaaacagtg atcaacaacc
    25921 cgtgaatact aaaaggtgta aaatgcgaaa tattgagatc taactgatcc actaataatc
    25981 ggtggacgat acttgtcaat cctacaccga cagctgaacc cactaaagta gctgcgatcc
    26041 ctactaagaa tgtttcagaa aaaatcatct gtgcgatttt tctgcctttt gctcccagca
    26101 tcataaacat tgcatagtct ttttgccgca tcgtcatcaa aaaggaattt gcatataaaa
    26161 tataaacgaa tgtgatgatc cctagtaaaa cagaaccgaa tcggaaaatg ataactgtag
    26221 ccgcaacgat cgtattactt ttcaaaaaag cttcgttgct tgccattgat tcaaacatgt
    26281 aaaaaatagc agatgccata actaatcctg agaataacac caagtagtct cttaaacggc
    26341 tcttgatccc agtaagtgat aatttccaaa gcatagtcaa tctcccccta ctgttccaag
    26401 tttccaagaa tagatagtat ttctcgatag aaggaatcac ggctttgatc tccacgtttc
    26461 acttcttgat ggataccgcc atccttgatg aataaaatac gttggcaata acttgcagaa
    26521 aacggatcat gcgtcacaag aagaatcgat acatgatctt ttgtattcaa ttcgtccatc
    26581 gtatctaaaa gatcccgggc acttttggaa tccagcgcac ctgtaggctc atcccctaat
    26641 agaatcgttg gttgtgtgat caatgcacgt gcggcggcga cccgttgttt ttgtccaccg
    26701 gaaatctcag aaggatagct ttccaaaata tgagagatgg ataaacgttc tgcaattttt
    26761 tggacacgtt gcttgatttc ttttggtctg acgccttgta aagaaagagg aacagcgata
    26821 ttttcttgtg ctgtcaagct ttctaataaa ttgaaatctt ggaaaataaa gccaatctca
    26881 ttcgcacgaa aatctgctag ttgatttcct tttaatgtgg tcacatcttt ttgattgatt
    26941 cggatatgcc catctgttgg tttatctaat gtggataaaa tattcaaaag tgtcgactta
    27001 ccagaaccag aagcgcccat gatcccaata aattcgcctt tttctacatc gaagctgatg
    27061 ccgcttaatg cttgcgtctt tttctcattg ttttttccgt atacttttgt tacattctgt
    27121 acttcgacta ttttgttcat ttctttccct accctttaat tagtttttcc agtgctgttt
    27181 tcggcacgtc ttttttttcg acttcttcat acgaagtgac acctttattt ttgttccagg
    27241 tgatttttaa atatgctcct ttacgaagcg gtcgagtcaa ttgtcccttg aagtccagtt
    27301 ctttttcctt accctctttc gtatagccag gcaggatata tctatagttg actgtttctt
    27361 gtccagagtc tgattttgaa actgtttttg taccatctgt cgtaatttgt acatagtatt
    27421 cttctccacc cataactacg taatctgcga ttttcacccc tgcaagtacc acaacgatga
    27481 aaacaagtag accgatcaga agttttttca ctttttcccc ttctctctta ctttatatac
    27541 tgattataga aaaaagcgaa caattctgcc ttcgaatcaa ctatcattct tctttcaatt
    27601 ttgtcatttt ctttaaaaca actaaaaaaa gagttcaaga caataatccg tcctaaactc
    27661 cttcttccta tcttacaaaa agtatgtcac ttacggtctt tcatgtcgcc tgtattgata
    27721 acaggttgcg ttcctttgtc tgtaatgatt gagacaagta aattattgat caattggact
    27781 ttccgatcat cggtgaaatt gatttcttgt ccatcttcga tttgctctaa ggccatttga
    27841 gtgattgtga cagctccttc aacaatggtt tgtcgagcag acaaaatggc ttttgcttgt
    27901 tgacgttgga gcatggcact agcgatttct gttgcatagg ctaaatggtt caagcgtgtt
    27961 tcgattactt cgacacctgc tactgctaaa cgctcttgca gctctttttg caactcgtca
    28021 gacactgccg tcgtgtttcc tcgaagcgtc aaatcattct cattgaatgt atcatacggg
    28081 tattggctag cgatatgccg aatggctgtc tcactttgga tttctacaaa atcttgataa
    28141 tacgctacat cgaataatgc ctttgctgta tcaacgactt taaagactac tactgctgag
    28201 atttcgatgg ggtttccatc caaatcattg acttttaaaa cagaactatt gaaattccga
    28261 actttcaacg aaacagtcat tttttgtgcc aaaggtatcg taaggaaaaa gccattttct
    28321 cgaatcgtac ctaaatattg tccaaaaaac aaaattactt ttgcttgatt aggactgact
    28381 acagttgccg aacttaacaa caataacgtg atcaaccaaa gaaaaatact taaaaaaagt
    28441 gcccaaactt tcgcttgcca catacctaaa tagaagaaaa acaatccaac taaagctaat
    28501 acgaccaatc cgacaatccc tgcataacca ttgatataaa atgctctttt ttctctcatg
    28561 ctacttcctg cgctccttta tccttcaata aatatctaat gttacttttt taattttttt
    28621 tcgaatacgc gccattacac cttctagttc taactctttg tcttcagtga tgtaccaacc
    28681 gcttgcctgt gtccctccgg ctgcctgcgg taaataatcc aattttgttc gaacccagtg
    28741 cttttcttct gtaaaatagt cttctaccaa gacctctaga tccatccctg ctgaaagagg
    28801 caaatcttcc cgaacagatt taaagataaa tcgttccttc ttcccatcat acttcaatat
    28861 tcctgtatcg ataatcggta aagaataata atccagctct ttcttcaccg tcaataaatg
    28921 tttgaaaact tcatggtaca cttgctctaa ttggcgacct tctgaattgt tcgggtaatt
    28981 aaccatcact ttttctttgt ctggatcata gaaggtttgg cttagttgag tgatataagt
    29041 atgtaatctt tccatttctg tttttaactt ttctctttga ccttcttcta ccttcatata
    29101 ctctttcacc ctgttttctt tttagatatt ttctttctta ttttactata gttatgtgcg
    29161 ttaagcgatg aaaaacagca aagattggaa ggatctttgc tgttttttct taaaatatcc
    29221 agttgagtac aggatcaatc tgtttcattg tcctcttgat ccgtcgtaat attgatcgat
    29281 gtgtctttag cagtgatctt tagctttttc tgtccttgtt ctaacaaagt atttgttatt
    29341 ggctggtagt ctttttcaat ataagattca ccagacgttt ggatagtata gccactgttt
    29401 tccatctcat gcaaagataa attgccaccg tttaggatga cttttccttc tttgctgatc
    29461 aaactgtctt ctagatggaa gttgctgttt tcacctgtga cgatcaagtt atccacattg
    29521 gcctcatcta atcgaagtga gcctaattca tctttcgcag ttattgttcc tcctgtaaat
    29581 tcattgaacg atacccagcc atcatgtgtc ttagtattca cttttttgat tgatacttcg
    29641 ttgatatcaa ttgcactatt attcccttcg attgtcaatt cagataattc atgatctgca
    29701 gggacaacaa tagtgatttg tgcacttgtg tcttctaaac taatgattgc acctgttgat
    29761 tttttgactg cattcacagt caacacgcca tttttctcct ttatttctgg cttttctgtc
    29821 ttatcataag tcgtttttat ctcaaaatcc aatccgcgta tgaccgaaac tgtttgattt
    29881 tctgcatgga tgacgatttt gtttgcatcc ttgatttttt ttgtctcagt aaccatatcg
    29941 atcaaccgag gaccattatc ccaagtcaga ctcttttgag cgcctaatgt ataagttgca
    30001 cctgctagga ggccaccagt aagcatcaga ccaataccgg taatcaaaaa atgtttcaat
    30061 ctcaatttat gtgtcctcct tcaaacgccc gctgaatgca gatctctttt tgtaataaaa
    30121 cgtcgtccca tccatttaac aaagttcatc atgacataaa aaagcccttt tgttcctttc
    30181 agcaacagtg gcgaaataaa tactgcgctt cctgtggcga acagaccgac accgataaag
    30241 aataatccac tcagaatcga ttgtccaaac acactgattc ctgagatgat catgaatagg
    30301 ccaacaccta agatactgat acataaaaca tagatactaa aaatgagcgc tagtaaagca
    30361 accaatagtc ccccaataac caatataaac cccagtgcta gtggaatgag gacaggagaa
    30421 gcaaataaac cgataatgat taaccaaacc aggcgaattt gtctttttgg atttttcact
    30481 aactcgtttt ctgcttgttc ttcttctgaa aagtaactga tttttaattt taaggcaaac
    30541 tgctttggtg taccatattc atcaatgatc tgatctaatg tttttccaga atctaaaaaa
    30601 tattcctcat aatactggat caaatcaaaa cgatcgtctt caggaatttc ttgaagatga
    30661 tccacaactt cattcaaata ttcattcatt tgtgctctcc tccaataacc ggtctaaaga
    30721 atctcgaaaa acaatccatt catcaataat ttcttctaaa tgacgacttc ccattggtgt
    30781 caacgagtaa tatcgacggt ttctgccttc aaaaggttca tcataggtct caagatatcc
    30841 ttcttttttc aatcttctca aaaccggata tagtgtagat tcactgacag agagactttc
    30901 ttgtacgatt tttgttaagg catacccata catatcttcc ttgcttaatg ctgctagcac
    30961 agtaccatca agaagaacag ttggaatctg gatgtgcatt acgtcacctt ctattctcaa
    31021 gtgtaatatt ttatttcaat ctatattata caacatataa tatagtttca aaatcagttt
    31081 gtcaaataca aaaaaactga ctaaaagatt tgatcctttt tagtcagcaa aaaatggctt
    31141 ctctttgatt tttattataa cagtggcata atccaatttg tccacatcca gctcagtggc
    31201 atgataacga tcattgcagg tatcatgtca gctactggga acattttcac gttgatcatt
    31261 ctaaaaccgg tagcgaccat caagaatccg ccgcaagctt taaaatctaa gatcatgtct
    31321 ggtgtagtca atggataaat aaattttgcc aataagaaca aaatataaaa aataatgaat
    31381 tggggaattg ctatcacaga aacgacatac cctaaattac acgcaaaaat agctgctgtg
    31441 aaaaaatcaa ggacagattt agaaatcaaa atcgtactgt ctcctgtcat cccagaatct
    31501 aaacttccat agatccccgt accacttgca caaaatagaa caatgaccgt cactaatgtg
    31561 ctgataaatt catcgtgggt cataccaagc ttttcactag ggaagatttt agaaataggt
    31621 acttgcatca gcgcagcccc cttatttatc ccattaccta aatgaacaat caaaccaatc
    31681 gctgttccta tcactaaagc aaaaataaca gccggcatat ttttcatcgg cgcaatggaa
    31741 tagattccca tccccatcga acacacacca aaaaccatcg tcagctgtgc tttaaaatgt
    31801 tcacttaatt tatttcctac taatccgcca attagtccgc caaacaaaac ggaacctaca
    31861 ttgatcaaaa ctccagttgg catcaaaaaa ctcctctctt tttctacgaa gcgaaaaaaa
    31921 tcagaaaaat ttctgtaatt attgctttcg ctgcaagaaa gattgtaaca gacagagaag
    31981 attacaccaa ttcatttttt gtgttaaagt attctttatt ggaataagta ggaggaatat
    32041 gatggatatc cataaattcg aagtttttct tgatttagcc gaaacaatga atttcaccaa
    32101 aactgctgat cgacaattca ccacccaagg aaatatttct aaacagattc tttcgttaga
    32161 aacagaatta gacgtcaaat tattcgaacg cgcccataga aaaatcgaat tgaccgaagc
    32221 tggaagctta ttgctcccat atgtaaaaaa tgtcgtagaa caataccatg ctatgcaaga
    32281 agtgcttgaa acctatacga aagacaacaa tctttcatta aatatcttaa cgataccgac
    32341 aatgatcaat tataaaggtt tttccaaaat caccgagttt ttgaaacgcc atcctgaatt
    32401 tacagtccag ttgaaagaag tggaaagtgt cgaattaact tacaatgacg ccaatgaaca
    32461 tagtgacacg atccactttg ctagaagttt ccaggcccca ccaagttcga ttgagtggtt
    32521 gcctactgaa acagacgatt ttgtagcagt tctacctaaa aatcatcctt tagctagtaa
    32581 aaagaaattg gatctaagcg aactgaaaaa ggagaacttt ttgctccttg gccccactac
    32641 gaacttgtat caacctgtac tagatctgtg tcgcgaagct ggatttgaac caaaaatctc
    32701 ttataaagga gcaagaatcg acttgatcat caatatgatt gcaaatgaca tggggattgc
    32761 tattgttatg gaaaaaacag tcaagaatct attaaaagaa aatactgtga ttctccctat
    32821 ttctccaaca acagagagtt atcttgcatt tactcgtaaa gtcggtgagc attctttggc
    32881 ttcagataca ttttgggagt atttaaatca agaagaaaac taagccctac attttctgtc
    32941 catctatcca cccaaaaaaa gagagcgacg catgactttc gctctctttc ttgcatcatg
    33001 tccttgtttc aatgacacct ctaacatttc tcgtagttca ataagaaagc agcgattttt
    33061 atgccaaaag aaccgtaaga acatttccct aatcacaaaa aaacgactaa aaacccctaa
    33121 aaaccttcaa tagaattttt aggggtttta ttctttttcc tattgtttac ttaaccgtat
    33181 cattgctgtc gttcctactc cttcgatact gctataatca atacgtccat catgcagttc
    33241 tagaattttt ttaaccagtg aaagtcctag cccattccca gaaatttgac gacttgtatc
    33301 tccttgataa aatttttcaa acattcgatc tctggtctct tcattcattc ctacacctga
    33361 atcggtcact tccagtacaa tctctgtggc tgtctcaaat agtttgatat gaatctgtcc
    33421 attgatttga ttgtacttta tggcgttatc catgatattc agccacactt ggtacaaaaa
    33481 ctcttcattg cctgtgtaat ttactgcagc aagttcgata tccaattcta gctgttcttt
    33541 ctcccattta ggctgaaaaa aaacgattac ttctctgatt tgttcatcta atcgatactc
    33601 tttcttttcc agttggatac gctggttttc cagtttgttc aattttaaga tgttctctgt
    33661 taattgtgaa agctgcgtga tactttcgat aatccgatat aaaaatattt ggcgttcttc
    33721 gtcagagaga tttggggctt gtaacaattg aacatatcct tggattgttg ctagtggtgt
    33781 tttgaattca tgggatacac tggacacaaa gtcattcctc agtgtctcga tactattgag
    33841 ttcttggacc ataacgttga aatctttata cagttgctgt acttctgcta ctttctgctg
    33901 ttcatccatt cgaatcgaaa aatctcccgt tgctaccaga ctcatatttg tccctagcgc
    33961 actgattgga tgcaggatac gccgcccaac aaaaatcgat attcctgtac ccacgaccat
    34021 actgaacccc gcaaagacga ataacgggta taacgttggt tttccagccg attcagcagg
    34081 cgagatagaa tgtcgagaca ataagaaaat aaaaccgaga aaacacagca gtgtcactaa
    34141 gatcgaaatg aagacaatac tagcaaaata gatccataat tgtgaaaata gctttttttt
    34201 catctttaaa taaccgcctt atagcctagt ccccgtactg tgatgatttg aaaatcttcc
    34261 gtcttttcaa aacgggtcct taaacgtttg atatgtacat cgatcgttcg ttcttctgta
    34321 ttcgtatcta atccccaaat atcatccatc aactgttggc gagtgaagat cttgttggga
    34381 taagacagta atttatacag aagcagaaat tctttttgag gcagaatcaa cgaatgctga
    34441 tcttgtaaca ctgtataagc atctagctct aattttgttt gtccgattat caagctactg
    34501 ctgtaattga tctttgaacg tcgaagcaat gcttccacac gtaggatcat ctcattgaca
    34561 tcgatgggtt ttgtcatata atcatctgct cctaatttga acccgcgttt cttatcctca
    34621 aaatcggcct ttgccgtaat cattagaaca ggtgtgtcaa atctggtgct acgtaatgag
    34681 tctagcaagt catagccatc cattttcggc atcatgatat ctgtaatgat taattctata
    34741 cgtgtcgctt ctagtttttt cagcgcatcc tctccattca atgcggtgat gactgaaaag
    34801 cccgctcgtt ccaacacaga acggtaaagc aactgtaatt gcggatcatc ttctactact
    34861 aaaatacgat tcattgatct ccctctgttt tttgaaaaat ttctagattt tttcttgtag
    34921 ttcatcttca gttaacattt atttcgtata ctacgatcat tgttctgata tacttattag
    34981 tataccgaat atttcaatac gggagaaggg tgattatgct tcaattaaaa gatataaaaa
    35041 aatattataa agtcggcgaa accaccacca aagcattgga tggtgtgtct gtcgctttca
    35101 gacaaaaaga attcgtagcg attttaggtc ctagtggttc tggtaaaacg actatgctga
    35161 atgtgattgg tggactagat aattatgatt ccggtgatat ggtaatcaac ggaaagtcta
    35221 ctaaagactt taaggacagt gactgggatg cctaccgaaa caactctatc ggtttcattt
    35281 ttcaaagtta caacttgatt ggtcatctag gcattattga aaacgttgaa cttgggatga
    35341 cattaagtgg tgtttctaaa gacgaaaaac gaaaacgggc agaagatgca ttgcaccgag
    35401 tcggcttgac aaatcatatg cataaaaagc caaatcagtt atctggtgga caaatgcagc
    35461 gagtggccat cgctcgagca ctagccaatg acccagatat ccttttgtgc gatgaaccaa
    35521 ccggagcgtt agatacagaa acaagtatcc agatcatgga attgatccaa gagttatcga
    35581 aagaaaaatt agtgatcatg gtcacacata atcctgaact ggcccatcaa tacgcagatc
    35641 gaatcattga attttctgat ggtaagatct taacagattc ccatcctcac atcgaacgac
    35701 caaaagatga tcaatttaac ttacgcagaa caaagatgag tttttggaca gcgttaaagc
    35761 tttccttcaa caatatccga acaaaaaaag gacgtacttt cttgacctcc tttgcttcca
    35821 gtattgggat catcggaatc gcgatcgttc tgtccctttc ttctggattc caaaaacaaa
    35881 tcgataacac gcaagctgaa acgatggcga aatttccgat tactatttct aaggtaacga
    35941 ctaaccagac tcgtgacgat gccggattgg gtgcaagcaa agcggattat ccagacagca
    36001 aaacgattac tgcaaaagtc agcgaagaag ataaagcaca gcacacgaat aagattgatc
    36061 aaacatacgt cgattacgta acagacatcg atcctaactt aagtaataat atcggattta
    36121 cccgtactac aggaatcaat cttttacgtg atgtaaatgg caaagtacag cctgtcagct
    36181 tctcgaatca aaatcctgat acggaatctc tttctttatc tagtacgatg tcagcaatga
    36241 caggtgtggg agtgtcaagt ttccctacac agcttgacac tagcaaagaa aactttttaa
    36301 aagacaatta ttctttactt gccggaagtt atccagcctc agcaacagat gtcgtgctga
    36361 tcgtagacgg caataataat actaatatca acgcattgaa gaatcttgga tttgatgtga
    36421 aagaagacga aaaacttgat tttgatgata tcgttggtac aacattcaaa ttagtaaaca
    36481 acaatactta ctatacaaaa cttccaactg ggaattttat ccctaataca gattatgatg
    36541 cgatgtatca gaatgcttct gatgaattga agatctcggg gatcctacgc gtgaaatctt
    36601 cttctacaat gaatctctta tctccaggaa tcgcttatag cgatcaatta acgactcaaa
    36661 tcgtcaacga aaacaaagaa tcagaaatcg tcaaagctca aagagacagt ggtgtaaatg
    36721 tcttaactac tgaaaaagtt gacgaaaatg ccaaacaaac attgcttagt tatttaggtg
    36781 gagacagctt gccttcaagt atcatgattt atccgaacaa ttttgaagac aaagaaaaga
    36841 tcttggatta tctagatgat tacaataaag gcaaatcaga tgaagataaa atcatttata
    36901 ctgatttagc tggaacgatg actgaactga ctggcggatt gatggatgct atcacttatg
    36961 tccttattgc ttttgcaggg atctctttag taacaagtat gatcatgatc agtatcatta
    37021 cttatacatc tgtgattgaa cggacaaaag aaatcggtgt actaaaagct ttaggtgcac
    37081 gtaaaaaaga catcactcgc gtatttgacg cagaaacgtg tattttaggt atttcttctg
    37141 ggatattagg tgtgtttatt gcatggctag ctacgttccc tatcaatagc atcttataca
    37201 acatgacgga tctaaaaaat gttgctcaac taaatcctgt ccatgcgatt attctagtga
    37261 tcgtctctac tatattgacg atgcttggcg gtcatcttcc tgcacgaatg gcagcgaaaa
    37321 aagacgccgc tatcgctttg cgtgcagaat aaggttgtga caaccacatt tagatttgag
    37381 tcataagagc gctgaaatag tagaaaacag caagaaacga ggaagtaata tgttccttgt
    37441 ttcgcgctgt tttttttaat tattttttat aattctggta tacttttctt tcctttgtac
    37501 cacaactctt ctggcgtata cctgtctttt ccatttatga atactgttcc atctgcttca
    37561 atcgttactt cagtcccaat ccacatatta cgagaaagtg cgagaagatt ttttcttttt
    37621 cctcttcctt tttttccaaa ttgcaaggca tcggttatct cttctgtcca atgagatttc
    37681 acgtatttta cttctccgtt ttcaaatgta actttcaaaa tattcgctat attttccact
    37741 tttactgctt taggaaatga ctcctccatt tttttcactt tccttcctcc aacactaagt
    37801 atgcgctttc ttttagtgat aagtatatca tagtttattc tattatcaaa aaaacgcatc
    37861 cattccattg tagaatactt taccgaacaa gttgaattgt tttcctcttt ttcacctttt
    37921 actatagata ggtaaagaca actaaggagg aatctctcat gacagatcaa ccgtatgatt
    37981 taagaaaagt catcgaagaa ctaaaaacac ttccaggtca atatcacgaa acagatattg
    38041 aaatcgatcc tgaagcagaa ttatctggtg tttaccgtta tatcggtgct ggcggtacag
    38101 taaaacgtcc gactcaagaa ggaccaacta tgactttcaa caatatcaaa ggtttccccg
    38161 gcacacgtgt gaacatcgga acaatggcta gtcgtaaacg tgtaggtgaa attttgcacc
    38221 atgattatcg aacacttggt cgtttcttga aagacgctgt agaaaatcca atcaaacctg
    38281 tgaaagtaga caaagcagac gctccagcac aagaagtcgt tcatctagct accgatgcag
    38341 acttcgatat tcgcaacatt ttgcctgcac ctacaaatac tcctgaagat gctggtccat
    38401 acatcacaat gggtgtagtc ttaggatcag atccagaaaa aacaatgagc gatgtaacga
    38461 tccatcgtat ggttctagaa gataaagata cgatcggtat gtacatcatg cctggcggac
    38521 gccacattgg tcacttccaa aaacaattcg aagccttgaa taaaccaatg cctatcacta
    38581 tcaatattgg tttagatcca gcaattgcca ttggcacgac tttcgaacca cctaccactc
    38641 cacttggcta caatgaacta tggtgtgcag gagctttgcg taacgaacct attcaaatcg
    38701 ttgatggtat agcagtcgat gaagtgggta ttgctcgtgc tgaattcatc attgaagcag
    38761 aaatcatgcc aaatgaaaca atgcaagaag atatcaacac gaactcagga aaagcaatgc
    38821 cagaatttcc tggctatact ggggatgcta atccagctgt acaagtagtg aaagtcaaag
    38881 cagttactca ccgaaaagac aatccaatca tgcaaacaac gattggtccc agtgaagaac
    38941 acgtatctat ggccggtatt cctacagaag caagtattct tgccttggtc gataaagcta
    39001 ttccaggaaa agtagtaaat gtctacaatc ctcctgcagg tggtggtaaa ttgatgacca
    39061 tcatgcaaat ccgtaaagaa aacgaagcgg atgaaggtat tcagcgtcaa gcagctattc
    39121 ttgctttatc agccttcaaa gaattgaaga cagtcatttt agtcgatgaa gatgttgata
    39181 ttttcgacat gaacgatgta gtttggactt tcaacactcg tttccaagga gataaagata
    39241 tcatcgtgat cccaggaatg aggaaccatc cattggaccc atcagaatta ccagaatata
    39301 atcctggctc tattcgtttc cgtgggataa gtgcaaaaac tatctttgac ggtacagttc
    39361 ctttcgatat gaaagaacat tttgtacgtg caaaattcca agaagtagaa gattgggaaa
    39421 aatatttgaa ataatgaatg atctgcaact gttttgacat cataaaaagg agtgcggaaa
    39481 atggaacaat tggcacaacg gaagaaaaaa atcgtgattg gtgtaagtgg cgcttcaggc
    39541 accatttatg ccatcaacct agtgaagaaa ctaaaagaat atccgatgat agaaacacac
    39601 ggaatcatca gtccatgggc aaaacagaac ttaaagctgg aatccgactt atcactaact
    39661 gaattcgaaa gcctgtttga ttaccattat tcaaacaaag atttaggtgc tgctgtcgcc
    39721 agcggatcat ttttgaccga tggaatgatc atcgtaccgg caagcatgaa aacagtcgca
    39781 ggtatctctg ttggtttagg cgacaacctg attgcacgtg ctgctgatgt aacaatgaag
    39841 gagcaacgaa agttagtcat tgttcctcgt gaaacgccat taaatgccat tcacttggaa
    39901 aacttgacta aattagcacg actaggtgtg caaatcatac caccaattcc tgctttttat
    39961 aatcagcctc aaacgatcca agatcttgtt aatcaccata caatgaaact tttggatcaa
    40021 tttgaaattg taaatgagca ttcaaaacgt tggcagggtg attaatatgg aaaaagaaac
    40081 gatagttgaa gtaaccaaac taggtttcac gatccaagct gctgttaaag taatcggtaa
    40141 agacttattg atcactttaa caggcggaga tacaccacat atcggaacag tcactacatt
    40201 ttctcgtgat acagagatgc aaactgtacg tttccctagc cacgatggtc ggttccataa
    40261 agacgatgtc ttagccgaaa aaatagctgt gatcatcaaa actgccgttc cgggaagttg
    40321 tacgatcact tccggtatcc atgttgacca tatctccaat gcacaaatca acgcctcttt
    40381 tccgatgtca gaagagttag gttacaagat tttagattgg ttggaaaaaa tagatttcca
    40441 tatcaaagaa ccagtttatt ataaagatgg tgaaaaacca ttatgaaaga agaggttgtg
    40501 aaatcagcgt tatgacctga gtatgagaga aaaaaatgga aaaatagctt ctcatatttt
    40561 gccgtttttg agctaatacc gagggacagc tgattgaacg ccgtttatca agaggttgtg
    40621 ataaagccgc ttcgtttcga gtagtaagaa aaattttgta aacatgggtt tccacatttt
    40681 tgcataaatt tgacttacta ccgagaaact ggcttttgaa caccgtttat caagaggttg
    40741 tgacacgtct tttgtcacaa cctcttttat ttttgcttca ctgtaactgc tacaatatca
    40801 ccgatttctt ttccgatgtt tttacgaata tcttttcgta gtccaaggat gtagcagact
    40861 gaaccatctg gatttttcac gcccatattc acgatactgc cttcatatgg cacattgtca
    40921 aaagttgctt ggactttaac tcttccagca ccgaattctt ttcttatatc atacggaaaa
    40981 ataatatatg ccccgccctt gccgacttcg gaagcataga tttttgattc aaaagaataa
    41041 atttccctca ttttatttct cctatttttt acatctagta tagcatagca aaaaaaagaa
    41101 ggaactgtga caaaagtctt gtcgcagttc cttttttcga ataaacggtg ttctcctgcc
    41161 aactcctcgg tcacaagtca caatagtcaa caaacatgag aagctgtttt ttgaaattgc
    41221 tccttgtgac tcagagttaa acggcaggct cacaacctct tccttaaacg gtgttcaaaa
    41281 gcttgcatct acggcactaa gcccaatcag atgaaaaata tggagtgcta tttttatctg
    41341 attgttctta ctgcttgatg cagagcagct ttttcacaac ctcctacatg gtgttcaaaa
    41401 tattattcgc cttttgcttc tttcactaat tttgcgaatg cttgttgttg gaattcagca
    41461 gctaaggctt tcgtacgttg ttcttgctct gctttgctca tttttggatt ttcagtcatt
    41521 gcttttacca taccgtcttg aacataagct tttgcttcac tttccatcgt actttgctgt
    41581 ttcttcacta attcagctaa cttggctgct tggtccgtac ttaattctac ccatgtctct
    41641 gggattttga atgtattcac tcggctgtca tattcgtgat tgttatcagc aatattgaac
    41701 cagaatttat acatgtcgtt tttgtattcc caataagtag ttttcgtcac tttttcagca
    41761 tcgccgtctg tcttttctac tttatttgtt tcgttatccg taccagttgc ttttggtttt
    41821 tcttgttttt catttgttcg gtaaagatac actttttctt ttccattccc taaagcttta
    41881 tacaaaagca tatctgctcc ttgggaatca gcactggaaa caattttttc tgtttttgtt
    41941 tccgttactt tttccattcc aaagtgattg gacaaattag cgacgatcaa acttagtgaa
    42001 gcgacgaaga ttagtccgaa aatcaaagat aaaaaggttt gccatgtttt tttagcgaac
    42061 acgttcgtta aagcaaaagc aagcaagctg acaatcaaaa ctccaataat catgcattat
    42121 cccccgcttt cattagaaca ggttcttttt tcttcaataa aaaggcaata ataaagccaa
    42181 gaatcccaaa gatgatcgct acgataaacg cggcatggta acctgacagt gtggcattga
    42241 ttgcctgatc tttataagct aatggcgtat tatccaatac agatttgctt gggatatttg
    42301 cttttgtcac attcgtcaac acactgatca aaatagctgt accaatcgag cttgcgattt
    42361 gacggaatgt attatttacc gctgtcccat gactgatcaa gttatttggc aatgcattca
    42421 taccagaagt cgttaccggc atcatgacca tggagatccc aaacatacgg atcgcataaa
    42481 ggatcacgat atataaaact ggagtcgttt ttgtcaagaa agcaaatggt gcagttgccg
    42541 ctgtcaaaat gaacatccct gtgatggcta aacgtttcgc gccgtattta tcgaaaatcg
    42601 cacccgtcac aggcatcata gcccccatga tcaatgcacc cggcaacaac atcaagccag
    42661 aatggaatgc tgattctcca cgaatatttt gaatatacaa tggtacgacc atttctgccc
    42721 ctaccatcgc catatttgtt acaccagcta aaacagctgc aatcgtgaat gtagatgatt
    42781 tgaatacacg aagttccaag aatggatgtt ccaaatgtaa ttgacgccat gagaacaagg
    42841 cgatgaaaat cacaccaaca actaagaaac caattacttt caagcttccc cagccgtcat
    42901 ctcctacact agaaaatccg taaagtaaac taccgaatcc aatcgttgat aaaatagcgg
    42961 ataaaatatc aatgctagga tttgacaatg gaataacact tttcattagg aagaatgcta
    43021 aaaccaagac aagaacaacg attggcagta ccataccaaa caagtcacgc caatggtagt
    43081 tatcaatgat ataaccagat aatgtagggc ctaaagcagg agcaagtcca ataacgatcc
    43141 ctgacatccc cattgctgat cctctttttt ctggcgggaa aatagatagc atgatatttt
    43201 gcaataatgg catcgatact cccacaccgc aagcttggat caaacgaccg attagtaatg
    43261 tactaaaatt aggtgctgta aagcaagtaa tcgttccgat caaaaagatc gtcatggcag
    43321 aaagatataa atttcttgaa ctgaatttat tgatcagcca tgctgttatt gggatcatga
    43381 tcccgttgac tagcaagaaa ccagtcgtta accattgcac atcagacgct gaaatatcga
    43441 aagctttcat caatgtagga aaagctgtcg tcaataaggt ctgattcaaa acggtacaaa
    43501 atgtaccaat taataagaca acaactaaaa gtgtccgatt atatggtttt ccgtaaatat
    43561 ctacgggttg gttgttactc atatttctcc ttctttctga attttttctg aaactactag
    43621 aatactttag tcctaaattc gctatttgtc aacctacttg acacataagt taatacggat
    43681 ataattaagg gaagcaagag gacaaaagga gtgacaaaaa tggttggggc ttcccttaaa
    43741 cgtttgttgg aaaatgatca attggttgtt ggcatcagtg aattaagtga tatcgtaggt
    43801 gtgtctccac gtcaattaag gtattgggaa caaaagggat tcattcgttc gatcgaagct
    43861 gatgcgaatt gtcctagaaa atatcgttta cctacagtca taaaagtaga actgatcaaa
    43921 aaatatttag atgacggatt tactttgtca aaagctgcag aaaaggcaga aatccgccaa
    43981 aagaaaatgc accatgtccg taaagttttt tcaaaagcaa tcaaagatat cgaattgatc
    44041 gacgaacgct atacgatttt acaaatcggt aacttcaaag aagagaatgc taagatgtac
    44101 atcattcatg acaacgagac agacgaatta acttacaagc tccttcctgt cgatgaaaaa
    44161 gctgactacg aacagttgtt aaaagaactc taaacgccac taatctccta agtaccaagc
    44221 tttttaataa gtagatgcta cataaatact tgaaaaaagg cctgtttgaa cataagaata
    44281 tccgaacggt gatctgcgtt tctttcatat agaaaggaat tctccatcac tgttcggata
    44341 tttttttatt tttttcggtt actttcttct aatacatctg ttagccaatt tgcatattct
    44401 gtttcccgat tgatcgcatg cgctaaaatc aggtagtgtc cgtaattttc atgtttttct
    44461 ttttcagtag gaaagatcgt tttttttcgc tctaatagat gaagtcgttt ttcttcatga
    44521 aggtcacgct gctgctgaat aatttctact aatgccggat cattcacgtc tttgacgaaa
    44581 tacaatttca gaacaaattc gtctcgatta accggtagtt cattggtggg tgtatgaatc
    44641 cactctgcca attgttcctt cccttcttct gttaattcat aaactttctt ttccaatttt
    44701 tcacctgtga tctctacttg atgctgaatg attccttgct cttccatttt tgcaagttca
    44761 ggataaatct gactatgttt tgcttgccaa aattctccta tttcattttt gaacgattga
    44821 ttcaattcat atcctgtcat cttcttctta cttaataacc ctaacaaaat atatcgaagt
    44881 gtattttttc ttgccatcag ttttccctcc ttgacaaatc tttaaatcca ttctatcata
    44941 aatgagtaat cgaaaacatg tagtttatta catgttttaa tttataagga gatgcttaaa
    45001 catgaaagaa tttaaagaat tggaagattt tattggaact cactttatct atacgtatga
    45061 caatggttgg gaatatgaat ggtatgccaa aaatgaccat actgttgatt accgtatcca
    45121 tggcggaatg gtcaaaggcc gttgggtaaa agaccaagaa gctgatatcg ttaaattgac
    45181 ggacggcgta ttcaaaatca cttggacaga gccaacaggg acagacgtgg cattggactt
    45241 tatgccaaat gaaaagaaac ttcacggaat gatctttttc cctaaatggg ttgaagaaca
    45301 tccagaaatc actgttactt tccaaaacga acatatcgca gaaatggaag cagctcgtga
    45361 aaaatatgaa acttatccaa aattacttgt tcctgaattt gctacgatca cttatatggg
    45421 tgatgcaggt atagacaatg aagatgttat tagcgaagaa ccatacgatg gaatgccaga
    45481 tgatatccgt agcggaaaat acttcgatga aaattataaa cgagtaaaat aaggttgtga
    45541 aagagaggtt gtgaaatcag cgttctgacc tgagtattag agaaagaaac ggaaaaatag
    45601 ttcctcatgt tttgccgttt tttgagctaa taccgagggt cagctgattg aacaccgttt
    45661 atcaagaggt tgtgaaatca gcgttatgct ttgagtaata agaacgctag ttagaaaata
    45721 gcttttcata ttttctaggc tagtgggctt attaccgaga agcagccgtt tgaacaccgt
    45781 ttatcaagag gttgtgaaat cagcgttttg acctgagtat tagagaaaca aatggaaaaa
    45841 tagttcctca tattttgccg ttttttgagc taataccgag ggtcagctga ttgaacaccg
    45901 tttatcaaag attgtaacaa ctgcatattc acacagttaa attagtgact tcaaaatgaa
    45961 ataatgctcc cagcaaaaaa ttaggctggg agcattattt cgttattctg ttcatcaaaa
    46021 atcagcgttt tgattccatt tcatcacaag ttcctcctca tttactgctt catctttttg
    46081 ctgtgtttga attgtaaaac cttgtgaaag atagaaatga atagctgatt gatttttttg
    46141 atagactgtc aaagtcagtg ttttattggt ttcttttatt tttttcatta gttgcgtacc
    46201 gattctttgt tgccggtatt cccttttcac aaagattcct gcgataaact gatcaatcac
    46261 cccagcaaaa ccaataattt cttgatctat ttctgctaag taaatcactg catctggtaa
    46321 agctttccta acagattcta cttgattctc ccaataagtt gatggaatga attcatgaga
    46381 atccaagtta gcatgcagcc aaatcgatag aacagattcc agttctttgg cagacaattt
    46441 tgttgttgtg cggatcattt tttctctcct tacttattca ttgattttaa aataaaaacc
    46501 atttttttga agctctttta caagttttcg cccctcaaaa aagtatatct tctcttgttt
    46561 tacttttcta ataccaaaag aaacagcaac tttaggatca tcagctgaaa cgattcgata
    46621 agttccacca ggcaattgat ccagcttgac tttcccatga tggtcgcttt gtactgaaaa
    46681 cggcacacca tttctagtaa gtgttttttt cttatgtttc aaaatgaatg aactaccatt
    46741 taccggtttc cctgacgaat cactaataat aaatgaaaaa tcaagcactt ttttacttaa
    46801 tctatactga tagattagtc gtccgataaa cactaacagt atgactacag ctattatcgt
    46861 tcctgcaaga ataaaccatt gccgcatggt tctttcctga tttccttttc cttcttcttt
    46921 ttttaccgat tcgttataag gaatccgatg tcctgtcact agcaaacgat gcgtgttgat
    46981 catatacggc gtacatgtaa gcaaggtaac taagtcttct ccttctgaaa tcgttagaac
    47041 agacgtgtca tctggcagta ccacttgtat atttttaact tgataagcca atttctcccc
    47101 caaaacagtc aaaataaacg tgtctccgtt ttctaaacga tctaattcgg taaataaccg
    47161 tcgattaggt aaaccgctgt gagcagagat cactgaatgc gtcgaatttc caccaagcgg
    47221 gaaagaggtt ccttgcaaga cgcctgctcc attttcaagg atcctaccat tgagccgatc
    47281 ataaagtgaa atatttaatt ggatcttagg tatattgata cttccgatca gccattcctc
    47341 taattggctg gatgttgtac tttcatttct gttcttttca ttgaaaggat cagtaccagg
    47401 attgaatcct tggtcagtta atcgttggtt tttctcctcc attttctttc gctgcacttc
    47461 aatttcagct gcggtccgtt tttgtacttg ttcgatacgt ttttgatcaa taaaactatt
    47521 taaagaatcc acataaaatg gatataaagc gatcagtaac cctacgacga tacatattaa
    47581 taaaaacaaa cgaaacaaaa gtcgacgaga ctgtttttgc ttactctgct tcacatgtgt
    47641 cctcccttgc aagttttttt gttctttctt ttattatatg ggttcaggaa aaaaatagaa
    47701 aatgaaagcc gatgaggttg tgaaaaagct gtcctgcatc aagtaataag tacagcccaa
    47761 aaaaatagct actcatattt tttgttgggt tgggcttatt accgcagatg caagcttttg
    47821 aacaccgttt aaggaagagg ttgtgaaaac tgcgttatgc tttgagtaat aagagcgcta
    47881 gtcagaaaat agcttctcat attttctagg ctagtgagct tattaccgag aagcagctga
    47941 ttgaacaccg tttaccgaga ggtcatgaaa aagctacttt gtttcgagta ttaagaaaaa
    48001 ttctgtttca aaacaaggag atgcaacaaa acttatgtcg catcctctct ccttagaact
    48061 ttcacttatg tttttcttgt aaaattcata aatattttca tgaattttct aatttcttgc
    48121 ctacctctcg cataggatat atgatgaatt tatctaaagt ttgcaaagga gttcgacaat
    48181 tgaaaaaata tggcccattt ttagcaattt ttttcattgc tttggcattt ctcatgcctc
    48241 atttattcac acataaacta attttgggtg ctgatgcccc attccattac aatcggttct
    48301 atgatgccgc gcaacaaatt aaatatgggg atttccatta ttttccttcc ctttatggat
    48361 tccagcaaag tggcaggatc gtgaatgccg tttacggccc atttttcgct tatttacaag
    48421 gattgatcgt gttgcttgca ggtagctggt ttcattatca gattctttca aatttcattc
    48481 tttatcttat ttcaggattt tctatgctga ttttactgag atatgtcaat gttcgaaatt
    48541 gggtaagtgt accagtagcc gttttattca tgagtacgta ttctattcaa tactggtcta
    48601 tcaaccaagg attcactagc tgggggactt gtttttatcc tttatgtatg atccctattg
    48661 ctgatttcgt ccttcataaa aagttccctg ttatcaaagt cgctgtctca gtgggactta
    48721 tgacacagat ccatttactg tcttcgatca tgttagcttt gatgtatatc cctttttatc
    48781 tttattactt ttttaaccag actgaaaaag gaaaagcact gcttcaactg attaagtcgg
    48841 tcttgcttta ttttgttctg acagcaaata tttgggcagg attagctatt gtttacagtg
    48901 ggaataagat tcttcctccc tttgttaaca gagaaatgag tcaaaaggcg atagatctgg
    48961 atggcagtta ttggctccat taccctaagg cctttcctat attgatatta tcaggttttt
    49021 tgctttttat tttctttcaa caaaagaaca ccttattcca aaaaatcgtg ttgtacacaa
    49081 gtcttgtttt cttttttctt tctactagct tgattccatg gacgacattg atcgaaaaaa
    49141 atgtgccttt tattagtttg atccagtttc catttcgatt tttcgtgcca tttacgctat
    49201 tgcttctact ttaccttgcc ctttcactga accagtggtc tgaacaaaag tggttccgtc
    49261 ttttaagtat atttggcatt cttatttttt cagcacagac gatccagaac ttataccagc
    49321 atctggaaaa gtgggaaaat gaaacatttg tcagtcgaca tacttatcta ttcgatacgc
    49381 cggaagaagc aaggaaaaca ttcttcagca aagatatgtc taccagcttg ttcgttttcc
    49441 aaaaaaccac acctgactat ctgccaatct ataaggagac aaaagacaat aaatacgacc
    49501 ggtataacga agaaatacta gaaaacgaaa caacttttat aaaaacacat ccaggcggtc
    49561 ttttgacaat caagtggaaa aacactgggg acaaaactgt tcatatccct gttatcgtct
    49621 acgatcggac tgtgctacag caaaatggaa aaacattgac tgattatgaa gtaacagata
    49681 tcgggacccc aatcgtgaag cagcaaaaag gaatcaacga gctcacgctt cattatcaaa
    49741 cgccaatcta tttctatttc attctttctc ttactttgat tggctggttt accttgctat
    49801 gtttatttat ttatcataga tacaagcttt tacgtgctta ggcaaaaggg ataaatacat
    49861 ccgatcaaaa aactctccaa acggtataat cgtttggaga gttttatttt aatcagtttt
    49921 tttatgttat atgttatatt ttttattcgt tcacatctaa ttcgatttcc accccgtagt
    49981 gatcactgat gattggacta tcgatcccat caaaaatccg ttgatatttt ttaacctgca
    50041 ttccttcagg gacgaaaata aaatctatac gcaatttttc tgtattttgt tcccaaccat
    50101 ctattttctt ttccacagta gctgcttttc ctttttcatt cgcgacaaca tacgaatctt
    50161 gaagaagaag gcaactttct cttacagtat aataaccttg agagtctact ggattattga
    50221 aatcacctag gaaaaaaagt ggtacgcgag tttccaaaaa gtagttttcc aagtttttcc
    50281 actcaaaata aaagccactt tttttatctg tccaccaaga aaagtggcag ctcgagacaa
    50341 aaatgtcctg atcatctatc tttgttttcc caatcaagat cttgcgtgtc tgataatctt
    50401 ctttcttttg aaattgggag acggtaagga cctgactttc caatgttttt ttcgtaagca
    50461 gtgcatttcc ttcttcatat ttatcataac cgatgtggct catttcccaa ctccaaaaat
    50521 actcttttcc gtgttccttt aaaagctgaa ctaaacggta ggcaaaatta tctttacgga
    50581 taggtacttg attctttacc ggacagaact tcattagctt cgcaggttct acttcttcag
    50641 attccagtaa ttggttgatt tcttgtaaag caatcacttc ataatcttct aacaggatct
    50701 tatctgctaa ttcttgcaat tttttctctg gttctggctc aagccagcta tgcgtgttga
    50761 gtgtcatgaa tttcattggt tttctccttg tcttcatttc gaaacaaaag ggttgtgaca
    50821 aaatttttgt cacaacctct ccagcaaata gtgttctcct gctaactcct cagtaataag
    50881 ctcaatggac caggagctat tttttgtttg gctgttttta tcacttggtg cagggcagct
    50941 ttttcacgac ctctccacta aacagtattc aaactgctgc ttctcggtaa taagcccaac
    51001 caaacgaaaa ataggaggag ctatttttgt ttggctgttc ttatgacttg atgcaggaca
    51061 gctttttcac aacctctcct tacattttaa tggagccgat cactttacca gctgtcactg
    51121 tacctaattg cttgatcact acttcttcta ctttatcgtt tgtaaatacg atcatgatcg
    51181 ttggatcttt ttcttcgttt tggatcacat caagatccat ctcagctaat ttcgttcctg
    51241 ttcctacttc ttggccttct ttgacagcaa tctcaaaagc tggctgattc atttggactg
    51301 tatcgattcc catatggatc aaaacttcga taccatcttt cgtttccagc ccaattgcat
    51361 gtttgctagg gaaaatactt gtcacttttc cagcgatcgg cgcaacaact tctcttgatg
    51421 ttggaataac agcaaagccg tcacccatca ttttttgtga gaataccgga tcttttactt
    51481 cagataaagg aatcacttct ccagaagctg cggaaactag ttcttgttct atacctaagt
    51541 attgcttact acctgcttgt ccatttcctg tagaaaccat ttctggctct ggaatctctg
    51601 ctcctgattg cagcagatct tcgatatctg atttcaagac atctgctttt ggtccataaa
    51661 ctgcttggac tccattgtct ttgacgatca atcccatcgc ccctgctcgt ttccaggctt
    51721 cttcagtccc tactttttct cgatcattta cacttacgcg taaccgagtc atacaagcat
    51781 cgacatcttt gatattttct tttcctccca gcaaatgaat gatctggacc acttgctgat
    51841 ctgctgttcc tgttccgctg ttagatacaa cggtttcttc actgtcattg tcgtaatttc
    51901 cgttacgtcc cggtgtagca aagttgaatt ttttgatcaa gaaatttgct aagaaatacg
    51961 taacaacacc aaaagcgatc acacacaaca cgaagttgat aagatctcca cctagacccg
    52021 ctttgatagc taacggtgtc cgagtcagca attcgatatt cccaaatgaa tggacccgca
    52081 atggcaagat atctgccatc gcaaatgcag ccccttggat cactgaataa atgacatata
    52141 atggcacagc agcaaacata aacatgaact ccaatggttc tgttacacct gttagaaaga
    52201 cagccaacgc tgctgaaaaa tacattgatt tatatcttgc tttcttatca ggatcgacat
    52261 tacgatacat cgcaaaagcc attcccatca agatacctga agaaccaatc atttgtccta
    52321 ctttgaaacg agccggcgtc cagttatgca acacaaactc atattgcgac atatcccctg
    52381 cacctttaag attcactaaa tcagtggccc aagccaacca taacggatct tgcccaaata
    52441 cttgtgtccc cgcctgtgcg cctgataaaa tctcatacga tccgccaagc tgtgtatagt
    52501 tgataggaat cgtcagcata tgatgcaatc caaatggcaa tagtaaacgt tctaatgttc
    52561 caaataaaaa cggtgctaga atcggtgcgc tttcttgtga ttctgcaatc cataaaccaa
    52621 aattattgat tccagcctgt acgtttggcc acaccacagc aagaatcaat gccacgattg
    52681 ttgaccataa gataacaaca aacggaacaa agcgctttcc attgaaaaat gacaaagcat
    52741 ccggcaattt tctataatta tagtacttat tataagccat tgccccgaca aatccagcga
    52801 tgatccctac gaatactccc atattcaaag ctggtgcttc caatacactt gtaaaaaatc
    52861 ctttaaccat gatcttcgta ccgaacagag tgtgggtaaa tgcatcttca ttcgcaagca
    52921 tgtcacttgt gacaccaaag atagccccag tgatccgatt gattaaaata aatgagatcc
    52981 cagctgcaaa tgctccgcct gctctttctt ttgcccaact tcctcctatt gctaaagcaa
    53041 ataaaatatg aagattacca ataattgccc aaccaatatt ttcaattact ccgcccgttg
    53101 tgacaagcgg cgtccaatca ggattgatca agggaattga tttccctata ctgatcatca
    53161 acccagctgc cggcataact gctaccacaa ccattaaagc ctttccaaat ttttgccaaa
    53221 actcaaaact aaatatcttt ttcattccgt ttagctcctt tacgcaatcg gtttcgttaa
    53281 acgtattata gcgtgcgttt tcttttttgt aaatgcttta ttttttattt ttctgtctat
    53341 accattctat aaaacctata atacgtgtgt tcccttctat aattttctcc taaaaattta
    53401 tttttttaag cttttttcta tgaaatattt tcttttgtct attgacttgt gcaatcggtt
    53461 gcgtttatta tgaacgtata aaacagctca ttaggaggag aaaaatgaaa cagatcaaac
    53521 gactatttgc tattgatcca tggaaaatca gcacgacaca attagataaa aaaaatcttc
    53581 gactgcaaga atctttaaca agtattggaa acggttatat ggggatgcgc gggaactttg
    53641 aagaaactta ctcaggggac caccatcaag gtacttattt ggcgggtgtc tggtatcccg
    53701 ataagacacg tgtcggctgg tggaaaaatg gttatccaga atactttgga aaagtgatca
    53761 acgccttgaa ctttatcgcg atagatattt cgatcaacga tcagctgatc gacttggctt
    53821 ctttggaacc agaagacttt tactgggaat tagatatgaa aaatggtgta ttatctcgta
    53881 cattcacaat cactacttct actaataaag tacgcatttc cttcgaacgt tttctgagca
    53941 ttgtcaaaaa agaatcagct tatatctatt taactataga aatgcttgaa ggtagcggaa
    54001 cagtcaaact cgtatcaaaa ttggatggaa atgttcaaaa cgaagacagc aactatgatg
    54061 aacatttttg gaatgagatt gatcgtggaa ctatagaaga aatcggctat ttgacgacta
    54121 aaactattcc aaacaacttt gggattgaac aatttactgt tactgcagca atgcgccatt
    54181 tcgttaatgg aaaatcagtc atccctgact atcacgaaga tactttagca ttacatggtt
    54241 gcttgtctgc agaattatct caaggtgaga catggtcagt ggaaaaagaa attatcgttc
    54301 ttactagtag agatattcca gaagcgcagc aagcagaaaa agctgtctca gaattaacga
    54361 accagacaaa caattatatc caagcaaaag aagagcaaac agcggcttgg gcagaacgat
    54421 ggaagcttgc cgatgtggtc atcgaaggag acgaagaagc acaacaaggt attcgattca
    54481 atttgttcca actattctct acttactacg gcgaagatga acgattgaat atcggcccca
    54541 aaggattcac aggagaaaaa tacggcggag ccacttactg ggatacagaa gcgtatgctg
    54601 tccctcttta tcttgcttta gccaaacctg aagtaactaa gaatctgctg aaatatcggc
    54661 ataatcaact gccgcaagca atccacaacg ctcagcaaca aggattaaaa ggcgcgcttt
    54721 atcctatggt caccttcact ggtgtcgaat gccataacga gtgggaaatc acattcgagg
    54781 agattcaccg aaatggcgcg attgcctatg caatctacaa ttatacgaat tacaccggcg
    54841 atacggaata tttgaaaaat gaaggactgg aagttttagc agaaatcgca cgcttctggg
    54901 cagaccgtgt ccatttttca aaacgagcaa ataaatacat gatccacggt gtgaccggcc
    54961 caaacgaata tgagaacaat atcaataaca attggtatac aaatacgatc gcagcttggg
    55021 tcttgcgtta cacgcgagaa aattatttaa cttatcaaaa agaagctgct atcactatca
    55081 gcgaagaaga actagccaaa tggaaagata tcgcagagaa catgtacttc ccagttgacg
    55141 aagaattagg aatctttgtc cagcatgaca cattcttaga taaagatctc atgcctgtat
    55201 ccgatattcc cacaagcgat cttcctctga atcagcattg gtcttgggac aaaatcctta
    55261 gatcttgctt catcaagcag gcagatgtac tacaggggat ttatttcttc aatgatactt
    55321 ttacaaaaga agaaaagcaa aaaaactttg atttctatga accaatgact gtccatgagt
    55381 cttccctttc gccaagtatc cattcgattt tagcagcaga attaggaatg gaaagcaaag
    55441 ctgtagaaat gtaccagcga acagctcgct tggatttgga taattacaat aacgacacag
    55501 aagacggctt gcacatcact tccatgactg gtagctggtt gtcgattgtc caaggatttg
    55561 ctcaaatgaa aactgcccat gatcagttga gattcgcacc atttctgcca aaaacttgga
    55621 aagcttattc tttccatatc aattatcgcg gacgtttatt gttcatctca gtcacagatg
    55681 aacaagttac tttcaagtta ttagaaggtt ctcctctaga aatttacgtc tatgaacagt
    55741 cttattcttt agcggatcgt ctagaaataa cgctaagaaa ggaggaagca aatgtttaaa
    55801 ggggtattgt ttgatttaga cggtgtcatt accgatactg ctgaattcca ttatcgtgct
    55861 tggcgaaagc ttggtcagga aatcggcatt acgatcgacc acacattcaa cgaacagcta
    55921 aaaggcgtca gccgagaaga ctcactctct ttgcttttag cttatggcgg aaaagaacac
    55981 tcttttacaa aggaagaatt tgcagaatta gcgaaaagaa aaaacgatta ttatttagag
    56041 atgatccaga cgatcgaacc aaaagatgtc ttccccgggg tcgtgccttt actggattct
    56101 ttaaaagaag aaaaaatcaa gattgctctt gcttctgcaa gtaaaaacgg gccattccta
    56161 cttgaaaaaa tgggtcttac accttacttt gatgctattg ccgacccggc agaagcaaca
    56221 aacggaaaac ctgcgccaga tatcttcctc cttgcagcaa aagctgtcgg actaaaagca
    56281 gaagaatgta tcgggatcga agacgcgcaa gccggtatcc aagccatcct ctcaagtggc
    56341 gctcaaccaa ttggcgtggg acgtgctgaa gaccttggag aggagatccc gcttgtccct
    56401 gatacgactt ttcttacgat cgattacttg aaagaaaagt ggcatgacca tggataatcc
    56461 agagatctcc gtcgtaccag ttccagagac tgaaataaag aaaatcacat tgaagaacga
    56521 ctacttagaa gtcgttcttc tcaattacgg tgcccgcctg caccaaatct tcgcaccaga
    56581 caaagaagga aaatcagaaa atgttttatt gtcttacgat cgtttcgaag atgttctaac
    56641 agacaaaagc ttttttggag caactgtcgg acctgtagcc ggaaggatcc gggatgcttc
    56701 ttggggtgag catagattgg agaaaaactg cggatcacac catatccacg gtggcacgaa
    56761 aggctggtct ttccaatttt gggaagtaga agttttcaaa actccatcat caataggtgt
    56821 ggtcttttac ttaaaagatg aattttctac ctatccagga ccaatcactg ctacgatcac
    56881 ttaccgttta acaaaaaacg aattagagat gacaacctct gctagtagcc ttgttgaaac
    56941 catctgcaat ccgaccaacc atgcctactt caacctttca ggaaatggaa caagagacat
    57001 ctatgaacat cagttaacgg tctttttaga tggtgtgctt gaattagatc aagaaaaact
    57061 gcctactgga aattggacaa aaaaagaaaa actgccaatc gactttagaa aatccccaac
    57121 actgcaagag atccttgcat gttatccaga tggactagat gatgtatttc ttttgcatca
    57181 tcctaggctt tccaaaactt ccttacaatt attcgagaag cattctggtc gccaaatgac
    57241 tatagcaact tctaataaaa gtatggtatt attttctacg actggattcg aagctgattt
    57301 ctctgtcaat ggaaaacaga tgcattcaaa ctacggatta gcaatcgaac cgcaagaaat
    57361 ccctgatatc gttcatttcc ccaaatttgg atcgatcaac ctccatcctg gtcaagaacg
    57421 gatcagtcag acgatttatc ggttctctgc acaataacaa gagaaaggtg tttttatcat
    57481 ggctattacc gtaaaagatg tggcgaaaaa agccggtgtt gccacctcga ccgtctctcg
    57541 tgtcatcaac gatcatccta gtatttccga gacaacaaag aagaaagtcc gaaaaattat
    57601 ggatgaacta ggttatgttc ctaacatgac tgcccgcaat ctaggaaaac gcatttccag
    57661 tgccatcggc gtaatcttac cccctcttga ttcaaaagag cggatcggta acccatttta
    57721 tcttgagatc atggaagcaa tcaacgaaga agcgcggaat tatgatatga ctacagcaat
    57781 cgctactgct aaaaattttg aattgctgtt agagaacgtc cagcgtatgc atttacaaaa
    57841 acaagtagat ggttttattc tagtgtattc agatagtcaa gatactgtca ttgattattt
    57901 ataccaaaac cacatccctt tcactttgat cggacagcct tatcatcatg agaacgaaat
    57961 cgtttatgta gataatgata accagcttct aggtaaacaa gcaacagaat ttttgatcca
    58021 gaatggacat aagaatatcc tgtttgtgac aaacacgact catgaaagtt tgtatttcga
    58081 acgatatttc ggttatcaaa aagcaatgat gatggctggt cttcctgcgt tatccagtgt
    58141 agtactagag catccggagg attatctgtc ctttgagaaa acgttgaaag aaaacgaagc
    58201 cacagcattg gtggtcattg acgatatctt cgcccttcgc acgatgcagt tggcgcaaat
    58261 gtatggctat gtcattccag agacactctc cgtcattagc ttcaacaact cgatcttctc
    58321 aacattaaca cacccttacc ttacaagtat cgatatcgat atctccgaat taggacgtgt
    58381 cgctatgcaa aagctgcgcg aattgatcca tgaagaattg agcagtggcg tacgtttggt
    58441 catccctcat cgcttgatca aaagagagac agtcgttcct ttagaaaacc catactaaat
    58501 agctgactca ctaaatacgc tgaccattta tcctatggtc agctttttat gtaaaagaag
    58561 atactacttc taacacattg tttatctgta aaaaagagcg tgggacaaaa gtaaagaaca
    58621 cttttgtctc acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa
    58681 taagctgaaa ttcacaaaaa tttaaaaagc aattttcttg agtttcttct tatttcttgg
    58741 agttaaacgc ttctgtccca gcctcttttt tccttccttc aattttttac acgtcgacga
    58801 ttcaataaaa aaccgcctaa tattgtaaag acaggtgcaa gaatcgagaa aaaggcgaat
    58861 ggcaagtaat gcaacgcgct aactttcatc gttcccataa tgaatgtgcc gctgactccc
    58921 cacggtacga gagaattgac ggtcgcacct gaatccgcta gtgttcgtgt caaataggtt
    58981 tttgataagc caacgtcatc aaaagaacgc ttgaatgttt ctcctggaag aatgatggac
    59041 agatactgtt ctccaacgat cagattgatt ccgatacagc tcaaggcagt aaacccgact
    59101 aaacgagaag gtcggtccat cttttctttt aattcttgaa cgatggtatc aacgatcaga
    59161 tatttgatca gtaacccacc taatgccaat gcaagtaaaa tcaaactagc agaacctaac
    59221 atactcatga tcccgcctcg agaaagcagt tcatctagct ttggatcagg tgtatttgcg
    59281 acataaccat tcatcaagat gtctgctgct tttccgaccg tcaaactttt ctcatggata
    59341 aaagaaagaa cgagagcagc tgtcgatccc gctagtaatg tagggatagc cggaattttt
    59401 ttgattgccc ccccaaataa aataactagt ggaatcaatg tccaaggaga gatccaaaag
    59461 ctcgctttca tgttttggat catttcattg atactagcta gatcggctga atgactgtta
    59521 tgtcctaata tcgtataaaa aatcaacgaa aggacgaatg ctgggaaatc cgtataacgc
    59581 ataccagcga tatgttcgaa tagattaact cctccaatac ccgctgccaa gttggtcgta
    59641 tctgataaag gcgagcagtt attccctaaa aaggcaccgg aaacgactgc gcctgtagtc
    59701 attgcatcat tgaatccaag taaatgaccg atccccaaaa aagcaattcc aatcgtcgaa
    59761 atcgttgtaa atgaactgcc gacagtcact ccgacaattg cacaaacaag aaatgctgtc
    59821 ggtaaaaaga aacgcacaga aacaagttta aatccataaa ccataatcgt agggatggtt
    59881 ccagataaaa tccatgaagc aactaagaca ccaatcaaaa gaaaaatcag gattggaatg
    59941 atccctggag tgattccttt gatgatcccg tcatggatct catcccatgt gaacttttta
    60001 aatctgccat aaaacaacaa acacatgaaa gctgcaagga tcgggatatg tggcgagagc
    60061 tggaatccga tgatcagtac tcctaggagt gccaacaaca cgatcaatac agcgatactt
    60121 tcttttaaag aaatattttt attcatcgtc gatctcctat ttcaaatgaa aaggccctgc
    60181 catgaaaaaa ctattcactt ggcaggacct cctactaaat cagcgacaaa acgtcggctg
    60241 aaagacttat ttttttattt ttcttctaaa cttttttcta cctcaatccc ccaagaatct
    60301 ttcttgaagt gattgatgat caatggaata acgaacatga ccactgtgat agctgctact
    60361 aataatgcat cactcaatgt cgctgtacct aatgtagcaa atacgacaac gatgatagag
    60421 aagatcagca tgcagctgac tacccaagct aatccgtttc cgtttttacc aattcggtaa
    60481 ggacgttcga attctggatg tttcttacgc attttaagca atgaaacagc aatcaaaatg
    60541 tacacgatac aataaataac agttgtagca tttgtaagtg tcaagaatac agcacttacg
    60601 tcatccatta caccataaag caaagcaaat aatgaaataa cgattgattg tgttagaacg
    60661 acatttctag atacgccgta tttgttttct ttatggaatc cgaattttgg tggaaggaat
    60721 ccttcacgag ctacttggat gattgttttt gatggtccag taacccaagc tgataattgt
    60781 aaaagcacac caataaatac catgaagctg aagatatttc cgatcacttc tggtaagcct
    60841 aggatttgac agtcaatcaa gataggctgc gtgatatttg ctaattccat ttttccatct
    60901 ggtacgacat ttgctacaag catcgcattg atgacattca ataaaactaa tccgatcaaa
    60961 gcgataaata cgccttttgt ataatttttt gttgcgtctt tcaaacgagg catgtaaaca
    61021 gaactcattt cgatcccaac aaaaataaat gtgataccag ctaagtattt caatgaatca
    61081 atatgttcca agtcagggaa agcttttgac catgaaaagt cacctagata gccgtttgag
    61141 actagtccga ctttgaaggc tgccaaaaca cctaaaacga acatgatgac tactgggata
    61201 tataccccta gccatacacc gatgttcccg ccgacttttg ccatatcgaa tttcaagttc
    61261 aagatcgtga tgatccagta gataactaaa atacaaccta aaacgaacca gtgattattg
    61321 ccaagttcta cattaccaaa tgtgtttcct aacaatggtc ctaaagtaga agcgaccatt
    61381 accatacctg ggaacatttg cacccataat agccatgcaa cgacaaatcc ccatttgctg
    61441 cccagtgctg tttttaccca taactgagga ccgccttctt gaggaagcat cgtggaaagc
    61501 tcaccggaaa ccattgatat cggaccggca aaaaacaaaa ctgcaaaaat tgaataaaaa
    61561 atcaatgtcc aaccgactgc ggctaacgta ggaatactcc gaaccgttgc acacagtgcc
    61621 attgtcagac cgataaaggt cccaagaccc attttactta cttcagattt actcaccgtt
    61681 gacactctcc ttgatttttt ggataaaata acggtgtctt tgaagtagtt tcagcaataa
    61741 acgaaacaat tcagcgaata tttgagggga ttctttgagt ttattgcttg aagggtttct
    61801 tcaaagacaa cctcaaaaca aagggatcga agagcttagg tctccccttg ctcttcagat
    61861 ccaaacatgc gtcagaaaca gttagtattc aagctgtttt ctaacatgat taccttgctt
    61921 attttgcttc gcttgccaat aattggtctg cgtagatttt ttccaatttt tcttgaagag
    61981 ctgctttgat tttttcagca tattcttcaa agtgttcttc tttgttcatg tatggtgtca
    62041 ttacgctggc acgcaataca gttacttttc cggcacggtt ccattcttca tctgagaatc
    62101 ctagttggtt cacaaattgt aatgggctgt tgccatagtc tgggatagca aagtcagtat
    62161 gtgaagttaa gaactcatta ccgtaaatgc ttcctttcac gtatgaagaa taatcatata
    62221 cgtcatggtt caatttattc attgcaacta agtcatcgtt gcctttttct ttgaatacat
    62281 agtctaccat attgaaatct ggataagtta atggatgaac ttcgatttct ttgtctccta
    62341 ctttaaatga caagtcattc aagaagttgt agaaacgatg tgcaccttcg attgatgcac
    62401 ccattaattt accatatcct gtgacattca aaggtaagac atggtgtgct gcccaaacgc
    62461 tggctgctgt tgcccctgct tttgaacctt ccaagatata agccccaagt aatgctggga
    62521 tatctgcgcc tttttcaaat acatatgtcg caaagtaaga gataacgtct ctcatgcgga
    62581 tatctttgat gacgatacca ccggcagaat atggaacata gcccatttta tgtgggtcaa
    62641 tcgttacaga ttctgcttct tcgattgctt tatatgcact gtgtacttct tctaagatat
    62701 aatctttgtt ttctgtaaag acattgtatt tgtaatgaac atcttttaaa tcttcaaatg
    62761 gaatgaagtt gttgtcttcg tctaagaaaa tcgcacggcc gtatccgcca taagcagcat
    62821 ctacgtgtaa gtagaagtaa ataccgtctt tttctaatac gcgacgcaat gcaacgattt
    62881 tatcgatacc gtcgattgct ccttcttctg ttgatcctac aacaccgact acacctagga
    62941 ttggtgtttt ttcagctgct agaccacgaa cgattttttc aagttcgttg atgtccatgc
    63001 gatagttgtg gtcaactggc actggaatca cttggtctaa accgataccg atgatgtcgg
    63061 cagcttttag ccatgaatag tgtttagttt gtggaaccaa ccattttcct aatttttcta
    63121 aatgttttcc gctacgtgct gagtgagctt tgatttcgtc gattttttct gggacgctgt
    63181 ctaacagatt catgatttct tctgttgaca agttcattaa ttcccaatcg ctttttccag
    63241 caactagttc aggtgtcact tctttcattg caagcggcaa tgatttgatg ttgcgggcat
    63301 accaaagtcc ttctaagttt gctaaagaac catcagcaac gatgtggccc cagccatctt
    63361 tatagctcat taattttgca aattccattc ctacttcttc ttccatttgg cttgttgcag
    63421 gagaagattc ataggcaacg ttattaccat tccatagcat agcaaaattg tacgctagta
    63481 aagatggcat caatgtttca gagttcatat gaccccagta acgtccggca ttatgccaag
    63541 gaacggaatg ggtacgcatc cgcgctgaaa tttctgatag aacatccttt gttttattca
    63601 cagtgtgttc aaaactagca ctgctttttt cttctggcgt aataataggc atgtcttgag
    63661 gcatgtagtt ttgacgccag cctaaatgtt catccaccaa ttcattcaac aaagctttat
    63721 agatttggcc gttctcagct ttgtccccaa tgaatagggc atttaggttt agatctttcg
    63781 acaatgattc actcatagtg aaaccctcct aaaaaaatat ttaaattttg tcgagcccta
    63841 cattacacct gttcttctat tctgtaaact aagttttggc ctgattttta atcatatttt
    63901 aatatgtatc aattatccga attgttcaca cttttgaaat aattaaaaaa aacgagggaa
    63961 tttacaaatg taaactccct cgcaaagatt gtattaacga caaccagcgt tctattttag
    64021 gatgggtttc aaaattggaa tgttgtaata gtatttccct ttttcaaggt aaaaacttac
    64081 taaattctaa tcaattactt tggccaaaaa gtaatttttc ttaccttttc gaataaccac
    64141 aaacttacca tcgaattcat cggatggatt tatgacaaaa tttaaatcgg taacgcggtc
    64201 accgttaata cttatagctc cgtttgaaac atcttcacgt gcttgacgtt tagatggttc
    64261 aatttttgtg gaaacaagca gttccacgat attttcaggt gtgcttgaaa tttcaacgtt
    64321 cggcatttta ccgaatcctt gcgcgatttc ttccgcattt agttctttaa tatttccaga
    64381 gaacaatgct tgcgttattt tttgcgcttc tttcaagtct tcttcactat gcacaaatct
    64441 tgtaacttct tctgccaaac ggcgttgtgc ttcacgtttc tcaggttctg tctctacttt
    64501 tttcgctaag tcttcgattt cttcttgaga caagaaagta aagaatttca agtatttcac
    64561 tacatcgcga tcatcttgat tcaaccagaa ttggtagaac tcaaatggtg aagttttctt
    64621 cggatcaagc caaacggcac cgcctgcagt ttttccgaat ttcgttccgt cagccttcag
    64681 catcaatggg atcgttaaac cgaacgcttc tgcttctggt ccttctaatt ttcggattag
    64741 gtctaatcca gctgtgatat ttccccattg gtctgctcca ccgatttgca attgcacatc
    64801 gtatgtttta tgcagatgca aaaagtcgat agattgcagg atttggtaag taaactctgt
    64861 aaatgagatt cctacttcca aacggctggc aacgatatct tttgctaaca tcgtgttgat
    64921 gttgaagttt ttaccgtagt ctctcaaaaa ttcaagtaaa gagatttttg acaaccagtc
    64981 gtagttgttc acaaatgtga tatttgcatc tttaccaaac aattttctca tttgattgga
    65041 aagtgcgtcc acgttatgtt gcacttgttc catcgtttgc aacacacgtt ctgttttgcg
    65101 gccgcttggg tcgccgatcg ttcctgttcc gccgccaatc agaatatatg gatgatggcc
    65161 tgccaattgg aatcttttca tcatcataaa tggaatcaaa tgtccgatat gcatcgaatc
    65221 accagttgga tcaacgccgc aataaagtga aatgctcttt tcttcaacga gctcgcgaag
    65281 tctttcttcg tttgtttgct gattaatggc gtcgcgccaa gttaattcat caataatatt
    65341 cattttactg acctccgtgt agttttttta tgaaagcagg aacctgctag catgtgtaat
    65401 taattatttc ttcaggatag gataggaaat aaaaaaagtc ccttggcata taagccaagg
    65461 gacgaaatct cgcggtacca cccaatttgt atgtctagat atccaacata cctctcgaac
    65521 atttaacgct gtcgcgtggc aatcactgcc aaagactcct gaaatgtaat tcgctttaaa
    65581 gcatgtactg gtttgcagcg accaccagct ttctgaaaca ttggctttaa caactacttc
    65641 gtttcgatct tcgtcttgtt attattaata tgtgtctatc atagagcgca actttttctt
    65701 tgtcaacaga aaaaggatat tttttttaaa ttcctcattt tttctttttt gaatccgctc
    65761 taattccgaa cattttattt tcaattattg ttaaaagaaa taactttttc tgtatttttt
    65821 ctgcaattta tcgagaagtc actttacttt gcctcttatt ctttcttcgt tacaataagg
    65881 aatgggacaa gtaaaaaaat gaaaaagcaa gggacgaggt atatggaaaa aaagcaaaaa
    65941 attattttag gagccacttc tgctttaact atcgttattt taattctaag tttgtttttt
    66001 gtcatccgat catctacaaa aaaagaacca atcattcctg aaaaaaaaat aacagaaaaa
    66061 gcaaaagaac cgacagatga taagcaacaa ctagttactc aagcaaaaaa tctggctcaa
    66121 agctacgatt atgaccaagc gattgcgtta ttggaaaaag atagtaagaa cggatctact
    66181 gaaacacaac agcttcttca aacactaaaa aaggagaaag aacaactgat cgactggtct
    66241 gatcctactc agatctctca tgtctttttc cacagcttga tcgtggaccc gcaaaaagcc
    66301 ttccactctc aacaggcaca aggatacaaa gattatatgg tgactgttga agaattcaac
    66361 cgttcgatcg aacaacttta tcaaaatgat tttgttttag ttaatttgaa tgatttgatc
    66421 caaaaagacg aacaaggaaa tctttccttt aacgggcttg cgctacctga aggaaaaaaa
    66481 ccattggttc tttcacaaga tgatgtcagc tattatgaat atatggataa ttccggtttt
    66541 cctagccgat tggtcgtatc aaataacaat gaaatcaaaa atgtctataa agagaaagat
    66601 aaagaagaaa tcggtgactt tgacatggtt cctctgatcg atgcctttgt caagaaacat
    66661 cctgattttt cttatcgagg cgcaaaaggt accttggccc tgacaggtta caacggagtt
    66721 ttaggttatc gaacatcaaa atctcaatat ggagacaatg aaaaaacaaa aaaagagatt
    66781 aaagaagcta aaaaagtggc ggaacagttg aagaaagacg gctggagctt tgcttcccat
    66841 acatggggtc acttgaatat gactcaagct tcactagaag atgtaaaaaa agacaatgaa
    66901 ttgtggcagc aagaagttgc acctatccta ggaaaaacaa atattctgat ttatccattt
    66961 ggtgcagaca tcagcgactg gcagccttat tcagcagaaa atcaaaaatt tgcttacttg
    67021 aagagtcaag gtttcgatat tttctgtaat gtcgatgctt ctacaccagc ttggggacaa
    67081 ttaggtacgg atttctatcg aaatgctcgg atcaatatcg atggcattcg ttttcaatct
    67141 gatttagacg gaaaaaatcc tattcttgat ccattcatca atgtccatga tgtctatgac
    67201 aaagaagcac gcgaatctgc ttgattttac gtcatttatg aaccaaaaaa gccgaactga
    67261 cattttatcg tcagtttcgg cttttttatg ctttatttct tcttcggtgc gattcccttg
    67321 atcaggactt ctgtccattc tgctgtatat ggaagcagtt ttgcgtatat ctccggctta
    67381 gaaattcctt ctaccattgc ttgaaaatag aggatcaaga actcatccga atatttcaaa
    67441 tccacttttc cttctttccg ccctcgatgg aaaagatcaa gcatgatact gaaactttct
    67501 tgcgtatacg catccatcgc gtcagaaaat tctttttttt ctttttttgt atagtatgtc
    67561 atcaaatcga tataaaattg tttgttcact cgattgagat aacggatttt gttttcactc
    67621 atggcaatca gtgtttcttc aaatggaaga ttttccgcaa tcaacgcttt cgcttcttgc
    67681 cctaaatcat tcataaatgc aaaaaatact tcataaatca gcccttcctt gctgccaaaa
    67741 tatttaaaaa tcgtcgcttt acttacctga gcgttctcag ctaccttatc cattgtcact
    67801 ccagcggttc ctatgtctgt gttcatcaag tcaaaagctg cttgtaaaat ctctttcttt
    67861 ttctcttgtg ctctcttttc aaaaccgttc atttgtagag cctcccgtaa ttttaaactt
    67921 ttataatata tatagttcaa atttattctg aggtttatta taactatcta ttgagaaagt
    67981 atcaagctag caattccttg tttatgaatt cattgacaga aatttataaa aagaatatta
    68041 tgtactaaaa taataaaaaa agttttataa aaaggtataa aaccttttta ttaaactatt
    68101 taatcttgtt tagtatatat ttttagaaaa aggagtgggg tttttatggc agaaatcgtc
    68161 aaagtcacac atttgaaaaa gagctttggt cgtttcgaag ctttaaaaga tgtctctttc
    68221 accgtacatt caggtgaagt cgttggattt atcggaccaa atggttctgg aaaatccacg
    68281 acgattcgga cacttttagg gattataaaa aaagacggcg gaacggcaac gatttttggg
    68341 caagatgtat gggaagatag tttatctatc catgaacgtc tttcttatgt tccaggcgat
    68401 atctctttgt ggggaaattt gactggagga gcgatcatcg atctcttcat gaagcttcat
    68461 ggaaaaggga gtgctcaaaa aaaagatgaa ctgattcaac gtttctctct tgatcctaag
    68521 aaaaaagcaa aaaactattc aaaaggaaat cgccaaaaag tgggcttgat tgctgctttg
    68581 gctgttgatt cggatctcta tttatttgat gagcctactt ctggtttaga tcctttgatg
    68641 gaaacgattt tccaagaaga agttgaaaaa ttgaaagaac agggcaaatc catcctactt
    68701 tcttctcata ttctcagtga agtcgagcga ctagcggata aagttgtgat catacgcgaa
    68761 ggaacactcg atgaagaagg aacactcgat gaattgcgtc atttgactcg ttcgaccatc
    68821 actatagaaa cagaagcaga gaatagtcac ttagcacaat tgaacggtgt ccatgacttt
    68881 gtgcaaaaag gtcacctcgc tcaatttgct gctgataacg aagctttcga tgtgatttta
    68941 gctgaagcgt ccaaattagg tgtgaaaaaa tttgaatcta ttccaccgac tcttgaggat
    69001 ttattcatga gacattatga aggatgagga ggaagcgaaa tgactgataa attttcacgc
    69061 tggtccaccc ttttttctca aaaccttagc cgtgactgga aaaagatcct gatatggcta
    69121 gtcggtgtca ctgctttttc tggtggtttt gtccctgcgt ttgaagaatt gacttccgga
    69181 caaggattag ctggattata cgaaaccttg caaaacccgg caatgattgc aatggtcgga
    69241 ccaactccag cttcgaatgc tgctgagtat actttaggag cgatgtatgc aaatgaaatg
    69301 ttgctttttt gcagtttgtt tgctgctgtg atctctgttt tacacgtggt gagccaaacg
    69361 agaaaaaaag aagaacttgg tctgattgaa cttattcgtt cctttcgagt cggacgtcaa
    69421 gcaaactctt tagctgtcat cgctgaaagt attctgatca atttgctttt agcaatatcg
    69481 atcagttgta cgatgatttt tttccaagcg gattcgatca ctgcagaagg tgcttggctt
    69541 tttgggctat ctgtaggtag tatggggatt ttggggagtg ccgttgcact gtttgctgca
    69601 caactgatgc caagttcagc cagttcgaat ggtctgtctt tagcgttttt aggtggactt
    69661 taccttctac gagcaataac agatgtagct gattcctccc tttcgatgtg gaatccttta
    69721 ggctggtctt atttgaccta tccatttaca actaacaact ggattccttt gctttatttg
    69781 tttttgttca gtctaatctt gataatcagt tcatttgttt tagaggaaca tcgagatttg
    69841 aacaccggct atatccccga acgtgaagga aaaccgtatg ctaaacgttc tcttttatcc
    69901 ttgcgtggtt tattattcta tctaaataaa gggatgacaa tcagttggct tatcactttt
    69961 ggtttgatgg gggcggcata cggctctatc tacgggaata tgcaacagtt tttagaaagt
    70021 aacgacttaa tgaaacagat gtttatccaa tctggcgtct caattgaaaa aaactttaca
    70081 agcacgatca tggtcgtctt gatttgtcta gctgctattt taccaattgc tagcatcaat
    70141 cgtttattta cagaagaaac ccacggacgt atgaatcagc tgttcgcaac aaaaatttct
    70201 aggaaccaac tttattggac caatatgtta ctagctattc tatttgctat attggcaatc
    70261 ctgattagtt ctggtgcact agggctttct gctttggctt cgatgaagga tgcgaaagac
    70321 atggatctat tgatgtttct taaagccggg ttcaatttcc tgcctgccgt tttagtgttt
    70381 atcggaatta gtggctttct attcggatgg cttcctcgaa tcggtaaact tgcttatatc
    70441 tacttagctt actcctttgc actcaattac tttggcggaa ttttggattt accagaatgg
    70501 ttttccaaaa cagctgtccc tagctgggtt ccacggatgc caaacgattc ttttgatctt
    70561 tccgtgttcc ttacgttatc atgtatcagc cttgcactgt tcgtccttgg ttctattggt
    70621 tataggcgaa gagacttact agaaggataa taaaaaagca tgtacaattt catgctagcc
    70681 tccaaatctg ggtcaaaaat ccaacatttg gaggtcattt ttttatttac aagtcttcta
    70741 actgctcttt atcaatgatc cagacttctc gattctttct ttttacataa ccattctcct
    70801 ctaataattt aaattttcta gataaagttt cgggggtcgt accgataaat gcagcaagtt
    70861 ctttcatttt cattggcagg aaaaagtgat ccttccctgt cgctttagct aagtcaagca
    70921 gatagacagc gactcgttct tctacttttt ccatcatcaa aaaagttgtc tgctgctgta
    70981 cttttgttaa tttctcaacg ttgattgcta aaagtttcag actaagggcg ggataatgca
    71041 gtaagagttc cgagaaatct ttttgtctca atatgcaaat ttccgttttt tctagtgctt
    71101 cgccaaataa agactcattt ggaacgccta gcaactggct ctctccctca tatccgcccg
    71161 gctctattac tcgtaaaagc tgttcctttc cgctagcaga taattgatac actttcatac
    71221 tgccggaggc cacgatcact aattgaggtt ctccattcgg cgcaagaatc tgttctcctt
    71281 tttccacata gtgatgtttg acaagtgcgt gtactttttc ttgatcttgc tgtactaagt
    71341 gattgaacaa aggaacaaat gaaacacata aatgatcatg actcataatc tctcctcctt
    71401 ctaaacagct atttctaata aagaaacata acttccctta ttccaactga taattttctt
    71461 ttatcatagc ataaacgtca agcgaaccag ataccagcaa atagagtgga tttctttttg
    71521 tcccttgctt tattttcctt cttttgagac cttaagtaat tgattcctat caatttttta
    71581 aatatttact ttttgaataa tcaaaaacaa accttcactc gcaagccgag agtaaggttt
    71641 gtttttcgca ttgcttattt cgtgttgtct attgaaattt ttccgcacct agcttttgat
    71701 atagtggtgc tagttcttgt aaggtttcag cggttatttg ctcaacgtgt tcgatttctt
    71761 gcggatagaa gaatagttta cccatttgaa aggttcggtc tctcatcgct tttttcaact
    71821 cttcttgttt ctttgtatcg gacaaatagt cagacaaagc taagtggtcg tcaagttcat
    71881 gttctggttg cggccatatg taataatcct tgatatcgac tgttttgctc cactctttca
    71941 gtatcgcaag caactggtta tacgctgcaa tgctaccata tcgttcttcg cttttataat
    72001 gttggtacat caaatagatt tggtattgtt tttgattcaa caaaactgct agacaggcat
    72061 tctcgtcttg acgagattcg cttcggtacg cgctccaaaa atgactgcgt aaattccagc
    72121 cattcgtcca gctttcgatt ttaggtttgc tcatgccgta catatcaggc aaaagtgcag
    72181 ctgtctggag ctgaatctct ttccattttt gccagtgttc tttatattct ttcttgattt
    72241 gttcaatctt atctgttgga tggctctctt tgagctgttt gaatgcgtag attggtcgat
    72301 caaacaactg ataatctgat tttccaagtt ccattgtttc gcctctttcc gttatctttt
    72361 gtattctacc tgaattttgc gatatggaca aatagaggtt gtgaaaaagc tgttctgcat
    72421 caagtcataa gaacagccaa acaaaaaact gcgatgagca tcaccgcagt tttattgaac
    72481 ttaaggttga ttgatcacat ctaaaagcgt tgaaaataaa atggcactag aagcagctcc
    72541 tgggtcgata tgtccgattg cacgctctcc tagataggaa gctcgtcctt ttttagctac
    72601 caagactttg gtgtgttctt ttgcctggtc aatgatttct tttgttaaat tccctgcctt
    72661 caatgcctct gtgactggca gccaaacatc taacatcgtt ttatcgtcag cttctgcctt
    72721 tcctcggctt tgaatacccg ctgttccctg ctcgatcact tcgcctaatt tttcttgaga
    72781 atcaatagaa tcgacctctt ttgtcgcttt catcatgttc atgaatgcag atccgtataa
    72841 cggaccagaa gccccaccga ctttcgatat catcgccata gagaatactt tgaatgtatc
    72901 gctgattgtt tcaggatgat cggcttgaaa agcttcttca taagctgaaa cccctcttcc
    72961 catgttattt ccatggtctc catcgccaat cggggtatct agatcactga gatattgttt
    73021 gttctgattg attgcctctg caaattgcgt gagccattct tggatttctt gaacggttag
    73081 tttcatatta tcaccctttt atcttgagat tttttaccat gaaatcgtct gtacattgct
    73141 ttctaaagaa tctttccatt gtgtctccgt caagtcgatc agtgttagag aaagaccttg
    73201 catatctagt gaggtcataa aattaccgac ttttcggaaa actacattga cgcctctttc
    73261 ttccaacaga gctaaaacat cattcatgaa cacgaactgt tccatcaaag gcgtcccgcc
    73321 cattccgttg actagtacac ctgcttcttt tggtaaattc gagtaatcat ctaaaatctt
    73381 agtaacaagt tcctttgcca gtactttaga aggctgcatc ttttctcgac gatagcctgg
    73441 ctcaccgtgg ataccaacac catactcgat ctcatcttct cctagttcga atcctggttt
    73501 ccctacttct ggtacagttg ctgctcgaag cgctagaccg atcgtcttag ttgcctgtac
    73561 gaccttttct cccagttctt tcaactcagc tagggaagca ccgtttcttg ctgcatcgcc
    73621 cacgattttg tgtacaagga cagtacctgc aactccgcgt tttccagcag tatacgtact
    73681 attttcaacg gcgatatcat catctacgat cacactttct acttcaatat cgtccatagc
    73741 agctaattcc tttgccatat cgaagttcaa tgcatcccct gtataattct taacgatcag
    73801 caaaactcct tttccactat cggcttcctt aatagccgtc tgaatctgat ctggagttgg
    73861 agaagtaaac acatcaccaa gcaccgctgc acttaacatc ccttccccta caaacccggc
    73921 atgggatggt tcatgtccgc ttcctccacc agaaaccaaa ccaacttgtt ccgctttctg
    73981 attcttggct acaacacggg aagattctac acgatgaaca agttctggat agctttttac
    74041 taatccttcc agcatttctt cgacaatatt gcttggatca ttcatgattt ttttcaattt
    74101 attcccatcc tttctttccg gcattttgtg cttctgttaa gatttgctga gtatcatctg
    74161 ttataccggc agtgatggct gctgcaaaag ctccttccac taaaggcgca tccaccagat
    74221 gataacgttg ctgctgctct tcttccaaca tgtcttttgc cagttccgag ttcaataccg
    74281 cgctaccgat atccgcaaaa acaaaataac tagctgcatc gcttgattca ttgactgctt
    74341 ctacgatttt catcgggtct gatccgatct cgccatttat tccgccgaga gaaaaaattt
    74401 gcacctcttc ggatttttgc atctgctcaa tcatttcttt aataccatct gttacttttt
    74461 gactatgaga aataagcaaa atactttttt tcacaagaat cttcctttct tttacatagt
    74521 tgctaacgat tggtttcgct ttcattaatg aacaattcaa gtatataata aatttctaat
    74581 tttgggaaaa tatgtgtagt gcttcttgaa gtttgttata ctttaattaa aagagaggag
    74641 tgatcgaatg attacaacaa caacgaacag tgtagaggga aaagccgtag tagcttataa
    74701 agggatcgtt tttggtgagg tcattactgg gatccatgca tttaaagact tggaggcggg
    74761 gttgcgaaat atctttggcg gccgctcaaa aagctatgaa aacgaactaa tgggtgcaag
    74821 agaagaagca cttgccgaaa tggccgaacg tgcaaaagca ttaggagctg atgcgatcat
    74881 tggcgtaaaa atggactatg aagtattagg cagcgacaat ggcatgctga tggtcacatg
    74941 tagtggaaca gctgtctcca cgagataagt aggggacatc tgttttaata actaaagaga
    75001 gatgggacat gtagtggcac tcaagaatta gatttttcag tctaacttcg aggtactcta
    75061 ccttcccatc ctctcttttt tatttctttt tgcggatgat tccgtaagct gctgcgacta
    75121 acacacccgc ccctgctaag gaataactga cagaagctgt tttttcattt gtttttggca
    75181 aagtctgact tgttgatttg gatggctctg tcgtttgctg aactgtttct gtcgtgcttc
    75241 cagaggtcac tgatttttct cctgccgaat gcaaaatatc ttttattcgt tggaaactag
    75301 ctgctaagtc agcttttttt gcttcaaaat cattagcaac tgtttgtgct tcgctgatct
    75361 ttccgtggat tgcttgactg gccgctgtga tatccgcttg agtttgactt agctttccag
    75421 aagctgtttg agcaacctga tttaattgct gattgaattc ttttgcttgt tggatcttcc
    75481 cgtcaagatc tgtttggaca gcttccgctt ttgctttcgc ttcggcaagc tttttctcaa
    75541 gttgtgcacg gtcatttccc actttatttt taagatcagc taaatcttga tcgattgctg
    75601 cttggtcttc tttcaatttg ttttttgcag cttctaatgc ttcttcgagt tcttttcttt
    75661 tattttccaa gtcttgcaaa tgatcgattt ggtcagaaga ggtagaacta tttattgatg
    75721 tatcttctga agatgaaatc gtttctcctg aattatctgt cggtacattg gaagtcattt
    75781 ctgtttccga ggcaccgttt tcagcaccag aagagcttat ggttgttgaa ggttctgttt
    75841 gagcaggttc agaagtttcc gcaaaagctg tctgtcccaa taagaaaata ctggaaacag
    75901 caattggcca gattaacggc ttcattcttt ttttcatcac ttttcccatc cttactactt
    75961 tttaactaat ttcttattat aagcaaaaat gtttggaaga accataaaca caacaggctg
    76021 tttgtctaaa aaacggtgca tcttttattt ttttgtacgt tccgggcttt tccatgtccc
    76081 gcttccataa cctaaaatcg ttttgactgc tggaatgaaa gtcgtcacga tcgttatcgc
    76141 gttcactatc cagaacaaaa gcatatatag tggtgcgaaa agaaggtatt tcaattttct
    76201 tcgtcgatca tctacaatca gcgaagctag caactggaaa aatcctgcga ccatttcaaa
    76261 gcagatgaac acaaaactga atgtaaaagt aatataaatc tgttcgtagt ttccttgata
    76321 tacataatgc ccgattaatc cagcaaaaag aactacggaa atacaaaaga atattgacca
    76381 gacaatactc aatgtttgat caatgaagat gatcgttctt ccaatatgtt taaaaggatg
    76441 gagcatcact tttttgaaat tcgtcagcca gacttctgtt ccaccttttg cccaacgttt
    76501 tctgtgtcga tatagcatct tcaacgtcac aggtacttcc atgaaaaaga taatctcagg
    76561 agcaaaaaca gataaccagt catttaactg atgatcccaa gcaatactga tgtcttctgt
    76621 cgctcgatct tgtctgaatc cgcccacatc gatcaaggct tcttttcgat acatcgtatt
    76681 tgctccactg tacgcataaa gaccaccgaa aacagctgac tgtgttcgtt taatgatgcc
    76741 cacgatactt gagaattcaa ccgtttgaga ttttgcaatc aatttggtac gattttggac
    76801 atccatattt gcagtgaccg cagcaatatg tcttgcacca gggcgaatga aataattcac
    76861 atacctaatc agtgcatctg gctccggtac cgtgtctgca tcattgctta aaatcaattt
    76921 cccttttgca aaggcaagtc cgatattaaa cgcgtgggct tttcctttat ttttttcgat
    76981 ccgaaccaca cgaagattag cgtatttttt catcagtcta gctaatattt ctggtgtttg
    77041 gtccgttgaa ccatcgtctg tcactaatac ctcatagttg tgataattca atttcgtcat
    77101 caaatactcg attgtatatt cgatcacaat ttcttcatta tgggctggca ccatgatcgt
    77161 gatgaacggt tcgacactca agggaacatc tacccattct ttttgcttat gtttgtataa
    77221 aaacacataa caccagacac caataaacca tacaaatccg cctaaaatcg gataagaaac
    77281 gagaaaaaaa tacataatag acaaacaagt atctaagaat aaattacctg tatgggtgat
    77341 tgagatcatt tcagttccac cccattttct ttatacaaat ctgcaatgaa tgtcgtatct
    77401 agatttttct cttcggagac agaataaaaa cggaccgttt ctctctcttc ttttgttcca
    77461 aaacgttccg tatacacttc ttcaagtaat tcttgtcttt ttttcaattt ttcatcttca
    77521 tattcaaaag atttatttac ttttttgtat agatttcgat tgttccacct agtcaataca
    77581 aatgaggtaa tcaggaaact gaaaaaaatc aatacaaaaa agccgattaa gaaatacagc
    77641 attttctttt ctgataaaaa agcgtacaag gaaaaatcct tggctctttc tggtctcgtt
    77701 aatgggaaaa agacccatat aaaaggaaga acaacgatca tccatcctaa aagagccact
    77761 aacgtttgcc aaatctttaa ccagtaatta ccttttgaaa aatacttatc tttcaccaaa
    77821 attgatgcaa cttcttctct tgttactttt ttcatatcct cacctcacgt ttttttgtta
    77881 cgacgtagga gtttaccata catttcattt cttttcacat aaagtgttcc taaatttttc
    77941 ctaagaaaaa gaacaaaaca tttctcatca gcaaatgaaa aatattttgt tctttttatc
    78001 agttgttctt tttatttttt atctcttaat tatgttgctc tttccaatac gacaatgctt
    78061 ttcattcctc tagatatcgc cgtgtacatt tgtctgcgtc ttctttgctc atctccatcg
    78121 ttttcaaatg gatataagat tacatgatca aattccagtc cttttgctag actcaaagga
    78181 atgatttggc agttttctaa tccatatgaa ttttttttaa tcgattcttg tagcgtttgg
    78241 gtttcctctt ctgtttgggt gataactgcc gctttttctc cttttagaga aaccaaaatc
    78301 tcagctagta ttttcaacaa ttcttcagag gatcgaaaag agcggtattc gggttctttt
    78361 ccttgcggtc ggatcgatac gatgtcgatc ttctcttgat ccacagcata ggttttgaaa
    78421 agctctgtga ttgctccgct agaacggtaa ctatttctaa gatcataccg atggatcggc
    78481 agatggtagt cgtcgaaaca acgcataata tcagcaaaag tagtggaaga attaaagatt
    78541 gcctgattct cgtcacctac taaagtaaag tgagtttttg gaaataattc gatcaataga
    78601 cctaattgtg ccagggtata atcttgtact tcatcaatca atagatagcg aaatgctggt
    78661 acatttacct tttcaacaag taaatgacga atagctaata taatgactgc ttcatcaaca
    78721 gtacgtgtgg gttgccaagc ataagctgag ccatatcgtt tttcataaat tctttcaaac
    78781 aactgatgct catccaccca tgccatttct tcgatttgtc tggttatttt tcgatatttt
    78841 ttttgtaaaa gtttccttgc ataagctaca atactttgtt ccgaatcatc agaaatcaat
    78901 ttaccgaata attccaactg cctatcttct gtcaacgaga gtacctgatt ctgcacagca
    78961 ggactttttg cttgtttcaa aagatgattc ttccattcgc tcatcagtgc ctttttcgtt
    79021 gcttgaagcc tatcgatcaa tttaggatga gcaggaactt tctcatatat tttttcgatc
    79081 gtttttttag aaaggactgt ttttccattt ttagtaagtc cacggataaa attcggatga
    79141 tctaaaaaca aaggatctga ttgttttaga ttatcgataa actttttgct acgcaaacgt
    79201 tctgtctgct ccgatacatt ttctcccgtg atacgtttga aataagcctc ttcaccttct
    79261 atttcctctg ctgaaagctg tgaaaccagc tgtatgatgg ttagattcag tggatttctt
    79321 tcacctaatg atggtaggac attcgaaata tagtcgataa accgatgatt aggtgataga
    79381 atcagcaagt catcggatgt catcgtatct cgatataaat agagcagata cgcaatacgc
    79441 tgcatgatag cagaggtttt accacttcct gctacgccat ttaccaagat attttgactt
    79501 ttcacatccc gaatgattgt gttttgttcc gattggatcg tagcagtgat agccttcatt
    79561 tcattggtct catcttggcc taagacttct aataatacgt catcttgaat agctacagac
    79621 gtatcaaaaa acttgaccaa acgatctctt tccaaaagaa attgtcgtct ttctttaata
    79681 accgtatcga ttttattttg acgaaccgta taagaagatg gaccaatcat gttattgtaa
    79741 aaaagttcgg caattggtga acgccaatca taaacaagat tttcatctgc atcatctgtg
    79801 aaatttgctg taccgatata aaaggattct tttggctcat tatccagaaa gtctacaacg
    79861 acttttccaa agtagggact tttcaataaa cgttcgatct ttgctagctg attttctgcg
    79921 tttttctgtt tgatattcat ctgatcgatt tctctatttt tcatttcaat catcgaaaaa
    79981 gtatccaggt tatctaagta actgtcaaaa ttcaatcgaa gctcgccagc catttctttc
    80041 aacgactggt ttccttctat ttttgccgta tccatcgatt cccgcagttc gtttttttta
    80101 tcaattagct tttgatacac gttcttcaga tatgcttctt ctaactgttt ttgtgtgttg
    80161 accatacaca ttctcctctt tttttaaagt ggtggaaccg attagtttac ctcttttaag
    80221 agtcgaatgc aagcttttta acgagtatca tttgttagga tatatcagtt cttcaggtcg
    80281 gacagtttga tataaagaaa atgcaccatc aaggtttttt acgtggtagc cagactgctt
    80341 caagattctt tccgctagat agctacgtaa tccgctatga cagctgacga tatattcttg
    80401 ttggctgtct aattcattta atcggtcccg aagttcattc aaagggatat gtttggcttc
    80461 cttgaatttg cccttttcca attcttctgc tgttcgcaca tctaataaaa tttttccttt
    80521 tgctagttct gtcggcaatt catgccattg tacggtttca ctaagccctt ctgcaatgtt
    80581 cattgctgca tatcctagca tgtttactgg atctttggct gagccaaatg gcggtgcata
    80641 cgtcaattct aattccggta aatcgaagat cgtcaaatgc cctttgattg ctgttgctaa
    80701 aatatcgatc cgtttatcca caccttttgc cccaacacct tgtgcaccat aaatctcgcc
    80761 agtctctgga tggaagatca acttcagtaa aatatctgtt gcttctggat aatagcttgc
    80821 atgatctttt cctgatacat gaatgacttc aaaagacagt tcgttttctt tggctgttct
    80881 ttcacttaaa ccggtggatg cggcagtcat tccaaacgtt cgtataattg ctgttccaat
    80941 accgccttga tttcttcgag aaattccgga aatcgtgtcc gcaacttgtc taccttgacg
    81001 attggctggt gaagcaagag aaataagtgc atcttttcca gtgatttgct gttttacaac
    81061 gatagcatcc cccaccgcat aaatatcagg aatattcgtt tgataacgtt cgtctactag
    81121 gatacccccg cgtatgccta attcgattcc agcggtcact gctagctggt tatcaggacg
    81181 aacaccaatg gataaaataa ctaaatcagc agggatggta cgcccatcat ccagtcgcaa
    81241 tcgtttcccg tggtcttcaa atccagcgac agcatgagaa gtaatcactt ctactccttg
    81301 atgagacaat tctttttcta taaaagctgc catttcttca tccagtgttg gaagaatatg
    81361 tggtgcttgt tcgatcacca tgacttctaa acctcttctt tttaggtttt ctgccatttc
    81421 caatccgatg aatcctgcac caacgatcac ggcacgcttt ggctgttttt ctaatgcatg
    81481 catcacttta tcgatatctg gtacatttct aatagaaaaa acattgtcgg cttctgttat
    81541 ccctggaatc gatggaacaa ctggttttgc accaggagat aaaaccaatg catcgtactg
    81601 ttcaatgtgt ttttgaccct catgtacgac ttctaccgtt ttgttttcgg gaaagatggc
    81661 tgtcacttca tgatttggac gcacatctaa acaaaaacga gcggataatg attctggcgt
    81721 ttggacaaga agattttccc gttcactgat ttctcccgaa agataataag gcaagccgca
    81781 atttgcaaaa gaaacatacg gtcctttttc aaaaacaacg atttctgcat cttccattaa
    81841 tcggcgaagc cgtgtagcag cagacattcc acctgctaca cctccgacaa taacgatttt
    81901 catcttattt ccctcctact gttcgatcaa accattgatt catgccacca cgtacattca
    81961 ctacatcata accagatttc tttaattctt tagctgcttg tttactcctc atccctgatt
    82021 gacaaatcac atagacggtc ttttctttgt ctccatcata tctgtttata ctttgtaatg
    82081 gaacattttt agctcctttt atatgcccgc cccggtattc tgcaggtgtt ctaacatcaa
    82141 gtaacgctgg attttccaaa agcttttcct ttaattctgg gactgttatc gattttattg
    82201 attgaaatag caaattcatt ttctgcacct catttacatt tttataaata cctcatgggg
    82261 tatattaaac aggagcttta ttaatatgtc aaccagaatg actcttcatt tttttcacta
    82321 ctttttatat ttgcataaaa taccgataag gggtattatc taattataaa aatagaggag
    82381 aatgtgttat ggagattgat aataaaaata tcctgaaccg tttgaaacgt acagagggac
    82441 aaattcgtgg tatccaaaaa atgatcgaag acgaaaaaga atgtatggat gtcatcactc
    82501 aattaagcgc tgttcgttct agtattgatc gcgtaatggg catgatcgtt gcagataatc
    82561 tgaaaaattg ctttgagaaa cctgatagta atccagaaga acaagcggct aaactagaac
    82621 aagcgatcaa gatgattatt aaaaagtaaa ggaatgattt caatgaaagt cgttttccat
    82681 attgatgaat tagaaaaatg gtcagaaaca gggaaaaacg taaaaaacct gataaaagct
    82741 tctccagaaa cgacgattgt cgtatctgta aatggcatcg cgattaccgg ttatctagac
    82801 tctgccaatg cagaattctt agatttgcaa ggagtcgttt ttcacgcttg cgccaatgct
    82861 atgcgtgcta atcatatttc agaaagttct ttacctgaac aagtaatcgt tgtaccagca
    82921 ggtgtccttg atttagttga actgcaatcc caaggttatg cttatatcaa gccttagtca
    82981 gtagaggttg cgacagaagt gatcagcttc aagaaatttc ggcttatttt tcgaagaagc
    83041 tacttctgga aaaccgtgaa tcaaaggttg tgaaaacgct gtcctgcatc aagtaataag
    83101 aacagccaaa caaaaatagc ttctcatatt tttcgtttgg ttgggcttat taccgcagat
    83161 gcaagctttt gaacaccgtt taaggaagag gttgtgaaat cagcggtttg acctaagtat
    83221 tagagaaaaa aacgggaaaa tagctcctca tattttgccg ttttttgagc taataccgaa
    83281 ggtcagctga ttgaacaccg tttaaggaag agattgtgaa aaagtcgctt agtttcgagt
    83341 attaagaaaa attttgtaaa aatggatttc tacatttttg cataaatttg gcttaatacc
    83401 gagaaactgg cttttgaata ccgtttaagg aagaggttgt aaaatcagcg gtttgacctg
    83461 agtattagag aaacaaacgg aaaaatagct gctcatattt tgccgttttt tgagctaata
    83521 ccgaaggtca gctgattgaa caccgtttac caagaggttg tgagcctacc atttaactcc
    83581 gaatcacaag aaataatttc aaaaacaact tctcctgttt ttggttcggt tggcttatta
    83641 tcgagaagta gctactggga gtctatttat caaaaaaagg aatgcgacat aggtcacacc
    83701 ccttttttat tttctttgaa acatctttcg gtactcgaca gcatacaaga caaaagattg
    83761 taaaagaccg taagtgatga cggcaaaaat gactctcacc cacagcgttg gtaattctgg
    83821 gaaaagcagc aaaaggatca tgccaacata gatgacagca gtcgctactt tgccatacca
    83881 cttcgctcca cttaatttga tatttttaga tagcccgatt aatccagcta caaacataaa
    83941 gccttctttt atcaagaata gaccaaacaa cagccaaagc cacggtcgat accatgccat
    84001 agacaaaatc agaaaaagtt gtgtcaattt atctgcaaac ggatcaagca ccttccctaa
    84061 gtctgttacc tgattatatc tccgagcaat gaccccgtct agataatcag acaaacctga
    84121 gacaacaatg accgctcctg ctatataaaa tgactgtctc agcacaaaat aaagataaat
    84181 cggcagcaaa aaaatacgga atatcgataa aagattcgga atcgtttgta tttctttacg
    84241 ccagtctgtg cttaatttca ttttatcgcc ctacctcctc agcactcttt tctttttatt
    84301 ttagcttaca cggggaataa aaccaatgat ttcactgttt ttatttttct ttacagacac
    84361 tgatattatg agctaatttg agataatcac ttgctgtttt catcgtttac tcttctttct
    84421 tcctgtcgtt tgcgcatttc ttttactagt actttatgag ctttttttga tcctcgctct
    84481 aggtcacgct gccgtttacg tgttttataa tcgataaaca gactgtctaa atcgtaacct
    84541 gtcgggtaca gatcttctgc tgaacgcacc agacgaacac gctgacgagg cacgtggatt
    84601 atttttttgt ctaaatatac atcaatcgta tcttcaccta tatcttcata aactaacgct
    84661 tctttttggt attcattgac aaatatccga tcaccttttg caaagagctg acgttctttt
    84721 ttattctcct tcctatttgt aactgctgtc ttaggaagaa attctttttt ctgtgtccga
    84781 taggcttttt ccgccaagta acgctctgct tgatggatca atttcatcga catatccatt
    84841 ttatgagcaa tccacaaagc ttggctttct cctgtttctt ccaacccgca actgatattt
    84901 aggacgaagt gcttcccgat cgaaagccat agcagccggc acaaaatctt catgatctcc
    84961 ggcgaatttc ttgatttctc cataatgggt cgtggcaatg atcaatgccc cttgctcata
    85021 catagattcc atgattgcga tcgctagtgc agccccttca tttggctctg ttccactgcc
    85081 aatctcatct aaaagtacca acgtattcct ttttatcttt ttcaaaatag cagcgatgtt
    85141 ttgcatatga ccagaaaatg tactcaacgc attttctaaa ttttggtggt caccgacatc
    85201 gacgaaaatc tcatcaaaga cagcaagctc tgtcccttct tttgccggaa cttgcatacc
    85261 gaacatcgcc atcaaagtca ataaaccgac tgtcttcaac acgactgttt tgcctccggc
    85321 atttgctccg gtgataatca agcctcgata gtctttaccg atttcaacat ccaatggtac
    85381 cgcatgctca ggtaaaaatg gatgtctgcc ttgcttgata atgatatgtt ccgatttatt
    85441 gattctaggt gtgcttccat tgatttctcg gctaaatttt gcccgagcaa agatgatatc
    85501 taacaccgtg atcgtttcga tcaataaatc gatcacttct tcgttttctg cgatagcacc
    85561 agtcaatgcc gccaggactt gatattcttc actgatttct tcagctttta acaactgata
    85621 gtgttcattc aatttagaaa tcacagttgg ttcaataaaa accgtcgttc ttttatttga
    85681 ttcatcgata atcgttccat ctattttatt tttatagctg gctttgatag gaatcgtata
    85741 gtattcgcct ttttgaacaa tcattgcttc ttggatcatt tctttgtttt tcggatgacg
    85801 caagaatttc agtaattttg actggatttc tttttcgatt agttgtaatt gtttgcgtac
    85861 tttacgcaaa ttacgtgacg cgtcgtcact gactttatta ttttttattt tctggtcaat
    85921 caactcttct acatttatca aatcaggaag atgtttgcta taagcaaaca acaagggtgt
    85981 ctggtattga ttcttatcaa aaaactttgt gatcatccga ctgcttctaa gaaaatccgc
    86041 atattcgatc aaatcggttg gctgcagaat caaccctttt ttgacttgtt ctgtcagtgc
    86101 atcgatcctc ggcaacccca taaatggaac atgctgactg ctttctaaga tcaagcgtgc
    86161 ttctcttgtt tcttcttgac gatccaagac agtttgtagg tttgtcgaga ccgtcatatc
    86221 gctgattcgt tttttgctat agtttccaat tgctcttgct tggatttcct ttttgatccg
    86281 atcaaattgt aattgactaa tcatttcgtt gtccatattc tctccttttc ttgaagagat
    86341 acctgtccca aaataaataa gggcctagag ataaataaaa ggatagaaca cagcttaaaa
    86401 aagtcatgtc ctatccttat tagaatacaa agatattgtt ttcctgacag gtaccgtttc
    86461 ataagcacac caaataaact ttgtttattg gctattcgac ttactgatta gataccagct
    86521 acactcacaa aacatacccc attcttctag gtcttattta ttttccactt aactatagca
    86581 agacacattt tggttgtcaa actttagtat gttttataga tttacaccat taatgaatag
    86641 acacctaccg cgataattgc tccgatcatt ggacctgcga ttggtaccca tgaatatgcc
    86701 caatctgaag ttcctttatt agctattggc aataccgcat gtgctaatcg aggaccaaag
    86761 tcccgagcag ggttgattgc atatcctgtt ggccctccta atgaaagacc gatggctaag
    86821 atcaatccac ctacagcgaa tacgttcgtt ccaggtgcaa attcgttttg tccaaaagct
    86881 agcaacccaa gaactaatac aaatgtacca attaattctg tgatcacatt tgctggataa
    86941 ttccgtatag caggacctgt tgcaaacgtt cctaaaatcg cgctttcatc tttcgttgca
    87001 ttccaatgtg gcaaataaga aagccaaaca agaatggccc ctgcaaaagc tcctaaaact
    87061 tgcgcaatga tgaaaggaac gacaagattc caactaattg cccctgtcat cgccatagct
    87121 agagagactg caggattcaa atgagctggg cccatgaatc cagaaatata gacagccatt
    87181 gttacagcga gtccccaacc aaatgcgatg acaatccagc cagaagcctg tgctttactt
    87241 ttgtttaaat tcacagccgc acacacacca tctccaagca aaactaggat cagtgtccca
    87301 ataaactccc ccatgatttg agtcatatca ctgttcattt atttctcccc ctttagttcc
    87361 cgcagatctg attctgcaat caatgcttct aaacgtttag tctgttgcgc cttctcctct
    87421 tctgtccatt caaaatatcc agcaattgca tcgatcacag gttgcttgat ctcatcaagc
    87481 tgatctcgtt caaacaacag atgatttgta cgacgaatga gataatcgcc tggggccaaa
    87541 accatttctt cttctaaacc ataacgtaac cgagctgact cagcgagact caaaccagga
    87601 taaggtgcca tttcttttgc taattcaaag atacgtcggg cattagtccc gtaaaaatca
    87661 gcgatataag tagcatcttc ttcctctaaa ccggctgcta ctccttcttt tgctaattct
    87721 gtcactgttt cttctaattt agttggatcg aagtttccac ctgaaatctg atatttttta
    87781 gagtcgattt ctttcgtctc tattccgtat tcttctttta ataattggcg tatcaatcgc
    87841 aaagctcctt ctgccatctt acggtaatcg gtgattttcc caccagataa agtcagcaaa
    87901 ccatctggtt ctctttctaa agaactacct ctggaaatcg tagaaggtgc tttttcatca
    87961 cggctgtttt ccaaatggtt caacacgtct tctacttcag cacgagaaac tttgttttcc
    88021 ttatattcac ttactgtatc gacaacttta ttgaagctct tgtctgaaat cgatccatta
    88081 tctccaccat tgtaatcaga accagaatta ccaatcaaca gtggacgaag tcctgcccag
    88141 cttgcttcga tatcattcaa tgtgatattt gcttctggat agcgatgatt gatcacatcc
    88201 aatagataat ctacatcttc ttgtgtgact ttcggatccg taaaatctcc ttggtaatcc
    88261 gtatctgtcg taccaaagta agtcttgttt tctcttggaa tagcaaaaac catccgccca
    88321 tcttgctttc ctgtatcgaa gtatgtgggt tgcggtacag gcagtttttt cgcatctaca
    88381 actaaatgga tccctttagt tggacgcatt ttaggagaga ctggacgcgt aaaattcaag
    88441 tttcgtactt tatctaccca aggaccactc gtattgatca ctaattttgc tttgatttcg
    88501 atcacttcat ctgtcagcag gtcacgagct ttgacgccaa cgatttgatc gccatcatat
    88561 aaaaagccaa ccgctttcat tttacttact agataagccc catcttcggc agcctttttg
    88621 atattatcaa tcactaaacg ggcatcattg ttgcggaaat ctagatagac acccgcgcct
    88681 tttagccctt cttttttcaa aaacggttct ctttccaata cttcttctgg tgtcagcgta
    88741 taattctcat atttggttcc tgtcacattt gccagtttgt cataaaggtc cattgctact
    88801 ttgaccgaga acatattgaa ggttgttgct ccttcgccct catagattgg caaaagcatt
    88861 ggatctggtt ttgggatgtg tggggcaata ctttgtacga ctgcacgttc accaactgtg
    88921 tcagctacta cttccacatc aaatgtcttc agataacgaa taccgccatg aacaagtttg
    88981 gtcgagcgag aggaagtccc ttctgcaaaa tcctgcattt cgatcaatcc tgttttgatt
    89041 cctgatgctg ctgactggac tgccacaccg gcaccagtga ttccgccacc gatgatcaac
    89101 agatccaatt cttcttgctg cattttttga atgctatctt gtcttgtctt gtttgaaaac
    89161 atatggattt cctccttatt caaatgcttg ggtagctttt actgcttttt tccaaccgtt
    89221 gtaaagtttt tctcggcgct cttcctccat ttgaacttca aatagcttgc cagcttcata
    89281 aaattcgcgg atctcgtctg tatctttcca ataaccgaca gctaatcctg ctaaaaatgc
    89341 tgcccctagc gccgttgttt ccaagttttc tgctcgttgg atcggtacat tcaagatatc
    89401 tgtttggaat tgcatcagat attcattgtt tgctgcaccg ccatctactt tcaatacagg
    89461 aatcttgatt ccagtgtcat cttgcatcgt atcgatgata tctctcactt gataagcaat
    89521 cgactgtaaa gtagctttaa tgatatcttc ttttgtcgta ccacgtgtca agccaaacat
    89581 agcccctcgt gctgcctgat cccaataagg agcacctagc ccaacgaatg caggaacaac
    89641 ataaacctca tcttcgcttg tagagcgttt cgctgcgtct tctgaatcgc tagctttttg
    89701 caacatttga agtccatctc tcagccattg aatcgaagaa ccagccacaa aaatacttcc
    89761 ttctaaagca tagtaaacct ttccatttat gccgtaacca attgtcgtca ataaattatt
    89821 tttggataat tgcggttttt caccggtatt catgacaata aatgaacctg taccataagt
    89881 attcttgacc atgcctggtt cgaatgccat ttgtccgaat aatgcggctt gctggtctcc
    89941 tgccatccct gaaattggtg cttcgcttcc ataaaaatga taaccttgcg tataaccata
    90001 aacttctgag ttagaagtga cttttggtaa catcactcga ggaatattta gtaaatctaa
    90061 aatctcctga tcccaatcta gctgatggat attgaacaac atcgtccgac tggcattcga
    90121 gtaatcagta acatgtgctt gtccatcggt cagtttccat actaaccaag aatcgatcgt
    90181 tccaaacatc aattcgcctt tttcagctcg ttcttgcgcg ccttctacat gatcaagaat
    90241 ccagcgtatc ttcgttgctg agaaataggc atcgatcact aaccctgttt tttcgtggaa
    90301 aaattcttga tagccttcat tttttaagtt atctgcaatt ccagctgact gtctggattg
    90361 ccaaacaact gcatgataga ttggacgtcc tgtatctttt tcccatatta ctgttgtttc
    90421 acgctggttc gttatgccaa tcccagcaat ctgatttggt ttgatccctg attcgatgaa
    90481 cgctccggca ataactgact gtacagaatt ccagatttca tttgcatcat gttccaccca
    90541 actttcttgc gggaaatatt gcgtgaactc tttttgagaa ctgccgatgt gtcttccttt
    90601 cttgtcaaag ataattgctc gtgagctagt tgtaccttgg tcaatcgcca tgatatacgt
    90661 tgattctgtc attgtgattc cctccattat atgcaaacgc tttctttaac tactcttatc
    90721 atactactgt tttaaaaaaa gaaactgtca aaattttatt ctttttttct ttttttgaca
    90781 gttttttatt atgaagctat tttttaatca attcttttct tttttcagcg tctctattct
    90841 tcttttcaat cgaataatgt cgtaaggtga cgcaaattct gacagataat attcacactg
    90901 ttttttgttt ctctggcaaa atgtgatcac caaatcatat tctttacctt cttcataact
    90961 tccaatctca ataccgccga ttcccctcag ttctctgatc agatattgtt gaaaagcaat
    91021 acgataaatc ggcagacttt ctaaatcgat tccaatcact actggttttg caatataaaa
    91081 atcgatcatc aaaagaacat tggcatactg gatcatcagg taactaagct cactatcttc
    91141 agctcttttc ctcggcaatt gctgcaccgc tgtttcctgt aatttcgcca gtaactgtgt
    91201 taaggaatgc ccgagcattt tctgctgctg ttccaaaagc cgatcacgct catagacttc
    91261 gatctttcca acaaagaaaa accattcatt gttgatctgg gaaatttggt agcctactgc
    91321 cttttcttct ttgattttca aacgacgagg acgataatgc cataacatcg tttcccgaat
    91381 gtaagtatct aaaacagcgg ttggtaactt tttgctccgt gtcaaatcat actgataaaa
    91441 tatttcttcg tctactatcg aaaaagaaac aaaaaagctg taaaacatca ttgtttcgta
    91501 tacattcagt tctgctgctg ttcgactaag atgcatcacg atgattggat cgattgcttg
    91561 ataaagccgg tccgactgat agagtaattt cttttctttc aaagttgcgt acgtactttt
    91621 ttcattcaat agtctttttt tcgtaatccc gagccagcaa gcaatctgtg cttctgctga
    91681 tgccgtaaac gttgtttcta atacacggtc caatcctaga atgaacggtc ttttttctgg
    91741 tgtattttgc aaaaaaagcg gtcgctgatc ttccgggata tattggaata gttcataata
    91801 aaaatatcgt atctgtagct cttctccgta taattgaccg tttttgattt gtaatccaaa
    91861 ttcctctaag agctggttca attctttgat ctttcgaaaa acagaagact cactgatatt
    91921 aaacgctgtc gctaatcgaa cgatggatac ttgctgatgt tctaataaat agacgagcat
    91981 cttaaacttc aagctttcct gcaataaaaa caatagaatt ttttccaaac ttacatcttc
    92041 gtccaacaca agcagcgcct gatactcatt tcgctgtact tctacttttt tttccatcat
    92101 tcggccaatc aattcaatat cttccaaata ttgatcaaac gaggcttttg acagttggac
    92161 atgctctctc aaaccattga tagaggctgt tcccccttgc agaacaaggt ttcgcaaaat
    92221 caggatctgt aactgctctt ttctttctaa taatgcttca atcttcatag gcagtattcg
    92281 ccacctttga ccacaccata tctggcacac ggtattctgg ctggaaaaat agctcatgtt
    92341 cttctaactg ttcaaacgtc catccttctt ctactgcaat tgtcagttgg tcaagaaggt
    92401 ggaacatctc ttttttgctt tggagctgtg ctccaagaat ctttttttca gaatcaaata
    92461 gaaatttgag tttaactttg ctttgattta ttgctgtaag cttgtagtct acgtatcctg
    92521 tttcaatttt ttggggataa aaaatgctct cttcttctgt caaacctacg cttcctaaga
    92581 aatagccaaa ccactgattg ccgactggac gataggttcc ctgatccttt gtctgtgagc
    92641 cactaattgt cttgctgaca tttcgtgctg tacggacagc gttatttact agagaaacat
    92701 acattttttc atttgttgga cgaaaagtta cttggatcgc atcgccaatc gcataaacgt
    92761 ctttttgaga cgtttgcaag tagtcatcta cccagatcgt tccatcatca ttcaatgtta
    92821 attgttcttc ccacatctga ttgtcgggac gagaatgatt agccagcaaa acaagatcat
    92881 agttctcctt tcttttttcc gtctctacaa tagcggtttc attttcggtc aaagacacaa
    92941 cttgttcttc taaaaaaagt gaaagccctt gatttttcat ttcctttact aacggttctg
    93001 tcatttcagg atctagataa cgaaaaagaa ttgactttcg gctttcgtaa agatggattt
    93061 gtttttttct tgatgccaac ccttcagcta tttcgattcc tgcttgtcct gcaccaataa
    93121 ttgcaatttt ctttgcattc atgatctttt gctgaagagc cgttacgttt tgtatctttt
    93181 taactgggtg aataagcgtt gattctgcag aaatatttcg aaacttttga tttgaaccag
    93241 tcgctagaat caaacgatca aaatccaatt tttttcctcc tgctaaaacg actttttttt
    93301 ctttcaatcc tattactgtc ttttctgtgt aaacatggat tcgatagcgg tcagtcagtt
    93361 cttctttcgt gatccaagaa agttgttttt cactggtaac ctttcctttt aatatcaaat
    93421 tgaacccgct gggaatccat cctaacttcg attgcttttc aatcaaatat atttcacttg
    93481 ttggcatcaa ttggcgaaga taaatagccg catgaatccc tgcaaacgac ccgccgacaa
    93541 ttacaatgtt catctgcatt cctctttctt ataaggtgtt ctactgctaa cttctcaatc
    93601 agaaaacaca gtattcataa ctcgctttca accttatgat acatagcgat gcagcagaat
    93661 caaccctctc catcataccg tgttctaggt ctgcttctca ataatgtact agtggaccta
    93721 attgaagagt atcatttctg aagagatgtt tcaaaaaatg tactcttata aaagaaaaaa
    93781 actcgccttt tacgtacctc tgtccaaata ggaaacagaa aagaacgaaa agacgagttt
    93841 tagcgtgtgt aatgtaatag ttagaataga cacatcattt atttttaatt ctttaatgct
    93901 tcaacaactg cttcgcctaa ttgatgagca gattgaggat tttgccctgt aagaagccgc
    93961 ccatcaattt gaaccacttc tgaaaaagct gctccagact gatagtttgc tcctttttct
    94021 ttcaaagcat cttctgctaa gaatggtact tcattcgttg taccatttgc ttcctcttct
    94081 tcattactga acccagtcac tgtacgtcca gctaaaatag attttccaga ctcatctgta
    94141 actggcaaca atcctacaac accgtgacaa acagctgaga ccagcccttc atttcgatag
    94201 atttgtgaag cgactttccc aagatctatt gcttctggaa aatcccacat tgttccgtgg
    94261 ccaccagcat aataaaccgc tgcataatca tttgcatcca catcatcagg acgtaaggta
    94321 tttcccaagg cccgatttct gaaatcttca tcttcataat aggcccaatc gatttcatcc
    94381 atattcaaaa cactttgcgg ttctaaaggt acatatccgc ctttaggact gacaaaatct
    94441 gcatcgatcc cattttttac taatacatca taaaaatgag tcagttcact taaccacaaa
    94501 cctgtaggac gctcgatctt ttcgtacttt tctacatttg ttaatacgat caatactttc
    94561 attttcccat cctctttcta taaaaattgc gttattgata acgtgctttc aagaaattat
    94621 ataatgggct tggcaaataa agctctttat atgcttcttc aaaaggtttc gttacaaatt
    94681 catcctcacg gttttccaat aatttctctg cccagtcagg atcgacgatc atttgctgtc
    94741 caattgctgc aagttctgca tatttcaata cctgctctac atcttcgcga ttgcggatcc
    94801 caccgacacc aactaaaggg atctttcctt gaatcgtgtt atggaccact tcaagaatcg
    94861 atttatcgtt gtatttatca gaacgagcta ttcgatcata catatttaat gaaacatgca
    94921 gataatctag ttttgactca cgtaatcgtt caagaagcca gatcgtgtct tcaaaacgga
    94981 tacctggtgt ttcatattct tctggtgaga aacgataccc tacgatgaat ggttttttag
    95041 catattgttc aaccgctgag aaaaccgttg ttaataattc ttcaataaaa cgataacgat
    95101 tttccaagct accgccccat tgatcctctc gtctattcga atgcggagag aaaaattgtt
    95161 ggatcaaata cgtatttgct ccatgcaact cgattccatc aaatcctgat tcaatcgctc
    95221 tacgtgtggc tttgccaaat gcttggattg tttcaacgat ttcttcttca ctcattgctc
    95281 gtggtgtttc cgcatcagga cgttttgctg caactgcact tgcagataca ggctgttctc
    95341 cagataaagt tgctcgactt gtcattcgtc caccgtggaa aatctgaata atcgcttttg
    95401 cgccttctcc ttggattgct ttcgctagct cacttaatcg aggaatcatt tcatcatgag
    95461 cgatgctgag ttcacctggc cagccttttc cgatatcttg gacatttgca gcaccagtaa
    95521 taacagcacc aagaccttta gaacgttgtt tataataagt gatctcatct tcggtgatca
    95581 ctccattgaa aaagctgagt tgtgtcgtca taggcgacag catcaatcgg ttcttcaatt
    95641 gaactcctga aggtaaagta attgattgat caaattgtga cattgtcatt cctcccataa
    95701 ttcgctctga ttaacctatc gagaatcatc tatcattaaa ccactcgatt agttgtacat
    95761 gcaactaatt tgcttaaaaa attttatttt ttttgtaact tatctgttgc atcattcatt
    95821 gtctgggcta attctttact tgcttcattt cccaaaactg ctttgtatga ctgatgaagt
    95881 tcttcccagc taccatcgac ttccttagca aattggcgtc cttgttctgt aagataaact
    95941 aatgacaagc gaccttcgct aactgttttg acgtatcctt tatattctaa tttttcaaca
    96001 aaacgagcaa tcgttgatgg ggcggaatag agcatttgtg caatatcttt ttgtggtatt
    96061 ccatcttttt cttttaatat caataaaata aaaccataag ttggtgccag acctgtcctt
    96121 ctaaacgctt catcagctaa tttattcaac atgcgatcta gctttttcac gctaaagaaa
    96181 agacattcat ctaacgcttt ttcaattggc ttttccattt catcccctcc attggcgtac
    96241 atatcatagt atgattttta ttttttgtca aaaaacacgg aataatgtcc gcctcctctg
    96301 tctagatttg aaaaaaagaa gtagccatct tcaaagaatt tcggcttgtt ttcgacaaaa
    96361 ctccttctgg aacaccgtga atcagaggtt gtgaaaaagt cgtttagttt tgagtatgaa
    96421 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgaaaa
    96481 actggctttt gaacaccgtt tatatcagag gttgtgaaaa agccgtcctg catcaagtaa
    96541 taagaacagc caaacaaaaa tagttcctca tattttgtcg ttttttgagc taatgccgat
    96601 ggtcagctga ttgtacaccg tttattgaga ggtcgtgagc ctgccgttga actccgagtc
    96661 acaaggagca atttcaaaaa acagcttctc atgttttatg actatggtga cttgtgatcg
    96721 aggagttggc aggagaatac tgtttattcg taaagaaggg gctgtgacaa gacttttgtc
    96781 acagtccctt atttcctttt attataggat ttcgccattt gattggatga cttgtctgta
    96841 ccaatcaaat gattttttct ttaaccgttt ctttgtgcca ttcccttcgt catcttgatc
    96901 aacatagata tatccataac gttttgacat ttgtgaagta gaagcgctga cgatatcaat
    96961 gcagccccac gacgtataac caaataaatc tactccatct ttgatagctt ccttcatctg
    97021 ctcaatatgc tgcttcaaat agtcaatgcg gtaatcgtct tgaacggttc catcttcttc
    97081 tactttgtct atagctccga gtccgttttc agctatgaac agtggttttt gatacctatc
    97141 atataattga ttcaaagcaa ttctcaaacc cttaggatca atctgccagc cccattcact
    97201 tgatggaaga tacggatttt taattcctcc agttattaag tttccttgga ccccttccca
    97261 attttctgga tgagcactga ctgcactaga catgtagtag ctaaaagaaa caaaatcaac
    97321 agggtaggct gctaagattt cttcatcacc tacttctatt tttaagttga cacctttttc
    97381 ttcaaacatt cgttgcgtat acgctggata atatcctctt gcttgaacat cactaaagaa
    97441 caaagaagtt ctttgctgct caattgtttt ttgaatatca tccggatcac aagaatacgg
    97501 aacaagaagc tgatagctga tcatacaacc gacttgtgaa cctttgataa tttcatgaca
    97561 agcttttgta gctaaagcac ttgctataaa ctgatggtgt gcaccttggt atttcgcttg
    97621 ttccaaatgg ggatggtttt cttcaattac tcctacgcta acaaaagggt gatgttttac
    97681 acagttgatc tcattgaaag tcatccaata ttttacttta tttttatagc gtttgaatac
    97741 tgtttcagcg aaacgaacgt aaaactgaat aagctttcga ttaggccatc caccatattc
    97801 tgtaaccaaa tataacggca tttcataatg ggaaagagaa acgactggct caatcccata
    97861 ttttagacat tcgtcaaaca cttgatcata aaaaaataat cccgcttcat tgggtgtttc
    97921 ttcatcacca tgaggaaaaa ttcttgtcca tgcgatagac atccgatagc atttaaaacc
    97981 catttcagca aataaacgga tgtcttcttt aaagtgatga tagaaatcat ttccgtgtct
    98041 tttaggataa taatacttgc tgttgggatc ctgcgccgct tttacttgct gatgcgtcat
    98101 catatgccat tgatctgtcc atttttcttt aggtaaatcg ctgtcgaatg tatacacatc
    98161 agacacagat aatccttttt catctacatc ccatgcacct tcacattgat tggccgctgt
    98221 cgctccgccc cataaaaatc cttctggaaa ttttttcata tcgatccccc taaacttgct
    98281 agttttcttg tttgattatt tttcttatga ctagtaatga tatttttgaa tctactacta
    98341 tttgtaacaa taaccattgt ggtcggatca tatccctctt tgattaattc ttgcaaatct
    98401 acttccatca ataaatcgcc tttacgtact ttttttccat cagatactgc actttgaaag
    98461 tatttgccat ttaaattcac tgtatcaata ccgatatgga tcagtatctc tgctccttct
    98521 tcactgacta ccccaattgc atgtttcgtt ggaaaaactg ttgaaacttc cccgtttaca
    98581 gaactgtaga tttttccgtc cgttggaatg atcgcaaacc cttctcctaa agatccacta
    98641 gcaaatgttg gatcgtttac ttcagataaa tcaattattt cacctgctgc aggagtactt
    98701 aacactatat cctttgagga ttcttcttcg atttcatcct tgtagccgaa aagaaaagtt
    98761 agcatacagg aactgatcat cgctaagaaa taactagcaa ctagccaaac aaatccttca
    98821 ccaatataaa tcgggaaaga caaaatactt cttgtagcaa ctgccaaagc accggctcct
    98881 gcggcaccag ctactccacc aaatatagct ccacatatac aagcaatgta aaatggtcgt
    98941 ttatatttaa gagtcacacc ataaacagca ggttcagtga ttccaaataa tgctgtgata
    99001 aatgcagata aagataaact ttttactttc ttatttttcg ttttcaaaaa taccccaagt
    99061 actgctcctg cttgcgcagc tacggcagtc atacatgctg gacctagcgt atcacgaccg
    99121 tagaaagaaa gattgttggt cattactggt acaagtcccc aatgtaaccc aaaaatcact
    99181 aacacttgcc aaaatccgcc gataacagca ccagataaaa cagggctaaa gttataaaca
    99241 gctaaatatc cagctgcaat cagctgactt gcataatctg caattggacc tacaactaat
    99301 aaaataattg ggaccatcac gatgatacaa atgaatggtg tcaataaatt tcgaatactt
    99361 tcgtgcaagc ttttgcgaat cttaggctca atataagaaa gaacccatac agctaaaatt
    99421 gctggaataa ccgtacttgt ataccttgct agaatcacgg gcatccctag aaatcgcaag
    99481 gttatgctat cactatatgc actgacaatc gtaggataaa cgagagctgc tgcaataacc
    99541 atagcgatga aacgatctgt attgaacttt tttgcagcag tatatgccaa aaatataggc
    99601 aagaaataga aaaatgcatc agctgctgca ttcaaaatga tataagttcc tgattcagta
    99661 gttaataaat tcaaactcgt acataaggcg agtactcctt tgatcaaacc acttcctgcc
    99721 aagacgccta aagtcggggc aaaaacagcg gcgatcatgt ctataaaaga gtttaaaatg
    99781 ccttttttct cagttcctct ctttccacta gatgcatcat cttctagttt catttgtttg
    99841 gataatacgt catacacttc atttactgca tttcctacta cgacttgaaa cattcctcca
    99901 gcttcgacta cagtgatcac accttctagt tgctctacct tctccttatc tgccttctta
    99961 ttatctttta gggtaaagcg taaccttgtt gcacaatggt aaacattgct gacattttct
   100021 tcgcctccga caaatcggac aatatctttc gctaattgtg aatagtccat ttttacttcc
   100081 cccttgttaa ttaatgccgt agcaatcctt cttacaagat aagtatagtt cttagaaaac
   100141 ggtttctcca ttcaattagt accccttcta atagcgaacg aaactgtaca atagtgtgta
   100201 tggtttactt agccgagcaa atcactcact gcttgaaaga aaacaagtat atcgtttctc
   100261 ttatagtcaa aggagacaaa aaaaacacgc ttgatcttcc tttgctgatg tataagtggt
   100321 atctcaagct gatactctgt gatttttgtt tctacttggc ttttgataag acagcacaac
   100381 aaagtctcgg catttaacgg aagcataact aggtcagaac taggagagat tagttgctga
   100441 atggaatcta tctttttatg gatttttatt tgattttctt ctttgtagta atgatcaagc
   100501 agttttgttt tctttttttc ttcaactatg gtcagctttt cacgcaaaat ctgataaatc
   100561 tcccaagatt caaactcatc tagaacacta ggtagataaa tcaaatcatc ccactcaaaa
   100621 ataagctctt gctcagtagt caaaattgca tcatattccg ttattttgtt tgattgattt
   100681 ttgaaaagat acactggttc tatccggcat tctttgatcc acatgttcat actttgttga
   100741 atctgttttt ttagtgtatt caaaatacta attggctggt tactaacaat cagtatctcc
   100801 ccttgttttc gaaaaggatt caacgcttcg gcaagataca aaacaaaata agcgctttca
   100861 gctaaattgg gacgtaattg aaaatgtatt gggaagaaac gccgaattaa ataaatttct
   100921 aaaggataac gggagatgat cttttgtaca aaatgattca tggtattatg tccggcatcc
   100981 atcctcgttt tcatttgttt gatatgggtt agcaaaaatt ctgtttcatg gaacaataac
   101041 gaaacaggaa gatctaaaaa acgaataatc gtttgctcaa atgctcttag attcttctct
   101101 atttctttgt ttttttcatc attaatcatc aaataattta actctaatag tcgattttca
   101161 attgcttgtt tttcttgatt ggaaaaagaa tagggtagtt ctgatgataa cttttttgtg
   101221 agggtctcta ccatcggaat aaataatgta tacctgtttg ttttttctaa aagttcttct
   101281 cttcgaagaa tggtcaaaac gagataccga gaaaatcgta tgaagtcctc tcctgaaaca
   101341 atataattat atgatataag aacctctttt aatgtctttt ggacagtcgg catgatattg
   101401 gaaaaaattg tactgatttg ttgaggcaac cttgcgtgtt ggatcaccgt ttctgttcca
   101461 acaagagata agaaaattct ttttgaattt tcttcagcaa tgatttttag tccttttgtc
   101521 gacgaaactt ccagttctaa tttaggattg cgctcgatcc aacgcaaaat cgtttttatt
   101581 tgtaatgata cggctgtttt tgaaagaaag aaaatgtctg ctatcttttg catactgaca
   101641 tacccttttt gaaacaataa gtacgtcaca atagttgaag ctcggaaatc catgctggaa
   101701 tagattttat gtttcgtcac ctcttgtatg atttgctgtt tagtttcaga ttcaattgat
   101761 tctaaaaaat aacctgaacg tttatttgac tggataatga ttttcttctc gtagatagca
   101821 agcatatttt tgatttcagt ttggatcgtt ttcttgttgg tacctaaagc ttcagctaat
   101881 tcttcgcttg ttatccaatg attcttattt cttaatacta caagaatttg gagttgtcgt
   101941 ttatttaagt ccatttgctt acacctcctc tttgttataa acatacagga aaaacctctc
   102001 aaatgacaat agtcacttgc agaggtttaa aaatcatttg aagaaagatc tatattcaag
   102061 gtttttacca ttagactgga taatttgttt ataatattca aaactatctt ttttcaatct
   102121 cctaaagctt ccgctcccat cattttgtct atccacataa ataaagccat atcgcttcct
   102181 catttcccct gttcctgccg atacgatatc gattggtccc caccataagt aaccaatgat
   102241 ttggcaacca tcttttattg cctcagcaat ttcctgaaga tgtattttta gatactcaca
   102301 acgttttgga tcgtggattc gattcaattc atctggtgct tcatctagtc caatgccatt
   102361 ttcaactatg aataatggta attcataacg gtctgtcaat tcattcatga cataacgaaa
   102421 ccctagagga tcaattggcc aactccaagg ttcgggagat ttttccttca aaaagggatt
   102481 atcgaaacca tttgctccgc cagtatctac gcgcatttct gcttcttttt tatagacagc
   102541 gctacgataa taactaaatg caatataatc tgccgtgtta gcttgcaagc actgttcgtc
   102601 tccatctaac attactggtg cacagtcttc ttccttccat gtcctgtaaa tataagctgg
   102661 ataatgccct cggcacatga catcggagaa aaaccatgaa ttgcgtttaa attgcagtga
   102721 accaaataca ttctctggat cacagtcata tgcataagtc gctaatgcag aaaagctaca
   102781 cataataccc atcttagcat ttggatcgat tttctttaat aattgagtag cacgggcgtt
   102841 cgctagaaac atatgatgac aggcttgata aatcactttt tttgttagtg tagcaatggg
   102901 ttcaagttta tctctagcag ggaatgtaac caatccagca gctgcataag gcatacgaaa
   102961 agcattattg atctcattaa aggtcatcca atatttcact ttcccttggt agcgttcaaa
   103021 gacggtctgc gcataaaatt caaaaaagtc gattaatttt cgattttgcc accccccata
   103081 ctctcctacc aatgctaagg gggtttcata atgactaaga gtaattactg gctcgatatc
   103141 atatcgattt aatgtattga ttagtctgtc ataaaatacg agaccagcct catttggctt
   103201 ctgttcgtct cctcttggaa atattcgtgc ccatgagatg cttgttcgaa aagcttttaa
   103261 acctaactcc ttcagtaaac gaatatcctc ttcaaatcga tgataaaaat caatcgcttc
   103321 atgagaaaga taatggagtg attcgtctaa agcaatctcc caaatctttt tttcttcatt
   103381 ccactgaata ctaggatgct ggttcatgat cccgataagc gtatctgtca cattaggtaa
   103441 tttgccgtct tccaaccatg caccttcaca ttgattagca gctactgctc cgccccataa
   103501 aaaattttct ggaaatattt cctgatccat aactatctct cctcgctatc aacaatttct
   103561 tacttgaagt atagctcgat tcatcaaaac aagatattct aactatttcg gcagaagaga
   103621 agaaaaaaat tgaatgctac tcttcatttt taatatttat atataacaaa tacataagac
   103681 gatccccgaa agaaaacact cgttaaccat ctaagcaaac gatttatttt acttccaaca
   103741 caaatgcttc ataaggtcgt aaatcaactt tgccgtctgg taactgtttc agaggataat
   103801 ttgacacaat aacccttaaa gcttcacgtg gaatagtgaa cgtctgcttt tcactggaca
   103861 tattacaaat aacgagccat tgctggtctt catatatgcg agaataggca aagacatgct
   103921 caggcgtctt ttccactaat tcatagtctc cccagacgat gatgtcatgt tttctacgca
   103981 aatcgatcaa tttcttgtac atataaaaaa cagaatcttg atctgctaac gcttcttctg
   104041 cattgatttc tttataattt ggattgactc gaagccatgg aattccagta gtaaacccag
   104101 catgttcacg ggcgttccat tgcataggcg tcctagcatt gtctcttcct ttcgccttga
   104161 ttgattccaa gatttcctct tttgtaaatc cagaagaaat cctttcgtta tacatattga
   104221 ttgtctcaat atcttttgct tccgcgatat catcgattgg gcaattcgtc atgcctaact
   104281 cttctccttg atagatataa ggggtgcctt tcatcatatg gagcaagata gcaaacatct
   104341 tggcactttc ttttcgatac acatcgtcat ttccccaacg agaaacaatt cgcggaagat
   104401 cgtgattatt ccaaaataaa ctattccatc cttcatcacc taaagatgtt tgccatttgg
   104461 ataatacttt tttcagttca gagatactca agggtttcaa atcccatttg tctttgcctt
   104521 cttgctgatc taatcctatg tgttcgaatt ggaagaccat ggataattca tttcttttag
   104581 gattggaata aagtttagcg atttcggtag ttgctcccca tgtttcgcca acagtcatca
   104641 gatttttgtc accaaaagtt gcttgattca tttcctgaag atactcatgc agtttaggtc
   104701 cattacttgt gatttcttta tccggttctt tgccaatcat atcgatcacg tccatacgaa
   104761 agcccccaat acctttatcg atccagaaat tcatcatttg ataaatctct tggcgaacct
   104821 gtttattttt ccaattcaaa tcaggttgac gcttgctata caagtgcaga aaatattgcc
   104881 ccgttttttc atccaactgc caagcagaac cactgaatat tgagcgcaat ctattaggct
   104941 cttttccatt gaccggatca cgccaaatat aatagtcccg ataaggattt tctttatttt
   105001 tacgggcctc aatgaaccac ggatgttcat cagaagtatg attcaccacc agatccatga
   105061 tgatacggat atttcttttc tttgcttctt caatcagttc ttccatttct tccatcgtac
   105121 cgaattctgc catgattgct tgataattac tgatatcata cccattgtca tcattcggag
   105181 actcgtatac tggagaaagc caaattgcat caatacctaa atacgccaga taatccaacc
   105241 tggaaataat cccccgcaaa tctccaatac catcttgatt tgaatcttga aaacttcttg
   105301 gatagatttg ataaacaact gaatggtgcc accatttttg ttccatgatt ttcctcctat
   105361 aaatggatgt ttctattttt tgcttaatca tttattttag tctctctcac taaaaattgt
   105421 aacgctttca aatagctatt gcaccttgtt atcggtaaca gaataaaaca aaaaaacagc
   105481 tgaggaaatt ccctcaactg ttttttgaaa ggattgattt atgcagggaa gaatgctgat
   105541 ttcacaactt ctttataaac ggtgttcact cagctgtccc ttggtattag ctcaaaaaac
   105601 ggcaaaatat aagaaactat tttttcgttt ttttctctaa tactcaggcc agaacgctga
   105661 tttcacaacc tctttatttc acattcaata tccacatgaa tcccacaaat acaaagaaca
   105721 gaccatacat gattggagat acttcttttc ctcttttagc tgctaacatg gtaattggat
   105781 agaagataaa acctaatgca atcccatctg aaatactata agtcaaaggc atgccgatca
   105841 agatcaagaa tgaagggatc gcaatctcta agtttcccca ttcgatttgt cgcaaagatt
   105901 gtgccatcaa tactcctacc ataatcaatg ctggtgcagt tacttgtgaa gtaacaactg
   105961 atagtaatgg agaaaagaac aagcctaaca agaagaaaat ccctgtagta atagctgtga
   106021 tacctgaacg tcctccaacg gcgataccag ctgatgattc tacaaatgca ccaacaggag
   106081 aagtaccaaa taaggaaccc gcaagcatag ctgttgaatc agaagctaaa gctttcccta
   106141 cacgaggcat cttgttgtct ttcatgaaac ctgcttggtt tgctaatcca actaaagttc
   106201 ctgctgtatc aaagaaagtc acaagcaaga atgtcagcac tacgacccac atttgaagag
   106261 aattgatgtc ccctacatgt tttaatgcaa ctaaaaatgt tggtttcaaa cttggtgctg
   106321 cggcaacaat ttcagaaggc attggaatca aacctgtgac cagacctaaa atcgttgtag
   106381 ctgccatccc gatgaagatg ccacctggta cacgccgaac aagcaagata gcagttacga
   106441 ctaatccaaa aatcgtcaac caagtagaac caacgttgag tgatcctaat cctactaatg
   106501 tagattcatt cgaaacgatg atcccacctt cgctcagacc aaggaaagcg ataaatagac
   106561 cgataccgcc agaaatcgca tatttcaaat ctgctgggat cgcatcaatg atcatttccc
   106621 gcagcttgaa gattgtgatc aaaataaaaa tcaaagaagc aacgaatacg ccggctaatg
   106681 ctgtttccca tggaatcccc attcctaaac aaacagaata agcaaaaaaa gcattgatcc
   106741 caagagcagg tgccgttcca attggataac gggctaatac ccccattaaa acacagccga
   106801 tcgcactggc taatgcagtc gcagtaaaca ctgctccttc atccattcca gaagcaccta
   106861 atacagttgg atttacaaat aagatataag ccattgagat aaatgttgta aatcctgcca
   106921 gtacctcacg ttttaccgtg gtgttcaatt tttctatttc gaagtaggaa agtatttttt
   106981 ccttcatctt ccatccccct aaatccgaac attataaata aagtccgtta aaatttcgat
   107041 ttattaataa aacaacgtgt tttatcatat actaaaacaa aacataagta aacaaaaaat
   107101 tcggatttta agcaaaatcc gaacgttcca tctgattaaa tccctttatc tcaaagttca
   107161 tgaacattca ctttggatta caagaatttc tttattgtgt taataaagtt tcttcattct
   107221 agtctcaaaa atcaatagtg tgatttgatt ttaccatttc gtttctgttc ttctttgatg
   107281 aattcttttg tatcgacagg attcagatta tttagtccgc caaaacctgt atcgaccatt
   107341 tttccccagc cttttgtctt cttttttcct gatttgagat tctttgctcg aagcttctca
   107401 ctatgttttg ctcgccgata cttcaaataa ccttctaatc ttcccattag atccactgtt
   107461 tttcctcctt tttattcaat cagacgactc agcttttcct ataacaaaat aattgccttc
   107521 agggtcagaa aaattgaaag tcaagatgcc attgttatct gtgatttctc ctggttcttc
   107581 catgttctcg tagatagttt caaattcatc cgtaaaaaat actaaagaag gcggtggtcc
   107641 taatacctct ggtgaaaact tctgcacaaa tacttttggg aatacgccta attctaattc
   107701 ttttgagatg ctgagtacaa tactcttaaa ttcttctggc aattcgattg tttcagaaat
   107761 ttctgcacca attttttcta caaagaatcg gcaaatcatc tctacgtcat tgacataaag
   107821 catcacacgt gttttttgta tcatcatttg acccttcttt ctatttgatt ttctttcctg
   107881 tctataaact gattccatta tatcacgaaa gcgcaaacac cttgtgtttg atactattca
   107941 agaaaaataa agcaatagtt tctaggattg ctttcctcca caaacttttt ttacaaaaaa
   108001 aaaaacggca atgaatgccg ctcttcttat ttcgattctt ttataattct gcttctgatt
   108061 catctttggt tagtgtgtgt ctaacactag ttacgccaaa tgtttgatcg attttttcct
   108121 tcaacgcttc gattgcctgt gcgccacgtg ccgcttgttc agcattgatg gattcaatga
   108181 ccagcaccgc tgcttgtgtt tcttccgtca gcatcgttct ttgggcttca cgccagttga
   108241 gacagcgaca gatcgctcct tgttcatcat agtagatgat ttcttccgga agtgccggag
   108301 catcggaatc tgcacctaaa ggcaggaatg attcgccacc ttgggctttt cctaaatgca
   108361 gatttcctgc gatcttttcg atatcttctc cgccgcaagg tacgccaaaa gacaaggaaa
   108421 tactattata gatatctaca agcggattga ttgggaaaaa ttcccgttct tgatttgcac
   108481 gtttcagtaa agcttcaata gaagaacgtg cacctttttt agtcttgaat gtggtaaatg
   108541 cctgacgcca ctgagcaatg acttcgtttt ggctgaatgt ttcttctgta aggtaatttc
   108601 ttgcttcttt tgctgcctca ttcaataatt gatgatacgt ttcttcactt tcttttgtta
   108661 cgtggttatc gataccattt acggataaga tttcgatggt tgcttcagga aatacttccc
   108721 agaaattggt atccactatt acttttttca tctgttcaca cctcttgatt agaataattg
   108781 cttgatgaat agatagtctg tttggggatc atctcccata taaaaaacat gttcgctgta
   108841 tttgataaat ccttttttac gataaaaagc gagcgcaaca tcgttgtgtt cccaaacacc
   108901 gagccaaatg gctgtttttt gcttttcttt tgctttttca atagctgtat ctagtaaaaa
   108961 tgtaccgata ccttgatgtt taaatttttt tcgtacatag attcgctcga tttctaaaaa
   109021 atgatcagcc atttcctcag attgactcgt tcctgtattt agtttcaggt aacccgcagg
   109081 ctcttgatcg atactcacta ggaaaaaatc ggtttcttta tcttttagct cttctgtaag
   109141 tttttctagt gcataagctt gtgtcaagta atcagctaaa tgctccggtg aattatcttt
   109201 tccaaatgta tctgtaaatg tttcgatact aatttgttgt agtaagtcta catctgaagg
   109261 cgtcattttt cgaatttcgt atttattcac ggcttcttcc tttcaataga tccttttatt
   109321 gccttttttg acaaaattcc aatcttcgct aacattcttg catactttat ttaaaagata
   109381 ttccaattgt tttgcttctt cgtcagaaag accatttaat gcgactgcat tggagtagtt
   109441 gttttctcga atgatgaaag gatagatttc tgctcctttt ttagtcggat agagtttctt
   109501 gattttttta ttttctttat cttccaaacg ttcgatcatc ccattggatt ctaatttctt
   109561 gattgctcgg gcagtcgttg tacgatctac tttgatcatt tctgctagtt tttcttggat
   109621 gattccagga ttttcgcaaa tacgtactaa ataaagatac tgtcctcttg ttaaatcgac
   109681 ttctttgaat tcgatattgc taatagaatc tagcgctcgg gcaatcattc cgatgtctcg
   109741 aaggatttca gccatttcat cccaccttta ttttgtttgt aagactagtt cacctctttt
   109801 tgttgcaaat gcaactattt tcaataaaaa aatcaagttc ttttttaata actagtaaag
   109861 tatattcttt tcttctttta cgaaaaagct caatcacaat agatctggtt tttgttttct
   109921 aaaataagta actgtttctt cgttgttcgc ttttctgata gctttggcaa ctcttctata
   109981 ctaaaaaatc ccatgttgga agtttcatta ttctcaataa acttggcctc ttcaccgtgg
   110041 atcgcacaag caaaaacaag tttataatac tgaaaaagct gtggaatatc tttttgttta
   110101 ttcgtatcaa aaactgctcg caactgagta gtttctactg ttaatcctgt ttcttcatag
   110161 acttctttac gcacattttc ttcaggagac aatcctattt cagcaaatcc accaggaagt
   110221 gaccattctt tcgtccgttt atcttcgatt agtaggacct tgccatcttt tttgatatag
   110281 gcacgaacat ctacttttgg tgttggatgt ccttctccaa tcgttgtgag cgcttttatt
   110341 tcttcgaaag tttcttttcc tatttcactg attagttcca atgaaatcgt ccggatctcc
   110401 tcaaaacgct ctttatcaaa tacatctttt ccataatata gaccagcttg agaaagtgcg
   110461 agtagtcttt tgtattgagc caacttcttg ttcattctct tcccttcttt tttagcaaat
   110521 gtatgactat gtaatcaagt atagaagact ggtttaatta cggcaaataa atataatgaa
   110581 atctgcaata aataaaagaa tgttaaaaaa ctcgagaaca aaagacattc gacttctctg
   110641 gggctgtgaa taaatggcgt tcaaaagctt gcatctgcgg taataagccc caccaaacga
   110701 aaaatatgac gagctattct tgtctggctg ttcttattaa ttgaggcagg acagcttttt
   110761 cacaacctcc ccactaaacg gtgttctcct accaactcct cggtcacaag tcacaatatt
   110821 catcaaacat gagaagctgt ttttttgaaa ttgctccttg tgactcggag ctgaacgaca
   110881 ggctcacgac ctctcggtaa acagcgttca aaagccaatt tttcgatatt aagccatttc
   110941 tttgttactt attgtcattg atttcttttt ctaatttatc caatagtgga gtgtaatcca
   111001 cttgagtata gtctgttaca tcaaattcat atagtgttcc taactggaat ttgtcatatt
   111061 ttcggtcggc gatgatcttt ttgaatgctt ctttcgtaat atgattggtc cctttcgttc
   111121 gatcttccaa tacgtcacca tagtgataat gatccatgat atagctcaaa tgacgatctg
   111181 attcacgatc acgtttgtac cgacgttgcc ataacacttc aaagtctgct gttaggcgaa
   111241 tcgtgatcac ctgatatccg tatctatctg ctaattcttg gagtcgtgct ttttgcttat
   111301 cactaaaagg atactcggac acaatcactt tctttcctgc ttccatatac aaatcaagtg
   111361 ctttgtaata gaaaggataa actttcgtcc tttcttgttc cgcccgttct tccaaattgt
   111421 taaacccgat ggattctgca tagtattcct tgatttcatc gagcgtgatg gcatacatat
   111481 ctggaaatcg ttcccgtagt ttattcataa gatatgtttt tcctgtacca ggactaccag
   111541 ccagaagaat gaaatacttt ttcatctcat ttatttccta agttaattgg actttccaag
   111601 ttcataaaca gtccaatctt atgcttgaca atttctttta ctgcttcatt tgctggaatc
   111661 acattatggc gaagagactt gttgatttct gtttcactaa aggtttcttt agctactttc
   111721 gtccagttga ctaaaagctc cgttccaaca ttgaatttgc ggatcccgtt attgatcaat
   111781 tcaggataat cttcttcttt cacacctgtt cctccatgga taactagggg gacatcaact
   111841 actgcatcga tttctttcag caagggaatg tttacttctg tttttgattt gaattgtcca
   111901 tgattcgtac cgatagcaat agctaatgca tccacgcctg tagcttctac aaatttcact
   111961 gcgtcttccg gtcttgtata taccttgtca ttttcagcga catggattcc ttcttctgta
   112021 ccgccgattg ttccaagttc tccttctacg gaaacaccgt gcgcatgggc atattctact
   112081 actgcttttg tcttcaggat attttctttg aaaggcagat gggacccatc atacatgaca
   112141 gaagtatatc cgctgtcgat tgcttctttg atatcatcaa agtctcgggc gtggtctaag
   112201 tgcaagactg catcaaccat ttcttcttct gcaatagctg tcattacatt gactaacaca
   112261 tgcatgccga tatatttagc ggtatcgaca cttgtttgaa taatgatcgg cgaacccatt
   112321 tcttttgctg cgcctagcat agcaggaagc atttctaggt tatgcgtatt aaaagctcca
   112381 actgtaaaat tcaactcttc tgctgttttt gttacttctt tcaatgttgt atacatcttt
   112441 tattgccacc ttatcttttt atttgtttcc tttgatcgtt acttgttttg caatttgtcg
   112501 catctcatcc attttgccca tgtagtaatc gatcccttga tcatcaccag cacgagcagc
   112561 atctgcacgc ttctggttat agaggctcat cagtttttta tacccatctc cgatcgtctg
   112621 tttattttcc aaactctttt ctaaatattg gatggcttga tcgttcacat acaattcaga
   112681 aaatttaagt ccaacttgtt cataaagttt cgctaattta tgcttatctt gggtagtgga
   112741 aatctcttgt ttcaattgtg taatctctga ttgaatcttt tcggtcgctt ctggcgatag
   112801 ggctttttct tcttttgcca gaactttttt cggttctttt tcttttttct taaaaaatcc
   112861 aaacatcatt ttccctactt tcaattaaaa tgctttcaaa actgggctta agatccaggc
   112921 atataagagt gctgcggcta ctgtatctac atcggttgct gtagcattga tgaatcccat
   112981 cgaattaaag atcgttacta gcaaagcggg caataatgta ataaagaaac catgagcaat
   113041 accgccaatg atcgctcctc ggcgtccgcc aactgcgttg ccaaatatcc ctgctgtccc
   113101 tccggcaaag aaattggtta gcataccagg taaaatcatc gctaagccga acatgggcaa
   113161 agtaaacatg gcaataatcg taccaatcgt tgtcgtaatg aaacctaaaa tgacagcatt
   113221 tgggctataa ggaaagaaaa ctggacaatc taaggcaggg atcgcatcag gaactaattt
   113281 catagctatc cctcgaaatg ccggcacgat ttcacctaac agtagacgta caccagctag
   113341 caatacatac acacccacta cgaattggat ggcttgtaaa aaggcaaaca tgatatagtt
   113401 ttgatctcct gataattcag aagcgaatgg ttcgcctgca aataaaacag tgatgatata
   113461 tagcgggacc atcacgacca tgacagacaa ataagtatct tgcagaaatt cgaaatgtgt
   113521 cggcaacttg atatcttcga tcgacttttt attttcgcct ttctcaccaa aaagcttagc
   113581 aacaccggct tcaaataagt acccgatcgt acaaaaatga cctaaagcaa tatcatttga
   113641 tccagtgatt ttacgaatga tcggttgcgc tactgccggc atagcaatgg cgaaacaagc
   113701 tccgataaaa tcaccgacca agatcaatac gatccctcgc agaccggcaa aatagccaaa
   113761 gactgtcgtc atcgttgcca tccataaaat tgcttgacca gttaaaaaaa tgtacttcca
   113821 ttttgtgaaa cgagccaaaa taatattgaa tacaaaaatg gctaagaacg tcagtgcaat
   113881 atctctacct aaacccaaat cattcattgc ttgaccattg atagattcaa tagaagggat
   113941 gatcccttgc atatgaaatc cttcagtaaa gattttcccg aaataagtta aacttccaac
   114001 gatgatgctc gaaccggcac tcaacacttg aaatcctagg agtgtcttta acgtgccaga
   114061 gatgacttgt cctgctgatt tcttctgcag tagtagaccc aacatagcaa tcaatgcaat
   114121 ggtgatcgat gcctgagtca aaatattttc gatgataaaa ttgataacgc ccatgttttt
   114181 accctctttt ctttttgtat ttagataact cccttatctt gcagaactgg ggtgattttt
   114241 tcttcaattt cattttttga aacaatattt ttcaaataga tcatcgccgt tttaggatca
   114301 actgcgaact tttcgaactg cgaacgaaaa ttttctgctg tgatgatcac atctggtttc
   114361 atggaaactg cggaagaaat atcacaatgg tccagtttgg cttctactcc taatttgttc
   114421 aaaacatcct cagcagacat ctgtgctgca aaactacttc ctaaacctgc accgcatacg
   114481 aataaaatgt tcaatttgtt catctttgtt ctcccccgta tcatttatta tttctcaact
   114541 actgaaaaaa gcagttgttt gaaatcttcg atatttgtgc attcaatcaa tcgatccaac
   114601 ttctcttcgt tgttgatcaa ttcaattagt tctttcatga tgttcagatg cgagtaggag
   114661 tctactgctg ccaaacaaaa aataatcttt actggatcca tttcaggatt accgaaatcg
   114721 attggttgct caatcgtagc tacgctgact cctaatttat tgaccccatc ttctggtcgg
   114781 gcatgggcta gtgccatgtg tttgccaatc acgatatacg gtccgtaatc attcactgca
   114841 cgaatcatcg cttcgacata gcgctcttcg acaatgtttt ctttaaccaa tggtctagca
   114901 gctagttcaa tcgattcctc ccaagtagtg gctttttctt tgatcatgat attgctgtcc
   114961 gtcaaaatat cttttaacat aggctggatc tcccttttgt tgatttctaa attgtttgtt
   115021 tcgaataatt tttctaactt gccatagatg attcgatcta ctcggccacc actttctttc
   115081 atgacatcta ttatttgagt gaataactcc gtcgattcat gactgttagg ctctaaccgc
   115141 tgtagttctt catttctttt caaaaagtct tctataacca agatattcgt ctcagttaaa
   115201 atcggatcga caactaaaag cggcttattt cgataattca attgaaaggt gctgaaaacc
   115261 agattgacat ccaatttatc tactaattcg atttcttttg aacttaaaac tgcagtaatc
   115321 tcgatctgag gaaacttttc tttcagattc tctgctaaca gatttccagt agccatccca
   115381 tggttacaga caacgactga tttataaaca taattcaagt ctcgcttgat tacactggcg
   115441 atcgtcgaaa agtggatgac aagaaaagct atctcgtcct ccagtatctt gccaccaatt
   115501 acttcttcga tcgtaggaac aaaatgagtg actgcgcggt agattgggaa ataatttgtt
   115561 cggatgtttt ctttcaatgg attcatgact tggatatgat tcttgattct tacaatcagt
   115621 gcagccatgt gcttatagag attttcgaat aaagcttctt cctttagatg gaaaggtacg
   115681 tgtgtctcgt tctctacaaa ttggatcaat tggatcgtta gtaattgagc ttgtacccac
   115741 tcgattgaat tggagatatc tctagcattg aacgtctcaa tagtgaaacg aagataattt
   115801 ctttctactt gcgggacatt gtccaattga aattcctcga tcatgtggtc aataaatgca
   115861 gaaaagctac tgtcttttat ttctgtattt ttccaattaa tggcagagat aaattcatgt
   115921 ttcctgattc gctggatcca gatcaatgta aaaagcagga tttgtttttt ataaatatca
   115981 tcttcttgtt tcaacaactt attggaatag atctcctgta tttttttgat ttccaccaaa
   116041 ggaaaataat ggagaaagat tttttgagcc ggtgttaatt gtgcatcttg attcataaag
   116101 aagtcggtca ttcccagatt ctgattgata aaatcataga tcatcgtacg gatagatcgt
   116161 tctgaacctt tataaaccag tccttgcttt ccataactga cgatctctat cccataactg
   116221 accagtgttg ctcgtaaccg tctcatatct tcatctaatg tacttttaga gatttgaaat
   116281 tcttcttctt ttttgtttag atggatcggg attcggctgt aagcaacggc taaaactaga
   116341 tcaaaaatac gttcgcgccg attcaaaaag ccgtctttca catcttttat ttcagtttct
   116401 aatcgagctt gcttttcctt ttccagcttc aacaaaaaac ctttgttgcg aattgtacgg
   116461 atctccggaa gctttttact gctcaaccag atattcgctt caagaacttc ctgacggatc
   116521 gtccgctgac tgacattgaa ctcacttgct agatgttttg cttttactgg atattgggct
   116581 gtcatgattc tgtgaagtat ttcaattgtt cttgttttca tagaaatgat ctccttctga
   116641 tttcaagtat atggttccgc ttacataata aaaagtagat atttctgcca cttgaagtgg
   116701 aaagaaagta agcaaagcaa acaaaaaata agccatatgc tttttcatct cctcaacgaa
   116761 aaagacatac gcctattatt acaaaaattt tgcccatcta tacaaaaaag aggttgtgaa
   116821 aaagctgtcc tgcatcaagt aataagaaca actaaactaa aatagtgctt cctatttttc
   116881 gtttggttgt tcttattatc gcagatgcaa gcttttaaac accatttagt ggagaggttg
   116941 tgacagagat gttcagcctt gagcgataag aagcgatttt gaaaaatcgc ttcccatatt
   117001 ttacaaaatc gtgccttatt gccgataggc tatctctggc acaccgttta ttcagaaaaa
   117061 ggagctgcga caaggctttt gtcacaactc cgttcataaa tatttcctgt caatccagca
   117121 taatcggctg aataaaatcg gcttgccatc ttttttcttt ctcagaaaaa tcaaaatacc
   117181 atatctgaga aaaatactgt cgttgtgtct tacttcctga gatcaatcgc ccatcttttc
   117241 gatcgactga ataatcacag catctgaaat caattcggat ggcaaaacta ttttcgtgga
   117301 tctgtcgata atttcctact tcctgaatag ttattttttt agtatgattt cttacaccgt
   117361 ctgctttgtt tttttgcaga actttctgat gttcggcaaa cagcttgtct gtataacagc
   117421 ttctggcttt ttcaggagtt tcttcttccc aagcggattg gatcttcatg aatatctttt
   117481 ggatttccag aaactgtgct ttcttttctt tagccgttcc tgacatgcgg gacaatatct
   117541 ccgctttcag ccttttcttt tgtcttttat tcttgacgat agaaaaagca gaaacccctc
   117601 ctactgacaa aacagctaat gcaagaaatc ccgtttgctc ataactagaa ggacctgtac
   117661 ctggaccata atacccataa gaatctctgc cgtaagaacg actgccaaaa taactgcccc
   117721 catatgaacg accaccaaat gaacctctgc ccgaacttcg accgctagat gtacctccac
   117781 catgaccacc cgcgacagcg aatccttggg tcggcagagc aaacaaacat aggcccacta
   117841 acaaaatgat tgctaaataa ttgatttttt tcattgtctt cctcgttatc ttttattaca
   117901 aaaaactatt tttatgatag ccttgctaaa aggaagagtc aataaccaga tgcataaact
   117961 gtttttttag caattttgtc ttatttagtc attgagtaac atcggacaaa tgtatgtgtc
   118021 ggcagtccat aattcctcta tcttcagcat gaacaagctt gcagacaaga gatctgcgct
   118081 tcctccagga gagatttggt tttcctgaca aaagtgcaac agtgctgtaa atggacgatt
   118141 tggtaaagca ctttgactag cagcatgagc aagtttttgc atttccacta acgttttctg
   118201 atcactgcga tgcaatacgc atgtgtcatc tagcgaactc atcaaaacta acaacatatg
   118261 catttgtttc tgtacatatg aatcattatc tagctcctta gctgcttgaa ttgcaagcct
   118321 gatatgcgga taccctaata tcgcttcttc atatgcacca tttacgccat atttttgctt
   118381 caccctatga ccatgagtgg tttttttatg acgatatttt gtatcaggaa aagcagcaag
   118441 cttgctgaca tcatcaagta ttttcgataa agaaaaaggc tgttccatac tgattttttg
   118501 tgcaatgaca ctgatcaata gccccattgc ccaaatcgct cctttatggg tattgatgcc
   118561 atttgtagca atcagcattg ccttttccgc ttttcgccca atctcagcaa ttctttctct
   118621 taactcctga tcaatagcat gatgccatgc tatttgagcc atttcttcaa aaaaaggagt
   118681 tagcgtctta gcagacttaa gaaataaagc atagtccata tcggaatgtg cacccgcatc
   118741 cagtgcatcc actaatccag gttttggact taatgttact tctgcgatca atgcttcctc
   118801 taccaacgca gcgagttgct gagtcactgc tttttttcgt tcgtcattta tcatgacact
   118861 cactccttct tcctactatt acttgctgaa accttttttg atagctaccc aaatgatatg
   118921 aagtaaccag cttaaagcaa atgcacaact tgccgtcatt agataagcta caagaatcat
   118981 gactcctgaa ggtaactgca gccaactatc tttaaacaat aataacagta cttggaaaac
   119041 aaatacattg gctaaatacg tacgataagc ataaacagac aaccatttga acaatggcaa
   119101 ttttggcgaa tcgtttacaa tcattttgga agcgcctatg aagacagcaa agatgatgac
   119161 taaactgtat aaactttgga tcgtattcaa gtaaggtgca ttcgcaaagc tcaagtctcc
   119221 tggatgtgcg agcaatgaac ggacagaaaa gaacgcgata actaaggcaa caggtaagaa
   119281 aagataacgt actctgtcca aatattgata gactttttcg tgataaacaa atgcggctac
   119341 cccataaatc atgaaactag caacaaaccg atctaataag taccagctgt catgataagg
   119401 cccagtcaat acttgtgttt gatagaacag ataccatgcg acatataaaa tcgttgaacc
   119461 aatcaatact ggccatacat attttttatt agcaaatact ttgtaaccga gccaaacaaa
   119521 aaacggcatg aacaattgga tctgcagcat cataacggta taccataaat gaggcgctcc
   119581 atcacctgtg acatatttca gtaaaaagct tgcagtatcc gtatacggag tttgttgttg
   119641 gactgctgga aatagccaaa gataagccgt cgtccataga agatacggaa cgactagttc
   119701 aaaaaacttt tctttcaaaa attcccaata agacaaatgc tgacttgttt ttaccatatt
   119761 ataaacaatt gcaaaaataa acattggtgc tgtgtattta acgatgacgt aaaaggtacc
   119821 aagaaaagct gtatttgttg cgctgtggct gtttgccaaa gcaaagctca atatcgtttg
   119881 catcataaca gccgttacag ctgatacttt ctggaagtca cttacgttga ttttgatttt
   119941 tttgttttca aacatctctt tctctctctt tttctttatt accaaagttc tttggttaat
   120001 ttaggtcctt cgactgtttt caatagaatt tttttctctg gctctctcaa atactctttt
   120061 agtgaaaaac cgccttgccg agtcactact tgggtatcga attgctcaaa aaaagcagga
   120121 tgcgattgaa ttacctgaat tggcaattca atcggtgaat ttgcgtacag cagcaaatca
   120181 aaatcactgg tttcttttac tgccggaatc ccagtcgata attcaaatcc taagctgccg
   120241 ccgattcccc atttacatcc tgataatatg tttctagcag catgaaattg ctgataaaca
   120301 ggataatcca tgattttctc ttgtctatac gattcttgtt cgatgatgtc ccacggatga
   120361 atgacttgtt tgacggcatg ttttgagatt tctgttgacc atctctgatt gcgggcaggt
   120421 ccacgtaaac caatcggtag tatttctgcg tgatccgtcg acgcacgacg aactgttccg
   120481 aacatctttt cagttagaac gacccattca ggcaaggtga acccttctat ttcatgttta
   120541 tcaaaaagga caatatcatg tgcttgaatc attttttatg catcccattc ttcgtccatt
   120601 ttggcacgga ctttatttgt ttcgacacgt ccgaatgttt tggctgtttc gtttgtgtat
   120661 cgatttgtca gcatcgtgtc atttgtattg cggacatctt gaatggcttc attgattgct
   120721 tcgatgactt tgctgacatt ttgttctgaa gcagcttggt cggtgatatc ttctaggaaa
   120781 tgatagatcg ctcctagttt tgtataatta ttgatatcgt aagcgatagc tggaactttt
   120841 tcagcagctg cttcgatttc agcaaccgaa cgttttgtca cacgtgcagc actttcttta
   120901 gacatcgctt ggacggtaat ttctttattg tttaaagcaa tcaagcggct tgattgtaat
   120961 ccatgtgcta aaaatgcacc tgaaatagca tttcctgcaa tcaatccaat aactggatgt
   121021 ccagcttgac ggagttttgc ataagcagca gcactattag ccaaagccac atggataccg
   121081 atcaattctt cgttatagcc gtatgcttgg cttggtacat cgatcacaac gatgattggc
   121141 cgtttcactt ttttgtcttt atcttcttcg taaacgtgat ccaaaatttg tcccatgcgg
   121201 aaaccttcaa ctaaaccaac ttcaccgttt cgtacacggt acatcgggtt tttaggatca
   121261 ggtacgattg atgtcacgat ggcttcttct atgaatttac ttgatttacc ataatacaca
   121321 gtactaatag aagaagttgg atttttcatg ccagttagtg ccgcaaacca atcgtaacca
   121381 acacttgctg cagctggttc atttccttct gctacttctg gtaagtcaat tgattttgct
   121441 tgatggttag caattgcttc attgtaatcg tcaatggcca ttggttttga aagatctaaa
   121501 gaatcaagta atgataaata aaatgctgag ctttcactgc gatgcgtgtc ttttcgttcg
   121561 tccattgctg cgatgacagc agctttgatt gcttctacac tatcagtcac taattcatca
   121621 atgatttttg attctacccg ttgacgagat cctaatgtat tccaaatcaa gtctttgtca
   121681 ctagaatcaa attctcgaac gcctgcttct tgttcaataa cttctggtcc attcaaaccg
   121741 actctcgctt tttttgttgc gattaaataa ctcattaatg ctgaagtaat cgacataccg
   121801 ccaaatgatc ctacacgtcc tggaatcaaa ccgatgactg gtacatattg ttttagagca
   121861 atgattacat ttccgatttc tgaaatagat aacagtccgt agtttgcttc ttgcaaacga
   121921 acaccacctg tatctagtac aatgactgga aagatctcat ttcctttttt attttcttct
   121981 aacacatgtt caagtgcagc aacgattttt gcaccggaaa cttcaccgat accgccacct
   122041 tggaattttc cttccatagc gattactact gcttgtttgc cattgatcgt gccacggctg
   122101 acaacgatcc cgtcatcact ttcagggacg attccttgtg ctggtaaact tggcgcgatg
   122161 atttgatcga atggatcaat caattcacgt ccattgtcaa gtagagcgtt cactcgttct
   122221 ctggcgttta attctacaaa actatttttc atctgaaagt tcctccattg cttgcgtcaa
   122281 tcgtaggtac acaactcctg gtgtagcacc gaagtcattg atcacgatat ctgctgaaat
   122341 tggataacga tcaaaaaatc tcgttaatac attgttccat acttcgccga agccatcgct
   122401 tcctgtacaa atttttacag tagattctgt tttttctgtt ggaaacatca agatttccaa
   122461 atctcctgaa ccgaccactc ctacatggat tttcttattg atcggctgtt tcgttggata
   122521 tttataagct aattgttcca tggatctctc ccctttttgt aaaacagagc atacacgttc
   122581 tgcttattcg tctttcttct tccatctggg taaatggcga caaaaggttt ttctcgccaa
   122641 ttttatgacc aagttctgaa tttcattggt ggttcataca ggccatctga ccattcgatc
   122701 aaatcatcga tggtttgtgc agctaataat gaacgtttcg cttcactacg tttgatgcct
   122761 agatcttctg gtaatttcac gatgccggct gcacgcaagc tatctagtga ttctttcgtg
   122821 ctagtcattc caagaggtgt aacaccgcca attgctgcaa ttgctgcttg tcgttcttct
   122881 tttgtttttg ctttgtacaa ataagcaatt ccttcttctg tcacgatatg tgtagtatct
   122941 tcgctataaa tcatcactgg tgcattggct aagcctgctt gtttttgaac agctagtgca
   123001 tctaattctt cgacaaagac tggtttttta tttgaaccat atgtttcaac catttgaaca
   123061 actaattttt ggcctttccc taatggatca tcattgtcgc gaagtgattg ccatgctggt
   123121 gtagaatgac gacgaccgcc aggattatgt cccatgttag gcgcaccgcc aaaaccagat
   123181 aaacgtcctt ttgttacggt agaagagttt ccttcgtaat ctaattgcaa ggttgaaccg
   123241 ataaacatat cgatggcata ttgtcctgca gcttgtgata atgttcggtt actgcgcatc
   123301 gtgccgtctt taccgacaaa aaagacatct gggcgagcag caatatattt ttccatacca
   123361 acttcgccac caaaactatg gatgctttca acccaacctg attcgatggc tggaatcatc
   123421 gttggatgtg ggttcaatac ccagttcttc gcgattttcc cttttaaccc tagtgattca
   123481 ccataagttg gcagtaacaa ttcgatagct gctgtattga atccaatacc gtgattcaaa
   123541 gattgtacgc cgtgttctgc gtagattcct ttgattgcca tcattgccat tagaatttgc
   123601 aattctgtga tgttttgagg atctcgtgtg aataaagctt ctaattgata aggtttatct
   123661 gctttcacga caacgtctac ccagtcacca gggatatcta cacgtggtaa agaatcgaca
   123721 acttcgttga cttgaacgat cacgatacca tctttgaaag ctgcagcttc gatgattgtt
   123781 ggtgtttctt ccgtattgaa acctgtgtac aagttgccgt ctttatctgc tttatctgca
   123841 gctactaaaa caacatttgg aatcaaatcg atgaataagc gtccataaag ttccaaataa
   123901 gtatggatat cacctaattt cattgtgccg tcttcaatca tttgggcgac acgcaagctt
   123961 tgtgcaccag cataagagaa atcgatcttg cttgcgattc ctttttcaaa aatattcaaa
   124021 tgttctggtc gtgagatact agacatgatc aaatgcagat cattcacttt ttctgcatct
   124081 actttttcaa gactttctga aagaaaactt gcttgttttt gattgtcgcc ttctaataca
   124141 actttgtcgc cgggagcaat cagtttttcc attacttcta cgattttttc agtttctaca
   124201 tacttgccat tgagcaagtt gctgattttt tccaatcgct gcgctttttt ttcgcgttta
   124261 gaagcccagt tgcggtttgg tttttccata attagtcatc tccatttttg atatagaaac
   124321 gtggcgtcat caataccatg ttggtctaga ttgatcgtac ggatcccttt atctacacca
   124381 aattttgtat gaatcagctt tgtcaaagta ttgccggggg gaaattcaat cgtcagatcc
   124441 attcctaatt cttttgccaa gtccatcatt tggttccact gcacagggaa agctaggttt
   124501 tccaacaaat ctttacgaat ctcttctgcg tcctgagtgg ctcttccatc cgtatttttt
   124561 atatacaaac atctagcatc agatagatgg acagactgca tatacggctt gaatttcttg
   124621 accgtatcat tcatcaagag acagtgagat ggcacaggga ctttcagcag cttcgctgtt
   124681 tgcgcttggt gccgtttggc ttctgccaac gtaacggata aaccttcgat actcccagat
   124741 aacgtatgtt gcatcggaca attttcattt gacagataaa ctggatggtc aggatcaaat
   124801 gtttttgcta caatttcctc agcttcgctt ctcgtcacac ctactactac gcccattgca
   124861 taaccgcttg gataagcttc tttcattaag actgcgcggt gatagactag ttccgctgca
   124921 ttctcaaatc tcaaagatcg acaagcaaca gctgcacaaa aagcaccaat cgaatgtcct
   124981 gctgcaatat caggctgaat accgtttttt tccatttcat ctaaataaaa tactgctttt
   125041 gtcagtaatg ctagctggat aaaaaccgta tcttgatagt tttcttcttt atcaactaac
   125101 cgataccccg tcacattttc taaacgttcc atgtacattt cagggatatc cgctaacatc
   125161 cctaacttct gactgccttg tccaggaaat aagaaacctg tactcatgag cctcgcctcc
   125221 tcagcactta ctttttccac tgctatctta gtcaatttct gctataataa aaaatgccaa
   125281 aaaaagaaaa aaccataaca aaaaggtatg gatgggatgg ataattatga aattgcttca
   125341 tctgcagtat tttaaaaaag tattcgaaac aaaaaatgtt acccaagcag ccaaagaatt
   125401 atttatttct caacctgcct tgagccgtgc gatcaaacat ttggaaaacg aattaggtgt
   125461 ccctttgttt taccatagcg gcagaaacat tgagacgacc gtttatgcag aagaatttta
   125521 tccatatgca gtcaagacat tagacacatt agaagaagga atcaaattat tgtcttcggt
   125581 caatgagaag atcgttactt ccgtcatatt gtatttagag gtagcctctg tttctattcc
   125641 gaacttggtc cgaattttta tggaaaagca tcctgatatc caattaacga tcatgcaaca
   125701 tcatttacca gatgatatta ccgatcctgt actgtacatc acttcggaga tgaagcctgg
   125761 catgaccaat attcctatca tgaaagaacc tgtttatgtc gccattccta agaaacatcc
   125821 tcttgctaaa aaagaacatc tgcaattaga agatatccaa cgcaccccca tcttgatgct
   125881 gtcaaagagc aacgccttcc gtcatacact ggatgcagca cttgaagcga aaagtatcga
   125941 attgacgatc agttcgacga cagatgatcc tgcgacatta cgttctattg tcaagcaagg
   126001 attagctgtt agctttttcc caaaagtttc ttggtcttac gataaaaatg atcctttcgt
   126061 cttgcgggaa atcaaagatt tgcccttgac acgaacaatt tatttatctt ctagcttcac
   126121 agaagatcat cctttgatca aaatgattgc aaaaacgatg cgggaatttt atttaggaaa
   126181 ataaaaaaaa aagagctggg acaaaattct tgtcgcagct cttttttcga acaaacggtg
   126241 ttccagaagt aatttcttag aaaataagcc gaaatttccc aaaaatttga gaagcaattt
   126301 tcgtaaattc cttcttattt cttgaagcta aacatttctg tcacaacctc ttctctattg
   126361 tcctagacat tcattgcgtt gatttaaaac ttccatcaat caaatctgct agttcatcta
   126421 gcttttctat tttacgtaga tcaatagaga tccaatgttc tttattcatg tgataggctg
   126481 gaaaataccc ctcttttcct cgcaaaattc cgccaagttc aggatcgacc ttcaaatcaa
   126541 gaatattgat gatcctatgg tcacttgcat catcatagat tttttcttct ggaacagaca
   126601 tcaggacccc aaaccatttt ttgctttttt gatgtctgaa tacgcaataa tcaggaaatt
   126661 ttttaaaaat atattctgga gacaaattgt atgtttcatt gatgtgatcg attagttctt
   126721 ttttcgttag catctgcttc catctctttc ttattgattc gctttattca aagataccac
   126781 gtaagaatag aaaaatgaat acaagtagtt gctaatcaaa tacttcgata tttttctttt
   126841 ttatcaactc ttaaatgttc aatccgcctg tgttggtctt gctaccatct actattaaaa
   126901 tgtttattat tgtttgccca cctatttttt gattttagtg gtatcatttt tcaagttcat
   126961 gatgaaattc ttatcatcag taaatgctcc agaaaaataa acaatgattg aaaaatcagt
   127021 tgaaacttga ccaccgttta ttttctccgt attcttagaa tagaagggag tctgattgat
   127081 gtattcacta atgaaaaaaa tcattaccga aaaagatatt cgacgtcatg tttctttagt
   127141 agaacaattg ctgaatcata caaagataac cgtaaatgaa ttagctgaaa tcatagggac
   127201 aaccgaacga acgatttttt ctgaccttca atctattcgc tctcagctgc ccgaaggctg
   127261 ggacatcatc agcgatcaag caggaatcag tttgcaaaac cagcaaaatt tattaacaaa
   127321 tgacctttgg gagatttttt tcaaacaatc agtcagtgtc gaactgctga aaaatctgct
   127381 ttttacaaaa aaagttgctg tccctgattt tctagccgac catgggcttt cttatgggac
   127441 attgaaaaga catgtgacta aaatcaatca gcgtttagca agttacgact tgcagatcga
   127501 tttgacgaaa tatacagctt gtattcttgg aaaagagcgt gcgattcgta ctttttatca
   127561 tcgattgctg attcctttca ctcataacaa ctattttttc gaggattatt cgatccatga
   127621 atcccattat tttcaatttt taagaaacct cagtcaaact gaactagcgg ttgaaacaga
   127681 agagattttc ggaacatgtt ggttctttat caatacgatc cgtataaaag cgaattgccg
   127741 attagattct tctatccata ccaacagcac actctcctcc ctgtatgact ctgcattgaa
   127801 aaaattgtat ttaacggaag gtatttatct taaagacact gagctttctt ttgcttcttt
   127861 ctgctttctg gaaagttgga attacaacaa taactatgga caagaaaccg ctcgctgcct
   127921 gcatcattct ccatttttag aggtcctcga aacgtttgta gaggaactag cttcagagct
   127981 gtctcttgat caactaaaaa aaacatctct gactgataac ttggctctcc tcatattaaa
   128041 atatcatgaa tcgccgatat tgattgaagc attggaccgt caataccatc gttttttaga
   128101 aacatatgat cagcaatatg cacacttgta tcaacagaaa gagaatttac tgaacgatct
   128161 aaaaaaagaa atagaaatca atgaaccaaa ttactttctc caactcttgt ctctactgat
   128221 ccaacaaacg attttttcta tcaaaccgaa tttgttcaat gtctatttta ttttccaagg
   128281 agaaccttca tggaaggcgt tcttgcagca ggaattaaaa gattacttag gaaaacgtgt
   128341 ctgcttctta cctatcgaac taaccgatct ttccactatt tcttttgaaa aaacagatat
   128401 cttgatttcc aatttccctc tagattctct agatatccct attgtataca tttcttctat
   128461 tccaacgaaa aatgagctca atcgtttgac tgaactcact ttcaaaactt ttttatagta
   128521 acggctagcg actgtattct ctagctgttt tttctttttt gcgaaacagt ttgttcatga
   128581 tccctttttc tatttctaca actaagaata gaagaatcac atttgctcca atcaataact
   128641 gttgtgtcat cgttaaactt actgtaccga tcagctgctg gccgactggt agaaaaataa
   128701 ccatcccttg caataaagca aggataccta atgaaagaaa aagcgctttg ttttgcaaaa
   128761 gaccttggtt caatgacggc ttggacaact ctctgcaatt gatcatgtaa acagcttgag
   128821 ctaagacgat attttgcaga agaatggttt gctgtaagct ttgcccttca aactgcatag
   128881 ccaataaata ggcaggaacc atgatcagta gggagacata gatgatccga aacaaatgat
   128941 aaccagatag gattccttgc tttggatctc ttggtgggcg cttcatgatt tctggatctg
   129001 gcgactcgaa ccctagtgca taagataaag tgattgtcgt taccatattg acccataaaa
   129061 tctgtactgg ggacaaaggt agcgggcgat tcagcataag tgcccaaatc aagatcaatc
   129121 cttgagctaa tgcagttggc aagaagaaat tgatggtttt ttgcaaatta tccaaaatcc
   129181 gccggccctc ttttacggct tttgcaatcg tatggaaatt atcatctcct aaaaccatat
   129241 cagctgcctg tttgcttact tcactacctt tgattcccat agcaattcct acatcggatc
   129301 ttttcaaagc aggtgcatca tttacgccgt ctccggtcat tccgacgatt tctccatttt
   129361 tctgcaaagc tttaacaatt cgcagtttat gttctggtgt cgttcgagca aagacatcga
   129421 ctattggcac ttgctgaatc aactcttcat cagacataag atccaaatcg atcccttcta
   129481 aaactttggc agtatgtttt aagccaattt gttccgcaat cgcttttgct gtgtctttgt
   129541 gatcccctgt aatcattttc actgagatcc ctgcttgttg gcattccttt acagctttga
   129601 ctgcactttc ttttggcgga tcgatcaatc cggcgatccc tgcaaaagtt aattgggtta
   129661 aagtctcatg cgtgagttcc tgtttcgaat ctactttttt ataagcaaat cctaaaacac
   129721 gctgaccttt tctcgcaaat tctgcagctg tctgactcca tgcttcttgt tctgcagaag
   129781 aaagagttga tttagcaaat aatacttctg gtgcaccttt gacgtaaatc accgctcctt
   129841 tttcctccgc atgcatcgtt gccatatatt tgtattcaga actgaacgga atctttgctt
   129901 ctattttttt caaaggtaga ttggctgttt ctgtgtgtcg aatcagcgca acttctgtcg
   129961 gattgccact taaattttct gttttctgtt cttcttttgt ttttaattcc tgacagtttt
   130021 tcataatgga caacacgcag gcttcttctt ttgcagctac atccacaact gtcatttcat
   130081 tttttgtcaa tgttcctgtc ttatctgaac agatcactgt catagaacct aatgtttcta
   130141 ccgaaggaag tcctttgatg atcgcctttt cttttgccat ttcatgtact ccaacggata
   130201 gaatcatggt caaaacagct ggcaatcctt cgggtaccat tgacaccacc aaagcaatcg
   130261 tagccgaaag aaggatatgc caatccatac catatcgaaa tgtcgtaaaa ataactaaga
   130321 ataggctcaa acaaagaatg ccttgaaaaa tttgtttgtt taatcggttg atttttttaa
   130381 tcagaggcgt cgtttgttgt tcgaccgatt gcaatgcttg attgatttta ccgatttctg
   130441 tcgtgtttcc tgtttctaca acgacaccga ctgcagaacc agattgtaca agcgttcctg
   130501 aaaaacccat atttttctgg tcgccgatcg attcttcttc tgtcaaaacg gcatgacttt
   130561 tttcagatgc ttctgattct cccgtcaaaa tcgattcttc cactaataaa tcatgtgctt
   130621 cgattaatcg gatatctgct ggaacgacat ctccggcacg taagacaatg acatctcctt
   130681 ttaccagttc tttcgcaggg attttttctt gcatcccgtt tgatagtact atcgcttctt
   130741 gtcccatcag ctgcttcaaa ccattcaatg attcttccgc ttttctttct tgccagtaac
   130801 taacgagtcc attgacgatc actacgaata aaataatact tccttcaata tattcactag
   130861 aagcaaattt caaaaaagag gcaatgatca acacgatcat cagcagatca gtaaaatgct
   130921 ttgctatttt tttccatcgt tttgtctgct gccttgcttt tatttcatta tatccttgat
   130981 cagtcaggcg tttctgtcgt tcttcttgcg acaagccttc tgttgatgtt tgatagttta
   131041 caatacatct tctaccgtca atctgtacca gttcatccta tcccctcctg tttaattgat
   131101 actgttatta tacgcaggga agttttttca ggcgtatcga ttatttcagg ggggtctgaa
   131161 ataattcgtt ttgcaaaatg tatctgggcc taactgatat ttctattgct tattctttta
   131221 tatacaaaat ttaagaatac aaaccagata accaataaaa aaggaataaa gcgtgtcgtg
   131281 ctttcgaata acaagctgaa agcaattgaa gtaaaaaaca ccaacaaagc aagatcttta
   131341 tatctttgtg tagtgttccg tttcttttct ttaataaatt gaacatgtgc acacaagatc
   131401 gaagaccaca caaatagaaa acaactcgtt gtcatgcctg ccaaaagctg aaaaaacaat
   131461 cgactatcag ctacaaaaaa atgtagacaa agaccggcaa aaaataacat tcctgtaatt
   131521 aaaataccgt gtaaaggtac gcctttctta gaaagcgcac aaaaccaatg gggcaaactt
   131581 ttttcttttg ctgtttgata taaaatcctg ctagtactgt agactgcact atttgctgag
   131641 gacaaagaag caaccaaaat cattagattg acaattgctg ctccgccttg gcaatggatc
   131701 acttgcagca tagtcactaa aggactttct tttaaatcta aacaatgcca tggaacaaca
   131761 aataaaatcg acaaaatcgt tcctatatag aaaaagagaa tacgccaagg cagacagttg
   131821 attgcttttt tcaaattctt ttgcggatca cttgtctcgc caacggttaa gccgatcatt
   131881 tcaattccag caaaactgaa taaaaccata ggaaatgaga ctaccattcc agcaaagcca
   131941 aacggtagta attcatcgat ctgtccaaaa ttttctttga ttccgataga ctgggtatga
   132001 aaatctgaga cactcaatcc tatacccaat aagataaaaa ggaaaatccc caagatcttg
   132061 atgattgaga aaaaagattc caattcacca aaccacttga ctgcaacaag gttgactgcc
   132121 attaagatca ttagtgcgct acctccgctt atcaaagctg gtacatgtac aaaccagaaa
   132181 tggatataca atcctattgc tgttaattcc gcaagtccag ctccaagcca gcaaagccaa
   132241 taagtccaat tgacaaaaaa tgcccacttt ttgcctaaat aatagtcaac gaaatcactg
   132301 atagagttaa atgtactatt tgctaaaaat aaatcaccca tggcccgcat caaaccataa
   132361 atagccaaac cgcatatcaa ataaacgaga ataacagctg gccctgctga tgcaattgcc
   132421 tttgctgaac ctaaaaataa tcctgttcca attgcgccac ctaatgcgat taactggata
   132481 tttcgattag ttagagtccg tttcattgcc ggtttttcca tcaagttcac ctttttcttt
   132541 ttcaagcagc atggcgactt cctgttccca agaaggtttc tttatttttt caatacagag
   132601 tggtactaca aacaaaatga cactgatggc tgtgactgca attagattga tccatgttcc
   132661 agctttcatc gtcagtccga cagaaaatcc gattgccgca aataaaacaa taacgacagt
   132721 ccaaactcca agattgctct ttttctcttt ttttccaatt ctaaatggtc gattcaactt
   132781 tgcatgtgta taacgcaatc tcaaaactgc gatccccatg atgacataga cgatacagta
   132841 gataacagta gttgaattta cgagcatcaa aaatgcttga ttgacgccag gaatcagcaa
   132901 ataaaaaagt gcaaagattg agataatgac agactgagtc aaaataacgg atttggatac
   132961 gtcaaattga ttcgtcttcc aaaaattgaa ttttggtgga tacgcacctt ttctagcact
   133021 ttctgtcact gtctttgctg gtcctgaggc ccaagcagat aattggactg ctacaccaat
   133081 gaagacaagt aaactaaaca gattcacaat aagatgtggc aaaccaagaa tttggcaata
   133141 aatcgaaata gattgcgcga tattattcaa ttccatttgt ccttttggta cgacatttgc
   133201 tacaactaaa gcattcaaaa tattgacgaa aaatataaaa attaacgcgg caaatactcc
   133261 gcgaatatac gttttaactg gattttccaa tcgagtgata tacacagagg acatttcgat
   133321 accagtaaaa ataaacatga tcggcgcaaa ataaacaaat gaggatgcag tcgtagtatc
   133381 tggtattaat ttgtcccatg aaaaactgcc taatgttccg gttggtacga tcccaacttt
   133441 gatccacgca gcaaacccta ataagagcat catcgtcaaa ggcacgtaca atcctaacca
   133501 aacaccgact tttccgccga tttttgccat atcaaatttc aaattcaaaa aagtgatgat
   133561 ccaataaacg actaaaatga caactaatgt aaatttgctg ttcaaaccaa gcggcacatt
   133621 atcgataata ttaccaaaca acggagcgag tgctgaagcg accatcacca tcccaggaaa
   133681 catttggacc cataacagcc atgagacaac gaacccccat ttttttccta gagcattcga
   133741 tacccaaagt tctggaccac ctttttgggg aaacattcca gcaaattcac cagagatcaa
   133801 tgagattgga aaagcgtaca ataatactgc aaccagcatg taaaaaatca tcgtccagct
   133861 cgttgctgct acatctggaa tatttcgtac acttgctaca agggcgcagg tcattccgat
   133921 aaaggtcatg gtcgtgattt gctttgatga accagtatct ttcatcttta ttccttcttt
   133981 caatagcgac atatgttttt gttttctttt atttttgttc aagaacagaa atgacaaggt
   134041 ttcatcgatt cagtacaaaa cccagtatca ccgaaacatc cattgaacga tcttagtgaa
   134101 ctgggtttga tacatgaaac gaacgatcca acttatagaa cgttttataa aaaagaatat
   134161 cttggcgagg aatatatgaa aaacaggggg aaatacaatt gttttgatga agcaaataat
   134221 tgtctgttct ccatatgtct cttgttattc tttcacacaa aaatcagttc tattggatga
   134281 tttcgtttag tttcttttcc attgctttgg cgattttttt tgtataaaaa ttgaaaattc
   134341 gatcatcatt caaataagga gtcatgatag ccgcacgtag cagagtgatt ttctgttctt
   134401 ttttccattc ttctttcgtt agacccattc tttcaacaaa acgaatcgga gaatcaccgt
   134461 aatcttcttg tgtaaatgta gtatgagaag taataaaccg ttcaccataa acatcgccat
   134521 ccatataaga agaccgatcg aacatttttt catttaattc attgatagcg ttcaaatctg
   134581 tacagccttg ttctttgaat acccaattga ccatattaaa atcaggatga ttcaatggat
   134641 agacttcgat tgtttttcct ttaacagtaa aagtcagatg atcgagaaat tctctgaatc
   134701 tttgagctgc ctcgattgaa gccccaatca attgaccata tccggtcaca ttcaatggca
   134761 atacacgatg tgctgtccag actgcggcgg cggttgctcc agcttttgat ccttccaaaa
   134821 tataagctcc taacatatct ggagccttta ctgatttttc aaacacatat ggcgcgaaat
   134881 aagaaatgat atttctcata tttttatgtt tgattacgat tcctccagca gcataaggga
   134941 catagcccat cttatgagga tctatcgtga cagaatccgc ttctgaaata gctctgaacc
   135001 cttcatatac ctctttgtca atcgttacgc agtggtggaa aacatgatgt tcttcaaaga
   135061 attcagctaa ggaagcatac ggcacaaatt ctcctgcttc gtttagaaac agtgaacgcg
   135121 catagccgcc atatgcggca tcaacatgta aatagaaata gatcccttca tcttttaacc
   135181 tttctcttaa ttggacgatt ttatctacac tgtctacttg accttcttct gtcgttccta
   135241 cgacagcaac cacacctaga attgggattt tttgtccagc taattcacga attgtttttt
   135301 ccaaagcatt aatatccatt cgataatcct cttgaactgg gatagcaacc atctgatcta
   135361 agccgactcc gcaaatatct aacgccttca tccaagaata gtgttttgtt tgagggacca
   135421 gccatttccc taatctttgg atattttttc cgctacggga agaagctgct ttgacctcat
   135481 ccatttcttc gtccgtaaag ctttcggtca tttccaaaat ttcttcaaca gataaattca
   135541 aaagttccca ctcagacatt tttttcactt tttcaggcag cacttccttg acagctaaag
   135601 gaatcgattt gatgcaacgg gcgtaccata atccttcaag attagcaata gaaccatctg
   135661 ctgcaatgtg tccccatccg tctgtcatat tgaataatga agcaaaatcc tgtcctactt
   135721 ctgcttccat ttgcgaagtt gccatagaag attccaatgc aacattattt gggttccaca
   135781 gcatcgcata gttgtaagct aataaagcag gcatcaatgt ttcagcattc atttgtcccc
   135841 agtaacggcc tgctgaatgc catgggatcg atcctgcgcg taatcgctga ctgacttcat
   135901 ccaagacctc tatcatatgg tcgcgggtgg ctagataatc tggagtgagc ttatctcctt
   135961 cgctaattgc aggcatatct gaaggaatat aattttctct ccatccaaga tgttcatcta
   136021 ccatcttgtt caacaacatt ttataaactg gtccattttc agctttgtcg cctataaaga
   136081 cggccttgat atccatatct ttcatttttc ttccctccat attttgttgg tcaatgtctt
   136141 gcagatacat gtgtttatct gtaacacctc ttcactatag cgccaaaaat gagaattttt
   136201 tttttataac atcaaatcca cgtagatttt tacaaacaaa aataaataaa gtcggatttt
   136261 tctgataatt caacgcaaaa aagcgaacaa tttttcaata aatcagtctt ctaaaataga
   136321 taacctaaaa aaagcgaaca aacaaataaa atgactgtcc ttcattcact aaacatattt
   136381 ttattttttt atattgttaa aaattcgcaa tttatttttt aatagaatta tctgttttcc
   136441 aaattttata acataaaaaa ccttttttaa cggcatttat atgctttttc agaaattaac
   136501 tgatgatttc aaaaagaaaa catgtcataa tatttcccat attgtgcaaa aaaatacaag
   136561 gcggaggctc tactatgatt gaagaatata ttgagaaaaa tattttaaga cagctgtttt
   136621 tatgtgggca attctatgta aataaagaag tcaatctaga aaagctctcc aatctcctgc
   136681 atgtttgcaa aaccacttta ctcaatgata tcaataacat aaaaaaagaa tttgaagaac
   136741 agatcgctta tacacatcgg gaaaaggacc gttacacttt atatttttca gaacatatac
   136801 ctcgatgcaa gatcatgcag caattgtctc aaaattcgtt gtttttaaaa acttgtctgc
   136861 tttatttgga agaagatgaa cctgattatc ttcaattaac tgaatgtgaa ttcatctctg
   136921 tcagcaaagc ttattcatta aaaaaacaag tattagctta ttttaatgac tgcgggatcg
   136981 aaatcgaccg ctactcccct cgattcactg aaatggaaag acgtctgctg cttcttaatg
   137041 tgtcgtatcg tttaggcggt tttaattctt gggagctacc tgaatcgttt tttgaacgtg
   137101 ccgatcgttt cattgaatcc gtaacggaaa atagtggcag attttatgat aaagaaaata
   137161 aagaaatctt atcgattggt tttgctatca gtttcctacg ccagcaagtg tgtgctgtga
   137221 caatagattc aaaatttatc gaagaaatca aaaaacgtcc tatttacaat tatgtcgaat
   137281 cagcatggga aaacactgat ttccaaacct attataaaaa agaagaattc gcctttattt
   137341 tgacactatt caatctttgt aattatggtt tccattctta tcagttgatt gcggaagact
   137401 ttcaacagct acaccaagtg tttattgaca atactcccga aataaaagaa ctagttgcta
   137461 cctttgaatc tcacttcaat caagaattat tcggaaacca accgttcgaa cgtgcgctga
   137521 ttcatctgat gcgttcggct tgggataact atcaattatt catgccagaa aaattttatc
   137581 ttttaaatga ggaacagaca aatttatata aagaagtcca gacaattttt tccagctggt
   137641 ccagccagtt accttatgat ctacggttga atcctaattg catgcgggct tttgtgatcg
   137701 aattgagcgg aattctccgt ctgacaaaag aacatctgac tatctatatc gtcacaaatt
   137761 cggatgttca ttatctgatt tatcgggaag ccttggaagc tgtaactact ttcgattttc
   137821 aagttgcacc aacaatttat tcaagtatat ctgatataaa gaagtatgcg cagcagtcct
   137881 caaaccgggt attatgtgaa cgtacattat atacaccaga tgcggtccaa tatgaaaata
   137941 ttattcctat ttcgatcaat acgatcgatc gagctatcat ttcagctgtg caaaacaaat
   138001 aaggggctgt gacaaaaatc atgtcacagc ctcttatttg ttgaagatgc ccatttctgt
   138061 aacaatctct tgatacacgt caggctcaca acctcactta ttttggacat ctacgggtcc
   138121 gatctcttta tttaaaaaat aagaaatgat ggttcggata actaccaacg ccgctagttg
   138181 gaaaatatcc tgcaaggtag gtttgataat cgattcgatg atcccagctg aaacaagaat
   138241 ttccaaactt agaagtatat agcctcccaa catcttttta atagcattgt tctcgctgac
   138301 tcggtcgctt tgcacttttg tatggacaaa taaatatttc aaaaaatcct tgattgatag
   138361 acaaacaccc caaaccaata aacagatagc aaagatatca agtcccagta caagtttttc
   138421 gaaatatgga agaagaaact gcatcaactc tgtcgtcatc ctacctctcc tcttctttgt
   138481 ttttctttgt cttctatttc ctgattcaag aaataagaaa tgactgttcg aatgataata
   138541 ataagtgcaa gcttcaaaat atctgtccaa gtcggcttga taactgactc gatgatatca
   138601 gcaacgacta gtacttccaa gcttaacaaa atataacttg ctagcagttt tcttgtatct
   138661 gcattacgag tattacgttc tgcatagttt ttcttgacat gagaccaatc aaaaagtttg
   138721 aatagaacaa gaacgatccc gacaattaag ataccgatag aacaaatatt taaaatagca
   138781 atgatccatt ctagaaattc aattaaattt gagcgaaaca tatacgctac ctactttctt
   138841 ttaatttgtt cctattcttt tattgtaaaa gaaagttacc ttgttcgtct atttaaaagt
   138901 tgttctaatg ataacggttc gcttaaattt ttctttttca ctctcccatt tttctccctc
   138961 catccataaa tcgtggaagt atccaaaaca acgtagcaag ttaaaataag gcttagtccg
   139021 tcatcagctt ttcaaagaag cactgtctcg gtgctttttt tgtacccaaa tttctaaaaa
   139081 tagaaccata cacctcctca aatcttttct tcttacctac cctattttta tttacaggaa
   139141 aatcagacac ttcttctttt ttgtcaaaat ttcctttttc ttctcgtcct atcatttggc
   139201 attctaataa aaacgaacta tccttggata tagaaagaga aaacaaggag gcgtttttca
   139261 tgagtaaaaa attaatcaaa gtcggcatcg gtttaggttt gcttgccctt ggcgctgcat
   139321 atctaggaaa aaagacagga ctattcgaag atgacagtca tttatatgat gaattcgaat
   139381 caatctagca tcctatttag ttgaatcact acggacatac ttggaagaca ttggaggaat
   139441 cacaatgaga aaaagtaaag caataatgat tggtgccggt attgccaata tggcagcggc
   139501 tgtttatttg attcaagaag gcaaatggaa aggggatcag atcacctttt attcattgga
   139561 tgatcacggt tcaaatgatg gtgcaccgac cgacactgta gtggatgaat attggaataa
   139621 aaaccatcca ttagaaaacc aaaaaggcta tattgctcga ggcggtcgca tgcttaatta
   139681 ccgtacctat gtagatttga tggatctgtt aagtcgaata ccttctgtta ctgagccagg
   139741 gatgactgct gaagaagata cgagagattt tgatgcaaaa caccgaacct ttgacaaagc
   139801 acgtttgatg gaaggtggca aaggaatcat tgatggcgga aaactgggat tcaataataa
   139861 agaccgtatt cttctgacta aactgattgc tatgcctgat tcagaagaag aaaaactaga
   139921 caatatcact atcgaagaat atttcaaaga tgatccacac ttttttgaaa caaacttctg
   139981 gtttatgtgg gaaacaacat ttgctttcag aacacgtagt tctgctcaag aattgcgtcg
   140041 ctatatgcat caaatgattt atgaattcac tcaaatcgaa catctagtgg gcgtcaatcg
   140101 aacacgttac aatcaatacg aaagtattat gcttcctttg atcgagtact tgaaagaaca
   140161 aggatgcaaa atcattttga accgccgtgt cactgactgg gaattcaaag aaacaccgat
   140221 gcaagatgaa atcactgtga ctggtttgaa aattaccaat acactgactc aagaagaaga
   140281 atacgttgtg gtcgatgaag atacagcagt tattttcact aatgggtcca ttacagattc
   140341 agctacttta ggagattacg aaacaccagc tgtagaaaat atggattatg gtgcagcttc
   140401 tagtctctgg aaaaaagcca gtgaacgttt ctacaacttg ggaaatcctg acaaattctt
   140461 tgctgatcga gatgcaagcg aatgggtcag ctttaccctg acgacgaaaa accatttgtt
   140521 gttgaatgaa atcacccgta tcacgactca agaaccagga aatgccttga attcatttat
   140581 ttcaaccaca ccgatcacgc cgttaggcca aaaagatgtc aatatgtcta tcgtcgtgca
   140641 tcatcaaccg cattttacgt ctcagaaacc aaatgaaaca gttatttggg gttatttcct
   140701 ttatccaaga cgacgtggcg aatttgtgga taaacagtat attaaaatga atggaaaaga
   140761 aatgctagaa gaactgattg gacaactttc aaaagtagat cctggaccag tgaatattcg
   140821 tgaaaaagaa acagaaattt tcgacagcgt aataaataat atccctgtct atatgcctta
   140881 tgcttccgcg ttgttcaata atcgtgccaa aagcgatcga ccaaaagtca ttcctaaaca
   140941 ttcgaccaat ctggccttta caggagaatt tgtcgagcag ccttatcaga tgatctttac
   141001 tgaacaaagt gctgtacgtt ctggagaaat cgctgctttc cattttgcgg gtattcctat
   141061 gtcccgtctt gtcaaaacac cgcgttacga caaagatatt cctactctag ctcgtgccgc
   141121 aaaaaaaatg tttgaataat caagaggttg tgaaaaagct gccctgcatc aagtaataag
   141181 aacaaccagg ctaaaacagc ttcttatgtt tttgatttgg ttggacttat taccgcagat
   141241 gcaagctttt gaacaccgtt taccaagagg ttgtgaaaaa gctgccctgc atcaagtaat
   141301 aagaacaccc aagctaaaac tgcttcttat gtttttgact tggttggact tattaccgca
   141361 gatgcaagct tttgaacacc atttaccaag aggttatgaa aaagctgccc tgcatcaagt
   141421 aataagagca gccaagctaa aacagcttct tatgtttttg acttggttag acttattacc
   141481 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaaggcg tttagtttcg
   141541 agtatgaaga aaaattttgt gaaaatggtt cctcacgttt ttgcataaat ttgacttaat
   141601 accgagaaac tgatcccttc tgtcataacc tctttttatt tatgtctgtt tctttttgaa
   141661 aacaactatt ttttcaacgt ttactctctt gccaatccaa catcatctaa cggatacaac
   141721 tatttcaatg attaccatta cactaaaaaa tcggaaacac acctctccga acacaaatac
   141781 ataagactat agaatgtttc atttaagaaa aaaagcgttt cattatcaaa aaggtaagat
   141841 ctcctttaaa atgaaattat ctgtagtact aataatgcag acaattttat gaatctgaaa
   141901 ggagcatctc caatgaaagc agtcacttgg caaggaaaac agaaaatgga aatcagaaac
   141961 gtagatgatc caaaaatatt agaaccaaca gatgcaatca tccgtatcac agcaacagcc
   142021 atttgcggct ccgatctgca tctttaccat catggtgaag cagttttgga aaaagggtat
   142081 gttgtaggac acgaaccaat gggaatcgtt gaagaagtgg gatctcaagt tcaaacattg
   142141 aaaaaagggc aacgtgtggt tatccctttt aatattagtt gtggtcattg tcatttctgc
   142201 ctgaatcaca tggaaagcca atgtgatgaa tcaaatccag atcagttata tggcgggctt
   142261 ttcggatttg gcaagttgaa cggtaatcat tggggtggtc aagcggaata tctaagagtt
   142321 ccttatgcag actctacttc atttgttgta ccagataatg atcttcctga tgaaaaagtt
   142381 ttatttctat cagatatttt gcccacagct tattggagcg ttgaaaacgc aggagtaaaa
   142441 aaaggcgata cagttgtgat tctaggttct ggtccagtcg gtctattcgc tcaaaaattc
   142501 gctgttatgg ctggagcaga gcgcgtaatc gcagtagatc cagtacagca ccgtctagat
   142561 aaagcggcta attacaatgg ggttgaaact tatttcttag aagacacggc acaagctgga
   142621 acagaattgt atgaactggc taaaggtggc gcagatgtca ttatcgattg tgtaggaatg
   142681 gacggattag agcctgtcaa agaaaaagcg aaaaatttag taagcttaca aagcggcaca
   142741 atctctccat tacagatggc atcgcaagct gtcaaaaaat ttggaacagt ccaagtaact
   142801 ggtgtttata tgactccagc ttcttcttac ccgctgcaag aattttttat gcgggatatc
   142861 gctgtcaagc atggacaggc accaattatc catctaatgc caaaaattta cgcaatgatt
   142921 gcagaaggac tattcgatcc tacacaaatc attactcatt cgctgccact atcagaagca
   142981 gcacaagcat atgagatctt tgacaaaaaa gaagataaaa atataaaagt tgttttgaaa
   143041 ccttgaattc agtaaaaaat acaggtgatt ttctttatgc ccaaaatcaa acgaaatacc
   143101 catgagatcg aaataggaaa agaagaagat atcgaaatac gaggacgtcg cttccgcttc
   143161 tatttccaaa atcgttacac attgatctca ctggctgtcg atttattaac cgggattttc
   143221 tatatttttg gaagccttgc ttccttaact aaaatccccg atcgatatgg cacctatttt
   143281 tatttggctg gtgctatttt cttgacgatt cgtcctattc tcagaatcgt aaggaacatt
   143341 tttatttacg acgaaaaaaa agcaatgaag agaacaagca aaaaaaaaga ggcatgagaa
   143401 tttttcaaat ctcatgcctc ttttttcacc ctatcgtatc actttgatac agacgagcgg
   143461 tcgtcccact ttcttccttg accattgtca aaaatgtcca ctcgtatcgt tcataaaacg
   143521 tggtatgatc tgtaattaag taaagttttt cgtacccaag ttgatgcatt tcttttctga
   143581 tttccgctaa tatccgcttg gctatcccct gcttacgctt ttccggttca acaaacaggg
   143641 cacaaagatt tggtgtcaga tcagggcggt tatggaagtc gttttcaatg acgcccgctc
   143701 ctccgacgat ggtttctttt tcatctaaga ccacatacca ttgaggaata ctttccttat
   143761 tagcgattcc agtacgaata ctttcctcat acacaacagc aggaactccc cattttgatg
   143821 aaaaccaatt cgcgctttgt tttactaatt ctgggtgttc tcttaatttg atccagttat
   143881 atgtaaccaa tgtttaaacc tccgactaaa ataaaacgtt tacaaaaatt atacaagtct
   143941 ttatgaaaat tagcaatgac aacaatagtg atgtaaaaaa aaaaacggaa aacaatcact
   144001 tgttctccgt tttttgattg atcaagcatc taaagcttct tttcttcttt cttggatcgt
   144061 agctaccttg acgaacggta gatagatcaa aatagaaaga accaaattga cagcggctag
   144121 tacaccacct gcaatacttt ttgttgccaa tacaccgcca ataattggtg gagttaccca
   144181 tggaggcata acggtagctg ctggcactaa acctgtagaa gtcgcaaagt aagcaacact
   144241 aactaagacc attggtgtca aaataaatgg aatgaacatg atcgggttca acacgatagg
   144301 taacccaaac atcgttggtt cattaatatt gaaggacacc tggcgcaatc gacaagtttg
   144361 ttacaaccat atatggtttg tttttacgtc ctactaaata aatagctaac agtaaaccta
   144421 aagttgcacc tgttcctcct aagttgacaa agctgtcaaa gaaaggtttg ttcacgataa
   144481 acggtgcgct atgcccagct gcgattgcat taacgtttgc ttcaatggct ggcgcattga
   144541 ttgtttgcat caaaggatcg accatattcg ctccgtgtaa accaaagaac cataagaatg
   144601 gtgtgataaa tgcaagcagt aaggcagatg gataagagtt tgcaagtccc ataaatggtt
   144661 cttggaccac tgtatagaaa gaacctacga tatcatcaac accgaatgca gcaaaaattg
   144721 cagcaactaa agcaaacgca gagatagtga tcattgctgg tagtaatgaa gcaaatgctt
   144781 ttgcaactgc cggtggcaca ccatcaggca ttttgatgat caatttttca tttccgctta
   144841 aacgtacaaa gatttctgtt gaaataatcc caacaataat agcaataaac aaaccgtttg
   144901 agctcatacc taatgctccg cctaaagcga agaaagagcc taaagaaatc acacctgcgg
   144961 aaacaccgtc ttttcggtag ccgttagcta aatgataagc aagcaagaaa gcaatcaaga
   145021 cagaaagaat ggcaaatgta ccgttccaag cagcagcccc gaatcctttc catgattcac
   145081 caccaaaaat tgagttcatc aattcttgga acccgggaat cggtaagtta ttgatcatta
   145141 ctgctaatgc tcctaagatc attaacggca tactcaccat aaatgagtcc cgaatcgcaa
   145201 ctaaatgccg ttgtgcacca atttttgatg ctacaggtat aaaatgtttc tccataaatg
   145261 caacaaattt atccataaat cttccctctt ttctttactg tagattacgc gttcaatcga
   145321 cgatacagat caatgatctc ttttgctaaa tctgtaaaag ctatagatgt catcagatga
   145381 tcttgactgt ggaccgtcaa aagcgtgact tcaacgtgat ttccttgtgc ttcttgtgtc
   145441 agcatctctg tttgagagtg atgtgcttgg actaaagatt cctctgcatc tttgattttt
   145501 tcatctgcta aagtgaaatc accttttttc gcagcagcaa tcgcttccat tgcatcgctt
   145561 tttgcatttc cgccaaacat gatcagaccc atgatggctt ctagattttt ttgatcttcc
   145621 atttattgta tcctccgata atttttatta tttgtttatt agtttttctg cttggtcgag
   145681 tactttttca ccattcatca tgccatagtc agccatattg attacatcta aaggaatgcc
   145741 tttaggtgct agcttttcag caaattgatt ttgcataaag cgtacttgcg gtcctaaaag
   145801 taaaacgtct acatttttag attctagttg attatccgca tctgaagcag atacagcaaa
   145861 gatgtctgct tccattcctt ttgcttctgc tgccttttgc atttttgtga ctaggagact
   145921 tgtactcatt ccagctgaac atacaagcat gattgttttc ttttccattt taaacacgtt
   145981 cctttctata cttacacttg tatataagca agtagcgtgc caactttaaa agcgctttaa
   146041 aaagttgata tcatcacatt taaggtctat accaagttgc atacacacta aaaaagaaag
   146101 cgcacactaa acacacaaat taatttttat tacctttttt cttttaacgt gcacaaaaaa
   146161 agttgtgaca caaaacttgt cacaactttt ttcaaataaa cggtattcaa aagcttgcat
   146221 ctgcggtaat aagtccaacc aagttaaaaa cataagatgt tgtttttact ttgctattct
   146281 tattacttga tgcaggacag ctttttcaca acctctcaat aaacggtgtt caatcagctg
   146341 accctgggta ttagctcaaa acgctggatt cacaacctct tttatttcaa ataaccagta
   146401 aatacaatga acatctacaa aaaacttcta tttatttata gatttcgtca ggcaaatcca
   146461 attctctctt atcaatcaaa gtctgatacc acgaagcaga ttttttcaat gttctgcttc
   146521 gttcatcgtt caattcgatt cgaactaatc catatcgatt cttaaatgca ttcattggtg
   146581 acacacagtc agtgaatgcc cataacatat agccttcgca atttgcgcct tcttctgttg
   146641 ctttgatcaa gtaatgcaaa tgctgtccga taaattcgat acggtaatca tcttgcacga
   146701 ttcctttctc atccatatac tgttcttcat attctcttcc cataccgttt tctgttatca
   146761 gccaagggat attatgataa ttttctttta gatacatggc tatatcatac atgattttcg
   146821 gatagatttc ccatcccctg gaattattca ttttcttccc aggtaaatca aagacttcat
   146881 aatatcgttc aggatggaaa ggtgtctctt cattccattg ataacgaggg gcgcgaacgc
   146941 gtttaggata atattgattg attccaagga aatctactgt atgatgctga atcgtttcta
   147001 aatcctctgt tgcaggatcg aaataaatcg attgtttttg acacaactcc aggaactctt
   147061 ctgtgtagta tccttttacc atcggatcaa aaaatactcg attataaaac aaatcataca
   147121 tataagcagc tttttggtct tctggagaat tggatcgagc atagaccatt tcaggattta
   147181 aaatacagcc aatccttcca ccataatttc cgctgcggta aatctctact gctttagccg
   147241 ttgctaaaac tttatgataa ttccacatca tccacttttt tgtgttttgt tcatgcggcc
   147301 agcgaacagc atccaaatag caacgcgttt ggggaacgat tggttcgttg aatgtaaacc
   147361 agttttttac cctatcaccg taacgatcaa aggcaatttg agcatactta gcataaaaat
   147421 caactacttt tcttgaagac cagccatcat atttttccaa aagaaaagct gggacttcat
   147481 aatgttccaa acaaatcatc ggttctacgt ctgcttcgat caaagagtcg atcatttcac
   147541 ttatatgctg agcatattct tcatctacta tacagttctc ataatcagta aaaaaacgag
   147601 cccaattgat agaagtccga taatgtgtca gatggatgga tttcatcaga tccacatcct
   147661 gctggtattg ttccataaaa ttagttgcta cggctgggcc atacccatta tgccaaacaa
   147721 aatgttcatt tttataccag ctatctataa acgaatcctg tccttctttt tttcctttcc
   147781 aaccttccgt ttgccaagca gaagatgcag caccaagaat aaaatttttt ggaatagtaa
   147841 ttttcatgat ttcctcctgt tttttagatc ccatcatttt ccacacgatt tgctactttt
   147901 acaaatggca gatagatcaa aatagaaaca ataatacaaa caagttgcgt aataactgca
   147961 ccgatatttc ctgctgttgc cagataagca ttgacgatcg gcggcattgg ccaagggacc
   148021 attacaactg ctttcgccgc aaatcctaaa gcggttgcaa aataaccaat cgttccagtg
   148081 ataagaggcg ttaagataaa cggaatagct aaaattggat tcagcatgat cggcatacca
   148141 aaaataactg gttcattgat gttgaagatc ccaggagcaa gggataactt ggtgatttgt
   148201 ttcatatctt cccgttttcc aactaacaat actgcaatca gtaaaccgat cgtgactcca
   148261 gacccgccca tactcatata catatcccaa aatggcatag taataatgtt cggtacttct
   148321 tttccagctt caaaagcttc cgtatttaca gcaattgccg ctaaaagcaa cggttcccgt
   148381 atcggcttca ccatttgatt tccatggata ccaatcaccc aaaagacttg cgcaataaac
   148441 atcaatagca aaatacccgg taacccttgt acgacacctt ctaatgggcg ttgtacgaca
   148501 ttgtaaatga tatcataaag gtacattcct gtaagttctt tgatgataaa tcccgcagcc
   148561 gcgatacccg atacagtcag aatcgtcggg aataaagcag aaaaactagc agaaacattc
   148621 gttggcacgg tatcaggcat tctcagctgt agtttcttct gtttcctcaa ccagcaataa
   148681 agttcaatag aaaggatgga gaccaacatt cccaaaaata accctttcgt atctgtatat
   148741 tgtttagcca atacgttttc tactataaca gtctgatttt cattcactaa ttcataaaca
   148801 gttggattaa cagataaata agacatcact gcgatgatac cagggaatac accatccact
   148861 ttattcagct tggctaattc gatccctatc agaaaaacag catagatggt caagaaactt
   148921 agtgtgacat agctgatggc agatgcgata ggctttaatt cttctaaaaa acgcaagaaa
   148981 cttatctgtg ctaagccatt ttccgagtca aagaccattg ctgaaaacaa tgtgccaaaa
   149041 gcacccgtaa taattaccgg aatcaatgca gcaaatgcgt tttttatcac catgatatac
   149101 cttaaattat tgattctcgt tgccacgttc cctaaaacat tggctaattt atccataaaa
   149161 ctcattccag atcccctcat tcctgcttct tctccttgac gtcatctctt tttgtctatt
   149221 agtcagcgct tacatttcga tgaacagaaa ctatttactc ctctttttta ccaaatataa
   149281 aacaaaaatt catctgatgt atttatcata aaatacatca gatgaactgt caattagttt
   149341 ctttttctcc tattattttc tgtaattctc tccgatttat tgccatatgg acagtcattg
   149401 catcaaacgc agcaagtgca ttccgccttt cgatggcctg aacgatctct gtatgaatat
   149461 cgatcgtctc gattttcaga tgctggatat cataattttt attaaacaaa gcaattgatt
   149521 cattaatgat tgggataata tgcagcaagg ctacgtttcc gctagcttct gcaatcatcg
   149581 tatgaaaatc gatgtctaat tgaacatgtt cttgtgtgcc ttctcgaaaa gaagtttcaa
   149641 tcttttgcgt taattttttc atttggacga tttgattctt cgttgcatat tccgctgcca
   149701 aacctgccat cttaggctcc aataaatatc tcagttcaaa taagtctcgt atcatccgat
   149761 cctgatcttc aatcaaagaa aaaccgagtg ggtcattggc aatccctcgc ttatcactga
   149821 caaatgtccc cgctccttgc cgaacttcaa ggatattcct ggaagctaga gcccgcacag
   149881 cttctcgcac cgtgcttcgc cccacctcta aataatcgga caattcatat tcattcggca
   149941 gtttatctcc tacttgcaac tgcatttcct ttaaatatct aaggatcttg tcagtagtta
   150001 cttctactag ggttttattt tcttccaaac cacatacctc cttttcatct gatgtatttt
   150061 ttcgtaatta ttataacacg tttgaatcat ctgatgattt tttgtataca aaattgatta
   150121 atccgttcat agacatacaa acgaagaaga tatttaccat aaaaaagact aggataaaat
   150181 tcactcctag ccttcgatca tttttatttt gaacgacaaa aaatatgatg ttcaataaca
   150241 gacgatcttc attcgattct tgatgtcatc ttttgttttt tttaatatat ggataaaaag
   150301 tttgattaca tcgtttctat tctagaattt ggtcgattct caattcttct tctggtgaga
   150361 aatctaaatt atccatcatt cgaacacttt cttgtaactg acttaaccga cttgctccga
   150421 ccagtacact tgtaacagat ttttgtcgca aattccatgc aagggccatt tgcgctaatg
   150481 attgtcctcg tgatacggcg attgtttgca gtgctttgat tttttccaga gttgatccaa
   150541 cttgttcttc tgaaaggaat ggtatttcct tacgatgtgc tctagaatct tcaggaatac
   150601 catgtagata acgatttgtc agcaaccctt gagcaagcgg actgaacgtg attgccccta
   150661 gcccttcttc ttctaatact ggagatagat cgtcttctag tagtgcacga gaaaacatat
   150721 tgtagcgcat ctgatgaata atgaacggtg cttcctttct ttttaaaatt tcagtcattt
   150781 tttttgtatc ttctccatta tagttggata taccaatata taatgctttt ccttgtctta
   150841 caagttgcat caaagcttct gctgtttctt ccaaaggtgt atcagggtct gggcgatgat
   150901 gatagaagat gtcaacataa tctagcccca ttctttggag actttggtca caacttgaaa
   150961 tgatggattt acgagagccc cattccccat atggcccttc ccacatatga taacctgctt
   151021 tgctagaaat aatcagttca tcacggtagg cttgaaaatc ttctctaaaa atacgcccaa
   151081 agtttttctc tgcagctcca gcagggcctc cataattatt cgcaaggtcg aaatgggtaa
   151141 ttcccatgtc gaatgcgcct cttaaaatct ctctttgatt atggatagga tcataatcac
   151201 caaaattttg ccataatccg agagataaaa tcggtaattt caaacctgaa tgaccggatt
   151261 tacgatattc cattttttca taacgtgcac tatctgcaat atacaatttt tctcctcctc
   151321 atcaaatctt tttaaaacgc tttctttttt ctatttttag tttactacat tttaaagaaa
   151381 aggagttaat caaaatgatt ttttcgtata tttttttgcc atttgttttt tactcgttga
   151441 tagatcagaa attgattacg tgcttgctgg atttttttat aacgtttcgg ttgttttttg
   151501 taaaattgct gatgatagtt ttctgctggc caaaacgtac cggctggttc gatttttgtg
   151561 acgattggtt ggtggaaagt tcctgaactg tctagtttct gttttgattg ttccgctaat
   151621 tctttttgtc gttcgccttg ataaaaaatc actggacgat attgcttccc tctatcttga
   151681 aattgtccaa atgtatctgt gggatcagta atttgccaat agattgtcag caactcgcta
   151741 taacttattt ctcttgtgtc ataaatgatc tccacagctt ccacatgacc tgtgtaacca
   151801 ccacttactt gatcataatt tggtttttca acatgtccgc ccgtgtatcc tgacaaaaca
   151861 gataggatcc cttttttcga ttcaaacggc tcgaccatac accagaaaca tccccctgca
   151921 aatactgcac gttcttgata gtcagcatct tgcatggcat gcttggaaaa gtcatatttt
   151981 tgctccttat caaatccttc cgtaatcaat aaataaaagt ccattacatc aggcgtcaga
   152041 ttcattcgga tagctaatgg acgtagtgtt gcttctagtt ttgataactg ttctttaacg
   152101 gatatatttt ctcttatgtc attctttgtc tgaatcaata cttttcgttc ccaatctcgt
   152161 gtattcggat tcaaaatcag attataaagt gtttgaatga atatttgttc ctcatccata
   152221 gattctcctc ctttccgaag aagacaagct agtgacttta gctgtaattt atcataaagt
   152281 gaggaaataa gcgattactt catcccccta cagatttttc gtataaaaaa gagagaatcc
   152341 ttatcgacag attctccttt ttaatcaatt tattttataa atgaaaagtt aatttacctt
   152401 ttatggaaaa ctattttaaa aaataaacat aaatatgcag ttaatgtaac aagataagaa
   152461 ataatagtcg ttactgtata acttgtgctt actttaatat cagcaactcc tttgactccg
   152521 cttatttgta ccaatccatt agcattcacc tgctccttta caggttgatg atttatttct
   152581 acattcgttc ctaaataagc atatacagga agtgtgatta cttggctctt ctcattagtt
   152641 actctatata tgatagaact accagttgtt ttataaggaa ggtttaccca ttgactgcca
   152701 atctttgctt cgtgttttat tatatgctcc ttattctcca atgaagcgat aggagaataa
   152761 tcatataaaa aataatccat tcctttagtg gtatacgcct ctactgtttc tttgtttaca
   152821 acaatatgtc ccggctgaga aattattttt tgattgaaat tttttttact agaaacagtt
   152881 aaagtgatta ataacaaaac agtcataaat aaataaaata gttctcttgt cttattgtat
   152941 cttctatttt tgaaaaatat catcgttaat atcagagaag agaatattat ttgcaagctt
   153001 aagatccgcc aaggaaattg taacaatttg gctggcgtat tttgcagaag ataccatggc
   153061 accaaactag ttgtagctag ccaagtcaaa cacgtaccat aataaatctt tttttctatg
   153121 tttgttaatt ttttaaataa aatcagggga atacataaag ataacagacc aactagtccc
   153181 attgagtaag tagttaagtc gttgttcata gcttcagtca gactatcgaa cacattagat
   153241 gcatgagcat ataaatttgt cacgctaggt ttgttgattt tttggtagag catttgttca
   153301 aacatcggat accaaaaagc actcgtcaga accaatgtca ttcctgccgc actaaataat
   153361 tttttaaata tagcaataaa atctgcattc ttgaaacctt tagaaaccaa acgaataaaa
   153421 atgataatta atgctgtact cattaatgtt gatagtacat ggctgtacac tagcaaactc
   153481 atactcaatg ctagctttac agacggatac ttttcttctt ttccagagat gatttgataa
   153541 gcataaaata atacagggat aacaagtgtt attgcgatag cttcggcaat tgcggaacga
   153601 tagtagatgt ctactgtccg ataagcagag aaaatataga gacaactaaa taaaaatgcc
   153661 gctttttttt gttttaaaaa ccgctcgcca taatgataag ctacgagtgt tgtacacaag
   153721 ttcaataacc aaacgtaaat aatatagctt acaatcaaat tttttgtcat ccaatataac
   153781 attacagctg gaaaaaaagt cagaaaggga taaaaataat ttacaccata tccagtataa
   153841 ttgaatgtct cataattaat cggactggta aaaatagtcg ataacccctt gattcgagat
   153901 aagtgaaaag aaagatctcc agtggtataa atactctgtg tatttttgaa aaagatgaaa
   153961 gaatatatac tactaactat aattaatcca ctcaatatta ctactttttt atttattttc
   154021 attcttcttg tttatctcct ttttagtcac atatcgagaa tctttcaact tattaggtgc
   154081 aaatcgttta aaacttgaat acaccactaa acaataagtc agaatactga tccataaagc
   154141 catgagagca gttggagtat attttgttgt aatttctatc ttattttctc cagcatttac
   154201 atccacattc actaagccat gttttttata agagtcattt acgactttac cgtttacttt
   154261 tacctgtgta cctaaataag catatactgg tactgtcact ttttgctttt tgttgcttgc
   154321 cactgtgtaa gtaatgttat tatctgcagc tttatacttc cctttttccc acgattctcc
   154381 tacttttact tcatgttttt ctaagtgagg cctttctttt atcgcttctg ttggggcgta
   154441 atcgtataat cctcccatat ctgatgttgt ataacgtggg agtgtttctt cattgataac
   154501 aatatgaccg tgttttgatt ggataacttt tgcgtaattt tcttttgctg ctatagacgt
   154561 gacgagtaga aacaccacag tagcgccaat gattaaccat gaatattttt tattcatagt
   154621 ctttttcata aaaacaagcg ttatgatcat tgaagaaaaa aagatttgga tacctaagat
   154681 acgccaagga aactggagca agcttatcgg tgttttttga aacaaaaacc atggaaataa
   154741 attagttacg catacccatg tagaaactac gccaacatag atgatttttt cttttttctc
   154801 catttctttc agtatgaata aaggaaaaat caacgcaacc aatcctaata accccatagt
   154861 gtatgttgta atatcgttat ttaacgcttg aatgatacta tctgaaatag aaagtgcttc
   154921 tagctgcaaa tctgttttga agggactgtg tatttcttga taattcatct gctgcaacat
   154981 aggataccaa aaatagctag ttaatgcaca agtcaaaaaa acagccttta ctaaattcac
   155041 gaccacaaat tttatatcgt tttttatttg cttgcttaaa aacaaacgaa ctataatcat
   155101 acaagcaatc aatgcactac acaatagtgt agttaagaca tgagtataca caagtagact
   155161 tatactgaca gataaagcga tgactttttt ttctctattg aatatcaatc cataagcata
   155221 atataaaaca gctgggataa tcgtaagagc gattgcttct gcaattgcgg atcgataata
   155281 gatatcaact gttcgataag ttgcaaaagt atataaacaa ctaaataaaa aagcagcatc
   155341 tatcttttta aaaaactttt ctccataata aaaac
//
LOCUS       DAFEIE010000002       118292 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFEIE010000002
VERSION     DAFEIE010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 118292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.002"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(30..731)
                     /locus_tag="LP345_000138"
     CDS             complement(30..731)
                     /locus_tag="LP345_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL1758957.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(747..1187)
                     /locus_tag="LP345_000139"
     CDS             complement(747..1187)
                     /locus_tag="LP345_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL1758958.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(1187..1762)
                     /locus_tag="LP345_000140"
     CDS             complement(1187..1762)
                     /locus_tag="LP345_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBL1758959.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(2610..3089)
                     /locus_tag="LP345_000141"
                     /pseudo
     CDS             complement(2610..3089)
                     /locus_tag="LP345_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(3248..3949)
                     /locus_tag="LP345_000142"
     CDS             complement(3248..3949)
                     /locus_tag="LP345_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1758960.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(4057..5466)
                     /locus_tag="LP345_000143"
     CDS             complement(4057..5466)
                     /locus_tag="LP345_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBL1758961.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(5514..7379)
                     /locus_tag="LP345_000144"
     CDS             complement(5514..7379)
                     /locus_tag="LP345_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1758962.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(7500..8351)
                     /locus_tag="LP345_000145"
     CDS             complement(7500..8351)
                     /locus_tag="LP345_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1758963.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(8661..9374)
                     /locus_tag="LP345_000146"
     CDS             complement(8661..9374)
                     /locus_tag="LP345_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL1758964.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(9442..9768)
                     /locus_tag="LP345_000147"
     CDS             complement(9442..9768)
                     /locus_tag="LP345_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL1758965.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(9891..10118)
                     /locus_tag="LP345_000148"
     CDS             complement(9891..10118)
                     /locus_tag="LP345_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL1758966.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(10440..11693)
                     /locus_tag="LP345_000149"
     CDS             complement(10440..11693)
                     /locus_tag="LP345_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL1758967.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            11754..12494
                     /locus_tag="LP345_000150"
     CDS             11754..12494
                     /locus_tag="LP345_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1758968.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(12580..13338)
                     /locus_tag="LP345_000151"
     CDS             complement(12580..13338)
                     /locus_tag="LP345_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL1758969.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(13335..14363)
                     /locus_tag="LP345_000152"
                     /pseudo
     CDS             complement(13335..14363)
                     /locus_tag="LP345_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(14383..17550)
                     /locus_tag="LP345_000153"
     CDS             complement(14383..17550)
                     /locus_tag="LP345_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758970.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSTDGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(17774..18658)
                     /locus_tag="LP345_000154"
     CDS             complement(17774..18658)
                     /locus_tag="LP345_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL1758971.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(18753..19190)
                     /locus_tag="LP345_000155"
     CDS             complement(18753..19190)
                     /locus_tag="LP345_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758972.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(19407..20318)
                     /locus_tag="LP345_000156"
     CDS             complement(19407..20318)
                     /locus_tag="LP345_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL1758973.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVENQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(20775..21203)
                     /locus_tag="LP345_000157"
     CDS             complement(20775..21203)
                     /locus_tag="LP345_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1758974.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     EKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(21231..21869)
                     /locus_tag="LP345_000158"
     CDS             complement(21231..21869)
                     /locus_tag="LP345_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1758975.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(21873..23855)
                     /locus_tag="LP345_000159"
     CDS             complement(21873..23855)
                     /locus_tag="LP345_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBL1758976.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            24035..24700
                     /locus_tag="LP345_000160"
     CDS             24035..24700
                     /locus_tag="LP345_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1758977.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(25769..27160)
                     /gene="sufB"
                     /locus_tag="LP345_000161"
     CDS             complement(25769..27160)
                     /gene="sufB"
                     /locus_tag="LP345_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBL1758978.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(27165..27635)
                     /locus_tag="LP345_000162"
     CDS             complement(27165..27635)
                     /locus_tag="LP345_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBL1758979.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(27622..28857)
                     /locus_tag="LP345_000163"
     CDS             complement(27622..28857)
                     /locus_tag="LP345_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL1758980.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(28854..30140)
                     /gene="sufD"
                     /locus_tag="LP345_000164"
     CDS             complement(28854..30140)
                     /gene="sufD"
                     /locus_tag="LP345_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBL1758981.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(30153..30926)
                     /gene="sufC"
                     /locus_tag="LP345_000165"
     CDS             complement(30153..30926)
                     /gene="sufC"
                     /locus_tag="LP345_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBL1758982.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(31123..31971)
                     /locus_tag="LP345_000166"
     CDS             complement(31123..31971)
                     /locus_tag="LP345_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL1758983.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(31995..32681)
                     /locus_tag="LP345_000167"
     CDS             complement(31995..32681)
                     /locus_tag="LP345_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1758984.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(32674..33708)
                     /locus_tag="LP345_000168"
     CDS             complement(32674..33708)
                     /locus_tag="LP345_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1758985.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(33771..34027)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(34103..34441)
                     /locus_tag="LP345_000169"
     CDS             complement(34103..34441)
                     /locus_tag="LP345_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBL1758986.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(34443..34799)
                     /locus_tag="LP345_000170"
     CDS             complement(34443..34799)
                     /locus_tag="LP345_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBL1758987.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(34805..35992)
                     /locus_tag="LP345_000171"
     CDS             complement(34805..35992)
                     /locus_tag="LP345_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1758988.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(36183..37028)
                     /locus_tag="LP345_000172"
     CDS             complement(36183..37028)
                     /locus_tag="LP345_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1758989.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            37262..38227
                     /locus_tag="LP345_000173"
     CDS             37262..38227
                     /locus_tag="LP345_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBL1758990.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            38604..39647
                     /locus_tag="LP345_000174"
     CDS             38604..39647
                     /locus_tag="LP345_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBL1758991.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(39709..40173)
                     /locus_tag="LP345_000175"
     CDS             complement(39709..40173)
                     /locus_tag="LP345_000175"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBL1758992.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            40419..41366
                     /locus_tag="LP345_000176"
     CDS             40419..41366
                     /locus_tag="LP345_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1758993.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(41577..43649)
                     /locus_tag="LP345_000177"
     CDS             complement(41577..43649)
                     /locus_tag="LP345_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1758994.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(43582..43959)
                     /locus_tag="LP345_000178"
     CDS             complement(43582..43959)
                     /locus_tag="LP345_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBL1758995.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(44088..44666)
                     /locus_tag="LP345_000179"
     CDS             complement(44088..44666)
                     /locus_tag="LP345_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1758996.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            44798..46090
                     /locus_tag="LP345_000180"
     CDS             44798..46090
                     /locus_tag="LP345_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL1758997.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(46150..47268)
                     /locus_tag="LP345_000181"
     CDS             complement(46150..47268)
                     /locus_tag="LP345_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBL1758998.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(47282..48703)
                     /gene="arcD"
                     /locus_tag="LP345_000182"
     CDS             complement(47282..48703)
                     /gene="arcD"
                     /locus_tag="LP345_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBL1758999.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(48949..50070)
                     /gene="mnmA"
                     /locus_tag="LP345_000183"
     CDS             complement(48949..50070)
                     /gene="mnmA"
                     /locus_tag="LP345_000183"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBL1759000.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            50474..51073
                     /locus_tag="LP345_000184"
     CDS             50474..51073
                     /locus_tag="LP345_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL1759001.1"
                     /translation="MNYFISDMHFFHEHLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(51211..52497)
                     /gene="efmA"
                     /locus_tag="LP345_000185"
     CDS             complement(51211..52497)
                     /gene="efmA"
                     /locus_tag="LP345_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBL1759002.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(52768..53112)
                     /locus_tag="LP345_000186"
     CDS             complement(52768..53112)
                     /locus_tag="LP345_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBL1759003.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(53249..54394)
                     /locus_tag="LP345_000187"
     CDS             complement(53249..54394)
                     /locus_tag="LP345_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL1759004.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(54574..55548)
                     /locus_tag="LP345_000188"
     CDS             complement(54574..55548)
                     /locus_tag="LP345_000188"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL1759005.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(55628..56503)
                     /locus_tag="LP345_000189"
     CDS             complement(55628..56503)
                     /locus_tag="LP345_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBL1759006.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            56633..58540
                     /locus_tag="LP345_000190"
     CDS             56633..58540
                     /locus_tag="LP345_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBL1759007.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(59081..62359)
                     /locus_tag="LP345_000191"
     CDS             complement(59081..62359)
                     /locus_tag="LP345_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBL1759008.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(62630..63175)
                     /locus_tag="LP345_000192"
     CDS             complement(62630..63175)
                     /locus_tag="LP345_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1759009.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(63187..63879)
                     /locus_tag="LP345_000193"
     CDS             complement(63187..63879)
                     /locus_tag="LP345_000193"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBL1759010.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(63898..64182)
                     /locus_tag="LP345_000194"
     CDS             complement(63898..64182)
                     /locus_tag="LP345_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759011.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(64195..64758)
                     /locus_tag="LP345_000195"
     CDS             complement(64195..64758)
                     /locus_tag="LP345_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL1759012.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            64986..65648
                     /locus_tag="LP345_000196"
     CDS             64986..65648
                     /locus_tag="LP345_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBL1759013.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            65772..66968
                     /locus_tag="LP345_000197"
     CDS             65772..66968
                     /locus_tag="LP345_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBL1759014.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(67069..68445)
                     /locus_tag="LP345_000198"
     CDS             complement(67069..68445)
                     /locus_tag="LP345_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1759015.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(68482..69348)
                     /locus_tag="LP345_000199"
     CDS             complement(68482..69348)
                     /locus_tag="LP345_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBL1759016.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(69437..70462)
                     /locus_tag="LP345_000200"
     CDS             complement(69437..70462)
                     /locus_tag="LP345_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1759017.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(70480..71154)
                     /locus_tag="LP345_000201"
     CDS             complement(70480..71154)
                     /locus_tag="LP345_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1759018.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(71338..72231)
                     /locus_tag="LP345_000202"
     CDS             complement(71338..72231)
                     /locus_tag="LP345_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1759019.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(72305..74002)
                     /locus_tag="LP345_000203"
     CDS             complement(72305..74002)
                     /locus_tag="LP345_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1759020.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(73995..75308)
                     /locus_tag="LP345_000204"
     CDS             complement(73995..75308)
                     /locus_tag="LP345_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL1759021.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(75308..78826)
                     /locus_tag="LP345_000205"
     CDS             complement(75308..78826)
                     /locus_tag="LP345_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL1759022.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(79119..79577)
                     /locus_tag="LP345_000206"
     CDS             complement(79119..79577)
                     /locus_tag="LP345_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1759023.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(79875..80393)
                     /locus_tag="LP345_000207"
     CDS             complement(79875..80393)
                     /locus_tag="LP345_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL1759024.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(80395..81012)
                     /locus_tag="LP345_000208"
     CDS             complement(80395..81012)
                     /locus_tag="LP345_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL1759025.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSFYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(81009..81863)
                     /locus_tag="LP345_000209"
     CDS             complement(81009..81863)
                     /locus_tag="LP345_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1759026.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(81860..82771)
                     /locus_tag="LP345_000210"
     CDS             complement(81860..82771)
                     /locus_tag="LP345_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1759027.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(82812..84146)
                     /locus_tag="LP345_000211"
     CDS             complement(82812..84146)
                     /locus_tag="LP345_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1759028.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            84354..85184
                     /locus_tag="LP345_000212"
     CDS             84354..85184
                     /locus_tag="LP345_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBL1759029.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(85428..85746)
                     /locus_tag="LP345_000213"
                     /pseudo
     CDS             complement(85428..85746)
                     /locus_tag="LP345_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(85868..86062)
                     /locus_tag="LP345_000214"
     CDS             complement(85868..86062)
                     /locus_tag="LP345_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759030.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(86567..86752)
                     /locus_tag="LP345_000215"
     CDS             complement(86567..86752)
                     /locus_tag="LP345_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759031.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(87602..87943)
                     /locus_tag="LP345_000216"
     CDS             complement(87602..87943)
                     /locus_tag="LP345_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1759032.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(87943..88173)
                     /locus_tag="LP345_000217"
     CDS             complement(87943..88173)
                     /locus_tag="LP345_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1759033.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            88460..88798
                     /locus_tag="LP345_000218"
     CDS             88460..88798
                     /locus_tag="LP345_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759034.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(89003..89242)
                     /locus_tag="LP345_000219"
     CDS             complement(89003..89242)
                     /locus_tag="LP345_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL1759035.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(89218..89565)
                     /locus_tag="LP345_000220"
     CDS             complement(89218..89565)
                     /locus_tag="LP345_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL1759036.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(90297..90878)
                     /locus_tag="LP345_000221"
     CDS             complement(90297..90878)
                     /locus_tag="LP345_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1759037.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLVKERLLTSQKVL"
     gene            complement(91061..91687)
                     /locus_tag="LP345_000222"
     CDS             complement(91061..91687)
                     /locus_tag="LP345_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1759038.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(91709..93040)
                     /locus_tag="LP345_000223"
     CDS             complement(91709..93040)
                     /locus_tag="LP345_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBL1759039.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(93195..93596)
                     /locus_tag="LP345_000224"
     CDS             complement(93195..93596)
                     /locus_tag="LP345_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL1759040.1"
                     /translation="MKKAYETAMINHGGRNGEVEEPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVFEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(93682..93888)
                     /locus_tag="LP345_000225"
     CDS             complement(93682..93888)
                     /locus_tag="LP345_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759041.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(93983..95485)
                     /locus_tag="LP345_000226"
     CDS             complement(93983..95485)
                     /locus_tag="LP345_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBL1759042.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(95503..95958)
                     /gene="argR"
                     /locus_tag="LP345_000227"
     CDS             complement(95503..95958)
                     /gene="argR"
                     /locus_tag="LP345_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL1759043.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(96056..96673)
                     /locus_tag="LP345_000228"
     CDS             complement(96056..96673)
                     /locus_tag="LP345_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBL1759044.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            96894..98267
                     /locus_tag="LP345_000229"
     CDS             96894..98267
                     /locus_tag="LP345_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1759045.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            98342..99454
                     /locus_tag="LP345_000230"
     CDS             98342..99454
                     /locus_tag="LP345_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBL1759046.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(99526..101163)
                     /locus_tag="LP345_000231"
     CDS             complement(99526..101163)
                     /locus_tag="LP345_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBL1759047.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(101331..101939)
                     /locus_tag="LP345_000232"
     CDS             complement(101331..101939)
                     /locus_tag="LP345_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1759048.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(102324..103475)
                     /gene="queG"
                     /locus_tag="LP345_000233"
     CDS             complement(102324..103475)
                     /gene="queG"
                     /locus_tag="LP345_000233"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBL1759049.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(103494..104246)
                     /locus_tag="LP345_000234"
     CDS             complement(103494..104246)
                     /locus_tag="LP345_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759050.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKNADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(104387..105337)
                     /locus_tag="LP345_000235"
     CDS             complement(104387..105337)
                     /locus_tag="LP345_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL1759051.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(105338..106177)
                     /locus_tag="LP345_000236"
     CDS             complement(105338..106177)
                     /locus_tag="LP345_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL1759052.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(106174..106920)
                     /locus_tag="LP345_000237"
     CDS             complement(106174..106920)
                     /locus_tag="LP345_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL1759053.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            107158..108528
                     /locus_tag="LP345_000238"
     CDS             107158..108528
                     /locus_tag="LP345_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1759054.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(108583..109479)
                     /locus_tag="LP345_000239"
     CDS             complement(108583..109479)
                     /locus_tag="LP345_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1759055.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(109593..109763)
                     /locus_tag="LP345_000240"
     CDS             complement(109593..109763)
                     /locus_tag="LP345_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759056.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(109760..110437)
                     /locus_tag="LP345_000241"
     CDS             complement(109760..110437)
                     /locus_tag="LP345_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL1759057.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(110528..111433)
                     /locus_tag="LP345_000242"
     CDS             complement(110528..111433)
                     /locus_tag="LP345_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL1759058.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     KNFKNIALDTLKKQLEKQTTVSWTT"
     gene            111608..113062
                     /locus_tag="LP345_000243"
     CDS             111608..113062
                     /locus_tag="LP345_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1759059.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            113078..114109
                     /locus_tag="LP345_000244"
     CDS             113078..114109
                     /locus_tag="LP345_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL1759060.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            114116..115303
                     /locus_tag="LP345_000245"
     CDS             114116..115303
                     /locus_tag="LP345_000245"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBL1759061.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            115459..116841
                     /locus_tag="LP345_000246"
     CDS             115459..116841
                     /locus_tag="LP345_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL1759062.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            116813..117199
                     /locus_tag="LP345_000247"
     CDS             116813..117199
                     /locus_tag="LP345_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759063.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(117399..118067)
                     /locus_tag="LP345_000248"
     CDS             complement(117399..118067)
                     /locus_tag="LP345_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBL1759064.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        33711 a        24836 c        20840 g        38905 t
ORIGIN      
        1 tttctttccc gtcgtttggt tttttatttt tagcctaatt cttgaccttt tgcatgctgg
       61 ttatccgtaa aatattttcc agcaggcttt ccttccaatt cagctaattt ttcttggatc
      121 tgacggatca ccttttttgc atcttctgga ttttctacaa aatcgaattt atccccatcc
      181 acttgtattt taggacatac atcaaaatct tcataccatt gattatagcg ggtgttcaac
      241 gtttcataat aggtatataa cgtctcatcg ctttctagct gttcatagtc acgcccacgt
      301 tttttgatac gttctagcat cgtgtccaaa gaaactttga tatggaccat caaatcaggc
      361 cgtttttttg gagcaacatc atctaactcg tttagcatcg tatctaataa gctatcgtac
      421 tgctgtactt cgatatccgt tacccgacct aaatcagcgt ttagatggaa caacaggcta
      481 tcttcataga tggatcggtc tagcacattg tcatcgttca ctaaagcatt tttcattgct
      541 aaaaatcgct tgttcaaaaa gaagatttgc aataaaaaag cgtactgctc aggatttgaa
      601 taaaagagcg gcaatacttc gttatcttcg acattttcat aaaatggttt agaatcaatc
      661 tcttttgcaa gcatatccgt caaactgctc ttacctgcac caatcgttcc tgaaatcaaa
      721 atcactgaca tacaaccctt cctcttctat aagtactcgc ctacgtaagt ttcaacaggc
      781 aatgtttcaa aatcatattc acgtacagct tggtctgatt ttaaatacgt atggagactt
      841 tgtgtaatca tcaagttcgt aggtaccgtc tcttcttgta caatgatcat cggttttttc
      901 aacatagttg ccacacctaa ttcgtaagcc gttcctggat cgattgtttg atgctcaaag
      961 tcaaggatag caacaacaaa ttctgcattt gtcagttctt ccatatcttt ttcgtatact
     1021 tcctgcgccc atccagcgct gaatagttca taattgcttt cttggtgatg acgtggagag
     1081 tagaaacttg tgactgtttt gttttcctcc aacgcttttt cgatacgact tactcgatcg
     1141 atttgctcct ctgaaaaaaa tggtcctgct aaatatattt gactcattat tttgcctcct
     1201 tcaataataa ctgattttta atagatactg ctcgtaattc attgaccagt tccaatggat
     1261 tgttggaaaa gattacttga tccaaccatt ttttatccat aaaatcctct tttgcaaaag
     1321 tttctaataa ttgttgcaag ccgctgtaat aaccgccaat attcaatatt ccgattggct
     1381 tgtcgggcgt cagaccgatt gctatccaag aaagaagttg tgagaattcc tccaatgtac
     1441 ctagacctcc agggaaaacg aggacagcat ctcccttttc aaataataat acctttcttt
     1501 catcgatcgt ttctgtagga ataaatgtag taacatcttt tccaggcaat tcagtttcaa
     1561 aaagcccatt cggatagata cctgtgactt ttccgttatt ttccagtact gttttactaa
     1621 tcactcccat aatcccggag tatgaaccac cgtaaaccag ttcgatttct tcttgtgcca
     1681 tgtattttcc taacgtttgc gcaataaatt tgtaactttc tttattacca aaacgggaac
     1741 cgcaaaaaac agtaagtttc ataaaaaaac actccctaac tcaaaagtct atcttcattc
     1801 tacacgtgtt tttttaaaat aaaagactag attttgtagt tttttagtgg tatataggat
     1861 agacgccact atatatagta tttagaaaaa aatcattttt cagccatttt atagataaaa
     1921 caaaaataaa taacgtgttt tcatcgatat gaaatgactt acttatagaa gatactggga
     1981 tttcgtccta tatgccaata acgtgtatta ttttaaacaa caaatacttg tttcttttat
     2041 taacgaaaaa atcattttgt tctcgtgtta tgtttcactg ataaatgatg tttctctaaa
     2101 taaaaaagcc gacgaactaa acgatcaaaa tttgatcatt tttgttcatc agcttctcct
     2161 aaaaatcttt ttgttaacga taaatagctg gatttgtaaa aatatcactt gaatcgtcac
     2221 tgctggaaga aaattcagtg ataaccgcac ctgttgcgcc tgcctggaac tagtgtttga
     2281 tattgggctc gaacgtgtac tgatctctag catgaagaat aatttctttt tttactgtat
     2341 aataactttc tttccttttt ggaatagtac aggaaagttt ttttgtttcc tttccttcga
     2401 cataaggtat accagaccct ttcgacaacg aaaggttctc atttttcctt catcgtcatt
     2461 tcaaggaggg tgccgatgct ctggacagtt tcgatcgctc ctaaaccaaa atctgtatat
     2521 tcgattcttt ctaactctga ttctttcata ccattcctgt ctcaaggtac atctattgta
     2581 cttttttctt gtaatccatt ctgcctctcc taactaattg tcaaatcatc ccaagatatg
     2641 tcttcttcct ctttttcttc ttggatgatt tctgcattcg gatctactgg ttttttcaat
     2701 aataaaatgg ttattcctgt gacaaaagaa ccagctaaca atgcaccaat gaatgcccat
     2761 ggtctggtca tcgtagcgac tgcaaacatt cccgatgccg gaatacggct atctgcgccc
     2821 caaaacatgc ttaatccgcc acctactgtc ccaccgactc ccgttgctat gacattgcgt
     2881 gccaagtcgt tcaatacgat agggaaacat ccctctgtga tctgacagat ccccatagga
     2941 aaagcggtct tcaatgtatc gatttcttga cgattgagta tatttttacg aatgattttc
     3001 cctaagaaat aagcgatcgt caagccgaat ggggttacca tcgaagctaa aatcaataca
     3061 gtgattggtt catagattcc ttctgaaaat cgtgccacac ccccttatcc agaataaatg
     3121 gtaatccaga aacagccgtg tatctgcggt aataagccta accaaacgaa aaatatgaga
     3181 agctattttt gtttggctgt tcttattact tgatgcaggg cagctttttc acaacctctt
     3241 tttttattta tgtttcataa tcaatatggt aaggatgcag ctccgtatgg tagaccgcct
     3301 ccgaatattc aatcatttcc ccaatttgcg tagacgattt ccgtatccgt ttgatgccga
     3361 tctgtgcgtc tgttttcaga attccttgtt cttcttctgt taaaaatact gccgagaaat
     3421 catcagaaaa tgagtcaata gtatatcctt ttttcgtcag caaacgatac aaagattctt
     3481 tgccaaattc ttctctgctg aattgcatca tttcttgtgg aagataatga acaaaataaa
     3541 tataaggctg attgttcaaa taatataagc gcttaaaaca aacagcttgc tcaccgaaaa
     3601 aggaaaacaa aggatcttcc ttctttatat ggaccaattg caaatccagc gtttctttcc
     3661 ggacttcata tcgggagttc tccaagattt gcgtaaagct tgccgctttg gataatcgat
     3721 tgtaaggacg attgcttaga accgtcgtcc cacgaccact tttctttgcg acatattcat
     3781 ctgatgccag cagttcgatt gcctttcgga cagtgatttt gctgacttga aacagttctt
     3841 ctaattcact ttctgtcggc aacatcgaac cgactggata ttttcctgag aaaatatctt
     3901 ctttaatttt atctgcgact tccaagtata gtacacgtgt ccttttcata acgtcaccct
     3961 ttgctttact attactaaaa gaatagcaca taaaaaataa aaaaagaaca caaatcacat
     4021 gtgagaagtg tgttcttttt cattcagctg ctttaattac aagtttacgc catttgaggc
     4081 aattacttct ttataccaat caaaagattt tttctttgat cgattcagtg tcccatttcc
     4141 ttcatcgtct agatccacat agataaagcc gtaacgttta ctcatttctc ctgttgatgc
     4201 actgacaaga tcgatacatc cccaaggcgt atagcccatc aaatctacac cgtctgctac
     4261 tgcattagcc atcgcttcga tatgacgacg taaataatcg atccgataat catcaataat
     4321 cgtgccatcc tcttccatat gatcaatggc tccaagaccg ttttcaacaa tgaataatgg
     4381 tttctggtaa cgattgtata attcattcaa tgcgattctc agcccttctg gatcgatctg
     4441 ccagccccat tcacttgcct caagaaacgg attttttact cctcccagca agttcccttc
     4501 tgaagttgct gcttgtggat cagtctcatt gattgccgta gacatataat aactaaatcc
     4561 gatgtagtcc actggatatt cttttagcaa ctggaagtct ttttccgttt gctctaattt
     4621 ttccggatcg actccatatt ttttatgggt acgcgctgtg tatgcagggt attctccacg
     4681 tacttggaca tccgtgcaga aaaaattgaa ttcttggttt tggatcattg ttgctgcctg
     4741 attgactgga ttggcatcga tgctgtaagt tgttgcatag ataatcatgc agccgatttg
     4801 gatatccgaa cgcaattcgt ggccgatttt tacggctttg ctacttgcaa cgaattgatt
     4861 atgccatgct tggaaaatat tttggtactc tcctgctcca ttgcttttta ctaatccttg
     4921 acttaaagct ggaaagtgaa aggccgaatt gatttcattg aaagtcatcc aatatttgac
     4981 tttactgctg tatctctcta atactgtctg agcaaatcgt tcatagaagt cgatcagttt
     5041 tcgatttttc cagccaccgt attcttttgc caaatgaaga ggcatttcgt aatgagaaat
     5101 cgtgatcaca ggttcaatat catattttaa gcactcatca atcagctgat cataaaattc
     5161 taatcccgct tcgttaggag taccttcgtc tccatttgga aaaattcgtg tccaggcaat
     5221 cgaaaaacga taacatttga atcccatttc cgcaaacaag gcaagatctt ctttgaaacg
     5281 atcgtaatga tcgattcctc gatgattcgg gtaaatatat ttttcttgat caatcgtcca
     5341 gtcaaattct tcactgccga taatcgcaaa gcgctgctta cctccaggca tagcatctgc
     5401 aacggatagt ccttttccgt ctcgatcata agccccttct aattgatttg gcagcagttg
     5461 ctccacccca taaaaatttt tctgaaaaac gtgattgcat cctgatttcc tccttatttt
     5521 acaattgcca gaacatcttc gtttgcaata atctcttttt ggtctaattc aagtatatcg
     5581 gcaaatgcat cagtattcgt aatgacaact ggagtgatta cgctatagcc agctgctcta
     5641 attgcttcga tgtcaaaacg aatcaataaa tctcctgctt tgacgagatc cccttgtttg
     5701 actaagatct caaagccatt cccatttaat tctactgtat ccatcccgat atgaatcaaa
     5761 atctccgctc cgtcagtcgt tgtgatccct acagcatgtc cagttggaaa aatagtcgtg
     5821 atctctccgt ctgcaggtgc aactagttct cctacttctg gatcaatagc gatacctttt
     5881 cccatcacgc cagaagaaaa aacttggtct ggtacttcac tcaatggcag tactttaccc
     5941 gttaaaggac tttttaaggt atgccgtgct gaagtaatcg gttctcctgc attcgcatgt
     6001 ttgttttcta attgattgtc ttgtgtttgt tcgtcaaatc ctaaaatcaa tgtacctacg
     6061 aatgcaagaa caaaagcaat tcctgtagct attactgcta ctgtcacatt tgactctaca
     6121 ccatccaccg tattaatgaa agtcggaatc gtcaataagc tgaccaaact gctggagaaa
     6181 gcttttactc cggaaaatcc gataatagct ccaccaatac ctccagaaat acaagcggca
     6241 atgaatggtt tcttcaaagg taatgtcaca ccatacacag ttggttcagt gattccaaat
     6301 aacgaagtca ctgtagaaga aatccctaat gctcgaagtt tcgtatcttt tgttcgcaat
     6361 gctacagcta aagcagcccc accttgtgcc aagatggctg gaagaagcat tggcatcaat
     6421 acatcaaacc catattgttc gatattcaaa aacatgatcg gtacgaatcc ccaatgcatg
     6481 ccgaacatca cgaatacttg ccataaactt cccatgatta gacctgctac gattggacta
     6541 aatccataaa tcgagttgaa gagaccgcct aaagcattac cggcaaccgt cccgattggt
     6601 cctaaagcaa gaaatgttaa tggaaccatc actactaaaa cgacaagcgg aactaaaatc
     6661 atttgcagaa attgcggaat cacttttttt acgaatggct ctaatttact ttgaacccat
     6721 acggctagaa tgattggtat gacagaagaa gtataaccag atggtgaaag aatcactggg
     6781 atcccaaaga aactgatagc ttctcccgca ccagcaactg ctgtgatagc tggatacaca
     6841 agtgccatag caattgctac tgctaaaaac tggttggctt tgaacttttt agctgctgta
     6901 aaagcaagca tgacaggtaa gaaggtaaag acaccatctg ctgcagcaaa caatatttga
     6961 taagtaccgc tatcagctgt cagccagccc atcaccgttg ccaatgataa gaatcctttc
     7021 aataccccgg cggctgccat cgcccctaga aaaggtgtaa atatactaga gataatatcg
     7081 atcagacgat tcaaaatatt tttggactct tcttttccat cctccgaaac tgcaagacct
     7141 tcctcatcca cgatcgattg ataaacatct gctacattac tgccaatcac tacttgatac
     7201 tgaccgccac tttgtacgac ttggatcacg tccgggtctt cttttaactt ttgcgtatct
     7261 gctaaagatt catcttttaa tctgaatcgc aaccgcgtag cacaatgtac taaacttttg
     7321 acattctttt gtcctcctac cgcttcccat acacgacgac caactgcttg attatccatt
     7381 gttttttcct tctttctttt ttatttaaaa aataaaaacc cagattgaaa aaaacagtca
     7441 caaacattcg tgaacctatt ttttcaatcc aggttttgcc tgccatacag taacaatcct
     7501 tatgattgga tgcttttttt ctcacttact actctttgaa tatgaatcgt taaataaatc
     7561 tgctctgcga tccccatttc ctgtttttgc gtttgtcgaa gatactcatt gatccgttcg
     7621 acacaatgaa acgcttttgg atactttcct tgaactaatg cgtagagaaa ttcatcttgc
     7681 tcgtcagatc cttccccttt gagataacgc tgggcaaaaa actgcagatg agtaatgata
     7741 cgctgataat tcaaagattc ttcatcgaac acgatgccga agaatttact gatgatactc
     7801 agtatatctc ttaccattgt ggtagcggtc atcgtcactt gcatgtcttc gtttccttgt
     7861 tggctattca caaaatgaaa ggcaataaaa ccggcttcat cctcagaaag ttccacaccc
     7921 gtcttttgtt tcacgaacaa aagagcctct ttcgctgctt gatattcttt cggataaaat
     7981 ttttttgttt caaataataa tggattaggc agttggatat tttcttttgc tcgtgtgatc
     8041 gcataatgaa gatgatcggt caatgtcaga taaatattag gcgaaaattc aacttttagt
     8101 ttatcttcag ccagttcgac tacttgtttg acccattcga tctcctctgc cggaatatca
     8161 gccatcagct gctggaattg gtttttagca aaagaatctc ttaaaacaaa ttctttttgg
     8221 accgcttctg gcgaaatctc gtccccaatc tttttttgaa aagctagtcc ttttcccata
     8281 caaacgactt cttccccgaa tccatttttc gaaatgacga cattgttatt caaaatttta
     8341 tcaattttca ttttgcttcg ccctctcaag aaaaataaaa aaacctagaa ttcgcctact
     8401 gtttcttagc tgaattctgg ttttgcctgc cgtacagtaa caatccattt cttattcaaa
     8461 atcatcatac catcgaattt ttatttatgc aagccttttc atataaaaaa taaaaaaact
     8521 ggaacacaag tctatctaga aaacaaccaa atcagagatg cacctctttg cgtttctctt
     8581 tttttcagca aattggtttt tccttatcga ttcatatcct ttggctgttt ttaatctgta
     8641 acgacttatg tcccagtatc ctaaaatgtt tttgtctcta gattgaaagc agatctcata
     8701 tcatctgtcg catcttttat cgatgtaaca ctttccagtt ctccttgtac aactagtcgc
     8761 gtgacggcgt ccatgtcgcc acaagtaatt agtgtgacaa tttcttttcc ctcgacttca
     8821 ttcagtaatt gggtatctgt aggagcaact ttttctttaa aaaatgtttt gtatgtatac
     8881 acattttcta aatctgtcaa atagatcttg gcacccatct ctaaattttc tagcggtgta
     8941 aacagcaatt cagggttcgt tgcacgatgg cttgctaagg cataatttcc ttttcccatt
     9001 tcttgatctg gagataatgt tcctgctccg taaagtagtg acgtattatc caagcctttg
     9061 aaaaccggta aattgattga aactgaaggg actgcgatac tagcaatcac tggtagatct
     9121 gttcctctca tttgcgacct catgacccct tctgtcgtca ttggttctac cgcatcaaag
     9181 tcaaaactga catctttatc gttattcttt ttcagatctt cttttgttac attcgctata
     9241 gcatatttat ctcctgtctc tctgacaaaa taatccttga tctgttcatt gaaaatcaaa
     9301 gctagtccta ctaataacaa gaggaacaag aggatattga ctagccatct ttttgctttt
     9361 cctttttttt tcattttctc tccctccaga ctcattttac tgtttttctt ttgctctttc
     9421 caacagccga atgacacatt tctacaactc tgtgtatttt tttcgtacac ctgcgctttt
     9481 ttctacagga tatttcaaat tatttttgat caatttttct tcaatgatct catctagatc
     9541 caggtgaagg ttgtctgcca tcatgtatga atagatcaat acatctgcca gttcttcttt
     9601 gattcgttct aattgtgttt cttttacttc ttccggcgtt ttccattgaa aaagttctaa
     9661 caattcagat gcttccaaag aaatagagat agccaaatct ttttcgttat gaaattgtcg
     9721 ccaattacgt tcatctctaa actggttgac tttttccata ctattcattt gcttgccttc
     9781 ttccaatcac ttcttacttg attaatcata ccattttttt acataaaaaa tagatgatgc
     9841 ttttaaaaaa actcctgttt tcttttattt aaaataaatg tcatagaaaa tcaataattt
     9901 aggtagccac catgtgtatg cagtagcgtg tcttcttccc ttgaggcttt ttgtttttcg
     9961 atacgttctt cttcccaaac agacaacgct actagaatct ctcttaatga ttttccttct
    10021 tcggtgagcg agtactctac tttaggcggg acttggttat aggcttttcg atggatactt
    10081 tcatcttgtt ctaactctct taactgctgg gtcagcattt tttttgtgat cgtagggatt
    10141 tgcttgcttc tccacgccta aaataagcga tattgctctt ccctttatct ggtgtaagca
    10201 aagcagttag cattttgacg atcgtgggtt ccgcttttca cttcttatct acttagtatc
    10261 atgaagtata ctttcgtact aatactaagt agcggaagtg tcaactactt tgtttaacta
    10321 catagcaaaa gaaacagaag ggtgacaacg gtcatcacgc ttctgtttct tttgaatatg
    10381 ctgtgttgtt gtctctatct ccgtgtagac tttcctcaaa cttatccttt gacagtaagt
    10441 cagtaggctg atttgctctt tctagatgcc agatacattt ctacaaaaaa atagtgattc
    10501 tgttttgaaa attcgatttt tagttctgca ttttcgtaaa catccaacat ttttttcgca
    10561 ctgtatagac ctaacccgcc atttttttta gaggtttttc ctcttttgac catctccgat
    10621 agcgtcaaat tcgttggatt tgccttgttc gctatactaa aacgtgatcc ctctttttct
    10681 tccagcagat tgatcgtaat cggactctga tcggctacac gatgatcgaa tgcgttagaa
    10741 ataaaaatag ataaacagcg aataaaaaca accagatcaa tcgggattgt tttcacttcg
    10801 acaggaataa ctacttggat cgggattttc tccgattctg ctttttctag aaattttaaa
    10861 aagacacccc tgacagctgg ggatacaata tttgttagct gttgtatttg cggtttttca
    10921 aaaatagctg cagaatgatc ttctaatatt tctaaaaatt ccaacgtttc ttttttattt
    10981 tcctgaagag taatttttaa tgaaaacagt agacttttat aatcatgttt gaattcctct
    11041 agatgatggt aatattcttc atttatttga tacagttgaa gcgattcctg atgttgtctt
    11101 tcttttactt ggaaactgat caacataatg gaaaaaaaca aagaaaaaaa actgatgact
    11161 atcgacaaaa gagatagaag cagataatta gatgagcgga agtgaacact tcccaatacc
    11221 aagtaaatca cgccccagct taataaaata caaatacctc caaaatagtg ttcagttgga
    11281 taagtaaaaa gcaagttgag aaatctcgtc tgtttgtcta tactttttac taatagatag
    11341 aaaataaatg cgataagtag tgcaaaaaaa cttgctgttc caagatgtct ctttcctaaa
    11401 taatccatca gatcaaaaac cagaaaaaag ctgagtccag tgatagcaaa aaaaagatta
    11461 ctgatcaaac agctgataaa caggtttttc gtagtaaaat aaaaaagaaa catcaataat
    11521 aagccaacta ggtaaggaaa gctcacttta gggataggaa gtaaaagtgt caccaccatc
    11581 aaagctatac aaccaaagct gttttttact agcagttgtt tcgaaaagaa taaatagata
    11641 cctaaatcta aaatcaaagt aaaggtcaaa taaagtgtca ctgttgcgac catcttattc
    11701 ctccattgtt ttgtttcaaa atgtacacat atttttttaa taggagcctg catatgaaaa
    11761 agtattttat catagaagat aaccagtttc acagcgaatg gatcatcaga gaattggtca
    11821 atcatcatat cgagaatatc gtgcagctca cttctatctc tcaaatcaat cagttgatcc
    11881 agttgggcac tattgataat cacgatgttt tctttatcga tatcgacttg aagcaatcac
    11941 tcacaggtat tgatgtcgcc gaacaaatac gtaaaaaaaa tgcacatagt aatattgttt
    12001 ttttcaccgc ttatacgaat tttgcagtag agatcatcaa tcggaaaatc cttccgattg
    12061 gatatatcag aaaagacagg aatttatctg aacaaattcg tcaagtgcta gaacagatca
    12121 attggaaaga acagcagatc gtaaatgtcg ataaaatctt tattgatcaa aaaggtggaa
    12181 gtctcgtcct gtatcctcgg gaaattttat atattgaaag tatcaaaggt ttgaaaaacc
    12241 aagttatggt caaaacaact acagaagata aattagtgaa tacttcttta aaacaattga
    12301 agacagagtt agaaaagtat gcttactttt tacttttaaa atcttactgt atcaacttat
    12361 cgcaattgca gaaaattgat tctgctcatt atgtgttaga atttttcaac ggtgactcct
    12421 tactcgttgg tcgaaagatc tttgaaaaga caaaggaacg tttccatgac ttccaaaaaa
    12481 ctgcttcgag ttgatgaata agagctgaga cgtaagcata gcagatttca gggagtgggc
    12541 cttgaatcgg ctccactccc tgaaatcgtt gatatgattt tacgcttcct cttctgtagg
    12601 agcatctgtt aacgaccatg tgaatgttga aacgtagttg tctacagcat aattggatac
    12661 aggaacaaat aattccactg attgtctccc ttgttccaca ttctctccta atgaataaat
    12721 ccatgtgcca atcccttcat ttgctcctgc agttactaga tctactgcct gatctgctgg
    12781 gatttcgatt ccttcagcgc cagttccaga aacggtagat ggcattccac tgctattagt
    12841 tgcgctattt cgaatcacgg cgtttttgaa tttcaccttt gaaccagtta gtttattcgt
    12901 atcagatgtt gtaccaataa attctgttcg tttgactgat aatttccaac cggcataatt
    12961 tccgctttta tccgttactt gtacgaaatt ctgtacttgt gtttgtgctc cagtactgtc
    13021 cgttccgctt tgtaatgcag catatactgt ttttgctgta cctaacttga ttgttccaaa
    13081 atcaagatct ggagcttggt caatcgtcag taatccggat gttccctgat ttggttcgtc
    13141 aggtgtaaaa ggagtatcag gatcatttgg atcaacagga ggaactggaa caacgtcttc
    13201 aggatttgca gcatctggtt tggtcacaga aatcgttcct tctgtagtgg ctgagctctt
    13261 attctcagca aaaacacttt gtgtacataa taatagactt ccagctagaa cggtacttaa
    13321 tgcaattgtt tttttcattt ctttttcctt ctttctttta aaataaataa tccagcaaat
    13381 aagccaataa gaatgactcc aacaagtatc agccatcgcc agtcaaatgt ttctggctga
    13441 ttttttaaat caatatcctt ttcattcaat tggtccgctg catcatcagt tatttcaaaa
    13501 tcggtatgga gattccagcg tttttctttc caagcaccct tcacaaccgc ttgataatgt
    13561 cccggagcta atttttttcc ttctaatggg acaagtaaat caaaatttgt attgggtgct
    13621 acatctattt tttctttttt tattgaaagg taaggctctt ttgtttcttt tttgtagatt
    13681 tcaaccgatg tagtcaagcc gaacatataa gaagcatttg gattttgaag attcgcctta
    13741 atcacatttc ttccatcgct ttgatccgca taagcttttt ttaatttcaa atctggggaa
    13801 gactcttttt cgctatttca aatcaagatt gctttcactt gagaaaactg attgacgaca
    13861 ccaactgtac ttttgttaga aacgttctct tttttttctt gaaacgtgat ccctcctgcg
    13921 accacaccag ccagctcttt ttctggcgct ttcagtgaaa gtgtctcagt gaccgcactt
    13981 tgaggaggaa cagttatttc tcccactgtt tttgctaagt ttttcatatc ataacttaat
    14041 gtttcatcaa atttactttt tgattctcca tattcgatca caccgtttga attcgtcgta
    14101 gcggagtgga tcaatgtctc aactgttact gatttatctg ttcggttaaa gaccgtgtag
    14161 gggatttcct gtgttttccc aggctccatc cttacattta tatatgtttt gttcttatca
    14221 atctgattag ccggtaattc aaaatctacc gcaaaattga attcggaggc atggacaggt
    14281 gtctgccaaa ggatgaatcc aaggagaagg atcataagta aagagcagtt gtttcgatga
    14341 cttttattcc atattcgatt catcaatcat cctccttgat ctttattctg tcggcgcatc
    14401 tgctaatgtc catgttatct ctgctgagta attaccagct atctgatttt ctttggttaa
    14461 gacaagttta aacgcccgac cgttatttaa atattctgaa taatctgctt gcacattcgt
    14521 tgaattttgt cctctgacaa tttccagttc ttcttcattc actaattgat actcctctcc
    14581 tttcttgaaa tataggacat cctgcataga aaatcctgca tcatttgtga aaggctgaga
    14641 taattttatc gttaagatcc acggattttt cgtttctcgc tgatcataaa tccataattt
    14701 ttcctgtata tccatttggc caaatgcttc ttgtgtcaaa ccagttgctt tgatctgacc
    14761 aaaatcgagt ttggaagggg caagaaatga gagaccacct tctactacga tcttcgtagc
    14821 aggtgcaaaa ggcggggcat catgataaac aactggcgta tcacttggat tgtgattccc
    14881 aatttcatcg ttggtacttg gcttgttctg cacaccctta gcagtagctt ctcctgcttg
    14941 gtcgtttaat acaatttcta atacatctcc tgcaaaaagt tgattttctg ggatagaaag
    15001 aacaaattcc cctgtatcat caatagttgt ttctgacaaa acagcttgat tttttttcaa
    15061 tgaaaccaag gctcctgctt cacctgtacc tgtgatcgtg cgagaagctg cattgatcaa
    15121 tgtggtactt aaattagcag gttcaggagg aatcacatcg actgtcgttt tggcagagtc
    15181 cagttctgtc acttcttggc cacctcttac ttttttagca gcaacaactt gcacttgatc
    15241 ctccgttttt aatctctcat cattgggtac ttgaacttcg aacaagccgc cttgttcgcc
    15301 ttctccccat gggttatatc ctgccccttc attttcatct gtttgtcctt gcgtgagagc
    15361 agtaatttct acagatgatt tcgtcgtatc tgcgtaagta atacgtaaag tcacttctac
    15421 ttcgcctgtc caagcatctc ttggctttgc ctcgacacct tcgggaacaa cgacatgccc
    15481 atagattttt ttatctgcat tcgttggcac tcttaaggat tcaatcatcg ggagctgatt
    15541 attggcactg attcgattat aatttttcat tccggcacct gtctgagcaa attcatttgt
    15601 taaacctgca ctagggcttg atacgaaatt gcctaagtcg gtcccattga tcgataagtc
    15661 tgtcatatca gaaaaataat ccgggtcttt ttcaaagtta tcgaatgttg cgcctgtttt
    15721 tcgccataaa gcgatttctg aatgggcgat ctttaaagaa gaatctccat ttccttggaa
    15781 tacccagccg cctatgccat tggtctcgct tccaatccgt ttgttttgga aatcaaaata
    15841 ggtaggagat tctaagtcca cattcaacac atccccactg atgatgccgg tcttatcttc
    15901 ccctgttttc ccgaccatga ctaaataagt tttttcacct gccgtaaaat ttaaatcaat
    15961 atctccagtt gtatctacag ttgctccgga atctgcgcgt atatcgatat ttgatttttc
    16021 tccagtgact gtaaaatcag ctgaacctgg actttctaga aaaccagaag cgtcataaaa
    16081 ttggatcgct tgatttcctt gattgagtct gttcacgtaa gatttgccat cacctgtatt
    16141 tcttaccctc aatgagcctc cattggttac tgtcagcttt tgcgtaccat tctcaaaacg
    16201 aactgcgctg gaacgcccac tctgcttatc gatgtcgata actgatccgg ctccttctac
    16261 gatcaaagaa aggccttttc ctacaaaacg catcccattg ttcccgggtt gatcgtcatc
    16321 tccagccatt ttgaccgaga tttgtccacc acttgataca tggatttgac tagaatctcc
    16381 ttgcaagcga aatccgcccg tagttgctgt attgatggtg attttcccac cattcgatac
    16441 agtgactttc gatcctgaac ctctcatttg gatgattccg cgattgttgt cattggtaat
    16501 attgatcttt gtatttaccg aaaattcgct tcccgaacca ctgacttcaa acatgacatt
    16561 accaggtagc gtatcgactg cctctccttc atcgctaacg ccatctgccc gatcataatc
    16621 aagagagacc tttgaaccgc ttaagatatg gattcctggc gctgtttttc cactaccagt
    16681 ctcatctcct gaatctagaa aaccgtagaa tttccctaga tacggtccat aaagttgact
    16741 accattgatc acattcaatt gatagcttct acaaaaatag gctttacccg gagcggcatt
    16801 cagtccttcc ttcactggtt ggacatccaa cacaccggaa acaccatcta atgtgacagt
    16861 tgcacgagga gcgtaaatca gtcctaattt ggacccatca tacaaatcaa gtgtcccggt
    16921 aaattttatt tctcccgtaa aatgatatct gcttccccaa aaatcggtca tataagcaat
    16981 gataatggca tttccatcga tatttggtgt caatccacct ggatgtgcag ctgttccttt
    17041 aaaattctgg aactcgatcg actgaggtat ctcattgata taaatatggt gtgtgccgaa
    17101 attgtgagcg aatccaccaa aatcaataac gatatctcgt ttgatctcta attccctgtc
    17161 taaagtcaaa ggctgaatca gtcggatctt agttactgat tcgtctgcga gaagctgcgc
    17221 cagttcttct gttgtggcag cttcgctgta cccatccgtt gaaacagctc ttgccagtgc
    17281 cgcttcactg ctatcagacg tttgttcagc tacttctgag gtctcacttg tcttattttc
    17341 ttcttgcctt ttattagtag aagcctcact ttgagattct gtagtttcag aagtaatcga
    17401 ttcttctgaa aaagtagtct tgtcaaaact ttgattctct gattgcgttg attcgtttgt
    17461 tttctctaca tcggcaaaaa cggatgtcac catcaagaga gggaagacaa acaaaatcga
    17521 cgcaatcagc ttttttacac attgattcat tctccaccat cctctctgac gttttgacaa
    17581 ttttatttta tcgttttaat ctatttccaa ttgtactttc atatttaaaa tatgtatttt
    17641 tatggaaaaa tttttctatt aggtgtaaat ttcttttttg tacaaaaaaa aggctgtgac
    17701 aaaagtcttg tcacagtccc ttatcccgaa caagcggtgt tctcccgcca actcctcggt
    17761 cacaacctcc attttaacaa taaacctgta aatgtgaggg caatactttg attgtcacag
    17821 gtaatttatc cccttcatct ccatcaacat tcgtcgtcaa ttcttcctca tcagctaatg
    17881 acacaactaa ttgctcacaa gtaaggtagg ctagattttt cgtagattca tctactcctt
    17941 ttaataggtc tggcaatgtt ttaagcgtat cgatcaaaga agaatctttt aaataaacca
    18001 aatggagctt accatcatcc acttttgcat ttggaagtaa tgtttcaaaa ccgccgactg
    18061 agttagttag tcctatcagc aaggtactgc tctcaatttc ttccttcttt ccatcaactt
    18121 ctacgtgaaa cgagtaggat tgtgtggaag ctaactgttt gattcctgac atgaaataag
    18181 ctagttttcc aaatttcgtc ttcttctccg catctacatc attgattgat tcagggatag
    18241 agccaattgc gacgacattc ataaaatagt cgtcatttat ttttccaata tccaatggct
    18301 tgactgattc aatcgaaaaa tgattgatcg cttcctcagg ttctagcggt atccctaatg
    18361 ctcgagccaa gtcattcacc gtacccaatg ggaaaaatcc gaaatttggc cgatgttctt
    18421 gttcagcgat tccactgatt ccttcgttga ctgttccatc tccgcccatg acaaacacac
    18481 tatgataccc ttccgtagcc gcttcgcgag taaagttttt tgcatcccct gctttttttg
    18541 tatgcaagac gaccacttca tcaaacaccg attccaattt tgctatcgct aattgctcaa
    18601 attcctttgc ttgttcaccg cctgaactgg ggtttaccac taataaaact tttttcatca
    18661 ctttctttcc cttctgattg atttctttaa tataacgata gcataaagaa aaaaattagg
    18721 ctgtgatgaa gtactgttca tgaaacattc atttattttt tgacaagata aaacatccat
    18781 actatgaaac tgaggaaaat taaaacaatg atataggaaa taaaagaaaa tgataggcat
    18841 tgtataccta ataaagtaaa aatcttaggt ggcagataaa aacacaaaaa tagcaagaga
    18901 atgtaatagc gtttcttcca ctttttgtta tcagacctta tagcgatcag aggaatacca
    18961 aatgcataac tgaaaaactc ttgatgtact gttaatatgt cacggccttg aataataaat
    19021 gcgacaatcc ccgctataat tagtgtgcct aacaccaaaa cggaaaattg atgaatatat
    19081 tttatataca aatgatccat tgtacttcct gcctttttat ttgtgagaaa aacaaatccg
    19141 tatacgtgaa taacttctag aaataaaaga aatttgcaaa accactccat ttatctactt
    19201 ctacgtgcat tttttgatat tgttttcttt atttaagatt atacagaaaa atatctaggg
    19261 tcgctggatt ctaagtaaaa aaaattttta aaataaaaag aactaaatca agtagtaatt
    19321 aaactactgt tgatttagtt ctaataaaaa gatttagatg aacagtttta ttgatttaaa
    19381 tagttcatat tttttattta taccgcttat ttactacttg ctgtactaga atctgaagtg
    19441 aatgtactca aaacattttc aaagtctttg tctttgattt ttacattagc gtctttcaat
    19501 acttcgccaa ttactttatt ctggaaggta ctgtcactta attttgtgtc tgttgcaatt
    19561 tctttcaatt cttttttgta tttatccatg tcgttgcctt tgttttggtt ttccaccatt
    19621 ttaaccacat aatattccgt agtataagtt gaagcattgg tagaagtgat cacatcagaa
    19681 acttgaccat ctttcaactt aaaggctgct tctttgactt ctgccggaac cgttgtagta
    19741 gtggaatcaa atttcacttt tccgccatct tcttttgtcg tagtatcagt tgacttgtct
    19801 ttggctaatt tagagaaatc gtctccctta tcagcagctt tcttcacatc ttttgcatca
    19861 tcttcacttg ctacttggat aatttgagct tccacttctg gatggaaaga ttcccaagcc
    19921 gtttttaaat cttcatcggt caatttgata tgtttcttta gaccttcttg aaaggctaga
    19981 ctttgtttga tactgtcttt gaatgtttgt tctgtgtaac ctgcagattt caattgtgaa
    20041 tcaaatgaat cacccaattg tttctttgtt tgatcatatt gagaatcgat ttctttggtt
    20101 gatacgtcat ctccatattt atcttcaaat acttgataaa cgatcaactg ttgcacagcg
    20161 gaatctgctc cttgcatttt tttcaagcta tccattactt cttgttcgct gattgtaccg
    20221 cctttataac taacggctgt tttttcaccg gcattcgtac agcctgacaa taagccagtg
    20281 cctagtacga tggcaagtgc taaaaatctt tttttcattt atcaattctc ctacttttcg
    20341 ttttttgcga attgctaaaa acaaaggtgt tcaagatgaa aatcatcaag aacaccttta
    20401 ctaatctgct cgatacgtcc tgaatagata taaggctaca caatccagaa agttcgctca
    20461 gcagaataaa tgtcaagtag cacatcacac cttaatatac tacttctttt gttaccgttt
    20521 ttcaagtcta tcttgcgttc cgtatttaac gtaactaatt cttagaacaa atgttatcga
    20581 ttttgttttt cttcttccgc tgctgggata ttcaaatcag acacttttat gttcgatttt
    20641 ccagacattt ttttgttgtt tttattatga tatattttta tacaactaaa aatgaatata
    20701 ttaaaactac caaaaataac ttttaacgct gtttcattat atgttttttc tattttatat
    20761 aaacttttgg atacttaata ccaaccggtt ggattgtacc aacatgagaa tgtgtcagtt
    20821 ctatttcctg tcgcacttgc ataggcccat actccttttg ttgcatttgc tgatcgaata
    20881 gagtttccaa ctttctcttt tgcaccgtga cgattataga cacgactata gtggttagaa
    20941 tgacctgttt ttctcgtaca agttgtatca ctataataaa cccatcttcc agagctatga
    21001 ttaattgctg ttctagaaat ttcccggtct actggtaaat ttgacttaat aatattacct
    21061 ttagcatcaa aatgaatctc tcctggcttt aaagatttgt aatagatttc accgtgaact
    21121 gaatttgctt ccacttcaga tgacatagcg tttcctccaa caaaacctat ccctagtgca
    21181 caaataataa ctgctttttt cataaaacga catcctttcc tttttgattt ttaaagcatg
    21241 atcttcttgt ttcctatttt ggtcagatat ggatcatgcg tgactacgat aactaacgta
    21301 ccttgggaag cttgttgcga taagatttca actactttat ccttatttct tttatccaat
    21361 gacccagtcg gttcatcggc taaaatgatt ttgctattct tcaataagac tctcgcacag
    21421 gcgattcttt gcttctcacc accagataat gtgtagatag gcgtacttag cttcttgttt
    21481 atatttactt ttttcaatgc ctcatacttt gctgttcgct tatctgaaac atttaaattc
    21541 gaaaacttca atccaatatc taaattaaaa tcgattgttt catattcaat caacccaaaa
    21601 tcttgaaaaa gaaaagatat ggtatttctt tttatcaagc gcttctctct cccagttaat
    21661 tgtttcgtct cttgatcgaa caaatagaat tgtcctgaac tgaactgatc attcaatcct
    21721 aatatattca ataacgtact tttacctgct ccactttctc caacaacagt cacaagatcc
    21781 ccagcatccg cagtgaaacg atccaaatga agaatcgttt tgtttcgaat gatttttttc
    21841 gcacctttta tcactatcaa cggctccaat tgttaacctc cattcatcag caataactga
    21901 cttttctttt ctgtagacaa aataaaaaca actgaaagaa taaaatcaat gaagctaaag
    21961 aaaaaaatat taaaaagata tttaggctct ctttctataa gaaaaaggaa gattacactt
    22021 gtcgttcccc atttgatgag gttcatcatg aagaaatctt tatacgtttc aaagagcgaa
    22081 taaccacttg aacgaaagat agcgattttc cgacaattgt agacaaaata tatgcataac
    22141 atgacatagc tcaacaagaa gaaagaaaag aaagtgagta aaaatatctg tatcaagtaa
    22201 tgaaatgatc tgcttaacac tttgacagct atctcttcag tctgagtata cggaaatgat
    22261 aactgcaagt tatcacgtaa ctgactttct tcaatcagct caaataacct ttctttcgac
    22321 aaagagccta tcttgatctt taacggtgga tagatttctc cgctgagaat atttctttcc
    22381 aaatacatac tgtttttcaa tgtcagtatt tcaacaaccg gataatgttc gatccagggg
    22441 atagaaggaa taaatgtata aatgggttga ttgtttttta taaatagaaa tttcggttct
    22501 ttttcactga tttcttgata atattctgtt atttgcgcca ggtcattttt taaatctgta
    22561 tgtctatatc gttcagggat caatataaca gggtgcgttt ctttttcggt tatttggatc
    22621 aaccttccag agacatcaat caaaggaaat ttcttaagat aattcagatt tatttttatc
    22681 cctctgccaa actgttcatt ttcttcattc aagtaatctg atacattgac taatatactt
    22741 ccgtttttat tcaaagtttc atataattcc tgatctgctg ctgatgcaaa acgattggaa
    22801 taaataaaat ccacgtggtt tttcccgatg gttactggat aaaatacatg atagtcctca
    22861 ccagcgattt cttttggtgg ttcatgggaa acagctaact gtgaagaaga aaaaacgata
    22921 gttgctaatt cgacattggc aacggtcaaa agaagagaaa acaacaatcc aaatgtaaaa
    22981 agaatgtatt ggatatagtt gaacgcttct cttaacgaag cgattttttc aactaataaa
    23041 agagaaatca aagagatacc atatattccg ctgaacaaga aaacgtacat ctggaacaaa
    23101 taaagaaatt gctccttata atacataaaa ataaaaccac caatgattcc tgcaattatg
    23161 aatgtaataa tgattttctt tttccccaat aaacaccaca atacttgatg taatgaaaag
    23221 tcattattca acaataaact gatttcttta ttcatcaata agaaaaagga tgataacaaa
    23281 aggaataaaa gaatcaatcc aatagttaaa tacactcgat aattatatac gtctgtattt
    23341 gaaataaccg aatacgaata gctattttca aagtcttcaa aaatattagt ggcataatca
    23401 gtgtgaaatg cttgattgaa tcgatcagtg aatagtgaaa tgaaccgttc ataggcttct
    23461 ttttctctcg tcatcaagaa aaattcacct tcaaaatctt ttattttgat cgattcttca
    23521 atggacgtta cgcgaaagga ggtattagaa tagggtacct tctcgtgaga agatttgaca
    23581 tccccttgat aatacaatgt catttcaagc tttggctgta tcttgaagtt ccaagatgta
    23641 tctacttcat tggattcatt tactgttttt ttcatataag aaagctcagt ttctgatgag
    23701 acattttcaa ataccatgat tagctgctca tattcttctt gcccaataaa atgttgtggc
    23761 aatcgaatcg gagtataagt atctgtttga tggaaaaatt catttgtccg atagagtacc
    23821 tgtttattta tactaaccaa ggcaaaacca ctcatgatac cggtcactat gattgtgagt
    23881 aaaactgtga actttttttt gattatcacc actctccctt acttaaatga ttctttgata
    23941 aaatcatacc gtttttcatc aaaaaaacgt atctatcaag tgtataggtc atgtagaata
    24001 aatctatata ctgtagaatc gaaaggagaa gaagatgaac accggagaaa aaatacgaac
    24061 ttaccgcaga aattgtaagc ttacgcaaaa agaattaggc gaaaaaattg gtgtttccga
    24121 taaaacgatt tctagttggg aaaattctcg tacaatgcca gaccttgaaa tgctgtcact
    24181 tttacatcat actttaggtc tgccgattga ttttccttct attgaatcag ctaccgaatc
    24241 aatagaacca acattgccag atgaacctct tgttaacaag aaatcttatt catcaaaaca
    24301 acccttctca ctcaaaaaga cactatcttt ctttctgctc gtcttttgtt tggtctatct
    24361 ttttcttatc aattatcaat acaaaaatga aacgatcgat cgattcaatc cttttttgaa
    24421 accacaaatc ggctatacca cactccctgt aggatacgtg gacaattcca tcgaacgttg
    24481 ggtatgtaat gatatctttg gccatggtac atggctgtct tttcacgctg gagaggtaga
    24541 aaaagagaaa aaccatgctg taatcaaaca caaaggaaaa cacgtcatga acgttcgcct
    24601 gctcacttgg gaagccattc cctcagatta ccaagaaatc ctcagccaag actatgacga
    24661 cgccttaaaa agaagccctc aggagccaga taggcattaa gtaggagatg aacgtagaga
    24721 tagaaaaaat caatgcacat gatcttatcc aaaaaacagg ggtacaaatt aattgaaaaa
    24781 gccttgagat gaaagttcct aaataaaaaa gttcagaatg ataggtattt ctggcttata
    24841 gtataatatt tacgccacag cctcccaatg attctttttg gaatcataat caaggatgga
    24901 cattcacaaa aatattttgc tcattcgatc cgaatagatt aacgaccaat ctagtaagta
    24961 atatagattg gtacgtagtc aagctgcaca taatttagat caattttagt tcttttttat
    25021 atttctatga tctgctcatt tacttttata tgatggctta cagtaacata aataaatatg
    25081 ataatcgctg gtagtttatc caagagtact caataaaata caaaatggat tgttcaagcg
    25141 cctatcataa tgataaaatg aaacaaataa acgatacaag gaggaagaga ctttgagtaa
    25201 tggcagaaca attttttcat tgtaaaaatt gttcagttgt taatctatgg gatttcggta
    25261 gcatgggcat ttttttatag aggaatcaca ccaacctggc cgttttatct cttgttagtg
    25321 ggaatattag taggaaattt tgcccctctt cactatcgta cgaacttttt tccaactgat
    25381 tctggccttt ttcttaaaac aaagacgcga aaattagaaa acattattga aatgacaatt
    25441 acctgtataa tcattttctt agttatattc ctaaacgtct tctaataaga atctcttaaa
    25501 attagcttgt tacagttagt tacctagttt atataacaca gttatcttat cttccttatc
    25561 aacatctttt gccaactctt tgtcttaaat tcgaaacata taagcagagc tacgaacacc
    25621 aagactgttt cggctctgtt ttttgcatca aattcactct tatatagctg ataatctcgg
    25681 ctctttaaaa gaaattattt tcgcttcatt ttattataaa aaggctagga accttgatgt
    25741 tatcaggttc ctagccttta tttaagtatt accccacaga cccttccatc tcataactga
    25801 tcaatcgatt gagttcgact gcatattcca ttggaagttc tttggtgaat ggttcaacaa
    25861 agcccatgac gatcatttca gttgcttcag attcggtcag gcctcggctc atcagatagt
    25921 agagttgttc ttctgagatt tttgagactt tggcttcgtg ttctaaagag acttggctgt
    25981 tgtggatctc attgaatggg atcgtatcgg atttcgacca ttcgtccatg atgatcgtgt
    26041 cacattcgat atgagagatc gaacccgcac tgtttttggc aaaggttact tgtcctcgat
    26101 agtttacttc tccgccgtct tttgaaattg atttagagac gatagagcta gatgtatttg
    26161 gtgcattgtg gatcattttt gcacccgtat cttggatttg gtttgctcct gcaaaggcga
    26221 tggagagcat ggtgcctcgt gcaccttttc catctaagta aacacttggg tatttcatcg
    26281 ttgtttttgc acctaggttt ccgtcgatcc attcaacggt tgcgccttcg tatgcttttg
    26341 ctcgtttggt tactaagttg tacacattgt ctgaccagtt ttggatcgtt gtgtaacggc
    26401 aatacgcatc ttttcttgta aagatttcta cgatggcggc atgcaggctg ttacttgaat
    26461 aagtaggtgc cgtacaacct tcgacatagt ggatgcttgc tccttcgtca acaatgatca
    26521 gcgtacgttc gaattgcccc gtgttttccg cattgatccg gaagtacgtt tgtaatggaa
    26581 catcgacttt gacgcctttt ggcacgtaaa taaaggtccc acctgaccat acggctgaat
    26641 tcagcgctgc taatttgttg tcggttggcg gtacaagttt tgaaaagtac tctttgaata
    26701 attcagggta ttctttcaaa gcagagtcag tgtcagtaaa gacgattcct aacttttcga
    26761 attcatcttt catattatgg tacacgactt ctgattcata ttgtgcggaa gcaccggcta
    26821 gataagctcg ttcagcttct ggtataccaa tcttttcaaa tgtatctttg attttttctg
    26881 gtacgtcttc ccagtcacga gcgggtttgt cacttggttt ttggtaatat ttgatggcat
    26941 cgaaatcgat gtctgaaagg tcggggcccc atgtttgcat tggcattttg ttaaatgttt
    27001 ctagagattt cagacggaat tcaagcatcc attctggttc gcctttgatt cttgacatct
    27061 cacggatcac ttcttctgtc aagccttctc ctgtactgaa aaccggttcg acatcatcgt
    27121 gaaacccgaa tttatattct tctaattctg gtacgcccat gttctcactc ctcttccttg
    27181 tggtaatgat ggaaagctgc ggtaccatcg ttttccattg cttttcctag tgctttccag
    27241 gcaagtgtcg cacatttgat ccgagcggga aatttagcta caccaccaag catagcagca
    27301 tcgcctaatt ggtcgggatc tttgacttct tttccttgga caagctgtag aaagtctaca
    27361 gttaaatgtt ctgcttcttc tattgatttt ccgatgacgg cgtctgtcat catcgaggca
    27421 cttgccgtac tgatggagca gccactgccg tcaaaggcga tatttttgat gattccgtct
    27481 tttacatcga cttgcaattc gatcacatct ccacatgtgg ggttgttcaa ttcgatcttg
    27541 cttgtcgagt cagtcaagct tccacgatga tgcggatggg aagaatgatc caagatcact
    27601 tgacggtata aattgtctaa tttagatagt cccatgttgg aaaaactcct ttgttgccat
    27661 gattgcttca actaaacggt cggcgtcttg cgttgtgttg tagaaataaa agctcgcgcg
    27721 agcagtcgct gatacttcaa ggtacttcaa tagcggttgc gcacaatgat gacctgctct
    27781 gacggctacc ccttccatgt ctaaagctgt cgcgacatca tggggatgta acccatccaa
    27841 attgaatgca acgactcctg tccgaaaatt cgggtcttgt ggaccataaa cagtcaatcc
    27901 atcaattgct tgtaattttg gcaacacata agcggctagt tcttcttcat atcgatggat
    27961 attgtccata ccgagttttt gcaaataatc gattgcatgg cctaatgcga tagcgccggc
    28021 gatatttggt gtccctgctt cgaatttcca aggtagttct ttccatgtac tgtcgtataa
    28081 ttcgacaaaa tcgatcattt cgccaccaaa ttcaacaggt tccatttctt ctaaccattt
    28141 tcgtttacca tataaaacac caatacctgt tggtccgcac attttgtgtc cgctgaaagc
    28201 aaagaaatca cagtctagtg cttggacatc aatggccatg tgcggggcag attgagcacc
    28261 atctactacg atgaccccgc cgttttcatg gacaagttca gctaattctt gaacaggatt
    28321 gaagacacct aagacattgg atacatgagc aatggagacg attttggttt tgtccgtaat
    28381 ctttttcgct gcatcctcca tatccaggaa gccttcttct gttagttcga tatatttcaa
    28441 gacagcacct gttcgttttg ccaactgctg ccacgggata acattagaat gatgttccat
    28501 gtaagagagc actatctcgt ctcctgcttt gatatagcgg tcgccgaagg ttctggctac
    28561 ccaattcaag cttgtcgtcg taccacgagt aaacagcact tctgctgttt cttttgcatg
    28621 gatgaacgcc cgtacttttt ctcttgcttg ttcataatca tgggtcgcgc gttctgctaa
    28681 cgtatggaca ccgcgatgaa cattggcgtt atcgtgttcg taatagtacg ctaatgcctg
    28741 gagtacttgt tttggctttt gggtcgtcgc tgcattatcc agataaacta aaggttcatc
    28801 attgacgtct tgaaataaga taggaaaatc attgcgtagc tttttagcat cgatcatcca
    28861 ttcaacttcc cttcgattac ttcgactaat tctttccgaa cttgttctac agggattgct
    28921 gttaagacag aaccgaggaa tcctcgaatc actaagcgct ctgcttcttc tttatgcaat
    28981 cctctactca tcagatagta catttcttct ggatcaactc gtcctacact ggcagcatgt
    29041 ccagcagtta cttcgttttc atcgatcaaa agaataggat tcgcatcacc acgtgcttta
    29101 tcagaaagca tcaagacacg actttcttgt tgggcatctg caccttttgc ccctttcaag
    29161 atgtggccga taccattaaa ggtcaatgtt cctttttctc ggatcactcc gtgttgcaaa
    29221 atatgcccga tcgtatgagg ggctttattg gttactcgtg tatcgattcc ttggatttgt
    29281 ctgcccgagc tgattgccac gattttgact tctgcgtgtg caccttctcc tgctaaatct
    29341 gagtcaaagt cagcgatcac atgaccgtca ttcatgacac caattgccca gtcgacagaa
    29401 gcatctcgta aaatgtgccc acggcgattc atataagaag taatattttc tcctaattga
    29461 tctacggctg aatatttgat ttttgaacca gctttagcga tgacttccac gatgatatta
    29521 cctgatgatt ttgctacttg ttctttggtt gtctggaaac gttccagata agaaaattca
    29581 ctatgttcat ctgccacgat caacacatgc ttgaagaagt gctcatcgga tgcgccatct
    29641 tgaatgaata aggactcgag tggttcatcg atcacgacat ttttaggcac atacaggaaa
    29701 ataccgctgt tcataaaagc tacatggagt gcagtcaatt ggtcttcgtt catgtttact
    29761 gcttttttca tataatattc ttggactagt tctggatatt cgatcattgc agtgaacaag
    29821 tcggtaaaaa tgactccttt ttctgctaat tccacaggca gttgttcaaa aatcgtccat
    29881 gaaccttgtt ggacaagcac aggattgtct ttcattgcat caaatgccgg aatcgtgcct
    29941 gtttcactga tggtttgtgt ttctttcaca tcaaataacg accagcgatg gaatttcacc
    30001 cgatcgatat gcggcaatgg cagttcatct gctttcgcta gtgcgtcttg acggaaggtt
    30061 ctcatccaat caggttcgcc tttacttaaa gaaaaatcat ttaccgcgtc aagataatcg
    30121 agccagtttt tttctttcat tcttgctccc ccttacgctt cttcttcttt atagtcgatt
    30181 cctaattctt tactgatacc agcgtagcct tctgcttcca gacgtttagc taggtcagca
    30241 ttccctgtca tgactactcg gccttccatc atgatgtgaa cgacatcagg tgtgatatag
    30301 ttcaataatc gttgatagtg ggtgatgatc aatgcaccga aattgtctcc gcgcatttca
    30361 tttactcctt tagcaacgac tttcaaagca tcgatatcca gacctgaatc gatttcgtct
    30421 aaaattgcaa atgtaggttc taacatcaac aattgcagga tctcattccg tttcttttct
    30481 ccgccagaaa aaccttcgtt cagataacgt tcagccattt cttctggcat atttagtaaa
    30541 gccatttttt catctaactt tttcaaaaat gccataacag aaattttgtc gttttcatca
    30601 cgtttcgcat tgatcgctgc acgcatgaat tccgcattcg tgatacctgg tatctcactt
    30661 ggatattgca tagctaaaaa taagccaagt cgcgcacgtt catctacttc caagtctaaa
    30721 acatttttcc cgtcaaacaa aatttcgcct tctgttactt catagtttgg attgcccatg
    30781 atagcggcag ataaggtaga ttttcctgtg ccgttaggtc ccatgatggc atggatttct
    30841 ccggttttca ttgttaggtt tacgccttta aggatttctt tttcctcgat cgacacatgt
    30901 agatttttta tttctaagac agacatgcat tataccccca aattctcttt cgttctcact
    30961 cattttagac taattgagaa tgaagcgcaa tgaccttcct tactaaaatc aaatatcttt
    31021 tatttattat taaacaattt tgatttctaa attagaatag gtataaaaaa gatgagaaat
    31081 aagccattac agacttattt ctcatctttt ttgttccata ccttattttg catcagcctt
    31141 tactggttta acagagccgc cccatttgtc tgtgatccat tcttggactt ctttgcggtg
    31201 aagcacttca atcagttttt tgattttgtc actgtcttca tcacctttac gagtcgcaat
    31261 aatattcacg taaggagagt tgtccttttc aagcaatacg gcatcttcta atggattcaa
    31321 ccctgcgccg taagcgaagt ttgcgttgat tgcaactagg tcaccttcat cattttggta
    31381 cgtagaagct aaaagtgatg ggtcgatcgt atggttgaac ttcaagttct tagggttttc
    31441 ttcaatatca tcgaatgttg ctgtttccag atctactcca tctttgactt tgactaagcc
    31501 agcatcttgt agaattgtga tgatgcgtcc ccagtctgat tcagaatttg aagtaatgat
    31561 tgttgcacca tcttttaatt cggaaacatc tttgactttt ttagagtaca agcccattgg
    31621 ttcgatgtgg acagcaccgg cattgacaaa gtcatatcct ttttctttga tttctttgtt
    31681 caaataagga atatgctgga agtaattggc atcaatgtcg ccttcttcca aagattggtt
    31741 cggtaataca tagtcatcga atttgacgat ttcaagatcg attccttcat ctttcaataa
    31801 tggtttcaca tgttccaaaa tctctgcgtg cggtgtcggt gaagcgccga ctttcaatgt
    31861 cgtgtcgtct gctttatttg ctgaatcttt gctgtcgctg ttgttaccgc atgctgctaa
    31921 tcctacagtc agcaaaagcg ctgctgcaaa tccaaaaatt ttctttttca tatcctacat
    31981 ccccctatat cctattatct tttgtctgtt ttcttagtta agaaatcacc gattccttga
    32041 acgataaata cgattagtaa aataattaaa gtcgcaacga atgtcactgt tagattacca
    32101 cgctggtagc cttcctgcca agcaagacct ccaagtccac ctgcgccgat cgcgccggcc
    32161 atcgcagtaa atccgatcat cgagatcgtt gtaactgtta atccagaaat caatgcggga
    32221 atactttcag gtatcaagac cttccagatg atttcccagt aacttgctcc cattgcatct
    32281 gctgcttcca gtacaccagg gctgacttca cgaaaagcaa tctctactag acgggcataa
    32341 aatggtgctg cggataaaac aagagctgga atggctgctt gcgcacctag catagtgcct
    32401 acgattgctt tagtaaatgg aatgatcaaa accatcagga tcataaatgg cgttgaccgg
    32461 aaaatattac tgatgatcga tacgattcca taaatgattc gagcatacgg tttgtttttg
    32521 cgtccaatag agtaaaggat caatcccaaa actaatccga tgatcgtcac taagaccatt
    32581 gagattaatg tcatatatag tgtatcaagg atagcctgat tcatcgtttc cgggttgatt
    32641 tgtttaaaat ctagatatgt ttctgaaaag cttttatcca cgatggatca cctcaattcc
    32701 tactccttgt tctttgatga acacttctgc ttgatctaat tctttggttt caccagtcat
    32761 caagacagtc aatgaaccaa aggaaccttc tttcacttgt ttgatctttc catacacaac
    32821 gttgacatcg atgttatagc gtcgaatcgc ttgggaaatg actggctcgt tggcatttct
    32881 ttcgctaaag gtcaaagttg ccaaacggcc gcttggattt tctttgatga gttcagctaa
    32941 tagttctgtc gaatcagctt ctggttcgat gtcttgttgt acaaagcgtt tggttacttc
    33001 ttttttcggt tgtctgaaga cagtcaatac gtctccttct tctacgactt tccccaactc
    33061 catcacagcg actttgttgc agattttgcg gatcacattc atttcatgtg tgatcaagac
    33121 gatggtcaaa ttcaatttct tattgatcgc taacaataag tctaatactt cttctgttgt
    33181 ttgcgggtcc aatgcgctag tagcctcatc acaaagcagg atctcaggat catttgccaa
    33241 tgctcgtgcg ataccgacgc gttgtttctg tccgccggaa agttgtgaag gatatgcttg
    33301 tccgcgtcct tctaacccga ctaaacgcaa cagttcttct gcccgttctt tacgtttgct
    33361 ctttggtacg ccagctaatt ccagcggcag ctggatattt tcaagtacag ttcttgacca
    33421 taacaggttg aaatgctgga agatcatacc gattttcttt cggaatgtac gtaattcttt
    33481 gttttttaat tttgtaatat cttgatcgtt tacgatcact tcgccgctcg tgggaagctc
    33541 aagtccattc aggagacgga ctaatgtact ttttcctgcg ccagaatagc cgacgattcc
    33601 ataaatatcc cctttttcaa cgtttagtga aacgtcattg acggcttgga tgtttccgtt
    33661 tttcccattg aatgtctttt tgacattcgt tagttggatt aatgacatgc cattcacatc
    33721 tttctcttat gatttttcaa acaaaaaagc cttcgccctc ttgccttaag caaaaggacg
    33781 aaagcttgaa cttccgtgtt accaccttga tttaccgtta cttcgcaata acagcctctt
    33841 ccagtacttg gacttagctt ctttccgtat actgtcgcgc tgtaacgggc actcccgtag
    33901 taagtttgct tacgctcgct tactctgctc taagaccatc ttccatctca ttttcgttac
    33961 ccattttcag caaacagggc tctcttcaaa cgtccgtgac atgtactctt cttttcaaag
    34021 ctttctcgtt tcatatagga ttgcttatga ttatagcaac tggaagaatc agtgtcaact
    34081 tttttcaagt gattttctga ttttataatt cgtcaaattc ttttggatca acatctttga
    34141 aacttaagat ccacgcattc atttcatctg aatcattcaa gatattgata tcttcaccga
    34201 ttttatcatt aacagaagaa actgtacccg ttagcgggct ggcaaattca ttgaccgctt
    34261 tttccgcttc aacttcgatc agaggttcat ctttttttag cgattgtcct gcttttggca
    34321 gattggcaaa cgtgatgtct ccaagttctt cttgcgcttc atttgtcaaa ccaacacagt
    34381 attcttttcc attaaataag atccaaaggt tgtccttttt cttcaaatgc ttgcctgcca
    34441 ttttatatca gttctccttc ataaattttt tcattgaatc caattgcaac aagctggtcc
    34501 tctcgtaaga tcagtggtcg cttgatcagc ataccatctg tcgataagac ttggctcgct
    34561 tttgaagccg taaactcgcc tacttgatct ttcagtccaa gttcccgata tttcatcccg
    34621 cttgtgttga acaggcgacg gattggtact tgactcgttt ctagccaagt ctcaatcgtt
    34681 gaggccttcg gtacttcttt gatcatatca acggtttgat aactaacgcc atgctggtct
    34741 aaccacgctt tggctttttt gcatgttgaa catttcgggt accagtaaaa ggtgtacaat
    34801 tttcttacct ccttgaagat cttgcaggtg cttcattttg gtatctcatc gataatatca
    34861 acccgatacc gatcatgttc cctaaaatcg aggatcctcc ctgactaatg aaaggcaatg
    34921 ggatccctgt taaaggaagt aatccgatat ttgctccaat attctcaaag acatggaaca
    34981 gcagcatcat gatcaaaccg cttgcgatat aggcgtaaaa ttcattattc gtatcgaaac
    35041 acacccgaat catacgatag attaaaataa aatacaagaa aatgacgaat gcaccaccga
    35101 taaagccgaa gttttcaccg ataacggtaa aaatcatatc ggactcacga acaggcacat
    35161 agatattgct tacgttgaat cctttaccaa acaagccacc ggtaccaatt gccaaaagtc
    35221 cttgggccgg ctgataactc attcctgacg tatcatggaa agggtccagc catgaatcaa
    35281 tacgtgcaaa ctgataagat ttgaatccaa ctttataaag caagtctctt ccgccttcag
    35341 tcgtaaccaa gaagatcgtt cctgctccaa cgactactgc caagattact acaggtgcga
    35401 tgatgcgcca agagattcca gacatcagga aaatcccgcc aaagatcgca agaaagacaa
    35461 gcatcgttcc aaagtcatct tgggccatga tcaatgctaa aaccggtatt gtcacgatca
    35521 agagcttccc aatcagccaa aagtccgatt tcatcgtccg ttcttttact tgcgtattat
    35581 gtttagttac gatcagtgcc atcatcaaga tgtacgcaat cttcatcaac tctgctggct
    35641 ggaaagtaaa cgcaccgaat cgaaaccagt ttttagaccc tgttgaagca gctaaattct
    35701 gatcatagaa tttgagcaag agtcccatta ccactaaccc caaaccataa aggtaaggag
    35761 tcagtttcca gatccatttg gaattcaaat gcatgatgac aacgattgct gccgctccaa
    35821 ctaaatacca gacaacttgc atccctacgc ctttcaagac tgctggattg ttcggatcat
    35881 ggctaagtgc tacatataat gagagcagac caatcaaaca taacagaaag actggtaaaa
    35941 tcacgccata atcaatacga ttatcgttcg aagcttttaa ttttttttcc atgtttcatc
    36001 ccttttctta aaaaccatac tgctgattat tatagcggtc cagttagata atggaaagtc
    36061 tttccataga catttgggaa aaattaactt tccgtttgtg cagttgcttg agcaaatgca
    36121 gtacaaaagc ctactgctta tctttagtgt atcatagaac tttttttgat acatgcaatt
    36181 atctaccagc tgagattctc ctcgctgtga gaagtttctg tgctttcatt gtatcgaagg
    36241 atctcttcgg caatctctag cagctgatca gaaaccagat tggttcgttg gatgaaataa
    36301 aaatatcgat ggaaattcaa cggagtcatt ggcacatttt ctggaacaga gcgcttagac
    36361 aaaatcgagc gaccgattcc ttccttcagc aacgcaacaa ttacatcgtt acttttcacg
    36421 atcatcttct tatcttggat attcatctct tcaaaataac gctgcgtgta atgaaaaaca
    36481 ccagagtttg cttctcttac aagccacaat ttgctttttg ggtccccagc gatgactagc
    36541 tggtcttcca tcaaagagta tctttgtacg ccggaagtct ctaatggctt ttcgataaaa
    36601 ccaaaatcgg attcatgttt cgctacttgt tctaatgatt catgagaatt cgtgatttcg
    36661 atctcaaaat gcactttagg aaaccttttg atcagatgtt tcatcaactg aggcaaaaga
    36721 tagacagcaa aggtgtggga agcaacgatc cgacatactt cttcttcatt ttgttcattg
    36781 agcaattttt gctgagtttc ttcccattct tctaacaaaa ccagtgtccg ttcatataat
    36841 aagtcggctt gcttagttgg aagcatctct tttcttccgt tacgttgaaa aagatcgata
    36901 ttcaattccc gctccaactg tttgatttga ttcgagactg ctggttgaga taaaaacagt
    36961 acttctgctg ctctggaaaa atttcttgtt tcatatactg ctcgaaaagt cgttaataac
    37021 ttaaacatgg caccacttcc ataacttttt atgataatta ctataaaaac tatttgattt
    37081 aaatatacaa aaaaccatct ataatagaaa tgtacaacaa aacagttgct gatccaacta
    37141 gtaacttaga tgaagacaat cagctgtctg cttgctcgta atcatacatt cctattcatt
    37201 ttacaatgta ttcgttcatc ttggtactaa aatctattaa ataaaaagga gaatattata
    37261 tatgaagaac tttttgaaaa ttattccgat cccgatctgc gggttgatcc ttgggttagc
    37321 ttcccttgga aatctgttta aagactatca ccatgttgct ttaggcaatc taactggcgg
    37381 tatctctatg attcttatga tattcatttt tgttaaattg tttatcttat tcgaacacac
    37441 gaaacaaacg ttgcatgatc caatcatcgc ctccgtttca ccaactttta cgatgtcact
    37501 catggttatt tgtacttatt ttgtttcata tgaaagtatt gcaccaattg tcaaattcat
    37561 ttggctgtgc gctgttatct tccaagtgat ccttgtcttt tatttcaatt atcaccatgt
    37621 tatcaaagct gatctttcaa ttgaagcaat ttatccaagc tggtttatca tttacgttgg
    37681 atttggggtc atcactgtaa ctgccgggaa cttcttccca cttattggaa aaattttctt
    37741 ttggatttca ttgatctgct atgcgttctt attgccgatc atcatcaaac gtgtcttttt
    37801 cgtaagaaat atggctcatc cgacacgtcc gctgattacg atcgttgcag cacctggttc
    37861 tctttgccta acaggttatc ttaaaaactt tgctgaacct aatttttatc ttgtcgtagc
    37921 attgttcgct ttatctcaag tattgtattt cgttgtgctg tctatgcttc cacgtttgtt
    37981 caagcttcgt ttttatccaa gctatgcagc ctttacattc ccgcttgtta tctctgcaac
    38041 agctatattt actactgttc attacttcaa cagtttaggt atctatagta gcgtattgga
    38101 tttcttaaaa gttgcggaat gtctgtttgc aagtgtagtt gtcttctacg ttcttgctca
    38161 ttacgtacgt ttcttaatta aagaacatag caaacatgga aaatttgttt ctaaaaaaat
    38221 cgcttaataa tcgattcaat aggttgtgaa aaagctgttc tgcatcaagt aataagaacg
    38281 gccaaacaaa aacagctgtt catgtttttg tactggttgg gcttattacc gcagatgcaa
    38341 gcttttgaac accgtttacc aagaggtcgt aaaagaagtg gtcagcttca agaaataaga
    38401 aggaatttac gaaaattgct tctcaaattt ttgtgaaatt tcggcttatt tccgtagaag
    38461 ctacttctgg aacaccgttt attcgaaaca agaggtcgta caagactttt gtcacgacct
    38521 cttgttcttt tgtcaaaata ctggtttagt gctactatgt tcgagtatgc ttttagtatt
    38581 tattgacgaa aggaaccgat caaatgaaat cattgtcaca tccaataaaa tctgtaaagg
    38641 attcagcggt ccgcgaaatc ttacccggtt tactgctttc ttttgccatc gctgccttca
    38701 gcaggcttct tgctatttat ctgccacagt taggtggagc gactattgct attttattgg
    38761 gtattttatt aggaaatact ttttttaaac agcctgttct agcaatcggc acaaaatttg
    38821 ctgaaagcaa actattagaa ttctctgttt ttttactagg tgcaactgtc acagctcaaa
    38881 cgattgctca aattggtgta aaaggaattg tttttgtgtt actgcaaatg tcagtcacta
    38941 tcatcggtgc ttacttgatt ggtaaaaaac tgcaattcag cgatacttct tctttgatga
    39001 tggctggagg aaacgctgtt tgtggttctt ctgctattgc ttcaatcgcc ccttccatcc
    39061 atgcgaaaga ggaagaaaaa ggacagatca tcacactagt caatctactg ggtactgtga
    39121 tgatgttgac tctccctttt cttggattac agttgtttgg tggaaatctc attgaaaaaa
    39181 gtgcactttt gggtggtaca ctccaatctg ttggtcaagt agtcgctggg gcaagcttac
    39241 ttgacaattc tgttgtcgaa ttcgccatgc tatttaagat tctacgtatt atgatgctcg
    39301 ttgttgttgt ctatctgttt gaaaaattca tgcacaagaa acaaccagct ctgtttgaaa
    39361 cgccaactga tacgcagaaa aaacgaaaat taccgcttcc ttggtatgta ttagggtttg
    39421 tgatcttttg tttggtcaac agcttgtttt ctttacctgt agttattgac caatcggcac
    39481 attttatcag cagctggttt gagatcactg ctttagcggc aattggtctg cgtttagact
    39541 ttgcaaaatt catgaaagaa ggtacacgct tcttatctta tggattagct gtcgggcttc
    39601 tccaaacagt gatggcttta ctatttattt ggctgatcaa agtttagaat gaacatgaaa
    39661 aaacagttgt gattctcgca tggaacaatg tccgaatcac aactgttttt aattttgcag
    39721 atatccttct aacaacaaca attggcgttt gatttcaacc ccatctattg cgtttcccat
    39781 atatcctgtc agttttccat tttgcccgat cactcgatga caaggaataa cgattggcaa
    39841 tggattggtt cgatttgcct gcccaatcgc tcgcacagct ttcggactat caacagcaac
    39901 ggctacttct ttatacgttc ggatttctcc ataaggaatg gtcgacaaag ctttccagac
    39961 attttgctga aaaggcgtac ctctctttat agataaagga acatcaaatt cttttctttt
    40021 tcccgcaaaa tattcttcaa actgttcttg tgtgcgcgtt aaaattcgct gattcgctga
    40081 ttcgctttct gaaattggct gaaaagatac agcagtcaat ccggattcat ctgcatctaa
    40141 ccataaaaag ccgataggtg tgtgtatttt cattttgttt gctcctagtc aatagactgg
    40201 aacttcctcc tttttctcta tccaaaacta cttgccaact aataaaaatt gttcttaaaa
    40261 gtttgataaa ccgaggaaac atggtaaact aaatacgtta gtttacaaaa agaatacctg
    40321 ttcttttacg taaaatcaaa ttttaaaggt gttatttaag gtttattaaa ttttgaatgt
    40381 aaaccatata taaacatacg attgaaagga tagaaacgat gaaagtatca attgttgtcc
    40441 catgttttaa tgaagaaaaa actgttcctc ttttttttga tgaggttgaa aaattcaaag
    40501 gtgcccatga gttcgaatat ttgtttattg acgacggatc aaaagacggt acgttagcag
    40561 caatcaagaa gctagcctca gcttatcctt atgtccgctt tgtctcattt tccagaaatt
    40621 ttgggaaaga agcggctctg tacgctggat tgcaagcttc tacaggagat ttagtgaccg
    40681 tgatggatgt tgatctgcaa gatccgcccg aactgcttcc tgagatgatc aaccggatca
    40741 ctacttctga tatcgattgt gtcggcaccc ggcgttcgac tcgtgaaggc gagcctgcga
    40801 tacgcagttt ctttgcgaaa aaattctacc agttgatcaa taaaatcagc gatacagaaa
    40861 tggtcgatgg cgctcgtgat ttccgcttga tgactcgtca aatggtggat gccgtcctag
    40921 aattaacaga atacaaccga ttttcaaaag gattatttag ctgggtcgga tttaaaacag
    40981 aatatatttc ttatgaaaac cgcgaacgtg tggctggcga aacatcttgg tccttctgga
    41041 aattattcaa ctactcgatt gatggtatcg tgaacttctc ggatgcaccg ttaacgattg
    41101 cttcatttat cggcgctttg tcttgtgtcg gttctggtat tgcaattttg ttcattattt
    41161 tgcgggcatt gttgtttggt gatcctacat caggatggcc ttccatggtc tcgatcttcc
    41221 tgttcattgg tggaatccaa ttgttatgtc ttggaatcat cgggaaatat attgggaaaa
    41281 tcttcttaga aacgaaacag cgtcctgttt atatcataag agaaacagaa aaagtgaagc
    41341 caaatgaatt gaagcctcac caataatata cgtcaaatga agtaaacatt tttttaaatg
    41401 aaaaaggact gtgacaaaag tcttgtcaca gtcctttttt ccgaataaat ggtgttccag
    41461 aagtagcttc ttcggaaata agccgaaatt tcacaaaaat ttgagaagca attttcgtaa
    41521 attccttctt atttcttgaa gctgaccact tctatcacaa cctctttcat atcttattac
    41581 ttcttcattg ctgcttttag tgctgctgct aatgggcttt cttctggttc ttctgcttgt
    41641 gcatattttt tcagcaagcg tcgttcttca tgtttggtca ttttcttctt ctgctctttt
    41701 ttatcaagca atttttctgt cgttccatcg tatttacaac ggaaataagc accgttttta
    41761 ccttcgatga tttccatttt ccggtgacat tgcgggcatc gatgattaga gacttttgga
    41821 tcttttcttc tgcggtagtt gcaatctgaa ttggtgcaga catagatttt gccgtcacgt
    41881 gtgtttttct cgcgcagatt ggccccacat tctgggcatt tcttttgggt aatcgagaaa
    41941 tcttgatatt cttgtttgct tgatttgatc tcattcacca agcgttttgt ttctttttcg
    42001 attccattca agaaggttcc tgcttgtttc tttcctgcag caatagcttc aaggtctttt
    42061 tcccagcttt ctgtcaaatc tggtgttact aaagagggat ttaccaatac taataattgc
    42121 ttacctttag gagatacttg cagtccttga ggggtacgtt ccatcagttc agatttgatt
    42181 agtttctcga taatctctgc acgcgtagct ggggttccca gactgtattt ttccatttga
    42241 ccaagcaagc ttgcttctga caatggttta ggcggtgcag atagttcttt tttgatggcg
    42301 aaatcgggat tgattctcat tcctttttcc catttgactg tttccgtctc agtttcagtt
    42361 tcgcctttcc atcctgcttg gacgacacga ttttgccgaa aaatgaatcg ttctttacca
    42421 aattcaaccg taacttttgt ttggctgact ttatggggtt gagcaaacag tcctaaaaaa
    42481 cgagagacaa tcatttgata gatttttcgc tcttcattac ttaatttttc ataacgtgct
    42541 ctgttttcag ttggcaaaag tgcatggtga tcggtcactt tactgtcttg gaatactttt
    42601 gtctgttgga cgatggctcc gtttttcaaa tactgcttga cctcaggagc aaagtcgctg
    42661 actgcttgca atcgttcttt catcgtactt ttcatgtcat ttgtcagata tttgctgtct
    42721 gtacgcggat aagtaacgat cttatgggtc tcatacaaac tttgtacaag acttaatgtt
    42781 ttctttgcag aatagccata gcgttgattg gcttctcttt ggatctctgt taaatcataa
    42841 ggcaatggcg cagattccgt ttttaatttt tcttggactt ctgtgacagt tcctttgctt
    42901 gtactgatca attgaacaag tttttgtgct tcttcttgtg tttttaaagc aaattgattt
    42961 ttttgaagca ttttggcttg ttcttttcca gcttgcaacg tgatcgtgaa atacgtttgt
    43021 ggacggaact gctcgatttt cttttcttgg tctctcacta atgctagtgt cggtgtctgc
    43081 acacggcctg ctgataaatt atccgcgtac ttcacagtta aggctctggt cacattcaat
    43141 cctaccagcc agtccgcttt tgcccgggca agagcagatt catacaatgc atcatattct
    43201 ttcgcaggtc ttagttgctt gaatccagtt ttgattgctt tatctgtttg agaagagatc
    43261 cataaccgct tcactggttt attgaaatgc acatactcta agatccagcg agcaacaagt
    43321 tccccttctc ttccggcatc tgtcgcaatg actgcttctg agacatcttt tcgctgagcc
    43381 agctgcttga ttgcttttaa ttgatgtcct gttttaggaa gtggtttgat tcctagtttt
    43441 ttagggatca ttggcaacgt gtccatttgc cagctctgcc attccttatt cagatcttcc
    43501 ggcattttca atcctaataa atgaccaagg gcccaagtaa cgatcacctt gggtccttca
    43561 taataatttt tgtgcttttg attagcacca agcaccttgc ttaggtcttt cgcaacgctt
    43621 ggtttttccg ctagaattag ttgtttcata aaattccttt ctgctttcta ctgtgatggg
    43681 ctgatgattt ttcaacaacg caagtccctt gtattgctgt aaatcatcgt cacactcttc
    43741 acaccagcgc tcatctccgt cattccaaaa ggcgctgaga aagttacttt ttgcattgat
    43801 atattcataa ttttgatgga tttcgttcca ttgtttttcg tacgcttgtc gtgcttcttc
    43861 gaaagactcg aatgtttctt cttcttcaat atcttcttcc cagtcttcaa aaaaccacca
    43921 aggctcattg tccccgaaca tggtaattac ttgatacata ctcgtgctcc ttctttcagc
    43981 ttttctagac tcatcttagt cacttttcaa gaaagttgca agaattttct cttataaaag
    44041 ggtcatttaa tgaacatctt aaaattgtta caaatgaatc tgattgttta aggcaaagta
    44101 gcgataaagt tattgatcat ccaaaaatag ctgtcttctg gatcgattgt tggttctttt
    44161 gtaaagtatc ctaaaaaacg taaggaaaga taaccgtgga tcatactacg aagttccctg
    44221 cttcgatgaa ctttttcttc tttcgttaat tgaaaagcct caaatatctg caaaatgatc
    44281 tgattcgttt catggattcc atctaataaa acagcttcat tggtatgcgg tacactgatc
    44341 agtaactcat acactgcttg atttgaaaaa gcaaaggatc gataagtttc tgcatagatc
    44401 tgcagtgctt cctgaccact ttttcccaca agagcccgtc gcagctggtc attaagttcc
    44461 tgcagaagtt tcgctgttag cgctgttttg acatcacgaa tatttttgaa atggttatac
    44521 agcgagggag ccttgatatc caagcgtttg gctaaatgct gaaaggttat ttgctgaaca
    44581 tccatctctt ctgctagttc tcgaaagcag tcgatgattt tctcttgaga cagatttctt
    44641 tttttcattt ccatgtttcc tctcataaaa taaatccttc actctttcag tttaccacga
    44701 aaaagaaaga gaaaaaagag actttcattg ataaactaca tattgtagtt tataataaag
    44761 agctgtagat gaaaattttc agaaagaagg agtctaattg gctgcaagaa taaaggaaaa
    44821 attatttagg aaaagagaaa cttgggaaca aaacttgttt gtcttatggt ttggaacatt
    44881 tatggctggt atcggattta gtttagtcat gccttttatg tcactttaca tagatacgtt
    44941 aggtaattat agtacgtcac aattgaactt ttggagcgga ttgacttttt catctacttt
    45001 cttggtgact acgcttatct ctccttggtg gggaaaatta gccgaccaaa aaggaagaaa
    45061 attgatgctg ttgcgtgctt cattaggaat ggcaatcgtc atttctttga tgggttgcgt
    45121 gactagtgtg tatcaattag tcgcattgcg tctgcttcaa gggatttttt ctggttatat
    45181 cagtaatgcc actgcccttg tcgcaactgg gacgccaaaa gaaaaaagtg gtcaagttct
    45241 tggaacctta gcaactggtt ctgttacagg aacattactt ggaccgcttc ttggcgggat
    45301 ctctgcttca gcgtttggct atcgccctac ctttttcatt acagggatca tcttattttt
    45361 cgtcttcttg ttgagtctgt ttttcgtcca tgaaaaattt gtcccagtga aaaaagaaaa
    45421 catggtttct gccaaacaga ttttcaaaga cttgaaatat ccacacgtcg tcatcggtat
    45481 gttcgtcaca acgatgatca tccaagcatc caacaattcc attagtccaa tcatcagtct
    45541 gtacattcgc caattgctgc atggacatgg gaatgttacg ttgatcagcg gaatcattgc
    45601 ttcgatacct gggattgcca ctttgatagc cgctccaaga tttggtcgct taggtgacaa
    45661 gattgggagt gaaagaatac ttgcgattgg tttgggtttt gcgattctgg tttatatccc
    45721 aatggcattc gtcacgaatg tttggcaatt agctgcctta cgttttttga ttggtatctc
    45781 tgatgcttgt ctgctccctg ctgtccaagc attgatcaca aaatattcgc ctcatcaagc
    45841 tgctggacgg atcttcagtt ataaccaatc tttccaagca actggtaacg tagtagggcc
    45901 tatgatcggc tccagtgttt ccagtgcatt tggttatcgt ggcgtctttc tttcgacttc
    45961 tcttcttgtt ttggtcaact tcttgcttgt acgacacaat acacaagaga tccatcagca
    46021 agaaactgca gaagaaaaag cttcaggagt ctccatagct tcagggcact ctccttctca
    46081 tagacaataa gcgtaaatga aaaacactgc ttgaacagtt gtcacagact gtccttgcag
    46141 tgtttttgtt taggcctgtt ttttcaagaa ctcagataag aggaataatc ccttttccaa
    46201 ggtttctttt ttacaacagt aacctagtcg ggcatgcttc ggtaaatcaa aggcacttcc
    46261 tggtactaat agtactcctg tttcttctaa taaattgata caaaatgtct ggtcatcttc
    46321 ttcgatggct aatttaatga aagaagtaga gacgtaattg ggagcgacaa gttcaacttt
    46381 cggttcattg gctacccatt gttttaaaat cacaaggttc tctgtaatga tctttttgtt
    46441 tcgcgccaat attttttctt tattcttcaa tgcatgtaca gcaagatcat ctgacaggac
    46501 tccgccgcaa atcatcgtgt agtctcgata ctttcgaaaa acttctgcca actcaggtcc
    46561 agtagctgtc cagccaatac gaatacctgg aatggagtag gttttggata gggaattggt
    46621 tgctatacct ttttcataga catctacgat cgacaagaat tcacctttat ccgttaaagg
    46681 cgcatatact tcatctatca atacatatgc atctactgta cgagcaattt ctgcgatttt
    46741 ttctaaagtt ttccgatcta gcaatgtgcc tgtaggattg tttgcactat tcaaacagat
    46801 gatttttgtt tcaggtttga ctaaggcttc tagctgttct aaatcaaact gccaatcttc
    46861 ttcttccttc aaatgaacaa agtcaacagc ggcacctaaa gatttgggga tgtcatataa
    46921 ttgctgataa gtaggaagca tcgaaacaac atggtctcct gcttccacta acgcgtatag
    46981 agctaaaaga ttagcaccag tcgctccatt cgtttgtaag atgttttccg gatcgacggt
    47041 ttgataaaga gaagcgactt cttgtttgaa aacatctgat ccttcgatcc agccatagtc
    47101 caatggttcg tttttgcgtt tttcgaaaaa tttacttacg ctagtcccat ctaagccaac
    47161 gagttcgtct aatgtcaatg cttcgatcga gctttgtgca atatcatata ccgctttctt
    47221 ttcccattta tttagccatt cttctacacc gaaatttgcg attttcatgt ttctttcccc
    47281 cttatatctt gatccagcct acagcaagca acccgattga aagcagtgcg gccacacaaa
    47341 tcagcccaat cattactttt tcttttcccg taatttgatg tttggtttca cgacaagcga
    47401 tccagtagaa gcaaaaacca ggaagatagg caatactaca taaaaggaca taagaaaatc
    47461 ctgctaaaat gatgcccatc aattcaaaaa ctacagcaat cccaccgatc actacttgtt
    47521 ttttgattcc ttcttttaaa gaaaactgga cttgatagat cccgacaagt agataacaaa
    47581 tcaaaattgc cgctgtacat aaagaatagg caaattgata ggcataatca gtaactaaga
    47641 aagtcaataa gaatagatta gtcaagattg cagtaacaac taacgaataa gttggggcat
    47701 tttttttatt cgtttttccc caacctttcg gcaacagacc gtctcgagcc atcaacatcg
    47761 ttgtttctgc tgggagcatc gtccaagaca accaagaacc aatgatcgaa ataatcaagc
    47821 cgatattgat cagcgctgct ccccaatttc ccacgattcc ttttaaaata tttgccatag
    47881 caggttgtga aatagttgct aactcttctt gagataagac gccgtatggc aagatcgaag
    47941 caaggatata gataaacaat aaacaaagca gaccaatgat cgatgcttgc tgggcttctg
    48001 aacgtttctt cgcgcggttg gctaaaacac ttgcgccttc gatccctaca aagacccaca
    48061 tcataaccat caaacaacct ttaatctgca accagatcgt tccttgctgc cctgttccat
    48121 tcactagatt atcagatacg ttaccccaaa aatcagcagt gaatatattc actttaaatg
    48181 cgataaatac aaatattaaa aataggaata atggcactaa tttacagatc gtcacgattg
    48241 tattgatgac gctcgctcct tcaactccat tgtttactaa taaagtcaga ccccaaataa
    48301 aaatacttgc aaataaaata gaaggaacat tttgtccacc tttgaatatc gggaaaaatt
    48361 ctcccatggc gctcatcagc atcgttgcaa aagcaacatt tcccagccac gcagacaacc
    48421 agtaacccca accactgatg aagccaccta atttaccaaa tgaagcttcc gcgtaaccga
    48481 aaataccacc atctagatct ggacgctttt ctcctaaatg attcagcgat aataccaaag
    48541 ctaaaatacc aatcccaacg attatccatg aaaggatcgc tggccctgga gctgcagaac
    48601 tagccagatc acttgtgatc ccaaacacac cgcttccgat tgacgaactg acaaccagag
    48661 caaccagtcc ccatttgcta atacccgtcg atttcttttc catttccatc accctcactt
    48721 ataaaattga acaaatcact tgcaaaagat tcccttctat tttgcaactg ctcttgctta
    48781 acaaaaagca actttattca tattattgga tattatgaac tttttacaca agtatttcaa
    48841 gtataaaatg aataaaaatt aattttattg caaaaaaaca gctatgctat ccaaaagaaa
    48901 aggtgtttct tttgttagcc atagctgttt tgattcattt aatatcgctt aaacgtattg
    48961 taaaactttt gtttcttgat atgcgtggtc gatcaaacca ccacccagac attccattcc
    49021 atcataaaat acaactgctt gtccaggagt gattgcacgt acaggttcgt cgaatacgac
    49081 ttctgcacga ttatcatcca ataagcgaac tgtcacagga acgtcttgct gacgataacg
    49141 gaatttcgct gtacacttga attcttttgg cattggttca ttcgtcgtaa agtggatttc
    49201 acttgcatcc aagcttgtgg catacaatgc aggatgatgg aacccttgcc ccacatataa
    49261 tgtgtttgtc gctagatctt ttcctacaac aaaccagggt tcttgcgaat ctcctccgcc
    49321 accgatccct agtccttgac gttgaccaat cgtataatac atcaagccag catgttgtcc
    49381 tttgacttca ccatcaagag tgaccatatt tccttttttt gctggcagat agttgctcaa
    49441 aaattgtttg aagttctttt caccaataaa gcagattccc gttgaatctt ttttcttagc
    49501 agtcgcaagg cctgcgcgtt cagcaattgc ccgtacttct gatttttcca tgccgcctag
    49561 agggaacatc gtttttgaaa gctgttcttg tgataattgg ctaaggaagt aagtttgatc
    49621 tttattattg tctactccac gaagcatgtg gaccacgccg ttttcatcgc gagtgacttg
    49681 cgcataatgt ccagtagcta cataatcggc gccaagatcc attgcataat ccaagaatgc
    49741 tttgaatttg atttctttgt tgcacatcac gtctgggtta ggtgtacgtc ctgcgcggta
    49801 ttcggctagg aaatattcaa atacacgatc ccaatattct ttttcaaaat tcacagagta
    49861 ataaggaatc ccgatttgag cagctacttt cgctacatcc ttataatctt ccgtggccgt
    49921 gcatacaccg ttttcgtccg tgtcatccca atttttcatg aatattccga tcacgtcgta
    49981 tccttgttcc tttaacaaaa gtgctgttac agatgagtcg acaccgccgc tcatccctac
    50041 gacaacgcgt gttttgctgt tgtctgtcat gatatcacca tcatttcaat tagattctga
    50101 aacatctacg agttgaaggt cgcaactttt cagtatttta cattatacgt catatttctg
    50161 aaaatttcat cccttaatta tcaagtcgta aaaatactgt tctactggac ctattcagta
    50221 cacaaacatg atagtcaacc aaaaaatcac tcatcttttg agcattcgat ataaaaaatt
    50281 ggcatactca taaaaagggc cagcctttcg gcaataagga ataattttat aaattgtgaa
    50341 aaactatttt tcaaaattgc ttcttatcgc ttaaagctgc acgtctcatt tacaaccttt
    50401 tctttttaga tgttatgagt tgctcagata agtgattttg tttactctaa gaaaaaaggg
    50461 aggcaaaaga tacatgaatt actttatcag tgatatgcac tttttccatg aacacttatt
    50521 aggaaaaaac gactttgctc cgcggctctt tgcaaatgtg gatgaaatga accaacagtt
    50581 gatcactagc tggaatgcag taataaaaga aaccgaccat gtttatcatc taggcgacct
    50641 tgctatgcat ccgcaatatg aaaaagcaaa tgcagaaatt ttggaactgg tcactcaact
    50701 gcaaggaaca atccacttga tcaaagggaa ccatgacagt cgcgcttttt tccgttattt
    50761 agaaaaaaat gatcctaggc ttactgacgg aagtcccaaa ttttattttt atgatgtagg
    50821 tgccatcgtt aaattcgacc atcaacaata ttacttgact cattatccga tgttgctcgg
    50881 gcctaacgac actatccgca atcttcatgg acatatccat cattacagcg tacctatcga
    50941 gaacgatgtc aatgtaggcg tagacgcacc ggaaagagaa ctcttaaagg aaaaactacc
    51001 atttggcact ccgttatctg agcaacaaat caaagaaatc tatgaagcaa agaggaagta
    51061 cgataggtcg tgaaaaaact gccctatatc aagtattaaa caaataaaga taattactca
    51121 tatttttcat ttgagtaggc ttattgccac aggaacatta ggatcagaaa tggagttgta
    51181 acaagacttc tgtcacaact ccattccata ctattcgtct ttttgctcat ggtgttcttt
    51241 taccagtttt ttctgtaatt ctttatcata atttcgggca gctgacgtta aaaataaaac
    51301 gattccgcat aataaaatcc cgattccgga aaacaagaac attttttcta cccctaaacg
    51361 atcagctaat ggtcctgcaa ataataatcc aattggacct gccaggttca tcaaagagtt
    51421 gaagttccct aagacacgac ctaaaacatt cgattcataa ctctgctgga tcattgccat
    51481 cagcagtgta ttgaaatatg gcgttgcaca acctgctcct gcattcaaga taagaaagta
    51541 caagaaccct tgactatcgt ttggaaccaa tccgcttgca ccgatcgtca ggcccataat
    51601 gatgtaggct ataataatag gtttcattcg gtctttccat gttcctataa aactgatcag
    51661 tgcaccgcct aagagcattc cgactgcgta gactacttcc actgctcccg cctgtccaac
    51721 ggaaccacca aagtaatcta gcgtcatcaa tggatacaga ctgattgctg gcatgaacaa
    51781 cagcatcaca aatgcaccat tgatcgttat gtaccataac cctttattat ccatcaattg
    51841 ctgcagccca aattttgcat ctttaaaaat agtaagcgga acttccaata tttcaggaga
    51901 aacttttggg atcttcacaa aaatcaataa gccgacacca aaaactgccc ccaatacatc
    51961 taataaaata aggtaattga caggaacgac tgaaaacaaa gccgcaccta gagctggcgc
    52021 aatgatgaaa ttcgctgatt ggaccattcc taactgtcca ttcgtccttg ttatgtgaga
    52081 agatggaacg attgtcggca taatcgactg gatcgttggc atttggaatg tttgtgcgac
    52141 cgaacgcata aacaaagaca caaaaactag ccaaatcggg aaggattctg aaatcgttcc
    52201 gactactgct aaaataagcg cgaaaatcgc tacaataata tccgtgacaa tcaaaagagc
    52261 ttttttatcc cagcgatcca ctagcggtcc tacaaatggg cttagtaaaa ccatgggaat
    52321 cattcctagt aaagtagcaa aactcaaaat tgtcgccgaa ccggtttctc ttgtcaaata
    52381 ccagatgatc gcatattgga cgaccatact agtgattcct gacaaaaact gtcccgataa
    52441 aaagaacaaa taatttctct tccaattcgt taaaacgacc gactgttcat tttccataaa
    52501 catccctctt ttctttttca ttttgtatag cgtttgcaca acaatcatta tacgggattc
    52561 ttttttcaaa aaataccttt ttccctaaat aacaatcgtt tcaatttaaa tttctttact
    52621 tagaaacaat aaatcagcaa aatattaaaa ataacaacat gtgttaaatt taaaaataaa
    52681 aaagacaact aatttgcgtc gtccttacaa agttagtcat ctaacaatag gccgtttcaa
    52741 aactagttgt ctttttatat ccacagatca ttcgactttt tcgaataacc cacggctaat
    52801 catcccatcc atcagaaaat aaaatttatc ttggctcatt ttctgttttg gatctttgaa
    52861 aatattgact gctttcaatc catttgctgt agtgatcgac attttcaatg tttgaatatc
    52921 ttttgataca gtgattttta atttgaatcc ttctttgctt tgcggcgtgg catctaatgg
    52981 tcggatcaat tgataattgc ctccgtttgt ttctgtaaat ccattatcgc gcaatgtata
    53041 tctttttgca tcaggatgca aacgatagct aattggtgcg cccagtaccg ttgctgttgt
    53101 ttcaaatgcc atgattttca cctcgataaa attagtttct ctttattata aaagtttatc
    53161 ctgattttta ctaggttttt cagttaagtt ccctaaaaaa tgaaggcgtt ctctcagaca
    53221 tctgttcata taagaatgac ttcactagtt attttttgac agcacgaact aattgatcaa
    53281 ggaaatactg gatgtcgtct tcggtatttc ccaaaccaaa gctgatacgg atggattctt
    53341 ttagtatcgg tgtatcttct ccatacattg cttctaatac gtgtgaaggc tcgatatttc
    53401 ctgctgtaca agctgaacca gtagaaatag cgaccccatt aagatcaagc ttcatcagta
    53461 gcaaatcatt tgcttcgcca attaagcgaa gattcaacac atgagggagt ttattcgtta
    53521 aatcaccatt tacttgataa gggatttcgt ttgcttctaa tgtatcaaga atcaattgct
    53581 ggaatccttt atatttgttg ttacgtgctt cacgttcttc aggtgacagc agttcaactg
    53641 cttttgccat accccagatc cctgctaaat tttctgtacc tgcacgccgc ttttcttcct
    53701 gctccccgcc taaaagcaat gcagggatat ttactccgtc tcgtttatat aagaaaccga
    53761 cgccttttgg cccattgatt ttatgagcag agatacttaa taaatcgatt cctaattctt
    53821 ctggatggat cgtttggttt ccgtacgctt gtaccgcatc tgtatggaaa taagctggat
    53881 gatccgctaa aagttcaccg atttctttga ttggcatcaa atttccgatt tcattgttcc
    53941 cgtacatcac agagaccaag atcgtatctt ctcgtaacgc ttttttgacc tcttcgatcg
    54001 acagattccc tttttcatct acaggcagat atgtaacgtc aaaccccttt gtctctaaat
    54061 atttcatggt attaagaaca gcaggatgtt cgatagctgt agtgattaga tgtctgcctt
    54121 ctttttgacg cgagaacgct gtttctaaga tagctgtatt atccccttct gttcccccac
    54181 tgttaaagat gatctcgtga ggttttgctt gcagactgtc tgcaatgatt tgtcttgctg
    54241 tttccaattt ttcatgcgcg tggcgaccaa atccatgtat gcttgaagga tttccaaacg
    54301 tgtcttgcat gattgccgtc atcgcttcaa ttacttgtgg atgcatgggg gtagttgccg
    54361 catgatccag ataaatagtt ttcacttcat tcatcccttc caaattattg ctaggcacat
    54421 tctagcataa aatagcgaac aaaccaaaga agagctcatt tttgtctaga ggacgtttca
    54481 tgggcataga aaaaaggagc tgtgacaaaa gtcttgtcgc agctccttga agctgctcac
    54541 ttctgtcaca acttctttcc ctcttttttt tgtttattcg aattcttttt cttccagacg
    54601 gaataacgga ctcatcggtg tattttcatg gatgcgtttg accgcttcac ccattaattc
    54661 tgaacatgta acgattgtta agttttctgg atgacgattt tcttctgtga aaacagaatc
    54721 agtgatacaa atatctttga ttggtgcatt gtctaaaata cttttcgcat gatcggacaa
    54781 taatccatgt gacgcacagg catatacttc ttttgcgccg ttttctttta atacatttgc
    54841 tgctcgtgca agcgttgctc ctgtgttcaa gatatcatct accatgatac atgtctttcc
    54901 ttgaacatca ccgatcacat aaccaccctc agttgaagca tcatctgcat gatctacgat
    54961 ggctaatgtg ctgttcaaat attctgaaag actacgtgca cgctgaacac cgctgttttt
    55021 tggcgaaaca actacgatgt catctcccgt cagacctaat tgacggtaat aatgagcaaa
    55081 caacggcatc gtaaataaat tatctacagg aatatcaaag aatccttgta cttgaaccgt
    55141 gtgcagatct aaagtcagta ctcgagttgc ccctgcttct tcgatcaagt tagcgatcaa
    55201 tttcgcagtg atcggttcat gaggtttcgc cgtgcggtct tgcctagcat acccatagta
    55261 aggcaatacg acattgatcg ttttcgcact tgctcgcttc attgcatcga tcatgatcag
    55321 tagttccata tagtaatcat tgacaggtgc attcgttgat tgaacgatat acacatgatc
    55381 ccctcgaata ctttcttcga tattgatgga aatctcgcca tcactaaatt gcttcacgac
    55441 gcttttacct aattctgttc cgaacacttt cgcgattttt tcagctaatg gacggttgcc
    55501 attcaaacta aaaatcttca acgtgtcatc ctgatactta ttactcatgt agtcctcccc
    55561 aaaacttctc tattcttcga tagtttaaca tatttttcca agattttctg ttaatttcag
    55621 caaattctta aggaagtgaa actgttccgt tactccaact ggcaggaatg actttatgat
    55681 aatcgcccca gttgtcgtgt actttgtaat aacgttctcc tgtttcagtt tcaaaataag
    55741 cgtacgctgt cacccaatga ttgccatatg tactgccaag tactttcaaa ataccaatca
    55801 tcacaggttt gccttcacgt atacgttttg tagctcgctg ccatgaacct agaagagttg
    55861 ctcgtgcacg ctcatgattg ccattcttct ttaaaaaact agaaatccct gtactaacct
    55921 gaaaaggaat cgtaggaagt cctagtggtt ggatctggct acgcaatgcc ttcgtcaaaa
    55981 ccaacgaatc agccgtattt ttcttgcgaa tctcatttgg aagcatccac cccttacgat
    56041 agtcttgata ataggcaagg agaactgctg ccgcgtaagt accacaaaga tagcctgagg
    56101 gggtagccca tttcttatac ctcaaaaaac gttcttctgg caatcccacc cagcaatttg
    56161 cgagttcctt tcctgacctt ttttcttcga tcaaaacggg aatatcttct tttctgttga
    56221 tccatctaga taactcgatt ggctcttcat tgatcagctt ccatttttta caagaaagac
    56281 cctcttgata agtatatttt gctggagaat attctaccgg atgtcctgat tgatcgataa
    56341 tcacataact ttgatcttca aaaaccagag ctaaaaaaag caatttactt tttcttgact
    56401 gcagctgctg agtgctggct aattttttaa tttttttatc tactttgaaa tataaaggtt
    56461 tatccactac ttgattcagt tgggatcgcc tccttttttt cattataagt gaaggattga
    56521 aaaaaacaaa tcagtttgat tgttcgaatt ttcaattttt tatgttctat ttgttaattc
    56581 cttcattttg taagataatg ggcacacgaa acaaaaaagg agcgatcgat gaatgaacaa
    56641 agaacgattg aaacaagatt tctatgaagc agtcaatgaa gaatggcaaa aaacagcaaa
    56701 aatccctgca gataaaccag ctacaggcgg tttccaagat ttagttgacg ggatcgacca
    56761 acttttgatg ggagaaacag acgatctgct tgcccatcca gaaaaagtgt cttcagaaaa
    56821 aatgaaacat ttccttgcat attatcaact ggcaaacgat tatgaccgaa gaaatgagtt
    56881 gcatgctcaa ccgcttcaac ctataatcga aaaagttgaa tcattgcagt ctttcgacga
    56941 attgaataag caatttccag aatggctgtt ggatacatta ccattgccat ttaatctgga
    57001 tgtagatgca gatatgaaga atgcgcaaac gaacgccttc tttgcttatc cgccttcttt
    57061 attccttcca gataagacgt attatgcatc agaccatccc aacggtgcac aactaatagg
    57121 cgttttcttt gatatggctg ttcagttatt agagcttgcc ggcaaagaaa aaagtcaggc
    57181 agaagcaatc acggaacaag cagtgcaatt tgataaattg attgctcctc atgtaaaaag
    57241 tgcagaagaa aacgcagatt acagcaaaat gtataatccg caatcttttg atacatttat
    57301 taaatacaca gataaactgg acttgaaaaa acttgtcacg ggtttgattg ggacaactcc
    57361 agataaagtg atcgtaactg atccagtgta cttcgatcat ttgaatgaca tcctgacaga
    57421 agctcatttt ccgttattca aaagctggat gatcattaaa acagtacgtt ctcttagtgg
    57481 ttatctatca gaagaattcc gccaagtcag cggaatctat tctcgcgtat tgtctggaac
    57541 agacgaagca atgcctcaga aaaaagcagc gtattacctt gcctctggac aattcgatca
    57601 agtagttggc gattactacg gaaaaaaata ttttggcgaa gctgctaaaa aagacgtaga
    57661 acaaatggtg aaaaaaatga tcgccgttta taaaaaacgt ctagaagaaa atgactggct
    57721 tggggatgca acaaaagaaa aagccgtcat aaaattaaat aacttaggta tccaagtagg
    57781 ctaccccgat aagatcccag cattattcga ccagttcaaa acagtacctg cagatcaggg
    57841 tggtactttg ctttcaaata ctcttgtttt cagcaaactc acattaaaag atcgtttcag
    57901 caaatggaac aaaccagtgg atcgttcaga atgggaaatg agtgctgaca cggtcaatgc
    57961 ttattatcat ccatttcgga atgtgatcgt ctttccggca gcgatccttc aagcaccatt
    58021 ttacagtcta gaacaatcaa gctctgctaa ttatggtgga atcggagctg ttatcgctca
    58081 tgagatttcc catgcatttg ataataacgg cgctttattt gacgaatatg gcaacttgaa
    58141 caactggtgg acagaagaag atcttacaca atttcaaaac aaagcacaag caatgatcga
    58201 agaattcgat ggtctgcctt ttgctgacgg aaaagtaaac ggaaaattaa ccgtttcgga
    58261 aaatattgct gatgcaggcg gtctaagctg tgcattggaa gcagcaaaaa cggaatcaga
    58321 tctttctatc gaggaattct ttgtcaattg ggcaacgatt tggcgtacaa aagcaaaaaa
    58381 agaataccaa caacttttac tgcaaatcga tgtccatgcc cctgctaaac tccgagcaaa
    58441 cgtgcaacca aaaaaccttg acgaattcta tgaaacattt ggtatcacgg aacaagacgc
    58501 tatgtatcta gcgccagaaa aaagagtgcg aatctggtaa gaggttgtgc cagaagtggt
    58561 cagcttcaag aaataagaag gaatttggga aaatcgcttc tcaaattttt gtgacatttc
    58621 ggcttatttt tcgaagaagt tacttctgga ataccatgta ttagaggttg tgaaaaagct
    58681 gcttagtttc aagtagtaag aaaaattttg tgaaaatggc tttccacatt tttgcataaa
    58741 tttgacttac taccgagaaa ctggcttttg aacaccgttt atcgagaggt tgtgaaatca
    58801 gcgtcctgac ctgagtatta gagaaaaaaa cggaaaaata gttcctcata ttttgccgtt
    58861 tgttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag attgtgaaaa
    58921 agctgtcctg catcaagtaa taagaacagc caatcaaaag cagcaaggag aacctcatct
    58981 ataaaaagat agaaggaagt gagacatcta ttggtctcat ttccttctat ttttactttc
    59041 ctcagtcaat tgttttacat cataaaagga gaaattccac ttattttttt cgctgtttca
    59101 tgacataaac aactacaccg attaacaaaa ttcctccagc taatgctagc aacgggttat
    59161 taaattctcc cgtttttggg agtccttgag tgccattttt ttcactttct tttgctgtcc
    59221 tatccggatg agaaggtttt ccatttggtt ttccatttgg tgattcattt cctggatttt
    59281 ctctttctgg tttgtcattt cccgggggca catcggcagt ttctcgcaca gtgatcgctt
    59341 tttgctgggt aacagattct gtatgagcag accatttttc cccatcaaat atttccgaac
    59401 gataagtgac ttctagcgta tattctcctt ttgaaggtgc tgaaaaaata gcggtatgat
    59461 tagaaaattg agcacttgac tgtgtttcaa cgatttggat cttttctggg aaataacgca
    59521 tatcttcaaa gacaggcgtt ccttgatttg gtgtgaaagt tgacacaaaa actgtaaaag
    59581 gcttcagttc aatgatattt ccttctgcat tctccgccac accatttgct tcttgtataa
    59641 taatcggatt attttgttca tttggttttg tctgatttgg ttcttgtacg attgcatact
    59701 ctggatattc cgaagacggt gaggtttctc cgtcaaaaat agcacctaca gataatggaa
    59761 gaccatccac tctttccttt tctgtttgac gattccccgg tttaatctgc atcagtccat
    59821 gaacatggat acttccattt tcatagcgcg taacaggctg ctgaccttct ttcgaacatg
    59881 tatttagaga ctcgatccaa tcttttgata tggtatgtcc aagagtattt tctgattgtt
    59941 tctctcgttc attccaatag tagttcaacg agtggtagat ttgatcttcg ttttgattca
    60001 atgggcggat ctgctctctc atctcaagat tctctgttcg gaaagataag ataccagaag
    60061 catggtagtc tgtgtttcct gctgaagagg tataaagagc cacattatat gaaccgttat
    60121 taaaacttgt actgctattg acgataatat ctgttccgct attggaatcg attcctttcg
    60181 caagattttc gaaagacaaa ctattgatca attcatgagg gcccgttaaa gaagaaccgc
    60241 ccattttgaa tccattaccg ttaccttctc cctcaattcc tggtacccag ccgtttcgat
    60301 aagcaactga gtttttgatg attacttttc cgatcgaacc tgtttcattt ttagcaaaaa
    60361 ggtcccaacc gtcatctgca ttatgatacg cgatacaacc gtcaaataca tttccttctc
    60421 ctattgtcag tttggccgca aatccatcgg catcttcaaa tcctggatcg gcattttcaa
    60481 aagatgtaca gttcttgact aagttatgcg cgggccatgc ttcgaaagga tcatttgagc
    60541 taccgctgat ttggattcct gtatttccat tccgataagc atgaatctct tcgatcaaat
    60601 tatgatttcc agaaatctgt aatccttttt gcatagctgc actatttgta atgtcaaacc
    60661 ctcgtaaacc ccagtagtga ctgaacagtg tcatcccatt tccagttcct ttaaaatcaa
    60721 gtacaggacg cttgttttct ggatttttct ctgcaatcaa ctgaatcggg ttttctcttg
    60781 tcccgttaac gccttttgga atcgtcaatc ctctttcgaa ggaataagtt ccaggcgcca
    60841 tgacgattgt ctgcccagca tatgcgtatc tcaatgcttg tgtcagagat aatggatttt
    60901 gtctgcttcc gtttcctgca tctgaccctt ctggtgttac ataaactgtc gaatatttag
    60961 gtttacggta gtccactgta tgaagaatct cttttgtttc ataactagtc atctctacgt
    61021 attcttctgg cggatagttt ttatctggcg taaaactgaa agtaaattcg ttcgttcctt
    61081 ccatcagttt tgtctgataa tcaaattccc gattcgcagt gatagccaag ttttttgcgt
    61141 tcttaagcac ctctcctgtt gctttatttt taattgtcaa taatccgtca gcatttgctc
    61201 taaaggacat agtatgatct tggtttcctg aatgattact agaggtcaca gtgtaaatcg
    61261 gatcaatcaa gcgagtaggt ctttcttgcc caggaggatc tgtcgcagga tctgagtaag
    61321 caacttcgat tccttctacc ttgatcgtca tattccttgc tgcagcaaat cctgcataaa
    61381 taaccgattc atctgaagcg tataattttt cccagtcata catgatgtca gaagccattt
    61441 cttctcctgt ttcaggatcg taataatatg cctctaaacc agtattcgtt tttttcatct
    61501 ctacgtccag tttagtaatc gagttcgtgg ccggaaacag attcccatga ccgtttccga
    61561 atatattata agaacctgtt tctttttcca agaaccctgc tgaagtctct aaaggtgttg
    61621 tttccactga gacactccca ggagctggcg cagcttgcgg atcttcagat gatattcctg
    61681 tgattgcccg tgtccccaat ccaagtcgca tcgtatattt gctgccgctc gtgttgacca
    61741 cttcttgtct atccgagtcc cagacatatt cgatccgact gcctagtatg gcaaatgaat
    61801 ttgaataaaa tgcctgccca aacaaatgat tttttggtac tgcgtctctt accattaaag
    61861 caaatccttc ttgggcattc gtataggtcc aagattctat ttcgatcgtc gcccgcatcc
    61921 taaagttgat gtctttgggg attgcttgat aataataggt cattccatct gatccgcttg
    61981 actggaattt tccgccgtta ttcgtggaag agagccgcac gccgtcttct aatggttcaa
    62041 tggcatacct actagcactt gtgctttctc cgaaaacaac ccctttccac tcttcatttg
    62101 cttcttcaga ttgctttttt gtcttttcat tttctgattc tttcatcata ggatcatttc
    62161 cttcttccgt atccatatct tcactagttc ttggtatttc ctccattgtt gacatccctt
    62221 caatgttcac gtgtgcattt tcttcgttca cagactgttg ttcgttagca gcaacttcaa
    62281 cgacagaaat taaaaccggg gtactgagca taaggagatt catcattagc gcactgtatt
    62341 ttatacgttt ttttaacaag tgtattcctc ccgtaacaaa ttagaaagcg tttacttaaa
    62401 gtattaccta atttattttt actgtcaata aaaaacaaaa ttataataag tgtattttat
    62461 aaaaagaaaa aatataactt aagttgttga taataaagag atttattaac gtaaaaagaa
    62521 taagtttttt taaaataacg tataaaaaag agcataaaac aaagtcgttt gttttatgct
    62581 cttcttttat tattttgtgc tttttatttt atcaaatcac tttgtttttt tataaaattt
    62641 ctgcgcctag tgtggactca aaatgtctca atgcccattc atgtccaacg ggatcgaaac
    62701 ttgccacggc atctttgaaa atatggagtt tgtatcctag attatacgca tcgactgctg
    62761 tatgcaacac acagatatct gtacatacgc cggtcaaata aatatctgtg atctggcgtt
    62821 ctcgcaaacg gatgtctaga tctgttccac taaaagcgga ataatgccgt ttgtctatcc
    62881 aataaacatt ttcctcttgc tcatagtctt ggtataaact ttttaaagag ccgtacaatt
    62941 cccgtccacc cgttcctatc acattatgcg gaggaaataa gcggttctcc ggatgaaagg
    63001 aatcttttgg atcatgcgca tcaatggcaa aaacgacaaa atccttttga tcaataaact
    63061 tctttgtatg agcagtcagc tttttttcaa ttacttgtcc tgctgtccca gtagtcagct
    63121 ttccatcctc tgcaacaaaa tcatatgtgt agtcaatcga gatcaatgcg ttcatcttag
    63181 tcctccttat acgagatgtt tgacaaattc gatcaccatt tctgctgatc gtttgcctgc
    63241 gtcttcgata aattcgtcaa agctttgtgt cgccgagtga tctgctgtgt cgctcattgc
    63301 acgtacgatc aaaaatggga tattgaactg acgagctgtt tgtccaacag cggctccttc
    63361 catttcgcaa gctaatgctt cagggaaatt cgttaagatt tctttgattt tatctggcga
    63421 gtcgacaaat gtatcacctg taacgatcaa tccttctttt gcgttcaaat tcgttgcttt
    63481 tgctgcttta accatttcac tgcgcaaata tgtgcttgct tcataatata gaggcattcc
    63541 tggtaattgt cctgggttgt agccaaatcc tgttgcatct gcatcaaaat aagctacttt
    63601 gtctgatata acgatgtcac ctacttgtaa gccttcaccg attccgccag ctgaacctgt
    63661 attgatcacc atgttcacgc cgtattgttg gatcaacaga cttgtggtaa tagatgctaa
    63721 gacttttcct ataccggaac gtacgacgat cacttcgtgg ttacctaatg aacctgaaat
    63781 aaataaagcg cctgcgcgtt cccatgataa tggttcgctt aggttctctc tcaaaatttt
    63841 tacttcttct tccattgcgc cgataatacc gattttcatc tttttaattc cttctttcta
    63901 tataaatgcg attgctaaaa aaaccacaca taacattagg ataacaataa taagagattt
    63961 catcaaaaaa gagttccatt tggtcgtctt ttcccgttcg ctgatccttg ttttcgtgat
    64021 tggtttattc tttttgcttt ctttacgata aaagctggca atcttttttt cttcttgctg
    64081 ataagctgtt tctgcttttc gctgtttttt taatgactcg cttgcttgtg cttgttgtcg
    64141 cttgcgaagt tcgcttcgcg taataagcgg tcctttggcc ataagccgat ccctctactt
    64201 tcctttggtc aatagttccc agtattgaat cgcataaatc gtctttgcat cacaaatcaa
    64261 ctgatctttc atcgcttgtt gcgcctcttc aagagttaga tgatacaact ccagtacttc
    64321 gtcttcatct tgtgctaaag gattctcgac cttctctacc ccttgtgcat gataaatatg
    64381 aaggacttca tttgcaaaac ctggtgaaag atacatcgaa gtaagatggc tcagcgactt
    64441 cgcacgatag ccagtttctt cttctaattc tctagctgct gtcatttcgg gattttgtcc
    64501 ttctcctgga tcgatttttc cagctggaat ctccaaaatc actttttcta aaggttttcg
    64561 aaattgtttg acaagaagca gacgatcttg ttcgtcaaaa gcaatgatcc cgacaccgcc
    64621 aggatgaaat accagttctc tcttcgaagt tcctccatct ggcaaacgaa cttcgtctac
    64681 agcaacatca ataatttttc cgctatagat ttctttgcga ctgattgttt tttcttcaaa
    64741 ttgctcattg ttcagcatat cttctcctgc tttctttgta atcataactg cttttttttc
    64801 atttttcaat ttttctcaaa aactccttat tagtttacca tagataaacc ttagattttc
    64861 tctaaatata gaaaatcctt ctttagtccg atactcttta tagtagtccg tatgctaaaa
    64921 taagtatgta atcgaataac gaaaagaatt caatactcaa cgataaatga catggagggt
    64981 ttattatgat aaaacgaaat tggccgtggc ttctagcatt ggtcttgcta tttctctttg
    65041 tccgaaacaa tagtttttct tttgttctag gacttttatt gataggtgta gttttagttt
    65101 tgtggggact ctttggttcg cgcaggaaaa agggaaaaca agaagaaatt cctgcactga
    65161 ctgacgaact tgaaactcac tatgaaaaaa gcggtatgac agcgaatgaa atttcatttt
    65221 ttcgacaaac aatgaatcaa acaaaaaatg agatcaatca attgcaaatg aatatgcagc
    65281 agacagccaa acttaaagca atcgatctcc gccatgatcc agtcaaagca gcgaaagctt
    65341 tattcaaaga attggtgaaa gaaccaaacc gactgcatga agcaagtcag tttctttata
    65401 cgcatctgcc gaatctagtt gatttgacaa ataagtataa tgagatcaat gaccatgaga
    65461 tcaaaaacaa acagacctat gaaaaactag aagaaagcgc gcagatcatc gaccagctgt
    65521 cagctttaat cgcacaagat tatcaaaaat tcgttgctga ggatctagat gatatcgacg
    65581 tagagatatc tgttgcgaaa cagagcttaa agcgtgataa taaatatgaa ccagaacaaa
    65641 aggattaact cttttgttca taaaagaaga ctcggaacat tcagatgatg tctggctgtt
    65701 tcgagtactt tttctaaagt agagacattc atgtaagaat cgagaacaga ttcaacaagg
    65761 aggaattttt tatggatcat aaaccgactg aaacaaaaga tgttacacca gttaacgata
    65821 cacttgaaga tttattgaac aacccgtttt caactccaac agatacgctg accacttcac
    65881 aacaagcgga gattgatcag ctccaagagc aacagacagc tgctcgttta attgacaaac
    65941 taccggcgga acgccaagaa caagctaaac agctagcagc aaaaatcgat gctaatgatg
    66001 cacagtctgt catcagctac ggatcggctg cccaagcaaa attaagtgaa ttctcacaat
    66061 cgatgttgaa tcatgtgcaa gcacaagata ttggtcctgt aggagattcc ttaactgaac
    66121 tgatgtatcg tctccaagaa gccaatcctg acgaactgcg tgccggagaa gggaacatct
    66181 tccagcgtgt cttcgggaag gtcaaacaat cgatctatga agtgacagca aaatatcaaa
    66241 agattggtgc acaaattgac aagatttcag tgaaattaga taaagaaaaa gacggtctgc
    66301 taaaagataa tctgatgtta gaacagcttt accagaaaaa caaagactac tttgatgcac
    66361 tgaatattta tatcgctgct ggagaattga aaatggaaga acttcaaaca acgatcattc
    66421 cagaagcgat gaaaagagca gaagaaactg gcgatcagat ggatgttcag attgccaatg
    66481 attacacgca attcctagat cgtctggata aacgtacgca tgatcttcgc ttagctagac
    66541 agatcacgat ccagcaagca ccacaaatcc gtttgatcca aaacacaaat caggccttgg
    66601 ctgaaaagat ccaagcatct atcgctacag ccattccgct gtggaaaaac caagtcgtga
    66661 tcgcattgac cttgcttcgt caaaaagatg cagtaactgc tcaacgccaa gtctctgaaa
    66721 caacaaacga cttattgaag aaaaattcag aaatgctgaa aatctcagcc atcgaaacag
    66781 cgaaagaaaa tgaacgtgga atcgtggata tcgagaccct tcaaaccact caaaatgatt
    66841 tgatcgaaac aatccaagag acattgcgta tccaaaaaga aggaaaagaa aaacgtcgtc
    66901 atgcagaagt agagcttgga cacatggaag aagatctgaa acaaaaactg ttggatttaa
    66961 cccaatagat cacctttcgc ttgttactaa aacaaacgcc caacaacagt ttattacaac
    67021 tgttgatggg cgtttttctt atctttcttc taacttctcc attggagtct atttctcatt
    67081 catcttgctg tgtccatagc catagccaaa ataaatgatc agtccaataa ccattacgat
    67141 accgaacacg atccatgtca cagtttgcag acgaagcatc aatacaatac aagtcaagat
    67201 ggagacgatt ggcaatagcg gaacgaatgg cactttgaat tctccagctt ttggtttgcc
    67261 aaacattttt ctcaacttca gtaagcctag actaacaagc atcaaatagg cgagcgccat
    67321 gatattcgtt agttccgcta atacattcaa tgggaaaaat ccggcaaaga atacagctgc
    67381 cacaccagcg gcataagtcg cttttttcgg tgtacgatgc ttttgatcga tttctgtcat
    67441 aaacttagga agtaagccat ccttgctgac agcaaacagt aaacgagcaa gtgaatacat
    67501 catcgagatc gttaccgtca gtagcgttaa aattgcccct acagcgatca ccgcgcccac
    67561 tgttccatgt cctacatacc tcattgcaaa agccactggg tcattgactc ctagttcagt
    67621 atacggaacg attcctgtca agatcagcgt cacgatgatg taaaggacag tagcaatcag
    67681 tatcgaacca atgattcctc ttggcacatc tttttgcggg tttttgactt cctcggctgc
    67741 cattgcaacg gcatcaaatc ccaagaaagc aaaaaacaca agagctgcac catctagcac
    67801 accggaaaaa ccaaaaggca tgaatggctg ccagttatca ggtttaacga aaaatattcc
    67861 tacaatgata aacaacgcga tgataccaaa tttgacatat accatggcat tattcaaacg
    67921 taatgctttc ttggcttcaa gcgacacgat gtaagtgacg aatatcacta cgagcaccgc
    67981 aatcaagtca atgtatgtac cattttccgg attgtacccg ccagttaatg cttgtggaag
    68041 ttcggcccct aaacttttca aaaaaccttg catatagcca gaccatccgg aagcaacaga
    68101 ggaaaccgct agtaaaaatt ccccgatcaa caaccaccct gtcagccagg cagcaaattc
    68161 accaaataca acatacagat aggcatatgg cccaccaatc actggcactc gcgaagcaaa
    68221 ttctgcgaaa cttagtccag acaaaatgac aacgattgca gctaagacaa atgaaagtga
    68281 cagtgctgga ccagcatttt gattggccgc aacccctgtc accacaaata ttcccgtacc
    68341 gatgatcgca ccaattccaa gcatgatcaa atcagacgtt tttagttctt ttttcatctc
    68401 actcgtatga ttgagattga tctctttctt acgaaacaaa tccattgaag ttcctcccca
    68461 ttttaggttg gaaaacagcg attaaactgt tttcatatac cctaaaagga taccacctaa
    68521 aatgactaaa aggcaaccaa caataacata aatgagctct tttttcgttt ttctttcgcc
    68581 aaggatgaaa atcccaccta aagtagagat aatgatcccc atttgtgaaa gtgagaagcc
    68641 aacagctaaa ccaagtgatt tgactgttag aagcatgcag atgtttccta agccccataa
    68701 taatccacag atcatgtttt tccacacaaa ctgatcgact ttaactttac ggaaagcaaa
    68761 gaagcttgcg cctaagatca ttccgatact ttgaggtaag ataattgaca tcgcatccaa
    68821 attcgcccag ttgacgatga tggtatatac accataacca atcgtagaga agatcaatgc
    68881 tctaaaaccc ttaccaaaat caagcatttt attatctgta tctatttttc cttcgtcatc
    68941 ttgtcgggca gtcaaatacg caccgcttac aagaagagct aaagcaataa taccgtatac
    69001 ataatctttc gtttgtgtcc attcatggaa gaaaacggct cccgcaatcg tattcaaaat
    69061 taattgaaaa ccagtagaca atggtagccc tacagaaaca cccatgtact tcattccatg
    69121 gaactgtcca ttttgtccaa cactccaagc taagccggat aaaaatccga tcaagaaaat
    69181 ccaaggggtg attacaggac taacaacgaa aaagacaact aaagaaaaca gaaatgcacc
    69241 gatcgtcatt cctagtgttt gttgattggc atcgccacca attttaccac ttactaaacc
    69301 aatactaccc catgccaaca tagggactaa tgctattaaa atttccataa ccaatctcct
    69361 tttatttcac atgataagaa acttatcagc gaaaacgtta acaacacaag cacttttttt
    69421 cgtttctaac gattttctaa cgtttttcat tataaaaatt taagattggg aaaaataaag
    69481 tcattgttgt cccttttcct tcagttgatt cagccgtcaa atggatacct aatttttcgg
    69541 ccagattttt tgctaaataa agtcctaatc ctgttgaatg tgttttgcta agtcgaccat
    69601 ttctcccagt aaatccctta tcaaagatcc gtttcaagtc ttccgctggg ataccgatcc
    69661 ctgaatcttt aactgaaagg ctgactcctt gcgcttcctt ttctatgctc acaatgatgt
    69721 ttccgtgatc cggcgtatat ttgatggcat tactaagcaa ttggttgaag ataaaagcga
    69781 tccatttagc atcggtcaaa acagtatgat cctcaccaac gatctcgtag cgaatatttt
    69841 tttggataaa ataatttgcc tgactgcgta tcacaggctg aatgattcct tttagtccat
    69901 attcttggat gaggtagtcc cgcgagaaac tgtcgagtct tgcataatac aaaacttgtt
    69961 ctacgtattc atcgattttt gataattcat tttctagtaa tgtatacttt tgatcgtcaa
    70021 tatcgaactc gatcgaacga actagcaatt tagaagcgga aagtggcact ttgatttcat
    70081 ggacccatga gtcaatataa tctttttggt cttgttgatt actgattgct gattgcatta
    70141 cttcttggtg ttcacggatc agctgattga tatattcttc taccagtttt tcttcttctg
    70201 tcctcccacc actcaaataa ttttgcaaag gggaagtttt ttgtatgtcg gctaattttc
    70261 cccaccatct tctcttgctc aagtaaccac ccagcagata aaaaatcaga aagacgccct
    70321 caatcaaagc taaataagca attgtgctca aatcaacttt gatgtttggc gccagccaca
    70381 tcacaaagat cgtcaatgca ataaaaaaca gccatcccaa gatcaatgtc cactgatctt
    70441 tcaaatattt aaaaaaattc atcttaaccg ctcatccttt cagggaacga tatatccctg
    70501 tcctactttt gtttcgatat atccttggat acctgcctgt tcgatttttc ggcgtaaccg
    70561 attgatgttg actgtcaatg tattgtcatc tacaaatcgt tcgtcatccc acagtgctcg
    70621 cagcaatttt tcccgactta agatctttcc attgtgcttc atcaaaataa ataatagacg
    70681 atattcattt ttgctcaaat caatgatctc tccgttgatt tccatacttc cgttgtcaac
    70741 attcaacgta atgccattgt ggctcatcat ttcactagat aattctgtgt agttgtaaga
    70801 acggcgaagt aatgcattga tttttgcaat cagtacatcg atttggaaat gttttgtcac
    70861 aaaatcatct gcccccatgt tcatagccat gatcatatcc atattcgtat tcctgctgga
    70921 gataaaaatg atcggtactt tcgatacttc acgtattttt tgacaccaat aatagccatc
    70981 caaaacggga agattaatat ctagtaatac aagctgtggt tcttctcttt caaagtctga
    71041 gaacacttga ttgaaatcgg tcgttccaaa ggtttcaaat tgccatttct caagttcctc
    71101 catgatcaat tgtcgaatga tctcttcgtc ttcgactacc atgatttttg ccataaaaaa
    71161 tccctccatc tttcttcttg ctactacaat atcaaagaag cccttgtgaa acaagttggc
    71221 ttacctggaa aatgtcattt tagcaaacgt taaaaaaaac tggaaatatg cgatttaatc
    71281 gcgtttgtct cttccaagca gcttaaattt attatgttat tcttaataat tggtctatta
    71341 tctgttattt ttctttcgtt gtttttgtct tttaaatttt cgataacacc aataaccgaa
    71401 aagcgttagc actagcaata tacctagaag gagtataagt aatcgataaa gatggtattt
    71461 ttttgtctgt tctatctttg aagagacttc ttctgtaaag ggaactcgtc ttcctgtcac
    71521 tagtaatcgg tgagtgttca cggtgtaagg tgtacaagtg ataagtgtga ctagatcctg
    71581 cttttctcta attgctaatg tatttgtttt tgttggaagg acaacaattt tctcaacgac
    71641 ttcataagcg agcatccgac catacacttc aagatagaat cggtcatctt gctccatttc
    71701 ttcaagatcc gtaaagagtt ttttctcagc aataccgcta tgggcggtaa tcacggaatg
    71761 tgtactctct cctccagttg gaaaagaggt gccttgcagg actgtcgctc ctctatctaa
    71821 caaaagatca ttcgtttcat caaataaagg caagctaaca ttgattttcg gaatatagat
    71881 ggctccgatc atatgttgtt cgtaatattc ttttcctgga ttttggacat ttctaaccgc
    71941 ttgctcaaaa ggatctttga cttgtcccat tcctgggatt actgatgtat gagcaagcgt
    72001 ctgatttttc ttttcatgca ctgctaattg ttgctcatgt ttttcttctt tatcgcgttc
    72061 aagctgcttt tgataattct cgatccttct ttgatccaaa taattgctga gagcatctgc
    72121 taaaaatgga tatgtaaaaa ctgcagctcc ggcaagaaac atcactgcca taaataattg
    72181 taataaaaga ctgatttggg tttgaggtct attacctatt ttctttttca ttttcttcac
    72241 cttcttattt aaaaaaactg cagcaacctt tataaaaccg attgctgcag cttatttttg
    72301 ttgcttatac ttcagacttc attttagatt tacggtacca gctgtacgct ccaatcatca
    72361 aacttattcc gattagtaag aatgccaaga gcccgttccc accagtagca ggaagtgacc
    72421 cgcgtttcat attcggtact ctttctggcc ctggattttc tactcctacg atctgaattt
    72481 cttcattata gcttccataa gagatgataa attcagtaaa ggctgcctca cctgttggaa
    72541 gtacataacc ttctggcgcc atggtctctt tcatttgata ggttccataa tctaaccctt
    72601 gaacctcaaa gtatccattt ccatctgcga caaattctgt tgcttgtccg cttgttgccc
    72661 actcaattct atctgctcct gattcataaa cagctaaagg cgactcccct ttataaaata
    72721 ttgcgtattc agaacggtct tcattccaca attcgaatct tgcatcttta agcaattcac
    72781 tgcttgatgc atcatatttt tcaaactttc ttccacctgt tgtgactttc tctggcggct
    72841 ctactccttc ttcataatca aattcatcat ttcgtccgat ttcaataacc gctgtgttgt
    72901 tatggaaatc atccgcttct agttctgtgg aaaccttcaa attatatgtg atcgttaaat
    72961 ctcctccacg tgcatctgct aatctaccta aagtatctac tttggctact ccattttctt
    73021 ctgtcaaaat cgtcacgaca aacccgttgc ttactacttc tactatataa tcttgtcctt
    73081 ttgttaaaat cgtctcgccg gctcgcactt ctatttcctg atcataataa gttagaccaa
    73141 ctgtaggcgt atctgtgatt ttgtaatttt tgataacagc gcttccgttt tcaaggacag
    73201 aatcgatgaa ataaggaata ggtgctgtga tcgtgtaaga agccgttttt cctctttcta
    73261 gatcaatata agaaatcgtt tcttgttctc cagcttcatt aataatcgtt acttgtctaa
    73321 ggtcgctttc ctctacattc atctgtttat ctgcttctct gatttcgttt ttcggataca
    73381 aatgcacatc tgtattgtat gtgtctttcc atgtagaacc atcccacacg ccatccacca
    73441 tatcaggcat catcactggc atcataacaa ccattggaga cgcgattctg gaaatatgag
    73501 ctggcgaata agtttctaag aaaagataga ctttatctct agaagaaggt gcttcttccg
    73561 tcacttggac ggtagagaat accgcttctc cagcttcatt cgttgtttgt ttgtcaatac
    73621 ttgtcagtcg atattttaaa aaccaacttt ctgtgtgccg tttttgaatc cattcaatcg
    73681 cttcggcaga attaagaccg tcttctcgtt ccggtgttaa aggattatct cgaatcaaat
    73741 cgtaatatac ttccgttacg tcaaacaaat caaaatcgac tcctggaata ttttcttcac
    73801 caaaatccgt agaaaccaat ccgctattcg gtcgttcttc cggaacagat gagaaacctt
    73861 ttttgtgtaa tgtaatcgtc acttcacttg gtttttgtgc gacttcttcg gctttgacta
    73921 gttttccgtt cccgaaaatc cctattcccg cagtaacgag taacagtaca ctcattcccg
    73981 tgacaatcat ttttttattc atttttttct ccccgttctt tttttattaa taaaacagca
    74041 cctaacaata aaagaattcc tagtaaagaa atcaacgttc ttgcttcatt cgtttgcggg
    74101 aatacggacc attttcctga ttgacctgga ttgcttggac cactcggctc tttcggtttg
    74161 tccgttgttt cttttacggt ctcgttataa acacgtggtg ttgcggattc ataggcagag
    74221 actggaactt tcccggattc taattcagcc atctcctgtc cgttaactac tacatattgt
    74281 ggttggcctt ttgcatccac ccaaaattca gggatgatga cctcgattct cttacttgct
    74341 tcatccatct cgtaaccttc cacacctttt aattcttcaa aataataggt gccagaaggc
    74401 aagaaacgtt gtcctgtcgt aacaaggccc tctttatccg aaatgaattt gcttacattt
    74461 ttgtcattca aaggatcatt gtctgctggt ttgatccatt gatttttcaa gtcattagca
    74521 ggagccatat ctaaataata tttcccccct tctatcatct gatatagagc aaaaacagca
    74581 ccttctaatg gttttccttt ttcagttgtt cctctttgac gtccatactt gaagaagtat
    74641 ggatctctta gataaccgac atttttagga tagatatgaa tctcttgcag ttcctcggtt
    74701 gattctgtcg ggtgataaat tggcaaaata gcagcaattg ggatagctgt ctgatcgata
    74761 tcaacatcca atccaacttc tggatcaatc gattcttcga aaatcaaata aactgcatcc
    74821 cgatcttggt ttttcttagg tgctttgata cgtgcaatcc cgtctcctaa tccgccaacc
    74881 gtatctttcc cagttgttac cgaagtccct atttggacaa gcctttcttc tgtgattagc
    74941 tgacggatat tgtttctgtt cgtttcagcg atttgctgga cgaattcttt aggagtcatg
    75001 ttttcagcag cttttttttc atgataataa tcggtcatgt cgtaaatggc aaatgtcgct
    75061 ccatttagtg gcaccgtctg tgaaatgata tctgctgttt cccctgcttc ctcagagata
    75121 gccaagccat cattttcatg gtattcaaat tgatcgttat aatcgatatc tcgaatcatc
    75181 cgtttatgca acacgaattc cacgacatct tcccctgatt cttctgccga catcgcatgt
    75241 ggaagaagga ctgctgcaag cggtagtaaa acaagtaatt gaagcatcaa acacaacagc
    75301 tttttcatta ccttgctccc tcctttttag attgtctgac aaacaaacca taggctgctc
    75361 ctgcaagcgc catgaagaat gcagcaagca ggatatagaa taatcgtccg gatcctcctg
    75421 tagcaggcaa cggattttca ggatcgttcc cgacactaag ctgtaatctg attcgatttg
    75481 tctccaaaag ttcatattct aactcttgct gtagatcagg cgtctctgct tcttcgtttg
    75541 gataatacga aatctcaact tttagtgtac ccgcttcttt tcctggaact acccgatcat
    75601 tttctatgtc aggttcttct cgataactaa tttctaaaat aaagtaacct ggaagttttc
    75661 tatagctgtc aggtgacttc acttccttga tccgatagac cccttccaac aagtctgaag
    75721 cattgaatag ggaagaatcg tttggatctg gtgccaagcc tccctcgatg atttcatact
    75781 ctcctgcact attttgtttc tcaattgaaa attctgcgcc ttcaagacgt cggctattca
    75841 tactgtcaat tttcaaaagt tccaaatcga ttggcgctag ttcatcttct aaggttactt
    75901 gtagtacacc atcgatgatt tcatagcctt ccggcaaggg agcagtttcg tcttcgatga
    75961 ccgtatcttc aatgataaac ttaccttctt cattcagtgc aaactggaac acttgatcag
    76021 atagccgata cccatttggt gcgacagatt ccgagacctc atattcacca atagacagat
    76081 gcagaggttg gtcgtaattt aaatcgacat acttttctac tcctacggca cgagaataga
    76141 agtatccgat cccaggcaaa cgtttcgatt cttctggttc taacggatta ccagtgtatg
    76201 ctcgatacag cgggaaggaa gaatccccca ctttcctgat atcgaaacct gcaccatcta
    76261 atgtatggcc ttcatggtct aattttctaa ctcggatctc ccgataatca aacgtattgt
    76321 aagcagtgaa tgctacccat aaacgatcct cttcatctgt tgtatacgtg agatattgcc
    76381 aattttcttc acctgtttgc ttgagttgga tagtccctat agcattatcg taaagtcgca
    76441 agatccatgt gtcattttca tcaggttctt tgaaaccttc tgggttctgg ctctcaatga
    76501 ttttgtattc tgcatagttg gtagtttctt cactatcctt ataaacaaat gaatctggct
    76561 ctccgattgg atgaataact ttctcaccat ccacgattac atatttcccg tcttcatcta
    76621 ctgaatagaa cgtgagtctc cctttctctt cctctacttc gttcacacca gaaagccctt
    76681 tcgctactgg atatccgatt tccagtccgt taccatctgt ttcataaagt tcaaactctg
    76741 cgccattgat tggcatatta ctgccttcaa ttagtttatt gatattcatg tggattggct
    76801 tgaattcatt tcgcatttcc agtttgacat acaactcatc atactctgtg ccttctatgt
    76861 taggctcttg tacaacagaa agcttgtgat attctccttc ataataggaa ttcggatctt
    76921 taccttccgg tccgccgact ctcgaaccag atgtatattc atctacaagc tcgtagtgac
    76981 ctaacatctc atcttcgttg gctgcatatt ttttgatttg gaattgatac gtctcatcta
    77041 ctaactgata acgtggtggt ccagcgatct ctctgatcca aaatatgtcg ctgactgctc
    77101 cagtttcatc tcctaaaatc ggcatcttcg tttcaaagat cgctattccg tccgtggtag
    77161 ttttacttgt ttcgattggt tcggcttccc cactctctgg attttggtca tataatgcaa
    77221 attcgactcc agccaacggc tcgccatttt gacccttctt gctgacttgg aaattacggc
    77281 ctttatgttc gtaacgaatg gaagaagatg ggaaatacat ccgtccagta gtgatatcat
    77341 tctcataatc ctccaggttc tgaatatagg ccatattgtt cactgtgcaa aaatttccgt
    77401 cttgagctcc cgcatcaagt tttacttggt acttgatcct gaccatttcc ccttcaccta
    77461 aagaaatcgg agaaaattta taagcttggt tttcccgtcc gacatacgtt gtcggagtcg
    77521 ccactacttc tggtggggct tgtccatgac gttcttcatc ccatatttct ggctcttggt
    77581 acttcatgcc gttttctcct ggatctagat ggtaaaactg aatatctgcc gatctgccag
    77641 ctccaaatgg tgagacatta aaaccagttt catcataaag tgtggcttgc tggatcgttc
    77701 tcttgaaggt agaagagata tcctccaagg ctgtaacaat gtcattcttg ttgttcgcat
    77761 tgtaatatcg cggtgttacg ccatcttctt ctaaatcagc aatatttttc aatacatttc
    77821 gtccaatagc atctagtcgt tgtctcccgc taacgtttcc atcgattcct aaaccaatgg
    77881 agaagatact tggcgggttc tcttgatact tgtttttcag ccaatgatga taagcaactg
    77941 tgttgatcgc agatgacttt tcttgcgaag taggactgcc attcgtattg ttattagaag
    78001 aaccatcacc aacccagtga gtcgctttat tatctccttc ttttacctct ccataacgat
    78061 agtgtacatt tacttcatct tctggacggt taaagtcaga tgcataggta actggatgag
    78121 taaaccctgc attagaagta ttcccagaaa actcctcaaa atttctgaac aaaacgtcat
    78181 tatcttcagc aatcttatct tccatcacag tccagttgct ccaagctcca ttagtgctcg
    78241 tacgataact tgactgaatc ggtgcataac tgaaggtcgg tgtcccatct cccacaacga
    78301 ttaggatttt ttctggattt ctattttctc cgccattgtc tttatacaat gtttcatagc
    78361 catttttaag ccctagtgta agcggagttc ctccgattgg tgtacgattt aatgctgtat
    78421 tctcacttcc cgtcaaacga ttgatatcat ttgtcaatgg aaagatgtcc gaactgattt
    78481 gctcatggtt attgatagct gtactattat ggtaaaaatt caccataccg attcgaatat
    78541 ccagactcgg gtcagagagc agatctttac tcatttcgtt tactgcctca atcaacgcag
    78601 catttttagt ttgactattg gtcccagcgg ttaattcact catactcgct gacttatcta
    78661 gaacaaaaac gatatcgatt ggactgattt cctttttctc gcccccgatg acatctagat
    78721 agacattgta aagggttgtt gcatcttcag gatgtagatc agatgctgtg ctgcttggca
    78781 gaacaggttc tacccatttt ttgatgtacg ccccgttata atccaagtaa ctgttttcaa
    78841 aattccgttc atttccccaa agctgaacgg tttgagctgg aacgtttcta tcttcttcgc
    78901 ctgcagttga tccattatta gtagcatagt cgtaatttcg ccagttcgct cccccgtttg
    78961 tataatcact atcatcgatc aagttctctc cgtcatatgg cgagcctttg tctccttgat
    79021 agcgttcatt gctttgtgtc caatttccta acacttttgt atagtcattc gttgtaaact
    79081 tcatctattc tttcatcaac caccacttga agaggtagtt acccttcgtt cacatcgggg
    79141 atcttttctg tttcaaaaat caatgtgccg gtttctgctt cttttgaata aacttttccg
    79201 acataccatt cttgaccatc gatcgtctcg acttttaggt cttctccatc ttcatcatag
    79261 gaggatagac ctgttccacg aacgtttttt acggtaccaa tcccggcggc tgccgcatcg
    79321 attgctaaac gtattctacc ttcattggca ctttcctttt tttcaaaagc cagatgccat
    79381 tcaagggttt cttctttttc aatatacttc ccttcaattt ttgcatagtc ctcatctaag
    79441 aatacctcat cctcctttgt ttctgttgac tcagcagcta catccagggt cgtcatatga
    79501 tagactgact ggaaatatgg tccaaatagc aaactgacag ttactaactg caaaagcttc
    79561 aattttaacc ctttcacatc cttatactcc tttcaaaaat atttgtcttc tttcacaaca
    79621 atcaacaaaa caatgcccat ctaattataa tttaatttaa ttttaatttt aaatcaaatg
    79681 atatcctttt tagttaaaaa acaccaatta tacaacattt attattaaaa ttaaattata
    79741 aaattttata acgttctcat ttaacaaaac ttaagttatt aagacaaatg aataaacaac
    79801 tacgctttcc tcgaaacaaa aaaataaagc acaaatgcgc atttacgcac tcatgcttta
    79861 ttcgtacaat taattcagat aacggcagcg cataggatgc caataacact tcctaaaata
    79921 gctcctccta aaatgtcagt aggataatgt aaaagtaaaa aaatcctcga ataagcgatc
    79981 aaacaagcaa ataaaaaggc taatattcct gcaactggac ttaattcgaa caacgcagct
    80041 actgataaaa aggctagcgc tgtatgtcct gaaggaaaag aagaagtctt cggtttactt
    80101 gtgtaaagga caagccgacg atttttttca taaggtcttt tccgtcttgt cgtttttttg
    80161 ataaaaagca aaccaacaaa aaaatagatc aaactgccga taagaatggc tagaccatat
    80221 tctctagtat caggtatcaa gactaaaaca gcagcaagga gcaaccaaat aaaaccacca
    80281 ttagagatat tactgataaa tttcaaaaaa ttgatttttc gactatccgt tttccgttgc
    80341 ttggcgaact tgttgataat actatcatcg attttagcaa tcaaacgcaa catgttattc
    80401 ctccttttta agaacctttt cttgcgtacg atggataaaa agcaggactt gaaaataaaa
    80461 caagaaactg aaacctaata aagcaaaata gattggtcct gcaaaccaga atgcgacaag
    80521 aaggatcaac gtgcctgcca aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa
    80581 aaatgcagta atccaagaag cttctttttg ttccagttga agcaagattt tgtaactaaa
    80641 gagaagcgcg cttaatagaa gcaaaaacaa cgtagtatac atcaatgtat agccaattcc
    80701 cccaccccaa tagcggaaaa tctgataatc gatcaataga agaagaaaat aaacacttgc
    80761 taaactatct tgctttccat aaaaagagaa gttctcacga aactttttcc agaatagtga
    80821 accgagcttt ttctcttcat tttttttgta atgataaatc atatacagaa ctgttcgact
    80881 tgcagttcct aatgtgaaaa caggcaagac gcacaggaac catagtagct gtaaatggat
    80941 aagacgtgga atccattcaa tgatttctaa gaaataatca ttggcttttt taccaatcga
    81001 tcgattcatc atccttttga acctcctgtc aaatccatcc cttcaatgaa ataacgttgt
    81061 gcaaaaaaga acagcaaaat cgtcgggatc aagacaagtg ttgctcctgc catcagataa
    81121 ttccattgtg tcgttgcttg gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt
    81181 tcttgatctt ggatatataa cagaggacct aagaaatcat tccaagctgc gttgaaggaa
    81241 ttgatcgcaa tggtaatcaa ggcaggtttc gtcaatggaa gcatcaaatg actccaaata
    81301 tacaaatgat tcgctccgtc gatttcagca gcttcgatca attcattatt gatcgataag
    81361 taaaattgac gcatcagaaa tatattgaac gcattgccga agaacgatgg aacgatcagg
    81421 ggcaaataag tacctaccca gccgatcttg gagaataata catattgagg gatcatcgtt
    81481 acaaaccccg ggatcatcat cgtagaaaga accaaagcaa acatcagctt tttcccagga
    81541 aaatcaagct tcgcaaatcc ataagcaata aaagaatttg aaaggacatt accgatcact
    81601 actagcacag tgatgaataa tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc
    81661 gtatccagat agttttccca tacgattttt tctgggaaaa aggtcggagg ataacgaacg
    81721 atttcttcca ttggtttcaa tgaagtaaac accatccaaa gcaatggaat gatcaaaatg
    81781 attcctatta ctgtcatgag gacataactt agtatttttt ttgtttgccg attcacactg
    81841 gtctttttga aataatccat catttgccgt cacctccaga ataatagacc cacttaggtg
    81901 caagcttcaa attgacaaac gtcagaacca acacgatcag aaacaggatc attgacatag
    81961 ccatcgcata acccatatca aaagctacga acgccttgtt ccacatatgc agattataaa
    82021 aaagcaaaga atttgcaggt ccgcctgttc catttttcgt catgacataa gcttcttgaa
    82081 aaatttggaa agaaccgatc gtagaggtga tcacatcgta aaaaataata ggagtgatta
    82141 atggcaaagt aatacttttg aactttcccc aaacgcctgc tccatcgatt tctgctgatt
    82201 catataaaga tctaggaaca ttttgtaatg tagctaagta aagtagcatt gctcctccag
    82261 aactccatat tttcatcaaa atcaacgcag gtttcgtcca ttgtggatca aacagccaag
    82321 ctggtccagg gatatggaac cagcccagaa atgtgttgat caatcctgca gatggagaaa
    82381 gcagctgcat ccataagatg tagactgcta ctcctgataa gactgccggt aaatagaaag
    82441 ctgtacggaa tacactgatt cctttgattt tttgattgag tactgtggct aaaaacacac
    82501 tgaaaatcgt cgtcagcggt acattgaaga tgacgaaata aacggtgttg tataacgatt
    82561 tccaaaataa atcatcgtga acgaacattc ttttgaaatt tgctagacca atgaaattca
    82621 tcttggatgt caaattataa tcggtgaaac taccaataac tgaaaaaagc ataggcccta
    82681 gcataaatac caagaacccg ataataaaag gcgagataaa taaataggcc catcttgctt
    82741 cttttttctt tcggatagat aaacgcttca aattttcttg cctcctctgt acctagacag
    82801 tcaaaaatgg attattgatt ttgcttgact aagttttcta ctgctttttg tgcatctgcc
    82861 aatccttctt ttggtgattt tgttcctaaa agaatctggt caatctgttc attcactaat
    82921 gtcgtgtaat ccggagcatc taaaggaact ggtgtgatca ccgtattttt aaagttttcg
    82981 tccgccattt gatagatcat ttttccttta tccgttaggt tgtcattatt cactaaattc
    83041 tcattggctg tcttgctcgc catgatatca aaactttttt cgccgaattt ttcttgtact
    83101 tctggagaag aaagatattt gatgaattca taagaggcct caggatcttt tgctccgtat
    83161 ggtacttcca agacgaatcc gccaccccac gaccaatggc ctgaaccttc ttctttttct
    83221 gggagctgca tcacgccaaa atcaaaatca tccggtgcat tttccatcaa actagagtaa
    83281 taattgatat tttgggcacg catggctact aatccggaaa taaatggatc agatacacca
    83341 gacccaaatt cggcttctaa tttattgatc gtatttttcc cataataatc ttgccagtct
    83401 tggatccact ccaaggcttc cactttattt ttagtatcaa tcttgacttt ttcatctttg
    83461 tcaaaccaac tagtcccgtt atctgcgttt agcgcccata catcagcccc taaattccat
    83521 aatggataaa aaccgatgcg tgtaaattct tttccttctt ttttatctag tttacgtgct
    83581 gtttcttcta attcatccca agttgtcggt agatcttgtt cactgattcc agcttcttta
    83641 aataactttt tattataaaa aatgacttgt gtatctgtat tgaatgggat cgcataagga
    83701 tcaccttcat attctactgt atcccaaagc tgcggataaa aatccttaga agtgtctttt
    83761 tctacatatt tggagagatt agttgcttgc tgtgcttctg ctctttgggc aacggaattt
    83821 atgtcctgta caataacatc gggtgcattt ccagctgtta ttgcagataa agatttagtc
    83881 cagatgtcac cccatggctg atacttataa tttacatgga tctcgttttg tgattgattg
    83941 aaatcctcaa tgatttcttc gatagcttct tttcgtgcac cggatcccca aaaggaccag
    84001 aaatcaatat tttttcttcc atcacttgtt ttttcagaag aatttgctgc acttgaactg
    84061 gcatcgcttg cattacttga tccgcatcct cctaataaaa acaatgctga acttgccagc
    84121 aaccctgtaa acaataattt tttcatattt tacctccaaa ttttaatgta accgatgccg
    84181 gttttaatat aacgatatca ttttgttctg aaaataacaa tttataaggt atgattctaa
    84241 aaaaattatt aatgatacca atactttata taattcgcga gcgctttctt tgaatttttt
    84301 aatctttcgt agcagaatga gaatgtatta aaaatagatt aggaggaatt ttgatgttta
    84361 gacaccagaa agaattgcag tttgaagcaa aaccagatcg tccgaatcca ttaatcgcga
    84421 aatatctgca ggagctgatc ggcggccaat atggcgagat gagtgtagct atgcagtacc
    84481 tgttccaagg ctggagctgc cgaggagaag aaaaatataa agatatgctg atggacattg
    84541 caacagaaga aatcggccac gtggaaatgt tggcgacaat ggttgctcgt ttattagagg
    84601 gtgcgcctgt tgaagatcaa gaagcagcga tgcaaaaaga tccaacaatc ggtgccatta
    84661 tctctggaat gaatccacag cacgcgatcg tagctggctt aggacctcgt cctgctgaca
    84721 gcgtgggcaa tccatggagc ggtgcctata tcattgcgag tggcaacttg ttagcagact
    84781 ttagagctaa tttaaatgcc gaatcacaag gaagacttca agtagcacgt atttacgaaa
    84841 tgatcgatga tcgtggcgta aaagatatgc tgtctgttct ccttgcaaga gatagctatc
    84901 atcaaaatct atgggaatgt gcagtgaaag aattagaaga aaaagaaggt tcaatcttag
    84961 tcccaagtac tttcccgcgt gacaaagaac gaaaagacat tgcttatgac ttctataact
    85021 tctcagaggg agaccaaagt agtgaaggtt cttgggctag tggcaaagca ctggatggcg
    85081 aaggcgaata tcaatggttg aaagaaccta agatcgaagg cgctgcacca aaattagaac
    85141 cagtaacacc aaaaatgtat gggacacctc cattcaagaa ataaatatct acccgtagaa
    85201 acacccgttt tttgttccac acgctttgtg agcaaaactg actaaagtca ttaatcataa
    85261 ccacccttca aaagggtggt tttctctaga gctataagct caaatcaccg gccagcgcct
    85321 aaagacgctg gctttcatat tttatgttca agccatattg cctttgccag ttttgcccac
    85381 ctcttaaaag gtttatgtac tactccttag cccttaaaag gatcgtctta ctctcgtaca
    85441 ctcagcttat ctaacgcact atcatgtttt tcttgttctt gaatgtactt tttgatggtc
    85501 gcttcatttt gtcctacttt tgtcacatag tatccttcca cccaaaagtg tcgataccca
    85561 aatttatatt ttagatttgc acaatctctt gatgatctcc tgaatattgg ctcgatattg
    85621 attataaatt atttttcttc tatactttgg tgtgaataca atgtggtatt tacacatcta
    85681 ctttgtacgg gctaaactat ttccctttat tgctccaccc gcatagcaag tggttttgta
    85741 tttcaatcgc tcggcgcgct caattaggtc taaagacaat aaatctaaaa acccgctgct
    85801 tcactgacag aaacaacggg ttttcagaaa aaaatgaaat gaaaaagatc tcttacggca
    85861 atctatttta tttttttgat tttttataaa tggaaaatgc ttcaagaagt ccaagaaata
    85921 aagccgtata aaaacaagaa cctatgaaat ctttatttat tagatattca acagaaatcc
    85981 cgataacact agccaacaat atatttatca gaagtgtaaa ataaggatgc tttttataga
    86041 atagaactag tgttgttttc atagactctc ctttcttcat atttccaatt aatcacaaat
    86101 tcacggcatt actagaaaaa ttaaaggggc gcagaagtgg aaaaatactc ttcgactttc
    86161 cctacaaacc aggccatctt gtgtttaata actataccaa atctaaggta cctctaaatc
    86221 taaattccat ttgtggcggt gacctccaat ttttaactct tctatctccc atccagtata
    86281 cataaccttg atacttcgac cacttatata tcgaacacac aaatacctat ccattgcagg
    86341 agtactacct aacttagttg ctacttgcat ctaaataaca gctgaaaaga taggacttac
    86401 tcttagtaaa gtatctgaac tattaatttt taaactatca tttttatcct caactacatg
    86461 cacatctgtt gcaacttcac tttctgtctc atccagataa atgattaagg aatcgggaat
    86521 tgcaatatct tcagctgacg ctggaatagt tgagctaaat tagtcatcat atctttatta
    86581 taaaataacc aacagcaaaa aatacaatga aaaacaaact tggaactaat gtatcattaa
    86641 taaatgttga aaaattcagc aactcattac tgtatgattt tagcagccca accaacatat
    86701 accctataaa agctaataag atggttagga atcctttaga atttttactc attcatagac
    86761 acttccttaa ataactttta ttatagaagg tattgtaaat aataatattg acaaaaagtg
    86821 actcaaaata aaaaaaaact tacattatac tggaatgaac tgtattgata gtgtacctaa
    86881 aagctctact gacataagat cgtgtaatcg gtaaagtaat tttattaatt atacgggatg
    86941 taatcaatta gagaataaac taatcataaa aggtactttt acattcataa ttgtcgcttt
    87001 gagattctac tttggttcac tatctgaccc aattgcacat tttcgatcat tacaagtatt
    87061 ggtgtcgtta gaacaactaa ataaaaacta gcggtagatt tttcagaatc tatgctaatt
    87121 tctgtatgga tgttccagtg atggcaaatt tctcttttca ttgtttttct tgtcgcatga
    87181 tatgcctttt tgtgttattc agttaaacta tagaaattct ttcctagaca gatcttgatc
    87241 ccaaatttta cgtttttgag catcgatata gtttaaaatg acattactca tatctaaaga
    87301 gtttagattt tttaggacta aaactgtcag ttgttctttt tcttctttct gttaaagtat
    87361 tgtcgcgact tttcgtatac gttaagatat gtcgtgaaaa aacaagtttt gtgacacaaa
    87421 aaaacgaatg acttgaggaa atcacctcaa tcattcgttt aaaatgctat atattcttta
    87481 gtttaagata cggaaattaa tgccatcgac cacactagta gaatgaacga catttacttg
    87541 gccttttttt aatttcgtta tgtttagcat ataaaaatat tatagagttt acttacaatg
    87601 cttaaaacat atactgtata atctgatcaa ttttagccat gtcttgcaat ggtaagtttt
    87661 ctattttttt gagttttcgt tccttaaaat caagagattt taattgtgta ataattactt
    87721 gtccttttat atctagctct tcaggtaatg agtaacgtgt cggtaaattc tttatagtgg
    87781 aagtaattgg acatatgacc gaaaacattg ttttacggtt aaattcataa cgagagacga
    87841 ctagtcctgg tcgtcttttt tgaatttctt ttcctacgga gggatcaaaa tcaatccata
    87901 caatatcacc ttttttagga atataaattc tttcttctga cactataaaa tttctctccc
    87961 ttcaggagtt aaatcttccc attcgtcttt ctcataatac tcggcctctt ccccaccact
    88021 aaatggatct tcaatttttg gaactaacgt aattgttcca tcatcagaat acacaacgat
    88081 atattcttgg ttttctgaag gtttctttcc gttatcagaa ggtaaagtta ccactacaga
    88141 acttccttgt aatctagatt ttgtaacaag cattatcatc actcccttaa taaaagtata
    88201 ctatataaca ctaagtaacg caaaattccc ctttgtaaac tatctagaaa attgttttgt
    88261 ttaaagtata tcttattgga tataaataga aataaattgt agccagttca ttttttcttt
    88321 aactaaaaaa ataatccaag aaacattgaa cctatggatc caaaagctac ccaaatacta
    88381 tagctaaccc cccgctacct tcaattttgc agataaaacg ctttgggaga aaatttcaaa
    88441 gacaacaggc catcctatca tgcccgatta taaacaaaaa gctggctatt ccttttgctc
    88501 tgacaaattt caattgggaa agttcacgaa actagcaggt gaagaagttt caactgttcg
    88561 gatcaaagaa tgcccgcttc aaatagaaac attggttcaa cgaatttcaa ctagacaaga
    88621 ctttgctatt gtagaacgtg agatcgtagc tatttttgta gaagaaggga ttttacatga
    88681 tccaactcat atcaatgtgg ataaatggca acctcttatc tataaattca gagaatatac
    88741 aactgccaac cagtcgttaa ctttgaattt tagattccaa gaattcaaag agtcataatg
    88801 ataaacatcg ttaggtataa ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag
    88861 ctatacatta gaaaggtcga ctgtgaccct atagatgcag tatatgcagc ttatgagcat
    88921 ttcttctgtt ctctttgttt ttgggatctg tgctgaagtc tttttcgttt tttgccgctc
    88981 tttctttgaa aaatcgatta tgttatacct tctccattac taattcaggc atctgctgag
    89041 taatgatttt tcgcgcaaaa gaaatatctg ttacccaagg ttcgatttgt tcttcagtca
    89101 agacaagcgg cattcggtca tggattggtg cgactgtgcg gttaggttca gtagtcatta
    89161 tgattgattc tgccattttt tcatcctgat ggctacgata aaaaccgcca atatacacta
    89221 ttttttcctt atttgaaaac ataaatttgt ctttttcttc attccactca ttgggaaaac
    89281 acaacgattt tgcaaaaatg gttgatgaaa ggtctttttt tcttctactg tctctgcacg
    89341 ggcattaatc atcaattgtc cttttttaaa tccggtaaat ccccacttca tgatttccgg
    89401 agtgaggatg ttttcttcct cttttcttaa cgtcacaaca agatttgacg gaaaaacttc
    89461 tccagctgct aattctgctg cctgcttcgg ttgtttcgtc tgggcttctc gataataatt
    89521 ctgaaggagc tctgactcta gatcaaaaaa ataacgacca cacatcctaa tccctcccaa
    89581 tctttttttc tatcatacac tgcaacaaga agttcgcacc aacaaaacac tttcaatttt
    89641 tgtagaacta aaaaagttgt gacaagtgac aaactctcca gtgaatggta ttctcctgcc
    89701 aactcctcgg tcacaagtca caatattcaa caaacatgag aagctgcttt ttgaaattgt
    89761 tccttgtgac tcggagtgaa acggcaggct tacgacctct gggtaaacgg tgttcaaaag
    89821 ccagtttctc ggtattaagc caaatttatg caaaaatgta gaaagctatt ttcacaaaat
    89881 ttttcttaat actcgaaact aagcgacttt ttcacaacct cttccttaaa cggtgttcaa
    89941 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tatgagcagc tatttttatt
    90001 tggctgttct tattacttga tgcagggcag ctttttcaca acctctccac taaacgatgt
    90061 tcaatcagct aaccttcggt attagctcaa aaaacggcaa aatatgagga actattttgc
    90121 cgtttgtttc tctaatactc aggtcaaagc gctgatttca caacctctaa tacacggtgt
    90181 tccagaagta gcttcttcga aaaataagcc gaaatttcac aaaaatttga gaagcaattt
    90241 tcgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc taattattaa
    90301 agaacctttt gcgaagttaa caatctttct ttgaccaatt gaaaattctg cctaagtagt
    90361 gatagatcct gtgtgacttt caacaataag atacttccct ggatttcagc aatcaacgct
    90421 ttggcttgac ggtctgcttc ttcatcggac agtttttctt cagaaagtgc caggatattt
    90481 tgtttcgtat acttgaccca ttgattgact aattctagta gcaacagacg gtattcttca
    90541 tccactgtac tcaactcaat aatcaaatta cctacaggac agccatgata agtgatctgt
    90601 gtctcatgat cagcgaaaat ccagtccaac atttcttcta atgcttcttc tggctgtttt
    90661 ccagcattta agatgtcttc gaacaattct gtctgccata cgtccatatg cgcatggatc
    90721 accgctagac aaacttcttt ttttgaagaa aagtaataat aaaattgacc ttttcctgta
    90781 tcagaagctg ctagaatatc tcggattgac gtttcatgat agcctttttt ataaataaga
    90841 tctttggtcg cttccaagat cttttccttt gttttcaatg atattctcct ttttcatttc
    90901 tcatagtcct atattataca gtaaattcat cattttttct tcttaatcgt ttaaaaaaga
    90961 ctgtgccaaa ttatctgaca cagccctcac tataaaactg ttctcatata gctagatgtt
    91021 cattgattca agaactgcga ggacaaaagc aattcctatc ttatgatagt tgctctaata
    91081 cttcctctgt tgtcatcact tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca
    91141 ttgcttcttg gccaggagca ccaattgcat ctgtcgctac cacaacattg aatccactct
    91201 ctaccaattc acgcatatgg gaatcgctac acaagtttcc gttcattcca ccaagaatta
    91261 ctgtgtcgat tccatttttt ctcaattgga gcgccaaatc attgctttct ggtccaaaga
    91321 ttttatgagg agagctgatg atcgtatttt catccaaata aggtttcaat tcttcgataa
    91381 aatcggctcc tgaaccttct tccactgatt catattgact ttttctagca aacatctgct
    91441 gctcaagcat catatgttct cctgcaccgc caaattgcca tttatggtca tgtgggtaaa
    91501 aataatgagg agaaataaag agtttgtatc ctttttcttt tgcttgtttt accatttcaa
    91561 tcatattttc gatcgtattg tatttttcta agatatcttt tgtcaaacca aagccaccgc
    91621 ctgctggttt caagaactcg acttgcgggt cagtgagaac tactgctgta tttttattat
    91681 tgaacatggt ggattctcca ttcgttattt attttaatac atcatttaga gcttcactca
    91741 ttgtcggatg agaatagatt tgatctctca ataacgtata aggaagtttt ccattcatag
    91801 ctagcgaaat caagttgatg acttcatgag aatcttccgc atagatactt gcccctagaa
    91861 tcaagtcagt ttcagggtcg actaaaactt tgaatacacc tttaggatct tctaatactt
    91921 gtgctttagg gacaccgctt gtcatatact tgaataattt gtaattgacg ccttgtgctt
    91981 tggcttgttt ttctgttaaa cctacattgg ataaagtcgg agtgataaat acactgtaag
    92041 gcacagcttt ccggttattc gttgttcgtt tattctcgcc cttcaactga tccataatga
    92101 ttcgataatc atctagagag atataagtga actgcaatcc gcctttgacg tctccaatcg
    92161 cccaaatgtt gtctgcatct gtacgaaggt attcatccac agcgattgct ccgcgatctg
    92221 ttagtttaac atctgtattt tctaatccaa gtgatgctgt acttggtttt cttccagttg
    92281 cagccaaaac ttttgacgct tggattgtta cttcttggcc atcttctgta aaggtgacgg
    92341 cagctgttga ttcttggtct gctacttgat ctacagatac acctagatgg aattcgattc
    92401 ccgcatttgt catgtcttct aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa
    92461 attcagaatg ggcatcaaga acgacaactt tagatccgta ttcattgaac attgatgcaa
    92521 attccaagcc aatatatcca gccccgatga tcactaattt ttccggtaat tgttcctgat
    92581 ccatcgcttg cgtagaatca atcaagtagc gacttgtatt caatcctttg attggtaaaa
    92641 tgattggttc agaaccagta ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac
    92701 cattattcgt cacttcgatt tgatggttag aaagaaaacg tgctgtaccg tccatcactg
    92761 tcccagttgc ctcatcgctg atcatatgat aatttttggc gcgaagcatg cccgtcaatt
    92821 tttctttccg agcaacagcc tctgtaaagt cgattcctct ttctccattg aaaatcaatg
    92881 atttagaagg aatacagccg atgttgatac atgttccgcc atacatacgt gttgactttt
    92941 caacgactaa aaccgattca ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct
    93001 ttccaaaacc gatcacaata ttttgatatt tttccatcat ttttccctcg cttctttttt
    93061 acctaccgat tggtacaaaa atatgataac cgataattgt ctattctcca aatcatctgc
    93121 tttatttgtc aaaaaaaacc agacaaaaag cggtcctttc acgtttttag tctggttcga
    93181 tttcctttat tcttctaaac aatcgttact tctacatcga tatttcctct agttgctttg
    93241 gagtaagggc agaattcatg cgcatcttct gcaatttttt gggcttcttc ttcgctgatg
    93301 ccatcgatat gcacttcgaa tactacaccg atctgatagc cgccatcatc taaattataa
    93361 agagagacac gtgcttttac tgtggactct gctgtcattc ctgcttcttt gatcatatgt
    93421 tgtaccgccc cattgaaaca agaagcataa cctgctgcaa ataattgttc tggatttgtt
    93481 ccttctgcat ggattcctgg aggagtgatt ttcatatgca tcgagccatt tggttcctcg
    93541 acttctccat tgcgcccgcc atggttgatc attgctgttt cgtatgcttt tttcattgta
    93601 ctgctccttt cgattgacca tttgctactt ggctataatt atagtgtatg acaagtaagg
    93661 cgctttctac aaaaattctg cttattcgaa taccagaatg ccgtcttcta ctatttttcc
    93721 aaaaaacaaa aaaatactac tcgtgaacaa cagcgtcata tttgttccaa aataaatagc
    93781 aatcttttct acataatctt ttatatgatt gattttaaga tacatatata ccagaaagtt
    93841 gaccccataa accaatactg ttaaaaaaat aaccatattc gttaccattt tttcctcctt
    93901 ttgctggtct ccctaccagc actcgattta accataccac tttttttgcc gtccaagcaa
    93961 ctagcctttc aaaaagactg gtttattctg ctgttaatga ttcaagatca gaaaaatgtc
    94021 cgaataattt tgctaatttt actaacgcca acttgttctt tccgaattca tcattttcta
    94081 tctgtaatac tagtaacggc tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt
    94141 atggctcttc tagatcatat cgaatacctt cttcattttc cgggtcgaag ttcatccctt
    94201 tttcttcttc caacagtcgc ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt
    94261 catcgctgaa caattttaat cggatttctt gtacttctac gggctgtttc aactctttga
    94321 tttgttcatc taatgtgata ccttttcttt ttaattctgg caaaagcatc aggatctttg
    94381 cgatgacata tgcaccatca tccagaaaat agttttcctt gaatgcagcg tgtccgcttg
    94441 tttcgatggc tagctgtgta tctttcccaa gacggttaag ttctaatgct ttattgatta
    94501 catttcgata gccggaaata taacgaactt ggatgcctcc tttttcttca atgaatcttt
    94561 gtagatgaga agaagtaggg gaattcgtca cgattcttgt tcctggatgc tcttttaata
    94621 cgattgtact taatactgcg atcaaattat ttcgattgat cactgttcca gaagcactga
    94681 caactgcaga acgatccaca tctgtatcga aaatgatccc aagatctgct tcatttgcta
    94741 aaacagcctg cttgatactt tccatcgctt ctttattatc aggatttggg atatgattag
    94801 gaaatcggcc atctggttcc aaaaattggg aacctgttga atccgcacct aagctattca
    94861 atactttttc agcaaagaat ccaccagcac catttccggc atcaacaatg attttccaac
    94921 catttagtgg tttgctttct agtgttccaa tccccttttt aatttttgtg actaaatctt
    94981 gcgcataagg tgtcaaaagg tctgcttttt ctacgcttcc agtttgttcg ctttttattt
    95041 tttgctgctg tgataggata aaagcaatat cttctttttc tgctcctcct tctgaggtaa
    95101 agaattttat tccattataa taatagggaa gatggctagc agtcagcata accgcagcat
    95161 cgcacgagaa ctgttcaaat tgagtggaca taaacatagc aggcgtagta gctaattcga
    95221 aatcgatgac atgtatccct tgttctttca gactttggat caacgcctct ttcagtgctg
    95281 gtccgcttat cctactgtca tgaccaatcc caatcgtcca ttttttattt ggatcggttg
    95341 atttcttctt tttctttatc cagtttgcta gtccccagcc gatctttttt accatgtctg
    95401 tcgtcaagtt tacttcatat ccttcaactg gtaatgcgat tcctcgaata tccgatccat
    95461 tttgcagcgc tttcatatct ttcatataaa agtcctcctc atttattccc tcattttttc
    95521 cagcttttct gcaaatcgct gtgcttcttc ttctgagcgg caaataataa tgaatgtatc
    95581 tacaccggcc atcgttccga caacttcagg gtaagccact tcatctagcc aattcgttac
    95641 cacatcggca ccatttcgtt cagtcaatac gataaccatg aactgaacag actggatacg
    95701 caaaacctcg cgtctaattg ctgtacgcaa acgttcttca tttaaagaaa cagatggctg
    95761 gttaaataat gtatagcgta ctattttgtt ttcattttga ctttttacta acttcatttc
    95821 tcgaatgtct cgagaaatcg ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc
    95881 aagcagctct tcctgtgtcc caataggttg ttctgtaatg atctggcgga tcagtgcttg
    95941 tcgctgtttc tttttcatat tagacacctc tcaatgttga ttatagcaaa agataagtaa
    96001 tatttcttca tattttggta ttttttactt ttattttttg ttttcattca ggttgctaac
    96061 ctttttctat tttaacacgc aaaatcgtct tcattttttc aggtgctgat tttcttggat
    96121 cgctgatgta aatctctttg tgttctttag aagctctttc atagccttct tttgcgatga
    96181 atgcttctaa tttctcaaac gttgctggtt cttcggcata gggcccgacg tgtaagattt
    96241 gggcacaaag accttcttcc atctttttga atactacttg ttctttcaag tcttccggaa
    96301 gtttgctaga acgctgaatg gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc
    96361 ggatcatcaa ttgataagaa aaatgttctt ttttcatcac tggttcatgc aaatactttt
    96421 cttgcagtcc ccattgtcct tccagtggat agacagtata catctgataa tcaggaatca
    96481 gccaattttt tttaggcgac atgcgtattg catagctgac tgcatataga caggctactc
    96541 ttcgtttaaa gtcttcctga ttcgggtcgc cgatccctct gatgctaaag aatgattttt
    96601 taggaacctc tagtatttgc gggctttttt tcatactata gctcttgtct ttacgccatt
    96661 caattttttc catttttctt cctccgcgaa attccattta gttatttatt atcatacctc
    96721 tttttgagtg acttggctaa tcgtgttgac actatttttc agtttgtgct agaataagtg
    96781 aagtaaataa atcgtacaga taacacgttt cggcgtgtcg agagagaggc ggtttctatt
    96841 tttataatag aaatcactct ctttttttac gaaatttttt agaggtgatg taaatgacaa
    96901 aacaaaaaca gctgctttta gtacctgcag taattgcaac agggatgatg tcttttgcgg
    96961 gcgtattgat cgagacggcc atgaatgtaa ctttcccaac tcttatcaga cagtttgatt
    97021 taacgactgc acaagtccaa tgggtaacaa cgatttatct tttgatgatt tcgatcattg
    97081 ttccgctgtc tacttatttg aatcgcaatt ttagtctcaa aaaactcttt ttagcttcaa
    97141 atctgctttt cttggcaggt ataatgatcg atttcttctc tcctaccttc atggtcctat
    97201 tgtttggtcg attgctccaa ggtgcagcga caggtatcgc tcttccgttg atgttccata
    97261 ttatcttgac atttgccccc ctcaatcgac gaggcgcgat gatgggtgtc ggtactttga
    97321 caacggccat tgctccagca attggcccca cttatggagg cattatgact tcacatttta
    97381 catggaatca tatcttcctg tttcttgtgc ccgttttgat tctttctttg attatcggct
    97441 ggtttgctat tcccgagatg gcagtacaaa aaagtggtta tttggattgg ataagcgttt
    97501 taggaatttg tcttttgttt agtggaagtc taacattttt gagtacgttg ggaacagttt
    97561 ccagctggat tgctttaatc atcggcggta ttggctggtt ccttttttac tatcgaagta
    97621 aaaaagtgga gcatccactg atccgactgt ctattctttc aaataaaaca ttccgcttgt
    97681 ttttgattgg cttcttagtt tatcagtttt tattacttgg tgtatctttt gtcttgccga
    97741 atttccttca gatcgttcaa ggaagtagtc cttttgtcgc tggattagcg atgcttcccg
    97801 gcgcagcggt tggtgctttg ctttctcctt tttccgggaa aatgctggat caatatggtc
    97861 cgaagaagcc aatttttgct gggctgattc tttctttgat tggttggcta gcattattcc
    97921 tactcatagg acacgcttca gtgggtgtat tgattgcttg tcatgtgttt tatatgatcg
    97981 gtatcggatt atcttacagc aatatgatga ccaccggaat gaatgcactg aatgaagaac
    98041 tacaaggaga cgggaacgca atgttcaata ccttgcagca gttttctggc gctgtggcta
    98101 cttcattagt agcggtcatt atcaattacg tccagcatca tacttcccat aactatgaag
    98161 tgtctactac attaggatca aaagcagcat taggcgtctt gttgctgttg cttctcgtaa
    98221 gctttgctcg attcgcctat tatctgttct ttgctaaaaa agcgtagatt ccatatacgg
    98281 caggtgttgc atctgccgtt tttttgtgtg aaaatggttg tttgtaaaag gaggcttttt
    98341 tatggaaaaa attgccatta tcggtggcgg gatcattggt atgaccctag ccagttactt
    98401 agatacatca aaattcaatg ttgctttatt tgatgaaggg acaggacagg caactaaagc
    98461 tagcgctggg attatctccc cttggttgtc gaaacgcaga aacaaacaat ggtatcgtct
    98521 ggctaaagac ggcgctgctt ttttccctaa acttataaaa gatttccaac ttgatcaaac
    98581 gatttacgca caatcaggga cacttttgct tcgacctgaa aaagatttag ctgaattggc
    98641 tgttcttgcc gagaaacgaa aagaagaagc gccagaaatt ggaaacatcg aatggctttc
    98701 acctgaacag acatctcaag cacttccgtt attgaaacca gcagtttcac tgcgtatcag
    98761 tggtggtggt cgtctggatg gaaaagcata tttagaacat cttggtcagc gtttagcaca
    98821 aaaacaaatg gagcagatcc aggcaaaagt cactttgcat aagaagagcg attcttggct
    98881 catcaaggga ccgtttggag aatacacagc tgatcgtgta attttgacac ctggcccggc
    98941 acttaagcct ttattacaag aattaggcta tgctgcagat atacgtccgc aaaaagggca
    99001 gctcttagca tttcagacat cttataagat gagtcaagac tggcctgttg ctatgcttga
    99061 cggagaagct gatttcattc ctttcatgga tggaaagatc cttttaggtg ctacccatga
    99121 aaacgatcaa ggctgggatt tggctcctac tagcgaagct tataagggat tgactaagag
    99181 tacagaacag ttcttgactg atccagatca gataaaaaac tggccatacg agttccgtgt
    99241 aggtacccgt gcttatacgt cagatttttc cccatttttc ggcgtactgc cagatgatcc
    99301 aagcttactg gctgctagcg gtctaggctc ttctggcttg accacaggtc cttatatcgg
    99361 ctatctatta gccaacttct taaatactgg tcattggcct acggaagatt atcaaaagga
    99421 catctccacc tatattacga aaaatccatc atagaaaaac agctttttca agtaaggatc
    99481 ccgagcgata ttgcgcatgg attacttctt gaaaaagctg ttattttagt tcaatttctg
    99541 aatcaaattc tccaaacttt cttttgcttc atctggcaag agatcttttc ctatctgagc
    99601 ttcaatgaat cgtaaacgaa tatcaagtcg ttgtttcacc agatttttat aggacgtatc
    99661 ctcaaaagaa acaggaaaat ctggtatagg taaatagtgg atgtcttcaa atggaccaaa
    99721 cgacttgaat tctgccgttt gttgcacgat tctttcaacg attgacaatg tcgtttcagg
    99781 tttgattttt ttatcatcga aatatccagt attcaggaca tagcaggctg tttgctgttt
    99841 caaaaacaac tctcgaaaag cttgatagtc ttccctaaga ggatagacac ggaaaggatt
    99901 agcaaatggt tcaatgacta gctcatctag ctgtcttttt gtagtgatat tttccgcgtc
    99961 tgatcgtttt gttgctaatg ttgcaccaaa agacgctgct aaaactgggt cattgatctt
   100021 gataattggc ggaagcgaat catctttcat gatccaaaaa acagcatcga tcttttcgct
   100081 aagatgatcg actcggtcgg gtgtcgcata acgtgatttg actgtccgcc catttccgtt
   100141 tcgtatatct cctgttacta ggactttttc tcctttactt gtacatgtca cgcccacatt
   100201 ctgacaagta aggaaagaag aaatggccgg atcatcagac ggatagtctt gtgttttatc
   100261 aaagtaagaa ggttccaagg cagtagcaaa accatttttt cgagaaataa cgaaagcatc
   100321 gtcatgcaag atcgaaacag agtgaccttc cgtatgtttt gctaaggtaa tcgttgattt
   100381 tccagaaccg gacaacccaa atacagccat cgtataggtc tggtcattac tagcatattg
   100441 tttcatccca ccgtggcagg caataaagcc attgcgattt cccaatgccc aagcaagcgt
   100501 caaagtcgct ttttttaatt ctccaaagta acgtaatcct agcacaaccg ctgtattatg
   100561 gagagcatca aacaaaatga gtccatttgg aaatgtttca tgtgtccatt cgggatcaca
   100621 aaagatataa agatctccct catcaaagga aacagacttt tgataagtct ctaagatctt
   100681 cgaattcgct ggctgaaaat tcagcaaata agaatacaaa ttgttctcaa atccttctgg
   100741 aatcagcaaa tgactttgca cagaaaattc ttcagatagg ccaacgatta cttttgtatg
   100801 gtaaaactgg cgcttgcgac tttgatacac agcttctctt aaaattttct cgtatttgct
   100861 ttgttccttg tctaagtcct caaagatccg ccgagcactt gctgttcttc ccacaatgct
   100921 tccatcattg aatactagtg tcctaacatc agctggtaaa tctagttctt cagcatgtga
   100981 gattgttaaa tctgtgatga tcgttcctgg actccctttt gctagttgat aagctgtctt
   101041 cctatcaaaa acttcatgaa cattattacc gtaaaatgtc gtttctacaa tcgatcgaat
   101101 actggataac agtggatttc cacttgtgat ttcgtttaat tcgagactct cttttgtact
   101161 catggctcct cctcattccc taaacaaaaa aacgttttct ttattataca ttattcgagt
   101221 ttttatttgt actgctgcgc tgtgggaagc aaacgagtta tttttcacac aaaaaaaccg
   101281 agaacttgaa taaacaagtt tctcggtttc atcattttcc ttttatcggc ttagtaccag
   101341 ccgtttgcta accagaatgt tttagcagca tcccatgaac cataacgaga tgttacatat
   101401 tgttctgcta cacgttcttg attggcagct gaatagtcgc cgtttaagta tgaagcatct
   101461 aattgataac ggccgatgta acgtccgtta gtagctgtgt atgaaccgcc tgattctttt
   101521 tgtgcgatcc attcttttgc agagcttgaa gttggcgctg ttgcagcagc tggggcagca
   101581 ggagctactt caactgtttc aacaggtgca acgtatgtat gttcttgcgt tgctgtttca
   101641 gttgtagatg ctgtattttc tgttgttttg ttttctgttg ttgctgaaga atcatttgaa
   101701 gttgggattg ttaattgttc accaacataa atgcggttga tgtttgcgat cgaatttttt
   101761 tcagcaattg catcgatcat tgagttgtct cctgcaaatt tttgtgagat cttagataat
   101821 gaatcacctg attttactgt ataaacttca tcagcgtgag catttgtagt tcctacaaac
   101881 attgcagtag caccagcagc aaaagttgta cctaaaacaa ttttcttaaa tgaattcata
   101941 ttaaactcct ttttttctcc gttttttatt ctttcgacgc tattaacttt atcatttaga
   102001 aatatttcat aggtaaaaga aacatgacat ttaatgacaa aataacgaat tatttaatat
   102061 ttgtaacatt taaacaaata tttttttgat acaaaaccat aaaagccttg ttgtataagc
   102121 aaagtaatcg tttttctatg ttttttttat ttttgaatga aaaacgcaga ttctgtaaca
   102181 ttcactgcaa taatccataa aaaaaagcaa aaaaattttt gatttttatc aaattctctt
   102241 aaaaaaatgt aaaaaataca aaaaaaccag taattgttac aacaattact ggacaaaaac
   102301 tttgaataat gttaactatt tttttatttt aactttctcc gcaataattt ctgggcatgt
   102361 tccaattcgt ttataacgac ttcttctgtt tctttagcta atatttcatc taatacatca
   102421 agccattttt ccggttcttt tgttcctaga cgtccaatag cccaagctgc tgttcctctg
   102481 atgacagggc ggacatctgt taaacattct gaaatctcag gcaatgccgt tcgatcacct
   102541 agattagcta aagcaatcaa tgcgtttctc tgcaaaggtt tcttcccacg ccatgaacca
   102601 gctaaatgcc caaattgctg tttgaagtct ttattagaca tcgaaagcat tggctttaat
   102661 tttggatata tttcgtctac ttttggttcc atctcttcat gaaaatgaaa atcttttcct
   102721 tgattgtaag ggcagactaa ctggcagata tcacatccat aaatgacatt tcgcattttt
   102781 ttacgatatt cttccggcat catccctttt gtctgagttt gataagacaa acatcgctgg
   102841 gcattcattc ttccgtcacc aagcaatgct tttgtcggac aagcagtcac gcagcgcata
   102901 cagtcaccgc aaccaaattc tcctggttta tcaggctcaa atacaatatt agtaacgatc
   102961 tcaccaagat agacaaatga accgaactct tcagtgatca acaatccgtt tcgtccaata
   103021 aatcctaaac cagctcgctg tgctacagcg acatcgatca gttctccagt atctacttgc
   103081 ggagctagac gccattcctc ttctttttgc catttttctg ctcttgtttg gatgaattcg
   103141 atcaatcggt tcaaacggtc tctgagtata tcatggtaat cgatccccca agaagcacga
   103201 gcaaactgcc cgcgtttttc atccctaggc acttcttcat ggatcctagt aggatacgca
   103261 agtgcaatgg aaatgatcga tttcggctga tcaaatgtca tttctggata aagacgctca
   103321 tcgatatttg gatgttcaaa gccagaagta tggccagctg ctttttgttc ttccaacgat
   103381 tcttttaatg aatcaaaagg ttccgccgtg gtgaacccga ttttgtcaat tcctaatcgt
   103441 ttgctttctt gtatgatttc ttcttttaat gtcatggtct tcctcgcttg ctgttaacgg
   103501 ctgtataacc cataatatag tttttctttt ttcagctgga caaactggat ctgctgatcg
   103561 gcattcttct tttcttccat ccattttttt cttgcagcaa atacttccca ataatttgtt
   103621 gaaattaatt ttcttttgtt atctaatgca ttaaaaaaat tcaatgaaac tggttttgta
   103681 cttaacagtt catggagcct tacctcttcc catggcgaaa actcagacag atcgcgggaa
   103741 tacaatactt cttcatagag atttttttgc tgtgtgtacg tgaatgtttg cgggattttc
   103801 ccaggcctag caatttctac tagacgatta taaaacatat tcattaattt gctgttggca
   103861 ataaattgac ttttataata ggccgactgg atctttttga ttactccttc tgctttgatg
   103921 actgaaaata atgcaggcca tgctttgacg gttatttcgt cgttttgttt aactaatacg
   103981 ccaggtgtga agccgactgg agaaaggaac acaaaataac cgataccggt attttcatct
   104041 aaaggctgaa attcatcaaa caaccatttg cctatgtaca gctcttcatc tggttctgtt
   104101 gtctcatttt gatttgctat gaataattta gctaattctg cttcaagaaa ttgaaggtct
   104161 tgatccttgt cggtattttc ctgctggctg atcaatcgaa agacttcttc tttaatcgta
   104221 tatttatctt tacgtgtaaa attcatagcc acaccttcct tccttactct aactataacg
   104281 gaatttcttc aaaaaaggta tctgtacgac gaaaaacagc ataatttttt ttcatatctc
   104341 ttataaaaaa tgcaaggtct gctcctcaag ctagaccttg cacttttcag ctttcttttg
   104401 tttgtgacaa accttcatgg atcgtttcaa tattccattt catcatctga tagtaagaat
   104461 ctccttgttc tccttctttt gctatggaat cagtgaacag tttatcatag attttcaaac
   104521 ccgtttcttt tgctacccgt tccatgcttc ttgagtctac actggtttcc acgaataaaa
   104581 ccggtacttc ttttgctctt atctgatcaa tgatcgcttt catttgatca ggcgtacctt
   104641 gactttctgt attgatctcc catatataag ctgctggcaa atcatatgct cgtgaaaaat
   104701 acttgaatgc cccttcactt gttactaata attttttgtt ctcttcgata gaagcaaaac
   104761 tttccttcgc ttgtgtatct aattctttta gtttttccac atatgcttct gcattttttt
   104821 tatagagtgt cgcattttct gcatcttttt cagagaatat acgtgcgatt tcctccacat
   104881 attttattcc gttagatagg tctagccaag catggggatc tgcttttgta tgttcttcac
   104941 cgctagttaa ataaagaggt tctacatttt tgctaactgc aaaataatct tttccttctt
   105001 cttttttagc cgtttccatc aagttatcga accagctgtt acctgtttca agattcaaac
   105061 cgttgtataa aataacatct gcatcgcttg cctttttgat gtcttctggt agtacttcat
   105121 attcatgcgg atctgttccg actggtacga tactgtggat atctatttga tctgttccga
   105181 cctcttttgc catgtccgcc aagatcgaat tggtagccac gactgacaac ttttctttac
   105241 ttccttcatc cgcttggtca gaagcctgct ttccgcaacc ggctaatacc aagaaactaa
   105301 ctgccaagat taaaaagagt gatttttttg ttttcatcta tctgcttcct ttctgaaata
   105361 aaattccttt tgttggagaa aataaaaaag caaggataaa aaatgcggta catgctaaca
   105421 cgatcgtagc tcctgatggc caattgtaac tataactgaa aaacacaccg acaactgcac
   105481 ttagcatacc gattcctgca gctgtaatga tcattttcag taaatggttc gttagcaagt
   105541 aagccgtggc ggctggtgtg atcaacatgg caatcaccaa gattgttcct actgtctgta
   105601 aactgactac agccactaat gtcaaaaaga acatcaaaag ataatggatc agcgatgtgt
   105661 tcagcccata agcttttgcc attgtcggat cgaatgatgt gatcttcaat tctttataaa
   105721 agaaaaagac aaatatcaag acgattccac taacgagtgc tgtcagcaac aaatcgcttt
   105781 ccctaacagc taagacattc ccaaataaaa tatgatacaa atctgtcgca ctctgggcat
   105841 atgaaatcaa gataatccct aatgcaaaaa aggagctaaa gacaattcca atcgctgtat
   105901 catttttcaa tcggctccgc tgagtcacga aaccaatcac tgctgctgtt agcatcccaa
   105961 aagcagtggc tccaaagatg taactaaaac caaacatata agaaatggct acacctggaa
   106021 gaactgcgtg agagatagcg tctcccatca aagacatccc tcgtaaaata ataaaagaac
   106081 cgatgactcc agaagcaagt cctacaagca tggaagtgac caaagcgtat tgcaggaatt
   106141 gataattcat taatccatca ataaaggatt ggatcatttt ttctctcctc cttttactaa
   106201 atgtctgatg atctcaccat aggccaattg aaggttcttc gatgtaaaga cttcttgtac
   106261 tggaccggaa gcgatcagct gtttatttaa aagaataacc tcatcgaaat attcttctac
   106321 tttatgaaga tcatgatgga cgatcaaaat cgtttttcct gaattcttca attcctgcaa
   106381 gatgtcaaag atctttcgtt cacttaacgc atcaatccct acgaatggtt catctaaaaa
   106441 gatccattct gctccttggg ctagagctct tgcaataaaa actctctgaa gctgtccacc
   106501 cgatagttcg ctgatctgtc ttttggcata ttcttccatc cctacttttt tcaaagcttg
   106561 tcttgcacgt tctttttctt ttttcccagg tctttgtcca attcgtaaag atggatatgt
   106621 tcctaaaagt acaacgccta atacatcaat tggaaaggaa agatccaatt cacttcgctg
   106681 ttccacgtag gctatttttt tacggactga gtttaccgac tgtccagaaa aggtgacttt
   106741 accagtagta gctggtatca actctagcaa agatttcata aatgttgatt ttcctgcacc
   106801 gtttggtccg ataataccgg taattttttg tggatttatc gtcaagttga tagttttcaa
   106861 aacagttttc ccttgataag cggctgaaag gtcttgaatt acaatggccg tacgttccaa
   106921 atcttacact cctttttagg tttacctaac tttttattta aatatagttt aactaaaatg
   106981 gaaagcattt tcaagtagaa tgatgaaaaa gtttttttcg aattttcctc gcattttatg
   107041 aaaattttct gtagaatcac atcaagagtt caataaggct aacctaataa tgaaaaacat
   107101 gtgttgaaac gtttgattat tttttcttgt tgactcaaca acgaaaggag tttttgtatg
   107161 gaagaagaaa agttaactcg aagtcttagt gcccgtcata tccaaatgat cgcactaggt
   107221 ggaacgatcg gtgtcggtct gtttatgggt gcctcctcaa ccatacgttg gacagggccc
   107281 tcagtgatgg gagcctatgc gattgcagga ttctttttgt atttgattat gcgtgcttta
   107341 ggcgaaatgc tttacgttga tccttcgact ggttcttttg caaattacgc gagcgagtac
   107401 atccatcctg tggctggcta cttgaccgct tggagtaata tttttcaata tattgtcgta
   107461 ggaataagtg aagtgattgc tgtaggatct tatatgaatt attggtggcc tgatttgccg
   107521 gcaattattc ccggaatcat tgtcgtcttg tttcttatgc tggcaaatct tatttctgtc
   107581 aaggcgtttg gcgaattaga attttggttt tcgatcatca aagtcataac gatcattttg
   107641 atgatcattg caggtcttgg ggtaatctta tttggatttg gtaatcatgg tcaggcagta
   107701 gggatttcaa atctttggaa aaatggtgga ttcttcactg gaggcgtcaa aggatttttc
   107761 tttgcattat cgatcgttgt tgcttcctat caaggaatcg aactgatcgg aatgactgct
   107821 ggtgaagcag agaatcctaa aaagacgatc attgaagctg tccagtccac tatcggtcga
   107881 atcttgattt tttatattgg tgctattttt atcattgtga gtatctatcc gtggaatcaa
   107941 ttgagtgaga ttggttcacc ttttgtacaa actttttcta aagtcggcat tacatttgct
   108001 gcaggactga ttaattttgt cgtgattaca gcggcattat caggttgcaa ttcagggatt
   108061 ttcagcgcaa gtcgtatggt ctatacactt gccataaatg gaaagatgtc taaaaaattt
   108121 ctgaaactat ctcgtcacgg tgcgcctttt tatcctgtcg tagcaatctc aggtggaatc
   108181 ttaattggtc tgatcttaaa ttatcttcta ccaatgttca tcaaccagtc agaaaatatt
   108241 ttcgttttcg tatacagctc aagtattttg cctggtatgg ttccttgggt agtgattttg
   108301 atcagcgaga ttcgcttcaa aaagaagcac gcagataaaa tgcatgatca tccttttaaa
   108361 atgccactat ctccttatac gaattatgtg acacttgctt ttttagctat cgtattgatt
   108421 ttcatgttta tcaatcctga aacgagaatc tcattgatta ttggactcgt tttcttgctt
   108481 tacatgacga tccattactt tgtacgcgaa aaaagaaccg gaaaataaaa aaagaacgaa
   108541 gcttcacctt agtggaagct tcgttctttt ttattgcttt tatcaattca attttagcgt
   108601 ctcaccggga gtcaggaaat aattctccat gctcatccca ttcagcgaca agatcgtttc
   108661 tactggtacg ccagttcgtt cggctatttg atttggacct tctccttcca aaactacggt
   108721 tgtcgcagcc tgtgaagtcg cgctgttggt attagtttca gaggaatctg ttgtgtcttg
   108781 tgttgttcga gcttgcattt cagaagcttc taccgactct gctgtctcag aatcagaaga
   108841 tgttgtgtct tgtgtgcttg ttgactctgc ttgaagagag gcgctagtct gcaaataaat
   108901 atcggaaatc ttagcgacat gattcgtata attagccgat aattgattga tcaaagtatc
   108961 taagtctaca ccgtctttat tttctgctgc ctgatacgct gcacgtaatt ttctgatccc
   109021 ttcgtcggag attgcttgaa gctcacgtgc tttttggtta gcaactgctg ataaaccagc
   109081 tattccctct tgatttccct gaatttctgt ctggtattct tcaatcaatg caggcgtctt
   109141 ttcttcgatc tttttcgaat aatcatttac gattgcttga agttgctctg gcaaaccatt
   109201 tgctgttttt tcttcagaag tttgtgtctc ttttgtttta gttgatgact cacttgtttg
   109261 tttcgtctct gttttctttg tcgttgtttc cgttatggtc gtacttttcg cttctgacga
   109321 attttttcca tgaaaatata gacccgcaac tcctcctgct atgatcaaaa acacggcaac
   109381 tgctgcccca atcatgatca tccgcttacg agctgcctgt ttttgctgtc ttcttcgggt
   109441 catccgaaca ttttctcccc actcattttc atcatacatt tttttcacca ccaattttta
   109501 tgtataatag cgttatcaaa cgcttcatat tcttattgta gcaaataatt gtcgctgtgc
   109561 acatttttat ctttgttatt tataagaaaa tttcaccagt tgagatgatt ccaagattgt
   109621 ccgtcgattt ctccttgcag ctgcattgtt cgttcgtcta tctcagccat cagtttcttt
   109681 atttcatata agagcgcacg gtcttgatat tctgattttt cgcttaattc atctaattgt
   109741 tggatcagcc aatcatttgt cataatgaag ttcctttcat ttcttgcagt gtaaaggtca
   109801 agtcttcgat ctgctctttt gcctcagtca gtgcttctac gatatatgct tgtttttcag
   109861 attcttcttc ctgcattttc tgattttcct gtactctttg aataaaccag tcaatccgct
   109921 gagtcagcga tggtttgcct tccaatgaga gatactgctg ataagcaatt agcttctccc
   109981 aacgtttttc ctgggataaa tacataaatt gtgctaaaac gaatggcgga agataggtca
   110041 tatggaattt atttgcgatt cgctgatacg gcctcaaaaa ttcggaaatc gtatattctt
   110101 cttttcctcc agcttggtat tctttttccg ccacacctgt tgtcaatacg attcctagtt
   110161 ctttcccttt taatacatgt gctgctcgtt ccaagacatt atcttgccaa atttttaaat
   110221 gagcaggaga actataccag taaaacggaa actggaaaat gatccgatca tgctgggcca
   110281 agagctgtag ttcagtctct atatctattt ttccgtctgg ataacttgat tccaaatgat
   110341 gccaagtagc tggtaaacca gcagaagctt ctttgaaaaa ttgctgattt aaagattctt
   110401 cgatcgttgg atggctaatg atgataagtg tacgcatccc ttttcctcct ttttagtctt
   110461 cgctttacag tgtagcataa ccgccacaag tttcttttgc cgatgcttgt cattttaacc
   110521 agactaatca ggttgtccaa gaaactgtgg tttgtttttc caactgtttt ttcaaggtat
   110581 ccaaagcaat attcttaaaa tttttgtttt tcatacgttt acgatagttc gtagccgttt
   110641 ctccggtact ctttttgaac attcggctaa atacgactag actattgaac cctacttgat
   110701 aggcaatact ttccacggat tcatccgtca gagaaagaag aaacgcccct cgattgatcc
   110761 gtaccccgat caaatattcc ttgatactgg tacccatatg atttttgaat actcgcgaca
   110821 aatggctccg attgaccgct aaatgctggg cgatttcctc aacagacaat ttttcagcat
   110881 aatgtgcctc gatgtatttg actgtttcaa cagctaaaga ggaatgaacc ttttgtacac
   110941 caccgctgac ctttccgcca tcttttaaaa ggactgataa aaaacggtag gttaatgctg
   111001 ttaactgtaa ttcattttcc aaggtttctt ccgtatcttt catgcattct aaaataatgt
   111061 cgatatattt ttgtatgtca gaagagacca tcgtgtattg gtcttctctg aaaagcgact
   111121 gccgaatgat ttcttctgca gcactcccac caaatgaaag ccagcaatac atccacggat
   111181 cttctccatc tgataagtaa aacgtcgagt ctcctggacg aatcaagaac agatcacctt
   111241 ttttcaattg gaattgttga tttttcacat gataagatcc tttgccttcc atcacgacat
   111301 gcaggatgta atcattgcga atagcaggac caaaagaatg aaacggcatc gttttagaga
   111361 aaccacaaaa atcaaaatac aattcttttt ctacttgttg atgttccttt tttaaaaaaa
   111421 tcgattgctc cacgtctatc cctccttact cctttagtat aatgcaacaa aaagttaaat
   111481 aaaagtcaca gaaatatatt aaaaaggaag cgatttcttg ttaagtttaa gtcattaaaa
   111541 gatctttgtt attcgttgta accggtttac ttagtattat atattgaaca ggagaggaat
   111601 acagattatg aaaagcaaaa tgatccaacg tgtgtcctac gctttaggcg cttttggaca
   111661 cgacacattc tatgttacat taagcactta ttttatggta ttcgtgacaa gccagatgtt
   111721 cgcaggaaca gataaggcaa cgaatgcaaa aatgattgct acagttacaa gcttagttgt
   111781 aggtatccgc ttagttgaaa ttatttttga tcctttgatt ggtggcatca tcgataatac
   111841 tcgtacaaaa tacggtaaat tcaaaccatg gttagttatc ggcggcgttg ttagttccgt
   111901 actcttggta gcaatcttta ccaatttctt tggcttagct actcataata cgactttatt
   111961 tatcatatta tttgcaatcg ttttcatctt attggatagt ttttattcat ttaaggatat
   112021 cgctttttgg tcaatgattc cagctttgag tacggaaaca aaggaacgtg aaaaatttgc
   112081 tacgtttgct cgtttcggct cttctctagg tgcaaatggt actactctag tcgttgtccc
   112141 tatcgttact ttctttacct atcttgttac tcataaacat attgaaggcg cttcaggctg
   112201 gttctggttc ggtgtgattg ctgctgttat ttcaggcggt actgcgatta tcactgcctt
   112261 gggcacaaaa gaagtcgata ctgcgatccg tcagcaaaat gaaaaagctg ggatcaaaga
   112321 tgtgttcaaa gcagttgctc aaaatgatca gttgatgtgg cttgcccttg cttatatcgc
   112381 ttatgcgatt gccaatgcag caacaactgc cgtattattc tacttcttca aatatgtact
   112441 tggccaacca actgaatttt ggatcgttgg tctagttgct gccttacttg gtttagtagc
   112501 tgttccacta ttcccaatgc ttacacgcgt catctctcgt cgctacgttt accttggagg
   112561 gatcgcaatg atgatttctt cttacttttt ctttacgatc gcaggttcaa gtttgccaat
   112621 cgttatcatc gggctagtat tgttctactt ccctcaacaa ttgattttct tatccgcttt
   112681 gatgacgatc acagactctg ttgaatatgg tcaatggaaa aatggtatcc gtaacgaagc
   112741 tgttactcta tcaattcgcc ctttactaga taaaatcgct ggtgctttgt ctaacgggat
   112801 cgtagggttt gtcgctatcg cttctgggat gactggtaat gctactgctg ctgatatcac
   112861 tgctcatggc gtaacgactt tcaaagctta tgcattctat gctcctgctg ctttgatgat
   112921 tttctccgct attatttttg cttggaagat tacattgaca gagaaaaaac atgcacaaat
   112981 cgttgagaaa ttggaaaaca aattggctcc agctgataca atggaagatg aacttcacga
   113041 tgcagtagat ccttcccatt aagaaaggat cttgaaaatg aagattacag aaaaagattt
   113101 tggccaaggt tatcacttga taaccttgga gaacaaaaac aagctagcac tttctatctc
   113161 tgatttaggt gctagaatcg tcagtttaaa atcaaatgat cgagaattag ttttgggatt
   113221 tgacaccgct gaagaatata tcgaaaaaga tccgtatatc ggtgcttcta tcggtcgcac
   113281 cgcagggaga atcgaaaatg gccacttttc tctcaatgga aaaacttacc aattagccac
   113341 agatccaaaa actggacata atctgcatgg tggtgctcct ggatttgaat taaaaaaatg
   113401 gtcttatgtc attttgaatg gcgaaaatga agcttctgtc atttttacta ctacaagtcc
   113461 cgacggagaa catggttttc caggtacaat ggatgtggaa atccgctata ctttgacaaa
   113521 agataatatc tggcgagtga cctctcgcgg caccagtgac caagatactt tattcaatcc
   113581 gacaaatcat gtttacttca acttgacggg agatgcttct cagtcaatcg atcaacatga
   113641 gctttggctc aatagcgaag cttatgctcc tttgcgaaca gatagtattc ctataggggt
   113701 aaaagaaaat gctgcaggaa gtgctttcga ttttcaaata cctaaaaaat tagcgtccgt
   113761 ttttgctagt gatttggatc aaaaaaatct tgttgacgga atcgatcatc catttttctt
   113821 aaaagaaacc ggcttgggta aagaagccgc tcgcttgact agccccgata aaagaatcca
   113881 agtagatatt gctacagatg cttctagtgt ggttattttc actgcaaatt tcggcacaga
   113941 aacaccagaa atgcgcaacc gaaaactggc acatcacggt ggcatcacat ttgagactca
   114001 aacagctcca ggtgcagagc gcttctcagc atttggttcg attcatttaa aagccggatc
   114061 agtatttgaa acagtgacag aattcaaaat caaaacaaga aaggaataac tcatcatgga
   114121 aatcaaaaga agcttaaaca caaaatttgc cgaaacattc ggacctaaaa aaactacaca
   114181 atacttctca ccaggacgca tcaatttgat tggtgaacac acagattaca atggaggcca
   114241 tgtcttcccc gcttccatca cttatggaac gcaaggtgta gcagcacctc gagacgataa
   114301 taaaatatta gtttattcca caaactttga cgatatcggt gtcattagtt ttactttaga
   114361 tgagctagaa tatgataaaa aagcaaactg ggcaaattac gtaaaaggaa tggtccttaa
   114421 attaaaagaa gctggacact caatcgatca tgggtttgag ttattagtgg aaggaacaat
   114481 ccctaatggt gcaggacttt ccagtagcgc ttcattagaa ttattagtag gtgttgtatt
   114541 agaagatctg tttgatttaa aaacagatcg cttggaacta gtccaaacag gtaaaaaagt
   114601 agaaaatgaa ttcatcggtg tcaattcagg tatcatggat cagtttgcca tcggcttcgg
   114661 tgagctagat catgcaatct tattagatac aaatacgctg aaatacgaaa tggttccagt
   114721 gaaactagat ggttatgcaa tcgtcatcat gaatacgaat aagcggcggg aattggcaga
   114781 ttcaaaatac aatgaacgcc gtagcgaatg cgaagaagcc ttggcacgtt tgcaaaaaac
   114841 tttgcctatc tcttctttag gagacttaga tgaagaagaa tttgaatcaa ctattgacca
   114901 aatcggcgat gatacattga tacgcagagc tcgccatgcc gtttctgaaa atcagcggac
   114961 tttgaaggca aaagctgaat tagaagctgg gaacttagaa gcatttggtc aactgttaaa
   115021 tgattctcac cactctcttc gctatgatta tgaagtaact gggatcgaat tagatacact
   115081 agtagatgct gctcaaaaac aagaaggtgt cttaggtgca cgaatgacag gagctggatt
   115141 tggtggctgt gcgattgctc ttgtcaaaga agaaaatata cctgccttca aaaacaatgt
   115201 ctatgatgaa tacatgaaag ttgtcggcta tgctccggaa ttttatgttg cacacattgg
   115261 aaatgggaca acaaagatcg atccagaagc tgttcatgtt tgataaaaaa atcaacgatc
   115321 tcagctaaaa acaaatagat aaaaataacc tctcagcaat ttccaaatgt gagccttttg
   115381 ctcgtatttg aaaattgctg ttttttattg acacggaaag agaacgtgtg ttctaattgt
   115441 gttgaagagg tgattgttat gtgggcgaat caaaatccgg tatttgttta tgaaaaagaa
   115501 ccttcaagag atattttatg tattgactgc aaatcttttt acgcctccgt agagtgcgtt
   115561 gaaaaggatc ttgatcccct tacaactaaa ttagtagtca tgtcctatcc gtccgattcg
   115621 acagaaacac ggggtagcgg attaatcttg gcttccagtc ctgcagcaaa aaaagcttac
   115681 ggcatcacca atatcagccg tgccagagat cttcccttcc cctatccaag tgatttatat
   115741 attgttgccc caaggatggc ctattatatg gaaaagaaca gagaaatcaa ttctatctat
   115801 aaaaaatatg cagacgaagc gaaccatcat gtctattccg tcgatgaaag cttccttgat
   115861 gtaacaaata gcatggcact ctttggtaaa acaaatgcgt acgacatggc taaactgatc
   115921 cataaagatg tgtttgagca gaccggaatc tacacgacta taggaattgg cgataacccg
   115981 ctacttgcta aactagcctt agacaatggc tcaaaagacg gaaagcaaat gtttgctgaa
   116041 tggcgttatg aagatgtacc agaaaagtta tggaaaatct cagatatcac tgacttttgg
   116101 ggaatcggca aacgaacagc aaaacgtctg aaacaaatgg gtatacattc tgtttatgat
   116161 ttagctcacg cggattatta tcacttgaaa agcaagctag gggtcatcgg tactcagctt
   116221 tatgcccatg cttggggcat cgatcgaagt tttttgggac aagaatatac accaaaatca
   116281 aaaagtatcg gaaatagtca aatcctagat agagattata caagacgaga agaaatcgag
   116341 atcgttatca aagaaatggc cgaccaagtc ggcactcgct tgagacgatc tgcagcaaaa
   116401 acacaagtag tcagcttatg ggtaggatac tctttaggct atcttgatcc aaatggcaag
   116461 accgggtttc accagcaaat gaaaatcgaa gcgacaaatg ctagcagaga tctagcagat
   116521 gctttattga ccattttcca ccagcattac cactaccagg atattcggcg tgtaggcgtg
   116581 aactgttccg acctcgtata cgcgacaggt ttacagctta acctttttga agatcctgaa
   116641 aagcagataa atgaagcgaa agttgatttt gttgtcgata cgattagaaa aaaatacggc
   116701 tttcaatcaa tcatccatgc gcatagtctc ttgcaaggag gacgcgccat cgcacgtagt
   116761 tctctcgttg gcgggcatgc aggtggtatg agtggattag aaggtggaaa agatgagacg
   116821 gacagcaaaa aaattcattg actataacga gtatcgagat cggccatttg gattaaaatg
   116881 ggggactgct tttgcgatgg aagaactagt caacggtatc aaaaaaaatg aagaagaagc
   116941 acgcaaacag cctcttccta aacaacaaat gacattgcaa gaaatcgata gtatactgac
   117001 agaagccttt ttatctcgta aagcagtaat cattcagctc aatttaaaag atgaatttgg
   117061 aagactcttg gatgaggtcg aagggcactt cattggtgaa gcctatgaag attactttat
   117121 gattgaccat cagccgatat tgtgggaaga cgtacggtat attgagttaa aggaaacaaa
   117181 aaaatggttt gtgacatgag aggttgtgac agaagtgatc aacttcaaaa aataagaaag
   117241 gatttttcga aaattgcttc ttaaattttt gtggaatttt ggcttatttt tcgaagaagc
   117301 aacttctgga acaacgtata ttagatatca gaggttgtga aaaagtcgct tagttttgag
   117361 taacaagcca aggcgctgat ttcacaacct ctgtctatct atccatctat tcggtaagat
   117421 tcatgcatga cgtcttcttt atttagtatg tagagccctt tttcttctga ccattcaaca
   117481 taaatcagct gttttacatc tgcatagcct tctttcttca agttctccat aagccatgct
   117541 tcagtcaatt gattggactg aagcacttta tgctgaattt gcccttcatc tacaagcagg
   117601 atcgataaag ctttgtcttc atctgatttt ttcaatacac tcatttgacc ggcattctct
   117661 aggataacat gtttggcatt ttcaagaaaa aagcattctt gctgtcttaa gattgctcgc
   117721 aactgctcca tctcgatatg gttatttgtc aactctgtca tgttgatgac gccgtctttg
   117781 attagaacag atggctcgcc tttgacccaa cgattgacct tttcattttt ttggacgata
   117841 cgttcgatac cataaatcat tactgcccaa agcgcaatgg caaataggac atgccctaca
   117901 tggacattgt catcataggt tgattcttct aagatcccac ctaaaacaag cgtatagact
   117961 aaatcaaacg gtgtgatttc tgacatggat ttcttcccaa gcaaacgtac cactaataat
   118021 aaaccgatca acccgaacac cagtttcatt gtaattgaaa aaatcatttt ttctccccct
   118081 aactatctgt taattaaatt atatatgctt tctcacgaac acgcatggaa tatacaagga
   118141 agaaatgtat ccttttacta aaaaaaggac tgtgacactg tagtgacccc caaaagttag
   118201 acttttttgg agtggagaaa tccactcctt ttttttatgc tctaaaatga tatttttaca
   118261 caaccgttac ggttgtttta cgaaattgga cg
//
LOCUS       DAFEIE010000003        93469 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFEIE010000003
VERSION     DAFEIE010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 93469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.003"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            85..972
                     /locus_tag="LP345_000249"
     CDS             85..972
                     /locus_tag="LP345_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL1759065.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="LP345_000250"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="LP345_000250"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBL1759066.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="LP345_000251"
     CDS             2274..2720
                     /locus_tag="LP345_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL1759067.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="LP345_000252"
     CDS             2993..4345
                     /locus_tag="LP345_000252"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBL1759068.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="LP345_000253"
     CDS             4516..4803
                     /locus_tag="LP345_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759069.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5029..5472
                     /locus_tag="LP345_000254"
     CDS             5029..5472
                     /locus_tag="LP345_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1759070.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5478..6662)
                     /locus_tag="LP345_000255"
     CDS             complement(5478..6662)
                     /locus_tag="LP345_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1759071.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGCAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6930..7628
                     /locus_tag="LP345_000256"
     CDS             6930..7628
                     /locus_tag="LP345_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL1759072.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7635..8312
                     /gene="nth"
                     /locus_tag="LP345_000257"
     CDS             7635..8312
                     /gene="nth"
                     /locus_tag="LP345_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBL1759073.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8438..8971)
                     /locus_tag="LP345_000258"
     CDS             complement(8438..8971)
                     /locus_tag="LP345_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759074.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9268..11649)
                     /locus_tag="LP345_000259"
     CDS             complement(9268..11649)
                     /locus_tag="LP345_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL1759075.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11639..12286)
                     /gene="recU"
                     /locus_tag="LP345_000260"
     CDS             complement(11639..12286)
                     /gene="recU"
                     /locus_tag="LP345_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBL1759076.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12350..12889
                     /locus_tag="LP345_000261"
     CDS             12350..12889
                     /locus_tag="LP345_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBL1759077.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12979..13398
                     /gene="gpsB"
                     /locus_tag="LP345_000262"
     CDS             12979..13398
                     /gene="gpsB"
                     /locus_tag="LP345_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBL1759078.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13420..13787
                     /gene="rnpB"
                     /locus_tag="LP345_000263"
     ncRNA           13420..13787
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LP345_000263"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13996..15162
                     /locus_tag="LP345_000264"
     CDS             13996..15162
                     /locus_tag="LP345_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBL1759079.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15208..16704
                     /locus_tag="LP345_000265"
     CDS             15208..16704
                     /locus_tag="LP345_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBL1759080.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16785..17468
                     /locus_tag="LP345_000266"
     CDS             16785..17468
                     /locus_tag="LP345_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1759081.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18113..19303
                     /locus_tag="LP345_000267"
     CDS             18113..19303
                     /locus_tag="LP345_000267"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBL1759082.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19405..20358
                     /locus_tag="LP345_000268"
     CDS             19405..20358
                     /locus_tag="LP345_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBL1759083.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20427..21776
                     /locus_tag="LP345_000269"
     CDS             20427..21776
                     /locus_tag="LP345_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1759084.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVRKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVSAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21959..22282)
                     /locus_tag="LP345_000270"
     CDS             complement(21959..22282)
                     /locus_tag="LP345_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759085.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22411..23574
                     /locus_tag="LP345_000271"
     CDS             22411..23574
                     /locus_tag="LP345_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL1759086.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23644..24993
                     /locus_tag="LP345_000272"
     CDS             23644..24993
                     /locus_tag="LP345_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1759087.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25038..25469)
                     /locus_tag="LP345_000273"
     CDS             complement(25038..25469)
                     /locus_tag="LP345_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1759088.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25857..28499
                     /gene="alaS"
                     /locus_tag="LP345_000274"
     CDS             25857..28499
                     /gene="alaS"
                     /locus_tag="LP345_000274"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBL1759089.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28699..29308
                     /locus_tag="LP345_000275"
                     /pseudo
     CDS             28699..29308
                     /locus_tag="LP345_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
     gene            29430..30578
                     /locus_tag="LP345_000276"
     CDS             29430..30578
                     /locus_tag="LP345_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL1759090.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30616..31029)
                     /locus_tag="LP345_000277"
     CDS             complement(30616..31029)
                     /locus_tag="LP345_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBL1759091.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31108..31539
                     /locus_tag="LP345_000278"
     CDS             31108..31539
                     /locus_tag="LP345_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBL1759092.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31638..31871)
                     /locus_tag="LP345_000279"
     CDS             complement(31638..31871)
                     /locus_tag="LP345_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBL1759093.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32054..33724
                     /locus_tag="LP345_000280"
     CDS             32054..33724
                     /locus_tag="LP345_000280"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBL1759094.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33871..34257
                     /locus_tag="LP345_000281"
     CDS             33871..34257
                     /locus_tag="LP345_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759095.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34244..34942
                     /locus_tag="LP345_000282"
     CDS             34244..34942
                     /locus_tag="LP345_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1759096.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34947..35411
                     /locus_tag="LP345_000283"
     CDS             34947..35411
                     /locus_tag="LP345_000283"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBL1759097.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35408..36319
                     /locus_tag="LP345_000284"
     CDS             35408..36319
                     /locus_tag="LP345_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL1759098.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36554..37093
                     /gene="pyrR"
                     /locus_tag="LP345_000285"
     CDS             36554..37093
                     /gene="pyrR"
                     /locus_tag="LP345_000285"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBL1759099.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37107..38390
                     /locus_tag="LP345_000286"
     CDS             37107..38390
                     /locus_tag="LP345_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBL1759100.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38403..39329
                     /locus_tag="LP345_000287"
     CDS             38403..39329
                     /locus_tag="LP345_000287"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBL1759101.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39348..40628
                     /locus_tag="LP345_000288"
     CDS             39348..40628
                     /locus_tag="LP345_000288"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBL1759102.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40633..41709
                     /gene="carA"
                     /locus_tag="LP345_000289"
     CDS             40633..41709
                     /gene="carA"
                     /locus_tag="LP345_000289"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBL1759103.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41714..44899
                     /gene="carB"
                     /locus_tag="LP345_000290"
     CDS             41714..44899
                     /gene="carB"
                     /locus_tag="LP345_000290"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBL1759104.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44953..45729
                     /locus_tag="LP345_000291"
     CDS             44953..45729
                     /locus_tag="LP345_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBL1759105.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45726..46658
                     /locus_tag="LP345_000292"
     CDS             45726..46658
                     /locus_tag="LP345_000292"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBL1759106.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46655..47371
                     /gene="pyrF"
                     /locus_tag="LP345_000293"
     CDS             46655..47371
                     /gene="pyrF"
                     /locus_tag="LP345_000293"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBL1759107.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47378..48007
                     /locus_tag="LP345_000294"
     CDS             47378..48007
                     /locus_tag="LP345_000294"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBL1759108.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47995..48309
                     /locus_tag="LP345_000295"
     CDS             47995..48309
                     /locus_tag="LP345_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759109.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48347..48988
                     /locus_tag="LP345_000296"
     CDS             48347..48988
                     /locus_tag="LP345_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1759110.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49031..49723
                     /locus_tag="LP345_000297"
     CDS             49031..49723
                     /locus_tag="LP345_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBL1759111.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49720..50622
                     /locus_tag="LP345_000298"
     CDS             49720..50622
                     /locus_tag="LP345_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1759112.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50780..52486)
                     /gene="efbA"
                     /locus_tag="LP345_000299"
     CDS             complement(50780..52486)
                     /gene="efbA"
                     /locus_tag="LP345_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBL1759113.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            52676..53299
                     /locus_tag="LP345_000300"
     CDS             52676..53299
                     /locus_tag="LP345_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759114.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53749..54798
                     /locus_tag="LP345_000301"
     CDS             53749..54798
                     /locus_tag="LP345_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1759115.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54795..55676
                     /locus_tag="LP345_000302"
     CDS             54795..55676
                     /locus_tag="LP345_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759116.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55679..56449
                     /locus_tag="LP345_000303"
     CDS             55679..56449
                     /locus_tag="LP345_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1759117.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56728..57582
                     /gene="aroE"
                     /locus_tag="LP345_000304"
     CDS             56728..57582
                     /gene="aroE"
                     /locus_tag="LP345_000304"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBL1759118.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57760..58923
                     /locus_tag="LP345_000305"
     CDS             57760..58923
                     /locus_tag="LP345_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1759119.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59040..59450
                     /locus_tag="LP345_000306"
     CDS             59040..59450
                     /locus_tag="LP345_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1759120.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59624..61852
                     /gene="topB"
                     /locus_tag="LP345_000307"
     CDS             59624..61852
                     /gene="topB"
                     /locus_tag="LP345_000307"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1759121.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGNLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            62023..62307
                     /locus_tag="LP345_000308"
     CDS             62023..62307
                     /locus_tag="LP345_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759122.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            62467..62703
                     /locus_tag="LP345_000309"
     CDS             62467..62703
                     /locus_tag="LP345_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1759123.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62700..63098
                     /locus_tag="LP345_000310"
     CDS             62700..63098
                     /locus_tag="LP345_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBL1759124.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(63765..64709)
                     /locus_tag="LP345_000311"
     CDS             complement(63765..64709)
                     /locus_tag="LP345_000311"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL1759125.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(65005..65949)
                     /locus_tag="LP345_000312"
     CDS             complement(65005..65949)
                     /locus_tag="LP345_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759126.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66170..67384
                     /locus_tag="LP345_000313"
     CDS             66170..67384
                     /locus_tag="LP345_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1759127.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            67406..69421
                     /locus_tag="LP345_000314"
     CDS             67406..69421
                     /locus_tag="LP345_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBL1759128.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(69504..70877)
                     /locus_tag="LP345_000315"
     CDS             complement(69504..70877)
                     /locus_tag="LP345_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL1759129.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(70903..71187)
                     /locus_tag="LP345_000316"
     CDS             complement(70903..71187)
                     /locus_tag="LP345_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1759130.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(71189..73204)
                     /locus_tag="LP345_000317"
     CDS             complement(71189..73204)
                     /locus_tag="LP345_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1759131.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(73383..73688)
                     /locus_tag="LP345_000318"
     CDS             complement(73383..73688)
                     /locus_tag="LP345_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBL1759132.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(73777..74808)
                     /locus_tag="LP345_000319"
     CDS             complement(73777..74808)
                     /locus_tag="LP345_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1759133.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            75015..75890
                     /locus_tag="LP345_000320"
     CDS             75015..75890
                     /locus_tag="LP345_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1759134.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(76042..76884)
                     /locus_tag="LP345_000321"
     CDS             complement(76042..76884)
                     /locus_tag="LP345_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1759135.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(76976..78853)
                     /locus_tag="LP345_000322"
     CDS             complement(76976..78853)
                     /locus_tag="LP345_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1759136.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(78850..80271)
                     /locus_tag="LP345_000323"
     CDS             complement(78850..80271)
                     /locus_tag="LP345_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1759137.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(80274..83663)
                     /locus_tag="LP345_000324"
     CDS             complement(80274..83663)
                     /locus_tag="LP345_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL1759138.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            83920..85312
                     /locus_tag="LP345_000325"
                     /pseudo
     CDS             83920..85312
                     /locus_tag="LP345_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(85385..86032)
                     /locus_tag="LP345_000326"
     CDS             complement(85385..86032)
                     /locus_tag="LP345_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL1759139.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(86040..86726)
                     /locus_tag="LP345_000327"
     CDS             complement(86040..86726)
                     /locus_tag="LP345_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759140.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(86732..87805)
                     /locus_tag="LP345_000328"
     CDS             complement(86732..87805)
                     /locus_tag="LP345_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759141.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            88027..88701
                     /locus_tag="LP345_000329"
     CDS             88027..88701
                     /locus_tag="LP345_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1759142.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            88706..90046
                     /locus_tag="LP345_000330"
     CDS             88706..90046
                     /locus_tag="LP345_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1759143.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(90195..91181)
                     /locus_tag="LP345_000331"
     CDS             complement(90195..91181)
                     /locus_tag="LP345_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBL1759144.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            91905..92936
                     /locus_tag="LP345_000332"
     CDS             91905..92936
                     /locus_tag="LP345_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1759145.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            93045..>93469
                     /locus_tag="LP345_000333"
     CDS             93045..>93469
                     /locus_tag="LP345_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL1759146.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT        29896 a        16580 c        18970 g        28023 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg
     4981 aataggaaac aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga
     5041 caactgctaa tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca
     5101 gaaatggaaa aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc
     5161 gggaaaatcc ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga
     5221 gccatcagta agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc
     5281 gaagagaata aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat
     5341 agacacgagc aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg
     5401 tcaaaagaag aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga
     5461 agtagcaaat gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa
     5521 aatccgaata ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg
     5581 ccgatgacgc gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg
     5641 ttatctgaga cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg
     5701 aaaccataac agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat
     5761 gtgatgaata gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct
     5821 gaaaattttt tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca
     5881 atcaaagaga agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat
     5941 tgagaaaaga tagattgaag agagccagct gccaaccaaa cagcacaacc tgctgtcaat
     6001 aaaggaataa cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg
     6061 gagaaactta aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag
     6121 ccataaacgg catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc
     6181 aactcagcta atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca
     6241 cccatccatc caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca
     6301 tataaggtgg agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc
     6361 catatcgaat ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata
     6421 ataaggatcg gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag
     6481 aaggcagcta gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg
     6541 gagtgagaat aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat
     6601 ccagtgaata agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac
     6661 atgtaaaaac tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt
     6721 ttgtttcctt gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa
     6781 agtgaagata cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc
     6841 tgaccgatca gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac
     6901 gtatactgtg attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg
     6961 gacaaacagt catatctaat cttttactta aaaattatca taggatcggt ctacaatctg
     7021 aagaattttt atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg
     7081 atttgcagat gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg
     7141 atcgtctcgt aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag
     7201 cagatcgata taatctttac cccatctatg atctattagg tgagtattta aaaacacaag
     7261 aaaaaaaata cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg
     7321 aacaagaatt tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag
     7381 aagaagacca ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc
     7441 aggcttatag ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac
     7501 gtacaaaaca acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag
     7561 aagtagaaca gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg
     7621 aggagtagcg gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg
     7681 gaatgtttcc cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg
     7741 cagtgatctt aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt
     7801 ttgcctcttt tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta
     7861 aaataaaaac gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc
     7921 agctgattga acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc
     7981 ctggtgtagg cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa
     8041 tcgcagtaga tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg
     8101 ctacggtcat ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa
     8161 agacacatca tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt
     8221 gcgaggtatg tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag
     8281 aaaaggcgct aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg
     8341 tatgaattat cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa
     8401 gtaaatgtac atactcagta gctaggatgg taacttatta caatttattg cgataaaaat
     8461 aaaagttgtt atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac
     8521 ctataaaata agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag
     8581 gtgtaataaa aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa
     8641 tggatttggg cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata
     8701 aaaaagtgag aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc
     8761 ttaaaagtac agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta
     8821 ataataaaca aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata
     8881 aaaaaagatg gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga
     8941 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
     9001 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
     9061 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
     9121 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
     9181 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
     9241 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
     9301 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
     9361 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
     9421 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
     9481 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
     9541 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
     9601 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
     9661 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
     9721 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
     9781 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
     9841 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
     9901 taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc
     9961 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
    10021 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
    10081 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
    10141 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
    10201 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
    10261 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
    10321 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
    10381 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
    10441 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
    10501 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
    10561 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
    10621 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
    10681 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
    10741 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
    10801 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
    10861 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
    10921 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
    10981 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
    11041 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
    11101 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
    11161 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
    11221 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
    11281 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
    11341 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
    11401 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
    11461 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
    11521 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
    11581 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
    11641 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
    11701 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
    11761 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
    11821 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
    11881 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
    11941 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
    12001 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
    12061 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
    12121 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
    12181 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
    12241 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
    12301 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
    12361 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
    12421 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
    12481 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
    12541 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
    12601 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
    12661 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
    12721 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
    12781 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
    12841 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
    12901 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
    12961 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
    13021 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
    13081 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
    13141 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
    13201 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
    13261 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
    13321 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
    13381 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
    13441 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
    13501 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
    13561 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
    13621 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
    13681 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
    13741 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
    13801 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
    13861 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
    13921 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
    13981 ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
    14041 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
    14101 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
    14161 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
    14221 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
    14281 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
    14341 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
    14401 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
    14461 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
    14521 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
    14581 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
    14641 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
    14701 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
    14761 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
    14821 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
    14881 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
    14941 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
    15001 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
    15061 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
    15121 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
    15181 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
    15241 gaaatcaatc ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg
    15301 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
    15361 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
    15421 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
    15481 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
    15541 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
    15601 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
    15661 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
    15721 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
    15781 cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg
    15841 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
    15901 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
    15961 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
    16021 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
    16081 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
    16141 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
    16201 ttttatcgtt cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
    16261 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
    16321 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
    16381 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
    16441 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
    16501 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
    16561 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
    16621 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
    16681 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
    16741 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
    16801 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
    16861 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
    16921 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
    16981 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
    17041 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
    17101 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
    17161 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
    17221 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
    17281 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
    17341 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
    17401 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
    17461 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
    17521 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
    17581 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
    17641 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
    17701 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
    17761 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
    17821 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
    17881 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
    17941 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
    18001 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
    18061 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
    18121 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
    18181 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
    18241 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
    18301 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
    18361 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
    18421 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
    18481 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
    18541 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
    18601 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
    18661 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
    18721 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
    18781 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
    18841 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
    18901 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    18961 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    19021 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    19081 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    19141 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    19201 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    19261 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    19321 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    19381 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    19441 attggttcag agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg
    19501 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    19561 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    19621 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    19681 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    19741 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    19801 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    19861 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    19921 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    19981 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    20041 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    20101 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    20161 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    20221 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    20281 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    20341 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    20401 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    20461 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    20521 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    20581 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    20641 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    20701 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    20761 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    20821 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    20881 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtccgca
    20941 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    21001 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    21061 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    21121 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    21181 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    21241 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    21301 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    21361 ctggaatgcg tctcccttat gttatggcaa aagaaaacaa cctgcctttt agcaagctct
    21421 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    21481 gcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    21541 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    21601 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    21661 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    21721 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    21781 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    21841 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    21901 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    21961 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    22021 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    22081 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    22141 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    22201 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    22261 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    22321 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    22381 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    22441 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    22501 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    22561 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    22621 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    22681 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    22741 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    22801 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    22861 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    22921 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    22981 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    23041 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    23101 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    23161 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    23221 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    23281 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    23341 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    23401 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    23461 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    23521 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    23581 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    23641 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    23701 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    23761 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    23821 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    23881 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    23941 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    24001 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    24061 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    24121 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    24181 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    24241 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    24301 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    24361 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    24421 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    24481 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    24541 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    24601 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    24661 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    24721 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    24781 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    24841 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    24901 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    24961 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    25021 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    25081 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    25141 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    25201 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    25261 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    25321 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    25381 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    25441 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25501 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25561 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaaat aagtacgaaa
    25621 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25681 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25741 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25801 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25861 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac
    25921 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25981 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    26041 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    26101 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    26161 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26221 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26281 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26341 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26401 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26461 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26521 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26581 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26641 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26701 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26761 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26821 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26881 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26941 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    27001 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    27061 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    27121 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27181 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27241 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27301 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27361 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    27421 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27481 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27541 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27601 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27661 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27721 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27781 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27841 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27901 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27961 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    28021 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    28081 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    28141 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28201 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28261 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28321 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28381 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28441 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28501 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28561 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28621 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28681 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28741 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctgggttc cttggctggg
    28801 gtttattcca ttaggattca ttagtttaac aattatccat atcacagtaa ttattgctgc
    28861 agtagtatta ggcccaaaag atggcatggt gattggcttg ttttggggaa tcgctacaat
    28921 tgttcgtgcc tatgccatgc caacaacgcc atttgataca ttagtgttca cgaatccgat
    28981 tatctcggta gttcccagag tacttgttgg cttagtagca ggcttggttt tccactggat
    29041 ttatcaaaaa aataaatcaa taacgatcag ctcagccttt gcaggggtac tgggttcatt
    29101 ggtcaataca gtcttagtgt taggattcat gggattattt tatacaggtg caacggcaga
    29161 tgcctatggt gtagactctg ctcttttatt taaaacctta gcaggggttg cagcaatcaa
    29221 tgggatacca gaagcaatag gtgcgggaat cataacacca ttactagcaa aagcgttatt
    29281 tgcagcaaca ccgttgaaac cagaataatg accatctttt aatagtaata ggacgcacga
    29341 tagatagaaa aaggaagaga ggagaggaaa acaatcgtcc tctccatctt tttacctgag
    29401 caacaagcaa actagaaggg gtaaaaaact tggctaagaa acaagaagaa aaaaagaaac
    29461 aaataccgca acagcggaca aaaaaaggag tactagcggg tatcttagga ttggttacga
    29521 atctgatctt gtttgtctct aagctaatga tcgggctttt ttcaggaagt gtctccatta
    29581 tggctgatgc agtgaacagt ctatcagata ctgcttcatc catattgact ttgatcggat
    29641 ttaaaattgc tgcaaagcca gcagatcagg aacatcctta tggacacgaa cgcttcgaat
    29701 atatcagtgg gttatttgtt tcgatcatca ttacttatgt aggatttcaa tttttagagt
    29761 cttctgctga aaaaatcatc catccagaaa atgtctcttt aacacccatc gtcttttttg
    29821 tcctaatcat ttccatcttt ttgaaatttg cacaaggcaa aatgtatcag gttattgcgc
    29881 aatccattga ttctgaaaca ttgagagcta cagcaacaga tagttataat gatgtcttta
    29941 ctacactggc tgtattgctt tcagcagcaa tcgaatgggt aactggatgg cgtattgatg
    30001 gatatatagg ttttgcttta gcattatata tcctttatag tggattgacg atgcttcgaa
    30061 attttgtata cgaactatta ggaagtcgcc caacgccagc agagattgaa gaaatggaag
    30121 agcatttaaa tgcttgcgat gatatacttg gctatcatga tttattggtg cataactatg
    30181 gacccaataa acgctttgca tcagtccaca tcgaagtaga tgaatcaatg aatttgaatg
    30241 tggctcataa gattattgat ctgatagaaa aagactttaa aaagtctttg gatgtggaac
    30301 ttgtctgtca cttggatcca atgcctgttg ataacgaaaa atactataat atcttgcggc
    30361 agttaaagca aattcttctt gaaacaggta cagggcttaa tattcatgat tttagagtaa
    30421 ttcatcaagg aaaaacgctg caatttgatg tagtggtccc tgagaaattc cagtttgttg
    30481 atacagaact agaaagaatc ttacgtagtc aaatagaaga aaaaatcgga gattaccaat
    30541 tggaaattac gtttgatcac aattatcttt tatattaaat gagaaactat aaaaagactc
    30601 cttaaagttt ttaatttaaa gagtcttttt ttcttttaat tgtttatgga gagcctgacg
    30661 tgcaagatta tctgctcctt tatttttgtt ttcgggcaac cattgcagga tcaataaaga
    30721 aaattcggat agaagttctt ggattctttg aaggtaggga aggaagagct cgttcttcgt
    30781 tgcgtttttg tcgaccgtag aaactagtgt tttgctgtct gaaaaacaga aaatcgtttc
    30841 attctgtaag tcgtttttct ttagaaattc taaagttttt aaaaagactt cgaactctgc
    30901 ttgatggttt gtccctatag aaagcgggat agatagctgt tcttgtttac cttgatagac
    30961 aatcaagatt ccacctccac taggaccagg gttgcctttt gtagaggcat caatgtatac
    31021 ttttaacata aaaagagatt ctcctttttg ttcaaactaa tgttatggta agattatatc
    31081 attactgaat cggtgagagg ttagagaatg aaaaaaaata ttcgatggca gcctgaactg
    31141 gcacatacga tcatctattg gtcattgacc ttgatcattc tgttttttag tctgattctt
    31201 tctttagaaa acacaggtcc ttattggaaa agcaattttg ttttaggtat ttttcttgtt
    31261 tttctatttc taggtttgcg gcgttctttt attttaaaat caaactctgt gattatacgt
    31321 tatgctgctt tttggaaaga ccgagaaata tctgtcggac agattcgatc tttgacgcca
    31381 actaatactg gggtgcaaat gatgttgcaa gatgagaaag ccccatctgt tttcatgatg
    31441 cgaaaaaaag atcaagtagt cctttttgat cattttgaaa aaaacggacc caaatcagaa
    31501 tcaattcctt atccttatac gaaaaaaaga aaaagctaat tttaaaaatc agaacctaaa
    31561 aaaacgaatt tttacaggaa aagaaaagag tgagacgtac ggttcatccc gtttagcgtc
    31621 tcactctatt tgtttatcta ttcatgcata ctagtatcgg tagtctgaac gttgcctttc
    31681 ttgacatggg cagcttgtgt tcctcgattc ccttcgatga tctcaaattc gaccacttga
    31741 ttttcttcca aagttttgaa tccctcttct tcaatcgcag taaaatgtac aaaaatttct
    31801 tctgtgtcat cataactgat aaagccgtat ccttttttgt tgtcaaacca ttttacaatt
    31861 cctgtggtca aagcactcac gacctttcta aagtctgatc atagccttca ttataaagag
    31921 tatttataag tacgtcaaat aaattaaaaa cctgtaattt tatgtttttt ttctgaataa
    31981 aaaaaggtat aattggcata tcttaacaaa gaagatattt tgttgaataa agttcgtgaa
    32041 aaggggtaat caaatgaaga atgatctgca aatttcacaa gaaacagagc tagaaccgat
    32101 tgttgaagtg gctagtaaat tagatcttaa ggaagacgat ttggaactgt atgggaaata
    32161 taaggcgaaa atcaattttt ctggaatcaa tcgatcaaag gataacgctg aggggcattt
    32221 gatcttagtt acttccatca atccaacacc agctggcgaa ggaaagtcaa cgatcactgt
    32281 agggttagga gacgcgctca ataaaatcaa taaaaaatct gttattgcat tgcgagaacc
    32341 ctcacttggt cctgtgatgg gaatcaaagg tggtgctgca ggcggaggat atgcacaggt
    32401 attgcctatg gaagatatca acttgcattt tactggtgac atgcatgcta tcacaacagc
    32461 taataatgca ttatctgctc ttttagataa tcatattcat caaggaaatg aattgaacat
    32521 cgatgcccgc cgagtgattt ggaaacgggt agtcgatctc aatgatcgtg aactgcgtaa
    32581 agtaattgtt ggcttgggtg ggccaatcca aggtgttcca agagaagatg ggtttgatat
    32641 cacagttgcc agcgaaatca tggctatctt gtgtcttgcg gcagaccttg aagatttaaa
    32701 ggctcgtctt gcaaggatcg ttgtcggcta tacatttgac cgtcagcctg tgactgctgg
    32761 agacttgaaa gcagaaggcg ctctggcatt actgctgaaa gatgcaatca agccgaatct
    32821 tgtacaaaca atttacggaa caccagcttt tgtccacggg ggaccgtttg ccaatatcgc
    32881 tcatggctgc aatagtattt tagctaccaa gacagcattg agattagcag attacgttgt
    32941 cacagaggca ggatttggtg cagatcttgg cggagagaaa tttttagata tcaaagtacc
    33001 taacttgaaa aaagcgccgg atgctgtggt gattgtcgcc actgtccgtg cattgaaaat
    33061 gcatggcgga atgaaaaaag atgaacttaa aaatgagaat cttgatgctt tgaaagtagg
    33121 ttttgcaaat ttaaagcgcc atatacgtaa tatggaacaa tatcagctac ctgtgatcgt
    33181 cgcaatcaat gaattcgtaa cagatacaga caatgaactc acactgttgg agcacttgtg
    33241 tgaaaatcag gggattcttg ccaagagagc gagtgtatgg gcagatggag cagaaggcgg
    33301 cgttgattta gcaaaagctg tagtacgatt gattgataga aaagaagcta attacaagcc
    33361 attataccgc ctagaagaaa cgatacaaga aaagacagaa acaatcgtca agaaaattta
    33421 cggaggaaat ggtgttgttt tcagcaaaaa agcgcaaaaa caaatagaag agtttacgaa
    33481 gaatggatgg gacaaactgc cgatttgtat ggcaaaaaca cagtattcat tttctgatga
    33541 tccttcactg ctaggtgcac cggaagattt caccatcacg atccgcgaaa tcatcccaaa
    33601 attaggggca ggatttttag tagccttgac tggagatgtt atgacgatgc ctggtttgcc
    33661 taaaaaacct gctgcattga atatggacgt gacaaatgac ggagaagtgt tgggattgtt
    33721 ttaagcttga ttataatcta ccatcgaagg agctgtattt tgactacagc ttcttttttt
    33781 agacgatagg gaattaattt tgtttacact aggatcattc tttttcttta ttgtattttg
    33841 agctatacta aagcataata ggagggtatg atgaaaacga catttataag aaaaaccggt
    33901 ttttacggta tgggtagctc gattcagcta agaatcaaca atgaaaaacg cagtgttctc
    33961 agtcatgaac aaaagataac gcttgatctg gaagtgccct ttacgatgca ggtcaccttt
    34021 tattggctaa aaagccccgt ttatacagtg aaagaagcaa agcctgctta tgtgatcaca
    34081 atgaattact tgattcttca aatctatccg tttttatttc tagcaactgg gttgggggcc
    34141 gttttcctac aaaatttatt tttcagtttt tttgcagtta ttgtgttgat tgcgttcttt
    34201 ttctatataa aaaaccgggc atatttgatc aaggaggaaa attatggcaa actctgatct
    34261 ttttttaatc agtttcaatc gaatcgaaaa atggatgaga gacgagatgg gaaatgcacg
    34321 aaatatggga tttaccgaac ttgtcagacg cctagctcaa agaaaacaat taatgatcag
    34381 aaaatacgaa gatgatcttt tacagcttgc tcagttaagg aatgcgatcg tccatgatcg
    34441 gatcgcagtc gattttgtca ttgcagagcc aaatgattgg acagtcaagc gaatccagct
    34501 gatcgaacaa gaactgattc agcctgaaac cgtgctgcct cgatttgcaa aacgtgtaac
    34561 aggttttgaa caagatcttc cgttacttga actgttaaag atagtagcag aaaaaaggta
    34621 ttcacaattt ccgttataca ataaaggaaa atttgtagca ttgattactt tacgtaatat
    34681 cgggttttgg ctagcaaaag aaagccaaaa aggtccggtt gatttaacaa ataaacgagc
    34741 gttggatttg atcatccaaa acggaaagta cacaaattat cattttgttc cagctaaaac
    34801 acatatttac gaggttgaag cgatgtttcg tgagcaaggg actttggaag ccgtacttat
    34861 cactaaagat gggaatcccg atggtaatct gctcgggatc gtacgacctc gtgatattta
    34921 taaacaaata gaaaaggatt gattttttgt taattattta ttggatattc agcgctttgc
    34981 tagtaggagt ggatcagttg gtcaaatggt ggatcactga taatctagcg cttggagaga
    35041 cgaaaaatct tataccaggt attttgtcac tgaatcatat tcgaaacact ggagccgcat
    35101 ggagtatgct agaagggaag atgtggttct ttactatagt gacactcatt gcagtcgttg
    35161 tgattctcac attgatgatt aaaaatcgtg aaaaaggtaa tcgctggttc atgattggat
    35221 tgagtttgat tctagctggt gcgattggca attttatcga ccgtattcgt cttggctatg
    35281 tagtagatat gttccagaca gattttatga gctttccgat ttttaacgta gcagatgtga
    35341 cacttgtatg tggagtgatt tgtatgttaa tttatattat tttagatgaa aaggatcaaa
    35401 gaaaaaaatg acagaactta aaacgacgat tcaccatgaa tctggtagga tcgataaagt
    35461 attgactaat ttattcaccg attacagtcg ttcgcaaatt cagctgtggc tgaaaaatgg
    35521 agcggtttct gtcaatggac agccagtcaa agcaaattac aaagtaaaac aaggagacga
    35581 gattactgtc ttgatccccg aaccagaaac attagatgtg gtcccagaaa atatcccgtt
    35641 gacgatcgtt tacgaagatg aagatgtagc ggtgataaac aaacctcaag gaatggtcgt
    35701 tcatccttca gcaggtcata cgcatggcac aatggtcaat gcgctgatgt accatatcaa
    35761 ggatctttct acgatcaacg gcgttattcg tccaggtatt gttcaccgaa tcgacaaaga
    35821 tacttccgga ctgctaatgg ttgccaaaaa tgaccaggca cacgaatcat tagctcagca
    35881 attaaaagat aagacctctt tgcgcaaata tgttgcttta gtccatggag agattcctca
    35941 cgaaaaagga accatcaatg cgccaatcgg ccgttcgaag gaaaaccgga aaatgcaggc
    36001 gataagagaa gatgggaagt cggctgtcac acattttact gtattggaac gtttcgaagg
    36061 atttactctg gttgaattaa aactagaaac cggaagaaca caccagatcc gtgtgcatat
    36121 gaagtatatc ggttatccgt tagctggaga tccagtatac ggaccgaaga aaactttgaa
    36181 aggcaatggt cagtttctcc atgcgcaaat gttaggtttt acgcacccga ctacaaacga
    36241 aaagatgatc tttgaagcac ctcttccaga agtttttgaa aaaactttag aaaaattaag
    36301 aaaaaacatt gcattttaat ttagataacg gtatagtaat taacaacgaa agcataaaac
    36361 ttaatagaat tcctttaagt ttagtcccgt gaggctaaga agggtgggag caaggatacg
    36421 tatggtgcgc cataagtaga ttgctcattg acatagtata gctatcagtg tatcagtata
    36481 cgctcagtct aaacattcct cctgtcctct tagggcagga gtttttttat gcaaaaaagt
    36541 agggggaatg aaaatgcaag caaaagaagt agtagatcag gtaaccatga agcgagcatt
    36601 gactcgaatt acttatgaga ttatcgagag aaaccatagt atccaagata tcgtattggt
    36661 aggtatcaaa acacgaggaa tctacattgc atcaagaatt gccgaacgcc tgaagcagct
    36721 agaagatatc gatattcctg taggagaact ggatatcact ttataccgag atgacaaaaa
    36781 agaaaatcca gaagaaccgg aacttcattc ttctgacatc ccagtttcct tagaaggaaa
    36841 agaagttatt ttgattgatg atgttttgta tacaggacga acgattcgag cagcaatgga
    36901 cgcagtaatg gattttggca gaccaagaaa aatttcatta gcagtcctgg tcgatcgtgg
    36961 gcatcgagaa ttgccaatcc gtgcagatta tgttgggaag aacattccaa catctcgggc
    37021 ggaagagatt ttagtagaga tgcaagagct tgatggacaa gatcgcatca tgattttgaa
    37081 agaggaagat tagaggagag agaaacatgt cggagaaaaa aggatttcat aatgatgacg
    37141 tggtgttaga tatccacgat cgcccaaccc caggacattg ggtaggatta agtttacaac
    37201 acttgttcac gatgttcgga gcaaccgtgt tagtccccat cttagtaggt atcgatccag
    37261 gtattgcgct agtcagttca ggactaggta cattggtgta cttatttact actaaaggaa
    37321 agatacctgc gtacttagga agcagcttcg ctttcattgc agcgatgcag cttttgatga
    37381 aaacagatgg ttatccagcg attgcacaag gagcagtcac aactggatta gtctatttga
    37441 ttgttgcgct gatcatcaaa aagatcggtt cagcatggct ggataaaatc ttgcctccaa
    37501 tcgtcgtcgg tccagtcatc atggttatcg ggttgggact tgcggcaaat gcagcaacaa
    37561 atgctatgta taatcagggc acgtatgatt tcaagtatat tgctgtagcg ctgatcacat
    37621 taggattaac aattttcttc aacatgtggc taagaggttt tctcggattg attccgattt
    37681 tactaggtat tattagcgga tacatcgtag ccttgctgtt tggaatcgtg gatactaagc
    37741 caatcgtaga cgctgcctgg tttgctgttc ctaactttga gattcccttt gtacaatatg
    37801 aaccaaagct atatcttgga gcaatcacaa caatggcacc catcgctttt gtgacgatga
    37861 cagagcatat cggccatctt atggtattga ataaactaac taaacgtaat ttctttgaag
    37921 aaccgggtct tcataagacg ttgacaggtg atggattagc acaaatcgtg gcagcctttg
    37981 tcggaggtcc tcctgtaaca agttacggtg aaaacattgg tgttctggct atcacacgtg
    38041 tccatagcgt gtttgtgatc ggtggagctg cagtatttgc agtcatttta ggattcgtag
    38101 gaaaattaag cgctttgatt ttaagtatcc ctggaccagt catctcagga atcagtttta
    38161 tcttatttgg agtaattgcc gcaagtggaa tgaagatttt aatcgagaac aaaatcgatt
    38221 ttgataaaaa gaaaaatctg ttgattgctt cagttatctt agtagtagga attggcggac
    38281 tcgtctttga agtaggcaca tttacattgt cggcaatggc attagcaact gtacttggca
    38341 tcattttaaa tcttatctta ccagaaactt cacgaagcga agaaaactaa ggaggaaaca
    38401 ttatgatcat caaatcagaa cgtatcagct taaagcattt attgaccgtt gaggcactta
    38461 ctgatcaaga agttatgggc ttgatccgca gagggcagga attcaagcaa ggtgctaatt
    38521 ggactccgca aaagcgccag tactttgcta caaacctctt tttcgaaaat agtactcgca
    38581 cacataaaag cttcgatgta gcggagaaaa aactagggct agaagtgatt gaatttgaag
    38641 caagcacaag ctctgtccaa aaaggggaaa cactatacga tacagtactg acgatgtcag
    38701 cattaggcgt agacgtagcg gttatccgtc atggtgatga gaactattat gacgaactga
    38761 tacaaagtaa aacaatccag tgttcgatta tcaatggagg agacggaagc ggacagcatc
    38821 caacccaatg cttgcttgat ttgatgacca tttatgaaga atttggtcat tttgaaggtc
    38881 tgaaagttgc catcgtaggt gatatcactc actctcgcgt agctaaatcc aatatgcaga
    38941 tgttaaaacg tctaggcgca caagtattct tctcaggtcc tagagaatgg tacgacgatg
    39001 aattcgaagt gtacggacat tatatgccat tggatgaact actagatcaa gttgatgtca
    39061 tgatgatgct tcgggtgcaa cacgaacgcc atgatggaaa agaaagtttc tcaaaagaag
    39121 gctaccatca ggaacatggg ttaacagttg agcgtgcgaa gaagttgcaa aaacatgcaa
    39181 tcattatgca cccagcacca gttaaccgtg atgtagaatt agctgattca ttagtggaag
    39241 gattacagtc gcggatcgtt cagcaaatga gcaatggagt attcgtcaga atggcaatct
    39301 tagaagcagt gctaaatgga aaagcgtaat tataggagga tgaaaaaatg aaaacactca
    39361 ttaaaaacgg tcagatcaat acacgaaaaa atatgacgac accagcagaa atttggatag
    39421 aagatgggcg aatcaaagca atcggtacag gattctcaga agccgaattt gatgaagtgt
    39481 ttgatgcaaa gggacaattg atcacacctg gtttagtgga cgtccatgtt catttgagag
    39541 agccaggatt tacatacaag gagacgatcg aagctgggac tcgctcagct gctcgtggcg
    39601 gtttcactac tgtatgcgcg atgccgaatt taaatcctgt acctgatacg gcagaaaagc
    39661 tgagacaagt atatgacatc attagaaaag atgcagttgt gaaggtattg cagtatgcgc
    39721 caatcacaga aaatctgcga agtgagaaat tagttgatca agaagcactg attgaagaag
    39781 gtgcttttgc tttcacaaat gacggtgtag gtgtccaaac agctgggacg atgtatctgg
    39841 ctatgaaaga agctgcaaaa aacaataaag ccctagtagc ccatacagaa gatgaatctt
    39901 tattatttgg cggcgttatg cacgctggca agaaggcaga agaacttggt cttcccggga
    39961 tcttaagcgt aaccgagtct tctcaaattg ctagagatct gttgctagct gaagcaactg
    40021 gtgttcatta ccatgtttgc catgtttcta ctaaagaaag tgtccgtgta atcagagacg
    40081 caaaaaaagc aggaatccac gtaacagcag aagtttcacc ccatcatctt attttgatcg
    40141 acgaagatat tcccgaagat ttcggctttt ggaaaatgaa cccgccgcta agaggacggg
    40201 aggacagaga agctttgatc gaaggcttgc ttgacggtac gatcgattgc atcgctacag
    40261 accatgcccc ccatggatta gaagaaaaaa gccaaagttt catgaaatca ccatttggta
    40321 tcgtaggaag cgaaacagcg tttcaactga tctatactca ttttgtagaa actggtcgat
    40381 tcacgttgga acaagtgatc aattggttgg cagttaaacc ggctgagatt tttggtttga
    40441 atgcaggaac gctaacggtt ggtgcccccg ctgatgtagc agtttttgat attacacaaa
    40501 cttgcacgat cgataaagaa gactttttat caaaagggga gaatacacct tttatcggct
    40561 ggaaagtaaa aggcgaaaca caaatgactt ttgtcaacgg aaaacttgtg tggcagaagg
    40621 gagaataaaa gtatggaacg tttgcttata ttagaagatg gaacagtttt cgaaggaaag
    40681 gcttttggtg cagatgctag tgtcttcgga gaaatcgttt ttacaacaag tatgactggt
    40741 tatcaagaaa ctatcactga tcaaagtttt aacggtcaaa tcattacatt tacctatcct
    40801 atggtgggta attatggggt aaatagagat gattatgaat cgatttctcc aacatgcaaa
    40861 ggagtagtag taaaagaaca tgcacgtgta gcttcaaact ggcgaaacca aatgacgcta
    40921 gattcatttt tgaaacaaaa aggaattcct ggaatatcag gtatcgatac gcgcgccctt
    40981 actcgcaaaa tccgtgaagt cggaacgatg aaagctagta tagttgatgc tggagattcc
    41041 ttcgaacatg catttgatca gctgaaagca accgttctag caaccaatca agtgcagcaa
    41101 gtctcaacta acaaacctta tccaagtcca ggaacaggtc ggaaagtcat tgtcattgac
    41161 ttcggcttga aacatagtat tttacgagaa ttgagtaaaa gaaactgtaa cctcacagta
    41221 cttccctata acacagatgc cgagacgatt ttagcgctat caccagacgg agtcatgctg
    41281 acgaatggac ctggtgatcc aaaagatgtg ccagaagcaa tcgaaatgat caaaaaaatc
    41341 caaggaaaag taccgatttt tggtatttgt ctcggtcacc agttatttgc tttagccaac
    41401 ggtgcagata cctataaaat gaaattcgga catcgaggat taaatcaccc ggtacgagaa
    41461 gtagcgaccg gaagaattga ttttacttct caaaatcatg gctatgcagt cgatgaagcc
    41521 acgattgatc cagaaaaact catcgtaact catgtagaag taaatgacgg aacagtagaa
    41581 ggagtcaaac acagagatta tcccgctttc agtgtgcagt ttcatccaga tgctgcccct
    41641 ggtccgcatg atgcactaca tttatttgat gaatttatgg aaatgatgga cgcaggaaag
    41701 gagcagtaaa cagatgccga aacgtacaga tatcaagaaa attatggtga ttggatctgg
    41761 tccgatcatc attggtcaag ccgcagaatt tgactacgca ggaacacaag cctgccttgc
    41821 cttaaaagaa gaaggatatg aagtggtttt agtaaattct aatcctgcga cgatcatgac
    41881 ggataaagaa gtggcagatc aagtatatat cgaaccgatc acacttgaat ttgtatcaag
    41941 gattcttcga aaagagcgtc cagatgctct ccttccaact ttaggcggac agacaggcct
    42001 caatatggca atggagctgg cagcatcagg tattttagaa gaattgaaca tagaacttct
    42061 aggaacaaag ctttctgcga tcgatcaagc agaagatcgt gatctattca aacagttgat
    42121 gaaagaattg aatcagccaa tccccgagtc tgaaatcgtc aatacagtag aagaagctgt
    42181 agattttgca aataaaatcg gctatcctgt catcgttcgt ccagccttta ctttaggcgg
    42241 aactggtgga ggtatgtgtg aaaatgaaga agaattacgt atcgtatcag aaaatggatt
    42301 aagtctttcc cccgctaccc aatgtttgat tgaacgaagt attgcaggtt ttaaagaaat
    42361 tgaatatgaa gtgatgagag attcggctga taatgcaatc gttgtctgca atatggaaaa
    42421 ttttgacccg gtgggtatcc atacaggtga ttctatcgta tttgccccta gtcaaacatt
    42481 gtctgaccat gaatatcaaa tgcttcgtga tgcttctctt tcgattattc gagcacttaa
    42541 gatcgaggga ggctgtaatg tccaactcgc tcttgatcca catagtttta attattatgt
    42601 gattgaagtc aatccgcgtg tttctcgttc atctgcgtta gcaagtaagg cgactggcta
    42661 tccgatcgct aagctagctg ctaaaatagc gcttggatta acattagacg aaatgaaaaa
    42721 tcctgttaca ggaacgactt ttgcagaatt tgaacctgca ttagattatg ttgtagctaa
    42781 aattcctcgc tggccgtttg ataagtttga aaacggagaa cggcttttag gcacgcagat
    42841 gaaagcaact ggtgaagtga tggctatcgg tcggaatatc gaagagtctt tattgaaagc
    42901 tgtgcgttct ttagaaatcg gtacacacca tatcgaactt cctgagttgg cagacatcac
    42961 ggacgatgac ctaatccaaa aagtggttcg agcacaagat gatcgcctgt tttatgtagc
    43021 tgaagctatt agaagagggt acaccataga agaattagcg gatttgacaa aaatcgattt
    43081 attcttttta gataaactgt tgcatatcgt agaaatcgaa cagcagttga aacagcagcc
    43141 gttggatgac aagatattga aaacagcgaa acaaaacggt tttacagaca aaaaagtggc
    43201 ggagctgtgg gaaataaacg aagaagccgt tcgccagatg agaaaagaaa atgatttgat
    43261 tcctgtatat aagatggttg acacttgtgc agcggaattc gaatcaaaaa caccttattt
    43321 ttatagttcc tatgaatatg aaaatgaaag ttcacgatca gaaaagccct caattctagt
    43381 actgggatct ggtcctatcc gtatcggaca aggggttgaa tttgactatg cgactgtgca
    43441 ttctgtcaaa gcaatccagc aggcaggata cgaagcaatc atcatgaaca gcaatcctga
    43501 aacagtttcg actgactttt ctatttcgga taaattatat tttgagccat tgaccttcga
    43561 agatgtgatg aatgtgatcg agctagaaca gccgatagga gtaatcgttc aatttggtgg
    43621 tcagacagca atcaacttag ccgaaccttt gactgctgct ggtgtaaaaa tcttagggac
    43681 aacgatcgaa gacttggatc gtgcggaaaa tcgtgattta ttcgagcaag cgctgaaaga
    43741 gttggatatt cctcaacctt taggggatac tgctacaagt aaagaagaag ccgtggttat
    43801 cgcttcgaga attggttatc cagttcttgt tcgtccaagc tatgtattag gcggacgtgc
    43861 gatggaaatc gttgaaaacc agcgagattt agaagattac atggaacatg ctgtgaaagc
    43921 atctccagaa catccagtac tagtggaccg ttacttgctt ggtggtgaat gcgaagtgga
    43981 tgcgatttgt gacggtgaaa cagtactcat cccagggatc atggagcata ttgagcgtgc
    44041 tggtgtccat tcaggggatt caatggctgt gtatccacct caaacattat ctgaatcgat
    44101 caagaaaacg atcgaagatt acacgatccg cttagcatta ggtttgaatt gtgtcgggat
    44161 gatgaatatc cagtttgtca tccatgaaaa tgaggtttat gtgatcgaag tcaatcctcg
    44221 agcaagtcgg actgttccat tcttaagtaa ggtgacagga attccaatgg cacaaattgc
    44281 gacgaaagct attttgggag agaaactaaa gacacttggt tatgaaaacg gactttatcc
    44341 agaaacaaaa gaagttcatg ttaaagcacc tgtcttttct tttacgaaat tgcagaaagt
    44401 tgatacttac ttagggcctg aaatgaaatc gactggagaa gtaatgggat ctgacagaca
    44461 attagacaaa gctttgtaca aggcattcga agcttctgga ttacacttgc ctgaatatgg
    44521 agccgtatta tttacgattg cggacgaaac aaaagaagaa gcactagaat tagctaaacg
    44581 ttttacagaa attggctata gtctgatagg aacgaaacat acagctgctt atttcgaaaa
    44641 aaatggtctg gtcgttgaaa cagtagcgaa aatttctgag gaagcagcag aaaaaaatgt
    44701 agtcgactta ataagagatg gtaaaacaca agtggttgtc aatacgattg ataaagatcg
    44761 gggaaatgct tctaaagacg gtttcatcat ccgaagagaa gcagttgaac atggtattcc
    44821 attgtttact tctttagaca cagcagatgc gatcgttcga gtgatggaat cccgtgcttt
    44881 ttcaactaac cctatttaac ggcgagcaca tgttaagaca aaaagacgaa aaaccgttgc
    44941 aggaggggac agatgaaaca agaaatgatg gaaatcgttc agcaaaaaca gctggcacca
    45001 aagatttttg aaatgacatt gaaaggtgat ctagtaaaag aaatgcagca accaggacag
    45061 ttcttgcata ttctcgtgcc gcgtgcagac ttgctattac gccgaccgat tagcttgaat
    45121 catatcgacc acgaaacaaa tacttgccgt atcatttatc gggtggaagg tgaggggact
    45181 agagtcttct ctactctttc tgccggagac catttagatg tcatgggtcc tttaggcaat
    45241 ggttttgatt tgtccaatct tcatacagga gacgaagtat ttataatcgg tggaggaatc
    45301 ggtgtccctc ctctatatga gttatcaaaa cagttagtcg aaaaaggaat taagccaacg
    45361 cattttttag gttttgccac acatgaagtc gtttattatg aaaaagaatt taatcgtcta
    45421 ggagaaacaa gaatcgctac tgacgatgga acatacggta tgcacggaaa tgtcggtaat
    45481 ttattgttag gaacgaagac ggaacctaca gctgtttttg catgtggttc aaacgggtta
    45541 ttgaagacag tggaacagct gttttcttcg catcaaaatg tccagttatc attagaatcc
    45601 cgcatggcat gtgggatagg ggcttgctat gcttgcgttt gtcatacgcc ggaagatgaa
    45661 acaggaacaa aaagtgtgaa agtttgtgac gaaggaccga tttttaaaat aggagaggta
    45721 attatatgaa tgagaatcct ttagcggtca aacttcctgg cctagaatta aaaaatccta
    45781 tcatgccggc aagcggctgt ttcggttttg gcaaagaata cggaaaatac tatgatttga
    45841 atcagcttgg atcgatcatg gtcaaggcaa cgactccaaa tgcccgcttt ggcaatccca
    45901 cgccaagagt ggcggaaaca ccatctggca tgttgaatgc aattggtttg caaaatcctg
    45961 gtctagacgt tgttatgcat aaacttcttc cagaattaga ggagtacaat gagttaccca
    46021 tcatcgcaaa tgttgctggt gcttgtgaag aagactatgt agaagtttgt agcaaaattg
    46081 gcgaagcacc aaatgtgaaa gcaatcgagc tgaacatttc ttgcccaaat gtcaaacatg
    46141 gcggaattgc ttttggaaca gattctgatg ttgcttttca attaacacaa gcagtaaaga
    46201 aagtttcttc tgttcctgtc tatgtcaaat tgtccccaaa tgtaacagac atcgttccaa
    46261 tcgctcaggc aatcgaagct ggaggggcag atgggtttac gatgatcaat actcttcttg
    46321 gtatgcggat tgaccttaag acaagaaaac cgattttagc caatcaaaca ggtggactct
    46381 ccggaccagc aatcaagcct gtcgctattc gtttgattca ccaagtagca agtatatcca
    46441 gccttccaat cattgggatg ggcggcgtgc agacagtgga tgatgttctt gagatgttta
    46501 tggctggagc aagtgctgta gctataggga ccgcgaattt caccgatccg tatatctgtc
    46561 ctaaactaat taaagagctc cctgtgcgaa tgagcgaact aggcatcgaa tcgctggaaa
    46621 gattaatcaa agaagtgaga gaggaacgtg aacgatgaat caactagacc aacgaccaat
    46681 tattgcatta gatttttcaa ctaggcaaga ggtagaagac tttcttcgat ttttcccgaa
    46741 agaagaaaaa ttgtttgtga aaatcggaat ggaattgttc taccaagaag gacctgaaat
    46801 cgtacgttat ctaaaagagg ctggtcataa tgtattttta gatctgaaac ttcacgatat
    46861 tccgaatacg gtcgaaaaag caatgcgggg attggcaaag cttggtgttg atctcacctg
    46921 tgttcatgcc gctggcggta ttcgtatgat ggaggcggca atgcgaggat tagaagaggg
    46981 gactccagaa ggtggaaaac gtccgctact tctagctatc actcagctta cttctacaag
    47041 tgaagaagaa atgcatgccg atcaactaat cgaagtttct ttagaaaaaa gtgtgatcca
    47101 ttatgctagc tgtgccaaaa aagcaggatt agatggtgtg gtttcttctg cttgggaagt
    47161 agaagcgatc aaagaaatgg caggagacga atttgtttgc ttaactccgg gtataagacc
    47221 agaaggaaca gtcgcaggag atcagacaag agtagtcaca ccttctcagg caaaaaagat
    47281 cggctcaact tttatcgtta taggtcgacc aatcactcag tcaactaatc cttataaagc
    47341 atatcaaacg attcaaacag aatggagcta acctaaaatg aatgttgaac aaagtatcgc
    47401 aaaagactta ttagaaattg aagcagtatt tttaaatcca agtaatcctt ttacatgggc
    47461 aagtggaatc aaaagcccaa tttactgtga taaccgaatc acgatgagct atccaaaagt
    47521 ccgaaaagag atcgcaaaag gattagcaag caaaatcaaa gaagcttacc ctgaagtaca
    47581 agtgattgct ggaactgcaa cagcaggaat ccctcatgcc gcatgggtag cggaaatact
    47641 ggatttgcca atggtctata ttcgaagtaa ggcgaaagat catgggaaag gtaaccaaat
    47701 cgaaggacgt atatttgaag gtcagaagat ggttgtgatc gaggatttga tttctacagg
    47761 cggaagtgtc ttggaagcag ctgaagcagc aaaaagagaa ggtgcggata tccttggtgt
    47821 tgcggctatc tttacgtatg agttgccaaa aggaaaagca aatttcgaaa aagccgaaat
    47881 ccctcttatg acgttgacca attattctgt attgattgaa gcagctttag aagatcgtta
    47941 tatcgatgag caagaattaa ctctgctaaa agaatggaaa aaagatcctg aaaattggca
    48001 gatttaagcg cgcttgatga agatagagaa atccgatttg tgtctccaga atcatcaatt
    48061 ggaatagcaa aaatccaaaa actgattgcg agaagcatct tttcatcagg tatgaaaaga
    48121 aacttctatc gtgatcagtt tttgattttt ttaaaattca tttttctaag actggttagc
    48181 agaaagaaga gaataatctc ttctcttttt tctattatat atagattttc tctatttttt
    48241 ggtaagggag ctgtttcaaa aatggtaaag agcggaaatg ttgcgaatat cagttattta
    48301 atgatatgat attcggaaaa agaaatctca aagggaggta acttttatgg ggttgaatga
    48361 atttatttta ggattgaaca atttagagac gatcacaagg gcacctggat tttttaaata
    48421 tacagagcat acagttgcag cacattcgta tcgtgtagca tctattgcgc aagttctagg
    48481 agacattgaa gaagcgaatg gacaaccgat cgattggaaa ctgctctatg aaaaatcatt
    48541 gaatcatgac tacacagagc gttttattgg tgatatcaaa acgccggtga aatacgcaag
    48601 caaagagtta agagggatgc tgcaaacagt tgaagaaaag atgacggacg aattcatcaa
    48661 ccaagagatt ccagctgagt tccaagaagt ttatcgccgt cggttgttcg aaggaaaaga
    48721 tgaaaccgta gaaggagaac tattagccat ttcagataag gttgaccttc tttatgaatc
    48781 ttttgatgaa atcatcaaaa ataacccgga aaaagtttat aaggagatgt tcattgaggc
    48841 agtgactacg attaaaagct ttgaacatcg gccttctgtt cagtatttct ttaaagagat
    48901 atttccggaa ctattgaacc aggaatttta tggaaaagag gcgtttttag aaaccgtctc
    48961 aacgattgta aagaaagaag aaaaataaaa atgatatgag atgcaggggg aagtatagtt
    49021 gaaaaagaat atggatgtcg aatggggcta ttctggagac aaaggtccgg aaaattgggc
    49081 gagtttatgt gattggtttg cgagaggtgc ggaatttcca ttgcagtcgc ctattcattt
    49141 gaccaagggg gaagaaacca aaatagaagg agacacgctt tcctttcatt atcaaaagca
    49201 acggtttact gacaaggaat tcaaaaacac gattcattta gtaccttttg accaactcag
    49261 ttatgtagag ttcaagaaag aacgctatta tttgacagat attcatttcc acttgccttc
    49321 tgaacatatc atcaacggaa aacaggaaga tattgaattt cattttgttc atatgaacag
    49381 caaaaaagag aatctagttg tgggtgtcat gtaccagcta atggtacagg aaggttggct
    49441 gtataatcaa gaaaatgggg aaagttggaa cttagaaaaa catgagcatt gggtaaatcc
    49501 ggatgtgttc tttccggagc aaaaaagcca tttccattat attggctcat tgacaactcc
    49561 gcctaccagc gggccaatcc aatggtttgt aatggatcat gtaggaaaac tgaaccaaga
    49621 gtttcttctc cccttcgatg gtcagtatgc tcgaccgaac aaccgaccaa tccagccctt
    49681 gaatggaaga gaaatttatt atttcgagga gtttgagcaa tgaatattca gcagatgaaa
    49741 tacgtggtcg ctgtagcaaa caatggtagt ttcagagaag cggcaaagaa aatgtttgtc
    49801 tcccagccaa gtctttcagc tggtatcaaa gaattagaaa ccgagttagg gatcacgctg
    49861 tttactcgaa cgaatcgagg ggcatattta acagaagaag ggcaagactt cttaaatcgt
    49921 gccgagaaaa tattggtcca gcttgataca ttagaaactc actatctaac gagtgaaaag
    49981 agagacaatt tttcgatcgc tgcccagcat tatgatttct taggtccttt gaccgcacag
    50041 ctactcgagg aattcaaaga cgagatcaaa caatttcgga tcatggagac gacaacagcg
    50101 agagtgatcg aagaagtcaa agagcagcac agtgagatcg gcattattta tatgaatgag
    50161 cataatcaag ctggtatcag aagatattta caacaaggag agctaagtgg ccgcagcatt
    50221 ggaaaattca aaacgcatat ttttttaagg caaggacatc cattagctga acacgcagag
    50281 atcaccaaag aagaattgtt atcttatcct caagttcgtt ttacacagga tggaaataat
    50341 ttcccgtatt tttatgaaga ccttatcgag atccctgatc aagaaacagt gatttatacg
    50401 agtgatcgag gtactttgat gaatatcgtt cttgaaactg atgcttacgc ttcaggatct
    50461 ggtattgtga ttggagggat tcgcgagcac ttgcggttaa tccctttggc agaaggcgaa
    50521 ctaaatgaat tttatatcat ttattcggcg aaacgtccgc tcagtgaaat cgctcaaaga
    50581 tttatcaaag agcttactcg gttactggac cagcagagct aagaaaagca gatgagaacg
    50641 ctgtttattg aacaccgttg atcaaaaaag aggggttgtg acagaatttt gtcacaactc
    50701 ctctttttgt agcaaacaat ttataactaa ttgctgttgt gggaaagtac gcaaatatga
    50761 ttctagaaac actcattgat tacctgtttt gtttcatagc tgtaattttt tcttcttctg
    50821 gtgtcacgat aatcgtcttt tggttttcat aaataacata accaggcttg gcgccatttg
    50881 gttttcggat atgctttacc tgtacaagat caaccggcac ttgggcagag tatcggtatt
    50941 ttgaaaaata ggcagctaac tcggcagctt ctgtaattgt ttcatctgag ggcttgtcac
    51001 ttttaatgat gacgtgcgaa ccgggtatat tttttgcatg aagccaatag tcggtttttt
    51061 tagctgtctt cattgtcagc tggtcatttt gaagattgtt tttaccaaca agaatgagcg
    51121 ttccgtcaga agaaaagtat tgatcaggct gagatggttt cttacgtttt tgttttttta
    51181 agttcttctt tttcaggtat ccttctgaag tcaattcttc tttaattgct tcgatatcca
    51241 ttgggccggc aatttccagt tgagataaga cagattcaag atattggatt tcatctttgg
    51301 cttcttggat ttgttcgcca atcagcttaa cagcgttctt cagcttttgg tatcgatgga
    51361 aatatttctg tgcattttga tttggtgtca atgccggatc tagtgctatt ttgattggcc
    51421 gatcttcttc ataataatta ggtaaaacaa cttcttttgc gccgcgtggt acttgtgtca
    51481 gaaaagtagt aagtagttcg ccatttctac ggtaattctc agcgttttcg gattctttga
    51541 gtgtttgttc acgttttttc aatttatttt tatttcgttt tagttcattt tcgatttttc
    51601 gaatcagttc tccgccttgt tgttttgccc gatctttctc tgctttttcg tgataatagc
    51661 tatctaataa ttgactgagt gttggataag ctgttacagc agatgcctgt tcggacaata
    51721 cctgataagc aatcggtgtg aaaaaatctt tattttccgt ttcgtaaaaa gtaggaatag
    51781 gctgatggct gatggctgag aaaaattcgt cccatacaac catcttttca ttaggacgtt
    51841 ccagtaatct tttggtcagc tcttgagcga tatcgaaacc gattccctga aactgacgtt
    51901 ggattgcttt tggatctagt tcagtttggg aaagccgctg aaagattttt tctttctcgg
    51961 agctaaatgg gttcaagacc tcttgttttg gcggagcaac atattctaca ccaggaagca
    52021 aagaacgata agtgttttga gagcttccaa tgtgtttgat cgcatccagt atttttccag
    52081 tttctcgatt aactaagacg atcgtactat gacgtcccat taattcaacg atcaatatga
    52141 tattttgtag atcacccaac tcgtttcgtt tagcaaagtg gaaatggatc actcgatcat
    52201 tttcgatttg ttcgatgtct tctaaaatag cgccatccaa atattttcga agcatcatca
    52261 cgaagttagg cggattatca ggattctgat aatcgatttg ggtaatctgt acacgagcat
    52321 aacttgggtg cgcagataat aataatcgat ggtttttgcc gcgtgaacga atcaccagca
    52381 cgatttcatt ttcataaggc tgatggattt tcgagatccg gccagatagt aacgtttcac
    52441 gcaattcgtt gaccatcgcg tgggtaaata caccatcaaa ggacatggtt cattcctcat
    52501 ttcttttcat aagtatattc attataacga aaaaaagaag aaaaaccaat ttggccgaat
    52561 agtaaagcaa aagtctagaa aaatcttgga ctaattacat aaaaaacagt gtttctatcg
    52621 ttgaaatcca aatttttagg tataataaaa aataggagaa aaagtagaaa agaaggtgtt
    52681 tgttatttgg gaagtagtta aatcgagagt acaagaaatg aatgaacatt tctcagtgtc
    52741 attcgcagaa aatccaagta agtattttcg acgtcttgtt tttctgctca tcttatcatt
    52801 gctgttaaca gttgcaatgt ttttattgcc ggaaaaaatc cgagaagagc aagtaaatag
    52861 tctcgtttat tcgtccatac caaccagcaa attgaaacct tttgattaca gcaaagctga
    52921 tcagaaaatc aaacaaagcc gggcgatatc ggtgatgttc agcaaaccga acgggaaaac
    52981 ctatcaggac atgcttgatg tttttaatga tcctgagctt atggaagaat tgaatcgacc
    53041 gatcttttat tatccgatcg tttatgatgt acatgaactg gaacaaaaat ataacatacg
    53101 aacggatgaa gtgacattta ttttctttga tggaggaaaa gaagcaaatc ggataactgc
    53161 gggtaaggga ggaataactg attttgataa ggagttgatc cctgaactga atcgacttcc
    53221 gttagccaat atcaaacaat tagaagaaga attggataga acgggagtaa cttcccaaaa
    53281 ttccgagatt gctaattgag acattggcgc gatgaaacgg tgggtctata tagcgctatt
    53341 tttaattatc agaacaagtg atgtttgatc ttcaaaataa caaataaaaa attaaaaaat
    53401 atagttgacg aaattcaaaa attcgatttg acttaaatca attcttaagg aaagggtgac
    53461 ctgtaatgaa cttatcaaaa cgtatttcag cagaaaacaa aaaaaattgg cgcagctggc
    53521 gtagataagt tgtattaatg gtgagacttt cccatagata caacttttta gagtgcattt
    53581 ctaaagcttg tatctatgct agacatgaac attgactgcc gcatagatta gaatctatgc
    53641 ggttttttgt gtaaagacaa tgaccgcttt ggccattgtc tttttttgta gactggatac
    53701 ttgcctgatt ataataaata aaaagattga ctttgcagga ggaaaaaaat gaaaaacaaa
    53761 cgattaataa cagttgtagt aattatttta gtttatttag caggtgcatt tatttatgga
    53821 aaagcctcag gcgaaaaaga aagtacttcg acgaaccaga caaaaaaaac aacagttgtt
    53881 ggggtattgc aatacgtgag ccatccggca ttagatgaga tttatcgagg aatcaaagat
    53941 ggtctgaaag aagaaggatt aaaagaagga gaaaatcttg agatcaaatt tcaaaatgga
    54001 caagccgatc agagcaagct agccacaatg agtcaacagc tagtacaatc tgatccagat
    54061 gccttgattg gaatcgcaac acctgccgct caatcattag caaacacgac ttcatcgatc
    54121 ccagttgtgt taggtgctgt aacggatcct gtgggggctg gattagtcgc ttctttagag
    54181 aaacctggtg gtaatgtaac aggtgtttct gatcagccgc ctgttacttc acaaatcaag
    54241 cttgcttctg atttgttgcc aaatgcaaaa aaagtcggaa tcttgtatgc ttcttcagag
    54301 gataattcaa aataccaagt agcacaagca gaagaagctg caaaaaaaga agggttagaa
    54361 tcagtaaaat atgcggtgcc ttccactaat gagattgcac aaacggttca agtgatgagc
    54421 cgacaagtcg attttatcta tgttccatta gataatacca ttgccaatgc gatgcaaaca
    54481 gtggtaaaag aagcaaacaa agcaaatatc cccgtcattc catctgtgga tacaatggtg
    54541 gaacaaggtg gactagcaac aatcgggatc aatcaatatc aattagggct tcaaagcggt
    54601 aagatggcgg cagaacttgc gagtggaaaa gaaaaaccgg aaacgacgcc tgtttataca
    54661 tttgatcaag gggatacagt gatcaatcaa tctcaagctg atcgcttagg aatcattgtt
    54721 ccccaatcga tgaaggaaaa agccaaaatc attacagatg actcgcagca agaaacatct
    54781 aaggaggatg acaaatgatc gtatcagcta tttcacaagg catgctttgg gcaatattag
    54841 gattagggat tttcatgact tatcggatct tagactttcc tgatatgacg acagaagggt
    54901 ccttcccatt aggtgctgct gtctgtgtga cagctattac tcatggggta gcgccgattg
    54961 tagctacatt attaggcgta ggtgctggca tgatagcagg actcgttacg gggttacttt
    55021 atacaaaagg aaagataccg gttattttag cagggatttt agtgatgtca ggattgaact
    55081 cagttatttt gtttgtgatg cgaacaccaa atctttcttt attgaatcat ccgattctac
    55141 aagacagctt ccatcgcttt gggttacctg attactttga cacagtcctt cttggcttca
    55201 tctctttggg catcttgatt gctgtactgc tattcttctt caatacagat ttgggtcaag
    55261 gctatattgc gacaggagac aacgaaacga tggctcggtc gttagggata aaaaccgatc
    55321 gtatgaaaat tttaggttta actttgtcga acggtgtcat tgcattatcc ggtgcgctga
    55381 ttgcccagaa cgacggatat gcagatgtaa ataaagggat tggcgtaatc gtcatcggtc
    55441 ttgcttccat catcatcggt gaagtgatct tccaagaatt gacgctagca gaaagattga
    55501 ttgctattgt tgtcggcagt atcatttatc agctattgat tttagtagta atcaaactag
    55561 ggtttgacac gacttatctg aagttgttct ccgctatcat cttagctatt tgtctgatga
    55621 tcccgcaatt gaagaaagca ctgaacttaa aaacgggttt tgagaaggag gcatagtaat
    55681 gactgatata ttgacaatca aaaatggcag aaaagtcgta aacaatggaa tgaatgaaga
    55741 gaaagtacta ttggatgaaa ttaaccttac aatcagagaa ggggacttca tcactgtcct
    55801 tggcgggaat ggtgctggaa aaagcacact gttcaatacg atcgctggta cgcttcaact
    55861 cagtcaagga tcgatctctt ttaaagatca gctgatcaca aaagattcag aagaaaaaag
    55921 agcacgattc ctttctcgag ttttccaaga ccccaagatg ggaacggctc ctcggatgac
    55981 agtagcagaa aatttgctac ttgcacaaaa aagaggtcaa aaacggaaat tccgtttacg
    56041 taacttgaaa aatcaaaaag aagatttttt cagactatgt caagaagtcg gtaatggcct
    56101 agagcaacac ttggatactc cagcgggtga attatctggt ggtcaacgcc aagcattaag
    56161 cttgctgatg gcgacgatca cagctcctga gttactatta ttagatgaac atactgcagc
    56221 tttagatcct aaaacagcta aagcattaat gcgattaaca aatcagcgga tcaatgaaca
    56281 aaaattgact tgtctcatga tcacgcatcg aatggaagac gccttgaaat acggaaatcg
    56341 tctgatcgta ctccaaaaag ggaaaatcgt tcaagatatt tctgaaaaag aaaagcaaca
    56401 tttgacaatg ggcgaccttt tgcagttctt tgaagaagta gtggattgat ttcgacagaa
    56461 aaattccttt cagtagaagg acttgaaaac tcattgacat cttcctttga ttcatcctat
    56521 acttaaaaca ataaacaatt aaacatattt gggtgttttg taggatcacg tagtcaatga
    56581 ttttaacaat taaatagaat attctttgct ctgacaagta aacgatgaga aaagaatttg
    56641 ctactttgcc acctagacgt ttcgtacttt ttcgtatcaa acgctaagtg gcttttttta
    56701 ttgaagtaag aacaaaggag gaataagatg atttctggac aaaccaaatt agctgggctc
    56761 tttgctgatc cggcttctca cagtttatcc ccattgatgc acaatactgc ttttgaagca
    56821 aacaacatcg atgcggtgta tttagctttc caagtaaatc caatgaattt gaagcaagca
    56881 gtcgaaagta ttcgaacttt tgatatgtta ggtgtaaatc tttcgatgcc gaataaaaca
    56941 gcggttattc cttatctgga tgaggtaagc caggaagcgc aattgatcgg agcagtgaat
    57001 acgatcgtgc acgaaaaggg tcgtttgatt ggctataata ctgatggtgc gggcttcatg
    57061 caatccgtgc aagaagctgg gatttcgatc aaaaagaaaa aaatgactct actgggagct
    57121 ggaggtgcag caaaggcagt cactgttcaa gcagcgttag acggcgctga ggaaatcgta
    57181 gtttataaac gaaacaacca aacattcgct caagtaaaag aaacattcga acaactcagc
    57241 tatcgaactt cttgtaagat aaaagttcgt gactttgccg atacgcatca attaagaaaa
    57301 gacttgaaag aaagctgtct tctagtcaat gcaacagata tcgggatggg aaagaaaatc
    57361 aatcagtcac cgctcttaga tataagcatg atgcatgaga atctagcggt ttttgatttg
    57421 atttatgcac ctagagaaac acgtttatta aaagaagcaa aaaaagtagg agcaaaagga
    57481 tacaatggac ttggcatgtt gatctaccaa ggagcaatcg cgtttgaatt atggacaaag
    57541 gaaaagatgc cgatccatgt gattgaaaag ctgtttgatt aaaaaaggat aatagataaa
    57601 gatcttttat tctcgcataa acggtctcaa gaaaagtaat cctttatgta tcgaagcatt
    57661 tatttcgtta ttttttatta aattatcaaa aaatgatagg cttttgtcga ttggttatcg
    57721 tatcctttat ttatcagtaa gaaacgagga ggaaccacaa tgagtcggat ggatcgctat
    57781 aaggacatcc ataagaaggc gaaacctctg aagcgggata cggggagtat ttttgctaga
    57841 agagaacgaa aacgaacgcg tatggaaaat gaggaagatg ctacccgtat ttatgaaaga
    57901 gagcagcatt catttgaaca tttgaaccaa tacgagcaac agatatacag agatgcacca
    57961 agagcagaag aacaacaaaa aaataaaaaa tttttcaatc ggcaaaagaa gaacaaaccg
    58021 ttaaaacctc gaagaaagcg atcgtggaaa aaaatcattc tatcgatttt gcttgttttg
    58081 atcctttatt caggtatctc attttttatt ggtaaatatg tagctgaaca tgacacaagc
    58141 ttagaggcag cgacttcaga aacctttcat gggcaaaaag cgacgaatgg tgcgcataat
    58201 attttgatcc ttggaagtga tacacgcgga gaagatgccg ggcgagccga tacgatcatg
    58261 gtcttacagt tggatggtcc ttcccataag ccgaaactga tttcttttat gcgtgacagc
    58321 ttcgttacga tcccaggggt aggacaaaat aagatcaatt cagcttatgc atacggagga
    58381 gccgatctag tgcgtcaaac tttagtagaa aattttggaa tcgattgtca atactatgcg
    58441 aaagtcgatt tcaaatcgtt tgaaaaagtg atcgatgcct tattcatgaa cggagtgaag
    58501 atcgatgcag aaaaagatct gaatctggat ggtgtagata ttaaaaaagg gggccagaag
    58561 atggatggac atgttctttt gcagtacgca cgtttccgaa tggatgaaca aggagacttt
    58621 ggccgtgtca gacgccaaca gcaagtaatg aacgctattt tcagccaatt gaagaatcca
    58681 ttgaatctga tccgtgcacc ttatgcagct ggtaaagctt taggatatac atccacagat
    58741 gtcactgctt ggttcttgac gaaaaacctc ttttcgattg cacgaggagc tggtggcatt
    58801 gatcgaataa gtgtgccagt agacggttcg tggaattatg ggcaaagtga ttatgctggc
    58861 agtattcttg aaattgataa tcaaatgaat caatctgcta ttacagattt tttgaataaa
    58921 tgatcataaa aaagatcaag aagaagctgc gcaaggcttt tgtcatgaat caatcaaacg
    58981 attcactcgt aaaaaacgct ttcttatggt agatttaacc aagagaggag ctgtttacat
    59041 tggatatcta tctgaacttc aaaaatgagt cgcgtgaagc catcgctttt tatgaaaaag
    59101 tttttcagac tgaagcatca ggtatcacca catacggtga aatgcctgga atagaacaaa
    59161 tgaacttgcc agaagaagca aaaaatctaa tcacgaatgc acggctgaac atttatgata
    59221 cattagttat gtttgcagat acgccagaag gaattggtcc tgaattagtt gtgggaaata
    59281 atgtttcttt agtcatccag acaagaaatg aagaagaaac gaagcgccta tttgaaagct
    59341 tagctgaggg tggtaagatt gagatgccac tggatgctgt tccgtgggct cagttgtatg
    59401 ggatggtaac tgatcgattt ggcatcaact ggcagattaa ccaagagtga cagctaaaga
    59461 tgaatatttt ctggaaacat caagcagcaa acggatcatc gtttgtttgc ttgatgtttt
    59521 tgtgtctatt tcgactatac ggtatctttt ttttattgcc agatgcgaaa atatgttcca
    59581 taatagagaa gtccgcaaaa aattaagtaa cggaggtcag aagatgaaga cggtgatact
    59641 agctgaaaaa ccttcacaag caaaagccta tgccgaaacc ttccaacagc aaaagcggca
    59701 tgaagggtat tatgaaatca gcgatccatt gtttgctggt gaagtaacca tcacttatgg
    59761 ttttggaaat ttggtagata tggttgctcc aggagcttat gaagagcgtt gggcaaaatg
    59821 gtctttagaa aatttgccta ttttcccaga aaccttccgt tacgaagttc caatggacaa
    59881 acgtgcacaa ttttcgatcg taaaacgaga attgcagtca gccgatacca tcattattgc
    59941 aacagatggt gatcgagaag gtgaagccat cgcgtggtcg attattcgac aagcaaacgc
    60001 attttctaag gaaaagaact atttacgttt atggatcaat tctcttgaaa aagaagcaat
    60061 ctatgaaggt tttaagaatc tccaacctgg aaagaactat tttccaaaat ataaagaagc
    60121 gcaagcaagg cagaacgctg attggctgat tggaatgaat ggaagtccat tatatagctt
    60181 gctacttcaa cgaaaaggga ttgatggcag tttttctctt ggtcgtgtac aaacaccgac
    60241 actctatatg atttatcagc tgcaagaaga aatcaaacac ttcaaaaaag aaacgtactt
    60301 tgaaggagaa ggtttaatta cgacaaacaa agggcagttt tctggaaaaa tcgtaccaaa
    60361 aaaagcattt aaaacccaag aagagttaac gaaggaaata gaaaaacttg gagcgcattt
    60421 aggtaagcaa aacggacgga ttcttgaagt tacgaaaaag gaaaagaggt tgcatagtcc
    60481 acgtttattt tcgctatcta gtttgcagac aaagatgaat cagctaatga aagcaagtgc
    60541 caaagctaca cttgatgctg ctcaaggatt gtacgaaagc aagtttctaa gctatccaag
    60601 aacggattcc ttttacatta cagaaaatga gcatcagtat ctggttaaac atctgcaaaa
    60661 ttataaaaaa tttttaggaa tagaagaagt acagacaact gagatcaaag caaagaaacg
    60721 atatgtcgat gcgaaaaaag ttcaagaaca tcatgcaatt attccgacaa agacgattcc
    60781 gactcctgca cgctttgcga agctttccaa attacagcaa gcaatctatt tgcaagtttt
    60841 gcgcactact gtggctatgt ttgctgcaga ttatatctac gaagagacga ccgtaatgac
    60901 gggcgtacag caattaaagc taaaaagcat cggaaagatc ccattacagc aaggttggca
    60961 ggaaatctta cgcatcaagt caaaaaagaa agaagctcag actcttcctc ctatcgtaga
    61021 aaatgaagaa gcagaagtag aactgaaaag tatggagaaa gaaacacaac ctccaaaacc
    61081 ctataccgaa ggaacgttga tcacagcaat gaaaactgcg ggaaaaacgc tggataatga
    61141 tgaagcgcaa gaaattctca aagaagtaga aggaataggg acagaagcta cacgagccaa
    61201 tatcattgaa aatcttaagc agaagcatta catcgaagtc aataaaaacg aaataactgt
    61261 tacgccaaaa ggaatcactc tttgtaaggc agtagccaat gaaccattac tgacgagcgc
    61321 agaaatgact gcgcgctggg aagggtactt gagaaaaatt ggtaaacaag aggggacacc
    61381 atctgttttt ttagagaata tcaaaaaatt catcctacat ttattggcag aagttcctaa
    61441 tcaaatcgac aaggtagact tttcagatga gattagcggg acacgtcaga taaaagcgat
    61501 ggagaagaaa aacgatcaat taggaagatg tccaaaatgt aaaaagggaa tagtcatgct
    61561 ttatcctaaa atcgctacat gcttgaatcc ggaatgcgac ttcaaattgt ggccaacagt
    61621 agctaaaaag aagctgacta aaacgaatct cagagatttg ctttcaaaag gaaagacaag
    61681 taaagttgtc aaaggtttta ctggtaaaaa agggaaattc gatgcagttt tagtattaaa
    61741 agaagatatg acaatcggtt tttcttttcc atggatcgaa aacagtggaa caaaagcagt
    61801 tgatggaaac aaagaaacat caagaaaaaa taatgaaaac gaagtagagt aaatgaaaac
    61861 aatgaaatag cggaatattt attccgaaaa gtgagaatat aaataccaat aaaactaaaa
    61921 aatatcagtg aatcaagcaa aaacgttggg gtaggctgat tttatataga tagcaaggag
    61981 tttttttatt tgaaaaaagt gcattcattt ttaaattatc ttatgggagc aatcacgatt
    62041 gtggctgtgt accaagcatt tctaaagtat cctgattacg ggacgaagtt gttgtcattg
    62101 acgcacaatc aaacagcata ttcaccaacg ttgattttat cgactttgac tgcaggagct
    62161 aaaagcgcta cttatttttt tcataaaacg acaagcatgc taaagcgaaa gaaacagcga
    62221 aaacaattgt tggtggtggt agcggctatg atcattattt attttctacc agttattaca
    62281 caagtatttc atcaatattt tggttaagaa tacgagagtt tgtgacaaaa gtcatgtcac
    62341 aaactttttt ctttgtcatt ttttcgtaag aaaaagcaaa ataaaagtat atacattgat
    62401 taaaagtata tacttggata taatgtactt actatagaat gagaatggta tagagggtgg
    62461 cgaaatatga aaaaaatgaa aaagtataaa attagaaaat ctggcaatag cgatgtaaca
    62521 actatcccac cagaagtaaa agaattcatg ggtgtgcaga caggtgacgc aatcagttat
    62581 gtttttcaat ctgatggttc tgtacgaatg atcaaagcac aagaagaacc tgatattgat
    62641 tcattagttg attcgatcat gaatcaatat gaagacgcgt taaaagattt ggttgattta
    62701 tgaggtatct ttcgactaaa gaaattatca aaatcaacgc gaaagttatt ttacgtcact
    62761 cgccaggcga aatgatcggt gtaaaagatg caaatgcatt agatatggcc gtcaaacagc
    62821 cttcacaagc agtattcaat caagaactct atcctgaaat ctatgaaaaa gcggcgattt
    62881 tagcaattaa tttagctaaa aaacatcctt ttcataatgg caataaacga actgctcttg
    62941 ttgccatgtt gttgtttctt caattgaata attgtccagt tgctttttct cgtcaagaag
    63001 ctgttgattt tatcataatg attaccacta gttcattgga tttcgattca ctaaagtcca
    63061 agataaccag ttatttacga caaaccgcaa taaaatgaac gaattaaaaa ctttatttct
    63121 caattagatc agcatgtcat taaggaatat gctgattttt ttatgtttaa tcatacaaaa
    63181 tagttttttc ataaaaatat ggaaaatatg gattaatttt gaaataattg atttaaaagg
    63241 aatacaaaag agtgaatagt aggaaatagt ggtttagaac tagtgggctg attttttata
    63301 tattttagtt tacataatat atattataca aagtagattt aaaaaatgat aaacctctct
    63361 cgaacggttt tttatcaaaa atcgtcattt ttccatcaaa atctgcttat gcaaaattat
    63421 aaaaaaattt tgcagttttt cttacttttt ttgtcgttta attgaatgat aaaaaccagt
    63481 ttctttattc agttaatcaa atatgaacga attagatatg aatcattgta tttgccgttg
    63541 cggaaggatt ttttaattaa ccacagataa acattgataa cgattcgctt attgtaatca
    63601 acagattaaa tttcatatgt tcatatgtac ggatacattt tcggaccgat taattttaac
    63661 cattctgttt atttgcttac ctattagata tcaataaaaa actgcttaac agctatttca
    63721 gctgttaagc agttttagga tttttagttc atattcattg tttcttataa tacagtgttc
    63781 aatacttctc ttaaagcact tgttgatttg ctgaacattg ctttttcttc ttcgttgatt
    63841 gataattcaa caacttcacg aacaccattt tcgtcaacga ttgatggcac acctgtaaag
    63901 atatcttttt cgtcgtattc accagttaaa taagcagata caggcaatac agcttgttcg
    63961 ttattcaaga tagcttttac gatacgtgca gtactcatac caataccata gtaagttgct
    64021 tttttacgat caatgatctc ataagcagca ttacggactt tatcagcaat cacatctaat
    64081 tcatcttggg caatacgatg gtctttttct acaatttcaa acactggttt accaccgaca
    64141 gttgtatgtg accatgcagc aacttctgaa tcaccatgtt cacctaagat atagccgtgg
    64201 acgctgcgtg ggtcaacttt taatttcaat gcgatttctt tacggaaacg agttgtatcc
    64261 aatgttgttc cagtaccgat aacacgtgat gttggcagac cagattcgtt ccaagcgata
    64321 tatgtcaaaa tatctactgg gtttgaagca acaacgataa taccgtcgaa tcctgatccc
    64381 atgatttctt ttacgatttg gcgcatgatt gacgcatttg ttttaactaa atctaaacga
    64441 gattgaccag gtttttggtt gataccagct gtgataacaa cgatatcagc atctttacat
    64501 tcttcatagc cacctgacca tacagccaca ttttcatcgc cccaagccat accatctaaa
    64561 aggtccaatg cttccccttc tgctttttct tgattcacat cgatcaatac taattcatta
    64621 gagattcctt ggttgatcat tgcataagcg atacttgttc caacaaaacc tgtaccgacg
    64681 attactactt tacgacttgt ttttttcatg aataaacagc tccttttcat aactatttgt
    64741 tactttcatg aaaagtatag tcttgtttat tcattttatc aacatgttaa ttataatagt
    64801 tgttattata atttttgatg gaaacgaatt cctgaatacg cataacagat aaatgacaaa
    64861 tgtttacacc tatatcccct gataatacaa ccaaaagttt agaactgaaa ataaatccaa
    64921 aaaaattcgc tgcaacgata taataagaca gcaatcgcac ctaaaacaat tttccttcat
    64981 atgctttagt gaaagatttt cttcttaatg tttatttctc cattcattgg gagtacatgt
    65041 tgaatacttc ttgaataatt tgaataaaga agtcgtttgt ttatatccga tacgattagc
    65101 gatttcttcc aacgaaaaac tcgtttcttg aatcagttcc aacgcaaagt cgaatttttt
    65161 ctttagaacc agttcttgaa aggaagcatc aaaatacatt ttcaatttat tactaagata
    65221 gaccggattg tagccaaaat gagctgctgt ttcttttaac gtacaagaag taaaatgctt
    65281 atcgatataa tctaatactc taagcatctc attttctgcg catccatctg ctgatgaaaa
    65341 gctttgttgt tctaataaat gagtcaattc gatcagtaat agtgatgtat agagatttaa
    65401 cgaacggatc ttatgactgt atgtatcaaa ataaatcaac agcatatttt caatcaaatg
    65461 cgtcaaacga cttgtttttc cgccgcgaaa atgaatgaat tgtgtatgtt cccctttttc
    65521 ttttgatgca tttatcaaaa aagaagaaag tagattattt gtgcttgcca aatgattcaa
    65581 tatctctgta gataaggttt cttcttttaa taagatgttg attaaaatat cctcttgccc
    65641 tgtgtattcg attctttgag tagcttcttt atcaatgatc accacgtcac tttcttccat
    65701 ctctatcctt tctccattaa taatttgtaa acatgtaccg ctatacatat aattgatttc
    65761 aacaaaatca tgtgtatgct cgggaacttc cgcatatcga cggtgtttac tgatatgaat
    65821 atttccctgt tgaaatagat cccctcggtg gatttttggc ggtgtctgaa gatggtaagc
    65881 taagtttaaa tcattgatat tcattccttg ttcacgctgc agagtttcga ttgattcttc
    65941 gttacgcaaa aaaaatgtct aattcagcta gttccaattg actccctcct ttttgtaagc
    66001 ggtttctttc gcttattagt tcacgctgta ctgctattat atgcaaagct atttttggtt
    66061 tcataaagac tttctatggt tgggacatga acttcctgtg attccgctat tgagagaata
    66121 accacttcat actatatttt tgataagcgc ttacaaaaat gaaaggaaca tgcttatgaa
    66181 taaaaagatg atgaaatttt ctctgctgtc agtctctctt attttgactt ctgctggtgc
    66241 agtcacgtct gcaattccca gtatgtcagc tacttatgcc acgcgttctt tatctgctgt
    66301 tgaattatta acgactgctc cctcttttat ggtcactatt tttgttttga ttagtagttt
    66361 tattgctagg aaaatcggac aaaaacaaac tgtgatcatc ggattagtga ttgcatcgat
    66421 ttgtggtatc ctccccctct tctcacaaag ttacagtatt gtcttagctt caagagctgg
    66481 actaggtatt ggctttggat tgatcaattc tttggcagtc agcatgattg ctgcctttta
    66541 tcacggagat gaacgagcct ctatgattgg ttttcaaagt gcatttcaag gatttggtgc
    66601 agctttaatg acatttgttg caggacagct agtacagttc ggttggcaat ataccttttt
    66661 agtctacgcc atcagcttac ctattcttgt cttgtttgtt ttgtttgttc ctacacctga
    66721 aacaactgaa cttcaatcgc atggcacagc cccaacaaga caagtaatca aaacgaatcc
    66781 taaaatgatt agttatggta tttttctctt gctggtcatc gtggtatata atgctgtatc
    66841 gattaaatta gccacagtcc tgacgactta ttctctagga aacgaaacta atgcagcgaa
    66901 tatcttaaca atcatgcaat tggcaagtat ggctgccgga gtttgttttg gctggcttca
    66961 gacaaaagca catcgctata tgcttacact ttctttacta ctgatgggaa tcggctttgt
    67021 attgattgcc actgtgataa acctgtatgt gattgggttt ggtgcgatcc taacaggaat
    67081 ttctttttcg ttattcattc cttacttatt caaccaagta agtatccaag cgcccaagta
    67141 cgcggagagt ttcaatactt caatcttatt ggttggcgct aatttaggta ctttcattgc
    67201 accatatggt ttgctctttc tctcttttgc ttctcttggg agtaaaacac ttgctgtttt
    67261 cgtcaatggc agtatcttgc tgttgattag cgcgcttatt agccttctag tagtacacag
    67321 gacgaataga aagacagtga taagagtaga tgaagaaata aaagaacaat tgacaacaaa
    67381 ataaatttga tggaggtcgt gtaaaatgac aaatgaaaaa cataaagata gatggctttg
    67441 gtatcctgga gactttgaga tccgccatgg actgctacaa aatttccaac gggaagaacg
    67501 aggttttgac tggccagcgt actggtacat ggatgattgc catcggaacg tcaagtttaa
    67561 gagatattac tttcttgatc aaccttccat gtttaaagtg acgatccaag gagttgggta
    67621 tgtagaaatt aatggacaaa aacatccatg tggaaaatgg ctgacttgtc cagctggtaa
    67681 agcaaaaatt cgtatctttg taggacatac atcagggcta ccagcgatgt ttatcgaggg
    67741 agacgaagta aaatcagata ttggctggac agcaagtaat tttattgaag aatatccagc
    67801 tggctggagt ccgctttatg tcgatatcgc aaaagatcca aatcaaatct attatcaaaa
    67861 agaatgcgtc catccagtca ctgaaacgga gattggcgga ggaatcttat tcgattttgg
    67921 gcgagcagtg aatggctgtg tagaactaat atctctggat gaccatatcg aatctatcac
    67981 tctatgttat ggagagtccg atgtagaagc tatggatatc gattattgct actataagca
    68041 aataggaatg acaagaaaaa tgaaagctcg taaacgcgct tttcgctatt tgtttatacc
    68101 agaggtttct actggaatgg ttcaacttca agtttttcat gaatttttat ctctttcgaa
    68161 acaagctgct ttttcaagcg attcttcttt actgaatcag atctggtcag tatcagaaga
    68221 agccttcaag ttatgtagtg atttgttttt tatcgacggt atcaaacgag atcgctggat
    68281 ttggtctgga gatgcgtatc aatcattcat gatcaatcaa tatctttttt ttgacgagga
    68341 aatcaataaa cgaacgatat tagcattaag aggacaaaat gaaatcaagc agcatatgaa
    68401 tactatcgtt gactattcga tcttgtggtt gattggtatc gaaaaccact atatgatgac
    68461 gaaagactat gaatttttac gcatcgtcta ccctaagatg caatcattaa tgagatactt
    68521 gatggagcaa acgaatgaat tagggtttat ttatgggaga gcaaaagatt ggatatttat
    68581 tgattggtct gaaatggata aagaaggaac gcttgctgca gaacaagtct tattactgaa
    68641 agcctatcat tccatgatca cttgcggaga tatcttagct gaaacatatg gagagaacga
    68701 aaattatcat actcatctct atcaagaaaa atatcaacta ttgaaacaaa acctatttga
    68761 ctacttttgg gatgaagaac ttggcgcttt tatcgattgc tatgaatctg ggagaagaaa
    68821 tgtgacgcgt catgcgaata ttttcgctgt tttattcgat tttgctaaca aagaccaaca
    68881 gcaatcgatc ttaaagaatg tcttattgaa tgacactatc acacagatta ctactccata
    68941 tttcaaattc tatgaacaag atgctttatg caaactcgga cagacgaata tcgtctacca
    69001 aacgattctt gattattggg gagggatgtt atctcatgat gcggtaactt tctgggaaga
    69061 atacgaccct actcaaacag gaaatgaaaa gtacagtatg tatggagatc cttatggaaa
    69121 aagcttatgc catgcatggg gagcaagccc aatctatctt ttaggacgct attttatcgg
    69181 tttgtatcca acaaagccag gttatgaaga atttatgata caacctaatc tagattcatt
    69241 tgaaacactg aattgtacgc tacctatcaa agatggaaag atttcgcttg aaaaaacaaa
    69301 agataagatc gtgattactt ctgatagaac aggcggaaca gtgaaaatga atggtaaaag
    69361 ttatcctctt ctagcaaaac agccacttgt cttaacaagc tattcaaaaa taaatgcata
    69421 aaacaaaaaa ctgcttgcga catatcagaa gactttaaat cttcttctga tattgtccaa
    69481 gcaattttta ttttgaagtt tgcttaattc tgttctttag aaacaatgtt tgttcttttt
    69541 ccggcaaaaa gaaagctaga taatacgaca agtaaaaaga aagcgatgat tccaactgtc
    69601 aaggctattt gaccgtattc tcctagtttc ccaagtacaa gtcctggtac tagataatca
    69661 gtatcggcaa atgtagaaga agcgatttta agatctccta atactggaag gataaataat
    69721 ggcagccaac taatcaataa gctattgaaa gcagaaccta ataccgcccc tcttctaccg
    69781 ccagtcgagt tgccgaagac accagaagca gctccgcaga agaaatgtcc tactacccca
    69841 ggaatgataa ctgtagtttg caagcctatc atagcaaaca tggatagtgt tcctacaaag
    69901 aagctaacaa aaaagccaat taatacagca ttaggtgcat atggaaaaac gataggaaca
    69961 tctaatgctg gtttagaatc gggtacgagt tttttagcaa tcccttggaa tgctggaacg
    70021 atttctgcca acaccattcg aaccccttga aggacgataa caaacccagc tgtgaatgtt
    70081 ccagcttgga tcagtgcaaa gattacagcg ttgtctccat tgcttagttc tctttcaaca
    70141 aatccaggac cagctaacaa agcaagtgcg acatatacga tcgacatcaa gagcatgatc
    70201 gatacagtag aatctcgcaa aaagctgaaa cttttaggaa tctttatgtc ctctgtagaa
    70261 cggtctttgt ttccaaaaaa ctttccgatc catccactag aagcataacc gatatttccg
    70321 gtatgcccta acgcaacttg attgtttcca gtgatgttct tcataaacgg ttgacaaaga
    70381 gcaggcgtaa tagttaatag tgttccttcg aagaccccgc ctaataagat catccacaaa
    70441 tttgcagtaa accccgcgct tactaaaatg actgctgtta gacaagaaac ataaagcatt
    70501 gcttgacctg taagaaaaat gaatttatat cttgtgaatc tagcaagtaa aatattcacg
    70561 atcatcccta ctagcatgat caaagcagta ggtgtaccgt attgttgcaa agcaatcgcc
    70621 actactgctt cattgctagg aactactcct tgagtatgca gagctgtttg gaacatcgaa
    70681 gcaaaagggg ttagtgaatt actgattaaa ccagcaccgc cgatcagtac taggaatccg
    70741 acaaatgttt tgatagttcc ttggatcact tctgaaaatt tcttcttctg aagaacgaga
    70801 ccaagcagtg caatcaaaga aacgaggatg gagggctgac tgacgattga cacaaacaaa
    70861 ttcaacaatt tatccattga tagttcctcc cttgaatcat ttttattctt ttgacaagat
    70921 cttcgttact ttttctttta cttcttcgct gtcaatgatc gattgcaaag gtacgagctt
    70981 ttcatcaggt atagaagtta gcgtatcttt caaagaatgc tcaatgaaga aataatcagc
    71041 catatcgcta gatacacttc caacatccgt atgacttact tcaaactcgt ccacatctgc
    71101 tccaagatct gcaagtgctt gtttgatgtt catctctacc ataaaacttg ttcctaatcc
    71161 actttgacat actgcaaaaa ttttcatatc attcgtctcc ttttcttatg atcgctaata
    71221 tttcttcttt tgttgatgcg tgtaataaat cttgaagatt ttgtttatta gaaagtagct
    71281 ttgttaaatt tgccaaagcc cgaagatgtg cctcattatc gatagcagct aaacagatga
    71341 acaaactaat gggatgggct ggattatcaa gcagatccac aggttgttga agtttcagca
    71401 aagacatccc tacttcgttt acgccatctt ctggacgagc atgaggtaat gcgatgtgat
    71461 cgccaatatg gataaacgca ccatactgct ccacgcgctc gatcatagct ttgatataac
    71521 tttcttctat tttattttct gataatagcg gctgtgcggc aaatgtgatt gcttcttgcc
    71581 agttttttgg ttgatccgat aattggatca tttcttctgt taataattca gatagcatag
    71641 gacgttgatc ctccttcttt tctaaaagtt tgttcatttt acgatttaat acttgataga
    71701 gcttttcttc gtctacgcct tcttttaatt cgatataagg cagtagcgcc gacaacaatt
    71761 cttgggcaga aggcattgaa aatcctggta tcagccaatc tctttgtact tgattgatca
    71821 gctgattttt ttccaagtca gtcatgattg gatgcagaac atagagagac tttttcttat
    71881 cagtaagtgt gagaggtaca gtagaaaaaa taatatcgta agaagtttcg tcaacctcgt
    71941 gtaagcggtc agctgaatta gtctctgtaa aaaagatcat cgggaataat tgctgaagtt
    72001 cactttttaa gatcaatgaa gagctaatgc cacttggaca gacgatcacg gctcttattt
    72061 ttctatttct ttcttctgcg tccgcttttc tgatctctcc gccaaatagt atagtgaaaa
    72121 aaccaatctc ttcttcaggg atgctcttcc ctattcgtct ttctaacgga agtaatgctt
    72181 ttcttgtcat ttcgtagatg gaagcatatt gatgcttaat ttgatcgatc atcacattag
    72241 gtaaataaaa agaataggaa atacgaaaat aggcagggac caagtgataa aagacattca
    72301 tcaataattc acgaaacgaa gcaaattcta cggccatcag gaattccatg cgatggatga
    72361 cttctgaaga acattccagc aaaaaatcaa gtgcaggctc ctggacatct ccttcaacga
    72421 tcgatgctaa gcaaagagag aaaaatataa tctccgaatt ttgatgttcg gaatagccaa
    72481 ggccagtcaa tacttgtcga ctaatgtcag tgactgcaag agaagccaac agttcagcat
    72541 cttttaccag ttccatggat gtttttccaa ttcgaatggt tgtcaaactc aaataataag
    72601 ctaattcatc cattcgattt ggtgcgaatc gaagatctga tagtgaaatc gttttatcta
    72661 gcaaatctct aactttggcg taataatcaa tggaaagggt tgcggttaaa tacgtgagcc
    72721 caaatcttcc agcaagtgac tgcatcaaac gagcagtgcg attttttgct tctcttctta
    72781 atattgcttc tgaccctagc agcctaaaac cagttttcct agtatacgac agctgacaat
    72841 cttccacttc taattcattt cttatctttt tgatatctga caggactgtc cctttagaaa
    72901 cctgaagaaa atcttgaaaa tgaaaaacag aaacagacgt tgcagtcgaa taaaccatca
    72961 aataaagaag atctcttcgc tcttgttcgg tatacacagc ttcaaatcga gtaatatcca
    73021 aaaatttttc tgcccagtcg attgctcgga atttctttat acggatacgg gtatcatcca
    73081 catattcggc aaaaggagtt aattgtttga tcgcctcgct tgtatttact tcgatgatct
    73141 ctgctgcttt ttctagactg atttctcttg gtgttttcag gagataacta attttgtagt
    73201 tcacagcgct gttcacctcc tacttatatt ctagtatggt agcgctttta aatcgagggg
    73261 tgtttggtac aacttacagt tggatttttt ttacgactgt accgaacgat ttctatcgaa
    73321 tggatacaga aaaaaagcag gtgaccaaat gtctcctgct tttatgaatt gatttcgtcc
    73381 gatcaatgat gatcatgttt attttttgag gtcagttctt caaatttttc tttgacatct
    73441 tcaaccgctt tttcgatatc tttttcaaag tgattgggct cattaggctt tgtttcctct
    73501 tctacagaat ttgaaccaga taaagctgtt tctttatttt ctgtttcacc agagtttgtg
    73561 ccagctaatg attcttcttt gtcttctgtt tcaccagaat tagttcctgc taaagccact
    73621 tcttcttctg ttttaggggc cattgaacct cttaatcgtt tgtgtttttc accgtcataa
    73681 tttgtcatgt tggttcctcc tagtagttct atactttttc atcgtacaat aagacagttt
    73741 atgcgtcaaa aaacaaaccc gattcttaca aatatgtcat atttttcctt ctgattcttg
    73801 aatgcttttg attccttctt ccaaaatttt catttgtaag attgtttctt catctttgat
    73861 gactttttct gcgccattaa ctaatgtctc gtaaatccct tcgtagacac ggctgtaatc
    73921 accaacctcg gaaattactt tttcttcatg ataactccct tgttcatcta tataggtcaa
    73981 tacaccataa tgttcgggca aatcgatacc aaagtcttca tgatcaggca tgtaaaacat
    74041 tttcagatgt tcttcttgtc gatcttttgt ttgtttcacg aacatccctt tttttccgta
    74101 aacgacgaaa cttggacgtt ctttgatgcg gaaataactg gattttatcg aaattttcat
    74161 atttccatag aaaaaatcca gatcgaagta atcattcatt cgtcctttcc ctaaaagttg
    74221 acgtacatca tagctgatat catctggttc gccgaaataa gaaagaactt gatctactgt
    74281 atgacaagca tgtccatata aatagctgtt cgcagtagaa aattcatgcg tattttctgg
    74341 tacttccggt ctgaaataat cataatgcat ttctacttct aaaatatccc ctaattttcc
    74401 gctttcgatt actttttgga ctgtcaagaa gtcagaatcg aaccgtctgt tttggtaaca
    74461 ttggataaat agaccttttt cttttgctaa tgcaaataac tcttctgctt cctttgacgt
    74521 ttctgcaaaa ggtttctcta ctagtacatt cttaccatgt tcgagtgcca tttttccata
    74581 ttcataatga aattgactag gtgtagtgat gacaactaat tggatctcag gatcatccca
    74641 aagatcagac agctgatcag tatattcgat gtcttcgaat gttttccaca ctggttcaga
    74701 tggggaaaaa atttttttga tattgatttt gttcgtaagt tttcttgaaa aaggcaaatg
    74761 atagcgattt gtactctttc cattgccaag ataagcgatt gtaagcatga gtggtgcctc
    74821 cttttattga tgttttcagt atatcctaga aaagcgcaga aagtatttat aatagctatt
    74881 ctggtaaaaa agttcagaaa aacacttgtt atcattcggt ttggtgaaat taatgttcaa
    74941 agtaaggata aaaatcaaaa agatagtagc ggaaccaagt gtttatcagt aagatagaat
    75001 ttggaggtca gatcatgctt attgaagaaa aactaacaaa acaagagttg tttaccacga
    75061 cagagaaacg gattgtcgat tacatccgta ggaatatcga agctgcagtc tacatgacga
    75121 ttgaagaatt agcaaaagct acgtatactt cccattcagc tatcattcgt ttatgcaaaa
    75181 aaatgggatt cagcggattt aaagaattcc gtttcgagct ggggcgggaa gttcatcaat
    75241 tgattgctca gttcaatcaa acgattgatc ctaattttcc tttttcaagt gaagatagca
    75301 ctcagcaaat tgcaaagaaa atggcggatt tatcgatcca gtcaataaaa aaagcacaat
    75361 tgcagattga acatgaagat ttagatcaaa tcggtaaagt attgaacaag gcacagcgaa
    75421 tctttctttt tgcaaaaggt gattctcaaa tcacggcaag gaaattccag aataaaatgg
    75481 tcaagttgaa taagtttttg atcatggctg aagaatacag tgattcttct tggaatgcag
    75541 ccaatttgac tagcgaggat tgcgccattt ttattagcta cagcggtcgc atccatcatt
    75601 atgaacgaat aatgacctat ttgaagcatg tagaggcccc taccttgctg attaccggaa
    75661 atcagcattc agaaatggcc aaacaggctg atatgtgtct tgttatatcg caggaggaat
    75721 atgattttgc taaagtagcg actttctcct ctcaaattgc cttcgattac gtattaaata
    75781 cgttattctc agtgatatat tctcaaaatt ttgaagagaa tatccgcaac ttgaaaaaca
    75841 aacaagaatt gatgcaaaaa ggccttctta aagaatatcg gaaaacttaa gaaaagatcc
    75901 tcatttagta ataagaaaga tagtgtttga taggctctct ttgatatcat cataaaaaca
    75961 ggctgaagtt ttctttttca aacctcagcc tgtttgttta cggaacgatt cgaatagata
    76021 tattatagaa atgaggaata gctaacttct gtttcttatt ttgaacgatt gacgaaaaag
    76081 atatataaga aggaggaaaa tcagtataca tgcagctaac aatccataca ggaaaaatcg
    76141 tttgttctcg gatactttct gtacttcttt ttgaacttct tttgcatgat aaggaacccg
    76201 gtgccctctg acaagtaagc gatgactgtt gaccatataa ggtgtacaag ttaggagtgt
    76261 cacgaaatcc tgcccttttt cgattctcag atcttttgta tcagtcggtt ctaccgtctt
    76321 gatctgatcg acttgataag cgagtgtccg tccattgatt tcgatataga aagaatcacc
    76381 taaagtcagt ttcggtaagt ctgtgaacaa ctttgcttga ggcagtcctc gatggctgga
    76441 aataacggca tgtgtatttt ctccccccgt aggataagac gttccttcca ataatgaggc
    76501 acctttttct agcagcacag tattcgtttc atcaaaaatt ggcaaatgga cattgatctc
    76561 agggatcgtc aaaataccga tcgtatgttt ctcaaaatag gttctatcct ttttcgcagg
    76621 ttcttttttc ttagtaaagg gatctgcacc tggatttcca ccttcttttg ctaattgctg
    76681 gtttttcttt gtcatgtttt cttggatttt agccatgact tcttcatttt ctttgaccgc
    76741 ttgttgctga taatgagaga tgatctgctg atccagataa ttattcagcg cgtcgctaac
    76801 aaatggataa gctagtatcc ctattcctga gagaagcaag aaaagcatca gcagatctag
    76861 aagtttcctt ttctttggtt tcatttgtgt tctccttgtg atgactgttt gataataaaa
    76921 gaaaaaggag catttgcgta atccgctgct cctttttcca attcttgcaa aaagactaaa
    76981 tctgactgtg cttgcgtcta gcaaagtaca gtccagcaat cagtagaagg actactcctg
    77041 caccgatata cacatagatt cccttaccgc ctgttgaagg aagtgtacct ttgtgtttat
    77101 ttggtatttt ttcaggagaa atcaactgtc ctgctgttac ataagattgt tcatcgatag
    77161 taaatgctac acggtttgtt aatggaacat atttttctgg cgctttcgtt tcttccagat
    77221 agtacgtgcc atattttaga cctgtcacat cgattaaacc gttacttgtg gttgtaaaaa
    77281 ccgttgctga ttctttcgcc gatacccagc tgacggcttt tgtggatggg tcgatcgata
    77341 aatatttcgc tgtgtcacta tcttgatcac gaacgacgaa ttctgctcca gcaagtgttt
    77401 ggtctgatgt aacgtcacca tctactttaa caaatcgttt gcccccagta acgacatcga
    77461 ctgacggtgg tgtttgatca tttgtatgcc cgttatcgac atttgcttgg ttagaaaatc
    77521 ctttggttgg atctgctttt tcgttcaaat gcatatagta aacgaatttc aatgtaccgc
    77581 caggagttaa tgaaggaata taattcggat caactgaaac cgtgaatccg tctgtttgct
    77641 cagtgacaga ataatttact gggtcgattt ctttatttcc atcatataag gcataagcat
    77701 acgttcctga agaatcatta tcaaatgtta aagcagcgtc atgagtatcg ataagtttga
    77761 atgttgtgta cttgttttgc gttccttctt tatcagcgat acctaatggg atattgacag
    77821 aaatctcata ttgaattttt tcaccgattg cgacatcttt tccattcaat tgaggtgttg
    77881 ttttatcaac tttagacgta tcatttttga tggtcttttc tactggtgtt tggctatttg
    77941 ccaggatctc aaaaggcgtg attgtttgct tttcaatcat ttccgcatta tcaggagctt
    78001 ttacttcttc taaattatat tttccaactt ctaaatgatt aacgatcaac tggccttttt
    78061 caatagatgc ctcggcaaag tcattgttgc cgatgtcata agaatgacca gtaatgaaat
    78121 gtttggcttt ggtttgatca gttgtccaag tgtacaatcc atctgtgaca ctttggatgt
    78181 attttttgac gcttggtgtt ccttcttctt tagaaataat aaattctgct ccatttagtg
    78241 cttcgttttc ggcagtaccg atttttgtaa ctttcaacgt tccatcatta ccgactgtat
    78301 ttttagggta gagatggata gtatctagtt cttctgtccc gtatttataa gagccatctg
    78361 cttgtttgat catctcatat acagggaaag ctaaaaccat gtttgcggca gctgacactc
    78421 cgtcttttgg ttcttctttg atcgtgtaga ctgcatcttt cccattttgt tttttaggta
    78481 aagataaagt gacatttcca tcagcatctg tcgttcctga agcaactggt gtaccaggag
    78541 tcaaagactg gactgcttgt tttgctgcat ccacggacgc tcctttatct cgttgcgcat
    78601 aaaattcttg agtgacgtta taaactgaaa atgaaatatc ggctaatcct tggtattgat
    78661 cgaattcgct catttctttc ccgctgtttt ggattaaagg atcgggtaaa tcagtcattt
    78721 tctttttatg aaggatgact tgagctgctg tctcctctgc aaacactttt tttgcgccga
    78781 agctgtttgt gagtaatggt aaaataagga aaaggactcc taacataacg tttatttttt
    78841 tatgattttt cattttttca ctcctgttct ttttttgata aacaaccaga ttgcaaagct
    78901 tgcgaatacc ataccaacaa cgcctaaaag tgtatttttc gtttcgtttg tttttggaag
    78961 aaatggacgg ctattttctt ttttattgac tactttcaat atactgtccg cctctttatc
    79021 ctcagaaaga aaagttgaaa tggtaaacgg aatttctgtt tcacttaaaa tataaccaga
    79081 aggtgcttcg atctctttta atcgataact tcctgttttc aacccggaaa ttgaaaaagc
    79141 gccattttta tcggaaatca ggtgaagcgc atctgattcg ttctttgtcc acttgtatcc
    79201 gttggctgtt tgctggaggt aatttcctgc tttgttttta ataaggaata ctgcgccagc
    79261 taatcgttta tctggtttat ttgtctcgat tttgacaaat tgcttactcc ctgtatatac
    79321 agagactttc tttgtactga caccaaaacc aaaatccagt gttccgttgt tgttgatttc
    79381 cttgttcgcc tgtgctgtac tgcttagctg catctgataa gaaatggtca gtttttttcc
    79441 agcatatttt tccaacgaag ggatcgaaaa taaaacatca aatccgtgag gtttcttgtg
    79501 tatgacaaag ccttctgtca gcttttctcc attcgatgaa atcgttaaac tattaggtaa
    79561 aaacgttaat gcttcatccg cactatctga caattcgaac ttttgatagt caaggatatt
    79621 tacaggaatt gtcgtatgca aggaataagt gattttttca ccaatcgtaa aatcatttct
    79681 aggctcttct aataccttct caaaaggtgg atcagggtag tcgttttctt catttttagg
    79741 atacaaatgg atagttgaaa gtttttgatt gttttgtcca tgtacaggaa gaacaactac
    79801 catattctct gccttttctt tgacgacttc tggtactttg gattcaatga aaagatacgc
    79861 tttatctctt ttttcttgat ctttagcggc cagagaaaaa gaagcgatac catcttcgtt
    79921 gttaagagtt gtagttgttg cttctgcggt aaacataccg gaagacgcac cgttttttgc
    79981 gatctctgct tgtgcttctt ctaccgtttt gcccttttcc cgtagatggt aaaaagaatc
    80041 tgtgacatca taaacttgga atgtgacacc atttaatcct cgatacgttt gtaataaagc
    80101 tttttcttgt ccgtcatttg gatgattttt cggcagttgc ccgtttggga aaagcaattt
    80161 gtgtaaagta atctgaacca tttctgtttc tgtttctgtt gctacctgag taaaagctgg
    80221 tttaaatagt aacaagaaga gacacatact aagccaacca agttttttca tatttagctg
    80281 ccccctcttt cttttttcaa aaaaagatac caaatagaaa acgcacaacc aatcatccct
    80341 actagataga ttcctaaacg gccaattcct cccgtttcag gtaatggtac ttttgcctga
    80401 ttcgtgatgt ctaaagaaat ctggttgttt ttggctcctg gtgacagaac agattcatga
    80461 tcttgtccat ccacttgaat tgacccatct tcgtgtataa ctatagtaac tggctctttt
    80521 agaccttggt atccttctgg tgtaaaagtt tcggtcagcg tataagttcc aggttttaaa
    80581 ttttcgaata gaaaggtatc tgtttcttgt ccatcttttg gcgattctaa gtccatttct
    80641 ggtccctgca gtctgaattt tgctcctttt aatgtctgtc cgttgtcttc ttttttgtgt
    80701 accgttagat caaacgcttt tagtcgattt tgatgagtga gcgtccatac attatttgtc
    80761 atctcggtat tttttcccgt gtaaatgatt tttccatatt tatcgatttg gaattcataa
    80821 tttcccggcg aagtatcata tccggcagga ccagctgttt caacgactcg atatttacca
    80881 ggtgtgagtg aatcaaaact ggcaagacct ttttcattcg ttgtttggct gtcaattggc
    80941 tgataagtac catttgcttc ttttttctgt agggaaaatg ctgctccttt aagatttatc
    81001 tctttgtccg tcccttgcat cgcatactta cgtactgcta caggaacttc aacaaaagga
    81061 ttttcaatag tcaactggat cgtatcatcg gaagtagtga ctgtttttcc atcaatggtt
    81121 accgtaccat cagaagcgat cttgatttcc caagtagtct ttttgcttaa tccatgccct
    81181 tctggagctt ttgtttctgt cagcgtatag gtcatttctt tttgcaattt gacattttct
    81241 ggaagagaat aggttccgtc gccatgatct gttagtaaag tatcaataga atctcctgtt
    81301 aatttgaaaa cagcgccaat aagatccttt tcacctgtag aggaattttt cgttattttc
    81361 aagtttaacg gtgtgaattg tttagtattt ttccatgtca ttgcatctat ttgttgagaa
    81421 tcgtatcctg gtacaggtaa ttctttgatt gtttggtaac tgaatgcttg accttgatta
    81481 ttgtattgag gtagtgataa tatctcttga taactttctc cgctatttgc agataatttg
    81541 tcaatgtctg cacgttccca cgtatttgtt gtatctttag ctggtttaat gattcgaata
    81601 tatccgtttt tccaagctgc agcatttgtc gtatgttccc gttgaatctc aaaagtaact
    81661 tgatctggac gatcagctag attgttgtca aattcttccc ataacttttt gatgtgaaga
    81721 ctgactccgg gagctttagc agatggtata ccgaattcag ctaattcatt ggtatcaatg
    81781 tttggctgga aagttgtcct gccgttcatt tgataccaga aatttggatg gaagtcctca
    81841 ttttctgttt ggattctcac ttggtaatgg atttggattt cttggtcttt tcctaaatag
    81901 atctgattgc tcttgatggt atttccttct atggaaatag atggagtgac cgttgtagga
    81961 cttgtcccca cactcttgac tgaaagtgta ccaggctgat aaatgaatgg ttctgcgatt
    82021 ggatcattta tttgtccatt gcttacagtt gctgagatct gtacagcttt tttggctagg
    82081 tattcagaga tatctgttgc atgatcagct gattcatagt aaagatcgcc tttttcatct
    82141 gatgaaacca tttgtcgcat acgagactct acttctgctt ttgagagacc agctgccgga
    82201 tcgctttgaa gttggatgcc aagaccatgt atttcgattc ctcgttcttt gagtgccatc
    82261 gcttctccga tggttgcgat aaacgtactg tcgattcttc tggatagatt gttttggtca
    82321 ggtgcatcat agattcttga gattagagaa gtatttcccg gccgatcttg cgtattagaa
    82381 aactgagttc cgtaataatt gctgcttgat tgtgcgtgta cccgctgtac tttataggaa
    82441 aatgttggta caccatccgt cagcaaaacg atcacttttt tatgtccatt tggaacggat
    82501 agcatgcttc ctgcatctct tagtgctttt tgtgtaaaag taccaccatt tgtccgtgaa
    82561 ggtgtaatgg attttacttg atttttcact gaatcaaatg aacccatctg tactgcaccg
    82621 ttactgtagc tatatccttc gcttgagtag ccgacatatc ccatattgat tttgtctgtg
    82681 ataccgctat ctgctaaagt atcgacaaaa cgatcgacac caatctttac ttcaccgatc
    82741 cgattattgt cgttcatact tcctgaccag tctacgacca atacgagatc aagaggcgtg
    82801 atatcttttt gtacatttcc acgagcattc aaataaacat caaacaatcc gggtgtactt
    82861 gtttcctttg catactttcg tatcgcatag tctgcttgat taccggttcc tccatattcg
    82921 atatacgaat gggtccgatc attaggatct ccattccaag aatttatacc atcccattga
    82981 tttgttccgt ttttattgcc ttgatgatca agaacatttg tatttcctgt aggttgccaa
    83041 ctggctttag gataagtgcc ctgatcatct gttgtatatt ctgtaggaat cgtttgatta
    83101 gatggcacac tcacagctgg caaggataat gtaggcaatg taaatgggct gacagaattt
    83161 tcgttttctt ttgatgattc ttcttctatt tcgtctggct ttggtactga cacatctgta
    83221 tctttcttat tttctgtctc atcaataatg tcatattctt tattatcgac gatcagcttg
    83281 tttgcctggc tgtggtaaag tgctggatcg attggaaaac tcagatcgat agtttgttta
    83341 gtgtttgatg agatttccaa cgtaattttc ccgctattta cctgataagc atagccatct
    83401 ccttcttttc tttccacatc acttaagtaa ttttcgacta gaccaatttc tttttctatc
    83461 ttttcagcac tggtgttatt cgcatttagc ttgatgttca gtgctttttt tccagactga
    83521 tccgaaatga cttcagctga aattgtttct aaaactgttg gatcatctgt agtgtctgct
    83581 attgcagata atggcacaaa gtttgataaa ctcaatatta tcagcatgaa aataactttc
    83641 agtttcttcc ctgtggtcgt catttttccc ctcctttttc tttttttctg ttttgacgtg
    83701 aatagtgaaa attattaaaa taaacaggcg ttacataatt ttatttattt taatatgata
    83761 attattatac gaagggcgct aaagggaatc acaccaattt tcataccaat tggtttcatt
    83821 tatgaagttg attccttcga ttaatgagcg tttcattgaa agaaaagggt tgagggagaa
    83881 aaacatatga tcaggttgtt ggaacgaaac tatagaaaga tggaaaaaat cattcgaatt
    83941 ctgtccattt ctgacaagtg gatgactaaa aaagaacttg ccaaacgaat tggtagttca
    84001 gaatctacat ttgtaaggta taatcgaaga gatcaaaatc cgctggggaa cggatgtaac
    84061 gattcaatct tcacaaaaat tggggtatcg tcttgaacat ttgaatgtac cagcttattt
    84121 aaatgttctg atggaaatgt cgcaaagttc tacaaacagt cgtttattaa atgagattat
    84181 tgtcaatccg ggtaaaacga ttgagtatta ttgtgaaaaa atttccatca gccggtcttc
    84241 ttttacacgt aagttgaaac aatgcaatca aattttagaa agctatttat taaaagtgat
    84301 cgttgaccaa ggttttcagt taactagcct taaaagtgag ctccagttgc gtatctttgt
    84361 tacctttttc tttttaagtt actacggaag acgcacgttg ccatttccaa tcgaaaaaaa
    84421 gaagatcaaa gaaattatgg tcaagaataa ttgtcagatg aatttgtttc aggaagaaag
    84481 cccatatgag caatctttct ttattatgta ttttgttgtg catctcatga gagaatccca
    84541 aggaactcca tttgaatgga aagctggaga ctcttatgta cagttgataa atatcgataa
    84601 aaaagacttc ttaatcttga aaaatctctt aggaaaattg aagtacagca gctatataaa
    84661 agtagtgaac tattttgtca atacgatttt ttcagaattt tcggagaaag aaaaaaatga
    84721 aatcagtgag cagatacgaa aaaatatgtc ctactgttcg ttttcatccg ctgattgcaa
    84781 agaaaaaaac gaagaatatg ttgttcaatt attaacgcaa atttattttt tctcccgtat
    84841 tttcccatac gatacgactc atttgacgat ccgtgcaact tactttgcac agcagatgca
    84901 acaccgccag atacgtctat atgctggatt tcgtgcagaa cttcaatttt attccactct
    84961 actgaatcag aatctgattt attatttatc tagctatatc ttttggatgc ttatcggtaa
    85021 tcctgaaatt caccattata cttctgataa aaaaatactg attatcagcg acttaagtct
    85081 tcgacatagt caatatattg aagaatatat cagtgatatt cttgctgtgc ataaaattca
    85141 ctctgagaca actgctatta ctgaagatca gctgtcgaaa tacaatcttc tcgagtatga
    85201 tctgatcgtt acgaatcaac ccattttgaa tgcccatgtt cctcatatat tgattgatga
    85261 tagtgtgtca ttcgcaaatg aagaagaact catccgctta ttcgagttat gaataatcaa
    85321 aaaacagcta tgtataaacc accctgataa aaatttcagg acaaatacac atagctgttt
    85381 ctttttattg tattccttca gcaatccaac gagatttata gcgaaagtct tttaacaact
    85441 cttcttttgt ccaattattt gcaatgagat ccgtcaaagt gttcattacg agggtcatgg
    85501 aaaagtatag gaaactaact gcttcttccg acgattgaat ggagaaatga ttgattctta
    85561 ataattccag ccatttttcg ttcattggag aatcagccga tagttctcta cgtttggttg
    85621 tctgctgatc atttcgctgg gttaacaagt ataacctttg ccaatagata ctttcgtgat
    85681 ctaagtcgca gcaccactct aaatattttt cgatccccaa aaagaaatgt tgtttgtttt
    85741 cgctaatgaa ttttaagata tcttgatgga ctatgtgaga actgcttttg atcgtataca
    85801 aataagcatc ttccaaatct tgaaaatatt tataaaaagc accgcgcgac atccccatct
    85861 tgtcaacgat ttctgagact ttgacttggc tgatgtgctg tgagcaaaat atctccagta
    85921 ataggtcatc gattctctgt ttctttgcgt tcgataaatt gaaaaaagtt tcttttggca
    85981 tccacatctc tcctttatct ctgattatac gtggatagcc cttcattgtc atgaaggatt
    86041 cattccttct ttttctcttc ttctgtcaag tacccatctt ccattcgata aacgcgatca
    86101 ctccattgaa tcatacggac atcatgagta accataatag tcgctttttg tttctcatga
    86161 gcttctttaa ctagtaattt gacgacttca tatgcatgat ctgtatccaa actagctgtt
    86221 ggttcgtctg ctaagatcaa gcttggctca ttatataaag cgcgagcaat tgccactctc
    86281 tgtctttctc caccagaaag gtctttagga taactatttt taagtgactg gatatctaaa
    86341 gattgcagca aggaatcgat ttttgttgaa tcttcttttt ttgaagtaac ttggtcaact
    86401 agttcaaatt gttcctttac cgttaaaaaa ggaatcaaat tagagctttg gagaataaat
    86461 cctatttctt taaagcgtaa atctgctcgt tttttttctg gaagctcagt tagtgagtga
    86521 ccgttgatca ctatttctcc ggaagtcggt gtttgcaatc ctcctgaaat ggtaaggaaa
    86581 gtacttttac ctgaaccaga aggaccaatg atgctgacga attctccttc ctttacataa
    86641 aaatcaattg ctttcaaagc tgagaccttt gtatgaccag aaccaaatgt tttggtaact
    86701 tttttcatcg ttaatatttt tttcattttt attaacctcc tattgctgta attgggtcta
    86761 ctttggttat cgtacgtatc gaaaacaatc cgcctagcat tgcgacaatg atcaaaatcc
    86821 cactatatag caaccattgt gaccaaaaaa cagcaaaagg catcgcgctt ggtaaaatca
    86881 gactagtcaa ataagcaaac aaaagagcaa gcagaacgcc taccacccca acaataaagg
    86941 actgtgctac taaagattta gcgatgaaga aatttttgat cccttgtgct ttcattactc
    87001 caaaaatagc agtcttctga agtgtcatca cgtacatgaa aataccgacc acggcagcaa
    87061 ccactaagaa caaaaagtat atcatcgcat ttaaggtcat attttgggca gaatagccag
    87121 gaatactttc aatgaatgtc ccaatagtta ataactgtag acccttcgat gctttttctt
    87181 tcgaaatttt agctgaatcc tttattacga tcccattgat cggctgttct tcttcagaag
    87241 caaacggctg ttgtccatac ttcaaagcag tccacgtatc tagggacgca tagatgacgg
    87301 gagaaactgt gtaataagtt tcaggaaaga taccgacaat cgtcaaagga tcgtcgtaac
    87361 tgccaatttt gatcgtatct ccaattttat agcctgaatc agccagattt tgagagatga
    87421 tgatttcatt ctttgtttta aattcatgcc ctttcgtgag ttttggtaat aaaaatgctt
    87481 ctttcgttgt gccgaaaact gtaacatttt ctttgttttt tcctttgatt gctccgctgt
    87541 acaatccgat tggtgctttc tctcctcctt caatgtattt cagatctcct cttgttaatt
    87601 gtgaagctgc aaatacttga tttgcatcct ccgacaaaac aatctcttgt gcgtcccaat
    87661 catcgattgc ttttttaaac tcttctgaaa gtccattcgc tagtcctgac aacatgaata
    87721 cgacatacgc aatcaagaac ataataccga cgatcaagcc atatcgtaat ttagaatagc
    87781 gaatttcttt gatagctaga aacatttgtt tttcctccct atgatagatt gatagtgaca
    87841 aaatgtcact tgttgaatag tgtaactcta aagtgacaat ttgtcacttg tgttgttttt
    87901 ttcttatcaa taaattgtct aagacatctt tcgataaaac cttaacatga gtcataaaaa
    87961 atttatttaa gccttattta tgctttccat gataaactaa agtgaccaaa tcaatgaggt
    88021 gggaaaatga ttaaactatt agtagtagaa gacgataaag tattatccaa taatataaaa
    88081 gaaatactcg ctgcaatcgg cgagataaca caagtttatg atggtagtga aggactgttc
    88141 gagttggaaa gtggagttta tgatcttgca atcttggatt tgatgatgcc ggaaatgaat
    88201 ggatatgaag tgttagcaaa aatacggaaa gaaaaaatac agactccagt attgattttg
    88261 actgcaaaag atagtttgga agataagatt gaaggatttg aacgaggtgc agatgattat
    88321 ctaacaaaac ctttctatcg agaagaactg atcatgcgcg tgaaagcatt attgaaacgc
    88381 tcgctaggtc tctttgatga aaatgttctg aagtataagg atatcagttg tgatttaaaa
    88441 agcaatgaag tcttgtataa agaacaagtt ttgcccatac aaggaaaaga gtttgaattg
    88501 ctcgtttatt ttttacaaaa taagggaatc attttgacaa aagagcagat atttgaccgg
    88561 atctggggat ttgattctga tacgacgatt acagttattg aagtttatat gagcaactta
    88621 cgaaaacatc tgcgaagtac tggattggat aaagaaatca aaaccttacg taatgtcggt
    88681 tatatactgc aaagggtgtg atgcaatgaa tggagatatt acacgaaagc aacgtagtcg
    88741 cttttttgcg acaaatgtag cagcatttgc ttttatcttt tttcttttgg gattcattac
    88801 tttacagata ttaaaccaat ctgcatacag agaaacagat ctgtcattag agaaaataaa
    88861 ttttgattct cgaacagtac aattagagat acaaagatat cagcaaggcg atcccttttt
    88921 aaacccgact caaacggaac aaaacagaac aaacatggaa cagccattaa tggaaccatc
    88981 aaatgaccgt tttaacactc aagtgatctt gtggtctaaa aatggtgaga tattgaataa
    89041 agcagctatt ggtgggcgtt tcaaccaaat caaagaatta aaaatggata cgaaaaatct
    89101 gaataccatc caaaatattg aattaaatga agacagtggc tcatctgccc tctctttccg
    89161 ttcgattacg aaaaaagcgg agacgaatca agatggcgtt gcctacatcc aaattttaga
    89221 aaatacaaat caaatcaaga attcattagc gacttttcgc acgattatga ttttgtgtat
    89281 gattgttttt tggattctct ctattggtat cagttattac ttgtctagtc taagcatgcg
    89341 ccctattatt ctttcttgga gaagacaaaa agaatttgtt gagaatgctt ctcatgaatt
    89401 gcgcacaccg ttaacgatta ttcaaaatag tttggaacat ctttttacca agcctaatca
    89461 tactattatt gaagaatccg aaagcatcgc tcaagcattg tcagagacga ggcgcctcac
    89521 tggattgact tcggatttgc tgacaatcgc tcggaatgat tctgatcagc agctgctttc
    89581 aaagcaaatg atcaatacac aagaatatat cgaacaactt gttaaaccat ttcaagagat
    89641 ggccatcata gatggaaaag agtttattct ccataacgat gcaacattag aagtaccaat
    89701 tgatgaaaaa aaaatccatc aagttttggt tattttgctg gataatgcat taaaatatac
    89761 gaatccagaa gataagatca ttttggattc atctgttaac cataaagaat ggctgattca
    89821 cgtaaagaat actggccctt ctatcagtga agaagatcaa gcaaggattt ttgatcgatt
    89881 ttatcgggaa gatcaatctc gggcgaaaga gactggcgga tacgggcttg gcttggcaat
    89941 tgcaaaacag gtaatcgaac agcatcatgg acagatttct gtatccaatt atcttccaca
    90001 aggagtcgat tttaaagtcc aattgccgtt gaagcctaaa aaataatgct tatccctaaa
    90061 aaagggctgt gacaaaaatc ttgtcacagc ccttttttgt tgcgaataaa cggtgttcca
    90121 gaagtagctt cttcggaaat aagccgaaat ttctttaagc tgaccacttc tgtcacaacc
    90181 tctttagctt acgcttacga ttttttattg cggtcttcaa tgtgtacatc accgcttgtg
    90241 tcaatatcca attcttctcg gctaacatct tctgtcactt tttcaacatc ttcatgttct
    90301 tctttatgaa tcccaacttc ttcacgaata actgtatgtt tgcttacatc tacttgctct
    90361 tctttgattg ggatagtaat cgtgtcatct tccaattttt cgtctgttcc ctgtgaagat
    90421 tgatctgtta ctggtttgcg ttcgatgacg atttcttcac gtttgaccgg tacttctacc
    90481 gtttcagtat cgttgaccac atgtttgtgg atgtcgactt ctccagttgt cacatcatgt
    90541 gtatttacat ctaatttttc ttcttttagt tgaattgtat catcatctag atttggtttg
    90601 cgatcgatgt cttcagtctt gcttgtaccc attgtatcag tctcgccagg tacgtccatc
    90661 ggatcagttc ctggtgtcat attcaatgga tccgttgtat tttgaaagcc tgtcgtgcca
    90721 cctacgtcca ttggatctgt tccagtgcca gtttctaatc cagtccccat tgtgcttgct
    90781 gggctaacag tatcttgtgt atccattgta tcttctgttg tttctggctg acgatagcct
    90841 tttactgtga tgacaaattt tccatcagaa atatctcctc tatattgata taaaggatca
    90901 ttttctggtg tagccgtctc agaatcatag gtatcaaaag aaaaagtatc ttttattttt
    90961 tcccataaag aacggtcttc ttcaccatcc atccgatttt catctgtttc aacatctata
    91021 ccagacaatc cgtcaaatcc tagtctagat gctgcttcat cagtagtata aataacgata
    91081 tcatctcgtt catacccttc gttacgcaac cgttcaatta ctgataatgc ttcttccctc
    91141 gtactatagc ttccgatgac cgttaaattt ttctcttcca tgtaaattcc tcctagcaaa
    91201 tagatttatg attggtatat tgttacttat aaatttattc tataggagac gattgttttc
    91261 tacaaatatt tagattggaa tttgattaaa acaatttaat tgaaatttga aaacatttat
    91321 gttaatgaaa gtcatattct aataaaatgt catttgtttc tatatgaatt tttatgaaaa
    91381 atttcatata atttccactc gttgtgatgg tttaatttat ccaatccatc aataagcaaa
    91441 caacttatat aaaaaaggat taattctcaa tataattgct cctaccatag aataaatctt
    91501 catgtaaagt aatgaagtac caactatttc taatacttct ttaagaatta tcccaacaat
    91561 atcgttagac aaaccattat tgaataaatg gagagccaat cgattctgaa aaaatgtttt
    91621 ctaatttttc ggaaataaaa gaaagagcct cctgccatta gaacgaacca aatccatttc
    91681 attgctcatg aagtaaccac atagctaaaa agaggataaa tcaattaaaa gatcaaaaga
    91741 atgactgcac taataaaata actaaaaatg tatcttctta cttcatatct tttagctagt
    91801 acttagttaa aaatttgctt cctaagatca agacaaactg tctatcttca tttgatgaaa
    91861 tgcggtaaaa tatagaaaat gaacactatt ggagggaatt tgtaatggac agcaaaacta
    91921 gaaaacaact gcaagaaaag ttaaagcaac gtacacactt gctcccttcc gtctttcaac
    91981 agtttttaga agaaaatcgt tcttcccttt cattaggcag tcgctatgaa tacgcaaaag
    92041 attttcatct gtttactgat tatttgagaa aagtattttc tgaagaagtg gatgatcagc
    92101 tgattatcca tttagaaaaa caagattatc agaatttctt agctaaaatc tatcgacata
    92161 ctcgttcgtt ccaaactaca gcgaaccaag aaacggagca attgtttgaa aatagctatt
    92221 acgggatttc aaggaagcaa tattcattaa atcatttttt acgatttttg tatcaaaaag
    92281 gactgattga agaagagatt tctcttttgg gtacaagttt accggaaaca accaaagcag
    92341 ctccgcgata tatcgatgca gaacttttca aagattttga gcatttgttt atcccgattg
    92401 aaggctttca aacaagcaga gaagctagct ttgaagaaaa gaatagaccg aggaaccttg
    92461 caattactgc cattcttctg tattgcggat taaagatcca tgaagtagta gaacttaaac
    92521 gtaaagatgt atctttgacc aagcagattc ttaatctgaa tagaaaagaa aacagactga
    92581 ataaagtacc aataccaaaa gaagcgatgc catttctgga gaactatttt aagttaacag
    92641 cacaaaatac ggacgaaaat tcttttgttt ttcgttcctc acatgatcag caaatttctc
    92701 ctcggactat tcgccaaatt ttgagcaaaa ttacagtata taaaaacgta tcgccagaac
    92761 tatgcagaaa aacatatcgt tattatgcag aactatattt agatgatgct gacgcggtaa
    92821 attatttatg tggtaatcga tacctctcat cccattcttt tcaagatatc tgggaaaaga
    92881 tggttgattt ttcttatcac gaattagcgg cattcgttcg ggtttcttcc atataaaaca
    92941 aatgtatgat ctttttttca caataaacta tgttattata taaaggatta tgttacgatt
    93001 atcttgaatt tgtatattac ttaacaaaag ataatggagt gtgaatgatg gagaccataa
    93061 cgtattcccc tttgaactta tttacgaatt ttcaagaagc tgcagctaac ttttccgaga
    93121 ccccgattat ctttgatgag ccactttcag ctttcccaga attaggactt gaaacaactt
    93181 acaaaaaatg ctgcgaaagt gtgttgaaac gggcttatca attggctcat cttggagtga
    93241 aatccggaga caaagttatt atttataaga gttccgcttt tgacacatac cttctagctg
    93301 tttctgtgtc ttaccttggt gcagtgcctg tcatgacttc ttatcatcta ccaacaacaa
    93361 caatggaagt atttatcgat cgtttagaag accctttcat tttatttgat gatgagacaa
    93421 aaaagcgagt gagagaaatt tcaaatggaa caaaatcaaa acagattcc
//
LOCUS       DAFEIE010000004        86262 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFEIE010000004
VERSION     DAFEIE010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 86262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.004"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            10..588
                     /locus_tag="LP345_000334"
     CDS             10..588
                     /locus_tag="LP345_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759147.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(828..911)
                     /locus_tag="LP345_000335"
     tRNA            complement(828..911)
                     /locus_tag="LP345_000335"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(875..877),aa:Leu,seq:gag)
     gene            966..1145
                     /locus_tag="LP345_000336"
     CDS             966..1145
                     /locus_tag="LP345_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759148.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            1294..2511
                     /locus_tag="LP345_000337"
     CDS             1294..2511
                     /locus_tag="LP345_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1759149.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2695..3531
                     /locus_tag="LP345_000338"
     CDS             2695..3531
                     /locus_tag="LP345_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1759150.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3607..4755
                     /gene="nagA"
                     /locus_tag="LP345_000339"
     CDS             3607..4755
                     /gene="nagA"
                     /locus_tag="LP345_000339"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBL1759151.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            4976..6034
                     /locus_tag="LP345_000340"
     CDS             4976..6034
                     /locus_tag="LP345_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBL1759152.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            6038..7072
                     /locus_tag="LP345_000341"
     CDS             6038..7072
                     /locus_tag="LP345_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBL1759153.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(7174..7890)
                     /locus_tag="LP345_000342"
     CDS             complement(7174..7890)
                     /locus_tag="LP345_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL1759154.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7859..8644)
                     /locus_tag="LP345_000343"
     CDS             complement(7859..8644)
                     /locus_tag="LP345_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBL1759155.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8635..9384)
                     /locus_tag="LP345_000344"
     CDS             complement(8635..9384)
                     /locus_tag="LP345_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL1759156.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9682..10206
                     /locus_tag="LP345_000345"
     CDS             9682..10206
                     /locus_tag="LP345_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBL1759157.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10222..11721
                     /locus_tag="LP345_000346"
     CDS             10222..11721
                     /locus_tag="LP345_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBL1759158.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11809..12411)
                     /locus_tag="LP345_000347"
     CDS             complement(11809..12411)
                     /locus_tag="LP345_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1759159.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12515..13471
                     /locus_tag="LP345_000348"
     CDS             12515..13471
                     /locus_tag="LP345_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBL1759160.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13776..14732)
                     /locus_tag="LP345_000349"
     CDS             complement(13776..14732)
                     /locus_tag="LP345_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1759161.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14906..15466
                     /locus_tag="LP345_000350"
     CDS             14906..15466
                     /locus_tag="LP345_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759162.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15459..16283
                     /locus_tag="LP345_000351"
     CDS             15459..16283
                     /locus_tag="LP345_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBL1759163.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIARYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16293..16910
                     /locus_tag="LP345_000352"
     CDS             16293..16910
                     /locus_tag="LP345_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL1759164.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16928..17611
                     /locus_tag="LP345_000353"
     CDS             16928..17611
                     /locus_tag="LP345_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL1759165.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18294..19577
                     /locus_tag="LP345_000354"
     CDS             18294..19577
                     /locus_tag="LP345_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1759166.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19593..20480
                     /locus_tag="LP345_000355"
     CDS             19593..20480
                     /locus_tag="LP345_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1759167.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20497..21333
                     /locus_tag="LP345_000356"
     CDS             20497..21333
                     /locus_tag="LP345_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1759168.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21336..21959
                     /locus_tag="LP345_000357"
     CDS             21336..21959
                     /locus_tag="LP345_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759169.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21956..23248
                     /locus_tag="LP345_000358"
     CDS             21956..23248
                     /locus_tag="LP345_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1759170.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      23607..23704
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23820..24401
                     /locus_tag="LP345_000359"
     CDS             23820..24401
                     /locus_tag="LP345_000359"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBL1759171.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24404..25711
                     /locus_tag="LP345_000360"
     CDS             24404..25711
                     /locus_tag="LP345_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBL1759172.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26127..26615
                     /gene="purE"
                     /locus_tag="LP345_000361"
     CDS             26127..26615
                     /gene="purE"
                     /locus_tag="LP345_000361"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBL1759173.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26608..27732
                     /gene="purK"
                     /locus_tag="LP345_000362"
     CDS             26608..27732
                     /gene="purK"
                     /locus_tag="LP345_000362"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBL1759174.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDLIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27745..29040
                     /gene="purB"
                     /locus_tag="LP345_000363"
     CDS             27745..29040
                     /gene="purB"
                     /locus_tag="LP345_000363"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBL1759175.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29220..29597)
                     /locus_tag="LP345_000364"
     CDS             complement(29220..29597)
                     /locus_tag="LP345_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759176.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29853..30581
                     /locus_tag="LP345_000365"
     CDS             29853..30581
                     /locus_tag="LP345_000365"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBL1759177.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30581..30835
                     /gene="purS"
                     /locus_tag="LP345_000366"
     CDS             30581..30835
                     /gene="purS"
                     /locus_tag="LP345_000366"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBL1759178.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30837..31508
                     /gene="purQ"
                     /locus_tag="LP345_000367"
     CDS             30837..31508
                     /gene="purQ"
                     /locus_tag="LP345_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBL1759179.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31509..33731
                     /gene="purL"
                     /locus_tag="LP345_000368"
     CDS             31509..33731
                     /gene="purL"
                     /locus_tag="LP345_000368"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBL1759180.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33716..35155
                     /locus_tag="LP345_000369"
     CDS             33716..35155
                     /locus_tag="LP345_000369"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBL1759181.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35178..36230
                     /locus_tag="LP345_000370"
     CDS             35178..36230
                     /locus_tag="LP345_000370"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBL1759182.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36227..36805
                     /gene="purN"
                     /locus_tag="LP345_000371"
     CDS             36227..36805
                     /gene="purN"
                     /locus_tag="LP345_000371"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBL1759183.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36802..38337
                     /gene="purH"
                     /locus_tag="LP345_000372"
     CDS             36802..38337
                     /gene="purH"
                     /locus_tag="LP345_000372"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBL1759184.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38353..39627
                     /gene="purD"
                     /locus_tag="LP345_000373"
     CDS             38353..39627
                     /gene="purD"
                     /locus_tag="LP345_000373"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBL1759185.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39749..40663
                     /locus_tag="LP345_000374"
     CDS             39749..40663
                     /locus_tag="LP345_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1759186.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40796..42361)
                     /locus_tag="LP345_000375"
     CDS             complement(40796..42361)
                     /locus_tag="LP345_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL1759187.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42354..43805)
                     /locus_tag="LP345_000376"
     CDS             complement(42354..43805)
                     /locus_tag="LP345_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1759188.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43819..44835)
                     /locus_tag="LP345_000377"
     CDS             complement(43819..44835)
                     /locus_tag="LP345_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1759189.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45055..46143
                     /locus_tag="LP345_000378"
     CDS             45055..46143
                     /locus_tag="LP345_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBL1759190.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYCATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46197..47723
                     /locus_tag="LP345_000379"
     CDS             46197..47723
                     /locus_tag="LP345_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL1759191.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47725..48930
                     /locus_tag="LP345_000380"
     CDS             47725..48930
                     /locus_tag="LP345_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1759192.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49187..50164
                     /gene="guaC"
                     /locus_tag="LP345_000381"
     CDS             49187..50164
                     /gene="guaC"
                     /locus_tag="LP345_000381"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBL1759193.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50428..51852
                     /locus_tag="LP345_000382"
     CDS             50428..51852
                     /locus_tag="LP345_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL1759194.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            52313..53422
                     /gene="pdhA"
                     /locus_tag="LP345_000383"
     CDS             52313..53422
                     /gene="pdhA"
                     /locus_tag="LP345_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBL1759195.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53425..54402
                     /locus_tag="LP345_000384"
     CDS             53425..54402
                     /locus_tag="LP345_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBL1759196.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54427..56070
                     /locus_tag="LP345_000385"
     CDS             54427..56070
                     /locus_tag="LP345_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBL1759197.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56078..57484
                     /gene="lpdA"
                     /locus_tag="LP345_000386"
     CDS             56078..57484
                     /gene="lpdA"
                     /locus_tag="LP345_000386"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBL1759198.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEEFVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            57646..57921
                     /locus_tag="LP345_000387"
     CDS             57646..57921
                     /locus_tag="LP345_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBL1759199.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            57927..58694
                     /locus_tag="LP345_000388"
     CDS             57927..58694
                     /locus_tag="LP345_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBL1759200.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            58862..60691
                     /gene="typA"
                     /locus_tag="LP345_000389"
     CDS             58862..60691
                     /gene="typA"
                     /locus_tag="LP345_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBL1759201.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            60952..62724
                     /gene="recQ"
                     /locus_tag="LP345_000390"
     CDS             60952..62724
                     /gene="recQ"
                     /locus_tag="LP345_000390"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBL1759202.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGRNKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            62838..63140
                     /locus_tag="LP345_000391"
     CDS             62838..63140
                     /locus_tag="LP345_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBL1759203.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            63143..64306
                     /locus_tag="LP345_000392"
     CDS             63143..64306
                     /locus_tag="LP345_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1759204.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            64332..67760
                     /locus_tag="LP345_000393"
     CDS             64332..67760
                     /locus_tag="LP345_000393"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBL1759205.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            67781..68905
                     /locus_tag="LP345_000394"
     CDS             67781..68905
                     /locus_tag="LP345_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759206.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            68895..69332
                     /locus_tag="LP345_000395"
     CDS             68895..69332
                     /locus_tag="LP345_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL1759207.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            69316..69654
                     /locus_tag="LP345_000396"
     CDS             69316..69654
                     /locus_tag="LP345_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBL1759208.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            69773..70333
                     /gene="rsmD"
                     /locus_tag="LP345_000397"
     CDS             69773..70333
                     /gene="rsmD"
                     /locus_tag="LP345_000397"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBL1759209.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            70330..70821
                     /gene="coaD"
                     /locus_tag="LP345_000398"
     CDS             70330..70821
                     /gene="coaD"
                     /locus_tag="LP345_000398"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBL1759210.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            70811..71854
                     /locus_tag="LP345_000399"
     CDS             70811..71854
                     /locus_tag="LP345_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBL1759211.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            72013..72741
                     /locus_tag="LP345_000400"
     CDS             72013..72741
                     /locus_tag="LP345_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBL1759212.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            72857..73102
                     /locus_tag="LP345_000401"
     CDS             72857..73102
                     /locus_tag="LP345_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL1759213.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            73099..73317
                     /locus_tag="LP345_000402"
     CDS             73099..73317
                     /locus_tag="LP345_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBL1759214.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            73453..73992
                     /locus_tag="LP345_000403"
     CDS             73453..73992
                     /locus_tag="LP345_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBL1759215.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            73985..76258
                     /locus_tag="LP345_000404"
     CDS             73985..76258
                     /locus_tag="LP345_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBL1759216.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVGTMID"
     gene            76296..77342
                     /gene="holA"
                     /locus_tag="LP345_000405"
     CDS             76296..77342
                     /gene="holA"
                     /locus_tag="LP345_000405"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBL1759217.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(77431..77685)
                     /locus_tag="LP345_000406"
     CDS             complement(77431..77685)
                     /locus_tag="LP345_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBL1759218.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(78085..78354)
                     /locus_tag="LP345_000407"
     CDS             complement(78085..78354)
                     /locus_tag="LP345_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759219.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(78824..79279)
                     /locus_tag="LP345_000408"
     CDS             complement(78824..79279)
                     /locus_tag="LP345_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBL1759220.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(79417..81345)
                     /locus_tag="LP345_000409"
     CDS             complement(79417..81345)
                     /locus_tag="LP345_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL1759221.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(81542..82375)
                     /locus_tag="LP345_000410"
     CDS             complement(81542..82375)
                     /locus_tag="LP345_000410"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBL1759222.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(82567..83271)
                     /locus_tag="LP345_000411"
     CDS             complement(82567..83271)
                     /locus_tag="LP345_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1759223.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(83294..83920)
                     /locus_tag="LP345_000412"
     CDS             complement(83294..83920)
                     /locus_tag="LP345_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL1759224.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            84246..>86262
                     /locus_tag="LP345_000413"
     CDS             84246..>86262
                     /locus_tag="LP345_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1759225.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGID"
BASE COUNT        28003 a        14903 c        18552 g        24804 t
ORIGIN      
        1 tttttagaca tgaatatctt atttttattg ctatttttct taattttcct tctaacatat
       61 aggaaatgtc aaaactatta tgtgcgtata ttgactgcat taccgttttt cttaaacctg
      121 attatttatt ttggtaatac aatgggtcaa agctttactt acgtcaatgg aaataaaagg
      181 gcaatgattt ggagtagtag taacctgaat aatctcttta cagagttagg aacgaaactg
      241 tcactttttt atccaggtac ttggatagct actttagtag tcttggcatt attactatgt
      301 ttaattgttg gaatttattt aagttttgac aataagaaaa cttctatttt tttagttatt
      361 ttgatgataa tgggattttg ttcaaggtta attatgggat tttctcccac agtatgggct
      421 tccggaatgc ggacgtacta tatactttat gttgttatcg ccatcttagt actaatggca
      481 gttaaagagc taatgaaaag catgagtgta caaaaaaatg aatttatgca atttggatta
      541 accgtgcttg gtatttgtac ctttataata acggtgataa acagataata tacaaaaaat
      601 ccctcgcttt agtattaggt gagggatttt actcgttttt cgattaattg ttttaacact
      661 tgcaagtttc tacgagtagc ttgtttccga ccttcatata ctcacctcag gctgtttaca
      721 tgattgtacg ttctttttgt aaaggataca gtgatatgta tataatggca taaagaaacg
      781 ttcaaacaaa aaaactcgtg aagcaaaatt aacttcacga gttgtagtgc agatgatggg
      841 actcgaaccc acacgagcta acgctcacat gaccctcaat catgcttgtc tgccaattcc
      901 aacacatctg cgtaataata acacactaat gatagcgagg ttttacatag ttgtcaagct
      961 caaaaatggg aggacttatt aagatggaga aatatgacgg agaattttca ggactgggaa
     1021 tgatcttagg tgtattgatt ggacttgcat tcggacgttt tttgcttggt tttatgctag
     1081 gaatcatttg tggaatcgca atggattggg cagcgaatct atggaatgac tatcatgaca
     1141 attaagttct caacgcttgt ttgtgttttt ttaatactta cgtttttcct aaataagtgg
     1201 caaaattttc taggatggag tatgatattg aaatagtaaa taacaaaaaa tttggaaagt
     1261 tctaactttt tgaaatgagg gattggctaa gtgatgagag aatttgaaaa atccaacaaa
     1321 ttagaaggtg tcagttacga tgttcgcggt cccgttctag aagaagcgga gcggatgcaa
     1381 gaagagggca ttagtatttt aaaattgaac acgggaaatc ccgcaccttt tggatttgaa
     1441 gcaccaaacg aagtcattcg tgatttgatc atgaatgccc gtgactcaga aggctactca
     1501 gattccaagg ggatcttttc tgctagaaaa gcaattgagc aatattgcca actgaaacat
     1561 tttccgaatg tgacgatcaa tgatatctac accggcaacg gagtgagcga attgatcacg
     1621 atgtgtatgc aggggttgct ggacaatgga gatgaagtac tggttccaat gccggactat
     1681 ccgttgtgga cggcttctat tgcattagct ggaggcacac ctgttcatta tatttgcgat
     1741 gaagaggcag aatggtatcc tgatattgat gatatcaaat caaaaataac gagtcggaca
     1801 aaagctattg ttatcattaa tcctaataat cctactgggg cactttatcc aaaagaatta
     1861 ttagaagaaa tcgttgaagt agctcgacaa aataacctga ttatttattc cgacgaaatc
     1921 tatgatcgct tagtgatgga tggtctagaa catattccga ttgctacatt agcgcctgat
     1981 ttgttcgttg ttacgctgaa cggtctatcc aaatctcatc gtgtagcagg atttcgagta
     2041 ggctggatgg tcctaagtgg agataagtca cacgtcaaag gctatataga agggctgaat
     2101 atgttgtcct ccatgcgttt gtgttccaat gtattgtctc agcaaattat ccaaaccgcg
     2161 ctaggcggtt atcaaagtgt cgatgagctg ctcctgccag gcggaaggat ctatgaacaa
     2221 agagaatata tctataatgc aatcaatgat attcctggtc tttcagccgt aaaaccaaaa
     2281 gctgcttttt atatattccc aaaaattgat acaaagcgat tcaatatttt ggatgatgaa
     2341 aaattcgttt tggacttttt acatgaacat catattctac ttgtacatgg tggtggattt
     2401 aattggaacc agccagatca ttttcgaatc gtttatcttc ctaaaatgga tgatttgaaa
     2461 caaacagcta agaaaatgag agaattccta gcaacctatc gccaaaaatg attttaaaaa
     2521 ccaaattttt cagtaggagg gccacagaca aacacactga ggctctcttt ctagtggagt
     2581 tttcttaaat aactaaagta tattatttag ttgcaagtct tttcttgaag tttgcgactt
     2641 cctaaagtaa aatacgaata gaatgcgaat acgcatattt tggggaggat acttatggaa
     2701 acgttaatcg agtcctttgg aacgatcatt aaagagattc gaaaagaaca aaaaatgacg
     2761 caaaaaatgc tttcgcatga tatttgttca caaagtgtat taagtcggat cgaaaataat
     2821 gaggaactgc cgaatgtatt ggtgatgatg cagatttgtc aacggctagg ggtaacgatt
     2881 gatcatgtga tgaatctctc tcgaaaaact actcggacaa acgataaatt atttgaactg
     2941 ttggatagtt gtttccaaaa acgtgattat cggaagttag aacaagtact aaaatcttct
     3001 gatatttctg aaaatctgta tcaagcaact gactttcaac gctattatta ttatctcggt
     3061 gtttgcgaat tcacgttgcg tcaaaatatc tctcagtccc tttattattt gaaagaagca
     3121 ttaagctact ctagccaaaa agaaagaatc catgtttctg acacagaaat acaactgatt
     3181 agttgtatcg gaaaaatata tggtgtggca ggaaaaacgg ctgaagcacg ctactatttg
     3241 agtcgaagca tccaactgct gcatcaatca gctgatgaac gatcaaaaag tgaattttcg
     3301 caaatttttt ataattatgg aaatttctta ttccatcaaa atgaaatcga cgaagcgtta
     3361 gaacaggtga atcaaggaat ctattgggct caagagaaga atagctacta ttacctcaat
     3421 gatttatttg tgcttaaaag cttaatatac aagcgtaaag aagaaccaga aagagcagca
     3481 ttctatgaag gcttagcaca agctgtgaaa caaatttcaa aaaatttgta aatggtgtag
     3541 accattcttg acttcttctc taaataagag tactttagag gtagaaaaac aaagggagag
     3601 aatagaatga gaacttttat ctatgctgac aaattctttt tagcgtcagg tgtcaaacat
     3661 gcaggctatc ttgaaattac cgatggactt tttggtgaat acaccaaaga actacctgag
     3721 ggagaagtca acatcattga ccaaagcggc aaatggattg ctcctggttt ggtagataca
     3781 catattcacg gctatatgaa tcatgatgta atggataatg atgcagaagg catcaaagtg
     3841 atgtctgaag gtctgttatc ttgtggagtg acttcatttt taccaacaac attgacgtca
     3901 agcaaagaac gtttaaaaga tgtagctgag acaatcggca aaatgtatca ggaagcacca
     3961 ggagctaaaa tcaaaggaat ctattttgaa ggtcctttct tcacagaaga acacaaaggg
     4021 gcacaaaacc caagttattt cggggatcct gatttggata ctttccatga atggcaagaa
     4081 gcttcaggtg gtttaatcaa aaaaattgct ttagcaccgg aacgtcaagg tgtagaagag
     4141 tttgtcaaac aagtgactga agaaggagta gttgtttctc taggacacag taatgctaca
     4201 ctagaagaag cgcaaaaagc tgttgaagca ggcgcaagtg tatttgtcca tgctttcaat
     4261 ggtatgcgtg gattgaatca tcgcgaacca ggtatggtgg gtgcgttatt atctttagaa
     4321 catgtctttt ctgaattgat ttgtgatggc catcatgtac atccaaatgc tgcgggaatc
     4381 ctaatggaaa aagcaggaca tgatcatgtc gcattaatta cagactgtat gatggccggt
     4441 gggatgcctg atggaaatta caatttaggc gaatttccag tagtagtaaa agaaggaaca
     4501 gcacgtctag aatctggcaa cttagctgga agtatattga aattgaaaga agcaattaaa
     4561 aatgttgtag actggggatt agcaacacca gaacaagcag tcatgatggc tagtctgatt
     4621 ccagcaatca gctgtaaaat cgatgataca tgtggaaaaa tcgctcaagg acgcgatgca
     4681 gactttatcg tattgaaccc tgatatgaca ttggaagcaa cttatctaga tggcgtggaa
     4741 cgtttccacg cataatataa tttaagttaa ccttaaaact aaacttctta agtttggttt
     4801 taaggttttt tttgtgttct agtaaaaatc actttacata agtttcaaaa gtttctttaa
     4861 tttcctattg ttcaataagt aacaatgtaa agataaaatt aaaaatgtta atacgtatta
     4921 gcaaaataaa agcttttttt attgtgaata aatgaacata attaggagga gaaagatgaa
     4981 cttatttgac atttttcgat cgactttgac agatatgtcg attgtcagtg caatcacttc
     5041 aacagttttt attatattat tagggtttgt ttgtagaaaa aaggggattt tttctgaatc
     5101 tgttggaaaa attctatcga aagtcgtctt aacagtggct ttgccagcac tggcatttcg
     5161 agctttcatg caagatatca atacagaatt actgatgcaa ggaatcaatg tcttgatttg
     5221 gggattagtt atttatatta ttcttattct agtttcaaaa ccttttttct taagctataa
     5281 aggggataag caaacaacgt tgcgtgtcct gacgatcttt ggttctacga cctttttcgg
     5341 aacgcctatc gtcagtgcga tttatggtcc tgtcggcgtg atgtattcct caattttcaa
     5401 tattggctac cgaatctttt tgtattctta tggatacata aaaatgagtg gcttgaagat
     5461 ggaagctaaa aatatcaaag cgatgttcgt caatccaatc attatcgcta cttttgccgg
     5521 ccttttcatt tggctgttcc aagggtatct gccacaagtg tcagttacag gtgcagaagg
     5581 agagataagc caagtagcgt ttttgcgaat tgaccagact gcaccgtggc tatttcagcc
     5641 gatggattat ttagctggtt taagttcacc attggcgtgg ctagcaatcg gcgcaacatt
     5701 aggtgaagta agcttcaaaa aagctgcatc tgaaaaaact tcatggtatt acagtctagt
     5761 caaagtggta tttgtacctg cattgaatat cgtgattcta gcagttttga cggcaacgaa
     5821 tattctacca gtcaattttg aagcactggc aacaatcgtt atcatgatgg ctacaccagc
     5881 tgcaacagtg gcagcagcct atgctatcag ttttgatagg gaggcacttt tagcctccaa
     5941 tgcatcctta ctgtcaacta tttttgctgt ggtactgaca cctgtatgga tcgttgtatt
     6001 acaaatgatt catggcatag gtttattttc ataagaaatg gaggaagaaa gtatgagaat
     6061 cgcatgttac ggtgttcgtc cgaacgagat agattttttt gaaaaattga atatttacca
     6121 ttatgatctc agtctttatg aagaactgtt gacacatgac aatatcgtgt cagcaaagga
     6181 ccatgatgct gtattgttga ggggaaattg tatagcagat gagaccaatc ttgcaaaaat
     6241 gcaggaatat gggattcgtt atgtttttac acggactgtg ggagtcaatc atatcgatct
     6301 acaagcggca gctgattttg gtatgacagt agcccgtgta ccatcgtatt cgccaaatgc
     6361 gatagcagag ttatctttga cttttgccat gatgcttttg agaaatactg cgtatacgac
     6421 gatccgaaca tctttcaaag attttcgagt ggatgagcaa atgtttagtc gtgaaatcag
     6481 aaattgcaca gtagggatca taggaacagg caggataggg ttgacggaag ctgttttgtt
     6541 taagggacta ggagccaaag tgatcggcta cgatattcat cagacagaag ctgctaaaaa
     6601 agtattgacg ttccactcgc ttgaagagtt attagccaaa agcgatattg tcagtattca
     6661 tgtacctcat atcccaggtg aaaacgatca aatgatcaat gaaggatttt tagctcaaat
     6721 gaaaaaaggt agcatcttga ttaatacagc ccgtggagag cttcaagata atgaagctat
     6781 tttaagagct ttgaaaagca atcatttagc tggttttgca accgatgttt ttgcaaatga
     6841 aacagaggtt tttttccgat ccttcaagcc atgggagacg attccagacc ctgctatcca
     6901 gcaattagta gaaatgtacc ctagagttct tgtaaccccg catgtaggtt caaatacaga
     6961 tgaggcatta tcaaatatga tttcgacaag tttcgagaac tttcgtgaaa taatagaaac
     7021 tggaaaaacg aaaaatgagg tatctcttcc taaagcccgt caattaagat aagaaaacat
     7081 ggatattcgt caataaaatg tttaaaaata gtccaagtaa acagttgtta cttctgtata
     7141 cttggactat tttgtatggg ataattcgat gactcaacag taatctgtga gctttttccg
     7201 cccattcttt gtcaattcat aacaggttag cggccggccg atttccaaat atttgattct
     7261 ttcgttcaat atatcttgtt ctactaaaaa attcaaatat ttcttgacgg atatacgtga
     7321 cagtgagctt ttttgagcca gttcttttgt tgaaaaaata gtatcttctt ttagaataaa
     7381 tgcacttatt ttttttaaag tcagttttga cagaccttta ggcaaatcga tgaatgatgg
     7441 tatttcgtga atgggagtgg tgtggttgaa tacttgatcg atcaatttct gatcggcttt
     7501 ttcagtcgtt tggattgtct gagagaaagc aagatacttt tcgatcgcca gctgaaaacg
     7561 ttgcaaagtg aacggtttga tcaaataatc taaggcaccg tagcggatca cattctttat
     7621 ggtttcgata tcatctgcag cagtgatcaa aatcactggg atatcatttc cttgctgtct
     7681 aagccaagat aaaaaatgga taccactttc gccaggcatg tatacatcaa gcagcagcag
     7741 atctgcgttt ttttgtctga aatatttttt tccttcttct acatttctga aactttcgat
     7801 tacgttcata ttagggatgc tttccacaaa agtacgattc aattctgcaa ccattggatc
     7861 atcttcgatt atcaggacat ttgtcatcat tttgatcttc cttttttggt aattctagat
     7921 agacgattgt accgccattt gtttgtttgg aaaattctaa aaatccaccg tggcgtttga
     7981 cgattgaatg gatgagattc aatccaaacc cacgattgat tcccttcgtc gaaaaaccta
     8041 gcgtaaatat tttttctgag atttcttctg atatcccgac accgtcatcg cagacggtca
     8101 cgatgaatac ttcagcttct gtgtcatagt ttaaatgaat ccggacctgt ccgtttcttt
     8161 catgtttttg tagcacggct tcttttgcat tatcaagtaa gttccctaac acttgcaaaa
     8221 gtgaatggat ggagtcatcc atctccattt tagggataaa agaatcgctt tctaacagca
     8281 tttcaacaga ttgttctttg gcttcgttta ttttgcctaa taaaaaaccg gcaattgcag
     8341 gtactttgat cagacttgag acttggccaa tctctttttt ataattttga tttagctgct
     8401 ggataaaatg ggtgacttct tcatacttct tcaaatcaat caaaccagaa atgacatgaa
     8461 gtttattcat gaattcatgg gtttgagctc tcatggagtt tatatattgt ttcgtccccc
     8521 caagctcctc cattaatttc attacttctg atcgatttcg taaagttgcg actgctccta
     8581 aaaaacggtc attgctaaaa agaggtgtaa cgctagaaat agtttctatc ccatttaaat
     8641 acatggattg agtccgaacg gtcgtttgat gctcaatcgt ctctttaaac aaaacgtcat
     8701 atagattatc actgattttt ttcctacttc gaaatccaat agctgctctg tttggtagaa
     8761 aatgtttttt gcaggtgtat tgatcaagag gatagtttta tcagaagaga tggctaagat
     8821 tccttcatct acttcatttt cgataatcgt tttttcactt aactgttctg ctatttcttg
     8881 tggttcaagt ccaagcagta cttttttcat tttttgggca agaaaaacgg cgcctatgat
     8941 gcctacgcta agtccaataa tcaatgaaaa aacaatcatt ttttgtccat ctttgacttg
     9001 attgtcaatc gtgttgtttg ttaagccaac acaaactgca ccaataatct cttgatcata
     9061 ataaataggg acgaaatagc ggaagccgaa ccctaacatt ccttcttttt cagagaaaaa
     9121 ttcttgtcct ccaatcactt ttttcacatc ttcatgactt gagaaaggaa gaccgatgta
     9181 acttgggtct gcgtgagaat atcgaatgcc ttcagggtcc atgacaacga taaaatctaa
     9241 attcgatgca atcatgattt catttgttat tccttgaatc gcatgtgtcg ggtcaccagt
     9301 ctgcagcttt ttttggatga gtttatcatt ggcaacgatt ttagcaatgc tagagatttt
     9361 atctgacaca ctagatcggt tcatcgaaag aataaaattc ctgatcaata tggcagaaac
     9421 aatcaaagaa acgaatgtgg agaaacaaac gacaaggatg atcgtgttct ggagctttaa
     9481 tggttttttc ttaaaaaaag gaaacatagg ctacctcgaa agaatttatt gtgaaaattt
     9541 taacatgaaa acaaaaattt aacaaattgt caacgataaa cacaaccttc ctataaaaaa
     9601 caccactgag tcggtaaaag aagctataca gaattttcaa acattggtat gatagacgta
     9661 gaaatggaag gaggcgtgta tatgataggg ggaatcgcac ttgagacgat ttattggtat
     9721 acattgctga tttgtgcagg attggcagtc ctattgatta tttttggaga tgtattcgat
     9781 tttgatggcc cgcttgatcc gatgcttatt atcccttggt taactttcac aagcttattt
     9841 ggttttctag gtgagcgttt aacagatcaa tcatctttat ttttatttat tgctagtgga
     9901 ggcatatcga tagtgttggt atttttgctt aatttctata tattgatgcc gatgaaacat
     9961 gccgaatcaa cgatgtcgtc ttctgaaaaa actctggaag gacaagtagc tgttgtgatc
    10021 acaccgatcc ctgtacgagg tatgggagaa attcagttga aaagtgttac cggttccatt
    10081 agtcgtccag cttgttttta cagcccccaa gaacagacag ctgagcgggg aacgaaagta
    10141 ttgatcattg agatcaagga aagaatctgt tatgtcatgc cttatgaaag catgataaaa
    10201 gcttaaagga gcgtgtgtta aatggaaata ccagttgttt ttatcgcgat cgcaatcgca
    10261 gctttgattt tactgatgtt gctgatcgtc tttgtagcga agtaccagac agcaaaaccg
    10321 gatgaagcgt tgatcatcag tggaagttat ttaggaagca aaaatgtgca cattgatgaa
    10381 agcaataaca aaatcaaaat tgtgcgtgga ggtggcgcat tcgtcttgcc agtttttcaa
    10441 cgttcgaatc ggatcagtct attatcgagt aaattggacg tctccacccc tgaagtgtat
    10501 acggaacaag gcgtaccggt gatgtgtgat ggtacttcga tcatcaaaat cggttcatct
    10561 gtagaagaga ttgctacagc agcagaacag tttttaggca agacaagaga agaactggaa
    10621 aatgaagcaa gagaagtatt agaaggacac ttgcgctcga ttcttggttc tatgactgta
    10681 gaagaaatct atcaaaatcg cgataagttc agtcaaagcg tacaagaagt cgcttctgta
    10741 gaccttgcaa aaatggggtt gatcatcgtt tctttcacta tcaaagaggt cagagacaaa
    10801 aacggttatc ttgactcttt agggaaacca agaatcgccc aagtcaaaag agatgcagat
    10861 atagcagaag cggaagctct aaaagaaacg cgtatcaaaa aagctcaagc agaaaaagaa
    10921 tcacaagcag ctgaattaca gcgacaaaca gagatcgcag aatcattaaa agaaaaagaa
    10981 ctgaaattag caacctacaa acaagaacaa gatgttgcta aagcaaaagc agaccaagcc
    11041 tacaatttag aaagtgcccg agcacaacaa caagtaatcg aacaggaaat gcagattaaa
    11101 atcgtagaac gtcaaaaaca aatcgaactg gaagaaaaag aaatcacacg tcgtgaaaag
    11161 caatatgatt cggaagtgaa gaaaaaagca gatgccgatc ggtacgctaa agaacaagaa
    11221 gcacaagctc aaaaagtcaa agaagttact gaagccgaag cagaacgatt ccgtgtggaa
    11281 gcactggcag aagcggaagc caataagaca cgtttagctg gacaagcaga agccgaagca
    11341 gcactagcaa aaggaaaagc agaagccgaa gcaaaacaaa agatcgccaa tgccttcaag
    11401 gaatatggcg aagcagctgt cttgagtatg gttatcgata tgctaccgca attgatgcgc
    11461 gaagcagcac agccgctagg aaatatcgaa aaaatctctg ttgtcgatac aggaagcagt
    11521 tcaggagaaa ccagtggagc gaaccgagtg acaaattatg ccacaaattt gctttcttct
    11581 actcaagaaa cactaaaagc gacaacagga cttgacttga aggaaatcgt agagaatttg
    11641 tcgacacgtg ggactactag ccaagtaaat atgtatgaag cgccaaaaga ggcagaacaa
    11701 aactcgatga aggaagaata aagtagtaca cttcaccgtt caatcaaaaa tggaggaaga
    11761 ctttttaaag ttcttctctc cattttttta ttttattgca aaagaaaatt agtcctcgct
    11821 atttttcttt tgtttttgga tcttagcttc tatctcttgt aaatttgttc ttagcaatcg
    11881 ttctttcttt tggagttcga ccaaatcttc tgatagttct tccttctttt ctgtttcagg
    11941 aggacgaaga aagaaattga taccgattgc aatgaatgtc cctataaaag tatctagtac
    12001 acgttggata gcatacaaag cggattcgcc ttgagggatg ctcaacgcaa tcagcaacaa
    12061 cgtagctatt gcggaaatga taccggaatt attgttaata ccatctgaca cgacgatcac
    12121 aataataact agaataggaa gcaagatcaa ttctaccaaa aaatcattgt gaaaatagct
    12181 tttgacaaaa aaataaatga tagctaatgt accacctaat gtattgccga tgatcctaga
    12241 ctttccaaaa gaaacggttg tagtcaagtc ctgacgcaaa gaaaaaacag cagataatgc
    12301 agcaatcatc gggattcctc gttgagtcaa atgaaaaaac aagatacata aaaaaacagc
    12361 taaggcactt ttgatcgtac gcatacctag tcgaaaacgg ccaaattgca tagagattct
    12421 cctttttggt ctttttacta tcatacctaa acttttgtct gatagctagt ttttcattat
    12481 tcaagtataa ttaaaataaa aaagggggaa gtaaatgcgt ataggaatgc gaacagtcaa
    12541 aacagtgatc agtgtcttct tttcgatggt cacagcgggt agcttatcgc tgttgtattg
    12601 gccagctgca gggatcattg cattattaag tgtaggaaat accaagcgct ctacattgcg
    12661 tacgggcatg aatcgaatcg cagcctttat attagctacg gcaacagcac tgttcagttt
    12721 ttttgctgtt gggtatacta tttttggctt cagtcttttt ttattcctgt tcatcccgct
    12781 tgcctctcgc ttcaaattaa ccgaagggat agtagtaaat tcggttttgg tcactcatta
    12841 tttagtggag gaaaacatgt cttggcagct gatcggcaat gaagcgggat taatggcgat
    12901 tggattagta tttgctttgc ttgcaaatgt ttacatgcca gatcgtacga agcagctgaa
    12961 ggaaaaccaa atacagatcg aaaaagaatt tcgaaatatt ttgagacaaa tggcagaatt
    13021 tcttttatca gaaaataaag aagatgtgca gatcaaatgc gaacatttac tgacattcat
    13081 tcgcgaaagc caagaagatg ccagagaaca tcaagaaaac tactggctca gacagccgct
    13141 atactacgaa acttacttct ctatgagaag agcacaggcc aatgtgatta aagacatgct
    13201 ggaaaatcta gagagaatcc agcaaccagc ttattatgga aaacatatct atggtttatt
    13261 gatttatact gcagaaacat tttcagagtc aaatgatggc agacaaattt taacacgtat
    13321 tgaagaagtt tatgtattgt atcggcaaat gcctctgccg actagtcgcc ctgaattcga
    13381 ggatcgagca gaattgttcc agtttttgca gtcttttaaa agttttattg aaatcaaggc
    13441 agaattctcc caacaaaaaa tccaaaaata gaggttgtga attcagctaa tattcaggtc
    13501 aaaaagctga tttcacaacc tcttctttaa acggtgttct cctgtcaact cctcggtcac
    13561 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgctcct tgtgactcgg
    13621 agctgaacgg taggctcaca acctctttct taaacggtgt tcaaaagctt tcctctgcgg
    13681 taataagtcc agccaaacga aaaataggag gagctatttt tgtttggctg ttcttattac
    13741 ttgatgcaga acagcttttt cacaaccttt taaaattaca tatttttcca tagaacttgc
    13801 atttgatcca agatttcgat gacatctttt gtcaagaaga gagagcgatt gggcaagtca
    13861 ccttcaatca tgtgtaccat attctttatt tcgtaattca ttgcttcaga tgtattcccg
    13921 ctttcgatga attcctttgt accatctgta aataagatct ccgcacgatc agcacgcggg
    13981 taatcagcaa tcgtcacata accgttctca aaggcaacga taccgacttt tggcattttt
    14041 gcctgaaaag tcaagctgac agcagcaagt tcattttctt tgttacgcaa gatagtgacg
    14101 gattgttcgt ccacgcctgt ttcaaaagga accattgtag aggcaactac ttcaggttga
    14161 gagctcaaaa agaaacgagc gaaagataca gcatacgtac cgatatccaa cagagctcct
    14221 ccagctaatt ctggattgaa gaaccggttt ttagggtctg gttctttgta actgccgaaa
    14281 ggtgcttgga tcatttttaa agcccccagt tttcctgtat ccattattga gcgtaactgc
    14341 tgataaagtg gcatgttgaa gattgtcatc gcttctgcta agatcaaatt cttttcttct
    14401 gctaagcgca tagcgtcagc cagttctttt ttattcatcg tgatggcttt ttcacataga
    14461 acgtgtttgc ctgcttccaa tgctgccaag atatggtcga tatgctgtct atttggtaca
    14521 gcaatgtaca cgatgtcgat ttcagcatcg tctaacattt cttgatagct tccgtaagct
    14581 tttggaatat tgtaacggtg agcgaagttt tccgcttttt ctgaagttct ggaagcaact
    14641 gctgttagtt cgctcgtctc ttgattgaag ctttcggcaa actcatgtgc gatggtacca
    14701 agaccaacga ttccccattg atattttttc atctgaaaac gctccttcat agttggattg
    14761 agtttcttgt ctgtctatta ttataacaaa aatcacgaag aataaagagg agaggacttg
    14821 aaacattaaa aaaaatgaaa gcagcgattt aagaggtgct ttttgatcaa aacttaagta
    14881 gaatagttaa aaggagggga taaacgtgca tcaagtatat attgatctta ttatgagtgt
    14941 attattagaa cagtttgaaa ctgaaaaaaa ttttttagat gaatacttgc tgatcagtcc
    15001 agaacaatgg caaaaatgga aagatggcga gaaaaatctg ccatctgaag cgatgcagaa
    15061 agtaaaaaat cttttcactg attatgaatg gatgctaacg caaaagattt tgcgtcaaac
    15121 gattattttt cccgaaaaac gaaacgttgc cgttgcagag tacaagcaaa tcaaaacacg
    15181 catcgcgcaa aaatggctta gcagcaaagc agcaaaagtc gagctgatcc ctttgaaaaa
    15241 taatcagcag gctggtagat accttgactt gaaagtaagt attcaatatg atgaatgggg
    15301 ctatgatgat attttgaatt ttcgtctgcc agcagatgtt caaaaacaga tcgaaggaga
    15361 aaaaatcgaa cttctcgatt gggtgaatga aaatctggaa gaaacttacg ttcatgaggc
    15421 gaatggggaa cgtgaagaac aacgaaagga tttttcaagt gaataaattt ttaggatttg
    15481 gagcagttgt gattatgatc gcagcaatgg gctatgttat ttttagcgat gatgattcgc
    15541 atgttcaagc cggcaatcaa gcagtcgaac gaacaagcac caaaacaact gctagtaaag
    15601 aaaagaacag tcaaacaacc agcagcaagg taaaggacaa agaaacaaaa gatcgtacgt
    15661 ccaaacaatt gccagatgtt aaaacagacg attggaagct agttttggtt ggtccagatc
    15721 acaaattaga aaaagaaatt gatgagtcta ctcaattggc atcattaagt aacggatact
    15781 tgatcgacaa acgcattgct ccagaatatg aagcatttgc caaggctgct gaagcagctg
    15841 gatttccatt agtgatggtc tcagcttacc ggtctgtatc atcccaacaa caagttttcg
    15901 aacaaaatgt ccaagatgtg atgagtcgtc aaggtgtatc agaagaggag gcgacaaaga
    15961 ttactaaaga aacgattacg gagccaggat acagcgaaca ccacacaggt ctggcagtcg
    16021 atgtcgtcga tcaaaactgg tacaacagtt atccttctac tgtattggat gcaagttacg
    16081 gagatcagcc tggagctaaa tggatcgcag ataatgctgc gcagtatgga tttatcgctc
    16141 gttatccaaa aggacacgaa gatataacta agatcacata tgaaccttgg cacttacgtt
    16201 atgtcggtaa agaaaacgct gagtatatca ccaaacacca attgacgcta gaagaatatc
    16261 tgaatgaatt aaatgaaaag taggaattga tcatggcgaa aaaaaagtgg aaaaagcaaa
    16321 agcgcaagaa tatccgttgg ccagcagtgg ttgccggtgt agcagtgata ctcttagcct
    16381 ttgttttttc cttgaagaat ctgtcttctc cttttactga taatcagcaa gaaaatgaag
    16441 cgcaatccca tcagcaattt attgaacggc ttgttccgca tgcccaagaa ctacaagatg
    16501 gttatggagt gcttcctagt atcattttag gacaagctat attagaatca aattggggaa
    16561 aaagtacctt ggctagcaaa tacaataatc ttttcgggat caaggcttat ggggatcaga
    16621 agaaagtaag cctggaaaca aaggaatttg ttaacgaaga atggataact atccaaggag
    16681 acttcaaagt gtatgattca tgggaacagt ccatggatga ccatacacaa ctgttcgtcc
    16741 aaggagtaga ttggaatcct gcgctgtatg aaaaagtgat tacggccacc aactatcagg
    16801 aagccgcaca agcattgcaa gatgcaggtt atgcgacaga ccccggttat gcgcaaaaaa
    16861 tcatccaggt catcgagacg tatcaattga atcagtatga ccggagatag caaaggagaa
    16921 gtggctgatg gcagaacaat ttacgccaga aatcatgacg gaattgagaa aagatatcgt
    16981 aagagtaccg gaaatcattt tagaagcaag cgggatcaag atatttggaa aattgatccg
    17041 ttcgatcatc tttactacgg atattgcgat catacgtaat acaaatgcga atgcagtaat
    17101 tgctgtgtat ccttttacac ctcatccagc gattactaaa agcattattg aggcagctga
    17161 cattccagtt ttctccggtg taggtggtgg tttgacacaa ggtgctcgtt cttcctacat
    17221 gagcatgttc gcagaagcgc aaggttcgtt aggggtcgtt ttgaacggtc ctacgccttt
    17281 agagacagta aaagaagttt gtcgagtagt tgatattcca gttatcagta cggtaacgtc
    17341 gaaatataca gaaatagatg aaaagttagc agctggtatt tcgattatca atatcagtgc
    17401 aggtaaagaa actgcagaag cagtacgcca ttttcgtaaa aaatatcctg aacttcctat
    17461 cattgcgaca ggtggtccaa cggaagaaag tattgctgag accattcaag caggagcaaa
    17521 tgccatcaca tatacgccac caagtagcgg agagcttttt agtcgtaaaa tggaaaaata
    17581 tcgggaaact gagaaaaaga atcatgaata acaggtgaga atcaaaagac gaggaagagc
    17641 agatagtggc tcttcctcgt cttttgtact ccagtactat ttgttcagaa ttcaaaaaaa
    17701 agagaaattt ttttgttttt ttacctgtaa tgtacataag aagagttaaa accttttgtt
    17761 attattagca ttctaacaaa aaaatgtctt gatttattga agcgctttct atagaatgaa
    17821 aaacgaataa aaactaaaaa aggcacccga caatttagta gcagctaaat tgtcggggct
    17881 tgaaaagtca gcgggaactg accaatcaag ttgccatagt caatgcttgt gcatcgacgt
    17941 gtatattgta cctaatttca tacagaatta ctagttattt ttctgttttt tagggaagag
    18001 cgcacacgaa gaagcatgct tatttagcta tgtcaaggat attgggcagt tgtctgatat
    18061 ccttttttct ttgcgtaatt atcctcccat cattgaagca agaagtgttt ttagcgatga
    18121 aagaagaatc agcactatct aatttttctt gaaagtattg agttgttcat cctaggcaga
    18181 acgataaggc aagtcttggt ttttattccc cttgaaaaag atcgtttaat aaatatgttc
    18241 tgtataaaaa tacagtatat tgaaaaataa caatggaagt agaggtgcag agaatgaaga
    18301 aaagaatgag aatcatctta gctttaagtg ttatgttatt cttcttgacg gcttgtgggc
    18361 aagaagatga caaaaaaatc acgctgaaca tggcttggtg gggttcgcaa gtccgacacg
    18421 atgcaacagt aaaagtaatc gagctttatg aagaaaaaaa tccccatgtg acgatcgatt
    18481 atgaatttta tgattatgaa ggatattaca caaaattagg tacactagca gcatcagatg
    18541 atatctggga cattttccaa ctgaacaatc aatttcctca atacatcaat cagattgaac
    18601 cattagatga atatgtggag caagggataa ttgatatttc taatgcagat gaatcctatt
    18661 tagcaacgac gacttacgac gggcaattag ttggactgtc taacggggtg aattcgtttg
    18721 cgattgctta caataaaaat atatttgaac aattaaatat ccctgaacca gcttcaaatt
    18781 ggacatggga tgaatttgaa caaatcagct atcaaatcac tgaagaatta ggaatctatg
    18841 ctatttcaag attcgaagat tttatagctg gctgtattat tcaaatacca caagttgaga
    18901 aaggattgaa tttttataat cgggaagatc tatctaacag cttgggattt gaaaatccag
    18961 actatctaac agattttttc cagctgcgta aaaatctggt agacaaaggg gcccatccag
    19021 aaccaggtgg tggagctgca agtacgacgg atctgtcttt tcaggcggtt agggatagag
    19081 aagcggcaat ggtgtttcta tcaagtaacc agttgacaga aatattgtca ggggctcctg
    19141 aagatatgga gattcagttg attaatccac ctcgcagaaa agcagatgga gaatctggta
    19201 tccctttacg ttcttcgcaa atgctgagta tggcaaaaag ctcagcccat aaagaagaag
    19261 ctgctaagtt tattgatttc tttcaaaaca gtgaagaagc caatgaaatt ttaaaaggag
    19321 aacgtggtgt accaatcatg tcgaatattc gagaacagct cgctcgtgca gatgatgcaa
    19381 ctttgcaagc gacatttgat tatttagaaa tgatttccga tatggacaac ggcgaagtga
    19441 atgtctttga tagtgctttg aatccggaaa ttcaagacca atacaatctt ttagttgaaa
    19501 aagtcattta tgaagaagta acagcagaag aagcagcaga gagtctttat gagtttgcgt
    19561 caaacattct aggatagcag caggaggaag gcatgaaaaa agaaaaacta aaacggttct
    19621 tggatcaaga caatgtggtc ggttacgtat ttgcttctcc attcatccta ggatttctat
    19681 tgataacagt gataccgatg atcttgtcac tttattattc gttcaccgat tatcgtttgg
    19741 gaaatccagt ctcatggatc ggcttggata attatataaa gatgctgagt gatgcccgtt
    19801 ttttgaactc catccgagtc acttttctct atgtatttgc atctgtacct gtgaaactga
    19861 tctttggtct attgattgct tatcttttaa cgaggaatat caaaggaacg actttctttc
    19921 gttctttgta ttatgtgcct agtttgatcg gtggcagtat ttctatcgct ctagtttggc
    19981 gggagttgtt ttctaaaaac gggttagtga atattttcct ggaacgatta ggcgcacctg
    20041 cgctttcctg gtttagcgat caaaaactgg tcatgatccc tcttgttttg atgtctgctt
    20101 ggcaattcgg ttcggcaatg atcatctttg ctgcaggtat caaagagatc ccaggctcgt
    20161 attatgaagc ggcagagatc gatggagcga acaaatggca gacgttttac aagatcacgt
    20221 tacctcttct ttcgccgatc attttgtata acttggttat gcagacaatc gcggcgttta
    20281 tgacttttac gcaggcattt atcattaccc aaggtggtcc gaatgatgcc acgaactttt
    20341 atgctcttta tgtgtataac caagcttttt cttttaattc tatggggtat gctagtgcta
    20401 tttcgtggat catgctgttg attatgggag ctgtcacctt tctgattttc aaatcatcaa
    20461 aaaaatgggt cgttgtgtga atgagaggag gaagaaatga ataatacagt aacgaaatgg
    20521 tttcaatacg gttttatttt gctattaggt ctagtcatga tttatccggt cttatggatg
    20581 atcgcaggtt cttttaaaac ggatcaagag attatgagtg gttcgctgaa tttgattcca
    20641 gagacttttc aatgggaaaa ttacgcaaaa ggatgggcgg ggtttgctgg aatttcattt
    20701 tttactttct ttaggaattc gtttgtcatc tctgcagttt cgacgatagg gacagttctg
    20761 agctcgactt gtattgctta cgcattatcg agaatcgatt tcaaaggaaa aagattctgg
    20821 ttcgtcgtca tgttagtaac gatgatgatt cctgcacaag tgattttgat tccgcagttt
    20881 attatttaca atcggctgaa tttggttggg acgtatgtgc cgctgatttt accacatttt
    20941 tttggacaag catttttcat ttaccagatc atgcaattca tggtcagcat ccccaaagag
    21001 ttagatgaat cagcgattat tgacggatgc agcaagtata gtgtctttac caaaattatt
    21061 tttcctttgc tgaaaccttc gatcatcacg acgatcatca tccagtttta ttggaaatgg
    21121 gacgacttca tgggaccatt gatttattta aacaagccga gatcttacac ggtatcgatt
    21181 gccatcaaat tatttgcaga cgctggatct agtacgactt acgcgagtat gtttgcgatg
    21241 tctacgttgt cgctgctacc ggtttttctg attttcttat tcttcaataa atatcttgtc
    21301 caggggatca gtacaagcgg tctgaagggc tgaatatgaa aaagccaata gaagagatgt
    21361 ttctttacaa gctcaactac tatgtctgtc ggattttttt aaccagtctt atcagtaatg
    21421 ctcttttcgc tttagttcta ggatgtttgt tcactttagg attagtgctg tctgctcgtg
    21481 ttgtctatct gatttatttt ttgatgatgt atccttctta ttatctatct gtccattact
    21541 tggcagaaaa aaaggtatgt tggaggaaag gaaaaatcaa acggatgtgt ttcatcatta
    21601 cgttgtttca gctgtttgtc attatttttg cagttgattg gtatttatta gtgggaaaga
    21661 ttggagcttg gtatctgatt ccttttctat tgtgtctgtt gctttttgta tcccatagtt
    21721 tttttagtac gctaattgat atctgcaaag aagataaagc agatagtctt gtttatttga
    21781 tcaaaaggaa tatctggctg ttgtcaaaaa acgtcaaggg gtttctgtgg tatttatgcc
    21841 ttttgtatgg actgttctgg tgtatacagc atgatttttt actcactgca ttactgtatc
    21901 cagggctgcc atttgtcaca gtattttgct taaaagaaaa ggagaatgac tttaaatgaa
    21961 gaaaaaatat gtacaagtcg gacttggtgg gagagcgcgt tttttttatg aggcaattgc
    22021 ctctacgtat catcaaactt gtgaactagt cggtttttgt gatgtatctc aaacaaggat
    22081 ggattatgca aatcggatac ttgtgaacaa gtatggacag aaaaaagtaa agacatgtat
    22141 gccatcacaa tttgagcaac tactggatga cgtacggccg gctgaagtca ttattacgtc
    22201 agtagatcga acgcatcatg attatatcat tcgtgcaatg aaaaaaggat atgatgttat
    22261 ttgcgaaaaa cctctgacta tcgatgagga aaaagctcaa gaaataataa cggtccaaaa
    22321 acagacggga agaagcctgc gagtcacttt taattatcgt tatgcaccgt atcacacgaa
    22381 gataaaggaa ctgatagaaa gtgatgtgat tggtgatgtg ttttctatcc acttcgaatg
    22441 gctgttaaat acgcaacacg gggcagatta tttcagaaga tggcatcgaa ataagcacaa
    22501 tagcggcggg cttcttgttc ataaatctac ccatcatttt gatctagtga atttttggtt
    22561 gaacagccgt ccccaaaagg tatttgcatt cggtggatta aacttttatg ggatgcataa
    22621 tgcggagaaa cgcggagtag aaatatttta cagtcgatgc tatggaagcg aactagctaa
    22681 agctgatcca tttgctatag acctgtcagc caatgaggaa ttgcgagaaa tgtatttaga
    22741 agcagaaaaa gacagtggat atattcgtga ccgtagtgta ttttccgatg atatctctat
    22801 tgaagataca ctaggcgtaa cggtcaaata tgaaactggt gcgattttga cgtattcgct
    22861 aaacgcgtat atgccgtggg aaggattcaa tgtttctttc aatggcagca aaggacggat
    22921 cgaaatgaaa gtgatcgaaa agtcttacat caatgcaggt ggagataaaa aggatgaagg
    22981 agcagccgtt cttcagtcca tccatgtcta tccgatgttc ggtgagccat atgaggtaat
    23041 cgtcgaacaa gaagcgggcg gacatggcgg aggagatccg cgtttattag atgatctatt
    23101 tggtgaagaa aaagaagaag atccgtggaa tcgggcagca actcacgtag atggtatttt
    23161 gtcgattttg acaggaatcg cagcaaatca ttctattgct tcaggaaaag cagtagtgat
    23221 tgacgagctt gtcagcttaa aagaataaga atagatttac ggaaattact tcccgtagtt
    23281 tataaaatct tgccttattg ccgataggct gtcttttgaa cactatttat tcggaaaaag
    23341 gggctatgac atgctttttg tcatgccttc tttttatgtg ggctgctttt ttagatagga
    23401 gaaaataaaa ataactattt aaacccgaac aaaaaggaat aatgcattaa aaatcattag
    23461 attttacaaa aaaataagta aaccacgttg tcagtttcag aaagtagtgt tagactgttt
    23521 tcaatatttg aaacaacatt ttttattcaa atatggcaaa ctgccttcac gtgcaaaaca
    23581 gttgcaagaa aatgaattta cactattatt agttttacat acctacttat atatcgtcat
    23641 aatatggatg acagtttcta gccagtaccg taaatgctgg actataagta aaagattggc
    23701 tatttcaccc ttcttttctt atgataaagt ggagggtgtt tttctttaac agaaacatag
    23761 taggtttttg cacaaaagcg gttatttcgg tattaataaa tgataaagga gcaaataaag
    23821 tgaaagaatt agttgaacgt attcaaaaag acggacgtat attaggcgag ggcgtattaa
    23881 aagtcgacag cttcgtcact caccaagtag accctgtatt gatggaacaa atgggaaaac
    23941 ggtttgcaga agtatttaaa gaacaaggaa tcacgaaagt tgtgaccatt gaagcttctg
    24001 ggatcgcacc agctttattt gctgcaagag aattagatgt tccaatgatc ttcgctagaa
    24061 aagcaaaaag tttgacgatg gatgaagaat tattgacagc ttctgtttat tcttttacga
    24121 aacaagtgac aagtacgatt tctatttctc gtaaattttt atcttcagaa gacaaagtat
    24181 tgattatcga cgatttcttg gcaaacggac aagcggcaaa aggattgatc gaattatgcc
    24241 agcaagctgg agcgcaagta gaaggaatcg ggatcgtcat cgaaaagtct ttccaagatg
    24301 gacgtcagtt acttgaagaa atgggattga gagtcgtttc tcttgcgcgt attgcttcct
    24361 tgacgaatgg acaagttgag tttcttgagg aggacgcata atcgtggaaa aagaaacaca
    24421 aaatggaaaa gctgcggttt tagggctgca gcatctgcta gcgatgtatg caggagcagt
    24481 agcggtgcct cttttgatcg gtacaggact aggctttaat caagaacaga tgacttattt
    24541 gatttcaatt gatatcttta tgtgtggatt agcgacatta ttgcaattga cagttaaccg
    24601 atttttcgga attggcttgc ctgtcgtttt aggatgtgcg atccaagcag tagctccact
    24661 gatcttgatc ggaaccaatg aaggagtagg agctatctac ggatctatta tcgcttctgg
    24721 gatctttgtt gtgttagttt ctggtgtctt ttctaaaatt aaaaaactat tccctcctat
    24781 agtaacagga acggttatca ccgttattgg tttgactttg attcctgtag caatcgagaa
    24841 aatgggtgga ggtaatgcaa cagcagctga ttttggtgac aaaacaaatc tgctacttgc
    24901 atttgtgacg attctcctaa ttgtaggcgt gcaaatgctg gcaaaagggt tcattcgttc
    24961 aatcgcggta ttgattggtt tagtcggagg aagcatctta gctgctttca tgggaatgat
    25021 tgatctgagc gcgattggag atgcgccgtt gttccatgtt ccacaaccct tttattttgg
    25081 taaaccaact ttcgacgtat ggtcgatttt actaatgatc atcatttcca tggtcagcat
    25141 ggtagaatca acaggtgtat attttgcact tggtgacatt actgggaaaa atgttggaga
    25201 agaagaattg aaaaagggat atcgtgcaga aggacttgcc gttatcttag gcggtatttt
    25261 caatacattc ccttatactg gcttttctca aaatgtcgga ttggttcaac tttcgggaat
    25321 caaaacaaga aaacccatct atttctctgc attcttcttg attgttttag gattattccc
    25381 taaaatcggt gcgttagcac aaatcatccc tgagccggta cttggtggag gaatgttagt
    25441 catgttcggg atggtggcag tccaaggaat ccgtatgctg ttggaagttg atttcagcaa
    25501 tgataaaaat ctattgattg ttgctgtttc tgttggattt gggctgggtt tcaatgttac
    25561 gccgacatta ttcagtcaaa tgccgcaaac attgcaaatg ttcactggaa atggcatcgt
    25621 aatgagtagc attacggcta tcatattgaa tttgatcttt aatggattga aaaaagatga
    25681 agaaatattg gaagaagcct tcaagaagta atagagcaaa agaaaggttg tgaaatcagc
    25741 gttttgacct gattgttaga gaaacaaacg gaaaaatagt tcctcgtatt ttgccgtttg
    25801 tttgagctaa taccgagggt cagctgattg aacaccgttg aaggaagagg tcgtgagcct
    25861 gccgttcatc tccgagtcac aaggaacaat ttcaaaaaaa agcttctcat gtttgttgaa
    25921 tattgttcct tgtgaccgag gagttggcag gagaacaccg tttatccata aaaaggaatg
    25981 tgacctaact tttgtcacat tccttttttt tatctttaat aaacacgaac aataaaatgt
    26041 ttttctttgt taacattcga aatttctttg acatcaaaaa aagtgattgt taaaatatga
    26101 atgtagaaaa actgggagga aaaacaatga cagcaaaaat ctctgtgatt atggggagta
    26161 cttcagattg ggaaacaatg aaagaagcat gtcaaatatt ggatgaattc ggtgtgtctt
    26221 atgaaaaaaa ggtcgtttct gctcatcgaa ccccagattt gatgtttgaa tatgcacaaa
    26281 acgctcgaaa aaaaggaatc aaaatcatta ttgcaggagc agggggagcc gcgcatctgc
    26341 cgggtatggt cgcatcaaaa acaactttgc cggttatcgg tgtaccggtc caatcacgaa
    26401 cattaaatgg tttggattcg cttctttcga ttgtccaaat gcctggagga gtacctgtag
    26461 ctactacagc aatcggaaaa gcgggagcaa ttaatgctgg actacttgcg atacagatgc
    26521 tttccatgta tgatttagaa ttggaggcta aattggctga aagacgttca atgttggcta
    26581 aaactgttat agaaagtagt gatcaacttg gttaaacctt tgttgcctgg ttcaacgatc
    26641 gggatcgtcg gtggcggtca attaggtcgt atgatggcga ttagtgcaaa agaaatgggc
    26701 tttaaagtag gtgtgctgga tcctgtgagc gattgtccag ccgcacaagt tgcagattgg
    26761 cacattgaaa gtgtctatga tgacaccttt gcgctgaaag agcttgccag aagaacagat
    26821 gtcattacct atgaattcga aaacgtcagt gtagaggcgt taaatgcgat tttacccatg
    26881 tcatttattc ctcaagggac agacttgctt gcgattacgc aagaccgcct gttagaaaaa
    26941 tcttttttgg aaacgaataa catcgtgatt gctccttatg caacgatcgt cagtccgacg
    27001 gatatccaag atgcgattga cgggatcggc tatccttgtg ttttgaaaac cactcgaggc
    27061 ggctatgatg gcaaggggca gtatgttttg aaaagtcggg cggatctagc tcctgccatg
    27121 gaccttttaa gagaaggaac ctgtgtttta gaagcatgga tcccgtttga aaaagagatt
    27181 tcgatcatgg tggcaggaaa tggtcaagga gatttcacga cttttccggt cgtggaaaac
    27241 atccaccaca acaatattct tcatgaaacg attgctccag ccgcgattga tcaggatttg
    27301 atcgaggagg ctgagcgtat tgcccgtgtg attgcagaag cagtgagcct ttcaggtgtt
    27361 ttaggggtag aaatgttttt aacaaaaaca ggcgggctat atgtgaatga attagctcct
    27421 cgtcctcaca attctggaca ttattctatt gaagcttgtt ctatgagtca gttcgatgcc
    27481 catattcgag gtatttgtgg ttggccatta ggagaaaaag tacgtttgat aagcaatgca
    27541 gtaatggtca atgttttggg agaacaactg ctggaaagct atcgcttgat tgagaataag
    27601 ccagactggc aattccattt ctatggaaaa aaacaagcaa aaaaaggtcg caagatggga
    27661 catatcacta tcttgacaga agacatccag caaacgctgg aagaaatcaa acaaacgaat
    27721 atttgggatt agaggagaaa aaacatgtta gaacgttata cacgccctga aatggggaat
    27781 atctggacgg aagagaacaa ataccgtgcg tggctcgaag tcgagatttt agcagatgaa
    27841 gcttgggcag aacttggtga aatcccgcaa gaagatgtga aaaaaattcg tgagcatgca
    27901 tcatttgata tcgatcggat cttggaaatc gaaaaattaa cacgccatga tgtcgttgcg
    27961 tttacacgag cggtttctga aacattggga gaagaaagaa aatgggtcca ttatggtcta
    28021 acaagtacgg atgtcgtaga tactgcttat ggctatctca tcaagcaagc aaatgatatt
    28081 ttacgggaag acttgaaacg ttttacggaa atcattggcg aaaaagcaaa agaacacaaa
    28141 tatacagtga tgatgggtcg gacacacggt gtccatgctg aaccaactac ttttggattg
    28201 aaacttgcca catggtattc agaaatgaaa cggaacatcg aacgatttga acatgcggca
    28261 aaaggagtag aagcaggaaa aatctcagga gcagtgggaa cgttcgcaaa tatcccgcca
    28321 tttattgaag agtatgtatg taaacaattg gggatccgtc cacaagaaat ttctactcaa
    28381 gttctccctc gggatctaca tgctgaatat ttctcagcga tggcgcttat tgctacaagt
    28441 attgaacgtt ttgcaacaga gatacgcgga ttgcaaaaat ccgaaacacg tgaagtagaa
    28501 gaattttttg cgaaaggtca aaaaggttct tctgctatgc cgcacaaaag gaatccgatc
    28561 ggttcagaaa atatggctgg tctagccaga gtggtgcgcg gacacatggt cactgcctat
    28621 gaaaatgtca cattatggca tgaaagagat atttctcatt cttcagcaga acgaatcatc
    28681 ttgcctgata ccacgatttt attgaattac atgttaaatc gttttggcaa tatcgttaaa
    28741 aatctaacgg tctttcctga aaacatgaag cggaatatgt ctgcaacatt tggtttgatt
    28801 tatagccagc gcgttatgct gaaattgatc gataagggaa tgacaagaga agaagcttat
    28861 gatcttgttc agccaaaaac tgcgtacgct tgggacaacc aagtgcagtt ccgcccgctg
    28921 ttagaagaag atccaaccat cacatcggta ttatctaaag aagaaataga cgatgccttt
    28981 gattatcatc atcatttgaa aaacgttgac gtgatattca aacgagtagg tttggaataa
    29041 agaagagtga gttgcaaaat tcaattaaaa tagaatagca aaaataacca aaaaagaagc
    29101 agatccgtta gcggttctgc ttcttttagt ttattatatt ttcttatcaa taataggaac
    29161 ctgattttaa aagcggctac ctctttaccg tgcctcttta catacaaaaa atagaggaat
    29221 taagcgtaaa tggcttggct attataacta aaatgctggt tatggagatg ttgcagcaag
    29281 ttttcgagaa aagcgtattc catctcttgt ccattgaata agatctggat acgataatga
    29341 tttttgaaac gcttctgttc atgaatctga ctgattgaaa gttcgccttt gtgttctgtc
    29401 tgataaagaa aagtcctttt acggcattca gcacagcgct tggttgctcg gcggattttt
    29461 cggaatgtat aaaaactagt atctttattg cataaataaa cgtctttgat cgacagcaaa
    29521 tcattatata gacaggaacg ttcttcagct gttaattctg ataaaaaaag ctgaccttgt
    29581 tttattgcat cttccatcgg caagtgcctc ctcgaaccca ttatccaaat ttttagttaa
    29641 ttctaatata ccatcattaa gtataaatgt aaacgcttgt tgatggtata agattttcgt
    29701 ttctgataaa acacgaacat taaaagaatc taatgcctta aatgtacata tttttgttga
    29761 tttataaaaa gatgattgct aaaatttaaa gtgaaaaaac gaacaaaaaa cgatgtattt
    29821 gcttttaatg taaataaaaa ggagagacgt acatggagaa gaaagaactt ttgtatgaag
    29881 gaaaagccaa aaaaatatat cttacttctg atgagaactt gatttggata gaatatttag
    29941 atcaagcaac tgcgttgaat ggcgcgagga aagaccagat aagtggaaaa ggagaattga
    30001 ataatcaaat cacaagtgca attttccgtt atctgactca aagaggaata aaaaatcatt
    30061 ttattgaaca attgtctaaa accgaacaat tagcaaaaaa agtacaaatt atccctctgg
    30121 aagtggttat ccgaaatatt gcagcaggaa gtttctcaaa acgtctaggt gttcccgaag
    30181 gtaaagaatt catcaaacca atcattgaat tctactataa ggatgaccag ttggatgatc
    30241 catttatcaa tgaagagcat atctatttct tacaacttgc aaagccggaa gaaatcagtg
    30301 agctgaaagc ccaagcgttg gctattaatg aaattttgac cgaattattt gctaaggtcg
    30361 gtttggtttt agtagatttc aagctagaat ttggccggtc gaatggacaa attttgcttg
    30421 cggatgaagt aacaccggat acttgccgat tatgggatga acgtacgaat gaacatatgg
    30481 acaaagacgt ttaccgcaga gatctaggtg atttgatccc agtctatcaa gaagtatata
    30541 accgtctatc ggaactaact gaagaaaagg agcgagtatg atgtatttcg taaaagtata
    30601 tgtaacctat aaagattcag tgttagatcc tcaaggggag gcagtaaaaa aagcagtcca
    30661 tcgtatggga tatgaaacaa tcgaagatat ccgaatagga aaatactttg agatacaact
    30721 tgctgatgca gaagaaccaa tcgatacagt gattgaaacg atttgtgaca agctgcttgc
    30781 aaatgtaaat atggaaacat accgatatga aatcaaaaaa atggaggaag tataacatga
    30841 aatttgcggt catcgttttt ccaggttcaa attgtgacgc agatatgtta tgggcagttc
    30901 gcgagatcat gggcgctgat gccgaatttg tacggcatga tgagtcctct ttagaaggat
    30961 ttgatggggt tttactgccg ggaggattct cctatggtga ctatttgaga tgcggtgcga
    31021 ttgctcggtt ttctacaatc atggaagaag tgattcgttt tgctgaagaa gggaaaccag
    31081 tattcggtac atgcaatgga ttccagatat tgacagaagc aggacttttg ccaggtgtac
    31141 tgagacgaaa tgagtctttg cattttattt gcaaaactgt accattgaaa gtcaacccca
    31201 agacggcctt tacttcagag tatgaagccg acgaaataat ctatcttcca gttgctcatg
    31261 gggaaggaaa ttatttctgt gacgaagaaa cacttcaaga actaaaaaaa aataatcaga
    31321 ttgcctttac ttataatgac aacatcaacg gcagcgtgga aaacattgca gggattacga
    31381 acaaagcagg gaatgtgtta ggaatgatgc ctcatccaga acgtgcagta gaagacttgc
    31441 taggatcaga agatgggaaa cggttctttg cttccatttt aaaaaacttc ggaaaggtga
    31501 ccgtatagat gaaaacattg aaagaaccga cagctgaaga gatcaagaaa aaaagaatct
    31561 atgccgaatg gggattgact gatgaagaat atcgaatgat cgaagaagat atcttaggaa
    31621 gaatgcctaa ttatacggaa actggactgt tttctgttat gtggagcgaa cattgttcct
    31681 ataaaaattc taaaccggtt ctacgcaaat ttcctactag tggacctcat gtgttgcaag
    31741 gccctggaga aggcgcaggc atcgtcgaca tcggtgatgg actagcagtt gtcttcaaag
    31801 cagaaagtca caatcatcct tcagccgtgg agccttatga aggagctgcg acaggagttg
    31861 gcggaatcat cagagatatt ttcagcatgg gggctcgtcc aattgcgttg ctagattcat
    31921 tgaggttcgg cgaattagat aatccaagaa cgaaatattt actagaagaa gtagttgcag
    31981 gtatcggcgg atacggcaat tgtatcggca taccgactgt aggcggcgaa attgcatttg
    32041 atccttgtta tgaaggaaac ccattagtca atgcaatgtg cgtaggtttg attgaacaca
    32101 aacatatcca gaaagggcaa gccgctggcg tcggtaattc gatcatgtat gtaggtgcaa
    32161 aaacaggtcg cgacggtatc cacggagcaa cttttgcctc agaagaattt aatcaagaag
    32221 aagaacagca acgttctgct gtacaagtag gcgatccttt tatggaaaag ctgctgcttg
    32281 aagcgtgttt ggaattaatc ttgcatcatt cggattctct aataggtata caggatatgg
    32341 gagcagcagg acttgtttca tctagtgcgg aaatggcttc aaaagctggc tcaggactta
    32401 tattgacatt agatgaagtc ccacaaagag aaactgggat gacaccttat gaaatgatgt
    32461 tatcggaatc acaagaacgg atgttgattt gtgttaaatc aggagaggaa gaaaaaatcc
    32521 aagaactatt tcagaagtat gatctagatg cagtcactat cggtaaagta acagacgacg
    32581 ggcaatatcg gctatatcat caaggagaag aagtagcaaa tctgccagtc gatgcattag
    32641 ctgaagatgc accagtttat cataaagaaa tgaaagaacc agctcgaatc gtagaatttc
    32701 agcagttagc tccttatcag ccagttatcg aagaacctgg acaagtattg cttgatctgc
    32761 tgcagcaacc gacgattgct tcaaaacgtt caatctacga aacttatgat tcacaagtac
    32821 aaaccaatac agttgtccgt ccaggaagcg atgctgctgt gatgagggtt agagggacga
    32881 ataaagcgtt agctatgacc acagactgca acgcgcgcta tctgtatttg gatccaaaaa
    32941 tcggaggaca aatagcagtg gcagaagctg ctagaaatat tattgctagc ggtggtaagc
    33001 ccttggcgat caccgactgc ctgaactatg gttctcctga taaaccagaa gttttttggg
    33061 aattatcgac ttcagctgac ggaattgctg ctgcgtgtga aacgttagga actcctgtta
    33121 tttcaggaaa tgtctcttta tataatgaaa cggatggtca agcaatctat ccaacaccaa
    33181 tgattggtat ggtcggattg attgaggatc ataaacatat cactactcag gaattcaaaa
    33241 aatcagggga tctaatctat atattaggta agacgtttgc agattttgat ggcagtgaat
    33301 tacaaaagat gcagcttgga agaatcgaag gtgtgatccg aaactttgat ctatccattg
    33361 aaaagagaaa ccaagagtta gtattgacag ccatccaaaa cggattgatt gaaagtgctc
    33421 atgactgttc agaaggtggc ttggcaattg cactggcaga atcagctttc aaacatcagc
    33481 tagggatatc tgtacagttt gaattgtcct ctgctcaatt atttgcagaa actcaatcaa
    33541 gatttgtgtt gacagtcgca ccggaaaata agacacgatt cgaagaaatg atgggagatg
    33601 ctgctgtttt agcaggtaag gtgacggatg aagcgataat cgaaatttca gcaactgacg
    33661 gtcagatcaa aatagaaact gcagtagcaa gaaagtgctg ggaggatgca atcgtatgtc
    33721 ttatgaagtg aagagtttaa atgaagaatg cgggatcttc ggtgtttggg gtcatccaga
    33781 cgccgctagt gtggcatact tcgggctcca tagtcttcag catcgaggac aagaaggtgc
    33841 aggtatcgtg tccaatgatc gaggaaagct taaggggcat cgagatttgg ggctgctttc
    33901 tgaggtattc aaagatcaaa gaaaattgca gcagttaaca ggagaagctg caatcggaca
    33961 tgtacgttat gcaacagcag gcaatggaag tgtggacaat attcagcctt ttctattcaa
    34021 atttcatgat cagtcgatcg gcttagcgca taatggtaac ttgatcaatg ctcgttccct
    34081 tagaaaagag ttagaggaaa atggggcgat cttccattct aactccgata cggagatatt
    34141 gatgcatttg atccgacgaa gtgaagaaac agatttttta aataaattaa aaagtgcttt
    34201 gaatgaagtc aaaggtggct ttgcctattt attaatgaca gaaacggcaa tgattgccgc
    34261 tttggaccca aatggttttc gtccattagc aatcggacaa atgaaaaacg gagcatacgt
    34321 gattgcctcg gaaacttgtg cattagaagt tattggggca cgttttataa gagatgtcca
    34381 gcctggtgag atagtgatca tcaatgacga aggaatccag attgattgct ttacgaagga
    34441 cacgcagctt tctatttgtt cgatggaata tatctatttt gccagaccag attcaaacat
    34501 cgcagggatc aatgtgcata ctgcacggaa aaatatggga cggaatttag cgaaagaatc
    34561 gccagtaaaa gcagatatgg tcgttggcgt acctaattct tctttgtcag ccgcaagcgg
    34621 ttatgcggaa gctagtggaa tcccttatga aatcggatta gtaaaaaatc aatacattgc
    34681 ccgaacattt atccagccaa cgcctgagct aagagagcaa ggtgttcgaa tgaaattatc
    34741 tgctgtacga ggagtagtgg aaggtaaaaa ggtgattatg gtcgatgatt caattgttcg
    34801 gggtacgaca agcagacgga tcgtccatct tttgaaagaa gcaggggcaa aagaagtcca
    34861 tgtgaggatt gcttctcctc ctttgaaata tccatgtttt tacgggattg atattcaaac
    34921 gcgtaaagaa ctcattgcgg caaatcacac gattgatgaa atcaaagaat gtatcggtgc
    34981 agattcttta ggttttttaa gtgaagaggg tctgatcgaa tcgatcggtc tggaaaaaga
    35041 tgctccgtat tcaggattgt gtatggctta tttcaacgga gattatccga cgccgttata
    35101 tgactatgaa gaaaaatatc aggaatcact aaaagaaaaa gtatcgttct tttaaaagca
    35161 gaccaagaag ggagtatatg aattcaatgg caaatgcata cgcaaaagct ggcgtagatg
    35221 tcgaagctgg atatgaagta gtagaacgga tcaagaagca tgtcaaaaaa acggaacgtt
    35281 taggtatgat gggcgctata ggaggattcg gcggttgttt tgatttatcg gtctttcaat
    35341 taaaagagcc agtccttgtc tcggggaccg atggcgtggg gacgaaatta gcagtggcaa
    35401 tcgaagcaga caaacacgat acaatcggga tcgactgcgt agcgatgtgt gtcaatgata
    35461 tcttagcaca aggcgcagag ccgttatatt tcttagacta cttagcaacg gggaaaaatg
    35521 atccgttacg tttggaaaat gtagtaaaag gtgtagcaga tggatgtgtt caaggaaata
    35581 tggcgctgat tggcggagaa acagctgaaa tgcctggtat gtactcaggt aatgattatg
    35641 atctagccgg atttgctgta gggatagctg aaaaatctca attattgaca ggagaaacga
    35701 tcaacccagg agatgtgttg cttggaatag catctagcgg gattcattca aatgggtact
    35761 ctcttgttcg caaaattttc tttgagcagc agcagttttc tttatcatca aaactgccag
    35821 aattgaaaaa aacacttggc gaagaattgc ttgagccaac gaaaatctat gtttcttcct
    35881 tgcttccgct gatcaaagaa aagaaaataa aaggagctgc acatatcact ggtggagggt
    35941 ttgtagaaaa tatcccgcga atgttaccag aatctatggc tgcacaaatc aaacttggct
    36001 catggccgat tcttccaata ttcggctgtt tacaaaaata tggtgaaatt cctgagatgg
    36061 agatgtatga aatcttcaat atgggcatcg gtatggtcct ggcagtcgaa gaatcgaaag
    36121 taaaagaaat agtacacgaa attgagcaag ctggcgaaaa agtttatgaa atcgggaaag
    36181 tgatcgccaa agaaaaacat cgtgtggtgt ttataggaga agaacgatga gaatcgctgt
    36241 ttttgcttct ggaaacggaa gcaactttca agcgctagcc gattatctat cgaaaaaagg
    36301 attggaatct tcgattgact ggttgttttg tgatcagcct gaagcatatg ttttgaaacg
    36361 tgcaactgcg ttgagtgtac cggcagattg tttttcacct aaagaatttg attcaaaaaa
    36421 agagtatgaa gaagcaattt tgcataaatt gaaagaaaaa aagatcgatt tgatcgtatt
    36481 agctggatat atgcgaatca ttggaccggt attgctgaaa aattatgata aaagaatcat
    36541 caatatccat ccgtctcttt tacctgcctt ccctggtttg catggcatac gtgatgcctt
    36601 tgaagctgga gtaaaagaaa cgggtgtcac aattcattat atcgaccaag gtgtagatac
    36661 tggaccaatc atccggcagg aaaaagtgag aattgaacag gaggacacgt tcgattcttt
    36721 agaagaaaaa atccatagag tagagcatcg aatctatcca gaagtgatta gtgaaattat
    36781 tgaaaatgga ggctatctga aatgacaaga gcattgatca gtgtatcaga taaaactggg
    36841 attgtagcat tcgcccaagg tttgattgaa caaggagtag aaatcatttc aacaggagga
    36901 acaaagcatg cgttggataa agctgggatc aaaacgcttt cgatcgaaga agtgacaggg
    36961 tttcctgaaa tgatggatgg ccgtgtcaaa acacttcatc ctaaaatcca tggtggtctt
    37021 ttaggaagac gcgatctccc tagccatatg gaggcaatgg aaacggaaaa tatccaacca
    37081 atcgactttg tttgtgtcaa tttatatcct ttcaaagaaa cgattatgaa accagatgtc
    37141 gaaatagcag aagctattga aaacattgat atcggtggtc ctagtatgct ccgtagtgca
    37201 gcaaaaaacc atgaatttgt cacctctgtt gttgatccat ctgactatga agaagtactt
    37261 tcagaattac gtcagtatgg gcatacttca ctttctttca gacaaaaact agcggcaaaa
    37321 gtctttcgtc atactgcggc atatgatgca ctgatcgctc aatacttaac ggattgggtg
    37381 gaagaaaaag aaccggaaaa attgacactt acgtatgaac gaaaacaaac gcttcgttac
    37441 ggtgaaaata gccatcaagc cgctgccttt tatcagtccg ctcttctgga aaaatattcg
    37501 atcgcagcag caaaacaact ccatgggaaa gaactttctt ataataatat ccgagatgca
    37561 gatgctgcgc tacggatcat gaaggaatat gacgagccaa cggtagtcgc cttgaaacac
    37621 atgaatcctt gtggtattgg gacagcatct acgattttag aagcgtggga agcagcgtat
    37681 gaagcagatc ctgtttcaat ctttggtggg atcatcgttt tgaatcgaga agtagatctg
    37741 ccaacagcag aacagatgca taagctgttt ctagaaatca tcattgcccc ttcttataca
    37801 caagaagctt tggaattact gcaaaaaaag aaaaacatcc gattactgac agtagacttt
    37861 gcgcaggaag aaaatcaaaa tcgagaagaa acggtctcag tcttaggtgg acttcttgta
    37921 caagatcaag atctggcaat agaaaatgaa gaagagtgga aagtcgtgac aaaacgtaag
    37981 ccgactccag cagaagcaaa agcattagtg tttgcttgga gagctgtcaa acatgtgaaa
    38041 tctaatgcga tcgtactggc aaacgaacgt cagacagtag gaatcggagc cgggcagatg
    38101 aatcgagtcg gttcagtaaa aattgcgatt gaacaagcgc aagagaaaat ggaaggtgca
    38161 gttttagcta gcgatgctta ttttccaatg gatgattcgg ttgaatatgc agccaaacat
    38221 ggtataaaag caatcattca gccaggagga agcatcaaag accaagattc tattgatatg
    38281 gcgaataaat acgatctagc aatggtcttt actgatgttc ggcattttag acattagaga
    38341 ggagtcggat aaatgaacat tttggtgatc ggtgcaggtg gtcgtgaaca tgcaataagt
    38401 aaaaaacttt tagccagtcc gaaggtggat acggtgtatt gtgcgccagg aaatccgggg
    38461 atgacaaaag atggtatcaa ttgtgtcgct atcagtgagc gagatcattc agcgttaatc
    38521 cattttgtta agaaagaggc tattgattgg agtatcgttg gtcctgaagt tcctttgtta
    38581 aatgggatcg tcgatgattt tatggcggaa ggattgaaaa tcttcggtcc gacaaaagca
    38641 gcagctctga tcgaaggttc gaaaagtttt gctaaacaat taatggatac ttatcaaatc
    38701 ccgacagcta aatccagaag ttttgaatgt tacgaaaaag cagcagcgta tatcaaagaa
    38761 aatggtgcgc caatcgtagt gaaagcggac ggcttagcag ctgggaaagg tgtagtcgtg
    38821 gctaccacag tgaaggaagc gctggatgcg gcagaacaaa tgttgaacca gcatcgattt
    38881 ggggatagta gcaaaaaaat cgtcgtagaa gagtttttgg caggagaaga attctccctt
    38941 ttggcgtttg tccgtaatac caaggtgtat ccgatggtca tttcgcaaga tcataagcgg
    39001 gcatttgata acgataaagg gccaaataca ggcggaatgg gtgcttattc accagtaccg
    39061 caaatttcaa aaaagatgat tgaaaaagct gtggaagaag ttttaaaacc agcggctttg
    39121 ggaatgaaag aactaggacg ctctttcacg ggtgttttat atgcgggttt gattgctacg
    39181 aaggaaggac caaaagtgat cgaattcaat gcgcgtttcg gtgatcctga aacgcaagtc
    39241 gttctttctc ggttgaagag tgactttgcg caagtaatcg atgatttatt agagaatcgt
    39301 acagtagagt taaagtggca gcaagaagga tacaatgtag gcgttgtggt tgcagctgcc
    39361 ggttaccccg aagaatatga gacaggaatg gttctaccag attttctgga agaagagctt
    39421 tctgtttact atgctggagt ttcctcaaat aacggcaaac tagttggagc aggaggacgt
    39481 ctttatttag tagaagcata cggtgagacg atcaaagaag cacagaaaaa aatttacacc
    39541 gcgttaatgg ataaaacgac agatggaaca ttttatcgta cagatattgg agaaaaagct
    39601 gccaatagcg aactgatcgt gaagtaaatc agctgcttcc atttataaaa aatacaacaa
    39661 acataatcgg aagcgccgat tttagtgaag ccttttcata aagagtgtgg tacacttttg
    39721 ttgtgtatat aaataaggag gagttcagat gaaaaaaatt caattaggta cttctgatca
    39781 gaaagcagct gcagtgatct taggctgtat gcgtatcaac aatgcggaag atccagtaaa
    39841 agtgattgag acagcttatg aaaacggcat tgattttttt gaccatgcag atatttatgg
    39901 aaacggtgaa tgtgaagaaa tctttgcaga tgctctagca aaaacatcaa tcaaacgaga
    39961 agatcttttt attcaaacaa aatgtggaat cgttccaggt gtgatgtttg atttttctaa
    40021 aaaacatatc attgaatctg tagaaaaaag tttgacccgt ctgaaaatgg attatgtgga
    40081 tgctttactt cttcatcgtc cagatacatt ggtagaacca gaggaagtag ctgaagcgtt
    40141 tgatgaattg gaacggtcag gaaaagttcg ttattttggc gtcagcaatc aaaaaccaat
    40201 gcaaatcgaa ttgctgaaaa aatatgttcg tcaaccatta gtagctaatc agctgcaatt
    40261 tggcttgaaa catactggaa tgatcgatca agggattcat gtcaatatga cagatgaagc
    40321 aagtatcgat catgacggta gtgtacttga ttattcccga ttgcatgata tgacgatcca
    40381 agcatggtca ccataccagt atggattttt tgaaggtgta tttatcggga acgaaaaatt
    40441 ccctgaatta aaccaaacat tagaagaact agcagctaaa tatcaaacga caccaactgg
    40501 cttggcttct gcttggattt tacgccatcc agccaatatg caagtgatcg ccggtacgat
    40561 gaacgtaggg cgaatcaagg aaatcgctca agcttcagaa attaatatgt ctcgggaaga
    40621 ttggtacgaa ttgtaccgtg ctgctggaaa cattttacct taaagattgt cataagcagg
    40681 tcaaaagggc tataaattaa aaagacagaa taacttgaaa gctgttttca gcttcgagat
    40741 attctgtctt tttttattgc aaatggaaag agtatcattg tacggatttc gtttattagt
    40801 tatttttgtt tttaaggaaa agctgtgtcc gatattcttt tggagaaatc ccttgttttt
    40861 tcttaaataa ataactgaaa tagttagggt cattataacc aatttcaaaa gcaatatctg
    40921 aaatacgata gtctgattgc tgcaataatt tttttgctaa ttcgattctt tgttctgtca
    40981 gataatcgat gaatgtttgg ttaaacgatt gagaaaaaat cgtactgaaa tgagagggac
    41041 ttaatgcaac ttgttgagcg acccaagtta aggacatatc tggatcggta aaattttctt
    41101 tgataaaatc caatgcatgg ttcaaaattg gctgatattt gttccttgaa ggctgtgagg
    41161 gcagagcagt taagaaagaa atgaacatat aaactgtcga acggtaaagc gagtcgtcgg
    41221 cgctgattgc taagcgttga ctggtggatg tgcaatgaac catttcttgc gggattttct
    41281 tttctttcag gcagacatgc tggagtagct tagtcaagac aaataaacga tataatcgtg
    41341 ttcgagttgg tgtgccttgt ggtttcgtca agtgttcgat gtacttagat acttcgtttt
    41401 tcgataatga agacaaatca agtgagaggt caaagtaaaa gacagaatca actggaagtt
    41461 tcgcttcttg aatcaaatcc tcatagctga taatttgttc tttaagggaa ctggcggttt
    41521 caagtatcat ctgcgtgatc tcaaaagatg caggtaattc gctgattctt tctgcgacag
    41581 gaccaatggc gacagaaaaa ttattttttt gtcccttttc taattcatgg accaacgttt
    41641 gggctacctg ataactggtc tcgatcacat tttcttcaag agaatcaact attaaaaatt
    41701 tgatgaatcg agaggaaaca gcagagaaga tcacttgttg attctcccta aataaaaact
    41761 tcaaataatc actgagatga gcgtaatctt caaagtctgt actgacttgg tttgctgcta
    41821 ataatacggt catttttttc cctgctaaag agcgattgaa agattcagca agtttcaatg
    41881 tttcactgat cgtaagtgag cctttgaaca aaccgttcaa gaaatgattt tttttcaatt
    41941 cgaaaacaag atcagaagaa gtgtgcgttt ctttttgctg caaatctaaa gcagttactg
    42001 ctttttctat tgcttgtttc aattcgctac ttttaatcgg tttaagcaga taatcatctg
    42061 cctgtacctg gattgctcct ttcatataat cgaaatcgtc gaatccacta ataaatatga
    42121 gacgagtcca aggaagtagt ttccttgctt cttttgaaaa agtcaacccg tccatgaaag
    42181 gcatttggat atcagtcaga atgatgtcgg gctgtaagtc gataattgaa gacagtgcca
    42241 tctcaccatc tccagcttcg ccgacataag tgattggata ataagaacca aggacagtta
    42301 tttgttcccg caagttattg cgaatgaggt attcgtcttc gatgataaaa actttataca
    42361 tgtttgtttc ctccaattgt tttgggagat agagggatca tcagtgtgac agttgttcct
    42421 tctcggtatt tgctgtcaat cgtgataggt ttttgatcat ttccgtaata aagaaggaga
    42481 cgcttgttta cgttgtaaag tccgtagccg atactgaaat ctgaatcgat ccctttggct
    42541 aactctttac gtatttctgc cagtttttct gcagggatgc caatcccgtt gtctataact
    42601 ttgaattgga tcatctcatc aattttgcat gtggtaatac gaataaatcc tttgtgacgg
    42661 acgtacttcg ttccatggta tacagcattt tcaatcaatg gctgcaagat catttttaaa
    42721 atagaaacag gaaaaagtgt ttctggtata tcgatcttat agtcaagcat atggccgtat
    42781 cttattttta agatgactag ataatcattg atatggctaa tttctttttc aagaggaatc
    42841 cagtcttgtc ctttgcttaa agacgtacga aaaaagccgg aaagtgcatg ggtcatagtc
    42901 agagcttctt caaagcagtc ttgttcgatc aaagaaataa tggcatccaa actgttataa
    42961 ataaaatggg gagtaatctg agcttgcaat acacgaactt cactttgtgc taaatggtat
    43021 tgtttcaaag cgttctcccg taaagactgg tttagatctt ccgccatttt attcatgcta
    43081 gcggtaagtg tttgtaattc cagtgtttcc ggcagggtta aacgaaagcc aaggttccct
    43141 gaagaaagtt gttctgacat ctcgatcagc tgattgatcg gttcttggac ctttctctct
    43201 aaaaagcgac gattcttttt cgcatagaaa aaaatggtac taagaactcc aagttccact
    43261 attgttaata gaatgagcga gcggacaagt gtcgtatttt ttttgcttgc taagtcgatc
    43321 tccacacgaa caaaatcttg taagatatct gacagcagtt gagtgacaga atctacctga
    43381 ttgatgatct cttcattggt atccataaaa tcttttgcca agatattatt gatcagctcg
    43441 ttttgataat cttccagtgt atcgatcgta cgtagcgata catctaacgt actaatttct
    43501 ttaagtgtat ttgtattatt tttgatctct cgaatatcat tcctaagttc ttctaggata
    43561 ttttcctcat tgaactcatc tacggttact tggccagaaa tcaagtccca catactttcc
    43621 aaaacttttt gatcaacctt caaagcaatt gcatctgctt tttggatatt tgcgatcgtc
    43681 tgttgataaa tcaaaagctg ttgcgaatat aacagtatgc tcagtagcaa agggataaca
    43741 gcaaatagaa gcatggcttt gtttgcttgg gcaaaaatct gttttatgct taaatttttt
    43801 gtcatgatac ttctccagtc aataatttct ggttgggatg ttagctatat tctgctggga
    43861 aaagacagtc tcggaaataa aaatatcttt aggtaatgtt tttcctgttt gaatatttcc
    43921 aaaataacga gtaacggtat tggctacata ccagccgaca tcaggtttac actcgactac
    43981 acaattgacg attcctgagc gtagcttctc gatcatatct tcttgtccat caatagttac
    44041 aatgatcaaa tcttctccag gtttgattga tgtttctttt atcgcagcta aagcaccgtg
    44101 agtcatttca tcactatggc tgtataatac atcgatttcg gataaatcat ttgtttctaa
    44161 atatcgtttc atctggtctt ttcctttcat ccgaataaaa tcaccgacaa ttcggtgaac
    44221 aatagtcatc ggaggtttat ggtcgatggt tccatctttt tttagggttg gtttacgatt
    44281 gattgattcc aaaaatcctt cggagcgtag cttggtcggt gtggagttct ctgaaccagc
    44341 aagttctagg attctgattt cctgtttctt tgaatttgtg aagtgattgc tgacaaataa
    44401 acccgcccga tttccttctg ctttgaaact ggggccaatg tgggtgacga aaagctcggg
    44461 atcattcgtt tgaatatgtc tgtcgacaag tatgacaggg atccctgctc gctttgcttc
    44521 ttttaataca gagtcccacc cggattcttg caaaggagta aaaatgatca tatccacttt
    44581 ataggcaatg aacgtccgta tatcttggat ttgccgttcc tgattcatgt agccatttcg
    44641 gtagagaact tggtaatctt ctttttcaag cgcagtgata attgattcag tatgcttttt
    44701 ccgccagcta ctctccgttc ctgattgcga aaaaccaacg actagtgggt caggtgcttc
    44761 ctttgtatta ggtgtacacc ccatcatttg gtaagcgatt acaacaaggg ctaaaaaaaa
    44821 taaaacacgt ttcactttaa atcactccat ctggatttgt tagtactatc ttatcagata
    44881 aaagggaaaa tcaaagtcaa aaggaatcaa tcgaaaaaaa tccaagaaac ttaaaaaaat
    44941 ccaagacaaa aaaagtacac ctaaaaaatt taaagtaaat cccataaaaa aatcaatgtt
    45001 aacgctttct ttattagcta tactcggtgt atcaattgaa atgggggata aaaaatgaaa
    45061 aacaaattta gaaagattgt tgggactatc gctattttga ccgcaagcat tctattaagt
    45121 gcgtgtggca attcaggatc tgcagatgat agtacggggt atgtaggaat cgctatgccg
    45181 accaaatcag cagaaagatg gatcgctgat gggaacaaca tggtctcgga attagaaaaa
    45241 ctgggttata aaacagatct tcaatatgga gaagataaag tagaaaatca agtagcacaa
    45301 atagaaaata tgattacaaa aggggtagat acacttgtga ttgcttctat cgatggttcg
    45361 gctttaactg atgtgttagc taaagcaaaa gaagcagata tcaaggtgat cgcctatgat
    45421 cgtttactga tgaattcaga aaatgtcgat tattgcgcga cttttgataa ttttggagta
    45481 ggtgtatcgc aagcagctta tattgaagag cacttaggat tgaaagaagg aaaaggacca
    45541 ttcacgattg aattatttgg tggctcgcct gacgacaaca acgcactaat caattacaac
    45601 ggagtgatgt ctgttttaca accatatatg gacaacggtc agttggtcgt gccatctgga
    45661 cagacgagtt tcagtcaaat cgctacgctt cgctgggatg gttctacggc gcaagcaagg
    45721 atggataatc tgttaagcgc aaattatact gaccaaacat tggatgctgt tttgtcgcca
    45781 tatgatccaa taagtttagg aatcatttcg tcattaaaag gcgtggggta tgggagtgaa
    45841 agtaaacctt tacctgtgat tactggacaa gatgcgacag ttgctggcgt taaatcgatc
    45901 attgccgggg aacaaacaca aacgatcttt aaagacacac gtatcttagc aaaaaatacg
    45961 attgaaatga tcaaagcaat cagtgatgga gaagaggttc cggtcaatga tactgaaact
    46021 tatgataatg gggtgaaaac tgtccctacg tatttagcaa atacagtatc tgtcgataaa
    46081 gataattatc aagcagagct gatcgacacc gattattata aagaatccga tctgaaaaat
    46141 taagaggaac caaacaagga actaaagaga tctaagtcag agagaggata agaattatgg
    46201 cggattgtat tttaaaaatg gcagatatca ccaaaaaatt ttctggaatc cgagcgttag
    46261 attgcgtgaa tctgatgatt gaacgtgggg aaatccatgc attgtgcgga gaaaacggag
    46321 cgggaaaatc aacattgatg aatgtcttga gcggcttgta tccatatggc tcctatgacg
    46381 gggaaatctt ttatgatgga aagctgtgtc aatttaaaga tttgaaagat agtgaagaaa
    46441 aaggcatcgt catcattcat caagaattag cactaagtcc ttatctttca ataaaagaga
    46501 atatttttct cggaaatgaa caagcagaaa gaggcgtgat tgattgggaa ctgacagaaa
    46561 agaaaacata tgaactgctg aataaagtcg gtttgtctat cgacccgaat cttctagtat
    46621 cccagattgg cgtagggcaa cagcaactag ttgaaatagc taaagcatta tcaaaatccg
    46681 tccgtctgtt gattttggat gagcctaccg ctgcattgaa tgaagaagaa agcgcgaatt
    46741 tgctgagatt gatccgagag ttgaaagagc aaggtgtaac ctccatcatt atttcacata
    46801 agctgaatga aatcgtggat atcgcagatc gaatcaccat tttacgggat ggacagacga
    46861 ttgagacact agaaaatgaa atgatcagcg aagagcatat tattcgcgga atggtgggca
    46921 gagatttagt tgatcgttat cctgaaagaa aaccggatat tggagaagtt tattttaaag
    46981 tagaagactg gacggtctat caccctcttg atcacgagcg aatcataaac gaccacatca
    47041 acttgcattt gaaaaaagga gagattgtag gaatagctgg actgatggga gcgggcagaa
    47101 ctgaattcgc tatgagtcta tttggacatt cttatggaag caagatatcc ggacgtatat
    47161 taaaggaagg ggcagagata tcagttaaga ccgttccttc agccattgca aacggactcg
    47221 cttatgtctc ggaggaccga aaatctttag gactgaatct gctgatggat attcgggaaa
    47281 acgtgacgct gagcagtttg gataaaataa gtcaaaaagg agtattagat aaagaaaaag
    47341 aagtaactga ggcagaaaat ttccggaaaa agatgcgtat aaaaacaaac tccatccatc
    47401 aaattgtcag tagtcttagt ggtgggaatc aacaaaaagt cgttttatcc aagtggctga
    47461 tgacacaacc cgatattctt tttttggatg agccaacccg tgggatagat gttggggcaa
    47521 aatatgagat ctacacgatt atcgaagaaa tggcagcaaa tggcaaagct gtctgtctta
    47581 tctcttctga acttcctgaa atattaggga tgtgtgatcg aatctatacg atgaacgaag
    47641 gacgtattac aggagaagtc tcgcgagaag atgcagatca ggaagtcttg atgaaattaa
    47701 tgacgaaaga agaggtgggt taagttggaa caggcaaaaa atcttacgga taaaaaagag
    47761 aaaaaactaa atttgaaaag tagagcagct gatctttttg gtcgctacag catggtgatc
    47821 attttagcgg gactacttat tgcgtttcaa ttgatgacgg atggtatttt ctggcgtcca
    47881 ttgaatataa ctaaccttgt tctgcaaaat agccatatat tagtactagc tgcagggatg
    47941 ttattagttg tgctcttagg tcatgtggat ttgtcggtag ggtcagtgat ggcgtttgtt
    48001 ggtgcaattg cgggcatgat gatggtcaat cgccaaatga acccgtggat gacagttatc
    48061 gcatgtcttg cagtaggcgg gctgatcggc gcatggcaag gtttttgggt agcttatgca
    48121 gggataccgg cgtttatcgt gactttagca ggattgctga tgtttcgtgg actgacacaa
    48181 gttgttctag gaggccaatc tctagcacct tttccagctg ttttccaaaa aatgtctacg
    48241 ggttatttac cagacttaag cgaaggaagc agccttcact tcttgacatt gattttagga
    48301 atgatcatca cgatcgtgtt agttgttggt caatggcgaa caagaaatcg tcggaaaaat
    48361 catttatttg aagtggaatc tccaacagct ttcttggtaa aggcggtatt tacagcagtc
    48421 gttgtactag gaataactta tatctttgcc tcttatcaag ggtatccgat tattttgatc
    48481 attcttggtt tgatcgttgc agcatatggg tttttgacaa ataaaacagt agcaggtcga
    48541 cagatttatg cgacgggcgg aaatcgaaaa gcggctgaac tatcagggat caaaacaaag
    48601 cgaatcacgt tctgggtatt cgtcaacatg ggagtcatgg cagctttagc tggattagtt
    48661 ttagctgctc gattgaatgc ggcaacacct caagcaggta catcgatgga actggatgca
    48721 atggcggcag tatattttgg tggtgcttcg acttccggcg gcattggaac aatcatgggt
    48781 gcgattgtcg gtggcttggt catgggtgta ttgaacaatg gcatgtcgat tttaggcgtc
    48841 ggggtagact ggcagcaggc aatcaaagga ttgatcttgc ttttagccgt tgtgctagac
    48901 ttgtataata agaaaaaacg aacaacgtag gagaacgccg gttattcaga aaaaagactg
    48961 tgacaagaca tttgtcacag tctttttttc gctaaaagcg aacattcatt gtttcgtttg
    49021 tatagactaa aaataatata tgttttttta ccattcgtat aaattctctt tttgctcttg
    49081 atttttttgc ttaattgagt taaattacat agggcgctaa aaaaagcctt gattaaatta
    49141 ataatgttcg tgttttgctg gatgtgaaca tcaggaggat aatgtaatga aagtatttga
    49201 ttacgaagat attcaattaa ttcctaataa atgtatcgta aatagccgtt ctgaatgtga
    49261 tacaacggtc acattaggta aacatacatt caaaatgcca gtagtgcctg ccaacatgca
    49321 gacgattatt gatgaaacaa tcgcagaatt cttagcggaa aatggttatt tctatatcat
    49381 gcatcggttt gatgaagcag ctcgaattcc gtttatcaaa aaaatgaaaa agcgtggatt
    49441 gattacctcg atcagtgttg gcgtcaagaa agaggaatat tcctttatag agaagttggc
    49501 agaagaatcg ctaaatcctg attatatcac tatcgacatc gcgcatggac atgctaactc
    49561 agttattgat atgattcagc atattaaaaa atatttgcct gaaacttttg tgattgccgg
    49621 taatgttggt acaccggaag ccgtccgtga attggaaaat gcgggcgcag atgcaacaaa
    49681 agtcgggatt ggtccaggaa aagtatgtat tacaaaaatc aagacaggct ttgggactgg
    49741 aggctggcaa ctggcagctc ttagatggtg tgcgaaagca gctcgcaagc cgatcatcgc
    49801 tgacggtggg atcagaacac atggcgatat tgcaaaatct gtccgttttg gtgcgacaat
    49861 ggtcatgatt ggttcattgt ttgccggtca cgaggaatct cctggcgaaa caaaagtcga
    49921 aaatggaatc gtgtataaag aatactttgg ttctgcttca gaattccaaa aaggcgaaaa
    49981 acgaaatgtt gaaggaaaga aaatctggat ccaacacaaa ggatctttga aagatacact
    50041 agtggaaatg caacaagacc ttcaatcatc tatttcttat gctggaggaa gagatctgga
    50101 agccattcga aaagttgact atgtcatcgt gaaaaattcg atttttaatg gagacacaat
    50161 ctaaaaaata aataaaatat taggatgttg tgaaaaagtt gtcctgcatt aagtaataag
    50221 aacagccaaa caaaaatagt tctttatatg ttttgtttgg ctggaattat tatcgcagat
    50281 acaagctttt gaacatcatt attcagaata agggactgtg ataagatttt tgtcacagtc
    50341 ccttatgttt tgcaaaaaaa gtttttcttt tttctcgtaa attcggtaaa atcaaaagaa
    50401 aaaatagaca atagaaaaga gaagcttatg tgggaaaaag tagagaaaaa acaaggaccg
    50461 atttatcgtc aaattatgga acagattatg agagaaatcg aaaacggaag gatcaatcct
    50521 ggaagtcaac ttgaatcaga acgaaaacta gggcaacttt ttggtgtgaa tcgttccacc
    50581 gttgtccatg cattggaaga gcttagggag cttggggtac taacgagcaa acgtggcagc
    50641 ggatggtttg ttaatcagac tgaatggggg aaattcgctg ttccaagaat cgattggcgg
    50701 caaatgatct ctcctcgtta tgagcagacg gactggtatg agcaaaaaat aagagaagca
    50761 aagcagatcc aaaaaacatc gtttcttgat ttatacgcta gcgagatgcc agatgagctt
    50821 ttgccgaatt ttgagtttcc ttcttattct cttgaagaaa tcttagcgga agaaaaagaa
    50881 atggatcttt taggctatac tccgttacgt aacaaaatca aacggtattt ggaaagtaaa
    50941 tttgaattgg cattttcccc caaccagctt cttgtgactg gtggcggtca gcaagcaatc
    51001 tttttgattt tacaaacgat tctttcagct ggagagggga tagctgtaga gtcaccttct
    51061 tttttttacc gattacctct tttcaaagct tcaggaacgc gtttatttgg gataccgatg
    51121 gatgaagaag ggatcgactt agaaaaactg aaagaatcga tccataaaaa taaattgaaa
    51181 gcagtgctta tcaacccgaa ttttcaaaac cctacaggaa aagtgatgag tcaaaaacga
    51241 cgagaaaagc tagtagaatt gtgtcgacag tatcggcttc caattattga agacgatgta
    51301 tttacggatc tttcatttct aaaccaagaa gaagtccttc ctatacgaac gattgatccg
    51361 gataatgtgt tatacgtcgg ttcgttatct agggttttag gaaaaacaac gaaaatcggt
    51421 tgggtgatag gacctgagac ttttatctcg caactagctc aagcgcaaga aatgatggag
    51481 ttttcgatga atatccttac acaaatcaca gtggctaatg tatttaatga agcaattgat
    51541 ttgaaaatgc aagatgtaag aaaaaagttg aaagaaaaaa gccgactgat aagcgcttgg
    51601 ggagattcac aatcgttttt caagcttcat tcaattttag gtggttacta tgcctggatt
    51661 acttgggatg ggaaaaaact agaccccgaa ctagcagaaa aagtagtaga tatgggtctt
    51721 ggaattgcac caagtctact ttttgggcaa gatataaatg gaatcagaat caattacagt
    51781 aggctggatg aaaaccaaat accgttgttt tattcaaaga tgaaaattct agaaaagtgg
    51841 ttaacagaat aatttcacaa agtaaataga ttaaagaata taacagcttg gatttaaatt
    51901 tcaagctgtt tctttttttt cggaaaaaga atacgatata aagaaactaa gaaaaaacca
    51961 ttatttgtac gtccgttcac gatgtgtaaa taaaataaat gtttgcaaca aaactgtata
    52021 acaccaacgt ttttaaatag aaacagatgg ttgtaagttt gattagaaaa tagaaaaaat
    52081 gcagatgaaa tataaaacgc tttccttatt gtgattttat tcactaatgc tgttaatatg
    52141 cggattggca taatttcctt tcatcgtgaa aatttgtgct tttagcttgt atttctcata
    52201 aatccatgat aatttattaa tgaagacggt taaatagtga tacagtttta ttcactgttt
    52261 caatcgcaga atgaagagat tttcttatag atgagagagg aatgtgtgac aaatggcaaa
    52321 caaaaaagca ccgatcgact tccaagcact gctagatgaa gtcaatgcag atttcccagt
    52381 atatcaagca cttgatcaag atggaaacgt agttaacaaa gatttagtac ctgatttatc
    52441 cgatgatgaa ctcgttgaat taatgactca tatggtatgg tctcgtgtat tagaccaacg
    52501 ttcaacagcg ctgaaccgcc aaggacgcct aggctttttt gcaccaactg ctggacaaga
    52561 ggcaagtcag ctggctagtg cttacgcatt tgataaagaa gatgttcttc ttccaggtta
    52621 tcgggatgta cctcaactag taaaacatgg tttaccttta tctcaagctt ttttatggtc
    52681 tcgaggacat gctgcaggta attcttatcc ggaagaattg aaagctctac caccacaaat
    52741 tatcatcggt gcacaatatg tacaagcagc cggtgttgca ttaggtttga agaaacgaaa
    52801 caagaaaaat gtcgtcttca cttatactgg tgatggcggt tcatcacaag gtgattttta
    52861 cgaagcaatc aatttcgctg gcgcttacca tgcaaatgcc gtattttata tccaaaacaa
    52921 cgggtatgcg atctctacac ctcgtgaaaa acaaactgca gcaaaaacac ttgcacaaaa
    52981 agctgtcgca gctgggattc ctggtattca agtcgatgga atggatccgc ttgcagtata
    53041 tactgtatct aaaatggcac gggaatgggc gatcagtgga aatggaccag tcctaatcga
    53101 aacactgact tatcgttatg gaccacatac actatctggt gacgatccaa cccgctaccg
    53161 tacaaaagac acagatgacg attggcagaa aaaagatcca ttgatccgct tccgtaaata
    53221 tttgacggaa aaaggacttt ggtctgaaga aaaagaagaa caagtcatcg aagcaactaa
    53281 agaagaaatc aaagcagcta ttgctgaagc cgacaaagta ccaaaacaaa aggtttcaga
    53341 tttcttgaaa aacatgttcg aagtatctcc acaatcaatc aaagaacaaa ttgcaattta
    53401 tgaagcgaag gagtcgaaat aatcatggca caaaaaacaa tgatccaagc aatcacagat
    53461 gccttagcac ttgaactaga aaatgacgag aatgtcgttg tttttggtga agatgttggg
    53521 aaaaacggag gagttttccg ggcaactgaa ggattgcagg aaaagttcgg agaagaccga
    53581 gtattcgata ctcctttagc tgaatctgga atcgcaggat tgagtttcgg tcttgcgtta
    53641 gaaggatttc gtccagttcc tgaaatccaa ttctttggtt ttattttcga agcaatggac
    53701 gaagtagtag ctcaaatggc tcgtacaaga tatcgaatga gcggcactag aaatctaccc
    53761 atcacaattc gttcgccatt tggtggcggt gttcatacac cagaattgca ttcggataat
    53821 ttagaaggtt tgatcgctca gtctcctggt attcgagtag tgattccttc caacccttat
    53881 gatgcaaaag gactattgat ttcttctatt agaagtaacg atccggttgt tttcctagaa
    53941 cacatgaaac tatatcgctc attccgagaa gaagtgccgg atgaagctta cgaagttcct
    54001 ttggataaag cagcagttac tcgtgaggga acagatgtat ctattatcac atacggagca
    54061 atggtgcgtg aagcaatcaa agcagcagac aatcttgcaa aagaaaatat atctgttgaa
    54121 atcattgatc ttcgtacagt tgcgccatta gatgtagaaa cgatcattca atccgtggaa
    54181 aaaactggtc gcgtagttgt tgtccaagaa gcacaacgac aagcgggcgt tgccgcgcaa
    54241 gtagtttctg agatctcaga acgcgctatc ctttcattag aagccccaat cggacgagtt
    54301 tctgcacctg atacagtctt cccatttgga caagcagaaa atgtctggtt gccaaatgca
    54361 aaagatatcg aagacaaagt aaaagaaatc gcggaatttt aagaaaagaa gggacgaaac
    54421 aaagtcatgg cttatcaatt taaattgccg gatatcggtg aaggaatcgc agaaggtgaa
    54481 atcgtcaaat ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa
    54541 gttcaaaatg acaaatcagt agaagaaatc ccgtcacctg ttacaggaac ggttaaaaat
    54601 gtgattgttc cagaaggtac cgtagcaaat gttggggatg tattagtaga aatcgatgca
    54661 ccaggacacg aagacaatga aggggacagt ggtgtagccg cagaatccca aactccagct
    54721 aaaccggctg ctgaacccac tgttgataca gaatcagctg gatcgtcaag cgaaggagtc
    54781 ttccaattta agttaccgga tatcggtgaa ggaatcgcag aaggtgaaat cgtcaaatgg
    54841 ttcgtcaaac caggagatac gatcaatgaa gatgatacat tactagaagt tcaaaatgac
    54901 aaatcagtag aagaaattcc gtcacctgtc acagggacag ttaaaaacgt gattgttcca
    54961 gaaggcactg tagcaaatgt tggggatgta ttagtagaaa tcgatgctcc tggacacaat
    55021 agtgcaccgt caactagtgc gccatcagct gaagcaccaa aagaaaaagt ggaaacatca
    55081 ggttcagcaa gtgtcgttga agctgccgat ccaaataaac gtgtattggc tatgccatct
    55141 gttcgtcaat ttgcccgtga aaaagatgta gatatctcac aagtaactgc aactggaaaa
    55201 ggtggcagag taacaaaaga ggacatcgaa aacttcttgg caggtggtcc aagcagtgca
    55261 ccagcgaaat cagaagcgcc agaagcggca gcaccgaaag aagcagctcc tgcagcagaa
    55321 agcaaaccag ctgcaccagc aaaaccattc aagtccaact taggagactt ggaagaacgt
    55381 gtagcaatga cgccaacacg taaagctatc gctaaagcaa tggtcaacag taagcataca
    55441 gctccacacg tgacattgca tgatgaagta gaagtgtcta aactatggga taatcggaaa
    55501 cgatttaaag aagttgctgc tgcaaatggt acgaaactta ctttcttgcc atatgtcgtg
    55561 aaagctttaa cagcgactgt taagaaatac ccagtattga atgcatctat cgacgatgca
    55621 aaccaagaaa tcgtttataa acattactac aatatcggta ttgcaactga tacggatcac
    55681 ggactatatg taccaaatgt gaaagatgca gaccgcaaag gaatgtttgc tattgcagac
    55741 gaaatcaatg agaaagcaaa attagctcat gacggcaaac tatctgcaga agatatgcgc
    55801 aatggaacaa ttacgatcag caatatcgga tctgtaggtg gcggttggtt tacaccagtc
    55861 atcaactatc cagaagtagc tattttaggt gtaggaacga ttgcacaaca accaatcgta
    55921 aatgctgaag gcgaaatcgt tgtcggtcgt gtgatgaaac tgtcattaag tttcgatcac
    55981 cgtatcgtag atggagcaac tgcgcaacaa gcaatgaata atatcaaacg tcttttagct
    56041 gatccagagc tattaatgat ggaaggatga taaacaaatg gtagttggag attttgctgt
    56101 agaattagat acagttgtaa ttggtgcggg acctggtggc tatgtagctg ccatccgcgc
    56161 tgctgaaatg ggacaaaaag tagcaatcat tgaaagagag tatattggcg gtgtttgttt
    56221 gaatgtcggc tgtattcctt caaaagcact gatagctgca ggacaccatt atcaagagtc
    56281 actagattct gaaatgtttg gagtaactag tgaaaacgtc aaactagatt ttgcaaaaac
    56341 acaagaatgg aaagaaaaca aagttgtcca tacgttgact tctggtgttg gtttcctatt
    56401 aaaaaaacat aaggttgaaa caatcgaagg agaagcgttc ttcgtagatg atcacacact
    56461 acgcgtcatt catccagatt cagctcaaac ttattcgttc aataacgcaa tcatcgcaac
    56521 aggttcccgt ccaatcgaga ttccaggatt taaattcgga ggacgtgtgt tagattctac
    56581 tggcggatta gcattgaaag aagtacctaa gaaatttgtg atcatcggtg gcggtgtgat
    56641 tggtgccgaa ttgggcggag cgtacgcaaa cttaggagca gaagtaacga ttcttgaagg
    56701 ctcaccacaa attttaccaa cttacgaaaa agatctagta aaattagtag aagatgattt
    56761 caagaaaaaa ggcgtaacag tcgtaacgaa tgcaatggcg aaagaagcag tcgataacgg
    56821 tgacagcgtg acagtgaaat atgcagtgga cgggaaagaa gaattcgtta ctgctgatta
    56881 tgtgatggtc actgtaggtc gtcgtccgaa tacagatgat atgggcttag aacaagcggg
    56941 tgtcgaagta ggagaacgag gattgatcac ggtggataaa caaggacgta cgaacgtacc
    57001 taacatctat gccatcggtg atatcgttcc aggggcggca ttagcacaca aagccagtta
    57061 tgaagcaaaa atcgctgctg aagcaatctc tggcaaaaaa gtagctgtag attataaagc
    57121 aatgccggca gtagccttca ctgatcctga attggcttct gtaggtatga cgatcaaaga
    57181 agcaaaagat gctggtatcg aagcaaaagc atataaattc ccattttcag ggaacggtcg
    57241 ggcattatcg cttggtaaaa cagaaggatt catccgtcta gttacgacga tcgaagataa
    57301 cgtgcttatt ggcgcgcaaa tcggtggagt cggcgcaagt gatatggtct ctgaattagc
    57361 tttagcaatc gaatcaggaa tgaatgctga agatatcgcc ttgacgattc atcctcatcc
    57421 atctcttggc gaaatcgtca tggatgcttc ggaattagca ttaggtttac caatccatat
    57481 ttgatttgaa taatacaggc gaaacgcaac tgaaaaatca gttgcgtttt gttttttaga
    57541 attatcaata atattattat gtaaacttaa aaatatgaca acttcttggt ttattaccac
    57601 ttcctatgct acactgaaga ggaatatgaa ataggagagt tgaagatgca agaatatcag
    57661 tatccacttg atttagattg gacaacagac gaaatggtca ttgtaatgaa gatgtgggaa
    57721 gatctggaac gtgcgaatga aaaagggata aacaatgaag cttttttgaa gacttatcag
    57781 cagtttaaaa ctgttgtcaa atccattggt gaggaaaaac gattgggacg ggaatttgaa
    57841 aaagcttccg gttattcttt atatcgtaca gtgcagcaag caaaaaaaaa tccaaacaaa
    57901 actttgagaa tgaacgggtg agataaatgg aacagatgat tgatcatatc aagtcctggc
    57961 ttgaagaagc tggtgagaaa atcaaatctt ctcaacaaac attaacaatc tcgcaaaaat
    58021 caaatcgaac ggatctagta acaaatgtcg atcgaaacat ccagaatttt ctaatcgaaa
    58081 aaatccattc ctttgatcca gaggcgaaaa tattggcaga agaagaaggg tgtaatcaat
    58141 tatcggatct cgatggaaga gtctttatca tcgatcctat tgatggcacc ttgaattttg
    58201 tgattgaagg ggaaaatttt tgtattatgc tcgctgttta tgaatccggc gttggaaagc
    58261 ttggtttcat ttatgacgtg atgagaaatg aacttttttg gggtggaaaa ggaataggcg
    58321 tgtataaaaa tgatgagcca ttgcctagac cagcaaataa atccttatcg gaaggcttac
    58381 ttggtgtgaa tagttatctt ttcggtcata ataaatatgg aatccgagaa attgcggaaa
    58441 gcagcatggg gacacgtatg tacggatgcg ctggtcttga actagtggca atcttgaaag
    58501 gaaaccacat tgcttatatt tcaaacctta gcccttggga ttatgcagcg ggaaatgtct
    58561 tattggaaga gtttggtatg gtaacaagcg gtctttttgg tactcctttg acatttgaaa
    58621 aaagggaata ctatttagca gggacttctt gtgcatatgc agaaatcgca gaccttttga
    58681 aaaaagaagg ctgaaaaaaa ggtagaaatc attcacaaaa atgataaaaa cgagcaaaag
    58741 attaattttc tcgaaaaaat gaaaacattt tactatattt catgaaaaaa gtctgctata
    58801 attagcagtc gagtaaaatt tgccctgtca taaagaacca ataaaaaagg agttagttac
    58861 attgaattat agaaacgata tccgtaacgt cgcaattatt gcccacgttg accacggaaa
    58921 aacaacatta gttgatgaac tattaaaaca atcagataca ttagacgcac atacgcaatt
    58981 gcaagaacgt gcgatggact caaatgcgct agaaaaagaa cgtggtatca cgattttagc
    59041 caaaaacaca gctgtagact ataaaggtat tcgcgtaaac atcatggata ctccaggaca
    59101 cgcggacttc ggtggcgaag tagaacggat catgaaaatg gttgacggcg ttgtgttggt
    59161 cgtagatgcg tatgaaggaa caatgcctca aacacgtttt gtattgaaaa aagcactgga
    59221 acaacatatc acaccaatcg ttgtcgtaaa caagattgac aaaccttctg ctcgtcctga
    59281 gcatgtcgta gatgaagttc ttgaactatt catcgaatta ggagcagatg atgatcagtt
    59341 agactttcct gtgatttatg catctgcact aaatggtacg tcaagcttgt cagatgatcc
    59401 agcagatcaa gaaccaacca tggcacctat ttttgataca attattgaaa aaatccctgc
    59461 tcctgtcgat aacagcgacg aaccattaca attccaagtt tcattacttg actacaacga
    59521 ttatgtaggt cgtatcggaa tcggacgtgt atttagagga acaatcaaag taggagacca
    59581 agtagcatta attaaattag acggaacagt taagaaattc cgtgtaacga aattatttgg
    59641 tttctttgga ctaaaacgtc tagagattca agaagcaaaa gctggagact tgattgctgt
    59701 ctcaggtatg gaagatatct ttgtcggtga aacagttact cctgtggatc atcaagatgc
    59761 gttacctatc cttcacattg acgaaccaac attgcaaatg actttcttag ttaataattc
    59821 accatttgcc ggtcgagaag gtaaattcgt aaccgctcgt aagattgaag aacgtttgat
    59881 ggcagaactt caaacagatg tatccttacg agttgaacca acaaactctc cagatgcatg
    59941 gacagtttct ggtcgtggag aattgcattt gtctatcttg attgaaaaca tgcgccgtga
    60001 gggatacgaa ttgcaagtat ctcgtccaga agttattgaa aaagaaatcg acggtgtaaa
    60061 atgcgaaccg tttgaacgcg tgcaaatcga tacaccagaa gaatatatgg gtagtgttat
    60121 cgagtccttg agcttacgta aaggtgaaat gcaagatatg gtccatacag gaaacggaca
    60181 aatccgtttg acattcttaa cacctgcccg cggtttgatt ggttattcaa ctgaattcct
    60241 ttcaatgaca cgtggttacg gaatcatgaa ccatactttt gaccaatatc tgccaatgct
    60301 tcctggtcaa attggcggac gtcaccaagg ggcgcttgtt tcgatcgata caggaaaagc
    60361 aacgacttat tctatcatga gtatcgaaga acgcggtaca gtcttcgtag aaccaggtac
    60421 agaagtatat gaaggaatga ttatcgggga aaacagccgt gataatgatt tgactgtcaa
    60481 catcacgaaa gcaaaacaaa tgacaaacgt acggtctgct actaaagacc aaacatctgt
    60541 catcaaaaaa ccaaaacaat tgacgttgga agaatctttg gaattcttga atgatgatga
    60601 atattgcgaa gtaacaccag aaagcattcg cttgagaaaa caaattttag agaaaaatgc
    60661 tcgtgaaaaa gcatctaaaa agaaaaaata atctgtaaaa ggatgaagag agaaaccagc
    60721 ttgttataaa aaatagctgg tttctttttt tgtccaactc ttttctgtgg agaagtcatc
    60781 tttgtcaatg gacataaatt cagaaaatac gccgaaagac gtttaaaaga cttttaaaaa
    60841 acttatttct agagagtttt tgtttcataa taagataatg tttcacgaaa ggagatcaac
    60901 ttgtccttcg aagaaaatcg aagtaaaatg gcaagagaaa ggagcgggaa gatgaacgac
    60961 ttattaaaac aatactttgg ctatgatgag tttagacctg gtcaaaaaga aattatccag
    61021 aaagtcattg atcaggaaaa tgtattagga atcatgccta ccggaagtgg gaaatcaatc
    61081 tgttaccagc ttccagcttt actattagat gggcttactg tggttgtgtc ccctttaatc
    61141 tctttgatga aggatcaggt ggacgcggcg aatcaattag gtatacccgc cacttttatc
    61201 aatagctcgt tagatggtta cgaaacagct agacgcttcc aagaaatcga tagacagcag
    61261 taccgtttac tttatatcgc tcctgaacgt tttatcatgc cggattttat ccaagcaatg
    61321 aagcgatgga acgtccgtat gatcgctatt gacgaggcac attgtatctc tcagtggggg
    61381 catgatttcc gcccaagtta tttacagatg gcgaaccagc tagatcaact gccaaatcgt
    61441 cctgtaattg ttgctttgac agctacagcg actgtgcaag tagctgctga cataaaaaga
    61501 cttttaaaaa ttccagaaaa caaccatatt cagactggtt ttgaacgaga aaatctacga
    61561 tttcaagtaa ttaaagatca aaaaaaagaa caatatctaa tcgaatattt aaagatcaac
    61621 aaaaatcaat ctggtatcat ttatgcagca acgagaaaag aagtagaccg tctctatcat
    61681 ttgcttaaaa aattcgattt ttccgtgggt agatatcatg gtggtctaaa tgagaatgag
    61741 cgaacagaaa tgcaagaagc ctttttatac gatcgcttgc agctgattgt agcgacaaat
    61801 gcatttggta tgggtagaaa taaaagcaat gtccgttttg ttatccatta tcaaattcct
    61861 ggctctctag aagcatacta tcaggaagct ggtcgggcgg gaagagatgg tctttccagt
    61921 gaagccatcc tgcttttctc tcctcaagat atccaagtcc aaaagttttt tatccagcag
    61981 tcccaaagag aagaagggca aaagcaaaaa gaatatgaaa aattaaaagc gatgacagaa
    62041 tacgtgtata ttgagtcctg tcttcagcaa tacatcctaa actattttgg cgagacaagc
    62101 agtccgtgca accgttgtgg taactgttta gatgacagag aaatagtaga agtaacgaca
    62161 gaagcacaga tggttctttc ttgcttaaaa cgtatgggtg agaactatgg taaacaaatg
    62221 ctgatgaaag tcttagcagg atcgaaagaa caaaagctgc aagctttagg ttttggacat
    62281 ttatctacct atggactgat gaaaaaccaa tcgcaaaaag aaacgatgca gttaattgaa
    62341 tatttgatat cgaatggcta tcttctgacc atcaatggtg agtatcctgt tttgaaagta
    62401 acagaaagag ggatacaagt attgaaagga caagaatctg tttatcgaaa ggaacccaag
    62461 aaagtccagc agctatcgga tgaagaaacc gatacactat ttgaagtgct gcgggaactg
    62521 cgaacggatc tagcatcaga agcaggcgtt cccccgtatg tcgtattttc agattccaca
    62581 ttgaaagaaa tgagccgaat acgtccatca agcagattgg agatgcttca gataaaagga
    62641 gttggccaaa gcaagcttga taaatatggc gaagcctttt tatctcggat aaaaaatgcg
    62701 gactctaacg ttctggataa gtagaaagaa cgaatacgta aaaatgaata aaaacaactg
    62761 gttaaatctg ttttttttgc tccttatgaa aatcaaatat gttataatta aggaattaga
    62821 atgggaggta agcacagatg gattctttgt cgaaaaaact tgcgatccaa gtattaaatg
    62881 atgaagcaga acggatcaaa cgattaatcc gaaatcaaaa caacagtctc tgtatctcac
    62941 aatgcaaagc cttcgaagaa gtggtagata cacagatgta cggcttttcc cggcaagtcg
    63001 gttttgctgt ccgtatagga gtaatcggaa agaacgaggg ccagctgatg ttaagtgagc
    63061 tagaacgaga attgaatcag ttatatagtg aggtttacca agaaatttat gataaaaaag
    63121 aagttggcaa ggaggaatag acttgcctaa gaaagtgaaa aaaaggcatc tattagacta
    63181 tagcatcttg attccctatt taattttatg tgtattggga ttgatcatgg tatatagttc
    63241 tacgtcgtat ctattattag aaaacggaca aaatccgtcc gcatcagtca ttaaccagag
    63301 tattttttgg gtgcttagct tgattgctat cgcactactt tataaaatga aaacagatgt
    63361 tttgaaaaac cagcgtttga tcatggcagc catcgcagtt ttgacgattt tgctgctgat
    63421 tgttgtgttt tttggtaagg agatcaatgg ggcgaaaggt tggctgcaaa ttgcaggatt
    63481 ctcgatccaa cctgccgaat acctaaaaat catttctatc tggtacctgt ctctgacttt
    63541 atctaaaaga caaaacagtg tacaaaaaga ttttcttggg actgtgaaac gtccacttgc
    63601 aatggttatc ggacttactg cattagtcgc tattcttccc gattttggta atgcggcagt
    63661 tatctttttg attattttgg ttctgctttt agccagcgga gtcaattatg tgtatacttt
    63721 gattgtagga gtaggaggct tttgtctaag tacttttacg atctggctga tcaatatcac
    63781 aaacggaaag atcttacccg gacgtttaca gtatatctat aatcgatttg ctatttacca
    63841 aaatcctttc tcagacgaat taaataaagg gcatcaacta gtcaacggct actatgccat
    63901 gttcaacgga ggactatttg gcaggggatt aggtaacagt atccagaaaa aaggattttt
    63961 acaagaagca caaaccgatt ttatttatgc aatcgtagtg gaagaactgg gagtgattat
    64021 ggggattttg atattagcgt tgctattctt tatgattgtg cgcattgtcc ttgtaggtat
    64081 ccgttcaaaa gatccgttca attcgctttt gtgcattggg atcggcgcaa tgtttttgat
    64141 ccaagtattt gtcaatcttg gaggaattac tggcgttatt cctttgacag ggatcacgtt
    64201 cccattttta agtcaaggag gctccagttt gctgatgctt tcgatttgtg tcggctttgt
    64261 cctcaacatc agtgcggatg aaaaacgcaa gagcttaggt ttataataaa aaaagatgta
    64321 ggagtggttc gatgaaaaaa gttttagttg ctaacagggg tgaaatcgct gtacgtgtat
    64381 ttcgtgcttg tacagaatta ggaattaaaa ctgttggaat ctatgcagaa gaagatgaat
    64441 attccgtaca ccgtttcaaa gcggatgaag catatttagt aggacaagga aaaaaaccga
    64501 ttgatgcgta tctagatatt gaagggatca tttctatcgc gaaagaatgc ggagctgacg
    64561 ctattcatcc gggttacggt cttttgtcgg aaaacttgaa ttttgcgcaa cggtgcgaag
    64621 aagaaggcat catttttgtt ggacccaaac tgcatcattt agatattttt ggagataaaa
    64681 tcaaagcaaa agctgcagct atcgaagcgg ggattgcttc gattccaggc acagatggac
    64741 caatcgcttc tatagacgat gccttggagt ttgcgaaaca atacggttat ccgattatga
    64801 tcaaggcagc tctaggcggc ggcggacgcg gcatgcgtgt agctcacgat gaaaagagtg
    64861 caagagaggg ctacgaacgt gcgaaaagcg aagcaaaagc agcctttggt agtgatgaag
    64921 tgtatgttga aaaatacatc gctaatccta agcatatcga agtacagatt ctcggggata
    64981 cgcatggaaa cgtcatccat ctttttgaaa gagattgttc tgttcagcgc cgtcaccaaa
    65041 aagtagtaga agtagcgcct tgtgtctcta tgaatgaaca gcaacgtcaa aaaatctgcc
    65101 aggcagctgt ccaattgatg aaatatgtcg ggtatgtcaa cgcaggtaca gtagaatttc
    65161 ttgttgaagg agatgatttt tactttatcg aagtcaaccc tcgcgtccaa gtggaacata
    65221 cgatcacaga aatgattaca gatattgata tcgtaacaac gcaactgttg attgctcaag
    65281 gtttggatct gcataaagaa atcggattgc ctcagcaaga aggaattaaa ttaaatggtt
    65341 cagccattca atgccgaatc actacagaag acccgttgaa taacttttta ccagacacag
    65401 ggaaaatcga tacgtatcgt tcacctggtg gttttggcgt acgtctggat gtcggaaatg
    65461 cttacgcggg ctatgtagtg acaccgtatt ttgattcatt gctagtaaaa gtatgtacgc
    65521 atggtgctac ctttgaaaca gccattcaga aaatggaacg ttgcttgaaa gaatttagaa
    65581 tccgtggagt gaaaacaaac attccattta tgctcaatgt catcacacat cctgaattcc
    65641 aatcaggaaa tgcaaaaaca accttcattg atagtacagc aacattattt gaatttcctc
    65701 gactacgaga ccgcggaaac aaaacgatga aatatatcgg tgaaattact gtgaatggtt
    65761 ttccaggtat cgaaagtggc gaaaaaccat tttatgaaga accacgtatg cctaaagatc
    65821 taatcacaag aactgattac gtaacggcta agaatgtatt agatgcgaag ggtgccgatg
    65881 ctttggtcga atggatcaaa ggacaggaaa atttgttgtt gacggatacg acatttagag
    65941 acgcccatca aagtctgcta gcaactcgtg ttcggacaaa ggatttcaag cagattgcac
    66001 gtttgactgg agaaggtctt cctgaactct tttcaagtga gatgtggggg ggagcaacat
    66061 ttgatgtggc ttaccgcttt ttgaatgaag atccttggca acggttgaga aaaattcgtt
    66121 ctttaatgcc taatacgttg ctgcaaatgc ttttcagagg ttcaaatgcc gttgggtatt
    66181 ctaattatcc tgacaatgta ttggtggaat ttgtcaaaga agcagcagcg caaggaatcg
    66241 atgtatttcg aatctttgat agtttgaact ggactccaca aatggaaaaa agtatccaag
    66301 ctgtacggga tactggtaaa atcgcagagg cagctatttg ctatactggc gatatcaacg
    66361 atccaagtcg ggcaaaatac aatgttcagt attataaaga catggcaaag gaactagaac
    66421 aactgggtgc gcatatcatt gcaatcaaag atatggctgg gctgcttaaa ccgcaggcag
    66481 cttatcgttt gattagtgaa ttgaaagaaa cgacagatct gccaatccat ctgcatactc
    66541 atgataccag cgggaatgga atcatcactt attctgctgc ttcaaaagca ggagtagaca
    66601 tcgttgacgt ggcaatgagt gcaatgagtg ggaatactag tcagcctagc atgagcagct
    66661 tgtattatgc actggtcaat ggtccacggc tgccagaaat cacgattgaa aatgcacaga
    66721 aattaaacca ttattgggaa gatgtgcgca tgtattacaa accgtttgaa aacggcttga
    66781 atgctcctga aacagaagta tatatgcatg aaatgccagg aggacagtat tcgaatctac
    66841 agcaacaggc aaaagctgtc ggattaggtc atcgctggga tgaaatcaaa caaatgtatc
    66901 atactgtcaa cttgatgttt ggcgatatcg ttaaagtaac tccatcatct aaagtagttg
    66961 gagatatggc actatttatg gtccaaaatg atcttacaga agaagatatt tatgaaaaag
    67021 gcgaaacact aagtttccct gaatctgttg tgactttctt ccaaggagaa ctagggcaac
    67081 ccgttggcgg atttcctaaa aaattgcaaa agattattct taaaggcaga cctgcattga
    67141 atgaacgtcc aggtcttttg gctgaatcag tcgacttcaa cgaagtaaaa aaagaattgg
    67201 cagaaaaaat tggctatgaa ccaaaacaag acgaagtatt aagctatttg atgtatccgc
    67261 aagtcttttt ggactatcaa aaagcatata atcaatttgg cgatgttaca ttactggaca
    67321 caccaacatt tttccaaggt atacgtttgg gtgaaacaat caatgtacaa atcgaacgcg
    67381 gaaaaacgct tatcattcgt ttagatgaaa tcggagaacc cgatatcgaa gggaatcgcg
    67441 tactgttctt caatttgaat ggacaaagac gtgaaatcac tatcaaagat aattcgatca
    67501 tcagtacggt ccaaacccga ttgaaagctg aaccgacaaa ccgagaacaa attggagcaa
    67561 cgatgtctgg ttctgttttg gatgtattag tgaaaaaagg cgataacgtt aaaaaaggtg
    67621 atacgttgat gattactgaa gcgatgaaaa tggaaacggc catcgaagca cgttttgacg
    67681 gagaagtcgc acatgtatat gtgtcttcag gagacactat ttcgtctggt gaccttttga
    67741 ttgaagtgac tgagaaataa taagcgaaag gtggggaaac atgaaaagac tgggtttgtt
    67801 ttggctgatt ctgctattag ttattgtggc attctacatg gaaccagtct tgtttccgcc
    67861 aaaacttgaa gtgaaggaaa actctgatca acaaatatca aaccaaatga caacgtggaa
    67921 ataccaggag cttaaagcaa ctggtttttc tacttatatc ggaaaaccga tcgatcagct
    67981 ggaaaaggat tttggccaag cctatgatcg attaactagc ggatttggtt ttgaaacaag
    68041 atattatgaa aataaagcta gtcatctcac atttgaagcg aacatccaag acagcagagt
    68101 cacaactgtt aaagtactgc aaacagggcc tgctgatatc gcgccgtttt atttagggat
    68161 gacgatgcaa gatcttacga aaatcactac tatctatact aatttcactt ttgagtacca
    68221 tgatacagaa gttggaatcg aactaatgga agaggatatg aattatcgtc cgctaattgc
    68281 ttttgataac gacacttttg ctattttatt ttttgatcaa acaacaaacg gcctattttc
    68341 agttgtgtat ttagataaag atagtctttt gaaactattg ccatatcaag tgtttggtga
    68401 aggccttcca cattatcaag cagataaatc ggctgattgg gaatcaatca atcgcgttaa
    68461 agaacgaaaa agtacgactt tattaaatat gcttagaaga gaagacgaac ttcccatata
    68521 caatcaaaca cttgcctttc aaaaccacag tcagctgcta ctacatgatt ttttgacaag
    68581 gcctgaggaa atattgtcag aggaacgtat ggctgattgg caaaaatcgc taggcagtgc
    68641 tcaaacgaca gtgaaattct cactgacgaa tgatgaattg gagaagttaa tcagtaaaca
    68701 aaaattagaa aatactagtg ggctatttat tcatccggcg attgacgcta ctttttcgtt
    68761 tttatattgg tacagcgatc cttacaacca tgaccgtttc atggacccgg gaacggattc
    68821 tgtaggcatt gctttttcta aagaaaatat gttagtctta ttgcaagaag aaaacggaga
    68881 aagtagtgat agcagtgatc gttaacgaag agctgtttca actggaggat caatgcctcc
    68941 aagtcgctga aatgataaaa aagagtaaaa cgatggcttc ttatcttgaa cataaacagt
    69001 caatggaaga atctgcaaaa gtttgccagt tgaaagaagc gttcttgtct aagaaagaag
    69061 catttgaaaa tgtagcggca tatggtgagt atgcacctga ttatcgtgaa aaaaaacgag
    69121 ctgttcgaaa agcaaaaaga cagcttgata tggatgagca tgttgcagct ttccgatata
    69181 gtgaaacaca gctgcaaagt ctgttggatc aaattgtcca agtacttgcc gaagaagttt
    69241 ctaatgaaat caaagtagat gcaggtagcc cgttttttga aacgaaaaaa cactttggat
    69301 gcggaggtaa ttgtcatgca attagacaat agtgaatttg aaataacaaa acgacgcggg
    69361 ctgatcgtat gggtctacag cttaaaacaa ttaaagaatc tgaaaaagtt cggcttgttg
    69421 cattatgtct caagaagaat gaaatatgtc gtgctttact taaatgaaga gacattggaa
    69481 gaaacagaag aacgaatccg taaattacat tttgttcgaa acgtagaacg ttcttaccga
    69541 ccggatatcg aaatgaattt tgccgaaaaa ataggaaaca aaacagtatt aaaagacgaa
    69601 ggtttcgaaa ttgaagagct aaatacagaa atccgattag ctgaacatct ttaaaaatct
    69661 cttatgagca gtttttaaat aaaaaataac ttggataacg atcgattttt gatcattgtc
    69721 caagtatttt tttggtatac tagtaccagt accatttcta aggagtgagt agatgcggat
    69781 aatatcagga aattatggcg ggcgccgttt aaaaagttta gcaggggcga acaccagacc
    69841 aactacagat aaagtaaaag aatccatatt caatatgatt ggaccatatt ttgatggaga
    69901 gacagtattg gatctgtttg caggaagcgg tggtttagct atcgaagcag tatctagagg
    69961 ctgcagtcat gcggtatgcg tagacaaaaa ttaccaagcg ctaaaaatca tcaaagaaaa
    70021 catcgaaatt acgaaagaac cagagaaatt taccacaata aaacttgatg cggacaaagc
    70081 aatcgaacgg ctagcagcgg agaaacaaca attcgactac ttgtttcttg atccgccata
    70141 tgcaaaacaa aaaataatcg atcaaatcca taaaatggaa gaactgggac ttttttctaa
    70201 aaccgcagtt atcgtatgcg aaacggataa aacagtcgaa ttgccagaaa ctgtggctgg
    70261 attccatcaa ataagaaaac agatttatgg cataacggcc gtaactatct atagaaaaga
    70321 gggaaatcaa tgaaacgtgc attattccca ggaagttttg atccttttac aaaaggtcac
    70381 ttagatacgg tggaacgtgc ggctaaatta ttcgatgagg tagtaattgg tgtttttatc
    70441 aatacttcaa agaaaagttt gtttccccca gaagaaagaa tgacattgat cacaaaagct
    70501 gtttctcatc ttcctaatgt aaaagtcatg catcaagaaa atcaattgac ggtagaaaca
    70561 gcaaaagaga ttggtgcaga tgcgttgatc agaggcatac gaagtatcaa agactttgaa
    70621 tatgaacgag agattgctca gatgaatcat catctatatg atgaattgga aactgtcttc
    70681 ttattagcaa aaccagaata tagtcacgtg agttccagta ttttaaaaga agtactgcac
    70741 tttggcggag atgtgagcag ctacttaccg ccagtgatca acgaagcttt agctggaaag
    70801 cgtgaatcaa atgaaagcta aacaatggtt gaaaacagta ctgattatca tatttggaat
    70861 gttgatcatt ggatttgtag tagttccctt gccgtattat gtagaatcac cgggagccac
    70921 gatcgatctg aaagaactaa ttacggtcaa tgataaggaa gataaaggtt ctgggtcttt
    70981 ctctcttacc tctgttggta tcaggcaagc tacaggtttc ttagctttaa aagctaaaat
    71041 gacccctttt gaagaattga tcagtgaaga agaattgact ggtggggcga caaatgaaga
    71101 atataatcaa atgcaacagt attatatgga ttcttcccaa aatgcagcaa tcgaacaagc
    71161 gttaaaactt gcagacaagc cttataaaat ggaattcaaa ggcgtatatg tcatgagtgt
    71221 agagaaaaca tcgaatttct ttggcaagct ttcagttgga gatacagtaa caaaagtaga
    71281 cgggaaaagc tttcaaagta cagaagcatt tatggattat gtaaaaagcc aaaaagttgg
    71341 acaaacaatc gaaatcagtt atttgcataa tggtgaagaa aaaacagctt ctggtgatct
    71401 gatcgagtta ccaacagata aaaaggcagg aataggtatc acgcttactg accataccga
    71461 gatcgaatca gatacagatg ttcgtattaa ttctggctct atcggtgggc catcagcggg
    71521 attgatgttc actttagaaa tctatgaaca agtcactggt aaaaacttgc gacatggtaa
    71581 gcaaattgca ggaactggaa cgatcaacag tgaaggagaa gttggccgaa tcggaggaat
    71641 cgataaaaaa gtggcaagtg cggataaagc tggcgtagag attttctttg caccagatga
    71701 tacgatttca gacgatgtta agaaagaata tcctgaaata aaaaccaact acgaagaagc
    71761 aaaagctgcc gctaaaaaat tgaattcctc aatgaaaatc gtaccagtaa aaacagtaca
    71821 agaagcgctt gactatctag agaaaatgaa atgaaactaa ataattaaag aggggttgtg
    71881 acacgagttc tgtcacaacc cctctttttc gtcaaaaatc ttcacgataa aaataaaaac
    71941 aaaagaaaaa attgacgtaa ttagatgttg aagggacgat tttgccagag ctcactgttt
    72001 cttcaatttt aaatgaaagg agtaatgaat gatttttact ggtcattctt tgaaaaaaga
    72061 acaatgatag aaaaaatcag caagaaaata ctagcttcac ccaaattgat catttggatg
    72121 tctatgatag ttcttatctt ttgtatcgca agtggttttt tattatcaaa tttgctattt
    72181 tatagagaaa cagaagagac tgctgcaaaa gaaatacttt cttcgtttag ttccagtgga
    72241 gaagatccat cagctgaagg aaacgatgta gaagaggatg ctcgtccaaa ggtcatgtac
    72301 accgatatca aaggaagtgt gaaggagcct ggtatctatt ccttttcttc agaagaacgg
    72361 gtctatgatg tactaaagcg tgcaggtgga ttattagaag aagcggatag cgatcgaatc
    72421 aacttttctg cgaagataga agatcagcaa gtcctatata tccctgctgt aggtgaagag
    72481 ctgccagaac atcttgatca gttggcatcc tcggaaggaa aacagcctac agcagattcc
    72541 gagcctccca aaataaatat caatacagcc actccatcag aacttcagca gattcctggg
    72601 atcggatcag tcaaagcgca agaaatcatt cgatttagag aagaaaacgg atccttccag
    72661 aaagtggaag acctgcagga gatttctggt atcggtgaaa agacagttga aaaactaaaa
    72721 aacttcgtta caattaaata gaatgattca aaatcgactg gcacgagcaa taaatggacg
    72781 ctaatggata ctaagaataa tccaattcta agagcttggc aggacgagga ggtagtattt
    72841 ttggatagga aatagcttga ttgttcgcaa agaaacatta aaaaaaccaa tgctgaatgt
    72901 ctatctccaa aataaaatat ctgggattca tattatgaat acggctgtca gcggcaataa
    72961 cagtcaagct ctacgagaac gctttgccaa agatgtactt agctatacag cagataaagt
    73021 atttattctc attgggacga atgatctagc agagcataaa caactttcta aagaaacgta
    73081 ccaaaaaatc tgcagtggat gatagttcag ctgaaaaaag actatagttc tgatcatgct
    73141 ttctttatca cgccaccagc agtcgatgag acaaaacaaa aatatcggaa taacaagttg
    73201 atcaaagaat atatctctgt tctcacagaa gtagcaaaac gccatgattg tgaagtatcg
    73261 atttttatac ggaatttctt gaacaaatgg attcgaagaa tttttataat gggctaatgg
    73321 atgacggact tcatttcggc agtgaagggt aggatctttt gtcagacagg atgattcgtt
    73381 atatttaaag aatattttgt ttaagcaatg agtacttttt aatcaacttg aaaaaacgga
    73441 ggaatataaa acatgttaga aaaatcttca aaagcatgcg atacgaataa agaaaaagtt
    73501 actgataagt cacataatga acgcattcct tgggaccagt actttatggc tcaggcagta
    73561 ctgttatctt tacgtagtac gtgtacacgt ttagaagtag gagcgacact cgttcgagaa
    73621 aaaaggatca ttgctggcgg ctataatgga gcagtcagtg gagatgtcca ctgcatagat
    73681 gaagggtgtt acgtcgtgga tggacactgc ttgcgaacga tccatgcaga gatgaatgca
    73741 ctcctacagt gtgcaaaact tggtatcccg acggaaggtt cagaaatcta tgtcacacat
    73801 tttccatgtt tggcctgtac aaaggctttg ttgcaagctg gtgtgaaagg gatcaattat
    73861 ctccatgact atcgaaatga tccttatgcc caagcgttga tcgaacaatt aggtgtatct
    73921 gtacaccaag ttgctttaga ctcacagcat ttttcaaaac ttcaaaatga attaacagga
    73981 aaacatgtct agcgttttag aaaggcatgt tcgaaatcgg ttgatttttc cggcaattac
    74041 gtcgatgatt atctgtttgt tgtattacac tgacaattgg ggttatcgtt tgcttcttgc
    74101 cggaattttt ttatggtttt cgctaaaaga aggacgtttt atcgcgtact tgtgtatttt
    74161 gtgtagcata acggtatcca tttcttatag gctacaagag tattcatttt tagaggaaaa
    74221 aacaacatct gcgcaaatta ctgtatttac agatacgatt cgtgcaaatg gtaatttttt
    74281 gacaatggaa ggaaggttat cagagaataa acaaaagctc cagctttctt atcaagtaaa
    74341 cacagaagca gaattgaaaa catggcttaa cttccgagga aagggaatag aattgactgc
    74401 tgaaggcgag ttcatctctc cagcaaaaaa gcggaatctt tataattttg accaagaagc
    74461 ttacttcagg aaccatagaa tttctggacg gttccaaatt caaaagattg aacagatcac
    74521 catgcaaaat cactggcgaa actggcttca gagaaaaaga ggatctttta tctcctttgt
    74581 ccaatctgaa tttccgcaaa aaacaagtgt atatattaat tctttattat ggggctataa
    74641 agatgcagga ttcagagaac cagaagaaat ttttagggag agtggtttgc tgcatctgtt
    74701 cagtctatcg ggtctacaca tccaatttta tttagggtgg ctgtattatt tatttcgacg
    74761 tatcggatgg ccactacacg tcagtattat tccgttgagt ctactaacta tctgttatgt
    74821 ttctattgca ggaagttcta tttctgtttt gcgtgctagt ttgctgtttt tattgcgatt
    74881 gctagtcaaa ttgctgaata agcattattc caccatggac ttatttgcag ttgtcttttg
    74941 gcttctttta ctatttgatc ctcgatttct ttttcatgcg ggtggacagc ttagtttttt
    75001 catgagtttt ttgtttatcc tgatttcttt tgatggagat tggttgaaaa aaacggcctc
    75061 tcacgtcctg tttactatga tcacgatgcc gttgattgta tggcattttt atgagtggcc
    75121 tattttaggt agtcttttta cattactgat tgcaccggta ttcaagtttc tttttcttcc
    75181 tggtgtgtta tttctcacac tcttcaatcg ctggctgccg gaaactttac ttttgttgat
    75241 agaagaggga ttaatcttat ttgagcgaat aatcgatttt tcttcagggt cgtctctcat
    75301 tataggacgt ttgccccttg tgctatctgg gatgtatatt ttcggattac tgatttgtat
    75361 ggataggttg aaagaacaac ctgtgaaaca cttgttttat gttggtcttt tttcttttat
    75421 ttttttgact ttgccatttt tacgcttttc ttcaacgatc gcttttatcg atgtcggtca
    75481 aggagacagt atctttttgc aaagtccttt tcgaaaagaa acgattttga tcgatactgg
    75541 aggtcagtta cactttgaaa gagaaaagtg ggcgcaaggt atgatacgtc ctcctgctga
    75601 aagaaatatc gttccatatc taaaaggtca ggggataagt gtaatcgata aactcatctt
    75661 gacacacgac gatacggatc atgtgggaga attacccacg ttatctcagc attttactat
    75721 caaaaaaatt tatatcggtt ggggcgctgg acgaaatgag ccattacaaa ggcatttatc
    75781 tgaagctcaa aaaaatggta ctgagatcat tgaaatcaaa catggggaca ggatcagcgg
    75841 ttattatgat ctttatgtat tgactccttt tgaaaaggga gagggaagaa atgaagattc
    75901 gattggtcta tggatggaat ataacaatag gcgcttttta tttttaggag atttgaatca
    75961 agcaatggaa aaacaattgc ttttgattta tcctaatctg aaagccgatg tagtcaaatt
    76021 aggtcatcac ggtagccgta cgtcaagtaa cacagatttt ctttcccata ttgaagcaaa
    76081 acatgggatt atatcctgcg gcgtaaataa tcgttatggt cacccgcaca gcgaagtatt
    76141 ggagacacta gaagaaaatc agataaaaac atggcgaacg gatcaacaag gaatgatcac
    76201 ctatcgctgg catccagttt ttcatcctca tgggctagtg ggaacaatga tagactagta
    76261 attctcatct gctcatggta ggataatttt tgaaagtggt gagtaatttg agtatacaag
    76321 cagagttaca aaaaatacgt aaagaaaaac ttgcatcttg ttacttgatt ttaggaacag
    76381 aaaagtttct ccaagatcaa gttcggacag aaattgtcaa aaaaatccaa ttagagggcg
    76441 aagatgactt aaatttttta agttttgaca tggaaaatgc aagtttagat gaggtagtag
    76501 ctgaagcaga gacgttgccg tttttcggag atcaacggtt agtattcgta gagaatcctt
    76561 attttttaac aggtgaaaaa gtaaacaatg gaatcgaaca aaatactgat ttattgacgg
    76621 cttatttgaa agaaccatta gaatcgactg tattagtatt ctttgcgcca tatgaaaagt
    76681 tggatgaacg gaaaaaagta acgaaacaat tgaaaaaaac agcaattatc atcaatgtcc
    76741 aacagttgaa tgaaaaagaa gtacgtcaat atctgatgaa taccttagag aattcctcaa
    76801 tcaaaatgga acgaagtgca attgatttat tcttgaggtt gaccgactta gatttatcca
    76861 aaatgatgag agagttacag aaattggtcc tttatggaca aaatcaacag caaatcacgg
    76921 taagagaagt agaagaatta gttcctaaaa cgttagaaca taatattttt gacatgaccc
    76981 aatatatttt aaaagggaag acggaacaag ctttgcgttt atacgaagat ttagttatgc
    77041 aaggggaaga aacaatcaaa attaatgcga ttttgctttc tcaattacgt ttatttttac
    77101 agacaaaatt tcttgtaaag attggttatc agcaggcaaa tattgctgaa acattgaaaa
    77161 tccatccata tcgtgtaaaa cttgccatgc aggaagtaaa aaaattcgat gaacatttgc
    77221 tggtacagtt gtttgatcaa ttagttgaga tggattatca aatcaaaacg ggacaaatcg
    77281 aaaaagaatt aagttttcaa ctattcgttt tgcgcacagg gcagttgtta agaaatcgat
    77341 aagaagaaag acgagggcaa agcatgcggg aaggtcgttt gtttttgtcc tttttttgac
    77401 aaataaaaaa atcggccgaa gccgattctt ttatttagcg atttttttgc ttaaacgaga
    77461 tttgtcgcgg ttagctttgt ttttgtggat tagacctttt gattcagcca tatcaatagc
    77521 tttaacagct tctttatata acgcatctac gttgtcagca cctgaagcta cagcatcttc
    77581 aaattttttg attgcagtac gcatagcgct tgtttgagat gaatttttca cattagcgtt
    77641 ttcgcttgta cgaacacgtt tgattgcaga ttcaatgttt ggcattagtt tcacctccga
    77701 taacttaagt tcttacgcgt gttaccgcat aattcaacat tcattattat acctaaaggc
    77761 agcgtgcttt gcaatatgaa catgacaagt ttttttcctt aacagtcttt tattaggatt
    77821 ttttttcagt aaaaacggat agtacaagct gaaaaaaatc aaaaagacgc tattgtggga
    77881 ggcaatagcg tcaaaccaaa ctagattttt atttatctat ttaaacaaag tttgaatggg
    77941 aatgtttggt actaagttat tatataacaa agagaaccgt ttgcaaagtt ttttttgaaa
    78001 agggatacga ttccctgttg ttctttgttt ttctattaag aaactgcagt tattttataa
    78061 ccagtatcct ttgatcagta aaggctattc tggtgtaccg attattttaa tgtattcatc
    78121 gatatttttt atcaacattt tttttatgac caactggttc cgacggttcc atttgccact
    78181 tacttccagc acatatttat ttaggggcaa acgtaagata tattttgcca aatagcgatc
    78241 tttaagcagg ccattgatca cacggtcctc aagctgcaag ttgatcccag tcagcatcat
    78301 tggctgttct tgtaaaacgt acgtatcaat taaaagacct tcaaaagttt ccacaagcgt
    78361 cttcctttct tttcaaagta acctgaaaac aggcactaat tcttccattt tgatattcgt
    78421 tgaagtggat gcgatcattc tttcttttgt ccactgtaat ctagtataac aaaaaagagc
    78481 agaagagcca aaaagaaaaa agagcatcga attctatagg aagtctcatt ggcacggcct
    78541 aaattattac aaaacattga ttaaaaaaag cccctgcatc gcaggagcat cccctatatc
    78601 gttttaatag gtcaatcaaa aagcagtatc aaacacattt tgtatcaaat caggaaataa
    78661 tagataagct aagcccagaa tcaaaagtac cgctagaaga aaccagccga ttgttcctat
    78721 gaaatacttt aatttttcga acattgtatc acctcgttgt cagtatatca cggatcagta
    78781 aattgggggt gttaagaatc tcctaaaata gacaaaattt gttctatttt cctaaagcaa
    78841 atacttgtaa gatacagtaa gtgataccag aagcaatgac cggtccggcg gcgattcctc
    78901 ttaagaagac aacacctaaa atcgtgccga aaacaagtgc aacagtgatt tgtggatcag
    78961 aagcaatcaa tcctacaccc ttggaagata agacagccac tagcccaccg caaaaaacag
    79021 ctacccagcc aataggggat ttaaaggctt ctaatagatc acgtagaccg atttctcctg
    79081 ttgcgatagg gattagaata gccgctgtga tgatcgtcac cccaatattg attcctttgc
    79141 cttgaagcca agggaaaaag gaacgggagg ctggtatgag cttcataatc aaaacaaaag
    79201 ctgccgctat catcagactt tgatttttag ctaaaattgc tacaagtaaa ataattccta
    79261 aaaaaagcca actttccatg aaatatattc ctcactttct tcgaaacaat cataacatgt
    79321 ttttagaaag ttacaaaagt aggaattcat ccttcaagac ctattcataa gctgtttttt
    79381 tcataaaata aacaaaatca taaaaaaaca ctttgcttat ttgacagaag acagccgcgc
    79441 tttgtatagt ggacaagact tacatttttt tgaagaatca gaaagatcag gtaaaggtct
    79501 tagtaaacgc aagccattca gaataaccaa tattgtgctt ccttcgtgtc ctacaactcc
    79561 aagaggtaga tttaaaaatt gcaggaagtt agaagcaatc aacaagagaa taacaagaat
    79621 cgaaaaaata atattttgtt tgatgatccg ccgcattttt aaagatagcc gatgactgta
    79681 gacaaattta tttaagtcgc ttttcattaa gacgatgtct gcgatatcca tagcggcatc
    79741 tgtcccttgc cccatagcga cacctaaaga agcggctgct aaagcaggcg catcattgac
    79801 tccatcacca accatcgcat ttacttggta aagttcattc tcttttttga ctagttgtgt
    79861 tttttcttcc ggagtacagc ttgcatagta atgttcaatc cctacttgtt cagcaatggc
    79921 ctttgctgtg ccagaatggt cgccggttat catacttgta tggatgtttt gggatttaaa
    79981 gtaggaaatt acttgttggg tatttgcttt tggaatatct agcagaccta aaacagcaat
    80041 taactgctga tctttagaaa gataaatcac ggttttgcct tgattttcca aacgttcgat
    80101 catttccgca atctctttgc tgattatcat cgtctcagga tcatatgcgt gcttgccaac
    80161 tttccattgc gcacctaaat aggtagtttg taatccaaaa ccagtaattt cttctattgg
    80221 taagtattgg atttcttcag gtattgtgca atcgaaatat tgcaaaatcg catgagcaag
    80281 tggatgcgtc gttttttgtt ccatagcaac aagaagttgt tgtgccaaat ccttttcatc
    80341 aaagaaaaag ctgtcagtta caactggttt tcctttagtg agcgttcctg ttttatcaaa
    80401 ggcaatcgct tttaattcag aaagcttttc taaatggata ccgcctttga ttaaaatccc
    80461 attttttgca gaatttgaaa gagcagctag agaagctggt gtagcagatg cgacaagcgc
    80521 acaaggagaa gccacaacta ataataccat tcctcgataa aagctttcat cccaactcca
    80581 acctaggaaa aagtggggga gaaggatcat tagaggaaca gcaagcaaaa tcaattttac
    80641 ataattattt tcgattcgtt cgataaatga agctgtttga gttggcgtat tctgcgcttc
    80701 ttctactaat tggataatct tagcaaagac agtttcggaa ctcgtttttg ttactcgaat
    80761 cgtgatggga tttccttgat tcagcgttcc tgcatacatc tcatcgccta aatatttttc
    80821 tacaggcaca gattcaccgc ttaatgcaga ctcatcgatc gttgcctgtg tgctttctaa
    80881 aaagccatct atcggaacag ctgctccttt agcgacaaat accaagttat ccacctttag
    80941 ttgagaaaca tctacttctt gcatttgtcc attttctttt aataattggg ctttttgtgg
    81001 ttgaagattc atcaaagcag taatttcttt ttgactttta ttagttgtgt attcctctaa
    81061 tgcaccgctt aaacaaaaga tgaatgtcaa cattgctcct tcaaagtaat taccgatcaa
    81121 acaggcacca atagcagcta aagccatcaa taaatccaca ttcagtgtcc gatcattcca
    81181 caattctttc aagccttccg atgtttgttt atatccaccg atgataatgg cactgatata
    81241 aaaaagtggg gtgatggtaa gagagaatcg gtcgaagata aaaccgaaga tcataaataa
    81301 aaggcagccg attgttgctg caaaagcttt tttctgatta gtcatcgtta ttagacctcc
    81361 ttgtcaaaac aaggatagca taataaaaat gtaattgata ataataacag ctaaatgaga
    81421 acgataatgg ttatcatttg gtgattaagc ttgatgttgt ttttattatt tataatgatt
    81481 attattaaag aaaataaaaa accagaacat ttctcaaata agagaagtgt tctggttttt
    81541 tctacattgc aataaaccaa taaccaatca aaatgatacc aaggataata cgataccagc
    81601 caaaagcggt aaagtcgttt ttcttcaaat agcttagtaa gaatttgata gctaagacgg
    81661 aaaccacaaa agatacgaat gttcctacaa gaagaacaac agtttcttcc attttgaatg
    81721 aattcccttc agctaaatat ttgacgatct tcaagccgct tgcgccaaac atgacaggaa
    81781 tccctaagaa aaatgaaaac tctgtagcga caaaacgcga agcaccaatc aagatagatc
    81841 ctaggatcgt tgcgccagaa cgggatgttc cgggaacaag tgccaagact tggaataacc
    81901 caacaagaag agctgcttgg tacgtaaagt cattcagaga agtccaacga ggtgttttgt
    81961 ttttgttgcg tttttcgaca ataataaagg caataccgta aacgatcaaa acaatggcaa
    82021 ctggtaagaa cttgtggaaa tttgcttcta accaatcatc caaaggcaaa ccaatgatga
    82081 tggctggtat gcaagcaacg atcactttaa accaaagtgt ccacgtatct tttttttcta
    82141 ccgttgattt acttggagaa aatgggttta acttgtgaaa ataaagaacg acgacagcca
    82201 agatcgcccc taattggata acgacattga acatcgacat aaattgtgaa ctggcatcca
    82261 gtttgatgaa ttcatctgct aggatcaaat gaccagtact actgatgggc agccattccg
    82321 ttattccttc aataataccg agaatcactg ctttgataat atttgcaaaa aacataaatt
    82381 ccttccttcc caattaagat acatcttata gtataccgtt attttttgag aaacccaatc
    82441 tgttttttaa tattaagaaa aacttgagaa ataaagcaga taagtacacg aagagaaaaa
    82501 agaagacaaa gccctcgttc agactttgcc ttttatgatt ctctggtaaa aattaaaata
    82561 tccccattat agaaacgagt cgcgactatg tgttttcccg ttatcgatat aagacgtatc
    82621 attgatgccg tggatagaaa atcgaccgtt tgcataagtg acctttgtta cgctgccatt
    82681 taaaagccca gcacgaacag gctgtttagg atcgatcaga ttaagcaaaa aggcgatcgt
    82741 caaaccatga gatacgacta aaacatttcc accaccattt ttttcgcagt gatgggcgat
    82801 atcttcaaat cctgtccata cacggtctcg caatgtttca taagtttccg cccacccagc
    82861 ggtatctaag ttgtatacag cattagcaat ttgttcaaaa gaaacttctg tggtaaacat
    82921 ttcatcatat gttttaaaat tcaatacacg agggatcaca ccccacattt ccatgtcata
    82981 tccaccttca agagacccga aacaccattc tctaatcctt ttttcaataa aataaggaat
    83041 ttcttttccc ttagaatgtt ctcctagaat aatacgggca gtttcgattg cacgaccact
    83101 gtcactagaa taagcaaatg aaaagtcgac attttttaac ccgcgaccta aataatgaat
    83161 gccttcttgt ccttgctttg tgaggggtgt atcacaccag ccttgtactc gttcaattgt
    83221 attgaacatc gtttttccgt gtcgtacgat ataaagtgta gtttctgtca ttttattctc
    83281 ctcctaagtc gttttaacga ttgaaaaaag gatttgtcct tttttcctgt tcaatcgtcg
    83341 ttgcatcgcc atgtcctgga tagactgcaa attcatcagg taatacaaac agctgggtcc
    83401 gaatactatg aagtaattgt tctaaattcc ctgtatacag atcggttcta ccgatacttc
    83461 ctctaaacag ggcgtcgcca gaaacgacaa aatcatcaaa aataaagctg acgcttccta
    83521 tagaatgccc tggggtaggg acgacgcgaa aagacatgtt tcctaaagta taagttttca
    83581 tttcaaattc atattctgca ggcgagacaa taacatcagc aatatcatca tgtctaccga
    83641 gtccagaaag attcaaaatc ggatcaccta gccatttttg ctctagtggg ctgacataaa
    83701 ctgggatttg ataatacgcg cgtaaaggtt ccactgcacc gatatgatcg tagtgagtat
    83761 gggtaagcaa aatcgctacc ggctgttggt ttgttttttt gatttcttgt ttgattcgtt
    83821 ccgcatcttc tccagggtca atgatcaaaa gtgcttcttc gttgtagacc aaataacagt
    83881 tttcttcaat cattcctgtt tttaatcttt cgatatgcat gtgcattcct ccttgatagc
    83941 caaaacttct ttcatccatt agtataacgc attcattgct aggaaacaaa aacaggtact
    84001 tatttctctt tacttatctg aattatcaga ctatatgaaa agtatttgga tattctaaag
    84061 agaaggaaag taagttttca tagcatttta atatgtcctt gttacattag attcatccaa
    84121 aaatccaaat tctatatcct atatccctgc ctaatcagca gggtgttttt ttatgtttgg
    84181 aaagagagct ctttttgcta aactaggttt tttcaggtaa tcttagagag aaagaggtgg
    84241 tggaaatgat caaacagtca aaaatatctg tgcggcactt agtagaattt attttgcgac
    84301 gtggaagtat cgacaatcgt aaaaaaagta accatactgc attagaagga gcgagaatcc
    84361 accgcaagct ccaaaaagat gcgggagaaa actatgaaaa agaagtcttt ttaaaaacaa
    84421 cagttcaatt agatgaatat tacctgatcg ttgaaggccg tgcagacggt attttcaaaa
    84481 gagacggtat ttattatata gatgaaatca aaacctccga accacgattt gaagatttag
    84541 aaccagaaca agtggaactt ttctttcatc aagcaagggt gtatgcctat atctatagtc
    84601 aagaacatga tttacaagaa ataaatctgc aattgactta cttccagacg gcagaagaag
    84661 tgatcacgag aaaggttgaa catcagacaa gagagcagtt agaaactttt tttaaaaagc
    84721 tgactgaaga ttataaagaa tggcttgttt ttcaagaaaa ctggcgcact gtacgcaatg
    84781 cctctttgat ggctttgaaa ttcccccatg atgagtatag gaaaggtcag cgtgaactag
    84841 cggtagctgc ttataaaacg atccgtacga aacagaaatt gtttgtagaa gcacctaccg
    84901 gaacaggaaa aacaatctct acgttattcc ccgctttgaa agctgtaggg gaagaagagg
    84961 gagaaaagat cttttatcta acggctaaaa caataactag acaagtagct gaagatgcta
    85021 tgacagcatt aaaagataca ggagctgaag taaaaagtgt cactttgacg gcgaaagaca
    85081 agatctgctt tttagatgag acgacctgta atccagatca gtgcccatat gccaatggtt
    85141 attacaatcg gattaatgaa ggtttatggg atcttttgaa tcatgagaat cagatcactc
    85201 gtgaagtcat cgaaacttat gcaagaaagc atacactttg tcctttcgaa ctatcattag
    85261 atgtcagtat ctggtgtgac gtaatcattg gggattacaa ttatttattt gatccaactg
    85321 tttatttaag acgttttttt gaagatgaaa aaaacgagga ctatctgttt ttgattgacg
    85381 aagcacataa tttggtgaat cgttcccgag agatgtattc ggcagaacta tcttatgaaa
    85441 aaacgaaacg aagtaaggaa gctataccaa aggaattcaa aaaacttcat cgccgtttca
    85501 acaaactatt aaaagaattt gattcgatcc gagaaatagc aaaagaagat cattgggatt
    85561 atcatcatca aaaagcaccg gctgaatctt tagtaaaggc aggttatcaa ttaagcgaaa
    85621 aaattaaaga atggctggca gaatttcctg agcacccatc acaagaacaa ttgcttcctt
    85681 attattttga tttgcttcat tttttgaagg tcagtgaatt ttatgatgat cactacgaaa
    85741 caacagtcga aaaaacgtat cgcgatctga tagtaaaaga gttttgtatt gatccaagct
    85801 tgtttcttga gcagtcgttg gataaaggaa aaagcagtat tcttttttct gctagttttt
    85861 caccactctc ttattatcag gaaacactgg ggggacaaaa aagtctggct tacaaactgc
    85921 cgagtccttt cccagaagga aaccagcaag ttttcatcgc aaattaccta gagacgactt
    85981 atcgaaaaag ggaacacagt ctggcaaaat tagtagagac gattcatgct tttgctgatg
    86041 gaaaggtcgg gaattatttc gttttctttc cttcttatca atatttagat cttgcggtgg
    86101 aagcattcag acagcaatat cccgacagca atgtgctaat ccaagaaacg gacatgaatg
    86161 aggaagaacg cgaacgattt ttaacaaaat ttcaaacaaa tcccgctgaa acattgattg
    86221 gattttgcgt acttggcggg attttttcag aaggaatcga tt
//
LOCUS       DAFEIE010000005        67760 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFEIE010000005
VERSION     DAFEIE010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.005"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(98..1228)
                     /locus_tag="LP345_000414"
     CDS             complement(98..1228)
                     /locus_tag="LP345_000414"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBL1759226.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3078)
                     /locus_tag="LP345_000415"
                     /pseudo
     CDS             complement(1877..3078)
                     /locus_tag="LP345_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(3138..3341)
                     /locus_tag="LP345_000416"
     CDS             complement(3138..3341)
                     /locus_tag="LP345_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBL1759227.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEQLFHIQVAE"
     gene            complement(3483..4715)
                     /locus_tag="LP345_000417"
                     /pseudo
     CDS             complement(3483..4715)
                     /locus_tag="LP345_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4878..5690
                     /locus_tag="LP345_000418"
     CDS             4878..5690
                     /locus_tag="LP345_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759228.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6714..6911)
                     /locus_tag="LP345_000419"
     CDS             complement(6714..6911)
                     /locus_tag="LP345_000419"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL1759229.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7057..7935)
                     /locus_tag="LP345_000420"
     CDS             complement(7057..7935)
                     /locus_tag="LP345_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1759230.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7974..9092)
                     /locus_tag="LP345_000421"
     CDS             complement(7974..9092)
                     /locus_tag="LP345_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBL1759231.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9089..11188)
                     /locus_tag="LP345_000422"
     CDS             complement(9089..11188)
                     /locus_tag="LP345_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBL1759232.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11239..12060)
                     /locus_tag="LP345_000423"
     CDS             complement(11239..12060)
                     /locus_tag="LP345_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1759233.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12057..12866)
                     /locus_tag="LP345_000424"
     CDS             complement(12057..12866)
                     /locus_tag="LP345_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1759234.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12887..13381)
                     /locus_tag="LP345_000425"
     CDS             complement(12887..13381)
                     /locus_tag="LP345_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1759235.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13393..13881)
                     /locus_tag="LP345_000426"
     CDS             complement(13393..13881)
                     /locus_tag="LP345_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1759236.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13958..16654)
                     /locus_tag="LP345_000427"
     CDS             complement(13958..16654)
                     /locus_tag="LP345_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1759237.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17082..18155)
                     /locus_tag="LP345_000428"
     CDS             complement(17082..18155)
                     /locus_tag="LP345_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1759238.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18152..18979)
                     /locus_tag="LP345_000429"
     CDS             complement(18152..18979)
                     /locus_tag="LP345_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759239.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18980..19786)
                     /locus_tag="LP345_000430"
     CDS             complement(18980..19786)
                     /locus_tag="LP345_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759240.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19798..20883)
                     /locus_tag="LP345_000431"
     CDS             complement(19798..20883)
                     /locus_tag="LP345_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759241.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20900..21442)
                     /locus_tag="LP345_000432"
     CDS             complement(20900..21442)
                     /locus_tag="LP345_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1759242.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21700..22689
                     /locus_tag="LP345_000433"
     CDS             21700..22689
                     /locus_tag="LP345_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBL1759243.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22686..23423
                     /locus_tag="LP345_000434"
     CDS             22686..23423
                     /locus_tag="LP345_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBL1759244.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23420..23971
                     /gene="coaC"
                     /locus_tag="LP345_000435"
     CDS             23420..23971
                     /gene="coaC"
                     /locus_tag="LP345_000435"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBL1759245.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23987..24619
                     /locus_tag="LP345_000436"
     CDS             23987..24619
                     /locus_tag="LP345_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1759246.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24704..25351
                     /locus_tag="LP345_000437"
     CDS             24704..25351
                     /locus_tag="LP345_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1759247.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25356..26339
                     /locus_tag="LP345_000438"
                     /pseudo
     CDS             25356..26339
                     /locus_tag="LP345_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
     gene            complement(26742..28256)
                     /locus_tag="LP345_000439"
     CDS             complement(26742..28256)
                     /locus_tag="LP345_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBL1759248.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28394..29200
                     /locus_tag="LP345_000440"
     CDS             28394..29200
                     /locus_tag="LP345_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759249.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29375..29944)
                     /locus_tag="LP345_000441"
     CDS             complement(29375..29944)
                     /locus_tag="LP345_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1759250.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30027..32087)
                     /locus_tag="LP345_000442"
     CDS             complement(30027..32087)
                     /locus_tag="LP345_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBL1759251.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32364..33842)
                     /locus_tag="LP345_000443"
     CDS             complement(32364..33842)
                     /locus_tag="LP345_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759252.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34140..35075)
                     /gene="murB"
                     /locus_tag="LP345_000444"
     CDS             complement(34140..35075)
                     /gene="murB"
                     /locus_tag="LP345_000444"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBL1759253.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35148..36068)
                     /locus_tag="LP345_000445"
     CDS             complement(35148..36068)
                     /locus_tag="LP345_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1759254.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36181..36933
                     /gene="xth"
                     /locus_tag="LP345_000446"
     CDS             36181..36933
                     /gene="xth"
                     /locus_tag="LP345_000446"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBL1759255.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37797..38330
                     /locus_tag="LP345_000447"
     CDS             37797..38330
                     /locus_tag="LP345_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBL1759256.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38820..39344)
                     /locus_tag="LP345_000448"
     CDS             complement(38820..39344)
                     /locus_tag="LP345_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1759257.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39337..39810)
                     /gene="tsaE"
                     /locus_tag="LP345_000449"
     CDS             complement(39337..39810)
                     /gene="tsaE"
                     /locus_tag="LP345_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBL1759258.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(39933..40913)
                     /gene="pta"
                     /locus_tag="LP345_000450"
     CDS             complement(39933..40913)
                     /gene="pta"
                     /locus_tag="LP345_000450"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBL1759259.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41066..41746)
                     /locus_tag="LP345_000451"
     CDS             complement(41066..41746)
                     /locus_tag="LP345_000451"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL1759260.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41872..42741
                     /locus_tag="LP345_000452"
     CDS             41872..42741
                     /locus_tag="LP345_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1759261.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42767..43282
                     /locus_tag="LP345_000453"
     CDS             42767..43282
                     /locus_tag="LP345_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759262.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(43329..43922)
                     /locus_tag="LP345_000454"
     CDS             complement(43329..43922)
                     /locus_tag="LP345_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1759263.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(43947..44126)
                     /locus_tag="LP345_000455"
     CDS             complement(43947..44126)
                     /locus_tag="LP345_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759264.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(44203..44712)
                     /locus_tag="LP345_000456"
     CDS             complement(44203..44712)
                     /locus_tag="LP345_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759265.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(44808..45188)
                     /locus_tag="LP345_000457"
     CDS             complement(44808..45188)
                     /locus_tag="LP345_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1759266.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            45518..46267
                     /locus_tag="LP345_000458"
     CDS             45518..46267
                     /locus_tag="LP345_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBL1759267.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(46451..47728)
                     /locus_tag="LP345_000459"
     CDS             complement(46451..47728)
                     /locus_tag="LP345_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759268.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(47807..48451)
                     /gene="pcp"
                     /locus_tag="LP345_000460"
     CDS             complement(47807..48451)
                     /gene="pcp"
                     /locus_tag="LP345_000460"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL1759269.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(48650..49594)
                     /locus_tag="LP345_000461"
     CDS             complement(48650..49594)
                     /locus_tag="LP345_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL1759270.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(49596..50282)
                     /locus_tag="LP345_000462"
     CDS             complement(49596..50282)
                     /locus_tag="LP345_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL1759271.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            50756..51076
                     /locus_tag="LP345_000463"
     CDS             50756..51076
                     /locus_tag="LP345_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL1759272.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            51230..52135
                     /locus_tag="LP345_000464"
     CDS             51230..52135
                     /locus_tag="LP345_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1759273.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            52132..52905
                     /locus_tag="LP345_000465"
     CDS             52132..52905
                     /locus_tag="LP345_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1759274.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(53086..54510)
                     /locus_tag="LP345_000466"
     CDS             complement(53086..54510)
                     /locus_tag="LP345_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1759275.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            54721..55167
                     /gene="nrdI"
                     /locus_tag="LP345_000467"
     CDS             54721..55167
                     /gene="nrdI"
                     /locus_tag="LP345_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL1759276.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(55232..57214)
                     /locus_tag="LP345_000468"
     CDS             complement(55232..57214)
                     /locus_tag="LP345_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1759277.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(57228..58124)
                     /gene="murQ"
                     /locus_tag="LP345_000469"
     CDS             complement(57228..58124)
                     /gene="murQ"
                     /locus_tag="LP345_000469"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL1759278.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(58127..59188)
                     /locus_tag="LP345_000470"
     CDS             complement(58127..59188)
                     /locus_tag="LP345_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL1759279.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(59399..59965)
                     /locus_tag="LP345_000471"
     CDS             complement(59399..59965)
                     /locus_tag="LP345_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1759280.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(59993..61495)
                     /gene="eat(A)"
                     /locus_tag="LP345_000472"
     CDS             complement(59993..61495)
                     /gene="eat(A)"
                     /locus_tag="LP345_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL1759281.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(61753..62874)
                     /locus_tag="LP345_000473"
     CDS             complement(61753..62874)
                     /locus_tag="LP345_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL1759282.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            63000..63941
                     /locus_tag="LP345_000474"
     CDS             63000..63941
                     /locus_tag="LP345_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL1759283.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(64091..64987)
                     /locus_tag="LP345_000475"
     CDS             complement(64091..64987)
                     /locus_tag="LP345_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL1759284.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            65256..66596
                     /locus_tag="LP345_000476"
     CDS             65256..66596
                     /locus_tag="LP345_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1759285.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            66814..67257
                     /locus_tag="LP345_000477"
     CDS             66814..67257
                     /locus_tag="LP345_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBL1759286.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
BASE COUNT        19976 a        13994 c        11788 g        22002 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 acactgtctg agttttaagg aaagcttctt ccccaaccca atcgttcgat aagcacattt
     2281 agttttggga gtcgaaaagt accaatcatc ttttgtatta taaatcaatg tcttctcaat
     2341 cgttatcgtg tttttctcaa aatctacatt cgaccaagac aaagcttcaa gttctccaat
     2401 ccgaatgcca gtataaaaga gcatttcata cacaatcttc cgatggtggg tttgaatctt
     2461 atcatccttc aattcattca tcactttttg aaactcactg tgttcccaaa actcaacttt
     2521 cttattctca gaaggaagcg aagaaacatc ttcaacggga tttttagcaa tcaccccctc
     2581 tttaacagcc cgatccaata caatttttag gtgccctcga atccgattga tataagattt
     2641 tgataacgtt tcgccattaa cttttttccg tgaattacgt gactctgtct ggcttagttc
     2701 aaataaccaa tcctcaatat cgtgacttgt aatatctcga acacgaaaat gatagaaaaa
     2761 ctgcatacgc ttttcgaaaa tgaattgcgc attctcatat gtttgacttt tgacctgtct
     2821 ctcgtaccat tttacaaacc tatccttgta aaactcttcg aaagtcattt gattggtaga
     2881 acacagttga ttaggaattg tcttgttaaa atcatgtgtt tccatgtact tgtcataagc
     2941 aattttggca tctttttgtg aagcataacc tcgtttagtc ttctgaacct ttcttccatt
     3001 ttcatctata cctagatacg ctcggaagaa ccattttttt gtctttttat cttggtaaat
     3061 atttttaatt tttggcatcg ttccattcct ccctgtactt gagaaaagct actttaatag
     3121 taccgcgctt gtactgttta ttccgcaact tgaatgtgaa aaagctgttc aattactcgg
     3181 gatggcacca caccaacttg gcgattatta taaaaatcaa taccttcaat ccttgcaaga
     3241 tatgccttgc tctctttaat cattcgtgca gcttgactag gtttaaagcc catctctatc
     3301 aaaattgcac gatttaccat gaaatcacat tttgtttcca ttctctcacc tcctgattct
     3361 ttactccttt taaaataatc ctctttataa tctattgttt ctcattcgat ggttgtgtta
     3421 tactcgtctt gtcgaggcgg agtacgttgc acaacttgtt gtgtaagcag tactttgctt
     3481 ttttagtagc ttgttttctc atttgatata ctttgtaatt ttcgttcata atactcaacc
     3541 tcctcctgat aatactccgg gtctgccttc atattttgga gaagtttgat ctgtcttgga
     3601 ttcatttctc cttgttcaat aatcaaaggc aacaaggaag aatgaaacgt ttgatcgacc
     3661 tgtgcaataa aaactaatga tggtgaaaca ccatgaatta accaactcat agttttctca
     3721 aaactttgag gaattgtatc taaagaaatg gtgattgcgc cataattgct aataaaggct
     3781 gcccatttgg catcaacttt tgcacctaga tcatttggat cacggtcata aaaacaaatt
     3841 gctccattaa gtaactcaaa gaacagtttg gttaaatcat gggtttttga aataatcttt
     3901 gccaagcttt gcgctttctc ttttcgatac cgtagttcaa agcgattctt tacttttgcc
     3961 tcttctaaag gaattcctcg tcgcttccgt tgttcatggt ccttctgata aaagcaaaaa
     4021 cgacactgac tcttctttga gcctaaatac aaggtctcac catttgattc attgtttatg
     4081 atatccgtac cgccatgaga ttcactcact tgaaaagtgg tccacacatg gcctagtatt
     4141 accttatgct taagttctgg aatgctgaga ctccccacaa aatcatctaa agtaaaatca
     4201 atccgtgtaa agttcccctg ataatctaat accttacgaa aaaactgttg ccaatttgtt
     4261 tttcgtgttt ttagccatct tgctaagtgt ttacagcctt gacctgaaaa ctccatcaca
     4321 gttcctttaa ccgcatcgtc aatggaatac cgaatcgtga ttacttgatt ccacacgtat
     4381 tggccaatat agccctttgg cgcataatcc agttcctcaa aacgttcaat gggcatttca
     4441 ataatctctt caattagctt taaatgttga ttcgagaaaa agtgaatggt tagataatca
     4501 atcaaaacac ggttaactgg aacgacctct tcttgcaaac tatccaacac aagattcaat
     4561 ttttcttcac ttaattgtct cgttcctttt tctactttcg ataataacta tctcgaaatc
     4621 cccacttttt ctgctaaata tcgttgtgtc cacccccttt cttctcgaga aactcgaatg
     4681 gcttcaccga gatcatgttg attaacttgg ttcatcgaca aacctccttc tgctatttac
     4741 ttgtcaaaga acctattgaa cttattttaa gtacattttt attgtacgcc tgtatttatt
     4801 ttaagtcaat atgttttgac tttttttaag tacacacgta tactaaattt aagaacttat
     4861 cctgaggagg agttttcatg gagatagaca agcaagcagt cggcaatcga attcggcaga
     4921 ttcgccaaga attaaagttg agtatggaga aatttggcaa actaattggt gatttaccgc
     4981 gaagtacagt caataactgg gaacgtggga tcaaccttcc aaaaaccgaa acccttcacc
     5041 aaatcgcaga gataggtcat gtcaccaatg aatatctttt gtatggtgat caagagaatc
     5101 aatacatttt agaaatgctc caaaaaaagg caggtaagct tgatcctaag attgaaggtc
     5161 tcatagtaga cgaaatcaaa cacgctgacc ttgttagtga aaaagaaatg gatcgaatga
     5221 ttgaattttt tattacaaat ctcattccac caactgaaca agaccagttt actttccaat
     5281 gtatcgatga aaaaaagcag ctttatcttg gttcaactaa ttttggtaag gaagcccagc
     5341 tctatttgca acatgataat caaaatcata ttctgcacat gatgcccttt accttctcca
     5401 actttagtgt ggatcgcata ctcgtctatt tagcaaatca aaaatcctat tcctattttg
     5461 ggaaacattt acccaaggaa ctaggtgaga aagccatcct tctatactca attaatcaat
     5521 tgaccagcga tgtgcgaatt gccccgttgg tctattcaga agaaaccgct tcttatcagt
     5581 acacagagga caatcaatat ctactagaac agcaatatct ttatctacca ttcgtgatgg
     5641 aagtcgagaa agaacgcctg ttaaatgcag cgtatccatc atcaaaatga ggtgacaaaa
     5701 ttgataagca cgtgacaaag aaaatactgc taggacactc cccaatgggt agttgtcaca
     5761 gtttcctgtt ctttgttagc cccctgttag aaccgggggc tttattcctg cagtccggct
     5821 acgccttcct gcaatagaca aaactccaga tcgggtaatt cgcttgtggc gaaacccgac
     5881 ctggagtttg tctctgtatt ttgaacccta aaaattaatc aaacagactg atattctcat
     5941 aatcagcgcg aaataagcca ttaagtacag ttttcctacc tatttttgat aacccgctgg
     6001 ttagttaata ttccttttcc gagagagata aatgattggt taaatctata tacatctcaa
     6061 cctttaaaaa tgttttcgaa atacttcatc agtacatgtc atacaaatta ccagtgcatt
     6121 ctcaaattct agttctttaa ttgatttcag ttgaggagca gttacttttg gcggaaattt
     6181 ccatttttgt ccaaacctct tcccccgatg aaatttcttt gttgcaatta ttgcaatgaa
     6241 aaatttttgt ttcaaaaata tacataatta cttcctccaa taaaaactat ctacctctca
     6301 aattattttt ctctaataag aaaaacagaa aaggtaataa gatacaacag tgatgattcc
     6361 taataaagaa aagactacaa taatattttt ctaacttatc gccttcaaag aaatagtttc
     6421 ttatttttca ctaaaataaa aaatttattg caaaaaaaat agaagtgaca aaattatcaa
     6481 tcatttcaag gtaatataac tacctgagtt tattatcgat taaaatgcta actacatttg
     6541 caagagaagc gagagttaaa ggtaaatata gaatttctac ttttttagca atagaaatag
     6601 gaataaaata tttaaaatgt atagaaactt tctttttttt tcttgctatc tttttataat
     6661 cacaactctc tataatagaa ttacgattta ttttatacgg ctgaaaaaat ctatcaccaa
     6721 aaaaattcaa acattaagcc aaggattatg aagtcaacat ttcgaaaaat gaacatacat
     6781 tggtaagcaa ctataactat taccacagac ataaagtaac acaatatatt actatttaag
     6841 tgtacgccac cagtgaatat cctcaaggta tacagcgcac aacaaaaaga aaaaaggaaa
     6901 cgcagaagca tttcctttca gtgatttaat gaaaacaaca cgatttgact tagagccttt
     6961 ttatttgaat tcattttcgc tttatccaac ttcatttgat catttgatta ctcggttaaa
     7021 tacttttgac atgagtatca atgaaacatt cattaattat ggttgcttat ttcttaccgc
     7081 ttttctggcc aatgctaatc cgccgattat tccggcatta tcacctaatt cgggcgtaat
     7141 aatgtagcta tcaattggtg gtatttcaac atatccattt ataagctcaa caaatttatc
     7201 ctgaactttt ttcttcatgt gttcttgttt cattacacca ccgccaaaaa taattctatc
     7261 tggcgaaaac atcagtgttg tattgtatgc acattgggca aggtaaaagg cttcaatctg
     7321 ccaaaacgaa tcgtcagcca ataaattctg gccttttaca cccaaccgtt tttcaatcgc
     7381 tggtcctgct gccatcccct ctaaacaatc ttggtggaag ggacagtttc ctgaaaaatt
     7441 gtcctttgga tgtcgcttga tcaacatatg ccccatttcc ggatgactga acccttccac
     7501 gaaagtccca ttgaacaagg caccacctcc gatacctgtt cccacagtga agtatgcaac
     7561 acctgctaac cctttgccag aaccagcaac atattcacca tagcaagccg cattgacatc
     7621 tgttgtccat tcaatcggaa tattgaaata ttgctttagc gttcctacaa aattgaaatt
     7681 ttgccaagca agttttggtg ttgatgtgat atgaccgaaa ctcgttgatt tgcattgaat
     7741 atcaattgga ccaaagcagc cgaccccgat gcctgccaat tgttccttaa aaggtttaaa
     7801 aaaatcaatg acctgcttca ttgtttcaac tggagttgtt gtgggaaaac tgactctttc
     7861 caaaatcgtt aattcctcag taccgactgc acagacaaat ttagtccctc cagcttcaat
     7921 tgccccatat atcatcatag gttcctccct tcgaatatgt gaaaaacact tcattaacgc
     7981 ggcaagcgtt ctcgatcagt gaaatgacgt ttagtatttc ctgaagcttc tgttgaatac
     8041 cagtaagcga cactagcaac atcgtcttgc cgctcaaata agcgaacatc atcgttgccg
     8101 atttgttgta aagtgaccga taaatcttcg gtaaaacaga tggggtcttg aagatgccaa
     8161 cgataaagac catgtcgtgg cattgcgtcg tcaccaaagg catgaacggc attcaatttt
     8221 cccgtttcaa aacgatctct tgtggcatct ctatttgatt ggtaaggata ccctaaaaag
     8281 gctgttgaat agtttttcgc atgtggacgt ccgaactcat cgtactcatg aaaggcccac
     8341 gccccgccaa aataatcttc tgaacctgtt gaggttacgg tcggatactc actatcccca
     8401 tcaatgtaga atttaaactc gccttcgccc caccaataac gttctaggca ggtaagcgca
     8461 aggtaagtac ccacgtaata gccttgaccc tttaatcgat caattaactt ataatcctcc
     8521 tgtaatttgg taatgcgttc ccgatgccaa tttgcgtgaa aatataggct attttcttcc
     8581 aattcgtcca ccaaagcgta atttatcgta taaaaaaatg aggacatatc cttcggatgt
     8641 aaattctcga tcgtaatttt agcggatgtt tggaaaggca tttcgaaata ggaattaaag
     8701 ccccctgtag gattaaccac tatcggcaac gagttcacct cgcaacgctc tccaaaccca
     8761 ttacaaaaga aatcccctaa aggactttca acagcagggc tatccgaccc atcccaataa
     8821 attcttaaga ttaaatcacg taaaacaaaa ctgccaaatt ctgttcgatc acgaatcgtc
     8881 atccacatat gacgaattat tcccgttcca gtaatatccg caatcacagt ttcttcacca
     8941 gaagtcagcg gaattgcgcc acgacctttg cggcttggtc ctagctcgct tggcaacatc
     9001 gcagctttac ctttctcgcc tgttggattt tcgggagtga ttgctcgact ctggattttt
     9061 ttaaattggg taatattttt tagtatactc atctttttct cctttgaatg tgaatcgttt
     9121 ttcccttttc tacgtgaaga atttttttcg tatcacttat tttcaatggc ttttctgaca
     9181 aatttgaaat actcaactcg gattgcgtac attcaatcga aatgaaggct tgaccgaact
     9241 tcaaattctt ccaagaaaac gttaaattat caacaggatc aatttgcaat actccttttt
     9301 tgaatttcaa tccgaaatat tgactgatca ttaggctgac aaaaagaccc gatgcccagc
     9361 cgcatttgcc gcagccaaag tctcgcacga cttctccttg ttgagcctct aagcgatacg
     9421 gccaccacca ccacgaaccg tctaaatctg ccaaacaaat tagttcttct aatcgggtta
     9481 cgaaagcttg agggttgtgc agctcgctca ttaaaacagt gataaagcca ggaaaagtgg
     9541 cgccggattc taatccccaa gtgatgcctt tgatttcctc gctataggtt ggattgaaag
     9601 aactagcaga aaaggccatg gtgttctgat ataaatgatc tttattatct aaaaattgat
     9661 aaaaaggcat caacgtagtg tctgattctt ctccatcatg catcaataaa ttaatttttc
     9721 catccacaat cacatcactt aaaaagatta acccttgctc aagaatcggt ttttgatagt
     9781 gcttcactga ataggttgtt ttctcctcat caccgattcc ctccaaaaat tgctcaccaa
     9841 aaggaccatc gatagtcatt tgtttacaaa ttgattcctt tagtttacag gcaatgtttt
     9901 tgtatcgctt gctaagactc agttgttcta gggcttcaaa aatttctgca agtccaatac
     9961 aggccttcca aagacaaaga ttgctgccgg tatgatactt tccaagtgca aaggcgtctg
    10021 ataaccaaac agatggaaaa agcattggtt cccctgaccg acgttgagct aatatgtcct
    10081 caataattct tgaagcattc agtagaacct gcggacaccg ctcaaagaat tttgtatccc
    10141 cagtatgttc aaaataaaga ctagccagta acgcactgga taacgaatta ctcagagaat
    10201 gattgatacc tcctgtaaat tttgaaccag gaaacttaac gccatattga tcaaaccata
    10261 gaaccgtttt ttgacataac tccggttcaa acatggtgaa tggcaatgat gcgtaataca
    10321 tatccttatt ccaaattcga ttagtagcag gatagctgcc ccaattgctg ccgacgacct
    10381 gtccctgtcg attcataccg aaactagaaa agctttgata aagtgcacga cgatagagat
    10441 ggacaactct atcgtttggc attgacagct gcccaaatag ctgagcaaaa tagttcaatg
    10501 tttccttcag ccatttttcg atatcagatt cctgaaaagt cattacttct tcaaaagcat
    10561 ttgggtccac aaaagcaatg gcgaagcttg ccacttcctg ttgtgcgatc gtgtccttat
    10621 ttcctttttg agaaatcaac acattttgct gatccgaata cttctcttga tacgaaggca
    10681 catctttcac tgaaacttga aggctttcgt gtgtttcatt cacaatgtaa acctgttgaa
    10741 caagcatact taaacgctta ttagccagta tgggagcaaa ggatactaca atgaccttaa
    10801 acgtcgaata atgatgaata tatctaggca aacagtcttg aatcacatcg acttcaatac
    10861 gatgatccga ttctgacaaa tggtagacaa tcccgtttac ttcaaccttt aaggataacg
    10921 aattggtttg agagagctgt ttattgaccc aaacacctgg tttttcctca gttagtaaat
    10981 tttctcgata aaaggtcaac gtttgaatcg tcccgcaaac atcaaggttt gctaatgtct
    11041 tttgattact tacatcgaag gtcaatccct ttacatcagg aatattccga tagtagctgt
    11101 attcgtttga agtagtcaca tttccgtcgt ttaactcagc attaaaaaat gggtgtttgg
    11161 gtgaataaat tacttcatta atagtcatct tttccctcct tgctaaaaaa actgcagcct
    11221 agtagctgca gcttcctact atgcgattcc aagtaatgac aataaaattc ccaagacgac
    11281 cattccaaaa ataattttga tgacgccgac ttttttatct agtaatttga aacagctcaa
    11341 tgttaccaat aacggtacaa ttcctttaaa aatactatcg aggatttctt ggacattcat
    11401 tagttcttcg cccttcattg aaaagctcaa aacggtattg aatttgacca tactgatcgt
    11461 cattgcacct accatgatca gacccaagat actagcagct tttgtcagaa tttcaattaa
    11521 cccgttcgca tacagctttt caatatattt agagcctaat gaatagccta aaacgccgcc
    11581 atagtatcgc atcaagtaat taggtatatt gaacataact aaaaagataa ttggtgccaa
    11641 aatatttccg gcattggcta agttgatcgc tagtcccgcg gtaacgacac gccaaactcc
    11701 ccagaacaat gaatcgccaa ttccagccaa tggtcccatc aaactcgttt tgatcgcgtt
    11761 gatactttcc acgtcaaaac cagctttttc agaattttcc ttctccatcg atgccgcaat
    11821 ccccatgaca aaggacgcgc aaggaatggt cgtcgaaaaa tactgtgtat gacgttccag
    11881 cgccgcagct cgatcttctt cacttttgta gaaatgatta atgaagggca tcatagaata
    11941 ggcgaaacca ccgccgccca tcgtcaccgg attcaccgaa gcatacatag tcatcgagcg
    12001 ccaaaacatc ttccgaacca attttttctc atctttagaa attccatcag ctaatttcat
    12061 tgaaagaaat cctcctcttc ttggtcaagc gttgcattta cagcagcatc gctttgaact
    12121 gcatgaacag atatattttt tagttgtaga tctctttggg ctataacaat tgcaataatc
    12181 gttccaactg cggcaattgc aatcaatggt aactcgagat acgccataac aacggcccca
    12241 aagaaaaacc acacagcaat atttttactc caaagcatcc gtaacagcat cgccatccca
    12301 actgccggca gcagatttcc agcgactgtt aatccgttca tgatgacctc tggaatatta
    12361 tccaagacgc ttttgacaac atctgctcca aataaaacgg caaagaatgg aataagagca
    12421 taaagcgcat agtggacaaa ccacataaag aagtgcagat tgatgattcc tttttgatca
    12481 ccagattttg caaatttgaa aaatttagca gccatcggtc cacatacaaa agaaaaaatc
    12541 atattcatta actgtaatcc taatactgct agtggaaaga caatgggaat aatcgcatcc
    12601 acgtttcctc ccattttgat tgcgaacgct gtagccagcc cagcagccaa agaaggctcc
    12661 gccgtactag agattccgat attgacgaca cccataaaga tggcttctag tgacgccccg
    12721 acaatcaacc ccgtctgcaa atcccccatc aacgctcctg ctaacggagc aacaacaatc
    12781 ggacgactca gcatggacat cccgaacatt tcatgtccag caactccaat aaaaacggcc
    12841 aaagcgacta caaatgcatc atacataatt tttctccttc ctttttctaa aaatcactca
    12901 aaatagagat agctgaacgt ttttccatcg ccggtgtagg ctgaaaaacg gtatctggat
    12961 aaagttcaac taattctttt aagtcttgaa tttctgacgt cgttaacatc acttcctttg
    13021 ataaggtttt cttatcttcc gatggcggtg tcattttccc agcattcccc acgttcatta
    13081 attcgatttc cgttgggaaa gctttcgcaa cttttaccgc atctttgaca ttagggacta
    13141 aaaccatcaa gcgcatgtcc ttcgcccgcg gatcttttaa caaatgaatc gcgtcatcaa
    13201 ctgttttaat aatgactttg acattcgatg gtgcagccat cttcaatgtc atcttttgaa
    13261 tatcgttggt agccgcctca tcgcttgcta ctactaaccc ggttaaattt agactctttg
    13321 tccaagtcat cgctacttgt ccatgaatta atcgttcatc aattcgcact gctttaatca
    13381 tttttcttcc tcctaaaaaa aatcttcctc ttcatttact acatgtacct catcaagaat
    13441 ggtcatcttt aattcctgtt ggcatttatt taccagttcc tgaatatcct cctttgttaa
    13501 ttccttggtt gccaatacta tttcgagcag aattggcaga ttaaagccag acaaaatagt
    13561 tacagcaatc tctttctcca aaaaggtttt ggtaatcttc tgattgacac ttccgccaaa
    13621 taaatcggta aaaacaaaaa tctgatcctg ctcgttcacc tggtttacaa atacattcaa
    13681 ctcctgttca aaatcacact catccacata agcattaatc accgtaatct cttgaacctt
    13741 ccccgtcagt aattgaatac tgctaagaaa gcctgaagct aagtgaccgt gagtcgctat
    13801 tagaattttc ttcatatggt taattccttt ctttctgttc acttttatat aagcaattcc
    13861 tgtgccaact tttaaaaaca ttggtttaat cacgttaatt cacattaaaa aaagtgtcta
    13921 acctaaaaaa aacagattag acactttttt agacacttta tttttgaata tacggtccta
    13981 ataattcata gagcagcgaa agctcataag cattgacttt aaaattatat ttcatctcca
    14041 ttgattgaaa aatacttcta gaaacataat aaaattcatc ttcatctggt ttcaaatcat
    14101 aattcggttc ttcagatttt tctgtccgag ccaagaataa acgttccatc atcaatgccg
    14161 tatgcatata gagatttagt tttacacggc catttaaagt gaaatgatag taattttcat
    14221 atttagaaat gactgtttcc acttcactca tcacgatcgt tgggttcaga aagttcaaac
    14281 ggtccgcaat tccttccaac gaaaagaatt ttactagctc ctgaatcaag cggttaaatt
    14341 ctgccggctt catttcagga ctcaaaatat gctccaaatt ggctgctcca tcaccgtcta
    14401 agatgtcata aacattaata ttaggaattg aaaaggaacg tggaagatcc gaagtcgtga
    14461 tgaccaattt tgtcttgtca aaataagttt catcattttg gtcgattaat tcacgtagtt
    14521 ctctgtagtc cttcgtgaaa acttcgatgg attcatccga taaatgatga cgaaaaacat
    14581 ctttcaattt gtccgaaatc cccaaacccg acatacagga aatgataatg ttgctacttt
    14641 gagaaaagcc ttcaaagtat tgaacattga ttgaatactt gtctgctgca tcctccgcaa
    14701 tctgtttaaa tggcgcattc atcgtcatct tcaagccaat atcaagtgca atggaagtcg
    14761 tcaaattatt cagaagaagt aactcccctt ttaaatcgtt cttgatctgt gtgtaaattt
    14821 gatttaaaga gcccatatct acgatcagca ctagactatc tgtattcact tgccgtttca
    14881 cgaaattcct tgtcgattcg acaatctctg acacattact ctctactggc atatccaacg
    14941 cttcaaaaac ataattgccg cataattgat tcactactgc ttgaatgctg ctagccgtac
    15001 tatctccgtg agcaagcaac aggcccttca gctcgatgga ttcatctaca taatcagata
    15061 aagtcacgac aataagcagt cttagaaagt tctcgtcctt ttctgagagc ggtggtaaat
    15121 gctccaagaa ctgattacat aagtaagtcg tccgaggtag atttgcagct aatgtacgat
    15181 ttatcccggt taagtctgtc ttatagcttg gggaaatgac ataggatctg ctaataattt
    15241 ctgcaacagg tccactcgtc gtcaatccgt acgtttttcc taaaacggat acccagacct
    15301 ttctaaacat ctgaatcatc aattttctac tcattgataa aaaagaatcc ttatcaatgt
    15361 gatgcaccaa atgctgtact tcattcttta tcgaagaaaa attttcattg aaattacctt
    15421 catttatcag ctgagtaatt ttttccaaaa tcgaatcata atcaaacggt ttgattcgat
    15481 ccgtttttat cttttgattt ttctttatca ataaactagc aatcggcaag ctttctactt
    15541 cggattccag catatttaac tgaatcaaga tctcattttt cccaatcgtt aatggttctt
    15601 cttgtgttcg actatacaca tccgcacaac tgattttaat gatattcttc agcttaccaa
    15661 tattcccact aaagggatga gataacatta aagacaaggc ttctcttgaa acaataatat
    15721 ctttttgtaa aacatccgct tcattttgaa aaaataattg aatcagctct aatcgttctc
    15781 gaatggggcg atcttcaaaa gttggcaaca taacactaat ttgaatacgc cgatcaaagg
    15841 tgtctaataa ataattttca cctttttccg tcgtggcgaa aataaaacga accttagcag
    15901 aatgccaatt tacattttca ccgactggac gatagtttcc agtatcaata aatagaaaga
    15961 gcttttcttg attttctttc gataggcgat ggacctcatc gagaaaaaga tagccgttgt
    16021 tggccgttgc caataaacca tcggtatcct tttcagcccc cgtaaaggcc cccttcttgt
    16081 atccaaacag tgttgccgaa agcagttcgg gattgtccgc ataatcggca cagtttaaga
    16141 tagcaaatgg tgcatctttt tcaataattt gctcatggat agcgtattca aaaatttttg
    16201 tggctaaaaa actttttcca acacccgtgg ctccatttat taatacactg agtccgttag
    16261 gcggatattt gacagcggct atacattttt gaatgacctc tctcagactt ccgtcatgac
    16321 caactacaga atgaaaggct tcgtttattt gctccgtatt atctacaacc gcatattcat
    16381 ctaaaggctt ccacaaaaca ggctttcccg gtaatttctc gaccttttta tcttccacta
    16441 atctcgtcaa ataatggctg gcattctgac gagagatacc tagattcttc gaaattttct
    16501 cggcagtgac agaagacata ttccctgtta gtcgtatcag ctcatcaaaa actcgatctt
    16561 tagcgctctt tttcattttt tcctccagtt taatgtgtct aaaagcataa taaactatcg
    16621 gctgcaatat gtctattcta tatttgtatt ccaattttta ctttgaaaca caaatagtcg
    16681 aatatttgcc tcagatatct gacaaaataa tttatctacc aatttagttt ttatctaata
    16741 tgatttttat gttttttcat agctacaaat attgaactgg attcatatat tagttttatt
    16801 aatagattac agaagggtta agtatatttg catagtttcc aattacttta tccttctgta
    16861 actttttcaa tcttagattt actagcccgt ctcgggccct attttacaat ggttttgtcc
    16921 acttttctct ggtagaaaaa cgtggtagaa aaaataaaat aacacaaaaa aagcggcgtt
    16981 tcatccgctt ttggtagaag attggaaaac tcagatagaa aaaggacgat ttttagctct
    17041 ttagaacgtt gataagtccc cattcttact gagttttgcc attatctcct atacatcttg
    17101 aattctaaga ataggtcatt atagatgcct aggtatttcg atcctagatc tttgtagact
    17161 tcaagatggg agatcgtgtc atcagatgga tagaattgtt cgtccgacga aatgtctttt
    17221 ggcaataacg cttttgcttc ttcatttggt gtagaataac caatatactc tgcattttgt
    17281 gccgcatttt ccggttctag cataaagttg atgaaatcat aggcaccttc tttatttttc
    17341 acggtttttg gcataacgat attatcaaac caaagattgg atccttctgg tgggatcaca
    17401 taatgtaaat gttcattttc ccacatcata tcggcagctt cgccagaaaa tgtcactgcc
    17461 acggaggctt cttcattgat catatacatt ttgatctcat ctgccacgat tgctttgaca
    17521 tttggtgtta aatgattcaa tttatttgct gcttctgtca gctgtgccat attcttacta
    17581 ttcaaagaat agcctaaact attcaaagaa agccccataa cttctcgtgc accgtcaatc
    17641 agcatcaaac tgtcttttaa ttccggcttc cacaaatcat cccaatgctt aatttgattt
    17701 gcatcaaaga atttatcgtt atatacgatc cctaaagttc cccaaaaata tggaatcgaa
    17761 tactgattat ctggatcaaa atccaagtct aaaaatcgtg gatcaatatt atttaatcct
    17821 ttgatcttcg aatgatctaa tggaagtact agtttttctt tgatcatttt ttggatcata
    17881 tattcacttg gtatagcgat gtcgtagttt gtcccacctt gctggatttt tgtgaacatc
    17941 gcttcattag aatcaaatgt ttcataattc actttgtatc catattcttt ttcaaatttc
    18001 gtgatcaaac taggatcgat ataatctccc cagttataga tggtaagtac ctttgctcca
    18061 ctcatgccac ttgttttttc aagttgacga acaccaagca gcagcaccgc aataatgatg
    18121 agaataccta aaaacagaga ttgtaatttt ttcatcgcag ccgtgccacc ccctcgcgta
    18181 ctcttctgtt tttcttcagc cgttttggac ggttttcttt actaataaag tagtatccaa
    18241 tgaccaatat catggagaac aagaaaacta acgcacttag cgcattgatt tctaaactga
    18301 ttccttgtct tgcacgagaa tagatctcta ctgagagcgt cgtaaagcca tttcctgtga
    18361 cgaaaaatgt aaccgcaaaa tcatcaagag aataggtaaa tgccataaaa tatccagcta
    18421 tgattcctgg agaaagataa ggcaaaatga tatttttgac tacttggaaa ttattagcac
    18481 caaggtctct agccgcatcg accattgaat cgttcatttc ctgcaatttt ggcaagacca
    18541 tcaagacgac gattggaatg ctgaaagcaa tatgggaaag caatacactc tgaaaaccta
    18601 atccgaatcc tagtagtgta aagaaaatca agaaactagc accgataata acatcaggag
    18661 agactaataa gatgttattc atgctcaaca acgctgtccg tgcacgtcgt tttttcgtgt
    18721 aatagattcc catagcccca aatgtcccga tgatcgtggc gatcaatgca gataagaaag
    18781 ccagcatgaa cgtattcaat acgataatga tcaaacgtgt atcttcaaaa acagcttcat
    18841 aattttccca agtaaatcct gtaaagctgt tcatcgttcc tccttcattg aaggaataaa
    18901 aaatcagata gaagatcggt gcatataaga ataaaaagac gatccctaaa taaagatacg
    18961 accatttaaa ttttttcatt tatgagcgac ctcctttttt cttctcgcct gtcaggagca
    19021 tcacgatgaa catagcaatg attaaaatca caccgattgt agaacccatc ccccagtttt
    19081 gtgtaaccaa gaaatgctgt tcgatagccg ttcctaaagt gatcacccga tttccgccaa
    19141 tcagacgagt cagcatgaat aaagaaagag aaggaataaa tactgcttgg acaccacttt
    19201 tcacaccatt taatgataac ggaaaaatca ctcgtcggaa ggtctcaaag ctattcgcgc
    19261 ctaaatctct actagcactg atcaaagaag gattcatctc ttccaatgca ttgaaaattg
    19321 gcataatcat aaatggaatc tcgatatacg ttgccacgaa cagaaaactg aagtctgtga
    19381 ataatatctg tttcggcccg atcccgataa aatcaaagaa atgattcacg ctgccgtgca
    19441 cactgaaaat cccaataaat gcgtaagctt taagcagcag attcacccat gtaggcaaaa
    19501 taatcagcat cagccataat tgcttgtgct tcagttttgt taaaaaataa gcagtcgggt
    19561 aactgatgat cagcgtgaaa aacgtgatca aaaatgcata ccatacagaa ttgatcgtca
    19621 tagaaagcga tgtccccgac gtaaaataag atagataatt attcagcgtg aattgcccat
    19681 tcatatcaaa aaaagattga taaatgatca ttaatacagg cgcgatcacg aataaaccga
    19741 gccacaaaat ataagggacg gaatagatcc tgcgcattgt tttcattctt gtccccccta
    19801 ttcttcgtag ctgtcaagac gtgcatcgaa ttcttcttca gactcgttga aacgcatgac
    19861 atggatatct tctggctcaa aggccaatcc tactttgctt ccttctttag cttttttcgt
    19921 tgaatggacc atccattcat tttgctgttc atcataacag atgatttcat aatggacacc
    19981 acgaaacagc tgagtatcga ccgttacgac tagttttcct ttatctggtg tcgtgatcgt
    20041 caaatcctct gggcgtaaaa caacttcaac tggttcattt agacgcatcc cgccatcgac
    20101 acattcaaat tgcttaccaa caaactcaac tagattatct tcgatcatta caccgtccac
    20161 gatattgctc tccccaacaa aatcagcaac gaaatgattg attggctcat cataaatatc
    20221 tacgggtgta ccactttgga cgattttccc tttattcatg acaaaaatct catcactcat
    20281 tgccaacgct tcttcttggt catgagtaac aaaaataaac gtgattccta atcgttgttg
    20341 cagatcccgc agttcatact gcatatctgt acgtagtttc aaatcaagcg ccgataacgg
    20401 ttcatctaat agcaatactt tcggttcatt tacaattgct cgtgcaatcg ctacacgctg
    20461 tctttgacca ccagacattt cactaatctc ccgtttttcg tatccaggaa gctggaccat
    20521 acgcaaagca tcttttacct tcttttcgat atctgatttg gacattttct tgatcttcaa
    20581 tccaaaagca acgttatcaa aaacattcat atgaggaaaa agtgcataat cttggaagac
    20641 tgtatttact tgtcgcttat tagctggcaa atcattcaac cgtttccctt caaaatagat
    20701 gtccccttct gtagcttcgg tgaatccagc tataatacgt aggatcgttg ttttaccaca
    20761 gccggaagga ccaagcagtg tataaaattt tccttgttcg atctcaaaac ttactttttt
    20821 taatactgtt tcatcatcat agcgtttcac tacttgatca aatgaaatga ttggtttccc
    20881 cacgttttta ccccctatat tacaaatatg attgcgttgc aacaatcaat acttttgttc
    20941 gttttttgag atgattcctt aattgatgtt gttttgtcgc ttgataatag atcgactgtc
    21001 ctgcttttgc cacatagacc gtctctccta agcttaactc taattcccct tctaatacaa
    21061 aaataaacgt ttcagataat gaaggttcaa acgtcttata ttctcctgca ccttcaaaag
    21121 tcagcaagac aggctccatt tctttttcat tcgaatcagc cacgagccat tccaattcat
    21181 acccgttttc ttcatcgaaa taaaccgtat gatcttcttt tgaataaacc acttgcagat
    21241 tcgctgcttc ttgatgaaaa aattcttctg gagtcacacc taagacttca agaatagaaa
    21301 agaatgtttc cattgatggt gaacttaaat ctcgttccaa ctgggaaata tacccttttg
    21361 acaaatctgt gcgttcgcct agttcttctt gtgtcaaatt cttttggatg cgcaaatttc
    21421 ttaacttctc accaatttcc ataatttcct ccgaatcgaa gttttctaat agtaaacttc
    21481 ctgtttacta ccactcgtat tagtatacga aatttattga aaaaggcaac cctttgtaaa
    21541 attttttttg ctgaatattt ctttatcttt tggaataaat tctagttgtt tgattcttta
    21601 tttttcacct aatttttgtc taaatttacg gaagaacaag aataaaagag taggctttat
    21661 ggtatgataa aagaaaattt taaaaggagt gtctcacgaa tgaacgcttt tcgatctttt
    21721 caggtaataa aggaacctgt tttccataca gcaatcagtg atctgccatt tactgagttg
    21781 gctgaaaatg aagtcttggt aaaaattgcc tattctgatg tcaattataa agatgcattg
    21841 gcaatgagcg agtctggtca ggtgatacga acatatccga tgactccagg gattgattta
    21901 tccggaactg tcgtccaaag taacaatcca cgtttttcaa aagaagatct tgtacttgct
    21961 actggttttg ggcttggcgt cacccatcca ggcggttata gccaatatca aaaagtacca
    22021 ggagactggt tagttcctct accaaaaaat atgacgctgc gtcaagcgat gatccttggt
    22081 acagcagggt ttactgctat gttgtgtgtg aacgctttaa tccgtcaagg tatgacctcc
    22141 gataaaaaag ttgtcgttac tggtgcttct ggcggtgtag gcagtacagc gatagccctg
    22201 ttacataaac taggattcca gtcaatcatt gccttttcca gaaaagaaga gtctgtcaca
    22261 tggctaaaaa gtctaggtgc tttgcaagtc gtacgacctg atgaatttct gccagagaca
    22321 acaaaagctt taggaaaaca gcaaatcgac tatgtcatcg acacagtagg tggcgagcag
    22381 ctaagcagtc ttcttccatt gatctcttat aacggtgcag tagctttatg tggcaatgct
    22441 gggggaatca aactaaacgc gactgtcttg ccttttattc tgcgaaacat ccagttgatt
    22501 ggaattgatt ctgtcaatgt accaatagat caacgtcttt ctttatggca acagatggcg
    22561 gatttgcaga ttgcagatga actggtcgtc caagagatta ctctggatca attgcctgaa
    22621 acagcatcta aactacttgc tggaacacac caaggaagaa cactagtaaa tgtaggtgac
    22681 cataaatgaa gattctaatc acagctggag gaacgactga aaaaatcgat caagtacgtg
    22741 ctattacaaa tcattcgaca ggacgattag ggcaagcatt agctgattat ttagctgcca
    22801 atccggatac cacaatcgat tacgtgacta cgaaacaagc actgaaaccg aaaagacact
    22861 ccaatataac gatttatacg atcgaatctg cactggactt atttttacaa ttagaagaac
    22921 taacgaaaaa agaacactac gatgcgatta tccacagtat ggcagtcagt gattttactc
    22981 ctgcttttag tttttcagaa gaacagctgg caaaaaacct acccacttct tcaacgcaag
    23041 aagaactgga caattggttt gcggaaaatg aacagacaga taccactgtt tcaaagatct
    23101 cttctaacac cgagcatctt gtgctcgttt tgaagaaaac accaaaaatc atttcttatc
    23161 tacgtgaatg gcagccaaaa gcaaaaatca ttggtttcaa actattagta gatgtaccaa
    23221 aggaatctct tctggcagtc gcaaaaaata gtctgataaa taacaaaact gattttattt
    23281 tcgcaaatga tttgacggaa atccatggcg agacacacca cggctatctc ttatctaaag
    23341 atggaacagt ggaagaagct caaagtaaat ctgagattgc tgcattgatt actgagaaaa
    23401 ttagactgga ggaatcaaaa tgaaaaagat cttactaggc gttactggaa gtatttctgc
    23461 ttacaaaagc gctgatctta caagtcaatt cgtcaaatta ggtgcccagg tagatgtgat
    23521 tatgtctaaa agcagcacac attttatcac gccattaacc ttgcaatctc tgtcgaagcg
    23581 cgcagtccat acagacgtca tgcaagaatc aaatccgcag gtaatcaatc atatcgaact
    23641 agcaaaacaa gctgacttgt ttctcatcgc gcctgctaca gcaaacatta tcggcaagct
    23701 agcaaacggc attgcagacg atcttctttc aacagtcgca atggcgcttc cagtgggaac
    23761 accaaaattg attgcccctg ccatgaacac gaatatgtat caaaacccga tcactcagcg
    23821 taatctggaa acattgagat ctgtcggcta tcaggaaatt gaaccaagag aatctctttt
    23881 agcttgtgga gattttggaa aaggtgcctt agctgatatt cagacgatca tcgaacaggt
    23941 catgctgact cttaatgaaa gaaatgctta gaaaaaagga gtacttatga aaaatacaaa
    24001 aaactttaca ttaactgcga tgtttttagc tattttgatt ttattagctg ttacgccttt
    24061 aggttttatc cctatcggtc caatcaatgc aacaaccatg catattcctg taatcattgc
    24121 ttcgatcgtt ttaggaccaa gactaggtgc ttttcttggc ggtacatttg gactgatcag
    24181 catgatccgt agcacagtta tccaaacacc tttgtctttt gtcttttctc cgtttatccc
    24241 agtcatcgga acagaacatg gaagctggaa agccttgctg atcgcgttta ttcctcgcat
    24301 cttgattggg gtggttcctt atttcgttta taaaggtctg cgcaaactaa tgaaacaaaa
    24361 agcagattcc gtttctttat tcttagctgg actttccggt tcattgacca atacgatttt
    24421 agtgatgaat atgatctact ttttattcca gcaagattat gccaaagtca tcggaacaaa
    24481 tttaaatgct gtttattcag ctattctagc ggttattttt acaagtggta tacctgaagg
    24541 aatcgtcgca ggtcttgcga ctgcagcagt atgcaatgtc ttgttaagat acttcaagca
    24601 cccttctctt actaactgat agtcatcgta gccgatctct gatttttttc tcttttggtg
    24661 ttactattga atggaaagat ttgacgtcga aaggatgatc caaatgaaaa tttttgttgt
    24721 aggtgcaaac ggacaaattg gccgacacct gataaaagat ttagctccaa gttcccatga
    24781 aatttttgca ggggtgagag atgttgcttc ccaaacatta gtaaaaaaag agaatgtttc
    24841 gtatgtctct tttgatttaa cttggtccgt ggaaaaaatg accgaagcat tcaaaggcat
    24901 cgatgtattg atttttgctg ccggctctca aggaaagaat cttctgcaag tagacttgga
    24961 tggcgcaatc aaaacagtga tcgcagctga aaatgcgcat gtctctcgct atctgatggt
    25021 cagtgctgtt tatgcagatg aaccagcaaa atggcctgag tccatgacag attattatat
    25081 tactaaacat tatgcagatg aatggctgaa acgaactaac ttagattttg tcattcttca
    25141 accagtcaca ttgactaacg atgaagaagt tacttccatt caattaacta agcctaatga
    25201 gaaggcatca aaaacgatca ctcgctctac agttgctgct gtacttgccg ctctagtgga
    25261 agaaacggat atttctcgta cgactctagt actttctgaa ggtagcaaag agttgaatac
    25321 agcattccaa gaatgggcaa aggaggaata gatccatgcg tgccatttca atcaagcatc
    25381 ctggttctgt agatgtatta gaacaaattg aagtgcctgt tcctaaacca aaacaaggcg
    25441 aattactgat caaagtccat acagcagctg tcaatcgaac agatattatg aaaagagaat
    25501 cagtctcttt gaaacctccc taccctattt tgggagtcga agtagctgga gaggtagttg
    25561 agaataaaag tgatatctcc acttttactc ctgggacaaa agtatacgga ttagtcaatc
    25621 taggtggtta tgccgaatat gctgtgatgc ctgccgatcg tgcaatcctt ctccctgata
    25681 cgctagacta tgtttctgct gctggaatct cagaagtttt tttgactgct tatcaaacac
    25741 tttactagct tggaaaatta caagaaggcg aaactgtctt gatccatgca ggagcaagtg
    25801 gtgtgggaac agcagcgatc caattagcta gacagctttc tcacgcgaaa atcatcgtta
    25861 ctgcaggatc agaagaaaaa ctcgcctttt gtaaagaact tggtgcagat gaattgatca
    25921 actataaaaa acaagacttt caagaagagg tacgaaaaat cactgaaggt cggggagtcg
    25981 atgttatttt ggatttcatc ggcgcttctt actgggaaaa gaatttagct tctatagccg
    26041 ttgatggacg ttgggtcttg attggtatgc taggtgggac catcgtgcct gagatagacc
    26101 ttggtgtatt gattgggaaa cgtgtccaac tgcttggtac attattgaca cctagaagtg
    26161 atcagtataa agcagagctc gcacaaactt ttatgcaaaa agctgggcct tttctagaaa
    26221 atggcaagat tcggccaatc attgaccgta cattccaatt cagcgcagtc aaacaagcgc
    26281 atgaatatat ggaagcaaac aaaaacatcg gaaaaatcat tttgaagata actgaataaa
    26341 atcatgctga tcaaaaaaga ggctgggaca gaagcgttta actccaagaa ataagaagaa
    26401 attcacgaaa attgcttttc aaatttttgt gaatttcagc ttatttccga aggaatttct
    26461 tctgcttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt tacttttgtc
    26521 ccacgctctt tttccgaata aacggtgttc aaaagcttgc atctgcggta ataagtccaa
    26581 ccaagttaaa aacataagaa gctgttttta cttggctgtt cttattactt gatgcagggc
    26641 agctttttca caacctcttc actaaacagt gttcaatcag ctgaccctcg gtattagctc
    26701 aaaacgctga tttcacaacc tctttttatt tacgttctat ttcattcatt ttccgaagca
    26761 aatcgagctg cttgtatgcc cgcttgtcgc ccaaaaataa tgatctccgc aactgaattt
    26821 ccaccgatcc ggttgtttcc atgtaagcca cctgtgactt caccagcagc atataacccc
    26881 ctaattggct ggttttcttt atctaatact tcagtgttcg tattgatttt cacaccgccc
    26941 atcgtgtaat ggattcctgg tgcgattttg atcgcataat aattcggaga cgataagtca
    27001 tgttccatgg ctgtggcacg gttgaattga gcatcttttt tctccgcaac atccgtattc
    27061 catccatcaa ctgtttttgc tagtgtttct tttggtaaat cgattttttc tgctaattct
    27121 tccattgtct ttccagttgt gacatatcct ttttggtcat aaaattcaat agctgtggca
    27181 cgatcacgca cgccttggtc aaaaatcaaa taagctgatt tttcaggcaa tgctgtaatt
    27241 gctgcagata ctttatccct tgtatccatt tcattgacaa atcttttccc ctcttgatcg
    27301 accaagattg ctccttctcc gcgaacaacc tcaccaatca agaccccctc atcctgctgc
    27361 acagttggat gaatttgtat tttatccata tcaacggttt gtccacctaa tttttcaatc
    27421 atggtgatac catctccagt tgatccttct tgatttgtcg taatataatc agctaaatcg
    27481 ggacgatatt tttcaataaa ttctttgctg gcaccaaaac cgcctgtggt aactacgatt
    27541 gcttttccgg tgacctcttt tggttcttct ccttgaacat gtacagtcac ttcattgacc
    27601 gtttccccat ttttcttaat gtctgtcaca tctgcgttga caaaaatagg gatttcccgc
    27661 tcatggacgt tattcaataa cccctccact aagtatccac caatagccga gccatcagac
    27721 ggacgatgtg tcctcttttc actcatccct ccagtgatcg ttaagttgtc cagtttgata
    27781 ccgttttgat ctagccaatc gaccgcatca gcagagtgat cgacaaagta tcgaagcatt
    27841 tctttatcat tcgttcctcc accacctttt agcgtttctt catagaaggc atcattcgag
    27901 tctttgattc cttcttcttt ttgaaatttt gtttctgaag cattcatacc gcttgatgat
    27961 ttagatgtgt ttcctccggc aacaggcatc ttttccaaaa ttactggatt caacccagca
    28021 tcttttgctt cgatagctgc tgccatccct gcaccaccag ctccaataat cacgacatca
    28081 taagattctt tcatttcttt tggatctgta tatacttgtt cagaagcgcc tgatgatact
    28141 tcggcagatt ccttcgtact agaacttgtc tgcgctgtat ttttctgatc tgcgccgcat
    28201 gcgctcatag caagaagtgc aacggctgtt aataaaccag caactaattt tttcatttgt
    28261 atcccccttt tctccttata ctatattaag tgattttttt cacaatatca actctgtttt
    28321 tctttaagtc atatagcttt ggtaaacaca cgcttcttag tataattaag gatatacatg
    28381 aaggagttat tttatgaatc atttgaaaac cttttttacg aacagtacaa aaactgcagg
    28441 tagaatcaca aacggaatct atattttatt acgtatcatc gtcgttatta tgctagtgga
    28501 tcaggtctgg aaccaacact ggggaaatac aatgctttta ttactgacat taattttatt
    28561 tgaaatccct tattttctgg aaaagatatt aaagatacag attccaaata tgctagaaat
    28621 cattttgtta tcttttattt ttagttcaac agttttagga gagttaagtg atttttatgg
    28681 ctatttttca atgtgggata cttttctaca tgcattcagc ggatttttag ctgggggtgt
    28741 cggcttttcc cttgtttatt tgctcaataa aaatacaaaa accatgaact tgactccttt
    28801 attactagca gttgtttcct tctgtttttc gatgacagtt ggtgttatgt gggagtttgt
    28861 ggaattttca gcagataaat tactgcaatt cgatatgcaa aaagatacga tcatccagca
    28921 aatcaatagt gtggagttaa gtaaagacgg aaacactgtc tatcatgttc cagatatcac
    28981 tcggacaatc attgaaagtc aaaatgcaga tggtaaaaca gataaaacaa tcatccaaaa
    29041 tggttactta gacgtgggaa tcatggatac tatgaaggat ttatttgtta attttattgg
    29101 agcagttgtt ttcagtgtat ttggttacct ctatagtcga aacgattacc aaaaatttac
    29161 gttcatcaag aattttattc ctaaaaaaat caaacgataa aacatgctaa aaaacaagag
    29221 aaggggcagt gacaatactt ttgtcactgc cccttctttt ttgaatgtat ggcatgccat
    29281 tagttatccg atagtattaa ctcaaaaaag taagatatga ggaatgacta tttcgttttt
    29341 tatcccaata ctgaggactt atttcaccat ttcgttattt atctaattta cttaaaacct
    29401 gcataacttt ttcataatct ggattaggtg tgccgtctag attttcagca ataaaagtaa
    29461 aacccatttt tttataaaga gcaatcgcct gatggctcca tgtctgtgtg tgaagataga
    29521 ttggtccgtc cgtatggagg gtaggaaatt cttgcaagac tctggcagtc aatgcttttg
    29581 cgagcccttt tccttggtaa tctggtttca ctgctaacca atgaaaaacc ggatacactt
    29641 gctctcttga tttttttcgc caagcggtac aggttgctac tttttctcct ttttttgtct
    29701 ctacaaaaaa catccttctt tcaagttctt caggataagg agcaaagttt tgttgaaaat
    29761 actcaagtgc ttcatctgtc gtttgaaatt ccccaacgga agtctcaatc tccgcccaag
    29821 cagattcatc ttctttttga taaaatcgaa attcaaaacc ttccgctaaa ggcgtgattg
    29881 gaacattttg ttgaagtggt cttgtcatcc agatttctgc gtaaggtaac gttttatcta
    29941 acatttttct atccctcctc gtctccatta tgccaaataa catatgactc agctacttat
    30001 ttgactataa cagatagaga tataaatcag aaccagtcat ctgcgtcaaa ttcatttcga
    30061 ttagcgtata cccatgttcc tgccatacct cgcatgaaat ctcctaaagc agaagaagga
    30121 atacctccac caggtgcggg tgttcccgga ctaggaagtg gtacttgcgg ctgcagatgc
    30181 tcatcggtgg aatcaatagt tgacaagcgt tttttcttcg tttccttctg gtcatctgat
    30241 tccttctgat cttccgactg tttagcaaca aattcttttt ctgattgttg ttttatttta
    30301 ggctctaaaa tttcattttc caatccagaa acttgtgggg ccaaatgagc ttcttgcctt
    30361 atcgttttat tagattctga gatttttcta gatattcttg ctaactctag gcttcttgtt
    30421 tgttttactt tccctgttgg agaaactgca tgagccattt gttgtttttt ttctgacaag
    30481 ctttcttctt gtcttttttg ttctttttga tctatctgtt tgtttaatgg taaaacatgt
    30541 aatagtgact gagcatggag ttcttggagt gaatacgggt catgataact atacataatc
    30601 gtaaaatcac ctgtttgttt ggtcaaataa ccatcctcca atggtacttc attgattgta
    30661 accgatacat cctttaacgg tacgggttta cctaaggaat ttgttgctga ttggatcaac
    30721 tcttctttgt ttattttttc gtttggatga acaataagat catgaccttc taatgaacga
    30781 ttgtctggta tataaacata agtaaaggta atttcccctc ctgattgctt cctattattc
    30841 atcagttctg agtgaagtac ttcaaggatc tccgaccagt gactttttct gtctaatccg
    30901 tttgcttgca tccaatcaga aatagaagtg actttcccat tttgttcata agtcgataaa
    30961 tctatatttg gcactcgatc agaaaattca gcaggtaggc gcaaatcagg aatacgattt
    31021 acactactca tatgtgtttc tgcttgaagt tctttatttg tttgactatc tataaaatga
    31081 gtgatgacag tcgatgaagc agcagatgct tctacataaa ctacagctgt tgtttctgcc
    31141 acatttgatg ttttcgagtc tatataagtt aatacaacgg gatattctcc cggagttgta
    31201 gtatctactg tcccgttcat tttgatttct tctttatttc ctgaagttcc atcgcttttt
    31261 gttacatatt caacaagatc tttaggggcg taactctctc ctgttcttaa gtgaagatct
    31321 tttcctttga tagctgtttg atcagcacga acatggatca cagcagatgc agtcattgtt
    31381 tttaaagcaa ttggatcaaa ataggacaag gaaatagtag atgttcctgt attagtcgta
    31441 tccacgatat tcccattgtt tgaaattact ttggacatat ctccttgtgt tccatctgcg
    31501 ttcttcagcc tttctaccag atcagatatc gaaacttttg tccctgccag aacatcgatt
    31561 ttctttcttt caaactgtga ataatctttt tcatatacat aagaaacttg tgcgcttcca
    31621 ccgtccttta tatctgtcaa agcatgattc aaaatatcag tgatctgttt taactgatca
    31681 ccttttgtag gatcagtcat atcggaaaag atagaaagcg gcacactgct tccggtttcc
    31741 gatgtccata atgttttgtt aggaattaac cagtagtggt ttatcgttgg aggataactg
    31801 actttattat aggaagtcaa tgcaggaagt agctgttttc catttgcatc agtgaaagta
    31861 tgagtaatag tgatagggga atcagtggtc tcagaaacag aggtacgtac gaccttgatg
    31921 gtttgtgtcg ttgcctgaac gggtacatgc atatagacac ctacagataa actgatcagc
    31981 atcgtgcgca tcataaactt aacgtagtgt ttttcagaac acgaccgttc cttatctaaa
    32041 cgacaagcgt gtttatttag ttgttttgaa cgtctttttg aacacattta ttcttagtcc
    32101 tccctactct tgtctaaaca tgaagtagta attttcataa gatgatttca ttatataaat
    32161 aaaatcaaaa gaagatggac tattaggaga gtattttttt tgatttttta ttgtttcaag
    32221 aaaatcggaa taataactta tgtacttttt aattttgtta agtaatatat ctagttatat
    32281 ctagttatat ctagttacct tttctttgaa aaaaacataa atcagctaat aaatatgtga
    32341 gacaaagctg ccatccataa atactagctg attttttcag ttaaatgtct atttttttct
    32401 ctgatgatgg tatttccaaa atattcccag tcatctggag tcggtggatt tttccaaatt
    32461 atctgttctt tattaaattt ttcaagtaaa caatcagata aataaatatt cgtacgagaa
    32521 gtgattcgac tctcaatcac aatattgtaa tttttaaatc ctttcacttg agaaataatg
    32581 taatcggtat aagcagatcc ttgcgaaaaa tcaatacaga catgaatcgg tgcttcaaaa
    32641 tatgataccg gacaaatacc gaccaataaa aagagataat cataaaataa gcgaatcatg
    32701 aaacgttcat cttttcccaa gaaatagcgt ttattctctt gtatgacctt ttggattgct
    32761 gtactgaata ttggatacgt ctcgaagaaa aactgtagct gctttttaga cgtaaagcta
    32821 gtcatctcaa agtcgaatat ccaatttttt cgattgacat gcatcatacc catacgaagt
    32881 tcttttcgta tatatagtct ttcttcttca gagatttcaa tcgaaaatgg taattgatca
    32941 atcaattcca ctgacatttt ttgactaatc atgtggatat catgaaaatg agcttccgca
    33001 agtccaaatg cgccatctaa ttcaaattct tcttccgtga tcaaaaacaa catgatataa
    33061 gaaatctcat caatgatctg ctctttaggg atatgaagaa aagaaatatg tgataaatcc
    33121 ttgatgatct tcattccttc tgagctctta aagtattcat ctgaaaagaa acgttttccg
    33181 attggttgat tcccataggc cctcaacaaa ctaatagtgg ttagcaaatt gaatttgatt
    33241 cgttttgttg cagacagttt taaattgaac agatattcaa aatattgcac gatactcttt
    33301 gcttcattca tgacgctttc tctaaatggc atagaaaaac cattaaagac cccgaaatat
    33361 accccaaata atacgttccg tatgtttatt tcttccccaa ctaatatgtt tttctttaac
    33421 tttatttgat gctgttcaag aaaagagact aattctcttc tttttacata ggctcttgat
    33481 atgcttaaaa aatgattctc tgcaaatttt tcgatcgtta cttttgaatc cacgatctcc
    33541 gttaacagtc gagcaatttt tgatcgttga aagtagattc ttcttaaatt tttgatatcc
    33601 gtcaaattca gacgttcgac atggatctct gcttcttctg aaatttggat ctctggcttt
    33661 gttttgaatt cagtaaattc tttatttaat tctatgatat aatttcttgt tttaaattta
    33721 gacaaaccta atgtttcata taacttaggc agcactacat aattcttttt ctcaaattct
    33781 aaatatctag ctagcagcag tttttctcta tcttcctctt ctataaggta atccaacttc
    33841 atatcctaca cctcaaaaaa tgcctcatac caattacttg atatgcagat gaaagttcat
    33901 cttttcacct atactgattt tatgatggat tatgcttgtt ttttcatcag ttattctcat
    33961 tttttatctt ttttttgaga atattgcaaa aaatggaaaa atttatgagg aaatattcta
    34021 tattttttgt tttattgtgt taaaatgtac aagatttgcg ccatttgcgt aaacaaccac
    34081 aaaaaagagc aggacggcca ccgtcctgct cttttactta ttttaagttc cattacttat
    34141 taattggcta aacttctgct tgtttctgat attgcttgtt tttctccaat gatccgcact
    34201 tctgtttcta aagacacatc aaatttttct ttgattactt cttggatgtg cgcaatcaat
    34261 tcaatataat ctgtcgctgt cgcatgatcg atattgacga tgaatccagc atgtttttca
    34321 gagacttgtg caccgcccca tttcaggcct tgcaatcctg cttgttggat cagctgacct
    34381 gtatagtgtc ctactgggcg cttaaagaca cttccgcatg aagggtattc taatggctgt
    34441 tttgattgac gcaattcggt caactcatcc attcttgctt tgattgcttc ataatcccct
    34501 gtttgcaaac tgaatcgagc ttccaatacg atagcacgta attcttggac tttactgtga
    34561 cgataagaaa ataccatttc gtcttttgtc aaagttttca atgttccatc ttcaagcaaa
    34621 agatccactt cagcaaaaac atctttgatc tctccgccat acgcacctgc attcatataa
    34681 accgctccac cgacacttcc cgggatgccg caagcaaatt caaatccagt caatgattct
    34741 gccaaagctg cataagtcgt atcaatcagt gaggcacctg cttccgcaat gaccatcgtt
    34801 cctttgacat gaatctgttt catttcagtc agcatgatga ctacaccgcg aatcccgcca
    34861 tcttgaacga tcagattgct tgcatttcct aataccatcc aaggtatatc atggattcgg
    34921 caataatcga tgatttgctt tacttcttct tgttttttcg ggaatgcaag gacatcagct
    34981 ggtccacctg ttttcgtaaa cgtatagttc atcaatggtt catcaaacaa tatagtaatc
    35041 gtggctaagc tttcaactat ttcttcttta ttcactgagg attttccttt cttttctcaa
    35101 acgtcctcat tattctatca cgcttaatac aatcttgcca gtcttgttca aagttgatga
    35161 cggtagtgat ctttaagcac ttcctcacat aattcatgac ttcttacaac ttctttttgt
    35221 ttaagcaatt ctgtttccga tttacctaaa cggatctgag aaaagaaggc ctctaccatt
    35281 ggctcaaacc cgcgtttgac tagcgtgttt gtccagtcgc caaattcttt cacttttttt
    35341 ccatcagcat cttgaatgac aagctgggtc agatcgttta cttcataagt accattttta
    35401 cttgttactt gatatttttc tatattagcg ccacttgcta aatccatcgt taaaatagcc
    35461 gtttgatttt gtgtttctaa ttgtaaaatg gcatattcca aaaattcctt tgtttctctt
    35521 atctggtatt ttgttctcaa aatgggttca tctaataaat acacagctgt atcaataaga
    35581 tgtaaaaaca aatcataaag gacgaactct gtcgtttctt ttgccgctat tcgatttttt
    35641 tgcaggtgga tcaaccgctt atctgggata cgtttcaatt cttctaccat aggagcaaag
    35701 cgccggttga aaccgatcat caaaattatt tggttcttat cagctaattc ttgcaattca
    35761 cgaacttcat ttagatggac actcagtggt ttgtcaatat aaacatggat accattttct
    35821 agacattttt tggctaattc ataatgtact tttgttgctg cgtggatcat acatgcttcg
    35881 attttttctt ctaaaagctc atcgatcgtt tcatatagat gttggaaccc gtactctttt
    35941 tgaattcttt cttttgtttc tttatttctt gttgcaaaat aaaaatcaag tgttccttgt
    36001 tttttcgcat aagttggtaa atatgctttt tctgcgatat tccctacacc gattacacca
    36061 atcttcatct actttcctcc tggatcattt agttactttc atcttacacc attttttact
    36121 aaaatgaggt acaatagtat cgcaaaggta aggaaattaa ttcgaaggag tgtgctttta
    36181 ttgaaattta tctcttggaa cgtaaacggg cttcgtgcca tcgtaaataa aaatttttta
    36241 gaagtttttc atgagttaga cgccgatttt ttctgtctgc aggaaacgaa actccaagca
    36301 ggacaaattg atttagatct tccaggttat tatcaatatt ggaattacgc ggaacgaaaa
    36361 ggctattccg gcacagcgat ttttgctaaa aaaccagcat tgaatgccac ttacggaatg
    36421 ggtatcgata tccatgatac agaaggccgt ctgattactt tggaatattc cgatttcttt
    36481 cttgtaacct gttacacgcc aaattctcaa agcgaattaa aacgtttaga ttaccgatta
    36541 gaatgggaag aagcctttta taattatttg gaaaatctaa aaaaacaaaa accagtcatc
    36601 gtgtgtgggg atctaaatgt cgctcatcaa aagattgatt tgaaaaactg gaaaacgaat
    36661 caaaaaaatg ctggattcac tccagaagaa agagcggctc tttctcgact gttggataac
    36721 gggtttatcg atacattccg ttatttttat ccaacccagg aaggtgtcta ctcttggtgg
    36781 aactaccgat tcaattcaag gaaaaacaat gctggttggc ggatcgatta ctttttgacg
    36841 agcaaagatt tagagccagg actagctgat gcaaagatcc atacggacat tatgggcagt
    36901 gatcattgtc cagtagaatt agatttgaaa taaagaggtt gtgaaaaagt cgtttagttt
    36961 cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat tttgcataaa tttggcataa
    37021 taccgagaaa ctggcttttg aacactgttt atcgagagat tgtgaaaaag ctgtcctgca
    37081 tcaagtaata agaacagcca aacaaaaata gttcctcata tttttcgttt ggttgggctt
    37141 attaccgcag atacaagctt ttgaacaccg tttattaaga ggttgtgaaa aagctgcact
    37201 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atatttttcg tttggttggg
    37261 cttattaccg cagatgcaag cttttgaaca ccgtttatta agaggttgtg aaaaagctgc
    37321 actgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt tcgtttggtt
    37381 ggacttatta ccgcagatgc aagcttttga acaccgttta ttgagaagtt gtgaaatcag
    37441 cgtcctgacc tgagtattag agaaacaaat ggcaaaatag ttcctcatat tttgctattt
    37501 tttgagctaa taccgagggt cagctgattg aacaccgttt agtggagaag ttgtgaaaaa
    37561 gtcgcctact ttcgagtcgt aagaaatttt tttgaaaatg gttcctcaca actttgcata
    37621 aatttgactt aataccgaga agtcatgatc cccatctaac tccaaatcac aaggaatgag
    37681 ttcaaaaact agcttttctc aacaaatatt acataaaaaa ttctatgttt tttgttaaat
    37741 ttatttgctt ttttcaaaag tatgttacag taatttccca aggaggtttt acagaaatga
    37801 attttgttgc catggatttt gaaactgcca atcatcagcc ttatagtgct tgttctcttg
    37861 cgctagtcat ggtaaaaaat agccagatcg ttgatgaatt ctatacattg atacagcctg
    37921 agactccttt tttctggcga aatgtccaaa ttcacggaat ccatcaagaa gacgtacgca
    37981 atgcgccgaa attcccagaa gtctggcaaa ctatccaacc atattttcaa aaaaatcgtt
    38041 tagtcgttgc acataatgct gcttttgata caaaggtctt agcgggatgc ttagattatt
    38101 atcatcttga acagcctaat tatctttctt tatgtacagt gaaaagtagc cgtcgcctgt
    38161 ttcctgaatt tccaaatcat cgattgaaca ctgtgtgcga aaatttgaac atccaattag
    38221 atcatcacca tgatgcattg gaagatagtc gtgcatgtgc ggaaatcctg ctttatcaag
    38281 aaaaaaaatt cgggacagat ccattgaaaa aacttgtgac tataaagtaa aagaatactt
    38341 atgaaacaca caaagaggtc gtgagcctgc cgtttcactc cgagtcacaa ggagcaattt
    38401 caaaaaatag cttctcatgt ttattaaata ttgtgactgg tgaccgagga gctggcagga
    38461 gaacaccgtt tattggagag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
    38521 caaacaaaaa tagcttctca tatttttcat ttggttggac ttattaccgc agatgcaagc
    38581 ttttggacac cgtttaccaa gaggttgtga aatcagcgtt ttgacctgag tattagagaa
    38641 acaaacggca aaatagttcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
    38701 tgattgaaca ccgtttattc aaaaaaaatg gactgcgaca cgacttttgt cacagtccct
    38761 tcgtgtgttt ttctgccttc tcaaaaggat gacagtttct cactcttttc ctatttcttc
    38821 tattcaatca aataactcat tttatataca tctaaaaatt cacctagatc tgttcttgcc
    38881 cctctaggca tgaccgcttc gatttggaag cccatttttc ggtaaaggtg tacggctctt
    38941 tcattacgaa cttgaacgtc aagctccaat cgaaaaagta cacccatttc cttcgcccaa
    39001 ctgatgattt cttctagcat aagagtgcct agtcccattc cccaatattc ctgcagaata
    39061 ctgataccga cttctcccac gtgagacaaa cgaaattgac tgtctgcctt gacagatgct
    39121 gttccaataa tcgtcccttc atagattgca agcagcaata aattattatt gctttcgtat
    39181 atataatcca actcttcttc taaggtttct ggtggtaaca ggagttctgc ttcatccaaa
    39241 actaaaaatt ctgtctcctt attaacttgt cccatcatca aaagaatgtc ttttgcatct
    39301 cctggcactg cttcccgcaa gatgatccca acttcttcac tcatgatttt cagcccattt
    39361 ttctagaatt cgctgtttga aggtttcact ttgctccccg tatgagatta gtttcacata
    39421 ccgcttttct aaatctgtat cacttttttc taaaatcagt tccaaataat cctccggcag
    39481 tgcttcttct aatagatttc cccattcaac aacggaaagc ccatcacctt caaaatattc
    39541 atctaaccct aaatctgctc cgctagctgc tacccgataa atatccatat gatacaacgg
    39601 aatccgacct tgactatatt ctctaataat cgtgtatgtc ggacttttga tcatttgcgt
    39661 tatccctaat ccttgggcaa ttcctttcgt caacgttgtt ttacccgcac ctagatcacc
    39721 agtcaatatc agattgtcac ctggcattgc ggaatgacca attgcctctg cgaattgttc
    39781 tgtcattgtt aatcctgata gttcgatcat ttttcatctt ctcccgctct tctttctttt
    39841 tgccagtata tcgcgtaatg aagttttttt aaagaaaaaa tgaactagtc aagaacagca
    39901 gctgctgttt ttggctagtt cgcgtgtatt tgttaatcaa tcaatgtttg tgctgctgtg
    39961 ataatcgata atttatatac atcttcttca tttgctccac gagacaaatc agaaaccggt
    40021 ttgttcaagc cttgtagaat tggtccgatt gcttcaaagt taccgaaacg ctgagcaatt
    40081 ttatagccga tatttcctga ctgcaattct ggaaatacaa agactgttgc ttgaccagct
    40141 acttctgaat ctggcgcttt cagttgtgca actgaaggaa cataagaagc atcaaattgc
    40201 aattcgccgt cgatcatgta ttgtggcgct agttttttag cgattttagt tgcttcaact
    40261 actttgtcta cttctggcga tttcgctgag ccttttgtcg agaagctcat cattgctact
    40321 tttggttcga tatcgaacaa ttctgctgtt tttgcagaat ctacggcgat ttcagccaat
    40381 tcttgcgcag ttggattcac gttgatcgca caatccgaaa agacatattt ttcttgatct
    40441 cttccacgta ccatgatcat cgctccgctt gtccgactga tgccaggctt tgttttgatg
    40501 atctgaagtg ctgggcgaac agtgtcgcca gtcgaatgga tcgctccaga gaccattccg
    40561 tctgcaatcc ccatatacgt aagcatcgta ccaaagtaat tcacatcttt taaaatcttt
    40621 tctgcttgtt ctttggatgc ctttccattt ctacgttcaa caaaagtatc caccatttca
    40681 tcccacttat cgtaattatc agggctgatg atcgtaaagc tagatgtttt gattcctctg
    40741 gcatgcgctg catttcttat ttcttcttcg ttccctacta aaatgggttc cacaagttct
    40801 tctgctttca accgggcagc tgcgcctaaa atacgagcat cagtagcttc cgggaaaacg
    40861 attttgatcc cacggcgaac aattttaaat cttaaactat caaacaattc cacaagatga
    40921 cctccagacg tttttatatg tattatcata cactattcca gaaaaaaaga acagtttatt
    40981 ttatctgtat cagtcaaaaa tgctggaaaa attaagtttt tcacatacaa agcgaactgc
    41041 actataacag gaaagcgctg ttttattaca ctgtttcagg cagttgccaa tcaatcggtt
    41101 cttctcctaa cgcaaggagc gcatcattcg ttttcgagaa gggtttggaa ccaaaaaagc
    41161 cacgacttgc agataacgga ctgggatgtg gagatgttat gatgatatgg cgactcttat
    41221 cgatcatttt gattttttct tgtgccggtt ttccccacaa gataaacacg attggttttt
    41281 cccgttcatt taatttttca atgatcgtgt ctgttaatct ttcccaacct ttcccgcgat
    41341 gagaatacgc ttgcccttcc cgaacggtaa gaacggtgtt gagtaaaagg actccctgtt
    41401 tagcccatga cactagattt ccatgttgaa caggtgcgat tccaagatca tcataaagct
    41461 ctttatagat atttcttaac gatggcggga tctttacgcc aggttgcaca gaaaaagata
    41521 agccatgagc ttgattttct ccatgataag gatcttgtcc taaaatcacc actttaactt
    41581 cttcataagg agtcaattcc aatgcttcat agatatgata catatctgga tggatctttt
    41641 gggacgcata ttcttttttt aaaaattctc ttagatgcag ataataatct tttgaaaatt
    41701 ctgaggacaa aacttcttgc caactgttat gaatgatttc tttcaaaaac tccacctcct
    41761 aataaaaaga ataactcaca ttttcttcaa tcacaaggga caatcttcac cctcagcact
    41821 tgattaatat ggtaaactag gaacaagaag cagaaaggaa cgataatcat tatgatcaaa
    41881 ttaattgcat cagatatgga cggcacatta ttagatgccc atatgagtgt ttctcctgaa
    41941 aatgccgagg cgatacgttt tgcaaatgat gccggtgttg agttcatggt cgctactggt
    42001 cgaaactatc aagaagctcg cgcagcttta gatgaggtag gaatcgattg tgcgatgatc
    42061 actttgaacg gggcacaggt atttgataaa gaaggaaatt cattgtttac cgtgtcgatt
    42121 ccaaataatc aagcaatctc tgttttagat attctagatg ctaacggtat ttactatgaa
    42181 gtagcaacca acgatggtct ttattctgaa aatcaagcga aacgaattga aagttttgct
    42241 tccatggtgg ctacccattt acctcacctt acgtataaaa tggcgattgc catggcctca
    42301 gctaagctgg agttattgca catcacatac gtggacagta ttcgtgctat tttggaagaa
    42361 aagaatctgg aagttttaaa aattatttgt tttcatacag aagggccagc tgtattaggt
    42421 ccagttggaa agcagatttc tcttttaggc gatctagccg ttacttcctc tggtcaaaac
    42481 aatatcgaag tgaaccataa aaacgctcaa aaaggaattg ctgttgccca tgtcgctcac
    42541 gagcgtggga tttctttaga agaagtcatg acgattggcg ataacttcaa tgatgtcagc
    42601 atgctgcaag tagcaggagt cagtttcgca atgggaaatg cagaaatcga agtaaaagat
    42661 tatgccaaat atacaacgga cacaaacctt gaatctggcg taggaaaagc catattgcgc
    42721 gcgattgcag aagacttgta gttttatcta gaaaagaggg atatagatgt cagaattttt
    42781 cattcaggaa aagcagcttg gacgtgcaac tcggacaatt gtcaaaaacg aaaaaggaca
    42841 ttccctgttt ttgatggttg gtcgctgggg aacaaagggc gatgcattgt ctctttatgc
    42901 catgaatggc gatctcgttg ctcacatcaa gcagataagc ctgacattcg gtacgcgttt
    42961 tgagctgtat aaagagttcg aaaaggtggg aaccatgcag aaaatattca attggcccgg
    43021 tgacttttat tatattcgta gacttcactg gacagtccaa ggtgatatct ataatcatca
    43081 atatcaaatc catcatttca atcagcaaat catgaaaatg gataaagcaa cacttttttc
    43141 aggagattac tatgtattgg atgtctcaaa tgatgaagat gctccagttt gtatttgtat
    43201 tgctgcggtt ttagattact ggctctaccg taaagacaaa agtcgcgata agcctgtttc
    43261 ttaccgactt aacttaagtt aaaaagatgt acctgaaatg cggaaatacg catttcaggt
    43321 acatcttttt agatattctt ttgcatatga tcataaagat gaccactgat catccgctga
    43381 ccgacaactt tgaagtcatg gcgttcgtat aattttttag cctttggatt tttttcatcc
    43441 acacttagac cgatgacgga gcgattagct ttcttcgcca atttaggtaa tgcttctaat
    43501 aatcgcgaac cgatgccttg tcctctaaaa tcttctgata cactgataga gtccaaatac
    43561 cattcgttgg gaaacgtttc tttatcaatg aacaaacgtg tagacgcatc tagctgatat
    43621 ttctctaaga taggtaccag tggctgatcg atgattgatt cttcttcatc tgtataaccg
    43681 taagcaactc ctgcaacttt accgtctatt tcttctacga tacctcgtga ataactgtaa
    43741 cgataatttg gatcagtgat tgcttcttct aaaatctcta aagtcttttg ttcccctgtc
    43801 tgcttcaaaa atggcagttc catatctttt agaatcacta agatcaatgg ggcgatttct
    43861 ggagcatctt cttttctcgc aaaacgaatc atagtttcct ctccttttct ccattctaac
    43921 atgcagaaaa agaaatcgca aaatcgttat tttaaaaaat cttcaatctt ttcagtaatg
    43981 aaataaccat gagtaacgat tcttgccgct tcagttcggc aataagggca gacgactggc
    44041 atttctttat cattatgttc gactacatta ttgacttctt cgtatgcaaa tttttttccg
    44101 caattagggc atttcatttt ttccatgtta tctcaacttc ctttcatctt tactctctta
    44161 gcttactctt atattgtaaa aaagagaagc aatatccttc ttctatgcag atatccatac
    44221 ctgacggtcc tgttctccat ctattaatcg gactttataa taaggacgtt catctttgac
    44281 tagaagtgtc cactctttca cttttgcttt tttcccgtag tagctgactg cttccttcat
    44341 cgctgcttgc ggttgtttga actcttccgt tttttctata tcaaaaagat gttctgcggc
    44401 cttttccgtg tcatttcgta cggttgtttt cccagtggat ggattgactg ctatgacttg
    44461 tccttcacaa aaaaactggt attcatatgt tgcattcgta ggattctcca aatctttttc
    44521 aactgcaaaa tgaatagcag atatgttatg ttcttttgtt tcgtttttta cgattgctgc
    44581 tgcttttttc aatgagatcc gatattcctg gtcactaata tcatccatgt gaaaagcggc
    44641 attgagcagt cccgtcatac cggtaatccc tattacgatg agggcagcaa caccaaacat
    44701 catttttttc attcttcatt ctcctgtttc ttttttttaa agaatatcaa gaaatgaacg
    44761 aatgaaaaat cgaatgaaac gaaaaaaaag tgacaatttt gttatcttta ttcgtgcagt
    44821 tctaatggca atccgtctgg atcaaagaaa aacgtcattt tttttcctgt aaaggtatct
    44881 tctctaatcg gttctgattc gatccctaag gactgcaatt ctgcaattgt ttcttcaata
    44941 tcgtctactt tgaaagcaag atgacgcaag ccacaagctt ctggatagtt tggtcgttgt
    45001 ggcgcattag caattccaaa aatctccaat tcagcacttc ctagtttcag atctaattta
    45061 tagtcatctc gttctttgcg gtaattttct ctgattactt caaatcctaa tttattaaca
    45121 taaaaatcac gtgatttctg ataatctgaa acaatgatgg ctatatgatg gatcgttgta
    45181 aggttcatat gagcactcct attcttcgtt taagctcgga tctatattaa tctccagttc
    45241 cattgtaaat gtgtcagatt gaaaaaaata gctgtttttc ctttttataa gaaaaaaggc
    45301 aaaaaaaaca gaaagtaggt cctccaagac actcttcctg ttcccaatat aataaatgaa
    45361 agtaagaaat tatattttca agaaaacaaa cagaaaatta tcataacaca aattatttat
    45421 aattgaaaga ctagtttttt ttcaagaaaa gcatacaata gattgtgtta gtaaatacag
    45481 aacacactac atttagtgtc ttaaggagtc ctcatacatg aagtcatatt ttcagttttt
    45541 agctcatcag ctaaaaggct ggccgcaaca aaattattat cttttctttt tcagtcttgg
    45601 ctgccaggtc atgactcttg tcaatagtcc catcacttgg ctgtccgtta ttacatttat
    45661 cggtaccacg cttggtgtat tgtgtatttt atccatcaat gcggcaaaat cagtcaacgg
    45721 tattttaggt attttgtctg cgatttgttt tattatcgtt gggttttcag caaagaacta
    45781 tttaagtatc ggtgaacaga ttgcttatat gatcacattg gatatccccg tattgttaag
    45841 taaagaatgg aatcataata tggcttcaaa aatccgaaaa ttcactggaa aaagctggtt
    45901 tatcgcaatc atcagtactt tccttgtcta tcttgtttca ggattcctga ttggtcgtta
    45961 tacagatgat cctcggccgt gggtagatgc cattgctttt tctattagct tgactgctgg
    46021 tatcatcagt ttcttgcgtt acaacaacca atattactgg tggttagctt cagggcttgc
    46081 tcaaatggtc ctttggtata tttcatttac gcatggatct gcaagtttgg cgatgttcgt
    46141 gaacagctct gtttacttgc tgaatgatgt ccttgcattt accgtttcac cttggtataa
    46201 ccaaaaagaa cgtgaacgta tgcaaaaaat ggaagaagaa tactacaacg cacaacaaca
    46261 cgcataaaaa aactgagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac
    46321 acgtataaac ggcggaatca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat
    46381 ttgaaaagca attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag
    46441 cctctatttt ttatagtaat tccttcagat actttcttgc ctcatcattg aaacgcagtg
    46501 attcttctaa cttctgataa tattccaacg cttgtttctg agcttcagta aaacgataat
    46561 gttttccttt ccatttgtcg attgtctctt gcacatttcc agattggata tctttcacta
    46621 ctagttgcca tttttctttt gagactgtac ggtctttctt atcagcagat tgtatagctt
    46681 ctcgttcttt acgcaatact tttaaaaaac catttctgac tatccgagga atgctgtcga
    46741 agaacccttc tgtaaaacca tagtgacaat attgcttcca aataaataga tagatttttg
    46801 gttggatgaa tcgttggttt ttcgcaaaat attccatctg agcagtgact tctggtgttc
    46861 gttgacgttt tgtctttctc aacacggaaa taaatgtttc aaaataagca ttaggatgta
    46921 ctggcacttc ttcatatacg atggattgcc aatctttacg taaaaatgcg cgatagttga
    46981 tcaagaattc ttctacatcc tttactaatt cttctgcaaa gtcgtcaaat agttcttttt
    47041 ttatctgtcg cttttttgac tgcccattga tgtgttcact tattttcttg atttcatttt
    47101 ccaatgcttg ataatccgct atgtaaatcg gcatttctac ttggcgaaat tctgcgagcc
    47161 gctgagctaa ttttatatcc ggtaaatatg gctgtttcat ccgacgattt tggtacaaga
    47221 caaaacagta tttttgccat agtccttcag gaaaatcgat attcttctgc ttaagccata
    47281 ataattcgtc taaggccaga tcaacttttg tcattccctg atggatcgaa gctgccactg
    47341 tcggagagac atgcaggtga tcggcaaagt ggttgatgcc tagttttagg atctttccgg
    47401 tttttggcga tttaacgatg tattgcactt ttaattctct accacactca caatacaatt
    47461 tttgctggct tcgttttgtt cgaaaaaacg gattgatctt gaagtcagaa aacacccaat
    47521 ctgttgcagc taaataatgt tcttccataa aacgagagct gattagatat cggcggtgct
    47581 tatcgactag ttcccgctgt tttttcgtta attttgcata gatctcccaa cgttgactgc
    47641 ttgtgtattg tttagaaatt ttgatgggat agcttttgct gatttctttt ggaaaccatt
    47701 cttcaaagac ggattgccat tcttccacgg ctgtttcttt cctttctaat tacaaaaagc
    47761 tggctactaa cataacgtta gcaaccagcc agtgtttctt gctaaattag tgagttgttc
    47821 cggcatttcc ggaaatatct tctttatttt ctactgctgc ttcaactgca taagtcaaag
    47881 aagaagcaat gtcttctaaa gacatagaag gcgtacccac tggacgatcg atcacttgat
    47941 cgggtgagaa tggcacgtgg atgaacccac ctcgaattgc cgggaattgt gtttcgatca
    48001 aatgaagcaa acgatacatg atatcattgc agacaaatgt tcctgctgta taagagatgt
    48061 acgctggtag accatgatct tgtacatttt ttgtcattgc tttgattggc aatgaggtaa
    48121 agtaagcggc tggaccgttt tcttctaaag ccgtatcgaa tggctgattt ccttcattat
    48181 cagggattct tgcttctgct agattgattg cgacacgttc gaacgagact gctgaccgcc
    48241 cacctgcttg tccgacacag atcacgacat ctggttggtg ctgttggatg gcttctttga
    48301 ctacttgact gcttttttcg aatacggtcg gtacttccac tttgatgatt tcagcaccgc
    48361 tgatttcatc tggcattttt tttactgctt cataggctgg attcactttg tccccaccaa
    48421 atggatcaaa acctgttact agtactttca tctgttgttc ctccgtccga ttgatttaac
    48481 atatggttat cttttatcat accattttcc ttgaacagcg taaataaagg aaacaatagt
    48541 ttaaataaca taacagatca aacttaatat attcttataa aaaaatagtg ttccactaca
    48601 atgttagaag aggttgcgac aattattctg tcacaacccc tctcttctat tatttaaata
    48661 gaatcatata agcaatttgg aaaactagca taaataacgc aataaacaac tggtttttga
    48721 tcactccgta tttgtctttc atctccagca tcgctacagg cacgatattg aagttagcag
    48781 ccatcggtgt cagcagggtc ccacaaaaac cgcaagtcaa tgcaaccatt cctattaacg
    48841 ctggattcgc tccatgacta aatacgaatg gtgcaccgat cccaaccgtc atcacggtga
    48901 tggccgcaaa tgcattcccc atgattaccg taaatatcac catgccaaga gcgtaaatga
    48961 tgatgccgat gttcacattt ccttctggaa cgatcgtacc tactgcattg gaaatcactg
    49021 tcccaactcc agcgcttgta aataccgcac ctagagaagc taaaagcatt ggcaacatgc
    49081 ttaacggccc tactgtgccc agcatatctg ctgcatcatc taaaaatgta cttggtcgat
    49141 tatctcgaga aaagaacatc aagattagca tggctgcaaa aacaccgacg cccacgccga
    49201 ctaaagcacc taaattggta aatagagcaa acaagatcgc aaagacaccg atactcaaag
    49261 ctggaataaa aattttcatt cctagtttgt ctgacatttt ttccatatat tcttttgatg
    49321 gaagccggct ttctcctttg ctgactttct tagcaattgc tggtatggtc atcgcaaaga
    49381 tcaagccacc gttcacgatt gccggaagcc atcttcctcc tgcaataact acccctaaga
    49441 ccgtccagaa aaaggctgac ccataacgat gaggattggt tttatctgtt aaatttctta
    49501 ctccagtgta aatcaatacg agtcccatca cgatataaag gatctccagt aatttatcgc
    49561 ctaataaaat atcaggattt gtaaaaaagt ccatcttatt gcccctttcc tggataatat
    49621 ttcttcgcta atttcttttc tttaagatag aagtagacac ttgccacaac taaagccgtg
    49681 atagccactg gaacttccac taaagcaagc tgtcccaatg ttacgtcata tcctagatct
    49741 ttcagtgttg attggactag caacgcccct gctcctccga tgaatagtac ttggccaaag
    49801 aaccagcaga cattttccat agctgaagcc atacctttta gttcttcttc atgcttagga
    49861 tggacttcta acccttttga ttcgatggtc cccaatgcca tcggtaaaat gattggacga
    49921 acaaatccag caactccacc aaaactcacg ttaaaagccg caaagatcat tcgaaagatc
    49981 ccataaatat ctacaatcat accagcagat actttcttga atcgcttgat caaggaagcc
    50041 gctgattctt tcagaccatt tctttcaagc gttcctgttg ccaacataat gatgataaaa
    50101 atcgccatcc cgcgattgtt tacaaaactt gtacctaaaa gttctaacat tccttgaatg
    50161 ccaagaccgc cagtcaaagc tgtaacaact aaagcaacca ttacgatcaa tatcgagtct
    50221 aatttaaatg caaacccgag aataacaatc aagacgccta aaaggctaag ataattttcc
    50281 atatattttc ctccataaaa tgacaatatt tttttaatta taaagcaaaa cacataaaaa
    50341 atatagttgt tttctcacga aatagacact atttttaaat atttttcgtt atttttttat
    50401 cacaaaaatt atcttactta ttgtaaggta aagctttttt taatttattg cccgataata
    50461 tatagaaata aggtctagtt actgtttttt ttaaatgatt aataaataac aacttctttc
    50521 tatgaaattg caaagcattc atcttctttt ccgctaacga tatatccgtc agtgcttggt
    50581 acactttact aaaaagtatg agattgccga tatctggata ggtgtgctat actacagaaa
    50641 aagatataca atctgccacc gggtaggata aagaggatga tcattccatt aggtctttga
    50701 agggatgatt ttcctctttt tgtgtatttt tttatagtta aggaggaatg taagtatggc
    50761 atggatggaa ttaatcatag caggaatttt ggaagtattc tggtcaacga tgatgaaatg
    50821 gagtgatggt ttttctaaaa tcaattattc tttttacaca gtgattggca tgattgctag
    50881 tttttacttt ttgtcaaagg caatcaaaag tttgccgatg agtctctctt atcctatctg
    50941 gacagggatt ggcgcagttg gttcggtcat aattggtgtg gtcttgtttc atgataagct
    51001 gaatctttcc acttggttct ttgtggggat gctactcatc agtatcattg gcatcaagat
    51061 tactagcggc cactagacac ttggaataag tactgatcag aaaaaataag cctttttatt
    51121 taatattcaa tttttttatg aaaaaataag aaataagtcc aatgacctag cgacttctcc
    51181 actcatcagg tgtatgcttg tactatctat agaaaaggag tgaatatttt tgaaaagtct
    51241 ttcggtccaa gaattatcca agaactttgg tcacaaacaa gccctcagcg atgtcagttt
    51301 tagcttatcc cctggcaaaa tcgttggatt agtaggtcct aatggcgctg gaaaaacaac
    51361 gatcatgaaa gctattttag gactgatcca ttactcagat ggaacaatct gtattggtga
    51421 aaatgagatt tctccctcta gtcataaagg gttggaacaa gtaggagcat tgatcgaata
    51481 cccgggtatc tatccattct taacaggcta tgatcatctg aagttattct ctgaaaccaa
    51541 cgatgtatct gctatcgaca ctatcgtgaa tcagctcaag atggaaaagt acattcacaa
    51601 aaaagcgaaa tcctactcgt tgggaatgaa acaaaaattg ggaattgctc ttgccttact
    51661 gaaccatccg tctatcgtta ttttagatga gccgatgaac ggtttggatc cacaagcaac
    51721 aagagatgtg cgaaaaatca ttaccgactt ggctactcag ggcacctctt tcttgatctc
    51781 cagtcactta ctcagcgagc ttgaaaaaat ggtcgatgag ctgatcctga tcaatcaagg
    51841 aaagatcatc aaacaatgta caatggctga attgaaccaa acagcgcaag atttcatcgt
    51901 tatctctaca acaaatgatc tagctgctcg aacgatcttg acagaagctg gatatacttt
    51961 ggaagatcct gataaaatca agcttttaaa agaaaacgaa gaattattag gaaccgtgat
    52021 ccagctattg tctgcacaaa atatccatgt gacagacgtc cagcatctga cgaatgattt
    52081 ggaatcttct ctattggaaa ttctggattc agtaaagggg gaagaagaaa aatgacattg
    52141 cttgtaaaac aagaattatt taaattgatc aagaaaaagt caactgctgt tttatctgtt
    52201 ctattagttg ttttgctcat aggaacagca cttctagcca aaaaatacac gacgatcatt
    52261 gatccagttg aaatgactgc tcagcttttt agtgccacat cttggattgt ctttatcatg
    52321 attgcagctg caagcacgat catttcgatg gaagcacaat atggtacatt gaaaaatctc
    52381 ctttatcgaa agtattctcg aggagaaata ttagtaagca aatggatcac attagttatt
    52441 tattctgttt atttatacct tttagctatt attgtcactg tgttgatgaa actgattctt
    52501 ttcccttcga tttccttcac ggagaaggtt tctactggtc aaacactgat ccaaagcttg
    52561 ttcacttata ctttgggtag ttatatcggt ttatggctga ttttaagttt agtgttgatg
    52621 attgcttgct ttatcaatag ttccggcgca tccatctcag caggaatcgt cttttatttt
    52681 gcttcgtcaa tcatatctgg tatccttatt gcactcatcc aaaaatggga gtggatcaaa
    52741 tggaatccga tcagtatgtt gaatctgcaa aaccaaattg gaaacgaaga gatcatgaag
    52801 caattgactc atctttctac taatcaaatg ctattcggta atttagctta catcgttttg
    52861 ttcttagcat taggatatct cgtatttaag cgaaaaaatg tatgatgact catcaaaaaa
    52921 gaggctgtga aagagacgtt cagccttatt gccgattggc tgtctcttaa acaccgttta
    52981 ttctgaaaaa ggagctgtga caacatttgt gtcacagctc ctttcctagt atgtttttga
    53041 ataaacgaca ggctcacaac ctctctttat acttctttta tacttctata cgtgaagcat
    53101 cccagtggca aataaaacca ttgcaatcac tccgaccatc gtcacaccta taagtaaaat
    53161 cttatctaag tggatatgtt gtacaggctc gttttgctcc ttacgtgctt tgaggtaaaa
    53221 ataaatgcct ggcaagaaaa gaacaagaac aagcattact tcattaaagg ctacgactag
    53281 catagcccat acttgaaagg cacttgctaa aagccctact aaaaattgga cccattcttt
    53341 ccgctgataa gaaagtttca tttggtacaa tcctaagaaa agccacgtga agaaaatagc
    53401 tgctgtacca agtgtgtaag caaagttata agcactgtca gtgaataata atgaaagtaa
    53461 aaagacattc gtacataacg tcgtcaatac gatagcataa gttggtgccc catttttgtt
    53521 gagttttccc catgctttag gcaaaagtcc gtcttcagcc atgtttccca ttgtttcaat
    53581 cggtaagatc gtccatgaga gccaaacacc aactaaagaa atgatcaaac cgccgttgat
    53641 cacgactgct ccccatttac caaccatcat ttcaaacaca tagcccatag caggctgcgc
    53701 cttgatcgtt tgcagctgat tcatcgtcat tgtcccatat ggaagcatgg aaaccaagac
    53761 gtaaataata atcaagccga atatccctag aatcgttgct ttcccaacat ctgattgttt
    53821 ttttgctcgt gaacctacga cagaggctcc ttcaatacca acaaataccc aaagcatcac
    53881 catgatgcaa ctcaatactt gactggaaaa cgggatcggc tgtccattcg cattcaatat
    53941 aatgtcgcta gaaaagttat caatgaattg ttggatcgaa aacgtgctga tagctactac
    54001 aataaataaa aataatggca ctaatttaca gaatgtgacg atagcattga cgaaactagc
    54061 attttcgact ccccgattca ctagccatgc atatccccat aaaaagactg tactcatcac
    54121 gatcgatgcc agattttgcc caccttcaaa tactgggaag aaatatccta atgcgctcat
    54181 caacaatgtt gcaaaagcta cgttgcctaa ccagcatgtg agccagtaac cccaaccgct
    54241 gataaaacca gcgaaacggc caaaaccttc ttctgcgtaa ctaaagatcc cgccttttaa
    54301 atctggacgt tttttattga tattattgat cgacaaggag agcatcaaca ttgctgttcc
    54361 tacgagtacc caactgaaaa tagctgggcc gccagccgat ccggagatgt ccgtcataat
    54421 accaaatacg ccacctccaa tcgctgaacc aattactaag gcagcaagtg gaattaaacc
    54481 aattcctttt ttctgttgct ctgtatccat gtaagcatcc tccaaaataa aaccgctttt
    54541 atcaaaaagt ataacaaacc ttttttattt ttacttaatt aataaaaact ttaatagaaa
    54601 tataattcta ccggcttttt tctcattata caagcaaagc gcctagtccc tttccaaatt
    54661 acaccaccaa aaaacttaaa aaagatgcta tactaaaagg aaagaattgg aggatgatcc
    54721 atgaacattt tatatatatc gatttcagga aatacgcgtg cctttgccaa acatctagca
    54781 gaatatgctg aaaaaatgca tgcagaagat cctgtcaatc ctgaagttac tttaaaagaa
    54841 atccatgaaa atagtgattt tacgaaagaa acagaaccat tttttacttt cgttcctact
    54901 tatttagacg gcggaaatgg tttagataac ggtgatacag aaatcttgac cgaaacgatg
    54961 cgtgaatatc tggaacatga agacaatcat aaactttgtc ttggtgtagt cggtagcgga
    55021 aataaaaact tcaataatca gtattgtcta acagccaaac aatatgcaca aacatttggc
    55081 tttcctttct tggcagatta tgaattacgg ggaacaccat ctgatgtgac acgaatttat
    55141 cagattttag cagaaaacaa taaataataa aaaagaagaa gctgaaaaat agatttcagt
    55201 ttcttctttc gtttctattg tttctatcat attaagcttt gacatccatc acaggtgctt
    55261 ttgcttttgc tttacctgtt ttttccaaga caaagttttt tacacgatcc atattggtta
    55321 ccaagacgat catggatgtt tctttgcctg ctgctttgat cgcttctaag tcagcttctg
    55381 ctacaagcgt atcaggtgtc acttgctgcc cttctgttac tttcacatca aatggcgtac
    55441 cgcctaagtc aactgtgttg attcccatat gaagcaagat ttctaaacca tttggcgttg
    55501 tgatcccaat agcgtgtttc gttgggaaga cagagctgac taccccagta actggagaat
    55561 agatatgtcc gttttctggt tctacaaagt agccttcacc catcatcttt tgtgcaaaaa
    55621 ctggatcact tgctttatct aaagaaacaa ctgttccgtc agcaactgat gagaggatag
    55681 tcacactttc agctgaagtt tgaggtacta ctttttcagg cacttcattt actgtggctg
    55741 tttcagtcgc taattcttct ttttctaaac ggtctttagg aataccgaag aagaatgtag
    55801 caacgaagcc accagcataa gctgccaata atccaaggat gtagcctaac catttaccgt
    55861 cagagatcaa tgggatcaaa gcggctcctg aaggtccaat agcgatagcc ccgacatttc
    55921 cgatcattcc gatcactgcc ccgccgatac ctccaccgat acaagcagta ataaatgggc
    55981 gtcctagagg taatgttact ccgtaaatca atggttcgcc gattcctagg atcccgactg
    56041 gtaaagctcc tttgatcatt tctgttaatt ctttatcttt tttgcagcga atccataatg
    56101 ccaatgctgc acccacttgt cctgcaccag ccatcgcaag aattggaagc aatagcgtac
    56161 gaccagtttc atcaatcatt tgcacatgga ttggagtcaa aatttgatgc agtccgaaca
    56221 taaccatcgg caagaataat gtgcctagaa cgaagccggc aaatgctcca ccaacgccaa
    56281 gtacccagtt gatcccaccg accatgccat cagaaatgaa acctgctaaa ggcatgatga
    56341 agaaaatttc aatcagaccg atggcaatca acgaaagagt tggtgtaacg atgatatcta
    56401 ccgcatcagg tactacttta tgcagttttt tctcaacgat tgacaatagc caaacagcga
    56461 agatgacacc taggatccca ccttgtccag ctgcaagagc ttcaccagta aataagtttt
    56521 tcagtggtgc ttccggattc atccctgtca gcatcacaac ggccccgata actccaccaa
    56581 gagttggtgt tgcaccaaaa acttgtgcag cattgatacc tgtatagata actaggtagc
    56641 taaacatccc gtttttcaag atgttcatca catcgatata ttgttgccat gttgctgcat
    56701 caagtgttcc ggctgtgact aagtttgcta aaactgcggc aatccctgcc acgatcccag
    56761 taccgacaaa tgcaggaatc attggcacaa agatattaga aatgtctttt aataccgatt
    56821 tgattttaga tggtttttgt ttcgattttt gtgccgcttt catttcttgt gcccgttcgt
    56881 ttacacggtc ttttccagat gctgatgaat ttgctgtagc tgtacttaca gaagaaagtt
    56941 tttctcctaa tttcacgcct gccaaatcaa ccatttgctg tgctactttg ttcactttcc
    57001 caggtccgat gatgacttga agctgttcat cttctactac accaagcact cctggaatcg
    57061 cttttaattc agagacattt acaagatcat cattgatgat cttcatacgc acacgagtca
    57121 tgcagtggac aatgctttct acattgccca tgccgcctgc ccctttataa atttgttttg
    57181 ccagttcttc caaagtcagt tcgttttttg ccatggtctt ttccccctca taaggtccct
    57241 tttacaaatc cgtttgcttc agctaatttt gcttgagctt cctctttatc actatttgtc
    57301 aaaatcatga cgatagccag cttaacattt tgatctgctt cttcaaagta cttttcagct
    57361 gtttcgtaat cagcttctgt cgcttgcatg atgattcgtt ttgagcgttc gattagtttt
    57421 tcatttgttg gtttgacatc gaccatcaag ttattgaata ctttacctat accaatcata
    57481 ctgatagtag aaatcatatt caagataagt ttttgtgctg ttcctgactt caatcgagta
    57541 gagcctgtca aaaattctgg acctgcatcg acttcgattg ggaaatccgc gtgtttactg
    57601 atttcggctt gtttattgca agaaatcgtt cctgtgacag caccgatcga ttttgcgtaa
    57661 tctaatccac cgatcacata tggtgtacga ccgctagctg cgataccaat aactatatca
    57721 ttttttgtca aattcagctt gattagatct tcttgcccta gctcataaga atcttcggcc
    57781 ccttcgacag ctacagtcat tgcttcttct ccaccagcaa ttagacctat gaccatttcc
    57841 ggttctacac cgaatgtcgg tacgcattca gcagcatcta acacacctag tcttccactt
    57901 gttccggctc ccatataaat cagacgtcca ccttttttaa aggactcaat cgtgttagca
    57961 atcactggtt cgatacttgt cagttctttt tcaaccgcag cggccacttt ctgatcttct
    58021 ttgttcatta gttgaacggc ttgagaaata ctcatctcat ctaatccaaa agtttcttgg
    58081 tttctgcgtt ccgttgttag gttctctaaa ttgattttgc tcatttttat cttccttctt
    58141 ttcttataaa ttgatagttc ataccagctt tgatttggtt gatcaatggt agctcttctt
    58201 tgataacttt agctactaca ttcacttttt catccgctgg caaatcatat ttggttaatt
    58261 ggatctcacc catatagcgc aaatactttt cgttatctaa agtaatagac cctttcatac
    58321 gcgtagctgt atttcttgct gggataggcg gaatctctcg aaaacgtgca tctacgcttc
    58381 gtatgacatc tcttgcatcg tcttgccgat tcgtatgctt ccctaatata tattcgtaaa
    58441 attcttcatc tacaggttcc gtatggagca agactgtctg ttctttttgg aaagaagcaa
    58501 attgctcctg aacgttttct gacagacctg catctccgat gtaaacaata tccgtgttac
    58561 ttgctaatag atctagagcg cctgcaagag gatggatccc tcgatgttct tccaaagttg
    58621 gcaatccttg atatagtggg cctctcaact ctgtatctcc tggtacaaaa ccttggacaa
    58681 ggagaccttg aattttgagc cattgatttt ttttctgata ccattctttg tccagccctg
    58741 tttcgggacg tggataataa ttatgccaag cttcaatctg tgagaaatca gcttctgctt
    58801 ctttcaattc atcgatatct ttaggcgtga tcgtgctagc attcaaactg attttcaatt
    58861 gatgtgacca gtcggcaatc tgctgattgg aaatatgata atccattctt aaacctgtta
    58921 caccaattgc tttcaaaggc gttagatctt ctaatgaaaa acccgctcgt tccaatgcct
    58981 ctcctgaaat atcgaccatc aattctagtt tattcttttt cgcttcgctt cctagttcga
    59041 tcaatcgctt ttgatatgcc gaaacatcat cttctggtat atgcatggaa gtgaaaatac
    59101 cgacaaagcc attggatgcc atttggcgga tatactgttt cttctcttct gacaaagaat
    59161 cgttcataaa tattgaaaag ccaaacatat tatccctctt tttctgtatc cgtcttcatt
    59221 tctatgacta gagtatatat ctaaagaaac aaaatttcaa tacttttatt aaaataatta
    59281 aatttcattt ctaaaggttg agtttatatt atcaaaagaa ttgtcataac ctaaaaaagg
    59341 cactgctaag caaaagcagt gccttgaaat attttattta aataacacaa aaacataatt
    59401 actcataaga aaccaattct gtattatcta ccatgaatgt aaagaacccc tcattaggca
    59461 tcggatgaaa ataagcattg atcactctta tcaaggcatt atggcaaact aacagataga
    59521 cattttcttc gtcttcgatg cattctttca ataaaggaac gatccgtgca tacacatcta
    59581 agactgactc cccatttggg aatcgtacag cgaacgctaa acgtgctttt tgaaagttct
    59641 catctttgct tggcagtcca tcataatccc caaaatccat ttctaccaat cgttcatcaa
    59701 cggtcagcgg caagctgaga cgatcagcaa ctgcttgtgc tgtatctctt gctcgttgaa
    59761 gaggggaatg gatgattttc gtgattggaa caggcaaatc tactaccttt tctgctagtt
    59821 tctgtgcctg catctgtcct ttttcagtca gcggcacatc tgcccgtccg caaactaatc
    59881 cttgtgcgtt ccaagttgtt tctccgtgtc tcgttacata aagcatgtga ttctctcctt
    59941 cgttggcaaa gttcccctta accatacctt gttgttcttg agattacaag ggttagattc
    60001 tctcaagaga aataatctca gtagatactt tatccaggaa ggtttgatca tgttccacta
    60061 gtaacatggc aggtttcacg ttcaagatca gttgttctaa ttgttcttga ttgaagacat
    60121 ccaaataatt caatggttca tcccatgtat atagttcagc tggctgtgat aaagatttag
    60181 ccaattccac ttttttccgt tggcccatac tcatctgctc gatcttgtta tgaaaaacat
    60241 ctctttccat cccaagcttt cggaggttgt tcaaaaatgc ttggtagtct acttggtttt
    60301 tctctgcaaa ttccgccaac gttcctcgat tgtcttcata attttggctt gcataactaa
    60361 tgctcagatg ttttggctgg tatttttctc ctataacctt gccgttgaat gcccccagaa
    60421 gataatggat aatggatgac tttcctgcac cgttaggacc tgaaatcgcc acccgctgat
    60481 gaggctcgat tgtaaaatga attggctcga ataacagatt ttcataccct aattgaagat
    60541 cttctacgct taaaagtcgc ttatggtgag acgcttggct attcatcgtc aaagaatcga
    60601 tatattcgat atcttttaat agtttttctt tctcgctgat ctgggtctcc atccgattca
    60661 cgattgcttt ggatcgtttc atcgtccgtg cagcatcagc acccactgct cctttattca
    60721 ctcgtctaga ttcagtatcg atgaatccga cttgtttctt tgttttatct ccttctcggg
    60781 aacgagacca ttcggctttt tcagctgctg ttttctttag cctactgact tcttttttca
    60841 atttttcatt ttgagccatt tcaaattcat cacgaagttt tttctgttct tcatagatag
    60901 agaaattccc ttgataaagt tccagttgac ttttttcgat tgctaaaaca tggtccacta
    60961 cttcatcgat aaatccccgg tcatggctga ccacgatgaa gccttgtttt ttctttttca
    61021 aataagccgc tacttgtttt ctaccagaga tatccaaatg attcgttggt tcatcgatta
    61081 acgggaaatg agtgtcatcc acaaataaaa gtgccagtag gacttttgtc ttctctcccc
    61141 ccgatagtgt gctgaattct ctccataaga tttcaggatc tgtttgcatc aattggagct
    61201 ctctttcgat ttcccatatc tcaaaatccg taatatcatt taacacgtaa taggttaaac
    61261 gttctttatc ttttgtctgt tgcgggaaat aggcaaattc ttgctgatgg attacttgcc
    61321 cttgataagg tagtttgttt tgtagaatat tcagtaaagt tgtctttcct cgaccgtttc
    61381 gtccgataag tcctagtttc cattgtgtgt caaaatttag atttgcttgt tcaaataata
    61441 atgtgccttg gctgtcgtag ccgaatgtca gattttttat ttcgatttta gacattttcc
    61501 atcacctcgt aaaaaaagac cagtcctatt ttcagaactg gctaaagagg atgcaagggt
    61561 tggatacaca caaaaagacc catacatcga aaaaaccaag ccaatcccga aaatctgcac
    61621 actgcttcct tgtctccaca aggtacagtc tgaatgcagc tttcatcaat cgacttaatt
    61681 tttcaatgca cggatccctc actttgtcct atatttgaaa ttacgatagc ataaagaaaa
    61741 tgattttgtc aactacttcg ggaggatggt gaaaaatctg ctaagtgtct gtcctaagat
    61801 ttttgttttt tctaatgttt gcctgtgttc cattgcttct tctaaaccta ttggacccaa
    61861 atgaatactt aagacaattg ggagaaaatc agaaagtcct tctagctctt ggtctctact
    61921 tccgcaaata gcgattattg gttttcgata tttttttgca agcactgcta caccgtatgg
    61981 aacttttccg tggatcgttt gctgatcgat ccgcccttct cctgtaatga tgacatctgc
    62041 ttgttcgatc tttttttcca atccagtgat ttggctgact aaatcgaaac cagaaaccat
    62101 cttcgctccc aacaaaaaaa gggctccacc aataccgcct gctgctccac ttcctggaat
    62161 atcatctaaa tccacctccc agaaatcttt tatttgctga gcaatctttc ctgcttgttt
    62221 atctaagaaa gctagcgtcg tatctattcc tcctttttgt cttccaaatt gccaagcagc
    62281 tccttgttga cctgtatatg gattggtaac atctgcagcg ataatcaatt ttactttaga
    62341 aacaagaacg tttcttcgat caaaatgaag ttttttagta gataataaag gatttccttc
    62401 tgtgtaccct tctaaagaag cacccaagga ttggagtaat cctagaccac catcgctaca
    62461 cccgcttcct cctaaagtga caataatttg ttctacttct tgaagcagtg catctttaat
    62521 aagttctcct aaggcataac tggaagcaag tcggatagtt tgatccgttg gtttatcaag
    62581 tagatctaac cccaatgctt gtgcagattc gatgactgcg gtgttttttc cttgccaagt
    62641 tgtcaataaa tagctgattt ttcgctgacg gaataagaga tccatcccat caatggtacg
    62701 ccatgttccc ctgagcgcgt aatagattgc ttctgcagta ttttctccgc catctgcaat
    62761 cggcacattg atttttcttc ctttacgatc ttcccagcca tttagaactg cctgatttag
    62821 ttcaaatgaa gaagcacttc ctttaaatga atcaattgcc gccaaaatat ccatctgtat
    62881 ccctcacttt cttcttaagt aagacacttt ttttcatttt tttcaaacaa aacaatgcta
    62941 ttttcttcca tttttctata tactaaaagg gaactcattg aataaaggag agaaaaaaca
    63001 tgaaaatcgc aatagctggg gccggagcaa tgggcagccg aatcggattg atgctacatc
    63061 aaagcggaaa tgaggtcctc ttgatcgatc gttggcctgc tcacattgaa gccattcgta
    63121 caaatgggtt gattgctgac tttaacggta aagaagtggt cgcaaaactg ccaatctatt
    63181 caccagaaga aatcatcgaa agcaacgaac acgtggactt gatcgtagca ttaacaaaag
    63241 ccaatcaatt agatgatatg ttttgttcga tccaatccat tattactgac aatacttatg
    63301 ttttgtgttt actaaatgga ttaggtcatg aagatgtact ggaaaaatat gtgccaaaga
    63361 aaaatatctt atttgggatc acgatgtgga cagctggtct agctggtccc ggaaaagtca
    63421 cattgttagg tgatggagaa atcgaactag agaacttgga accagaaggc gaagcattta
    63481 caaaaaaagt tgtagaagtc tttcaagaag caaatttaaa tccgatctat agccataacg
    63541 ttcgttattc catttggcga aaagcttgtg taaatggaac attgaatggt ttatgcacga
    63601 ttttggattg taatattgct gaactaggcg cgcaaaaagc ggcagagagc atggttcgaa
    63661 caatcgtatc tgaatttgct tctatcgcag caaaagaagg aatcatacta gatcaagaag
    63721 aagtgtacca acatattgct tctacttatg atcctgacaa catcgggttg cattacccat
    63781 ctatgtacca agacctgatc aaaaaccatc gtttgactga aatcgactac atcaatggtg
    63841 ccatttggcg aaaaggacaa aaatatgata ttgctacacc atattgtgcc tttttgaccc
    63901 aattagtcca tgcaaaagaa ggaatccttg gcgcagaata aaaggctctc tgatgagaat
    63961 cagctgaatc agcagctggt tctctttttt taagcccaat aaaagatcaa aaagaaaaca
    64021 caactctcat gatgccataa gaattgtgct tgtttgtttc agtacataat ctcttcaaaa
    64081 tgtaggtttt ttatttgttt tcaacagagg agaggtcata ttcgtattgc tcataaatag
    64141 tggaatcgtt agtgataaat cgttttgccc aattttctgc atcataaaat tccaatagct
    64201 ctgataggat tggcttaaat ggtgtatgca gaaattccgg taattcatct aaatcacgtt
    64261 ctcgaagcaa aaaaatattt tcaggacgat aaaaatgata atgagcaatc gcttgattat
    64321 ccgtcactag tttcttttga aaatacatgg attcaaatgt ccgcaaagtc actccttgct
    64381 gaccctcccg caacagttcc agaatcccgc gcgattcccc tgtttttttc aggtactctt
    64441 cataagtaag atatccaggt tgttcattcc ctcgatgtgg aagaatgaaa tagttggtcg
    64501 taacatctct ttttataaat tcctgcttat agctttctgc tcgttctttt ctcccattat
    64561 tcgttgcacc aaaaaataga tccgtctttg gttcgctaga agaaaaattc atatgtttcg
    64621 aataaaatga actattatgt ttcagcccaa gttcttttgc ttccaaaaaa tcaaaatgat
    64681 aaatctcatc gattgccggt tcatcttgtg cctgcttcag catcgcctcg tgttctgctt
    64741 tgaagtgatt ccaaaaaaat aacacaattt ttgcattggt aaatgggcgc acgcgtcgag
    64801 ccatctccat atcaaatcca taatctaaaa aaacgatcag ctgataattt gccaactgtt
    64861 gtctagctga tttaatgaat tccgactgta gtaaatcttt tccggaccaa acatctaaag
    64921 agcggatgga aggcaaaaaa taaagtgatt tattttttgc aactagcagt acgtcatttt
    64981 tgttcatctt ttccgcctca ctttctctgt cactttttcc tatgatagcc tgtttaaata
    65041 gtaaaaagcc agtaaaacgt ttcctatatt tgtatgaaaa tttaacattt gtatgaaaat
    65101 atgatgaaat aaatcattct tctattaaaa ttcgcctaaa agttttctga atagttgtaa
    65161 ttgtctgaaa atttgttatc attagtcatt gttaaatatt gctatttatt cttaatataa
    65221 attttgattg tgaatttaaa agaaagaggt catttatgga agataaaaaa ttgaaaaaac
    65281 aacttagctc cagacatatc accatgttag ctttaggtgg agcaatcggt gcaggtctat
    65341 ttaaaggaag tggcgaagcg attgggatcg ccggcccttc tgtattgatt gcttttttga
    65401 ttggtgggct gattttatat atcgtgatga aaggtctggg aaaaatcgtt ttaagcggtg
    65461 gcgacacgca tcacggatta tctggtttga tacgccctta tctaggtgct cattctgctg
    65521 attttactga ttgggtctac tggtctatgt ggattatcaa tatcatcgct gaagctgttg
    65581 cagctgcttc ctttttgcag ttgtggttcc cgcacattcc agcctgggta tttgttttta
    65641 tgttggctgt tttaactacg atcatcaatc tttattcggt acggttattc gcagaaacag
    65701 aatattggct ggcttttgct aaaatcagtg tcattatctt actgatcatt tttgctactt
    65761 atcttgtcgg tcagcaaatg ttgggcacag gcgttttccc tacccttcag caattgactg
    65821 accatggtgg gtttactcct catggtatga agggaatcat cagttctttg cttgtagtta
    65881 tctattctta cggcggttct gaactgattg ctatcacggt aagcgaagca gatgatccta
    65941 aacgtgcgat tcctaaagca atcaaaggtg tcatgggaag aatcatttcc ttttacatca
    66001 ttcctttgtt tttgcttttg attctttttc cttggaatac tttagcaggc acgaatgtca
    66061 gtccttttgt gatggtattt gaaaaaatga atatcccatt tgcagcggat atcgtcaatt
    66121 ttgtgattgt ccttgctttg ttctcatcta tcaattcggg tgtgtatgca tcttcaagaa
    66181 ttttgttctt ccgtttgaag gatcgaaaag gttcctctag aaaactagct gttttaaaca
    66241 agcatcaagt accgcaacgt gctgttttat tttgtaccag tgttctttat cttggtgtag
    66301 ctctttctta ttttgtcggt gacaaattat ttggctatct ggcaggttcc ctttcgtata
    66361 cagtattatt gatctggatc attatcagtg cggcatcctt tgtactggca ctaagaaaag
    66421 gaacattatg ggataaagga atcagctttt ttgcattagc tgtcttagga ttgattttcc
    66481 ttggtatcct gttcacgaac tccattgggg taactgtatt gactggcctg ctttacctgt
    66541 tcatttattt cagttatcaa aaaaagaatg atgcgttcgt attgacgaat gaatgaaatc
    66601 gatagaaaat tttattttat ttatgtggaa tagatggagc tattgaagaa aggagttgtg
    66661 acaaaagtct tgttgcaact cctttttccg aataaacagt ctcatgacct cttggtaaac
    66721 ggtgttcaaa aaccctctgt gcaaaataat tgattgttct ccatgctcat gacatgatag
    66781 aagaaaggaa tgaaaaaaag gagtttgttt taaatgaaaa agtattggaa gtttttgttg
    66841 atgatcggtg tttcaacggt agttatgttt ggtatgatgt acttgaatgt ctatgcgctc
    66901 gatcatatct tcttcagtcg tacacgagta ttcatggcgt tgatgatggg tgcagtcatg
    66961 gcagtcatca tgctgttgtt catgtggaaa atgtatgaaa acaaaaagat aaatgttatg
    67021 atcttagccg ctagtcttct tgtttttgcc ggttccttgt ttatggtacg aagccaaact
    67081 actgtcaacg acacagcttg gatgaaggcc atgattcctc atcattctat cgctatcctg
    67141 gcaagtaaac gagctgattt aaaagatcct gaagtaaaaa aattagcgga agaaatcatt
    67201 caggcacaag aagaagagat cgacaaaatg aaaaaaatga tcaaagaaat ggaatgacca
    67261 ttatccgtcc aaataaaaaa agaggatgtt ccagaagtta tcagcttcaa gaaataagaa
    67321 gaagctactt ctggaacgcc gtgaataagg ggttgtgaaa aagctgccct gcatcaagta
    67381 ataagaacag ccaaacaaaa atagcttctc ctatttttcg tttggttagg cttattaccg
    67441 cagatgcaag cttttgaaca ccgtttatta agaggttgta aaatcagcgt tctgacctga
    67501 gtattagaga gacaaatgga aaaatagttc ctcatatttt gccatttttt gagctaatac
    67561 cgagggtcag ctgattgaac accgtttatc gagaggttgt gaaaaagtcg cttagtttcg
    67621 cgtattaaga aaaattttgt gaaatggctt tccacatttt tgtataaatt tggcttaata
    67681 ccgagaaact ggcttttgaa taccgtttat tcgtaaaagg gattgtgaca aaagtcttgt
    67741 cacaatccct ttttatgttt
//
LOCUS       DAFEIE010000006        65561 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFEIE010000006
VERSION     DAFEIE010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65561
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.006"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(23..391)
                     /locus_tag="LP345_000478"
     CDS             complement(23..391)
                     /locus_tag="LP345_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBL1759287.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(1002..2393)
                     /locus_tag="LP345_000479"
     CDS             complement(1002..2393)
                     /locus_tag="LP345_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBL1759288.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2606..2992)
                     /locus_tag="LP345_000480"
     CDS             complement(2606..2992)
                     /locus_tag="LP345_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBL1759289.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(3048..3671)
                     /locus_tag="LP345_000481"
     CDS             complement(3048..3671)
                     /locus_tag="LP345_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBL1759290.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3735..4403)
                     /locus_tag="LP345_000482"
     CDS             complement(3735..4403)
                     /locus_tag="LP345_000482"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL1759291.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4415..4855)
                     /locus_tag="LP345_000483"
     CDS             complement(4415..4855)
                     /locus_tag="LP345_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759292.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4914..5585)
                     /locus_tag="LP345_000484"
                     /pseudo
     CDS             complement(4914..5585)
                     /locus_tag="LP345_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5770..6168)
                     /locus_tag="LP345_000485"
     CDS             complement(5770..6168)
                     /locus_tag="LP345_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBL1759293.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(6165..6938)
                     /locus_tag="LP345_000486"
     CDS             complement(6165..6938)
                     /locus_tag="LP345_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL1759294.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6935..7618)
                     /locus_tag="LP345_000487"
     CDS             complement(6935..7618)
                     /locus_tag="LP345_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL1759295.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7785..8672)
                     /locus_tag="LP345_000488"
     CDS             complement(7785..8672)
                     /locus_tag="LP345_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1759296.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8669..9538)
                     /locus_tag="LP345_000489"
     CDS             complement(8669..9538)
                     /locus_tag="LP345_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1759297.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9675..10961)
                     /locus_tag="LP345_000490"
     CDS             complement(9675..10961)
                     /locus_tag="LP345_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1759298.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            11234..11812
                     /locus_tag="LP345_000491"
     CDS             11234..11812
                     /locus_tag="LP345_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL1759299.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11812..12741
                     /locus_tag="LP345_000492"
     CDS             11812..12741
                     /locus_tag="LP345_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1759300.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12738..14474
                     /locus_tag="LP345_000493"
     CDS             12738..14474
                     /locus_tag="LP345_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL1759301.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="LP345_000494"
     CDS             complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="LP345_000494"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBL1759302.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(15370..15879)
                     /locus_tag="LP345_000495"
     CDS             complement(15370..15879)
                     /locus_tag="LP345_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBL1759303.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="LP345_000496"
     CDS             complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="LP345_000496"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBL1759304.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRCIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(17180..18271)
                     /locus_tag="LP345_000497"
     CDS             complement(17180..18271)
                     /locus_tag="LP345_000497"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBL1759305.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="LP345_000498"
     CDS             complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="LP345_000498"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBL1759306.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="LP345_000499"
     CDS             complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="LP345_000499"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBL1759307.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="LP345_000500"
     CDS             complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="LP345_000500"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBL1759308.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(22234..23208)
                     /locus_tag="LP345_000501"
     CDS             complement(22234..23208)
                     /locus_tag="LP345_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBL1759309.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(23189..25072)
                     /locus_tag="LP345_000502"
     CDS             complement(23189..25072)
                     /locus_tag="LP345_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBL1759310.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(25090..27315)
                     /locus_tag="LP345_000503"
     CDS             complement(25090..27315)
                     /locus_tag="LP345_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL1759311.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27430..28464
                     /locus_tag="LP345_000504"
     CDS             27430..28464
                     /locus_tag="LP345_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1759312.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28531..29543)
                     /locus_tag="LP345_000505"
                     /pseudo
     CDS             complement(28531..29543)
                     /locus_tag="LP345_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(29621..29809)
                     /locus_tag="LP345_000506"
     CDS             complement(29621..29809)
                     /locus_tag="LP345_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBL1759313.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(30249..30377)
                     /locus_tag="LP345_000507"
     CDS             complement(30249..30377)
                     /locus_tag="LP345_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL1759314.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(30380..31753)
                     /gene="rlmD"
                     /locus_tag="LP345_000508"
     CDS             complement(30380..31753)
                     /gene="rlmD"
                     /locus_tag="LP345_000508"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL1759315.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31864..32919)
                     /locus_tag="LP345_000509"
     CDS             complement(31864..32919)
                     /locus_tag="LP345_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL1759316.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32929..34359)
                     /gene="gatB"
                     /locus_tag="LP345_000510"
     CDS             complement(32929..34359)
                     /gene="gatB"
                     /locus_tag="LP345_000510"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBL1759317.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(34356..35828)
                     /gene="gatA"
                     /locus_tag="LP345_000511"
     CDS             complement(34356..35828)
                     /gene="gatA"
                     /locus_tag="LP345_000511"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBL1759318.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPAKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLAHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35828..36133)
                     /gene="gatC"
                     /locus_tag="LP345_000512"
     CDS             complement(35828..36133)
                     /gene="gatC"
                     /locus_tag="LP345_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBL1759319.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(36239..38275)
                     /gene="ligA"
                     /locus_tag="LP345_000513"
     CDS             complement(36239..38275)
                     /gene="ligA"
                     /locus_tag="LP345_000513"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBL1759320.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(38292..40526)
                     /gene="pcrA"
                     /locus_tag="LP345_000514"
     CDS             complement(38292..40526)
                     /gene="pcrA"
                     /locus_tag="LP345_000514"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBL1759321.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMGFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40681..42240
                     /locus_tag="LP345_000515"
     CDS             40681..42240
                     /locus_tag="LP345_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBL1759322.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(42351..44282)
                     /locus_tag="LP345_000516"
     CDS             complement(42351..44282)
                     /locus_tag="LP345_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1759323.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(44300..45214)
                     /gene="pfkB"
                     /locus_tag="LP345_000517"
     CDS             complement(44300..45214)
                     /gene="pfkB"
                     /locus_tag="LP345_000517"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBL1759324.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(45211..45963)
                     /locus_tag="LP345_000518"
     CDS             complement(45211..45963)
                     /locus_tag="LP345_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1759325.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(46122..46331)
                     /locus_tag="LP345_000519"
     CDS             complement(46122..46331)
                     /locus_tag="LP345_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759326.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(46342..47670)
                     /locus_tag="LP345_000520"
     CDS             complement(46342..47670)
                     /locus_tag="LP345_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759327.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47806..47961
                     /locus_tag="LP345_000521"
     CDS             47806..47961
                     /locus_tag="LP345_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759328.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(48035..48622)
                     /locus_tag="LP345_000522"
     CDS             complement(48035..48622)
                     /locus_tag="LP345_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBL1759329.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48705..49955)
                     /gene="clpX"
                     /locus_tag="LP345_000523"
     CDS             complement(48705..49955)
                     /gene="clpX"
                     /locus_tag="LP345_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBL1759330.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(50202..51491)
                     /locus_tag="LP345_000524"
     CDS             complement(50202..51491)
                     /locus_tag="LP345_000524"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBL1759331.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51645..52577)
                     /locus_tag="LP345_000525"
     CDS             complement(51645..52577)
                     /locus_tag="LP345_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759332.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52734..53393)
                     /locus_tag="LP345_000526"
     CDS             complement(52734..53393)
                     /locus_tag="LP345_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL1759333.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(53396..54421)
                     /gene="sppA"
                     /locus_tag="LP345_000527"
     CDS             complement(53396..54421)
                     /gene="sppA"
                     /locus_tag="LP345_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBL1759334.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54434..54724)
                     /locus_tag="LP345_000528"
     CDS             complement(54434..54724)
                     /locus_tag="LP345_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759335.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            55133..56938
                     /gene="glmS"
                     /locus_tag="LP345_000529"
     CDS             55133..56938
                     /gene="glmS"
                     /locus_tag="LP345_000529"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBL1759336.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(57010..58365)
                     /locus_tag="LP345_000530"
     CDS             complement(57010..58365)
                     /locus_tag="LP345_000530"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBL1759337.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(58389..59558)
                     /locus_tag="LP345_000531"
     CDS             complement(58389..59558)
                     /locus_tag="LP345_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759338.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59555..60442)
                     /locus_tag="LP345_000532"
     CDS             complement(59555..60442)
                     /locus_tag="LP345_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBL1759339.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60631..64323)
                     /gene="nifJ"
                     /locus_tag="LP345_000533"
     CDS             complement(60631..64323)
                     /gene="nifJ"
                     /locus_tag="LP345_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBL1759340.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64522..65043
                     /locus_tag="LP345_000534"
     CDS             64522..65043
                     /locus_tag="LP345_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL1759341.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT        18251 a        14204 c        11673 g        21433 t
ORIGIN      
        1 aaaaacaaag tctttatttc tattatttac ctgtaaccgc aaagtagttg ccatcgggat
       61 cagcaaagtt aaagacatat tcttctccaa gctgtaccat atcacctaat gtgactgatt
      121 gcgtctgcat ttttttatat agtccaaaga tatctttact gtaaaacatc aaagatgggg
      181 cactagtagc tgtgccaggt gaatgggact caacaaatgc tcgatcatat aacagaaatg
      241 aggtttgact gtcctcaact cctacttcaa ttataagcgt cccatccatt tcttgacgat
      301 ctttttccgc aaagccaact gctctccaaa acgttgcatt tttttctaca tcgtccacat
      361 aaagcatgat ttttatttca ttcgtaaaca tctgtttcct cctaaacgat ctgttctaac
      421 attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag ctctcaacag
      481 aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt ttttgttatt
      541 tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata aaaaaagagg
      601 tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca actcctcggt
      661 cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct ctttgtgact
      721 cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
      781 cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg ctgttcttat
      841 tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag aagtagcttc
      901 tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa acttcttctt
      961 atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt cacatcgatc
     1021 actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc acttgtcacg
     1081 ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc gattaatggt
     1141 tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc taaaacgatc
     1201 agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact gattgttaca
     1261 attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc tgctggtgcg
     1321 acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc aatagacaaa
     1381 ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt tgtctgagtc
     1441 tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa gctcaatacc
     1501 ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa aatcagtgag
     1561 tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt acctaaattg
     1621 acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa tactccataa
     1681 ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag actgtcgact
     1741 aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag ataagcgatt
     1801 ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact acctgctaaa
     1861 tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga taagttttca
     1921 actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc tccttgtgtg
     1981 aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa tgctgcaata
     2041 gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag cttttcagaa
     2101 actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat aactagcatt
     2161 tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga ttgagtaacg
     2221 actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat accaactcct
     2281 aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg atagaacaca
     2341 tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt catttttctc
     2401 ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga gaatgattct
     2461 tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac gatttttatc
     2521 gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg atagctttaa
     2581 tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa ttcaatttta
     2641 ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt acgatatcga
     2701 ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga ccttcaattt
     2761 tccgattgag gatatgattg atctgactca cacttccaga taaaacatat gtatcaaaca
     2821 ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag ttttcgatcg
     2881 tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg ttcggcaatc
     2941 tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc atataatttt
     3001 atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta ctttttaatg
     3061 atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc cgggatctca
     3121 cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt ccctgcttcg
     3181 atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg aaaagtatcg
     3241 atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc gatccctact
     3301 acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt tgattctgtc
     3361 aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc cagtacttgt
     3421 ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg gtgaaataat
     3481 tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt agaatacttt
     3541 ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt tagtgcttgc
     3601 catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa gtcccatata
     3661 taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct ctcactttta
     3721 gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc tgctaatgta
     3781 tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc aggaacatct
     3841 tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag taaatcttgc
     3901 cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg attcactgtc
     3961 atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata tctgcggtca
     4021 aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca tgtttttact
     4081 tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag atccccataa
     4141 tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc catttcttct
     4201 agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac ggcatcgaat
     4261 tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt tcctttttct
     4321 gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc gctttcgcca
     4381 tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg aattttatac
     4441 cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc tgcttttgat
     4501 gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact tgctttttgt
     4561 tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa cgttgattct
     4621 catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat ccgaaaaaga
     4681 cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa ctaaagacaa
     4741 gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt ccctgcataa
     4801 gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc atcatattat
     4861 ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa gccttaattg
     4921 gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc aatcacaatc
     4981 actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg aagaaacagc
     5041 ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat caattgagga
     5101 aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt cgttttgatc
     5161 agattccgtt ttttactgat cactttttaa aagcttttta gaatcttttg ctgacgtcta
     5221 aaaatagaaa aagaattttc gtcatctatt tgataacgca tttgtttttg cagttctgct
     5281 gcagtcagat ggatcttccc atcgtttgta tcgatcatta aaccttctgg aaacagttca
     5341 accactgctc gatcccaaga ttcaagagaa agctcgatat aatcttttac tggtaattcc
     5401 aattctacct taaaaaagtg caaaacagcc gacagccctt ctgcttgata gatttctcct
     5461 aatgttagcc cctctagatg gaactctggt gaaaaatgca gcaatgtttt attttcctgc
     5521 aattgaacat atagaaatgt agatcgctca atcagagtat cttttaaaac aactaaaaaa
     5581 ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa aagaaagtct
     5641 gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac gagaaaaata
     5701 caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat ttcctcttca
     5761 aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa gttcttgcat
     5821 tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt ctacatcaat
     5881 actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa tcgcatccat
     5941 tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt ctggcgaaat
     6001 gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat gtaagatcgt
     6061 tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca ttcctccgtc
     6121 aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt gctttccccc
     6181 aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt ataaatatat
     6241 cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac accaaacccg
     6301 tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat tgataaaata
     6361 aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat tgctaaaaag
     6421 atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat caagaaataa
     6481 taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc gccgatccca
     6541 attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa ttcttcaacc
     6601 tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc cattaaaaag
     6661 ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc taaatgctgt
     6721 cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc aatagtcgtt
     6781 atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa actaatgata
     6841 ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc catggtaacg
     6901 atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc cccaaaatca
     6961 tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg tcattttcat
     7021 ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata aatggaacag
     7081 ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat tcggaactgg
     7141 tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga taataggata
     7201 gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg acgctgacga
     7261 tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact tgttgtccca
     7321 aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat cccaaactga
     7381 ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct ccgacttcca
     7441 tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg attgccgcac
     7501 caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac gttaaaatga
     7561 caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt tttagcatgt
     7621 atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga gcacaaactt
     7681 aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa agtatctttt
     7741 tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt tacagagccg
     7801 atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt tggtaaagta
     7861 gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc acccatagca
     7921 gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa gggccataaa
     7981 taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt atttttagcc
     8041 gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa tcgagcggct
     8101 tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat caaaaaagca
     8161 gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac cgttccgttc
     8221 aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac catcatcgat
     8281 agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc aaatccatat
     8341 cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat catcgctgaa
     8401 ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa attgatgatc
     8461 aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt cgtcattccc
     8521 aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa tgctgtatac
     8581 tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac gttggggcgt
     8641 tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact ttcgtttgga
     8701 ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc gcatatccaa
     8761 aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg gtcgttgcat
     8821 ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat gtcccgatcg
     8881 tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc actttgataa
     8941 actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc gaatcaatat
     9001 tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa gtgatcgaaa
     9061 gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt gtgtcaatca
     9121 taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga cttttcatga
     9181 tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt cgaaacaacc
     9241 ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct agaaacaaca
     9301 tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt ttaaaagttg
     9361 catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg acagggggac
     9421 cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg attgatatca
     9481 aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc tgcttcattc
     9541 ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga caatatctgt
     9601 aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga agaaattcac
     9661 ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt atctgctagt
     9721 accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac gactgcttca
     9781 attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca tgttgaaaaa
     9841 tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc ttcttgttca
     9901 ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc catcagttct
     9961 tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc agctactcct
    10021 ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg cagattttct
    10081 ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc tccttggatc
    10141 gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg tatcgcagtt
    10201 actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag agtggcaaac
    10261 aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc cccatcttca
    10321 gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag gtcagaagga
    10381 ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac ttgaatatac
    10441 tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc catcagatcc
    10501 gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat tttatctcct
    10561 actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat agcagacaaa
    10621 ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc ttcaatcaag
    10681 acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag tttctgaacg
    10741 atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc ataaactttt
    10801 tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac agtgactttt
    10861 tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc tgatgctgcc
    10921 gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg ctccttttcc
    10981 atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa cggtttcttt
    11041 attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa tcaactatga
    11101 caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt ctttaaaata
    11161 aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga ctattcttaa
    11221 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
    11281 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
    11341 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
    11401 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
    11461 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
    11521 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
    11581 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
    11641 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
    11701 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
    11761 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
    11821 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
    11881 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
    11941 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
    12001 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
    12061 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
    12121 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
    12181 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
    12241 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
    12301 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
    12361 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
    12421 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
    12481 caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat ctttactgaa
    12541 aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc
    12601 tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa
    12661 ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt
    12721 aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc
    12781 tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc
    12841 atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa
    12901 agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg
    12961 attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc
    13021 ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga
    13081 tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc
    13141 tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac
    13201 gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag
    13261 cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg
    13321 ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg
    13381 agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa
    13441 atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt
    13501 caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc
    13561 aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata
    13621 atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa
    13681 aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc ttaaaagcta
    13741 ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc aatcaattgc
    13801 taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag aaacgttcgc
    13861 ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat acgctgacta
    13921 gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga atcgacagtt
    13981 tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca gtcaaggaag
    14041 aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc gaaagaatct
    14101 cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat atgatccttc
    14161 aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa ggattcatca
    14221 cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat aacggcgatg
    14281 gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc ggcatcagcc
    14341 atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg atccaatcag
    14401 tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa aatcaatcag
    14461 aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta aataaatcaa
    14521 tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga taacagccca
    14581 atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct actaatgtca
    14641 ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta gttttcaatg
    14701 gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc agcattttat
    14761 gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt actggagctg
    14821 actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg ttcaactcat
    14881 tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt tctaatgaag
    14941 caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca gcagttgttg
    15001 attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt tgtgattgtg
    15061 ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg cctaaaagct
    15121 gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt ttggaaagaa
    15181 gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg acagccagat
    15241 cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac gcagtcaatt
    15301 gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct ggccctagat
    15361 agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct tttctggtgt
    15421 ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa gtcgttgtgc
    15481 caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa tagacgtttc
    15541 atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa gaacaatcgg
    15601 ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac cagtcgcgat
    15661 aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc gaaagctttt
    15721 ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct caatctttgt
    15781 atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga ttgttgtttt
    15841 tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct cctgacacaa
    15901 gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca gctccttcta
    15961 gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg attcgatgat
    16021 cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg atcagaccgt
    16081 ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc gcatcaattc
    16141 tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt ccttctgctt
    16201 gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg atttctccac
    16261 caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat tggttctgtt
    16321 cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct aagataccag
    16381 ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga acaagaagtc
    16441 ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc tgttgaccag
    16501 ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc cttccgccaa
    16561 attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg attacggatg
    16621 tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca ctggctacag
    16681 gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt ggtagatact
    16741 ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc atcactcgcc
    16801 ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa ggctgtccag
    16861 ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca attgattcgg
    16921 ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct tcctcttctt
    16981 cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct tctgcgcgca
    17041 aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg cagcgatggg
    17101 aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt tgttgtaata
    17161 attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta gacataatga
    17221 ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt attcctaaaa
    17281 tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct tttccgatca
    17341 gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat aaatcaaaaa
    17401 aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct tttgcccgat
    17461 tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct atttgtgtca
    17521 tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc aacaaaatat
    17581 ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag cctcctgctg
    17641 ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg actaagccag
    17701 ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt tctcttgctg
    17761 taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt tcaacatctt
    17821 ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt ttagcatctg
    17881 ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca aaccgaagat
    17941 ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc gtaatgatga
    18001 cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt gtacggacgg
    18061 gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca cttgcaacgt
    18121 aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta tcccaaccaa
    18181 ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca ccaatcagtc
    18241 caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta gtaatgtttc
    18301 aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc acttgggaat
    18361 tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac gacgctagct
    18421 gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc ttttgtatcg
    18481 atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac cccgcgaatg
    18541 acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt ggtacgtcgg
    18601 aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc tggtaatgaa
    18661 ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact aaccacagct
    18721 tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa tccagctgga
    18781 acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt ctttgtctga
    18841 tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac ttctgacgct
    18901 tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc ttggattcca
    18961 ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat ttttttggca
    19021 attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc aagcacattc
    19081 cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc tggacgcgga
    19141 cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga catgacagtt
    19201 gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc aattgttttg
    19261 ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat ccttcctcct
    19321 ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc tgacagaggt
    19381 aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga ttctcccgca
    19441 gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg tgggaacagg
    19501 aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc ttcctcttgc
    19561 tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat cgtacgtaat
    19621 cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag ttggagacaa
    19681 gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc cttctccatg
    19741 actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat gaccaaaatt
    19801 taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc gtttgatttc
    19861 caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt ctttcagctc
    19921 gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga tttcagcgat
    19981 tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa tcaatacacc
    20041 agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga ctgctgtctt
    20101 cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa cgaaatggat
    20161 cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc ctccaccaag
    20221 tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt ataactcagc
    20281 tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga ctggttcaaa
    20341 attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa cgtttgtatc
    20401 agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc cagcctgttc
    20461 tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta cagtaagcat
    20521 tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat cttttccatt
    20581 gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc attcaacgat
    20641 tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat catgccatct
    20701 gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat tcctgtacca
    20761 tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg gacagcactt
    20821 aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc gataaaaatg
    20881 acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc attgatcgta
    20941 ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc agatagcagt
    21001 ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc agccaccata
    21061 tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc atcagccgct
    21121 tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg agaagtacgt
    21181 ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat tcgcgcacat
    21241 tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac gaaactgccg
    21301 tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa ttctcgagaa
    21361 gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata gcgtgtaaat
    21421 gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg ttctgttcct
    21481 tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt ttttatttgt
    21541 tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt cttttgttta
    21601 cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt aattcctact
    21661 aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat gacccagata
    21721 atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc ttcaacgagc
    21781 cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc tacgtggctg
    21841 taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt ttgtacccac
    21901 gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca gttttgtaag
    21961 ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc tagtatagac
    22021 ataaaaaaat cgactgtcaa tcatttttat gaaacttttt ttaattttct gatagttaac
    22081 tttgtttttc agaaaaataa caattggttt tattgaagaa aatagtcatg aacaaaagta
    22141 tctgagaact tttttactct cttgttcatg acatatagaa taaagcagct ttgtcttgta
    22201 aactccgttt ttcaaataat aatctaaaga ttgctactga ataataaagc cgatttcatg
    22261 gtcctcttcg ctgctgattc ggtaaggtga ctcaacatcc gctccccagc tattgatacc
    22321 cccgactcct cttacttttg caaaaatcgt aagaaccgtt cgtctttctg gcggtagttc
    22381 ttctatatgt gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg aaaaagcaaa
    22441 tggcgtatcc tgctgttcaa atcgcaacga aaaatcttct tgatctttat ccgtattatc
    22501 caacgtttga tttcttgtta gttctaccca tttcgtttcc atatgcatgc cgcattcttg
    22561 gggaacaagg tatggggaaa cggggagtcc tgccacttta taaatacctt cgacaccacc
    22621 agccatccga tccggatatg tttcccctga taggccttca tactcaaaaa attttgcttt
    22681 cgttggcata atgaacctta aacccaatgc gggtaattcc ggtaatcctt tttgtccata
    22741 ataatgcata ttgacaagca ttttaccctc tccagcgatt tggtaggaaa ttgtcacttg
    22801 ggtttttggt actgtgttga tttccagtgt aaaaatgatt tcaaccgttt cagcgtattc
    22861 attacttgaa tattgattat ttactggagc aatcggcaaa tcgatctttt tattgtccac
    22921 cagtacttct atttctttga cttttggata caatccggct cctaaccaca taccggattt
    22981 aaatccaaat ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa ctggaagtgt
    23041 ttcccggtat agccattctt ttccgttttt attgagcgat tccagtccgc ctcttgtata
    23101 agaaaaaata taatgcgtat tccccgattt gacacctaat gtacagtcgc cgaagacgat
    23161 tgcaactttt tccgtatcca tatgactttt atttactgta tttttcataa taatatctta
    23221 cctcctgcat ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc cctgagaatt
    23281 catagtcact tggtttatcg tcaaagtcac cgccatagcg catcacttct ctgcctgtga
    23341 ttggatcagt cacttggatc gcctgatctt taaaatccca tatatagcct ccttggtaca
    23401 tttcataacg atcaagcaac gtcatgtaag aatccattcc acctaacgaa ttccccatgt
    23461 catgcatata ttcacataag atgaacggtt tttccgcttt attttcaagg tagtcaatga
    23521 tctcttctgg tggcgcatac atgcagcttt ttacatctga aatcgaatct tcgaatgctg
    23581 gatttggaaa attcccttca taatggacaa gtcgatcggg gtctactttt ttgaagtaat
    23641 cgttcatttg tcgaatgttt tcttccgcat aagattcatt tccaagagac caaaaaagaa
    23701 tacttggatg gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga acagccgcct
    23761 gccactgagg tactgcacct ggtacgttgt aagaaggctc aaatgcgccc attttttgcc
    23821 atgagccatg ggattcgagg ttcgtttccg ccatcacatg gattcctgct tggtcgcata
    23881 aataatacca agtgatctgg ttggggtaat gagatgtccg tacgccgttg atctttgcat
    23941 tttttatgat agccaaatct ttttccatat cttctatagt gatggcgcgt ccttttttcg
    24001 gatgccactc atgtcgattt accccgttga taatcatccg ttttccattg aagtagatga
    24061 ttttatcttt gatttcgatt ttacgaaaac cgaaggaata gtcaatatac tccgttactc
    24121 ttttttcttc gtctatcgtc tccaattcaa gcttatataa attgggctga aaatgccccc
    24181 acagtgccac attttcaaat ccatcgatgc gaatcgtcat ttgctctttt aacggatatt
    24241 gctgttgata gatttccttc ccatcaggat ctagtatcgc tacattcagc tgactgtttt
    24301 tggctacttg ctcaaaagac aaatctactt caagtttgcc attttgacat ttgtcatcta
    24361 agcgaggttt gatccaaaga tcttctaaat ggttttgtcc tcgagcaact aagaagacat
    24421 ctctgaagat cccaaaaaat cggaaaaagt cctgatcttc caagaatgca gctgtacttc
    24481 ttttgtaaac ctccacagct agaatatttt cttcttccaa ataaggtgtt aaatcaaatt
    24541 cagacggagt gaacgaatct tcggcatacc cgataaaatg accattcaac caaataaaca
    24601 ttgcttgttc tacaccagca aaatgaatcg agatttgttt tccctttaga ccttcttcta
    24661 atcgaaaagt cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa aagatccctt
    24721 ccgcctcttt ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt ccctcccacg
    24781 gatacatcgt attgatgtaa tggatcttgt cataatttgc taattcaata tgactaggaa
    24841 cagtgatttc atcaaaagaa caggcatcaa aatctttttt ataaaatgtt tttggtcgta
    24901 ccgaaggatt tggcgaataa caaaaacgcc atgatccatt taaagactgt ttaagggagg
    24961 atgtggtttc tacttcttcc cttgttgcat aacaaacatg atcgctatgt gcatttgatt
    25021 ggttcactct aaaaacttgt ggatcatcta accattttat atttgctttc atactttttt
    25081 ccttctctct cataactttt tgaaatgaag cagttctgtt tggaaatcac cttgaaaatc
    25141 ggggaagtaa agtccaactg tcatcaattc ggcccccgaa aatatccgct tcgaggtctg
    25201 ttcctgataa agtgcctcat catctaaccc catcagatat acttcatgga acgctggttg
    25261 agctgaagct agtatcctcc ctaaaaacac aatagcttca tcttgtttag gagacacaaa
    25321 catccatgcg gcaatatttt cttcaaaagg actcgccaaa cgataataat ggccatactg
    25381 gatcaccgga cgaatcgttt gataggatat aatttggtct tttacttgct tttcttcttc
    25441 aggagacagc tttgtcaaat ccagttcata accaaaaaca gcgctcatag ctgtttctcc
    25501 tcttgttttc aacgaagtag atctgtcggt ctgatgattt ggtacagctg atacatgagc
    25561 tgtgatggac gaaatcggat aagcaaggct tgttccatat tggattttca tacgctccac
    25621 tgcatccgtg ttatcacttg tccatgactg cggcatataa taaataaacc cggcatcaaa
    25681 ccgtccacct ccaccagaac agccttccca taagatttcc ggataatcag ttgtcaaatg
    25741 ttcaagtagt tcataaagcc cgagcatata acgatgcgct acttctcctt gtctctgtgg
    25801 gtcaagggta atcgaataga catctgaaag cgaacggttc atatcccatt tgatgtagtc
    25861 aagaggaatc gtatctaaaa tctttctcat ttgtttctca atcgtctgcc gaacatctaa
    25921 ccttgtaaaa tccagtacat gttgtgatct ggaagcagaa ggcattctac ctggctcctg
    25981 cataagaaaa tcaggatgtg ttcgatacag ttcagaatca accgagatca tttcaggttc
    26041 aaaccataaa ccaaatttca atcctttgct atgagcataa tctgctattt cacgtaatcc
    26101 atttgtcaac ttgccttcat actcgaacca gtctcctaat gaagaattgt ccgcatctct
    26161 ttttccaaac cagccatcat ctaatacgaa catttcgatg cctagctcct ttgcttcatc
    26221 aatgatcgcc ttgatttttt cactattgaa gtcaaagtaa gtggcttccc agttattgac
    26281 cagaatcggc cgttcagcaa attgatgacg acctcttgcg attctttcac gtagcaactc
    26341 atggtggatc tgactcattt tgttcaatcc ctgacttgag taagaaagga tcatttcagg
    26401 tgtttgaaaa gactggcctg cattcaattc ccacgaaaaa cgatggctgt tgatcccacc
    26461 gacgactctc aattgattga tctgatcttt ttcaagttcg aaagaatggt tgccggaata
    26521 aacaaattga agtccgatcg cttctccagt attttctgtc gtatgatgat gaactaaagc
    26581 aataaagtta ttcatatggt gactgctcgt tcctcgacgg ctttcaaata cttttgttcc
    26641 agataaaaca gattgccgtg aaatctgtct ttcattgaca tgtgctcctg gcaaagcaat
    26701 gacttcatca aatcgcctag tatgggcaaa gtctagctgg aaactagccg ctttttctag
    26761 tttgattgtt tctccggttt catttcttat ctttacagat cgtgtgatca ctgctctatc
    26821 agtaaatatg gtatagaaca aatcgaaata aatcgctgtt tctctatcct taagtgaaat
    26881 caccaacgtt tgtgcctctg acttgtccat cacataagtt tgaggcaagc cttcgatctc
    26941 tggcttccca tctgtaatat aatggctgtc atatctcaga tccagtaagt ctgatccatt
    27001 cttgcgctga atgatcgatg cgggcgttcg aaagtccatg ctgccatgag aagagtattc
    27061 ttgcggtagt gtatctttcg acagagaccg gtcaggattt aagggaacat ttcctgaaaa
    27121 tccacgatct cttcggggat aatttttatt gtctttgtac tgcttgactg gtttgccaaa
    27181 ataaatatgc gccaatacat tgctttcttc tatctttatc agataagaaa gaaatgtatt
    27241 tcgtaaatgg aagactcggc tcttttcatc aaataagatg aaatttttat ctgtttttct
    27301 atgcgtaata tccatcattt cactcccaac aaaacggaaa ccgtttactt ttttttataa
    27361 ttcctgtata ctgtttacta aacaattttg tcaataaaaa ttttttattt ttttgaggag
    27421 tgtgtaaaaa tggttggaat tagagatgtc gcacgaaagg caaatgtctc tcctgctaca
    27481 gtttcccgtg tgttgaataa cgatcagacg atccatgtgg ctcagactac tcggcaacgg
    27541 atagtagagg cagctgctgc gttggattat gacatcagta ctcgtaaata tatcaaaaag
    27601 agaatgcctt cgattggtgt gatctctacg atcggcaaag cgagcgaaga acaggatatc
    27661 tattacaaac atttgcgagt agggatggaa gaagaagctc gacgtctgca tttagggatg
    27721 aatcgaatct ataatctatc tgataatcct aaacaatggg aagatctaga tcagttaggt
    27781 gcggtgatcg ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt aaaacaaaac
    27841 atgcaaatag tcgtcgtgga taaccctgac atccagcaag aggtcgatat ggtgtatgca
    27901 gatcttgaac ggatgactaa aaccgtactg gaattgttct tagaaaatgg tcataaaaga
    27961 atagcctata tcgggggata taaagtcgat atggatgaat tcggtgggaa gcagatttct
    28021 ataaatgaaa agaggatgcg tgcctatcag cattttatga tcgatcatca cttagaaaaa
    28081 tatatgtctt atcatctagg tggctggaca gaaaaacaag gtgaggtact tgcgactaat
    28141 ctattagaaa atgaatcccc tcttcctact gccattcttg tcgggagcga tccaatggca
    28201 attggtgtct atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga gattgttgta
    28261 gcaagctttg ataatatcga gacaatcgca aacctctccc ctggcttgac cagtgttcaa
    28321 atcaatgcga aatcaattgg gcaagcagct gttcgaatgg cattggagcg aattgacggt
    28381 atacgggacg aaccaatcat tttgacttat cctgcacgat tgattgttag ggaaagtttt
    28441 atcccaagaa caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg tttcttcata
    28501 ctcaaaacga aacggctttt tcacaacctc ttacttatac ttattcacaa aatccaatgt
    28561 ctgctggtaa caattttgcg attcttttag cgtgtaatca aattggtatt catgggtaat
    28621 ctcttttttt gtatctgtat aaaacaagga ttgcacgggt acctttaatt ctgtcaaccg
    28681 attttctaat gcttgacctt gctcctggaa tgagtatgca tttccgtcag ttatatacgt
    28741 tggcggaaat tccttagaaa catggtcagc cacactagct tctttcaatt gctcactcgt
    28801 tttccaatct tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa acttcataaa
    28861 tcgatcatcc gaatgctgct gtgctgttag cttcaaatca acaggtccgc aataagaaat
    28921 ggttcctttc agactatctt ttggaagtag atgtttgatt ttcatttgtt tagcatacgc
    28981 atcattcgtt tgtatagctg catattgcaa tgcgatttgt gaacctgcac tatctccacc
    29041 aaaaaataat tgttccatgt ctagcaattt gtcgtctttt tcttcagcta ataaatcttt
    29101 gatcagttca ttcacttgaa gaacttgatt agggtattct gaatcaggcg ctaattcata
    29161 attcatcgca accactgcga tgttggcgtc tgaaactaat tttgtcgcaa attctttgac
    29221 acccgattta tctccgccga cgaatcctcc accatgtacc caaaatagaa caggaacagg
    29281 ccccttgctg tttttggata gtagatgtca taagtattct ctttatactt ggactcatac
    29341 gtcaaatctg tttttttcgc cacgtttttt tctgcttgat cgaacgtttt tttatcagtg
    29401 atttgaacag tatttgaaaa catatggttg atcaagaatg ctccaggtct gggggaaagc
    29461 tggaaggcaa gaaagattgc aaacgcgatc ccaagaatga ttccgaagaa ccatccgata
    29521 aatttaagaa ttttcttttt cataaggctc cctcagtagt tagtattaag cattctgatt
    29581 ataccatagt gttatttcct atcaagctct cctagatgat ttaatgattt tccccaaact
    29641 tcttctgcaa tgcttttgac aaaagaaatt ttttccattg ttcttcaaac aaaacatttt
    29701 cttcttctgt tgaagcaaat ccacattgag gacttaagca caaacgatcc aaaggcagat
    29761 atcgtgtcgc ttcgtagatc cggtcaatca cttgctggtg ctcttccatt tcgccatttt
    29821 tcgttacagt caaaatctaa gacaactaat ttatcttcag agactttctc taaaagaaca
    29881 aaactcccag cacgttcact atcgtattct aaataatagg cacggacatt ttcttgagta
    29941 aaataatggg tctgctacgt cgtcatcccc cctgatgccg ccaaaatcga ataataattt
    30001 ccgcgtcaaa catgtatatt tagtgttgaa tcatttgaga atatgaaaat aaaaatcttt
    30061 ttgatcaatc agttaatcaa attgaaataa cgaaaaatct gagacagaat gacgttcatt
    30121 ctgacccaga tttgattttg cacaactcaa cagtccttat tggcaaatcg ccaaaataat
    30181 gtagactaac taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt
    30241 tagcacgtct atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta
    30301 ggtgtttcca tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt
    30361 ttttcttttt ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat
    30421 gggtttgcgg gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa
    30481 ataacttagc atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg
    30541 gtgacatttc gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa
    30601 ctacgatcac agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt
    30661 ttccgacttc ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt
    30721 caattgcttc tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca
    30781 agccaatcgt acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg
    30841 caaactcgat ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg
    30901 actttgctga gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat
    30961 ataaaacttt ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga
    31021 tgaccgaaac cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa
    31081 agaatttttc tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac
    31141 ggataatgat gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga
    31201 accgttgcaa gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat
    31261 aaaaatcttc gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact
    31321 gtccatcgat acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca
    31381 ttccgaccgt tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct
    31441 ctacttgttt ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga
    31501 tacctatgcg aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa
    31561 atgtttcgac ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt
    31621 cttctccagg gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca
    31681 ttccttcata actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt
    31741 gctgttctgt catattttgc tcctttaagc ctatttttca atcctactga actctactat
    31801 aaatcagcta attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt
    31861 tgattaattc ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc
    31921 atccgttaaa cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc
    31981 atctgtacct gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg
    32041 ttgatgaaga ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat
    32101 cattactggt cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata
    32161 gattattctt ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa
    32221 gatctcaaag atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt
    32281 ggcatctggc gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat
    32341 cgaagcattt ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac
    32401 tcgagggagc atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag
    32461 ttctgatgga acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa
    32521 gtaactgtta tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc
    32581 tgctgctgct ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt
    32641 accagctggg atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac
    32701 ttcgttgatt gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac
    32761 tctacatgct tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc
    32821 aaatcctgct tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt
    32881 tcccgaggtg gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc
    32941 taattcatct ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt
    33001 catgatttga ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac
    33061 agattgttgg ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga
    33121 taattgcacc caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa
    33181 ttcacggaag acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat
    33241 cattcctgct aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt
    33301 caagtaagca gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt
    33361 ttccaaaaca gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc
    33421 atactctgga agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg
    33481 caaactagct tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg
    33541 ctctgggaag taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt
    33601 cgttgtttcg tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt
    33661 tgcttgacgt ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt
    33721 tttcaattct gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc
    33781 atcacagcgc atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat
    33841 tgatcgcaat gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga
    33901 aacgatttcg atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat
    33961 accatgcatg ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt
    34021 ctttttacct tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg
    34081 ggaaatttga tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt
    34141 atctttagag atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc
    34201 tttattcatt actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt
    34261 tggttctgca ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc
    34321 gacgtggact tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata
    34381 gctggttgtt gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc
    34441 gttttttcat caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa
    34501 cctgccggta cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca
    34561 ctcatgtaca ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt
    34621 gaagatggcc cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc
    34681 aatgtacgga cttgtcctgc ttttttgaag taagcgtcat aataacccgc gcttaaggag
    34741 aatgtaccta acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg
    34801 acatatacat catctaatga tttcacattt tcagagcgat aaccgtagcg gataccatcg
    34861 aatcgttgca aattggaact tgcttctgat gaggcaatga tataataaac agccacaccg
    34921 tattttgaat gagccaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct
    34981 gctgctttca atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta
    35041 ggtaaagcaa tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact
    35101 gaaacgcctg aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat
    35161 gcattatctt tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca
    35221 atcaaaccaa aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa
    35281 gctgctggtt ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca
    35341 gctgcaactg ctgctgcaga accaccagaa gagccaccag gtacttttgc tgggtcccaa
    35401 gcattttttg ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc
    35461 atgtttagct taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca
    35521 tcataaattg gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt
    35581 gttacgatat tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc
    35641 cctttttcat ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat
    35701 gcctcgacct caggctctgt ttctttgatt cgttcaaatg ttgtttttgt caaatcttgt
    35761 acagtgattt ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat
    35821 tctgtcatta tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt
    35881 cttctgtttc cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat
    35941 cttgtcgcat cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttccgtat
    36001 ctacttcttc cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg
    36061 caagttcttc atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt
    36121 cactaatcgc catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta
    36181 acacaagagt gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc
    36241 attcttctac tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt
    36301 cgattcctaa ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga
    36361 tatccgtttt tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt
    36421 ttgcttcttc acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa
    36481 aaggagactc gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc
    36541 ctgcttgttt taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta
    36601 cactgtcggc aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt
    36661 tactcaatgt ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga
    36721 catgtcggat tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga
    36781 ttgctgtcaa aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt
    36841 cttctgtcaa tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt
    36901 ctagtacgcg cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca
    36961 aaccttcttt catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat
    37021 ccaaatggac aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc
    37081 tgtctttagg tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt
    37141 tataaatcag aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat
    37201 gcaggctggc acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg
    37261 gcgttactac ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt
    37321 cttctggcgg aaacttgtaa gctgctgccc atctcggtgc tttgatagta aaaccaagtt
    37381 gatcttgtag cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat
    37441 ccacacgttt gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata
    37501 gacgtttttc ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact
    37561 gggtttttgc ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc
    37621 ttttcgctgt gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat
    37681 tcgcaaagat atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt
    37741 ttggcatgaa acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga
    37801 ccgaccggac agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag
    37861 tcgcacctct cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt
    37921 ttagttcaca gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag
    37981 ctatcagctc ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga
    38041 ctttttcaaa accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga
    38101 tcaaatcagg atattgttcc tcgattgcta ctaattctgc gtattcttta tcataaacat
    38161 agtcttccac tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg
    38221 tacgaagttc ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt
    38281 accctccact actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct
    38341 tgacttggga aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact
    38401 gttcctagac cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc
    38461 cctccagtag cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct
    38521 gtttttttag cgaatacagg cgttttttta ggcgtaggac gcatgccttc gatttccagt
    38581 aactcctgat cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat
    38641 aatgttctgg agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca
    38701 tatgcgagac ggcgttcttc ctccagttcg ctttcttcca tcaatgctcg agataaagga
    38761 aaaaccccct cttctagacc aatcaggaat acaactggaa attctaatcc tttggctgca
    38821 tgcaaagtca tcaatgtcac ttgggaagca tcttcttcta aattgtcaat gtcggaaaca
    38881 agtgccagat catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca
    38941 ttttgctgtt cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt
    39001 tcgatgcgtg cttgtgcttc taatgtattt tggattttta agtcttctag atatccgctg
    39061 cgatccaaaa cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact
    39121 tcttggatca tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc
    39181 agatccacat tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt
    39241 agtttttcga tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa
    39301 ctgattgaat cttgaggatt taccagcaca ttcaaatacg ctaaaatatc tttgatttct
    39361 ttacgatcgt agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga
    39421 gtttcttcca ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa
    39481 ttccgatgat tgcttcgaat ctcttcttgc atccggtcta cgataaaacg ggtttcgtct
    39541 cgttcattat ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag
    39601 ttttttggtt ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt
    39661 ttcgtggagc gatagttttg ttctagcaaa attactgcag catctggata atctttttca
    39721 aaatccaaga tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct
    39781 cccacgacgc acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg
    39841 tgatttgtat cttggtactc atctacatga atataatgga atttgttttg ataatacgtg
    39901 agtgaatcag gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagccc
    39961 atacattgat tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct
    40021 tcgtaataac tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct
    40081 tgagagattg ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct
    40141 tttagtatcc gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg
    40201 ttatacccga taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc
    40261 gatacccaga catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct
    40321 tttgcagcct tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc
    40381 tcaatcaaat aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc
    40441 attagcagta atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg
    40501 tttaataatt cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat
    40561 tatagcattt tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat
    40621 ggatttttcc ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga
    40681 atggaaaaaa aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa
    40741 ggaatatttg ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa
    40801 aagctaagcg atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta
    40861 attggcctag ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat
    40921 gaaccggata tcaagggaag cgggattcca caagtagtgg gacagcttcg cggggaatta
    40981 tcaatgaact ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt
    41041 gcgggccttt ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa
    41101 ggagctggac aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt
    41161 gcaagtagcg gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta
    41221 gaagaaatcc atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc
    41281 actgctaact tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac
    41341 cttccttctt tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc
    41401 atcttaggtt ttatttatca gaatgtcttg ctggctttgc caaaatttta caaccgattg
    41461 cctttaccag cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat
    41521 ttatggccta gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc
    41581 ttgccaatca ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct
    41641 tacggtgggg gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc
    41701 ggtagctttt atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat
    41761 tttgtcgtta ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca
    41821 attattttag tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct
    41881 gctcttgttg cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta
    41941 ttggaacgtc tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt
    42001 gattttccag taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg
    42061 cctaaaaata tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt
    42121 gatacgatca tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca
    42181 agaatcaagc aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa
    42241 cgaacatgga aaaactattt tacaacaact attcatctac actacttgat tctatatgat
    42301 tctataaaaa aagaagaggc tgggaaaacc cagcctcttc ttttttattt ctatgcttct
    42361 gctactgcag gagcttttct caataaacca taaatcacac cagatacgac tgctccgata
    42421 gcaataaaca ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgccg
    42481 tgaggagcca gtaatttgat tccgaaagct ccgactaatc cgccagttaa agcagaacca
    42541 ataataaaac ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc
    42601 gtgacaaacg atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg
    42661 aatttattct taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca
    42721 gccataacag aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct
    42781 gtaccaaaca cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca
    42841 gctaataatg caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc
    42901 aatgcatcat tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc
    42961 agtaagccaa acactggata aaagaggatc gttttaattc catccaatga ttttggtaag
    43021 ttcttgaata atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt
    43081 gcacctaaga atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc
    43141 aaaccagggc ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa
    43201 ccaaatgcag cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga
    43261 tttgataatt gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata
    43321 gcgattcctc caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg
    43381 taaattcttt gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca
    43441 tcaccatgga atactggtgc agtaccacta agggctagat tgatcaactc ttctggttta
    43501 cggataccat cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct
    43561 acttttttgt ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat
    43621 cggtttttga ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc
    43681 gcttttttct tcaaagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct
    43741 gtaacggcaa caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct
    43801 tgttctgctt tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact
    43861 tcttctggtg tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga
    43921 gatagtgctg ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg
    43981 aaaaacagat aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt
    44041 gcgaataaaa ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca
    44101 tcaccaagac ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg
    44161 atatcggaaa tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt
    44221 ttatcagtcg cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc
    44281 atgattatcc tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat
    44341 caatcaattc gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc
    44401 cccatttaaa ggcttcgatt ggatctttcg tacggctgta agccccaata aagccagcaa
    44461 tcattgaatc ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat
    44521 aagttccttg ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct
    44581 gtgccccttc agctagtaat tttttcccat acggaatgat ttcttctaca gattggaagg
    44641 ttgtgttgta aagctcagct aattcgtgat tgtttggttt gatcaacaac ggtttcttaa
    44701 caagtgcatt ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc
    44761 gaatgatatc aatcagttct tgataaaatc cttttcgcag gctagctggc gcgcttcctg
    44821 acaatacgac gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt
    44881 cttcatctga aatagatggg cctaagccat tgatctcagt ttcagtgtct gattttagtt
    44941 tgatattgat tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt
    45001 caagccactt cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt
    45061 gagaatcgat ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga
    45121 agtcttcctt cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat
    45181 caattgatgg attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt
    45241 ttcacggaat tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc
    45301 caaaggtgca acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa
    45361 tgtctcttcg gaatttttca tggctaaacg tttaacagct gcctcttctg gatccggagt
    45421 cgtgaatcct tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa
    45481 attttttagt tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt
    45541 tccacctaaa ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga
    45601 atttgtcact actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga
    45661 gccagcgtct aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat
    45721 ttgctgtttt tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa
    45781 taattgctct ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc
    45841 ttgtaaatca cgtcttatcg ttgattcaga agcattcaaa aggtttacaa gatcttgtga
    45901 tttcacgatt ttctgctgtt caagcaagtc taggattttt tgtctgcgtt cctctgtaag
    45961 cattttcacg atcacctcaa tacaaataat agcatatttt ttttctacta gcaatataaa
    46021 tcagtcaaaa acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcag
    46081 aaagactggt tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg
    46141 cttcttgttt ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa
    46201 taaagtccca tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta
    46261 ggaacaaaaa agagacagac ggataataat gatgccggaa ccattattcg ataatagagt
    46321 tgtttatcca ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg
    46381 gtaatctaaa aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact
    46441 tcgccgcttt ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt
    46501 taacggtaat tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc
    46561 ttgatatttt tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc
    46621 ttcgattcca ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgtga
    46681 tcgattctcg tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct
    46741 ttctttataa tctccttgtt ggatatcata actttttgtt acaaaaaatg aagcattctt
    46801 tttaggaaca ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt
    46861 gtaaatgtat tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg
    46921 atcaaaccca agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca
    46981 gttaaagggg tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt
    47041 ttctacttgt tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact
    47101 ataatacatt tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg
    47161 aaattggttg caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc
    47221 gatttcatcc tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat
    47281 aaactcgcta taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat
    47341 gaagtctcga atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat
    47401 caataattga ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa
    47461 ccaactttcg tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata
    47521 cggatccgct tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa
    47581 aatagcccaa tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat
    47641 agtcatcaat aatttatctt cgccaatcat tttctcacct ctttcaaatc tttttataat
    47701 ttaattataa ccaatgataa agaaaaacta aaactttatg tcttagaaac caatttggac
    47761 gattacatga tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt
    47821 gaacgtacag ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca
    47881 gttgcaccaa aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa
    47941 aaagacaaga aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg
    48001 aaagagtttg actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg
    48061 ctgcccacgc ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat
    48121 tgcgatcaaa atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag
    48181 ggatcttatc tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt
    48241 gatacatctg gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg
    48301 cacgtagctg gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct
    48361 cagttttgga tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct
    48421 cgatcaaata aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat
    48481 tctttcgatc aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca
    48541 gagctatttc tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa
    48601 tttcagcttg atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg
    48661 gctgtcgcaa aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc
    48721 tctgaatctt tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata
    48781 atcacttttt cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct
    48841 tcaatgatgg aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg
    48901 gctctcaacg cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga
    48961 tattgtttga ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc
    49021 aatttctcta aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat
    49081 tttagtaaat cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg
    49141 ttttgtgtac caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg
    49201 ccatcaaatg caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct
    49261 tgatgtggat gtttacgtcc gccctgaggt ggcacacttg caacagttcc ttctagaatt
    49321 ttcagcaagg cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg
    49381 cttttacgcg caattttatc gatctcatca atatagatga tccctttttc tgcaagttcc
    49441 acattgtaat cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca
    49501 taaccagctt ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt
    49561 gctaatgttt gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg
    49621 cttttttgca gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag
    49681 tgattgtata cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta
    49741 ttcaatactt caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct
    49801 tcataaaatt cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag
    49861 acccctggac cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag
    49921 cgtacggtct cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa
    49981 agtatgcaag aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa
    50041 aaagaaaaag tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa
    50101 caaaaaataa ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt
    50161 tctagaagta gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc
    50221 gctgtacctg tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct
    50281 tctgtcaaca cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg
    50341 atttctgcat tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg
    50401 atcacaagat ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct
    50461 tcttctgtag aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg
    50521 ttgttcaaga attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat
    50581 tcaacgattt ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc
    50641 gctgcttttt cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat
    50701 gttgatactt cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt
    50761 gcttttactt catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct
    50821 tgataatctt ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact
    50881 aattgatctt caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg
    50941 ccttttccgc catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta
    51001 tcgccatttt cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca
    51061 cgtttgatac gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact
    51121 agatctttat attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc
    51181 cagtcttgac ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg
    51241 ccagcttctt tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca
    51301 tataaagctt cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg
    51361 aatccaggta cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg
    51421 atttcgtctt gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat
    51481 gttgcagtca tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc
    51541 atgcatacct ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga
    51601 atccttgttt ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc
    51661 atttgctgca aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct
    51721 tcatacatcg tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct
    51781 tcgatgtatg tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttctttt
    51841 aacacggaac taagcagcgc atcttcattc ccgtaacgat ctgaaaatac acataattgc
    51901 tggtaacttg cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt
    51961 tcttcaatcg tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt
    52021 aattttgccc ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg
    52081 ataaactcat gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt
    52141 tccaacgaag gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt
    52201 tgtccggata attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca
    52261 taaaaatctg tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac
    52321 aagtcaaaat aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt
    52381 gcttgcttca atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta
    52441 ttagcctcaa agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga
    52501 tattgctggt ttgctagtgc ttgttgtgcc actcgcatta aattctcata tttttctgga
    52561 aaatcaatcg gcttcacgca gtgtcctcct cttgctcata ttcagctcat gttcaatagt
    52621 agcaaaacaa aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt
    52681 ttagatctga cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg
    52741 ttgacttcct ggttgaacgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa
    52801 aaatcgccca gatgttgctt tttctgatta aagactgctg gaagataccc taacatcagc
    52861 aaaggaaatt ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta
    52921 agttcttctt catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttgg
    52981 ccatgattga atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat
    53041 ccgtagagac tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca
    53101 agtgttaaac gcgtaatagc tccgatacac aaaagatcga ccaagaaggc aaacattcgg
    53161 ataaaaaaac ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt
    53221 gtgtccgtat actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc
    53281 tctctttcaa aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc
    53341 tgctgttgct tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact
    53401 cacctccgta ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg
    53461 ataagatctg actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta
    53521 accatgtact agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa
    53581 gctgttgttc ctttcgtata gcttttaaag catcttcagg aaatcccaat tcatcgacta
    53641 aacctacttc ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt
    53701 cttcttcaga tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt
    53761 cgatatatgc ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca
    53821 tatctttcaa cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc
    53881 ctgaataatt caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg
    53941 caaagatttt atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca
    54001 tgctgacata cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt
    54061 ccgcactttc gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg
    54121 ttggatcttc ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag
    54181 aagcaaataa acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga
    54241 ttttttgcgt actgtctccc tcttccaaca catttggagc tagttcttca tccccatata
    54301 accaactgtt caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa
    54361 ctaacgaaac cacaaataat cctgcagcaa tcagaactgc tgcccaacgt cttttattca
    54421 ttctttctcc tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag
    54481 tgtcgaaccg ctctgctttt tcttcccgcg catacccgga aaacgactct tttgttaatt
    54541 catcttctac cgtaaactca cgagcttgag caacttccaa ggcatcaggt gcgatttctt
    54601 ggatgctatc ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg
    54661 cttcgaattt ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat
    54721 ccatttttac tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg
    54781 atagataaaa acccattatt ttttgacata aaaaggacat ttgacaaaga atttgatata
    54841 taccaattta ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt
    54901 taaatgtttc cagataaaaa acaaaaagga ggatagttat accttttagg atagcgccag
    54961 gtctgtgtaa acagatgacg aggagagggt ttatcgaaag attcggcgga tggccctagg
    55021 gactgcactc tacagaaaat ccacaaaaaa tgtctgcaaa gataaaacaa aaggattttc
    55081 ctgcagctgg aagcattcat acgaattcat tatagaaagt aggatgtttt ttatgtgcgg
    55141 aattgttgga atgattggat taaaaaatgt aacaccagga ttgattgacg gtctagaaaa
    55201 attagaatac cgtggttatg attcagctgg tatctttgtc tcagatggca caactgatta
    55261 tctggtcaaa gcacaaggca gaattcaaaa tttgaaaaac aaaataaata ttgatactac
    55321 aggaaatata ggtattggtc atacacgatg ggcaactcac gggcaacctt ctgaagaaaa
    55381 cgcccatcca catacttccc aaagtggacg cttcgtgctc gttcacaacg gcgtaatcga
    55441 aaactttgaa gaacttaaaa ttgcttattt agcaaatgac cactttattg gtgagaccga
    55501 tactgagatt atcgctcatc taattgaaac tttcgcgaag gatactacaa cgcaagaggc
    55561 gtttttaaaa gctttgcggg tcatcaaagg ttcttacgct ttcgctttga ttgatcggac
    55621 agcacctgat gttatttacg tcgctaaaaa taaaagtcca ctattaatcg gactcggcga
    55681 tggattcaat gtgattgcca gcgatgcaat ggctatgctt gctcatacga aggaattcgt
    55741 tgagattgaa gatgaagaga tggttaccgt cacatcagaa aaagttatta ttcaaaattt
    55801 tgcaggtgac atcgtagaac gttcttcatt cgaagcacaa gtagatgctt cagatatcga
    55861 gaaaggtacc tatccttttt atatgctgaa agaaatcgac gaacagccta ttatcatgcg
    55921 tcgtatcgct caaaaatacg taacagaaga caatcgtgtc tctcttgatc aaaagctggt
    55981 cgatacattg tctgatagcg atcgaatcta tatcgttgct tgcggaacta gttaccatgc
    56041 ggggttagca ggtaaacaga ctttggaaaa attgacacag attcctgttg aggttcattt
    56101 agccagtgaa tttggctata acacacctct tctttcaaaa aaaccattct ttattttctt
    56161 gagtcaaagt ggcgaaacag cagacagccg ccaagtgctg gtaaaaatca accgtctcgg
    56221 ctacccttca cttacgatta caaatgttgc tggttctact ctttcgcggg aagcatcctt
    56281 tacactgcta ttgcatgctg gacccgaaat cgcagtagca tcaacgaaag cttatactgc
    56341 acaaatagct gtactaactt tattagccaa agctatcggt gataaaaaag aatttgaaac
    56401 ttctcttgta ttcgatatca ctcatgaatt gagtttagtt gctaatgcga tggaatcggt
    56461 catcgcccaa aaagattatt tagaagagtt ggcagaagta tatctcagcg atacaagaaa
    56521 tgccttttac attggacgtg gtgctgacta caacgtttct cttgaagctg ctttgaaatt
    56581 gaaagaaatc agttatatcc aggcagaagg ttttgccgct ggcgaattga aacatggaac
    56641 gattgctttg atcgaagaag gaacaccagt gatcggaatc atcagtgaag aagtgactgg
    56701 tgcgcatact cgaggaaacc tgaaagaagt cgaaagccgt ggcgctaaaa cactagttat
    56761 tgtctcagag ggattagaaa aggaaagtga ccagctggtg ctaccaactg tccaccctta
    56821 tctaactact ctaaccacag tcgtaccgac tcaattactt gcatattacg caacgctatt
    56881 acggggattc gacgttgaca aaccacgtaa tttagcgaaa tcagtgacag tagaataata
    56941 aaagaacaag gaccagtgtc agacatctga cactggtcct tgttctttta ttttttatga
    57001 aaatatctct taatccagtc cgatttcttc tttgactact gccgcgattt tatcgacata
    57061 gtaattaact ttctcatcag taggcgcttc tgccatcact cgaagtaatg gttctgtacc
    57121 ggaaggacga actaggattc ttccttctga tcccatttca gcttctgcct cttcaatcac
    57181 ttttttgatt gccggaacat ccatcgcacc gtttttatca cttacgcgga tattcactaa
    57241 tttttgcgga tagattgtta cctctgctgc aagctctgat aatttcttac ctgtctgttt
    57301 catgatattc agtaactgaa ttcctgaaag catcccatct ccagttgtgt taaaatctaa
    57361 gaaaatcatg tgcccagact gctcgccgcc aaagttataa tcgtttttgc gcatttcttc
    57421 tacaacgtaa cgatcaccaa cttgtgtaac gacatctttc aaaccgattc cttccaccgc
    57481 tttgtggaat cctaagttac tcatgacagt cgtaacgatc gtatcttttt tcaatcgatt
    57541 tttttctgcc aagtatttag cacagataaa catgatttta tcaccgtcga caatgtttcc
    57601 aagttcatcc accgcaataa tacgatcgcc atcgccatcg aaagctagtc cagcatctgc
    57661 tcctttttca acgaccatct cagctaaacg ttctggatgg gtagagccta cgccgtcatt
    57721 gatatttaac ccgtctggat ttgtgcccat tgtataaaaa tctgtttcaa gatcggcaaa
    57781 caaacgatta acacttgttg aagttgctcc gtttgctgca tcgacacaaa tggtcaaacc
    57841 ggaaaggtca ccgttgatcg tttgtacaag gaattgagaa tatttcaata agccttctgg
    57901 aaattcttct acagttccca atccttcagc tgatggacga ggcaattcat ccacttcagc
    57961 atctaataat gcttcaattt ctagctcttg gtcatctact agtttaaaac catctgcacc
    58021 gaaaaatttg attccattat cttgtgctgg attatgagaa gcagaaatca tgacccctgc
    58081 gcttgctttt tgcaaacgtg tcagataagc aacacctggt gtagagatca cacctagctg
    58141 gaacacttcg atacccaccg ataaaagtcc tgaaatcagc gcttcttcta acatttgacc
    58201 tgagattctt gtatcccgcc ctactaacac gcgtgggcgt tttccttctt cttcatgctg
    58261 gcttaggaca taacctccgc accgtcccag cttaaatgca agttctggcg taagttcctt
    58321 gttggcttca ccgcgtacgc cgtctgttcc aaaatattta cccatagttg taaaattact
    58381 cctttaactt aattttctga ggaatttgtt ctgctcattt gtgttgattc gcttgtttct
    58441 gatgtttctt ctgtacttgt ggtcgagctg cttgtcccag attccgaact ggaagaaatg
    58501 gttgttgtcg atggttccgt tcctgaatca gcagatgaaa tacttctact cgtacttgta
    58561 ttttcttgtg tccgactgct cgtcgaagca gagctactgc ttgacgtttg caacacgggt
    58621 gtaatctcca cactaactga ttcgggcttg atacttaacc cctcttctac tggtatttca
    58681 attttacgag ttgttcgatg attgatacct gagacattga tcggtacagc aatactgtca
    58741 ccgatcgatg caagcaaatc gctagagccg cttacttctg cttccagttt tgaaaaactg
    58801 aaatcatagc tttctacccc ggcagctggt gttccttgct gtatcccata aagtcgtacc
    58861 gacttgcttg gcttgatcga atcagctctc actgttactt gcactggatc agagacgata
    58921 cttaatactt cccctgctgc attcagcgcc tgtattggga cctcactatt aatcccatca
    58981 tctgtgacca tcgaagcgtc cacatcagct actactcgtt tgatttctgc caatgttttg
    59041 tcacctgtag tgatagagac ttttttagga ctaacggaag tatcatcaag ttcatatcca
    59101 gatggtgtga acgttgaagg aatcaacgtt tccacatcga aatcttttat tacctttttc
    59161 tcaaccgtta ctgtaatagt cgatggttcg atctttgctg tgacagcact gctcaaattt
    59221 tgaattttta gcggaacttc atgtgttcct tcgcccagct tagtgatatc tgctgtgacg
    59281 cggaacatcc gtgtatcttc gtttgcctct gcattcaact gaactcggtt tgcactggaa
    59341 agtttgacag tcactgcatt ttcatatcca tggatatagt agcgctttga atcataagaa
    59401 atcttgatcg gcacccccgt aactgtttga ttatacgctt catttccaga aagcgtattt
    59461 ggaacggact ggccatttgc attgaagtac agcgcaatac tgaacagcaa tgcaataaaa
    59521 ctgtaaagaa tgcttgtccg tttctctttt gagatcattt gcgatcccct cccttagtca
    59581 taccgtctag gaaagattga atcacgtttt tcttgttttt tgttttctct tcagcaatta
    59641 gttctctacg caagattgcc aaatattctt gctgggataa gccagccatc agttcattat
    59701 ctaacgtgat gctgacgtcc ccggtttctt cagagacaac gatggtaatc gcgtcactga
    59761 cttcgcttat accgacagct gcccggtgtc gagtcccgaa ttctttaggg atcaacatac
    59821 tttctgatag aggaagatag gcgcttgcta ctgcgatctt tccttctttt acaataactg
    59881 caccgtcatg cagcggtgta ttaggaataa agatattgat cagcagctcc ccagtgatat
    59941 ctgcatctaa agcaatccct gtctcaatat actcatctaa tccagtatga cgttcgatag
    60001 tgatcaacgc accgattttt cgcttggaca tatattggat ggctttgtca aaagacaaga
    60061 tcatcttctc atcttcctgc tgttcgcttt ttgattgttt gaaaagcgaa ctgcgtccaa
    60121 gatgttccag tcctctccgg atttccggct gaaaaatcac gatagcagct atcaccccgt
    60181 acgtaatgac ttggttcatc agccaagaca aggtgtgcag accaatgatt tccgctacga
    60241 ttcggataac aataaaaata gctacacctt tcagaagctg aatcgctttt gtgcctcgca
    60301 gcagttggat cagtttgtat acaagatacc agacaaccag aatatcaagt atgttcacca
    60361 aaaaattcag agagaacaag tcaccggaaa acatttgctg ccaatagtcc aaattaaaaa
    60421 gttccccgat ttgaaatgac ataaaaagcc tctcttctct tttgagattt cctctctagt
    60481 atatcatatg ttttaatttt agaggctgat atgctcgtat ttttcttgag aaaaacgcat
    60541 aattttcaag aaaattgcaa gtatgcgttt tatttttctc tgcaataaat atttttaaac
    60601 ttcagagaat tattcattat attttttctg ttatttttcc tttttttctt ttgtagcttg
    60661 ttccattttt ttacgtcgtt ctgctctggc agctcttcta gcagctcttc tttcttctgc
    60721 ttcaaggtcc gtcgtttttt cttttctagt cttaacgggt acatcgatag attcctctgg
    60781 ttcaagtcgt ttcttgattt tttctaattc tcccgtcagt gcagcatagt tgtaaaaacg
    60841 tgttttagcg tcgtggacag tcttttcaaa taaagctttt gcaagatttg gatttgcgtt
    60901 atctagcgag gaaaagcgaa cttgtttcct catgaaatca ggcatagcag agaaatcagg
    60961 ttttttgtag tccaaagtca ttgggttctt gtttttttcg accattgtag ggttatatcg
    61021 atataatgac caataaccag aagaaacagc ttcttttgct tctttaagcg attctttcat
    61081 tccgccaagc aagccatgtg tgatacaagg cgtataggca ataatcagag aaggaccagg
    61141 atacttttct gcttcttcaa atgccttgat cgtttgcatt tgattggcac ctgaagcaat
    61201 ttgcgccaca taaacatttc catatgtcat cgccatcatt cctagatctt tctttgaagc
    61261 atactttcca ctagccgaaa atttagcgat tgccgaagct ggtgttgctt ttgaggtttg
    61321 accgccagta ttggaataga cttcgttatc caaaacaagg atattcacgt ctgctccgct
    61381 ggcaagtaca tgatcgatcc cgccaaaacc aatgtcgtaa gcccatccgt ctccaccaat
    61441 catccattgg ctgtttttta cgaatagatc ctttctcttg tatatatcct ccagttcagg
    61501 gaaaattgat cgttcgcttt cgatcgcagc ttgcagtttt gctgctcttt gctgcgttcc
    61561 ttcactctca aacatgtgta ctaaccagtc ttccatcaat tctcgtagtt cttctgatac
    61621 ttttggcaat acttctttga ttgaacttgc caaagcctcg cgacgagtct gtgccgctag
    61681 aagcatacca taaccaaatt cagcattatc ttccaataaa gaatttgacc atgcaggccc
    61741 ttgaccacat tcattggtcg tataaggaga agcaggagaa gcaccgcccc aaatagaaga
    61801 acagcctgtc gcattcgcga tcatcattcg atcaccgaac atttgtgtca ataattttac
    61861 ataaggtgtt tcgccacagc ctgagcaagc gcccgagaat tcaagaagcg gttgattgaa
    61921 ttgtgtagac aagacagtat tctttccttt gactggattt gctttttgtc ttaatgtcat
    61981 tgcaaaagcc caattcacag cttgttcttt ctgttcttca taaggcttca tcactaaagc
    62041 tttttctttt gcgggacaag cctctacaca cagaccacaa cctgtacagt cttccactga
    62101 aacttggata cggtatttta cgccgtctgc gcctcgcatt tctctcacga taaatccttc
    62161 tggcgcttct tccatttcct cttcatctgc taaaaatgga cggatggcag catgaggaca
    62221 aacaaaggca cattcattac acatcgtaca gcgatcacta atccactcag gtacttctaa
    62281 agcgacgccc cgcttttcca tagaagccgt tcctaaaggc atttcgccag ttgtcattcc
    62341 atttgctaca agtgtaccaa cagagagttg atttccttcc tgtgcattca ctggttcaag
    62401 tatttcttgt atataaccag tgttcctttt attgattttt tcaggcatct ccaacgttct
    62461 ccaatggtct gggatcgcga cttgatgaag cagttcggtc gtccgatcga ttgcttgtat
    62521 gtttttttct acgatagcca ttgatttatg tccatagctt ttcagggctt cttcttttag
    62581 cagcggaagc acctcatcaa aaggaatgat gtcagctaat ttaaaaaaag ccgtttccat
    62641 tgccgtattg atccggcgtc ccaaaccgac ttcttgggcc aatctcatgg cattgatcgt
    62701 atagaatcta atgttatttt cagccaagta acgttttaat tttaagggca gatgcgtttc
    62761 taattgttcg tcgctccaaa gagtattcaa taaaaaaatg ccacctggct tcaatccttt
    62821 gaccaagtca tagctatgca ggtaagctgg tgtgtgacag gcaacaaggt ccgcatgctc
    62881 gacaagatac gctgaacgta tcggcgtatc tccaaaacga agatgagaga cagtcagacc
    62941 gccagatttt ttcgaatcat aataaaaata gccttgcgca tatttatcgg tgtgatctcc
    63001 aataatcttg atagctgatt tatttgctcc aactgttccg tcagatccaa atccccaaaa
    63061 cttggcctgg aatgtttgcg gttctgtcaa atccagactt tcctttggtt ccaaagattg
    63121 ataagtcaca tcatccacga tccctatggt aaaccgtttt ttgcgtatgc ttgggtcttt
    63181 tttcaattca tcaaaaactg ctgagatttg gtcgggagtc acatctttag accccaatcc
    63241 gtagcgacca ccaataacag ccgggcgaag ttcagaatca tataacgcac tttgaacgtc
    63301 taataagaga ggttctccac ctgcccctgg ttctttactt cgatcaagaa cagcaattgt
    63361 ttttactgta tgaggcaact tttgcacgaa tgtttccact ggaaaaggac gataaagatg
    63421 gatattcaaa aaacctgttt tccgtccgtt tgcattcaag taatcaatcg tttgttcaat
    63481 cgtctgtgca actgatccca tagaaacaat gacttcttcc gcatcgtctg ctccgtaata
    63541 agtcaccaag tcataagaag ttcctcgtaa tcggttgatc tctttcatat atttttgaac
    63601 gatttcaggt aatttatcat aataggggtt gatcgtttcc cgttgttgaa aatggatgtc
    63661 tggattctgg ttcgtaccac taacagtcgg atgattggga ttcatccctc gtttacgaaa
    63721 tgaagctaat ttctcctgat tgatcagagg agctaattct tcatattcca aaacttcgat
    63781 tttttgaatc tcgtgactcg tacggaatcc atcaaagaaa ttcaaaaaag ggacttctcc
    63841 ttcaatagaa gcaagatggg caacaggtgc taaatccatc acttcttgta cactgctttc
    63901 agctaacata gcaaatcctg tttgtcttgc agccatcacg tctccgtgat ctccgaaaat
    63961 attcaacgca tttgtcgtca ctgcccgact agcaacgtgg aaaacacttg gcagtagttc
    64021 cccagcaatc ttgtacatat tcggtatcat caaaagcagc ccttgtgaag cggtatatgt
    64081 agttgtcagt gcaccagttt tcaatgatcc atggaccaca ccagctgctc ctgcttcgga
    64141 ttgcatttct actactttta ctggttgacc gaatacgttt tcttttcctg ctgctgacca
    64201 ttgatctact aattcagcca tggtcgaact gggtgttatt ggatatattg cagcaatctc
    64261 ggtaaatgca taagaaatat atgcggctgc cgtattgcca tccattgttt tcatttttcg
    64321 catgattcat catccttgtt catattctct cttattatct gttccattat aacgtaaaac
    64381 atgccatttt tttcttttat ttataaaaat attttacatg tatctatttg aattggtcat
    64441 ctaattttta gacaaacagt ctaaatcgtt gccttttttt gtcagacatg tataaactat
    64501 aagcgaaaga ggtgttttaa catggatata tcagtgattg atgcaacgaa aacaaataca
    64561 caaaaaggaa tcctttatgg ttcatcgaat gctcctaaaa aaatggtcga attcatcaac
    64621 ttagcttgtc cgtattgccg acaatggttt gaagaatctt atgagctatt agaagaagca
    64681 gtccaaagcg ggcaattgca gcgagtgatc aaattgttcg ataaagaaaa agaaagctta
    64741 cagcgaggga acgtgatgca ccggtatctc acaatcagcg atggccaaaa agcgatcaaa
    64801 gagatcaaac aaatattcga tactcaagac gagtggaaac atctttctct ccaagaagta
    64861 gcggattttg cagtagataa actaaagctg acagaacaaa aagacgaaca gctgagccaa
    64921 gctgtcatca acgaagctga gcaagcacat attcgatttg ttccaactgt catcttgggt
    64981 aaagaaatct ttgatgaatc tatttcaata gaggaattaa aagaattgat ccaaacaaaa
    65041 taaaaaaata aggagcgtgg gacaaaagta aagaacactt ttgtctcacg ctctaaacac
    65101 gtataaacgg cggaagcaga agcaactcct tcttatttct tggagttaaa cgcttctgtc
    65161 ccagcctcct tattccgaat aaatggtgtc caaaagcttg catctgccag attatctcat
    65221 ttcttatgac aagctaagca aattatctcc accaaataat ttattcatat ttttgacttg
    65281 cgcatactaa ctaattctta aattttcata caaaatttct caatttccct taacgagtaa
    65341 tatttatgta cggtgattct cactagtatc ccaatcactt tttaagttat cccgatttca
    65401 attctacttc aaaaatagtt gcttttatgt atgctgttag ttgattagat ggtcatttgt
    65461 tgagctaggt cgtttatttt aaacaagttg tttctttagc ttatacctat ctcgtctacc
    65521 aaacgcaaga tggcaaacac aaatgcatac gcatctgtat t
//
LOCUS       DAFEIE010000007        60914 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFEIE010000007
VERSION     DAFEIE010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.007"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(34..615)
                     /locus_tag="LP345_000535"
     CDS             complement(34..615)
                     /locus_tag="LP345_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1759342.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(748..1431)
                     /gene="rpiA"
                     /locus_tag="LP345_000536"
     CDS             complement(748..1431)
                     /gene="rpiA"
                     /locus_tag="LP345_000536"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBL1759343.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            1750..2163
                     /gene="rpsL"
                     /locus_tag="LP345_000537"
     CDS             1750..2163
                     /gene="rpsL"
                     /locus_tag="LP345_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBL1759344.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            2247..2717
                     /gene="rpsG"
                     /locus_tag="LP345_000538"
     CDS             2247..2717
                     /gene="rpsG"
                     /locus_tag="LP345_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBL1759345.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            2811..4898
                     /gene="fusA"
                     /locus_tag="LP345_000539"
     CDS             2811..4898
                     /gene="fusA"
                     /locus_tag="LP345_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL1759346.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            5070..6257
                     /gene="tuf"
                     /locus_tag="LP345_000540"
     CDS             5070..6257
                     /gene="tuf"
                     /locus_tag="LP345_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL1759347.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            6664..6972
                     /gene="rpsJ"
                     /locus_tag="LP345_000541"
     CDS             6664..6972
                     /gene="rpsJ"
                     /locus_tag="LP345_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBL1759348.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            7003..7632
                     /gene="rplC"
                     /locus_tag="LP345_000542"
     CDS             7003..7632
                     /gene="rplC"
                     /locus_tag="LP345_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBL1759349.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            7660..8283
                     /gene="rplD"
                     /locus_tag="LP345_000543"
     CDS             7660..8283
                     /gene="rplD"
                     /locus_tag="LP345_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBL1759350.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            8283..8573
                     /gene="rplW"
                     /locus_tag="LP345_000544"
     CDS             8283..8573
                     /gene="rplW"
                     /locus_tag="LP345_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBL1759351.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            8612..9445
                     /gene="rplB"
                     /locus_tag="LP345_000545"
     CDS             8612..9445
                     /gene="rplB"
                     /locus_tag="LP345_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBL1759352.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            9488..9766
                     /gene="rpsS"
                     /locus_tag="LP345_000546"
     CDS             9488..9766
                     /gene="rpsS"
                     /locus_tag="LP345_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBL1759353.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            9789..10136
                     /gene="rplV"
                     /locus_tag="LP345_000547"
     CDS             9789..10136
                     /gene="rplV"
                     /locus_tag="LP345_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBL1759354.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            10150..10806
                     /gene="rpsC"
                     /locus_tag="LP345_000548"
     CDS             10150..10806
                     /gene="rpsC"
                     /locus_tag="LP345_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBL1759355.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            10809..11243
                     /gene="rplP"
                     /locus_tag="LP345_000549"
     CDS             10809..11243
                     /gene="rplP"
                     /locus_tag="LP345_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBL1759356.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            11233..11421
                     /gene="rpmC"
                     /locus_tag="LP345_000550"
     CDS             11233..11421
                     /gene="rpmC"
                     /locus_tag="LP345_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBL1759357.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            11446..11712
                     /gene="rpsQ"
                     /locus_tag="LP345_000551"
     CDS             11446..11712
                     /gene="rpsQ"
                     /locus_tag="LP345_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBL1759358.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            11770..12138
                     /gene="rplN"
                     /locus_tag="LP345_000552"
     CDS             11770..12138
                     /gene="rplN"
                     /locus_tag="LP345_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBL1759359.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            12175..12483
                     /gene="rplX"
                     /locus_tag="LP345_000553"
     CDS             12175..12483
                     /gene="rplX"
                     /locus_tag="LP345_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBL1759360.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            12511..13050
                     /gene="rplE"
                     /locus_tag="LP345_000554"
     CDS             12511..13050
                     /gene="rplE"
                     /locus_tag="LP345_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBL1759361.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            13069..13254
                     /locus_tag="LP345_000555"
     CDS             13069..13254
                     /locus_tag="LP345_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBL1759362.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            13290..13688
                     /gene="rpsH"
                     /locus_tag="LP345_000556"
     CDS             13290..13688
                     /gene="rpsH"
                     /locus_tag="LP345_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBL1759363.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            13720..14256
                     /gene="rplF"
                     /locus_tag="LP345_000557"
     CDS             13720..14256
                     /gene="rplF"
                     /locus_tag="LP345_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBL1759364.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            14417..14773
                     /gene="rplR"
                     /locus_tag="LP345_000558"
     CDS             14417..14773
                     /gene="rplR"
                     /locus_tag="LP345_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBL1759365.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            14794..15294
                     /gene="rpsE"
                     /locus_tag="LP345_000559"
     CDS             14794..15294
                     /gene="rpsE"
                     /locus_tag="LP345_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBL1759366.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            15309..15488
                     /gene="rpmD"
                     /locus_tag="LP345_000560"
     CDS             15309..15488
                     /gene="rpmD"
                     /locus_tag="LP345_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBL1759367.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            15532..15972
                     /gene="rplO"
                     /locus_tag="LP345_000561"
     CDS             15532..15972
                     /gene="rplO"
                     /locus_tag="LP345_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBL1759368.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            15972..17267
                     /gene="secY"
                     /locus_tag="LP345_000562"
     CDS             15972..17267
                     /gene="secY"
                     /locus_tag="LP345_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBL1759369.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            17329..17976
                     /locus_tag="LP345_000563"
     CDS             17329..17976
                     /locus_tag="LP345_000563"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBL1759370.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            18167..18385
                     /gene="infA"
                     /locus_tag="LP345_000564"
     CDS             18167..18385
                     /gene="infA"
                     /locus_tag="LP345_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBL1759371.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            18418..18534
                     /gene="rpmJ"
                     /locus_tag="LP345_000565"
     CDS             18418..18534
                     /gene="rpmJ"
                     /locus_tag="LP345_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBL1759372.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            18552..18917
                     /gene="rpsM"
                     /locus_tag="LP345_000566"
     CDS             18552..18917
                     /gene="rpsM"
                     /locus_tag="LP345_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBL1759373.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            18945..19334
                     /gene="rpsK"
                     /locus_tag="LP345_000567"
     CDS             18945..19334
                     /gene="rpsK"
                     /locus_tag="LP345_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBL1759374.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            19414..20352
                     /locus_tag="LP345_000568"
     CDS             19414..20352
                     /locus_tag="LP345_000568"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBL1759375.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            20380..20760
                     /gene="rplQ"
                     /locus_tag="LP345_000569"
     CDS             20380..20760
                     /gene="rplQ"
                     /locus_tag="LP345_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBL1759376.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            21032..21871
                     /locus_tag="LP345_000570"
     CDS             21032..21871
                     /locus_tag="LP345_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1759377.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            21847..22716
                     /locus_tag="LP345_000571"
     CDS             21847..22716
                     /locus_tag="LP345_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1759378.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            22706..23503
                     /locus_tag="LP345_000572"
     CDS             22706..23503
                     /locus_tag="LP345_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL1759379.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            23706..24452
                     /gene="truA"
                     /locus_tag="LP345_000573"
     CDS             23706..24452
                     /gene="truA"
                     /locus_tag="LP345_000573"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL1759380.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(24785..27454)
                     /locus_tag="LP345_000574"
     CDS             complement(24785..27454)
                     /locus_tag="LP345_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBL1759381.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(27692..27880)
                     /locus_tag="LP345_000575"
     CDS             complement(27692..27880)
                     /locus_tag="LP345_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBL1759382.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            28150..28512
                     /locus_tag="LP345_000576"
     CDS             28150..28512
                     /locus_tag="LP345_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1759383.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            28564..30246
                     /locus_tag="LP345_000577"
     CDS             28564..30246
                     /locus_tag="LP345_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBL1759384.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            30363..32399
                     /gene="recG"
                     /locus_tag="LP345_000578"
     CDS             30363..32399
                     /gene="recG"
                     /locus_tag="LP345_000578"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBL1759385.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            32448..33449
                     /gene="plsX"
                     /locus_tag="LP345_000579"
     CDS             32448..33449
                     /gene="plsX"
                     /locus_tag="LP345_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBL1759386.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            33571..33813
                     /gene="acpP"
                     /locus_tag="LP345_000580"
     CDS             33571..33813
                     /gene="acpP"
                     /locus_tag="LP345_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL1759387.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            34081..35085
                     /locus_tag="LP345_000581"
     CDS             34081..35085
                     /locus_tag="LP345_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759388.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            35086..36030
                     /locus_tag="LP345_000582"
     CDS             35086..36030
                     /locus_tag="LP345_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759389.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            36030..36992
                     /locus_tag="LP345_000583"
     CDS             36030..36992
                     /locus_tag="LP345_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759390.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            37019..37933
                     /locus_tag="LP345_000584"
     CDS             37019..37933
                     /locus_tag="LP345_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759391.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            37959..39740
                     /locus_tag="LP345_000585"
     CDS             37959..39740
                     /locus_tag="LP345_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1759392.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            40088..40774
                     /locus_tag="LP345_000586"
     CDS             40088..40774
                     /locus_tag="LP345_000586"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBL1759393.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            40794..44375
                     /gene="smc"
                     /locus_tag="LP345_000587"
     CDS             40794..44375
                     /gene="smc"
                     /locus_tag="LP345_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBL1759394.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            44384..45193
                     /locus_tag="LP345_000588"
     CDS             44384..45193
                     /locus_tag="LP345_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1759395.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            45204..46202
                     /gene="ftsY"
                     /locus_tag="LP345_000589"
     CDS             45204..46202
                     /gene="ftsY"
                     /locus_tag="LP345_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBL1759396.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            46389..48656
                     /gene="gshAB"
                     /locus_tag="LP345_000590"
     CDS             46389..48656
                     /gene="gshAB"
                     /locus_tag="LP345_000590"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBL1759397.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(48745..49197)
                     /locus_tag="LP345_000591"
     CDS             complement(48745..49197)
                     /locus_tag="LP345_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBL1759398.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKSNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            49347..50297
                     /locus_tag="LP345_000592"
     CDS             49347..50297
                     /locus_tag="LP345_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL1759399.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGMIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            50290..51249
                     /locus_tag="LP345_000593"
     CDS             50290..51249
                     /locus_tag="LP345_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL1759400.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            51246..52001
                     /locus_tag="LP345_000594"
     CDS             51246..52001
                     /locus_tag="LP345_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1759401.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            52024..52977
                     /locus_tag="LP345_000595"
     CDS             52024..52977
                     /locus_tag="LP345_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1759402.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(53621..53917)
                     /locus_tag="LP345_000596"
     CDS             complement(53621..53917)
                     /locus_tag="LP345_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBL1759403.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            54272..54628
                     /locus_tag="LP345_000597"
     CDS             54272..54628
                     /locus_tag="LP345_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1759404.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            54638..55537
                     /locus_tag="LP345_000598"
     CDS             54638..55537
                     /locus_tag="LP345_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBL1759405.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            56053..56784
                     /locus_tag="LP345_000599"
     CDS             56053..56784
                     /locus_tag="LP345_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL1759406.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            56929..58956
                     /locus_tag="LP345_000600"
     CDS             56929..58956
                     /locus_tag="LP345_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL1759407.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            59064..60161
                     /locus_tag="LP345_000601"
     CDS             59064..60161
                     /locus_tag="LP345_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL1759408.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            60468..>60914
                     /locus_tag="LP345_000602"
     CDS             60468..>60914
                     /locus_tag="LP345_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759409.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        20167 a        10903 c        13007 g        16837 t
ORIGIN      
        1 aacagtgccc acgcaactgt tcgtttttag gtattagatg cataattgct cgatttcttt
       61 ttcaggtaaa ttgatatatt tataacatgt tccaactgaa acaccgcatt ttgaagaaat
      121 aaattggatc gtttcttttt tttcataata gagacgtcgg atttttttga tcgtttttgc
      181 atcgattttt ggtcttccgc cgatttttcc ttttttacga gcttcatcta atccaactaa
      241 tgtacgttct ttgatcaatg cgcactccat gtttgctagg ttttccatta attggaaata
      301 gatttttccc atttcgcgcg tatcgattcc ttcatcaaga ctaatcaagt gcagcccgcg
      361 atctttgaat aattgcgtga gttctgttaa ttgccgcgta gatttgccta atcgatgaag
      421 ttggcaaatg actagtgcat cgccttgttg catgtcagcg atcactgact ccaaatgaac
      481 agcagtagaa tcattttgtt ccacttcata tgtctcatgg aaaatttctt gacaaccaaa
      541 gtcagataat tgatcaacct gagttgttaa atcaacgtca tttatggttg tgcgtgcata
      601 accaataatt ttcatggtga ttcctttcta gcagtgattt tctaactgga tataacagta
      661 aaaatgtagc ataaagtacg tcaaaaagat agttttttcg caaattttcc gctgtctttt
      721 tttattggat gatcaagcag tttttcttta tttacgacgg attgcgtcaa gaatctcaac
      781 gcctttttct gagccgacaa ctactttaga aaccatgttt aggaaaagcc catgttctac
      841 taccccaaca agttcatcta aataggtagc taagctttct ggctgttcga tgacttctag
      901 atgcagatca atgatgtaat gaccaccatc tgtggttaag acttctccgt tttcgtctgt
      961 acgcaagacg ggttggaatc ttttttcttc aaaaatatga agtagctgtt gggagccata
     1021 agggatcact tcaactggga gtgggaactt cccaagttta tcgactaatt tagaagaatc
     1081 aacgatccaa atcgtttctt ttgagtacgt agcgactatt ttctcgaaaa gcaaagcagc
     1141 gccgccgcct ttgatccctt gaaaatcagc actgatttca tcagcaccgt ctattgtcaa
     1201 atcgactacg gggacttcat caatactctt taacggtatt cctaattttt ccgcttgttc
     1261 ttttgtcgca tttgaagtag taactcctgt gatacgtaaa ccttcttcac gcatacggcg
     1321 accaatctct tctaccatat aataggcggt tgaaccggtc ccgagaccta cgatcatccc
     1381 gtcctttacg aatttcgcgg cttcaatgcc agctaattgt tttaaattca tctttgcgtc
     1441 cacctttttt tagtttgagc atcgtgcttt cctcactatt ttagcgtgat ttacggtaaa
     1501 aagataccat tcttttttat tccaataaag ctttttcaaa aaaaattgca tctcttgttg
     1561 acatgttttt tcattcgtga tattctaaca aaggtgcttt atctacaggt ttctgtgaag
     1621 aaacgtgctg actgtttatc aaagcatatt tgataaggat gcagacattg catttatttt
     1681 ttatcacaaa aaaagaacca cctggatgtg tggaactaga cgcaaatcgt gggaaggagg
     1741 aaacaaggaa tgcctacaat taaccaatta gtacgtaaac ctcgtaaatc aaaggtggaa
     1801 aaatctaatt cacctgcttt gaacaaagga tataacagct ttaagaaaac tcaaactaac
     1861 gtaaactcac ctcaaaaacg tggggtagca actcgtgtgg gtacaatgac acctaaaaaa
     1921 ccgaactcag ctttacgtaa atatgcacgt gttcgtttgt caaacttaat tgaagttact
     1981 gcttatatcc cagggattgg tcataactta caagaacaca gtgttgtatt attacgcggt
     2041 ggtcgtgtaa aagacttacc aggggtacgt taccatatcg ttcgcggtgc tttagatact
     2101 gctggtgtta acgaccgtaa acaaagccgt tctaaatacg gaactaaaaa acctaaagct
     2161 taattttaat tattaaacaa atgaaacttg cttctactat atagaagtaa ttactatgaa
     2221 caatatttcg gaaggaggag ttacggatgc cacgtaaagg tcctgttgca aaacgtgatg
     2281 ttttaccaga tcctatttat aactcaaaat tagtaactcg cttgatcaac cgtgtaatgg
     2341 ttgacggaaa acgcgggatt gcagctaaca ttatctataa tgcctttgac ttgatcaaag
     2401 aatctacagg taacgatcca ttagaagtgt ttgaacaagc aatgaaaaac gttcaacctg
     2461 ttcttgaagt taaagcacgt cgtgttgggg gttcaaacta ccaagtacca gttgaagttc
     2521 gccctgaacg ccgcgttact ctaggtcttc gttgggtagt aaactacgct cgcttgcgcg
     2581 gtgaacacac aatggaagaa cgcttagcaa aagaaatcat ggatgctgca aacaacacag
     2641 gtgcttctgt taaaaaacgt gaagacactc ataaaatggc tgatgccaac cgtgcgtttg
     2701 ctcactatcg ctggtaagat tctctctgtt tggtcggctt ttataagtcg acctcagata
     2761 gtgtccttat ttttagcaac tagatagtaa agagaggaga aacaaggaga atgaccagag
     2821 aattttcttt acaaaacact cgtaatatcg gtatcatggc ccacatcgat gctggtaaaa
     2881 cgactgctac tgaacgtatc ttgtactata ctggtaaaat ccataaaatt ggtgaaactc
     2941 atgaaggagc ttcacaaatg gactggatgg aacaagaaca agaacgtggt attacgatca
     3001 cttctgctgc tactacagca caatggaagg gtcaccgaat caacatcatc gacacaccag
     3061 gacacgtaga cttcacagtt gaagttgaac gttcattgcg tgtacttgat ggtgctgtaa
     3121 ctgttcttga tgcacaatca ggtgttgaac ctcaaactga aacagtttgg cgtcaagcaa
     3181 caacttatgg tgtacctcgt atcgtatttg caaacaaaat ggacaagatc ggtgctgact
     3241 tcttatattc agtatcaact ttacatgacc gtttgcaagc aaacgctcac ccaatccaat
     3301 taccaattgg tgcggaagac gacttcacag gaattatcga ccttgtaaca atgaaggctg
     3361 aaatgtatac aaacgatctt ggaacagaga tcgaagaaac agaaattcct gaagaatacc
     3421 gcgaattagc tgaagaatgg cgcgaaaaat tggttgaagc tgtagctgaa actgatgaag
     3481 aacttacttt gaaatactta gaaggtgaag aaatcactga agctgagtta aaagaaggta
     3541 tccgccgcgc aacagttaac gtagaattct acccagtact atgtggttca gcatttaaga
     3601 acaaaggggt tcaattacta ttggacgctg ttcttgatta cttgccatca ccgttagata
     3661 tcccagctat caaagggatt gaccctaaaa ctgatgaaga agtagaacgt cctgcagacg
     3721 acagcgctcc tttctcagct ttagcattta aagttatgac tgacccattc gtaggtcgtt
     3781 taactttctt ccgtgtgtac tctggtgttt tacaatcagg ttcatacgta caaaacgcaa
     3841 caaaaggcaa acgtgaacgt gttggtcgta tcctacagat gcatgccaac tctcgttcag
     3901 aaatctctga agtttacgct ggagatatcg ctgctgctgt tggtttgaaa gacacaacta
     3961 ctggggacac actatgtgat gaaaagagtc tagttattct tgaatccatg gaattcccag
     4021 aaccagttat ccaagtcgct attgaaccta aatcaaaagc tgaccaagat aaaatgggtg
     4081 tggctttaca aaaactatct gaagaagatc ctactttccg tgctgaaaca aacgtggaaa
     4141 caggcgaaac aatcatcgct ggtatgggtg aacttcactt agatatcatc gttgaccgta
     4201 tgcgtcgtga attcaaagtt gaagctaacg taggtgcgcc tcaagtatct taccgtgaaa
     4261 ctttccgtgc tggcactcaa gccgaaggta agtttgtacg tcagtctggt ggtaaaggtc
     4321 aatacggtca cgtatggatt gaatttacac caaatgaaga aggtgctggt ttcgaatttg
     4381 aaaatgcgat cgtcggtggg gttgttcctc gtgaatacat tccagctgtt gaaactggtt
     4441 tgaaagatgc tatggaaaat ggtgtcttag ctggctatcc attagtagat atcaaagcta
     4501 aactttacga tggttcatac catgatgtcg attcaaatga aactgccttc cgtgttgctg
     4561 cttctatggc attacgtgca gcagctaaga aagctaatcc agtaatcctt gaaccaatca
     4621 tggctgtaga agttgttatc cctgaagatt atttaggtga tgttatgggt cacgtaactg
     4681 ctcgtcgtgg acgtgttgaa ggtatggaag ctcgcgctgg cggccaacaa gttgttcgtg
     4741 cgatggttcc acttgctgaa atgtttggtt atgctacaac tcttcgttct gctactcaag
     4801 gtcgtggtac atttacaatg acatttgacc actacgaaga tgtaccaaaa tcagtacaag
     4861 aagaaatcat taagaaaaac ggcggaaaag ctgaataatt tcttaaaacc ggatagtcct
     4921 gcaaagagat tatccaaaga gactatattt ttaatatagt ttcgtgtaaa ataattatcg
     4981 atgatatggg catgtggtgt accttgtgta catcatatac ctatcagaca aataaaaaat
     5041 atattgtatt tttaggagga cattttaaaa tggcaaaaga aaaatttgac cgttctaaac
     5101 cacacgttaa cattggtact atcggacacg ttgaccatgg taaaactaca ttaacagctg
     5161 caatcacaac tgtactatct aagaaaaacg gcggccaagc tatggcttac gatcaaatcg
     5221 atggtgctcc agaagaacgc gaacgcggaa tcacaatctc aacagctcac gttgagtatg
     5281 aaacagatac acgccactac gctcacgttg actgcccagg acacgcggat tacgttaaaa
     5341 acatgatcac tggtgctgct caaatggacg gagctatctt ggtagtttct gctgctgacg
     5401 gcccaatgcc tcaaactcgt gaacacatcc tattgtctcg tcaagttggt gttccttaca
     5461 tcgttgtatt cttgaacaaa gtagacatgg ttgatgacga agaattacta gaattagttg
     5521 aaatggaagt tcgtgaccta ttaacagaat acgaattccc tggtgacgat gttcctgtag
     5581 ttgctggatc agctttgaaa gctctagaag gcgacgcttc atacgaagaa aaaattcttg
     5641 aattaatggc tgcagttgac gaatacatcc caactccaga acgtgacaac gacaaaccat
     5701 tcatgatgcc agttgaagac gtgttctcaa ttactggacg tggtactgtt gctacaggtc
     5761 gtgttgaacg tggacaagtt cgcgttggtg acgaagttga agttgttggt attgctgaag
     5821 aaacttcaaa aacaacagtt actggtgttg aaatgttccg taaattgtta gactacgctg
     5881 aagctggaga caacattggt gctttactac gtggtgttgc acgtgaagac atccaacgtg
     5941 gacaagtttt agctaaacca ggtacaatca cacctcatac aaaattctct gcagaagtat
     6001 acgtgttgac aaaagaagaa ggtggacgtc atactccatt cttcactaac taccgtccac
     6061 aattctactt ccgtacaact gacgtaacag gtgttgttga attaccagaa ggaactgaaa
     6121 tggttatgcc tggcgacaac gtaacaatgg aagttgaatt aatccaccca atcgctatcg
     6181 aaaacggtac taaattctca atccgtgaag gcggacgtac agttggtgcc ggtgtcgtta
     6241 cagaaatcaa agcttaattc acttaagttt taaagtaaag caacatttat tcggacgtaa
     6301 tcgctcggaa cgaaggtctt aggatctttg ttccgagctt ttttatttat tgcaggatca
     6361 ggaaaaaaga caggagtatt ataaatagaa gaaacacgaa ataaaagagt cagtattttc
     6421 taaatgaaac tttatgaaaa caaaatgttt tttacaagaa aaagccttgc tttgtgagtt
     6481 tatatatatt ataatgacaa aggtgcgttt actttagtga attgcacaga cgtaatcaga
     6541 atgatttcgt cggctaagaa acgagaggtt gcgacacgcc cggacgcttt gccacgaacg
     6601 agcgtgacgg aaattttcgt ggagctatgt ctacttttca aaataggcga aggagggaac
     6661 aagatggcaa aacaaaaaat tcgtatccgt ttaaaagcgt atgaacaccg tattttagat
     6721 caatcagcgg ataaaatcgt ggaaactgca aaaagaactg gagctagcgt gtctggtcca
     6781 attccattac caactgaacg cagtctttac acaatcatcc gtgcgactca taaatacaaa
     6841 gattcacgcg aacaattcga aatgcgtaca cacaaacgtc ttatcgacat tgtgaaccca
     6901 acaccaaaaa ctgttgatgc tttgatgaag ctagacttac catctggtgt aaacatcgaa
     6961 atcaaattat aaaactaaaa caaaaataat ggaggtgtac tcatgaccaa aggaatctta
     7021 gggaaaaaag tgggaatgac acaaatcttc actgaatctg gtgaattaat tccagtaact
     7081 gttgtagaag ctactccaaa cgtagtacta caagtgaaaa caatggaaac ggatggctac
     7141 gaagctattc aagttggtta ccaagatatg cgtgaagttt tatcaaacaa acctgcgaaa
     7201 ggtcatgttg caaaagcaaa cacggctcct aagcgcttca ttcgtgaatt caaaaatgtt
     7261 gagctaggag aatatgaagt aggaaaagaa attacagtag atgttttcca agcaggagac
     7321 attattgatg taacaggtac tacgaaaggt aaaggattcc aaggggttat caaacgccac
     7381 ggacaaagcc gcggaccaat ggctcacggt tctcgttacc atcgtcgtcc tgggtcaatg
     7441 ggtccagttg cacctaaccg tgtatttaaa aacaaacgtc ttgctggccg tatgggtggc
     7501 aaccgcgtaa ctatccaaaa cttggaagtt gtacgtgtcg atgcagaaag aaatgttatc
     7561 ttgatcaaag gtaatgttcc tggagctaaa aaatctttaa ttactatcaa atcagctgtg
     7621 aaagctaaat aattgtagga agaaaggagg aactaaggaa tgccgaatgt agcattattc
     7681 aaacaagatg gaagccaaaa cggtgaaatc acacttaacg aagaaatctt cggaattgaa
     7741 cctaatgaaa gtgttgttta cgatgcaatc gtaatgcaac gtgcgtcatt aagacaagga
     7801 acacacgcgg ttaaaaaccg tagcgctgtt cgcggcggcg gacgtaaacc atggcgtcaa
     7861 aaaggaacag gtcgtgcacg tcaaggatct atccgctcac cacaatggcg tggaggtggc
     7921 gtagtctttg gaccaacacc acgttcttac agctacaaac ttcctaaaaa agttcgtcgt
     7981 ttagcaatga aatctgtatt gtcagaaaaa gttgctgaaa acaacttggt agcaatcgaa
     8041 ggcttgaact tcgacgcacc aaaaacaaaa gaattcaaac aagttcttgc taacttatct
     8101 atcgactcta aagtattggt tgttctagaa aaaggtaacg actttgctgc tttatcagca
     8161 cgtaacttac caaacgtttc tgtagtaact tctgataatg tgagtgtgct agacgttgta
     8221 tcaaatacaa aagtgttagc aacacaaact gctcttactc aaattgagga ggtgcttgca
     8281 taatgaactt actagacgta atcaaacgcc cagtgatcac tgaaaaatca atgcttgcca
     8341 tggatgacaa gaaatacact tttgaagtgg acactcgcgc aaacaaaact ttagtaaaac
     8401 aagcggtaga agctgctttt gacgttaaag tcaaaaacgt gaacatcgtg aacgtacgtg
     8461 cgaaattcaa acgtatgggc aaatatgcag gatatacaaa aaaacgtcgc aaagcgatcg
     8521 ttacattgac tgaagattca aaagaaatcc aattattcga agctgctgaa taagcactaa
     8581 tagataactc attaaattag gagggaaaaa cgtggcgatt aaaaagtaca aacctacctc
     8641 aaatggtcgt cgtaacatga caggttctga ttttgctgaa atcacaacat caacacctga
     8701 aaaatcattg ttacaaccat tgaaaaacca tgctggacgt aacaacaacg gccgcatcac
     8761 tgtacgtcat caaggtggcg gacacaaacg ccaatatcgc gtgatcgact tcaaacgtaa
     8821 caaagataac gttgttgcaa ctgttcaaac gatcgaatat gatccaaacc gttcagctaa
     8881 catcgcgtta gtacactatg aagatggagt gaaagcttac atcttagcac ctaaaggact
     8941 agaagtgggt atgaaacttg tttcaggtcc agaagcagat atcaaagtcg gaaatgctct
     9001 tccattagaa aacattccag ttggtactgt tatccacaac attgaaatga aacctggtaa
     9061 aggtggacaa ttgatccgtt ctgctggtac aagtgctcaa gtacttggta aagaaggcaa
     9121 atacgtattg atccgcttga actctggtga agttcgtatg atcttagctg catgccgtgc
     9181 tacaatcggt tctgtaggta acgaacaaca cgaattaatc aacatcggta aagctggacg
     9241 ctctcgttgg atgcgtaaac gcccaactgt acgtggtagc gtaatgaacc ctaatgatca
     9301 cccacacggt ggtggtgaag gtaaagctcc tatcggacgt aaagcaccag tttctccttg
     9361 gggtcaacca gctcttggtt acaaaactcg taacaaaaaa gctaaatcag acaaacttat
     9421 tgttcgtcgt cgcaaaaata aataattact ttgaccatgt gtcgcacatt ttgagaggag
     9481 gttcaccatg ggtcgtagtt taaagaaagg accttttgtc gatgagcatt taatgaaaaa
     9541 agttgaagct caagcagggg ttgaaaagaa aaaagttatc aaaacttggt cacgccgttc
     9601 aacagttttc ccaagttttg ttggatatac catcgcagtt tatgatggac gtaaacatgt
     9661 accagtttac atccaagaag acatggtagg acacaaatta ggtgaatttg cacctacaag
     9721 aacttatcgt ggacatgctg ctgacgataa gaaaacgaaa cgctaatttg aggggaggat
     9781 aaatccaaat ggcagaacaa atcacatcag ctaaagcaac tgcaaaaaca gttcgcactt
     9841 cacctcgaaa agcccgttta gtaattgacc ttatcagagg taaaagtgtc gcagatgcaa
     9901 tttcaatctt gaaattcaca ccaaacaaat ctgctggaat cattgaaaaa gtattgatgt
     9961 cagcagttgc gaatgcagaa aataactttg acttagatgt tgaaaacttg gtagtaagcg
    10021 aagcttttgt taacgaagga cctacaatga aacgtttccg tcctcgtgca aaaggatcag
    10081 cttctccaat caacaaacgt acaagtcata tcacggtagt cgtatcagaa aaataaggag
    10141 ggataatcag tgggtcaaaa agtacatcca attggaatgc gtgtaggcat catccgcgac
    10201 tgggatgcta aatggtatgc tgaaaaagag tatgctgagt tcttacacga agatttaaga
    10261 atccgtaaat ttatttcaac taaacttgct gatgctgctg tatcaacagt tgaaatcgaa
    10321 cgcgcaacag gtcgcgtaaa catttcaatt cacacagcta aaccaggtat ggttattggt
    10381 aaaggcggtt ctgaagtcga aagcctaaga aaagaattaa acaaattaac tggtaaaaga
    10441 atccatatca atatcgtgga aatcaaaaaa ccagatctag atgcaaaatt agtaggtgaa
    10501 ggaatcgcac gtcaattaga aaaccgtgtt gctttccgtc gcgctcaaaa acaagccatc
    10561 caacgctcaa tgcgtgctgg cgctcaaggg atcaaaactc aagtatctgg tcgtctaaac
    10621 ggagcagata tcgctcgttc agaaggatac tcagaaggaa ctgttcctct tcatacttta
    10681 cgtgcggaca ttgattacgc atgggaagaa gcagatacaa catacggaaa actaggagtt
    10741 aaagtgtgga tctatcgtgg agaaattctt ccaactaaaa aaaacactga gaaaggaggg
    10801 aaataatcat gttagtacct aaacgtgtaa aacaccgtcg tgaattccgc ggaaaaatgc
    10861 gcggggaagc taaaggcgga aaagaagtag cattcggtga atacggtttg caagctgttg
    10921 attcacattg gatcacaaac cgccaaatcg aagctgctcg tatcgcaatg actcgttaca
    10981 tgaaacgtgg tgggaaagta tggattaaaa ttttccctca caaatcttat actgccaaag
    11041 caattggggt acgtatgggt tctggtaaag gggcacctga aggatgggtt gcaccagtaa
    11101 aacgtggtaa aatcatgttt gaaatcgcag gcgttcctga agaagtagct cgtgaagcgt
    11161 tacgtctagc ttctcacaaa ttaccaatga aaactaagat cgtaaaacgt gaggaaatgg
    11221 gtggtgaatc gaatgaaggt taaagaaatc agagaattaa ccactgccga aatgcttgat
    11281 caagaaaaac aattaaaaga agaattgttt aatcttagat tccaattagc aacaggtcaa
    11341 ttagaaaaca ctgcacgtat taaagaagta cgtaaatcga ttgcacgcat caaaactgtg
    11401 ttgcgtgaac aagctaagta attatggaag gaggccatta agcgtatgac tgaaggaaga
    11461 aatcaacgca aagtttatca aggtcgcgtg gtttcagaca aaatggataa aacaattacc
    11521 gttgctgtcg aaacaaagaa aaaccaccct atctatggca aacgcatgaa ctattctaag
    11581 aaatacaaag tgcatgatga aaacaacaca gcaaaagttg gcgacatcgt gagaattatg
    11641 gaaactcgtc cattatcagc tacaaaacgt ttccgtttgt tggaagtagt cgaagaagca
    11701 gttattatct aataacacga gattttccta tatagattga atgcaaaatc tgaaaggagg
    11761 atacacaacg tgatccaagc agaaagtcgt ttaaaagtcg ctgataactc aggcgcacgt
    11821 gaaattttga cgatcaaagt ccttggtgga tctggtcgta aaactgctaa catcggtgat
    11881 gtgatcgttg ctacggttaa acaagcaacg ccaggtgggg ttgtcaaaaa aggtgacgtc
    11941 gttaaagccg ttatcgttcg aacaaaatca ggagctcgtc gtacagacgg ttcatatatt
    12001 aaatttgatg aaaatgctgc agtgattatt cgtgatgata aaagccctcg tggaacacgt
    12061 atctttgggc cagttgcacg tgaactacgt gaaaacaact tcatgaagat cgtttcacta
    12121 gcaccagaag ttttataatc ttgagacact tatcaaagga ggtgcgaaac agttatgttt
    12181 gttaaaaaag gcgataaagt taaagttatc actggaaaag acaaaaacaa agaaggcgtt
    12241 gtactagcag cgttcccgaa aaaagataaa gttattgtcg aaggtgtaaa tgtcgttaaa
    12301 aaacaccaaa aaccttctca agctgctcct caaggtggaa ttgttgagat ggaagcgcca
    12361 attcatgttt ctaacgtgat ggtggttgac tctactggtg tagctggccg agttggctac
    12421 aaagaagtag acggcaaaaa agtccgtgtt tctaaaaaaa ccggtgaagt tttagataaa
    12481 taaaagttta aggaaggagg gtcttactga atgaaccgcc taaaagaaaa atatcttaaa
    12541 gaagtaactc catcattgat ggaaaaattt aactatagct ctgttatgca aacacctaaa
    12601 gttgaaaaaa tcgtcatcaa catgggtgtt ggtgatgcgg tatcaaacgc taaaaactta
    12661 gataaagcag ttgaagaatt aactttgatc actggtcaaa aaccaatgat tacaaaagct
    12721 aaaaaatcaa tcgctggatt ccgtttacgt gaaggaatgc caattggtgc aaaagttaca
    12781 ttgcgcggag aaagaatgta cgaattctta gacaaattgg tttctgtttc actaccacgt
    12841 gtacgtgact tccatggtgt aagtaaaaaa gcctttgacg gtcgtggaaa ctatacttta
    12901 ggtattaaag aacaattgat cttcccagaa gtagattatg atttagtaga taaagtacgt
    12961 ggtatggaca tcgttattgt aacaacagca aactctgatg aagaatctcg tgagttgttg
    13021 acacaattag gcatgccatt ccaaaaataa ttaaaggagg cgaactacgt ggctaaaaaa
    13081 tcaatgattg ctaaaaacaa acgtcctgca aaattttcaa cacaagctta tactcgttgc
    13141 gaacgttgcg gacgtccaca ttcagtttat cgtaagttcc atctttgccg tatttgcttc
    13201 cgcgaacttg cctataaagg tcaaattccc ggcgtgaaga aagctagctg gtaaaaagta
    13261 aattcgcata agaaggaggt aaaagatcaa tggtcatgac agatccaatt gcagattttc
    13321 taactcgtat ccgtaacgca aacatggtta aacatgagtc tttagaagta cctgcatcaa
    13381 aaattaaacg tgacatcgct gaaatcttga aacgtgaagg tttcgttcgt gatgttgaat
    13441 acatcgaaga tgacaaacaa ggcgtgatcc gtgttttcct aaaatttggt aaaaacggcg
    13501 aacgtgttat cacaaactta aaacgtatct ctaaaccagg tttgcgtgct tatgtcaaag
    13561 ctgacgaagt accaaaagta ttgaacggtt taggtatcgc aatcatttcg acttctgaag
    13621 gtgttgtcac tgataaagaa gctcgtgaaa aaaatatcgg cggcgaagtt atcgcttacg
    13681 tatggtaatc aagtagaatc tacaaggagg tgtctttaag tgagccgtat cggaaataaa
    13741 gtcgttgtta tccctgaagg agtaacagtt actcaagacg gaaacaacgt tacagttaaa
    13801 ggaccaaaag gtgaattgac tcgtactttt tcagcagata tcaaaatgaa tatcgaagga
    13861 aacgaagtaa ctttcactcg tccaaacgac agtaaagaaa tgaaaacaat tcatggaaca
    13921 actcgtgcga acttcaacaa catggttgta ggtgtcagcg aaggtttcca aaaagcgtta
    13981 gaactaatcg gggttgggta ccgtgcacaa ttacaaggat caaaacttgt attgaacgtt
    14041 ggttactcac atccagtaga aatcacacca ccagctggag taactgttga agtaccagct
    14101 aacacacaag taattgttaa aggtgcgaac aaagaagaag ttggcgaatt agctgcaaac
    14161 attcgtggaa ctcgtcctcc agaaccttat aaaggtaaag gtattcgtta tgttggcgaa
    14221 tatgtacgcc gtaaagaagg taaaactggt aaataatcgt ttagaaaaat tgcatagaag
    14281 ccagcagcag gaaaaaggca tttggctgaa gtttaccttc aaaaaaatac atttttactt
    14341 gtgccgcagc ttctattttt cgaaacgtat ttactgcttg aaatagtagt acaataaaaa
    14401 taaagaggtg acaattgtga ttacaaaacc agataagaac aaaacacgtc aaaagagaca
    14461 tcgtcgtgta cgtaacaata tctctggtac tgctgagcgc ccacgcttga acgtttttcg
    14521 ttctaacaaa aacatctacg ctcaaattat tgatgacgta gcgggtgtaa cgctagcaag
    14581 tgcctctacc ttggataaag aaatttcagg tggaacaaaa acagaagcag cacaagctgt
    14641 cggtaaacta gttgctgaac gtgcagctga aaaaggcatt aaagtagtag tctttgaccg
    14701 tggtggatac ctttaccatg gccgtgtgca agctttagct gaagctgctc gcgaaaatgg
    14761 actagaattt tagaagaagg aggaatacca ttcatggttt atatcgatcc aaaacatttg
    14821 gaattagaag accgcgttgt tgcaattaac cgtgtaacaa aagttgttaa aggtggacgt
    14881 cgtctacgtt ttgctgcttt agttgttgtc ggtgacaaaa acggacacgt agggtttggt
    14941 acaggtaaag ctcaagaagt tcctgaagca atccgtaaag caattgaaga tgcgaagaaa
    15001 aacttagttg aagtacctat ggttggttca acaatcccac acgaagtaat cggtgctttt
    15061 agtggtggta gaatcctaat gaaacctgct gtagaaggtt ctggggttgc tgctggtgga
    15121 ccagttcgtg ccgtattaga attagctggg gtagcagata tcacttctaa atctttaggc
    15181 tcaaatacac caatcaacgt tgttcgcgca acagttgaag gtttgaaaca attgaaacgt
    15241 gcagaagaag ttgcagaact tcgcggcaaa tcagttgaag aattaatcgg ataaggagga
    15301 caacaataat ggctgaatta aaagttactt taaaacgcag tattatcgga cgtcctcaaa
    15361 accaacgcga tacagttaaa gcgttaggtc ttacaaagat taacagttca gtggttaagc
    15421 cttctaatga agcaattaaa ggcatgatca atactgtttc tcacctagtg gacgttgaag
    15481 aaatttaatt tagaaaaatc ataactagaa cattaaggag gtgccaaacc tatgaaactt
    15541 catgaattaa aacctgctga aggttcacgc caagtacgta accgtgttgg tcgtggtact
    15601 tcatctggta acggaaaaac tgccggacgc ggacaaaaag gacaaaaagc tcgttcaggc
    15661 ggcggtgtgc gtttaggatt tgaaggggga caaacaccat tgttccgtcg tttaccaaaa
    15721 cgaggattca caaacgtgaa ccgtaaagac tatgcagtca ttaatcttga tgtattgaac
    15781 cgctttgaag acggagctga agtaactcct gttgctttag ttgaagctgg aatcgtgaaa
    15841 aacgaaaaag ctggaatcaa agtattagct aatggggaac taaacaagaa attaactgtg
    15901 aaagcagcaa aattctctaa agcagctcaa gaagcaattg aagcggctgg tggatcaatc
    15961 gaggtgatct aatgtttaga ctattaaaag atgcttttaa agtaaaagac attagatcga
    16021 aaatcctatt tactgtattt gtgttgtttg tatttcgcct aggtgcacat attactgtac
    16081 caggcgtaaa tgctgcttca ttgcaaaacc tttcttcttt gccatttttc aacatgttga
    16141 acttggtaag tggtagtgcg atgcaaaact tttccatttt ctcaatgggg gtttcaccat
    16201 acattactgc ttctatcgtc attcagcttc ttcaaatgga catcgtgcct cgatttgttg
    16261 aatggtcgaa acaaggggaa gttggtcgta aaaaactgaa tcaagcgact cgatatctga
    16321 cattagtatt ggcatttatc caatctgtcg gtatcactgc tggattcaat caatacgctc
    16381 aattaggttt cgtgaataat cctaacgtag caacttacgt aacgatcggt ttgattctaa
    16441 cagccggtac gatgtttgtt acttggctag gagaacagat cacagaaaaa ggtatcggaa
    16501 atggcgtatc aatgatcatt tttgcaggta tcatttctag attgcctgaa agtatcagag
    16561 aaatttatga agattacttt ataaatattg atccttcaga catatggaaa tctgctattt
    16621 ttgtggccat tttactagta gcggtcttgt tgatcgtgac attcgtaaca tttttccaac
    16681 aagctgaacg caagatcccg atccaatata cgaaacgcgt agctggcgcg cctacaagca
    16741 gctatctgcc gttgaaagta aatgcagctg gagttattcc agttatcttt gctagttcgt
    16801 ttattgctac gccaaatgct gttttacaag cattgagcgg tagattcggt tctgaaaact
    16861 ggtacaaagt gatgatggag atctttaact ataatacagc acctggtgct acgatttata
    16921 cgattctgat cgttgccttc actttcttct acgcctttgt tcaagtaaac cctgagaaat
    16981 tagcggaaaa cttgcaaaag caaggaagtt atataccaag cgtacgccct ggtaagggga
    17041 ctgaagagta tgtctcaaga ttactgatgc gtttaagtac agttggtgca gtcttccttg
    17101 gtttagtggc attgcttcca atcattgctc aaatggtttg ggatcttcca caatcaatcg
    17161 gattaggcgg tacaagctta ctgatcgtta tcggtgtagc tttagaaact gcgaaacagt
    17221 tagaaggctt aatgctgaaa cgtaaatatg ttggattcat tgagtaagaa agcgtgttga
    17281 ggtttcccct caacacacgt tctcacacat ttattaggag ggaaaacaat gaacctcatt
    17341 ttaatggggc tgccaggcgc aggtaaagga acacaagctg aaaaaatcat tgatgcttat
    17401 ggtattccgc acatctcaac aggagatatg ttccgcgcag cgatgcaaaa cgaaacagct
    17461 cttggcctgg aagcaaagtc ttatatggat aaaggtgcat tagttcctga tgaagtaaca
    17521 aatggaatcg tgaaagagcg actagctgaa ccagatacag agaaaggctt cttattagat
    17581 ggctttccac gtacgctaga tcaagcaaaa gctctggacg caatgctaaa agatttgaat
    17641 aaaaaaattg atgctgtcat cgatatccat gttggtgaag aaatcttggt cgaacgtcta
    17701 gccggccgat ttatctgcag caattgtgga gcaacttacc ataaaatttt caaccctaca
    17761 aaagttgaag acacatgtga tcgttgcggt gggcatgaat tctatcaaag agaagatgat
    17821 aaacctgaga cggttaaaaa tcgtctggct atcaacatca aaaatagtga accaatcttg
    17881 gcttattata aagaacaagg tttgctaaac actattgatg gtgctcgtga aatcgatgct
    17941 gtatttgcag atgtacaaaa aatcattgaa aaatagcacg attgcccgta gccgacttgc
    18001 attatgcagt tactcttgtc aagttcaata aattatgata gaatatgtca gtccgacttc
    18061 tagagaatcc tctagatgat ccattttgag aattttgagg tgggaactgc agtttccgcc
    18121 attttatcgt gtgaaaatgc gaaacaagta caaggaggta ctgtgcgtgg caaaagaaga
    18181 tatgattgaa gtcgaaggta cagtcgtcga aactttgccg aatgcaatgt ttaaagttga
    18241 actagaaaac ggacaccaag ttcttgctac tgtttcaggt aaaattcgta tgcattacat
    18301 ccgtatctta cctggtgaca aagtaacggt tgaattgtct ccatacgatc ttaaccgtgg
    18361 ccgtattact tatcgcttta aataattgta ctccgtaaaa ctacaggagg tattatcatg
    18421 aaagtaagac catcagtaaa accaatgtgc gaacattgta aagtaattcg tcgtaaagga
    18481 cgcgttatgg tgatttgccc agcaaatcca aaacataaac aacgtcaagg ataattggag
    18541 gtgctataaa tatggctcgt attgcaggag tagatattcc tcgtgataaa cgtgtagtag
    18601 tttcacttac ttatatctat ggtattggta acactactgc taaaaagatc ttagctgatg
    18661 ctggtgtatc tgaagatgtt cgcgttcgtg aattaacgaa tgaacaaaca gatgctatcc
    18721 gtgcagaagt agataaatta aaagttgaag gggatcttcg tcgtgaagtg aacttgaaca
    18781 tcaaacgttt gatggaaatc ggttcttacc gtggaatccg tcatcgccgt ggattgcctg
    18841 ttcgtggaca aaacacgaaa aacaatgcac gtactcgtaa aggcccagct cgcgctatcg
    18901 ctggcaagaa aaaataattc ttaagtgaag gaggttaaaa cttcatggca gcaaaaaaag
    18961 tgaatcgtaa acgccgtgtg aagaagaata tagaagcagg tattgcacat atccattcta
    19021 cattcaataa cactatcatc atgatcactg atactcacgg aaatgcatta gcgtggtcat
    19081 cagctggttc attaggtttc aaaggaagca aaaaatcaac tccttttgcc gctcaaatgg
    19141 cagcagaaac tgctacaaaa gcagcaatgg aacacggatt aaagactgtt gaagtaacag
    19201 ttaaaggacc tggttctgga cgtgaagcag caattcgttc attacaagct acaggtttag
    19261 aagtgactgc aattcgtgac gtgactccag ttcctcataa tggtgcccgc cctccaaaac
    19321 gccgtcgtgt ttaatgagtg ccgctcattt tgagttttat cagtaacgtc attgaacaag
    19381 acacttttcg ttttgaaagg ggtaaagata agaatgattg agttcgaaaa accaagaatc
    19441 gcaaaaattg atgaagaaaa agattatggc aagttcatcg ttgaacctct tgaaagaggg
    19501 tatgggacta ctttagggaa ttccctacgt cgtattttat tatcttcttt gccaggtgct
    19561 gccatcacta atattcaaat cgatggtgta ctgcatgaat tctctaccat caaaggtgtt
    19621 agagaagacg tcactcaaat catcttgaac attaaaggct tagcgctgaa aatgtatggc
    19681 caagaagaaa aaacccttga aatcgatatt accggacctg ctacagtaac tgctggcgat
    19741 attatcgttg atagtgatgt agaaattctt aacaaagata tgtacatctg tagtgtctct
    19801 gaaggagcta cgttccatgc tcgcttaaca gtgaaacctg gacgtggtta tgttcaagca
    19861 gatgaaaata aaaaagaaga tatgccaatt ggcgttcttc cagtcgattc aatctacaca
    19921 cctgttcgtc gtgtgaacta tcaagttgag aacacacgtg ttggacaccg tgaagatttt
    19981 gataaattga cgatggagat ttggacagat ggttcaattg aaccgttgga agcaatgagt
    20041 ttgtctgcga aaatcatgac tgaacatttg gatatttttg tgaacttaac tgatgaagca
    20101 aaaaatgctg aaatcatggt cgaaaaagaa gaaacacaaa aagaaaaaat gttggaaatg
    20161 acgatcgaag agttagactt gtctgttcgc tcttacaatt gtttgaaacg tgcaggaatc
    20221 aatactgtac aagaacttac aaataaatct gagcctgaaa tgatcaaagt ccgtaactta
    20281 ggacgtaaat cattagaaga agttaaagca aaattgcacg acttaggttt aggtttacgt
    20341 aaagaagatt aaaacctttt acgaaggagg gaaaccaacg tgagttatcg taaactagga
    20401 cgcacatcta gccaacgtaa agcgatgttg cgtgatttaa caactgattt attaatcaac
    20461 gaacgtattg tgactactga agctcgtgcg aaagaagttc gctcaactgc agaaaaaatg
    20521 atcactttag gtaaacgcgg agatttgcat gcacgtcgtc aagctgcggc tttcgtacgt
    20581 aatgaagttg ccagcgtgcg tgaagaaaat gaggacatcg tcattgaatc agctttacaa
    20641 aaactgttca acgatattgc acctcgttac gcagaacgtc aaggcggata cacacgcatt
    20701 ttgaagacag aaccaagacg cggtgatggt gcaccaatgg ttgtcttaga acttgtctaa
    20761 aatcacacta ataacatcac tttatagatg attcttttag agtgttatga tgttggaaga
    20821 tatttttccg agtctagctc agcgctgctc ctcaagcgaa tatcgcttgg ggagtaagca
    20881 ctcatcataa agtgtttttt tataccttca attacctgtc atgacagata tgtttgaagg
    20941 cataaaaaaa cattttaagc gagaaataat tgaaaatttt gtcttttttt gatagtgtta
    21001 gtaggaactt taggatgaag aaggagtaat catggagcca attattgaat tagaaaagat
    21061 aaattataaa taccagccag atgatcttcg ccccgcattg aaagatgtct cctttacaat
    21121 tgataaaggt gagtggatcg ctattattgg acacaatggt tcaggaaaat cgacacttgc
    21181 caaaacgatc aatggattgc ttctgccaga atcagggatc gtgaaagtgg gaaatcaaat
    21241 attggatgaa gaaaatattt ggacgatccg acagatggtt ggaatggttt ttcaaaatcc
    21301 agacaatcag tttgttggtt cgacagtaga agatgacgtt gcttttggtc ttgaaaatca
    21361 agggattccc agagaagaaa tgctagtgcg tgtgaaagat gcacttgaga aagttagaat
    21421 ggctgagttt gcttcacgcg agcctgctcg tttatcagga gggcaaaaac aacgtgttgc
    21481 cattgccggc gtggttgcct tacgacctga tatcattatt ttagatgaag caaccagtat
    21541 gctagatcca gaaggtcgtg aagaagtgat ctctacgatc aagaagatca aagaagaaag
    21601 tcaattgacc gttatatcta tcactcatga tattgatgaa gcagctaatg ccaatcggat
    21661 actagtgatg agacaaggcg aacttgtccg tgaaggtaca ccaaaagaaa ttttttctgc
    21721 tggtcctgaa ctgatcgact taggtctaga tctaccattt cctgaaaaac tgaagagcgc
    21781 actgaaagaa cgtggggttg atgtgcccag tgaatatatg acagaagaaa ggatggtgga
    21841 ttggttatgg acatccgttt tgaacaagta gacttcactt atcagccgaa tacaccattt
    21901 gaacaaagag ccttatttga catcaatatg acgatcaaag aaaacagtta tactgcatta
    21961 gtagggcata ccggaagcgg gaaatcaacc ttacttcagc atttgaatgc gcttgttaag
    22021 ccaacaagcg gtacagtcca tattggagaa cgagatattc agccggatac ggataataag
    22081 aatttaaagc ccatccgaaa aaaagttggc atcgtctttc agtttccaga agcacagcta
    22141 ttcgaagaaa cggtagcaaa agacattgct ttcggtccta aaaactttgg tgtcagcgaa
    22201 gaagaagcac tagtcctagc aaaagaaaca ttagaacaag ttgggctgga tgaaagctat
    22261 ttggaacgtt cgccatttga actttcagga gggcaaatgc gtagagtagc aatcgctggt
    22321 gtgcttgcca tgaggccgga agtacttgta ttggatgaac caacggcagg acttgatccc
    22381 cagggcagaa aagaaatgat ggagatgttt tggcgtcttc ataaggaaca gcagatcact
    22441 attgtattag ttacgcattt aatggatgat gtagccaatt ttgcagatta tgtctatgtg
    22501 ttggaaaagg gacgaatcgt taatagcggg gagccgcaag aggtctttca aaacattgaa
    22561 tggctaaaag aaaaacaact aggcgtacct actgccaccg agtttgcaga agaattaatg
    22621 gctaaaggga tgaactttgc taccttgcct ttgacagctg aagaattagc agacgctatc
    22681 gtccattatg ctggaggaaa tgcccatgat gaataaattg atatttggtc gttatatgcc
    22741 tggagattcc ttgatccatc gattggatcc ccgagctaaa ttattagcca gtttttattt
    22801 tatcggaatc atttttttag caaataattg ggaaacgtac cttttgttgg catttttcac
    22861 attactttct gtcttcttgt caaaagtaga tttgaaattt tttatccgag gcattcgccc
    22921 attgatctgg ctaatcctct tcactgtagc tttgcaggtc ttgtttacaa gtggcggaga
    22981 aacttattgg agttggggtg ttttccatat cactgaattt ggtgtgatga acggcctctt
    23041 tattttctgt cgattcgtgt tgatcatttt tatgtcgact ctactcacgc ttactacacc
    23101 gcctttggaa ttatcggatg cgattgagta cttgcttcgt ccattgaaag ccgtacggtt
    23161 cccagtccac gaaatttcat tgatgctgtc gattgctctt cgttttgtgc ctacattgat
    23221 ggacgaaaca gaaaagatca tgaacgctca gcgcgctcgc ggtgttgatt ttggtgaagg
    23281 aaacctagtt cagaaaatga aagcagtcat tcctttgctg attcctttat ttgtcagcag
    23341 cttcaaccgt gcggaagatc ttgcgactgc tatggaagca agaggctaca aaggtgggga
    23401 aggaagaacg aaatatcgtg tattgcattg gcataataga gacacgatgg ttatcattgc
    23461 ttttgtatta ttaactgtgc tactgatctt tttaagagga taaacgttca gtgggccgct
    23521 atctattctt ttcttgctga tctgtttgca agaaaggatg caagcagtgt atgacaagaa
    23581 atattagggt ctgtggcaga ctaaggtcac aggcctcttt cttttatctg aaaagaaaga
    23641 acgaaaaaat tttatagaaa aatcattatt ccagataacc ttttaggaac aaaggagaga
    23701 aaaacatggt acgttacaaa gcaatcattg cgtacgacgg aacaaatttt aatggattcc
    23761 aaaaacagcc aaatgggcgt actgttcaag aagaagtaga aaaaacatta caaaaaatgg
    23821 caaatggaaa agaaatcacg gtctttggtt cgggaaggac agatgccgga gtacatgcga
    23881 tcgggcaagt aatccatttt gattatccag aggagcgtcc gttagaacga atgcgtttcg
    23941 cgctagatac ccagtcacca gaggatattg ctgtaagaca agtagaaatt gtttcagaag
    24001 acttccacgc aagatatttg gtcaaagaaa agacgtatca atttcgagtg gatataggga
    24061 aaccacgcag tccttttcga cgccattatg caagttattt tccttaccca cttgatttgg
    24121 aaaaaattca gcgggcgctt cctgatttat tagggactca cgatttcacc tctttttgtg
    24181 catcaggaag ctcgatagag gataaaatac gtacgatcta cgaggctaag atggaggtaa
    24241 atgaaacaaa agacgaattg ttgtttacat ttaggggaaa tggcttcttg tataagatga
    24301 tacggatctt agtaggaacg cttttgaaaa ttggcaatgg ccgattgcct gaagatagta
    24361 tcccagatat tattgcgaaa aaagatcgta atgcagcagg acctacagca caccctgaag
    24421 gactttattt gtatgaagtg aaatatgaat aagaggttat gatagaagtg gtcagcttca
    24481 agaaataaga aggtatttac gaaaattact tctcaaaatt ttgcaaaatt tcggcttatt
    24541 ttcgaagaag ctacttctgg aacaccgttt aagaaagagg tcgtgagcct gtcatttaac
    24601 tctgagtcac aaagagcaat ttcaaaaaac agcttctcat ctttgatgaa tatcgtgact
    24661 tgtggacgag gcgttgataa gtgaatcatc tttttgttac ctattttttc tgtaaccaaa
    24721 aaacgatgga acgttgtttt gattgccctt ggtgcggaca gtctgaacag gttccatcgt
    24781 ttctttattt tctacgtctt cttctgtgtg tgtttcgtgg ttgttcttct attgctggat
    24841 caatcgtgcc ataaaagggg cgattgcggt caaggtacca gacataaaga ataaacaatg
    24901 caatacatag gacaaaaagg attgcaccta tcgtaaatcc ttcaggcaag taactgaaag
    24961 tgacagtatg tttacctgct ggaactttta tcatcaagaa tgcgtctttg aaattgctga
    25021 ccttgactgg tttcccatca attttagctt tccatccttt gtcataagga atagttgtca
    25081 ccaacatgga atcttcagcg gtatttacag tcccagaagc ttttctgcca gtggcttcca
    25141 tttcgacacc tttttctttg atctgattca ttgcggcttg ataggctaca acatctagac
    25201 caacgacttt aggctccatg aaacttattt ctttcgtccc ataaaaactt gcagtaaatg
    25261 tcactgttgt ctcttgagga taatagccaa gatcatagta ttgaccagaa atgttgattt
    25321 gcgtttttcg cgatgtacca ttgacagtga tcgtcgcact agaactttct aattgcgcaa
    25381 aattggttgg gaacaaactt aagtaagctt gtgtatttgc aggcacatgg acttcccaag
    25441 tgagctcttt tggctggtta tctgctgttt ctgagtaagt gacgccagtc gttgtctttg
    25501 tgatcgtcgt attcaactga ttcttcaaag taggtgtata gaatgtaaaa tactgttcat
    25561 ttagaccaga caatgtattg atcaagtttg tctgactggt caaattatct gtcactggct
    25621 gctcaacatc attaacggac aacggtgcag taaatgctag tggcaatgca ttgacattct
    25681 gatacagtgt atagtcgccg ctttgaccag cttggcggaa gccatattta ctgaacgtgc
    25741 tttcgttttt agaaatgtta tatttgattc ctgtaaaccc atccatcagc aaagtattat
    25801 tgttataacg gatattcaaa tttgtccctc ttgaacggaa acctaattta tccaggtaag
    25861 aggaagaatt acgatttctt atagaagaaa acaaactgat accactgtaa ccatagttga
    25921 tcgaatcgtt tgcagatact ggatccagat tttccaagcg gtaaaacgag tcggaatctt
    25981 tttttgtttc atttacaaga gctttcaagt caggataagg atcagtatat aaactgcggg
    26041 aagcataatt ccaatcatca agaatgccat ggatcatact gttcgtattg accagtgctt
    26101 cagcagacat gatcaataat aacaatatac tcagatgatt gaatgaaagt tttttatgct
    26161 gataaaatcc cacagcaaaa gcataaatcc ctaagaaaac cactgtcaat acaaaggaag
    26221 tcatcgtcac ataggtgtag cttccttcag gtttgatgcc ccatgccacc gcaaagagag
    26281 cagctacgac caaaatgatt cctaacaaca gcccacgatc gtcttgttct atcttttccc
    26341 atccttttcc tgcaagcagg agcactaaga aagagaacag ataggcataa cggaataaaa
    26401 acatattcgg tgcatgcata ccatgccaga acaaattcaa tggaacaaga taaaaacttg
    26461 cgataagtat ggcgaaaaga ctgccgtaca aaaatttatt tttcaacggt actttccgac
    26521 tggcaaaata aaacagacag aggactaatg gtagcagacc tgcgtaaacg aacggaatcg
    26581 atccgtattt tgtcgtgtca taaacaccaa tcatattttt catgattaga tccagataag
    26641 aagtcgcttc tgttttcaac gtagtgatct gactcagtgc ctcgccattt gaccgaagat
    26701 ccagcactgc tggcaataca atgatcattg aagcgccgcc tgccagtaaa gaagtgatac
    26761 cataaggaac aatcgttttt ttatattctg accagtttgt caatagacgg gcgataaaat
    26821 ataagaaaga aaatacgcca atcataaaac ccatataaaa actggataaa aacaagagta
    26881 aataactgat aaataaaagt ttcggccgtt taagatccat aacacgatga atccccaaaa
    26941 tcactaatgg aagataaaca aatgcatcca gccacatgat gatctccgaa tgtgcagtga
    27001 taaatgagat caatgcgtaa ctgacgctaa gtgcaacatg cccccagcga ggaatcttga
    27061 acgtacgtgc aagaaaccaa aaagccaatc cggcacagcc gaccttaagc aaagtcagaa
    27121 catacagtgc atctggcatc atctggtttg gaaaaaagaa caccagtggc gtgaagatcc
    27181 cgcctagata gtaagaaatt aaagataaat aattcaatcc tagagaagca ttccatgtat
    27241 aaaaaatact ttgctttcca agaagaacat ttcggaagct ggcatgaaaa ttagaaaact
    27301 gtgaaaaggc atcacttgcc aaaatacttc tgctgcttcc aggatagatt ccgatactta
    27361 gataaacaag tgctaaaatc aaaaacggaa tcaggaaact agctgctgcg tagcgtccgt
    27421 tttctctaaa gaatgacttt aaattttttt tcatatttat tttccaccaa atttctatga
    27481 agttgtattc agtttatcat atccttgttt ttctctgctt aaaaagagtc tagttttcac
    27541 aaaaaaataa aatttagaat aaataacttc ataatttgtt cgtataacaa aaataaacgc
    27601 aaaaaaaggg taggaatcaa aagtcccacc cttaaaaatt tttattaaat aaaaaaccgt
    27661 tcactatctg aacggtccaa gtatcattca attaaacgcg ttcaactttt cctgatttca
    27721 aagcacgagt tgacacccaa acttttttag gttttccgtc gaccataacg cgaacttttt
    27781 gtaagttagg tttaacagta cgttttgttg agttcatagc gtgtgaacgg ttgtttccac
    27841 tttttgtctt gcgacctgta aagtaacaaa cttttgccat ggtaatttcc tcctttgcct
    27901 tgatttggag caatagaata attcagctca taccagacta acatatcata tagaatggga
    27961 atttgcaagt acattttcat agatacaatt gacaattgag aagaataatt gtaaattaaa
    28021 caaggttata cctgaaattt tgcaaggttt ttgagtactt tgggtaactg ccttttattt
    28081 caagttgcgc tatgataaaa tatgatagaa gaaaaatggg agttttttac ccgttaagga
    28141 ggctcattca tggctgtaaa aattcaaacg tcagctggaa ccattgaaat taccaatgat
    28201 gtaattgcaa cagttgttgg tggcgccgcg acagatgtgt tcggtgttgt aggaatggcc
    28261 agcaaaaatc aaattaaaga taatattact gagattttgc gtaaagaaaa ttactcaaga
    28321 ggagtagttg tccgccaaga agataatggt attgctgtag atgtttatac gattatcagc
    28381 tatggtacga aaatctctga agtttcccgc aacgtccaag aaaaagtgaa atacaatcta
    28441 gaggcattat taggcgtaac tgccaattca gttaatgtct ttgtacaagg tgttcgtgta
    28501 ctgccagact aggcaggaga ctggctggta actcagcagt cgatctgaag gaggattatc
    28561 taggtgagtg taacagaaat aagtgcaagc cagttccagg aaatggtcca ggcaggtgcg
    28621 aatcgtctgc aagtaaatgc agaatacgtc aattcattaa atgtattccc tgtgccagat
    28681 ggcgatacgg gaacaaatat gaatctatct atgactagtg gagctaaggc agtagtagat
    28741 tcaacctcag aaaaagtagg agaattagca gcaatgcttt caaaaggatt gctgatgggt
    28801 gcgcgcggaa attccggcgt tattttgtct caattgtttc gtggattttc taagcaaatt
    28861 ccagatgttg tctcattaaa tgcttctgat cttgctgcag ccttcactca tggagttgaa
    28921 actgcgtata aagcagtaat gaaaccagta gaaggaacga ttttgacagt agctagagaa
    28981 gcagcgaaag ctggagaaaa gaaagcaaaa agtactgatg atgtcgttga agtaatgaca
    29041 gctgttgtaa aaggagcaaa gcgtgcttta gctaaaactc cagacttgct tccagtccta
    29101 aaagaagtcg gtgtcgtaga cagtggaggg caaggactgc tgtttgttta tgagggcttt
    29161 ttaagtgcat tgaatggaga attccaagcg gatgaaacat atgaaccttc tccagcagaa
    29221 atggatgata tggtcaatgc agaacatcat cgcagtgtcc aaggtcaaat ggcgacagaa
    29281 gatatccatt ttggttactg tacagaaatc atggtaaaaa tcggagaagg acctacagtc
    29341 gatagtacat tcgattacga agaattccgt aactatttag atggtatagg agattcttta
    29401 cttgtggtca atgatgacga gatcatcaaa gtccacgtgc atacagaaaa cccaggagaa
    29461 gtcttgaatt atggacaaaa attcggttca ttagtcaaaa tcaaagtcga caacatgcgc
    29521 ttgcagcatg agacgatttt ggaacacgat gaagaagtga acgagtttgc gaaaaaagaa
    29581 ataccacgta tcccgtatgg tatcgtagcg atcgctgctg gtaaaggcgt ccaagagctg
    29641 tttgaaagtt taggcgctaa ttatgttatc agtggtggac aaacaatgaa tccaagtacg
    29701 gaagacattg ttaaagcgat tcaagaagta aacgcagata aagtgattgt cttgccaaac
    29761 aataagaaca tcttcatggc agctgatcaa gcagcagaag tagcagatat cccagtagca
    29821 gttgttcctt caagaacgat ttcccaagga ttgacagcta tgctttcatt caatgatcaa
    29881 gcttctttag aagaaaacaa agaaacgatg acagaaatgt tgtctagcgt tgtgagcggt
    29941 caagtcactc acgcgatcag agatacctca attgacggtg tagagatcaa agaaggagac
    30001 tttttgggca tgatcgatgg aaaaatcctg atctctaacc cagatatcac agcaacagcg
    30061 ttaagtacac tagaacaaat gatcaatgag gacacagaga tcgtaacgat cttggcaggt
    30121 gatgaaggaa cagttgaaca agcaaatgaa tttgctgaga aactaacaga aaaacatcct
    30181 gatttggaaa tcgagatcca ccaaggagat cagcctgtct atccttatct attttctgct
    30241 gaataatttc tgtgtcagaa tatctttcta acacagtatt cattcataaa aggccttcgg
    30301 ttagtgatca ggtatgatcg ctgaccaagt cctttttttg ttaaaggagg gaggaaaaat
    30361 ttatgcgttc tttagatgat ccaatcacta tgctggcagg agtcggagaa aaaagagcag
    30421 ctagtcttgc cagcttgggc atccaaacga ttgaagactt actgacttat tatccttttc
    30481 gctacgaaga tattcaggaa agaaatctaa acgagatcca ggatcaagaa aaggttactt
    30541 tgaaaggaat cgtagtctcg cctcctgtga tgaatcgatt tggttataaa aaaagccgat
    30601 tgcaatttcg tatgatgcaa gaacatgatg tgttcaacgt ttcttttttt aatcaacctt
    30661 atctaaaaga aaaagtcatt ttatcggagg aaatcgccgt atacggtaaa tgggatgcaa
    30721 agcgtaaagc cttgaacggg atgaagattt taggttctca aacaatggat gacttttcgc
    30781 cgatatatca cgtcaacaaa tcaattcgtc aaacgacatt agttgatcta atcaaaaaag
    30841 ggtttcaaga atacggcaca ttgattgaag aaaatctgcc aaacaacctt gtggagaaat
    30901 atcgactgct tgaccgagct tctgctgtaa gaagtatgca ttttccaaaa gaccacgaag
    30961 aaaaccatca agccaaacga cgtgtcgttt ttgaagagtt ctttttattt caaatgcgtc
    31021 ttcaaggatt gaaaaaagca gaaaaagcag aaacgaatgg tttggagatc ctttatgatg
    31081 tccaaaaatt gaaacaattt actcaaaagc taccttttga actgacaaat gcacaaaaac
    31141 gtgtaacgaa tgaaatctgt cgggatcttc gcagtccgca gcatatgcag cgacttttgc
    31201 agggagatgt aggtagcgga aaaacagtgg ttgccgcgat tgcgttatac gctaccgtta
    31261 cagcaggttt ccaaggtgcg ttgatggtgc ctacagaaat cttggcacaa caacatatgg
    31321 aaagcttgca acagctgttt gatcccaatg aagtaaccat cgcattgatt acggggtcaa
    31381 cgaaagcaaa agaacgacgt gagctccttg aaaaactaga gcaaggggaa attaacgtcg
    31441 tgatcggcac acatgcattg atccaagatg gagtcgaatt tcagaattta ggtctagtta
    31501 ttacggatga gcagcaccgt tttggcgtga accagcggaa agtacttcgt gaaaaaggct
    31561 ggcgaccaga tgtcttattt atgacagcga ctccgattcc tagaacatta gctattacag
    31621 catatggtga gatggatgta tctatcattg atgaacttcc agctggacgt atcccgatcg
    31681 aaacacgctg ggtaagaaca cctcaattgg acagtgtact ggattggacg aaaaaagaac
    31741 tggcaagagg acatcaaatg tatgtcatct gtccgctgat tgaagaatca gaagcattag
    31801 atgtaaaaaa tgcagtggaa atctatgaaa aacttcgtga actatttgca ccaaaatatg
    31861 aagttggctt gttacatggt aaaatgaaga atcaggaaaa agaagtaatc atggaagcct
    31921 tcaaagacaa ccagatgcag atattagttt cgactactgt aattgaagta ggggtaaacg
    31981 tgccgaacgc gaccgtcatg ctgatcatgg atgcggatcg atttggattg gcacagctgc
    32041 accaacttcg tggacgtgtt ggacgcggaa gtgatgcttc ctactgtatc ttagttgcta
    32101 atcctaaaaa tgaactaggt gtggaacgga tgaaaatcat gacagagacc accaatggtt
    32161 ttgtactaag cgaaaaagat ctggaattac gtggtcctgg tgaagtattt ggcttccgtc
    32221 aatctggtct gcctcaattt gcgattgctg acttggtgac ggatggaaat gttttggagg
    32281 tagccagaga agaggctgca gccctttggc aaataaagga ttggcagatg cttcctgagt
    32341 atcagccttt agcgcaaagc ctccaaatag aaaatcagga taatcgttat ttcgattagc
    32401 agactgtgct atactttata ctgatgacgg aaaaaggagt ggaaacaatg aaaattgccg
    32461 tagatgcaat gggcggagat cacgcacctc aagcaattgt agaaggcgtg gctttagcgc
    32521 agcaagattt tccagaagta gaattcttac tttacggaaa agaagcagaa atcaagaaat
    32581 acttaacaaa tgaaaaaaac atcacgatta tccatacaga cgaaaaaatc aatagtgatg
    32641 atgagccagt aaaagcaatt cgacgaaaaa agactgcatc aatggtcctt gctgcacaag
    32701 cagtgaaaaa cggtgaagca gatgctgtat tttcagcagg gaatacaggc gcgctactag
    32761 cagcagggtt gttcatcgta ggacgtatca aaaatatcga acgccctggc ttgatgtcta
    32821 ccttgccagt agtagggaaa gaaggtgccg gtttcgatat gctggatctt ggcgctaacg
    32881 cagaaaacaa accagaacat ttgttgcaat acggtatttt aggttctttt tatgcacgta
    32941 aagtccgagg tatcggacgt cctcgtgtcg cactcttaaa caacggaaca gaagcaacaa
    33001 aaggtagtga agtgacgaaa aaagcctatg aactccttca gaatgaaaca agcttgaatt
    33061 ttattggaaa cgtagaagct cgtgagctac tcaatggtgt ggctgatgta gtggtcacag
    33121 atggatttac aggcaacgct gttttgaaat ctattgaagg aacagcaatg aatatgatga
    33181 atctattaaa atctgctatt ctaaatgaag ggatcaaagg aaaaatgggc gctatgcttt
    33241 taaaagacgg cttacgttct ttgaaagcag aaatggatta ttccaaacat ggcggtgccg
    33301 ttttgtttgg cttgaaagca ccagtcatta aaactcatgg agcaacaggc cccgatgctg
    33361 ttcgctatac gatccgccaa atccacacaa tgcttgagac agatgtagtt ggacaattag
    33421 tcgaacaatt tgaaaaaagc gaagaatagt atttggatat ctgaagcgat ccgttccatt
    33481 gaaaaaaagg tggacattcc tgaaaaatgc cagtaaaatt agccatggtg taggtaattg
    33541 acaagtgtat gattcttgga ggtgaaaaag ttgactcgcg aagaagtatt taacaaagta
    33601 gcgaaaatta tttcaaatca ttttgagata gataccgata aagtgacgga tgaattgaac
    33661 atcaaagatg atttaaaagc tgattcaatt agtattatgg aattcgtttt agagcttgaa
    33721 gatgaattcg gtacggaaat ttcagatgaa gacgctgaac aaattgaaac agtcggtggc
    33781 gcagtagatt atatcagcag ccatcttaaa taatttcaaa taaaagcaaa gaaggataaa
    33841 aagctgcatg cagcttttta tccttctttt tttaatcttt ttgacacgta aaagtcattt
    33901 ttctgataat tctggcgata aacagaaatt atgttgcaaa gtaaagcggt tttctatata
    33961 attattaata attcattaca caaagataag aataaccttt gttataaaac gatttattct
    34021 gtgtaatgtc cttttttatt aagaaaaact tccatttagg aagcagagag gggtattcga
    34081 ttgtccgata accaattatt agaagttcag aacctacata caggattccg actcaaagat
    34141 gactattacg atgcagtaga tgacgtttca tttactttag acaaaaacga gattttagca
    34201 atcgttgggg aatctgggtg cgggaaaagt accttggcta ctacgattat gggattactt
    34261 gatcctaata acacaaaaat tacaggtgag attttatata acgatctgaa tttaatcgac
    34321 ctgaacgaaa cgctctataa taaaatccgc ggaaatgata tcggaatgat tttccaagat
    34381 ccgttgtctg cattaaatcc tctcatgaga atcgaagacc agatcaaaga aggactttcc
    34441 tatcacacaa agatgaatgc agaacagcgt caagctcgtg cactagaatt gctagaacaa
    34501 gtagggattc ctaatcctgc gagagttgga cgccaatatc cccatgaact atcaggcggt
    34561 atgagacaac gtgtcatcat cgcaatcgca atcgcctgca aacctccaat cgtcattgca
    34621 gatgaaccga cgacagccct agatgtaacc atccaagcac agattcttga tttactgaaa
    34681 gaccttcagg aagaaacaaa aacagggatc atcttgatca ctcatgactt aggagtcgta
    34741 gcagaaatgg ctgatcgagt ggcagtgatg tatggcggac agttcgttga agtagcaggt
    34801 gtaaaagaac tgtttgatca tcctaagcat ccttatacac gctctttact gaactctata
    34861 ccacaagaag gaaatcatga tgcagaactc catgtgatcg aaggtgtcgt tccttctctg
    34921 aaaaacatgc ctcgtaaagg ttgtcggttt gcaccacgta ttccatggat accagcaagc
    34981 gatcatgaag aagagcctat ccttcatgaa gtcgcaccga accacttggt acgttgctcc
    35041 tgctataagc atttccactt tagagacgaa aaaggagagg tgtagatgac agaattaatc
    35101 acaatcaaag acctgaaagt tcattaccct attcgcagtg gattcttcaa tcgagtaacg
    35161 gatcatgtat atgctgtaga tggtgtggat tttattatcg aaaaaggaaa gacatatggt
    35221 ttagtgggag agtctggctc tggaaaatct actacgggaa aagccgttgt gggattagaa
    35281 aaggtaacag ccggacaaat catgtatgaa ggaaaagatg taacgaagcg aagcaaccgc
    35341 aaaaaaatgg gttataacaa ggatgtgcag atgatcttcc aagattcaat gtccagtttg
    35401 aatcctaaaa agcgagtgtt ggatatcatt gctgaaccca tccgaaattt tgaacggtta
    35461 agcgatcaag aagaaaagaa aaaggtaaaa ggactgctag atatcgttgg gatgccggaa
    35521 gatgcgctat ataaatatcc tcatgaattt tcaggcggac aacgtcaacg tctaggagta
    35581 gcccgtgctg ttgctaccaa tccaaaactg atcgtagccg atgaacctgt atctgctctg
    35641 gatctatctg ttcaagcgca agtattgaat ttcatgaaac gaatccagca agaatacggc
    35701 ctcagctatt tattcatttc acatgattta ggtgtagtaa aacacatgtg cgacaatatc
    35761 gcaattatgt acaaaggtcg atttgtagaa atcggtacaa gagaagacat ttataatgac
    35821 ccgcgacata tctatacgaa acgtctgctt tcagctattc cgcaaatcga tgtagaaaat
    35881 agggaaagcc acaaagaaaa tcgacgaaga gtagaacaag agtatatcca aaaccaaaaa
    35941 gaatactatg atgcgactgg tcgagtctac gatttgcgta cgatcacaac tacacacaaa
    36001 gtggcgttga aagatggagg tgcaagctaa tgtggaaaac gattctgcga cgtgttttat
    36061 tgatgatccc gcaagttatt attttaagtg ttctgatctt cttattagcc caagcgatgc
    36121 cgggggatcc atttaccggt ttgatcaatc caaatcagga tccggcagtg atcgaacaga
    36181 tgcgacaagc agctggcttg aatgacccat ggtatgtcca gtacttccgt tggatcggaa
    36241 atgctttgca aggcgatttt ggtcaaagtt tcttatacaa acgctctgtt gctgacttga
    36301 tcggcgaacg gatcatcaac actttatatc tatcgatctt gacagttgtc cttacttatt
    36361 tgattgctgt gcctctgggg atgcttgctg gccggtatca aaattcaatc ttggataaga
    36421 ttgtcgtaat ctacaacttc tttagttttg ctgttccttt atttatcttc ggcttgatca
    36481 tgctatttgt ttttggttat cgtttaggct ggttcccaac aagtggatca caaacactag
    36541 gtttgcaagg tggatttatc actcaatgga tagaccgttt gaaatatatt ctgttaccat
    36601 caattaccca agcatttttg gcgactgccg tcacaatcca atatctgcga agtgaagtaa
    36661 tcgattcgaa atcgctcgat tttgtcagaa cagcccgttc caaaggggta ccgacgaata
    36721 aagtattcag tcgacatatt ttccgaaatg cagcgttgcc gatggcttct caaatggggt
    36781 atgaaatcac ttcgttgatt gctggttctg tagttatcga aaagattttt ggttatccgg
    36841 gagtcggaaa actatttatt gattccatcg gccaacggga ctataccgtg atcacatcct
    36901 tagtattgat tttaggaatc gcgacgctag tggggacatt actttcagat atcatcatga
    36961 gtatcgttga cccgcgtatt cggattcaat aaaaccaatc agaaaggaga atggatcgat
    37021 gagtgaaaaa aacaatacag cagttcaaga aagtattcct cctatgggga tacgaatgat
    37081 tgctcgagaa tttaaaaaag ataaaattgc tattttttca ttaggtttgc tagtggtttt
    37141 attattagtg atctttatcg gtgcgatgct gaccgatcaa gacaaagtga tgtatgttag
    37201 tatcttcgac aaatacgctg caccaggaac agtttcgaca caaggacaaa agttcattct
    37261 gggagcagat gaaggcggac gtgatgtatt aggacaattg atcataggtg ctagaaactc
    37321 tgttacgatc ggatttgcga tcacgatcct tacttcgatc atcggggttg gattagggat
    37381 catctctggc tactacggag ggatcattga caacatcttg atgcggatcg ttgattttat
    37441 catgattcta ccgatcatgc tgatcattat cgtcttcgta tcgattattt ccagatacaa
    37501 tgtctggtcc tttatattca tcatgagtgc attttattgg gtagctaaag cccgattatt
    37561 ccgaagcaag acattatctg aagcaagaag agattatgtc agtgcctcaa aaacaatggg
    37621 aaccaatgat tttaaaatca tgttccgcga aatcatgccg aatctaagtt cattaatcat
    37681 tactaatttg acgatgaact ttgcggcaaa catcggtatc gagacaactt tgactttctt
    37741 aggtttcggc ttgccggcaa atgtacctag tttaggtaca ttgatcggtt atgcaagtaa
    37801 cggagaagtc ttagtgaatc ggcaatggat ctggttaccc gcatcaatcc ttattttagt
    37861 tttgatgttg agtatcaatt atgttggaca agcattcaag cgttctgcag atgcgcgcca
    37921 acggttaggc tagtatagaa gcgaaggggg aaataggaat gaagaaaacg atttttggat
    37981 ttgcagcgct gatgtctgct gtcgttcttg cagcatgcgg gggcggaggt acagatacct
    38041 ctggaaacaa ctctggaggc aacggcaata acaaagagga attaactttt ccaattgcaa
    38101 caaaaaataa tgatgatgca atcgaagacg gcgaattaga agctgcggtc gcaacggaca
    38161 gtcagtttaa aggattgttc cagtgggagt tttaccaaga ttcatatgat gcagctttta
    38221 tggctccttc tcatgaaccg ctatttgcaa acgatgacga tttcagaatc acagacgacg
    38281 gagctgcaac gcttgatcta gatgaagata cgaaaaaagc gacaatcaaa gtaaaagaca
    38341 acgtcaaatg gtcagatggt gaagatgtaa cggcggacga tgtgattttc ccttacgaaa
    38401 tcattgggaa taaagattac actggtatcc gttatgacga cactttccgt aacatcgtag
    38461 gtatggaaga atatcatgat ggaagtgccg acacaatctc cggaatcaaa aaaatagacg
    38521 acaaaacagt tgaaatcgaa tataaagaag taaacccaag catgcttcaa tcgggtggtg
    38581 gtatctggtc atatgcagca ccaaaacata cgttagaagg tgtagcaatc aaagatatgg
    38641 aatcaagcga tcaagtacgt aaaaatccag tgacttttgg cccttattac atgagtaata
    38701 tcgttgcagg agaatcagta gaatacttgc caaacgagca ctactggaat ggtacgccta
    38761 aattgaaaaa gatcacgatg aaatctgtac cgatggcaag tgcaactgaa gcattgaact
    38821 ctaaattata tgatatgatt ttccaaatgc caacagatac ttacgatacc tataaagaaa
    38881 ttgctggcta tacaaactta ggccgtgaac aaacttctta tacttatcta ggattcaagt
    38941 taggtaaatg gaatgcagat acaaagagtg tggaatacaa tccagattca aaaatggctg
    39001 ataaatcatt acgtcaagca atgggctatg cattagataa taatgcagta ggtgaacgtt
    39061 tctatgcagg tttgagaagc aatgcgactt cattgattcc tccagtattc cagtcatacc
    39121 atgatgatga gatgaaagga ttcacacaag atctagacaa agcgaaaaaa ctattagatg
    39181 atgctggcta caaagatgtg gatgacgatg gtttaagaga agacaaagat ggaaataaac
    39241 taacaatcaa ctttgcttcg atgtccggtg gggaaacagc gcaaccattg gcagattact
    39301 atatccaaca atggaaagaa attggtttgg atgtccaata cacaacaggt cgtctgatcg
    39361 aattcaattc tttctatgat aaattagaaa acgatgatcc tgaaattgat gtttaccaag
    39421 ctgcttggaa tacaggaact gatccaaatc caagtggact atggggacca aatgctgcgt
    39481 tcaactacac tcgttatgaa tcagaagaaa atacaaaatt gatcaacgat atcagttcaa
    39541 gcaaagcatt tgatgaagag taccaaaaag aagcatatca aaaatggcaa caatatgcat
    39601 ttgaagaagc atttgcgatt ccaacgttgt tccgtaatga agtattgcca gtcaacgacc
    39661 gtgtcaaaga ctgggattgg tcttatgatg taccaaaccc atgggcaaat gtttctgtta
    39721 cagcagattc acgttcataa tcactaaaaa tgaccgaaaa agggcgatgt cctttttcgg
    39781 ttttttgata tttttctgtt tatttctcta atattcaggt caaggcgctg atttcatgac
    39841 ttctccaata aacggtgttc aaagtccagt ttctcggtat taagtcaaat ttatgcaaaa
    39901 atatggaaag ccattttcac aaaatttttt cttcatactc gaaactaaac gaatttttca
    39961 caacttctcg tcaatcacta ggattattaa agctttactt accttttgac cgaaccattt
    40021 caaatttgac aaaaaaccag tataataagg aagtatcgaa aaaatatcca taaaaggaat
    40081 gtggaaaatg gacaaccagc tgacaaaaga actaaaagaa aactataaca tcgtttttca
    40141 cgatctaaat ttgcttgaac aagcttttac ccattcatcc tatgtgaatg agcatcgcaa
    40201 tctgcaatta tcggataatg agcgacttga atttttagga gatgccgttt tagaactgat
    40261 ggtttctcag tatttattcc gtttatatcc tcatttgcca gaaggaaaat tgacaaaaac
    40321 acgagctgcg atcgttcgcg aagacagctt gtcgaaattt gccaaagaat gtcactttga
    40381 tcaatatgtt ttgttgggca agggagaaga gaattcagga ggacgtacgc gaccagcatt
    40441 gctttgcgac ctattcgaag cttttttagg cgcgttatat cttgaccagg gattcgacac
    40501 gacccatgca ttcatcgaaa aagtgatttt tcctaaagtc aaagcaggtg ctttttcaca
    40561 tgagatggat cataaaacaa aactacaaga agtcttgcaa aaatcaggtg atgtatcaat
    40621 cgaataccga ttgatcaatg aagaaggtcc agctcatgaa cgagtatttt ggatcgaagt
    40681 ttatgtagat gatcaattga ttggcactgg acaagggaaa tcgaaaaaat tagcagaaca
    40741 agctgcggcg gaaaatgcat tggcagcact gtaaaagtaa gtgagggaaa gctttgtatt
    40801 tgaaacgaat tgaaatagcc ggttttaaat catttgcaga caagacagtc attgattttg
    40861 aaaatagcgt cacagcagtg gttggaccaa atggcagcgg aaaaagcaat attacagagg
    40921 ctatccgctg ggtattagga gaacaatctg ctaaaagtct gcgaggcgga aaaatgccgg
    40981 atatcatctt tgccggttcc gatacccgta agcagctgaa tattgcagaa gtcacagtga
    41041 ttttagacaa tagtgatcat tatctgccat tggagtacaa tgagatcagt gtaacccgcc
    41101 gttatcgacg gactggggaa agcgagtttt tcatcaataa acaaagctgc agattaaaag
    41161 atatccaaga attgttctta gattctggat taggaaaaga atcgttctca atcatttctc
    41221 aaggaaaagt agaagcgatt ttcagtagta aaccggaaga ccgtcgtggg atctttgaag
    41281 aagcagctgg tgtcttgaaa tacaagcagc ggaaaaagaa agcagaacag aagctttttg
    41341 aaacagaaga caacctcagc cgcgtccaag acatcatcca cgaattggaa gaacagttaa
    41401 ctcctttggc cgcccagagt gaggcagcaa aggagttttt acggctaaaa gaaacactga
    41461 ctcaaaccga tgtctctttg atggttgctg aaatcaagac agcaaaaaaa gattgggaca
    41521 acaaacaagc acagcttgcg aaattcaatc tagaattagg caaactatct gagtcgatcc
    41581 aagaacaaga atccattttg gcgaagcagc gtaaagaaaa tgcgcaagcc gatcgtctga
    41641 tcgaaaaaaa tcagcaagta ttattagatc tttcggaaaa actgaagcag acagaaggac
    41701 aaaaagatgt tttgcaggag cggacaaagc atacacaaaa aagctcgcaa gaatatcaaa
    41761 cttcattagc agaagcacaa aaaaaggtta aacattttga aaagcttcaa gaaagcttga
    41821 tgaaagcagc agcagaaaaa gaaacagaga tccaaaaagc tgaagcaaat ctcataaaaa
    41881 cacagcaaga attagaaaaa taccaaaaat caacgaaaga attattggca gaattaagag
    41941 atcaatatgt tgatttgatg caagaacaag cagctgtagg aaacgaactg aagtatctag
    42001 aacgtcaata tatacaagaa acagcaaaaa gcaagcagac gttagccaag caatcggaag
    42061 tagaagcatc agtagaccga ttgatcttac aaaaagaaga attgacacaa aagcaggcgc
    42121 agctaaaatc atctttaact gaaacaaaag agaagttaga aatgatccaa caaaacggga
    42181 aaaagttcca agaagcatta gcaaaagaac agcctaaaat gtatcaatta atgaatcaag
    42241 tccagcagct acgtgctcgt aagaaaagcc ttcaagaaat ccaagaaaac tattttggtt
    42301 tttaccaagg ggttcgattg gtcttgcagc ataaacagca gctttcgggt attgtcggag
    42361 cagtggctga actgatcgat gttcctgcag atttcacgtt agctatcgaa acagctttag
    42421 gtggggcagc ccagcatgtc atcgttgaaa atgaaaaaga tgctcggcaa gccatcacgt
    42481 atttgaaaca gcaaagagga ggaagagcaa cattccttcc actgacgaca atcaaaccaa
    42541 gacaattacc ggctcatata ttgacacaag cagcagctgt agaagggttt atagggattg
    42601 ccagtgaaca agtcagttat cccgatcaaa tccaaactgt ggttcaaaac ctgctaggaa
    42661 cgatcctttt agccaaagac ttaactagtg ccaatgcaat cgcgcaaacg atccgctatc
    42721 aatatcgagt ggtttcctta gaaggtgatg tgatgaatgc cggaggatcc atgacaggtg
    42781 gagcgaataa acgaggaaac caaggcagtt tgtttgtaca aaatcaagaa ttgaaacagt
    42841 tgactagtga atttgaagaa gcagataaac aactccaagc acaagaaaaa aaagttcagg
    42901 agctgcaaca agaaacagct cgtttagccg aagaacaaga agttttgcgt acacgaggcg
    42961 aacaattacg ttttgaagaa caagaagcga caaatcagct acaaaacatc ataaatgaac
    43021 ttgaacgttt tgaaaaagaa aagcaaatct caacttttga gacacgtgaa ctgcagcagt
    43081 ttatcgaaga ttacgaaaag caaacgaacg aattgaaaga caaacaaaca gatcttgaat
    43141 cgcaacgaca aaaaatcgac gaagaaatca aatcgttaag tcaagaaagc gaccagatgg
    43201 aagccagaag agcacaagta caaagtcaaa aagcacaaga acaagcagat cttgctgtct
    43261 tgaaagagca gtttaatcat ctgcagatcc agctccgcgg tgcccgagtc caaaaagcag
    43321 aggcaaccga acgtcaagaa gcgatagaaa agcagttggc gacattgaca gcagactttt
    43381 ctgatcatga agtcacagaa gaaagtttgg aaaaacaaat taacgaatta tctgctcagc
    43441 gagaaacatt aaaagccgag ttggcaaaag ccaaagagca gcgagataga aggcaaaagg
    43501 agatcgataa gcttgaagca gtcttggcag agcgtaatcg tgagcaaaaa gcacgactgt
    43561 cggaacaatc caaattagaa gtccaaaaag accgagctga aatgatttta gataatcatt
    43621 tgacctatct gcagtcagaa tatcagctga catttgagaa agcttcccaa gactatcaag
    43681 aaacaaccga tatcgaagac agtagaacaa aggtttcatc cttaaaagaa cagattgaaa
    43741 aactgggacc agtaaactta aattcaatcg aacaatacga acaagtcagt gaaagacata
    43801 cattcttagc aacacagcga gatgatctgt tagcagcgaa aaaccaattg tttgaaacga
    43861 tggatgagat ggatgatgaa gtgcggacaa gattcaaaga agtatttgaa gctatccgtc
    43921 aagaattcaa aattgtcttt ccaaatatgt ttggcggcgg taaagctgaa ttagtactga
    43981 cggaaccaac tgatttgctg aaaacaggta ttgagattga agtacaacct cctggcaaaa
    44041 aactgcaaag tctaagtttg ctttctggag gagaacgagc acttacagcc atcgcgttgc
    44101 tcttttccat tatccgtgtc tgtcctgttc cgttttgtat cttagatgag gtagaagcag
    44161 cgttagatga agccaacgtg aaacgttttg gtcgttactt gagcgatttc caagatgaca
    44221 cacaatttat cgtagtcaca caccgcaaag gaacgatggt cgcagcagat gtactgtacg
    44281 gagtgacgat gcaggaatcc ggtgtatcaa aaatcgtttc tgtacggatg gaagatatca
    44341 atgaagaggc gaaaatcaac gaaacgaaag tgtaggaacg aaaatgatca aattagtagc
    44401 aatcgatttg gacggtacat tattaaatga acaaaagctg atttcagatg agaataaaca
    44461 agcattagca caagcaaaac agcaaggggt caagatcgtt ctatgtacag gacgcccctt
    44521 agctgcgatg gcgcattatc tgcaagaatt aggactggta gatgaaggtg actacagcat
    44581 cactttcaac ggcggtttgg tacaaaaaaa tgatactggt gaaatcatgg aaaagaaagt
    44641 gatggaagta tcagatatcc aacgcttata caaactggct cagcaattgg atctgccact
    44701 agatgttttg tctgacaatg tggttttaca gctgcctagt gccccaagga agcaatcctt
    44761 gtacaatgtg ttgaataagc tgctgcaatt ccaaccagcg gatataagcg atattacaga
    44821 tgaatttgtg cttaataagg cagtaatcgc ttatgaccaa gaagaattag atcctaaaat
    44881 caaagaaata ccagcagaat tccatgaaat gtatgagatc atcaaaacaa gaagtatgct
    44941 tttggaattt atgccaaaag gtgttacaaa agcttatggt atttctttat tggcaaaaga
    45001 tcttggtttg aaacaagaag aaatcatggc gatcggtgat gaggaaaatg atttaccgat
    45061 gatccaatat gctggactag gcgtagcgat ggagaatgct gtgcctttcg tcaaagaagc
    45121 agcagatttc gtgacagcca gcaatgaaga aaatggcgta gccaaagtga tccaaaaatt
    45181 tgtattagag tagggggagt caaatgggat tttttgataa aatcaagcgt gcttttactg
    45241 gcgaagagaa aacagaagaa gttgaagtac aggagaagta cgacaagggt ttagaaaaga
    45301 cgcgtaaaac atttggtgaa cggatgaatg agttgtttgc caattttcga acagtcgatg
    45361 aagacttttt tgaagaatta gaagaaacac ttatcggtgc agatgtaggt tttgaaacag
    45421 cgatacgaat taccgaagca ttacgtcaag aagtgaaact cagaaatgcg aaaaaatcgg
    45481 cagaagtcca aaatgcgatc atcgagaaac ttgtggatct ctatgaagcg gaaggaatca
    45541 atgaagtaaa tgaactaaat atccaagaag acggactaac agttattttg tttgtcggtg
    45601 ttaatggtgt agggaaaaca acaagtattg gtaaacttgc ccatcagttc aaaaacgaag
    45661 gtaaaaaagt attgatggca gcagcagata ccttccgcgc tggagcaatc gaccagttag
    45721 ttgtctgggg cgaacgcgct ggtgttgaag ttgttcgtgg caatgcagga ggcgatccag
    45781 cagctgtcgt attcgatgct ttggaaagag caaagacaga gcaggcagat gttttactag
    45841 ttgatactgc aggccgactg caaaataaag tgaacttgat gaacgaatta gaaaaaataa
    45901 aacgagtaat ccagcgggaa ttaccagaag caccccaaga aacacttctt gtattagatg
    45961 caaccactgg tcaaaacgcg atggttcaag caaaacaatt caaagaaaca acagatgtga
    46021 ccggtcttgt tttgacaaaa ttagatggta cagcaaaggg cggtatcgta cttgctatcc
    46081 gtaatgaatt gcatttacca gtgaaattgg tcggtcttgg tgaaggaatc gatgacttgg
    46141 agccgtttga tccaaatgat tttgtcgttg gattgttcaa aggattacta aaagaagaat
    46201 aacccatgtc taaaaagcag gagctgtgac aaaagttgca gctccttgtt tgaatgattg
    46261 tttttaacat agctgtgttt ttgatgcctt catttttata cttatttgta agcggttctc
    46321 aaacaatttc gttctttttc ttagactttt tgattataat tagattcata tgaattggag
    46381 gtcacttaat gatgaatttt aagcaattat tattgcatgt caatgcgcgc ccttttatcg
    46441 accaagctcg atttggtata gaacgggaag gacagcgggt tgatcttgca ggaaatctag
    46501 caaaaaccga tcatccagca atctttggcg atcgatccta tcacccctat atccaaacag
    46561 attttagcga aacacaaaca gagatgatca cccctgttac cgattctatt cccgaattat
    46621 ttcagtatct cgctgctgtt tatgatgtga ctgctcgttc tataccgaaa gaagagatga
    46681 tctggccatt aagtatgcca cctgccttac cggaaaaaga cgaagagatc attattgcaa
    46741 aattaaaaaa tttcgaagat gtcttgtatc gacgttattt agcaaaagaa tacgggaagc
    46801 gaaaacagat ggtaagcggt attcatttca attttgaatt tggcgatgag ttgctaagaa
    46861 cattgttcag ccatcaggaa gaatttcaag atttttccga attcaaaaca gaactttatt
    46921 tgaaaacagc gagaaacttt atgcgctatc gctggatgat cacttattta ttcggtgctt
    46981 caccaatgag tgagaagaac tactttttag atgaatcaca tccgcaagaa cctgttcgca
    47041 gtattcgcaa cagtgcgctg ggctatacga atcatccaaa tgtgaaagtt tcctatgctt
    47101 ctatgaaaca gtatttagca gatatcgagc gaatgatcga agaagggaaa ctttcggagg
    47161 agaaagaatt ttatacaccg cttcgtttcc gaggcggaaa gaaagtcgca gatttagcaa
    47221 caacaggtgt tcgttatatt gaattgcgga atatcgattt gaatccttat gcaagattgg
    47281 gtatcaatcc agagcaagtt cggttcttac aattattcct gatgtacatg ttatggacag
    47341 aagaaaaaga agactgtgac caatgggtag cagaaggtac gactcgaaat aacaaagtag
    47401 cactagaaca accatcagat caaacagaat ttcatcaaga aggtagagaa attcttgaag
    47461 gaatgaagca aatgctggtt gaattggatt ggttggattc tctttattta gtagaggaag
    47521 cattgactca aatggatcat cctgaacaaa cgttagcagc gaaactctat caagaagcac
    47581 agctatcgag tcagcaagaa gttgctgtgg cattgggaca tcaatattat aaagaaagcc
    47641 atgaacgtcc ctatcagttg gccggttttc gcgaaatgga actttctact cagatattta
    47701 tgttcgatgc catccaaaaa ggtgtccaag tcaaagtatt agatgagtcg gatcaatttt
    47761 tgcgtctgca attccaagac catgtagaat atgtgaaaaa tgcaaacatg acaagtaagg
    47821 acagctatat cgtcccactt atcatggaaa acaaaacagt aacgaaaaaa gtcttaaaag
    47881 aagctgggtt ccgggtacca ggaggcgcag aattttcatc catggaagaa gcggtaaaag
    47941 cttatccgag atttgccgag caggcatttg tgatcaaacc taaatcaacc aattacgggt
    48001 taggtatcac gattttcaag gaaggagcta gtctggaaga ttatcaagca ggtttagcca
    48061 ttgcttttcg tgaagacagt tcggttttag tagaagaatt tatgccggga acggaatatc
    48121 gtttctttgt gatcgacgga gaagtccaag ccatcatgtt gcgagtccct gctaatgtta
    48181 ttggtgacag tatccgaaca gtgaaagaac ttgttgaaga aaaaaatagt gaccctttgc
    48241 gtggaacgaa tcatcgtgca cctttagaat tgatccaatt aggtgaatta gaacaattga
    48301 tgttgaaaga acaagggttg acgatcgaat cagttcccca agccaatcaa attgtttatc
    48361 taagggagaa ctcaaatatc agtacaggtg gtgattcgat cgatatgact gatgaatttt
    48421 ctgaagctta caaaaaaatc gccgtttctg cggtagaagc actaggagct aagattagtg
    48481 gtatcgattt gattatacca gataaagaaa tcgatcctac aactgataaa aaagcatatg
    48541 ggatcatcga agcaaatttc aatccagcca tgcatatgca tgtttatcct tttgcaggaa
    48601 aaggcagaag attgacgatg aatgtattga aattgttata tcctgaagta ttttaaaaga
    48661 aaaagctttt gacagattgt cctatttgat gtcaatctga tcaaaagctt tttttgcatg
    48721 taaaaattta tgtgtttttt cgttttaaaa taaacgatcc cagaagcttt ttttcttttt
    48781 tggtttttct ttttcagctg gcgaagagtt ttcttctggg tatttttttt cgatatcaat
    48841 cacaggttca tttactgctt cttttgctgt taagagcaat ccgaattcct caggatttgc
    48901 agtgacgtaa tcgttgacta cagtgaaacg gctattgctt ttcgttgcta gctggatata
    48961 ttggttttgg acagaaaggg gtagagcccc attcaagagt atggaagcat ctggatgttt
    49021 tttgagttct tttaaaaagt tttctttgtt ttttggttgg atcatttcag caacagtcat
    49081 actaagatag cagcgttccc tgaatgtccc taaatattta tgctgttctt cagggttcac
    49141 taaaggtgta ccataaagtc ccttatccaa atggcttttt acatcatctt gtgccataaa
    49201 aaataccctc cttcttctct ttgtctttct tacgattata gcatattccc aataatacct
    49261 aaaacatatg aaaaagcggt tgcttttgtt caacgattca cttaaaataa gaatgaaaat
    49321 cattctcaat tagaaaggtg gattggatgc gctacggacg actagtagca ttattagtta
    49381 ttttaagtag tatttcattg ttcatcggag tatcgaatgt acaattgtca gaactgctcc
    49441 agttagatgg gcaaagctta caaatcttgc tagtgactcg tttgccacga acgatttgtt
    49501 tgatccttgt gggagcgacc agtagtattt gtgggttgat catgcaacat ttgacccaaa
    49561 ataaatttgt ttcaccaacg actgcgggca cgatggatag tgcgcgttta ggtattttag
    49621 tggctatgat tttcctacct ggtgcatcct tgattgtccg atccttgaca gcattttgct
    49681 ttgcttttgc aggaacattg ctttttttat cccttacgcg attgttcctc cagaaaaatc
    49741 aattgatgct tccgttgatt ggagtcatgt tagggaatat cattggttca gttgctactt
    49801 tttttgctta tcaattccag ttggtacaaa atatgacttc atggcttcaa gggaattttg
    49861 cgactgtgat acgaggaaat tatgagttat tgtatgctgt tgttccattg ttgctcttgg
    49921 tttggctatt tgcttaccga tttacgatca ttggtctggg cgaatcgttt gcagtaaatc
    49981 tgggaataga ttaccagaag atgcagtttt taggcattgg cttagtatca ttggctagtg
    50041 cagtcatgtt gatcatggta ggaagcattc cttttatcgg aatgatcatt ccgaatcttg
    50101 tctctagaat atatggagat caagtgcaca aaacaattgg cgtaactgct ttagcaggta
    50161 gtttgttctt agtattttgc gatcttgtcg ctcgcgtgtt gatttttcct tatgaaatac
    50221 cagtcagtgt gatcgttgga atcatcggtg gggctatctt cctttatctt ctgataaggg
    50281 gacgacgata tgcttaaaaa aaagccatct atttttattg gtatgcttgt tcttgtttta
    50341 tttgttacag gaatgtactt gacgatccat acatatggaa actggcattt tgcatgtgca
    50401 ttgaggagta agaaaatttt tgcatttatc cttgtctcgc tagctgtcag cagtgccaca
    50461 atcagctttc agacaattac gcataaccag tttttgactc cttcagtatt gggacttgag
    50521 tcgttatatg tccttgtcca aacggtcctt ttcttcttta tcggaggagt gacgatgctt
    50581 cagcagacag gtacagtttt tttcttattg aacgttgggc tgatggtcgg gctgagtcta
    50641 ttgttatttt tctttctttt gaaaaaaatg agagcgaatc tttttttatt actgatgtca
    50701 gggatgattt taggtacgct ttttggtagt gtcagtacct ttttacaagt catcatggat
    50761 ccgaatgaat atgatttgct tcaaggcaga ttatttgcaa gctttggcaa tatccagagt
    50821 cagtatcttt tgcctgcttc tttgatcatt atcggctgct ggtacctgtt atttcgatat
    50881 cgacatgtgc tagacgtttt ccatctcgga aatgaacaag cagtaaacct cgggatagac
    50941 acagatcgtt ttgaattttt gattttatgt tgtgtcagtc ttttgacagg gacatcaacg
    51001 gctcttgtgg gtccagttac ttttttaggg tttattgtcg caaatatcag ttatcgtgtc
    51061 ttttctactt atcgtcatgg tcagctattt atcggaagct ttctggtagc tatgctgttt
    51121 ctgacaggag gacagctcgc agtagagcag attttcggct ggaatacaac agtgagtgtc
    51181 gtcgttgaat ttgtcggagg aatttatttt gtcacaaaat tgattcgcga aaggaagagt
    51241 atcctatgat tgatttacaa aaggtcaata aactgtacca tggaaaatca gtggttaaag
    51301 atgtacagtt aacgattcct gaaaagaaat tgactgcttt tatcggtcca aatggtgctg
    51361 gaaagtcaac ggtgttgtcg atgatcagtc gtttgatacc aaaagataca ggtgaaatct
    51421 atttagacca taacgaagta aaggcttgga aatccaatga attagccaaa aaattatcga
    51481 tcctacgaca atcgaatgaa ataaatgtcc aaatcaccgt gaaagaatta gtagaatttg
    51541 gacgatttcc ttatacgaaa ggaaaattga cgacaaaaga cgaggaaatc gttcaggaat
    51601 cactggaaca ccttgggtta gaagaaatag cggatcaatc gattgacact ctttcaggcg
    51661 gtcaactcca acgtgcgtat attgcaatgg tgctagcgca agacacggat tatattttac
    51721 tggatgaacc tttgaacaat ctagatatga attttgcggt tcaaatcatg cagattttaa
    51781 aaaatttagt acaagaaatc gggaaaacaa ttgttattgt tcttcatgat atcaactttg
    51841 ctgcaagtta tgcagacgaa attgttgcaa tgaaagatgg acagttattt acgcaaggaa
    51901 cgacccaaga aatgataaaa aaagatgtat tggatgaatt atacgaaatg gacatacgga
    51961 tttgtgagat tgaaggccgc agattctgtc tttatttcta aaactaacat taggagagaa
    52021 gagatgaaaa aattagtagt aggtatcttg attctagcat catttggttt agcagcatgt
    52081 ggaaatagca acaacaccag tcaggcagac acaaaaaaaa gcagcacaca aactgaaact
    52141 acattgacga taacagatag taatggagac caaatcgagg tgccaaataa tccagaaaaa
    52201 gtcgtcgtat tcgacaatgg ttctttagat acgatggatg ctcttggtgt tggagataag
    52261 gtagttggag cagctacaag cagccttcct gagtatcttt catcctataa aaaagtagaa
    52321 tcagcaggtg gaataaaaga accagactta gaaaaaatta atcagcttca gccagatcta
    52381 atcatcattt ctggccgaca aagagatttt caaaaagatc taagtcaaat tgctccgacc
    52441 attttccttt ctttagatgc gaaaaatcca tgggaatctt tccagcaaaa tgtcactgct
    52501 ttaggggaga tctttggtaa gcaagaagaa gctaaaactc aattagagga attatctagt
    52561 gcaatcgatc agacgaaaaa gaaagcagaa gctactgaca aaaaagcact agtcacactt
    52621 gtgaatgaag ggcaattatc agcctacgga tctggttcta gattcggttt catccatgat
    52681 ttatttggct ttgaacaagc agatgatcaa atcgaagcat ccactcacgg tcaaagtgtt
    52741 tcttatgaat atgtgctgga aaaaaatccg gatatcttat ttgtagtaga cagaacaaaa
    52801 gctattggtg gagacgacag caaagatgat atttctgcca atgaactggt agcacaaacg
    52861 aatgctggta aaaatcagca gatcatctcc cttgaaccag atgtctggta tttaagcggg
    52921 ggcggtttag aatcaatgaa actgatgatc gaagatgtga atcaagcatt taaatagcat
    52981 aaataacaga ggattaaact ctcatactat gtaacaataa tgtttcttac attcttaaat
    53041 agcaagagcc tatcctcaaa gaagttatca aaaaccatcc gtaaaatcgt attgatgatt
    53101 ttacggatgg tttttattta tttgagaaat cttttttcaa cgtgaattca ttatctacat
    53161 catacgggtt gattctagaa tggggagtgg caaaaaatag tgtgatccat tttttcagca
    53221 tcaagatcgc ctcctttgat ttgaatcaaa ggtacaaagc gaaacttaga taaaacttaa
    53281 atttagatat ttttattttg taccgatctc ttctttaaac gatgttccat ctgctgcttc
    53341 tcggcaataa gtccactaga ctagaaaata tgagaagcta ttttctgtcc agcgttctta
    53401 ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa cgatgttcca tctgctgctt
    53461 ctcggcaata agcccactag actagaaaat atgagaagct attttctgtc cagcgttctt
    53521 attactcaaa gcaaatcgca gttgtcacaa tctcttctaa acaatgttca atcagctgac
    53581 cttcggtatt agctcaaagc actgatttca caacctctat ttaggcatgt gtctcagcaa
    53641 gcggttgata gttgatgatc tgcatttttc gataaaaatc ggcgggaagc ttactccacc
    53701 gttttaataa ttgatagaaa taactctctt ctgctttgat tttatactcg cttaatatca
    53761 atccaaaact attcgttttt tttgaagcta attttttata aatatccaat gctttggttt
    53821 tatcttcatt gacaaagagt gtttttactt caatataaga accctcgata ttttgtgttt
    53881 cttcgataaa atagatgttt tttatatatt ccttcatagt gattcctcca aagaagtctt
    53941 ttatttgata agtttactct accgaagagt tgttaataat ccgtgaacaa aaagtaattc
    54001 tttttccaat agttgttaaa ggttttttat tttttatagt attttttgtt atttaagaaa
    54061 ggaataaggt taaacaaata acaggttgct ttttgggtct ttttccgttc aagaaactga
    54121 acgaagaaaa gggaaagttg tctcttttgt gataagagaa atcataataa acgaatgact
    54181 tactttccaa taaattgaga acagtcagaa ccagacaaat tagttgcatc tgatgaataa
    54241 agtgattatt ctatgacatg aggtgataca gatgaaatta gaagtgacaa aagaagcaca
    54301 agaagtattg aagaataaat tagaagcaga cgatcaactt ttattagata tcgaaaacgg
    54361 tgacggtcca tttgcagaaa gccaagtcag ttgccaattg gatacggcat ttcgattgat
    54421 cattgtcaaa aaagatacac aaacagatct aagtctttat tctgtagtgg ctgatacacc
    54481 agttggacca atcaaaatca aagacagtgc aatactttac atggatgatc catccacact
    54541 tgctttagaa ccaacttata atagtttaca attaaaagga ccaagcggct tgagaaaagg
    54601 caacttgcaa gttgttcgaa aagactagag ggataaaatg ggaaaattgg cgatcatcag
    54661 cgacctacat gtggacatca ataaattcgg cgaatcagag ctgatgcagc tttggcaagt
    54721 tttgcaaaag cacaagatca ctcggcttca tctagccgga gatacggcta ataaagtaga
    54781 ccgttgccta gctgttgtcg aatttttcgt caataaagga ttatctacga catttcattt
    54841 cggcaatcac gagttggcag atgtgcccaa tgaacagatg atggaccatt ttccagaccc
    54901 acatttttta aatgaacggt atattgcttt aaatgagcag accgttcttt tagggatgaa
    54961 tggctggtac gactatcagt tttccgaatt gaaagattac gaggcaatcg tacgaatgaa
    55021 gcgtttgtat tggtatgatc ggttcatcca gcgtgggaaa acagatctcg aggtcaatgc
    55081 agaaatgctt gcagctgcaa aaaatttgct agaccagctg gaagcaaaaa aacttgaggt
    55141 gattttatcc actcatttcg ttcctaaacg ggcatttatc atgtatcaat ctgctcctta
    55201 tgagcgttgg aacaaattaa atgcattttt aggatcagaa tcattcggag aattacttga
    55261 ccgttattca aatatcaaac aagtagtttt tggccatacg catcgtcgct ttgaagataa
    55321 atccatcggt cacacgattt acagctgcag accttttggt tattattatg aatggcagct
    55381 gacccgagat tttgtcttga aagaacagtt gctagacagc tatgatccta tgaaattacg
    55441 tgtcctcttg cgtgcccatc acccagcttt tcaggcctat caaacacaac atttgcaaga
    55501 ggaatttgaa caagcgatga caatcgttcc gtattgagac agcattagta atgtgtaaaa
    55561 gaaaatacct tgtaaaacat aaggataagt aagagcagta gatccattta tcgtggatat
    55621 gctgcttttt ttgcggaaaa taatcagcga atgtttattt gatcggatga tttgtaactc
    55681 gcagagtact agatgcaagc gtgtattctt tttttgaacg ataatcacaa aaaaaatata
    55741 atatacattt tttatttaat tataattaat attgattgaa gtctaggcag tcaagtcaca
    55801 ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag ctgtatttct
    55861 agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct gataatcatt
    55921 tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt cataagtatc
    55981 gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt aaataaagaa
    56041 agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat gttattcagc
    56101 atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga atataacaca
    56161 gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt tgatccagag
    56221 aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg aacaggaggg
    56281 gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat ttctactgcg
    56341 gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa accgacatat
    56401 gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt ctctcaacca
    56461 gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa atttacgaaa
    56521 gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa ttctgaatta
    56581 acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg aacaggtgtg
    56641 gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc ggtacagctt
    56701 tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt agtttggaca
    56761 ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata aatacgtagt
    56821 catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa atttgtttgg
    56881 atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt gaaaaagagg
    56941 aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat catagggtac
    57001 tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag caaactcact
    57061 tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga ggatttaagt
    57121 atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga caaacaagga
    57181 ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat tatttctatc
    57241 gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa tgggaagtta
    57301 ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa taagaagatt
    57361 agtttactct cggattttac atttaaatct tatttatact taggaaatca acgagataga
    57421 gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag taatcccagt
    57481 caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc tggccaacct
    57541 tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg ttcttctgat
    57601 cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc ttttgtcacg
    57661 cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt agctcctaca
    57721 tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga gcaaagaagt
    57781 cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga tctcattagg
    57841 cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac tttttttcaa
    57901 gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc tgatgtaaaa
    57961 gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa gataactatc
    58021 agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca gactagtatc
    58081 gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa tcaaattgat
    58141 gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga ttattttatt
    58201 gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat tcctgaaaaa
    58261 gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca atcgaatgaa
    58321 ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta taaagataaa
    58381 gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg agagaagtat
    58441 aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc gaatacagaa
    58501 ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg caaactttat
    58561 ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag tagaccatta
    58621 agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc ttttggaagt
    58681 tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga gcttccagaa
    58741 gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc tgttacgatt
    58801 ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc tacagctcat
    58861 cgtggaatca gaatagatat tcctgtagaa aaccaaagaa tcggaacctt tgaggggaaa
    58921 ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa tataacaaaa
    58981 ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca gagacaagat
    59041 tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga ccaaaacaac
    59101 aattatttat aacactccta gttattttag gggcactttt taacaatata tcagtgtcag
    59161 ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc gacaagagaa
    59221 aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa gcggaattga
    59281 gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca accaccaatt
    59341 caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc ctgatctttg
    59401 atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa agtgtccaaa
    59461 ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg gctggtggga
    59521 tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat caaagcttat
    59581 cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca ctgaacgaag
    59641 ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca agaaatgtca
    59701 tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt attgaaacaa
    59761 aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa ggattgcaga
    59821 ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg ctaaccccag
    59881 gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga aaattttcga
    59941 gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa aaagatttta
    60001 caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt aaaaaagaca
    60061 ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta ttatgcatac
    60121 ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat aacaaatagt
    60181 aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa tataccattt
    60241 tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt gatcgcgaga
    60301 aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg tatattatac
    60361 aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat ccccagctag
    60421 ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg aattatgagt
    60481 tttttttaag caaagaagat cacagaagtt attcattact taaatattta gaagcaagct
    60541 caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg acatttctct
    60601 tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta gagaaaaatt
    60661 tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa tgttctagca
    60721 aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta ttggctttct
    60781 ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg agttattctg
    60841 tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa attttttttg
    60901 aaaagagaaa gttg
//
LOCUS       DAFEIE010000008        59673 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFEIE010000008
VERSION     DAFEIE010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.008"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(456..1766)
                     /locus_tag="LP345_000603"
     CDS             complement(456..1766)
                     /locus_tag="LP345_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL1759410.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1778..3196)
                     /locus_tag="LP345_000604"
     CDS             complement(1778..3196)
                     /locus_tag="LP345_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1759411.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3436..5004)
                     /locus_tag="LP345_000605"
     CDS             complement(3436..5004)
                     /locus_tag="LP345_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL1759412.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5008..5418)
                     /locus_tag="LP345_000606"
     CDS             complement(5008..5418)
                     /locus_tag="LP345_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBL1759413.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5415..6338)
                     /locus_tag="LP345_000607"
     CDS             complement(5415..6338)
                     /locus_tag="LP345_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBL1759414.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6335..7213)
                     /locus_tag="LP345_000608"
     CDS             complement(6335..7213)
                     /locus_tag="LP345_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBL1759415.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7200..8537)
                     /locus_tag="LP345_000609"
     CDS             complement(7200..8537)
                     /locus_tag="LP345_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL1759416.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8540..9643)
                     /locus_tag="LP345_000610"
     CDS             complement(8540..9643)
                     /locus_tag="LP345_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL1759417.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9717..11225)
                     /locus_tag="LP345_000611"
     CDS             complement(9717..11225)
                     /locus_tag="LP345_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1759418.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11191..11883)
                     /locus_tag="LP345_000612"
     CDS             complement(11191..11883)
                     /locus_tag="LP345_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL1759419.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11905..12879)
                     /locus_tag="LP345_000613"
     CDS             complement(11905..12879)
                     /locus_tag="LP345_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1759420.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13179..14051
                     /locus_tag="LP345_000614"
     CDS             13179..14051
                     /locus_tag="LP345_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1759421.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14509..16707)
                     /locus_tag="LP345_000615"
     CDS             complement(14509..16707)
                     /locus_tag="LP345_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759422.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16939..17931
                     /locus_tag="LP345_000616"
     CDS             16939..17931
                     /locus_tag="LP345_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1759423.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17991..19412
                     /locus_tag="LP345_000617"
     CDS             17991..19412
                     /locus_tag="LP345_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBL1759424.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19405..20904
                     /locus_tag="LP345_000618"
     CDS             19405..20904
                     /locus_tag="LP345_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBL1759425.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20943..22337
                     /gene="uxaC"
                     /locus_tag="LP345_000619"
     CDS             20943..22337
                     /gene="uxaC"
                     /locus_tag="LP345_000619"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBL1759426.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22496..23179
                     /locus_tag="LP345_000620"
     CDS             22496..23179
                     /locus_tag="LP345_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBL1759427.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23181..24017
                     /locus_tag="LP345_000621"
     CDS             23181..24017
                     /locus_tag="LP345_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL1759428.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24028..25782
                     /locus_tag="LP345_000622"
     CDS             24028..25782
                     /locus_tag="LP345_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759429.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26058..26399)
                     /locus_tag="LP345_000623"
     CDS             complement(26058..26399)
                     /locus_tag="LP345_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL1759430.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26467..28638)
                     /locus_tag="LP345_000624"
     CDS             complement(26467..28638)
                     /locus_tag="LP345_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL1759431.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVVYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGATETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28807..29706
                     /locus_tag="LP345_000625"
     CDS             28807..29706
                     /locus_tag="LP345_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL1759432.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29777..30634)
                     /locus_tag="LP345_000626"
     CDS             complement(29777..30634)
                     /locus_tag="LP345_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1759433.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30619..33321)
                     /locus_tag="LP345_000627"
     CDS             complement(30619..33321)
                     /locus_tag="LP345_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBL1759434.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33334..34623)
                     /locus_tag="LP345_000628"
     CDS             complement(33334..34623)
                     /locus_tag="LP345_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBL1759435.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34773..35819
                     /locus_tag="LP345_000629"
     CDS             34773..35819
                     /locus_tag="LP345_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1759436.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35821..37974
                     /locus_tag="LP345_000630"
     CDS             35821..37974
                     /locus_tag="LP345_000630"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBL1759437.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38447..39898)
                     /locus_tag="LP345_000631"
     CDS             complement(38447..39898)
                     /locus_tag="LP345_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1759438.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39895..41619)
                     /locus_tag="LP345_000632"
     CDS             complement(39895..41619)
                     /locus_tag="LP345_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1759439.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41612..42226)
                     /locus_tag="LP345_000633"
     CDS             complement(41612..42226)
                     /locus_tag="LP345_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL1759440.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42571..44028)
                     /locus_tag="LP345_000634"
     CDS             complement(42571..44028)
                     /locus_tag="LP345_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1759441.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44069..44989)
                     /locus_tag="LP345_000635"
     CDS             complement(44069..44989)
                     /locus_tag="LP345_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1759442.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(45001..45948)
                     /locus_tag="LP345_000636"
     CDS             complement(45001..45948)
                     /locus_tag="LP345_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1759443.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46427..47146)
                     /locus_tag="LP345_000637"
     CDS             complement(46427..47146)
                     /locus_tag="LP345_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL1759444.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47195..48841)
                     /locus_tag="LP345_000638"
     CDS             complement(47195..48841)
                     /locus_tag="LP345_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1759445.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49020..49610
                     /locus_tag="LP345_000639"
     CDS             49020..49610
                     /locus_tag="LP345_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1759446.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49702..51207
                     /locus_tag="LP345_000640"
     CDS             49702..51207
                     /locus_tag="LP345_000640"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBL1759447.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51291..52643)
                     /gene="celB"
                     /locus_tag="LP345_000641"
     CDS             complement(51291..52643)
                     /gene="celB"
                     /locus_tag="LP345_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL1759448.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52643..53161)
                     /locus_tag="LP345_000642"
     CDS             complement(52643..53161)
                     /locus_tag="LP345_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759449.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53177..53503)
                     /locus_tag="LP345_000643"
     CDS             complement(53177..53503)
                     /locus_tag="LP345_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBL1759450.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53516..55495)
                     /locus_tag="LP345_000644"
     CDS             complement(53516..55495)
                     /locus_tag="LP345_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1759451.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFFNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55516..55830)
                     /locus_tag="LP345_000645"
     CDS             complement(55516..55830)
                     /locus_tag="LP345_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBL1759452.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55998..56291
                     /locus_tag="LP345_000646"
     CDS             55998..56291
                     /locus_tag="LP345_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBL1759453.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56369..57481)
                     /locus_tag="LP345_000647"
     CDS             complement(56369..57481)
                     /locus_tag="LP345_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1759454.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57868..58047
                     /locus_tag="LP345_000648"
     CDS             57868..58047
                     /locus_tag="LP345_000648"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759455.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58241..58411
                     /locus_tag="LP345_000649"
     CDS             58241..58411
                     /locus_tag="LP345_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1759456.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58835..>59673)
                     /locus_tag="LP345_000650"
     CDS             complement(58835..>59673)
                     /locus_tag="LP345_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1759457.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
BASE COUNT        17832 a        12199 c        10436 g        19206 t
ORIGIN      
        1 gtttattgtc ttgaattgaa tcaagacgcc ctacacattt ggtttgtctt actttgttca
       61 gttttcaaag gtctacttca tcgagagtgt ttcccgattc atttttggct gccgcagcaa
      121 cttttatatc atatcagaga gacaaacgat tgtcaactct tttttaaaag tttttttcga
      181 tttcgttttt cgaaatcttt cagcaactca tttatcataa cttatcgttt gttatttgtc
      241 aagaactttt ttgaagtttt tttcgataga atcaagcttc gcaagtggtt ctttttaacg
      301 acttagttat cttatcacgt ctaaaaacat gtgtcaactc ttttttggaa ttttcataaa
      361 atgtttcaat gaagcgcgac aacgttgttt aatatatcat taaaaaaaat aaaggtcaag
      421 ctaaaatatt atttaagctt gaccttatta taatttcaac gattgtcaaa agtattgttt
      481 gcagctgtgt tgccagtttc tatagataaa tcacagcttt tgaaacataa gttttgtact
      541 gcttcgattc gcccgaattc ttttgcagtt atttggcaat gagaaaagca gacatcttct
      601 ataggctttt caggaaatgc tactaaatca aaagctcggg aaggaagtga gtaacctgga
      661 gaaaggcatg cctgtacgtt tttgatgtgt atgtctttga ctttcgtcat ttgctttgat
      721 tcaggtattt cttcagccac tgcttgccaa ctttctggca tttgagcaag gtcattgcta
      781 ttttttctat tgtattcatt atgccagtcc attatccaag aaaaaggaaa ttgtacatca
      841 atcatattca gattttctac cctgatattt tcgatcactc cccctctttc ttttgaagat
      901 ttcattcgaa taccacagtc tgactgaaaa aaatcgatat cgtgaatata tacgtcacta
      961 actccagcac taacttcgct accaatagtt acaccgtatc ctgaacggat tttacatcta
     1021 gcaacctcga ttcttgatga ttttcgattg actcttgcac cattgccatc tctgccagac
     1081 ttaatagcaa tacaatcatc accacaggcc aaatcacatt catagacacg cacatttgtt
     1141 gaagaatcaa tatcaatccc atctgtactt ggtccatcat tgttgcggat gattactttt
     1201 tctactaata catcgttaga ataagtgatt tgcaagttcc aaaaacctga tttctgaaaa
     1261 atcaaatcac gaacaacaac atgttctgca tgatacagta aacaagcgcg tggacgttta
     1321 atagcataat ccgcaatcca acgaagtccc ttttgatcgt attcagctct tgtcccgctt
     1381 ttttgatctt ttccccaata cagctcccac caatggtctc cttgaccgtc gattattcct
     1441 tttccttcta taagaatatc tttcgccgag agaacattca aaatcgctgc tggccatttc
     1501 atttctacgc cggctactcg tgtatcgatt tctggaaatg cttcgatatc tgttctcccc
     1561 ttgaggactg caccttcttc aaagataaga tgactcttat cttttaaaaa aagggctccg
     1621 actaaataaa tgccttttgg aataaataca ggtaagtgtt ctttcgcacc ttgatcgatt
     1681 gctttttgca gtattattgt atcatcttgt tgagtgtcgt ttgttttaaa gttcaaagca
     1741 ttgataatcc ctttttttgt ccgcaatacg tttctcccta tctttcattg atttttttca
     1801 attcttcacc aataaataca gtttttgaac gattcagtgg gtaacctact agcaaaatga
     1861 ttgcggatac aaataagcag aatgctggta acaagtttgc catcgtataa atcctttctt
     1921 gtactaaaac tgattggatg gctccacctg ttgtagacga ttggtaacca atgagtgcca
     1981 gcataaatcc gcctaccgct cctgcacatg cttgtcctac ttttctcgca aaagaattta
     2041 ctccatatac tgttccatct tctcttaagc ctgtcttata ttgatgataa tcaatcacgt
     2101 cagtaatgaa tgcccagacc atcaaattga ataaaccaga tcctaaagta gcgataaata
     2161 aaagaatcag atatacccat gcatttgtta tatgaaggaa atacatcagc aagtacatac
     2221 atgaagaagc aagtaacgca aatacgcttg cttccttttt accaaataat tttgtcagct
     2281 ttgtagcaaa tggtgctaaa actactactg ttccgtaagt aaataaaaga gcaacagaca
     2341 ttgcttgttt attatggaag taatcattga ataaataagt catattcgtc ccagctaaaa
     2401 tctgattgat cacaatgaaa atgtcaacaa tgactaaaat aatcagtgct cgattagcta
     2461 acaaaccttt taccaactga gaagcagata ctttttcgtt tttgacaact cttactcttt
     2521 cagtagtcaa tttacaagtt aacatatatg cgacaaatgc tattgcagca catccgattg
     2581 aaatccaaaa gaaatgattc cctgaaacga cttgttgtcc actcttgtta tgggtataca
     2641 ttaaaatcgg aatgaagaat cctgtagttg atccgccaat cgcagaacca atgcttcgga
     2701 acgtggacaa cgaggtgcgg tcattaggat ttgagctaat tgctgctgcc attgctccat
     2761 acgggatatt gattgttgag agaaaaatcc cataaacaat gtatgaaaca aaaatataag
     2821 caatcttcac cgtcattgga agatgttgga cgaatggcaa aaacaaaatg acagtcacta
     2881 agcaaaatgg atacttcatt tttctgatcc aaggaataaa tcggccagtt tctgttaact
     2941 ctgagacatc acataatctt ccaaccatca catcagcaaa cgcatccaaa attctcgaaa
     3001 tcaagaataa cgtacctacg attgcccctg aaacgccaag aacattcgta taataaatca
     3061 tcaagaaact attgactaaa cctaaaataa aacagttacc tagatcaccg aacatgtagc
     3121 ctatcttatc ggaaatccca aattcctttt tttctttttt tattgtattt gctgtaacag
     3181 cattttgtga aagcatttga attcctccta cctcttctag taaacgtttt caaaattata
     3241 actctttttt tcttgttttt atattcacaa tgttggcttt ttattgcatt atcttgacag
     3301 ataaaaaaca aaaaataatc taaaaacatt gatgcataag attgataact ttttttacat
     3361 aacaatatat acaaacaaaa aaattcacta actagtgaaa ataagttagt gaacctcatt
     3421 tattaaagaa ttaaattaca gatgatcttt tccatcatac ttgaaaaact caaaatcagc
     3481 ataacttcct ctttttttat ttagatcatg cactgctatc ccgataaaat ttccagtaaa
     3541 ccctcctgag agtatacaca tgtttttttg cggacctact ttcttccatt cttcagttga
     3601 tacgtctttc aaatgaaact gtgctgtctc tttctttaca gtgactttca aaaaagtctt
     3661 cttttctgtg agtggaatcg tccaatcttc tatttgtgct actccgtttt ctgattctat
     3721 catacgtagg cattttccct tgtcctcatt ccaagtaaca taacaataaa tataattgga
     3781 ttcatttaag tacagtacca gtccagccat ctgattaaaa ttattaggca tgtattcaaa
     3841 tgctgtctcc gcatcaaaag taaaatccgt ttgccgaata gctaacaaat gatgttcgaa
     3901 ggtagattga agagattcac cggaaatcag acgtaaaaaa cctggtctac attttgtatc
     3961 acaccaatca gcatttggca aaatgcgtct ggcattccag ttcttcttta gctctccttc
     4021 aaatgtatcc ataaactgat gatctttttc ttgttgtacc tcttcatttg tctcaatcat
     4081 tatttcttcc atcggagttg tctggctatc tttaagtctt aaccaatcgt cggacgtcca
     4141 atacacttct tgaatagcgg tttctcttcc caaaatagcc gcaccgttta atggtctggt
     4201 acaaagatat gtcatgtacc atcttcctga cggggtttgt actaagctcc catgtcctgt
     4261 acattgcaat gtagaagcag gtttgtcact agctgtcagc ataggaaaac caggatcaag
     4321 ctcgtaagga ccagtaatat tctttgctcg gcaaactgta actgaatgtc ctcttcctgt
     4381 accgccttct gccgtcatca aataataata cccgttacga aaatacaaat gtggtgcctc
     4441 cgttttcgct aattctgtac ctgcaaatat tttatagatg ggaccatcaa gcttcttctt
     4501 ctctgcatca tattcttgta atacgatacc gctggattta ttcggtgtgt ccagacgata
     4561 atcccatagt tcattgacaa gccatttttt tcccgtttca agatcatgga acaaagaagg
     4621 atcaaagccg ttactattta aataaattgg ttcggaccaa ggacctgtga tctcagatgc
     4681 agtgatcaaa taattgtgga catctttaaa cggacggcct gcacttttga catctgtgta
     4741 aacaagataa aacaatccat cagcataact gatctgtggc gcccatatac ttccatttgt
     4801 aggatttcct tgcaaagata cttgagtggt caaaatatcc gttgtatgtg accagttgac
     4861 taaatttttc gactcatata ctcggattcc tggaagccat tcaaaagagg agacaataat
     4921 gtaataccgc tctttcactc ttaatatatt aggatctgga ttgaatcctc ttaaaatagg
     4981 atttttcact ttgatagtct gcatgattca ggctcctttt ctcattctta ctcgatataa
     5041 actgaatgcc ccagctgcga aataaaaaaa tgcaaaagga aacgcaataa actgagtgcc
     5101 aatcaacaat atgaatcctg ttataaaata caaaccagtg gcagttgtta agtattttcc
     5161 tttagcagtc aaaaacaatg ctactgctaa aaaagcaagt gaaataaaca acacaacggc
     5221 aaacagacca gtcatgtcct gtaataatcc aaatgtattt tctaaagaca aagttgaatg
     5281 atctacagca agcgactgat aacttttttt aaactctgac gcagacatat tacttaaagt
     5341 aactgctaac ccgccaaaga aaatcaaaga tagactgcca ccgaccattc ctagcaatag
     5401 ttcccatttt cttttcattt ctgaaccccc tgcttttcta aatgtatcca ttcaggtctt
     5461 ttgatcgatg tttcataatt gttattacgt tcagagaatt tgacagtctg ttcatttttc
     5521 ttgtcatccc aattatccca accagttggg tgaacatgcc cacctatctt acacgcttca
     5581 aataagacat ttgcatacgg acgccacggt cttcctaaat agacgtttct agtatcaggt
     5641 tctgcagtca aggtacagct ttcaaaacga taccctgttt tttgattttt cggcgtagat
     5701 gctgctgtga tgtatccagg atttttactg gctaagctat ggatatgaca ctgatgaaaa
     5761 acggcatctg ccccaccaaa tatgaaatcc accgttcctt caatccagca atattcatag
     5821 gtctgacgac aatactcagg attggcagaa gccggtgtac aaaaaggagt accatctttt
     5881 tgcaaatcag gcaacggacc cgtgcataag gtatcctgat aaccagatag tcgacagttt
     5941 tttaaagata cgcgatctcc tgaattgaat aaagcaacag cctgtcctac cttttctcct
     6001 ggacctgctg tattttcgat gtgaagattt tctaatacga cattcgatcc ttctaagaaa
     6061 aaagtagcac ttcggaaagt ccctaactgg ctaccgtcaa gatactcctg ttttgcaaaa
     6121 cgattaccgg agataactac tgttcctgct cccacaagtt taaaattgga taatctgctt
     6181 tctatatatt catcatatct tccttctttt actatcaaga cctttggatg gctatccggc
     6241 aggcctgcca aataatcgat tccttcttgg atagtttcaa aatccgtcgg ggtatctata
     6301 gcattctttc caattatcag tttgtctttc atcctcataa atgctccctt atgaattgtt
     6361 tccaaatatt tctcatttct tgtgtttcca tatgaccgcc tgttaaagaa aaagaagaaa
     6421 agttttctgg actacccatt gattgatact ttttgtccag cccttttctc agcttcagta
     6481 cgccttcgtc caagcacatc gtatcgtttt ttccaactaa gctaagacga gggcgcggag
     6541 cgattttttc ttggattgct aacgttgtat aagctgtcaa tagatttggc acatagtaat
     6601 aaaacccatg atgatctagg cggcgatgta gcaaaagtat ttcgatgtcc acctgtgccg
     6661 ctagatcaat acaaactttg acacgagaat ccaatgctgt cacccaccag cttaataagc
     6721 ctcccataga aagaccaatc gttgcgagcc gttgagtatc tgtgtcttcc cttgtctcca
     6781 aataatcgat caagctgatc acatcataaa tacgcattcc ccataacgtt tttcctgtta
     6841 ataaaaattg tttgaacaac tcgctttcag aaatacctcc gcgttcttca aatccccaag
     6901 catcaatcga ccaaacagca tatcccattc ctgtcagtac ttctgcaaaa gatggagaag
     6961 ctaagtaagg agcaccatgg atcaattcac ttttcccgac tgaaaaatct ccgccgtgag
     7021 aatgcaggta aaggaccggc ggaaacggtc cttctttttc tggataagca tagagggctg
     7081 gtactgtttc caattcattt aagtacaatt gatagtattc aagcataaaa ccgttttgtt
     7141 tttctcggta taatcgtttt ccactagggg tatgtctgct agatggagca cctaaaaaat
     7201 cattcaactg cataagcaaa gtttttacga acaaccagtt catccatatt ttctgattga
     7261 tttgattgga atttctcaat actgatttct ttagtatttt ctaatagaaa tgctggtccc
     7321 tcgtgatttt caatcgacat ctggttaaag gaaaccttac ccgcaaagcc aatataaaat
     7381 ccttgtctgc tcatttcctc tattcctgtc atcatagcag gaacaccggg aactgcatct
     7441 tgggccatcg agacatcgat attgtcaaat gtgatttctt gtatgaattg ttccgctaat
     7501 ccataaataa aacctgcaga agcatggaca ttccttgccg tgatattcga aaaatggatc
     7561 cttctgaatg ctggtgtccg ttcatctatc ggataagcct ttttttccca tacatacggt
     7621 tctttccctc gcggaccaca gaaataataa agattcagta taaatggaca catcacatta
     7681 tccatgacta tattggatac tcgaatatct tcaacgatcc cgcctcgacc tcgtctagat
     7741 ttcaatcgta ttcctcgatc agtttcttgg aagatacaat ttgaaatggt aatattacga
     7801 atactaccac tcatttcact tcctaatacg acaccgccat gtccatggac catcgtgcaa
     7861 tttgtgatcg tgatattttc gcaagcgatc ctttcgtacg tatcttcagt ccctgccttg
     7921 attgcaatac agtcatctcc cacgtcaata tggcaattac taatacgcac atttttgcat
     7981 gattctggat caattccgtc tgtatttggt gaatccgctg ggttcaagat cgtcaagtta
     8041 tcaaacgttg cattactgca aagaatcggg ttgatcgtcc aacttggtga ctggatcaat
     8101 ttaatatctt tcacagtaat tcgatgacag ttatggaaac tcatcaattt aggacgagga
     8161 taagcgagat tatctggttc atttctaaaa gtatgccacc atttttttcc atttccatct
     8221 aatgtaccga aaccagtgac agagatgttc tctacatttt gagcatagat acaggaagca
     8281 taaacttttc gatggactcc ttcccaacgt gaatgaacaa caggataatc ttttggatcg
     8341 tcagagaatt tcagaaccgc tcctgcgctt aaatgaagtt cgacattgct ttttaaaaat
     8401 aaagctcctg ttagaaattc acctgctgga acaactacgg tcccgcctcc gtcacttgct
     8461 gcagcatcaa tggcttgttg tattgcttca gtattcaatt catcaattga tgcgccaaat
     8521 gtcaaaatat catacatatt tataatgcct ccacttcaat caatgcttgc aagaatgcac
     8581 caacgccttt ttgatcatta caaataattg gttcactgat gtagtaagca tatgaaccat
     8641 ctcgctgatc tgctccgcct aaccctgcta cttgacagtt tttattcaag ttcagccagc
     8701 cttcttttgt ttccagaaca aattcatcaa gtaatccttg atgtgatttc ttcacttgtg
     8761 gaagccattc ttctttgttc agcagtccca aacgtattcc tttagccatt gcgtaaacaa
     8821 acatactact gccggaagct tccagataat ttcctttccg ttttgtttct gttgttactt
     8881 gataccatgt cccgctgttt tcttcttgat atggaagtaa tgcagccagt gtcttttcta
     8941 gaatttcttt cagcaaagaa caatctgttt cttcatgaag taattcatag gtatctgctg
     9001 cagccatcaa ataccagcca atcgatcggc tccaaaaatg atgggataga cctgtttttg
     9061 gatcagccca tggttggacc ttcttttcat cccatgcatg aatcagcaaa tttgtttttg
     9121 gatcgaatag atgtttataa ctgatttcaa actgtctcaa aacatcttgg taatcttttt
     9181 cttcactaaa attctggata aattcagcat aaaaaggaga acccatatat aagccatcca
     9241 accaaatttg ataaggataa atttctttat gccaaaaagc tccttcggat gtgcgtggat
     9301 ggtttgccaa ctgctgggaa aggagttctg ctgctttttt atatttttct tcgcctgttt
     9361 ctttgtacaa taaaaagaaa agctttcctg tatttacatg gtcgatattg tattcttcaa
     9421 cgctgtagcc acggatcgtt ccatcttctt gcacgaaata gtcgatattg tcttttatga
     9481 aatcaaaata aattttttct tgggttcgtt cccaaagtaa ttggaaccct ttaagtacga
     9541 cgccatagtc ataagaccat tttcctttat accacttttc ttcatataag cgaggtgttc
     9601 tttccatgat actttttgct aatttctttg accagttttc cattatttgc tctcctttaa
     9661 aaattaaaat aggatttggg acaaatacca agaagtattt gtcccaatcg tctatattac
     9721 tgtgccgctg ctttgtatgc ttcctcgtac tcttgtgtga ttcgatcgcc tccttgtgct
     9781 ttccagtctt ctacagcttt tttgaatcca tcttcgtcaa gctgtcccat gatgtattgc
     9841 accgtagcat caatgacgat tttttcaatt tctgatccta cttcattgtt cgtcggtgaa
     9901 tccaatggca cagaaggatc cattacagca aattcttcat tttctttgat caattgatta
     9961 gagaattctt tttcagggtc tgtatctttg aaagagaacg tcacttcact aggacgagag
    10021 cttgataacg gttgcacctc ttgttgccaa agatccatat cgataaattc gatagaacca
    10081 tcatcattca attcataatg cgttccttcg ataccgccag tcatcaattt atacacatct
    10141 tcttctaaaa gatcatcaac aaattgaagt aatttcttca attgtgcttc gtcttttact
    10201 tgagatttgg gaaatgctag caagccgcca ataccatttc cttctgacca aacatgataa
    10261 ccgccgcctt caccatctga gatcttgttt acaggcacta attccatatc atcttgaata
    10321 ccttgaccca tcgtcttcag attcttgata tccaccattc cagtgtagat tccagttctt
    10381 ccttgtgcaa attgttcttg ctgatcagtc ttttgggtaa ctgcaaagtc ttgtgccaaa
    10441 tagccattct caaatagatc tcttgaaaaa ttcaaagctt tcatatactc ttctgtatca
    10501 aattctggag tgaatttgcc attatcgtct acagcccagc catttggtgc tccaaaataa
    10561 gaagtgaaaa gtttaaagct ggtataacga atatcactag gcgcacgatc gccaaaacca
    10621 actgtgtcgt ccacaccatt tccatcagga tcgttttctg taaattgttt agctacttca
    10681 taaagctcat ccatggtagt tggaacatct agtcctagat tatccaacca gtcttttcga
    10741 atgactaagc cagcacgagc gtagtctttt tgtatcggta cgccgtacaa ggcaccgtcg
    10801 atactcgcag cttcgattct atcttcagaa atttgactta aatttttata gtcttttaaa
    10861 tattctgata catcccagaa tacgcctgat tttaacgcat tgcggacaga agagtttttc
    10921 aacatcgcaa tttgaagtgt aacgatatct cctagttcat cagaagccaa tgcagttgtt
    10981 aatctttctt cttttgaagc atcaggaatc cagttgaatg tcagttccgt atcggttttt
    11041 tcttcgatca agttcacaat cgtgtctgta ggcggtgaag catgatgcaa aatatttaac
    11101 caagtgattt tagcttttcc atcttctgtc tctgaagaac tgttacttga actgctgccg
    11161 catgcggcaa gtgctagaat tcctgcaaaa ctaagaccta attttacgag cgttgctttt
    11221 ttcataaatt ttctccttca ctgttttaat aatatttttg ttttcttctg ttttttctgt
    11281 atatgagttc ttccattcca aatggcaaaa tatagaattt gctgtccacg tgactgcgga
    11341 aaagaagaga ctgccaccga taaaggttaa aacacctggc attgtttgga tgatcatcag
    11401 ataaatccct accatactta atatcaacac taatgagtaa tgaagatgtg agaatccgaa
    11461 taaaaatgcc attttcattt tgaaaaaata tcctttccaa tcataatgag ccatgattgg
    11521 gaaaatatag agtgctgaga gcacatatat gaacgcagca atatacaaag cgatcctaag
    11581 ataccaattg tgtatgaaag aaagatccac aagtaaaaca atcccgatgg cgccatatat
    11641 ccagctcatc agcaaggttt cacgatagtt ttctttaaaa tatgtgaagt acgttttcgt
    11701 caaaggaaac gtttcttttg agcgcagcca ttttctaatc actgcaacca tcgcatacga
    11761 tgcaggaccg aaagtaaaaa ctcccaaacc tgcgatgact aaaccgcccc acagaaaatt
    11821 caaataaacc aactgtaaaa tacgatttag ccttccgttt attttatcta atgactgcag
    11881 catatctttc cctctctttc tatcttagta aacgccgtct tctcctagct ttttggcaat
    11941 cttattagct aaaattacca taaacaatcc tacgacccct ttaaacaatc ccattgctgt
    12001 actgaaactt aactgtccat tcttcaatcc agctgtataa atataggtgt cgaaaatttc
    12061 tgcaacgctt cgattcaatg aattcaataa caagtacata tgctcgaacc ctaagtctaa
    12121 tgtctgaccg atttttagaa tcagcaaggt aatgattact ggacgaattg ccggcaatgt
    12181 aacatgccat gttttgcgta agcgtcctgc tccatccatt tctgcagctt catacaactg
    12241 tgtatcgact gcagttatcg ctgaaaggta gatgatcgta gaccagccca actctttcca
    12301 gatcacttgt ccgatatata ctgtgcgtgt ccattcaggg gatgttagaa aactgatttt
    12361 ttcaaatccc attgttgcaa ggaattcatt caatacccct ccgtcaacat tcaaaaatac
    12421 ataagtaatc gaaacaatga ttacccaaga catgaagtga gggatgtaaa tgatcgtttg
    12481 aatcccgttt ttcaatcgtt tgttcgttac ttcatttaat agtaaagaca aaatgattgg
    12541 catcggaaaa aacacgaaga tatttaatcc gaacaagatc aacgtatttc ttaataatgt
    12601 aaagaatgtc ggttctgtaa acaaacgaat gaaatgtttg aaaccgaccc aaggacttcc
    12661 cattattcct aaaaatggtt gataatcttg aaaagcaata acgagtcccc ccataggaag
    12721 atacctaaaa atcaagaaat aaaggactcc cggcagaatc atcacatata aaaatttatt
    12781 cgttttgatt cctgcaatta ttttttttcg tcttctgagc ttttcttctt ttttcgatag
    12841 cgtcagttga aatggttctt gtttctttac actttccata agcccctcct tagttttgtg
    12901 aatgtttgct gcttatgact tcatgataga taactatctg aattacgtat ataatcattt
    12961 ttaccgtaag taaaaacgct tacatagcaa tgatttttgt gctatacaaa acgataaagt
    13021 gtattttttc acaaataaac tacgcatagc aaaccttcta tttttttcta tctgacactt
    13081 agcataggaa atgattatat acgtaatctt tcaccgatga taaattgaac atatagaaac
    13141 agaaacattt aatttatttt gaggaggagc ctatctatat gaaaaagaaa gtctctatag
    13201 gagaaagaag ttttacactt ttcaacaata cgtttctaat tttgctagct ttgatctgta
    13261 tcgttccttt tttaaatatc atcgctacat cttttgcttc tacacaagaa gtcgtcgcga
    13321 aaaagtttat cctttttcct actacctttt ctttagacgc gtatcgctac attctttcta
    13381 cgccgaccat ttttagagca cttgctgttt cgattggtgt tacaggtgtc ggaacgatcg
    13441 tcagtatgtg tgcaacttca ctgatggcct acggtctttc cagaaagtat ttgtttggtc
    13501 gaggtttcgt caactttctt gttgtatttt ctatgttgtt cagcgggggg atgattccaa
    13561 cgttcttagt tgttcgttct ctagggctgg tcaattctta ctgggccatg atcctgcctg
    13621 tggctgttaa tgcaatgaat atgatcatta tgagaaactt tttccaagcc ttgccggata
    13681 gtttggaaga atcagcaaaa atggatggtt gcacagattt tggtgtattt ttcaaaatta
    13741 tgctgccatt agcgttaccg tctattgcta ctatctcgct tttttatgct gttacttact
    13801 ggaacactta tatgactgct attttgtata tcaacgattc atctaaatgg ccgatacaga
    13861 ttcttttacg ccaaatcgtc attgtatcaa gtgggatgca agcagaaagt agtgccgttg
    13921 atgtgattcc accagcacaa acagttaaaa tggctgttat cgttattgca acagtgccta
    13981 tgctgattgt ttatcctttt gttcagaaat attttgtcaa aggagcactc gtaggttctg
    14041 tcaaagggtg attatgtact gaacgcaaaa tggtagttgt gtcagaagtg gtcagcttca
    14101 agaaataaga aggcatttac gaaaattgct tcttaaattt ttgtgaaatt tcggcttatt
    14161 tttcgaagaa tctactcctg gaacaccgtg tatcagaggt tgtgaaagag acgttcagcc
    14221 ttgagcgatg ataaaaactc tcacaaacat tgcgacgagt aacccacagg agcaataaga
    14281 agcgattttg aaaaatagct tcccatattt cacaaaatta tgccttattg tcgatagcct
    14341 gtctcttgaa cgccatttat tcgtaaaaaa gaactgtgac aagacttttg tcacagttct
    14401 ttttgcgtgc ttagccttga aatttaacta tccataaata caaatactag ggttattcta
    14461 acttctttta ttgcttgaat cagtccacaa gaaaaacagc ctcttgattc acaaatattt
    14521 ttttcgatat tctcccggcg taatcgattc cttcttttta aagaaacgaa taaaattttg
    14581 cggatttcga tattgcaatc tttctgcaat ctcttttacg gagaggttag tctctttcaa
    14641 ccattttttt gctacctcta aacgatgatt ttgaacaaaa tcaccaaatt tttctcctgt
    14701 ttccttttta aatacattac ttaaatagtt agggttataa tgcaacctat cagcgatcac
    14761 atctaaagac agatcacgat catattctgt gtagacgata tgcataatat tctccgacaa
    14821 atttttaaat tcatgatcag tgattgcttg agagcattct gtgattggca gaactaattg
    14881 ttctaaaaca agtttttcta gttctttggg atgataattg ttcagtgctt ttacataaat
    14941 ttgtttcatg ttatcaaagt tttttgaatc tactcccaat aactgtccta attgaacgag
    15001 ttcattgatc aagcggaccg aaactacttc ccgactcaaa ggatttttat tttgtgcaaa
    15061 caatgcatca atcaattcat gtactaaatt cttcacttcc tgatttccag aacgaatggc
    15121 ttcaaacaat cgattttgtt cttctatcgg atatctaata agtgtttttt catgagcagc
    15181 aggaacgatt tcctgataaa aaataattga acttggacca gtatttacac gataatacag
    15241 ggcttctttt gcccgatcaa ccgattgctt gctttcattc agcgtttcga accggttact
    15301 gatgcctata ctgatagtta aattcaagta ttcttttaca cgtttttgaa tgagtcggca
    15361 atactccatg acttttttgc ttgcttctgc atcatcttta tccattcgat aaatagtggc
    15421 ttgcatttct tcattcaaaa cgatcggcag cattcgattt tcctttggca caatttccgt
    15481 gatcatgttg ttgatcgcta aaagtagcaa atcacgctcc ccaccgtgac tatcttctaa
    15541 cagatcgatt tgaaccaaag ctgtataata gcagtcattt tgagaactat aaccaaattg
    15601 ctgcaaccgc tgatctagtt ctcgcctttc tactcgattt ctaaataaac taagtacaaa
    15661 tagcgtttcc agctgtggct tttgggtaac taagtgtgca cttaacgctt ctttttctcc
    15721 tatgatccga ctgactgatt gagcgaccaa atctagttct ttcccactga atccttttga
    15781 tttaagattc agacgttcct gtatttgaga aatcggacgg gcaaatctgt ccgaaaataa
    15841 gtaggaaaga agaccaatga gtcctaccag tgttaaagac actgcaacta gcccgattct
    15901 cagattgcgg atcattgcgc caattgcact agagtcaact tctaatctgt aaatccaatt
    15961 attataatct gatttcagta ctatatacgt tttatctttt tctcttatca ctttcagctg
    16021 attgtaatct agatccacgt ccgttaatac agttggttgc tctttatttt ttactgtctg
    16081 agtagtaaaa aggttgccaa cttcgttttc aatagaaagt atgtcttctc cactttcacc
    16141 aacaacttgt tctattgtat gtttctctat cgtagcaatt cccaatgcat atttttcttt
    16201 ttcaaacatt ggcaaagaaa tcaccatttc gattcctttg tttttctttt gccaaaataa
    16261 attatttttg ttatttatgt acttctgttg atacttttca atttcctctt cggtcagttg
    16321 actcaacgat ccattgatta ctccccattt accagccaaa ctgactaaat cataattatt
    16381 atcatccata acaatcgttt ctataaaatt tagttctttc ctgatttcag aataagtgga
    16441 gtaatctgta tatgtcagcg gatgcttgaa tatgtccgag aaatttttgg tcgaaccata
    16501 cgtagaaaac gaatattcaa tcgttctaat tttccattca acgttagttt taacttgcct
    16561 gagcaaattc tttttgtctg ttaaataact cgattcgatc gattcatagg tattctggta
    16621 aatgaataaa ctaaatccta tgacaagtac ggctcctaat aaaaacatcg gtaaaaatat
    16681 tttataaaat actgtacttt tcttcatttt cttcctctcc tccttttaaa ataaaaggct
    16741 ttcatttttc tgtaaaattg atactcatct aattaaatga gcattccccg ctttcaagaa
    16801 tagcataatt aaaaataaaa atccaagtaa tttttaacgt gtgcaatctt ttcatatcaa
    16861 agatctattg acttatcgta gttatcgtaa tatgatgaat gcgttaacaa aaagtgaaaa
    16921 agtaaggaaa atgatggaat ggtaacgatc aaagatgtcg ctaaagcagc tggcgtttct
    16981 catacgacag tttctcgtgc tttgaataac agcagtttaa taaaaaatga aacaaaacaa
    17041 aaaatacgac aactagctaa ggaaatgaat tattcgccaa actatagtgc aaaaggttta
    17101 gtgaatcaaa aaaaatatct aatcggacta tttttctcaa gtttgcataa aggaacttca
    17161 tcaaatttcc tagcagattc cattgcaggc atccattcag tattagacac aaattacagt
    17221 ttatctgttg aaagtatcga tgttgttgat ttaacagaaa tcaacctgca acgctacgat
    17281 ggactgatcg ttatgagtca aagtgatgat gatcagcctt tcatcgacta tctcaaagaa
    17341 aaagaatttc ctttcgttgt tgtcaatcgt cacatcaatg atccagcggt tatcaacgtc
    17401 actgccgatg atgcggccgg tgttatgcag gcagtagatt acggtattgg atgcggacat
    17461 acgaagatcg cttatattgg cggaaagaaa aattttcgtt cgacaaaaga acgggaaaaa
    17521 ggggtattga aaagtctaaa aaaagcgagc atccctgtca atccagccta ttttttaaca
    17581 ggagattaca gcttagaaag cggcctccaa aacatggaat acctattatc actttctgac
    17641 ctgcctactc tggttttttg cggcaacgac gacatagcga ttggtgcatt gagagctgta
    17701 catttagctg gcctccgtgt tccccagaac atttctctga tcgggttcga tgattctcca
    17761 gtcgtctcct atctcaatcc gccgcttacc accgtacgta agcctttgaa agaaatgtgt
    17821 caagaaggaa caaagctttt actagatttg atcgaaggca ggacgatcga acaatctaaa
    17881 attgagctct ccaccttgtt gatccttcgt gagtcgatca attacttgta aactacaagt
    17941 aattttatat aaaaatgtta acgtgtgcat aacacagaaa ggaagtttat atgaaaaaac
    18001 tgacaaaaga attagtgaaa aaaaacgaag cacctgtaaa agttcttcag tttggtgaag
    18061 gcaattttat gcgtggattt attgattggc agattcagca gctgaataac caacaattgt
    18121 ttaaaggtaa tgttgcaatc attcaacctt tagaacaagg tcttggaaat atgatgaacc
    18181 agcaagataa tttatatacg gtcattttac aaggactcag caatggcgaa atcgttgata
    18241 cttccgagat tatcaccgta gtagaacaaa tgatcaatcc ttatgatgaa tgggatgctt
    18301 atctatctct agcagaaaat gacgacttgg cctatatcgt ctccaataca acagaggcag
    18361 gaatccaatt cgtggagact gataatttaa cagatactcc cccacagagc ctcccgggca
    18421 aactgacagc ctttttatac cgacgtttca aattaaacaa agctggcttt accatcattc
    18481 cttgcgaact gattgacaga aacggcgaac gtctaaaaga aatcatttta cgctacgcag
    18541 aaaaatggga tttagaacct gcttttgttg agtggttaga aaaagaaaat gttttctgtt
    18601 gtagtttagt tgatcgcatc gtcccaggtt atcctcgcga agatgcaggt gttttcaatc
    18661 aacggcataa ctatgaagat caattgatgg tcaaagcaga accattcatg ctttgggtga
    18721 tcgaagggcc taaagaattg gagaatcaac taccattcaa acaggctggc ttgaatgtca
    18781 tcatcacaga tgatatgact ccttatcgtg aacgtaaggt gcatttgctt aatggaccgc
    18841 atacagcgat ggtccctctt gctttgttgg cggaattgga aactgtagaa gaagtaatga
    18901 aagatccttt attctccgca tatgttgatc agttattcaa tctagaattg attcctatgc
    18961 tttctttacc taaagatgaa ttagccattt atgctgacca aatcaaagaa cgtttcttga
    19021 atccttttgc ccatcacaaa ttagaagcga tttcattaaa tagtgtttca aagttcagca
    19081 cccgtctgct tccagtgttc aagaagtata tcgaagaaca aaatcaggta ccaccgttaa
    19141 tcactgtttc actagctgcg ctacttctta tgtatcgagg cgatcaagta aagccacatg
    19201 atgatgaaaa gacgataagc gaatttactg atgcttggtc tgataatgga acagctattc
    19261 ctcgattatt gcaaaacgct gcgctttggg gagaagattt gtctcaaata ccgaatgtga
    19321 cagatacagt tcaagaaata gctgcaaaga tcgatcaaaa aggtgtccgg tcagtattac
    19381 aagaaatgaa aggaacgatg gtccatgctt gaaaccctgc aaccaacaat gaaattaaat
    19441 cgacgagaca gtgtggtcgt cgcattaacc cctattccaa aacaaacaca actgacgatt
    19501 gatcagcaaa cgatcaccac tcttgaagat atcccgcaag gtcataagat tgcattgggt
    19561 gatttgaaag ctggagacaa cgtgatcaaa tatggctatc caatcggtca tgtgacgaca
    19621 gacgtaactg ccggtcaatg gctgcacact cataatgtaa aaaccaatct ttctggtgaa
    19681 ttggattatc gatatgaaaa agatgtccat ccaagtcatt acctttttga gaaccgaaca
    19741 tttcaaggtt acttgcgaaa aaatggaaaa gtagggattc gtaatgattt gtttttagta
    19801 cctaccgttg ggtgtgtgaa tggcattgct gaactgatcg tcaaacagtt caaggaaaaa
    19861 catccagatc tgggacagtt tgaccatatt acgattttaa agcatcctta tggctgttcg
    19921 cagcttggaa aagatcatca aaatactcga gaaattttag cggacgcagt aaatcatccc
    19981 aatgccggag gagttttagt atttggatta ggttgtgaga acaatacagt tcctgaattc
    20041 aaaaaaattt taggtgaata tgatgaagaa cgagtgaaat ttctagtggc tcaagatgtt
    20101 tacgatgaga tcgaacaagg tgtggctcta ttagaagagc ttttaacagc ggcggaaaat
    20161 gaccagcgca tatcagtccc gctctctaag ttgaatgtcg gtttgaaatg cggcggttct
    20221 gatggtctat cgggaataac tgctaatcct ttacttggtg cattttctga ctacttgatt
    20281 gctcaaggag gcagcacgat cttaacagaa gtgccagaaa tgtttggcgc agaacaagta
    20341 ttgatggcac gagcggaaaa tgaagaagtt tttgactcaa tcgttgactt gatcaatgac
    20401 ttcaaacagt atttcttgtc ttacggggaa ccagtttacg aaaacccatc tcctggtaat
    20461 aaagcaggtg ggatcactac attagaagat aagtctttag gctgcacgca aaaatcagga
    20521 agctctcctg tcgttgatgt gctacaatat ggcgaaaaaa tcagaaaacc agggcttagt
    20581 ttattgcaag ctcccgggaa tgatcttgta gctgcctctg ctcttgcttc atccgattgc
    20641 cagttggtct tgtttaccac aggaagaggg actccgtttg gctcatatgt cccaacggtc
    20701 aaggtatcta cgaatacaac tctttttgaa cgcaaaggtc attggatgga ttttaatgca
    20761 ggcgtcttat tagaacaacc aatggaagta atcttagaat cgtttgttca aaaaatcatc
    20821 gctgtagcta gtggagaaga aacgaaaaat gaacaaaatg acgttcgaga aattgccatt
    20881 tttaaaaacg gagtaacact ttgattttca taaaacagta taaaaagaaa gaaggaagat
    20941 ttatgttttt atctgatgat tttttattaa aagacgattg ggcgaaaaag ctttaccatt
    21001 cctacgcaaa aaacatgccc attattgatt atcactgtca cttagatcca aaagaaattt
    21061 acgaaaacaa caatttcagc aatctgacag aagcttggtt aggaggcgat cattacaaat
    21121 ggcgcttgat gcgagcttgc ggcgtgcctg aagaaaaaat cacaggaaat gcttctgatt
    21181 ttgaaaaatt tttagcttgg tgtcaaaccg taccaaaaat tatcggaaat ccgctttaca
    21241 gttggtcaca tcttgaattg aagcgtttct tcggtattga cttgttgata aatgaagaaa
    21301 atgcagagaa aatttggaca caagcaaatg aaattttggc agctcctgat tttcgccgtc
    21361 gggaaatcgc aaaaaaatcg aatgtagaag tgatttgtac aacagatgat cccgcagacg
    21421 acttgcacta tcatcagttg cttgctcatg aagaaccaga tttgaaggtt ctaccttcat
    21481 tccgtccaga taaagcactc aatattgaaa aagaaggatt taatgcatgg gtcacactac
    21541 tggaagaagc agctgaccaa acgatcacca cctatcaaga actgatagaa gtcttagggc
    21601 agcggataga atacttccat caacatggat gtcgtgtttc cgaccacgct ttagacatct
    21661 tacgctataa agaagcggat gaaacagtat tagaagagat ttttcaaaaa gcacgagcta
    21721 acaaactatt atcttcagat gaaatcgatg cttatcgtac agaaacactg atacatttga
    21781 cccacttcta tcattctcat aattggacga tgcagctgca catccatgct tatcgtaact
    21841 gtaatacaca aatgttggaa aaattagggc ccgataccgg ctatgatgga atgaatgatc
    21901 tttctttgac tattcctctg caaaaattat tgaaccgtgc agaagaaacg gatcagttgc
    21961 caaagacgat cctttattca ttgaatccga atgactatcc tgcgatttta gctttgatgg
    22021 gctgtttcca aaaagaacag aatggaaaac tgcagttagg ttctggatgg tggtacaacg
    22081 atactcgagc tggtatgcgc gatcaattga cacaatttgc tgatggtagt gctttgggga
    22141 attttgtcgg catgctgaca gattcaagaa gtttcctgtc ctacactaga catgaatatt
    22201 tccgtcgtgt tctttgtgaa tttttaggcg aaatggtcat gcgaggagaa gcacctgaag
    22261 atgaacaact tttaggaagt ctagttcaag cgattagtta tacaaatgct aaaaattact
    22321 ttggcttttt tgcctaattg attaatagta acagtaacga atcaaaaaca ggatagtgaa
    22381 ataacggaat ccgtttatcc acgttttaga gaagaagacg gaccaaattt gctccgtctt
    22441 cttctcttgc tgttctgctt cattgcctat aaacctttat gaaagaagag ataacatgcc
    22501 tactatccat attgccggtg attctactgc ggcagaaaaa gatgaaaaca agcgtcccga
    22561 gacaggttgg ggagaaaaaa tctctgctta tttttcaccc gagatccaga tcaataacca
    22621 agcaaagaat ggacgcagca ccaaatcatt tatccaggaa ggaaggttag cccgtctagc
    22681 ttcacagttt cagccgaatg atttcttatt tgtacaattt ggacataacg accagaaaat
    22741 ccaagaagaa agaggtacgc ttcccttcgg tagctattta aaaaatctgc agatattttt
    22801 tgaatgcgca aaaaaagcga acgtccaaat ggtcttactg acatctgtga cgcgacgaga
    22861 ttacttagaa aacggaacat tgaatccaga tatacttgga gactatccaa aagcgatgcg
    22921 tgcatttgct gagaaacacc atattcctct tttagatgtg ttctcaagat cacaagaatt
    22981 gttccagacc ttctcaaaag aagagacaaa aaaattctac ctgcatctta tacctgatac
    23041 ttgtaaaaat tacccagaag gactaaaaga caatacccac tttagtccag aaggcgctga
    23101 taaagttgcc cgaataattg ttgaattgat aaaagaatcc cgtctgcctc ttgctaatta
    23161 tttacaaaaa ggagtttgag atgtttccat taaatttagg catccgtgcc cacgatttag
    23221 atgttcgaaa tcgtgaagaa atcgttcaaa aagtatcaca gcttcacttg tcccatatcc
    23281 aatttgcacc acaaaaagca tttcctgaac aacttaaatt aactgacatg acacttggga
    23341 gtgctgccta ttttggtgaa tacttccaaa aaaacaatat cgaactttcc attttaggat
    23401 gctatatcaa cctatccagc aaaaatcaag aagttcgtgc acaagcattg gcaactttca
    23461 aacagcaaat tgctctgtgc tctgcctatc aagccaagat gattgctacg gaaaccggta
    23521 gtgtctctgt cggttacaca aaagaaaatt ttactgaaga agcttatcag atcgccagaa
    23581 attctatcat tgaattagtc gctcatgcag aaaattttgg cgtaactgtt gctgttgaag
    23641 cagggatcaa tcatccaatc tataactatc agttagctaa acgtttaatc gatgaagtag
    23701 cttcaccaaa tttaaaaatc attttagatt gtgcgaattt gatgcataaa gaaaatcatg
    23761 ctgatcagga aaaagtgatc cgaggtgcct tggacaattt acatggttat attacagcgc
    23821 ttcatctcaa agactatatc atggaaaatg gaaagatccg catggtacct gttggcaagg
    23881 gctgtttaga tttccgcccg gtactgcatt atatcaaata tgagcgtcct ctaatgtacg
    23941 ccactcttga agctactcct gagatttatg ttcctgaagc aatagaacac ttgcagttta
    24001 tttaccaaga ttgttaagga gaagattatg gaggaacgaa tacagaaaag ttatcaaaaa
    24061 tatcatgcaa atgcttttca gacattgctg catctttatc agggaaatta ttggcgtttt
    24121 gccatgtcag gactcttttt tattatcaaa catcttccat cttggttaat gccgatcgct
    24181 attgccaatg taatcaatgc agcttcatcg aaagattctt ctcagttgca ggccatttat
    24241 ttcaacgctt ttttgatggc ttgtctgatt ggtcaaaata tattgacgaa ttattttcat
    24301 gtaaaatacc atagcacttc gatccgtcaa gtagaagctg gactaagagc gacccttatc
    24361 aagaaaatcc aagaactatc tattccttat caaaaagaat tgcaatctgg acgaatccag
    24421 tcaaagatca tccgtgatgt agaagctatc caaacgttgt cctctcaagt atttgtcagc
    24481 ggattaaata tcgctgtcaa tttattcgta gctttaggta tcacgcttta taaaagtcct
    24541 gttgttttca tgtttttctt attgactgtt cctctcgccg cattcgttac tctctttttc
    24601 cgtaaaagga tcagacagtc caactcagac ttcaggcaag aaatggaaga gacttctgca
    24661 aaagtgatcg aagtgatcga attagcaccg attgctcgag ctcatgggtt agaaaaacac
    24721 gaaacaactc gcttaaataa gcattttact caaatctatg aaaaaggatt ccacttagat
    24781 atcctgcaat ctgttttcgg atcagtcagc tgggctagtt ttcagatatt tcagctgatt
    24841 tgtttgattt tcactgggat attagcttta caagggcgca tccaacccgg cgatgtcgtg
    24901 atgtatcaga cgtatttcac gacgatcgtc aattccgttt ctggaatgat cacgctgatt
    24961 cctacgattt caaaaggcat ggaatctatc acttctattg gcgaactgtt gattgctggc
    25021 gatgtagaaa cttatcacgg taagaaaaaa atccaacatt tggatggaaa ttttcgtttt
    25081 gaggatgttt cttttcttta tccggactca ctcaaaccga ttatcgatca tttttctcta
    25141 gaggtgaaag ctggagaaac aattgctttt gttgggccat ctggctctgg aaaatctaca
    25201 ctccttaact tattgattgg atttatccag ccgacttcag gaaaaatttt tctagatgat
    25261 cagcctttgg atgaactgga tatgcgaagt gtgcgaaatt atttagccgt tgttcctcaa
    25321 accactttgt tgttctccgc ttcgatcaaa gagaacatca cttatggctt gaaaaacgta
    25381 tcaaaagaac gtttagatga agtcatcgaa gctgcgcaac tttcttcact gattgaccag
    25441 cttcctgatg gtctggatac cttagtaggc gaacatggca acaagctgtc tggtggccaa
    25501 aagcaacgta tctccattgc acgagcgttg atacgtcagc caaaaatcat tttgctagat
    25561 gaagcaacct cagctttaga taaccagtca gagaaaaaaa tccagcaagc cctgaattac
    25621 ctgacagaaa cacccactac ttttattgtg gctcatcggc tttcaacgat caaagaggca
    25681 gataaaatcg ttgtgatcga tgaaggaaaa atcgttgaaa taggtactta cgaaaaactg
    25741 ttagctcaaa aaggctattt ctaccgcttg aaaaatgaat gacaaaaaat aggagctatg
    25801 acaagacttt tgtcgtagct cctatttctg aataaacggt gttctcctgc caactcctcg
    25861 gtcacaagtc acaatagtca tcaaacatga gaagctgttt tttgaaattg ttccttgtaa
    25921 ctcagagtta aacggtaggc tcacgacctc ttggtaaatg gtgttcaaga gacagcctat
    25981 cggcaataag aagcaatttt gtcatcgctc aaggccgaac gtctctttca caccctctgt
    26041 tgtttcataa aatagtttta ttcgctgtaa aggtcgcgaa ctggtgtcat gatgatacgg
    26101 ttcaagtcat tgatgattgt actgaagcct tgctcttttt gcatcaagtc attgattact
    26161 tcttctgatt ggattttcac agccatttct tgtgctttca ttgcatcttc gtcgctgaac
    26221 tcttgtccac tcatttgttt ttcttgtaat tcgatttgca tcgcttggaa gtctttgaac
    26281 agtttgtgtg cttcttcgtt tgcttgtact ttctcgtacg cttctttcaa cgctttgaat
    26341 tctggtaatt cacggatctc acgttcgatt tgattcgcgc tatcgtagat gtttgacatg
    26401 ttatgccctc ttttctttta gtagttactc tctattgtaa catggggtta ttcgttttca
    26461 aaggggctac tctccttgat atttccgcca gaggtcttta gccgcttcac caattccctg
    26521 aacgccttct ttcaccatat cgccgaagtt tttcagccct tcttttgctt gttcaccata
    26581 ttgattcaag ttatcttgcc aatttccaga ctctccatta gaatttcctg tgtttccaac
    26641 ttgatctgca gctaccactt gtcctcctgt ggcataggca tctgctacac taaatcctgt
    26701 ttttgaagta tacggaagga tgccttctgc cgctgatttg aagactttcc cgacaacatt
    26761 tccacttgtc ccttccaaat agtgcagctt gctggattct tcgtaaccca tccatgtcga
    26821 aatcactacg tctggcgtgt aaccgatcat ccattggtca tttgcttttg tggcatcgaa
    26881 attagtttct gtggctcctg ttttccctgc tatcgtataa cctgcaggat tcgcagcagc
    26941 cgctgttcca tttgaaaatg taccaagaag catgctggtc atttcatcgg ctgtttcctt
    27001 tgatatgacc tgttttggtt ttttgtttgt gttatcgacg atcaccgctc cagtcgaatc
    27061 aacgattttc gtgataagat gcggcgtata catctgacca tcattggcaa atgcactgta
    27121 agcacccgcc atgatcaatg gagatactcc tttttccagt ccaccaaggg ctaagccata
    27181 atacttatca gattttgcta aaggcaggcc gaattcttct gctttatcat atcctttttg
    27241 taaaccgatc tcatgcaaaa gccatacagt aggcaaattc aaactttgtg caacagcttg
    27301 atacatcggt acttctcctt ggtatgtccc gtcaaaatta tgcgcatcgt aataactttg
    27361 cggttcgtct ttcaagatac tggaaggctt gtatccagct tccagtgctg gtgtatatac
    27421 gcttaatggt ttgatcgttg atcctggtga acgacgcatc tgtgtagcaa agctgaatcc
    27481 tctaaagaca tgatctcctc ttcgtcctac tagtgcttgt acaccacctg tattcggatc
    27541 taaagctact gaagcagatt ggaccatggc accatctgaa gcatttgctg ggaataatgc
    27601 actgttttga taagtagctt ctaattgctt ttgataatcc tgatctaaag ctgtatagat
    27661 tttatagcct ttattcatga catcttcttc atcaagacca tactcgttaa ctgcttcatc
    27721 gatcactgca tcaaaataat aaggataacg ataaccagaa tctgaattat cgtatgtgtc
    27781 attaagatac gcgctgatat ctgtctggct ttctgcttgt tcttgttctt ttgtgatttt
    27841 tccgttttct tccattacac ttagtactgt gtttttccga tcattcgcat tttttgggtg
    27901 atcgatcgga ttataaatac caggaccttt cagcattcct gccaaagtag cagcctcaga
    27961 cagcgtaaca ttcgttgcat ctactccaaa atactttctg gaagcgtctt ggacacccca
    28021 taccccgttg ccaaaatagg cattgttaag atacatggtc aagatttctt ctttgctgta
    28081 cttcttttcg atctcgattg ccaaaaataa ttccttcgct tttcgatcaa acgtttggtc
    28141 taatgtcaga tacgcatttt tggcaagctg ctgagtgatc gtacttcctc cgccccctga
    28201 tgttccgcca gacaagacca ttcggactgc tgcacgggca atccctttga tatcaaaccc
    28261 gtgatgctcg taaaaattcc tatcttctgt cgagattact gcatcttgga tatagggaga
    28321 aatcgcgttt aattctacat atgttccttt ttgggcgtac agtgtgccag cttcttcgtt
    28381 tttcttatca taaacgactg tcgattggct taatcctgat tttaacgttt cgacatttgc
    28441 ttgttttgct aaaataaaga ggtagatact tgtcactaag acacagatca aaccaatcag
    28501 caaaatcaat ttgttcacat gatatttttt ccagatgcgc tttcgccatc gatggaattg
    28561 tccgagatat ggtctgatcc aacgccaaaa actgatcaaa gcagctttta tcttttctaa
    28621 aatgctttga aaatccattt gcttcttctc ctgtctattt gattcaatcg tcttatttta
    28681 ccatagtgaa agagtgtttt cttcctgctt aagttgtagt tcaatatgtt tttttacgtt
    28741 agtgcaagta gagtaacata agaatgaaca gaaaaatgta agttttttct taaatatgtt
    28801 ttaaaaatgg tacaattagt ctgcgattgc actgaaagga gtacacttgt gaaaatcacg
    28861 atcactttac ctatgaacca tcctgaaaca acaattcgcg acttgcttga aaaggaatgg
    28921 ttagttccta gaaaggttcg acactttttg cgtatacgta aaaacgtttg gatcaatcaa
    28981 caacctgctt tgttccatca tgaagtaaag ggcaatgacc agatcacatt gttattcgaa
    29041 gaaacagatt ataattatca agaagttcaa ttaggagatg cgaagcacat ccgtgtttta
    29101 tatgaagatg agcatttgat tatagtggat aagcctgcag gaatgaagac tcatccaaat
    29161 gaaccgacag aaaacagtac cttactcaat catttagctg cttatctcga cactaaacag
    29221 caacgacctt acgttgtcca ccgcttggac aaagaaacaa gcggtgccgt tttatttgca
    29281 aaaaatccat ttgtcttgcc gatacttgga agaatgttgg aacaaaaaat gatctatcgg
    29341 agatatcaag ccatcgtatg gggagaaatt gccaaagata tgaccatcac caataaaatt
    29401 ggacgagatc gccatgatcg gagaaaaagg gtcgtagatg ataaaaatgg tcagagcgcc
    29461 ttgacacatg tcactgtcaa caaagtactt tctgaacaaa cacaagtcta ttgtgttttg
    29521 gaaaccggac gtacacacca gatcagagtt catttagctc ataagggaca tccgatcgtt
    29581 ggagaccctc tctaccaaaa tagaacagct gaacgactga tgctccatgc attagaactg
    29641 cacatgatcc atccatttac tcaagaaaaa atagtcggta aagctttacc tggattatgg
    29701 gaatagaaat aaaaaagaac agagtcttat cagcagataa tgataagact ctgttctttt
    29761 tgtgtaattt gtctgcttac ttttgatgtt cgtgttctgc taacagcaaa ctaccgataa
    29821 tcccactttc attcggcagt ccccaacgaa cgatatattc acttacttga ggtgtttcca
    29881 tataaccacc catcaattca acaaattgct gacggatttt ttgaaggaga tgatcctgat
    29941 tcattacccc accgcctaaa ataatctttt caggtgctaa cgtcaacgta tagttgatca
    30001 gtgcttgagc aatataataa gcctgaatag cccaaacagg atgatcttgc ggcagatctt
    30061 gccctttgat ccctgtgcgt gcctcaatag acggtcctgc tgctaatcct tctaaacaat
    30121 ctttatgata aggacaagta ccttcataat ggtcatctgg atggcgtttc acccaaatat
    30181 gtcccatttc aggatgtgcg atccctgaaa aaatttcttc attgatcacg acacctgcac
    30241 cgattcctgt tcccacggta aggtaaatac aactattttt tccttgtgct gctccttgct
    30301 tcaattcccc atatgcagca gcattgacat ccgttgtcca agcagcagga atattgtagc
    30361 gttccttgat tgtgccaaga aaatcgaatt gtgcccaccc ttttttggga gttgccaaaa
    30421 cgtatccgta attatctttt gttttgtcga taccaatcgg gccgaatgag ccaatcccga
    30481 ttcccttcaa ttcataacga tcaaaaaatt caaatacctg atccaatgtt tcttctggtg
    30541 ttgtggtagg gatacttaat ttttctaaaa tttctccacc atctgaaacc gcacacacaa
    30601 attttgttcc gcctgcttct attccgccat acattcgttt tcctcctcga atccgattgt
    30661 ccgaatctca taaggttgga ttattgggac aaccgcttgc ttcgttggtt cttcaagcag
    30721 attcaatatg acagtttttc cattgtcttt agttatttcc aatttttcta aatgactaga
    30781 catattgaaa cctcttacta ctactttatc actaaacttg ctgcgtttca aagctgtaat
    30841 tgcaaacgtt tcacttttta tcgttaaata ttgttgtttt gaaatcaatg ttccttcatg
    30901 atgtttgatt tgttgagtgg aaaaaggaat ctgtgctgcg tatgcatgca aataagtaga
    30961 gaatttttct tctggtccat gtagttcaat gctgtaattg aaccgatgct cacctagaca
    31021 ctgtgcttct ggtgttggaa aatatcccca atcgcctagt tctcccacac tgcgaagtag
    31081 cgtcactgcg atttgtccgt cttctgttac ttcatattca ttcaaaccaa agtttccgac
    31141 tgttacaccg tactcttcat catgaatatt gacaaatgct tgctgatgtt gcggattcgt
    31201 ggggttttcc caacttttag acacatggtt tgggcgcttc accacttcaa aaatactatc
    31261 tgcttcgtga tgttccacat gtaactttgt aggaaacaag acacgtaagc gatgatcttt
    31321 catctgattg tcgagagtcg tttcaaagtc gattttttta ctatcttttc tgattgtcat
    31381 gattgttttt atttgaagga ttcgtttttc tttggatcgt tctgcttttc gataacgaaa
    31441 ttccacaacc atctgctgtt ctttttctaa acgctcgtct gcagaaacag ggatttccat
    31501 ttcctgtaga atacttattt ttgctatttc cggtgtatct actaatactt ttacttcaga
    31561 gttttctttg ttactggata ggattggctg atcacagaaa ggttgtttaa agatatactc
    31621 atttcctata tcgccgatat cttcaaaaat atgcagatta ttcaactttc gtttgttttt
    31681 gcgatcttcc attgtaatgg taccattttt ttcaatcgtc aaatgtagag ggccgttttc
    31741 gatgattcgt ccactctgat gaatcattgt ttccttttct tctgctttcg cttccccttc
    31801 tacaagcgcg aatgtttccc aagaaaatgc tggcatgttt tctaatggta aagtcacttt
    31861 gatcattctt gccatatatg gcacacggaa acggtctttc ggcaaatcat aaccaaattg
    31921 gacagtttct tcagataaaa tagctggtat agtggcccca ctttttgttt ctacatgata
    31981 cttacgttta ggcaaatttt ctaactcttg atatagttgt tcaggtattc cttcagcgaa
    32041 tctttttctt tctaattcga tggttatttc tgcttcacca gttttatcca ttcctgcagt
    32101 atttacaatg acaaatggaa agctgtcttt tgggaatccg gtcgtatcga ttgctgcggt
    32161 cagctgttct aaggaatctt gtgcaagata ctttccaact tcatctgctt tttcaaaacg
    32221 aggtatcatt tcccgatgga cagaatcgac tgaacaaccg caaatactgt cgtgaggatg
    32281 attttgcatt aatgtcttcc aagcataatc taattgatca tggggatagt ttccactaac
    32341 ttcataagcc atcgtcgcaa gtggttctgt aatattttct agctgtcgct ggaccttggt
    32401 attccattgt tttaagtaaa cccgagcaga tgctgtattg gctaaagtat accagccatc
    32461 cgtttcttga cttgtcaatt ctccttctac tgagcctaag tcttctggca catctttttg
    32521 aactgcttcc agatagtcag taaaattaga atgaataaac tcgtaatctg gaaacagttc
    32581 atttgcgaga tggattgctt ttgatatatc tttttgtacc ggttgatgat caacaccatt
    32641 catcatcaat aagtggttcg tagaggcata ttgttctgca tccgctaatt tttgcttcca
    32701 aaaggcaaga gctgcttctt tttctactgg aatctcattc ccgttgctat accaattggc
    32761 aaatagcaga ccaaagattg ctgtttgatc aggtcctttc caccacatct ctgagtattg
    32821 ggaagaatag ttttctgctt ccaaaacttg attatcaaag ccaattggtt ttacaccacg
    32881 gccaaacgct gctgctgaaa taccagcttg tttcattaat tgaggcgtct gtcccatatt
    32941 tccaaatgta tcgggaaaat agcctaacat gacaggggtt ccccatttac ggctttcttc
    33001 catgccaatc agcatatttc tcacgttcga ttccgagctg ataagaaaat catcttgcaa
    33061 gatataaaat ggtccaattc tcaattttcc ttcattgatt gcttgttgga ttgcctgtct
    33121 tttttctggc cttacttgaa gatagtcatc taaaataatc gtttgcccat ccaaatgaaa
    33181 actgttgaag gacggatcaa cttcaaatag ctctagtaga tcgtctatca attcaatcag
    33241 tcgcatgtga tgctgttcgt aagccatgta ccattcacga tcccagtggc tatgagaaat
    33301 gatatatact ttctttttca tttacgatac ctcctacttt tctactctaa tatcaaagta
    33361 atccatgact aattcgcaaa acatcatatt tgcccaagaa aaccattctc tcgtataatt
    33421 ttcaggattg ttcacatcga atccttcgtg cataaggtgt gttcctgcgt cagttgctac
    33481 aagtaaattc aatatccgct ctttttcaga tttgtctgac gttgtcattc cttccatagc
    33541 taatgcaatc ggccaaacgt atttttctgg cgtatgggag gatccaattc cttttgcgta
    33601 ctttccttca tagaaatatg gattttcttt actcaacaat gttcttcttg tttgcagata
    33661 atcttcctct tgttcagaac aatatcccaa gtaaggtgcg gcgatcagat tgggcacatt
    33721 actgtcatcc atgactgtgg cgtttcccat tccatctact tcatatgcat aaatcgtttg
    33781 ccctttttga ttaaccgttc gtccgtgatt ctgaatcccc tcttggatct ctttcttcaa
    33841 tttctgtgtt tgctgtacaa tttctttatc atcgagtatc gtttgaaaaa tttcttccac
    33901 ataacctaac acgaccaccg caaacatatt ggatggtacc agatatccat aacggcaagt
    33961 atcatcgcta ggacggaaac cagaccatgt cattcctgta aaagctgttt ttgcacctcg
    34021 cccgtcattg atcagcgtat cttcttttct tgtcgtgtct cgtacaaatg tataaggaga
    34081 gtgttcatga tcttgctctg ttttgaacac gtccaagatt tttttgatac cttcaataaa
    34141 agattgattg aattgatcag tttttcctgt atttttgtaa agaagatagg ccaactgtat
    34201 tgggtagcat aaagaatcaa tttcatattt tctttcccag atccaatcgt tcatttttgt
    34261 atgatctgtt tggtggccag caccgttagc ttcttcgttg aaggcattcg catatggatc
    34321 gatattgata taaaaaaatt gctttttgac taacccgctg atcatgtcag ctaattcctc
    34381 atcttctttt gcaatcacta aataaggacg aacttgtgca gtagagtctc ttaaccacat
    34441 cgctggaatg tctcccgtca ataaaaaggt ggttccgtca ttttgctttt tgactgttgt
    34501 caacagagta ttggcaaatg ctgctgtaaa attctttgcc cagtccgcat ggatatcccc
    34561 acatttttgt gtgatatctt ccataaattt ctgcaccgat tttggtatat ctttataagc
    34621 cactaataaa accttctttc tatttgatat atctttaaag attatacttc atacagccaa
    34681 ttatgtctac gctttcaaaa aatatctttt tatttacttt ttcatccatt atggtattat
    34741 ttgaatatga tatatcatta agaggtgttt atatgaatca accattgtac cagacaatat
    34801 ttaatgattt gcaaacggct attttaactg gtgaattacc tgtagacagc caactaccaa
    34861 ctgaaaaaga actttcacgt acctataaag taagcagaat cacttccaaa cgtgcattga
    34921 ctgaattaga gcaattagga cttatttatc gcgttcgcgg gaaaggcagt ttcgttaaat
    34981 ccgcttctcc ggaacagatt cttgcttctc ctacaaaaac acgacggatt ctgtttcttc
    35041 ttccatatgt cgctgatttg tctgttggtg attttagcaa gggattgaac cctgtgatgc
    35101 aagataaaca gattgatgtc atgatgacga cgcttgactt tctacaaaat aaaacagcaa
    35161 aagagctaat caatgaattt gacggattga tttattatgc tcttgataca gaacaacatc
    35221 ttgacttact ttttgagctt tcattgaaag aattccctgt cgtcatatta gataaaaaaa
    35281 tctatgagtt accttttcct accgttcttt ccgataattt ccaaggcggt gcgcttgctg
    35341 cctcttattt gatcgaacag ggacattcaa aaatcgctta tttgtttggt acgcagactc
    35401 atccacaatc cgttcgacag cgttaccttg gttaccttga agcattggac aaagctggtt
    35461 tgactttcca cacttcactg gatgacaaaa gcgcgacatt agatgaattg ctttcttata
    35521 tcactaagta tgaagtaact gcttttgttt gtgaaaacga tgttgtcgct atccagacca
    35581 tgaatctctt gagacagcat ggttatcata tccctgaaga tttttcaatt atcggatttg
    35641 atgatatcca agcagcagct cttgttgacc cgccactgac aaccatcgca caagattttg
    35701 aacagttagg taagcttgcg ggagatgctt tggtcacttg gttagagaca aaagatcgac
    35761 catccgatag taaatttcca gtttcattca tcaaaagaca atcaacaaag gagaaataaa
    35821 atgaatatcg gtcaaataga tactagacat gcaacagcga atcagccaaa tttctctaat
    35881 gggaactgcc agccttatac tggcgttcct tttgggatga attattttgc accgcaaact
    35941 acggatcaaa acggcagctg gtggtttcat cctgatgacc gcgtttttca aggctaccgt
    36001 cttacccatc aaccaagtcc ttggatgggt gatttcagtc atatgctgtt tacgccgatc
    36061 aatggaaaac tacaggagaa cacccttttc catgctcaaa gttcttaccg cccagaagaa
    36121 agtatatttt gcccgactca tctgtcgatc tgtcaattac gttatggcat ctgttctaca
    36181 ttgataccta gcatgtatgg cggaatctta tctattgatt acagcaaaaa tgacagcggt
    36241 ttacttttat cctttccggg acgccatcag ctctttgtta tagatcctta cacagtggaa
    36301 ggaaaaatca cacattttgc tggttcagaa gatcctgatt tttcttttta ttttatattg
    36361 agatttgaat atcctttaac aattgatgag ttagctgttt ccaacaaaaa tagcgactcg
    36421 atcccgttgt attttgaaca gacaaaaaaa caaactatcc gatttgggac atcttttatc
    36481 agctcggaac aagcagctta taacctggaa ctagaacaaa accaaagcaa agagacttac
    36541 cttgctcaca gtcaagaaca atggcagtcc tattttgatc gtatacagct cacacaccat
    36601 gatcaacaac aattgcggac gttttatcat aatttatatc gggtgttttt atttccacaa
    36661 acattttatg aaattgatcc tagtgggcaa aaaatccact atgatacgac tagtcgatct
    36721 ataaaacctg gtgttctcta tacaaataat gggttttggg atacgtataa aacggtttat
    36781 cctctttatt ctttgattgc tgtagaaaaa tacgaagaaa tgctggaagg ttttttgaac
    36841 agctatagag aaagtggcta tttgccaaaa tggctgtctc ctgatgaacg tggacttatg
    36901 cctgggacat tgatcgatgc ggtcattgca gatgctgctg taaaagatat ccgacgagac
    36961 ttgatgcctg aatttctaac ggcaatggaa aaaggtgcta cggttcaaag caaacatcca
    37021 aattatggac gccaaggaac agaagattac ttgacatatg gctatgttcc taatcactac
    37081 cacgaatcag tcaatcacac attagactat gcttatagcg atttttgtat tagccaagtt
    37141 gccaaggtac tagaagaaga ggaaatgacg aagaaatatc agcagcaatc attgaactat
    37201 caaaatatct ttgactatga gtcaggattt atgcgttcaa aagataaaga tggcaagttc
    37261 agagaaccat tttcagctaa tcgttgggga caagattatg cagaaggaag tgcttggcaa
    37321 agcagctttg ctgtttatca cgatttttca ggactgatcg gaaaatatgg tggcagtgag
    37381 agatataaag aaaaactcat tgagctgtgc aatcagcccc caacgtttga cccaggagga
    37441 tatggttttg agatccacga aatgagtgag atggccgcga tagaatttgg acaattagct
    37501 atttcaaacc agccaagttt tcactatcct tacttgttca gttatatagg acaacctgaa
    37561 atggcacagc cactgcttaa acagttgatg actcagacct tcgacgattc tccaatgggt
    37621 taccctggag atgaggacaa tggaagtatg gccgcttggt atatcttcaa tagtctggga
    37681 ttttatcctg tcacgcctgg aaccggtgaa tatgttatcg gtatgccatt aattgacaag
    37741 gctgttttgc ttttgtcaaa tggaaaggaa ttgacgattg aagcaacgcc taatcggccg
    37801 cagcaacaat ttatccataa aatcaaacgg atggacaaag aatatacgaa attatatttt
    37861 acccatcaag atttgctgaa aggcggcacg atctcttacc aattagggat catccctcac
    37921 cctaagaaat atcaagcaaa agatttgcct ttttccttat caaactataa ttaacaagag
    37981 gttgtgaaaa agctgtcctg catcaagtaa taagaacagc caagcaaaaa tagatcctca
    38041 tatttttcgt ttggttggtc ttattaccgc agatgcaagc ttttgaacac cgtttattga
    38101 gaggttgtga aatcagcgtt ctgacctgag tattagagag acaaatggca aaatagttcc
    38161 tcatattttg ccattttttg agctaatacc gagggtcagc tgattgaaca ccgtttagtg
    38221 gagaggtcgt gaaaaagctg tttagtttcg agtattaaga aaaattttgt gaaaatggct
    38281 ttccacattt ttgcataaat ttggcttaat accgagaaac tggcttttga actccgttta
    38341 tcgagaggtc atgaaaaagc tgccttgcct caagtaataa gaacagccca aaattagatt
    38401 tctagacaat tttttataag ttatttcatt acattggctt tttcttttat gattctccac
    38461 tgttttctcg gtactcttta ggggatctgc cgacgatttt cttgaataat ttagagaaat
    38521 acgtggtgtt gttgtagcca atctcacttg ctatctcatt gatgttttga ttactgtgca
    38581 aaagcagttg tttcgctttt tccatacgta aatggttcaa ataagctgaa aaactttttt
    38641 tcgtttcttt tttgaacagc tgtcctagat acatgacatt taaatgcagg ttttctgaca
    38701 cttctttgag tgtaagtggt tcttgataat gctggtgcag gattacgatt actttttcca
    38761 cattgtcact gtactttttc tgtctctgat gctttttgat gaatgacaga agtagctgct
    38821 gaagttcttg caccgttttt gcctgatgga ttttttcgat tccttgtaaa tattcctcat
    38881 cttccagatc aatcaattcc cgttgaatct ccataaacag taaaaaactg gaatatcgta
    38941 tatcttccgg catcatggct gctaactgaa actgttcaaa aaaatcagtg atcatttttt
    39001 gagcgacttc caattgttta ttttgcagca cgcgtctgaa acttgaaaaa tcgatggttt
    39061 gatcttttgt ttctgcttgt actgcgtaaa aaacatgctc gtctttatct ccataaaatt
    39121 gatgcaactg tagattgtct ttcgcttgtt ggaatgtttc agggattttg tccaaagaat
    39181 ctgtctcttc cccgatactg atcagccatt cctgatcagg aaagttttct tgaacaaaac
    39241 aacagaagcc atcaacttca tctgcctcca acaacaacgt gatcaataca cggtctccgt
    39301 aatttcgttg atagtaaaag atttgttgcc gttcttgcaa ccatctattg ataagagtat
    39361 catgagttct tgccagttga atcaatacta tcctatgctg cttctcactt atttgtccta
    39421 ttatttcttc ttcacttatt tcatccaatt cttcattcaa ccattgactg aataacagtt
    39481 cttgatagat ttcttgttga tttttttgtt cattttgctg atctaaccgt gttttgattt
    39541 tcttgaggct ttcaaccaat tcgaacttat tcacgggttt catcaaataa ttcacggcgc
    39601 ctaattgcat acctcctttc aaataatcga attcttggta tcctgataaa atcataaatt
    39661 caaaattatg acgttctttt tgagccgctt caataaattc cagtccattt atttctggca
    39721 ttgtcacatc cgttactact aaatcaatct gtcgctgttc aagtacagct agtccttctt
    39781 tggcattctc tgctgttgct actatttgaa agcctaaact ttgccaatca attatctttt
    39841 ttaacccatt caaaatcatg tattcatcat ctaccaataa cacttgatac acgctcatcc
    39901 ctccttgaat gtaatagaaa cggtcagtcc acctgtctca ttattctcaa gcgacatata
    39961 ataactgctg ccgaagctgg cacgtaaacg ttcattcacg ttttgcagac cgatagaacc
    40021 gtgaagttcc actttaggat gagacagttt ttcttcaatc tgttttagcc gtttttcagt
    40081 catccctttt ccattatctt tgatgatgat ccttacccgt ttgccttcct gcaagacttt
    40141 gacacttagc gcattatcga atcgagtaaa atcaataccg tgtttaaaat aattttcaac
    40201 taatggctgg atcacaaatt taggtacttc gatcttttcc aaatcaggat cgatcataaa
    40261 atgataggct actcgattag gataacgcat ttgatacaaa tagacatatt tttcgcaaaa
    40321 gtccagttct tcttttaaag tgatcgtttt ctcttgattc gtattgtttc gaagcaaagc
    40381 ggaaaacgca tacacaacat ctgctaattc ttcacttcct tcgctgattg catacattcg
    40441 gatatattct aatgtattat ataaaaagtg tggattgatc tgtgcttgaa gcgcccgcat
    40501 atgtgcgtct tgctgtttga tttctaattt gtagatgtct tctacaaact gattgatgct
    40561 atccaacatt tcgttgatac cgattgaaag ttccttcagt tcatattccg tgtttgttat
    40621 gtcgatccgc gtctctaaat tccctgctgc tgtttgatcc atggcctgca tgacgataga
    40681 tacttgctgt gaatatcgtt tgaatgtttt ataaagaaag ataagcagta tattgtctaa
    40741 aataatgata ccaatgatca gcggggcaag attttttccc gtttcgattt ttacactttt
    40801 tttatctagt acagctaata tacgataatc atcagacagt tcttggtgtt gaacaaaatt
    40861 gtttttttcc agatcgtcaa tcggcaattg tgaatttttc ttcagactct ctgtgatgat
    40921 catttcttgt ctttcaaacg tttctttagc tattttatta tcatggaatg tgtatagtcg
    40981 atttgtcgtt ccagaaatca tgtataaaga gagtccattg aatgacgtta gattttctaa
    41041 aatcatatct agttctttct tttgaaaacc aataaaaata cttcctgact cagctcctcc
    41101 ttgtgtgata ggcaacttga tataaaaggc gtctagtaat tttggtgtcc ccttttttat
    41161 ttccccacct ttgttttctc tagaagattc ataatactcc ggtagttgat tcaacacgat
    41221 atatatcgca cttagttctt cataatttgc gtagagatct ttgatttgat ttgggaaaga
    41281 aactaattca tcggtactgt tttgctgttc gtatacatac atcagatact gatctatggg
    41341 ttttgttaag taggtcgtca cattttcgat cttttcggaa ttccctacaa gctggttttt
    41401 gatgatccta ctcaaggttg ttttatcatt cagcattctg cttgtgcttt gaacggcatc
    41461 acttgtcatg ttttctgcct gtttttgatt ttgttcccaa gtatggatac taaaaataac
    41521 ggtagcagtc atcgttacac cgatcatgat aaccgcgtat ttccgcaaca gacgatttag
    41581 taaggttcct tttgaaaata gaatccgaaa cttattcata actttccaac tgtttatcta
    41641 attcttcacg ccaatgtgtt gtcatcgtac cattccaaac cgtcaaaaga ccaatgacac
    41701 caaacaggat caatcctttg aattgccaag tcacgcctaa aattataccg ctaccaataa
    41761 ttatttttag aaaagacgaa aagctggaaa aaaccgaaat aaaacttagc tttagcagat
    41821 taggaacaga gatcgtatat tcactatcta aaatcatact gtattgataa gtagcaaata
    41881 ggcagagcaa ggcaaaaagt aaaataaaat caatagctaa aaaaatgagc cctttgattt
    41941 gaacagataa atataaattg taactcaata aagcagtacc agataaaaat aaactaaata
    42001 gcagattgcc tcttaaaaaa tttcttttat atatattcca gcctcttttt attgtgattt
    42061 ctttatactc gaatccgtac aaataaaata gttcattgac tgttttccat gccgcaccta
    42121 atccaaagat gatcccgccg gcaaatgtat atatccagaa atacaaggtt agttttataa
    42181 tgacccagat ccggataaat aactcttcca aaaccttccc taacatatct tctcctccaa
    42241 acattaagtt tatactttct cattatacaa aaaaaggttg ggcaatcagc accttgacct
    42301 gattattaga gaaacaaacg gaaaaatagt tcctcatatt ttgtcgtttt gtgagcgaat
    42361 accgagggtt agctgattga acaccgttta ccaagagttt gtgaaatagc cgcttagttt
    42421 cgagtagtaa gaaaaatttt gtgaatatgg ctttccacat ttttacatat atttagctta
    42481 ataccgagaa actggctttt gaacaccgtt tattcggaac aagaggttgt gacacgtctt
    42541 ttgtcacaac ccctttgtct ttattcatta ttattcttgt cggaactcat catattgttt
    42601 ttgcatttct ttcaatacct tatcatagcc agccttgtcc aaagcgtctt tcaatttcgg
    42661 taatgtttca tctggatcaa cagtccctgt attcaatcca tctaaatatt gattcatgac
    42721 attagaaata ttacttaatt ctgttttgac actgtcagtg ttgaagctga atcctaaaat
    42781 cggtgaagtt tctgcatcag caatcgattg atcacgtttg gcaatcatgt catccgtaat
    42841 agactcttgt gtatatagaa tcttgttgtt tcctgtattc caagcagaca tatgtgtatt
    42901 tggctgataa ccatctagca atttgatttt atcatctgaa ccatcgactt tttcccatgc
    42961 ttctccctcg atcccccaaa caagcccatt caataattct ggatcactgt taagcagccc
    43021 tagaagttct actgattttt ctttattttt tgaagtattt gatacgacaa aatttgccat
    43081 ttgtgcttga gctgtagatt ttagtggaac agtaattgct tttgagacaa gttcttgttt
    43141 tgctgcattt gtcaaaattg tatcgccata atcatacggt ccttgtgttt ctccacgcat
    43201 tagccaagta tttccttcta gtggataatc cttattgctc gttgcagcgt cacttggaat
    43261 gagtccttgt ttgtaccagc tatgcattgt acgtaacagt ccgatatacg tttcattatc
    43321 gtattggttg atgattttcg aatcatctcc atccagatca atagcaaatg gtaacgtatt
    43381 ccctaaagga taatcaaagt tcccttggac tttgaagcct tgtccaatgg caaaagctgc
    43441 cgtgtttggt tctttttcat ggaattcctt caagactttt tctgcatcag cgtaagattg
    43501 gattccatca attgaaagat cgtatttatc tagtaaagct ttgttaaaag taagtacttg
    43561 ttgagcaaag acatttccat tgactgggaa agcatataat tttccattga ccagatttcc
    43621 tttaatatat gcttcatcta aatcattata agctttttca gcgtacttag gcgctaattc
    43681 agtcaaatca gcaaaggctc ctttttgggc attggaaaca tagttgttcg caaaggcgat
    43741 atcataattt tccccggaag aaatgatgac gttcattttc ttttcgtaat cgccccagcc
    43801 aatgtaattg atattgactt ttacaccgat ctctttttcg attcgtttgt ttgctacttc
    43861 catcaattga tcgaaattat ctggtttatc tccgatttga tacatctgca aagtgtccga
    43921 attgctagct tctgcctggt ctttagaacc agaacctccg catgctgcta atgttcccaa
    43981 caacaacgct gaaacacctg taaaggctag tttcttccat aacttcattt ttcttcctcc
    44041 taattttatg atttatattt ttgtttcttt attcttttac tccgccgatt gttagacctt
    44101 tgacaaaatg cttctggaaa aatggatagc tgatcgcaat aggcaacgtc gagatgacta
    44161 cgatcgccat tctggcagat tctcctggaa ctgaggctaa tccgcctgtc aattggcttc
    44221 ctgctcctga attttgtgtc agatattgaa tattactttg gattttcatc aaaagatact
    44281 gtagtggaac tagcttatca tcttggatgt atagtaaagc attgaaccag tcattccagt
    44341 aacccaatgc ggcaaataaa ctgattgtcg caatacctgg aacagctaac ggtaaaacga
    44401 tctgaacaaa tattcgcagt tcgctagctc catcgatccg tgccgattca ataatcgaat
    44461 cagagaccga acgtttaaag aatgtgcgca tcacaataat attgaaggga ctgacagcca
    44521 ttggcaagat caatgcccaa atcgtatctt ttaactgaag aagatttgtc ataacaagat
    44581 aattggccac catccctggt gagaacaaca tcgtaatcaa acaaaaaacg gtaaaaaaac
    44641 gacggaatgg aaagtttgac cgtgaaatcg cataagcata taaagaagta gccgtgctat
    44701 tgatcagtgt acctaaaaca gtaacaagta cagtgacgaa aagcgcttgg aaaattttat
    44761 cctgcatctg gtcgaacaag tacgtataac caaatatact gaacttttct ggccaaaaac
    44821 tgtacccgtg agtcgacaat atggactcat cggtaaaaga gatggcgata acaaatataa
    44881 atggcaaaat acaggaaata gcaaagagtg caatcattat attagagaaa aaattagccg
    44941 tcttattgaa agagcggact tggactctct ccactttctt ttttttcatt tttttcctcc
    45001 ttagaataat gcagaatcgc tatcaaaacg tcgggcgatc gtatttgtga tcatcaacaa
    45061 gacaaagccg acaactgatt ggtaaagtcc tgcagcagcc gtcataccaa aatctcctgt
    45121 ggatgtcagg ccattgtaga tatacgtatc caaaacttga gtcacatcat ataatgcacc
    45181 ggaattccta ggaatgttat aaaacaggcc aaaatcagct cggaaaatgt ttcctacggc
    45241 taaaatcgtt aaaatcgtca ttagtggaat aagttgtggt atcgtcacat gtttgatctg
    45301 ctgccatttg ctagctccat caaccatagc agcttcataa taagtcggat cgattcccat
    45361 aacagatgca aagtaaataa tgctgttata accaatccct ttccatgtac caatgaacac
    45421 caagataaac ggccaatatt tcggttcatt ataccaattg acagcttctc ctccatgtcc
    45481 agtgatccac tgattgaata ttcctttgtc aggacttaaa aaagcgtaaa caaagtaact
    45541 gataatgacc caagatagaa aataaggtag taaggacatc gtttgataaa ctttaacgag
    45601 tcgtttattt ctcaactcgc tcataatgat tgcaaatacg actgagatca gcagattcaa
    45661 aaggataaat gctacattat ataaaattgt atttttagtg atgagaaatg cttgatccga
    45721 agaaaataaa aatttgaaat tttcccaacc cacccaagga ctttccctca agctagccaa
    45781 gaacccatct gctgaaatat gaaaattttt gaatgctacg acattcgcca ttacaggtat
    45841 gtaaaagaaa aaaatcatcc aaagcatacc cggtacagcc atcaggacaa gtgctttata
    45901 acgccataga ttcataaaaa aatgattgaa cccctttcgt tttttcatct aaaaacccct
    45961 ttcgattcat tcgcaacgta attatagcgc tttcaataat gagaataaat aaacaaagta
    46021 tagggaaaat gaaacaaagt ataggagagg ttgtgaaatc agcgttttgg cctgagtatt
    46081 agagaaaaaa acgggaaaat agttcctcat attttgccgt tttttgagct aataccgagg
    46141 gtcagctgat tgaacaccgt ttatcagagg ttgtgaattc agcgttttgg cctgagtatt
    46201 agggagatcg tgtccttact atctaactct gagtcacaag gaacaatggg gactgtaaca
    46261 aaagtcttgt cacagtccct tattccgaac aaacggtgtt ccagaagtag cttctacgga
    46321 aataagccga aatttcacaa aaaagccatc cgaaagtcag acggacaagt ctgcttttca
    46381 gatggcgcta caactactct gcttattctt ttagctatcc attcaattat ttttctctca
    46441 cttgttctag ctcttctttg gtcatgggtc gatattgccc tttattcaaa tctttaggca
    46501 gccaaaattt tcccatacgg attcttttta aatataagac ttcttttcct actgctttga
    46561 ccattcgctt aacttggtga aactttcctt catgcaaaat cagacggata attgaagttt
    46621 ctgtctcttg atctacttga tcaatttgga gttttgccgg caatgtctgc tcatcgccat
    46681 caataatcag tccttctgca aataaacgga tatcttcttc tgtcattata ccgctaacct
    46741 cagctagata ttctttctcc acatgttttt taggtgatag taactgatgg gcaaacaccc
    46801 cgtcattcgt taaaatcaag aggccctctg tgtctttatc taatcggccg actggaaaaa
    46861 gatcttcccg ataatcctgg tcttccaata aatcgattac ggtttgatca tgattatcct
    46921 gagtagcaga aatgactcct gcaggtttat gcaaaatgta gtaaaaatct ttttgatacg
    46981 taatgatttc tcctaaataa gtaaccgcat cttcgaattc atttacttgc gctttatcgc
    47041 ttttcaccac ttgtccattg acttcgatcg ttcctttttt gattaatcct ttgacttctt
    47101 tgcggctgcc aagtcccata tctgctaaaa acttatctaa acgcatgcgt ttcccccatt
    47161 tcaaaagagc atcaatctag ctcttctgat tcacttattt tatttttaat ttatgtcgta
    47221 aacgcgctat tcctggtcct agtagtcttt ctgccaagcg gattttcaaa gctaaataac
    47281 catacactaa agcccctata cctgctacta caagaatcaa caatagagac tggaatttgc
    47341 tatcttcgtt taaaaaagca ccaaaaatca tctttgtgat ccacgaagcc aaaagcataa
    47401 tcaaggtaag aataaagatc agcaatgtcc tgcgccagac aaaacttggt ttaaagcggg
    47461 ctacttcatg gattctcttt aagatcaagg tacaagacac agcaaatccg atcattgtcg
    47521 ccaataaagg gccgtatact tcaaataaac gaatggctgg gtattgaaga aggagtttca
    47581 ctagaaaccc aataaccaaa taattaattg ccgccttgtt ttcaaacatt ccttgcagca
    47641 tgttggaaac tagcatatat agtcctagga agagtcctac aaaacttgct tggatcagta
    47701 cattacttcc tagagaatcc ggtgtataaa ataatgtatt tagcggatag gcaagtaaca
    47761 taacaccaaa tgtcgccgga aacataaaaa atgaaaacaa ctgtaaattt ccgcttgtca
    47821 attttgccag acctactcga tctttcaacg taacagcttc tgtaatcaac ggtaacccag
    47881 tagacgcgat cgatgttgcc aatgcaataa ctaccatcgt caacttatct ggattggcac
    47941 taaaaatcga aaaaagatcc agtaactgtg cattggaata ctcggtggat gcagacatga
    48001 tcttcataaa agtgaactga tcgactaatt tgaagatcgt tacccctgaa cccacaataa
    48061 taaacggaat cgcttcttta acggtatcta acaacaattc cttcgttgca atatttattt
    48121 tgttttcgct gtagtgaata aacgccgatg tatacgcttg atgtttcttc aaaaaataca
    48181 aaaggacaag aatacttgct agcataccga taaatgccgc gaaagttgat tgcgtgaccg
    48241 ccgtcacata gtcaccatcc atgactttca tgatgatgaa tgtagccaat agcatataaa
    48301 aaatacgtgc cacctgttct acaatctgcg acagcgcata aggcatcatt tcttgattgc
    48361 cttgcaaata ccctcgtatc acactcatac aaggaaaaac caatacagcg atactcaaag
    48421 aacgcatcgt tggaatcagt tcttctccgc caccagaagc atgagctagc caaggagagg
    48481 cgatgtacat gaacaaagca aacaacaggc ctaacccgcc catcatctgt aatgcacgga
    48541 taaataatcg tcgtgaagtg ccatattcat tcaatgaatt atagcgtgca gtttgttttg
    48601 caatcgcagc aggtattcct gctgtagaga tcagtagaaa caatgcatat atattgtatc
    48661 ccatattgaa taatccattg gcagccttag cattttcgcc catccaagca taccagggaa
    48721 tgatatagac agcgcctagc aatcttgaaa tgatattact ggcggtcatc caagcagagc
    48781 ctcgtgccat tttttcttgc ggtgttaatt gatctaatgc tggttttctt tgattatcca
    48841 tcggtcagat tccaactttc tacaaaacat tactatcatt ttaattggta aaacagaaac
    48901 tggcaatcga ttttatataa cttttataag aacaattgtt tttttgaatt cggtttcgtt
    48961 tttttggtaa agtaaagaaa tatacagcct tttatggcta acatttatag gagatatcaa
    49021 tgacacaaga aataaaaaaa ctacccgtta tatttttagg tcttttcttt atcacagttg
    49081 gattgaattg gttcttgctc cctcacgata tagcttccgc cggagtgggc gccatcggac
    49141 atttagttga aacggccttt tctatccaac gctcagttac tgtttggagc atcaatctta
    49201 tgatgctgct tctagccgct gtcctattag gaaaatcagt attttttaag actgtagcgg
    49261 gaagtctgct ttttcctgtt gttttagaga ttgttccaaa agtggaaatg atctcctcac
    49321 atttcttttc actgatttca ggaagtcttt tgttcagtct tggggtttac acattgtaca
    49381 cagtcggggc ctcaaatggc ggtataacga taccgccgat tattttccac aaattttttc
    49441 ggcttccaat gccgcaagga cttttactta ccaatagtct tatcgtcttt ttgaattatt
    49501 atgtttttgg attgttggag acactattcg ttctcctatc tattacagtc agttcattgt
    49561 ttatgaaaat actcatccgc ttgtcccctg tgtcaagaaa atttgaataa agctggattt
    49621 tgtcatagcg gaaacaaacg atatattaaa aagagtgtgc tataataaac caagaaattg
    49681 aataaagcga gggatcaatc aatgagcttc tctttagaag acatccgtca tttactatta
    49741 aaagaaaatc tattaaaaga atttgtttca acaagaggct ggcatcttga tgtaccagaa
    49801 aaagctgaat ttcttcagtt aagttatgat tcaagaaaag ctgatgcttc tactttgttt
    49861 ttctgtaaag gaatgaattt caaagaagaa tatttggatt cagcaatcga acagggtatt
    49921 caatattatg tatcagaaca accatacgaa aattcagcag taggaatcat cgtaacggat
    49981 atccgtaaag caatggcgct tcttgctatg gctttttacg actatccgca aaataaattg
    50041 aaagtgatcg gattcactgg aacaaaaggt aaaacaactg ctgcgtactt tacaaaagca
    50101 atcttggatc acacaacaaa taaaaaaaca gcattgcttt ctactatgaa tacaacgtta
    50161 gatggcaaaa catatttcaa atcccatttg acaacgcctg agtcattaga tttatatcgt
    50221 atgatgtcag aagcagttga aaatggtatg actcatctag tgatggaagt ttcttcacaa
    50281 gcttacaaaa cacaacgcgt atacggcttg actttagatg tcggaatctt cttgaatatc
    50341 tcgcctgacc atatcagtcc gatcgaacat ccgacatttg atgactattt ctattgcaag
    50401 cgacaattga tcttgaattc aaaaacagtt gttttaaatc atgaaagtga ctattttgat
    50461 ttacttaggg aaacagccga tctattccag attccaacga tcacttatgg tcgttcggaa
    50521 gaaagcaatt atcaagtgat ccgttcagat aaaggtactc acggttttac tttatcttct
    50581 catgaagatc gcttagctat ctgcgatact gcttatgata ttttgctggc tggaggattc
    50641 aaccaagaaa atgcagccag tgcgatcatt gccgcagcac taacaggtgc ctccagtcaa
    50701 gatgcacaag acggattaaa agaagctcgt gtaccaggcc gaatggatca attgatccaa
    50761 tccaatggag cgcatgtcta tgtggactat gcacataatt atctaagctt gaaaacattg
    50821 ctgaaatttg ccaaaaatga acatccagat ggccgtgtaa ttgttgtatt aggcagccca
    50881 ggaaacaaag caatctcccg tcgacatgat tttggaaaag tgctatcaga aacagctgac
    50941 atcgcctttt tgacggcaga tgacccagca tttgaagatc cgaaaaaaat cgcggaagaa
    51001 atcaatgaag caattactaa tccagatttg atcgttcatt atgaaatgga tcgtcctgaa
    51061 gcgattcgac gcgctttagc agaaagcgct ccgcaagatt cagtcgttat tgcgggaaaa
    51121 ggcgtggatc cctatcaaaa aatcaatggt gtagatgaac cttatgaagg ggattatgca
    51181 atcgtgaagc ggttgattga agaataatgg tatttatata ctagtggttt cccatttcta
    51241 agaaaaaaag ggactgtgat tttttgtcac agttcctttt ttcttagaaa tcattttaac
    51301 ttttcactag ctaattctgc tgccttttct ctttcttcat ttaataattt attatcatag
    51361 aatttgataa atgggaacca gataatgaat gcgatgattg cacaaatgac tgctaacaca
    51421 gcagctttcc aatcaccacc actaccaaca aatgctccga tcccgactgg tgaaggccac
    51481 ggcatctgtg caagcatcgg tttgacgatt tccagccgaa tggcaaaata agcgagtgta
    51541 gcagaagcca tcggagctaa gaaaaacgga accgctaaat agggattgta gacgattggc
    51601 atcccgaaaa tgattggttc attgatattg aataatcctg gtacaagtga ggcttttcct
    51661 aacactttca gctgatcaga tttcgcgagg aatgcaataa agatgatcaa tcctaaagtc
    51721 gcacctgatc caccaacggt tacataagaa ttgttgaatt ctcctgccaa cggataattt
    51781 gcgccttgtg cgttagctgc catattagct aatacgatcg gggtcaagaa agaagtgatg
    51841 atattcgctc catggatccc tacgatccac aatgcatgga tcaagaaata aatcaccatg
    51901 acaccaagcc atgtattcgt caactgcgta acaaacccaa atgggatagc aatcattttg
    51961 aagatatccg ttcctagtgc aactaataat ccattgatga tcatcaccac aaacgcaatg
    52021 acaaatgttg ggatcagagc agtgaaagaa cgagaaactc ctggcggaac aacatctggc
    52081 atttttatga cccaatttct cttgacacac atacaataca attcgaccgc aataatcgac
    52141 ataataatag ctgtaaagat tcctgaagtt cctaaacgtt cgacaaaaga gcccatccta
    52201 ataccattta ctacagtttc tgtctcattg atagaagcaa tcaagctgat tttaccatca
    52261 gtcatgatca attcagggat acacataaag aatgcaaaaa cagatagtaa tgcccccgtg
    52321 agcggattaa catttaattt ttgttcatct cgttcaattg acgttaattc ataagcaaac
    52381 acaatggcaa agtaaataga taaaatcccc atcgtcattg tattgacgat catgtacaag
    52441 tcactaactt tgaaaaaagt tgcattaaaa aatccttcta aaaatgggaa cggtaatggc
    52501 aaaatattta aaaccaaaaa catcgagcct acaatcgtga aaggaataga agccatcccc
    52561 gctgccatga cagcccgaac gattttaagt tgcgcaattt tccccatagg tcccatcagg
    52621 tatttctgca aaaaatcaaa cattagttat tctcctttcc taaatataac gctttttcat
    52681 attgtttaat acggatatac tgttggtctt ggttgagtga aattttcttt aaacgatact
    52741 gtataaatgc actggcaaaa ataccgctta caacaagaat gaaaacaaat aactgtcctc
    52801 cattgttatt tgccataaaa ggatacaaga atgtaaatcc tgaggtaaac aacactggaa
    52861 tcactaataa attaaagaca ctctggaaca aaaaatacca ctttgtccat ggaacgttcg
    52921 tttggtgttt tcgataaagc tttacttgtt ctcctactgc aggcaaaata gctaaaatca
    52981 gaatcatcgg taaactactt cctaaacttt tagctgatag aagcagaatc atccattgca
    53041 tgttcatgaa aaagaaaaag gcagtcaggt aacgtacgat tagataacga ttgaaataca
    53101 tgtttttcaa actaagttgc tttttttcta attcgatttt cctttttact gtatcctgca
    53161 caatgatcct tcctttctat ttattttttt gatacaaata attcatttcc tgtgcaactt
    53221 ccaataatgt catcgtcgtc atcagatgat cttgtgcatg gaccatgata atttccattt
    53281 ctatttttgt cccgctggca tattctttca gaagttgagt ttgtgactga tgcgcatgaa
    53341 gaatctcttc atttgcttgt cgcaacttct cttctacttc ttcaaacatc tctttacgca
    53401 tcgagcgaaa tgcttcatgt atcagtgtcc gtgcatttcc gctatggaaa atgatatcaa
    53461 aagaagtcac ttgtagtgtt tcactgttta ttttttcagc catctgtttt cctccttatt
    53521 cgatcagttt gataaattta ctgctgaaat tctcaaaaat aggttcagct aagatttcct
    53581 gctgtacttt tagctggtca actaacctaa cgattgcttt agtcacgacc gtaattcctt
    53641 cattttcgac ataagaaggc gaaactaaaa aaacaaaatg aatttcttga tattgatccc
    53701 actgcatccc agaaggaatc aatgcaacgg ctacctttgt ttcgattcca actggaacag
    53761 cgggatgtgg gactgccact gtatcactga atatgatttg tcccatattt tcacgttgct
    53821 ggatctgctt tcgcatttct cttatatatc cttcttcttc atttatgctc agcttttgca
    53881 gcaaatcatg aagaatttct tcctttttcg gttcgtacgt ataagtcttg aaaaattttt
    53941 cagacaactg ttcggtgtaa atctgctttt tttgctgtag agaaaatgct ggtatcggtc
    54001 tatctgagga atgatagggt atagattctc caactacctt tcgtatttta cgaacatcat
    54061 cttcattaaa aaaaatactg acatgtaaaa ctggaatttt gaaaaacatt gtcgaaagat
    54121 caatagaaga aataatcagg tcgattcctt ttaaagttgt ttcattgatc tcataatagc
    54181 cttttacact taccactgta atatttttac cgaattcact gactacgcga ttctttaata
    54241 gttgggcact gccgtaaccc gttgcacaga taatcaatgc atgtagttta tgcgcagctc
    54301 tttctttttc caatgccgcc atgagatgca aagccaaata ggcccattca tcttcattga
    54361 tggtatagtt tttcaaagcc ggcatgttgc tgaaatgcct ttttactgcg tcaaagactt
    54421 tgggattttc tttctttatc tcctcagtca atgggttctc aatgcgaata cctcggctca
    54481 atcgaatcat catcggtgac aaatgatcga gtagtccatt gaaaagctgg agatcctcta
    54541 ctaatgaaaa atgaaattcc tgagacaatc ttttcagaac tttcgctaat tcctttgata
    54601 gttcctgatc attttgattt tctttgtgat tcgacttagc catgagatgt aatgtcaaat
    54661 aagcaatttc ttcttcggga aacgatacac ctgcgattac ctcaatacgt tgaacgatcc
    54721 gctgcgccac ttgatactct actcgcttag aaacttcttg ttcgatgcct aattccttga
    54781 tttcaaaccc ttctcggagc cgtttgatcc ccaaagccaa gtgtaaagtc agattctgta
    54841 tgataaaatc cgaaactttt aacttagctt ctcttgtttc atcgagaatg ataatgacta
    54901 gctcttcaaa actgatgtct gggaaaaaac ggctttgccc taaatattct ttcaatgaat
    54961 ttccataatg gtttccaaaa aaagtatcca tgataaaatg ccgtcgattt ctttcttccc
    55021 cttcgatcca tgtcccttga ccatgcttag aaacgatttt tagtgaatat ggaatcaatc
    55081 gctccttgat ttcttgcatg tcctttgtca aactggaacg actgatataa agctcttctg
    55141 ccaaatcatc cataaaaaga atggcatctt ccaaaagcaa ttggttcaat atatactttt
    55201 gtcgatcttc ggactcataa aatccttgcg gttctctagc atatccaggt actatttctt
    55261 gccgactcaa aaacaagtca aatgtcagtc tttgtaaaat atgcagttgg tagccataac
    55321 ctggtttagc aatgatctta cctccgtttt tttctactaa ctctttgatc cgctgcaagt
    55381 aattacggat tgtccgatca gataataaca attcagaagc taaacgttga ctggtgacat
    55441 actccttctt gtgatcaatc aaatatctca acagcaattt ttccttctgt ttcattatca
    55501 tccactccta ttccatcata tgttctcttc gatcacctct gctaacttct ggatgcctgt
    55561 agggattggg acatacgctt ggaaagggat actaacaaca ggctttccaa cagattctcc
    55621 taattttttg aatttatcca aaaacatcgt cgtttgcggg ctgatcagaa ataaatcaaa
    55681 atcactattc ttaatcatat tatcgccttc tgtagctgaa actgcatcta cgagtacctc
    55741 ttctcttttt tgcttaaaga aatccgttgt ctttgaggcc atcatcgagg atgacattcc
    55801 tgccgcacaa ataatcaatg cttttttcat aaatcaatca ctccttttat ttttataaac
    55861 caagcatatc ttgcaagcgt tttctattca aaatatatat ttccgtagca ttgcggaaaa
    55921 aatgtgtatc atatcttgaa taataatttc tggcaccgtg atatactagt gatagaattt
    55981 tttcaggagg ggatttagtg agtatcacag tgaatatttt gtatacaagt acaaatggac
    56041 aagccagaaa atttgcagaa gaaatggtcg aaagaaacat tgtcaaagcg attcgtgcag
    56101 aagaaggaaa cgagaaatat gactattact ttccactaga agatccagaa tctcttttac
    56161 tgatcgaccg ttggaaagat gaagaagcaa tcgaaaagca tcacaaatcc gaaatgatgg
    56221 ctcaaataaa cgaactccgt aaaaagtata aattaaaaat gaaagtcgaa cgtttcactg
    56281 atttaccgta aaaagataca catggaatga tagcaattta tcatccatgt gtatcttcac
    56341 tttttcctta ttttttattc gatctcatct aatgattcaa accgtgtttt tctcttattt
    56401 ttcggataag tatttcagtc accccaatat acatgattcc taaacatacc ccaaggatat
    56461 tctcaaaaat gcggatcgtt actgctcctg gaaccccgaa taaactggca gtgattgcca
    56521 aagcaccaaa agaattaaaa actgttttat atctataggt agaacaaaca cctaaagcta
    56581 gaccacctaa tataccgacc cagttaaaag gaataaattg gctgatacca ataaataaaa
    56641 cacatccaat caatgagcca atgattcggt ctactgctcg ttctttgaaa ccaatcgaca
    56701 tcaatccata gctagataca atagaagaaa atgcaaaccc tgcccacatc aatcgctgaa
    56761 aagggacata ctctcctgca acgatcaaaa gactaatgcc aaatgcatag atgagcatcc
    56821 aaattttttc ctgcgaatac atgcctttca aaaaaatctc tttaaacaag cttttgtctt
    56881 tgttcttttc tcgatgtttt ctgtaaagga gaactgaaaa ccaacaaaaa aacaaaaata
    56941 ataagctact tgtttgtgta aagaaattct tgttcaacga atctttaggt aacgaataaa
    57001 caataaagag atatgaaaag ccgtacaaag aagcattccc cattttggga tcactagcgg
    57061 ttgccattaa tatgctgctt agtaaaataa aatgaatcaa catgcccata actgaccatt
    57121 tgatcagctg gacatacggt gctactaata gtgagaacat gacgattgct aaacctatga
    57181 tcgaatggga aatcttataa ccaaagtcaa caaaacgaat actcatcaac atacagaata
    57241 aaaccacagc gtatggttta tgcttcgatt caaataatgt tgtaattata atgataaaac
    57301 aaatggcaaa caatacgatg aataatgatc gtaaaaacaa tgaacaaata tacatgcact
    57361 tttctttttt agaagctgct tctcgtattt tttgttttaa aataaacgga tctagttgta
    57421 gagactgata aaaatccacc tgttgtcgtc ctttcttttt acttttattt tttacagtca
    57481 tctatgacag gttgtaaata ctatggaaca tcatatggcg ttgtcatttt cttgtcaact
    57541 atttttccta ttcatgtttt tataaaaaaa catatcgttt tcttgtatga ttaaatcacc
    57601 acaaaataaa caactgagag aacgatatgc tttatgaatg gttctatcaa aaaaattctg
    57661 agatcaatag acaaaaattt gatgattaca gaggtctctt acgaaacctt acagaagaaa
    57721 aaaacattga tcgttgctgc agttctcttc cctgctccat gtgtctgtag aaattgtggt
    57781 tctgctgtgg tagatggaaa taggaaatta atggtggtga aaaacaagaa gaaggaaacc
    57841 attgtccact ttgaataata taatcatatg ccaatggtta tacgcctaaa aaagcagcgc
    57901 tatacctgta aaaactgtcg aagccattgg aacgctcaaa gttattttat ccgtccaagg
    57961 cactcgattt caaatcatgt cagacataaa atcacttctt tactgactga aaaagtgtcg
    58021 ttatttttta tttcgaaaag ttgttaggta tctttgacaa ccgttattcg cacattgaaa
    58081 gagttgagaa gctatttacc aaagtcttcc aaaagaattc tgtcttgagt gttgagggtt
    58141 gtgaatttcg ttctcacgtt tccgttgagg ataaactgag ttttatttcc gcggatggcg
    58201 agacagaaaa attaatcgag aaaatttacc tacacaaaaa attcctcgat taacaaacta
    58261 tttccttagc tgcactaatc ctaaagaaat agaattctta gttacagaca tgaacgccac
    58321 ctactttcag ctcaccaaac atgttctacc aaatgcgaaa ttggtgattg atcgattact
    58381 tggtttttcc acgcctttca aggaggcgta acctttattc acgagttggt tgaagctttc
    58441 cgagacaaaa gacccgactt gtttttctcc ttattgacaa agagccatta aaactagaga
    58501 aaaaattaca actgatcgct gattatttgt agaaagaaaa tcaaagtatt acccaataaa
    58561 cttgagtcat taggcaaaaa acactgcgaa actcaagaat gattttcgca gtgtttttgt
    58621 atatttttta ttaactagta ttactacaaa ggtttatttt tcacttctca acgcagcaca
    58681 aaattgtctt tacttattta ctggttgggt tcaaccttct ctactccgat actaatattt
    58741 gtttgtatac cccttctaaa atcggtagtt tccattcaat tgatgggtac tagttgattt
    58801 taaaaactat gcttattcaa ttttttattt tagctcatat atttcgtttc tttctaaatt
    58861 ttatactgat gaaaacaagt agcacaccca atattgacaa tataaactgg ctaatgatgg
    58921 tttctccagt ttttggaaga tgcttatttc cactgcttgt tggattgttt cctcttatat
    58981 ctgagctatc agcaactttt ctattctctt ttgttaaaaa gatcgccact tcttgttctt
    59041 tttcgatctt gaaagttact ggtgtcgcat ccaattcata ccccgttggc gcttgagttt
    59101 ctaccagctg atatgctcct ggtgctaagc catctatcgc cagttttcca tctgctcctg
    59161 tggttagacc tgactgcaga acggttccat tggcatcttg taactcaaaa acagctcctt
    59221 gcaggacttc tccgctttgg tcatcgatct ttgtcaacac gacaccgcct ggtgtaagtc
    59281 gattttcttt cgtcaattct accaccgctg tctgacttct ttcgatctca aactcgattg
    59341 gtgtcgcatc caattcatac cccgttggcg cttgggtttc taccagctga tacactcctg
    59401 gtgctaagcc gtcaatcgcc agttttccat ctgctcctgt ggttagacct gactgcagaa
    59461 cggttccatt ggcatcttgt aactcaaaaa cagctccttg caggacttcc ccgctttggt
    59521 catcgatctt tgtcaacacg acaccgcctg gtgtaagtcg gtttgctttc gtcaattcta
    59581 ccaccgctgt ctgacttctt tcgatctcaa actcgatcgg tgtcgcatct aattcatacc
    59641 ccgttggcgc ttgagtttct accagctgat atg
//
LOCUS       DAFEIE010000009        56415 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFEIE010000009
VERSION     DAFEIE010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.009"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..305
                     /locus_tag="LP345_000651"
     CDS             <1..305
                     /locus_tag="LP345_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1759458.1"
                     /translation="ITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGIL
                     RRNGLPKSIDFREVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(1171..1701)
                     /locus_tag="LP345_000652"
     CDS             complement(1171..1701)
                     /locus_tag="LP345_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HBL1759459.1"
                     /translation="MRLGLIIKNILNLPKTIYFNYKFLHISDAWRLPILVHRKVRITR
                     KSRGKIEIVLQSGKIVYLGFPVLNTAGNEETIISIEGILRIQGPAFIAQGAHIDIRKN
                     AVLDIGSKFNSTGKMSIICFKEIQFKDGCTVSWDTLFMDTDSHTIFELNTHRILNKNN
                     KIVIGKHCWIGAKSVI"
     gene            complement(1698..2315)
                     /locus_tag="LP345_000653"
     CDS             complement(1698..2315)
                     /locus_tag="LP345_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL1759460.1"
                     /translation="MIIVIAEIITDILYKLYEPFGFAVLLTILGLVYFMYATDGIAAG
                     EGYKRILMELYLHLKKDRKYRKVCALIFYTAMILFTTLINRTIWLNPLSDVMGDWWIY
                     KYNTTTGTKELSTACLENIILFIPYVYMVMSIKYENIKKPKIWSSIVYGGKIAFYFSA
                     IIEFLQLFLRLGTFQISDFVYNTLGGILGVILYKLILITKRDGER"
     gene            complement(2897..3118)
                     /locus_tag="LP345_000654"
     CDS             complement(2897..3118)
                     /locus_tag="LP345_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HBL1759461.1"
                     /translation="MGSSERIKIGNNVFIGMKSRILKGVHIGNNVVIGANSLVNKDVS
                     DDCVVAGNLAKVIMSLDEYYKKINNMKNP"
     gene            complement(3296..4828)
                     /locus_tag="LP345_000655"
     CDS             complement(3296..4828)
                     /locus_tag="LP345_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1759462.1"
                     /translation="MIINRKQNAKRNIITGTIFKLYQIIIPFFMRTLMIYQMGMEYAG
                     LNNLFTSIFQMLNLAELGIGAALTVSMYKPIAEDNRKEICALLNAYKKYFSIIGWIVF
                     TLGLLCIPFLRFLVKGSIPGNLNMTVLYLMYLINTVLSYWLFSYRKSLIYAHQRNDVI
                     NVSMLITFTFQFVMQAYVLIFLKNYYLYLLASILGQIVLNLMCAVVSQKMYPDYTPVG
                     ELEKETIDDIIKKVKGLVTNKVGGTILRSSDSIIISSFLGLSVLAIYQNYYFIISAIM
                     SIFAIIYESCIAGIGNSLIVESQEKNYIDFCDITTIIGWFLAISCACFITLFQPFMII
                     WVGSDNLMSISFVIFMIVHFFLYEIDQLIGLYKDAAGIWYADRFRPLITAMINIVLNI
                     ILVNWFGLYGVLAATIVSVLLVDLPWLLYNVFQNIFKFESAGKYVWKLISLCVIAFVA
                     SYLSYFACSYVNIGNFKVISLVINLVISVVISILVILLFNIRNKKFKYILKVLTSVLV
                     KR"
     gene            complement(4964..6049)
                     /locus_tag="LP345_000656"
     CDS             complement(4964..6049)
                     /locus_tag="LP345_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1759463.1"
                     /translation="MKKICFISGVISRSGGTERVGSIIANSLSDLGYDVTILSFWNSG
                     EPYFGLDKTIKVDYMLNPKTEGKLYRTYLYPVWKLHKYICKNEFDIVIDIDTLLSLYT
                     TRAIKGTKCKLISWEHFNYWTMEMLKEKKRFKAKKLIKKYAKRLVVLTEEDRQKHIDE
                     YSLSEDFVITMPNPCISNIEYEYHYDKKRFLAVGRLVEEKNFADMISAWKIVEKKVDD
                     WDLIIVGKGELEKDLRQQIKDLNLQRVTIAGHSDHVEEYYKSASCYVLSSVYEGFPMV
                     ILEAQSYGLPVISYDCKTGPRDLVHHNFNGMLVEDKNIDQLAKSMIMFTKNTDLAMRM
                     SLNAYNNVQKFNLKEITKQWVALIENV"
     gene            complement(6064..6783)
                     /locus_tag="LP345_000657"
     CDS             complement(6064..6783)
                     /locus_tag="LP345_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL1759464.1"
                     /translation="MIPKKIHYCWFGGNPLPKKDRKCIESWKKYCPDYEIIEWNESNY
                     DLNKNRYMADAYKERKWGFVPDYARFDIIYNHGGFYLDTDVELIKSLDILRENHAYMG
                     FEGEIWVNGGIGFGAEEGHSVIKGLRDIYDSLSFYQNDGTLNLKPSPYYITDYLESIG
                     LVRDNSEQIINGLHIYPTDYFAAKDYDTGKIYKTSNTISIHQYNASWKTPKQKFVYRL
                     KSTIGQKKFNRLLALKKFLHL"
     gene            complement(6780..8090)
                     /locus_tag="LP345_000658"
     CDS             complement(6780..8090)
                     /locus_tag="LP345_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBL1759465.1"
                     /translation="MRISIKRWSGADWTLFTLAFFAISIVLVYTFNAPRAILYLGDII
                     NIFVLLNALSFRRRKGIYASKNEMLIVLFLLVSICSSVINLENIGLIIWGIRNNTRMF
                     IVYINCATYLTIKDYYKVFAIIEKLFWISLPLCLIERFMVTYPTGTIVGDMIGGVFWN
                     YSGCNMPLNLILCVTVTVVTIGYFKGEKNFIHFILCVCAALFMSALAELKVFIPELFI
                     IFVAIVFTLKVDFKVVIKILSCVILVSIVLSFFITIFITLNDNGQSYADNFTIQGLLE
                     YASRDSGYDGVGDLNRITGISRVVDEIFNNNFRLVLMGVGIGNAEFTNFFVSEFYKSF
                     GNLHYQYFHHIWLFIEVGILGVSIFLFFIIKTFFNAKRSFMKDKDASLVKVIAIMSVF
                     FFVYNTTLRGETTGPLIYMILAMPEVVKRKEHYYSEKNTKGEIL"
     gene            complement(8117..8707)
                     /locus_tag="LP345_000659"
     CDS             complement(8117..8707)
                     /locus_tag="LP345_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HBL1759466.1"
                     /translation="MEISSKEYLKAVLRMEKNLYIESKGQHTKLLKIMKSHPDYNAWR
                     YTRRMRITSYYYSKRKKNIIYAIMYIVSCRRMNSLGRKCGIECGENVFDEGVRFYHTQ
                     GIVINGNAIIGKNCYLYGNNCIGNDGIDPKCPVIGNNVRVCVGAKIIGNVKIANNVVV
                     AAGAIVIKDCLENGAILAGVPAKIIGYVNLTKVFLE"
     gene            complement(9025..10086)
                     /locus_tag="LP345_000660"
     CDS             complement(9025..10086)
                     /locus_tag="LP345_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1759467.1"
                     /translation="MNSSDLISVIIPVYNVEKYVGSCLESVCNQTYKNLDIIIVDDGS
                     KDSSNKICEDYALKDSRIRIIHKNNAGLGLARNTGLEHVKGKYVAFIDSDDFVAANYI
                     EAMLNGIKRSNADTCYAGYYEYYDDNNIISKPARYDSTIFTNNAIIEKVLLGMIGTEP
                     SYKVDFILPMSVWHALYSSEIIQQHNIKFPSERDYISEDIIFHISYLQHSKITSFIKD
                     CIYYYRCNNNNSLTHNFRDNEFDCNIELVKKIEGDLSYILENEIFVNKTRRLLLGRCR
                     TCIQKAVRYASFNKEFDLNSYLSKILMNDELIACIHSYPYKQNPIKQRIFNYFLLNQS
                     IIGVKTLAYLSGMGRNRRF"
     gene            complement(10654..11721)
                     /locus_tag="LP345_000661"
     CDS             complement(10654..11721)
                     /locus_tag="LP345_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1759468.1"
                     /translation="MQRVLMIGNDSSVKGGITSIITQMLNFNWEKKNIEMTFIPSYKG
                     GNAIFKSLYFMYAFAKIIGISLLSKPNIIHMHMSYRGSFSRKYVLNKWFRLLNIPVII
                     HLHGSEFKKWYDSVSVKKQNQIRLLLRESDSTIVLGEKWKKIIKEIEPNCKTVVVENS
                     IVVPEYTIKWNSKMCRFLFMGVLIKRKGVHDLVEAVKNIAEQYPEKKFIFEIAGAGDE
                     EISLKELIEEYNLQSYFEFTGWVVGEKKEECYRRSNVMILPSYNEGLPISILEAISYG
                     MPVIATDVGDISSAVRDGENGYLFQPGDVSALTSAILKINDKDKYVKFSRCSKDLAIT
                     KFNDGNFFDRILNLYQKGSKE"
     gene            complement(11741..12220)
                     /locus_tag="LP345_000662"
     CDS             complement(11741..12220)
                     /locus_tag="LP345_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta(1,3)galactosyltransferase EpsH"
                     /protein_id="HBL1759469.1"
                     /translation="MIFITLGSQKFQFDRLLKAIDDLIEKGVIIESTFAQSGYSDYKP
                     LNYSYKAFLNRDEFTETMQKAEMVITHGGTGAIIGAVKKGKRVIAVPRLAKYGEHVDD
                     HQLQLIRQFDEMNIIYPCYELENLEDAVKETRVRMFNKYVSNTETIINSIEVLIEKI"
     gene            complement(12237..12698)
                     /locus_tag="LP345_000663"
     CDS             complement(12237..12698)
                     /locus_tag="LP345_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1759470.1"
                     /translation="MNKKICFAASSGGHYEQLMMLKPLMEKYESFVITEQTEYSAESK
                     GEKTYYMRQVNRKEKFFLCTILINLFKSIIIYIKEKPDLVICTGVLAMIPICLITKMM
                     GKKLIYIESFAKVTSPTQTGKLMYHFADQFYVQWETMLQFYPNDIYLGGIY"
     gene            complement(12712..13962)
                     /locus_tag="LP345_000664"
     CDS             complement(12712..13962)
                     /locus_tag="LP345_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBL1759471.1"
                     /translation="MKKKYNIAVAGTGYVGLSIATLLAQHHQVTAVDIIPEKIELINK
                     RKSPIQDEYIEKYLTEKELDLTATLDARSAYKSADFVVIATPTNYDSRTQHFDTSAVE
                     SVIEVVMDVNPDTIMVIKSTIPVGYTESVRETTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMTDERLLNAAHVFATLLQKSAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPGNLIEAIVESNRTRKDFIADRVLQMAGYYNYAEYNQYDVNRENPVLIGIYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPALKDGETFFGSKVINDLEQFKAMCDSII
                     ANRYDTCLDDIKEKVYTRDIFQRD"
     gene            complement(14340..15791)
                     /locus_tag="LP345_000665"
     CDS             complement(14340..15791)
                     /locus_tag="LP345_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL1759472.1"
                     /translation="MYKKSSRGWVKHIDFIILDLLCIQLAFYLSYVLRQVDWNPYVIP
                     MYQNMAVFIELADLLVIFMFEAYRGVLKRGYYIEFASSVKQAIMLVLLGSLYLISVQG
                     GNDYSRVVLFLMGGLYVVITYITRLLWKHYLKHKMKNEGNKSLIIVTSSSIAEVVIRN
                     VKEHNYKMYKINGVIIIDKSMIGEDVEGVTVVSDSKNAADYLCQGWVDEVFIILNKST
                     SCMKEFIERCSEMGLTVHLNLAKVSDSALGKQSIGRIGEYTVLTTSINVMTTQQAFIK
                     RTIDILAGIVGCIATGIIFIFIAPLIYINSPGPIFFAQERIGQNGKPFKMYKFRSMYM
                     DAEERKVELMKENKMSNNLMFKMEFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FFNVLTGKMSLIGFRPCLKSEYEEYDYHHRARIAIKPGITGMWQVSGRSDITDFEEVA
                     KLDTEYIKNWSMGLDFKILFKTVKTVLQRGGSM"
     gene            complement(16114..16878)
                     /locus_tag="LP345_000666"
     CDS             complement(16114..16878)
                     /locus_tag="LP345_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBL1759473.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNVHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(16906..17604)
                     /locus_tag="LP345_000667"
     CDS             complement(16906..17604)
                     /locus_tag="LP345_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBL1759474.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILSEARQLFDV
                     VIFDMPPVVAVTDAQIMSLKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(17616..18395)
                     /locus_tag="LP345_000668"
     CDS             complement(17616..18395)
                     /locus_tag="LP345_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBL1759475.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(18411..19355)
                     /locus_tag="LP345_000669"
     CDS             complement(18411..19355)
                     /locus_tag="LP345_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1759476.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(19401..20180)
                     /locus_tag="LP345_000670"
     CDS             complement(19401..20180)
                     /locus_tag="LP345_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759477.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQYHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            complement(20560..22635)
                     /locus_tag="LP345_000671"
     CDS             complement(20560..22635)
                     /locus_tag="LP345_000671"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBL1759478.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLAGVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLEDVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(22637..23554)
                     /gene="glyQ"
                     /locus_tag="LP345_000672"
     CDS             complement(22637..23554)
                     /gene="glyQ"
                     /locus_tag="LP345_000672"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBL1759479.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(23940..24758)
                     /gene="recO"
                     /locus_tag="LP345_000673"
     CDS             complement(23940..24758)
                     /gene="recO"
                     /locus_tag="LP345_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBL1759480.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKEIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFINQMKSWAHVLKTSEKDMSEKEKETPEKEE"
     gene            complement(24901..25800)
                     /gene="era"
                     /locus_tag="LP345_000674"
     CDS             complement(24901..25800)
                     /gene="era"
                     /locus_tag="LP345_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBL1759481.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(25815..26210)
                     /locus_tag="LP345_000675"
     CDS             complement(25815..26210)
                     /locus_tag="LP345_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBL1759482.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFTVIVGLILFVPKIYHLLFN"
     gene            complement(26194..26670)
                     /gene="ybeY"
                     /locus_tag="LP345_000676"
     CDS             complement(26194..26670)
                     /gene="ybeY"
                     /locus_tag="LP345_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBL1759483.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(26699..28891)
                     /locus_tag="LP345_000677"
     CDS             complement(26699..28891)
                     /locus_tag="LP345_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBL1759484.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKAIDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNGKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(28915..29886)
                     /locus_tag="LP345_000678"
     CDS             complement(28915..29886)
                     /locus_tag="LP345_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBL1759485.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            30591..31970
                     /gene="brnQ"
                     /locus_tag="LP345_000679"
     CDS             30591..31970
                     /gene="brnQ"
                     /locus_tag="LP345_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL1759486.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(32126..32572)
                     /locus_tag="LP345_000680"
     CDS             complement(32126..32572)
                     /locus_tag="LP345_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBL1759487.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(32599..32775)
                     /locus_tag="LP345_000681"
     CDS             complement(32599..32775)
                     /locus_tag="LP345_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBL1759488.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(32937..33365)
                     /locus_tag="LP345_000682"
     CDS             complement(32937..33365)
                     /locus_tag="LP345_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL1759489.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            33457..34317
                     /locus_tag="LP345_000683"
     CDS             33457..34317
                     /locus_tag="LP345_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBL1759490.1"
                     /translation="MSSDSTEIITFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(34411..34761)
                     /locus_tag="LP345_000684"
     CDS             complement(34411..34761)
                     /locus_tag="LP345_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL1759491.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(34777..36504)
                     /locus_tag="LP345_000685"
     CDS             complement(34777..36504)
                     /locus_tag="LP345_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBL1759492.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            complement(36717..37643)
                     /gene="trxB"
                     /locus_tag="LP345_000686"
     CDS             complement(36717..37643)
                     /gene="trxB"
                     /locus_tag="LP345_000686"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBL1759493.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(37788..39224)
                     /locus_tag="LP345_000687"
     CDS             complement(37788..39224)
                     /locus_tag="LP345_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL1759494.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(39221..40624)
                     /locus_tag="LP345_000688"
     CDS             complement(39221..40624)
                     /locus_tag="LP345_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL1759495.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            40854..41756
                     /locus_tag="LP345_000689"
     CDS             40854..41756
                     /locus_tag="LP345_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1759496.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(41797..43683)
                     /locus_tag="LP345_000690"
     CDS             complement(41797..43683)
                     /locus_tag="LP345_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1759497.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAADGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMSLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVINYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(43780..44632)
                     /locus_tag="LP345_000691"
                     /pseudo
     CDS             complement(43780..44632)
                     /locus_tag="LP345_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(44967..46751)
                     /locus_tag="LP345_000692"
     CDS             complement(44967..46751)
                     /locus_tag="LP345_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759498.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQEFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(46751..48502)
                     /locus_tag="LP345_000693"
     CDS             complement(46751..48502)
                     /locus_tag="LP345_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1759499.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLERELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            complement(48644..48868)
                     /locus_tag="LP345_000694"
     CDS             complement(48644..48868)
                     /locus_tag="LP345_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBL1759500.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            49120..50706
                     /locus_tag="LP345_000695"
     CDS             49120..50706
                     /locus_tag="LP345_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBL1759501.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            complement(50772..52547)
                     /locus_tag="LP345_000696"
     CDS             complement(50772..52547)
                     /locus_tag="LP345_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBL1759502.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(52758..53660)
                     /locus_tag="LP345_000697"
     CDS             complement(52758..53660)
                     /locus_tag="LP345_000697"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBL1759503.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            53939..56284
                     /locus_tag="LP345_000698"
     CDS             53939..56284
                     /locus_tag="LP345_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL1759504.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKNEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
BASE COUNT        16724 a        11741 c         9135 g        18815 t
ORIGIN      
        1 ctattacgtt tgactgtgga aaagaatttt ctaactggaa agccattagt aaccaacatg
       61 atattgatat atattttgcg gaccctggaa caccttctca acgcccatta aacgaaaatt
      121 ctaacgggat tctgcgtcgt aatggactgc cgaaatcaat agattttaga gaagtgaatc
      181 agacatttat ttccagtgtc agcaatcaac gcaatcatat tccaagaaaa tcattgaatt
      241 acagaacacc aatcgaaata tttttgagct atgtacaaga agcattttat tctagcttaa
      301 tttgacaaat catataattt aaaattaaca ttgattctcc tatgaaaata tcttttacct
      361 ttctcctgtg aaaaggaaat ttcctttttt atagtgttat tgatataatc agaatattca
      421 tcaaactctg tatctggagt taaaaatcta cagtaacatc tataagcttt gctagtaatc
      481 ttcttgggtt ctctctccat tgtcaagcaa catcaaaaca cctacttact attcgattct
      541 tttctgccaa aaacgagtca gcatcactca caacttatgt gttgctgact ccgactagtc
      601 ctttgttcaa tatcaactta ttaaacagat ataatatttt tctttatttc gtatactcca
      661 agacttccat ctttctttca tcttatctct gaaaaaaaca cagcaaagtg cccttaataa
      721 atatacatta gaatttgcaa attttttcat cttaagatat atcctattca tattctttac
      781 aatcctaatg ggtgattaca aatctattta gttcaagttc tacattataa acacctttct
      841 tgatagtatc atctgctgca caagcgatgt cgatccactt attaggggat ttacgtgctc
      901 aaaagtggct attccttttg ggaagtccat ccataataat ggtccatgga tttttttagg
      961 gtcttgtcgt tcaaatttct caaaaacttt attatacttc catagtttta taattatttg
     1021 gtttcacttt ggctcgttca aacaccaact tgtatttctt ttcaacgttc gaactggagc
     1081 cccccctata atctcattat tattttcatg actttttact accgtggaat tacaagcaac
     1141 aacaatatta tctgctaaat gaacaccttt ctatatcacg ctttttgctc caatccaaca
     1201 atgtttacct ataactattt tattattttt attcaaaatc ctatgagtat tcaattcaaa
     1261 aatcgtatgt gaatcggtat ccataaataa tgtatcccac gatactgtac agccatcttt
     1321 gaattgaatt tccttaaagc aaattatact catttttcct gtcgaattaa actttgaccc
     1381 aatatctaaa actgcatttt tccttatgtc aatatgagcc ccttgtgcga taaacgctgg
     1441 cccttgtatt cttagtattc cttcaatact tataatcgtt tcttcatttc ccgcagtatt
     1501 taatactgga aagcccaaat aaactatttt tccagattgt aatactatct caattttccc
     1561 tctcgatttg cgtgtaatcc gtactttacg atgcaccaaa ataggtaatc tccacgcatc
     1621 tgaaatatga agaaatttat aattgaagta tatcgtttta ggtaaattta atatattctt
     1681 tattatcaat ccgagtctca tctttcacca tctctttttg taatcaaaat tagtttataa
     1741 aggattacac ccaatatacc gcccaacgta ttatatacaa aatccgaaat ttgaaacgtt
     1801 cctagcctca aaaaaagttg taaaaattca attattgctg aaaaataaaa tgcaattttt
     1861 cctccatata ctattgagga ccatattttg ggtttcttta tattttcata tttaatagac
     1921 attaccatat aaacatatgg aataaaaaga ataatatttt ctaaacacgc tgtagataac
     1981 tcttttgttc cagttgttgt attatactta taaatccacc agtctcccat aacatcagat
     2041 aaaggattta accaaattgt tcgattgatt aatgttgtaa ataaaatcat cgcagtatag
     2101 aatatcaaag cacaaacttt tctatatttt ctatccttct ttaaatgaag ataaagttcc
     2161 attagtatac gtttatagcc ctcacctgca gcaatgccat ctgttgcata cataaaatag
     2221 accagtccta aaattgtcaa taaaacagca aacccaaagg gttcatataa tttatataat
     2281 atatctgtaa taatttctgc aatcactatt atcataatta tttctccaat atcaagtata
     2341 cacttatcgc ttccaattac acatgatcat attagagtgt attatcacat tctctaatat
     2401 tcaatttatt tttcctaaaa tattcgaaat aatcgtcttg ataacgagta agtattttta
     2461 tacgattgat aacatagtaa caatattttt aattatagta aaaaatcatc tgcctttttc
     2521 atccacctaa tcttattttt cattttattc aacatcctta aataaacttc cgttcctaag
     2581 ctctataata tcttcttaaa aaataatatt atggtgtcgt tttcaaactc gtaatctttt
     2641 acattggaaa aatacatact tttctcaatg tagcaactcc tatctcacag tattcaaaaa
     2701 ttcttcaata ttatgaaata cttgtgcatg ttctttaaat accttgtcag tctgtttata
     2761 atcccctact aaattttgca ttgctcccaa ctcttcgaca aattgtcatc tccatctgta
     2821 aacagcccta aaaactcata taatgctttt tcatcaatat ttttcccata ttattctcgg
     2881 tatagtttca caagttttac ggattcttca tattgtttat ctttttataa tattcatcta
     2941 gggacataat tacttttgct agatttcctg caacaacaca atcgtctgat acgtccttgt
     3001 ttactaaact atttgcacct ataactacat tatttcctat atgtacaccc tttagtattc
     3061 tagacttcat tcctataaaa acattattac ctattttgat cctctccgat gatcccaaag
     3121 cttctccata ctacttttaa aaccgatcaa tcataaacat gagtcaaaat tgtaactcct
     3181 tcatatcatc tccaatttca acaagagtct tcgttggaac aaaaactata catcgttcgc
     3241 ctattcggca gcctaaaaat tgtagttact ttatatatca ttctgatgtc tcttctcatc
     3301 tttttaccaa taccgacgta agaactttca aaatatactt aaacttctta ttacggatat
     3361 taaacagaag aataactaaa atcgatatga caaccgatat aactaaattt atcactaaac
     3421 ttatcacttt gaaatttccg atattaacat acgaacaagc aaaataactt aaataagaag
     3481 caacaaaagc tattacacac aaacttatga gcttccaaac atatttacct gccgattcaa
     3541 atttaaatat attttggaaa acattatata ataaccaggg taaatcaacc aacaatactg
     3601 aaacaatggt tgccgccaaa actccatata atccgaacca attaacgagg atgatattta
     3661 atacaatgtt tatcattgct gtaattaatg gtctaaacct gtctgcgtac catattccag
     3721 cagcatcttt gtataaccca attaactgat caatttcata taagaaaaaa tgaactatca
     3781 taaatataac aaatgaaata ctcataagat tatcacttcc cacccagata atcatgaacg
     3841 gctgaaataa tgtaataaag catgcacaac taattgccag aaaccaacct ataattgttg
     3901 taatatcaca aaaatctata taattttttt cttgactttc tacaataaga ctgttaccta
     3961 tacctgctat acatgattca taaattattg caaatatact cattatggca gaaataataa
     4021 agtaataatt ctgataaatc gcaagtactg aaagacctaa gaaagatgaa ataataattg
     4081 aatctgaaga tcgtaatatt gtaccgccta ccttgtttgt aactaatcct tttacttttt
     4141 ttataatatc gtcaatagtt tctttctcta actcaccaac aggagtataa tcaggataca
     4201 tcttttgaga aacaacagca cacattaagt taagaactat ttgtcccaaa atagaagcca
     4261 ataaatacaa atagtaattt tttaagaaaa tcagaacata tgcctgcatt acaaattgga
     4321 atgtaaaagt aattagcata gacacgttaa ttacatcatt tctttgatgt gcatatatta
     4381 gactctttct atatgaaaat aaccaatacg acaaaacagt atttatcaaa tacattaaat
     4441 acaaaactgt catatttaaa tttccaggaa tcgaaccttt aactaaaaat ctcaaaaaag
     4501 gaatgcataa caatcctaat gtaaacacta tccatccaat aattgaaaag tactttttat
     4561 atgcgttcag taaagcacaa atctcttttc tattgtcttc tgctataggt ttatacatac
     4621 ttacagttag tgcagcacct attcccaatt ccgctaaatt taacatttga aatatagatg
     4681 tgaacaggtt gttcaatcca gcatactcca ttcccatctg ataaatcata agtgtacgca
     4741 taaaaaaggg aatgataatc tgatataact taaaaattgt tccagtaatt atattccttt
     4801 tagcattttg tttacgatta attatcatat catatggctc caaactttct attttttatt
     4861 gttacctaat actatataat ttctaaaatc ttgaaatgta ataggtttct tctagctctt
     4921 tgattaatta cgctaatttt catgtttgga caaccacaaa aaactataca ttttcaatca
     4981 aagcaaccca ttgttttgta atttctttca aattaaattt ttgtacatta ttatatgcgt
     5041 tcagtgacat tctcattgct aaatcagtat tcttagtaaa cattatcatg ctcttagcta
     5101 attggtctat attcttatct tcaaccaaca tcccattaaa attatgatgt accaaatctc
     5161 tcggaccagt tttacaatca taagaaataa ctggtaatcc ataagactgt gcttctaata
     5221 taaccatagg aaatccttca taaacagaac taagcacata acaagatgca gatttataat
     5281 attcctccac atggtctgaa tgccctgcta tagttactct ttgcagattt aaatctttta
     5341 tctgctggcg aagatctttt tctaattcac cttttcctac aatgataaga tcccaatcat
     5401 ctactttttt ttctacaatt ttccaagcac ttatcatgtc agcaaaattt ttctcttcca
     5461 ctaatcgccc tactgcaaga aatctctttt tatcataatg atattcgtac tcgatattag
     5521 atatacacgg atttggcata gttataacaa aatcttctga taaactatat tcatcaatat
     5581 gtttttgacg atcttcttct gtgagaacca caagcctctt tgcatatttt tttatcaatt
     5641 ttttagcctt gaatctcttc ttttctttca gcatttccat tgtccagtaa ttaaaatgtt
     5701 cccaagaaat caatttgcac tttgttcctt taattgccct tgtagtatac aaagacaaca
     5761 aagtatcaat atcaattact atatcaaatt catttttgca tatatacttg tgcaatttcc
     5821 aaaccggata taaataagtt ctatataatt ttccctccgt tttaggattt aacatataat
     5881 caaccttaat cgtcttatct aacccaaaat aaggctctcc actattccaa aagcttaaaa
     5941 tagtgacatc ataacctaaa tcagacaagc tattggcaat aatactccct actctttcag
     6001 ttcccccaga acgagaaatt acaccactaa tgaaacaaat tttcttcaaa gtacttttct
     6061 cctttataag tgtaaaaatt ttttcagtgc aagtaacctg ttaaattttt tttgtccaat
     6121 tgttgatttt aatctataaa caaatttttg tttaggtgtt ttccaagatg cattatattg
     6181 atgaatgctt attgtattac tagttttata aatttttcca gtatcataat ccttggcagc
     6241 aaaataatcc gtaggataga tatgcaggcc atttattatt tgttcgctgt tatcgcgaac
     6301 caatccaata gattcaagat aatctgtaat ataatacgga ctcggtttca agttcaatgt
     6361 accatcattt tgataaaaac ttaatgaatc gtaaatatcc cttaaacctt taataacaga
     6421 atgtccttct tctgcaccaa aaccaatacc gccattaacc cagatttccc cttcaaatcc
     6481 catataggca tgattttcac gaagtatatc taacgactta attagctcaa catctgtatc
     6541 taaataaaat ccaccatgat tataaataat atcaaatctt gcataatctg gaacaaaacc
     6601 ccatttacgt tctttatatg catcggccat ataacggttc ttatttaaat cataatttga
     6661 ttcattccat tcaataatct cataatcagg gcaatacttt ttccagcttt ctatgcactt
     6721 tctatctttt ttcggaagtg gatttccccc gaaccaacag taatgtatct tcttaggaat
     6781 cataatatct ctccttttgt atttttttca ctataataat gctctttcct tttcacaact
     6841 tcaggcatgg ctaaaatcat ataaatcagt ggccccgttg tttcacccct aagtgttgtg
     6901 ttatacacaa aaaagaatac cgacataatt gcaataactt taacaagact tgcatcttta
     6961 tccttcataa aagatctttt tgcattgaaa aatgtcttta ttataaaaaa taggaatatc
     7021 gaaactccta atattccaac ttctataaat aaccaaatat gatgaaaata ctgataatga
     7081 agattaccaa acgatttata aaactcactg acaaaaaaat tggtaaactc tgcattgcca
     7141 atgcctactc ccattaggac taatctaaaa ttattattaa atatttcatc tactactcta
     7201 gagataccag ttattcgatt taaatcacca acaccatcat atccagaatc tcttgacgca
     7261 tattctaaaa gaccttgaat tgtgaaatta tcagcatagc tttgtccatt atcgttcaat
     7321 gtaataaata ttgttataaa aaaggataat actatcgaca caagtattac gcatgataat
     7381 atcttgatca ctactttaaa atcaactttt aaagtgaata ctattgcaac aaatattata
     7441 aataattcag gaataaaaac tttcaattca gctaatgcag acataaaaag tgctgcacaa
     7501 acacataaaa taaaatggat gaaatttttt tctcccttga aatatccgat tgtaacaaca
     7561 gtaactgtca cacacaaaat taaattcaat ggcatattac aacctgaata attccaaaaa
     7621 actccaccta tcatatctcc tacaattgtt ccagttggat aggtgaccat gaatctttca
     7681 attaaacaaa gtggcagtga aatccagaat aatttttcaa ttatagcgaa tactttatag
     7741 taatctttaa ttgttaaata tgttgcacaa tttatatata ctatgaacat acgagtgtta
     7801 tttcgtatcc cccagataat caatcctata ttttctaaat taataactga gctacaaata
     7861 gaaactagta aaaacaaaac tatcagcatc tcatttttgc tagcatatat tccttttctg
     7921 cgtctaaagc taagtgcatt taataacaca aagatattaa ttatatctcc caaatataaa
     7981 attgctcttg gggcgttaaa agtatataca agaactatgg agattgcaaa aaatgccaac
     8041 gtgaacaatg tccaatctgc tcctgaccat ctttttattg aaatacgcat cgttattcac
     8101 cttctttcgc taaaaattat tctaaaaata cttttgttaa attaacatac cctattattt
     8161 ttgccggtac acctgcaaga attgcaccat tctctagaca atctttgata acaatagctc
     8221 ctgccgcaac aactacattg ttagctattt ttacattacc aataatcttt gcacccacgc
     8281 atacacgtac attatttcca attacaggac acttaggatc gattccatca tttccaatac
     8341 agttattccc atataagtaa caattttttc ctattatggc gttaccatta ataacaattc
     8401 cttgtgtatg gtaaaatctt acaccttcat caaatacatt ttcaccacac tctataccac
     8461 attttcttcc caaactattc attcttctgc aagacacaat atacataatc gcataaatga
     8521 tatttttctt tctctttgaa taataataag atgtaattct cattcgacga gtataccgcc
     8581 aagcgttgta gtccggatgt gatttcatta tttttagtaa ttttgtgtgt tgtcctttag
     8641 attctatata tagattcttt tccatacgaa gaaccgcttt taaatattct ttactgctaa
     8701 tttccattca tatctcctat taattcaatt tatacttaac aattttattc ggatttcttg
     8761 caacaagagc atcattcaat gctactgaat ctacaacgat ggatatgtta tcttcatcgt
     8821 tgattccacc ggatacaata ttacttataa aaatcgtaac attttttcca aaagaaggga
     8881 tgtccgtgat gtataatgcc cattttccga tatttccagt tatttaaacc taacgaattt
     8941 ttacaatagt acaagtatca caatcattaa tatataactg gaatataaat ctccaaaaat
     9001 tcactatagt acagtttttt atgattaaaa tctcctattt ctacccattc cgcttaaata
     9061 tgctaatgtt ttaaccccaa taatggattg gtttagtaaa aaatagttaa atattcgttg
     9121 tttaattgga ttttgtttat atgggtatga gtgaatacag gcaatcaact catcgttcat
     9181 aagtatctta gacaaatagg agtttaaatc aaattcttta ttaaaactag catatctaac
     9241 tgccttttga atacaagtac gacagcgtcc caacaaaagt ctccttgttt tgtttacaaa
     9301 tatctcattt tctaatatat agcttaaatc gccttcaatt tttttaacta attcaatatt
     9361 acaatcgaac tcattatctc taaaattatg tgtcaatgaa ttattattat tacatctata
     9421 ataatagata caatctttaa taaaacttgt tatttttgaa tgttgcaaat atgaaatatg
     9481 gaatatgata tcttcagata tataatccct ttctgacgga aacttgatat tgtgctgttg
     9541 aattatctca gatgaataca gcgcatgcca aactgacatt ggcaatataa aatcgacttt
     9601 ataactcggc tcagtgccaa tcattccaag caacactttt tcaattatag cgttatttgt
     9661 aaatatcgta ctatcatatc ttgctggctt tgaaataata ttattatcat cataatattc
     9721 ataatatcca gcataacatg tgtctgcatt actccttttt ataccattta acattgcttc
     9781 aatataatta gctgcaacaa aatcatcaga atcaataaaa gcaacatatt ttccttttac
     9841 atgttcaagt cctgtatttc ttgccaatcc caagccagca ttatttttat gaataatacg
     9901 aatccttgaa tcctttaatg catagtcttc acatatttta ttagatgaat ccttagatcc
     9961 atcatccaca attataatat ctaggttctt atatgtttga ttacacactg attccaaaca
    10021 acttcctaca tacttttcaa cattatatac aggtatgatt acactaatta gatcactcga
    10081 attcatcctt ctatcctttc actcacgttt tctcaattag tcaatgacgg catcaacgat
    10141 tttcttaaat tctctgaaaa aaatagactc tgatcttgat gatgtgaatg acatactatc
    10201 ttcttctaga aaaattattt cctttaaatt atttattaaa tcaataatat gatcctcgta
    10261 agtatgcttt cccttggaat aatgaaaata tacttttgta ttacacaata ttgcaatttt
    10321 atttcttaat atgattattt cactcattca ttactgccac atatacacaa cttataacca
    10381 ccccctgcaa agtttagggt aagttatcag ataatatctt cctcttcatc atccagaata
    10441 caaaatctat ttatttatag aaatatcatt aatgttttta tataatgtac cgtgcttgta
    10501 ctcttgctct attacaagca ctaaaacact actattcatt tgaattctta cacggataaa
    10561 aatttacatc gtctatttca atattttttc tctctatttt attcacttaa taagttcatt
    10621 acataatcga aacatttttt attttccttg tcatcactcc ttgctccctt tttgatacag
    10681 atttaaaatt ctatcaaaga aatttccatc gttaaatttc gttattgcca aatccttcga
    10741 acaacgtgaa aattttacgt atttatcttt atcattgatt tttagtattg cagatgtcaa
    10801 cgctgatacg tcaccaggtt gaaacaaata tccattttct ccatcacgta ctgctgaaga
    10861 aatatctcct acatctgtag caattacagg cattccataa gaaatcgcct ctagaataga
    10921 tataggcaat ccctcgttat aggacggtaa aatcatcaca tttgatcttc tatagcactc
    10981 ctcctttttt tctcccacaa cccaacctgt aaattcaaaa tacgattgca aattatattc
    11041 ttctatcaat tctttgagcg atatttcttc atcacctgct ccagcaatct caaaaataaa
    11101 ctttttttct ggatattgtt ctgcaatgtt tttaactgct tctaccaaat cgtgtacacc
    11161 ttttcgcttt atcaaaactc ccataaacag aaatcggcac atttttgaat tccactttat
    11221 ggtatattct ggaactacaa tagaattttc tacaacaaca gttttacaat ttggctcaat
    11281 ttctttaatt atcttcttcc atttttctcc aagtacaatc gtggaatcag actctcttaa
    11341 cagcaagcga atctgatttt gtttttttac agaaacacta tcataccatt ttttaaattc
    11401 cgatccatga agatggatga ttacaggaat atttaataat ctaaaccact tattcagcac
    11461 atatttccta ctaaaactcc ctctgtacga catgtgcata tgaataatat taggtttact
    11521 caataaagag atacctataa ttttagcaaa tgcatacata aaatataaag atttaaatat
    11581 tgcatttcca cccttataac tcggtataaa agtcatctcg atattctttt tttcccaatt
    11641 aaaattgagc atttgtgtaa ttatacttgt aattccacct tttaccgagc tgtcattacc
    11701 aatcataagt actctttgca taacgcttta ctccttatat ttatattttt tctattaata
    11761 cctctatcga attaataatc gtttccgtgt tagatacata cttgttaaac atccgaactc
    11821 ttgtttcttt aacggcatct tctaaatttt ctaattcata acaaggatag ataatattca
    11881 tctcatcaaa ttgtctaatt aactgcagtt ggtgatcatc gacatgctca ccatacttag
    11941 ccaatcgagg aacagcaatg acccttttac ctttttttac ggccccaatt atagcacctg
    12001 tacctccatg agtaatcacc atttctgctt tttgcatagt ttcagtaaac tcatccctat
    12061 ttagaaatgc tttataggaa taatttagtg gtttataatc actataacca ctctgtgcaa
    12121 atgtactttc gattattact cctttttcaa ttaaatcatc aatagctttt aacaatctat
    12181 caaattgaaa tttttgtgaa cctaatgtta taaatatcat ttttttctcc tattatttaa
    12241 tatatcccac ccaaataaat atcattagga taaaattgta gcatagtttc ccactgaaca
    12301 taaaattgat ctgcaaaatg atacatcaat tttcctgtct gagtagggct ggttactttt
    12361 gcaaacgatt caatataaat cagttttttt cccatcattt ttgttattaa gcagataggg
    12421 atcatagcta aaacacctgt acaaatcacg agatccggtt tttcctttat atatataata
    12481 attgatttga ataaattaat aagtatagta cacaaaaaaa acttttcttt tctatttact
    12541 tgtctcatgt agtacgtttt ttcgcctttt gactcagctg aatattctgt ctgttctgtt
    12601 ataacaaaac tctcatactt ctccatcagt ggttttaaca tcattaactg ttcataatgc
    12661 cccccagagg aagccgcaaa acatatcttt ttgttcatat taacctctct atcagtcacg
    12721 ctgaaaaata tctctagtgt aaactttttc tttaatatca tccaagcagg tatcatatcg
    12781 attggcaata atagaatcac acatcgcctt aaactgctct aaatcgttga taaccttact
    12841 tccgaaaaaa gtctctccat ctttcagtgc aggctcataa atcaccacag tcgcaccttt
    12901 agcttttacg cgcttcataa ctccctggat tgaactctga cgaaaattat cactgttgct
    12961 cttcatggtc agccggtata taccgattaa aactggattt tccctgttga catcatactg
    13021 attatattca gcgtagttgt aatagcccgc catctgaaga acacgatctg cgatgaaatc
    13081 cttacgggta cgattagatt caacgatagc ctcaatcaaa tttccaggaa catctgcata
    13141 gtttgccaac aactgcttgg tatcttttgg caagcaataa cctccatatc caaaggatgg
    13201 attgttgtag tgagttccaa tacgaggatc gagacaaaca ccattgatta tctgctgagt
    13261 attcagcccc ttcatttcag cataagtgtc taattcattg aaatagctga ctcgcagtgc
    13321 taaataggta tttgcaaaca gctttactgc ttcggcttca gtgaatccca taaaaagagt
    13381 atccacgttc tccttaattg cacttttctg cagaagtgtt gcaaaaacat gagcagcatt
    13441 taacaagcgc tcatcagtca tatcagtacc aacaataata cgagatggat acagattatc
    13501 atataaagcc ttgctctcgc gcagaaactc tggactaaaa ataatgttct tactccccgt
    13561 tgtctcacgg actgattcag tgtagccaac aggaattgta gacttgatga ccatgatggt
    13621 atcaggattc acgtccatca caacctcaat aactgactca acagcagaag tatcgaaatg
    13681 ctgagtacga ctgtcatagt tagtcggtgt agcaataaca acgaaatctg cggatttata
    13741 agcgctcctt gcatccaaag tagcagttaa gtcaagttct ttttctgtaa gatacttttc
    13801 aatatattca tcctgaattg gagacttccg tttattaatc agttcaatct tttcagggat
    13861 aatgtctacc gcggttacct ggtgatgctg cgccaatagt gtggcgatac tcaaaccaac
    13921 ataaccggtg ccggctactg cgatgttgta ctttttcttc acaatatctc ctctttcctc
    13981 tcttaagtat ggagaatgtt actcctacgg ctattcatca tgtcaaaata acacagctta
    14041 gaatgttgat aaaataattt tccagaatgt gataaaatct ctttcattta taaaccacac
    14101 atctaatttt atctattctc cacaagacat gtagagtatt ctttaataac aagatacgac
    14161 cttactaaat acttcaaaaa attatcatat ttaattcata aatataaatc ttcattttaa
    14221 atgtatgccc aaaaatttat ctgtaatgcg tcatcaaaat ctagattcca aatctttatc
    14281 aatttttatc cactcattct accactttag taatattttc tatttataac actttcgtcc
    14341 tacattgatc cccccctctg aagtacagtt tttactgtct taaataaaat tttaaaatct
    14401 aaccccatac tccaattttt tatatattcc gtgtcaagtt ttgctacttc ttcaaaatca
    14461 gtaatatcac ttctaccact tacctgccac attccagtaa ttcctggctt gatagcaatt
    14521 cttgcacgat gatgataatc atattcttca tactctgatt taaggcatgg tcgaaatcct
    14581 ataaggctca tctttcctgt tagaacgttg aaaaattgag ggaattcatc taaagacgtg
    14641 gatctaataa attgaccgat tcctgtcttt tttgttccat ctggaagtat tttatttccg
    14701 ataattcttg gatcaaactc catcttaaac ataagattat tgctcatctt attttctttc
    14761 attaattcta cttttctttc ttctgcatcc atatacatac ttctaaactt atacatcttg
    14821 aacggtttac cattctgacc tatacgttct tgtgcaaaga aaattgggcc tggtgaatta
    14881 atataaataa gtggagcaat aaagataaaa ataattcccg ttgcaataca tccaacaata
    14941 cctgcaagaa tatcaattgt tcgttttata aatgcctgtt gagttgtcat aacattgata
    15001 cttgttgtaa gtactgtata ttctcctata cgaccaatag attgttttcc caaagcacta
    15061 tctgatactt ttgcaagatt caaatgtaca gtaaggccca tttcagagca tcgttcaata
    15121 aattctttca tacacgaagt acttttattc aaaataataa agacttcatc tacccatccc
    15181 tgacataagt aatccgctgc atttttggaa tcagaaacaa ctgtcactcc ctcaacatct
    15241 tcaccaatca tgcttttatc tatgataatg acaccattta ttttatacat tttatagtta
    15301 tgctctttca cattacgaat aactacttca gcaatactac tagatgtaac tataataagt
    15361 gatttgttcc cctcattttt cattttatgt ttcaagtaat gtttccataa gaggcgagtt
    15421 atatatgtaa ttacaacgta taaacctccc atcaagaaaa gaacgactct agaataatca
    15481 tttccaccct gaacactaat gagatacaaa cttcctaaca gcaccaacat aatcgcttgc
    15541 tttacagaag aagcaaattc tatatagtac cctcttttta atacacctct atatgcttca
    15601 aacatgaaaa taactaaaag atctgccagt tcaatgaaga ctgccatgtt ttgatacatt
    15661 ggaatcacat aaggattcca atctacctgg cgtaagacat acgatagata aaaagcaagc
    15721 tggatacaca ataaatctaa aataataaaa tcaatatgtt taacccatcc ccttgaactt
    15781 ttcttgtaca ttccttttta ctcccccctc tttttaataa aataaattgt attacttgtt
    15841 ttctctccta aatatctttc tgaaggatta ttgactcgac aaattggctt gtggatattc
    15901 ttatatatag aacatccgta agccaactta aaactcctta acaaaatttt tttactcata
    15961 ttgtagatca aaacaagtat ccaagaaatc atattttatt tcttttttct gcttactcaa
    16021 caacagctaa aagaaaaatc atcataaaca aattcaacta agccaacgat ccccttgtga
    16081 aatcaagttt tttcttgatt tacgaataaa gagctaaaat aaaccaaact tcttcttttt
    16141 tacctcttca tagactggat aactgatttc atccccgttg atcagatcct ttgcgacttg
    16201 tttcatctgt actacttttt ccttaccaaa gtcctttgca atctgctcat agcactcttt
    16261 taagtaaaag gtgcgcttag agaccccatg ggcatcagaa gcagccatct gcacgagatt
    16321 atgtttgacc atcgttttgg ctgttttctg gatgtctttg ccaaataccc caacataact
    16381 tggcgcagtg agttgggcca aacatcccat atctaggaac ggaagcaaat gatttgggtc
    16441 ttcgcgaaaa tgcacgttgc gttctggatg gacgattact ggtgtctttc ctagttctaa
    16501 caactcaaaa aaaagccgtt ctgcatataa cggcacttcc agtgtcggaa attcgatcag
    16561 aagatatgta tcatctaaat ctgtaaataa tatttcatct cggtggatgt cttcgatgag
    16621 cgttccggta atacgtactt cttgtccttc caataacgtc aaaggcaact gtcttttctc
    16681 taattcggct tgtaacgaag cgactagaga aatgacttgt gatttttcat tgctgtattt
    16741 tccattattg tggtgtggtg tgcataaaat atgcgtgatg ccttgctgaa tcgctttttc
    16801 agccattgca atacttgctt ctaagttttc tgccccgtca tcgattcctg gtaggatatg
    16861 gcaatgtaga tcgatcattt ctcttgtctc ctctcttctt attccttaat ttccgtagta
    16921 ataaccagca tctttgctat gttctgctcc gttgtacaca acacctaaga ctcgtgcttg
    16981 taccatctcc agcagttctt ttgctttagt caaggattct ttacgtgaca tattttcacg
    17041 tacgaccaat aaagtgccat ccgtttttaa agacatgatc tgtgcatctg ttacggctac
    17101 tactggtggc atatcgaata tcaccacgtc aaataactgt cttgcttcgg ataggatctg
    17161 atccattctt ggcgagctta acaattctga tgggttgggt ggcttaggtc cactaggcaa
    17221 aatcgacaag ttctcgactg gcgttcgttg gatcacatct gctacacttc ctgatgaact
    17281 aagtgctgta cttaatccac tggcattgtt cagctggaat gtcttataga cgacgggttt
    17341 acgtaaatct gcatcgacta gtagaactcg ttgacctgat ttagcaaaaa cgactgcaat
    17401 gtttgctgca gtggtggatt tcccttctcc aggacctgat gaagtcacga caatcgtttt
    17461 gatttgctga ccagctgcgg aggcaaactg gatattcgtc cggatcgtac gatattgttc
    17521 ggcgattggt gaagatgggt ttgttaatgt gatcaaactg actgcatgag tttgtgctgc
    17581 tttttgtttc tgtgttcgtg ccatttttct tcctcctaga ctcttgagcg gcttctgcgt
    17641 gatggggctg ttttatcgtt tgtagctttt ggtcgtgcag gagctgttcc ttttttacgg
    17701 ataccagcgt tcaattcttt cgctgacatt tctggaactg ttcctaagat tgggaatcct
    17761 aatgtatctg tcacatattt ttcatctttc actgtccgat cgagtaattc caataagaat
    17821 gccagaccta cacctaccat cattcctaac attaagccag tcattaaatt caatttatta
    17881 tttggcgaaa caggtgtcgt attggcaact gcacctgaaa tgatcgagat tttatcaaca
    17941 ttcatcacat cttttgcgtt ctcttggaaa acttgtgaag ttgtgttagc gatctgttga
    18001 gcagccactg cattcgtact tattgcctga atcgagaaca tttgtgaatt ttctgcctga
    18061 ttaactgaga tggcatcttt gatttgttca gcagtcattt tcacattgtc ttctgtttct
    18121 aaacgatctt tgacttcatt gagcactaaa tcactgacga tcatatcttt atacgtattg
    18181 atcatttgca ggttcgtatt gacatcattg acatttgcag tgtctgattg tggcagtgtc
    18241 acgatcaatt gtgcttgtga actgtatttt ggtgtcaaga tgaaaaatgt tacgattcct
    18301 gagatggcca agccagcaaa cattgagatg atgattatta ccaagtgttt gcgtaatgtt
    18361 tcaaaaattt ctttcaagct gattgtctct tccatttttt ctccactttc ctatttattc
    18421 tctagattca tttgatcttt taattctttt ttcacacgat caagttcttg atcactgact
    18481 ttttgatagg agatattatc ttgcatgaag ccttctcctt gcagctgatc ttgcttaatc
    18541 gtaccaaatg cctcccgata atctaaagca atttttttca tttcatcaaa gttcatgtct
    18601 gttttcatat tcgactctag agcattcaaa acggattgat agttgctgac accgtttaga
    18661 ctcaatactt ttttcgctac gccttctacg atctttcttt ggcgcccttg tctaccgtaa
    18721 tcaccatttg ggtcttcata acgcatacga gaataagata atgcctgatc cccgttcaat
    18781 gtaattttac cgattggaaa gtcatagcca tcttgtgaga aagtgaggtc attattgact
    18841 tcgataccac caactgcatc aacgagttcc tttagtcctt tcatattgat agagacatag
    18901 tgatcgattg ggatgtctac atatttttgt acggtatcca tcgccatggc agctccgccg
    18961 aatgcgtaag cgtggttgat cttgtctttt gtgtcacgac ctacgatgtc gacatacgta
    19021 tctcgaggaa tgctgacgat cgttgtctgt ttgtcttcag gactgactgt ggcaaccatc
    19081 atcgtatctg atcttccttg atcgacccga cctaaatctc cagtatcaat ccccatcaat
    19141 agaacagaga aagattcttg tttgtccaga tcaactggtt tcgttcgttc tccttgggtt
    19201 cgttccactg attcgtaagt tttctcaata gaatgtgaga gatccagata taattttgct
    19261 cctactccta caattgctaa tactaatacg ataagaactg ctaaaataat caaaaatatt
    19321 tttttccctc ttgattttct tcttcgtctt gccatagttt cctccgtttg ctaaccttgc
    19381 ttgaatcaac gttttaactg tcaatagctt atattgctat agcccatttg ctgagcaaca
    19441 gtttgtgctt ttgttgcgta tgcggctctt attttttcat tccggatctg ctctatttga
    19501 ctgagcgccg tcaaatattg atcgtaagta gcggtagctg ttacttgacc gtctttcagc
    19561 atcgtatcga atagctgatc tagttgcgtg acttgtgcaa tttgggtatc agcgaatcct
    19621 agatattgca taacgactgt tttccaagca ctatccttaa aaaagctcat attttcacgt
    19681 acatgggcga catctgcact tgccaacttt tctttgatga tgacatcatc cacagcttgc
    19741 tgccagtttg atacgttttt agtaaataat ttattgacag ccgtctggat cttcagtttt
    19801 gattctgcat cctctaactg cgttaagact gctttctttt cttcttggat cgcagcagct
    19861 tctttaggta attctgattc cttgatgtca taatcatctg ccgaaagttt gatagaagat
    19921 agtttatgtg acaaatttga aactgtttct tctgttattt caggatttag gaaaattttt
    19981 tcttttgtac tgtacagctt atctacttct tttgataaag aggtcacggt gtctttttga
    20041 ttggtgatgg cagattctgc gtaattgatc cgttgatgat attgccgctg attattgaga
    20101 tggtatccaa acaagcaaat cacaatagcg cctgtgccta ccgccacagt agccaataac
    20161 ttgacgaacg gcttttccat agattcactc ctaaatattg atgatagata agtaaagatg
    20221 tgattcattc acatcagaat gagcgctttt tattttaaaa gcataattaa actaatatat
    20281 tcatagaaat atttataaac aggttttccc tatataatca taccacatac agtttttttg
    20341 actagggaaa ttcctaattt aaaagtaaat aaaacagtaa caagattata attaatcgtt
    20401 ttcattttta tttcctcact tttcatgagc gttttgaaaa ttcgaacaaa gaataaaata
    20461 acaaaaatta ttaaaataga attaataaca gctatttata acaaaaaaaa cagagacaca
    20521 gcacgtttcg tgcatgctct ctgtttttca aacaaaagac tattttgtga tgatttgatc
    20581 caagcttgct aatgacaaag ccatggcagc tatttgactt agttgtgtta gtcggttctt
    20641 acgtactgct ggttcatcag ccatgaccat cgtttgatca aaataatttt cgatcagtgg
    20701 acgaagagcg acaagctggt cgtagttttc gtggatcgtt tggtcagcaa aacttgcttt
    20761 cattgcttct actgctttgt gtaattcttt ctctgcgtcg ttttcgaaca gctcagggtc
    20821 tacttctgat tgtttttcaa gctgcgcttt tttcgctaag ttcacgacac gtgtcaaagc
    20881 ttccattgaa ggtttgaagt cttcatctgc aagatgttgt ttgaacaatt gtgctgctgc
    20941 aaatactttt gtcagatctt tttgttccgc attcaaaaca gcatcgatga catcatgacg
    21001 aatattcttc gttgtcaata attggcgcag acggcctttg ataaagtcga tcacttgttg
    21061 ttgcccttct gataaaccaa tgccgaaacg atccgtatct ttactgataa catcgctaat
    21121 cgtttcttgc agaacagaca aaggaaaggc ccattttttc gattcgatga tccgaacgac
    21181 accgtatgct tggcgacgta aggcataagg atcgtttgac ccgcttggaa tcatcccaac
    21241 tgcaaagaaa gaaaagatgc tatctaattt atctgcaatc gctaaaacag aacctactgt
    21301 agactgaggt agctctcctt cactggatat aggcatgtaa tgctcacgaa tcgctgtcgc
    21361 tacagcaggt ttctcgcctt tcagaagagc atatttttcg cccatgatcc cttgtagttc
    21421 aggaaattcc cctaccatgt tggttactag atcaaattta tagatttcag cagctcgttg
    21481 caaatccatc aattcttcct cagatagtcc tacttgttcg ccaatgatac gggcaatgac
    21541 ttgtacccgt tgcattttct catagatact accgattttt tcatggaaag taacagtttt
    21601 tagtttttca acgtattggt cgattgaagc tttcttgtct tcattataaa agaattccgc
    21661 atcttctaaa cgagccgtca atactttttg attgcctcga accacatctt ccaattttac
    21721 ccgatcacca ttacgagcag aaataaaatg aggaagcagc ataccttgat cattccgtac
    21781 ctcgaaataa cgttgatgtt ctttcataga agtgactagt acttcttcag gaacagaaag
    21841 atatttttct tcgaagtcgc cagaaaagac agttggatat tcgactaaat tgttgacttc
    21901 ttctagtaaa tcttcgtcta gatcaataac ccagtgattt ttttctgcta attcgtttgc
    21961 ttgtgtaacg atcatttctt gtcttttttg cggagacgca atgacgaatt gttcattcaa
    22021 tttttcttca tattcttttg catgcgcaaa tgtcacatct tcgcctaaga aacgatgacc
    22081 tcgagaggct ctgcctgttt tgacatccaa gatttcgaat gggattactt cgtcatctaa
    22141 caatgccacg atccagtgaa tagggcggat atattcaaaa tcgtattctg cccaatgcat
    22201 cgttacaggg aaagtcaaac ttttgatcac ccctgctaag cctgtcaata cttcttttgc
    22261 ttccttacca tgagtgtatt tcgttacata gacatattcc acacctttta attctctaaa
    22321 agtgatagcg tctgtcgtca gaccttgtcc gcggacaaat ccttccgctg ctttcgtcca
    22381 gtttccatct gcgtccaaag caattttttt ggctggtcct ttgacttctt cttcactgtc
    22441 cgcttgtcgt tctggaatat ttgttacttt gattgctaaa cggcgcggtg tggaaaatgt
    22501 ttcgatcgta tcataagtca attggttttc atctaaaaat tttgctgttt tttcttctaa
    22561 ttgtttcatg cttggtgtga caacatgggc aggcatttct tccagcccga tttcaagtaa
    22621 taagtctttt gccatcttat tcagcctcct tcacggtttc tggatttgct gtgtttttat
    22681 tcaacaaagg gaatcctaat ttttcgcgtt ctgccacaaa gattttggct acagcacgag
    22741 ccatgttgcg gatgcgagaa agataaccgg cacgctctgt tacggatact gcaccgcggg
    22801 cgtctaataa gttgaatgta tggctacatt tcaagatata atcatacgcc ggatgaacaa
    22861 gattttcatc gatacagcgt ttagcttctt tttcaaaacg atcaaagttg cttagtagca
    22921 agtcttggtc gcttacttca aaagaatatt tggaatgttc atattctggt tgtttgaaga
    22981 tctcgccata tttcacgcca tcagcccatt ctaaatcata gacactttca acttcttgga
    23041 tataagaagc aagacgttct aatccataag tgatctcaga agttactggt ttacaaggca
    23101 gtccaccaac ttgctggaag tacgtgaatt gtgtgatttc cattccgtca agccatactt
    23161 cccaacccac accggcacag cccatggatg ggttctccca gttgtcttca acaaaacgga
    23221 tgtcgtgttc taatggatcg attcctaaaa ggcgcaagct ttctaaataa agctcttgaa
    23281 tattctcagg tgaaggtttc atcaccactt ggaattgatg atgctgatac aaacggtttg
    23341 ggttttcacc ataacgtcca tcagctggtc ggcgagatgg ctctacgtaa gcagcattcc
    23401 atggttctgg tccgattgcc cgtaaaaagg tatatgggct catcgtacct gctccttttt
    23461 ctgtgtcata agcttgcatc agcatgcagc cgtttgatga ccaaaatttt tgtaatgtta
    23521 aaatcatatc ttggacggtc aattttttac tcatctgttt tgcccctttc aattttaaag
    23581 cgttgctgtc aaataagaat acaggaaaga aaacgacaaa aaatccctat gtctgattac
    23641 agacataggg acgaataatt cgcggttcca ccctacttcc gaataaagat tcggcagctt
    23701 catttatcgt actcgcaagt gcctcttcaa aaatcgtttg ggtccggctc ccactctccc
    23761 gaactcgcta aaccacgtgt tttttactga tcttggtcaa tgtacgtatt cattttgcag
    23821 ttttcttgtt tctataatag atcctatcac tgaacgatct atttaatcta tggttaataa
    23881 tagacggaac tccctgtgtt tgtcaaatgg ttttgatttt ttgttgtatg ttttatttac
    23941 tattcttctt tttcaggtgt ctctttttct ttttcagaca tgtctttctc tgacgtcttt
    24001 aatacgtgtg cccaagactt catttgattg atgaactttt tgcttttcaa atggataccg
    24061 acatattcat catacagctg gtcgatgagt tcacggattg cttgtttggt ttcttctttc
    24121 agatggattc cactaatttt atcataagaa atagctgaaa acatccgaac gaaataaaca
    24181 gctcgaggat ctgcatgata acggtgatcg tccatcgacc aatgtctttc gcatatcaca
    24241 ccaccatatt tggaagaata gtcaaatttt ccttttgttt ccccgcatac gacgcagtgt
    24301 gtccagattg gtgcaattcc gaagcgttgc agtatttgga cttcaaaaat attcgtgatg
    24361 atttctgcat cgtctccttg gtccatccgt tgcagtgctt gttgcgtaaa ctggaacaaa
    24421 tgcgggtcgt actgatgatc ttcgattgcc gcatctacta gattcaataa atatgtgcca
    24481 tagccgctca aaaagatgtc ttcttggatg tgtcgaaacg catggacatc tttgacactg
    24541 cttaaaaatg acaaaccttc acttcgaaaa ttcccgatat aaactgcttc agtaaaaggg
    24601 agcaaagccg gagctaaggg ctgattttgc cgatggatct ctttgatata aaacatcatt
    24661 ttgccagaag attctgtaaa gattttgact aatttatctt tttctttgta attacggcta
    24721 gataaaatca agccttttga ttctgcaagc tggctcatat tctccctcct aaaaaataaa
    24781 tctggaaaag cagattctgc cgatccagat catttatgtt gcgatcttcc gcagcttttc
    24841 tcaacacgcg gatttttatt cagtttattt ctatacctaa tttacaagaa gctcagaata
    24901 tcagtattcg tcttttcggt agccgaagtc ttgcagatag acttttttgt ctcgccagtc
    24961 tttttgaact ttgacccaaa gttctagaaa gactttgtct cctaaaagat tttcgatatc
    25021 ttttcttgct ttcgttccta cttgcttcag catttttccg cctttgccga taatgatccc
    25081 tttttggcta tctctttcga caataatcgt agcctggata tggattttat cattctcgtt
    25141 tcgcttcatc gaatcaacaa cgactgcgac agaatgaggc acttcgtctc gtgttaaaaa
    25201 caagactttc tcacggatca attcagaaac gatgaagtat tcaggatgat cagtcacttg
    25261 atcatctgga aaatattgtg ggccctctgg catttcactg actaatacat ccatcaaacg
    25321 ttcgacgttg tttccttctg tagcagagat tggaatcact tgtgcaaaag gcatctgcgt
    25381 tgaataatct tcgatgattc ccaacaactc gtctggatgg attttgtcga ttttattgat
    25441 aatcagataa acaggagaat gcacgttttt tagacgttca ataataaaat cgtctccccg
    25501 accgcgtttt tgatcagcac taatcataaa taagaccgcg tccacttctt tcaacgcact
    25561 gtaagctgct tctaccataa aatctcctaa acgatgcttt ggtttatgga ttcctggtgt
    25621 atcaataaaa atcaactgag cttctggtgt agtgtatact ccttggattt tatttctagt
    25681 tgtctgtgcc ttgtcactca tgatggcaat tttttgaccc acgattcgat tcaataatgt
    25741 ggatttccct acatttgggc ggccgacgat tgcgacaaac cctgatttat gttctggcat
    25801 atatgttctc ctttttaatt aaacaacaaa tgatatattt tagggacaaa taaaatcaac
    25861 ccaacgatga cggtaaaaca agcggtcact aaaactgctc cagctgccat atctttgatt
    25921 tttttcccaa tcggatgaaa atgaaaatcc gtaaacatgt ccacgacatt ttcaaaaaca
    25981 gtattgatga tctctactat ccatacgaga aaaacagcta aaagcagcca taaccattct
    26041 atccgatcaa gttggaaaat cacgcccata aacaaagcga ggattccgaa cgcaacatgt
    26101 ttcctcatgt tgcgttcttc ctcaaaaaca gttttgactc cttggacggc aaattccacg
    26161 gacatcagga aatgtttgtt tttctctacg tttttatctt ttaagtccat aggcatctaa
    26221 gatctctttc tgtaaaccaa acatttcttt ctcatcctct ggtgtcatat ggtcataccc
    26281 gttgatatgc aagaatccat gaaccgctaa aaagccaagt tcccgatcat acgaatggcc
    26341 gtaagcttct gcttgctctg cagcacgttc agtagagatc atgatgtctc ccagtacacg
    26401 aggcaatgga ttctctccat cttcaaaaat cactgggatt tcgtcttcgc cctcttcttc
    26461 caaggcaaaa ctgatgacgt ctgtcggtgc atcttttcca cggtaatcac gattgattac
    26521 ttggattgct gcattgtcca tgaaagtaac agacatttct gtttcttctg gcaactctaa
    26581 atatgatgct gcaaattgca gcaagtcgtc gatttctttc attttctctt ctgagacttg
    26641 gtttgtttca tccatgaagg taatatccat tatacatcgc ttctttctat tcttcttgct
    26701 attcttcttg ttcttctttt atcttctcaa cttccgattt cattttagga tatttgatcc
    26761 gagaatggaa ggtactgctt aaaccgctga tcaatgattt ttctacttta cggatttctt
    26821 ttaacgtcaa tccactgtcg tccaattgtc catcggaaat acgctcttca ataagattat
    26881 ggacaaaact ttcgattttt tcgctcgttg gatggtccat tgcccgtact gccgcttcac
    26941 aactgtcagc tatattgacg attcctgctt cacggctttg aggttttggt ccaggataac
    27001 ggaattgctc ttccgtaact tccgggttgc gttcctttgc cttaacgtag aaataacgca
    27061 tcagcgtggt tccatgatgc tgtctacaaa tatcgatcac catttgcggc atattataat
    27121 cttccaatat tttggcacca tctgtcacat gtccaaagat aatatgttta ctgtcttctg
    27181 gcaataagaa attgtgcgga ttttccgctc ctgaaggcaa gttctcaacg aaaaagctgg
    27241 cgtgtttgat cttgccgata tcatgataat agcaagctac tcgagttagt aaagaacgtc
    27301 caccgatttc tgctacagca ttagcactta gattggctac catcatgcta tggtgatacg
    27361 tacctggtgc ttcttccagc aactgtttca ataaaggatg attgggattg ctgagttcat
    27421 ttaatacgat cacactatca tcattgacca tcaattcaat ataggggtgc agacctatcg
    27481 tcagcaagaa tgaaaacagt gcacctgtga atccgcagac tagcgttaac caagtcgttg
    27541 catccccaaa gctcattcct tggtagataa tcaaaatgac atccatcatc acaggaaaaa
    27601 taatgaccca catagcagcg gataaccctt gttctgagat ccgtttgcgt ctgacgatcg
    27661 ttgccatgag accagaaaat acataggaca tcaaaataac tgtcagaaag ttcgtgccaa
    27721 tcgaatcata aaaaatgaaa agtgcggata ctgcttgaaa aataccagcc atgatccctg
    27781 ctcttcgatt caagaaaaag cttaaaacaa gtggagcaaa agccgcgggg taaaacagcg
    27841 gaatataagc agcttgttct gtttggaaga gttggaaaaa tttcattagt acgacgctta
    27901 ctgacattgc cgtcacgtag aaaagtacgt attttgttct ttctcctgca ttttggaatt
    27961 gaagtgaatt ataaatcagt acaccgattt gaagcaaaac agctaaaacc atggcaatga
    28021 gtgggaaaat agaagtcgtt tgattcgtca atcctagtaa ttccaatttt ttcatcgctg
    28081 aagcatcaat ttgatttcct tcgcgaacaa taatttctcc ttggaagatc atcactggtt
    28141 gtacagcttc tcgtgcagat tgttttaatt cttctgtctt tttctcattc aatacatcat
    28201 taactacgat gccttgatcc actaagtagc gaatcatttg ttgctgctct gttgtgacat
    28261 tcaaatattg aatctgatct tctgcttctt gtttaaaagc ttccaattcg ctttcacgaa
    28321 cttgtttact catctgttcg tcaatgagct tcaaactttc atccctaact gtgtgaattt
    28381 ccgtttcagt catttcaaat atcgtcgaat aaaaattgtt cggcagtttt tggtaaaacg
    28441 caacgttttc tgcattcacg ttttcaaaat ttttcttcag tgtagcaatc cgctcttctg
    28501 tagtaggttt cgggatattt tcatcttcct tcgccttatc taccttgcca ttataagatt
    28561 tgttgatggt atcattcgtc ttatcgatca attcgaataa ttgcttgatc cgattgttct
    28621 ggtcatctgc cagatctttt tgataagtat attctggagt cactgcttct gctgccagtt
    28681 ttcttctttg ttcggtttct tccgtgttct caatcgtttt attcgcacgg atactctctt
    28741 ctgctacttg gccttctctg aaatcaatgg ccttttgttt gacactacta aatgtaacgc
    28801 cgcagacaat gataaaaaac aagaacagaa ggaaaggcaa tgctgccttt ccgagttttt
    28861 cttgtagttt ctgcagtgtt ttattcaaca tgtgcttatc ctcctaagca aagcttattc
    28921 ttgatgaaga tccgcctttt cataagcttt gatgatttcg gcaactacag ggtgccgaac
    28981 aacgtcactt gcttcaaaat taacaaaatc gatttttttg atttgcttta atgttcgttc
    29041 tgcatgaaca agaccacttg tcgtcccacg aggcaagtct atctgacttg tatccccatt
    29101 gacaatcatt tttgattgat aaccgagacg ggtcaagaac attttcatct gagcgactgt
    29161 cgtgttttgt gcttcgtcca agataacgaa tgcatcatcc aatgtccgcc cccgcatgta
    29221 agctaaaggt gcgatttcga tcacgcctcg ttccatcaat cggttcgtat gatccaatcc
    29281 aaaaatttgg tataaagcat cataaacagg ccgcagataa ggatccactt tttctttcag
    29341 atccccgggt agaaagccta ggttttcccc tgcctccaca gcgggccgcg tcaaaatgat
    29401 tttttgcact tcgccttttt ttagggcagc aattgctaat actacggcaa gaaacgtttt
    29461 ccctgttccg gctggcccta caccaaatac gatgtcatgt ttggctaccg attcaacgta
    29521 tttcttttga ccgctgtttt ttacccgtat aggttttcca ttacggtctt tgacgatctc
    29581 ttcctcatac atctcaacaa aataatctaa tgtacctttt tgccccattt tcaatgccgt
    29641 cacaacatct ggcgtactta cgtggattcc tcgtttgatc aattcctgta atgtccgaat
    29701 gactgaggca gccaaggaaa tctgggattg ctcaccaatg atctgaatga tttctccacg
    29761 tgtatggatg gttgtttccg ttgtttcctc gatcagtttt atatgcttgt cgtgtgcacc
    29821 taaaagcatg ctgacatcat cagcagctgt caatctaatc tctaaagaac tagactcttc
    29881 cgtcaaaaat agacatcccc tttttttcga ttcattcttt cctattttac catactcaga
    29941 agaaactata tagcaaataa gaaaaggttg taaaagagtc gcttaaccat acgtaccaag
    30001 aaacgttaaa aaatagccgt ttccattcgc taaaggtctc gttttgataa aaagaagctg
    30061 agaatgtaag ttatatgaaa gtggagaaca aaatatttcg tttcattcaa caagtattct
    30121 ctaggtattt ttcctgtttc aaaaaaagaa aacaaaatag ttaaaatatt cttgcatttc
    30181 aaaaaaaaca ggtgtattat tacgtcaaca aataaacata cagcaaagcg tcgaggaaaa
    30241 cagtaggcta ttcaacgatt tattcccagt gagtcatgta agtgagaaat gacaataaat
    30301 cgaatagacg aacatcattt ccgagtcaat gtcgaaaacg tagatcattg tggctgcctc
    30361 cattatcagg ctagcggata actttatcaa aaagcgtccg tgaatgaaga agctttttta
    30421 agcgaaaaaa ggtggtaccg ttctagaatc tagagccctt ttcccaagtg gaaaagggct
    30481 tttttttatt ttaaggtggt ggttttcatg gaatctgata ttagtggcat tactaattgc
    30541 tgcaacgttt atatcgtcaa tcaaaatgat aattattgga ggaaaaattt atggaagaaa
    30601 caaaaactta ttcatggaaa caactattga tggtcagttc acttatcttc gggatgttct
    30661 tcgggtcagg taatctaatc tttcctgtcc acttaggtca aatggctggc gcaaactggg
    30721 tcagtgctgg cgtaggattt gctatctcag gtgctctttt cccattacta gctatcttag
    30781 ctgtagtagt gacaaaaagt gatggtctgt atgacttagc taaacctgtc ggaaaatggt
    30841 atgctgcctt gttcttaatc cttgttcatt tgacgatcgg accatttttc ggtacaccac
    30901 ggacagctgc tactgctttt gaaatggctg ctaaaccatt tttgcctgaa aaatataatt
    30961 cattaggtat gtttttattc tctgctcttt tctttttact tgcttatttc cttactgtcc
    31021 atccaacacg gttggtcaaa tacgtcggaa agtatctaaa ctccttgttt cttgcattat
    31081 tagcaatcat ttttgtcgtt tctttattcc atccaatggg aaatctaaat caatctgctg
    31141 cagatactta tcaaacaaac gctttaacaa atggtgtcct agaaggttat aacacggttg
    31201 atgcagtagc tttgcttgcc ttaagtgtca cttttgtcca tgcagtccgt gaccttggtt
    31261 tcaaagataa aaaagtcaca gaattaacgg caaaagctgg tagcctgagc gttgcgctag
    31321 aagtcatgat ctattttgga cttgttcttc tcggtgcgat gagtttgaat aagatgtctt
    31381 tatcagaaaa tggcggaact gcactttctc agatcactaa tttttattta ggtaacttcg
    31441 gcgctagctt cttaggagtg atggtcacat taggtgtctt cactaccgct atgggactcg
    31501 ttgtttcttt tgcgcaagat ttccataaac tgttccctaa agtcagttat atgacatggc
    31561 tgcggttaac gactttcgtc tcttttgtcg ttgcaaatgc tggtttagac aatatcatcc
    31621 aatggtcttt accagtattg atgcttttgt atccattgtc gcttgcgttg atcttgcttt
    31681 ccttaacagc aaaatttttc caaaagacac catttgtcta tcaagtaacg atgttgtttg
    31741 ctgctgttcc tgccgtattg gatatgctgg caaattcgcc tgctttagtg agtcaacaaa
    31801 gagttgtagc aagcatgctc gaattttatc atcatcacgt tccttttgct gcattaggac
    31861 ttggctggat ggtcccaacg ttacttggtt acgctggcag cctactgttt tattacgcct
    31921 atcgcctatc agggtataaa caagaagcaa atgaactacc agaagaataa ccaaatcaaa
    31981 cacaatttaa cataagaaat attaaacagg aaaaaaccag ctagatgaaa gaatcctatt
    32041 ctttcgtcta gctatttttt agttctcttt tttacgcgca caaaaaaact gcggacaatg
    32101 attgtccgca gtttaaatga taaaattaag attgtaatag ttctttcaca atggcattta
    32161 cttggtttcc atctgctttt cctttgactt taggcatgat cgcacccatg actttgccaa
    32221 attctttcat tgatgaagca ccagtttgtg tgattgcttc ttgaacaagt tgtcgaattt
    32281 cttcgtcgga aagttgttcc ggcatgtatt tttcgactat cacaatttca ctttttactt
    32341 tttcagctaa atcgtcacgt cctgcttctt caaactcatg caaagaatca cgtcgctgtt
    32401 tcatttcgcg agacaacacc gttaattctt cttcttctgt caagtcgtga ccttctttaa
    32461 tctgctcgtt ttgtatagat gacttgatca ttcggatgac ttgtaaagat tccttatctt
    32521 tcgctttcat cgctgttttc atgtcatcgt ttaatctact tagtagtgac acactaccaa
    32581 ctccaattca tcacagaact agaatttttt gcgttttcta gctgcttcag attttttctt
    32641 gcgtcttaca cttggttttt cgtagaattc acgtttacga gattcttgta aagtacccgc
    32701 ttttgacacg gaacgtttga agcgacgaag agcatcgtca agtgattcgt ttttgcgaac
    32761 gactgttttt gacatgttaa ttccctccct ccgagcttaa aaagtaaccg taattgttat
    32821 tgaaatatat ctcaaaaaac aagactgtcc tgtaaatatt atatctaatg ctgttttgac
    32881 cgtcaaggaa atcttgcttt tttttaaaat tatcaaatgt tattttattt aaatccttat
    32941 tgacaatttt cacatcttcc gaaaatctcg aatctatgcc cttcgatcgt acatccaccg
    33001 agctgttctt cgaaataatt cattggacac atatggattt ctttcgttgt tccgcacacc
    33061 gtacagataa agtgatggtg atggccgatt tccccttgac agcaatgaaa acgaaacttc
    33121 atctctccat ttaaatcggt ttcttccagt aaatcgattt ctgcaaaatc atggagattt
    33181 cgataaatcg tatcgtaact tactcctttg aattcctgat tcatatagtc aaaaacttct
    33241 ttagcggata cgtagcgatt gcgcttcact aaataagtta acaatgcttc tcttttttta
    33301 gtatatttaa aaccgttatt tttcaatgtt tctagtgatt gttcaatcaa tgtctgtttt
    33361 ttcatgactt attcctccaa atcaaaatga ttacgaagta cacattctag agtatggtat
    33421 aataaacata aaaaaaatgc aagtgaggtt ttatccatgt cttccgattc tacagaaatc
    33481 attacttttt ttgtcatctc tgactctgct ggagaaactg cgacaaaatt agcgcaagcc
    33541 actatggccc aatatcctac cgttgagttc aatttattcc gcagaacatt tgtgacagat
    33601 gagaaaacat tgatgcaggc actgcaagat gcactaaaag aaaaagccct tgtcctacac
    33661 acattgatca atcaagaatt gatcgagatg acgcgttctt tttgtgaaga acatcaatta
    33721 tttagttttg atgtgatgac tccgccgata tcagaaatcg agcgcttaac tggtatcaag
    33781 cccattcggc aacctggcgc ccttcattta ttgaatgaga actatttcaa acggatcaaa
    33841 gcaatggaat ttgctgtaaa atacgatgac gggaaagatc ctcgtgggtt tctagaagca
    33901 gatgtcgttt tgctaggcgt atccagaact tccaaaacgc ctttgagctt gtttttagct
    33961 aacaaaaatt taaaggttgc caatctacct ttgatcccac aagcacatat tcccaaacag
    34021 ctttgggaga tcgatcctaa aaaaatcgtg ggactgacga ataacccaga tattttaaac
    34081 aatatccgta aagaacggat gcgctcttac ggattaaatc ctgatactgc ttattccgat
    34141 atcgaaaaaa tacgagctga actcgatttt gcgaatgatc tttatgaaaa attgggctgc
    34201 gtagtaatca atgtcgcttc tttatctatc gaagaaacag cttcacttat tttgaatgct
    34261 ttagacctag aagatcatag ttattatgga actgaaacca ccgaagaaac agactaacag
    34321 tttttcttgt ctttttctta aaaaaactgg actgtgtcag cgaagaagat tcgttgatac
    34381 agtccagttt gtctctattt gcacctatcg ttattgatgt tccacatgtt tgagcgtctg
    34441 gttcaaaata tccagtacgt gagaatcatc aagactatac aaaatcgctt ttccctcacg
    34501 atgggacttg acgacatggt tttctcttaa taaacgcagt tgatgcgata cagcagattg
    34561 ttccatttct actgcttggg tgattgctgt cacattttgt tccccgtctt tcagatacag
    34621 cagaattttg agacgagtgg ggtcactcaa cattttgaat agttggctga ctttctctac
    34681 ttttgttttt tgcgtgtctg gcaatccatt cacctccaac ttgaaaaaag actgacttct
    34741 aaagtttacc actttttcca tcagtctcaa gtttttttat tcttctgtca tttttttgat
    34801 aatcgcttca taagcggcta ctttttcagc tgcgtcttct gaagagtttc cttttacacc
    34861 gatataaaat ttgattttcg gctcagttcc tgaaggacgg atagcgatcc agccattttc
    34921 ttccagcgta tacttcaata cgtcagatgg cggtgtcgtt agtttttcta cgtttccttc
    34981 acggtctgtt ctcgtcaact ctttgaagtc ttctgtttgg atgacttttg ctccggcaaa
    35041 ttctgtcggt gcttcttcac ggaatttttc catcaaagca gagatttttg cagagccttc
    35101 ttgtccgctc attgtcacag aaatcgtttt ttctgcgtag tagccatatg tttcaaaaat
    35161 cgtttgcaag ccgtcataca atgttttgcc ttgtttttta tagtaagctg ctacttctgc
    35221 taataagagc aatgcttgaa tcgcgtcttt gtcgcgaacg aaaggtttaa ctaaataacc
    35281 gtaactttct tcgaatccga acataaaagt atgggaatga tcttcttcaa attgttgaat
    35341 tttttcagca atgaatttga atcctgtcaa tacattgaac atggtagccc catagtgttc
    35401 cgcaattgct gtaggcaatt cgctagaaac gattgatttc aataccgctg cattttcagg
    35461 taaagtgcct cgcgattggt gtgcttccaa aatatattga gcaaacaggg ctccgatttg
    35521 gtttcctgtc aatacttcat aggagccatt tggcaaacga acggctgcgc ctaaacggtc
    35581 tgcatcagga tccgttgcaa tcagtaagtc agcgccttct ttctcgccaa gtcgcatcgc
    35641 atactcgaaa gcagagtgtt cttctggatt cggtgatttg actgtagtga aatccgggtc
    35701 tgcgacagct tgttctggaa ctagtacgaa ttgttcgaat ccagcttgtt tcaacgcacg
    35761 ttcgcccaac atttttcctg ttccgtgaag tggtgtgtac acaagcttca aatctttacc
    35821 cattgtttcc accaattcat gatcaatcgt tactgctttg atttcttcta gataagcggc
    35881 atccacttct tctccgatga tcgtgatcaa tccgctatgt tcagcttcgt cgtcagataa
    35941 tacttcaact tttaacggat tgctgacttc acggacatat ttcgtcaatg catctgcgtc
    36001 tgcaggaggc atttgtcccc catcttctcc gtagacttta tatccgttgt aagctgctgg
    36061 attgtgggat gcagttacca tgattcccgc aaacgtcttc aaatgacgga ctgcaaaaga
    36121 aagctctggt gttggacgta aactttcgaa tacataagaa gggatattgt gatgtgctaa
    36181 tgttttggct gcttccatgg caaattctgg tgattgatgg cgtgagtcat aagcgatagc
    36241 gacacctcgg cgttttgttt cttcaccttg tgtatccatg aaacgtgcaa gtccttctgt
    36301 tgcttgtctt accgtataga tgttcattcg attgatccca ggtcctaaga ttccccgcat
    36361 gcctgcagta ccgaattcca acggtgcata aaaagcatct tcaagttttt caggatcttc
    36421 acccagatca tttaattgtt tttttaagtt ttcttctaaa ttttcttcat gtacccattg
    36481 ttcatacact tgttcccaag acatgaaaat aacacctctt tctgaaatat ggttcttaat
    36541 aagtatagca ttcacttatt agatatgaaa gtatgaggac caaaaaacgc ttaaatcaag
    36601 aaaagattct tttatcaagc acggttacaa gtattcgcat aaatcggatt cagtagattt
    36661 cacgcaaaaa aaagagtaaa agaacaattg aaaccgttct ttcactcttt ttaaacttat
    36721 gcagttgttt cttctaaaga ttccaagtat ttatacactt gttgtccagc aatcccacca
    36781 tcaccaacag cagtagtgat ttgtcgcaaa tctttttcac gaacatctcc gatggcaaaa
    36841 acgcctggta tattcgtctt catttcgttg tctgttggaa tccagccggc ttcgttcgtc
    36901 aacccagctt ctctaaatgg tgcagttaat ggatccaatc ctacatagat gaatactccg
    36961 tctgctgcca aatcaaactc attgccagtt ttgacattac gtgctttcac acctgtcact
    37021 accatttcat ttccaacgat ttcgtcaacg actgtatccc acataaagga aattttttca
    37081 ttcgcaaatg cacggtcttg gatgatcttt tgtgcacgta attcatctct acggtggacg
    37141 atgactactt cagaagcaaa ttgtgtcaaa tagatggctt cttctactgc tgagtctcct
    37201 cctccgatca ctactagacg tttgttacgg aaaaatgcac catcacaaac tgcacagtaa
    37261 gaaacgccac gtccagcaaa ttcttcctcg ccaggtacgc ctaatttacg gtggatacag
    37321 cctgttgcga taatgactgt ttttccttcg taagttttat cttcacaaat aacttctttg
    37381 tggctgccgt gatccttgat atcttgcacg attccataag cattttctgt cccaaatctt
    37441 gaaacacctt catacatctt ataagctaga tcaggaccca tgattgaatc gaaaccagga
    37501 tagttttcga tttctgccgt attgttcatt tggccgccag gagcgccttg ttcgatcatc
    37561 aatacggata agtttgaacg tgaagcatat aaagcagcag tcatcccagc aggccctgcg
    37621 ccaataacga ttacatcata catatgtaga ttctccttta cttaatcaag taagcatact
    37681 ttacagccaa tgcgaaaaaa agtctattgt tctgcttgcg tttctcgaat agctttatta
    37741 tactcgaaaa atccgctgaa aaacaataga cttttataaa tcattgatca atcgttcgaa
    37801 agattttctc catttgaatc aattactttt ttataccagt tgaatgattt cttcttcgaa
    37861 cgggctaatg tgccatttcc ttcgttgtca cgatcgacat aaatgaatcc gtaccttttc
    37921 ttcatctcac ctgtaccagc tgatactaaa tcaatacatc cccaagtcgt atagcctaat
    37981 agatcgactc catctaattc tactgcatct ttcattgcct ggatatgtgc tgccagatag
    38041 tcgattcgat aatcatcttc cacataacca ttctcatcgg gcgtatcgac tgcacctaag
    38101 ccgttttcta caataaatag tggtttttga taacgatcat aaatatcatt catcgttatt
    38161 ctcaagccta atggatcaat ttgccaaccc cattcacttg cttccagata tggatttttg
    38221 acagaagcaa agatatttcc tgcagtctgt tccaagagtt cgttgtcagt agtcgaaact
    38281 cgagaagaat aataagaaaa ggagataaaa tcaacagtat gttctttcag caatgcggca
    38341 tccccaggtt ccattttgat ctgaatgcca tttcgttcca tttctttcaa tgcataagcg
    38401 ggatattctc ctcgtgactg gacatcaatg aagaaataat tttctcgatc tgactttcta
    38461 gaagcccaaa catcttcagg attgcaagtg tatggataat atgctcctgc tgccagcata
    38521 cagcctactt tgttctccgg atctacttca tgagcgatct tcgttgcgat ggcacttgca
    38581 accaactcat gatgtgccgc ttgatatttg atttgttctt cattttctcc ttcttcaaaa
    38641 tacagccctg cgcccatgaa tggtgcatga aggatcatat tgatctcatt gaatgtcaac
    38701 caatatttga caagtccttt atagcgattg aagatgactc ggcacagatt ttcataaaaa
    38761 ccaacgagtt ctctggaacg ccacgcacca tattctttga tcaaatgcat cggacaatca
    38821 aaatgtgtaa tcgtcacaag cggctcgatc ccgtactttt gacattcttt aaagacatcc
    38881 tcataaaatt tcaacccaga ttcatttggc tctttttcat cgcccattgg aaaaatacga
    38941 ctccaagcaa tggacatccg ataagtcttg aaccccattt ctgcaaataa agcaatatct
    39001 tccttataat gatgatacat atcgatcgca atttttgctg gataaaaatg attttcatca
    39061 aattcaaaca ttttcttttt tccagtaatg acaggaaaac ggtcttctcc gattggcaca
    39121 acatctacgt tcgctaaccc acgtccgcct tcatcataac cgccctcgca ttgattggct
    39181 gctgtagctc cgccccataa aaaatctttt ctgaatccca tcatacttcc tccattacat
    39241 gtgtattgct tgataattct cttgccagtt catcttggac ttcgattcct tctgctttta
    39301 accggctgat tgtttccttg aattgcggta aatactgctg atgtgcaata aacaactcat
    39361 ccatgatccg ttttgctgtc tttcctgatc gtataagcgg attgatcgta aacgcttgca
    39421 aagctgttcc ataatcacca gtcacggctg cttcgatcgt cagcaattcc atattcttca
    39481 ttacttgcaa ccagcctctt tcagcagcag gaagggaacc aaacgctaca tttcgtgcgc
    39541 cttgtgcgcc aacataggca gtgacttcta ctacacaatc tgccggcaga tcaggaacag
    39601 ctccatcatt ctttgtagat accacgatct gtgtttcttt atttccatag atcgaagcaa
    39661 tcgtttcaca ggcagcatct gaataataag caccacctcg tttttgcaat tgttcaggtt
    39721 tatgatccaa ttctggatct ttgtataatt caaacagctc tgcttctgtt tctttcactt
    39781 gctgcgctct tgtaccaatc gtttgatatt cttctaaagc atgttccagc atttcttctt
    39841 cacgatagta atagcggtgg tagccacaag ggatcatgtt catttgtttt aattgttctt
    39901 tgaaaaacgg gatgtcaaag atatttttcg gcaatccatt gtcttcatcg tataaacgat
    39961 caatcaattc tgccgtgcgg tcatttcctt tattatctgc tactttgtgc caatggaagt
    40021 gatttagacc ggcaaacttg tagatcagct cttctttttt cttgccaagc attgttggtt
    40081 ctgtcatcat cgccattact ggcacattgc ataatccgat cactttatcc catttgccat
    40141 atctgataac tgcttctgtc accatcccgc ttgggttcgc gaaattaatc agccaagcat
    40201 ttggacataa acgcttcatg tcttcaacga ttgccaaaac cactggaacg gtacgaaaag
    40261 ctttgaatat cccgccagca ccatttgttt cttgcccaat catcccataa taactaggga
    40321 tccgctcgtc tttgattcgt gcatctaatt gaccgacacg aaactgagtc gtaacaaaat
    40381 ccgcatcttt caatgcttct tcccgatcca gagttgcata gattttgact tcatacggag
    40441 aagcatccca catacgctga gacatctgac tgacgatctc aagcttttct tttccttctt
    40501 ctacatctac gagccagatt tctcgtatcg gtaattcctc atatcttttg ataaatcctt
    40561 ccatcaactc gggggtgtaa ctgctgcctc caccaatcgt agcgattttg attccttttg
    40621 ccatgttctc actcctttac tttttacact tttattatct tttttgtaaa caaaacaaac
    40681 aatagaaatt cgtttctttc cagtaacatt tacaaaagtt agtgttttct tctggatttt
    40741 tgtaaatatc ttgtcaaaaa atgtctttat taagctatat aacataaatc cgtttacaaa
    40801 tcattttcaa aaaagttata atttacgtaa aaaaacaaga agaaggtatc tacatgttat
    40861 tacgtgaaaa aatcaaagaa atctcctttt ctccttcaga aaatgaagtg attcagtttc
    40921 tcttaagcga ttctccagca cttggcgaaa tgaccatcca agagattgct gagcgatgtt
    40981 atgtccaccc gtccacactc atccgtgtag caaaaaaaat gggttttgat ggctgggtca
    41041 gttttcgtaa tgctttttta gctgaaacag cctatcttga agggaatttt caagacgtag
    41101 atgcgaatct tcctttttcc accacagacg gtattatgac gatcgcaaat aaaatggctt
    41161 ctttagaaca gatgacgatt caagatacac tttctctcat tcatcatgac caactgcaaa
    41221 aagccaaaca actaatgctt caagcaaaaa aaatcgtgat tttcgccagt aactcgaata
    41281 ctttgatttc tcaagatttc atgctgaaaa tgaagcgcat caaaatggat gtcacgattg
    41341 tcaccacttt tggtgaatcg ttctatgaag cgtacaattg cacaagtgat atgtgtggga
    41401 ttctgatttc ttatacgggt gaaaacaatg tgatccttcg taccgcagaa atattgaaac
    41461 aaaatcatgt gccaatttta gctttgacca gtatcggtga ttcaacgcta tcttcaatga
    41521 gtacagccgc tttgcgactt acgacacgcg aacgactgta ttcgaaaatt ggtaatttta
    41581 cgatcaatac atcgatttgt tatcttctag acgtgttata tagttgtgtt tttgcagaaa
    41641 attatcaaca gaatttagtc catctaattt ctgtaggaca aaaatttgat aaacgcccta
    41701 tcagctcagc catcatgaaa gagcctttca attttgaaaa taaagaagtg gactaaaaag
    41761 aatagttaag cctagtccat tctttcacct aaccgttcag gtcagtgcgg tgataagtgc
    41821 atcgtctggc ccgaccgttt ccccttgatt ttccaaaata tccaaataat ccatgtaatt
    41881 gatgacaatc acaggtgttt ctaaactgta tccttcctct tcgattttct ttttgtcgaa
    41941 gcgaagcaac agatcgcctt gtttcactct ttctccttgc tgcaccaagc tttcaaaata
    42001 tttcccttcc aactgaacag tatccaatcc gacatgaatc agcaattcca gacctgcttc
    42061 agaaaccatc ccgattgcat gtttcgtcgg aaacagggac atgactgttc cgtcaaaagg
    42121 ggcacgtact tctccttttt cagggtagat caagattcct cgacctagtg ttccttgtgc
    42181 aaaagctgca tcctttgctg cattcagtgg agcgatttgt ccttgtatcg gtgtttttac
    42241 aatttcttta cctgatcttt tctgtctatc atctgtttca tctgcttcct ccttccaaaa
    42301 gaaaaaagtc agcgcaaagg ataccaccat cgcaatggcg atcccaatca atacattaat
    42361 cacatctgtt aaatcaccat ctggtctaat atagttggga attgtaaaga tgcctagtcc
    42421 accttgattc caagaagtta aattcattaa cccactatac gcgcccccta acgcaccacc
    42481 gacacaggta aaaataaata tttttttacg tggcaatgta aacccataaa tagctggctc
    42541 tgtaatcccc acaataccag aaacaatggc tggtattgca attgctttgt cttttggatt
    42601 tctaagctta aagtagagtg cggtaagtgc tgcagtttgt ccaaaagaca ctactgcaac
    42661 aggtgtcata atattttgcc aaccattcac agaaaattgc atcaatccca ttggtacgat
    42721 tgcccaatgg agaccaaaca tcaccagaat ttgccagaag aagcctacga ttgctccata
    42781 aataactggc gaaagtgcta aaagtgtttc aaatccagcc attaaaatat cagttgcgaa
    42841 tgtgaatact ggtccaacga gtaaaaaacc taaaggcatt gtaataagaa cggtgaagaa
    42901 tggaacgaag aaattcgcga tcatctcagg tactaacttt ttaattggtt tctgaatttg
    42961 gctagctaac aacacaataa agataatggg aatgacagaa gaagcgtagt tacgcgcaat
    43021 ccagggaatg ccgaatactg tttgataaat aggtgcttca aaaatagtgc cagaaaatat
    43081 ggtcgttagt ggtgcttctg ctgcaccact caaagcttcc agcgacaagc taggattcat
    43141 taatgctgcg ccaagcaaca tccctacgaa ttcatttact ttaaatttac gggcagctgt
    43201 taaaccgata ataacaggca taaattggaa tacagaatca ccgatattat caaacataac
    43261 aaatgtgcca gaaccgcggt caaacgcgcc taagaagaca aggaatgctg tcagtccacg
    43321 aatcatcccg tcagcagcta ggatagcaag gaatggttgg aaacagcccg atattccatc
    43381 aataagcata tcaaacggtc tcattttttc tgttgaaaca gcctcatcaa aagtaaggtt
    43441 tcctgctttt ataacctctt caaacacgac tggcacatga ttcccgatga caacttgata
    43501 ctgccctccc gctcgcatta ccgttacaat accgtccata tttttcaaga tctcatcatt
    43561 tgctttttct tcgtttttta atttgaaacg aagccttgtg atacaatgtg tcaaaccatt
    43621 gatattttcc ttcccgccga cattttctac gatttttctc gctaattctt ggtattttcc
    43681 catttctatt ccctccaatt tattagtgga aggtttagcc aactgaatgt cactaccctt
    43741 atttcatacg ttcttgttaa tttatcctcc tttttttatt tatttacaac gattctcatg
    43801 cactaaacgc gcagtatgga tcgttaaata cattttttcg tccgtggaca tctggtagtt
    43861 gaacgtctcg gctaaaaagt ctgctatttt ctcaacgcaa ccaaacgtat ccttatattt
    43921 tttttgaata acctgaaaca attcctcaga aacttctccc acttctgatt tttctccatc
    43981 taggacgcgt gtcagaaaaa aacgtaagtg tgtgacgaat cgaaaaaaat ggactgaatc
    44041 ttcatcaaat gtaatcttat agtaatagcg gacgatattt agaatatcct gtattgttat
    44101 agtgaacagg taggtattgt cttgttggct ttgaatgcct tgtgcattga ctaaatgcaa
    44161 tgcgataaat ccggcttcat cttctgataa cttgatgtgg tatttatccg agattttctt
    44221 cactgttttt tttcccgatg gcatactctt taggaaatag ttgtttgata tcatacagca
    44281 atacatttgg tacaaatatt cccattttgt gacgttcgat agccgtatac aaatgatccg
    44341 tcaatgcaat atacacagaa tcattcaact ggacttgtag agcctctttt gtatattcaa
    44401 tgatttcaca agaaatttct aagtactcaa gaggaatcgc ttgtgccaat tcttggaact
    44461 gttgtgaaag cccgtcattt gtcaactgaa attttttgtc gatgcatgag tcaaaaatcg
    44521 ggtcacccac tttctttttg aatgccaaac cttttcccat cacgatcatt tcctgatttc
    44581 tttcatccct ggttattacg acgttgttat tcagtacttt ctcaatcagc atgttttgct
    44641 cctttccatg atatataggg ctgtatccaa aacaaaaaga aaaacccaaa aagccgtcca
    44701 tggaaccatg ggagactcat caggtttagc ttgcatcagg caatcactat ccaagttgta
    44761 tcgttttctt tatattatcg aaagcaaacg cttttgtcaa cgctttctta gtggttatta
    44821 gccgcttttg actagctgtc gtcgtctttt ttaaatcggg tgactacgcc actaacgctc
    44881 acagatgaag aatctgcgaa gctctgtttt attttcactc tagcgcttag ggcaaaatgc
    44941 tactatgcta ctgtcacaac ctctttttac acaccactgc tttgcagttt gtacatatct
    45001 gcatacaaac cattttgcgc tagaagtgtt tcatgattcc cacgctctac tatatgacct
    45061 ttgtctaaaa ctaaaatcaa ttctgcatcc cgaatcgtgg acagccgatg ggcaatcgct
    45121 atcgttgtcc gtccttgtcg catttttgcc aatccttctt ggatcaatcc ttcggtttca
    45181 gtatcgatat ttgctgttgc ttcatccaat actagtattt taggatctgt cacgattgtt
    45241 cgcgcaaaag tgatcagctg tcgttgtcca ctagaatagc tggcaccgtg ttcgatcact
    45301 tttgagtgat atccttttgg taattcatcg atgaacttgt ttgcttgaac aaactcagct
    45361 gcatggcgaa tctgttcgtc tgtgatagct ggattcatca tccggatatt tcctgcaata
    45421 tctccataaa acaagaaggc atcttgcaag accaatccca ttttcttacg taactcttcc
    45481 attggatatt ctcgaatgtc atgatcatca atcaagattt ggccttcata aaattcgtaa
    45541 aaccgcatca atacgttgat gatcgagctt tttccgcttc cggtgtgccc cactaatgca
    45601 acggtctcac ccggattagc gacaaaagag atattgttca atacattgtg ctctccatca
    45661 taagaaaagc ttacattgcg aaactcgatc ttacctgaag taatcgcttg atctgctcca
    45721 ggattttgtt gcggtgcata ttcttctgta tccatgattt tcaaaatacg actaccggca
    45781 accatcccat ctgtaaaggt gctcaaaaag tccatcattt gagacattgg attaaaaaat
    45841 tcctggacat aggtcgtaaa tgcatagatc agtccaactt ctacgggaga atgcaacgca
    45901 tcgatcccaa acaaagtcaa cgccaacgca atcgccaatg catagagaaa attgatgatt
    45961 ggacttaaca gaatcgaatt cgttttgatc atcgcatagc gcgtgtctaa atactcgttg
    46021 ttcacttgtt caaattcttt agctaaacga gcttcttggc gaaactgctg gataatacgc
    46081 atgccggaaa tcgattcatt caatttcgtg ttcagctgac ttaatttttc ccgcatattt
    46141 cggtaaatac gagaactgaa tttctggtaa taccagatga cgattcctaa aatcggcaag
    46201 aacaccaaag tccacaaggc aatttctcca ttgatttgaa acatggcaac gaaagaagaa
    46261 acgactgcaa agatcccagt caataccatc aaaaagacat accaaaattc aaatagcgtt
    46321 tctgtgtcat tcgtcactcg agaaacggtc gatcctgccg gtgtctggtc aaaataacgc
    46381 atacctagtg tatgcagctt ttcaaataat cttacccgaa catactgata ggtcttcaat
    46441 gaagccatgg aatacaaata ccattggaaa aaccaaatga tacttttgac tatgactcca
    46501 aacaagtaca caccagcaaa aaacaaaata acttgtgtcg tagctgactg tttagccaga
    46561 tgatcatcca taaaagtttg gatgatcctt ggcaatagga cattgatcac agacagggca
    46621 aacgcaaata agatagcaac gatgaacgtt cttctaaaag gtttggcgaa cttcatcagt
    46681 cgtttgatga tcttcttctg ttctttaagt ggaatcgatt ttgtccattc cgattgataa
    46741 ttttcatcca tcaggcctcg cctccttcta tcttcgcttc taattgctgt ttttcccaca
    46801 ttcgttcata ccagccacct aatgcaagca gctcgtggtg ggttcctcgt tcaatgattt
    46861 tcccttgatc gacaacaatg atttcttttg catgcatcac gctgcttaaa cggtgagctg
    46921 caatgatggt tgttttctct tttcttattt cttttaaatt atgcaagata gcttcttctg
    46981 ttttggcatc tactgcagaa agtgcatcat ctaagatcag caattcagga tttttgatca
    47041 atgctcgagc aatcgaaatc ctctgtttct gtccgccaga taaagagact ccacgttctc
    47101 caactaaggt atcataacct tttggcaatt ccttgatttc attgttgata aatgctaaag
    47161 aagccgcatg ctctacttct tcttctgaaa gttttggatt agaaaaacgg atattatctc
    47221 gaatggtcat cgaaaacagg aagtgatcct gaggcacata accgattgat cctaataaag
    47281 cattcaatga atattctttg atcgaacgtc cgccaaattg gattttccct tgataatcat
    47341 cgtattcacg catcagtaat ttgatgattg tcgtttttcc cgcaccagtt ttcccaacaa
    47401 tacctaatgt ttctccttct tggatcgcaa atttgatttg ttctaatgct ggtgattctt
    47461 ctttcggata gttaaaagag gaaatagcta cattcagctc gccttttgcc ggggtctgca
    47521 ctgcacccag ttgttccacg atatgcgtct tttcatgcaa aagttcattg acgcgatcat
    47581 aagaagcatt tcctctttcc aatacgttga acaatcgacc aatcgcaaac atcggccaaa
    47641 caagcatacc gatatagcta ataaatgaga ccatctgccc gattgagatc gtgccttcca
    47701 agacatactt tccacctaaa ataattgttg caacataaga cagaccgata atcaaggtaa
    47761 tgaatggatc aaataaggag tctaaaaaat tgactcgttt gtttttaata attgcatctt
    47821 caatcttttc ttcaaaatcc gcgagatctt ctttttcttg tccaaatgtt ttaatgactt
    47881 tgatcccagt gatactttct tgtgtcttat cattgatact agaaaaagct tcttgcgaat
    47941 cacgaaaagc atcgtggagt tttgacccca gcactcgtga agtaacggct agcaaaggca
    48001 gaggaatcag cgcaatcagt gttaagcgcc aatcaataaa caaaatcatc gcaatgatcg
    48061 ttgttccgcc cgtaatcact gaatctgcaa aggtcaagat tccagctcct gctacattct
    48121 ggattgcatt caaatcattc gttgcatgag ccatcaaatc tccagtccga tatttttggt
    48181 aaaagagatt gtccatttct gtaaaatgtt tgaatagctg ctgccgaagt tctctctcca
    48241 accgagctgc acttccccaa atattcgtcc gccagatata acgaaaaaga tattgtaaga
    48301 aagctgcaag gatcaataat aagatccacc aggaaatgat ctttattgat aaattcttat
    48361 cggcgatctc atcaatgatg atcccaatca cttttggagg aactaactgt accaaggcca
    48421 ctgcgaatag ggagaaaatc ccaattaaat aatgtttctt ttcctgacga aaaaaccaac
    48481 ctaattttct aaaaatcgac attttactcc tcctttgtct ttatcaagag cataggattg
    48541 tctgtgcttg tcttttttgc tgaatagtct gaatagtcta acaaattacg aaataaaaaa
    48601 cggactgaaa aaatcagccc gcaaaaagtc tttgggtcag aacctatttt ttcccttggt
    48661 tcttcatttg ctgcatcatc tggcgaattt tcttctcaga tggtttttgc cccattgaca
    48721 tcatcattga tcgcaacatg tcctcattaa cgggaggatt tttttctaaa tagtctttca
    48781 tatatttacg cgctaggaaa aagccaccta ctgcgccgat tagcaaagca ataatagcaa
    48841 taagtacgac aatacctgtt gataccatat aaatctctcc tttctatttc cgaattgctc
    48901 tcaatgattt attttactaa agtttattga aaaaagaaag gcgtattctt tagtttcatg
    48961 caaaaaatag tggttttttt agagaagaac aaaatttctt tcattaacca gcaagacaca
    49021 ccacgaaaaa aaaattaggc ataccgaatc tttttcttta attttttctt tctgaggtgt
    49081 agaatgtaat cgtagataaa taggaaaggt ggttttttct tgaataatca atccaacaaa
    49141 caatttcata agcatcgact tattgaacat acaaatggtt tatctttagc tgaagtaaat
    49201 ggaacagtgg atgtaccaaa gggaaaaagt ttttttaaaa cacttcttgc ttactctgga
    49261 ccaggtgcat tagtagcagt tggttatatg gatccaggta actggtccac ttcgatcact
    49321 ggtggacaaa atttccaata tttattgatg tcagttattt tgatgtctag tctaattgct
    49381 atgcttttac agtatatggc agcaaaatta ggaatcgtga cccaaatgga tttggcccaa
    49441 gcaatccgag cacggacaag taagacattg ggtgtcattt tatggatctt gactgaatta
    49501 gccattatgg caacagacat cgcagaagtc attggtgcag caatcgccct ctacttactt
    49561 tttgatattc cattggtgat tgccgtcttt attactgtat tagatgtttt cgttctctta
    49621 ctactgacaa aagtcgggtt tcgtaagatc gaagcactgg ttgtctgctt aattttcgtc
    49681 attttattcg tttttgtcta tcaagttggc ttgtctaacc cagattggca cagtttattt
    49741 gctggcttta tccctaacag tcatacattc tcagactcac cggtcatcgg cggcgaaact
    49801 ccgctgactg gagctttagg gattattggt gcaacagtca tgccgcataa cttatatctt
    49861 cattcagcag tttcacaaac tcggaagatc gatcaccaaa acgaagaaga tgtagcacaa
    49921 gctgtacgtt tttctacttg ggattctaat atccagttgt caatggcttt tctagtcaat
    49981 gcactgctat tgatcatggg tgtcgctgtc ttcaaaaccg gttctgtcca agatccttcc
    50041 ttttttggtc tgtatgaagc tttatctgat ccatcagcta tgagcaatgg tattttgatt
    50101 gctgtagcaa aatctggtat cttgtccact ttatttgctg tagcacttct tgcttctggc
    50161 cagaactcta ctattactgg tacgttgacc ggtcaagtca tcatggaagg attcatccat
    50221 atgcgtatcc cgatttggct aagaagactg gtcacacgat tgctttccgt gattcctgta
    50281 ttgatttgtg ttttgtttac aagtacaaaa ggaacgatcg aagaacatgc cgctttgaat
    50341 aacttaatga atgaatccca ggtgttcttg gcttttgcgt tgccattttc gatgattcct
    50401 ttactgatga tgaccaacag ccaagcggag atgggtagcc gatttaaaaa ttcattcatc
    50461 gtaaaacttc ttggctggtt ctctgtgatt agtctaactt acttgaactt acgaggatta
    50521 ccaggacaga tcgaaagttt cttcggcgag caagccactt ccgctcaact agcattggct
    50581 gatcacatcg cttatgtaat cattgttctt gtccttctcc tgttggcatg gacgattggt
    50641 gatttatata aaggaaacaa aaaatatgaa cagcttttgc aggaaacggt agaagaaatc
    50701 gaataaaaac tgatttttcc acacaaagac ccttgatagt taggttaaaa atctagctac
    50761 caagggtctt tttatttaga agataaagct tttttcagat ttaatttact gaaaactagc
    50821 atgcttgtta ctacgatgaa ttgcgttaat ggcacgcctg caccagtgta gacacttaaa
    50881 aaatagtcct ttttttctgg cgcataagaa caaaaccatg agacaccgaa aagaaaaacc
    50941 aattgtgtca gtattaatcc ggtgaccaca atcaaagagg aactataata ggcacgatca
    51001 gcttttgcaa atacggttcc tagtatcata agtaatatcc ctgctattga agcaatcagc
    51061 acgggaatag ccagaacttg gtaaattttt atgatgacat tcgcgacttt tgctgatttt
    51121 gttaattgga aattaggtgt tctcggttca ttactatcga tccaattctc cattagcgga
    51181 aggtttaata attcttgagc ctgtttgact tgttcttgcg ttccgaaact ataatttcct
    51241 ccttgatgga aatctttata tcgccatgca taagcgtatc ctgattgaag gaaatcgaat
    51301 acgattggca gatcactcat cgtctttcca tctcctgatc ccatcagata gaactctttt
    51361 ttctttttga tggttccctt gtgataggct tcttctaatt cttggttgac ttttttccaa
    51421 aaatcattgg tttcttttgc attgttttgg taataaccag attcgcttac cacatctcgc
    51481 aatgcccaaa agatgatatc tccgggtaat tcttttactt ttccaccttg agtccacgcg
    51541 tgagtcgtat ataattcgtc aatacgggta gaaacagtat ggaatgtagg agatgcggct
    51601 aatgctttat ttagtgcagc atgtgagacc catatctcac tgttttcttt attcaagttc
    51661 gtttcatcat ctattcggat cagttgtttc atcaaacgtc caaattctcc actggaacgg
    51721 tcattgatgg ttgcaatacc gtatgttgtc tcatttttat attcgatcca ctgatagacg
    51781 atggaaaagc caactatagg aagtaaaaac aatgaaagtt tcagccattc ccgtttcgag
    51841 agaagaaaga gtcgtttttt taacttcttt acttctttga aagaaaagtc ttgccctagc
    51901 aagatctgga cgaaactgat acccaaagct actacagtaa aaggaagaag ccagatagaa
    51961 tcttcgcgaa tgaaccaaaa gaaaggaaaa gcgacagaaa gccctaaaaa ccatggcagc
    52021 aattttctgc tagaaccgta tttgcggtaa taaatagcta ataaacaagc gataatgatc
    52081 tcaacagccg gaatcacgag ggcattacga tatgttcgag tggaatattc atgtgtaaaa
    52141 ctaatcggag aaaacaaaaa ataaaaatag atacttaaaa gaagatactt gttcttcaca
    52201 atcggtttaa acgcgagtgc aaccaatata ctggcaaaaa tactgaacat gccgaacaaa
    52261 actgcataag aaagatgcag tttatgtgca agtactaaaa ataagctgta ggagattcct
    52321 ttggaaagtg ttgtagtcgt atactcccct agccatttac catccaaaat attttgagca
    52381 tagtgaatca gcagctgatc atcataggtc gccgacatat ctgttccata gattgcttta
    52441 ctatataaat acaaccgaat aattgtaaat aatacggcta tgccaagaat aaagtatgta
    52501 tgtttctttt ttagttggtc gatcaagggg tttaaaatgt tcagcatctt ttcgtccttt
    52561 caatcacgtt ttgctacttg tttgtgaaac ttttcgtttt ttacttttct atcagtatac
    52621 cctgtttgtc tgaatttaaa aagagggggc aaaaggagca tggcgaaaac gaatgcaaaa
    52681 agcactcctt tgtttcttaa acaaaaaagg acaaggcaga ctgcccaatc cttttttgtt
    52741 gctgtcaggt agaaaactta aagtgtgact tcttctgcta ataactcagg gaacacttcg
    52801 ggatcgaatg cttgcgcttt gaacatggaa atttcttttc catatggtgc gtaagctttc
    52861 tttttatctt taccgacata tggggtttct aatattttcg aaatgttgtc aaacattgga
    52921 tcatggacga ttttgttcaa tgtgtcaaat ccaattgttc caaaaccgat attggcatgc
    52981 cgatctttat gagaaccttg tggattttta gaatcattga tatgcagtac tttaagccga
    53041 tctaatccga tgaccttatc aaactcttcc attacacctg aaaaatcttc ttttatatta
    53101 tatccggcat cattcgtatg acatgtatca aaagtaacgg ataatttttc attcaatttt
    53161 actccatcga tgatttgcgc taattcctca aatgttcgac cgatttccgt acctttccct
    53221 gccatcgtct ccaaagcgat ctgtgccgtc tgttcttttg tcaaaacttc attcaacccc
    53281 tcaataattc tagcaatccc agcttctgcc cctgctccta catgagcgcc tgggtgaagg
    53341 gtgatttgag tagcacctaa agcttccgca cggacaatct cttctctcag aaattgtaca
    53401 gcaaatggaa acatttctgg tttgatcgta tttcccaaat taatgatata aggcgcatga
    53461 acgacgatat ttgttagtcc gttttctgcc ataaatgctt ttccggcatc aatattcatc
    53521 tcttcgatag cttttcttct agtattttga ggagcgcctg tatagatcat aaaggtcgaa
    53581 gatccgtaac tggctgcttc ttctgccgcg cctaacagca ttttctttcc gctcatgctg
    53641 acatgtgagc ctaataacat ggatggattc ctccttgaaa ggcaattgtt tcgaacaatt
    53701 cctgtatatt gataagatga tgtacaaaga aaatggtttg tttttctttg ccctgttctc
    53761 catagtaact gaaactttcc ctaaagaaaa gcttaagaac tctttcataa aaaagatcat
    53821 ttcctcacgt tttatctcat tcgaaaaaga aattcctgtc aaaaacagcc ttgtctgttt
    53881 ttttgtccta ttatttgcta taattagcga aataaaacca ttagttgagg tgaccctttt
    53941 gccacgcaaa aatactcgaa aaaaacagaa tagaagaaaa aaagaaaaat ggtttgttcc
    54001 taagattatt tttagagtgt ttcaatcatt gactgttttt attactgttc ttcttttgtt
    54061 gttcgcagct ctaggtatcg gaataggtgc tggctacttt gcctatcttg tcgaagacac
    54121 acaattgccg actaaaaaag aactgcagac agaactagga aacattacgg aaacgtcaaa
    54181 gattgtttat gcagataata cagagatatc aaaaatccag acagatctga tgcggacgac
    54241 tatttcatct gataagattt cgcctttatt gaaaaccgcg attatcagta cagaagatga
    54301 atacttcgat aaacatcaag gttatgtccc taaagctgtt ttacgagcac tagtttcaga
    54361 agcgactggc atcggctcgt ctggaggatc cactttgaca cagcaattag tcaaacaaca
    54421 gatcctaacc gatgaaacaa cattcaaacg taaagcaaac gagatcgttc tttctgcaca
    54481 agtagaaaaa cacttttcaa aaaatgagat cattactacg tatttgaatg tctcaccatt
    54541 tggtcggaat aataaggggc aaaatattgc tggagtccag gaagctgcta gaggaatctt
    54601 tggtgtagat gcaaaggatg tgactctgcc acaagctgct tatatcgctg gtttgcctca
    54661 aagccctatc acgtatagtc catacacgaa tacaggcgcg ctaaaagaag atctttctgc
    54721 cggtcttgcc agaaaagatt ttgttttatt cagtatgtac cgtgaaggac aaattacgaa
    54781 agaacaatac gaagaagcga aagcctatga tcttacaaaa gactttctcc cacaacaaat
    54841 cgcggaacag actgacagag aattcttgta ttataccgtg atgaacgaag caacaaggat
    54901 tattgcacaa caattggcag aaaaagataa tgctgatatg tcagattcat cggtcagtga
    54961 agcttattat caaaaagcac agcaaacgat ccaaaacaaa ggatatacga tccattcgac
    55021 gatcgataaa gatatctatg ctgcattaca aaccggcgta gaaaattatg gctacatgtt
    55081 agatgatggt gctggtagcc aagtggagac tggaaatgta ttgatggata acagaaccgg
    55141 acgtatctat ggcttcgtgg gtggtcggaa ttacagccag aatcaaaata accacgcctt
    55201 tgatacagaa cgtcaagctg gttcatccat caaaccggtt cttgtttacg gtcctgcaat
    55261 cgatatggga cttgtcggat cagaatcccg tgtatcagat tatgcaacga cttggcaaga
    55321 aggaaaaaat gctggtgaga aaatcgtcaa tgcgaccaat gaagggtcga acaccttcca
    55381 aaccgtccgt gagtcactgg aatggtccaa caatatccca gcttatcact tatatcaaga
    55441 tgtgttgaat tccggtggat cgaaacaata cgcttacgag cactacttgg cgaagatgaa
    55501 ctacccagca aatgataatt ggggcgttga atcggctcct ttagggacag tagatgtaac
    55561 gacgcttcaa cagacaaatg gattccaggc cttagcaaat ggtggagtct acgaagaagg
    55621 ctatatcatt gattccatca cagataatgc aggtaatgtg atttataaac atgaaagtaa
    55681 ttctgtccgt atttattccg aagcaacggc atcgatcatg aatgacatga tgcgtagtgt
    55741 gatcaatgaa aaaatcacta caccattcaa agatgtcatc tcaagcttaa acggaaatct
    55801 aggaaatgca gattgggtcg gaaaaactgg ttctaccaat gaataccgag attcatggct
    55861 gatcgtctca actccatcta tcactatcag tagttgggca ggacacgatg acaatactgg
    55921 aatggacagc caagcaagaa tacgttcggc taattatctt gccaatctaa tcaatcaagc
    55981 ttaccaagca aaccctgaga ttttcggcac tgatgagaaa tttgacttat catccgatgt
    56041 gatgaagaaa aaagtatctg ggttcacagg acaaacagct ggaaaagtta ctgtcaataa
    56101 aaaatccatc caaacgccag gaaaaacagt ggagtcactt tgggcaaaaa atggtccgaa
    56161 gaaaagcgcc tttaaattcg gcgtaggcgg tactgatgaa aactatacag attactggaa
    56221 caccgcttca gcttatgcta gagcgaatcc agagaccaaa gaatcagacg ataaagatga
    56281 ttgatctaat agattaatca gaattaaagg gagctgcgac aaaaatcttg tcacagctcc
    56341 ctttttccga ataaatggtg ttcaaaagct tacatctacg atattaagac aaatttatgt
    56401 aaaaatgtga aaaac
//
LOCUS       DAFEIE010000010        55524 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFEIE010000010
VERSION     DAFEIE010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.010"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(212..1354)
                     /locus_tag="LP345_000699"
     CDS             complement(212..1354)
                     /locus_tag="LP345_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1759505.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGICLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(1359..1544)
                     /locus_tag="LP345_000700"
     CDS             complement(1359..1544)
                     /locus_tag="LP345_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBL1759506.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(1898..2143)
                     /locus_tag="LP345_000701"
     CDS             complement(1898..2143)
                     /locus_tag="LP345_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759507.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(2137..2538)
                     /locus_tag="LP345_000702"
     CDS             complement(2137..2538)
                     /locus_tag="LP345_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1759508.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(2723..4531)
                     /gene="uidA"
                     /locus_tag="LP345_000703"
     CDS             complement(2723..4531)
                     /gene="uidA"
                     /locus_tag="LP345_000703"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBL1759509.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KLITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDICKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWKERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAHYLQKRWSSIPNFSYKK"
     gene            complement(4554..6320)
                     /locus_tag="LP345_000704"
     CDS             complement(4554..6320)
                     /locus_tag="LP345_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBL1759510.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IISDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIEPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(6333..7127)
                     /locus_tag="LP345_000705"
     CDS             complement(6333..7127)
                     /locus_tag="LP345_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1759511.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYYQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGEYVDIEQKFIDTFWKNLTNK"
     gene            complement(7137..8513)
                     /locus_tag="LP345_000706"
     CDS             complement(7137..8513)
                     /locus_tag="LP345_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1759512.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLIIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQFKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKTSNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANIQTGDVLEKLYNASTLIPSICFFIVGLILFFLYPLSKDKVLENC
                     ELLKQKYK"
     gene            complement(8633..9280)
                     /locus_tag="LP345_000707"
     CDS             complement(8633..9280)
                     /locus_tag="LP345_000707"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBL1759513.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSLENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(9373..10800)
                     /gene="uxaC"
                     /locus_tag="LP345_000708"
     CDS             complement(9373..10800)
                     /gene="uxaC"
                     /locus_tag="LP345_000708"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBL1759514.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLGYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQAAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(10874..11953)
                     /gene="uxuA"
                     /locus_tag="LP345_000709"
     CDS             complement(10874..11953)
                     /gene="uxuA"
                     /locus_tag="LP345_000709"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL1759515.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLQTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIRKVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(11956..13587)
                     /locus_tag="LP345_000710"
     CDS             complement(11956..13587)
                     /locus_tag="LP345_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL1759516.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSNIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            13893..14564
                     /locus_tag="LP345_000711"
     CDS             13893..14564
                     /locus_tag="LP345_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1759517.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQHGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKINNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKSI"
     gene            complement(15267..15622)
                     /locus_tag="LP345_000712"
                     /pseudo
     CDS             complement(15267..15622)
                     /locus_tag="LP345_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15639..15806)
                     /locus_tag="LP345_000713"
     CDS             complement(15639..15806)
                     /locus_tag="LP345_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002404637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759518.1"
                     /translation="MQTLINALQGKNYDYAVKILLDVAKRSLTPAQFAKFNAATIAAG
                     IAINAISCWGK"
     gene            complement(15806..16213)
                     /locus_tag="LP345_000714"
     CDS             complement(15806..16213)
                     /locus_tag="LP345_000714"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759519.1"
                     /translation="MSRFFKFFSLLGVMLIGLSTLVGAGTSVYAAEKVNEVPDIETQR
                     QQAVESLKFYLEEAGYVDTETHQYIVTDLEAIQKKAELDGSEGIAGKFILENFVQPTG
                     KRQKRDLQKYAACVVMNSLPFGVLFGIYLIVKI"
     gene            complement(16714..16908)
                     /locus_tag="LP345_000715"
     CDS             complement(16714..16908)
                     /locus_tag="LP345_000715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759520.1"
                     /translation="MKDQKTNNKTGERSACSWAFTGAGLLHSGIYTAAALGLSLTGVG
                     AAVIPFAVGTAYGIAGAAIC"
     gene            complement(16922..17260)
                     /locus_tag="LP345_000716"
     CDS             complement(16922..17260)
                     /locus_tag="LP345_000716"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759521.1"
                     /translation="MKRIVKIFGILGVFLIGLSTFVSAGISVDASETNNFLVKQQETE
                     INIIQNNLATHKDSKGNRLVYIIDESDLKSSLDRINSEITVSEIQQYLNEFNRSIQKK
                     WPWMANRSAS"
     gene            complement(17304..17636)
                     /locus_tag="LP345_000717"
     CDS             complement(17304..17636)
                     /locus_tag="LP345_000717"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759522.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRKEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLVWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(17650..17907)
                     /locus_tag="LP345_000718"
     CDS             complement(17650..17907)
                     /locus_tag="LP345_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759523.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KVYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18102..18638)
                     /locus_tag="LP345_000719"
     CDS             complement(18102..18638)
                     /locus_tag="LP345_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759524.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLTTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDYMT
                     DRCIKDNSIDVDPHVQMKTTGKLHQVTQDIENPDQYLLFGEETTNEVTQFVLLQLKVD
                     QEAQKIDAIKIYYVRSVY"
     gene            complement(18659..19750)
                     /locus_tag="LP345_000720"
     CDS             complement(18659..19750)
                     /locus_tag="LP345_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL1759525.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEDGGEATGLAVAFNWE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESTYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKDCYDYYGFLVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYQGAMSIIKSYNLTEYDTFAIKHWNSLPTKK
                     SSLVAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YDWTAYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSDGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(19758..21968)
                     /locus_tag="LP345_000721"
     CDS             complement(19758..21968)
                     /locus_tag="LP345_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759526.1"
                     /translation="MAYIKRKEKKWCVWLFLTVGFGLFFVGGLVYAVEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYLLLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPAFDYMIMNTLKSFLSLMFQKSFYSVIILVAFLIY
                     NIVDDLILMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGGQVINPFELGGRSNQDLPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQSSKQQGNNQRKPLLNKGIAFVGQSIPLPAGKVPVPQLTAAGSLS
                     QQIHQVKNQAKNGSYPAMQQLLNQYSVPKSSVATLSGNRSVQRQIQRSSESKPSISVP
                     KSLQPAFSSFNNPVEQSKKIEKKNETLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(21984..24512)
                     /locus_tag="LP345_000722"
     CDS             complement(21984..24512)
                     /locus_tag="LP345_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1759527.1"
                     /translation="MVLVKEPVKALKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFYDVLNLIWLDVAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRMPKEHKGLLQLEDELGTSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEYKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATIIQQLHTTIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAIGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVEYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILTHLRLEVNEANLSEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQIEEQDTLIMQ"
     gene            complement(24566..24976)
                     /locus_tag="LP345_000723"
     CDS             complement(24566..24976)
                     /locus_tag="LP345_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759528.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFFIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYVV
                     RMMNGDCVYYNWDKVSNNALEELLFANKYVYLED"
     gene            complement(24989..25207)
                     /locus_tag="LP345_000724"
     CDS             complement(24989..25207)
                     /locus_tag="LP345_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759529.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(25204..26196)
                     /locus_tag="LP345_000725"
     CDS             complement(25204..26196)
                     /locus_tag="LP345_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1759530.1"
                     /translation="MKKRQLRRKEKVYTEKVPNQRKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSQSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQEILKKEFYAQNFIQEPGSVSGIRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMDPENKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKTFIVKATVVFRDGDTSLLQKEQMTLVITKKTNQYYVEKLTHNWLDRKGDERK"
     gene            complement(26275..27186)
                     /locus_tag="LP345_000726"
     CDS             complement(26275..27186)
                     /locus_tag="LP345_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1759531.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLSDVETELNGGTTEKPAEPEHLQPEKPEKEPVAPEPEIPESTLPTDPIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSETNTDSSSTEQPTMSFTSEEPKEEPKQPAEKSEAIPK
                     ENKPIVPAKEVTVSVTPNGEITTNNSQGMSVPIVTSNVEELTHIPTPTTPLKAEGGQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEVKTADGKTKVLPKTGEEIHVVLS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(27205..27549)
                     /locus_tag="LP345_000727"
     CDS             complement(27205..27549)
                     /locus_tag="LP345_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759532.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLGPRTERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(27569..28126)
                     /locus_tag="LP345_000728"
     CDS             complement(27569..28126)
                     /locus_tag="LP345_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759533.1"
                     /translation="MSLEFLGEPIEKEEFVSHYMDLFIRVIKKLCTIDEFYPREQDYL
                     AAERIKISLLWEKFTDENNRPPDYRYLSDCLTNNVLSKEYLFHKREKNQMSAEHFCDC
                     YIALLRSQQLLTVERYGAEFGYVMQAERHRATRCYEKEDQVIDGYEELCIRNNRYLQQ
                     RLYEKLMMDFSDLYRGYECSVIQER"
     gene            complement(28206..28706)
                     /locus_tag="LP345_000729"
     CDS             complement(28206..28706)
                     /locus_tag="LP345_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759534.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPKEYPIEKRELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPINFLKKC
                     HLRILP"
     gene            complement(28707..29252)
                     /locus_tag="LP345_000730"
     CDS             complement(28707..29252)
                     /locus_tag="LP345_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759535.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGTLKFIRFYRFSLPVPAILAVK
                     KGCDKMKIYENCVAALSNEKPLVEEISLATVTWEMNRQPTEEQTYLSLEEIELELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(29249..30505)
                     /locus_tag="LP345_000731"
     CDS             complement(29249..30505)
                     /locus_tag="LP345_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1759536.1"
                     /translation="MTPIELRNYRKKLSAIHASGGGKKLLSQKRFAQLLGCSVDYIKK
                     MEQGKKKIPEDFEKRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKIVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKQTVTQNVLVQFSGQGCREYEEVMREQRTD
                     WRTWLYSIWKNQGKLEAGYKRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKKFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISEIEAL
                     TKYGIYNRYELRLANEKATQAVEAFILDHSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDERWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIENAELNDEQQSYLEWMGTSGGKIA"
     gene            complement(30868..31182)
                     /locus_tag="LP345_000732"
     CDS             complement(30868..31182)
                     /locus_tag="LP345_000732"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759537.1"
                     /translation="MGEVLYRVSSAAGEISPDFAVRRLYEWINKVEYYTKGSYVFRRI
                     ERETLFVTRNQIVLTKEDILRFRQVYRLCKEKNIQLRLAILQCFAPEQYKELQEKEDS
                     LV"
     gene            complement(31309..32502)
                     /locus_tag="LP345_000733"
                     /pseudo
     CDS             complement(31309..32502)
                     /locus_tag="LP345_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            complement(32692..33048)
                     /locus_tag="LP345_000734"
     CDS             complement(32692..33048)
                     /locus_tag="LP345_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759538.1"
                     /translation="MNLDKTNQTLREIMVCCQNIQQLIEYFGDNPTIFIQTNEYICAV
                     IGQCMFLRDLVRFSLPYQWKQDHQEVVWIRVVRICNMCAHPYKNRLNLFRLWFFIKCD
                     IPVLVAFCQKFLAQEK"
     gene            complement(33114..33566)
                     /locus_tag="LP345_000735"
     CDS             complement(33114..33566)
                     /locus_tag="LP345_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759539.1"
                     /translation="MGLKFPNNYDITEALDETCIGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNSNPKQSQEKGLDQKQPSADSKEKEKK"
     gene            complement(33568..33933)
                     /locus_tag="LP345_000736"
     CDS             complement(33568..33933)
                     /locus_tag="LP345_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759540.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIEEVL"
     gene            complement(33950..34204)
                     /locus_tag="LP345_000737"
     CDS             complement(33950..34204)
                     /locus_tag="LP345_000737"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759541.1"
                     /translation="MEKELLLGFYRKENNGGKKNMEKKNINICFLSGKECTYEECTDI
                     SVHERDGMLIVDMSPSDEPFVVKHYFPLCNIESFRIDCEF"
     gene            complement(35122..39417)
                     /locus_tag="LP345_000738"
     CDS             complement(35122..39417)
                     /locus_tag="LP345_000738"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBL1759542.1"
                     /translation="MYAKTKMNWLKALALVALSQFCFLVGTAQAHAEETTATQPTVEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPVT
                     SQPVEETASITTPASETSTPEGEKAAEATPSVKPESSEKQAEEKQRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKLNKESTASIEDQKKKEQDIPKTGTPTLLVTVP
                     TNRSVRVRRATNTAVLGGRKIDWGENIGVTSSPNNPNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALENYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLLNNFDVRATFHNQTHTIKIGETLKVKSGNDFLQRV
                     KGIQKPKGINVSIHGNEAWITVTKEAPEKAKIHFNQIEVLGTPLAYRRPGAQTIGILN
                     PFEPGDSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KNMNGKVQAEIKDLDPGKYVLKEIKAPKGYALSDETIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKIANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKERYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVT
                     FTLYNGKGQAIGKYTTDQNGEILVKGLVANNYYFTENVPLESFQPNTGKQAFTITFRQ
                     NAPDDGETLLVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQEGKEITSILTFIADKANGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAVHVDINDDNQSVRVNNPTVHTTAVFEDGLTIADPTGLFTLNDTVEINE
                     ILPGKAYLVKGILMDKATGEALLVHGQPVESAVGFIAKAENETVIVPFTFDLTGLNGR
                     EMVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLIVGKTYTVNGVLMDKVTEKPVLVDGKEVSSTLTFVAETTDGTVNLDFILD
                     AHALRSKEVVVFEDLFREGVLLASHADITDKDQTIKIVSPTITTKATNANGGKEILAL
                     PNQKVVEWVQVNGLAIGQIYKLIVQGYLTPDGTPFEGTHAEKVFMADKEMMEFLFEFI
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQFVEAPKPPQPVK
                     PNEPQPVKEVKQAAMVPMLPKTGSEDNVLWIMIGMIFVLAAGLIGYDLYKVRD"
     gene            complement(39564..39803)
                     /locus_tag="LP345_000739"
     CDS             complement(39564..39803)
                     /locus_tag="LP345_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759543.1"
                     /translation="MIDISIPEDLKPDPATIGNSGMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMIFGDGEVANKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(39893..40165)
                     /locus_tag="LP345_000740"
     CDS             complement(39893..40165)
                     /locus_tag="LP345_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759544.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(40248..40499)
                     /locus_tag="LP345_000741"
     CDS             complement(40248..40499)
                     /locus_tag="LP345_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759545.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFVESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(41497..42408)
                     /locus_tag="LP345_000742"
     CDS             complement(41497..42408)
                     /locus_tag="LP345_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759546.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGQLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEISKESNRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFNKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(42605..44440)
                     /gene="lepA"
                     /locus_tag="LP345_000743"
     CDS             complement(42605..44440)
                     /gene="lepA"
                     /locus_tag="LP345_000743"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBL1759547.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            44587..45807
                     /locus_tag="LP345_000744"
     CDS             44587..45807
                     /locus_tag="LP345_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1759548.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            45827..46321
                     /locus_tag="LP345_000745"
     CDS             45827..46321
                     /locus_tag="LP345_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL1759549.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            46299..46985
                     /locus_tag="LP345_000746"
     CDS             46299..46985
                     /locus_tag="LP345_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759550.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(47136..49745)
                     /gene="clpB"
                     /locus_tag="LP345_000747"
     CDS             complement(47136..49745)
                     /gene="clpB"
                     /locus_tag="LP345_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBL1759551.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(49996..51042)
                     /locus_tag="LP345_000748"
     CDS             complement(49996..51042)
                     /locus_tag="LP345_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBL1759552.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(51053..51325)
                     /locus_tag="LP345_000749"
     CDS             complement(51053..51325)
                     /locus_tag="LP345_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBL1759553.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(51360..52268)
                     /locus_tag="LP345_000750"
     CDS             complement(51360..52268)
                     /locus_tag="LP345_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBL1759554.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(52400..53632)
                     /gene="pepT"
                     /locus_tag="LP345_000751"
     CDS             complement(52400..53632)
                     /gene="pepT"
                     /locus_tag="LP345_000751"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBL1759555.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(53647..54768)
                     /locus_tag="LP345_000752"
     CDS             complement(53647..54768)
                     /locus_tag="LP345_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBL1759556.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(54765..55466)
                     /locus_tag="LP345_000753"
     CDS             complement(54765..55466)
                     /locus_tag="LP345_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBL1759557.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
BASE COUNT        16732 a        11501 c         8231 g        19060 t
ORIGIN      
        1 ttctctttac caacatcatt tgacaaagag cccaaatcca tgtaaacatg gtttattttt
       61 tacactgttt tcaaacaaac ccttgctatt tcttcggttc gtcctcgtcc attttcgata
      121 ccgacagcta gcttataacc caaggtatat caacataaaa aaaaaaaaaa ataggctgtg
      181 acagcagcgt gacagcaaaa aagatggaaa gttaaatatc aaacctcgta atttcatttg
      241 cgagtgcttg atttgtttct ggatataagt gtccatattt gtccaaagta gttttaatag
      301 aggcatgacc tagacgctta gatattgcat agatattttt attatgttca attaaaaagg
      361 caacatgcga gtgtcttaat ccatgcatat gaattggttt tactcctgca atttcagcta
      421 atttttttat tctgcttaaa atagttcttg gagatggcgg taatccatca aaagaaaaaa
      481 ccaattctat atttttccca attgattgtt gagttttttt ccatgttttt aaatcttcaa
      541 cggtttgtct gtctaacgaa attatccgaa tacttgatgt attttttgtt tcagcaaatt
      601 cataatcttg tcttgtacgg atgtaaattg acttatttac gctacatctg ccatttatta
      661 agtcaaagtc tttccattgt aacgctaaga gctcctcact ccttacacct gtaacaaaaa
      721 taaaacgcat caaacgttta taaaattctt cataaaaatc cccgtgataa acactattat
      781 atactttctt aaattcatca actgtccaaa attctacttg aggacgctga gtttttattt
      841 tacctatagt atctacagga ttttcttcaa taatttcaag tacaattgcc cttttaaaaa
      901 ctactctcaa cttattgaat atctgtttaa tataatttgg tgataatggt tgctcaatgc
      961 ccttttttac aacatggatt ttcgataaaa actgttgaaa ttcctgtata tgaattggtc
     1021 gaatctttac aacctgcatt tctccaaaaa aatccaatgc acgttgtaaa atatgatctg
     1081 ttttcatata tgttttttct acagttccca acttatacca aggaaaaaaa tactctcgat
     1141 aaaaatcatg aaacgttatt ccttgcagac aaattccttg tgaatcagaa aaactttgtt
     1201 ttaactcttc gagtcccctt ctagcttctc cttgagtttt gaagcctctt ctggtcactt
     1261 gaattctttt tccaaagcga tcttgtccta aagttgcaga aaaaaaccaa gtgcctcttt
     1321 ttctgtcttt ataaacattc gcaattttcc tcattttact attcctccca agaaatatgg
     1381 agaacttctt ctaaaattga aataggaatt ctttttattt ttgaattacg ataaaaaaag
     1441 tatcctttct caactaaaag ttctttacat tccttgaaga ttttattagc atagtactga
     1501 gaaaaaccta gattaatcaa atcttttcga gtagctgttt tcattatagc accttcctta
     1561 ctttttttca tttatttcta tcagctgctt ttgtcaaaag cacataggaa tttcacctct
     1621 ccccaagttt acggcgagcc ttacggaagt atcattatcc caactttaaa tcatcgcttt
     1681 ttattgacta taaaaattat tttagaatat ttatcgctcc ttctttacag caagaaatca
     1741 tggcgcaact aaaatatgct ccttaaagtg ttaacgtact gatagaatct atttaatttt
     1801 caatgaacaa taggttttct acctaaaaga atctactaat tccttaacta ttagaagatt
     1861 cttttaaaca gaaaaagtgg aaaggagatt tttttaatta gttaatttta aattttaaga
     1921 tcgcttctat taatttaatt tctagctgac ttatcatata ttcatctaca taggtaacga
     1981 attgacctac ctcgttaaat ccatttgtca aacataactt agccatataa ctatgataat
     2041 gtttgagtat catcttgatc gaaattggat ctccttctag agcagataag ataatggata
     2101 gtggaactaa taggtactgc cgctttttgg atttatctac cataggtcat accccatttt
     2161 caattgttca actgccttct ttcgttgata ccagatacca cttgtgctca tattgagaat
     2221 tttaccgatt tcagcatcat taaaacctgc aaaataataa agtaggataa tctttcttct
     2281 tatctccgat aactgatcaa ttgctgctga taacttttga tctgaaatta atatttccat
     2341 tccaaataag aaatagacat cttgttcatc aaaatgagtt tgggaatacc tgccttcatt
     2401 tgaatctgcc aatggttcct cattatcctt tatgttagca tttcgttttc gaatagactt
     2461 agcttcgttt cgtaatactt ttttacagta ggcatcaaat tggtgttgta tagatatgtc
     2521 attgtaatgt tgttgcatga taatatgctc ctttttcccc ctttccacta atacaacaat
     2581 cagagagccc ctttttttcg aaaaaactag aaaaaaacat aaaaatattt atcattcttt
     2641 aaacagaaaa tctttctata aaaaacaaaa aaacgattag gctaggctaa tcgttttttg
     2701 aacattctta aaaaaatcca aattattttt tataactgaa attgggtatt gatgaccatc
     2761 gtttctgtag atagtgagca atcattttag gttttctatc tctagtaaag attcctttct
     2821 tatttccttg cactcttaaa atcccttgac tcgttgcaaa atctgcaaaa ttccacactt
     2881 gttcaccaac aaaattttca catgtatcta ttacttcgtg atttgcttcg taataagcca
     2941 cttgatactc ttctgtaaac attgttggta ctgtatcatg aaatccagct actgtatctg
     3001 ctccatattc tgtaaacatt attggcgtat caggacatct ttctttccat ccatctagct
     3061 cttttttcaa cagatatttt gcatgtgcca gatcccctcc cgaaacatac caaccataat
     3121 aacgatttaa acataaaaca tcgacaatat ctcctacctt acaaatatct ggcgttgatt
     3181 ttagataagt aactattgtt acaggtcttt tctgcggatc aagttcttta gttaattcaa
     3241 ctaaaggttc aaaatattct ttagcacctt cggaatccga atctggttca tttgcaatag
     3301 accacattac aacacttggg tggttcttgt cgcgttctat caattccttg atcaccgttt
     3361 tatgagaatt ttctgttcgt atctctttcc acgtattatg tttttccaca ttatcatcta
     3421 ataaagtggc catgaaattt aaatgtaacc ctactgcagg tacttcatca ataactacaa
     3481 taccttctcg atctgctaat cgcataattt cttctgagta aggataatgt gatgttctaa
     3541 aagaattagc acctatccat ttcattaaat taaaatcttt aatatttaca gcctcattca
     3601 aaccacgtcc attaacatac gaatcctcat gcttaccaaa tcctttaaaa taaaaaggtt
     3661 tattattaat caaaaatttg ccattggtaa cctgaacact gcgaatacca aattcttctg
     3721 tataggtatc gatcacttta ttatcatcaa ttaaactaat tttcatacta tataaataag
     3781 catctagagg ttcccaaaaa attggattct taagctgaat cattcctttc tttccttcag
     3841 cttcagctac aagttgagcc tcttcgtcat atatcgctat taagattttt ccggtccatt
     3901 ctgtatcgat attgaattct acacttgcat ccaaatcagt tattcttgta ttaatagtaa
     3961 tatcacttat atagtctttc ggagttgtat ataacttaac aggtctatga atacctgcat
     4021 aattgaagaa atcaaaatta actaagtttt ccttttttat atccccattt tcctgtactg
     4081 tttccttcat aatccccaca ggtaaagtac tatcgtcaat aatattgttt acagcaactg
     4141 taattcgatt attcccgtct tttacaaacc gattaatttc agactcaaat ggtgtaaacc
     4201 cacctttgtg ttgagtaatc aactttccat tcaaaaaaac ttttgcttca tgtgttgcag
     4261 atccaaaacg aagaactaat ctttcttcta ataatctttt aggaagagtc acttcttttt
     4321 cataccacac ccatccaaca tgatttctaa tgttctctgt ttcaaataaa tcattataag
     4381 aagagggaac tgaaatcgga taactctctt tttcatttat tggttctaaa gcaagttctt
     4441 cctgtaagtc atcatttgta tctaatttaa atctccagag accgcttaag tcaattactt
     4501 gcctcgtctc tgtcataatg ggatacaaca tataaaccac tcctatctaa atattaaata
     4561 aatgtatcct ttaaaccaca ataagcatct attggactta ctcccttaaa ttcagaaaga
     4621 cccattagtt tgtccaccaa tatttctaaa gtttcttgtt ttccatcata agtattaata
     4681 taagtcttta cttgaggtac atcagccaaa tgaaacggac actgtacaga tacaaaaatt
     4741 gttggaattt catgaatgta aaacggtata tccggagttc ctttacttgc tggccagaca
     4801 attcgttgaa ctgtgcctgg attaacatta gctatattaa tgatcaagtc atatttttta
     4861 gttaaatttt taattggtct cttagcagca tatattccag ctatattttt aattttttct
     4921 tcttgcgata atcctttcaa ctcttcttca ggtgaaatgt atttttcaac ttcaaatcct
     4981 tttgctgaca aaatctgttt caataaatca atggcttgag gtctatttcc agcaactact
     5041 tcaccaaacc caccttttac cccatgtaca tctactagta aaatcctttt atatttttct
     5101 ggttcaatag gccaaatatc ttgtttatct ttaactaatg taattgcttg gtcagccacc
     5161 tctttaaaaa ttgatttatt ttcaattaaa ccaatttttt ccagagcttc ttgcttaggt
     5221 aataaaattt gttcttttgc ttttttgtgt aatcccaatt tagcttttaa ccctaaaatt
     5281 ctttttaagg catctaataa ccgatcatca gagataattc ctttacgata accttccatc
     5341 atataattaa agtcttcatc tggatcatta aaaaatagaa atagatcaca tccagctgca
     5401 atagaagtgg gcaataattc tgatcgtttc attgccccag tcattcctaa catatgacta
     5461 gcatcagtaa ctactaatcc attaaatccg agttttcctc taagtaagtc agtgattaat
     5521 tcttttgata aagttgcagg aagtaaatct tcatctttca gatcaggatt aaaatgtttt
     5581 gaataagctg gcatatggat atgacctgcc ataatcgaag gtaatccagc ttctattaaa
     5641 cctgagtata cttttccaaa agaattatcc cattcttccg tacctaaact attaatacta
     5701 aaagatagat gctgatctcg ttcgtcaata ccgtcaccag ggaaatgttt agctgcaggc
     5761 aaaattccac tctcctgaat acctttcata taagctaaac taagttctaa aactttatca
     5821 gggttttgtc caaaagatcg actagaaatg ataggatttc tccaatttct attaatatct
     5881 acaataggag caaaactcca gttacatcca atagccgatg cttcaatccc agaaactctc
     5941 cctaattcat aagcatattt cgcatcattt gttgcaccaa tttttacttc tacaccaact
     6001 tcagtaccat ctgtacaagc tccgttacca cctgcttccg tattagcagc aattaataaa
     6061 ggaattttgc tttctgtttg taggatatag ttttgatcat atacctcatc agcagttcct
     6121 gggttatatc gtacagctcc aatatggtac tgattgacca tattactcaa gtaattttta
     6181 tcacgactag atcccatatt aacaaacaat tgacctattt tttcttccaa agtcatagaa
     6241 tcaatcgtct cttcaatcca agaaatagca tcttcatcta aattatatgg tttttttcgt
     6301 aagtctactt ttatagtcat tttctttctc ctctacttat tagtaagatt tttccaaaaa
     6361 gtatctataa atttttgttc aatatctaca tactctcccg ataaacattt aaataaaaca
     6421 tcagttctta agttttccca tgattctttt tctttattaa ccaaaatagg ataaaagaaa
     6481 actttatttt tatttgcagc ttctagatca ccaggagaat caccaatcat taatatctta
     6541 tccaaatcac aaccattttc aattacactt cgaataatgt cttctttttt tcctttatct
     6601 tgacaacaca gttcatcaac taatgataat aattcatgtc tttcccattc ttcttgaaca
     6661 gcttccttat tagctgagct tacaataatt atcttcccat attttttcag agcttttata
     6721 gtatctctag cacttaaaaa gggtttatct aatcctttag cttgactaat ctgttgattg
     6781 acttcttccg accattttaa agcttttaat aaatcctctg actgataata ttctatttcc
     6841 ctcttcaaag atggattaga caattctttt gttagagata cccagtgctt taatcgatta
     6901 atggatgtta catcattttt ttctaatgtt ttaactaaac ctaaaaatct gtttattcca
     6961 cgagtctctg aatataaatt aatattattc caatcctgta ggaatttttc tctatgatga
     7021 acatcaaaaa tctctgcagc aattggtccg aaaaagagat tgtgtttata agtcatcgta
     7081 tccataacac agccatctga atcaatacaa aatatccaat tattcatatt tctctcctat
     7141 ttatattttt gttttaaaag ctcgcaattt tctaagactt tatctttaga taatggataa
     7201 aggaaaaata aaattaatcc tacaataaaa aaacaaattg atggaattaa tgttgaagcg
     7261 ttatataact tttctaaaac atctcccgtt tgtatatttg ctaaagagtc atagcctata
     7321 atagaaagag tccaacctcc gacgcctcca gctagagctt gacctatttt tctagcaaaa
     7381 gaatataccg catatacggt cccatcttct ctttgatcag actttacttc ttgatcatca
     7441 ataacatcag taatatttgc ccaaataaca gtattaaaca cacccaaacc catatagcca
     7501 accgaactaa gaattaagaa tacatacata ttactagttt ttatcaaaaa taagatcaaa
     7561 tatactattg ctgaaaagaa cattcctact gatgccagtt ctttttttcc atatttttta
     7621 cttaaaaaca aagttaaagg tgaaacaact attaaaacca aaataggatt gataaaattc
     7681 attaaaacta ttccctgtgc atcattatag taatcaggaa atacataatt attcatactc
     7741 ataattaata attgagcaag gagtaagaaa atagccgcac caattataga aagtaatgcc
     7801 ctatttttaa ctaacccttt taaagatttt aacaatgaaa ctttgaattg agattggtca
     7861 attcttactc gttcagtagt tagtttataa catattaaat aacaaataag tgcacatatc
     7921 gaaaatattc ccgcaacaat tgtaaaagtt gatccaccac gaactatttg agcgcctgaa
     7981 tcatctcttg tataaataaa taatggtgtt aatacaccaa tgatcaaact tgctaaagta
     8041 gctccaacat ttcggaatgt cgatagcatt gttctttctt ctgtaataga agtaatagct
     8101 gatgccattg atccataagg aatatttata gatgtgtaaa aaatactccc ccataatata
     8161 tacgtaacat acatgtatac taccttaacg ctcatagaag ctgaaatcat agaagtttga
     8221 tacattaaaa aacttgctaa agcgactgga ccactcattc ttaaaatcca cggtttaaac
     8281 ttaccctgct tagttgcttt cgatctatca acaatacgcc ccatagttac atcagtaact
     8341 gcatcgataa atcttgctac taaaaataat gttccaacgg cagctccgct tatccccaat
     8401 acttttgtat aaaagatcat taaaaaagaa ctagcaaaaa tgaaagtaaa atcgtttcca
     8461 aaatctccaa acatatatcc tattttgtct cttataccaa attttctttc catacaattc
     8521 tctcccttct tttgttaagc gttttcattc ttatgaaagt acgtactata ctctgaagcg
     8581 taaagagtca gtatttattt tttacatttc agagtattat ttgttttttc tcctaataat
     8641 tctttatctc ataaaactta tctatatatt tactagctac tcgacttact tcttcaaaat
     8701 cacctttttc aacagaagcc aataaattcc cacctacacc aactgcaaca actcctactt
     8761 caaaccaatc ttctaagttc tctagactta ctccgccagt aggcattata tttacgtgtg
     8821 gtaatggagc ttgataggct tttacaatgg atggaccaaa agcagaacct gggaatagtt
     8881 taatgatatc tacgccagca gtaagtgcct cctttatctc agtaattgtc atacaacctg
     8941 gtaaataagg aatttgatat aaattacaaa tctcagctgt ttgtcgatca aaagatggac
     9001 taacgatata ttctgcccca gccataattg cgatacgagc agtaaacgca tctaaaaccg
     9061 taccggctcc gattattaca tctttttgat cagcatattt tttagcaatt tctttgatta
     9121 tttcttcagc attaggaact gtaaaagtta gttcaatccc tttaattcca cccgcaataa
     9181 ttgaatttat tgctttaatg gcctcatcct tatttttccc acgtacaacc gcaatcactc
     9241 cagccgcttc taacttactt aaaatttcta cttttttcat atctatctcc tctatctcct
     9301 tcttttatgg atacatactt tgtctagctg tactaactta aaaagaataa atttaagctt
     9361 ttatttcaag tattattttc tacttccgat ttcaaaaaaa ttaaaataat tatacgcatt
     9421 acgataacaa atattctcca ctatctgact aagatacatt tcatcatctg gaattcggcc
     9481 tgctttaacc cactcgctta gtaattgaca taatactcga cgaaaatact catggcgagg
     9541 atagcttaga aaacttcgag aatcagtcaa catacctgta aaattcgaca acaaactttg
     9601 ttgcgccatc gtagtcaact gttgacgcat tccttcagct gtatcattga accaccaagc
     9661 acatcccaat tggatttttt gaatcatacc cccttggaag ctttgcattg ctgttgctag
     9721 tggaagccaa tcagttggat ttaatgaata taaaattgtt tttggtaagc acccactctt
     9781 ttcagcggta tcgaacaatg ctacaacatt ttgtgtcaaa ctagcttgat cccccatcga
     9841 atcaccaccg acatctactc caatttgttc ctttaatata cttgaattat ttcttaaagc
     9901 atttaaatgc atttgcatcg tccaaccata tcttgtatac tcagacatca aatgtaattg
     9961 aatacctgta acaaattgtg caatttctga taaatggaaa tccgtttttc ctgctaaagc
    10021 ttttattaac agattgtcga gtattttttc atctgctatt tcataaaaat aagtattcaa
    10081 accgtgatct gctaatcgac agccaatttg atgaaaatga tccactcgtt ggctcaatgc
    10141 ttgcttcaac ccattaaagt ctttgattgg tatagccgct gcttgactaa gttttaaaat
    10201 atagttcgaa aagcctgatg atttgatact ccagacctta tctggacgga aagtaggtaa
    10261 taccttgaaa gaattatcct gtttagaaag ctcagtatga taccccaagt catctgtagg
    10321 atcatccgtt gtacagatgg ctttcacatc catcatctcc aacaattctt tcgggcgata
    10381 ggaatccgtt tggatttttt cgttagcacg tcgccaaatt tctggtgcat tcttctcaga
    10441 aattgtcaaa tcaatatcaa agtaacgttg taattccaaa tgagaccatt caaaaatagg
    10501 attacctggc gccttctcca ctgtttttac aaaagctaaa aatttttcat aatcatcacc
    10561 tggaccactg atcaactctt cttctatacc attagctcgc atcaatcgcc atttataatg
    10621 atctccagct cctttatcat ttaaccatac ctgagtcaaa ttcttgtatt gcttattttc
    10681 tagcaaatat gctgggtcta aatgacaatg atagtcgata attggttggt gttttgcaaa
    10741 tttatgaaaa agtcttttag ctatttcatt ctctaataaa aagttcttat ctaaaaacat
    10801 atttaaacac tcctttcctt ccgttagttt ttagaagaga aaatttttcc tctaaataaa
    10861 ctccattata taattattta ctcgccccct tttcaagcgc ttcccaaata ccatttaaat
    10921 aaactgcacc tagagctcgg tcatataatc cataaccagg tctaccggtt tctccccaaa
    10981 tcatccgacc atgatctgga cgaatatagc cattaaatcc attatcgtac attgttttta
    11041 atatcttata catatctaga gaaccatatt ctgatttatg cggcgcttcg taaaaatcga
    11101 gtccattgtc acttaaatat ttgatattac gaacatgtgc aaaaggaatc cgatcccgtt
    11161 gacaaaattc agatagaatt tcatagacat cattatctgg tcgttctgca atacttccag
    11221 tacataatgt aataccatta gaaggagaat ccactacatt acacaaccaa tctaaatcgt
    11281 cacgattttt aacaatacga ggtaatccga aaatggaata tggtggatca tctgggtgaa
    11341 ctgccatttt aatcccaact tcttcacatg tcgggataat tgctttgaga aaatatgcaa
    11401 agttctctcg taatttctct tcatcaactt ctttataggc ttctaataat tgcttaattt
    11461 gtgataaccg atgaggttcc caacccggca attcaaaatt attagtagaa ttttctactt
    11521 ttctaataat ttcctccgga tcagtaggga tattttttga aatataggct aacgtagaag
    11581 acccatcatc taaacgataa tccaaatccg attttaccca atcaaatact ggcataaaat
    11641 tataacagat aacctcaatc ccaaattctg ccaaattgcg aatcgtctgt ttataattct
    11701 caatgtattg atctcgtgtt tgtaaaccaa ttttgatatc atcatgaaca ttaacactct
    11761 caataacttt caaggtaagt ccattggctt cgacttcatc ttttaaagat ttaattcgtt
    11821 ctctcggcca aacctctccg gctggtatat ccattaatgt tccaacaatt cctttcattg
    11881 ctgggatctg acgaatttct tgtagtgaga ttttttcttc atttgcccca taccatctaa
    11941 aagtcatttc catagttact ttcctccaac ttctgttata tatttattga ttgttttacg
    12001 aactgcttga ggacctacta gcatttcgca aaagattttt tcagttttct ttcctacccc
    12061 aacttgatat aaatctaaac caaaaatttc tttattttct aaaatttcct gtaccgcaca
    12121 atgaatattt gaaggatctt gttcacctaa tttcaatact gataatttat cctgcaactc
    12181 taccaataac ggatcaggac ttggcacaaa attttcccct tgatcatcga ctgccagtaa
    12241 ataacgtaac caagcagcaa tagcgatagg aataaatgtt agattttctg catttccgtc
    12301 tttttcgaca tactttttaa ttgtttcacc atagcgaatc gctacttttt gagaagtatc
    12361 tgttgcaatt cgttgtggtg tatctggaat atagggatta ggcaaacgtt tattaattac
    12421 ttcatcaata aattgttttg gatcaataat gcctggattt tcaactactg gtaaaccttc
    12481 taaataacct attcctttga ttaaaccaac caaatcatca tcctgcatct ctgctgaaat
    12541 tgattgatat cctagcagac aacctgttac tgccaaagca gtatgaagtg gattcaagct
    12601 tgtcgtaacc ttcatgatgt ctgctttatc aaccgtctct ctatctgtca taatcacacc
    12661 agccttttcc aatttaggcc ggccatttgg aaaactatct tcaataacta aataatgaac
    12721 tacctcagta ttagtgaaag cagcaatatt ggtatgtttt tttgtgtgaa tgatatctaa
    12781 atcctcgagc cccatcatca atagatcttc ctttacattc tctgaaggat ttggcgtaat
    12841 tcgatcaatc atactccaag gaaaagtcac tttttcttta tcctttaaat aagcaataaa
    12901 tttttcagaa acatatcctt ctttttgcca agcttctgca atcgtaaaaa tactatcttg
    12961 aaaacgttga ccattctgtg agaaattatc agtagaaacc atcgcaatcg gcaactctcc
    13021 agcattaaat ctgctatata acaaggatgt tacaatactc atcgtatgtt gaggattgct
    13081 aggtccagat ttgatatcag ctttgactac cgaaaagaat tgccctttag aatcttttaa
    13141 actgtaacct ttttcagtaa tagtaaacgt tgtaaactgt aatttaggat cttcaaaata
    13201 tttaaccact ctttgatagt ccgctatatt cttcggattg caatataaac tatcagccgt
    13261 tactgccaaa agcctttttt tgagttcacc atctccactc ataacaattt ccaaaatgtc
    13321 attgttgtag tcatgataag ctttttccac tacttcttca tcaaatgttt cacacacaac
    13381 tactcctgtt tctaattcat tttgatctgc taagcattga gcaatttctg catgaaatcc
    13441 tcgataaaga tttcctccac caaaatgaag ccatactgga tgttgctggc cttcttgctt
    13501 aacttctttg acatcaaaac acggcagtag aatctgcatt tcattgaatt cttcgataga
    13561 attttgccaa tttttaatcg aaaccataat taacctcctt aaactaatat gttagttttg
    13621 atacatttta tattttaaaa cccgttgtaa ccgttgtcaa tataaaaatg gaataaactt
    13681 gctttttttc taccatatca gaattattgt attttttatt cagaaaaata aaatactcct
    13741 tctttttgga ctgattttat cgaaacttat ttttttcttt ttttcatgta ttcttttatt
    13801 tttataacta gtgtattact tcaaaatttg atattatatg gcatgaacag aattaaaata
    13861 tcagctaaaa taaaagttaa ggagcattga gtatgacaat taaaactagt ctccaaaatc
    13921 aagcttacca atctattcgc cgacaaatta tctatgctga cttagaacct ggaaaaaaag
    13981 tatcagaaaa aaaattagaa gaaacacttt ctattggtcg tacaccaata cgtgaagcac
    14041 tgattcaact ccgacaacat ggtcttgttg atacaattcc tcaaagcgga aattatatct
    14101 cattaattga tttagattcg gccaaaaatg ctcgatttgt cagagaacat ttggaacgac
    14161 aaattatgtt agagtgttgt gccaaaatta ataaccaaaa aaaacggatt ttagaaacta
    14221 taatttcaga acaagaaaaa gctgttagtc aaaaaaatgc tcgtagtttt tttcataatg
    14281 ataatttatt ccataaagct tgttttgaaa ttgcagagcg agaagaagta tggcaatggt
    14341 tagaaaataa caatacacac ttagaacgat ttcgttggct acgagtaaaa acggaaggat
    14401 taaagtggga aaaaattatg gaacaacatt atcaactatt tgaggcatta acaaaacaag
    14461 atccagaaga agctaacttt ctaacatcgt tgcatcttca tttaatgctt aatgagcaaa
    14521 atattgtttt agctactcat ccaaaatatt tcaaaagtat ataactttta actcttttta
    14581 aattaaatga ttgttctgat cagaaaaata tcgcttgttt tcttattatg taatatattt
    14641 cataaactat tctgcataac aactattgtt tgtacttttt acattggata actaattatg
    14701 actgctgata acttttgata ttaaactagt atctccaatc caaataaaaa atagatatct
    14761 tgttcatcaa aattagttca tggatactta ccttcattta catcattcag cggtttctca
    14821 ttttctttta ttctattatt tcattttcta atagacttgg cttcatttcg caatactttt
    14881 ttacaatagg catcaaattg gtgttgttta gatatttagt tgtagttttg tgacatgata
    14941 agtatgctcc tttttgtctt ttccactaat acaacgatca aagggtgctt ttttcaaaaa
    15001 actagaaaaa tcaaaataag attcgtattt tgattctata tatcctgttt caactacatc
    15061 ttatatttca taatagaata aatagccttt tgcatagctg cttaacttat aagaaattgc
    15121 aatttacttc ttcaaagtga aaacgaatat gagtaaaata aaattattct tcttacagat
    15181 aattaaaaat agcgcgtaac aaaaatcggc attcaatcac ataattagga ttgatgccga
    15241 ttacttatat tctacgtata gttttagtat tcttttttta tcaccagtaa ccaattgaga
    15301 acagtcctaa agcagaatag tcttttatct caaaacgctt aatttcaggc ttaggaatat
    15361 gaataatctt ttgagtatat tctttctctt ttaatcttac tgaagaaata ccactgccta
    15421 tcttttttac aaatatttca tttggtgtac agactaataa aacaatattt gtaatcaatc
    15481 cttgcactaa agaattaaaa ggaagactat ttaaaacagg gtgtgcataa ctataacatg
    15541 tgaagtagtt attttgaact ttaactttta aaaactttaa aaataatctt atttgttctt
    15601 ctaaacaatc atctatactc atataatcac tccactaatt acttccccca acaagaaata
    15661 gcattaatag ctataccagc tgcaatagtt gcagcattga attttgcaaa ttgtgcagga
    15721 gttaaacttc tttttgctac atctaaaagt attttaacag cataatcata atttttccct
    15781 tgcaacgcat taattaaagt ttgcattaga ttttcacgat taagtatatc ccaaacaaca
    15841 caccaaatgg taatgagttc ataacaacac atgcagcata cttttgaaga tcacgttttt
    15901 gacgctttcc tgttggctgc acaaaatttt ctaaaataaa tttccctgct ataccttcag
    15961 agccatctaa ttcagctttt ttctgtatag cttctaaatc agtaactata tattgatgtg
    16021 tttctgtatc aacataacca gcttcttcta aatagaattt caaactctct actgcctgtt
    16081 gtctttgtgt ttctatatca ggaacttcat tcactttttc agcagcataa acactggttc
    16141 cggcaccgac taacgtactt aatccaatta acattacacc taataatgaa aaaaacttaa
    16201 aaaaacgact catttttatc cctcctgaaa agtattgttg attatcaatt tttatccttt
    16261 taagctgttc aataagacgt ttttacgttc cttccgtttc tattttattc tttctgtctt
    16321 ataacagctt ttttcaagta aagaacgata taattcttct taaaaaacag tctatttttt
    16381 cggtatataa taaaattgta ttgttaccta catagcgaaa cagtaccaac atcattcaaa
    16441 tgaagatagc aaatttgctt cttccttttt cttaagtgac tatttaaata accagaaaaa
    16501 aactaaaatc acactgatat cccaaataaa ttgaaataaa ggaaaaagtt tttttctacc
    16561 atgatagttt ttcaaaaaat agaaactcgt actatttaaa agtaaaataa ctagcatcgt
    16621 aaagactact gatttatcta aacttctata aaaaagtggg ctaaataata aagtaattaa
    16681 aaaatgaact atttgatatt gttttttttc atattaacag atcgcagctc ctgcgattcc
    16741 ataggctgtt cctacagcaa atggaataac ggctgcacct actcccgtaa ggcttaaacc
    16801 tagagcagca gctgtataaa tcccagaatg tagaagtcca gccccagtga aagcccaact
    16861 gcaggcactt cgttcaccag ttttattatt tgttttttga tctttcatat aattctcaac
    16921 ttcatgaagc tgatcggtta gccatccatg gccatttttt ttgaatagaa cgattaaatt
    16981 catttagata ctgttggatt tcagaaactg taatttcaga attaattcta tctaaacttg
    17041 attttaaatc actctcatca ataatatata ctaatcgatt tcctttagaa tctttatgtg
    17101 tggctaaatt attttgaatg atatttattt cagtttcttg ttgttttact aaaaaattat
    17161 ttgtttcaga agcatcgaca cttattccag cgctaacaaa agtacttaaa cctattaaga
    17221 aaacacctaa aataccaaat attttaacta ttcttttcat aatttttcct acttaaaaat
    17281 aagttatttt taaaatatct tgattatgaa ttcatccccc aaaggccttt taagattgat
    17341 acagcagtcc gttcacttct tttagacttg tcatataagt cttttaaatg atcccatacc
    17401 agactagttt gtctatctag cttcaatcca ttaaacgcta atgaacggtt cattttttct
    17461 attactttag ataaagctac agaaattttt ataccttcac aacgcgcatc ttggatttca
    17521 ataatagtat catcaattag tttttgaatt tctttcctat caacatattc aatcttagaa
    17581 agagaatctt ttaaagctac taatgattca acgatttctt ttttctcttc agacattctc
    17641 ttcctccttc tagtgacccg taaagccatg tagagcagag tccattgaac cagtaattac
    17701 actatctaca acgccattcc aatttactct acattttcca tttttcagat ttgtcggtcc
    17761 atacggatag actttttgac attcaatgtt cggattatac cagataggat tataccattc
    17821 agccgcagaa gcagattcag tcgatacaaa caatcccaca ccaacaaaac caatacacat
    17881 cacactatag ccaattaatt ttttcatctc gtatccatct cctaaaaaat agaatagttc
    17941 ttgtagttat tcataagaca tattttttcc gtttttgttt tatcctttct gtcctataac
    18001 aacttttttc aagtaaagaa tgacatactt cttcttaaaa aaacagtctg tttttttcta
    18061 ttttttcggt gcataataaa tatgagtgtt cattttttat tttaatacac acttcgtaca
    18121 taataaatct tgatcgcatc aatcttttga gcttcttgat ctactttcaa ttgaagtaat
    18181 acaaattgag tgacctcatt cgttgtttct tctccaaata acaaatattg atccggattc
    18241 tctatatctt gtgtcacctg gtgaagtttc ccagttgttt tcatttgtac atgcgggtct
    18301 acatcaatac tattgtcttt aatacaacga tccgtcatat agtccctcac agcttgattg
    18361 cgtttataaa catctgtgaa attactccat tttctagcaa aatcttttaa gaaatttttt
    18421 gtcatttcat ctatttgttg cgctgtctcg tcttctaatg aaccaatttg actgttactt
    18481 tcagtacttt gaagagttcc acttgtttct tttactgctt cgattgtttc ttctgtcgtt
    18541 gtcaattgtg ttttttgttt ttcagaagaa aaccaatgac aaccagtaag acctatcaaa
    18601 cataaccaac taaatactaa aattattcct tttttcacgc ttctagacac tgcctttctt
    18661 atttcacctt acgaaccaga ctacgaattt ttgtttgatt gtacgtgcgt tgataccgag
    18721 ccataatccg tccttgctcg gcattctgtt ccacactaga gaaatgttgt ccgccatctg
    18781 aaacatctgt tataattccg gtgtgaccat agattccagg agacaatgca ccacctgctt
    18841 gccaattcac cacatctcct gcttgtaaat cacttggttt tgggttcatg atcacttgcc
    18901 aaccataggc tgtccaatca taatcttccc ctattaacat cgcaaacatg tgtccagaac
    18961 ccattaactg tgggccacct agttgggata cataccacgc cgtgccacca taacactctc
    19021 cattatttac cgatcgtcca atgatccgat ctaaaacttt cgcattacct ttacttttcc
    19081 ctgcaacaag tgacgatttt tttgttggta ggctattcca atgtttgatc gcaaaagtat
    19141 catattctgt taagttataa gactttatga tactcatcgc tccttggtaa tacggactgc
    19201 cttcggtaat acctgccgcc gcatagcctc cacgacctag aatcaataaa caactcccag
    19261 gatctttatt gcccacacat tgattaaagt tgctttgact cgccaccaaa aagccgtaat
    19321 agtcataaca atctttcagg ttcggaaact tcatatagaa gccaccttca gaaccaccaa
    19381 tcccccgtgc agaaccttgt ggatagggac aaccaggaaa ccaggtaatc ccaaagaagt
    19441 ttgtatcgtt tcttccagat tgtgattgtc cataagtcga ttcataacct aattgagaaa
    19501 gaatcacact tggtaataac tgatacttta ccgctgcacc gactgctgct tgcgcatgtt
    19561 catctgtgat cggaccacgt cctttaatct ctgaaaaaat cggtaatcct tcggtatatt
    19621 cccaattaaa agcgacagct agacctgtag cctctcctcc atcctcggaa agttctcctg
    19681 aaaaaaagaa tggcaataga aaaaagggaa gaataaagaa aagcagacaa cctagacacc
    19741 ctttcttcat ttcttcctca tcctttcttc gataatggtt tttgaactgt tcgtcctttt
    19801 ggtaaagtaa aatcggttcc tggttttgcg tccaaaatcg gcaatgtttc atttttcttt
    19861 tctatttttt tcgattgctc tactggatta ttaaaagaag aaaatgcagg ttgtaaggat
    19921 tttggtacgg aaatcgacgg tttactttca gacgaacgtt gtatctgtcg ttgcacagaa
    19981 cgatttcctg atagagtggc taccgacgac ttaggaacag agtattgatt caataactgc
    20041 tgcattgctg gataactccc atttttcgcc tgatttttca cttggtgaat ctgttgtgaa
    20101 agagaaccag cagctgttaa ttgtggcacg ggtacttttc cagcaggcaa cggaatcgat
    20161 tgaccaacaa aagcgatacc tttatttaac aatggttttc tttgattatt cccttgttgc
    20221 ttactcgatt gtgccaacga ttgtacctgt tgtttcggtc ttactgaatt catggacgaa
    20281 tttggaatca aaccatttga aagaccagaa ttccactctg tttttgattt ggtagaagac
    20341 atttcaggct ctaccccatg ataacgaaca tgacgaccac tataaggcaa gtcttgattt
    20401 gaacgcccac ctagttcaaa gggattaatc acttgccccc cttttaccga ttcttgtggt
    20461 gtacgttttt gttgaaactt ttgaaatcca tgtatcgctg cagaagcgag tggattcgtt
    20521 gctcggtaca cattccctgc taatcctgca cctttgattg ccaaattttg cccagcagtt
    20581 gatagttgac caggcagttg tttcatttga gacaaagaat gacttgctat gtttttcgtg
    20641 ttatttatgg tttgatctgc agctcctaac cctagtttct ttaataaatc tttccgtttt
    20701 acaatgagta aaattgatag gagtgctttg acaaacatat ttcctaaaaa accaaaaaca
    20761 gtattcatta gaattaaatc gtctactatg ttatagatca aaaatgccac caaaataatc
    20821 acactgtaaa aagatttttg aaacatcaag ctcaaaaagg actttaaggt attcatgatc
    20881 atataatcaa atgctggaac aaaagaagcg agtaatgaaa aaggaatcac aagtaataaa
    20941 cacaacacca acatttgaaa gataaaacga atcatgccaa tcactacaag tggtaatcca
    21001 atacttagat taagcaatgg caccatagaa ccaacgactg ctttataaac agctttagtt
    21061 ggttgaatat agacacgata agccttcttt ttccctctat cttctcctgc agcagtggtc
    21121 acttttgtct caatatcaga taattcttca cttgacgctt ccttggctag aaattcttgt
    21181 ggttcaatct ctgcttgata caattcttct aaatttgttg tcccataatt taacaataga
    21241 tacggatcaa caacagccgc tttataataa agttggcgca ctttttgaat ggcttccttt
    21301 tgtgtcgttg gcactaaaac accattgaca tcttttgtcg ccaattcatc tagactattt
    21361 gtagcagaaa aaataaagcc ttctacctcc acggacaaat catttaaccc tttagtaaaa
    21421 gcttctcctt tactaggtac gttactacca tagccaaacc aaaccattga aaaaatgaca
    21481 acaaagagaa atcgaataaa caccattttt gcgtaatgtt tccctctaaa tatacgaaga
    21541 gtaaatagat ataacacata caagacgaca atccccgcac caataggatc gtatattttc
    21601 gaataaatag tatccgaaaa agtgaaaaac tggtgaatta actcgttcat tgcagctcct
    21661 tcatagagct tctcaatgac aaaatcaagg ccttgccaaa tcaatttact taaactaaag
    21721 aacatattcg tcatcatttt tagaaaatct gtgccatttg ctccaaataa cattttgcct
    21781 aatgaaaatt cactatcaga taaataagaa gaaaaggtat caatatgaaa tttcccgatc
    21841 tcatagatcg attgatccac ctgtttttct accgcatata ccaatccacc aacaaaaaac
    21901 agtccgaatc caaccgttaa aaaaagccaa acgcaccatt tcttttcctt acgctttata
    21961 taagccattg tttcacctcg tttctattgc atgattaacg tatcctgttc ttctatttga
    22021 gagtgacttg ttttttccgt tgtttgtaat gcagcggtca tttcttcaaa caaactgtgt
    22081 acattgagtt ttcctacacg tccataggga tctaacatcc aacactgtcc tttaatcata
    22141 tggctcattt cagataagtt cgcttcattt acttccaaac gtaaatgagt caaaatcttt
    22201 tctcgctcac tgtcttcatc aaaagcgaag acaacaccaa aattcccttt ttctttatct
    22261 gaacctaagt cgccaataaa ttgtgtatct agcactaatt gattcatctg tgaacgcccc
    22321 acacgcgcca ttgctgcaat aatactacgt cccgcgttcg aattattaaa tacccatgct
    22381 tctgtaaaat aaatcgctgt tttcttacta ctatctcgtt ttccaaacat ttcacaaaaa
    22441 cgacctaaac taatcatcaa acacaaagac tttcgatccg catctgtata tagttctggt
    22501 cggacattgt catttggtaa tttcaaatct tggatctcta aaatcgttgt tttggcatta
    22561 aagtctaatc ccgggttttc tccataagaa aatcctaaac gtaaaatcga atcttctacc
    22621 gtcaagcgta aaaactcacc atattctcga acctcttttt gttccatttg ttctaaatac
    22681 tcgaccacat gcatcaagcc aacttgttgt ccggcttctt tttgaactaa aacttcttgg
    22741 attcccttta ataccgcccc ttttaaaagg tgattggtac ctaacggact taactcatca
    22801 atcatatcct gggctacttg tttcgcatct actcgggata aacaaacaat tggatctaat
    22861 acgccataat tacggggatt tgtagcatct aacgtgacat aactcatttt ttgcaaatgt
    22921 tccacaaaca aagggtaatg tttctgataa tacgggtctt gaatgagttt cgtaaaccat
    22981 ttgcgctttt ctcctttggg atccacaaat aaactttgta cattcataaa cgaactatac
    23041 aaaaagagca atccaactaa aaaggtcttc cctttaccgg tttttccagt tactgctaca
    23101 tgaggcgcat caaacaacgc acctttgatt ccttccgcaa tagctagaag attcaaaaag
    23161 acaaaacgat ttgacgcata aattaattct tctaatggtg ttttttctcc tcgagaacca
    23221 ccatccccta atgtatcttg ccgaccaata taccagccgg attccatacc taattctgat
    23281 actgctgaaa acaaccattc gccaattgct tctacagttg ttcggtgctt ccaatgcaac
    23341 tgtcgaccca atggttgccc taataaacat ttatagaaca attctcgttg atcatttttt
    23401 gcacggtgga tatggatagt cgtatgaagc tgttgaataa tcgttgcact attttgacga
    23461 acttcttcaa ccgtttgacc gtatacaata aaacatgcga tccaatcgac gacaggttgg
    23521 ccattatcta ctcgttgctt taaatgtttt actaatcccc gaacagttaa taagcgttcg
    23581 ctaggttctt catcgttttg aaccaattcc ttatattctg ttttgaaccg ttccgatagc
    23641 caatttagtt ttaaaccaat acctccctgt cctttcaagc gtggatagtg aattttcatt
    23701 cgtaattctg ctgggaaaga aagatcctgt gcaaattgaa atagatcaca gtttctcata
    23761 ttttcaggtg tttctccaat aggtaacaac gctaaataac tagtgcccaa ctcatcttct
    23821 aattgaagaa ggcctttatg ttccttcggc atacgtacat acgttccttg attgtctttc
    23881 agtacttccc aattattttg ttcttctact ttatgagcca ttcctcgaat atattgcaga
    23941 cgattgagat acaacagctc tttttttact aagggacgaa tagaaaagct ataaagtaat
    24001 tgtgtcactt cttttacata aggatcactt tcagaaaaca aagtttctaa atcatctact
    24061 tctaatccaa ataagcgtgc taaacttcct gctacatcta accagattag atttagtaca
    24121 tcataaaaac tctccacggt tgctttttct ttgactttga ttcctaaaat aaaggaagga
    24181 cgatagactt gaccttctcg ttccaacaat gtcactgttt cttttgcata atacgcacca
    24241 attgcttgac tatcgggaga aaatcccttt cctaatgtgt caaatttcgt ccgtaaattc
    24301 attgttcgtg gatacatcac caactccaca tcttcataat ctgctaaaag taacagtaaa
    24361 cgagccatca tttcttttat ttcctgtgtc ttttttggtg tgttttttga aatggttcgt
    24421 ggaaaaacat gatagtaggc ccagatacaa tcctcgccat ttaacaaaca atttttcttt
    24481 aatgctttca ctggttcttt tacaagtacc aatagatctc acctcccaat taaaaaaagg
    24541 aacaaccagt tgattgtccc tttttctaat cctctaaata aacatactta ttcgcaaaaa
    24601 gtaattcttc caatgcatta tttgatacct tgtcccagtt ataatacaca caatcaccat
    24661 tcatcatacg cactacataa caaaaccaat cccataaata aaaatgcact ttttttccat
    24721 caggttttag ttttgccagt gctaacacac ataaataggg tagccctata aaaaaaacaa
    24781 cccctgctgg tggaaaaaaa gaaataaccc aaccaataaa tgaacgtaaa aataaatatt
    24841 caaagattac gaccaataaa aaagttgctg cattgactaa tgcaactgga aatggaagac
    24901 gccaattgct tgtaatctgt tgtacgcgat aaggctccgc ataaacaatc gaataatcgt
    24961 aaggttccca atccacttca ctatcctcct aatccataaa taatttttca atgattttac
    25021 caaacgcatc aaatacacgc gttggatcat ttaagaagaa atagactgcg gcacctgctg
    25081 cgatagatat taatgcattt cctacttttg atttcataaa atttcgcaat cccagataaa
    25141 caaccaccat tattaaaaaa tagccacctt gcgttaatat aaaatctaca attcccttca
    25201 gtgtcatttc cgttcgtctc ctttcctatc caaccaatta tgtgtgagtt tttcaacata
    25261 atactgattt gtttttttcg taataacaag cgtcatttgt tctttttgta aaagtgacgt
    25321 atcaccatct cgaaagacga ctgttgcttt tacaataaaa gtttttttcg tttctttata
    25381 acgcaatact ttcatctcta cttgatcaac tttagctgtc tgattgagtc cttcaggttc
    25441 tttcatcatg tatgacatat cttttgcatt gtttttcgca tacttatcta agaaatcttc
    25501 cacaaatcct tccacatctt tcgcttccga cgcatcaacc gtttcgtata atgtgtcatc
    25561 ataagtaatc attcgttgtt tttctgtatt ctttggtagt gccgtaaaat aaggataagc
    25621 aataatacga cagcccttgt ttgaaataga aaagggaaga ttgagtactt gtgtgattgt
    25681 cacacttgtt tctttcttat tctctggatc catcgagcga atatcataag ttactttata
    25741 actagctgtt ggaatggttt caatttcttt taatccaata aacgaagcag cagttaattt
    25801 tcgaatacct gaaacacttc ctggttcttg aataaagttt tgtgcataaa actctttttt
    25861 taatatttct tgacgttgtt gttcttgttc atgattatcg aatgtattca tatacaaagc
    25921 aacaaaacga ttcataaagg attcaatttc aggtgtgtac gttaattctg actgactttg
    25981 tacttctttc ttttgtaatt gttggatttc atctttcaaa aacgacactt gaaccttcgt
    26041 tttcatggat tgaaaaaatg ccaagccccc tgaaaaacaa agaaataaaa ccaaacacca
    26101 aatccatttc actgcttttt ttgaatggat tttcctttga ttcggtactt tctctgtata
    26161 aactttttct ttccgccgta gttgtcgttt tttcataagc tactccttct agtatgtttt
    26221 tactagtacg tacgattgac aacgataagc ttgtttttct gaaaaatagt ccattcaatt
    26281 accctcattt tctattcctt ttctctttct tttatatcca acaaatccag caatacttgt
    26341 caacactcct cctagaacag aaagtacaac atgtatttct tcaccagtct ttggtaagac
    26401 ttttgttttt ccatctgctg ttttgacttc aatattgcca cttggaagtt tctttacagg
    26461 aatcgacaaa tcctttacca aattcccttc actatcttgg attaatggaa ttccatcttt
    26521 tacaccaaca attgtttgtc caccttctgc ttttagtgga gttgttggtg ttggaatatg
    26581 ggtcaattcc tctacattac tagtgacaat cggtacactc attccttgag aattattcgt
    26641 cgtaatttca ccgtttgggg ttaccgatac tgtgacttct tttgctggaa caataggttt
    26701 attttctttt ggaattgctt ctgatttttc agcaggttgt ttcggttctt cttttggttc
    26761 ttcactggta aacgacatcg ttggctgttc cgtacttgac gaatcggtat tcgtttcaga
    26821 agaactggtt gttcctgatt gttctggagt tgtgactata cttgaatccg ttgttgttga
    26881 actgtgcaca ccttcttctt caattggatc agtcggcaaa gttgattcag gaatctctgg
    26941 ttctggtgcc actggctctt tttcaggttt ctctggctgc aaatgttcag gttctgctgg
    27001 tttttccgtt gttcctccat ttagctctgt ctcaacatct gataatcctt cccctggcaa
    27061 tgtttctaca atttctgact taggtgtttc tacagtttca tctgcataaa ccaatgaact
    27121 ccctaattga aacgaaaata atgaaattcc tagtgttgtt acgactgcta atgttgtttt
    27181 tttcatgatt attcctccaa ttttttatgc aattcgtgtt ttgttcatag acgccgcact
    27241 aatattatct gaacgataaa agaactcccg tccgttttct tctaacccaa catatggatt
    27301 atttttgaat aattgaatca atagttcact ggtgttgtat tttggatagt ttgcaaaaaa
    27361 ataatactgt gcttgtcgcc catccgaaaa ttcaacaagt aattcataac gataccgctt
    27421 caatcctttt cgttgtttta aaggatctct ataccaactt gtccatcgtt ccgttcgtgg
    27481 accgagatag acacgataca catagaacaa tgccatacca cataccacca aaaataataa
    27541 tcgccacata aaaattcccc cttttcttct acctttcttg aatcaccgaa cattcatacc
    27601 ctcggtagag atccgaaaaa tccatcatta atttttcgta taaacgttgt tgcaaatagc
    27661 gattgtttcg aatacataat tcttcatagc catcaatcac ttgatcttct ttctcatagc
    27721 atcttgtagc tctatgacgc tcagcttgca tgacataacc aaactctgca ccatatcgtt
    27781 ctaccgttaa taactgttga ctacgcaata atgcaatata acaatcacaa aaatgttcag
    27841 ccgacatttg atttttctca cgtttgtgaa ataggtattc tttagaaagc acattattcg
    27901 ttaaacaatc tgataaatag cgataatctg gcggtcggtt attttcatct gtgaattttt
    27961 cccataataa actgattttt attcgttcag cggctagata gtcttgttcg cgtggataaa
    28021 attcatcaat cgtacaaagc ttttttatca cccgaataaa caaatccata taatgcgaaa
    28081 cgaactcttc cttttcaatt ggctctccta aaaattccag tgacatacca tcttctcctt
    28141 ccttaaaaaa taaaaaagca gaaaccgatt tggcttctac ttttctttcc ttttatagct
    28201 cttttttacg gaagaatccg caaatgacat tttttcaaaa aattaatcgg cacaagttca
    28261 cgaaaacttg gagcaatttt agatagaatc acttccccat cttgtaaaat acaatcataa
    28321 aaatcatcag ttacttgata cttacgcttc ttacaataat tgataaaata gtagcgatca
    28381 ttttctattt ccattcgttg ttctactaag cgcatacgaa catcatcata gaaataagcc
    28441 acaaatcgcc cttcaagttc acgtttttca atgggatact cttttggtaa caatctattt
    28501 tttcgtcgtt tatacattgc tggatacctt agaagaagtt catccaaacg tctgtcagta
    28561 tatggcaact gacgaatcaa tgattccaat cgttctttat acagatagaa taattggcgc
    28621 aagcaatagt gtactgcttc tggattttct aatactgttg gatcacgcga ccaatacgca
    28681 ccaacataaa tcataatttt tttcatttag acaatcacac cagcaatact aatcaccgat
    28741 ccacaatagg tagaacaagt ggcatagcgg ccgatttcct ctaattccag ctcaatctct
    28801 tctaaagaaa gatacgtctg ttcttctgtt ggctggcgat tcatttccca agtaacagtt
    28861 gccaacgaga tttcttccac aagaggtttt tcgttgctaa gtgctgccac acagttttcg
    28921 tatatcttca ttttatcgca gccttttttt accgctaaaa tcgcaggtac cggcaatgaa
    28981 aatcgataaa agcgaatgaa ttttagcgtt ccttttcttc ggctaaattc caactcttcg
    29041 agttcttgtt cgtacccctt acgaacttct aataagcgtg caatttcttg ccagttttct
    29101 ttttcctgat aacgtccagc ctttaccgct tgttcaatat aaggaactcg aaaacgaaaa
    29161 taagacaaat caaccatctt ttcatttaat gcttcaattg cagcctttaa atccaaaaga
    29221 cgcagccatt ctgttgtcgt atatgcattc atgcaatttt ccctcctgac gttcccatcc
    29281 attctagata gctttgttgc tcgtcattta gttcagcatt ctcaattcct tcttgtacaa
    29341 agtctcttcc taaaatacga tctgcttctt gtaataactt taatgtcgga gctacttgtt
    29401 tcaaaaacca gcgttctgaa cgatctaatg agaatttttc tggctttacg gtaaaatcca
    29461 attcttccat cgaacgaaac aattttgccc atcgttcatc aacaattcgt gcatcacttt
    29521 ccagtcgatc ccaaacaata agttttgcat taattaaacc aacgccaatc tctcctaaac
    29581 gtttagggga atgatccaaa ataaacgctt ctactgcttg tgttgctttt tcattagcta
    29641 ggcgtaactc atatcgatta taaatgccat atttcgttaa tgcttctatt tctgaaattt
    29701 tctcacgatt cgcaatttca aaacgttttt cgtagaaatt gaaaaacaat ggactctttc
    29761 gcgatccaaa atacaaggat aacccttcgc ttcggaaata accatcatct aaaaaacaac
    29821 cgccaatatt ctgaaatttc ttaaagtcca tttctaataa acctgctttt tgtttttcta
    29881 gtaattcaaa gagatcaaaa tgttcttctg tttccaatcc ccaaagttca tctaacgcaa
    29941 tatcgaatcg actacattgt actcgtttat aaccagcttc caactttcct tgatttttcc
    30001 aaatggaata tagccatgtt cgccaatctg ttcgttgttc acgcatgact tcctcatatt
    30061 ctcggcaacc ttgacccgaa aactgtacaa gtacattttg tgttacagtt tgttttgaat
    30121 gccagaatac ccagatattt ccacgaacag aaagacaatc aaaaagatac aagcccgtcg
    30181 gacgtgtttc aaattctgtt agatccattc gtaacacacg ttgaatcact attttgtagt
    30241 ctgtcccaaa aaaggagaga cgcaaatagt cgatcattgc tcgaagatct attccgcttt
    30301 tcatatacaa tcgaaagcgt tccttgattc gtttttcgaa atcctctggg attttctttt
    30361 ttccttgttc catcttcttt atataatcta ccgagcatcc caataactgt gcaaaacgtt
    30421 tttgagagag taattttttc cctccacctg aagcgtgaat agcactcaat ttttttcgat
    30481 aatttcgcaa ttcaataggt gtcatattct acctccttta taaaataaca aatttcgatt
    30541 ttcttaatct gctagaaatc ccgatataac aggtggtacc ccctaatttt tctaaaaagg
    30601 agtactcctt ctaaccttag ctaaagcctt gatataactg atttaaatac acttttttat
    30661 ttgtgttatg ttatttctgc cccccatatt atatatcggg gggctttaca caaagaggcc
    30721 gtgcgcaagc gcacgacctc tttgtgggca cacatgccaa gcatgtgctg ccacgactgg
    30781 tctcggtggc ttcgccgaca caagccgcgg cagcacatac tcggacaatg tgttctccca
    30841 tagtccctat gaaagccacc ccgatatcta aaccaatgaa tcttcttttt cttgtaattc
    30901 tttatactgt tcaggagcaa aacactgtaa aatcgctaaa cgtaactgta tgtttttctc
    30961 tttgcataac cgatatacct gacgaaaacg caatatatcc tcttttgtca aaacaatctg
    31021 atttctcgta acaaacaatg tctcgcgctc aattcgtcgg aaaacataag aaccttttgt
    31081 gtagtattct actttgttaa tccactcgta taatcttcga accgcaaaat caggtgaaat
    31141 ttcacccgca gctgaagaaa cacgatacaa aacttcaccc atacttcacc acttccttct
    31201 aaattataaa agtgtataac tttcctcatc taccccattt gttttcgtat ttccttttaa
    31261 cgattgcgct tgacgatcaa tttgttcttc gtaactagta aacgcctctt ctttcagtac
    31321 agaaaaatct tgcacaatca ttgtgtcaaa ttttttaaat tcctcaataa agtgatagtc
    31381 tttgtaaaca aatggcgcaa agaattctac aggcacatca aaaccaggaa aagcataccc
    31441 acgaccaggt tgatctttgt tataaaacgg cttattctta aaatcctctc caaaagtcat
    31501 taaatagcca atgggagata aacggccaac agaaatacgg aacgttaaac tatctcgaac
    31561 accacttgga aaatattccg catctggtcg ctgcatcgct aaaataacat acatgcctgc
    31621 ttgacgacct tttaatacta atggctgaat taatttatca actttgtttc tcgtttccat
    31681 atccaacgaa ccatagaaag ctgcccattc atcaaaaaag ataaaatgcg gcggtatccc
    31741 ataataagca taatttttcc ctggttcata cttaggctct ttcatcgttt tcatataggt
    31801 atatcgctga ttcatttctt gtaacgcatt tcgtaagcaa ataatcattt cttcattcgt
    31861 tttgtaaaac acatgtcctt tgaatacatc aatatcacct aatgccgcta aatctgccgc
    31921 tttcccatcg caaatatcta ctgtccctac atctaaacaa gctttgatca atgaatacaa
    31981 taaataggtt tttccgccac caatcgcacc agaaattaat agatttggcg attgatcata
    32041 tacccaatcc aatgttttca ttaaatgaat acgtccattt tctgctatac attgatcaat
    32101 aggaatccga ccagaatcgg aaagaaatac ataattgatt cgggcttttt ctcgttcttc
    32161 acgaattaaa tcacgcaaaa atacttcgga taataagcta cccattttta aaaatcgttc
    32221 gtggaaacgg ccaccatcta aaggaaaaga aaccactaat tcttgtttct tttgataaaa
    32281 ataaactttt ggtaatctca ttttttcctt cgtttgtttc tcaccaactt gcttctttgt
    32341 ataaacaaac cgattgtcaa ttaacattcg agcaagtaac tgacgccaat aaacagaagc
    32401 aaaatatcct tcctttagtc gcgaccaacg catcaaacct aaaattaatc cactaaccag
    32461 caacaaatac atcacaatac tgattccagg aataagatac atttgccaat tcgaatacgt
    32521 atttaaacga ggataaaata ctttccaact aaaccaactt aatagaatca aaaatggtaa
    32581 cagaaagaaa ccataataac aaaaccataa ataacgattg aaataacgaa ttcgtcgacc
    32641 acgatactta aaaaaatgag gttccaattg tcacattcct cctttctgtt tttacttctc
    32701 ctgtgctaaa aatttttgac aaaaagcaac taatactgga atatcacatt taataaaaaa
    32761 ccataatcga aaaagattta atcgattttt atatgggtgt gcacacatat tacatattcg
    32821 tactacacga atccaaacca cttcctgatg gtcttgtttc cactgatacg gtaatgaaaa
    32881 acgaacaaga tcacgtaaaa acatacactg cccaataacc gcacaaatat actcatttgt
    32941 ttgtataaaa atcgttggat tgtctccaaa atactcaatc aattgttgga tattttgaca
    33001 acaaaccata atctctcgaa gtgtttgatt ggttttgtcc agattcaaaa tctccccttc
    33061 cttctacctt aaatagaaag agtaggaaga cttcctccta ctctttaaaa aacttatttt
    33121 ttctcttttt ccttagaatc agcacttggt tgtttttgat ctaaaccttt ttcttgtgat
    33181 tgtttcggat tagaattatt tgttggagct tctactttct ctaatccttt cgcataaatc
    33241 actaaatctg aatattcacg attgccatct tgtgctggaa tatataccac atgatattct
    33301 ggatcaatta atttcacagg atcacgtcgt ttaaaaccag tcaaatctac atctgctgga
    33361 aatttaactc gtcgtgcaat ctttggttca tctggatttc caaaaactaa ttgtgctcgc
    33421 tgtgatcgaa tttctcccgt ataatcgcct gtttcattat caaatacacg atcggactct
    33481 tctaatgcgc caaagcgtac ggctcctata caagtttcat ctaatgcttc tgtaatatca
    33541 taattatttg gaaattttaa tcccatctta caaaacctcc tcaattttta caccagttaa
    33601 aaagacaccg acatcttgat agccagttgt tcgacgctct gtttgtccca tatcatttgt
    33661 ttcacgacta ttcactcttt ctttacgaaa aacaaaataa gcttcttcaa atgaaatacg
    33721 tacctctttt tctggtaatc gtaatctttt atcctcttca gctgtgagat aaacaaaaaa
    33781 agcaggctgt tcttctcgcg aacattctgc ttgtaattga acatatcgcc cagacacacc
    33841 attaatttcc tttggtggat taggttcccg tgaacccaat aaaaatacct gacctaaaaa
    33901 ctctttcttc atacgcaatg ctttttctgc catatcattt ttcctcctct taaaattcac
    33961 aatcaattct aaacgactct atattacaca atggaaagta atgtttaaca acaaatggct
    34021 catcactagg agacatatct actattaaca tcccgtctcg ttcatgcaca gaaatatcag
    34081 tacactcctc atacgtacat tcttttccac tcaaaaaaca aatatttata tttttctttt
    34141 ccatattctt ttttcctcca ttattttctt ttctgtaaaa accaagtaat aattcctttt
    34201 ccatcttcca acacaaactg atgatatatt tccctagcaa gaatccacac acatgctaaa
    34261 ataaagaaaa taataatact actaaagatg cactcatcct tgctgtcaaa cggaaaaaga
    34321 tatatcataa ttgcctcccc cataattaag aaaccaattg atacaaacaa aaactctacc
    34381 atcatacaaa agaatatttc ttccaactct tttacatcct ttctaacttt ttataaaaaa
    34441 ggagattatt tttataaaca cttttattca acaactattt tcaaatgaat tacacattat
    34501 catctcaagt atagtttcaa tcgtcactat tgtttggtcc atttctagct tttatttaaa
    34561 acatcgctat acaagaaaaa agaaaagcac tgaaacccta acaaaagaaa tgtttattcc
    34621 atttaaatct tcaattgaaa attatctatt tcaaaaaatt acaagaaaaa atattctaga
    34681 acgaaaacaa acaattcaac atctaatcca aacagttgaa aataaaaata tagactttta
    34741 tttgccttat gaacttattt attttgccaa agaaatacaa aaaataatta acacaaataa
    34801 acattcgaaa aaaatcctct tcaaagtaca aagaatgtat tttgaattct catactgcta
    34861 cctagcagaa ctaaataaag taagaaagca attaggagta gctaaacgtg atttcttcta
    34921 tagaaaaaaa gaaactgtat tatcacataa ttatattcta tctcttttgg atccttatat
    34981 tcttatttat tacactcagt atttcttggt gtatcctcat gatcatttac tactcaacac
    35041 aataatttat ttgcctttga taaaaaattc tttctaaaaa ctaaacaagc ggctagttgc
    35101 ctaaccgctt gttcgtcctc tttagtctct gactttatac aaatcataac caatcaatcc
    35161 tgccgcaagg acaaagatca taccaatcat gatccataat acattgtctt cagagcctgt
    35221 ttttggcaac ataggtacca ttgcagcttg tttcacttct tttacaggtt gtggttcgtt
    35281 tggttttact ggttgcggtg gttttggtgc ctccacaaat tgaaccgttt gatctttgtt
    35341 tgttagatcg acgttatgtt ttgcgacttc ttcaaacgtt tctttttcat cttctgtttt
    35401 ggcttggagc cattccgcaa aactcaatcc ttttcctgca aggttgcgac cgtcaacgat
    35461 gaattcaaac aagaattcca tcatttcttt atcagccata aagacttttt ccgcatgtgt
    35521 tccttcaaat ggggtgccgt ctggtgttaa gtagccttga acaatcagtt tgtaaatttg
    35581 accgattgct aacccattaa cttgaaccca ttcgacaacc ttttgatttg gtaaagctaa
    35641 gatctctttt ccaccatttg cattggtagc ttttgtcgta atggttggac tgacgatttt
    35701 gatggtttgg tctttgtcgg taatatctgc gtgagaagcc aataatacgc cttctctaaa
    35761 cagatcttca aaaactacga cttctttgct tcgcaacgca tgtgcgtcta ggataaagtc
    35821 tagattgact gtaccatcag ttgtttctgc cacaaacgtt aaggtacttg agacttcttt
    35881 tccatctact agcactggtt tttccgttac tttgtccatt agaacaccgt tgactgtgta
    35941 tgtttttcca acgatcaaat cgtggtattt cacagcgtct gtaatggtga ctttcgttaa
    36001 tggattaacc tctttcaagc cagtgggttt atgtgtagcc gttgtacgta cacttgggtt
    36061 cgttactcgt accgtttgac ctttgtcgtt gatgtcttta tggtttgcta gttcttcgtc
    36121 atttctaaaa agactttcaa acacgaccat ttcacgacca tttaaacctg tcaaatcaaa
    36181 ggtaaatggt acgatcaccg tttcattttc tgctttggca ataaagccaa cagcactttc
    36241 taccggttga ccatgaacaa gtaaggcttc accagttgct ttatccatta agattccttt
    36301 gaccaagtaa gcttttcctg gaaggatctc attaatttca acggtatcat ttaaggtgaa
    36361 cagccccgtt gggtctgcga tcgtcaaccc gtcttcaaat acagctgtgg tatgaaccgt
    36421 tggattgttt acccgaacac tttgattgtc atcattgata tccacatgta ccgcaacttc
    36481 aatgccatca cggaaaagtt tttcaaagac aacgattgtt tgacctttca gaacactagc
    36541 attaaccaca aattcaagat cttttgtgcc attggctttg tctgcaataa aggtcaagat
    36601 acttgtgatt tctttgcctt cttgtaaaat tggcgcattc gttgccttgt tcatcaatac
    36661 acctgaaata gtgtattctt tgccgacaaa caggttggta taagaaacac tatctttaat
    36721 gacgatagtt tctaatggat caaccacttt ttcaccatcg gctttatttg acgcttgtgt
    36781 ttctaatttt ggtggaatca aatagttacg tacagaaacc aataacgttt ccccatcatc
    36841 tggcgcattt tgtctgaatg taatagtgaa tgcttgtttg cctgtatttg gttggaaact
    36901 ttctaatggt acattttcgg taaagtaata gttattggca accagacctt ttactaaaat
    36961 ctcaccattt tgatcggtgg tatatttacc aattgcttga ccttttccgt tatatagcgt
    37021 aaacgtcaca ccggcaagtg gtgttttctt cttgttccat tcttcatact tgaacaattt
    37081 tacacttttc cgtgcttgac ggttcgcaaa atggatcact ttgatcggtt ctgtatcatt
    37141 ggtaatcgag aacactaatg ggttttgatt caaaacgtaa tttacgggtg ctttgatttc
    37201 ttccaaacga tagcgctctt ttccataagt aagtgtaccg ttagttagga aaaagccttt
    37261 ttcattggtt ttaaagatat ccgttgtttc tgtatcattt ggaatctcca ttgtgacata
    37321 acgattggct aaagtatcaa aaatcttgaa ttctgtattg gcaagtggaa tcacttttcc
    37381 tgtttcttga tccactttca ccactttaag acgttgttca attactttat cttctaaaac
    37441 ataatggaaa gtttgcccat tttcagaaat tgtgacttca agtggttcaa atagtttata
    37501 cccttctttt cctttggttt cagaaagaat gtaggtatca aagacaacag tatttttacc
    37561 aaaagtagcg taaccatcat tgtctgtcac aacggttttc accactttgc cagttgtttt
    37621 tgacgtcaaa gagatttcaa tgccagctaa ttttggtttg ttatctggat tggttgaatc
    37681 gactaaatct ttattagcaa ttttcactaa atcaatggtt cctttgatca cttgatcttt
    37741 tgcggtcgca ttgacagttt ttcctggttc aacaacaatt tcaattgttt catcagaaag
    37801 tgcatagcct ttcggcgctt tgatttcttt taaaacatat ttgccaggat caagatcttt
    37861 aatttctgcc tgtactttgc cgttcatatt tttcaaggta atttctttga tctttttccc
    37921 atctgcttga tacaagccat acaccgcatt ttctaaagaa gctgcgcctt gtgctttcac
    37981 accggtttct gcatcttctt taaagacacg aatgtttccc tgtttcaaaa tagtcaaatt
    38041 gacaacagag tcaccaggtt caaaaggatt caatatacca attgtttggg cacctggacg
    38101 acgatacgct aatggcgtac ccaatacttc aatctgattg aaatgaattt ttgccttttc
    38161 tggtgcttct tttgtgactg tgatccatgc ttcattccca tgaatagata cattgatccc
    38221 ttttggcttt tgaatgcctt ttacacgttg tagaaagtca ttgccacttt ttacttttaa
    38281 cgtttcgcca atttttatcg tatgtgtttg attatgaaaa gtagctctta catcaaaatt
    38341 attaagcaga cgttgaattt ctgcttttcg acgatcataa tcaacacgga tatttttgat
    38401 tgggattttt gtgcccaaag cttcccaaat cataaattgt gccgcaatgt attgttcatc
    38461 ggatttgtct ttatttgtga catatcctaa ataagagatc aagcttgttt ttttccgtac
    38521 atttgaattt ttcaaatagt tttccaaagc agtagctgta taaacttgac cttctgcggc
    38581 tgagacacca ggctcaatac aaaacgccac ttgtccatta atctcaaaac gaaccatata
    38641 atttaaagtg aagtttggat tgttcggact agaagtaaca ccaatatttt cgccccaatc
    38701 aattttccga ccacctaaaa cagctgtatt ggttgcacgg cgaacacgaa ccgaacgatt
    38761 ggttggtact gttactaaca gtgtaggtgt acctgttttt ggaatgtcct gctctttttt
    38821 cttttgatct tcaatactag ccgtagattc tttgtttagt ttcgttggtt gattttgact
    38881 agctgcggtt gaagagattg ttttttcaac gttttcctca ttttttcctt ctttgtcagc
    38941 agtagccgct ggttgttcca ctgtttcttc tattcgttgc ttttcttccg cttgtttctc
    39001 agaagactct ggcttcacag aaggcgttgc ttcggcagct ttttctcctt ctggagtgga
    39061 cgtttctgaa gcaggggttg taattgaggc agtttcttca actggttgtg aagtaacagg
    39121 actattccct gggtgttgtg tttccccaat cgtctgatcg agagtcgttt tggaattaac
    39181 cgttggcgct tctgtcacag gggcctgttc aacagtggct tcaccagctg ggaccccggc
    39241 ttctgctggt tggacttctg tcacttcaga agcgacttgg gcaatggctt ccaccgtagg
    39301 ttgtgtagcc gtcgtttctt ctgcatgtgc ttgagcagtt cccaccaaga aacagaattg
    39361 agataaggcc accaatgcga gtgctttcaa ccaattcatt ttcgtttttg catacacaag
    39421 aattcctcct tttcctgaga attttatata ataaaacaaa acaccgttac caaaagtgat
    39481 aacgacgtga actgtctctt ctatttttat ctggcgctct tatctgaaca catttcatca
    39541 atgattttac cctcccacta taattacaga acaaaaaaag aacctgcttc gtggaaatca
    39601 actgtccatt tcccaattgg aataccagct ttattggcaa cttcaccatc accaaatatc
    39661 atgccatacc aattactacc ttcatcctta atttctttcc aaccatatga catagcttca
    39721 tctaacgaat caaaaatcat gccactgttg ccaattgttg caggatctgg cttaagatct
    39781 tctggaatag aaatatcaat cacaccataa tgatccgatt ccccagtatt attgtcatta
    39841 ctagctactg gtttggttgt tctactgact tattttgata caacaagtac gcttattctt
    39901 cttttacttc tccgttttca atttcccatt caaaccactc cgcaaagtct tgcttaaaac
    39961 catctactcg atacctattt tgtaaatagg catcttctga cgtcgtagga tctaaatagg
    40021 taggtttatt ctctggacga gcatagacac ctacccatgt ttcgtaatct ccttcaaaat
    40081 aactatctac caaatagcct ttttttctaa gaatctcccg aacttgattt ttaattattg
    40141 atacttgttc aaaaccatca ctcattctat cacctcaaat aactctagat tctcataaat
    40201 attcccgaca atttcaatcc tatcaatgat ctctaacaaa tcgctactta tgcttcccca
    40261 ttcgtataag aatttccctt ccgcaaaata aattttccat aaacttcttc atgatcgtcc
    40321 caaccaatat cactctcgac aaattccacg ttgttcttat cttttagctc agtaaatgcc
    40381 ataagttcaa catgttttcc aacctcgaaa caatcacacc acccatcaac cgttacacgt
    40441 gtgccttcaa tacctaagaa actttgtcct cgtgtattaa acactaaaac tttccgcatt
    40501 ttttgctcat taattaatca cgcgcgaaat ctaggaatca caacttgttc gcttcttctt
    40561 tataaaataa aaaaactcca ataatcggaa attactatct tttcctcatt ccttttttaa
    40621 atcttcatac ttcttcttat ctttgtccta acctaataac acaaattttg aagaaaaact
    40681 cagtaaaacc tgattctttt tttatcttca caacaaccaa ctttttcttc agatcctttt
    40741 actagaactt gtatacaaaa attgttgaat gctgatacaa tttgcggtta cttgaaaaaa
    40801 cgatagatgt aaaaagataa atagaatcat ttttttattc tatatcagtc tatgattcat
    40861 tgcttatcaa tcacccaacc cattcgatgc cgttttttta agagaaattt aaaaaagacc
    40921 gtacgaatct cgcattgtcc gattactttt ctagaaaaga tccccaattc tgtataaata
    40981 accctatctt cttgttggtt tcattttctc atataagaat tcagtcaatc tacccactat
    41041 gaccattact acgtccaaca caaccgacat attaaccacg taagtattcc ctcacagatc
    41101 tccgaatttc catggtatgg attcccatcc tgacgctgca gaggacaaca tatttcatgt
    41161 ggctctgtac ccttttgatt tggaaagact acaaatcaat actcatctat aacttatcaa
    41221 gcgaactttc gctaggcttc tagtgattac taaattgttg gataacatac ctagcccatt
    41281 ttatctagct ggtattcata acagttattt cttgtattac ttcttccgct tgtgttgcca
    41341 ttgagcttgt caaaaagtta cttagaaaaa agctgccagt aaagcaactt tcaacaaacc
    41401 ctttttgttt cttatcatat caagaaacct ccttttataa atttttctat aataaaaaaa
    41461 cgtcgataac ttaataagta tcgacgtaaa ctatttttat atcccgtaaa tcaaaaattc
    41521 taaagaaaga tttcctatat aagcatattg gataattcga ttagtattgg gtatatctct
    41581 accattctca tacctatcta tggaccattt tgaaattgaa ggagaaaaaa gctttccaaa
    41641 ctcctccctt tctagataat aatctttcct aattttcctc atccttaatc ccatactaaa
    41701 agaatttatc ttgttaaaat cgctaactct ttcatctttt ggaagtatat tcttataatc
    41761 ttctccgtac ataaggtaag gaacagtgac cttaccaaga taggcaatat tcattagttt
    41821 ttcaatatct ggaatattaa tacctttttc ccatctactt ataacatttt tgcctgtata
    41881 gatggtaaag tttttaccaa atttttcaag cgtctcttcc cggttctttc ggacttctcg
    41941 tattcttttt cccataacaa ttttatcgtc ttttgataaa ctaaatatct cactatcacg
    42001 attactctcc ttcgaaattt ctttttcatt acttaataga aaaatatcga tttttttttg
    42061 catttctttt gacggatttc tctttctatt taacacataa ctgagtaata cttcactaat
    42121 tcctatatta tcagctaact ctttgttaag taacttattc atatctctgt atgcaattag
    42181 ttgaccgatg agaatctcaa tcttatcttc ctcatctttt attagagttt ctatattcaa
    42241 aatcttgctt agagtattat ctacgtcttt agggattttt cttgaccctt tttcatattt
    42301 aactaaagta ctttgtgaaa tacctgctaa atcagctaac tttttttgag atagtttttt
    42361 ctcttttctt agagatttaa gaacccttcc acttgaatta tcaaccatga aaaaagcacc
    42421 tcctatgaga tgctttcatc atatactgac agctaaaaat cttcaagaaa aaatattcca
    42481 attttgttaa ttttagtatc gccgtgataa ccaaatgaca gtttaaaatc ttttatacag
    42541 ataatcctca gtgttgcatc tactcaaaaa ggttgattta ataggttttt cgattgatta
    42601 taagttattt cacactatct tgctcatcca ttttcagaac ggccatgaag gcttcttgcg
    42661 gaacttcgac ggagccgatt tgtttcatcc gcttcttccc ttctttttgt ttctctaaga
    42721 gtttacgttt acgagaaaca tctccaccat aacatttagc caagacgttt ttacgcaagg
    42781 ctttgatgtc tgaacgggca acgatttttt gtccaatagc tgcttggatt ggcacctcaa
    42841 attgttggcg tgggattagt tttttcagtt tttcaacgat tgcttttcca cgttcatagg
    42901 caaagtctcg gtgaacgata aagcttaatg catcgacttt ttctccattc agcaagatgt
    42961 ccatcttcac taacttgctt ttttgataac cagacatttc ataatccaat gaggcatagc
    43021 ctttcgtgct tgatttcaat ttgtcgaaaa agtcaaagac aatttcagaa agcggaatat
    43081 tatagacgac atttactcgg taatcatcta aataatccat cgtaatgaat tctccccgtt
    43141 ttcgttgaga aagttccatt actgcaccga caaaatcatt tgggaccatg atctgtgctt
    43201 tgacgaatgg ttcttctaca tcctgaatcg ttacaggttc aggaaaatct gccgggttat
    43261 ctactgtagc agtcgtacca tccgttttat taacatggta aataacggat ggtgcagtcg
    43321 tgatcaattc tagattgaat tcccgttcca agcgttcttg gacgacatcc atatgaagaa
    43381 gtccgaggaa tccacagcgg aacccaaaac ctaatgcttg agaggtttct ggttcgaatt
    43441 gtaaagcagc atcattcaat tgcagttttt ctaaagcttc ccgcaaatcg ttgtaacgag
    43501 aagtatcaat tggataaaga ccacaataaa ccatcggatt catttttcgg taacctggta
    43561 aagcttcagc ggcaggattg tctgctaacg ttactgtatc ccctactcgt gtatcttgga
    43621 cagttttgat acttgctgtg atataaccga catcaccgac catcaaaaag tctctagcaa
    43681 ctgcttttgg cgagaagacc ccgacctctg taacatcaaa tgttttgcca ttactcatca
    43741 gtttgatttt gtctccgggt ttgaccatac cgtccgtgat ccggacattt agaacaacac
    43801 cgcggtaact atcataaata gagtcaaaga tcaaagcttt tagcggtgca tctaagtctc
    43861 cacttggtgc aggaacatat tccacgatct gctcgagaat atcttcaatc ccaatccctg
    43921 atttggcact ggctaataca gcttcactag catcgattcc gattacgtct tcgatttctt
    43981 gacggacacg ttcgggatct gctgcgggta ggtcgatttt attgatgact ggcaggatct
    44041 ccaaatcatt gtctaacgct aaataaacat tggccaatgt ttgtgcttcg attccttgtg
    44101 ctgcatcgac cactaaaacg gcaccctcac aggcagcaag gcttcgagag acttcatagg
    44161 tgaagtcgac gtgccctggg gtgtcaatca agtgaaagat atatgtttct ccatttttcg
    44221 ctgtgtaatt gagttctaca gcatttaatt taatcgtgat tccacgttca cgttccaaat
    44281 ccatcgagtc taacagctga tcttgcattt cgcgagacgt cacagtgtgc gtcatttcta
    44341 aaatacgatc ggccaatgta gatttcccat ggtcgatatg agcgatgatc gaaaaattac
    44401 gaatctgctc ttggcgttct ttcattttct ttatatccat agcgtctcct cttttcatat
    44461 aatcagcact ttccattata ccaacgaaaa gcagtaattt aaagagtttt taattagtca
    44521 gctatagaag ttttttttgt agaattttgc tatactgtta tcaagctaat aaatggagat
    44581 gaaaaaatgg atcaaaaaga ttttagagaa aatcttgaat taaaaccggt cactcaagaa
    44641 catatcgatc aattcaatga attgctttcc tatgtgttcc aagtgactga agcagacatc
    44701 gaggaaagcg ggtttgagaa taaacgagct tttatccgtt ccaaaaaacc gattttggaa
    44761 gtatcgaaag tgttcggatg gttccacgaa aataaactga tctctcaaat cgctatctat
    44821 ccttgtgaag tcaatattca cggtgcacgt tataaaatgg gtggtgtgac tggagttgga
    44881 acttatccag aatatgctaa ccatggattg atgcaagatc taattatcgt tgcattggat
    44941 aatatgcgca agaataagca atggatctct tatttgtatc cttacagtat cccctactat
    45001 cggcgtaaag gatgggaaat catgtctgat aaactttcct ttaaaatcag agatacacag
    45061 ctacctaaac aaatcccagt aagtggtatg gttgagcgat taccagttga tcatccagac
    45121 gtattttccg tttatgacaa atttgcccaa caaaaccatg gtgctttatt ccgcagtgat
    45181 tttcattggg aagagtattg gcgtttcgaa aatgaagatg agcgcacagc cgctgtctac
    45241 tacgatagca accatgaacc aagaggtgtt ctgttctact gggtagctga agaaatattt
    45301 cacgtaaaag aaatgttcta tcttgatcaa gaagctcgaa atggcttatg gaactttatt
    45361 tccgcacatt tttccatgat ctactgggta catggagata tttataaaaa tgagccttta
    45421 gcatttttga ttgaagatag tcagatcaaa gagcagatcg aaccatattt tatggctcgg
    45481 atcgttgatg taaaagaatt ccttcaacgg tttccgtttg ttggaacagc tgatgctttt
    45541 catttcatca ttgaagatcc tgtcgctcct tggaataatg gtgtcttcgc tttaacatgg
    45601 gatgaacagg gacaagtccg tgtcttaaat gaacctatag gaaaatccgt tcgactggat
    45661 atccaaacat tgacttgctt gatgatgaat tatcgccgtg cttcttattt ggcaagaatc
    45721 gaacggttag aaacagatga agaaacactg aagtcactag agcgtatcat tccaaacatg
    45781 gaagcttact ttagcgatta tttttgataa aaaggatgat gtttagatga aaatttattt
    45841 tgccgcacca atgtttgcta aaagtgattt gttatataac caacagttag ttaaagaaat
    45901 cagagagctc tcttctgagc tttcgatcta tcttcctcaa gaaaatgaag caatcaatga
    45961 caaaactgct tatgcagaca gtcgaatgat tgctcttgct gacacagaaa aagtgttggc
    46021 tagtgattta atgattgctt tactagatgg gctgacgatc gatgccgggg tagcatcgga
    46081 aatcggtgtg gcttatgcga aaggcatccc agtgatcggc ttatatactg atactcgaca
    46141 gcaaggcgga acccacccga aaaaaatcgc tgcactacaa gaaacagctg aaaatcaatt
    46201 tcactacctg aacttatata caataggttt gatcaaattg aacggaaaag tggtttcttc
    46261 agaaattgag ttgctttcag aagtaaaaag atttttagat ggagggactt tcagtgatta
    46321 aagaaatcaa aaaggtgcaa atagctttac ttgcttttgg tgtattcgtt gtctgctata
    46381 atttttatga atttatcaca caaaaatatt cgacttctca aggaatcaca tttatcgtgg
    46441 aatctttatt agggattgca ttgattttca tgccacaagt cattttgaaa gttttcaaac
    46501 ttaaaatacc agcagcaatc gttttgtttt actggttttt cttgttcatc tctgtctttt
    46561 taggcacagg gatgcatttg atcagtatca tctctttttg ggacaaaatc ttacatgcgg
    46621 tgagtccaat ggtcctgaca gctcttggct atggattgat tggttacttg atgaaagatg
    46681 ctgagatatc aaaaaccagt ccttggttgt tcctcttatt cggctttgcg tttgctggac
    46741 tttgcggcgt gttttgggag ttctgggaat tcttatgcga ccagttctta ggcatgaatc
    46801 ttcaacgttt tgctgcttct gatggcacac tgtttgtcgg acgagcagca ttgatggata
    46861 cgatgggcga cttgctgaca aatacgatag gtgctgcctt aatgggattg tttgcatggt
    46921 ctcaaagtaa aaaagatgag cgttactttg aaagttataa attagaaaaa gtgaaaaata
    46981 cctaataaaa gaggttgtga cagaagcggg cagcttcaag aaatttcggc ttatttttcg
    47041 aagaaactac ttctggaaca ctgtttattt gaaaaaagga ggtctgacac tagttgtgtc
    47101 agaccccttt tttcttttat agtctcaatg gaagattaga cgatttcttc tagctcttct
    47161 gttttgaaat gaagttgtcc atcaagtaaa gtaatcgtta cttttgattt aggcataaca
    47221 tgtcctgcaa cgatttcttt agctagtggt gtttctactt ccttagtgat aaatcgtttc
    47281 aatggtcttg caccatatgc tggttcataa gcattttcag caatccacgt tttggcttca
    47341 tcactgattg tcagcaggat ttcttgatgt tccagacgtt gtgccaattg cgccaccatt
    47401 ttgtcaacga ttcctttcac gttgtctagg ctcaatggtg taaataaaat cgtgtcgtcg
    47461 attcggttca agaattctgg tttgaagttt ccacgtaata gcgtgttgac ttgttcagcc
    47521 actgcttctg gaatcgttcc atcagcagtc acgccttcca gcagtaactg tgaaccgata
    47581 ttgctggtca tgatcagaac cgtatttttg aaatctacta ctcgcccttt tgaatcagtc
    47641 aagcgtccgt catctaggac ttgtaacaag atattgaaga catcgggatg cgctttttcg
    47701 atttcatcca acaagacgat tgtataagga tttcgtctga cagcttccgt taattgacca
    47761 ccttcttcgt aacctacata gcctggagga gctccgacta gacgagacac agcatgtttc
    47821 tccatatatt cactcatatc gatccgtacc atatgatctt ctgagtcaaa caagttctca
    47881 gctaacgctt tcgctaattc ggtttttccg acaccagttg gtcctaggaa aaggaaagaa
    47941 cctagaggac gatttgggtc ttgcaatcca gcccgtgaac gaattaccgc gtcactgacc
    48001 gcatcaactg cttcatcttg accaatcact cgtttatgaa gtgtttcatt caatttaatt
    48061 agtttttctc gttcaccttc tacaagtttc gttacgggga tacccgttaa tctgccaacg
    48121 acttgagcaa tctcattttc ggtaacggac tcttgaacca tcttaatctc gctgtctttt
    48181 gctttagctt ctaattcctt caattctttt tctaattgag gtatcgtacc atgacgcaat
    48241 acagcagcgc gttctaaatc atagttattt tctgcatctt ctaattcgtg ttttgcttta
    48301 tcgatttcag cacgttttgc tgaaacagaa ttgacttctt ctttttctgt ttcccactgc
    48361 atcttcatcg catttgcttc ttcacgaagt tcagctaatt cttcttgcaa atttttcaag
    48421 cgttttttac ttgcatcatc tgattctttt ttcagtgcag cttcttcgat ttccaactgc
    48481 atcaaacgtc tagtaacttg atctaattcc gttggcatag agttcatttc tacccgaatc
    48541 gttgcactgg cttcatcgat caaatcgatt gctttgtccg gtaagaaccg atcagtaata
    48601 taacggtcag ataaagtagc tgctgctact aatgcgttgt catggatgtt aacaccatgg
    48661 tggatctcaa aacgttcttt taatccacgc agaatactga tcgtatcttc cactgttggt
    48721 tctttgacta ataccttttg aaagcgacgt tccaacgctt tgtctttttc catatattga
    48781 cggtactcat ctaaagttgt ggcaccgatc aaatgtaatt caccgcgagc aagcattggt
    48841 ttcaacagat ttccggcatc catacttcct tctgtttttc ctgcccctac gatattgtgg
    48901 atttcatcga tgaacaagag gatacgtcca tcactttttt tgacttcttt caagactgct
    48961 tttagtcttt cttcaaattc accacggaat tttgctccag cgatcaatgc acccatatct
    49021 aatgaaaaaa tcgttttatc ttttaaattt tcaggcacat ctttgcgtac gatacgttga
    49081 gcaagccctt caacgattgc cgttttccct acaccgggtt ctcctatcag aacaggatta
    49141 ttttttgttt ttcgtgaaag aatacggatg acatcacgga tttcttcatc acgaccgatg
    49201 attggatcca tttttccgct tttgacttgc tgtactaaat caacgccgta tttttctaat
    49261 gctttgtatt gttcttcttg gttttgtgag gtcactcttt ctcctcctct catctcttcg
    49321 atgtttttac gcaattcttt ttcagataat ccgtttttat tcaaataaac agttaacgga
    49381 taatttttta atttcatcaa cgctaaaata acgacttccg ttgaaagaaa ctcgtcgccg
    49441 aagctttcac gtatttggtc tgcttcattc aataatcgaa agaaattctg gctgaggttt
    49501 tgtccatatt ggacgtttcc accagaaaca actggatact catccagtag acgatcaatt
    49561 tcatgttcaa aagattcgac atccaatccg gcatccgtat agaaatttcg accaaaatga
    49621 ttaggttgta aaaagatttt ccatacatgg gcaatgtcga tatcttgatg ttttcgagtg
    49681 accgcaatct gttgagcttc agcaatcgct tcttgaagcg tcgtagtcat tttctcaata
    49741 ttcatacagg tataccctcc taattaaagg taagatcact tatttctttg atctttacaa
    49801 aaactattat atcgctttgg tcaattttgg tcaaaatata cacatggttt tttgactttt
    49861 tttctcgact tatataaatc ttaaaaaaac aaaattgatt gtatgtatat aaaaaaagag
    49921 ccaaacaaac gtaaaattat cttatccata acgtttttct ttgatttgat aaaaagggta
    49981 gatcttataa aagacctacc cttgattttc tttattctct ttttttactt ctattatttc
    50041 ttctttgatc actcttcgcc gttcagcaat cacatacaca aatccataga gaaatggcaa
    50101 gataaaggaa ctgaaacgat acagtaaaag cgaagaaact gcgtcaactg ttccaacaac
    50161 tggtctgaat aataacaaat agacaaattc aaaggaacca ataccagcag gcgtaggaat
    50221 aacccctgaa agcactactg caaagctgat aaacgaaatg gtcagtagaa aatctatttt
    50281 aggatggttt tcaatcagaa tcaaataagg aagtacatac caaaatacaa gttttaacat
    50341 attccataga taaatccgca atagcgcagt cctgtcttgg ataatggttt ggaccgtttc
    50401 ccttaaagag tagatctgct gattgcatgt atccacccat ttccgcaaac gctcactttt
    50461 aaataactta ttcgataagc tgacaaaaaa tatttgaaca ttcaagctga cggacatcgc
    50521 caataaaaag gcaacaatca cgatcgtcaa aaggatacca gcgatgataa accagatcat
    50581 tgatggacca ttagaataaa aaagagagaa ttggatgacc aagccagcta atgcataagt
    50641 gatcactgcc agtttgtaca taatcatatg gagtgctgtc acccctgctc cctgggatag
    50701 cttcattcct tttttgttat aaaaataaat ctccgagatc agcgttcctg taccaaacga
    50761 aacgattcgg taaaacgcaa tatagctaga ggtcaagaac ccatctttcg ttgtaaaatt
    50821 cggcgcgaaa ggttcagcaa tttctttgat tgagcgccct tcagcgattt ggtaaactgt
    50881 ccctaatata acagccgctg ccaaaacaac aacactggta gacagcaatt cggcaaagat
    50941 atctgcaaat gattgattga ttaaataata aataatggca aaaatcacaa tcagcaaaag
    51001 cagattcaga atgattttag ttttcgttcc tttagacgac atctcctgct ccttaatgga
    51061 aaaaataaat gagaatcaaa tcaacaagta cacctgcagc gaatcctata gtaaacttct
    51121 ttttccgagt tttatgatgg aaaacttttc gagagatcaa tcctcccaaa ccaccgccta
    51181 acaggctgac aaatatcaaa ttattctcag gaacacgcca gccgctagtt ctagcctgat
    51241 gtttatcata ccccatcaga caaaataagt aaaaattcac aatgaaaagg taaaaccaca
    51301 aaagattgtg taacaataca tccattactc ttcttccaac tttctgttaa ctactatttc
    51361 taagcttttt cttctttctt tggtgaataa actgttaatc cttttgatac aacagataat
    51421 tcaactggaa gatcatctgt cgtgtctcca tccgttcgag tgcccacaga tttttcctgc
    51481 gcttggattt tcatgcgttt ggctgtgaaa taagtaatgc cggggatcgt atagaatttg
    51541 cctctcatga ttctaggcaa ataaaaaata aatcggaaaa tatctaagga aggtacgatc
    51601 gttacatgaa attttccatc atctagggtc gctgagtcgt caaaatttgt aaaaccgccc
    51661 acggagttag acatcgtgac tgtcaacagt tgggattttc ctttccaatg ctcctcgtct
    51721 gtttctaaat ccaaatgata ttttttcttc ttcagcaata acttaaaaaa cttcttgata
    51781 aagatccacg agccgtaacg ctgtttttct tcttgactga tccaaactgc tgtatctgct
    51841 aagattccga ttgtcagtgt agagataatg acttcatcat tgacttgacc atagtctatt
    51901 ttccgtacat tgccttccag gatcacgtca gcagcttctt cttttttgag gggaatctca
    51961 agaacacgtg caaggttgtt gacagttcca cctggaagta atccgacatg gtattgagat
    52021 aatgtttttt ggaacgcttg gacgatatga tgaatcgtgc cgtctccacc tataattact
    52081 aaagtatcag cttctatggc ttctgctttc ttgactaatt ccgcatcatc aatcgatggg
    52141 ccagtttcag ctagttctac atataattct ggctgctttt cttttacata atcttgaaac
    52201 cagcgtgcta atttctcacc ctcatctttc cctgaacttt tgttataaaa aactagcagc
    52261 ttttccattc tttacctcct atttactctt caaaaaagag ggcgggacaa ccaattccat
    52321 tgtcctgccc tttagcctta gacagatgac attccatcat tgggacgaac gccttgtcat
    52381 aagctgttct ttttcgattt taactctttg tgttcaattc tgcaattttt acaatcacgt
    52441 ctgttgcttt ttccattact tgtaaagaaa caaattcgaa tcgtccgtgc atattttctc
    52501 ctccggcaaa tagatttggc gtcggaatac ccatgtaaga gatttttgaa ccatctgttc
    52561 ctccacgaac tggttcgatc actggagaga taccaagctc gatcattgct tgtttcgcta
    52621 attccacgat gctcatatct ttttcaatga tttctttcat gttgtaatat tgatcataca
    52681 tatctacttt gattcgttct tgatcaaatc gctgattcaa ctcttcttgg atatgtgtga
    52741 tttgtgcttt gcgtgcttcg aatttttcac gatcatgatc gcgaatgata taactcatag
    52801 aagcttcttc aggattccca tccaatgcca tcaaatggaa gaaaccttcg tatccttccg
    52861 ttttttctgg aacttcatcg gctggaagct gattatgaaa atcgattgct aactgtagag
    52921 cattgatcat tgtatctttt gccgtccctg gatgtacatt tttcccttgg atcgtaatat
    52981 ttgcttgagc agcactaaac gtttcatact gcaactcacc taaaggacca ccatcgactg
    53041 tataagcaaa atctacatcg aattgctcaa catcgaattt atccgctccg acaccgattt
    53101 cttcatcagg accaaaagcc actttgatgg taccgtgagg gatagaagga ttattgatca
    53161 agatctccat tgcagtcatg atttccgcaa tccctgattt gtcatctgct cccagtaatg
    53221 tactgccatc tgttgtgatc aatgtgtggc cttcataatt tttcaaattt ggaaaatctt
    53281 ttgtattcaa tgtatagcgt tcttccgcat ctagtacgat cgtagactcg ccatcatagt
    53341 tttcaatgat ttgtggattg actcctactg cattaaaatc tgctgtatcc atgtgggaaa
    53401 taaatccaat ggaacgcact tcatgatcaa cattgcttgg taatgttccc ataacgaatc
    53461 cgttatcttc attatagaaa acatcagcta agcctaactc ttctaattct tttttcaatt
    53521 cttgcgcaaa agcaacttgt gtctgagtcg atggagtcgt tttgcttgtt gcatcggagc
    53581 gtgtttctgt tttgacatat cgtaaaaaac gtggcaaaag attttcgtac atagtattct
    53641 ctccttttaa ttaaattgaa atgggtttgt atttgtttca gaaacgaaaa agttaatatc
    53701 ccaattttct tcttgtttcc aagattcaaa tttctcgata aatcgttgct tgcataacga
    53761 ttcaatataa tgaccgggat caattgcaat caacccagcg ctttgcatat catgagccgt
    53821 atgataatag atatctcccg tgatatagac atctgctctt tgggcgattg cttgcggata
    53881 aaatttttca ccgcttccac cgcaaatcgc aatgcgcttc acagaggatt ttgcattttt
    53941 tggctggact attctcagtc catctagttg gaacgcttct tttacttgtt ctacaaatgc
    54001 ctctatagaa atttcttgcg gcaattcacc tactcgtcct aacccaaaca tttcgactgg
    54061 ttcatctata gcgaaaagat cataagcagg ttcctcataa ggatgagctg accgcatggc
    54121 ttgaatcact tgtttttcga tagtttccgg caaaataacc tcaacttttg cctcttgaac
    54181 ttgttctgtc ttccctactt tcccaatcgc tggttgtgca ccagcttccg gagtaaatcg
    54241 accgtgtcca atcgaggtaa aacttgtacc ggtataatca ccttgtgtac cagcaccagc
    54301 tgcagctaat acttcacgca ttttctgtgc atgatccaca ggtacataaa cggccagttt
    54361 tttataatga atctcatgag tctttactaa ataactctcc acttcaatac cgagaagttc
    54421 acaaaaccag tcattcagtc catcccaaat aatatccatg ttcgtgtgtg ctgcatagac
    54481 ggcaatatca tgtttcaaca aatctgcata cattttttct tgtggctgat cagtaaccag
    54541 ccgttttaca ggacgaaaga ttggaggatg tttagcaatc agcaaatcga tttttttctt
    54601 gattgcttct tcgaccactt ctggacgaac gtctaatgtc atcattactc gttggattgg
    54661 cttatccaat gttccgatat gcagtccgac tgggtctcct tcttcagcta gccactgagg
    54721 acaatagctt tcaaactttt ggatgaaagt gcgtccgctg attgtcatgg ctttaaaacc
    54781 tcctcaatca tttggatttc ctgctcgatt tgtttttgac gtgcctcttg attagctgct
    54841 tgtttgagct gttcacggat agcttttctt tgttgaagct ctcttgtcca ttttgatttg
    54901 aagatctcac ttttctcttc aagcagaaat ggcccgaaca tcagctccat ttcattgtaa
    54961 gtaactggtt tttgttcttt ttcggctaca atgatttcat atattttttt attttcttca
    55021 agtatttttt ctgattggat tttatactga ttttcttgca gccaagatcg taatgtacgc
    55081 tctccgatgt ttggctgaag gatcaaacgt tcttgtccgc ttaagcgttg attcaacttg
    55141 ccagcttcta ggatatctcg gatcagtgaa cctcccatac ccgcaatcgt gacagctgta
    55201 ataccatctt gtggctggat agcatctaga ccatttgcaa ggcgtacggt gatacggtct
    55261 tctaatccat cttttttgac ttgcttacgt gctgattcat aaggaccttg aacgacttca
    55321 ccagcaactg catattcgat ttttcctctt aatatcaatg caacgggtaa gtaagcgtga
    55381 tctgatccaa tgtctgctaa acgagcggat tcagggacaa agtcacccac tgcggctaag
    55441 cgctgagata aatctaaatg gttcatagct tcactccttc tagataatta tagcattttc
    55501 caaataaaat aaggagacta ggaa
//
LOCUS       DAFEIE010000011        52884 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFEIE010000011
VERSION     DAFEIE010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.011"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="LP345_000754"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="LP345_000754"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBL1759558.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="LP345_000755"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="LP345_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBL1759559.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="LP345_000756"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="LP345_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBL1759560.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="LP345_000757"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="LP345_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBL1759561.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="LP345_000758"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="LP345_000758"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBL1759562.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="LP345_000759"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="LP345_000759"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBL1759563.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQLKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="LP345_000760"
     CDS             complement(8053..8523)
                     /locus_tag="LP345_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBL1759564.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="LP345_000761"
     CDS             complement(8569..8994)
                     /locus_tag="LP345_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBL1759565.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="LP345_000762"
     CDS             complement(9061..9330)
                     /locus_tag="LP345_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBL1759566.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="LP345_000763"
     CDS             complement(9341..10936)
                     /locus_tag="LP345_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1759567.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="LP345_000764"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="LP345_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBL1759568.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="LP345_000765"
     CDS             complement(14489..15049)
                     /locus_tag="LP345_000765"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBL1759569.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="LP345_000766"
     CDS             15402..16376
                     /locus_tag="LP345_000766"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL1759570.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="LP345_000767"
     CDS             16546..17946
                     /locus_tag="LP345_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBL1759571.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="LP345_000768"
     CDS             complement(18024..18746)
                     /locus_tag="LP345_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1759572.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="LP345_000769"
     CDS             complement(18825..19331)
                     /locus_tag="LP345_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL1759573.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="LP345_000770"
     CDS             19454..21253
                     /locus_tag="LP345_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBL1759574.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="LP345_000771"
     CDS             complement(21321..22895)
                     /locus_tag="LP345_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL1759575.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERVEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="LP345_000772"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="LP345_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBL1759576.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="LP345_000773"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="LP345_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBL1759577.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="LP345_000774"
     CDS             complement(24672..25310)
                     /locus_tag="LP345_000774"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBL1759578.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="LP345_000775"
     CDS             complement(25311..25961)
                     /locus_tag="LP345_000775"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL1759579.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="LP345_000776"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="LP345_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBL1759580.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="LP345_000777"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="LP345_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBL1759581.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="LP345_000778"
     CDS             complement(29104..29844)
                     /locus_tag="LP345_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBL1759582.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="LP345_000779"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="LP345_000779"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBL1759583.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="LP345_000780"
     CDS             complement(31215..32153)
                     /locus_tag="LP345_000780"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBL1759584.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="LP345_000781"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="LP345_000781"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL1759585.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="LP345_000782"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="LP345_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBL1759586.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="LP345_000783"
     CDS             complement(35313..35618)
                     /locus_tag="LP345_000783"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL1759587.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="LP345_000784"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="LP345_000784"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBL1759588.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36724..37008)
                     /locus_tag="LP345_000785"
     CDS             complement(36724..37008)
                     /locus_tag="LP345_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759589.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37026..37916)
                     /locus_tag="LP345_000786"
     CDS             complement(37026..37916)
                     /locus_tag="LP345_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBL1759590.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37936..38154)
                     /locus_tag="LP345_000787"
     CDS             complement(37936..38154)
                     /locus_tag="LP345_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBL1759591.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38124..39824)
                     /locus_tag="LP345_000788"
     CDS             complement(38124..39824)
                     /locus_tag="LP345_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBL1759592.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40090..40863
                     /locus_tag="LP345_000789"
     CDS             40090..40863
                     /locus_tag="LP345_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759593.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(40944..41513)
                     /gene="thiT"
                     /locus_tag="LP345_000790"
     CDS             complement(40944..41513)
                     /gene="thiT"
                     /locus_tag="LP345_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBL1759594.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41579..41681)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41687..42658)
                     /locus_tag="LP345_000791"
     CDS             complement(41687..42658)
                     /locus_tag="LP345_000791"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL1759595.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42752..44125)
                     /gene="glmU"
                     /locus_tag="LP345_000792"
     CDS             complement(42752..44125)
                     /gene="glmU"
                     /locus_tag="LP345_000792"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBL1759596.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44628..45446)
                     /gene="purR"
                     /locus_tag="LP345_000793"
     CDS             complement(44628..45446)
                     /gene="purR"
                     /locus_tag="LP345_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBL1759597.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45613..46437)
                     /locus_tag="LP345_000794"
     CDS             complement(45613..46437)
                     /locus_tag="LP345_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL1759598.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46410..47090)
                     /locus_tag="LP345_000795"
     CDS             complement(46410..47090)
                     /locus_tag="LP345_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL1759599.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47113..48051)
                     /locus_tag="LP345_000796"
     CDS             complement(47113..48051)
                     /locus_tag="LP345_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBL1759600.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48296..49159)
                     /locus_tag="LP345_000797"
     CDS             complement(48296..49159)
                     /locus_tag="LP345_000797"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBL1759601.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(49301..51874)
                     /gene="mprF"
                     /locus_tag="LP345_000798"
     CDS             complement(49301..51874)
                     /gene="mprF"
                     /locus_tag="LP345_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL1759602.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52015..52821
                     /gene="proC"
                     /locus_tag="LP345_000799"
     CDS             52015..52821
                     /gene="proC"
                     /locus_tag="LP345_000799"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBL1759603.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
BASE COUNT        14662 a        11481 c         9505 g        17236 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc agttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaacacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcctg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatca cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gtaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ctagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttagtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc caattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gacatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatacc gagaaaatgg tttttgaaca tcacttattc
    36601 aaaataaaaa aagattgtga cacgaatttt gtcacaacct ttaaatgtat tcctagagca
    36661 aagaagctaa gcgaagaaat ccaattctga ttatttattg tatttctttg ttcagcatcc
    36721 ttgctaaaag cccatattgg acaaagtatt cactacaccc atgatctcat cttttcgaga
    36781 acgtgctttt tctgtcggat cttctacctc ttctgtgtca attcgaacaa taaatttccg
    36841 attcatcgtc acgtaagcac cgtcgttgat caaaataaac agttcgttct cattatagtc
    36901 tgcacaggca tctttccata cgtcaaagcc gtttttttca gaagggatat cccgtttaac
    36961 cacagttttt ccacttaatt cgtggaacgt tacgtcataa tatttcatta tctctacctc
    37021 tttcgtcatt caatattttg tacttgttct ctgatttttt ctaagatcgt cttagactgg
    37081 acgacttgat ttttaatttc gattgcattt gatttggaac cgatcgtgtt gatttcccga
    37141 ttcatttctt ggatcaggaa atctaattcc cgacctacag gacattgtgc ttcgataagt
    37201 tcatctagtt tttgtacatg gatcgccaga cgatccagtt cctcgtgaat atctccgcgt
    37261 tccaacaaga tggctagctc cgtcaacaac cgttgctcat cgactttcgc tccaagaaat
    37321 tcctccagct ttttttgata ccttatttga aattcctttt catagatttc tacaaaacta
    37381 tcgagttttt ttagtacttc tttgaattct tcagtattct ttttcaacac taaagctaaa
    37441 gcttgacctt ctttttctcg actcgcctca atagaatcaa gtgcgctttt caatgtatct
    37501 agagctaact gtgccaattc ttccatgctc tcttccggtt tttcttctac cgttacgaag
    37561 ttttcgtcca gcgcgaagcg ttccgccatc cgactaattg acacttgatt ttgactaccg
    37621 tatcgttgtt gaattccgtc tgtcaattga gtgataagtg aatcaatcaa ttcccagttg
    37681 atgacgatct gtttttcgtt tttgccaata taagctagat tcacaaatac ttcgattcga
    37741 ccgcggctta actgctgttt aataagctga cgaaaatcgt tttcaacaaa gttcaggatt
    37801 ttaggacttc gtatttgaac atctagaaaa cgctggttga cactttttat ttcaatatct
    37861 aactgatacg cttttgtttc gcggatggct ttgccaaaac cagtcatact tttcattcga
    37921 cagggtcctt cctcattaca tattttctat tgctttttgc agttgttcaa actcttcgtt
    37981 cgtcaatgtc aggcctttcc ccattttttc atggtctggc gcccaatctc gaagatcgaa
    38041 ttttggcggg cgaccattcc agctgactag gttcagttct ttacgccacc ccttgttgtt
    38101 ttctgacaat atagcgattt cttctacgat ttcatatgaa aattcttgtg ccatggttgt
    38161 tcctccttga gataatataa atataggatc agtaatgtgt caactggttg cttaagcaat
    38221 tcatgctgca aacgatcctt gcgttttcct tgtagcagat aatcaaaata aacagttttc
    38281 gtgcgctcat tttgtatttt ttgctggtat tttcgatacc ttcgccattc ttcagtactt
    38341 aattgaccaa tttgtgccaa taaatcatcc ggcatacttt ttatatcttg ttggcagatc
    38401 atttgaatca tcatgtctac ttgatagatt tcattgggca gtaaaaaatg tttttttgct
    38461 aaaagttcta gcatcgccaa tccgcatgtc tctggtacga ccctgttctt atataaatta
    38521 cgcagttttt gccaaaattt tatgcttttg aaaaaagata attctaactg aatttctttt
    38581 gttaagtaag acaaaaatcc tcgccagtat gttcttgcag gtttaacaga atgaaatgta
    38641 taccagttcc catagtaata gcctaatcgt tttttcattt ccagatagcc taattgtaaa
    38701 tttaattggt tcctttggct atcaaaaagc agaaagctgc ctagtgtcca caatgtttga
    38761 catttccaat ggataaaaat gtctggcata cgaatttttt tcgctgggcc tggcccttgc
    38821 acatctacga caaatgcctc tgttgctcct ttgttaatcg caatatcaat aggtattttg
    38881 ttgcgatacc caccgtctgc atatttattt tttccgatct ttcgataagc catagcggga
    38941 taaaatgaag cagaggcgag tatccaatct ggtatttctt ctgtttttgt ctgttggata
    39001 tcagtcacta cttccgctag ttctggcagt ttagtagaca ccgtatataa acgtattttg
    39061 ggattatgtt tgagtaagga caaatccaaa ttgtctttga ccatcttttc caatggagca
    39121 gaagaaaccc cgccttcaat tagtgctgtt ttcgtcattt ggcgtctttc tcgatagaag
    39181 cgttcacgaa ggtcttcaac tgcagccatt tctggtaacg caagcacttg tcttgtcgac
    39241 agctttttcc ataaattcac agcttttttc atatctcctt gtaaaatcaa tgcgccgttc
    39301 aacgcaccta ccgaggtacc tgtgataatc tcaaagttga tatcatgttc cttcagcgcc
    39361 tgccacacac caatctgata agcaccgtgt gctcctcctc cacctaaaac aagtgctgta
    39421 tgatagacca gctttttatt taattgtgtg gttccttgat agccgttttt atgaaaaata
    39481 cgcaaccatt cttctgatag aggagattga aataaaaaac aacagttttc tttaataaaa
    39541 aaacgagcgc aagcttccat ataccgaaaa aattttttcc attcaaaagt ttcaccttca
    39601 atcaacagat tattaaaaat aacatctcct ctacttttag caatagtaaa atagacggta
    39661 tattttttcg atactgcttt aaaagcacat tgcttttttg cagaacgcca aaaagcgtct
    39721 ctactttctt gatgactttg aaaaaatgga aggggttgtt ttgcttgctg gataggcgaa
    39781 tacagcgaca ttttctgtga aaagtaaact ttttttatct ccatcgcgct ctcctttttc
    39841 ttcaagtata ccagtacgtc ataaaaaggt catgagtctc gtattcgact ttgtagattc
    39901 cataagaaaa caattcataa aacatccttt aaataaaaaa tacaaaaatc acaaaaatta
    39961 attgaaaatg agagtgtttt caatgaaaac gtgattttgt aatggaattt taaaataaaa
    40021 gaaacaagct tttttaatgc aaatgttgta aaataaaaga gattaagagg aaataagagg
    40081 aggaacatga tgactgagtc agtttatgta catattgata ccacaagtaa tgctgtttta
    40141 acaaaagggc tgactgctac tgactttgca aacagtatcg tgcattttcc tcaaaacttg
    40201 ctcttgcttg atccatctgc ttctgctgga gaatatgaat cccatacagg gctgaaagta
    40261 atccgtggta cagaaaatat tcagcgtttc ttttcctctt ctcgtaacag gcgtggattc
    40321 gatgaattga agtggatcga ctttactgat ttaacgatgc tgaaagaatt gacaccttta
    40381 gaaatttcag aattattata ttttggtcat atgaaaacac atcttcattc gccgtttttt
    40441 tataaactac agaataattt tgtatacttc gatcttaatg atcagctgaa tcggatttat
    40501 tatcgctatt tagatgaatt ttataggatt tttgctagta aattaagttc gatcttgtca
    40561 gataagatca atgtaaaaaa atcttttttc aaaaaagaaa cacctgttga aaaaatcagt
    40621 gtggaattat tgaaagaaat gcgtaatttg atgcaggaag ggatcatttt ttcttttgat
    40681 caagttggtt tgatcgatgg taaatatcgt atcccaatct atgtgattga agattatatt
    40741 tggaaattaa aaggcacccg gtatcgagaa gaggaaatca tcgctacttt aatctactct
    40801 gtcaccgatc gacactggca attggtagaa gatgccgatc tttcttatct gccattgaag
    40861 tagatctatt tcttatcaaa aaataaaaag gaaacaagaa actaggacat gattctgtct
    40921 caagtttctt gcttcttttt tatttacagc tcctgtcgtt tatctggcac aaaaatcgaa
    40981 ggagtcgttt gttggatccc taataaaacg atgatcgtta caatagctgt actcaacccg
    41041 ctggcaccat tcattacgaa agaaaagagc caagaattca tcccccatag tgcatacgct
    41101 ccccagaaaa ccactcctgc aataaaatgc caaaaatatc tggaaagtgc gccaatcaat
    41161 gcaccaaaca cgatgctttt tctaatttgt ttcgtattat cgtctacata gcctttttgg
    41221 acatttgaag ccatgagccc tgctgcgcct gcaaaagtat aggcaatcgg gtactcaatc
    41281 aacacttgaa cgacacttaa ataataaact tgtcccaacg gaaaatgtag gatgccccaa
    41341 atgaaacctg ccagcatccc tgcctttgtc cctcttctta acgcaaaaag agtcaatgga
    41401 atctgcccta atgaaataga aaaactgctg ccgatctgga tcggaatcaa cgacaacacc
    41461 atcgctaacg ctgcaacaat cgttccttct acccaaactc tattttttcc cataaaaaaa
    41521 cttcctcctt tgaataaaaa agtcacaaag gaggaagcag ctttcgaaaa tagtcaaaca
    41581 gctgtttatt cacaattcct acgctcgcat aaccgataca ggtacgaagg gtttagaaat
    41641 agattcaatc tcagcccaat tggactcccc tttgtgagtt tatttattat ttattttttg
    41701 tttcaaacaa tggactaact ggtttgtttt catggatacg tttgattgca tctcccatta
    41761 gtccgccaac acttacttca tcgattttgt cgattttacg atcttctgga agatagatcg
    41821 agtctgtaac aactagacgc tcgatagctg aatcttctat tctttgtaaa gcagggccgg
    41881 ataatactgg atgtgtacat gaagcataca cactagttgc accagcttct ttcaaagcat
    41941 tggcagccaa tgtgatcgta cctgctgtat cgatcatatc atcgatcagt acacaagttt
    42001 tgcctttgac ttgtccaatg atattcatta cttctgcaac atttgctttt ggacggcgtt
    42061 tgtctatgat cgcaatcgga gatttcaaaa attccgctaa tttacgtgcc cgtgtgacac
    42121 caccatggtc tggtgaaaca acgacaacat catcgccttt gattcctttt tctaagaaat
    42181 aattggcaat aagtggcgca cccatcaaat gatcgactgg aatatcaaag aaaccttgga
    42241 tttggactgc atgaaggtcc aaagtcagca ttcttgttgc accagctttt tgaatcatgt
    42301 ttgctactaa tttcgctgtg attggttccc gtgcacgtgc tttacggtct tgacgcgcat
    42361 agccataata aggcatgact acgttgattg tttttgcact tgctcgtttc agtgcgtcaa
    42421 tcatgatcag caactccatc aagttatcat tgactgggct gctcgttgat tgaataacat
    42481 agacatgcga tccacgaata ctttcttcaa tgtttacttg aatttctcca tcactaaatt
    42541 gagtaacaga tgattttcct aactcgacgc cgactgctgc tgcaattttc tctgctaatg
    42601 ggcgattgga atttaacgca aaaattttta atcttgggtc aaagtaatgt tttgacatgg
    42661 ggacctccac tttctttttc acaactctag aattctacct aataaatagt agtcatattt
    42721 tttaaataaa tcaagtgatt ttgcaaaagt cttagtttag ataagggagt ttttttgcat
    42781 atccttcttt attgacttgt cttgctctcg caattgccag cgcatattct ggaatattgt
    42841 ctgtaattgt tgacccggca gcaatcgaac tgtttttagc tacctcgaca ggtccgatga
    42901 tattcgtgct agaaccaata aagctgtggt cgccgacagt cgtatgatgt ttgttctttc
    42961 catcatagtt gacgaagaca acaccacatc cgacattgat ttcttctccc agcgtagcat
    43021 caccaacata agtcaagtga ccgactttag ttcctttgcc gatttgagca tttttcactt
    43081 ccacaaagtt tccgatatgg acgttttcgc caatttcagc ttttggtcgt aaatgtgcat
    43141 aaggtcccac atctgcatgt ttcttgacat ggctgctttc aatgactgag ttttcaatga
    43201 cgacgtgatc ctcaatccta ctgtctacga tttttgaatg tgacccgatg acacaatcag
    43261 aaccaatgac tgtatttcct tggatttgta cacctgcttc gatcaatgtg tctggaccga
    43321 tttctacgcc tgcatcgatg tatgtcgttg ctgaatcgac aaagcttacg ccattgacca
    43381 tatgcatctg gttaattcgc tttctcatga tctcatttgc tttagctaac gcgatccgat
    43441 cattgactcc cattgattct tcaaaatcat ccgtttgata agcagcaact gtatggcctt
    43501 cttcttttaa gatttcgatg atatctgtta gatagtattc accttgagca ttgtttgttc
    43561 caactttgct taacgcatcg aacaaagctt cgttgtcaaa acagtaagtt cctgtattga
    43621 tttcttgtac aagagcttct tctggtgttg catctttttg ttccacgatt ttttctacga
    43681 tcccaatatg gtcacggatg attcgtccat atcctgttgg gttttctgct tgtgccgtca
    43741 agatcgttgc acttgcattt tttccttggt gatattcaaa aagattgttc agcgtttcag
    43801 tagtcaataa tggtgtatcg ccactgataa ctaacgttgt tccttttttt ccttccaaga
    43861 aagaagcagc ttgcaaaaca gcatgtcctg ttcccaattg ttctgcttgt aacgcatatt
    43921 tactgcgttc tcctagttgt gctttaactt gttctgctcc gtgtccaacg atcgtaatca
    43981 cttcatctgg tttcgtttca ctgacccgat taatgatatg ttctaccata ggtttaccag
    44041 aaacgggatg taaaacttta tataattttg acttcatgcg ggtacctttc cctgccgcca
    44101 aaataattgc ataacgtgcg tccaactgcg tcactcctaa atatagtttg ctgatttcag
    44161 tttatcccag tatacccatt ttttcaacaa aacaagtgat tttcttttat cccagcgttt
    44221 tctggataaa aaaatagata gaccataacg ggcctatcta tttggtaacc ggtgctctcc
    44281 tgccaactcc tcggtcacaa gtcacactac tcataaaaca tgaaaagctg ttttttgaaa
    44341 tcgtttcttg tgacttagag ttaaacggta ggcttacaac ctcttcatta aacgtttttc
    44401 aatcagctga ccttcggtat tagctcaata aacggcaaaa tatgaggagc aatttttccg
    44461 tttattgagc taatactcag gacaggacgc tgatttcaca acctctagat aaacggtgtt
    44521 caaaagccag tttctcggta ttaagccaaa tttatgaaaa aatgtggaaa gccattttca
    44581 caaaattttt cttactactc gaaactaagc ggctttttca caacctctta ttctgaaaaa
    44641 taatttcctg gcacaaccgt aatatttttc gtttgagtat ctacatcttt gacataaagc
    44701 agtgacgtat aatcatcgat ggcgcgatga ccgttgaatt ttgattcggc aaatacagtg
    44761 atgccaacaa gttctgattc gaattcttca atcaagctct tcattccgtt gactgttccg
    44821 ccgcctttca tgaaatcatc cactacaagg acacgtgaac cacgtttcaa acttctctta
    44881 gacagttcca tcttttcaat tctttcagaa gatccagaca catagttgac acttactgtt
    44941 gatccttctg ttatttttga gtcccggcgt acaataacga atggcgcatt cagataatag
    45001 gacacagctt gggcaatagg tacgcctttt gtggctacag tcattacagc atcgattttt
    45061 tcaccaaggt atttagaagc aatgattctt ccaacttgac gcagcagttc aggttctcct
    45121 aacaaatcag agagataaac atatcctcct ggaagcagac ggtcttgttc tgatagacgt
    45181 tctgctagag attcaatata ttttttcgcc tcttcatatg aaatttcagg gatgaacaat
    45241 acaccacctg cagcacccgg gattgtttcc aaggttccat accctcgttc tttaaatgtt
    45301 ttcttgatga ttcccaaatc ttcactgata gaagatttag cagattcata acgttcggca
    45361 aagcttgtta aggaaatcaa ttcatgcggg tgattcaata aatactgtgt catgtcaact
    45421 agacgttcac tgcgacgtac tttcacctat tccaactcct tttaagaaat tttatcgttt
    45481 tacattatat aagtttttct tcaaaaattc gagcatttta tgaaaaaata agaaaatagt
    45541 tcggtattta ttaaaataaa aagaagccta taaaaaattt ttcgttttta taaggcttct
    45601 tttctttata atttagttat tttttcttct gaaggcaacc aatattcgtt tgatgatatt
    45661 tacaatcagg aacaaagcaa taaagactaa tgtgattgtt gctcctggag gtgtatctag
    45721 ataaaacgag ctagttagtc ctgacagcat ccctagaaat cctacacaaa cactgatagc
    45781 aatcacgaca ttgaagcttt tgcctaatcg cataccgatt gctgcgggaa gaaccatgat
    45841 tgcggatatc aaaagtgcac cggcaatcgg gatcatcaca gcaatagcca caccagtaat
    45901 cacattgaac atcatcgaca tcaaatgaac gggtagccca tccacgtggg cggtatcttc
    45961 atcaaaagtc agaacataca tcggccgttt gaataaaaag aacaatatac cgatggcaac
    46021 gaataagatt cctaaaaaga tgacttgctc ccatgtaatg gtcacgatcg aaccaaacag
    46081 ataggattgg atacttgttg ctgaattccc tccgctcaaa ttcatcaata ctaacgctag
    46141 cgccaaacca ccagccatta aaatggcaat ggagatttct gaataggttc ggtagatcgt
    46201 tcgcagatac tccaatatca cagctgctaa tacaacgact agcatggtcg taagtgtagg
    46261 attaaggttc aaaaagaatc ctaacgctac ccctgctaaa gagacatgag aaagcgtatc
    46321 agccatcagc gattgtcttc tgatcactaa aaacacacct agcatcgggg cgattccggc
    46381 aatgaagata gcggcaagaa acgctcttct catgaattca tatgaaagca acgccattga
    46441 gaatcctcct ttctcaccag tcggatctgt ctgtccgcat actgtttgat atcttcatga
    46501 tcatgggtga tcattagaac tgatttccca tggacatgcg cactatgtcg gagaagacga
    46561 taaaattcat ttctggattc ttcatccata cctgttgttg gttcatcaag aacaaataag
    46621 tcagggtcag tagcaaaaat acgcgctaaa ctgattcgct gcttttgtcc gccagacaat
    46681 tcacctattc gccgatttcg catatcccac atccctacag cttctaaagc acgctgtaca
    46741 tgttgatgat ctttttcaga gagacgcttg aaccagcggc ctcttggata tcttcctgaa
    46801 cggactaatt cgatcaccgt actaggaaaa cctgcattga aagatgcaac ttgttgagga
    46861 atataaccga tacttaattt ttttccttct tgatttttct cagcaatctt tatcattcct
    46921 tttgaaggtt tcagtaatcc taacgatgct ttcaccaagg ttgacttggc tgctccattt
    46981 tctccagtta aaatgacaaa ttcacccgca tctacatgat aagagacatc ttctagtaca
    47041 ggttcatcat catagtaaaa ggtcaaatca gatatttcga tataacgcac cttacaacct
    47101 ccattctaaa acttaattga tactttcttt taaagctttc agattttttt ccatgacaga
    47161 aatataattt tcgcctgctt tgatttgttc attagtcaag ctttctaaag gattcaacac
    47221 ttctagcttc actcctgttt cattcgacaa tgtctcagct accttcgaag aggcattttc
    47281 ttcaaaataa atcactttga tgttgttttt cttcacaaat tcttttagct cagctaagcg
    47341 acttggtgtg ggttcctgat ctggtgaaac gcccgaaatc gctacttgtt ttaagtcgta
    47401 ttgattcgct aaataagcaa aagcagcatg ctgagtgaca aatgtgcggt ttgttgcatc
    47461 ttttagctca tcggagtatt tttgatccag tgcttcaagc tttttgatat aagcatcggc
    47521 attcttcgta aaagtttcct ttttatctgg atatttttcg cctaattctt cagcaatcgt
    47581 tctgacttct tttatagcta ataccggatc gagccaaaca tgtggatcgt attcatgtga
    47641 atgaccatgc ccttcttctg attcttcatg ttcgtctgct tcttgcgatt ctaaacggtc
    47701 gattccttta gctgcttcga tcatcaaggt ctgtttgcta tccactgaat cctttaacga
    47761 atccacaaaa aattccatgt ctgaactatt atacacgaaa acatctgcat cggaaatttc
    47821 tgctctttct tttgcacttg gttcgaaatc atgcggctcc gttccagcag ggatcaaaag
    47881 tttcacgttt ccttcatccc ctacgatctc ttttgtaaaa tcatacatcg gataaaaagt
    47941 cgtaacgatc gtcaaatcct cttttttgtc tgcttccttg ttcgtatttc cacatgctgc
    48001 aaacagtaaa gcacctatca ttaccgtagc tgtcaaaaga tattttttca tttatatgct
    48061 cctttcaatg aacaaatcgg aattttacga tttattaacg tgaactaatg tatcaaaata
    48121 aaaaaacaca gtcaatagaa atccatcaat ttctgattta agcatgtata ttcttgatta
    48181 aatcgtaaaa tggatgagtt gctgctcata tctagccatt tcactacaat aaaaaactga
    48241 agaataccat tttaggattc ctcagttttt catcacctat tttacttctt atattttatt
    48301 gcagggttcg tactaaataa acttcctcac aaaaaccttt taacccatta tatactctct
    48361 gcgctcttga ataatgttga cacaaggcaa aaacggttgg tccgcttcca ctcatcaatg
    48421 cagcatctgc tccgtacttg atcatacgct ctttgatttg atggatgact ggatgccgct
    48481 ttcccgttat atcttctaaa ctgtttccca tttttttgat catctgctga taatcttgct
    48541 ctcggatggc ttcagcaagt ccgtggatgt cttgatgttg gatggcttgc gtatctactt
    48601 ctctaaacac tgtacgtgta gagacactca ttcttggttt gaccaacaca acccagcact
    48661 gtggcataga aggtaatact tggatttctt cccctttgcc accgacaaat gccgtacttc
    48721 cgtagacaca gtaaggaaca tctgtaccga cttccaaacc gatttctgcc agttcttcta
    48781 acgaacagcc cagattccat aattggttga tccctcttag agcagctgca cagtctgtac
    48841 ttcctccgcc taatccagct gctactggaa tattcttctt aacaaagatc ttgacaccgg
    48901 ttttgatatt gtatttattt tttagcaata aagcagcttg ataaacattg ttccgttcat
    48961 ctaccggtaa aaatgcttta tttgtttcta caatgatttt gtcttctgtt atttcttcaa
    49021 aaaatagatg atctgccaag tctacgctcg acatcaccat ttccaactca tgatacccat
    49081 cttgccgtct atataataca tccagtccta aatttatctt ggctggcgct ttttcaatca
    49141 attccatcct ctcacccatt cgaaaagtct aagtcgcaag tattctatca tagggaaaaa
    49201 taaaagtata gcttatgtct gcctagtggt tgattttgtc atcgtttcaa cagctttcac
    49261 agaattttct cttcataatc caaacaagtt ctagtgattc ttataattct gtgagcactt
    49321 cttctgccaa actcggaaca tttccttttt cttttcctat cagactgagt agctgcatgg
    49381 tagcaaatcc gaaattactt cctttcctat aagcaaaata acgtccttcc caatgatcga
    49441 catattttaa tttcttttca taagcagact ggaaggaata gaaaaaatta ccataattat
    49501 atacgatatg catgactttt tcttgaaaga aagaaaaatc tgtttctcca acattagcta
    49561 atggagctaa gcctagattg gcttccgagt agcccatttt ctcgtataca ataaacagat
    49621 tggctaacag atagtcagct aattcctcag attctttagg taagacccgc aacaaatcat
    49681 atcccgcctg cttcttcgtc atcggctgag cggtgatgaa gccaacgact ttttgatctt
    49741 tacggacaat accgacaccg ctagataata catatgattt atcaaatcgt cccacagaga
    49801 agtatttttc tcgtgcacct tgaagccatt tttgtgaaac ttcatttaca gcttgatgta
    49861 attcttccgg cagttgatcg taccaagtaa aatggtatcc ttctttcatc aaacgttgat
    49921 attcaagttg ctgactcagc cgagacaagt cttctgttgc tagatcaaca atccctgctt
    49981 cacctacttt cgtgaagtga aaacccaatt catgaagcat cactacgtag ctttctgata
    50041 tcttataaaa cgcaagctga tagcctaaac aatctgcttg tttcataaac tgattcgttg
    50101 ctgcccgcat cattttagga ttgccaactg gatctcctaa aacaaagcat ttgtttcctt
    50161 tgatctgata accaaaaacg acttgatctt ggtcgtcttc ttggtaataa aaataactgt
    50221 aacctgacaa gcgaagctga tggcttgtag ctgtgcctcc gtatgtttcc aataaacggt
    50281 caaaacggtc tttttcgtac tcactgccaa gcttcgtagt atcttcagct aaatattgat
    50341 aaagcgccac taaagctagc aatgagatgc ccaaaccaat aagccctgag aaccacacat
    50401 catctgaagg aaacaaaata aaatgatttc ctgttattcg accgactaaa aagcgtccgc
    50461 tgtgatagcc tgcaattgcg taaacgataa acaaaaagcc gaacaagcta gcatcaaaga
    50521 ttatagctcc ccaagaataa acgaattttg ttcgataaaa ttcttttctg gataaccaca
    50581 cagctaacag aatcaagaca tataccaata tcaactgcca agataacgta cgtgtgattg
    50641 tatttaaaat accaaaagat agtaaagcaa tcgtaggcag aaatgccttt ttgactttta
    50701 ctgaaagtgc tctagcaagg ccgagtaata aaaagccaac caatagattc actgtctgat
    50761 ctaaaaaatt gaatgagaac ggcaataata cttgaaatag ccgactgatt gcagacagat
    50821 tagtgattgt tgatagaagt accatcatga tccccgcaaa atagacagca cttacgagca
    50881 cgatatgcgc aaccttttgg aaaaacagtc gcggaatgtt atctaaaaat cgattgattt
    50941 tgactcctgt atgtgtgatg aacaatagaa gtcccgtcat aaaaggtaga acataataaa
    51001 acaaccgata atataatagc caaactactg ctacatcttg ccgaacagac aattgactca
    51061 ttcctaagat catcaaaacg tcaaaagtcc ccattccacc tgggaccatc gtcagcattc
    51121 ctatcaatgt agcaatcatg aacataggat agatcgaaag catcgaaata tctattctca
    51181 tcaacttgcc gatgatcaaa aataccgcaa gggctcccgt ccattgtcca aaggatgcca
    51241 gtagcagacc aagcaagcct tttggataaa actcgaagaa caatgtcttt ctctttagat
    51301 aagcaaaaaa gaaaatgact ggtgctaaaa aactaccgcc gaaaagccag atccaatagc
    51361 ttcgaaaaat actttctgac tgaataaaaa agacatcaat aaatgtaaga aacgaccata
    51421 cagacaaacc agtcagcata aatagtgcga cttttgatac agtggctaaa accatttttc
    51481 tatttgtctg ctttccataa aaactagccc gcagacttgc tcctaccaca ccaccaaaac
    51541 cggcgagatt gttgatcgtg tttgttaccc acgcagcaag aagaaactct tttctttcca
    51601 tttttggttt tccttgtttt tctaagactc tgatcgtcac ccaatcatac aacaacatcg
    51661 gagtgacacc cagcagtcca gccagaatca tgagcaggat cgtcatgcgg ctttgttgtc
    51721 ccatcctttg ccaaatatct tgccaactca tgccattagc aatatttgcg acttgatttg
    51781 ccacaaagac taacacggag ccgaaaaaaa tcagttttaa aatcagacta tgttccttta
    51841 tccattgcag catcaagtat cgtttatttt tcacattttc ccattcctaa cttgtatact
    51901 tttgtgtcat accccaatgt tatcttattt attttaattt ttccacttta gacctgttct
    51961 ttgcttgcga tgatagaaaa agaaagatat cctaatgcta aaggagagga taacatgaaa
    52021 gtaggattta tcggcacagg gaatatggca caagctatta ttgatggttt attaaaaaaa
    52081 ggaacagtct cgaaagaaga ggtgttcgtt tccagtggac attttgaaaa tgcacaaaaa
    52141 tttgctgctg aaactggcgt ccatgcatgc aaaagtaatc aggaagttgc atcacaatca
    52201 gatatcgttc ttttagccgt gaaaccaaaa atcattgaaa aagtattgga agaactaaga
    52261 gaatatagcc agaaagtctt attcatttct attgcttcag gaaaatcatt aacagattta
    52321 gaaacagcgc ttgaagatcc tcaggcctcc atcgtacgtg tgatgccgaa tgtcaatgtc
    52381 agcgtaggag caggcgtttc tgcgatttgc aaaaatgaag ctgccacgga ggaacagctt
    52441 cagcaagcta cgatgatttt tgaagcaatc ggcagcgtct atcctttagc agaatcagat
    52501 ttcagtacat tcattggcct tgctggcagc tcacccgcat tcgtttacat gctgatcgat
    52561 gcgatgggac ggactggtgt actgaatggt ttgtccaaac agacagccac tgagattgct
    52621 gcaaaagcaa ttatgggttc ttgtcaaaaa ttcctttcaa gtgataaaaa tccatgggaa
    52681 cttgtagacc aagtttcttc tcctggcggt acaactgttg caggtgtagt tgccttagaa
    52741 gaagcaggat tcatcccagc aatcatcaaa ggaatcaata cgacgatcga gaaagatctt
    52801 gagatgttga ataaaaaata atgatagcaa tgttttttcg taccttacaa aaaaagaaga
    52861 gctgtggctt ttgccgcggc tctt
//
LOCUS       DAFEIE010000012        49474 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFEIE010000012
VERSION     DAFEIE010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.012"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            131..505
                     /locus_tag="LP345_000800"
     CDS             131..505
                     /locus_tag="LP345_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1759604.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="LP345_000801"
     CDS             complement(619..1248)
                     /locus_tag="LP345_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1759605.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="LP345_000802"
     tRNA            complement(1382..1454)
                     /locus_tag="LP345_000802"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="LP345_000803"
     tRNA            1668..1741
                     /locus_tag="LP345_000803"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="LP345_000804"
     CDS             complement(1879..2043)
                     /locus_tag="LP345_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759606.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="LP345_000805"
     CDS             2338..3666
                     /locus_tag="LP345_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBL1759607.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="LP345_000806"
     CDS             3868..4701
                     /locus_tag="LP345_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBL1759608.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="LP345_000807"
     CDS             4717..5454
                     /locus_tag="LP345_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBL1759609.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="LP345_000808"
     CDS             complement(5609..6577)
                     /locus_tag="LP345_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBL1759610.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="LP345_000809"
     CDS             6809..7642
                     /locus_tag="LP345_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBL1759611.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="LP345_000810"
     CDS             7676..8515
                     /locus_tag="LP345_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1759612.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="LP345_000811"
     CDS             8541..9101
                     /locus_tag="LP345_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1759613.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="LP345_000812"
     CDS             9300..11021
                     /locus_tag="LP345_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBL1759614.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="LP345_000813"
     CDS             11186..12328
                     /locus_tag="LP345_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL1759615.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="LP345_000814"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="LP345_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBL1759616.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="LP345_000815"
     CDS             14128..14775
                     /locus_tag="LP345_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL1759617.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="LP345_000816"
     CDS             15168..17813
                     /locus_tag="LP345_000816"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBL1759618.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="LP345_000817"
     CDS             18123..19436
                     /locus_tag="LP345_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBL1759619.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="LP345_000818"
     CDS             19426..20079
                     /locus_tag="LP345_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1759620.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20805
                     /gene="radC"
                     /locus_tag="LP345_000819"
     CDS             20134..20805
                     /gene="radC"
                     /locus_tag="LP345_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL1759621.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAYPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(20700..22052)
                     /locus_tag="LP345_000820"
     CDS             complement(20700..22052)
                     /locus_tag="LP345_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1759622.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELRNNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDCQGSVA
                     GQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEATKQKF
                     EQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLAEYKKDREALMKELNE
                     IEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNITVNFLI
                     "
     gene            complement(22118..23407)
                     /locus_tag="LP345_000821"
     CDS             complement(22118..23407)
                     /locus_tag="LP345_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBL1759623.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(23494..24198)
                     /locus_tag="LP345_000822"
     CDS             complement(23494..24198)
                     /locus_tag="LP345_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HBL1759624.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            24398..24664
                     /locus_tag="LP345_000823"
     CDS             24398..24664
                     /locus_tag="LP345_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1759625.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            24677..24835
                     /locus_tag="LP345_000824"
     CDS             24677..24835
                     /locus_tag="LP345_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759626.1"
                     /translation="MEEKNIKVPTLEEYTKIVVETDEQNPKTIAVITANDIESCEGFR
                     VRMTPRYD"
     gene            complement(24832..25062)
                     /locus_tag="LP345_000825"
     CDS             complement(24832..25062)
                     /locus_tag="LP345_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL1759627.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            25134..25289
                     /locus_tag="LP345_000826"
     CDS             25134..25289
                     /locus_tag="LP345_000826"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759628.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            25446..25601
                     /locus_tag="LP345_000827"
     CDS             25446..25601
                     /locus_tag="LP345_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759629.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGEKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(25598..25822)
                     /locus_tag="LP345_000828"
     CDS             complement(25598..25822)
                     /locus_tag="LP345_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL1759630.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            26089..26424
                     /locus_tag="LP345_000829"
     CDS             26089..26424
                     /locus_tag="LP345_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759631.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            26657..27598
                     /locus_tag="LP345_000830"
     CDS             26657..27598
                     /locus_tag="LP345_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBL1759632.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESSIRQVDNEIISELGKREASIGITQRNIISWKLVR
                     TRRMNTKKLAEKYPDVANDEEIYNVTESRRLTEKEIK"
     gene            27600..28490
                     /locus_tag="LP345_000831"
     CDS             27600..28490
                     /locus_tag="LP345_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBL1759633.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            28533..29333
                     /locus_tag="LP345_000832"
     CDS             28533..29333
                     /locus_tag="LP345_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL1759634.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            29348..30199
                     /locus_tag="LP345_000833"
     CDS             29348..30199
                     /locus_tag="LP345_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1759635.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGSIA"
     gene            30196..30555
                     /locus_tag="LP345_000834"
     CDS             30196..30555
                     /locus_tag="LP345_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBL1759636.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            30570..30731
                     /locus_tag="LP345_000835"
     CDS             30570..30731
                     /locus_tag="LP345_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL1759637.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            30728..31054
                     /locus_tag="LP345_000836"
     CDS             30728..31054
                     /locus_tag="LP345_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759638.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            31051..31866
                     /locus_tag="LP345_000837"
     CDS             31051..31866
                     /locus_tag="LP345_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBL1759639.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            32005..32316
                     /locus_tag="LP345_000838"
     CDS             32005..32316
                     /locus_tag="LP345_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBL1759640.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDV
                     K"
     gene            32313..32543
                     /locus_tag="LP345_000839"
     CDS             32313..32543
                     /locus_tag="LP345_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759641.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNIELPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDDTFRLGS"
     gene            32550..32753
                     /locus_tag="LP345_000840"
     CDS             32550..32753
                     /locus_tag="LP345_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBL1759642.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASDAIRKFGISILNDDRKWEEMR"
     gene            32750..33049
                     /locus_tag="LP345_000841"
     CDS             32750..33049
                     /locus_tag="LP345_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759643.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVINNEV"
     gene            33039..33203
                     /locus_tag="LP345_000842"
     CDS             33039..33203
                     /locus_tag="LP345_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759644.1"
                     /translation="MKFKIFEEDTRYKLEKELNDFAKNNEIQHISLATSKRGYANYYA
                     AVVSYVSREV"
     gene            33292..33705
                     /locus_tag="LP345_000843"
     CDS             33292..33705
                     /locus_tag="LP345_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBL1759645.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILVALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            33718..34104
                     /locus_tag="LP345_000844"
     CDS             33718..34104
                     /locus_tag="LP345_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759646.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            34655..34879
                     /locus_tag="LP345_000845"
     CDS             34655..34879
                     /locus_tag="LP345_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759647.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMIREAT
                     PVEIDYCKLVYCGCGRWKEDHVQKNISKYI"
     gene            34897..35325
                     /locus_tag="LP345_000846"
     CDS             34897..35325
                     /locus_tag="LP345_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759648.1"
                     /translation="MEKSDTKANRYKPTAAEKKLLEVLINPDNLGKPVQELCSLAKIG
                     RTKYYDAMSKDGFVDLVNETTMDLIKGKASDVLNATYKYALTEKGHQDRKMILTIAGI
                     YADKQELKHSGGVDIRKQYEKMSDEELEELVKRYEKINDS"
     gene            35303..36721
                     /gene="terL"
                     /locus_tag="LP345_000847"
     CDS             35303..36721
                     /gene="terL"
                     /locus_tag="LP345_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBL1759649.1"
                     /translation="MKKSTTLNRVEYAVVQRELAIRKARKSFWLFCQLLYPEFYKDDR
                     LYLKDLCHTLQDFYEDKIDKKILVINMPPRHGKTFTARLFVLWMFGQNPKTKIITGSY
                     NQILSSLFAQQTRDGIMVENENVKAEYFKDIFPEVQIKYGDAAKGFWSLDGSEEKNYL
                     ATSPGGTSTGIGANYVIVDDIIKTAEEAYNERVLDSHWEWYNNTLAQRMERPRKQILI
                     MTRWSSNDLAGKMLTRRKNNVHQICYKAVQEDGSMLCNEIMTHDEYLDVVQEMNVDIA
                     EANYQQEPIDQKGRLYQKFLTYDTLPDNIIKIWNYTDTADKGADYFASPVFAETSDHD
                     AYIIDVMYTKEPMETTEIAHANMIIRNRVNKVRIEGNNGGRGFRRNSERITKERGYRG
                     AVFEDFHQSDNKLSRILANSAWVENHVYYPDDWATRWPDFYEAMVSYQREGKNAHDDA
                     PDAVTGIAETIIEADDFEFIAY"
     gene            36733..38268
                     /locus_tag="LP345_000848"
     CDS             36733..38268
                     /locus_tag="LP345_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1759650.1"
                     /translation="MFYSGITLKKYKRLRTKYSTQIEEGLFDPNAFMEDMKPFFDDRE
                     RKYLAYTSEKNEIDSREKPKTKIIKVNNKIHAGMYSVVVDQAVNHFTGIPIKWDYDVS
                     EQKRTFIQRMRDKLLGNDISAPSTPEEFETLTRQLSTMRFGMLDPDTATFQGATGLAF
                     RLLEPVETNDGWELRASNIEPWKAEKYENGAVYIKEKYDPYQKKFYEEMKVVTPKSIF
                     TYARYTDYPGTVQGAFKTLGNVPNPLGVINLTEFKNNTNRYCDFEVAEEISDAIDRVL
                     SDQQNEIEQFKLAYMLITGADLSEDKAKKMMEQLGIINLKDPNAKAGYVTKDLQKDFN
                     EYHFDLLKKQFYTVCKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAEVMAAYLDFAEKVTIDPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMIDVESRQSYPDGEYGGGIVESNRNEVLDQTSRTGRFSKTQNGKSNAK
                     ETK"
     gene            38348..39226
                     /locus_tag="LP345_000849"
     CDS             38348..39226
                     /locus_tag="LP345_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBL1759651.1"
                     /translation="MMEFYSTSDQKKYREYVEKNYKSLKMYDAKYKEFIEEYFPSFDY
                     AKVNRLLQMRSDIFRILAESAIDADVNKYFSDRLEDILQRSYVSNANVFAQILNVDLP
                     NYLSKEELERYLNYPWSGKTFSRRLWGNISSLEQKLSNAITTSVASGEGVLVALRTMR
                     EDPEICDMFKREESKYNKAIENLVRTEYAKFAQDGIEKSYIETGVDEYNVLTAKDEKV
                     CSICGGKAKNNPYKLSEAIIGENRAPFHGRCRCTDVPNMPKLGKDIDEEYERLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            39228..39545
                     /locus_tag="LP345_000850"
     CDS             39228..39545
                     /locus_tag="LP345_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759652.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYENMGCIVVRTDYKEGK
                     SSN"
     gene            39672..40295
                     /locus_tag="LP345_000851"
     CDS             39672..40295
                     /locus_tag="LP345_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBL1759653.1"
                     /translation="MIMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            40310..41200
                     /locus_tag="LP345_000852"
     CDS             40310..41200
                     /locus_tag="LP345_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBL1759654.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            41223..41438
                     /locus_tag="LP345_000853"
     CDS             41223..41438
                     /locus_tag="LP345_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759655.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            41450..41791
                     /locus_tag="LP345_000854"
     CDS             41450..41791
                     /locus_tag="LP345_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759656.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            41791..42162
                     /locus_tag="LP345_000855"
     CDS             41791..42162
                     /locus_tag="LP345_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759657.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            42155..42550
                     /locus_tag="LP345_000856"
     CDS             42155..42550
                     /locus_tag="LP345_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL1759658.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            42552..42929
                     /locus_tag="LP345_000857"
     CDS             42552..42929
                     /locus_tag="LP345_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759659.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            42930..43538
                     /locus_tag="LP345_000858"
     CDS             42930..43538
                     /locus_tag="LP345_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1759660.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            43538..43879
                     /locus_tag="LP345_000859"
     CDS             43538..43879
                     /locus_tag="LP345_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759661.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            44121..46910
                     /locus_tag="LP345_000860"
     CDS             44121..46910
                     /locus_tag="LP345_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBL1759662.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEEFRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNEIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            46900..47640
                     /locus_tag="LP345_000861"
     CDS             46900..47640
                     /locus_tag="LP345_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1759663.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYRNVTRKIECYYKAPSIDVVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            47637..>49474
                     /locus_tag="LP345_000862"
     CDS             47637..>49474
                     /locus_tag="LP345_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1759664.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLAEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRLIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     SLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFTSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT        17093 a         7760 c        10176 g        14445 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaattattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctta tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tccggaatat ataagttagt acacataaat
    20701 tatataagga aatttactgt tatattgcca tctggaaata ctattatgtt atcgataatt
    20761 gaacgccata atgcattttt ttcttcttcc gaagattctt tataaatttc atcgaattct
    20821 tttgatagaa taaattcgac attttttata tctattttag ctggctctac ttcaatttca
    20881 tttaattctt tcattaaagc ttctcgatct tttttgtatt ccgctaagtc tataacttca
    20941 ttcaagtagg ctttcttcaa tctatctaat ttattctcaa tatttttctt actatttttc
    21001 tttttaataa tctttggttg tttttttgaa tagtttattt gtatttgttc aaatttttgt
    21061 ttagtagctt caaaaatata acgttctaaa tttttttcgt aaaaagcgcg cttatttgtg
    21121 caacgtaatt tattatttct tcgttttaca catctataac aagtcctttc gtatatagat
    21181 tctgtaccgt cttttttctt atatcttgct ttaatagttt gaccagctac tgatccctga
    21241 cagtcagaac attttaataa acctttaaaa atgtaatcac gttttgcatt tgtttttaaa
    21301 tttttaggta aggctttttg aacagcataa aaaagttttt tatcaataat aggaggacag
    21361 taatttttat tatttcttaa ttcaccaatg tattttttgt tcgtcaacat atttttaaca
    21421 ctttgataat ctctaacgat tccatactga gagcctaaat aataaacagt ttttcttaaa
    21481 ctaccactag aaagaaagta gttgaatata tctatcacga taggagcatc atcatttatt
    21541 actaatttct tattttctat agagtagcct aacggagttt tcccgcttac tacttcacct
    21601 tgtgcaattt tatttgccat aacagctttg atgcgttctg aatcaatttg ggcttccaat
    21661 tcagcaaaac tcattacttg tgcaatgaaa gttctgccat acgctgtagt tgtatcataa
    21721 tattgttgag aaacagcatt ccaagaaaca ttgtgttttt ctaaaatttc ttgagtgttt
    21781 aaataatgtc gtagatttct aaaccatcta tctaattttg taaataaaat tagatctatt
    21841 ttattttctt ttacatcttg taatagtttt tgaaattcat cacgatttat tttttgacca
    21901 gaaataccac cgtctacata ttcattaact actttcaaat ccttgtgttg ttcgatatat
    21961 tcatagaggg tttctttttg ttctctaaga ctatctccat gtttggcttg ttgttcagtt
    22021 gatactctca tatataatgc tactcgtttc atgttatctc ctttcgaatg tatgttctta
    22081 tcgttgtaaa agaaaagccc gaaggctaat ctttttacta cacatctgtt aattctaatg
    22141 atcttctgta ttgttcagct tgagctagtt tagtaaaaga tacagttccg ttataatttt
    22201 ctaaaacaac tttttcaatt tcatcaagag atactttaaa gaattctttt cgttgattaa
    22261 ctttattgac ttcgtttttt ctaaaatgcg aatgtagttg attttctaat gttggtgcat
    22321 cttctgaaaa tatcattgca tgaacatcaa attcaaaagg tacagaagcg ctactaagtt
    22381 ccttaattct atccataggt tctaaccgtc tagtcattcc tattttatag acatcttcac
    22441 cgaaagatcc gatattactg atgacataaa catagccagc tctagtatta agttctcttt
    22501 gcaatacatc ttctttgaca gtttctagtt ctcttaattt ctcttccagt tctttaattt
    22561 tatcagcata gagttctttt tcaacatcag cactagcttt ttgcatgtat gccattaact
    22621 tagttatctc tgagttaaac tgtcgttctt ctttatcaat gcgtttcttt tcacgttcta
    22681 tttcacgtct taccttttct tcttcaatca tttgttcttt tattgctttt tgctgttctt
    22741 tttcatcgtt aactttaact atgtatgaat agttgagttc taattcttga agttttaatt
    22801 caagtaattc ttttttgaat tctgcttcat cgtttttaaa aagcttgttt attttatcaa
    22861 aagttcttat aattttttct ctagttgaat ctacgttaga aatagtaagt ttattgagaa
    22921 gtccagttat ttctgattct aatggtataa gcattttctt tttaatatta ttagcttctc
    22981 tattattcaa ataagaagga atattaattg caccgtctaa aataaaatcc ttttctttaa
    23041 tctttaataa agaaagtttg ttttttattt cggatgaaga agtttcatct atattcggaa
    23101 taattactga tttatagata gtgaccagag atgtgtcata tttttgatta atttcatcgt
    23161 ctaaccgctg gctttcagca ttaagaatat caattttgtt ttctagcgtt gacaagtttt
    23221 tattcaattt acttatgttt ttctcttttt cagatataaa cgtttcccta gcatttaatt
    23281 cttgagaata ttcctttacc ttactctcta aggcagaagt tttatctttt aattttttag
    23341 cttcagataa tttgctacta cccataatta ttaaaactat tccaactaaa aacaatagta
    23401 ctcccattca aaacgcctcg cttcttttat aaaataattg tcaaaatcat ataaaccctt
    23461 accgaagttg acggctccgg catgggaatt tttttaaaat acaacttttc cgataattct
    23521 aatctgttct ggcgatacaa ttctatcttc gtataagtcg tttatagaac gtaaaatgat
    23581 tgtttgattt tcgtaatctt tatatatctc tttacatgta actccgtcac cacctaattc
    23641 cacaatagca atttccccat cttctacgtc cggttgttct ttaacgaata cgaattgtcc
    23701 attcctgata acaggttcca ttgaatcgcc tataataggt actgcgaagt cagcagcact
    23761 tggaactctc tcaaattctt cctcttcgac aaccgtatca ccgtaagtaa gttctgttgg
    23821 attggcagcc gaagccgaat tgtgaacagt tgggattttt tcttttttag gaaaatctag
    23881 gacattttct tgtttttgtt cttctaatcg attacttgca aattcatagg tagcaacttt
    23941 attttcgtcg ttaagctgat tatatatagg aaggatatta tatatctgat tagatataga
    24001 taaatcaata ttcatcaaat catctatatc aacattgaat atcttagcta tctcatttaa
    24061 ggtttttaat tttggtgtat attttccttt ttcccattcg cttattgagg atgaactttt
    24121 tcttcctagt ttttcggcta gttcttgttg atcaatatta tacttttctc taagaaactt
    24181 tagattttca gcgaacatag taacacctcc ttgagttaat tgtaacaccg tttcggaaaa
    24241 aatgtaacag gtttcttaga aaatatttta gtgtttttaa agaagtattt acgcaaaata
    24301 gaaatcgatt tcaggaaaac tgaaatatgc acttgacttc ggaaaaaccg aagtatataa
    24361 tttagtcaga aagttaaaga gaggaggcga ataaaatatg gataccgcga agaaagaaaa
    24421 atatacattg agacaattaa gagctttaaa gggttattca aaagaagaac tgtcaaggaa
    24481 aagcaaagtg acatcaagaa caatatttat ttacgaaaac gatgtagata aaatgaggaa
    24541 cggaaagtac gccactctag aaaaaattgc taaggcattg ggtgttagag tttccgatat
    24601 ttttttagac cctgattcgg aaaaaccgaa atcaataaca ggtgaaacaa aacaagtcag
    24661 ctaggaggtg tgaatagtgg aagagaagaa tataaaagta ccgactcttg aagaatatac
    24721 aaaaattgtt gtcgaaacag acgagcagaa cccgaaaaca atcgcagtta ttacggcgaa
    24781 tgatattgaa tcatgcgaag gttttcgagt tcgaatgacc cctagatatg attaatgttc
    24841 tttatcacgt ggaggtatag gatcgtttcc aaaactatct tttgattgta tttgtccatt
    24901 ctttttttgg acaataaact ctgattgctg ttttttagaa atctttttac catactcaac
    24961 agcatctgat ttattatcaa atagttttgt atcttcggaa ttaccttcac cacgtacagc
    25021 ccatttgcca tttctaggag atacccattg atttttaccc ataacaattc acctcgcttt
    25081 caagttaatt ctattaagag gtgaaaagaa aacaaactga tggaggtgag attgtgagta
    25141 acaagccaaa aatcactttg aatggcacac ctaatcttca aagattagca gatgaaatgg
    25201 ctagaatacg ttctagacat tggggagtta ctgtggtggc aaccataatt gaacaaaaag
    25261 aaaagcccac acagccggca agcaagtagt gggcaccata gaacaataat attatatcac
    25321 acactcgcca cttccgaaaa gaggagttgc tgctctcctt tcaagtttgc caaagtccac
    25381 gtttcttcat tttggcaact cctcttcttg gaggtggtga cggcgagaga cgaaggaggg
    25441 atgacatgaa ggaagaatca aaaataggga ttttgaatga gaacaattac acaagattaa
    25501 ttattgaaac agaagaaggg gaaaaagtag cagaagttac attgaccgat gcaactcctg
    25561 ctgacggtta tcgtattcga ttaactccta aatatgatta accttttggt gggtgtggat
    25621 cgtttccgtg actatcacgg ctttgaattt ttccatctct gccatgaata aatagctcag
    25681 atccttgatt tttagaaatc tctctagcga tttttactgc ttctgatttt gtattagtat
    25741 gtgcagtcgc tttagaattt ccagcacctt tgacattcca accaccattg gaattaggta
    25801 caacatgttg attttttccc atagttttca cctccatttc tatagaaata ttttatcaaa
    25861 tagaaatgga gaaattcaat aaacgaaagg agggatcaaa tgacattaca agagcatcaa
    25921 cacttgatgc gaaaactaaa tcaggaatac cacgaggaaa tgaaacctag attgctaggg
    25981 gaacaatggc gtgaacgcca gaagaagtgg ttagaaataa aaaagtgact cagccgtcca
    26041 aagcaatgag tcacaaacca aaaattatac ctaaggagat tttatcacat gaataagaaa
    26101 attgaaaatc ttatcgaaga attgaaacgt gaatgccaaa agcaaggtgt ttctattatt
    26161 tgtacagccc aaaaagaagg ggaacttaaa agtctcgttt atggtgagac aacagaaatt
    26221 ttactttgtc ttgctatgca agaagaacat ttagatgaaa atctcccatt gtcagcacat
    26281 attatgcgta gaattgctgt ggatgcttac gaacaagcga aaaatgaaga agaaaatcaa
    26341 ccttcaaatc atacttttgt tattaataac aaggaagatt tagctgatgt gatgactcgt
    26401 attctcaagg gggaatttca atgatgaatg aaaaaacaat tgatctactc attattttat
    26461 ttttcacgtt agtgattgta gcgaaaagtt atgtaatctt tggcttgtta ttcgcaatta
    26521 ccatgcttgt gctttgcgtg ttagcaagca gaaaagaggt taaacatgaa cgagttagca
    26581 aatcttgaca actatttaac tgatcctgat tatgctaaac caccatatga agcgccaatt
    26641 gatgaggagg atgaagatga gtaaatctac cttagaaatg agccatcaag aatggctcga
    26701 agaccgcaaa agaggtattg gtggctcaga tgttgcaacc gtacttggat taaacaaata
    26761 caaatctcct tatcaattgt ggcttgagaa aacgggtcaa attgaattga aagatttaga
    26821 aagcgaacca gcttattggg gtaatgtttt agaagaagtg gttgctaaag agtttcagga
    26881 acgtacaggc aaaaaagtac gcagaagaaa ccaagtattt gaacatccat tacatccatt
    26941 tttaagagca aatattgatc gggaagtagt gggagaaaat gccattctgg aatgtaaaac
    27001 agccaatcaa tttctcggaa aagagtggga aggtgaagag gtaccgctta gctatctctg
    27061 tcaagttcag cattacatga acgttttaaa caaagactat tgttatatcg ctgttttgat
    27121 cggtggacaa aaattcattt ggaagcggat tgaacgagat caagagctga tcgatacaat
    27181 cactgaacaa ttagtagagt tttgggaaac gaacgttctt ggaggtatcg agcctgtaat
    27241 tgacggaagt ggagcgactg ctgacttctt aaaagaaaaa tatgcagatg tagaagaaaa
    27301 tcaaacagct ctaccatcac gttttgatga acttatcgag caaaaaagag aactcaagcg
    27361 gacgaaaaaa gaaattgaat catctattcg tcaagtagac aacgagatca tcagtgagct
    27421 aggtaaacgt gaagccagta tcggtatcac acaaagaaac attatcagct ggaaacttgt
    27481 tcgtacaaga cggatgaaca cgaagaaact agcagagaaa tatccagatg tcgcaaatga
    27541 tgaagagatt tataacgtta ctgaatcaag aaggctaacc gaaaaggaga tcaaataata
    27601 tggcaacaaa tgaatcgtta aaaaatcaat tggcagaaaa gccacagaaa caagttgcac
    27661 caggacagtt agggcttaaa gctctaatga atacaccaac aatgagaaag aaatttgaag
    27721 aagtacttca tgacaatgct aatgctttta tgtcgaatgt tatgactctt gtatctaatg
    27781 acagttatct tgcagatagt gaaccgatgt ctatcatgag tggtgcgtta actgctgcaa
    27841 cattaaatct tgggctagat aagaatttag gttatgcata tttagttcca ttcaatagta
    27901 aaaacaagca aacaggaaaa tgggaaaaga aagctcaatt catgcttggc tataaaggat
    27961 atatccaatt agcccaacga tcaggtaaat acaaagcatt aaatgtgatc gaagtttacg
    28021 aaggagaact aaaaagctgg aaccgactga cagaagagtt tgagtttgat ccaaatggta
    28081 gaacgtctga tgaagtcatt ggatatgttg gctatttcga gttactgaat ggattcaaaa
    28141 aaactgtcta ttggaccaaa caagaaatcg aagctcatcg gattgctaac aataaagatc
    28201 gcgataagac aaagttaagt ggtgtgtggg catctgatta caatgcaatg gcacgaaaaa
    28261 ctgttttgag aaatcttctt tctaaatggg gaatcttgtc catcgaaatg caagaagcca
    28321 ccacatcgga tgagagagtc caaagggttc aagaagacgg cagcattatt gctgaaacag
    28381 aagttgaaga agatattcct gaaagaaaag aagcagaggt tatatctgaa gaaaatgaag
    28441 atgtacaaac tggattattt gatgcatcta atccgccgtt aaacaaataa tgagggagct
    28501 ttctcccttg cttttctaga ggagaaatac gaatgaacac aggatatgtc aaattacatc
    28561 gaaaagtgat gaattcattc gtttggacca atccttatat gtataaatta tggagcttgt
    28621 gtttgatgaa agcgagtcat gagaatcgca agatactttt taatggaaaa gagatacaag
    28681 tgaacagcgg agaattcgtc acagggcgcg atgctatcac atctgagatg aacgaaggcg
    28741 tgaaacgtga acatcaagtg aacagcggtt ctgtatggag atggctaaaa caatttgaaa
    28801 aaaacggaat gttgaacatc aaatcaacta cgaaatacag cgttatatca ataaaaaact
    28861 ggtctttgta ccaaagcagt gaacaacaaa tgaacatcaa acgcacaaca agtgaacaac
    28921 aagtgcacac aaacaagaat gaaaagaatt ataagaatga aaagaataat aaaacatcat
    28981 cgtcgcaacc acgcaaaaag cgtgtttacg acaccgactc agtttactac attctcgcgg
    29041 aggagttatt caaacagatt tgtcagaatc aggaaatcaa aaagccgaat ctgcaaagtt
    29101 gggcagataa cattcggaaa atgatcgaga tcgacaagcg gaccgaaaac caggtacggg
    29161 gaatgattga atggagtcag cacaatgtgt tttgggcatc gaatatttta tctgctaaaa
    29221 aattgcgaga aaaatacgac acaatggcag cgcaagcaaa tcgtgattat aaaacaaaac
    29281 aaactaaaac gcttgaatac gagaaattta gcacagatga gttgcctatt tgagaggagg
    29341 cgtaggcatg gaaactgttg gggaaatcat ggaaaagctg atacagaaag tgcttgtcca
    29401 acgtggcgaa tgtcctgaat gcggacagcc tttgtatgga tggcgtacga agaaccctga
    29461 tggctcagaa cgttgtaagc caacctgtat gcaatgtggg tataaagcat tgcgagttca
    29521 ggaagactta caaacagaac gaatttacaa cgagagcctg aaagcaagag caatcaattt
    29581 tttcaaaggt ggttctgttg tgcctaatca agcgttgttt gattgcacat tgcagaatta
    29641 tcaaattgtc gatcaagaaa caagacaagc ggttgaagta accaaacgct ttgttaattc
    29701 agtcttgtta ggaaatccaa gtcaccttgt tttaactgga aaacaaggaa caggtaaaag
    29761 tcacctagcg atggcagcgg cttgggaagt cttgaagcga tcaaactacg ataaaaaaat
    29821 cttatttatc gggttacagg aaatgctgga tcaaatcaaa ttttcgtaca acaatcctga
    29881 actcagaaaa acgattgagg gatcgttgat tgcagatatc aaaacagcgg atttagtcat
    29941 cattgatgat atcggttcag aactaggaaa agatgcatca gatagtcgag cgtttggcat
    30001 aaacacgcta aattcgttct tggatgcacg acagaaccta gcaacgatta tcacaacgaa
    30061 cttgcttggt gaagaactga aaaaagctta cggtacgaga acaatatcaa gaatgtttgt
    30121 caactctgat ggatttacga tggtattttc tcaaacagca gacaagcgca taaaaccagt
    30181 gaaaggtagt atcgcatgaa taaataccgt aataaaaaaa ctgttcatcg aggtatcaag
    30241 tttgattcta tcgcggaagc agagtattac gatctagcct tgtggcaagc tgaagcgaat
    30301 ggttggaaag tgaagctcca ggaaaggttt gagctgatgc cgaagtttga actagagggc
    30361 aagaagtatc gcaagatcga gtatattccc gacttcacat tttacaaaag cggcaagctg
    30421 gtcaaagtcg tagatgttaa ggggatgcag acaaaagact ttaagatcaa ggcaaagttg
    30481 ttctgtcatc aatatcaagt gccgttgata ttagccaaaa aatatcggaa tacgttcaag
    30541 gaagagcgtt tttaacgagg tggtccatca tgacaacaga agaagtgatt caaatgcgaa
    30601 ttcgaagcct tcggcgtgag attgacgatc tggaacgaac aaaggcagtg atggtcaatg
    30661 aaacggctag aaaggcaatc gatttgcaca tagagaattt aagaagggaa atccgtagat
    30721 tggaggaatg agcgtggata aggaagcggc ttggcgaaaa ttaatgttgc tgattcaaga
    30781 tgagaactgg caagaagatg aagcagtggt tgctgaagtt cagcgtctag gaaagattgc
    30841 taacggacgt atacgaaaaa agccagacaa aagaaaacag cgcaaaggga aaatcgtcgt
    30901 tgttttacac gaaggcaaaa ttttgatgca aggaacagct agtgagctgt ctgcagaaac
    30961 tggatatacg cgtgggacta ttcgaacgta cgcttggcga aatcacaccg atcgaaaagg
    31021 gcacgaatat aagtatttgg aggaagaaaa atgaacgaaa acaaattaat caaattgggt
    31081 gtagcaggag cagtaatcgt aggtattgga gttatcggag gatttaagtt cttcgaaaaa
    31141 atcgataatg gatatgtggg tgtgcgctat tcaatgaacg gcggtatcaa agatgaagca
    31201 ctgacgcaag gtgtgaaatt tgtagggatt gacaaagtga tccaatatcc aattcgcttg
    31261 caaactatcc aatcaaaaaa tatttcagta tctacaagcg acggcaaaaa gacaacgatt
    31321 gatatcaaat atgactacaa agttgattca actaaagcag caaaaatgta caaggaattt
    31381 gggaatatca cttcggaaga tatcgaaagt ggatggttaa aatctaagct tcaaaaggtc
    31441 gctcgtgaag tttatgcgaa atatagtctg cttgatgtcc tttcaggaga ttcctctaaa
    31501 gttgaagctg aggtattaac gaactttgct aaatcagttg aatctaaagg gtttgaagtc
    31561 gaagacgtaa cacttggtgt tccagatgtc gataaagaaa cacaaaaatc aatcgatgcg
    31621 atcattcgag ctggtcaaga aaatgaaaaa gcgaagctag acgcagaaac tgcaaaaact
    31681 caagctgata gtgaagctta caagaaaaca aaagctgcag aagcagaggc agaatctaat
    31741 cgcaaagtcg ccgaatcagt aacagacaat ttgattcgtt atgaagaagc tcaagctcgc
    31801 aaaaagcatg gatgggtaac agtaaatgga gcagatactg tagttacgga tgaagcaggc
    31861 aaataatatg ggattcttta tggctaaaat tctcttgttc ttaggtttag taggagcagc
    31921 atatctcgtg tatgcgctcc tttcccaaac tgatgacaaa gaagatgaca acaacgatga
    31981 aatgaaattt taggaggaga aataatggac gaactaatca caaaagtaga gcagtgggct
    32041 aaagacaagg gactggatca agcagatcca aaagcacagt ttttgaaagt agctgaggaa
    32101 ttcggggaaa tagcttcggc gatggcaaga agtaatgatg aactatttaa agatagcgta
    32161 ggagacgtta tcgtcacgct gattatcctt tccatgcaaa aagggacaaa cgtacaagag
    32221 tgtttagaaa tggcatacaa cgaaatcaaa ggacgcacag ggaaaatggt agatggtgta
    32281 ttcgtgaagt cgagtgattt ggaggatgtg aaatgaaata cgaaatacca ctaagtgaag
    32341 cgggcattca agcaattatc aatggtcggg aggttaacat agaacttcct gatggtactg
    32401 aattagtcat cagacaaagt tatttgaaag atatggcagc tccagtatta attgatcgtt
    32461 ttaacgtgac tgattctgtg gtagagaacc acttaaaaga atttcgatca agtatagacg
    32521 acactttcag attagggagt tgattgacaa tgaacaacag acatcgcaga ataacaaaac
    32581 taagaaaaca ggaactgaat gtactaaaga caaagtttga aaaagaatat ggaatttcag
    32641 cagaagaaac atataaagtg gcaagtcagt ttgttgctga tgcaagtgat gctattcgta
    32701 agtttgggat ttcgatatta aatgatgatc gtaaatggga ggaaatgaga tgaaactaaa
    32761 agacggattt tacgctagta gtcacggcat cggcggttta atgctagata tgccgacaaa
    32821 gaaccctaaa acacgtaaga aaccaaaagt caaagtcggt gacatggttc gctgtgaagc
    32881 agaagagttc atttatccgt ttcgtggata tgtagaacac gtctataatc actcagcgat
    32941 cattcgtatt gaaaacacaa tggaatgcga taagtggtta gcgaaaagca aagagaattt
    33001 agctgtagcg agattggtgg atatggaggt tataaacaat gaagtttaaa atctttgaag
    33061 aggacactcg ttataaatta gaaaaagaat taaacgattt tgcgaaaaac aatgagattc
    33121 agcatatatc tttagcaact tctaagagag gttatgcaaa ttactatgca gctgttgtga
    33181 gctatgtaag tcgagaagtg taactcggca aataaaaaaa gccggatcgc tccgactgat
    33241 tcaataaatc caacacattt attatatcac ataaaggagc ggtttgactt gatgcaattg
    33301 ttacgagagg tagatttcaa acagacaaga tgtaatgcga gagatgtgct gaagaacttt
    33361 cggcgtttgg agcggatggc aggtcgctct ttgatagata ttaagtcgcc gattattacg
    33421 gatatgccga aggcaccgaa gcacggcaat aaggcagaag acgcgatcat tcaaatgatg
    33481 gatatagaag cggagagaga cgcgattcta gtggctttga tggctcttag tctgattagt
    33541 cgtcagatac tctactacag cttctgtgtg ccagacagct tctcaaacta cagaattagc
    33601 cgtgaagtgg gttattcaga aagaagtata caacggatga aatcggaagc tctaatagag
    33661 tttgcagaag catataaaca cggaagaata attgcttata aataggggga ccatataatg
    33721 tggaaagatt atgtatcgtt gaaagagttg aaaaaagatc ttgttttcaa aagaattgta
    33781 gaatggtcag agagtgaatt aattttagaa gatggaacca aaatggaagt tgtatgtagc
    33841 gaatcagatt gctgcgcatg ggccgaaggt gaattcaaaa atgtaaagct tgatgcagtg
    33901 attacagata taaagatttt tgataaaggt aaccgtctct ataatggtga cggacatacc
    33961 tcttatgctg aagtcgttgt ttatcataat cgtaatgaga tcgctaaagc agaatgcaca
    34021 gcgaatgatg ggaatggcgg ctactattat agtgtttgtg ctttaaaggt caaagacaaa
    34081 ctttgtatag tgactgacgc ataaaaaaat ggcggttttt tggcggaatg atggcggttt
    34141 ttagccattt atcagtgata ttatggtagt gtcgaaagat tagtgatagg tctgagacaa
    34201 aataataata aaaggaacat cgttttatta ttgtttcaca attaagcttc gatagacagc
    34261 agcggaaata ttaagaataa ggatgtgaat tttaactcct tctaaattgt tcttattatc
    34321 tatcatccgt tgctgtctat tgttacatac agatcgctta ggcggtcttt ttattttggc
    34381 cgaaaaccta cattttcgat ggccgattat tggaggagga atagcatgtt caaactatct
    34441 gaaatcatta agaagtccga cgttgagaaa ttagagatgt taaaaaagaa gttgaagaaa
    34501 tagcagtctc ttcgtgaggc tgttttattt tgctcacaaa aatagaccac tatcgggtaa
    34561 tagtggtcag gaattaaatg aaaaagatgt tagggttgtt agctaagtat aacatcataa
    34621 cgcttacaaa acaatgcaag aaggataaat tattatgaga acttactggt atgtgtcatt
    34681 aaacaataaa tatccgaagc caatgaaagg acagcatagg cgtgtagtca tgtctgttca
    34741 aatgaaggcg aagtattcga ttgtagaaat gatcagagag gcaacgccag tagagattga
    34801 ttattgcaag ctagtctatt gtgggtgcgg ccgttggaaa gaggatcatg tacaaaaaaa
    34861 tatcagcaag tacatataga gaggcggtga ttaaggatgg aaaaaagcga tacgaaagcg
    34921 aacagataca aacctactgc tgcagagaaa aaactcttgg aagtattgat aaatccagat
    34981 aacttaggca aaccggtgca agagttgtgt tcactggcga aaataggtag gaccaaatat
    35041 tacgacgcca tgagcaaaga tggctttgtt gatctagtta acgaaacaac aatggatctg
    35101 atcaaaggaa aagcttctga tgtccttaat gccacttaca agtatgcatt gactgaaaaa
    35161 ggtcatcagg ataggaaaat gattctgact attgctggaa tctatgcaga caaacaagaa
    35221 ctcaaacatt ctggcggcgt cgatatccga aaacagtatg agaaaatgtc cgatgaagaa
    35281 ttagaagagt tggtgaaacg gtatgaaaaa atcaacgact cttaatcgtg ttgagtatgc
    35341 cgttgttcaa agagagctag ccattcgaaa agctaggaaa agtttttggc tattctgcca
    35401 gcttctttat ccagagtttt acaaagatga tcggttgtat ttgaaagatt tatgtcatac
    35461 gctacaagat ttttacgaag ataaaatcga caaaaaaatt ttggttatta acatgccgcc
    35521 tcgacatggg aagactttta cagcgcggct attcgtttta tggatgtttg gacaaaatcc
    35581 aaagacgaaa attattaccg gatcttataa ccaaatcctg tcatctttat ttgcgcaaca
    35641 aacacgtgat ggaatcatgg ttgaaaacga aaatgttaag gctgaatact ttaaagatat
    35701 ttttccagag gtgcaaatca aatatggaga tgctgcaaag ggtttctggt ctttagatgg
    35761 ttcagaagaa aagaattatt tagcgacttc tcctggtgga acatccactg gtattggcgc
    35821 gaattatgta attgttgatg acatcattaa aaccgcagaa gaagcctata acgagcgtgt
    35881 tttagattct cactgggaat ggtataacaa cacgttggcc caacgaatgg aacggccacg
    35941 taaacagata ttgattatga cacgttggtc aagtaatgat ttagccggaa aaatgttgac
    36001 gagacgaaaa aataatgttc atcagatctg ttataaagca gtacaagaag acggctcgat
    36061 gttgtgcaac gagattatga cccacgatga gtacttagat gtggtacaag aaatgaatgt
    36121 agatattgca gaagccaact atcagcaaga accaattgac caaaaaggca ggctatatca
    36181 gaagtttctt acttatgata cgttgcctga taacattatc aaaatatgga actacaccga
    36241 caccgccgac aagggtgccg attactttgc gtctcctgtt tttgctgaga cgtctgatca
    36301 tgatgcttat attatcgatg tcatgtatac aaaagagccg atggaaacaa ctgaaatagc
    36361 ccacgctaat atgattattc gcaatcgagt taataaggta cggattgaag gaaacaatgg
    36421 cgggcgtgga ttcagaagaa attcagaaag aattacaaaa gagcgaggct atcgaggtgc
    36481 agtatttgaa gactttcatc aatcggataa taaactgtct agaatactgg cgaatagtgc
    36541 ttgggtggaa aatcatgttt actatccaga tgattgggcg acacgttggc cggactttta
    36601 tgaggctatg gttagttatc aacgtgaagg taagaacgct catgatgatg ctccggatgc
    36661 agttacagga attgcagaaa cgattataga agcagatgac ttcgagttta ttgcttatta
    36721 ggaggtgggt ctttgtttta ttctggaatc acattgaaaa aatacaaacg tttaagaacg
    36781 aaatattcaa cgcaaatcga agaaggatta ttcgatccta acgcttttat ggaagatatg
    36841 aaaccctttt tcgatgatcg agaaagaaag tatcttgctt atactagcga gaaaaacgag
    36901 atcgacagtc gtgagaaacc aaaaacaaaa atcattaagg tcaataacaa gattcatgcg
    36961 ggaatgtatt cagtggtcgt tgatcaagca gttaaccatt tcacaggaat accaattaaa
    37021 tgggattatg atgtttcgga acagaaaagg acattcattc aacgaatgag agacaaatta
    37081 ctgggtaatg atatcagcgc cccttctacc ccagaagaat ttgaaacact cacgagacaa
    37141 ttaagtacta tgcggtttgg aatgttagac cccgatactg caacatttca aggagcgaca
    37201 gggcttgctt tcagattact ggagcctgtt gagacaaatg atggttggga actaagagca
    37261 agcaacattg agccgtggaa agctgaaaag tacgaaaacg gcgcagtgta cattaaagag
    37321 aaatacgatc catatcaaaa gaagttttat gaagagatga aggttgtcac gccgaaatca
    37381 atatttactt atgctcgata tactgattac cctggcacgg tacaaggagc atttaaaacg
    37441 ctgggtaatg ttcctaatcc tttaggcgtt atcaatctta cggagtttaa aaacaataca
    37501 aaccgttact gtgactttga agttgcagag gagattagtg atgctattga tcgtgtttta
    37561 tctgatcagc agaacgagat tgaacaattc aagttagctt atatgctgat cactggggca
    37621 gatttgtccg aggataaagc caagaagatg atggagcaac tagggatcat caatctgaaa
    37681 gaccctaatg cgaaagccgg ctacgtgaca aaggatctac aaaaggattt caacgagtat
    37741 cattttgatc ttcttaaaaa gcaattctac acggtgtgta aagcaattga tttcaatgac
    37801 gaagtcttta agtcgaatag ttctggggaa gcccgaaagt ggcaaatcat tagtttagaa
    37861 gctaagacaa ataccaaaga acagtacttt cgagaaggat tgaaagagtg tgccgaggtt
    37921 atggctgctt atttggattt tgccgagaaa gttacaattg atccggaaaa gatcattttc
    37981 accttctctc gttcgcttcc aacagattta agctacctag ctgaggcatt gcctaagttg
    38041 gcaccatacg tttctaagag gacgattcaa agtcagatcc cgttcgtcac agatgttgat
    38101 tatgaaaacg aaatgattga cgtcgaaagc agacaatctt acccagacgg cgagtatgga
    38161 ggtggcatcg ttgagtcaaa tagaaacgaa gtactggacc aaacgtcgag aactggaaga
    38221 tttagcaaga ctcaaaatgg aaaatcaaac gctaaagaaa ctaagtagtg tctttcctga
    38281 tgcgttgaaa gaaattcaag cggagttatt atcccaagct gatttacacg atattaccta
    38341 tgctgagatg atggaatttt atagtacaag tgatcagaaa aaatatcgtg aatacgttga
    38401 aaagaactac aaatcactga agatgtatga tgcaaaatac aaagagttca tcgaagaata
    38461 ctttccttct ttcgactacg ccaaagtgaa tcggctgctt caaatgaggt cagatatttt
    38521 tcgaattctt gcagagagtg caatagatgc agatgtgaat aaatattttt cggatcggtt
    38581 agaagatatc ttgcaacgtt cgtatgtatc aaacgcaaac gtatttgccc agattttgaa
    38641 cgtagatttg ccgaattact tatcaaagga agaacttgaa cgttacctga actatccttg
    38701 gtcaggtaag acattctcgc gtcgtttatg gggcaatatt tcatctctag aacaaaagct
    38761 atctaacgcc attacaacta gtgtagcaag tggcgaagga gttctcgtgg cattacgaac
    38821 aatgcgagaa gacccagaaa tatgcgatat gttcaaaagg gaggaatcga agtacaacaa
    38881 ggcgatcgaa aatcttgtga gaacagaata cgctaaattc gctcaagatg gtattgagaa
    38941 atcttatatt gaaactggcg tagacgaata caatgtctta actgcaaaag atgaaaaggt
    39001 atgttcaata tgcggtggca aagcaaagaa caacccatac aagttgagtg aagcgatcat
    39061 tggtgagaac cgtgcgcctt ttcatggccg atgcagatgt acagatgttc ctaatatgcc
    39121 gaaattagga aaagatattg acgaagagta tgagcgttta tttggcgatt tattagatga
    39181 gtttgcacat gattcttttg gaattaattt gaaacggagg aagtagaatg aaagattttt
    39241 ttgaagcagt actaacaatt aatgtaaatg ctgatattgc agaagcctac aaaacagcta
    39301 ttgagtctga gaaccatcct aatggcttga gagaccattg gaatggcaat tatgcctacg
    39361 tggttattgg cgatcaaact gttaattatc aagataatac tccagttgat aagaataccg
    39421 ttaatttaac gattcaatta ttatctcatt cattaccaaa tttaaaagaa acagttgatt
    39481 ggtatgaaaa tatgggatgt attgttgtta gaactgacta caaagaagga aagtctagta
    39541 attaggcttt tttattttgt ccgaaatgac gttaaactag cgcaatactg ggcttggttg
    39601 aatggtgggg cgcaactatt aaaactcaaa gcaatgcggg gcgtgaaaac gaatcgtggg
    39661 gcgaaaggag aatgattatg aaacacaaat cattaatgcc aatgaatttg caatactttg
    39721 ccgaaggtga cgatcaaaag ttttcttttg atgacttcaa atcttttgtg gaatccaatg
    39781 aagaagctca aaaatttatt cagtcacaat ctcaaagtgt tgccgacaaa caattggaag
    39841 cttggaaaca aaataactta gataaaatta aacaggatac catcaaggaa tatgaggaat
    39901 ctaagaaaaa caagtcacct gagcaaattc aactggaaaa actacaagct gaatttgaag
    39961 cagaaaaagc gttgcgtgtg acaagtgata ataaagcatt tgttgcagaa caaattgctg
    40021 gattagaact agatggagag ttaaaagagt ctatttctca atttatgcta aataatcttg
    40081 ttagttcgga tacagatttc actaagaatg ctgttgaagg ttttacaagt gttttgaatg
    40141 caattaatga gaaacatgca gatgcattaa aagaactaca aatgaagtct gcatttggtg
    40201 gaactcaaca atcgaataac caggttcagc agaacaatga aacattaaca aatccagaag
    40261 aacaattagg acaaattctt caacaattta actaggagag tgaaaaatta tgaaaaaaac
    40321 atctttaaat aatttagagt atttggatat ttcaccagcg attaatgcta tgcaagtacc
    40381 aaatacacct tttttaagct atttacttgg tgctggaaaa acagagccag caaactcgac
    40441 agaaattaaa tggcgtgaat atgatatcaa caacgatgat tcttctgaaa aacttgaggg
    40501 cggagaatat ccagatgctg aatcaggtcg aacttggttt aacaactata ctgaaatttt
    40561 tagaaaatca acctctgtat ctggtacatt agatgctatt aatgtgaatg gagtcggaaa
    40621 tgaattaact aatcaagtag cactacgtgg tatggaaatg aaaattgatt tgaaccgaaa
    40681 attgattact ggtgtaaaag ctgatgaaaa tggttctaaa ggtcgtcgaa tgaatgggat
    40741 tttgaacttg atcaattcag caaataaggc agaaacagcc actgcgggtg cagtaacaag
    40801 aaaagatatc gatactttat ttaaattgat gtatgaaaaa ggttatatgg gagaaaaact
    40861 atgcttgatt tctccagata tgcaggagtt aatgactgat gagttagatg gaaaatcaac
    40921 aaaaattgtt cagttcgggg aaagagtaac ttttggattg caaattggaa atatcgtgtc
    40981 taattacggt acaggtattg ctctactaga accatcattg ccaaaaggaa caattgccgc
    41041 aatcgatact aattatgtga aactacgtcc attacgtgaa tggagagcag aagaacttgc
    41101 aaaaacaacg gattctagac gtatcggtct tgtaggtgaa tactctcttg aatacaatgc
    41161 ttcaaactct ggggcaattt taaatttaaa gtctgaataa aagggagtta gtactccctt
    41221 ttttgatagg aggaattaca gtggtaaaaa aagatgaaac taaaaaagat gaagtcgtga
    41281 aatatagagt aggtaaaact aaaaattttg ttgggtttgt tcatcctaaa actcgtagat
    41341 ttatcacagc agattcaaat aacgaattta tcatttctat agatgataaa gaagcaattg
    41401 caattttgga agatgcaatt gatgttaatg aaatttagga agtgatctga tggatgaatc
    41461 gctaaaaacg gaaatcattg agtctacaaa agaagatttt ccagatttga gtgaagaacg
    41521 cataactaat ttattagaaa taattttgct agaaattgaa tcatacaaca cttgtaaaaa
    41581 tgatatttca tgggaaaagt taaaaagcgt gattagtgaa gtgttgtata aaataataaa
    41641 aaatgaatca gaaaaaacag tatcttcagt tagacgtggc gatacaacga ttagttatgc
    41701 ttcaacaaca aatgatgtta gtgagttact tctaggctat ggtgatttga tacgaagagt
    41761 tattggttgt ggaggattgg agttttttta atgaatgaag cagatatttt agaaactact
    41821 tatgaagata gttgtattat tgaaagactg acggacattg aagattctaa tacaaatatt
    41881 actattcaag attacaaaaa agtatatgat aatcctattt cttgcgctct ttcacaaggt
    41941 caaatcgatg gactagcagt catagaagat ggagagatgg taaatgtttc aactgacaca
    42001 tataaattat ttgttcatcc taagattaaa ctaaaaaaag gagatcgaat aacaataact
    42061 caaaaggcca gtggcttaat tttttctcta tttgctacta agccttttta ctatcctagt
    42121 cattgtgaag tgaatttgat aggaagtgag aaaaatgggt aatctcaaat atgaatcaaa
    42181 tgcagaaaag atcattgaga attttaaaaa tatgactgta attgctcaaa aagaaggaat
    42241 atccttcgtt aacgattcaa tgaataaagt cgttagttta gctaaaccat taactcctgt
    42301 aaaatcaggt aatttaaggc gaggatatcg tgtagtaaaa gctagaaaac tatcaagcgg
    42361 tcgaattgtt ggagcagtta taaacaatga acattatttt aaatatgtag aagaaggtca
    42421 taggactaaa aatggtggct ttgtcaaagg gaaattcatg ttaactcgtg caacgaatct
    42481 tgcaaatatg tcttatattc ctcgaagatt taaacaaatg gcaataaaaa tcgttaagaa
    42541 aggaaagtaa catgaaagat gaaatcattg ctgcaatcag tagcaaatta aaagaaatct
    42601 atcctgatgg gacaatatat cttgattcag ttatgcagtc aactaaagat ttttatttcg
    42661 ttttatcagt aatggaatct ggaactgaaa atgtaggaat tgatattcaa aatgtttctt
    42721 tcttaattga tattgcattg attgataata aacctaatag aaatttaatt aatgaattag
    42781 tctcacgttg tgggactttt tttaatacga ttacaatcga tgagcaaata ttatttccaa
    42841 aagcctattt acctgatgaa gcagatggtg ttcaacatat tcgttttaca ttagaatttc
    42901 cacaatatat tgaatggagt gaaagataaa tgggagaaaa aagaagtaaa accggaatta
    42961 tttctgtcga aaaacctact tggtttcctt tggaagatga gacagggaat ttcccggtat
    43021 atggtactgc gttgccaatg ggaacagcag taagtatcaa accaacagct aattatgaaa
    43081 caacacaaga ttatggggat tcagtggttc aagatcaatt tacagctttt ggtggtgcag
    43141 aagttgaact ggaagcaaat ggatatactc ataaagtttt atctacaatt actggaggga
    43201 aaattgttaa aggtggtgcc ttgcgttctg gagaagatat tgcgcaagat ggtgcgtttg
    43261 catatagacg taaaaaatcg aatgggaaat accgttatac ggtcttttat aaaggacagt
    43321 ttgctctaga ttcagatgaa acgtcaacga ttgaaggaag taaagtaagt tttactcatc
    43381 caacttggaa gggttcattt gtagatgtac caggacttgg atatatgtat tcagttgatg
    43441 aagatgatga aggcgtggat aaagcaatga tcggaaattg gtttacaaaa gtagcaattc
    43501 caattgaaga agcagaactt tcaggaggta cagaataatg tcaaaatatc aaacaacgat
    43561 taaattaacg aaaaaagatg aagaaggtaa atatgagcaa gtacaattta aatctgctga
    43621 atttttacca ggaacagttg tagaagatgc tgcaggagtt atggaagaaa tgcaaacagc
    43681 gactgataaa caatcagtta aaaaagcttt aagtcgtgct tattcattta ttgcagatac
    43741 tttatttgag ggacaattta ctggtgaaga ttattgcaaa ggaattgatg ctcgtgagat
    43801 tgcctcattg acaggaaaat tattgaagtc tgttactgca ggttttgatg aaacttatac
    43861 agagacgaaa aaaaagtaag tgaggcgctc aagtcacctt catttaagta ttcgattact
    43921 taccgagaat tagatataaa gacgcaatta ctcgaagcag gttggacgtt accagaaatt
    43981 gaacgtactg acttggatga gttaatgcgt ctttttgctt ttagagatgc ggtaaaagag
    44041 catgaagatg ttgagtacta tgataatttc actcaatttt aggaggtgat actttgaata
    44101 acgatgacct aattctgaag atgatactag atgaatctgg ttttactgcc ggtatgaata
    44161 atgctgtcaa aaagttgaac tcttttgatg aaacaatcga aagaaaaagt agaaatagtg
    44221 gcagttcatt aggtagtatt tggaaaatat ttgctggaag ttttctagct agcggagtaa
    44281 ctagaatcgt aggagctggc tttgatctaa tcaagggttc cataagtgga gcggttgatc
    44341 gagtagatac gatgaataac gctctacgaa atttccaaaa tatgggattt agtaattcag
    44401 aaattatgaa gaatatcgga aagaatgggc ttttatctca aggtattcaa ggacttccta
    44461 ctgctttgaa tgatgcgata agtcatgttc aacttcttgc ttcttctaca ggtgatttaa
    44521 ctcgttcaac tcaaatattt aaagctttaa atgatggaat tcttggtttc ggtggttcaa
    44581 ctgatcaagt taatgaagct gttattcaat tatctcaaag tttctcaaac ggaaaagtag
    44641 acgcacaaac ttggaactca atgatcaacg ctcaacttgg acctactctt tctgctattg
    44701 ctaaaaagat gggaattaca atgggagatc tgaaagaagg tttgtctcaa ggtaagattt
    44761 ctgttgaaga attccaaaat caattaatag aaatggatac caaaggtggc ggaggactta
    44821 aatcattaag tcaaatcgct aaagattcta ctaagggaat taaaacctct atacaaaatg
    44881 caaaaacagc tgttacacgt ggtgttggtg aggtaataga aggattaaat aaagcattag
    44941 tagattcaga tttaggtgga tttaagggaa ttattgataa agtgggcagt tcaatggaat
    45001 cgttcttaaa agtaattgct gcaaatattc ctacagcagt atcattttta agtaatttat
    45061 ttaacgaaat tcaaaaattt ggttctgctt tgaaattcat gatgcccttt cttgttcctg
    45121 cagctaccgc ttttggagcg ttcatgtttc aacttaaagg tataccagca ataataaaaa
    45181 gcttcaataa ttttaagaat gccataattg gcgttggaaa ttcattaaag attatggggg
    45241 caatagctgc tgctaattca tttgttttaa ttattggtgc agtcgttggt gcaatagctg
    45301 ttttcggtta ctttatggca accaatgaag agtttagaaa caaggttata tctatttgga
    45361 atgatgtgaa agattccgta attggtgtat taaaaaatat aaaggactgg ggaattgata
    45421 cttggaattc tgctaaagaa atggcatcaa atgcagttga gggtgtcaaa gatgcttggt
    45481 caggaacaaa ggaatggttt tctaacacct ggaaaggtat taaggatggg gccacaggtt
    45541 tatttgataa aacagtagag acttcaagaa atgcagtcga tagtgtaaaa aatgcatggt
    45601 ctaatatgaa gaaatggttt tctgatactt ggcaaagtat aaaagattca gccagagaaa
    45661 aatggaatga aattaaaggt tctattatgt cggttgctgg tccattgatt acaggtataa
    45721 agaatgcatt tttacatgtt actttttatc tagagacctt atggaataat ttagttgaga
    45781 ttggtaaaaa cgtctttgag attttaaaaa atgttatact tgcgccggtt ttgtttatta
    45841 cctccatgat ttctggtgga tgggaagaaa caaaaaataa tatgattgct gtttggaata
    45901 atattaaaga aagtgccata aatatttggg aatctataaa gaatatattt gtaagttatt
    45961 ttacaaatat ttattttgct gcactcaata tttggacagg gttcaagctt acattgataa
    46021 atatttggaa tgaagtggta aatcaagcta aatcgatttg gttaaacata aagtattttt
    46081 ttattaatct ttggattgat ataaaatatt ttgcaattca gaaatggatt gaattgaagt
    46141 tttctattat tcaaacttgg atcgatttaa aatataatgc cattactact tggaataata
    46201 ttaaacagtt tttcaaagat acttggaaaa atattaaaga tacggcatac aatacgtgga
    46261 tttctataaa aaataccatg attaatacat ggaataacat taaggactct ttctggaata
    46321 ttgttactgg aattgttaat tctgctgaaa atgcatggac aaatctaaaa aatggtgttt
    46381 caaatgctat taatcgggta aaagaaatct ttaattcgtt aagggaagtc aatttatttg
    46441 aaattggcaa gaacatcatt gatggactta taaatggtgt aaaagaaaag tggaatgctt
    46501 tgaaagatac tatcaaaggt attgcaggta atatcaaaaa ttggattaaa ggagctttag
    46561 atattcattc tccatcaaga tggatgcgtg atatggttgg taaaaatatt gttcaaggta
    46621 ttatcgttgg tattgataaa gagcaaagta agttagatca aaccatgaca aatttagtaa
    46681 aaacaccgtc tgttcaacct gtagtaaatg gaataagtca cctaccaatt acacaaacaa
    46741 agcaaaatat atctgctagt gaaacaaaag aaattcattt acatttaaat gtttatggag
    46801 atttacctga ttcaatggtt cggaagatta ccacaaaaat taaaacagaa ttgacaagac
    46861 aaatgaaacg agatgctggt gcagtaggag gaacattata tgcaacttaa gagaggacaa
    46921 ttttttatta atcaacatta ttcttctgaa tttaatgtgt atattcaaaa caggcctgct
    46981 tctgtttcag ctagtcgagt aattgaattg agagagcgag aaggaaatga ttctatcatt
    47041 attgataaag gctattacag aaatgtgact agaaagattg agtgttacta taaagcacct
    47101 tcaattgatg tggtgcagga gtgggaagat cgaatcactg aatggttaga tatgtcgtct
    47161 tatagtgatt ttattcttta ctatgatgaa caatatattt atcaagctgt agtaatagaa
    47221 ggacctgaat ttaaaggaac aagaaaaaca ggaaatattg tcccttttga atttacagtg
    47281 agcattcgac catttaagga aaattacaat ggtagattta ctattcgaca aacagaaact
    47341 tttgaaattt ataacccaga gaagtattct tcaaaaccgc ttattaaatt gagtggttct
    47401 ggagatgctt ctttttatat taataaggac aaatatgatt tgaaatcgtt ggacagagaa
    47461 ttatttatag attctaaatt agaagaggct taccgaaaat tagatggtaa tttagaacat
    47521 caggatcaag tcactttatt tttagatttt ccatttttat atcctggaaa aaatgaaatt
    47581 aaatggacga aaaatattca ttcatttgaa ataatgccta ggtggtggag aaaagtatga
    47641 aaccaagaat atatagtcct actgaaacag atttctcaac gaatggctta ggaattttaa
    47701 aggattgtac aagatgtgaa atatatgaag tagctaatgg aaaatatgaa ttagagttgg
    47761 attatccttt aggaactaga tttgatgaat attttgaaaa tgactatcaa ataaaagcaa
    47821 agccaaacga tcaagaagag tatcatatct tttttattga tgataaagat atagatactt
    47881 ttttaaatac agtaactatt tatgctcaga gtcgtacaaa tcgacttgga agacgggtag
    47941 tcactcttgc ggaagtagac tctaaaactg gtcaagaagc gatatcaatt attgaaacca
    48001 aaatggataa aaaatctgac atacgacttt attctgatat tacggccgtt tctagcacaa
    48061 tctttgaagc gagaaatgtt ttaaattgta ttgctggtga acaaggatca ttgcttcaat
    48121 attggggtgg agaaattaaa cgtgaaccat ttaagctttc tttgttaaag cgaagaggtc
    48181 gcaataatgt tggaacgatt cggtatggaa aagatatgtc tggtttaaag gtcaaattag
    48241 attggacagg tataaaaaca agacttattc catatgctga tcctcaaagt gaggtaggta
    48301 cgactaatcg aatttatggt tcgccagtag atagtgccta tattaataac tatcctgatg
    48361 tgtatacaga gcatgttcag tttacagaag aacaaggagt aaaagacatt aagagcttaa
    48421 ataaaatagc taaaaattac tttaaaacga tcaatcctgg ctgtgataag cctaaagttt
    48481 ctattacggt tgaatttgat aagttgactg atagtgaaga agcgaaagaa tttgcgaaga
    48541 ttagaaatta tggtctgttt gatacattta aaatatatca taaaaaatat aatatttatc
    48601 ttgaatcaaa ggttagtgga ctacaatacg attctttatc tgaaaaaact ttgaaattag
    48661 aagcaggaga cattcaagtt gctttttatc agcaacaagc tgtaactatt caggataaat
    48721 taaaagatta tgcaacgaat aattatatga gtgattttaa tgattatgtt tcttcaatga
    48781 ttacaggtca aggcagtgca ggaggatatg taagtttatg gccaaaagaa aaaccttcca
    48841 acatctttat tatggataat ccagatttag aaaaggcaag agaagtacta agaatgaata
    48901 aaaatgggat tgctttttct aagaaaggat ggcgggggcc ttttacttca gcttggacat
    48961 tagatagtat atttaatgcc aattttatac aaactggatt aatcaaagca gatatctttc
    49021 aaaattcttt taacaagact ggagatgtat tgaaattagt taatggacta ctccaaattt
    49081 ggaacaacaa aaagaaaata atggagttaa ctaaaaaagg aatggaattt tggaattcta
    49141 agggttcaat tggaacgatt ggaacaactg attctgctgg taatcctttt cctggggctt
    49201 ctactccaac ccctattgaa gataattctt tagttattcg tacaaatgga gacggcaaat
    49261 atattttgat ttctcctaaa gtaggaaaag gattagtttt attaggaaat ggtaaagcaa
    49321 tttattttgg agacttagat gtacaaggaa aacttacagt taaaggaaaa gaaataattc
    49381 ctggacaagg tggtggtcca tcgggaggtg gagaatctac tggtgggtat cctagtgaat
    49441 taaaaacaga tgcagaaaag agagcttgga gaat
//
LOCUS       DAFEIE010000013        48462 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFEIE010000013
VERSION     DAFEIE010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.013"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(175..489)
                     /gene="trxA"
                     /locus_tag="LP345_000863"
     CDS             complement(175..489)
                     /gene="trxA"
                     /locus_tag="LP345_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBL1759665.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            complement(576..2936)
                     /locus_tag="LP345_000864"
     CDS             complement(576..2936)
                     /locus_tag="LP345_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBL1759666.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            complement(3051..3599)
                     /locus_tag="LP345_000865"
     CDS             complement(3051..3599)
                     /locus_tag="LP345_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBL1759667.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            complement(3657..4094)
                     /gene="zapA"
                     /locus_tag="LP345_000866"
     CDS             complement(3657..4094)
                     /gene="zapA"
                     /locus_tag="LP345_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBL1759668.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            4296..5213
                     /locus_tag="LP345_000867"
     CDS             4296..5213
                     /locus_tag="LP345_000867"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBL1759669.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            complement(5469..6380)
                     /locus_tag="LP345_000868"
     CDS             complement(5469..6380)
                     /locus_tag="LP345_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL1759670.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(6783..7361)
                     /locus_tag="LP345_000869"
     CDS             complement(6783..7361)
                     /locus_tag="LP345_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1759671.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            complement(7381..8049)
                     /locus_tag="LP345_000870"
     CDS             complement(7381..8049)
                     /locus_tag="LP345_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759672.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            complement(8064..9134)
                     /locus_tag="LP345_000871"
     CDS             complement(8064..9134)
                     /locus_tag="LP345_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759673.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            complement(9305..10669)
                     /locus_tag="LP345_000872"
     CDS             complement(9305..10669)
                     /locus_tag="LP345_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1759674.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            complement(10666..12225)
                     /locus_tag="LP345_000873"
     CDS             complement(10666..12225)
                     /locus_tag="LP345_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759675.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            complement(12281..14761)
                     /locus_tag="LP345_000874"
     CDS             complement(12281..14761)
                     /locus_tag="LP345_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759676.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            complement(14745..15080)
                     /locus_tag="LP345_000875"
     CDS             complement(14745..15080)
                     /locus_tag="LP345_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759677.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(15094..16128)
                     /locus_tag="LP345_000876"
     CDS             complement(15094..16128)
                     /locus_tag="LP345_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL1759678.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(16218..16898)
                     /locus_tag="LP345_000877"
     CDS             complement(16218..16898)
                     /locus_tag="LP345_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL1759679.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPAA"
     gene            complement(17182..18285)
                     /locus_tag="LP345_000878"
     CDS             complement(17182..18285)
                     /locus_tag="LP345_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL1759680.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(18914..19384)
                     /locus_tag="LP345_000879"
     CDS             complement(18914..19384)
                     /locus_tag="LP345_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBL1759681.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            19714..21354
                     /locus_tag="LP345_000880"
     CDS             19714..21354
                     /locus_tag="LP345_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBL1759682.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            21508..22830
                     /locus_tag="LP345_000881"
     CDS             21508..22830
                     /locus_tag="LP345_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBL1759683.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(22898..23329)
                     /locus_tag="LP345_000882"
     CDS             complement(22898..23329)
                     /locus_tag="LP345_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1759684.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEA
                     KKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(23394..24230)
                     /locus_tag="LP345_000883"
     CDS             complement(23394..24230)
                     /locus_tag="LP345_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBL1759685.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(24799..25104)
                     /locus_tag="LP345_000884"
     CDS             complement(24799..25104)
                     /locus_tag="LP345_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBL1759686.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(25129..25560)
                     /gene="ruvX"
                     /locus_tag="LP345_000885"
     CDS             complement(25129..25560)
                     /gene="ruvX"
                     /locus_tag="LP345_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBL1759687.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(25557..25823)
                     /locus_tag="LP345_000886"
     CDS             complement(25557..25823)
                     /locus_tag="LP345_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBL1759688.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(26078..26803)
                     /locus_tag="LP345_000887"
     CDS             complement(26078..26803)
                     /locus_tag="LP345_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBL1759689.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(27164..27234)
                     /locus_tag="LP345_000888"
     tRNA            complement(27164..27234)
                     /locus_tag="LP345_000888"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27200..27202),aa:Gly,seq:ccc)
     gene            27351..28103
                     /locus_tag="LP345_000889"
     CDS             27351..28103
                     /locus_tag="LP345_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL1759690.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            28119..28598
                     /locus_tag="LP345_000890"
     CDS             28119..28598
                     /locus_tag="LP345_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL1759691.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(28849..30429)
                     /locus_tag="LP345_000891"
     CDS             complement(28849..30429)
                     /locus_tag="LP345_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBL1759692.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(30422..31165)
                     /locus_tag="LP345_000892"
     CDS             complement(30422..31165)
                     /locus_tag="LP345_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759693.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(31341..32117)
                     /locus_tag="LP345_000893"
     CDS             complement(31341..32117)
                     /locus_tag="LP345_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1759694.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(32365..33201)
                     /locus_tag="LP345_000894"
     CDS             complement(32365..33201)
                     /locus_tag="LP345_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBL1759695.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(33212..34141)
                     /locus_tag="LP345_000895"
     CDS             complement(33212..34141)
                     /locus_tag="LP345_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBL1759696.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            34333..34686
                     /locus_tag="LP345_000896"
     CDS             34333..34686
                     /locus_tag="LP345_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL1759697.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(34760..35416)
                     /locus_tag="LP345_000897"
     CDS             complement(34760..35416)
                     /locus_tag="LP345_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL1759698.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            35642..37576
                     /locus_tag="LP345_000898"
     CDS             35642..37576
                     /locus_tag="LP345_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1759699.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(37662..38885)
                     /locus_tag="LP345_000899"
     CDS             complement(37662..38885)
                     /locus_tag="LP345_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL1759700.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(38879..40777)
                     /locus_tag="LP345_000900"
     CDS             complement(38879..40777)
                     /locus_tag="LP345_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBL1759701.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(40771..41889)
                     /locus_tag="LP345_000901"
     CDS             complement(40771..41889)
                     /locus_tag="LP345_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL1759702.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(41972..42805)
                     /locus_tag="LP345_000902"
     CDS             complement(41972..42805)
                     /locus_tag="LP345_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1759703.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(42798..43715)
                     /locus_tag="LP345_000903"
     CDS             complement(42798..43715)
                     /locus_tag="LP345_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1759704.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(43942..45066)
                     /locus_tag="LP345_000904"
     CDS             complement(43942..45066)
                     /locus_tag="LP345_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1759705.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            45249..46157
                     /locus_tag="LP345_000905"
     CDS             45249..46157
                     /locus_tag="LP345_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1759706.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            46298..47911
                     /locus_tag="LP345_000906"
     CDS             46298..47911
                     /locus_tag="LP345_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1759707.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        14557 a         9745 c         8295 g        15865 t
ORIGIN      
        1 ggttatcgca acttttataa ctttcgggca cggatctatt tacaacaagg tctgatcttt
       61 gaaaactaaa aaatatgcgg cgcacagaac gcgccgcata tcggactaag ttttattcaa
      121 atttgtcttc accaacacga tttgacgaag agcccttatt tttgctgtaa gtttttataa
      181 atattgatcg atcatttgac gtagttgttc ttttgaatga acaccaacag ctttttctac
      241 tacttgacca tcttttttca acattaatgt tggaatgctc atgataccga attgttgagg
      301 agtttctgga ttttcatcca catccatttt agcaattctg aattcttctt catcatattc
      361 ttgttccaac tgatccaaaa tcggtgcttg catacgacat ggaccacacc aagttgccca
      421 aaaatcaatc aatacaagtc ctttatctgt ttcttcatta aatgtcttat ctgtaattac
      481 ttgtgacata tcaaagacct ccatttttaa aatctatgat tagtatagca tttctatact
      541 tggatagcga accatctgct tacctttagt aagctttact taaatttaac aattgtcgca
      601 ccatttccgc cttggtttgc cggtgcaaac tcaaagcttt tgacgctccg atggttttta
      661 agataatcag taattccctt gcgaagtgcg cctgttcctt ttccgtggac aatagtcact
      721 tgaggataac cagctagaat ggcagaatcc aaatattgat ctacctcact tagcgcttct
      781 tcgtatcgtt ttcctcgaag gtccaattga ttcggcacgt gactactaga ttcagatcgt
      841 acagcatgga taactcgttg tgtcggctct ttttgaggag caacaggcgt cagctcgtct
      901 tcggacacat tcatttttaa tataccgatt tctacttgcc actgattccc gtttttacgt
      961 aaaagcgtcc ctctttggcc gtaagtcgta accaacactt cgtctcccgg tttcaacgtt
     1021 ttttgttctt tcgccttctt caatacttta tttttcttca aagtttcttc ttgatgtaga
     1081 tttgctaatt gggtctttgc atcgatcaac tgatgctctt tcacatttcc ttgcccaatc
     1141 tgctgttgca ttttacgaat atcagcaatg attttttctg ctttttcttc cgcctctgac
     1201 acgacttcgt ttgctttttt ctttgctttt tccatttctt tttcacgttc ttcaaagaaa
     1261 tagctgtaag cttctttcaa atcatcgtga agttcttgtg cctcagaaac aaaatgacgc
     1321 atttccagat attcggtctc tgccattttc cggcgattct ctaaatctgt gatcatttcg
     1381 tttaaatctt ggctctcatc attcatcaac tgcttcgctt catcaataac ttctgtatca
     1441 agacctaatc ggctagagat ttcaaacgca ttgcttcgtc caggaacgcc aatcagcaaa
     1501 cgatacgttg gacttagtgt atccacatcg aactccatgc tggcattaat cgtatttgcc
     1561 cgattgtatc cataaacttt caattcagga taatgcgttg ttgccatcac ataagcagac
     1621 tttttaccaa gatcatctaa gattgcgatt gctagagcag caccttcttg cggatctgtt
     1681 cctgcaccga gctcgtcaaa taataccaga cttttttcat tgacttttga taaaatatct
     1741 acagtgttcg tcatatgaga agaaaaggtc gatagacttt gctcaatcga ctgttcgtct
     1801 cctatatccg caaatacttc ctcaaaaata ccgatttgac tttcttcacc tgcaggaatc
     1861 ggtaatcctg cttgccccat cagttgtaac agacctaaag tcttcaacgt gatcgttttc
     1921 ccacctgtgt taggtcctgt aatgacgatg gcttgatagt cttttccgat tgtgatgtca
     1981 ttagaaacta ctttttcctg atcgatcagt ggatgtcttg cttgtttcaa gacgacatga
     2041 ttgtcttcac tgattcccgg cacgatggct tttacttctt taccaaatcg tgcttttgca
     2101 ttcatcagat ccattttacc aatcacataa gcattgtgga tgatttcttg acgatgggga
     2161 acaagttcag cagaaagttc acttaaaata cgttgaatct catttcgttc agcgatttgg
     2221 tattgacgca aacgattatt caaatccacc acttgttttg gttcaataaa taaagtctgt
     2281 cctgaagcac tttgatcgtg gactacaccg ccaaatacac cgcggtattc ttgtttgact
     2341 gggataacgt agcggtcatt tcgcatggtg atgatcgcat cacttaaata ctttgcattt
     2401 ttcccacgga cgatcccatc taactgttca cgaacagctt gttcacttcg ccgaatgttc
     2461 tgtcttatgc tctttaactc aggagaagcg tcatcagtca cgcgtccgtc ttcatcgatt
     2521 gcttccttta aacggcggct caaaacaggg atcgtgacta actgatctgc ccacatatac
     2581 aaacgtgcaa attcgatttc actgtcagaa agatcatcaa tgaaacgatt caattcgctt
     2641 gtcgtagaca atactctgga aacttgtgca agctccactc cattcaagtc tgctccgatc
     2701 tcgatccgtt tcatatgggg acggatattt tcaagtttag gtatagggat cccgcctcgc
     2761 agacgttgca ctttcaatcc atcctcagtt tcttgaagcc agtttgtgat cgtttgtttc
     2821 tcactcactg gtaccaattc tgccagttct tcttttcctt gtgcagtcac tacaaattgt
     2881 ctgaccatct gtttgacttt ttcaaattcc aatgtttcaa ggattcggtt attcatttta
     2941 tcaccttatc tttcactatg aaaaaagagc tgtgccggac atacgctacg cagccttctt
     3001 aaataaacta ctctgtacaa aaaacgaaat attttccagc actattttcc ttaattcaaa
     3061 atattcgtta cccaaagctc atacatcttg ttggtaagaa atggcgttct ctcaacgata
     3121 aaacgagcga aactatgctc gccgaattga ttttggacca catctaatgg aacaaaggca
     3181 agtaactgca aaatcaaaaa tatagtaacg taagccatga ttagtgacag gatgcctcct
     3241 gcaatccagt ctacctgtct caagatcggc acatacgtca atccatggac aaaaaccccc
     3301 acaaatcggg taagcagcca gccaattagc aaaataatca gaaaagcagt tcctgcataa
     3361 aaagcttcat ctaggtgaaa agcaaatacc tgatcaaaaa atgctaactt tgatgttggg
     3421 gtgacagctg ggtatggaat gtataattcc aaatgacttg ctaatggttt gtaaaaatgc
     3481 tgggcagcaa taaatgacaa tacatatcca atcgcgaata tgatttgcaa agcaaacccg
     3541 cgacgtgctc cagaaaaaaa cgcaattagc aataaaaata aaatcagcaa actcagcatg
     3601 ctacgttcct ttctcttcta acttttttaa atttttctta ttttgataaa aggatcttaa
     3661 ttagaagatt tttgtttaat ttgtcctttt cgtttctcgt ttaaaatctg ttgtgcttcc
     3721 acatgatttt taatggtatg atctgcttga ccattttctt tcaatacttc ccgagcttcg
     3781 ttctcgattg cttcaatgcg tttcacacga ttttcaagct ctgtaaattt gatcattttt
     3841 ttctttaatt ctgctgtttc ttcttccagc tccaagattc tttcttgttt cttcaattga
     3901 tccgaaagcg cattgacagc catcaagatt gctgcttgtt cattatccat ttgtggtgat
     3961 aattgtttca attctgctaa ctgttcattg atcagcttcg ttacgatatc catatgatgc
     4021 ttggtttccc gtccgataat agtatatgtt tggttggcaa tcactgcttt gtagcgtgtt
     4081 ttttcgtgcg ccatacgaat catttcctcc tatttgatga aagttttatt tagtgtacca
     4141 tgaagttggt tctttcaccg ttctccacaa atatttttca catacttaac tattatatga
     4201 taaactttaa aaaaatgcta tgtctcgcaa tctcttagaa aacgaaaagt cgtgagttgc
     4261 ggtatagttt tatgtataaa aacgaggaga attttatgag caacgtcatt atcaaagcaa
     4321 caaacgacca acttagtcaa atgaaagcat actatcgctc ttatttgtta aataaacaga
     4381 ttccttatac tagctttgct gcaaaaaaag acgggacgac cattaccgct tatacatccg
     4441 gaaaagtgat gtttcaaggt acgaatgcag caatagaagc tgataaatgg ggggaggcac
     4501 aggataaaca agccaagcca gcaaaaacag cctcttcttt gccaaaaaat atcagtcaat
     4561 tatccgtttt aggtagtgat gaggtcggaa atggcagcta ttttggtccg ctaacagtat
     4621 gtgctgctta tgtgaaacgt gatcagcttg cagaattacg taaacttggt gttagagatt
     4681 caaaagagtt aaaagatagc caaatcatcc agcttgctga catcttaaaa aaaaccatcc
     4741 cctataaact gcttgtctta tctccagaaa aatacaatga gatccaacca aaatacaatg
     4801 ccgttcggat gaaagtcgct ttgcacaatc aagcgatcca tttgctgcta aaaaaaatcg
     4861 agccagaaaa accagaagcg attttgatcg atcagtttac gccggaagca aattttaaaa
     4921 aatatgcgcg tttagaaaaa aatcaattac aagaaaaact gtacttcgtt actaaaggag
     4981 aacaatatca tttagctgtt gctgctgctt ctatcatcag tcgtgccagc tttttggaag
     5041 agttacacaa agcatcagct gaagctggaa tcacccttcc atcaggagct ggaacgaaat
     5101 ctgaccaagt agcggcaaaa ctattggaga aaggcggcat gcctatgctt gaaaaatatg
     5161 ccaaacttca ttttgccaat acagaaaaag ctttgaagct gctaaaaaaa taatggaact
     5221 gtgacaaaag tcatgtcaca gtcccttgtt ccgaataaac ggtgttctca tgccaactcc
     5281 tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgctccttg
     5341 tgacgcggag ttaaacggca ggctcacaac ctcttcctta aacggtgttc aaaagcttgc
     5401 atctgcgata ataagcccgg ccaaacgaaa aatatgagga gctatttttg tttggctggg
     5461 cttatttatt actgaaaata agtggtcaat gcttgtgtca aacttgcagc aatctgctgc
     5521 tgataactgt ctgttactaa ttcctttaaa tcactatcat tattcatata acccatctcg
     5581 attaaaatag aaggttgaag attttctcga agaacttgat agttcccagt ggagattcct
     5641 cttgaatcca gaggcagatc agtgaaggag tcagcaattg tctgtgctaa tgtttcctct
     5701 tgtccatagt aataatatgt cgtgattcca gttgcttcat tcgcatattc cgtagagtct
     5761 gcgtgtaaac tgataaagac atctgccttt ttttcttcac tgtagtcgca tatatctcca
     5821 agctgtacta attcatctgt agtatgggtc aaataaaccg ttgctccagc atcctctagc
     5881 gcctttttta cttttatggc tgtacttaat gttatatctt tttcttctgt ttgttcatca
     5941 ttgcttaatg ccccagtatc atttccgcca tgcccaggat ctaatacaat cactgcatca
     6001 gatagctctt ccggttttgt ttgtatattc tttgtgactt tggttccatc ttcgagggct
     6061 aaatatccag tatagccatc atttgtcttg atctgataag cattttttgt ttcagaaaga
     6121 aactccgcca gctctccgcc gtttatagtt gcaagtgggg tagttagcga gtcatctgta
     6181 tatagtgtac ggtcattttt tccgattttg attaatgtct cttgttctgt atcatcaaat
     6241 gattcctttg tctttgtaac cgtactgttc gtactgctga ccgtttgtcc aactatcttt
     6301 ttttgaccaa aaacatctat ttgaaaacag ataataatga taatgattgc aaatacaaaa
     6361 gctccaatta tttttttcat tcttgactct cacctcgtag atccagacta agggtcaaaa
     6421 cttaaaatca gcttaagtac gcaaaaaagg ggctgtaaaa gatataaccg tagaaaataa
     6481 cattactgct aaaatgattt ttttcatttt tggcatatcc tgaaatctcc ttttgactat
     6541 tcgtggtgat tcatctaccc aataaatagt ttccttcatt ctacaaacaa ttaatttctt
     6601 cgttattaaa ttaaaacact tcctggaaca ccgacataat aaataaaaat ataccctgat
     6661 aatcatgaga gaataacaaa tttgtattta tgaaaaacta cctatataaa aaaaacaaga
     6721 tataacgatc ttcgtcatat cttgcttctt cacctaacta tttttctccc tatataacag
     6781 ctttacgctt ctcctaatac accattcaaa tataaatcga tcaattgcgc cacatttagc
     6841 ggttcttcca caggtctttt cgaccgagtg atgtaaggtg ctaacactaa gaaaaaatgc
     6901 cttgctgcga tttcttttga aatcccattt cttagcacag attggtttgc tgaaaagatt
     6961 tcttcaaaag gttcacgata atttttcttc catagaaaga aaagatgatc tcttgtttcc
     7021 tttgaaagat tgctttcaag atcgtgaagc atcagaaaca aatcgaccag atgtgtctca
     7081 atcaaaaact gcgccatttt tgtcaaggtt acttgaaatc ccgtttcgct tgtttgaacg
     7141 atttctctca aagcttttcc aacatctttt aagtggtttt ctaaaactgc cgtatatagt
     7201 ttttctttat caccgaaata atgatagaga ttgggttggg tgatcccaac tttttgtgcg
     7261 atctctcttg ttgaagtgcc gagatatccc ttggacataa acaagtcagt cgcttctttc
     7321 aaaatttttt gctgtgtatc tttgttgtat cgatggacca tttttccacc tgctttttgg
     7381 ttattctttt tctttcaata caccatcttc catcataaat attctatcgc atttgtcaat
     7441 cagccgtgta tcgtgagtaa ccatgatcgt tgctttattt ttgtcttttg attcttttgc
     7501 caagatatcg actacttctc gtgccttttc tgaatccaaa ctagcagttg gttcatctgc
     7561 tagaataatg gacggatcat tgtacaatgc acgagcgatt gcgacccttt gccgttctcc
     7621 accagatagt tcttctggat acttgttgat caacttatcc acgccaagct gctcaaataa
     7681 ttcttttgct tctttttgac gatgttcatg tttgatctta tctactaata ataactgctt
     7741 ttttactgtc agaaaaggaa ccagattgga agcttgcaaa ataaagccaa tttctttaaa
     7801 acgtagttta acgcgttcac tttctttttg attactgaat tcttgatcat tgataaatac
     7861 agagccactg ctaggcgtct gcaatccgcc tgccaaagtc aaaaaagtac ttttacctga
     7921 accagaagga ccgatgattg caacaaattc ccctttatcg atactcatgg ttgtttcttt
     7981 caatgcttta actacttggt cgccatcttg gaaacttttt tctacttctt taaattctat
     8041 tgctttcatg ctcttcctcc ttcttatcca attgccttca acggatcgat ttttacgatt
     8101 gtccgaacag aaaatagtgc gcctaacaca gctactacca gcatcaacaa gctaatgacg
     8161 ccaaaaaaca gccaattgct ttggaatgga accgcatcag gtagaacaag ggatgttccc
     8221 actgttccta atagaccaag aagaatacca acaaatgata aaatgaatgt ttgtgccact
     8281 acagaacgcg caataaatcc tcctgtgatc ccttgtgctt tcattacacc aaagatatta
     8341 atcttttgca tcgtcagtac ataaatgaaa atcccgatca caatagccgc aataacgatc
     8401 aaaaatccga tcataaatcc aaaagtcaat acttgcgcat tatatccagg taattcattg
     8461 atgaatttag aaattttgat ctgttctaaa tcttcaggta aattactgat tttacctctg
     8521 acaactattg cgttaatccg tgcattttca cttgtatctt ctttttcgaa gcggatctct
     8581 tggtaagcat tgatggttgt atagagaact ggtgagacat tgaatttggc atgatccgta
     8641 aagccagtta gtttaaacgt cttgtcacta ccagataact taactgtatc tcctacggct
     8701 agaccatatt cttctttcaa actaatatcg cctactgcct catcatcgtt atcaaaagct
     8761 tttccttcaa caagattggg catgatgaat tgatttttat cgataccgaa gaagctaaca
     8821 ttgatttttc cttcttctgt actgtcttta ctagtcacga ctccaggtgt ctgggcaaga
     8881 tacgccactt tcccaccttc gacttcttct gctatcttct tagtaatcat ggacatccct
     8941 agatttgaat ttgcatcttt cgaaagcaca atcgaatctg cctcccactt gtcgactgct
     9001 gttcgattat cttgagctaa gccataagct aacccagtca aaaaaaatac caggtaggcg
     9061 atcaaaaaca tcacccctgc aactaacgca taacgtaact ttgaatgcat aatttcattt
     9121 aatgctaaaa acatttaact cctcctcctg aaataatcat tttatacaac aattttatca
     9181 cttgataaat ttttggcgaa tattatgctc aaaaaattct tccgctattt cattatatga
     9241 attttttatt ctcgattgat taatatttat tatatcccca cacaataaaa gaccgtgata
     9301 tttctcacag tcttttatct actctattgc tatttgctct cttagctagt actttaaaag
     9361 ctaactcatt gaggtagtga aaacgagagg tgtgttcaga cagaaatcca aaatcctcaa
     9421 ctgctagctg tggaatcgta gttttgtgtt tcacgatatc cgcaagcagg ttcaaatctg
     9481 ataataagaa ttcttggctt atcagctgtc cgccaattat ttctaatgta tccggatggt
     9541 agatcagctt tgcatttact gttttgtttt cttcatcgta ttgtggaaat agatcaaatt
     9601 ctcctgaaca cgaaccggta ttttgttcca agaatggcgc ttcatcttct gtcagcccta
     9661 cagttcctaa aaagtagtct ataatgactg ctgctgttat cttttgtctg aggtcgtaag
     9721 cggttggctg accactcaaa gttagcgcta ctgctcttgc catatgtaca gctcgagtaa
     9781 ctaaaggtaa aaagagatgc cgtttatttt tgtcaaaact gactgggacg atatctccaa
     9841 tcgcatagat gtccggatca cttgtctgca gatattcatt gactatcaca gtctcatcct
     9901 catacaaagc cactttttct tttaacaatg tcgtattagg acgagtttgg gcagaaaaaa
     9961 tgaccatatc tgcctttatt gcttgagata gaagttgtac ggatactact ttctcttctg
    10021 attttttcca atcgatcaag aattcatttg gataaaaatt gatttgctta gtttgcagct
    10081 gattttgaaa actgttgatc atatccttat cgaaatatct tgataaaaca ttcggcatat
    10141 aatcaactag atgaataatg tatcctttat ttctcaaagc atctgctaat tccaatccaa
    10201 tataaccagc accgaagatc actacttctt ttgcttcttt taaagcggca agtacttgct
    10261 tagattgcac tagattttta taggtgtaga cattttcagc ttcaatttgt ttatacaagg
    10321 tgacaggaga ggaacctgtt gctacgatta atttatcata ggttatggtc tcgttttttc
    10381 cttctttgga tgcgaggatg agctgatgtt tgtctggatc aagttcagtt actctccatt
    10441 cggtgatcag ttttgcccca ctttcttgaa gagtccgcat gttatgggca acttcagcta
    10501 aactacgtat ctttcctttt aaataaaggt tgattccatt tgaaacatag cctagtccat
    10561 ctttatgatc ttcatcgatc agtaaaactt ctgctttcgg ttgaagtttt cttagattta
    10621 gggcagctgt gatgcctgca tgggaagcac caatgatcac gattttcatg ttttattcat
    10681 ccttaaattc aatttttcta aataacattc ttttaaaaat tggttcaaat aggggaaatc
    10741 ataattatat tcgttgctag tgaatacaaa aactttagcg gacttctgtg acgggtactc
    10801 tttcaattgg ctagtcaaaa tgatatcata ctgcttttct ttctcgtatt cgactaaatc
    10861 atatttgatc gtattcagca attgttcctg gatgatttct ttcacgatat ccgccattag
    10921 cctttcataa ggaagatcat aagcaatttg cagacgtaat tctaactgct tgatcagcgt
    10981 ccgcaaaata gatgcatagc gagcaaataa ttcaaagcgg gcattttcct cgtctacttc
    11041 agtaaaatca acaatagcaa atgtttgtct gaccaatctt tcacataaaa ccaggaattg
    11101 tttatcttct acttcagtta accgctgttt taatccttct tggccaaaaa tattcatcca
    11161 tcctctaaaa taggcaaaat gagcgtgatt ttgcatcact gtcaacgcaa tcttttgcga
    11221 aatctcttct ggaaaaacat aaaaagagaa atattcttct atcgattgtt taaacgttcg
    11281 attcaattga gctactacgt cgtctttgta tttttcgctt atcaaaaact cctggacatg
    11341 cgagttatgt gtatctaatg taaagttact gatcatgaaa agataaaaaa ccaacgtttc
    11401 attttgattc caaggaaagg catattgaaa gaagtaacgg gtcaaaaatg tatggaggtc
    11461 caataaaaat tgtgtcgttt gaaacaatcc aacaggaaga ttgctataat ctggtttgga
    11521 ttttttcgta cagcgcattc gcttcttcat aatggaaagc catatttcaa atttcaatcg
    11581 tccttcttct gtaatagtaa aactaaactc tttttgcagc agatctaaaa aagtgtttcc
    11641 tgataaatca ctgtattctt ttttgttttc aagataagga cgtccaaacc aaaataattg
    11701 gaaataaaaa taacaaattt gactttctgg accggtcagc cgcccgcttt ttattttcag
    11761 atgaaactca tttaaagaat catttaattc cttcactctg cgagacaaag tagccgaact
    11821 gatattaagt tccatgacaa gtttctgccg atcaaatgag ccattttcca acagataaag
    11881 aagtatctga tattttgtag aatagcgcaa gtagcaatga taataaacat cgactgctgc
    11941 tatatttcca tgtctgatta ataaaatatt cccttcttgg ataacaattt ccaattgttt
    12001 gatattttcc aagttagctt gtaaataaaa cagatcttct ttcaaggtag cccgatcaac
    12061 tgataagcgg gtaagtacgt tattaacgga aatctctcct ttttcctcta ataaaagttg
    12121 gaaaagtttg atttgccgtt gttcattttt ttcaagcaaa ctgaaaagtt ccaagtccac
    12181 tcctccaagc atttctgatt ttaacagcag aagtttcctt ctcatccttg aaaaagagga
    12241 tctgtgacag ttatcacaga tccatacaaa ttctaatcac ttagctggtt ggcccagctg
    12301 tcagttccca tgtgaccatg ccttgatacg ttgcgccagg ttgagcattc gtactgctat
    12361 ttacctctaa gagtaaacca tcggtatcgg gaaagtcaac gagaacctct cctttagctg
    12421 ttccatcact ctcataaatc aacgtgtttt gaccttgctg aatcaattgt tttgatccag
    12481 aatgattgaa gtataatttt gttccgctta attcttgacc ttgatcattc ttaaataaag
    12541 aagtcaatgt ccctgtcagt tgccaaggag acgtgcttgg aagccgagta tcccgcacat
    12601 caaaagaaaa atcgcctttt gcttcataat aacttgtctt caacggtttg gggagatcgt
    12661 taccaaatgt aaaatcatct ggtacattaa ctaatgttaa ttcttgtttg gggacaagaa
    12721 ttgttttagc agatgtttgg acaactgggt taggaagctt agcaccatct gctaatgtaa
    12781 tattgctgga aagtacagct gcctttgtca gtatgctgac ggattgtaca gaagtatcta
    12841 cagtatttaa ttgatagttg taagtaagat gaatggtatc tcctattttg ctcaatagat
    12901 ctgctgggac agaaactcct tgttgaatgc cggtatctgc gatagttgta ccatttaatt
    12961 ttaaggaacc attgatataa gtagtatttt caggaagtga gatcgtgatt tttttgtcgg
    13021 ttatcgcatc cccagatttt gttaacgtga atgtcacatt ttcttgaatc gtatctcctg
    13081 atagagcaga caggggatct cctgtctcag gttgtctgct aaggtttttt agctgactat
    13141 ctgcactcac agatggaaaa ttagccactg ttatttgagg aagagtggtg attccagctt
    13201 gttcagactg ccatttgtac gcaaaagacg gatacatgtt agtaagtaca tcgtccacca
    13261 agcgataatc aaaataatat tgccctgaag ccaatgcagg tagtgtagaa gtagctgtat
    13321 ttacaccccc gttatttgat tggatcgttt ggaaaagttg atctgtccat cctgtcgcta
    13381 atttttgggt tcctttcgaa taaagcctgt aatggatcga accctttttt agttcagttg
    13441 ctgaccaatt ggccgtgact tggtacgatg cagaagaaag gagctttccc cactgactat
    13501 cggctgttaa gtttgttggt aaaaccgttc cgtctagctt gtactgctcc aataccttta
    13561 aagcaacagg agaaagcaat ccgccttgcg catctttccc actgtacacg atattggctg
    13621 tctgattcaa tccacttgtg cttgctggag tatgagtcag tattgctcct tgtgtaacgt
    13681 tttttcctgt aaaatagttg actacgcgat caaagcgact aaatggcaac tgatcaaaac
    13741 gtccttcagt cagccccatc gtcaatgtcc gactattggt agagcctgga aggttctggt
    13801 tatttccatc cacgtattct gtggtatcag caaatgtatt atattttcct gttgaatcac
    13861 ttgttgagat gtaactattc cacgtattta tctctgcact tgcagaaaat gcatatgctc
    13921 ctggattcaa gtttccgcca gttaatttag gataaaatct acctgcagct ggagctaaaa
    13981 tcgaattgaa catacgatct tggataatat tattcgaatc ataaaaatca acagaaaaaa
    14041 cggccttttt agacatagaa ggttgtaatt tacccttggt caaaattttg tttggactcg
    14101 tatcatattt atctccgttt tctgtcatct tcgcgacatt agctgtaaca tcaaattgaa
    14161 gcgggatatc gtccacgttg aattcgcctc gcgtaataat agcaataata tctgccaata
    14221 gagtatttgt atcccacgac cccatcccaa aacgcaaggt atggcttcct gctgataata
    14281 aactaccgct agtaaccttg atgggggcac cggcaatata caagtaggcg ttgttccagt
    14341 caattgcttt taatacatca ctgcttgata catgttccgg caaattgatg atcgccacaa
    14401 atgcaaatcc ttgtgcagtg atattcacca aatcaagtac atttgttagt ttcacatggc
    14461 tttcccaatg aaaacggacc gtgccacctt tccaaggatc atttgaacca tcgttcaaat
    14521 aagtagcagt caatttaggc aattggttag ccccagttag ttggacaagc ttcccgccat
    14581 tgactgcact acgtccacca tttggaggta cgatattttc atacgtgtat ggatcataag
    14641 aaatggcagg aggcgttgct ccaacagctt ctgccgaagg tgaaaagata aatatactta
    14701 aaacaaaaag cgaagtaaaa aagaaggagc gaaaaaatga aaatttattt tgtagcaaca
    14761 tgttcatcct ccttttcctt tcttctccat aacaacaacc acgcaagaag ccataattct
    14821 ataccaatga tcaaataaag aaaacggatc ttttcttcat tcgtctccgg gaatacgcca
    14881 tgttgattag attctttata aatcggtagc tgtgtctgct gttttgatgc gccattgact
    14941 gaaccacttg gatgcggaac tggacttaga tcataaaatg taatcgtacc tgaacttttg
    15001 gtatctgctt ggactggctc ttgccagctg aagaacagca aacttgcaat aatccctccc
    15061 aataagatcg atgttttcaa cgaaatcacc tcatcatgtt gtttctcctt ttttcttttt
    15121 cttgtggacc cacaaaaaca gcaaaatcaa ccataacact agaactgcag caaccaatcc
    15181 tgcataaagc catgggaaag attgttcttg tactgcaaaa acggaatttt catttacttt
    15241 ttgtgctttt tcttttttga tcgtaaagtt ttgtgtaaat cgccattcat tactgtcgcc
    15301 tgattttgct atgatttctg cgcggtaatc gccggctttt gctttatcac cagctaaatc
    15361 aagattcaag tgaaaattcg aatttggtgc aactaaaaat tcattagacg tattttcaat
    15421 ataaagctga ttttcataaa agatcttgct cgtaaatatc aaattgctga taatcctagg
    15481 ctgaggattt tggaaacgaa gctgaacagt tggctttgcg ttgacctcgt ccaaatctcc
    15541 tgataaaagt ttcagatccg gttctatcgt ctcttgactt tcttgtaaaa cgactgcgag
    15601 attataagca atacgatttt tgatttgtgc tccttctgta gcattttctg tttcagcttc
    15661 ttctttaggt gaaacatgaa tacccgctaa tacacgtccc ttaaagcttt ttgctgggat
    15721 tttcacttct ataggtatag ttgtttctgc atgtgctgat acattgattt cctttttcgc
    15781 aatgagcaaa acgtcacgga catcaaacgg caatgtctca tctaacgttg ggtttttttg
    15841 actataatcg atcgttccac catcactcgt taccgccgga ttgacagaga cctcaaatgt
    15901 tcgttcttca tctgaagaat tgctgataat tacttctagt gtctgatttt gttccggtgc
    15961 cactaataaa tcaaaataac cgattgcttt atctatttgg ttctctggaa ataccggttt
    16021 gattccaaag tctcctgctg aatcctttgc ttggctgatt gacggaaaaa tgaaaaatag
    16081 acttaaaata gaaaaaaacg aaacaaacag tcgtttactt tgattcattg tccaccacat
    16141 cctttcaaca acaactgcgg taaaaaatcc ttcacctata gtattttcac cgcagtttgt
    16201 tgaatttatt tcatactcta tgctgctggg ccagccacga ggttccaagt caaatcagcc
    16261 gtgaatgttc cagctgctgc tttcggcact ttcagtgtga tatttgctgg atcataaaca
    16321 gaaagccatg ttcccagacc ttgatctttt gctgctgtaa atattggtgt cgctgcactt
    16381 gctttactca acccagttac agtttgacta gttggtccag tggattcgtt atctgacgta
    16441 cttttaacag tggatgttcc aaaatctaat tcagcgcctt gcaaaacttg tgaaccgttt
    16501 acaaaatctg aaaccgaaac tgtcacgttc cacccttgtg cttggccatc tgcacctaca
    16561 cctcgacgat ctgatacttg gagataaggt gtatcgtttt ttgaagcgtc tacttgatac
    16621 gtttttgttc cgctttcaat ctcgtgtgta ccaaatggca attcaggaac tacatccaat
    16681 gttaaagaac ctgtctggcc agttgctgga ttttccggat ctgctggctc tactggtttt
    16741 gaaggatcag tagggttaag aggctcaacg gtatttgttg gttcagtaaa ggtaatatct
    16801 ccttttgaag tcgcttgacc ctcagcaaaa gctggtgttg ccaagccgcc tagaagaagt
    16861 gttgaaagta ataatgtccc aatcatgttc tttttcataa taaatcactc ctttttctta
    16921 gtgacctaag tatagtagag acagtatgca aaaaatcctc atgaattcat ccgcttactt
    16981 gaaattatga ccctttttgt ataaaagaga aaaaaacaat aaaatcgttt acatgaatat
    17041 tcttcctttt ttattaagta tgaaaaaata tttcaatttt attttttcgt ttcaaattat
    17101 tctattagtg acatccttga actataaaaa taggagtacg gcatcatctg ccgcactcct
    17161 atttttttcg tcatttattt cttaaataaa acgattctca cgcaatttta tttttttgat
    17221 atcttctact gtttgtgttc cagctaattg catgaccatt tccaattctg ttttaaagaa
    17281 atcaaacact tgatggactc ctgtacttcc tcctaaagac aatccataaa taacgggtct
    17341 gccaatagca acaagatcgg cacctgatgc gattgctttg aaaacatgtt gtccacgtcg
    17401 tacaccgctg tcaaacacga ttggtacacg tttatctact gcttctgcca catattgcaa
    17461 cgaatcaaac gcagcaggcc ccccatctaa ttgacggcca ccatggttag atacccaaat
    17521 tccaccagca ccagattcta atgatcgata gacatcttct tctgattgaa cacctttcac
    17581 gtagactggc aaatcagaat gagcagcgat aaattctaca tcttttggac taagtttttg
    17641 tttggaagat ttatatacag catccatcgt ttggcctact cctgattgat aagcctgaac
    17701 gattggcatt ggcagcggga aggtaaaccc gtttctgcgg tctgtttcac ggtttccgcc
    17761 aactgttgca tccgctgtca atacgattgc ttttgctcca ttacgcttgg ccacttcaag
    17821 aatatccaaa ttgattccat tatctttgct catataaaat tgaaaccatt gcggtgcttt
    17881 ctccccgcct gcttctctta tctcttctaa agtacaagaa gcgtaagaac ttgctgtata
    17941 gatcgtccca aaatctgcta caccttttgc agaagctttc tccgccttca catgagctaa
    18001 tccatgagca gcaactggtg ccatgatgat tggtgcagtc agcatttctt cgtcaaaatg
    18061 tgtagttgta tcgggtaatt ctacatctct taatacatga ggaataatca aacgatgatt
    18121 gaatgcccgt tcattttctt gataagtaaa taagtcgcca gcaccactgc tgatgtaacc
    18181 ataaccacca gctggaatca cttgtgaagc cgcgatttct aaatcttcca tattgataaa
    18241 atctactatt ccttcatttg tacctgcttg atatgttttt tccatctcaa tgccttctct
    18301 ctataaaatt tgaatgatga acaatatgat agcgtttaca ctttttatat tactcttcga
    18361 cattgataca ggcaaataat ctgtttacat ttcagccatt ccagatgtca ctactctgga
    18421 agaaatgatt gtaataaaaa tagataaaaa accgatggga ctttgacaaa agtagtgtca
    18481 aagtcccttt ttttgaataa acggtgttca aaagccattt tctcggtatt aagtcaaatt
    18541 tatgcaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga aactaagcga
    18601 ctttttcaca acctctcgat aaaacggtgt tcaatcagct gaccctcggt attagctcaa
    18661 aaaatggcaa aatatgagga actattttgc catttgtctc tctaatactc aggtcagaac
    18721 gttgacttca cagtctcttc cttaaacggt gttcaaaaac ttgcatctgc ggtaataagc
    18781 ccaaccaaac gaaaaatagg aggagctatt tttgtttggc tgttcttatt acttgatgca
    18841 gggcaggttt ttcacgacct ctgattcacg gtgtttcttt ttcatcaaca tttttacgaa
    18901 atactgtgga agactattga aataagtgtg gattgtttct ttgtgtttca atcgtttctt
    18961 gccattcttc atttaatttt ggattaccgt tttcttcctt gaactcataa ggtcctaatt
    19021 caaaaatccc agacagtatt tgattcacga tttcatatag ttcagtgtga tcagacacat
    19081 gattcttgaa gatcatctca ttatcaccac gtttgaacct cacattcggg ctctcatgat
    19141 gaacctctat gcatttttct ccttttttta actgacggac ttctgaaaac atctcataaa
    19201 tatcttctcc agtaaaacct tcagcaagcg ccagactgtc cacaagaccg cctactgtca
    19261 gttcagagat tattgcttga ttggaatcta attttaatgt atagcttgtc gcttctacta
    19321 cgccacatgc attgcaaccg ccttctgata gttcgctttt tctaatcaat tgaacttctt
    19381 tcattttctc ttcctcctct taattttcta cttatgtatt tttatcacct gacataggtg
    19441 actcctatca acgctatcat gtgctttttt cctcagaaat cctatttatc cattccatct
    19501 atcccttatt cttctacttt tctttctcta gcatataaga gatacgcata gtattcaagc
    19561 aaggattgtc gatataaaaa gaacaaatac tgctattttg atttcttttg gctatattac
    19621 atataaataa aatttatcat acctgctctt tttgactata tcatcatctg acttctatac
    19681 ttcgtttgta ttaaaactta ggaggaatca ttcatgctta cagggttaaa cttattaaat
    19741 aatccttttc taaataaagg aacagctttt acaaaagaag aacgggcaaa atatggaatc
    19801 actggtatgc ttccaagtac tgtccaaaca ctggaacaac aatctgttca agcttatggt
    19861 caatacttaa gcaaacaaac agatttggaa aaacgtatct tcttaatgaa tctattcaat
    19921 acgaatcgga cattgtttta taaattgatg ggcgaacatt tagttgaatt catgcctgtc
    19981 gtttatgatc ctgtcgttgc ggattcaatc gaacaataca acgaaatttt cttgaaaccg
    20041 caagatgctg catttctttc aatcgacgaa ccagaaaaca tcaaagcaag tttgaagaac
    20101 gcggcagatg gacgagacat tcgtttgatt gttgtgactg atgcagaagg aatcttaggt
    20161 atgggcgact ggggtgtgaa cggtgttgac atcgctatcg gcaaattgat ggtctatact
    20221 gctgctgctg gtattaatcc agcacaagtt ttgcctgtat cgatcgacgc tggtactaat
    20281 aatgaagaat tattgaataa tcccttatac ttaggcaatc gtcatgctcg tgtagaaggc
    20341 gaaacttact atgaattcat cgatcaattc gttcaatcag ctaccgaatt attcccagaa
    20401 ttgttattgc attgggaaga ttttggacga ggaaatgctg cagcgatctt agaaaaatac
    20461 gaagatcaaa tcactacttt caacgacgat atccaaggta caggaattgt tgtcctagca
    20521 ggtgtattag gcggattgaa tatatccggt gaacaattga aagatcaaat aattttgaca
    20581 tttggtgctg gtactgctgg tgtgggtatc gcaaacatcc ttttagatga gatgatccgt
    20641 caaggtgtac ctgaagaaga agcacgccaa catttctatc aagtagataa acaaggttta
    20701 ttgtttgaag atacagaagg attgactcct ggtcaaatcc cattcgctcg caaacgctca
    20761 gatttcacta atgctgatga attgacaaac ttagaagcag ttgtaaaagc gatccatccg
    20821 acaatcatga ttggtacttc tacccaacct ggagcattca ctgaagaaat cgtgaaagaa
    20881 atggctgctc atacaccacg tccgatcatc atgcctttgt ctaatccaac aaaattggca
    20941 gaagcaaaag caaaagattt aatagaatgg acggacggaa aagcattagt tggaacaggt
    21001 atccctgctg ctgatgttga atataatggt gtaacttacc aaatcggtca agcaaataat
    21061 gctttgatgt acccaggttt aggacttggt ttgattgctt caacagctac acgagtaaat
    21121 gctgaaatca tttctcaagc tagtcgagca ttaggcggaa tcgttgatgt aacaaaacca
    21181 ggagcagcta tcttgcctcc agtagcaaaa atcactgaat tttctcaaac gattgctgaa
    21241 actgtcgcaa aatcagttgt cgcacaaaac ttgaatcgtg aagaaatcac ggatatcaaa
    21301 gaagcagttg aatctgctaa atgggttcct gaatataaat ctttagaaga ttaagatcgt
    21361 tatagtaaaa gaacatacag aaactttgta tgacgtctaa aaagaaaaaa gcgactgcgg
    21421 caaaacagcg gccagccaac tcctgctctt ttgtcgcttt tctttggctt ttttcatatg
    21481 atacagaata agaaaggatc tgtaaaaatg gcacaaaaaa caacaactgc aactgcagtt
    21541 gaggaaaaga aaaaagaagg tttttggtcc acaaaaatca ccggcgtaag tttgccactt
    21601 tatttgatca tggtccttgt cctgatcatt gcaatggctt tagggaaatt accgacgaat
    21661 atgattggac caatcgcagt tttggttatt ttcggtaatt tatttcattt tatcgggaca
    21721 aaaatcccta tcgtcaaaag ttatttgggt ggtggttccg tttttgcgat cttcgcttct
    21781 gctgcgattg ctacatttgg gatcttacct gaatatgtag tgaaatccac agaaaacttt
    21841 gtcagcaata tgggcttttt ggacttttat attgctgcct tgattactgg tagcatcctt
    21901 ggtatgaacc gtaatctatt gatgaaagct tctgttcgtt ttattcccgt tgcacttatt
    21961 tcaatggtcg tctccttttt tgccgtagga ctcgtgggca tgcttatcgg aaatggtttt
    22021 gcaaattccg ttttatacat ctcattacct gcgatggctg gtggtgttgg agccggagcc
    22081 gttcctttat caacgattta tgcaaatgtt ttaggtacgg atgcttcttc tatcatttcc
    22141 cgcctgattc ctgcgacagc aatgacaaat gtcttagcta tcatcggtgc agcattagtt
    22201 gctcgtgctg gacaatcaat gccaaaattc aacggcaatg gtaaattaat ggaaaaaggc
    22261 gatcttggcg atggaaaacc tcgaactgtg aaaccttcca ttccacagtt aggtgttggt
    22321 ttgatggtat cattgacttt cttcatctta ggacaaattg gtaactattt tgttcctaaa
    22381 gtccatgctt acgcatttat gattattatc gttgtcatct gtaaaatcgc caacctatta
    22441 ccagagtatt atgaagatgc agctatcatg ttcaataact tgattgtcaa aaacttgaca
    22501 gcagctgttc ttgccggtat cggtattgcg ttgctgaatc tgaatgtatt agcttctgct
    22561 ttgacatggc aatttgttgt cttatgtctg acaagtgtta tcgcgatttc agttgtttca
    22621 ggatttgtcg gtcgtttgtt tggtttatat ccaattgaat caactattac tgctggctta
    22681 tgcaacaact cgatgggcgg aacaggaaat gtagccgtct tatctgcagc taatcggatg
    22741 gaacttattg cttttgctca aatgggcaat cgacttggtg gtgccatcgt tttgatcatc
    22801 tctggtttct tgatgcaatt actttcttag tcaaaaaaac aaaaatacct gatcatcaag
    22861 tatcggcttg gtgatcgggt atttttttga taaagattta caggattttc aaaaatcttt
    22921 tttgcatttt atcggaatga taaccgatgt gttcataaaa ttggtgtgct tctactctgt
    22981 attctgcaga attaagcctt attgtcgtta ttcctcgttt tttcgcttct tctacgccag
    23041 tcatcaaagc ctttccgatg cctctttttt cagcatattt agacacagca agtgccataa
    23101 tattgaacat tggatcgcta aaaatcgatt cataggactc cgcttgtaca tagccagctg
    23161 cttttttaga agtaggatct tcataaacca agaaaaaatt tttctctggc tccttcagca
    23221 gtttcttcat ttgtctcacc gtaacggtta atggtatatc ataccctaat tgatccgcat
    23281 tgatttcacg tagtgcttct gcatcttcta aacgcatttc ccgtaacatc caaatcacca
    23341 gccaatttct gattttttaa aatgaatttt tttatcatag tatactcttt ttttcattta
    23401 gaacaatatg tttcagtgat tttgacttgc gttagtctag attctcctaa tgtttgtaag
    23461 atgacaaagg cattgtaaca attgaccaaa agaaccacga ggacaattac ttgaaaaata
    23521 aaggtcactt tttttggaga caaaaccctg ctaaatcttg ctccccacaa acctccaata
    23581 acagcagcgg ggataacata aaacaacata gataaatcaa agcgcataaa gctacttgtt
    23641 aaagcaatcg ttaccaattt tgccagttga gaaaagaaaa tcgtagatag agaatatagt
    23701 gttgcttctt ttattggcaa tgcaaacatc agcatcaaca aagaaacatt gactggtcca
    23761 ccaccaatac ctaaaaaact agctaaaaag cccagaaccc ccccacatat aaggtaccaa
    23821 gtccatgacg tcaaatgaaa ttttggctga tgatgcttgg tgtagaagaa cgcaaaaacc
    23881 aaggtcaata ccgtcaaaaa aatttggatc agctgcacat gcttctcgtt ttcaaataac
    23941 tgtaaaaaaa cttcgaatac aatgttgccg actactcctc caacaacagc tccactagat
    24001 acccaaccga caatctgcca attcagtgat ttcccgcttg atacttgtcg cacagtcgaa
    24061 acaatggaca tcgtgaatac cgcaactgtt gagtaaaaag aaatccctgc aacagaatgg
    24121 gcgccgataa gatcaagaat cggtttgatc aacacgcctc cacccatccc ggaaatagcg
    24181 ccaactgtgt tcgccagaac gatcaccaca aaataaatca gaccaatcat cttgtatttc
    24241 ctttctcttg tttatatctt ttagcgattg ttactctttt cttttattat acagtaaaag
    24301 aaacaaacga ggcttcgaaa gcttttctac tttttaagga aatttagtgc taaacgaaaa
    24361 gaggttgtga aaaagctgtc ctgcatcaag taataagaac agccaaacaa aaatagctcc
    24421 tcataatttt cgtttggttg aacttattac cgcagatgca agcttttgaa caccgtttaa
    24481 gaaagaggtc gtgagcctgc cgttcagctc cgagtcacaa ggaacaattt caaaaaacag
    24541 cttctcatgt ttgttgaata ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
    24601 taaggaagag actgtgaagt caacgttttg acctgattat tagagaaaca aatggcaaaa
    24661 tagttcttca tatttcgccg tttttcgagc gaatgccgag gggcagctga ttgaacatcg
    24721 tttatttgga aaaagggatt gtgacaagac gtttgtcaca atcccttttt ttatatctta
    24781 ttaattcatt cttttgttct attcttcttc ttccgccatg aatgtattga atacttcttc
    24841 aatcatgtcc cattctgcgt ctgtttcgat ttgttctaac tcgccttctg ttccatcttc
    24901 gttttcgatg tatgcataag cttgtaattc tacatcttca tcttctgaaa caccagcagg
    24961 atataaaaga acatagttac gtccaaattc ttcttgtccg tcaactgtta gtaggatttc
    25021 atataatgtt tcatttcctt ggtcatccac caatgtgatg tgttcgtgtc cttcatggtc
    25081 gtgggaatgg ttatgttctg tcataagatt acctcttttc ttttattatt aaaataattg
    25141 cttacctgag ccgtctaaat aattttgtaa gatcatcaca gctgctaatt tatcgatgac
    25201 tttttttcgt ttggctcttg aagtatttgc ctgctctact agcatacgtt ctgcctgaac
    25261 agtggttaat cgttcatctt gataatcaac tggcaaggag aatagttctt tgatcttttc
    25321 tccgtatgac atggaagctt ctgcccttgg tccgatggaa ttgttcatat ttttaggtaa
    25381 tccaactaca aaccggtcta cttcatattg tgctactaat tccttcaacc gatcaaagcc
    25441 aaactcttct tctgcttcat tgatccgaat gatctctact ccttgagctg tccagccaaa
    25501 ggggtcactg atagcaacac ctactgtctt agaaccgaca tccaagccca ttactctcat
    25561 aaattcactc catgatttga gaggtagtcc ttgacaatta cttccatgat ctcatcgcgt
    25621 tcgtgacggc gaatcaaatt tcgagcatca cgataacgag gaatgtaggc cgggtctcca
    25681 gaaagcaagt agccgacaat ctgattgatt ggattgtagc ctttttcttc caaagcccga
    25741 taaacaatcg ctaatgtttc gctcacttct tttttgcgac tatcgtcaaa accaaaacgt
    25801 acggtttcat ctgtaaaacc catgattcta cacctctttc ccgcaaggta attccagctt
    25861 accttctaca accttatttt actcgaagaa agggaaaact acaaacaaat attccaaact
    25921 tccgaataaa ttaagaaaca ctatttgtat gtttttttcc ttttttctgt agctttatca
    25981 aaagtactct tttcataaag tatacgctat atttctttga atgtatgttt ttacacaatt
    26041 ttttcataat attcataaaa aattcgaata gctgctacta attttttgtt tttgttgctt
    26101 gtcctgtctc ataattgatc gtgtagccat cttgaacatt gtagataaag acattgaatt
    26161 caattttttt gtcttcaatg ctttctgctt ccaattgcac tcccctggct accagttcat
    26221 tcccctcaaa atgaggagtg acacggtagc gtacatgatg atttgtttct ttgatatatg
    26281 ccgcaatatc attttcgtga gcaagcatgt atggagcatt caacgaacgt gtccctgtca
    26341 tcaagttttt aatgttgtta ttttgaccag tcagctggaa accaattaaa tggctgcgat
    26401 tatataacca ttgcccgtca cttaatttct tttgtttcca acctgtcggg tcaatataca
    26461 aaggctctct cttttcagta gggaacaaat cttttccaag catagcattg gcttgtccta
    26521 ctctgttcaa tttatcaata tttgaatagc tttcccatgt tcctttggaa aggctaagat
    26581 cctcttttgt aaattccggc tgattcccat tgatttctat ttcttgatgt tttccatcat
    26641 attctggcac atccgctact tgagaagctt gtggtgtgga atcaaaaata gttgtaatct
    26701 gctgaaagat atctgaatct ttttgtgtgg tggaaacacc gaatgcccct gcaatcacag
    26761 cagcgacgat ccccacgatc gccttggttg tttttttgct catttcttta ctcctttact
    26821 aacagctccc taaatcttaa catatgttcc cctataaata aatactagaa agaaatagaa
    26881 acagcaaaaa ataaaacctg ttttaagatg gcttaaaaat acaaaaaaga gacggattcc
    26941 tcgtctctaa tcagtcacca ctctatctgt aaggtattta ttattattca aaaattttct
    27001 tcatactcaa gacaatacac tgatttcaca accgcttggt aaacggtgcg caaaagcttg
    27061 catctgcggt aataagtcca tccaagttaa aaacataaga agttgttttt gcttggctgt
    27121 tcttattact tgttgcagag cagctttttc acaacctatt ttaagcgggt gacgggaatc
    27181 gaacccgcga catcagcttg ggaagctggg attttaccac taaactacac ccgcaataca
    27241 aaaacagtat acgcctcttt tattccttcc tcaagttttt ttattcttta cgcttctggt
    27301 atgttttgta gtaaaataaa actaatcaat caattattgg agaagatgct atgacgggaa
    27361 aagaattaga tctgttgctg gacacttgtt tactcgctgg gaaaatcatg atggaaagca
    27421 atgcggagat gtatcgggta gaagatacga tgagtcgaat tgctttagct tctggaaatt
    27481 tccgtttggt cagctatgtc actcaaaccg gtctctttat tggtcttgat cgtacctcga
    27541 ccatccgaat ggaacaaatt accaaccgtt cgattaattt agaaaaagta gtaaaagtaa
    27601 atgatctttc acgtaaatat gttgcttcag agctaacatt agaagaactt tactgcgaac
    27661 tgcaagcaat cgaccgagac cgttctttct ttcctgtctg gttgcaaatc gttagcgcgg
    27721 cagtgatcag tggaacaatt atggtgttat ttggcggaaa gatgaccgat ttacctgtga
    27781 ctttagtcat tggaggattg ggatacgcag cttatctata tagtttgaaa ttttttagaa
    27841 tcaaattttt atcggaattt ttatcttctt tattgattgg catagccgct atctacagcg
    27901 tacgttttgg cttaggaagc aatcaggatc taatcattat cggatgtgtg atgcctttag
    27961 ttcctggagt tcaaattacg aacgctatcc gtgatttgct agctggacat tatgtctcag
    28021 gagtttctcg cggaacagaa gcgatgatga ctgctacgat gatcggtttt gcgattgctt
    28081 ttattttcca gcttttttat taggaaagga acacaagtat ggggacgata tttattcagt
    28141 tttcttttag ttttttagcg actgcggcat ttgccgttat tacaaatgta cctaggcgtt
    28201 cattgatttg ttgtggtctt tctggtgctt ttggctggat gatctactgg atctgtgttc
    28261 aaataggcgg atctgctgct tttggttcat tgcttggttc tttaggagta gcattcatca
    28321 gcgatctttt ctctaaacgt ttgaaaatgc ccgtaacgat tttcaatatt cccgggatgg
    28381 ttcctctagt ccctggtggt ttagcttatc aagcggttcg aaatctcgtt actgaatcct
    28441 atcgagaagc ggctcattat gcggtccaag caattatgat tgctggagca atcgctttag
    28501 gtcttgtatt atcagaagtc tttaaccata acatccgtaa tttcaaagta aagcgtgacg
    28561 caatcatgat gaaacgaaaa aaacggcttt ttaaataaac gaagtgtaac aaagaaaagg
    28621 ttgtgaaaga gacgttcagc cttgagcgat gacaaaatat ctcacaaaca ttgcgacaag
    28681 taaccgcagg agcaataaga agtaattatg agtattaaaa aaagttttgt aaaaatagct
    28741 tctcacattt ttacataaaa ttgacttaat actgagaaac tgacttttga acaccctcta
    28801 tctgtaaaaa aggggctgcg acatgatttt tgtcacggcc cctcttcttt attcaaattt
    28861 tttccaaaac gttcgttgat aataaacgat ccatagagcg gaaagtatta gaactaaacc
    28921 gatcacagga atattcacta accaaaatgg ataaaacaaa gccaacattc cgtataagac
    28981 gataagaata atactgatga tcaatgaacc catcatagtt gcgactaaac ccaaacttcc
    29041 tgaacctctg ttaaataatt ggttaatatt ggtccagttc agcagcagca accgataatc
    29101 tctagcgaaa taacgtagtg acaataagta gcagccgaat aaagaaccaa atagcaagct
    29161 agggataaaa aacaaaggca gctgaaaaga cagtccgctt aataatgcga tcccaccagt
    29221 taaaaaactc tgcaatatcc atccgaatct gaacttttct tttaaatatt ggttcataga
    29281 gattggcaaa gaacggataa acagaaaatt ttcttgatcc aaagaaataa gattgctgat
    29341 aaaagaagtc tgattaactg ttaagaaagc caatgcgatc cctaccagga aaacaacacc
    29401 gattaactta ttatctaaat cagttaattt tatttcgcct cctagggcaa aagcaagaat
    29461 aaaaatgatt ggagttaaca aggaagaaga aagaacttgc ataatcaaat taggttcttt
    29521 tactaattga gcattgtaac taaataaaag ctgatgcaca ttttggttct ttttatgggt
    29581 tctttttatt ttgaactcac tgtttgaatc agtcagttgc tctgtaagct ttggtactat
    29641 cagctgtttt acagcaagga aaaatcccag agccgtgata gctagtattc cccaacccaa
    29701 taaaccttgt tgagaaagtg gctgactggc agcatcatag aatggcaata atatcgaaat
    29761 cggatgccga tctgttaact cattttcaat agtccccgtt tgatgattca tccacatgat
    29821 tccagcaaat gcgatcagca tcgagctgcc aagcaagata ctagaaactg tttttctatg
    29881 ttttttaaac actgctgttc gagccaaacc aaaaacaatc aaactagcca gacaaaaaag
    29941 aataatcaaa aatagagaaa acaaaaggat tgagataatg atagtaagca aaatccctag
    30001 atcagctcgc catccggtta aaataaacat gactagaagc ggaaaaacaa aaggaatgat
    30061 ggtcaaagca actaccaaaa tctttgctga aaaaacctgt tcttgtccaa aaggcagagg
    30121 caaaaatact tgcaggtcat ttccttcaaa aaagatatta taaatgactg atatactttg
    30181 agttaaacct aacataccaa aaagtgccac gtaataagta aagaaacctg gcaatttaac
    30241 aaagttcata gcaaacatag caaatccgta aatcagtaaa aaaatcagcc ctgaaaaaag
    30301 attttgagac aaaagataga tagttaatcg ctttcccttt tttcctttct ctcttgcttt
    30361 attcgtgagc tgtggattaa catataaaag attaactcga attaattcta ataattgtcg
    30421 cttatacata cggtccatct cctgtcgctt gccttccagc cattttcaaa taaatctttt
    30481 ctagcgtttc atcaggtgag ccattcaata attcactaac tgccccctga taaatcaatt
    30541 cacctttctt caaaatagcc agtttatcgc ataactgttg tgcggtatcc aatacatgtg
    30601 tagaaaaaat gactgttttt ccttttgcgg catgagcctt catcatttct ttcaaatcaa
    30661 atgctgcttg aggatcaagt ccttgcaaag gttcatccaa tacccaaata tctggatctg
    30721 gcagcaacgt gccgatcaaa atcgtttttt gacgcattcc atgtgaaaaa cttgcgattg
    30781 tttcattttg atgactatac atatcaaaaa gcgctgtcaa ttctgctaaa cgcttttctt
    30841 ttttttgtgt gtctaattca taggcagctg aaatcaagtc ccaatattct ccagccgtca
    30901 attgtaaaaa aatatctggg gaatcaggca cataaccgat tttttgtttg atactcaatc
    30961 gattttccgt caatttcatt ccatctacta aaatcgttcc cgatgatggt tcaataatac
    31021 taactaaact tttaatcgta gttgattttc cggcaccatt atgtcctaaa aatccaaaaa
    31081 tttccccttg tcttatcgag agagacaagt cttttaatgc ttgttttttc ccgtaacttt
    31141 tacttacatt gatgaattca atcatttctg tactcctttt gtttgttatt actttttatt
    31201 gtacccttcg ttattggtgg agtaaatgtc aaaaagagtg cataacaaaa aaggatagaa
    31261 acgactaggc tgctacttgg gttgttctct tctacaggaa aacactcttc taacaggtaa
    31321 gatatgagtc tttgttttct ttaaaatgat tcattttcta tcttttcttg cataaaattc
    31381 tttagtttat caatacttct ctttcccatc tctagttgtt ctccatttgc aaatgttact
    31441 atttcgttta ctctgctaat agatgtaatg ttttcagtat taatgatata agcttttaaa
    31501 tctttacata aatactcata ttcgagtgat tttttatatt ttttaattgt gccgtttacg
    31561 agaatctctt catctttcaa tactaggcct attttatttt tataacctgg catgctcatt
    31621 agataaagga tttcatcgta atggatatag tgatcgctat taccataacg gacagttgtc
    31681 cacctttttt tcgtagcatg ttgaacagga tagttttctt tttctttcaa taagtaactt
    31741 tggatgcttt ttttattttt ttcataagtg aattctttta tcaaataacc actaggcgta
    31801 atctttcgat taataacagt tattgcttta ttcggatgag acgttagata aacaatttta
    31861 cacttttcat tcttttctct aagcatttcg cctagttcga taccgctata ataggcgttc
    31921 aaatcgatgt ctaggaaaaa aatatctgag gaatagattt cattattttt aatgaattca
    31981 acaaattgta taacgttcaa tccctgaacg atctcaaatt tccaaggact taataaaatt
    32041 ctggattctt ccaaaatttc tactagcatt ttttcaaaaa ccaaactatc atccaaaata
    32101 aatatacgcg ttaccataaa aagtacctcc actcgatatt ttactatcaa aatcatttca
    32161 tacaactttt caacatacat gttaggaata aattgtaatt ctcttcacaa tcttttccaa
    32221 cacctttgaa accgatatca aatactttca ggatgctgct tctaaaataa atatcaaaca
    32281 aatgaataca tcatgcaaaa aaagccagac aaccgacgtc cttgcgtgtc agctgtctga
    32341 gctatgttta tttattttgt tcttttaaaa agaacgatac acatactgat ttttcggagc
    32401 agagactttc tcagcgtttg taacaactac agatgggatt tcacgcttga atggttgata
    32461 atagtctgat tggatggttc cttctatttt ataccattca tcatttttaa ccgttactcc
    32521 ttccggcata tgcgtcaaca aaccaaagac tcctgaatct gccacacaat ggataatgcc
    32581 gaatcggaac aagaagatat ctgtattgct atcgttcggt gtttggtaaa caaatccttc
    32641 atagctgatt tttttgccaa tgaattcgct agggtaatta taaattagct ccataacttc
    32701 taaatagttt tcatctgtga tcttgatagt ttgcttatcc ccatactttt ctttcaactc
    32761 attcatttgg tctaagtagt ctgatttgtt gaaataaata ctggtatccg gctttaagta
    32821 ttgtgtctgc atctccggat cccctactga ttctttactt actgggaaat taaatccttt
    32881 ggcttctacg atcgtagtgt cgagactaac tgttggaaac aacgtcccca cgattactgg
    32941 caaagctagc agtacataag cgattccacg ttgataaggt tttgacaacc catggtcatg
    33001 atcgtgctcg tgtgcctttt cttctgcttt tccgtttttg acccacaaat acagctgaac
    33061 taaagccaaa agagcagata aaatcattga aagaatagct aagtagcgat aatggacatt
    33121 gatatattga tcgagtttgc cagaaacttg caagtacatc atcaattcga aatacccaga
    33181 taaaatcaaa aaccgcagca tattttccct cctaaataaa taatgtgaat ccaataacgc
    33241 taagggcaat cagtccgatc agcgataaaa taaagcgtcc tgtaaaatat cgtttcatca
    33301 tcagtagatt tttgatatcg accattgggc caaagaccaa aaaggcagct acaggtgctg
    33361 tgccgaacag acttaacaaa gaagatccta taaacgcatc tgcttctgag caaagagaca
    33421 tcgtaaaggc caataacagc atgatgataa tggctaaaat ctttgttgag ccgagcgtta
    33481 gcataattct agttggtaaa taagtctgca tcgcagctgc gattaatccg ccaatgatca
    33541 aataacgacc tgtatcaaaa aattcgtcga ttgaatgtgt caacacatgc ccagtttgat
    33601 ggatcagctg attttttggt tcattcttct cactttgttc ttcttcatgg acatgatgat
    33661 ggtgattttc tgctacttta gacgtgattt tttctttcaa tacagcgtct ttttgaaaat
    33721 aggcaagcca gacaccaatc acaagggcaa caaaaaagct gcctatcacc cgccagcttg
    33781 ccatctgcca agaattgcca aatgcgataa aagtggaaaa aatcacgatt ggattgatga
    33841 tcggagcagt cagcataaaa gcaaacgctg tgtgaactgg tacgcctttt ttaacaaatt
    33901 gatgaacgat cggtacgatg ccgcattcac atgaaggaaa gaaaaatcct aagatcgaac
    33961 cagtaaaaat agagaagata cgattttcag gaagccatct cttcacacgt tctggggtca
    34021 aaaatacttg taaggcgcct gagataagac agcctaataa tacgaaaggt aatgcttcaa
    34081 taacgatcga taagaaaatc gtactcatct gcaaaaccga atttggaata aaagaaaaca
    34141 tgagtttcct cctttttatt tctagttcat tcgctttgca aatatacgct tttattcaaa
    34201 aaaaacaagt tgctctgtaa atttttacac aactcttatt ttttaccaaa gcacttcaat
    34261 tgactttttc tgttattccc attaaattaa ggtctcatac atatcacttc tatcataaaa
    34321 gggagaataa aaatgaaaca aaccactaac ttgactgaag ttcaagacat actgcaacag
    34381 tcatccgttg ccgtcattta tctttcgatg cctaattgca gtgtttgtca cgctgttcgt
    34441 ccacgactag aggaacttct cacacattat gatattccgg cacttcattt ggatgcattt
    34501 gaaacaccag aagtagctag taaatttgaa gtgctgactg cgccagttgt cctgattttt
    34561 catcaaggaa aagaagtctt tcggcaagca cggttcatcg actttaaaaa aatccgttat
    34621 ctactagatg aactgacagc agaagatgat tccctttctt atgaagaaat cttccgaaca
    34681 aaataatcgt tgtccaaaca gaaaaaagcg attgaacaag tgaaagtttt gccttcattt
    34741 gttcaatcgc tttttatttt tattctgctg tattttcgga atgcgcattt gcgtcagaat
    34801 gcaagaaata gatcaaggtt tgcaattcat tcgtcaaatc aacattttgg atcaatacat
    34861 ctgacggagc attcaatcga gcagcggtaa agttcaagat tcctttgatt cctgcttccg
    34921 ttaactgatt gactacttct tgtgctcttt cagcgggtat cgttaaaatt gctacttcga
    34981 tttgttggat cttgatttgt tctgacatat cttccattgg ataaacgggg ataccgtcta
    35041 cgatgcgccc aacgatttcc tcattcacat caaaagcaca actgatacgt atgctattac
    35101 tttgatggaa tttgtatttt agtaaagcac ttcccaagtt ccctacaccg atcagcgcaa
    35161 catttgtcaa ttgatcgtcg tttaatgtct ttgcaaaaaa gtgcataaga tcttctacat
    35221 cataaccata cccacgtttt cctaattcgc caaaataaga aaaatctcga cggatcgttg
    35281 cactatctac ttgaacggct tcacttaatt cagttgaaga cacttttttc tttccagcat
    35341 tatttaaaat ccttaaatag cgataataca aaggcagtct tttagctgtc gcctttggaa
    35401 taatatgatc tttcacgaaa tgacctccac gtattgtcta attacatctt tgatttctcc
    35461 atcatagcag tatttatagg aaaaaatcaa ttccattgct cagatattgt gaaattttat
    35521 tctttattca tttatttatc atttctgcaa atctcgcagt ataatggaat ttatggtaga
    35581 ctactaattg aaaaatagtt ttttatttga ggagaattca caaagtagaa aagaggattc
    35641 catgatatta ttacaagcca atcagattgc tcgccatttt ggtgcagaag tcttatttga
    35701 aaacatacat ttagaaatca gtacaggcgc tcgtgtcgct ttagttggca gaaatggcgc
    35761 tggaaaatcg actttattaa agatcattgc tggaattgaa gcacctgatg aaggaaagat
    35821 cgctaaaaat aaaacagcga ctctcggata cctcgctcag gacacaggac ttgattccaa
    35881 tgaaacagtt tggaacgaga tgctgaaagc ttttgaacaa gttagacaaa tggaagagcg
    35941 gatgcgcgag ctagagattt tcattagcga aggtacgcca gacacacctg cttatagttc
    36001 ttatttaaaa gaatacgacc ggctgcaaca cgatttttca gatcgaaacg gctatggtta
    36061 tgaaaatgaa attcgttccg tattgcatgg gtttaaattc gattcttcat tttatgatca
    36121 gaaaatcgat actttatcag gcggacagcg cacacgttta gctttagctc gcatgctttt
    36181 gcaacaccct gacattttga ttctagatga accaacgaac catttagata tcgagacact
    36241 ttcctggctt gagaattatc tgcaaagcta tactggtgca ttattgattg tttcccatga
    36301 ccgttatttt ttagataaag tagtcaatga agtctatgaa ttaagcagaa gaaaaatgcg
    36361 ccattacaaa ggtaactatt cgaaatatct agatttgaaa gcagaacagt tagcaagtga
    36421 atggaaggct tatgaaaagc agcaaacaga aatccataaa ttagaagact tcgttgctcg
    36481 gaaccttgtt cgcgcctcta ccacaaaacg agcgcaaagc cgcagaaaga cattagaaaa
    36541 aatggaccgg ctggatcgtc ctcaagggga tgaaaaacaa gcaaactttc tattcagtat
    36601 agaaaagcct tctggaaatg tagtcttgca aatcgaagat gccgctatcg gatatgataa
    36661 tgtcacctta tctgaaccaa tcaatctaga tatccgtcgt caagaagcga ttgctctagt
    36721 aggtccgaat ggtatcggga aatcgacgtt gctgaaatca atcattcacc agatcccttt
    36781 tatccgtgga aaagaaacgc tagggacaaa tgtcaccatc ggctattacg atcaaggtca
    36841 agctgatctg catacaaaca agacgatcct agcagaattg tgggatgagc atcctaccac
    36901 tccagaaaaa gagatccgaa gtgctttagg tgctttctta ttttctggcg aagatgtaga
    36961 aaaaccaatc cctctgctaa gtggcggtga aaaagcacgg gttgctttag ccaagttagc
    37021 gatgaacaaa gaaaattttt tgattttgga tgaaccaaca aaccatttag atattgacaa
    37081 caaagaagta ttagaaaatg cattgatcga ttatgacggc acactgcttt ttgtttccca
    37141 tgaccgatat ttcatcaatc ggatcgcgac aaaagtcgtc gaactctctg aaaatggcag
    37201 caaagtctat ctaggagact atgattatta tttagagaaa aagcaggaag aagaagaaat
    37261 cgccgaattg ttggcacaag atgagccaga atctgctcct gctcccacga acaaatctga
    37321 ttattaccaa agcaaagaac agcaaaagct tatccgtagc cttcaacgaa aaattactca
    37381 ggttgaagaa gaaatggcgc ggatcgatga atggatcgat cagttggaac aagaaatggt
    37441 cgcgccagaa aacctggaag atcacgtaaa actcaatgag ctgaaccaag atttagaagc
    37501 tgctagacaa gatcaagaaa caaaattgac ggaatgggaa gaactaagct tggaattaga
    37561 agaatatgaa aattaacgaa aaaaccaaaa cagaaaccat tcatgctgtt ttggtttttc
    37621 tttttttatt ttatcaaaca aaaattccat atttaccttt ttcaccaata agaagaccaa
    37681 ttactagtca ttctcactaa agcttctaaa taatagtaat caccccaaat acaaggtgta
    37741 tttaccccat tatttttggg cttattataa acagactgtg ttaaaaagcc atcttcttct
    37801 tccgttgtag catatctttc tttcaattgt cgcataattt tccaaacagc agactggtat
    37861 aagttctttt ctgttttgtc taatagacct gattctatta attctaataa tccacaaacc
    37921 atgatcacca tactagatgt atctttttct tctctgctag aatcatcaaa gatcaaatcc
    37981 caataacaaa tggtatcttc tggcaaccga ttcataaaat aattggctaa tattttgctt
    38041 aaatcaaaat atttttgttc tttcaaataa cgataactta atgcaaaacc gtaaatcccc
    38101 catgcttggc ctctagccca acaggaatta tcactataac cttgatgcgt acttccatat
    38161 cttggttttc catctttgac atccatataa aatgtatgat aagttgaacc atcttctctt
    38221 actaaataat ctgctgcatt ttgaatatga gcctgagcag cttttttata tttttgattt
    38281 ccagtttctt cactcgccca atacaataat ggaagattca tgcaacaatc catgatcatt
    38341 ctaccttgtt gtgaaggatc actaggatct ccccaagctt gtataactcc tgccttctcc
    38401 caaaaacgct gaagtaatgt ttctgcagca tcaattgaag cttccttcat ttttcgattt
    38461 cccgttattt tataatctgc tacggttgat aaagaataca aaaaaccaag atcgtgatga
    38521 ttagtgataa tttgacagtc aatcctgtgg ataaaatcta tatctgcttt ttcagctgtt
    38581 tgttgaaata aaggatcacc cgtcttctca aataacaacc aattaattcc tgtccaaaat
    38641 ccttctgtcc aaccaatatt gtctcttaat ggataacgtc cttttatagg acactcgctt
    38701 gggaattgat actgactgtt actgatacgt ttgattaacc tctccgtgtg tctgcgacaa
    38761 cgctcgatct cattattcca ttctttttcc attaattctt tataacattc atttatccat
    38821 ttttctggat gtattatctc ttcaaacatc actttatcaa gcatttcccc accagccttt
    38881 agcataattt tagtcttttt ttattgtttt tattttggat agttagcccg gttgtcccat
    38941 caaaatcaat tttgggacga ttgttccata cttctaaact ataatcccga tcttgatgag
    39001 caaccactcc tgttccgagc caatgggttc cttttccaaa tgtaccctct aatccaggaa
    39061 taaaagtgtt ttcccatgtc atcaagtttg tattgggcaa acccataata gctgtggatt
    39121 ttcgtttaat agtatcgtca cttaaacaga taatacctga aaagccagct tcactcaccc
    39181 tatagttttc cttgtcttct tctatgatta ttccttcttt ctcaggagaa cattcaatag
    39241 caaaccctgt ctcatataga acatattctg tatctaattc tactttgtgt acgcgaatct
    39301 gccagccttc aaaaggaata agccaagttc tgatttttgc ctgtaaagta ggttcccatg
    39361 tagaggcaag tacctctttc ttacatacaa tgtctcgtac attatttcga acgatgaact
    39421 gtccataggt tttgatgctc tcattcttaa aactggtcgt gatatatgtg tccgctcgct
    39481 gaatccctag cattgaatcc attgccattt ctgctttcaa ttgattcgct cgcggtatcg
    39541 aaaaaccaaa ttgactagaa taagcaaatt ttaaatattt ttcattggtc aatgtatgga
    39601 aatttggccc taattgtccc gcattcaaaa aaaatgtatg tccattatca tgttgtatga
    39661 gcaaattggc ttctgaaaga agtttagttc cttcacgaat aggcataggc atttctttag
    39721 ccgtccaata ctcatggtct tcaggtagcg ccaacaataa aaaaatctta ttcagccata
    39781 atggagataa cgtactatta tagggttcag tcaatgtcaa ttgagggtag gtataaccaa
    39841 tattcaggat acctttttca tcaaatattt ctttttgcat ccaccatctt atattccgat
    39901 tgactaaccc cttgatttca cctaatttaa aaggcaaaag atcggcccac aacatagctg
    39961 accaaaagct tgaaactgca aaacgataaa tcatgcttcg accaaaaggc acatttgcac
    40021 catcttccgc aaaaaaatga atatagtctc tagaaaaatc aatagctcgg ttcttatata
    40081 tctggctaat gggcttttct ggttctagta cgctataaat caaaccataa taatgaaatg
    40141 caaaaggatt ataataatct tggcgacctc ttgaactgtc tcgataccag ccattttgaa
    40201 gataacaatt ttctatatta tcaaatgctt ctttcagtgc tgattcttta actggataac
    40261 caaatttttg gataattgtt ccgacaatta tcttaaaaaa ttgccaatta ccatctgcac
    40321 attcatattc aaaaatttgc gagaaccaat gaataatctg gcttttttct cctgtatcta
    40381 attttttcca taataattgt tcatgatgat ataacgctaa taacattgcg ggcatttcta
    40441 ccatacgctg gtctctttca tgtatttctc cccaataatc gggatgggaa ggatctgttc
    40501 cagcttttat tcctgataga attaatttca accatcgttc atctaattgg tcaattgcgg
    40561 gccccgctcc ccataaaacc cgagagaatc cttccattcc tgcaatttta tttccatatc
    40621 ctaccccttg atgtatataa tcaatttgtg cgccacttgc tcgataaaac ggctggagtg
    40681 gttgatttat ctttttaaat aagtcaaagt aatcctgtct ggtccttaat agtggtactg
    40741 gatgtttcat tgtattttct cctcttttta ctaccaaata gctaattccg actgttctaa
    40801 tcgaagtaag ccttcaataa aaaaataatc agaatagatc agtggcacat tataagtcag
    40861 ttctctatgg tatgcttctg ctccgcctcc aatgatccca tcttcatcca tattccaatt
    40921 tgcatagtgc ttttctgtct tttggagtat attgatagca gcttcatgat acatttttga
    40981 tcgtacagag gaaacatatc ctgctaattc cagaagaccg catgcagcgc atactccagc
    41041 actggtatca atattcgaat cttttacagc aaaatcaatg agaggaatat aaccagtttt
    41101 ttcgattttc tgaataaaat ttactgctat cttttctgct atagctagat agtacggatt
    41161 ttttgtgtaa cgataactta acgcgaatcc atataaagcc catgcatttc ctctgctcca
    41221 acaagaattc tcattgtatc cttgcccgcc aagtaaccga atatatttcc ctgattctgc
    41281 atcaaattct gcgatatgcc cggttgatcc atctttcctc actagatact tagctgttgt
    41341 atctgcatgc tgccgagcaa ttttagagaa cctcggatca ccagtttccc tcgaagccca
    41401 atacagtaat ggtaaattca tcatactatc aataatcatc caaccaggtt tatggtcatt
    41461 ccatgctact aaatagttcc ctgaaatatt atagcgtcca gcaagtaccg tagctgcatg
    41521 taaccctagt tgtcgactat gtttgttttg agactgttga taatgtgcaa tagccgatgg
    41581 taagaataaa aaacctacat catgatgaac gtctgaaaaa tggtacaggg cagattctaa
    41641 taattgttct tgttgtattg ctgcctcttt gaacttttct cgttttgtct tgtgaaagag
    41701 ctgccataaa ataccactcc aaaaaccatt ggtccaccag tcgattcctc tgtcctttat
    41761 tacgtctgta tattttccgt tgtaagaaat atatggaatt ttattcccca ttctgtctaa
    41821 ttccgcatct atcttttcag aagctacatt caaaattttt cttgaccatt ccttcgtctg
    41881 ttcattcatg gatatcccgc cattctttta atttttatga atgtggagtt gctcctagaa
    41941 cgaactagat ggttaacatt cgttattttt tttacttatt tgcagctcca atgtcattct
    42001 ccttaaattt agactgcgcc cacacataaa tcaagaccat tgggatcact gaagttgcta
    42061 aaattagcat aattgcgcca taattaattg gctcacctgt actagaaacc gtcatatttt
    42121 tgataattaa gggaaccgta tatttatctt tatctgaaag catgactaat ggaaatagat
    42181 attgattcca acttcccata aagataagta aaccactagt aataatcgta ggtgataaaa
    42241 tcggtacagc gattttcgta aaaatcaccc actcattggc accatcgatt ctggcagcct
    42301 ccatcagtgc tgtaggaaat tgactgctat attgtcgcat cataaacact gaagttgtac
    42361 tggcaatcga agggatgatc acacctgcat aagtattcga taatcctaaa cgactcataa
    42421 tgtaaaataa aggaatcaat gtggtaaaaa aaggcaccat cctagatagc ataactgtat
    42481 tgaacaacag tttattcccc ataaaacgat actttgctaa tgcataaccc gccattgtag
    42541 aactggctgt agctaaaact gtactgatta cagcaataac aatcgaattc caaataatca
    42601 agggataatt atatctcgcc atgatggctt gccagttttt taatagcata tccccaaact
    42661 tgaaattgat tccgccactt aaaatttctt gattactttg cgttgaagct acaatcatat
    42721 ataaatatgg catcaaaaat attaaggcac caaacacaat aatgacgtac gtaaaaattc
    42781 tgctttgtat cttttgttta gtcattttta tcacctccga atttaaattg aatagccgat
    42841 aatataacag atacaaacac catcgtccag gcaatagcag aggcttttcc aaaatcaacc
    42901 atttcaaaac ttgttttata taaattgact cctacgacca aagctgaatt ttctggtcca
    42961 ttggaagtcc caaagaatat atttgggata ttgaaattac ccaagccatt gatagtggct
    43021 aaaactgtgg ccattaaaat gattggcttt agcatgggga tcgttaataa aaagaattgc
    43081 cgaaatttcg atgctccatc tatttcagca ctttcgtata tctctttaga aatcccttga
    43141 agaccagcta aaaataaaat agtgttatat cctacactaa gccaaatcat cgtgatgatc
    43201 attgatattc gtatccaaaa aggatttgtt aaccactgta caccgttaat tcctagcgca
    43261 ttcaaaaatc cattgaataa cccagtcgga ttgaaaaaag tcatgaatac ggaagctaca
    43321 gccaccgttg atgtaatggt tggaatataa tagacagttc taaaaaatcc ttttcctttt
    43381 aactgtgctg aattcaataa aacagcaaag taaatagcta atagcatcgt tattggaatt
    43441 gatcctgcca tgataatcaa aacattcgtg taagatttaa taaacaatgg atctcggaag
    43501 atagctagat aattgtcaaa tccaacaaat tcaaatgagt agccaatttt cataaaacta
    43561 aaagcaaacg agataatgat gggaatcaaa atcgtcacaa taaagaaaat aacaaaaggt
    43621 gtgaccaatc cataagcact ttttttatga gacgtatctg ttgctttttt cttgctgttc
    43681 tttattgtct tgcttggtaa cgaagattgc atcatcgtta agtcctccta atatttttta
    43741 atcaccagtt aattttacgc cgtacttatg agcaaaattt tctgcttctt ttagatatga
    43801 attttcaaaa tcacctgttt gccaatagtt atatgcagcg gtagtcaaat aagacgtagc
    43861 atctgaataa gtggctggta aaacagtatt tgatgtattt tcattgattt tattcaatag
    43921 ttcatagtat ttttgtcctc cttagtagtc aaactttttc tcagctgctt ctgtttgata
    43981 ggccaatgag ttagatgtag ccacgcccag ctccagtgcg ttggctaagc attcttcatc
    44041 tgtcagcata aatgtaagaa attgttgtgc cacttgtgga tttttggcat ctttagggac
    44101 ataaaaactt gatcctcctg atactgcacc ttttcctgga ttttcttttg aaaaaggaat
    44161 cagtggagcc atgcgccatt tgtcagatgc atcaggaaaa ttcaaagaca tattcgtagc
    44221 ataccagccg ccagcaacaa acattgcaga ttcttgaaat gctttctcag catcttgtgc
    44281 accgtagaaa tgtacaatat ctgagtcgat catttctttg attaactttg cagcatgttt
    44341 cgcttcttta gtattcagac ggatatttcc ttcttcatca agcaaagatt gattctgctg
    44401 ggctagcatg ttgataaaca attcttggtc cccagattct ggcaaggcaa ttccaaaact
    44461 accagttttt tcttttaatg cttttgccac ctggatatat tcttcccaag aactgatttc
    44521 ttcaaaatct acacctattt cagcaaattt ttttggttga taataacaaa gtgctggggt
    44581 aaaatcacta gcccaaggaa taatcgtttc attactcgtt tgttgacgca aaatattcaa
    44641 tttttgatca taaaactgat cgccatattt gtcataaaat ccatattcat cagcactata
    44701 aaaagcatct tgaaattttt ccagcacacc tgctgctgaa gtgtctgcca tggagataat
    44761 atccggcata tcttcgtgtg ttaccaattt tggggtgatc atttgtactg ttgctgttcc
    44821 cgaagctaca ttcacaattt ttaagtcaat atttgctcca gttttgcggt tatagatttt
    44881 tgcagcattt tcaacatagt ttgtcagttt gccgtttgcg acatatactt ctaatgtagt
    44941 ggcttttttt atcattggat ctgcgatgtt tgctgttact tcttcgttag tttttccaca
    45001 tgcacttaag ctgaataata gggtaatgtt tagcaaagct atcaccaatt tgtatctttt
    45061 tttcatgtct atcccttctt tcttttcaag ttcttatata aaacgctttc acttatgtat
    45121 attaacggaa ttagtaacac aaatatttat ataaaaaaat attttacttg tcgttttggc
    45181 ttttcatttt tgttataata gtcattaatt ataaatagaa agctttttat ataaaaagag
    45241 aaaggaaagt ggttcttttg ttaacaaaca accaatcctc caatcttgtc aaaaaaacac
    45301 taacctattc catagatacc catcttcatt tatctgctgc tccctatttt cgactactaa
    45361 taaatgaaag cgctaattta tatgctgaat ttgcacataa atctatagaa ctagataatc
    45421 cttccctttt attcattgat aaacagcaag aagtccaaat cttttctact caaaaggaaa
    45481 cacaaacttt tatcattatc cagttttatt ttgatgagca attattagca catattacgg
    45541 gacaatcttt ttctatagat caagaaataa catctatcat tacttttctg aaaaatgaac
    45601 agttcaaaat tgattatcta aaacatagta agccagctat ttcctatgat caggaaatca
    45661 attctttttt catactatgc caacagatga gcattcattt gctttcctta ttagttactt
    45721 attgtctgca aaaaattcaa ttgtcttcct taccaaggca ttatcaacag gaacttgctt
    45781 tattgacaat accttcaaat gagaaagtca ttcctaaaaa aaagcatatt ctttattcag
    45841 atgaattagt tgatccaatc atacgatatt tagaagaaca tctttcagaa aattttttgc
    45901 ttgaacaatt agcccaaatt ttttttatca gtccagccag cttaaaaaaa cattttagaa
    45961 aagtgaatgg aaaaagtgtt attagctatt ttaaagaact aaaaatggaa aaagcaaaac
    46021 gtctcgtgct agaaaatgaa ttaacctata cagaaattgc agatatatta ggatttcatt
    46081 cgatccatca tttttcttca gcttttaaaa aatatacagg gttatcccct tcaaagtatt
    46141 atctatcctt aaaatagaaa aaaattttta ggttttatcc acaaattatt tctctatatt
    46201 ttctgtctat tcaaaataaa caataatttt ccggcacaat tatttgctgt tttttaccat
    46261 aacatagtac gatcaacgta gaaaaggaga tgtttttatg aaagttgttg tcattggcgg
    46321 tgtagctggc ggtccttcat ttgccactcg tttccgtcga ttgaatgaag cgcacgaaat
    46381 cattatctat gaacgcggag aaaatatttc ttatgcaagt tgtgctttgc cttattattt
    46441 aggaggtgtg atcactgacc gtgactcgct gatcgaacgt acaccagaaa tattgaaaac
    46501 aaaaaacaac atcgatgtct ttactaaaca cgaagtaaca gcaatcgatc cttctactaa
    46561 gcgattaaca gttaaagacc tatccacaaa tgaagaaata aaaacagatt acgataagtt
    46621 gatcatctct tctggtgcta gaccagatta tccggatatt cccggagttt ttgaagcaga
    46681 aaacggcttt gtcctccgta gtgtgacgga tgcggatcga atcaaatcgt tccttgaaga
    46741 aaaaaatcca caacatgtcg tcattcttgg tgcaggtgtt atgggtctgg aattagctga
    46801 gaatttcaag catcgcggct tagacgtgac tttaatcgat caattgccac aagtcgcttt
    46861 cccttatgat ccagaaattg ctaatttagt ttatgacaaa ttgctgaaag aaggattagc
    46921 cgttcattta gaaacaagag ttactgagat ccgtgataaa ggtcgagaaa tagtattatc
    46981 agatggctcc gtcctttctg ctgatatgct aatttttgct gttggtgttt ctccgaagaa
    47041 tgaagtggtg aaagcaaccg gcatacaatt atcagataca ggtcagatca ttgttgatga
    47101 ccagttacaa accaatctgc cggacatcta tgcgattggc gatattatcg aaacgactag
    47161 tgtagtgact ggtcagccga tccaaagtat gctttccagt gcggccaatc gtcaaggaca
    47221 tatgctggca gatattttaa atggtacgcc tatgcgctat cgcggatata ttggtgcagg
    47281 tgtcgcaaaa atctttgatc atacagcaag ttatgcggga atgacagaac atgaattaaa
    47341 agcatcaggc ataacaaatt ataaaactgt ttttatcact ccctttgacc atgcctattt
    47401 ctatccagaa gctacaagat taaatctaaa gctgattttt gatgcagata gcggtcgtat
    47461 tttaggtgga caagcatttg gagaaaaagg tgtcgataaa cggatgggag aactttctgt
    47521 agcaatcacc ggaaacttga cagtctttga tttgcctgat ttggagttgc cttactctcc
    47581 accgtattct actacccgtg acccgttgaa tatagctggt tatgtcgcaa tcaatcaaat
    47641 gacgaatatc gtagaaacga tcaaagcaag tgatataccc gaaaacgatt tgaaagaagc
    47701 gttcttttta gatatacgtg aacctaataa agcaccttct ggcagtatct cggcaacaaa
    47761 aaatattcca atgaatgagt tacgagatcg aatcaatgaa atcccaaaag ataaaaaagt
    47821 ttacattact ttcagaagag gattgaatac ttatacttct gcccgaatct tggcaggttt
    47881 gggtatcaaa gcgattttga ttgaagaata aaaaaacgac cgcggtgggt agccgcggtc
    47941 taggagttat ttttacttga ggagtaaaaa tgaaaaagta tatagggttg ttggttggta
    48001 tgtatataga atagaagata aatgtgaaga aattgtgcat tatttcttca catttattag
    48061 gttatagttt aagaaagttt aaacattgcg caatttaatt attttagctg tttcttttca
    48121 taaaaaaaca tgttgtgact ctgagacaaa tcatagtcca tagtgatgtc tctagagtaa
    48181 ctacgcctaa tattacgagg catcatatta atctatcagc actagtacct aaactagcat
    48241 ccctttcgaa tattttttct tatataataa agtttgcttt cactcctcta atctcaccaa
    48301 atcgactggc ttgcgttgtg tgatactagg aactgattgg tttagaacga cttttctatt
    48361 gtaatcatat ttttcgccat cctcgttgtc ttctaatcct tcaatgaatg atccctaatg
    48421 tgtgtattaa ataatttaat ttttttgttc ctatttattt aa
//
LOCUS       DAFEIE010000014        46151 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFEIE010000014
VERSION     DAFEIE010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46151
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.014"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            46..2211
                     /gene="acm"
                     /locus_tag="LP345_000907"
     CDS             46..2211
                     /gene="acm"
                     /locus_tag="LP345_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBL1759708.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2483..2968)
                     /locus_tag="LP345_000908"
     CDS             complement(2483..2968)
                     /locus_tag="LP345_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBL1759709.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3058..3403
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3448..4089
                     /locus_tag="LP345_000909"
     CDS             3448..4089
                     /locus_tag="LP345_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1759710.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLSVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4108..4743
                     /locus_tag="LP345_000910"
     CDS             4108..4743
                     /locus_tag="LP345_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1759711.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4761..5576
                     /locus_tag="LP345_000911"
     CDS             4761..5576
                     /locus_tag="LP345_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1759712.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5895..7331
                     /locus_tag="LP345_000912"
     CDS             5895..7331
                     /locus_tag="LP345_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1759713.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7520..9967
                     /locus_tag="LP345_000913"
     CDS             7520..9967
                     /locus_tag="LP345_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL1759714.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10197..11264
                     /gene="rlmN"
                     /locus_tag="LP345_000914"
     CDS             10197..11264
                     /gene="rlmN"
                     /locus_tag="LP345_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL1759715.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11457..12560)
                     /locus_tag="LP345_000915"
     CDS             complement(11457..12560)
                     /locus_tag="LP345_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1759716.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13113..13661
                     /gene="aac(6')"
                     /locus_tag="LP345_000916"
     CDS             13113..13661
                     /gene="aac(6')"
                     /locus_tag="LP345_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL1759717.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14206..15867
                     /locus_tag="LP345_000917"
     CDS             14206..15867
                     /locus_tag="LP345_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1759718.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(15937..16284)
                     /locus_tag="LP345_000918"
     CDS             complement(15937..16284)
                     /locus_tag="LP345_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBL1759719.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16368..17309
                     /locus_tag="LP345_000919"
     CDS             16368..17309
                     /locus_tag="LP345_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759720.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKTQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17310..18353
                     /locus_tag="LP345_000920"
     CDS             17310..18353
                     /locus_tag="LP345_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759721.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18359..19429
                     /locus_tag="LP345_000921"
     CDS             18359..19429
                     /locus_tag="LP345_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759722.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19419..20372
                     /locus_tag="LP345_000922"
     CDS             19419..20372
                     /locus_tag="LP345_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1759723.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20384..21394
                     /locus_tag="LP345_000923"
     CDS             20384..21394
                     /locus_tag="LP345_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1759724.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21679..22500)
                     /locus_tag="LP345_000924"
     CDS             complement(21679..22500)
                     /locus_tag="LP345_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL1759725.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22597..22875)
                     /locus_tag="LP345_000925"
     CDS             complement(22597..22875)
                     /locus_tag="LP345_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759726.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23143..25152
                     /gene="metG"
                     /locus_tag="LP345_000926"
     CDS             23143..25152
                     /gene="metG"
                     /locus_tag="LP345_000926"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBL1759727.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25631..26218)
                     /locus_tag="LP345_000927"
     CDS             complement(25631..26218)
                     /locus_tag="LP345_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759728.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26393..27715
                     /locus_tag="LP345_000928"
     CDS             26393..27715
                     /locus_tag="LP345_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1759729.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            27870..28646
                     /locus_tag="LP345_000929"
     CDS             27870..28646
                     /locus_tag="LP345_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL1759730.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28639..29208
                     /gene="rnmV"
                     /locus_tag="LP345_000930"
     CDS             28639..29208
                     /gene="rnmV"
                     /locus_tag="LP345_000930"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBL1759731.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29201..30085
                     /gene="rsmA"
                     /locus_tag="LP345_000931"
     CDS             29201..30085
                     /gene="rsmA"
                     /locus_tag="LP345_000931"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBL1759732.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30536..31165
                     /locus_tag="LP345_000932"
     CDS             30536..31165
                     /locus_tag="LP345_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759733.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(31289..32398)
                     /gene="ugpC"
                     /locus_tag="LP345_000933"
     CDS             complement(31289..32398)
                     /gene="ugpC"
                     /locus_tag="LP345_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBL1759734.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32607..33029
                     /gene="mgsA"
                     /locus_tag="LP345_000934"
     CDS             32607..33029
                     /gene="mgsA"
                     /locus_tag="LP345_000934"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBL1759735.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            33352..33888
                     /locus_tag="LP345_000935"
     CDS             33352..33888
                     /locus_tag="LP345_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL1759736.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(33928..35691)
                     /locus_tag="LP345_000936"
     CDS             complement(33928..35691)
                     /locus_tag="LP345_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759737.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(35694..37409)
                     /locus_tag="LP345_000937"
     CDS             complement(35694..37409)
                     /locus_tag="LP345_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759738.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(38188..38412)
                     /locus_tag="LP345_000938"
     CDS             complement(38188..38412)
                     /locus_tag="LP345_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759739.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            38603..41380
                     /locus_tag="LP345_000939"
     CDS             38603..41380
                     /locus_tag="LP345_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1759740.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            41461..41880
                     /locus_tag="LP345_000940"
     CDS             41461..41880
                     /locus_tag="LP345_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBL1759741.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            41892..42362
                     /locus_tag="LP345_000941"
     CDS             41892..42362
                     /locus_tag="LP345_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1759742.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            42379..43158
                     /locus_tag="LP345_000942"
     CDS             42379..43158
                     /locus_tag="LP345_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1759743.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            43145..43966
                     /locus_tag="LP345_000943"
     CDS             43145..43966
                     /locus_tag="LP345_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1759744.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            43983..45032
                     /locus_tag="LP345_000944"
     CDS             43983..45032
                     /locus_tag="LP345_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1759745.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            45045..46049
                     /locus_tag="LP345_000945"
     CDS             45045..46049
                     /locus_tag="LP345_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1759746.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
BASE COUNT        15258 a         8049 c         9518 g        13326 t
ORIGIN      
        1 atatagtagg ttttattttt agttaaaata ggggagatag aaaaaatgaa aaagtgtaga
       61 aatattattt tatcaatgtt atttattatt actaatataa catcactgat tcctgttcat
      121 gtctatgcgg atgcaggcag agatatcagc agtaatgtca cttcgttgac cgtggaccca
      181 acgaatatta cagatggagg aaacataaaa gtaaaattct cgtttgacga aaaaaaacaa
      241 aatatccaac caggtgatta tctttggatc aattggccaa gtgaaggaaa tattcgcggt
      301 gaaggattcc aaaaagaaat cccattaatg attgaaaata aaaatgttgg aactttaacg
      361 gtcagaaaag attctgcgca ggttgtgttt aatgaaaata ttaaaaacct agactcagta
      421 gaaggttggg ggcaatttga gatacaggcc agaaacgtaa ccgataccgg tgaagaaaat
      481 acgggaccat tcaccgtgac gagcggtgat aaaacagcta ctgtaaatgt gacaaagcca
      541 gcttctggtt cttcttctag cgttttttat tataaaacag gagacatgct acctgaagat
      601 actaagcaca ttcgatggtt tttgaatatt aacaataacg gcacttatgt tgaacaacca
      661 gttaaaatca gtgatgaaat ccaaagtgga caaagattag atccaagtac gtttgaaatt
      721 aatcaaatac acttaggtga acagaaggtt tatagaggag aagagggaat ccaacaattt
      781 ttacaagatt tccccagcgc tacatttaat ttttcagtaa ctgataatta cattgaaata
      841 actataccaa aaaactttgt caatcttagg aaaataatgg tgagttataa gacgatcata
      901 gaaaacccag aacaaataaa ttttgagaat cattcggaag cttggtttaa agaatttaat
      961 aaacctgctg ttgatggaga aagtttcaat catacagtta aaaatatttc agcttctggt
     1021 ggagtcaacg gtacagttag aggcgaattg aagattttca aatatatcaa tgacacagag
     1081 attggtatcc caaatgtgac tttcgaatta agacgagcag atgaacagcc tattcaagga
     1141 cagtctagta tcctgttgac ttcgaatgaa cagggagaag ctagtatcaa aggcctgcaa
     1201 gtaggagact atgttgtaaa agaaaaagaa gcacccaatt ggattgattt tgatccacta
     1261 agttcaaatg aactcaaatt ctccataaac gaaaatgata cagagggagt cagtttacct
     1321 atttataaca agaaaaaggt tacgaacatc acagcaacta aaatttggaa cggtggaacc
     1381 actccaagac cgagtattta ttttaaatta ttcagagcaa gtacaaacaa ttgggaacca
     1441 gttcctgatg cagaaacaaa acgattagac aatggaataa cttcagtgac ttgggaagat
     1501 atccaacagt atgatgatag tggaaacgaa tatacgttta aagtgcaaga agtagatcaa
     1561 aacggaaatg attatgtccc ttcaggttat caaaaaattg aaaacgggct agtcgttaca
     1621 aatgagaata aagaagtcat ttcagtctca ggacaaaaaa catgggaaga caatgagaac
     1681 caagacggca aacgaccgac gacgatcaca gtaaatctat tagccgacgg tcaaccgatc
     1741 caacacaaag aagtaagtga aaaagatgat tggcgctatc gtttcacaaa tctgccaaaa
     1801 tacagagacg ggcaagaaat catctatact gtaacggaag acaacgtgcc cgaatacagt
     1861 acgacgattg acgggtataa catcaaaaac agttatacac cggaaaaaac aaatatatct
     1921 ataccaggta gccatataac accgtggaaa aattttccag agaagacaga gagagagaaa
     1981 attagaaatc tattctctca aaaattgcaa atatttgctc atacaggaga atccagcgaa
     2041 caaagaagca attatattag taagagagct gtacctaaac agataacaaa taaatcaaaa
     2101 agcattcttc ctaaaacaag tagtaaaaaa tctagttttg ctgtaatcat tggtttattg
     2161 atagtaacta tctgtgctgg gatattctta caaaaatata aaaaagttta gttagaatat
     2221 aatatttttt gttaaatatg actgaaatca aaagaataaa attccgattt ataatcgaaa
     2281 aaagaagcat ttttatatat gcttcttttt tcgtagaatc aataaatatg gatttggcta
     2341 actatggaag aatactcgta ttagttttca gcgttcatac tagttgttac attgtttgat
     2401 tggccaaaag aatttctgat atattttgtg ctaaataaag aaaaagacgc ttgaattggg
     2461 aaataagaaa actactctat cattacaaat tttcataaac tggcagatgt tctaagtaaa
     2521 caagtatctt ttcaaagtcg gaaaaatcca taatcaacgt agtggtattg atatttggat
     2581 gaaagcctac ggtatcttga cgatcaatag cagcatcgat cacgacttgg atttttttct
     2641 ctttgtcgtg catcaatgct aatggagtca ctgtacctgc tggaacgcct aggaggtcag
     2701 gaagctgttc ttcagaaaca aaagataagc gcttttcttt taattgttca gctagttgtt
     2761 ttaaatcggc gtgcttttca tcaggcaaga tgacaagata gatttgtttt ccttttcttg
     2821 atttcaataa tagatttttt acttgcggac caggtaggga aaaagggaca tttttgactg
     2881 acgtaatcgc aggatgatcg actttttgaa aagagatacc cagttttttt agtagttcat
     2941 aagcttcttg ttcggttgca cgactcatcg cgcatcaccc tccttttttt attagtgtat
     3001 cataaaaaag agttgacaaa tgaaaaataa tcatgtaaat tacacgtaaa gttaaaacaa
     3061 atgacatcga aaagaagagt agccgttagg tgtttttaga gagtctctgg ttggtggaaa
     3121 gaggcagcag ttaaccgtga aacacatctt ggagtcgatt ttctgaagcg tatagtagga
     3181 aaatccgggg agcccgttac agctgcggtc gttgctagat gaccagataa ggctggcttt
     3241 tccgtgagga gtcggtaaaa aaaggtggaa ccacgtgatt aacgtccttt gatcttcgga
     3301 tcaaaggact ttttgttttc atctgaacgg caacgactgt gtgaggtttt ttctgcaagg
     3361 aaaaaataaa cagaggtgga accacgtata atacgtcctc ttggcatttg ccaagaggat
     3421 ttttttattt taaaggagga aaagaagatg gagtatttga ttgaagttat gccgcaatta
     3481 ttagtaggag cactcacaac attgaaatta tttttattta ccttgattgg ctcattacca
     3541 ttagggattg ttttagcatt aggattgtct ttgcatttta agccgctacg ctacttgctt
     3601 caaacatatg tatgggttat gcggggaaca ccgctgttgt tgcaactgat ttttattttt
     3661 tatgggttgc cgacgattgg gatcgttttt gatcgtttcg aagcagcact cattgccttt
     3721 atcttaaact atgcagctta ttttgcagag atctttcgtg gagggataca atcgattcct
     3781 caaggtcaat atgaagcagc gcaagttttg caattaagtc cctttcaaac ggtgacgaaa
     3841 atcgtcatcc cacaagtgac aaagattgtt ttaccttctg tagggaatga agttatcaac
     3901 ttggtcaaag attcttcctt gatctatata ttaggtttag gtgacgtaat gcgtgctggg
     3961 aaaatcgcga tggaacgcga cgcgacttta ctgcctttgc taagcgtggc aatcatctat
     4021 cttacattga ctggtattct aacaatcgta atgaaacaag ttgaaggaaa attaaattat
     4081 taccgctaac tgataggagg aagaaatatg attgaattga agaaagtgaa caaagcattt
     4141 ggtgaaaaaa aaataatcaa agatttgaat ctaatcattc cagatgggaa aacattagct
     4201 atcgtaggtc cttccggtgg cggtaaaacc acgcttttac gtatcttggc tggcttagaa
     4261 agttctgaca gcggagaatt ttatttagac ggtgtaccgt tcaacccatt cgagcttaaa
     4321 atgaaagaac aagttgtagg agtcgtattc caagacttcc agctatttcc acatctgaat
     4381 atttttgaaa acattacctt agcaccaaaa atggtattga aacagacaaa agaagaatac
     4441 accaaaaaag cagaagaatt agcggcttca ttagggatta gtgatttatt gaatatctat
     4501 ccttatcagc tttctggcgg acaaaaacag cgggtagcga ttgccagagc attggctatg
     4561 aatccacggg tattggctta tgatgaacca acaagtgctt tagatcctga attacgccag
     4621 caagtcgagc gtttgatcct atcattgaaa gaagatgggg taacccaaat tattgtcacc
     4681 catgatttag tatttgcaga aaatgtcggt gatcaattac taaaagtttc cccaattcat
     4741 taagaaagga gaagatagag atgaaaaaaa ccagttttct attcgctttg atcgcaggtc
     4801 ttcttctttt tgcaggctgt tcgaacaaaa aaacttcagc agataattgg gcgactatca
     4861 acgaagagaa aaaaatcgtt ataggtttag acgatacatt tgttcctatg ggatttagag
     4921 ataaagacgg gaagctcaca ggatttgata ttgatttagc caaagcagtc tttgaacaat
     4981 atgggattac ggtagacttt cagcccattg actggtcaat gaaggaattt gaactgaaca
     5041 atggaacgat cgatttgata tggaacggct attccaaaac gccggcaaga gaaaagaaag
     5101 tgcaatttac aaaaccttat atggaaaacg atcaagtgct gatcacacct aaagaatcag
     5161 gaatcacaaa ctttggacaa atgaataata agagattagg tgcgcaaaat gggtcatctg
     5221 gttatgatgt atttacgaaa caaccagaag tattaaaaga gatagtcaaa aaccaagatg
     5281 ctgttttgta tgatagtttt aatgaagcat tgatcgatct gaaaagcaga cgggtcgatg
     5341 gtctgctgat ggataaagta tacgcagact attatttgaa acaaagaaac gaactagaag
     5401 acttcaacat aacaaaaggt tcttatgaga gtgaggattt tgcagttggt gcacgcaagt
     5461 cagatagtac attagtgaaa aaaatcaatg aagccctaga tcaactagag aaaacaggtg
     5521 aattccaaaa aatatccgat aaatggtttg gcgaagatgt tacgccgaga aattaacaaa
     5581 taggggactg tgacaaaaga cgtgtcacag tccctttttc cgaataaaca gtgttctcct
     5641 gccaactcct tgtgactcgg agctgaatgg caggctcaca acctcttggt aaacggtgtt
     5701 caaaagccag tttttcggta ttaagccaaa tttatgcaaa aatgtagaaa gccattttca
     5761 caaaattttt cttactactc gaaactaagc gactttttca caacctcctt tacatatttt
     5821 tattttgttg tggaaggggt ttcgtgttat tctaaaagag gaacgattga aggttatagg
     5881 aaaggaagag atgaatggaa cacaaagaac ttacctcatt tccaaaagat tttctgtggg
     5941 gctctgcttc tgcagcgtat caagtagaag gagcttggca agaagatggg aaaggagaat
     6001 cagtctggga tcgatttgta cggatacctg gaaagacatt taaaggaacg aacggtgatt
     6061 tggcagtaga ccactatcat cgttataaag aagatattgc tttaatgaaa gaacaaggtc
     6121 tgaaagctta ccgcttctct gtagcttgga cacggatttt tcctaatgga cgaggagaag
     6181 tcaatcaagc tgggctcgct ttttatgaga gattgatcga cgaattgatt gaaaacgata
     6241 ttgaacctat gttgacttta tatcattggg atcttccaca agcattgcaa gatgaatata
     6301 atggttggga atcacgtcag atcattgaag atttcactca ttatgcagaa acattatttg
     6361 aggcattccg cgggaaagtc cattactgga ttagtttgaa tgaacaaaat atcttcactt
     6421 cattaggtta tttgttagca gcacatccgc caggtgtgac agacccgaaa cgaatgtatg
     6481 aagttaacca tattgctaat ttagcaaatg catctgtcat caataaattt cacgagttag
     6541 aaatgcctgg aaaaatcgga ccaagctttg cgtatacgcc aaattatcca attgacagta
     6601 atcctgaaaa tgttctggct gctgaaaatg cagaagacct gatggccaat tattggatgg
     6661 atgtctatat gtggggaaaa tatccgattg ctgccatgag gttcttagaa gaaaaaggat
     6721 gggcaccaac gattgaagct ggcgatgcag aattgctaga atctgctaaa ccagattttc
     6781 ttgggatcaa ttactatcaa acggcgacga atgcattcaa tccattaaac ggagttggtg
     6841 ctggaaaaat gaatacgaca ggaaaaaaag gttcatcaga agaaactgga gttcctggaa
     6901 tgtataaaaa agttgagaat ccatttgtcg aacgaacaaa ttgggactgg gagattgacc
     6961 cagaaggatt aaggatcgga ctgcgtcgta tcacaagccg ttaccgcatg ccggtactga
     7021 ttacggaaaa tggcttagga gagtatgaca agttgacaga agataaacaa atccatgacg
     7081 actatcgaat caattactta caaagccacg tcaaagccat caaagaagca atttcggatg
     7141 gagcagaagt cctaggctat tgcacctggt cttatacaga tttgcttagc tggctgaacg
     7201 gttatcaaaa gcgatatgga tttgtatatg ttgatcaaga cgaaacacaa gaaggatctt
     7261 tggaacgata taagaaagac agttattact ggtaccaaaa actgattgaa gaaaatggag
     7321 agaaccttta gttcacatac ttaaaacaag aaggtacggc tggatatggc cgtgcctttt
     7381 cttgataaaa tcatttagaa attaagaaaa actgtaaaat aagctgaaaa atgaaagaaa
     7441 gcgtcagttc tttcaaacaa aactttagtt cccttacttt tttttgtata atgaaacttg
     7501 atgaaatgag ggataataaa tggcacaaaa gaaacggcct actaaaaaaa ggaaaaagac
     7561 gaaaaaaacg aaaaagcaaa aacagcagca ggaacaaatg ctgacgattg gtgttgggtt
     7621 tgccttgatt ttatttgctg tcttcggctt tttaaaatta ggttttttag gaatattgat
     7681 tgcaaacggc tttcggatca ttgcaggaaa tacttaccaa atcctctgtc ttttattagc
     7741 cgtattagga ttttggattg tcattaagaa tacagagttt tcaattggta aaaaccgacg
     7801 ctggtttggc ggcatactct tttatttcgg tatcttatta ttgttacatg cccatttatt
     7861 tggcaaactc catactgggg aaccaaatat catggggacg acatgggatt tgttagccag
     7921 tgatataaaa caaagtcaag tagacaataa cgttggtggt gggatgattg gagcaatcct
     7981 ttatcatttt acttacttct tgattgcaca gcctggaagt tatttagcag cagtgctatt
     8041 actggcagga ggagcattcc tgttcagtaa tctggaaggc tatcagctgt taaatggtat
     8101 ccaatcaatt ggagaacgag tacaggaatt attggaaggt gatcctgcca agcaagctcg
     8161 aaagcaagcg gcaaaggaag agagaatgaa acagcgcgca gaagcgaaag aagcaaggcg
     8221 cttagctgca aaagaagctg cagaaaaaga agctgcagaa tatgagaaga aaaaagcggt
     8281 gagccagcaa agggaaaata ctgctgatga atggcaggaa ccagaaaata cagagccgga
     8341 gcagctaagt tttgttccaa tcgacagttt tcaagaaaat atccatcctg cgaatctaga
     8401 gaaaccagta ccagatacac caaaacagac caatacagca gaaggttttt cagatgagtt
     8461 gccagaggat gacggtacct cattagaatt tgagattgaa gcagaacagg aaaatcaaga
     8521 ctatgaatta ccgacagttg atttgcttga ttctatacca actgtggatc aaagtgatga
     8581 gtataaaaaa attgaaaaaa atatcggcgt attagaacaa actttccaaa gtttcggtgt
     8641 cgatgccaag gtcgtcaaag ccagcttagg accatccgtc acaaaattcg aagtccagcc
     8701 ggctgtaggg gtaaaagtaa gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt
     8761 agcggcgaaa gatgtccgga tggaagcacc gattccaggt aaatcactga ttggtattga
     8821 agtaccaaat ggaaagatca gtatggtttc ctttagagaa atcatcgaag cacaaccaaa
     8881 ccacccagat aaattactag aagtaccttt aggacgtgat gtttctggac gggtacaaac
     8941 ggctgatctt tcgaagatgc ctcacttact cgtggctggt tcgactggta gtgggaagtc
     9001 agtagcaatt aatgggatta tcacaagtat attaatgcgt gctaagcccc atgaagtaaa
     9061 actgatgatg atcgatccga aaatggttga attgaatatg tacaacggca tacctcatct
     9121 gttgacgccg gtcgtgacga accctagaaa agcagcgcaa gccttacaaa aagtagtaca
     9181 agaaatggaa gaacgatatg aaaaattcgc ggcaaccgga gtaagaaata tttctggtta
     9241 caatgaattt gttcaacaga aaaacttgga aaacggaacg aaacatccaa ccttaccatt
     9301 catcgtagtg atcgtagatg aattagctga tttgatgatg gtagccagca atgaagttga
     9361 agatgcgatt attcgtttag cgcaaatggc tcgggcagcg gggattcata tgatcctagc
     9421 tactcaacgt ccaagtgtgg atgttatcac aggaatcatc aaagcaaatg taccttccag
     9481 aatggcattt gcggtatcaa gcggtacaga ttctcggacg atcattgatt ctaatggggc
     9541 agaaaagctc ttagggcgag gagatatgct attcttgcca atgggtgaga ataaaccgat
     9601 ccgtgtgcaa ggagcattca tttctgacca cgaagtagaa cgggtcgttc aatttgttac
     9661 agatcagcaa gaagctcatt atgaagagaa aatgatgccg acagatgaag ttgaaacgac
     9721 aggtgctcca gaacagccac aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga
     9781 aatgcaaacg gcaagtattt cccttctcca aagaagattt cggatcggtt acaaccgagc
     9841 agcacgttta gtagatgaac tggaagctca tggagttgtt ggcccgtcag aaggaagcaa
     9901 gcctcggaaa gtattcattg agcaggaaga aacatcagaa acgttgccgg acgataatga
     9961 catgtaaaac ttgtgtgatg aagggttgaa aaacgaataa ccaataaaaa gacaaggcat
    10021 gatgatacca aaagaaaaaa tggttttttt ccatcttttc taatacggta tgatgtcttg
    10081 tctttttagt ttttgtgaga ttaaagttct attcgattta tttgtgaagt attgcattaa
    10141 ggaaatgaat catgtatagt atgtagcgaa actttgagaa aaagagggaa aatactttgg
    10201 aaaaacagtc catttatggc ttgacgaatg aagaattaat caattggttt atagaaaacg
    10261 gcgagaaaaa attccgagct gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta
    10321 atttcacaga aatgacgaat ctatcgaaac aattgatcga aaaattatcg gagcatttta
    10381 tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt
    10441 tgtttgaact ccctgataaa aacatgattg agactgtact gatgagacaa gaatatggct
    10501 tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg
    10561 ggctgctcaa aaagaaccgt gatctgactg ctggagaaat tgttgcacag atcatgatgg
    10621 tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg
    10681 ggatcggtga gccatttgat aattacgaca atgtaatgga ctttttgcat atcatcaatg
    10741 atgccaaagg attggcaatt ggtgctcggc acattacagt ttccactagt ggattagcac
    10801 acaaaatcaa ggaattcgct aataacggct tgcaagtcaa tctggctatt tccttgcacg
    10861 cgccgaataa tgaggtgcga acatcgatca tgcggatcaa ccgaagtttc ccaattgaga
    10921 aattgatgga agctgtggat gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat
    10981 atatcatgtt gaatcaagta aatgatagac cagagcatgc gcaacaatta gcagatctat
    11041 taaaagataa gaaaaaatta gcatatgtca acttgattcc atataatcca gtcagtgaac
    11101 atgatcaata ttctcgcagt ccaaaagctg atgtattgag attttatgat gtattgaaga
    11161 aaaacggcgt aaactgtgtg atacgtaaag aacatggtac agatattgat gcagcttgcg
    11221 gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt
    11281 ttttcaatta ccataaaagg agcagttttc ttaattaagg aactgttcaa cttaaataag
    11341 agaaaagatt ctatagcgaa agctataaag ctttttttga caagaaaaac cctcatcaag
    11401 caaagaaatg tcctcaattt gatgacagcc tgcttgatgg gggttttagc aattatttaa
    11461 ctgattttct tatatccttg ctggctttct tgtgtagcat gataagtttc tacgtcaaga
    11521 atggcctgtt taaatttttc tcgggtgatt tcataaggca catgtttaat atcatttgtt
    11581 gccatggctt tatctaagat tgcttctaaa tcggtcgtga cattgagatt catgtcggtt
    11641 aacgatactg gaagttggtt ctttttcata aacacataga ttttatcaaa caaatcgaac
    11701 tgctgatcca tcatcaataa ggtcagtaca ccataactga cagatgctcc gtgaaggtat
    11761 ccctccattt tttctagaac agtcgtaccg taatagaatg agtgtgccat agcagaatta
    11821 tagttattgt taactaaaac agaaaccaat ccggtagtaa caatgatatc cgaaacgact
    11881 tgttcaattg catatgaggg acgatcgtcg gcactatctt tcaatgcttg cgtaccataa
    11941 gtcaagagac gatcaatgca catttttccg atttggattc ctaatctatc cgtgtagcct
    12001 agatcatcgc cacgagcaga aaaagtagat tcgacttctt tggataaagc atcgccaata
    12061 cctgcccata agtatttatc aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt
    12121 acaggtggtt ttgaaggaaa gaagagtccg tccattacgc cttcttcgtt atagatgaca
    12181 cataccgcag tgacgggcga acagttcgaa ccaatagtgg gaaaggtgaa gactggttta
    12241 gctagttttt caccaatgac ttttacagta tcgcaagcac ggccaccacc gactgcaaac
    12301 aggacgtctg ctttttggac actttcatgc tggatcaact gttcaatatt tccataagtt
    12361 gaattacccc cgtaccagag actggcgaca acctctattt cctgtgtcaa agctactttt
    12421 attttgtttt ctgcctttga aagtgcagtc ttccctccaa tcagcactac ttttgtccca
    12481 tattctttga cgattccatt tgctttttca tacgcatctg ttccaatggt ataatttggt
    12541 aagaaaacac tttgactcat attcatttcc ttctttcttc gttgaaacgg gttaaaattt
    12601 taaagagtga tcgatctgac tgcggctgta gatggagtag aggtgaacct aagacaggat
    12661 aagtgatgaa taaggtggca tgaacacctt gaaatcatca ataagtatcc taaaaacgaa
    12721 caagtacaaa aacattgaaa acgacaataa tgaatttttg ttcctcttag tatttctacc
    12781 gattcccttt gcttttttgt aattatctaa aaattctaaa aattaagatt attatatgaa
    12841 aacaggtttt atttgtcaat tcataattgg ttttttttaa agcaaaagat aatctatatc
    12901 atgatgaaca aacagagttt tttcctccaa ttgatggctt tcctgatctt tcctattttg
    12961 aataaagtgt ttctgtataa tttttttatt ttataagtaa gataaataat gaaagaatag
    13021 agatactgat tggtagctaa agatttttga gcgagaacat ttcgtttttt caaaaggact
    13081 gttagaataa gcaagaacaa gggggaagac gtatgataat cagtgaattt gaccgtaata
    13141 atccagtatt gaaagatcag ctttctgatt tactgagact gacttggccg gaagaatatg
    13201 gagacagctc ggcagaagaa gtagaagaaa tgatgaatcc agaacgaatc gcggtagcag
    13261 cggtagacca agatgagtta gtaggattta ttggtgcaat ccctcaatac ggtatcacag
    13321 gttgggaatt gcatccatta gttgtagaaa gctcccgacg aaagaaccaa ataggtactc
    13381 gattagtcaa ttacttagaa aaagaagtag cttccagagg aggaatcacg atttatttag
    13441 gtacggatga tttagaccat ggaacaacgt taagtcaaac ggacctgtat gagcatacat
    13501 ttgataaagt ggcttccatc cagaaccttc gtgaacatcc gtatgaattc tatgaaaaat
    13561 taggttataa aatcgtaggt gtcttaccaa atgcaaatgg ctgggacaaa ccggatattt
    13621 ggatggcaaa aacgattatt cctcgaccaa attctcaata ataaaaagag gttgtgacag
    13681 aagtaatcag cttcaagaaa taagaaggaa tttacgaaaa ttacttcttg aatttttgtg
    13741 aaattccaac ttatttccga agaagctact tttggaacac cgtgtaccag aggttgtgaa
    13801 aaagtcgctt agtttcgagt agtaagaaaa attttgtgaa aatggctttc tacatttttg
    13861 cataaatttg gcttaatacc gagaaactgg cttttgaaca ccgtttattc agataaggga
    13921 ctgtgacaag acttttgtca cagtttcttt ttgtttattc ttttttatct ttgtatggca
    13981 ataatagaca atataacgaa aattatttaa tggcttttgg aagaccatgg aaaaccttgt
    14041 acaaagctat tttttctgaa aaattccttg aaacctcacg aaaaaatcat tattttatga
    14101 aaaagacaaa aaaagtgttg attttttaat aattattcat taaactctta aacaacttca
    14161 gaaaatatta attattctga aaattccaat aaaggggtac gtaaaatgaa aaagaaattt
    14221 acatttggtt tggttgcggt atgcggcctt gtacttgctg gatgttatgg cggcagttca
    14281 gccacaagca gtagttcagc aaaaagcggt tcagcagatg gaggaggcgt atttaactta
    14341 gtcgtgcctc aagaaatgcc tacagctgac ttatcagttg caacagatac aatcagtttt
    14401 acagcattga ataacgttta tgaaggaatt taccgtcttg atgaagacag caaaccacag
    14461 ccggcaggag ctagcgagtt ggcagaagtc agtgaagacg gattaactta caaaatcaaa
    14521 ttacgagaag acgcaaaatg gtcaaatggt gatcctgtta cagcagcgga ttacgtttat
    14581 ggctggcaac gaacagtaga cccagctaca gcttctgaat atgcttacct gtatgcgcca
    14641 gttgaaaatg cagaagacat tacagctgga aagaaagata aatcagaact agggatcaaa
    14701 gcagttggtg actatgaatt agaaatcaaa ttgacgaaac aaacaccata tttccaatat
    14761 ctgcttgctt tcccatcatt tttcccacaa aaacaatccg tagtggaaga aaatggggat
    14821 gcctatgcat ctgcaagtga taaagctgtt tataatggac cattcacatt agaagatttt
    14881 gatggaccag gaacagatac agaatggact tataagaaaa atgatcatta ctgggacaaa
    14941 gatacagtaa aactttctga aatcaaagtc agtgtagtaa aagaatcttc tactgcattg
    15001 aacttattca aagatggcca agcagatgac gtgatcttgt ctggtgagtt agcacagcaa
    15061 aacgcaaacg atccagctta tacttctgtt aaagaagcgc ggacaagcta tatcgaattc
    15121 aatcaacgtg aaaagaattc accattcaac aatgtgaacc taagaaaagc tatttcttat
    15181 tctatcgatc gtgaagcttt agtaaaacaa gtactaggtg acggatcagt tgtctctaca
    15241 ggattgatcc catcagatat ggtaaaaagt ccaacaacga acgaagactt tgcaaaagaa
    15301 gctggaaaat tagtttctta tgacaaagat aaagcaaaag aatattggga aaaagcgaaa
    15361 aaagaattgg gcgttgattc tttagaattt gatttgatgg cttctgatga tgattcatcg
    15421 aaaaaagtaa tcgaatatgt tcaaaactca atccaagaaa acttggatgg cgtaacagtc
    15481 aaaccaacac ctgttccatt ctctgtacgt cttgaccgct caacttcggg tgattttgac
    15541 gcagtactag gcggatgggc tgctgactat gcagacccaa gcagctttac tgatttgttt
    15601 gtcacaggta attcatacaa ccgtggtcgc tggagcaatg cagaatatga cgaagcagtt
    15661 aaagcagctt catcaacaga cgctggcgat gaacaagccc gttgggatga tttccaaaaa
    15721 gcaatcaaga tcatctctga tgatatgggt gtcgttccgg tgtaccaaaa agcagaaggt
    15781 cacctagtga atgaaaaaat caaaggtatc gttcaccatg cggcaggcgc ttcatgggat
    15841 tacaaatgga catacgttga agaataatcg ttaataccgt gagcatgaga aaaaacgagg
    15901 ctgcggcaaa tgtcgcaacc tcgttctcat attcacttat cctaacaaag aaaaaagcat
    15961 gaaaatagca gaaagagcaa ttagtattcc ggcaatgatc agccaaaagc tgtacatacc
    16021 gtagctggca gacgagagcg aggaaaattc tggttttttc tttcggttcc ttgttcgtgc
    16081 aagatggacc gatcgctgaa aatgatcgaa gaaacccgaa gaaaagaccc ataaaaaacc
    16141 gccgataatc agaaacggca atgaccataa gaatagatca ttagataatt gaatgagtgt
    16201 aaaggaatgg ttgatgagat tttttattaa aataaccaga atcagtagaa aagctactgc
    16261 gtaggggata gatttttttt tcatttgatt gctcctttat ttttggttca ttatctaata
    16321 atgtagcgaa acatctgtca gaagtcaaaa gctaggggga aacattagtg aatagttata
    16381 tcaaatatgt attaaaacgt gtctttttca tgatcatcac gctttggtta attgcaacaa
    16441 tcaccttttt cttgatgcaa ttgctgccgg gcacgccata tacgaatcag gaacgtttga
    16501 gtcctgaaac aatcgagatg ctaaataaac aagtcggttt ggataaacca gttatcgtac
    16561 aatatgggat ttatctttct aatttgcttc aaggagattt tggaatttcc ttccaattta
    16621 aaacccagcc agtcgcacat ttgttagctg gaagaatcgg accatccttg cagttagggt
    16681 tacaggcaat tatctttgga acagtcctag ggacgatttt aggaacgatc tctgccatga
    16741 agcaaaatac atgggcagat acatcttcta cactcgtagc gatattaggt cgttccattc
    16801 caaactttgt atttgctgtt ttattacaat atatctttgc aatcaaatta caagttttgc
    16861 caatcgcaaa atgggatggc tttgtgtaca caatcttacc aacaattgcg ttggccatgt
    16921 cgccgcttgc tgactctgct cggtttatcc gtacggaaat ggtggaagta ctgcatagtg
    16981 attatgtgga attagcaaaa gcaaaaggat tgagccgttg ggaaatcgcc tttaaacatg
    17041 gtcttcgaaa tagtttgatt ccattgatga ctttattagg accgttagct gtagcattga
    17101 tgaccggatc actggtggta gaaaatatct ttgctattcc tggtatcggg gaacaattcg
    17161 ttaagtcaat cacaacaaat gattatccta cgatcatggc tgtaacgatc ctttactcat
    17221 ttatgctgat ttttgttatt ttgatcgtgg atctattgta cggtctagtt gatccaagaa
    17281 ttcgtgtttc agaagggagc cgaggataaa tggaaatgat accaaagcgt tatgaaacag
    17341 ttgcagatat ccctgcggat gaatttcttc cattacaaaa aaataccgaa gaagaacgtg
    17401 aacagattac tgcaccttct ttgaatttta tccaagattc atggcgccgt ttaaagaaaa
    17461 acaaagctgc cgttatttca atggttttac tattggtcat cattttgatc tctgtgatca
    17521 caatctttgt ttctcctcat gatccaactg cccaaaacgt ggcttatatc aatttgcctc
    17581 ctcgtattcc gggaatcaat atcgatggat tgaatggaaa agcaatggtt ggtggtgaac
    17641 ttgttgataa atatgctcaa gcaaacgtcc cttcaaacgt aaatttcttt ttaggaacag
    17701 acggtttggg acgtgatgta ttaagccgct tatttatggg aatgagaatc tcgttgctga
    17761 tcgcatttat tgctgcatta ctagatgtaa cgattggtgt agcttacggg ttggtttctg
    17821 gtttgttagg cggacgtgtc gataacgtga tgcaacgttt tttggaaatc ttatcaggaa
    17881 ttccaaacct cgttgtcatg attttgatgt tggtcgtttt tgaaccagga attttttcaa
    17941 tcgtggctgc tatggccatc acaaactgga taccaatggc acgtatcgtt cgtgcacaaa
    18001 caatgaaatt aaaagatcaa gaatatgttt tagctggatt gacattaggt gaatcaagaa
    18061 tgaaaattgc attcaaacat attttgccga atatctctag tgtcattatt attcaaatga
    18121 tgtttagtat tccatctgct attttcttcg aagccttttt aagctttatc ggtttaggtc
    18181 ttacgcctcc gtcagcttca ttaggaacga tgttgagcga agggtacaag acattcctgt
    18241 atctgcctta tctattatgg attccggcag taactttatc ggttatcatg attggcttta
    18301 acttacttgc tgatggattg cgtgatgcct ttgatcctaa aatgaaagag tgaagacgat
    18361 gacgaaaatt ttagaagtga aagacttaga aatctctttt gatacgtatg ctggaaaggt
    18421 acgagcgatt cgcggtgtca attttcattt gaataaagga gaaacattgg cgatcgttgg
    18481 ggaatctgga agtggaaaat cagtgacgac cagaagcatc atgcgcttgc tgtcaagcaa
    18541 cgccaatata gatgctggtc aaatcctctt taaaggtaac gatatcgttg gaaaatcaga
    18601 aagagagatg caaaaaatcc gtggtaaaga aatagcgatg attttccaag atccaatgac
    18661 ctctttagat ccgacgatgc ccattgggaa gcaagtcgct gagtccctta gaaagcataa
    18721 taaagtttca aaaaaagagg gacaaaaagc tgcattagaa ttgcttaaat tagttggaat
    18781 acccgaagct gagaaacgta tcaacagtta tccgcatcag ttctcaggag gtcagcgtca
    18841 acggatcgtg atcgcgattg cactggtatg ttatccggaa atcctgattg ctgatgaacc
    18901 tacaacagcg cttgatgtga ctattcaagc acagattttg gagctgctga aagaaattca
    18961 gacaaaaatc gatacatcaa ttatctttat cactcatgac cttggtgtag tagcgaatgt
    19021 cgctgatcgt gtcgctgtca tgtatggagg aagaatcgtt gaagttggaa catcggaaga
    19081 aattttctac aacccgcaac atccctatac ttggggactg cttggttcaa tgccgacatt
    19141 agatagtgcg aacgatcgat tgtatgctat tcctggttct ccaccggatt tattgaaccc
    19201 gccaaaagga gacgcattct atccaagaaa tgaattcgcg atgaaaatcg atgcagaaca
    19261 agaaccacca ttttttgaac tatcaaaaac acacaaggca gcaacttggc tacttgctcc
    19321 gcaggcaccc aaagtgacac cgccagaaga aatccaacgt cgctgggcta tctttaaaga
    19381 gaaacaaaaa catacttacg gtcaaggagg aattgctgat gccaaataaa ctacttgaag
    19441 ttaaaggatt gaaacagtat ttcaatgtag gaaaaaagaa tgaagtacat gctgtaaatg
    19501 acatcagctt tcacatttat gaaggagaaa cattcggttt agttggagaa tctggaagcg
    19561 gaaaatccac tactggccgt acgatcattc gcttgaatga acctactgat ggtgagatat
    19621 tattcgacgg tcaagatata acgaagatca aagataaaaa aggtttgacg aaattccggc
    19681 atgatgttca gatgatcttt caagatccat acgcttcgtt gaatcctcgt atgaaagtca
    19741 gagatatcat tgccgaagga attgatgtta atggactagc taaatcatct gaagagcgtg
    19801 caaaaaaagt cgatgatcta ttgagaactg ttggattgaa tccaagccac ggtactcgtt
    19861 atcctcatga attttcaggt gggcaacgcc agcgtattgg tattgcacga gcattggcag
    19921 taaaaccgcg ttttatcatt tgtgatgaac caatttctgc actagatgtg tcgatccaag
    19981 cccaagtggt caatttgttg caagatctcc aaaaagaaca tcaattgacc tatctattta
    20041 ttgcacatga tttgtcgatg gttaaacata ttagtgaccg aatcggtgta atgcataacg
    20101 gcttgttatt agagatggga acaagtgatg aaatctataa tcacggtgtt catccttata
    20161 cagaaagttt gttatctgct attcctctac cagatccaga ccatgagaga aaacgcagaa
    20221 gaatcaaata tcaacctgaa ccagatgacg gacaagtacg tcaacttcgt gaaatcgcac
    20281 cagaacattt tgtctatgca actgagcagg aagtcccata ttacgcaaaa aaactaaaac
    20341 gacaaaagga atctcttctg gttgctaact aggagggaca tagatgctaa aagcttttaa
    20401 attccgtatg tatccgacag aagaacaaaa acagcaattg attcgtactt ttggatgtgc
    20461 tcgatttacc tataaccatt tgctgaaaaa gcggcagaaa agttggcaac aaacaggagt
    20521 agccaatttt tcgctcacac ccgctacatt aaaaaaagaa tacccattct taaaagaagt
    20581 agacagtctt gctttagcaa atgcacagct taatttggat cgggcttttc gcaattattt
    20641 caagggacgt gccagcttcc caaagcttaa aacgaaaaaa agtatgtggc aatcttatac
    20701 gaccaacaac caaacccgta cgatctatct ggaaaatggc tacttaaagt taccaaaaca
    20761 aaaagaacta atcaagataa atcagcatcg gccagttgaa ggatcgattc gctccgctac
    20821 gatttctgct cgatataatg aagaatttta tgtcgcacta ctttgtgatg tttcgccagt
    20881 aaaaaaagaa tctttagcta aatggatcgg gatcgcctat catccgaaga cattgatcca
    20941 aacatctcga cctctagaag taactttacc aaaatttcac cagacagaag aaaagctgca
    21001 acatgcacag cggaaattga atgtgaaagt ccgctccgct caccatagaa agatcaggtt
    21061 agatcaggca agcaattatc agaaacaaaa gagaaaagta atggatcttt atctgaaaca
    21121 aaagaaccag cgagaagatt atcttgaaca attatctggg aaattggtca aacaatatga
    21181 ctacttattt gtagaatctt ttccaaaaga agaggcacat gctgattttt ctattcacga
    21241 ctggcataaa ttaataacaa aattgcgtta taagtcccaa tggtataata aaaaatttct
    21301 tttgatcaat accgacggag cagaagaaag caattccgta agaaagagcc aagtagtaga
    21361 aaaaatgggc agacattcgg ttatcaaggg ataaaaaatg aatgaaactg ataggagcgt
    21421 tagggttagc cttgttaata aaaagtctta atgacttttg tttctaggaa tttttctttt
    21481 gaagaaaagc tcactaatta tgacaaacca ataaaacaat agcagaaaaa gttcgtacga
    21541 gctttttctg ctattgttaa ttttttattc agaaagttta cgaatacatc aaaattctga
    21601 aacaaaaaac gtaactcaca aagagttgtt tttgcgtttt ttcttgaatg attaggtctg
    21661 aatcttttgc tcacaacctt attcatggtg ccccggcttg agctgataga tttttgaagg
    21721 acggccgatt cctacaggac gttcaccgat ctcatcgaaa tattggagca tagctttctt
    21781 aaaattggaa tgatcgatcg ttttataatc gatccctaag aatttagcaa atacttttcg
    21841 agcttccgta atcgtgaaat ctttacctaa aacttgtaga acttgcggct cgtgttccat
    21901 tttattgact acacggttga atgctttcaa gatgatttga ctatggtcaa aagccaaagt
    21961 atctttgcca gaagactctc cagtgactaa atcaagcgag atagccactt ctccgctaga
    22021 taaatggatc ttgttactat gacgttctag tgtgaaccag cgtacttcct tggcatcatc
    22081 tccggcgatt agcggttctt ctccaataaa ggctaagtag ctgactgtga cgacccagcc
    22141 tcgcggatct cgattaggcg tactgaatgt atgcagttgc tcaatatttt cttttgaaat
    22201 aaccacacca gtttcttcct ttgtttctct taagacgctt tctccagttg actcatcctt
    22261 ttggacaaag ccaccaggca atgcccatga atttcgataa ggatgccctt ttctttggat
    22321 caacaaaact ttcagctgat cttcttcttt gttatagcac atcagtacga tatcgacagt
    22381 caaagagggc ttgtcatatt ctggacgttc ctgtttttga taccagttaa gaaattcttc
    22441 ttcacttgct ttatgttcat aatataattt ttcttcttct ttagaagcaa aacggttcat
    22501 ctgaccacct ccattgacag taaaagtact ttttacctta ttgtagcaga ctctgaaaaa
    22561 aaaccaagga tttacttgaa aaatctaggt tatcatttaa atatgaaaaa taaatggaag
    22621 tatgagattg aataaaaaga aaagcagata aaacggcaat actttatacc gctcttcacg
    22681 aatggcaaag aagccacaaa taacgatata tacgtcaatg ataaaacgca aaatccaagc
    22741 tgctgtcata aaactgttca aatgcccatg gaggttaaaa taaccataca tacgaatata
    22801 aaaatagctg aatattaaat gtgctaatga aagaaaagca atactaagtg taaaaaaaag
    22861 atgtttcttc tgcatgattg ttccagtccc ttactaagat agatagtctt tattatacca
    22921 cgtgtgaggg gagaaataaa aagccgtttt ttagtagata tgaaacaaaa caaaaacccg
    22981 catttattca acctattcat ccttttaaag gatagattga acgtagatag aagtcgttta
    23041 tccagtcttt ttcattttga aaaaaagcta acagcatgct ttttttatgg tatactagca
    23101 aggaaacgaa ttcgcatcat gcgataaagg aggaagagcc ccgtggcaga aaaggaaact
    23161 ttttatatca ctacgccaat ctattatcca agcggcaaac ttcatatcgg caactcgtat
    23221 actacgattg catgtgacgc aattgctcgt tataaacggt tgatgggctt tgatgtgttt
    23281 tatctcactg gagtggatga acatggtcaa aaaatcgaaa caaaagcaga agaactaggt
    23341 gtaaaaccgc aagaatatgt agataaaatg gcggctgatg tcaagaaatt atggaaaacg
    23401 cttgatatca gttatgataa attcattcgc acgacagatg attaccataa agcagctgtt
    23461 caaaaaatat ttgatcgttt attagaacag ggagatattt acttaggtga atatgaaggc
    23521 tggtactctg tttctgacga agaattcttt acagaaacac aacttgcaga agtgtacaaa
    23581 gatgacgaag gtaacgtgat cggtggtaaa gcgccaagtg gacacgaagt agaattggta
    23641 aaagaagaat catacttctt ccgcatgagc aaatacgcag accgtctatt ggaatactat
    23701 gaagaacatc ccgaattcat ccagccagaa tctcgtaaaa acgaaatgat caacaacttt
    23761 atcaaaccag gattagagga tcttgcagtt tcacgaacaa cttttacttg gggagtacca
    23821 gtcaagagtg atccgaaaca tgtggtgtat gtatggatcg atgcattatc caattatatt
    23881 actgcactag gatatggctc cgaagatgaa agtctattcg aaaaatactg gcctgcagat
    23941 gttcagatgg tcggtaaaga aatcgttcgc tttcatacga tctattggcc aatcatgctg
    24001 atggcccttg atttgcctct acctaaaaaa gtatttgggc atggctggct attgatgaaa
    24061 gacggaaaaa tgtctaaatc aaaaggaaat gtcgtttatc ctgaaatgct tgtggaacgt
    24121 tatggtttag atgcactccg ttattatttg cttcgtgctg ttccgtttgg gtcagatggt
    24181 gtctttacgc cagaagattt tgtttcccgt gtcaattatg atctggcaaa tgatctaggg
    24241 aacttattga atcgaacgat tgctatgatc aacaaatatt gtgatggact cgttcctgac
    24301 tatgcctcac ttgtcactcc atttgatagt gaactgtcta cgacggctgc taacgttgtc
    24361 ggacgttacc atgatgcaat ggaaaaaatg gaattcaata cagcattggc tgaaatctgg
    24421 gtgctgattt ctcgtgcaaa caaatacatt gatgaaacag aaccatgggt attagcaaaa
    24481 gacgaagaaa agaaagctga attgaatagt gtcatgatcc atttagctga atctttgcgt
    24541 atcgcagcga tattacttca gccaatcatg acagaaacgc cagagaagat cttcaatcaa
    24601 ctaggattgg actctgaaac aatgaatctt gaaggattac actttggcga atttccttca
    24661 ggaacaaaag tagttgcaaa aggtacacca atcttcccac gtttagatat ggaagaagaa
    24721 gttgctttta ttcaagaaaa aatgtctgaa ggtactcaaa caaacgaaga tacagtcaaa
    24781 tgggatccag aagaaacaga acttgtttca acgaaagaaa aacaaatcaa atttgatgta
    24841 tttgaaaaag tagaactaaa agtagcagaa gtcatcaact gtcaaaaagt agaaggggca
    24901 gataagttgc tgcaattccg actagatgct ggagacagcc aagaccgtca aatcttgtca
    24961 ggaatcgctg aattttatcc tgatccaagc gaattgatcg ggaaaaaagt cgtcattgta
    25021 gcaaatctga aaccacgaaa gatgcgtgga caaatcagtc aaggaatgat cctttctgca
    25081 gaagcaccag atggctcttt acaagtaatc gaagcaccaa aatccatgcc aaatggctca
    25141 gaaatcgcat agaaattcaa agggggtatg acactagttg tgtcataccc cctttttccg
    25201 aaatttgaga agcaattttc gtaaattcct tcttattact tgaagccaat catataatac
    25261 agaaacagag aactatccaa aataaatcct agaaaaagaa gtacgagctt cgctgatttt
    25321 tgttaattta gaataatact aataggaatc gtaaaaacag aaaaaaagca taatgataaa
    25381 gggtcgggca gattttaatt gattcatctg gtactctttt ttattgtcct tacattcata
    25441 aagtttgaat gcaatgactt tattacatct atatttatat ctaacagtag cgttgatgtg
    25501 ttaattataa gttctatcac tttatgttca attagtttgt gctcttatat gtgtgattga
    25561 aaatatagat aaaaaaacaa tcatcggctt tgacttcgat gattgttttc tttattttgt
    25621 aaaaatccta tcacttgatt ttatggtaac cttttatttt tgtcttcaaa cggcttggta
    25681 agagagcagt aagcagtgca aatgggatcg aaaagacata ccagaaaatc gtacgtccga
    25741 taccataatg ttgatagagc tttgtcaaca tcacgtgtaa caagatcaac cctaaaagca
    25801 aggagccagc tataaaccaa tgattatccc aatgcatgac ttcactaagt gccatcactc
    25861 caaaaggata gaaataaaaa tagatcccga ctaaggtcat ccgccagttc tttgtaaatg
    25921 ttccgatatt caataaaaag aaaatcgctg aaagcaaaat accgataggc ggaaaaagcc
    25981 caaccaaaaa ggaatacaac atcccccaca agatcatcac aggacctttg atcaatgcaa
    26041 cgattgcgat gaacaaagtc agcaatatta gtttttgtga taacgttgca acagtcatta
    26101 atccaaataa aattaatgtg aaccaatgcc aatgggactg ctgttgttct ttacgggaaa
    26161 aatcgacccg gttggataaa taatctgcta atttcggata agaacgctta aaatccataa
    26221 actgttcctc cttcgtggaa aaggtaggtt tagtatacga aaaataaaaa agaaatacat
    26281 ccgtcttaag agggagtttt tcactgaaag tggagaaaaa agaatggtaa attaaaatat
    26341 tctcagttat actgaaaatt ataccaaatt tcaaagaaga aagaggatgg gaatgaaagg
    26401 caaactaaaa cgagaaatca atctgtttgg cgcattagct accgttatgg gaaccgtgat
    26461 cggtgcaggc gtcttcttca aaactgctgc tgttactgct agtactcagt ctacaagttt
    26521 gacattgcta gcttggcttt tgggtggttt cttaacgatc tgtgctggat tgacagtggc
    26581 tgaattagct acagcaatcc cggaaactgg tggagctgta aaatatattg aagctgcgta
    26641 tggaaaattg cccagctttt tattaggatg ggcgcaaagc ttgatttact ttcctgctaa
    26701 tattgctgca ttatcgatta tctttgcgac acaattgacg aacttattac aattatctac
    26761 cgattatctt ttgttgattg cagtgatcac cgctgtttct gtgacagggt tgaatttgtt
    26821 agggacaaaa gtcggtgctt ctgtacaatc agtgacgttg attgttaaat taataccaat
    26881 tgctgtgatt gtcatatggg gattattgac cccaggacaa ggaactgtcc agttatttcc
    26941 aatcgaagct ggaaaagatg ttacttttgt cgaaggattg agcagtgcgt tgttagcaac
    27001 gttgtttgct tatgacggct ggttaggtgt cggtgcaatg gcaggggaaa tgaaacggcc
    27061 ggaaaaagat ttgcctaaag caattattct tggtttgagt tttgtaacag tcgtttatct
    27121 attgatcaat tttgtttttt tgaaaacttt gccgattgat catcttgccg gtaatttgaa
    27181 tgcagcttct gaagcatcag acgtcatttt tggaggaatc ggtggaaagc tggtcactat
    27241 tgggatcttg atctcggtat acggtgcatt gaacggttat acactaactg ggatccgcgt
    27301 gccttatgcg atggctttag aagacgagct acctttcagt aaacagctga caaagctttc
    27361 aaagaagttt acggttcctt atgttcctgc ggttttccag ttagcagtag cttgtattat
    27421 gatgagcctt ggttctttcg actttttaac agacatgttg atttttgtga tgtggctatt
    27481 cagtttactg atttttatcg gtgtctttat tttaagaaaa aaagcgccgg aattgccacg
    27541 tccatataaa gtaccacttt atccaatcgt tccgattatt gcgattctcg gtgctatttt
    27601 cattttaggt atgacgatga tgacgcaaac gaaattagca ttgatcggta taggtgttac
    27661 cttgataggt atcccagtct attatcaaaa aaagaaaaaa cgctcagaag agtaaaatat
    27721 ttcaacaaca gacagaaaaa gtacgaacta ggtcctctag atcttcgtgc tttttctatt
    27781 tcaataaaac aagttcttct attttgattt ttgctacttc tgcaagtagt gcttatgtgc
    27841 taaagtaaga atgaaaagga gagataaaca tgatatttga ttctcatacc catttaaatg
    27901 ctgaacagtt caatgaagat attccagaaa cgattcagcg agcacaagaa atgggggtaa
    27961 cgaaaatggc ggtcgtgggc ttcgatacgc caacgattga aaagtctttg caattaagcc
    28021 atgactatcc aaatatatac agtattatcg gctggcatcc gacagaggct ggcagttata
    28081 cgaaagaaat cgaaaataaa ttacaagaac aattgacttt accaaaggtt gtagcattag
    28141 gggaaattgg cttggattat cattggatgg aagacccgaa agaagtccaa gataaagtat
    28201 ttcgcagaca gattgctatc gcaaaagaaa tgaacctacc aatcagtatt catactagag
    28261 aagcacttga agacacgtat caaatcctaa aagaagaaga tgttcgagat atcggtggaa
    28321 tcatgcatag tttcagtggt gattatgaat gggcaaaacg atttcttgac ttagggatgc
    28381 atatttcatt tagcggtgtc gtcactttca aaaaagcatt agacgtccaa gaggctgcag
    28441 caaatgtacc aatcgaacga ttacttgtgg aaacagatgc cccttatctg gcaccagttc
    28501 cttttagagg aaagcgaaat gaaccaggct atactcgtta tacagtagaa aagattgctg
    28561 aacttcggaa tcttccgaca gaagaagtgg ctgcccaaac atggacaaat gcgcaccgat
    28621 tatttggtct aagcgaacat ggataagatg aagatccaag agattatagt cgttgaagga
    28681 aaagacgata caagaaggct gcgggaagta gttgatgcag atacgataga aacaataggg
    28741 tctgcaatca atgaagagat cctgatgcaa attgaacatg cccaagagac tcgtggagtg
    28801 atcgttttta ccgatcctga tttttcagga gaaaaaataa gaaaaatcat tatggaagct
    28861 gttcctcagg caaaacatgc ttttttgccg cgcacacaag ctaaaccaaa gaaaaaggga
    28921 agccttggtg tcgagcatgc aagtgatgct gctattttag aagcattgaa aaaggtcgtg
    28981 acgccagaca tttcccaaac ggctgtttct gaaatcacta gacaagacct tttagactat
    29041 ggtttaatag ctggggcaca agcaaaagaa aaacgagaaa aactaggtga cgagttgcgc
    29101 atcggttaca cgaacggcaa acaattggaa aaacgtttga agatgtttcg tattacgccg
    29161 aaagaactcg cccaagcaat gaaaatagtg gaggaacaac atgagtgaat atcgtgaaat
    29221 tgcgacaccc tctagaacaa aagagatttt attgaaacat ggtttttcat ttaaaaaaag
    29281 tttaggacaa aattttctga ctgaaccaaa tattttaagg aaaatcgtag aaactgcgca
    29341 aatagatgaa catacgaacg tgatcgaagt tggaccagga atcggtgcat tgacggaaca
    29401 attagccaag catgcaaaac aagtcgtagc atttgagatc gatgatcgtt tgatccctgt
    29461 attggctgat acgatgcaac cctatgacaa tgtgactatt gtacatcaag atattttaaa
    29521 gaccgatttg tcaacagctg ttagagaaac atttcatgag gagcttccgt taaaagtcgt
    29581 agcgaattta ccttactata ttacgacacc gatcatgatg cattttcttg aatcagattt
    29641 ggttgtggat gaactagtcg tcatgatgca aaaagaagta gctgatcgta tctctgctga
    29701 accaggaacg aaagcttatg gttcattatc gattgctgtt caatattata tggaagccag
    29761 tttagcattc atcgtaccaa aaacagtatt tgtccctcag ccaaatgtag attcagcgat
    29821 tttgaaactg acaagaagag atataccggc agtcgaagtg acagacgaaa aagcattttt
    29881 ccgattgaca aaagcggcat ttcagcaaag aagaaaaacg ctttggaata acttgcagca
    29941 ttcgtatggc aaagatgacc agacaaaagc atggttagca aaaagcttgg aaacagctgg
    30001 aatcgatcca aaacgtcgtg gggagacttt gtcattacaa gaattcgccg cattaagcaa
    30061 tgcgatgtca gaaaatatgc agtaaaaaaa gaggttgtga cagaagttgt gaaaaagctg
    30121 tcctgcatca agtaataaga acagccaaac aaaaatagtt cctcatgttt ttcgtttgtt
    30181 tgggcttatt accgcagatg caagcttttg aacaccgttt aagaaagagg ttgtgggcct
    30241 gccgtttaac tctaagtcac aaggaacaat ttcaaaaaac agcttctcat gtttttgagt
    30301 tagttggtct tattacttga tgcaagcttt tgaccactat tatgccgaac aaggagatgt
    30361 gacacaaatt ttgtcacatc tcctattttt gtttcttgat caaaaaattc ttatacttga
    30421 tactcacact cattttgtat ggatttagaa aagaatatgt gtcttgacag ttattagtaa
    30481 gtgagttata ctaagtcgac atttatgtgt caagacatat taggagagag aaaaaatgag
    30541 aaaaaattca gttcgaaaac taacgatttc tgctttattg attgggatgg gggtcattat
    30601 cccaatggtc atgcctaaaa tcatgattcc accagcttcc tttactttgg cgtctcatgt
    30661 gccattattt attgcgatgt tttttacacc aggagttgca gtggctgttg cgctaggtac
    30721 gacatttggt ttctttttaa caacgccggt tatcatcgca ttgcgagcat tgtcacatct
    30781 tgtgtttgcg ttgattgggg cttggtactt gcaaaagcat ccgagtatcg ttttaaaaaa
    30841 tggacagttt acttttgcta attggcgttt ccaagggttc aattttgtga tcggtgtgat
    30901 tcattcttta gcagaaatgc tagtagtcag catcttttac tttattggta atatgcctga
    30961 aacatattat tctcaaggat atttttatac agtattcatc ttgatgggga ttggtgggct
    31021 tatccacagt ttagttgatt ataatattgc ttattttata gcaggaacac tcagcaaata
    31081 ttttgatatc cccgtattta cggcagcaaa aaaagaaaat cggaaagagt cgattcaagg
    31141 gtacgcgaag aaaacgacat attagacatg atctctcaaa aaaaaaactc tcatctagta
    31201 atggataata aatcctctaa gatgagagtt ttttgtccta aaaagagctg caccaacatc
    31261 ttctggcaca gctctaacag ggggcaattt atggaagttt gatgacttgt tctgtttctt
    31321 tatcaaagaa gtggcctttg ctgatgttga aggcaaggtc gactatttcg cctggtttat
    31381 ggaaatctct tgcatctact tttgagatga actcagtaga accagttttt gtgtaaagca
    31441 tcgtttcagc tccaagtaat tcggaaacga caacttctga tttcactacg gcttcaggtg
    31501 aagcttcaag ggctacttgt tcactgtgga tgtcttctgg acgaataccg aagataactt
    31561 cttttccttc ataacctttt tcaactaata ctttgttttt tccttcagga atacgaagct
    31621 taagcccatg tccatctgtg ataacaccat ttttcaatgt cacattaaag aagttcatgg
    31681 caggagatcc aataaagccg gcaacgaaca tattgacggg tgtatcataa acttctttcg
    31741 gtgtaccgat ttgttggata aatccgtctt tcatgataac gattcggtca gccatagtca
    31801 ttgcttctgt ctgatcgtga gtaacataga tggtcgttgt ttcaagacgc tggtgaagtt
    31861 tggcaatctc agcacgcatg gctacacgta atttagcatc taaatttgat aatggctcat
    31921 ccattaagaa gacttttgca tcccgaacga ttgcccgtcc caatgccaca cgttggcgtt
    31981 gtccaccaga taaagcagct ggttttcgtt tcaagtattc tgtcagacct aagatctctg
    32041 ctgcattgtc cacacgtttt ttgatgtctg ctttatcata tttacgtaat ttcaagccaa
    32101 aagccatatt atcaaaaaca gtcatatgag gatacaatgc gtagttttgg aaaaccatgg
    32161 caatatcacg gtctttaggt gccacgtcat tcatgacttt tccgccgata tttagttctc
    32221 cttcagagat atcttccagt cccgcgatca ttcgcaaagt agttgacttt ccacaaccgg
    32281 aaggaccaac aaaaacgata aattcacggt ctttgattga tagattaaaa tcagttacag
    32341 aataattttc tgcattgtca tattttttat atacgttttt cagagccatt tctaccataa
    32401 tacgttccac actttctttt ttagttttat taactattta aagtataaat gaaagcgtta
    32461 actaacttca atgtcatgtt gaacaagaat tttttctttt ttttgtcaat gtgctagttt
    32521 taagctttaa taaatatcca taagaaataa aaactgatac actggagtaa ataagtatgt
    32581 taacaatatc aaaaggagtg tctcttatga aaatcgcttt gatcgctcat gaccgaaaaa
    32641 aacctatgat ggtgaaatta gcaacagcgt ataaaacaat attggaaaaa catgaacttt
    32701 ttgctaccgg gacgactggg cagaggatca cggaagcaac cggcttgccg atccatcggt
    32761 ttaaatccgg accgttaggc ggggatcagc aaattggagc catgatttcg gaggatcagt
    32821 tagatttggt gatttttctt cgagacccgc tggctgcaca gccccatgaa ccagatgtaa
    32881 cagcacttat ccgtttatct gatgtctatg agattccgtt agctacgaat atcggaacag
    32941 ctgaggtgct actaagagga ctggaagccg gcttcctaga ttttcgaaga atcgtccatg
    33001 aaatagacaa gcatccactt tcattttgat ggataagcgt atggaaaaat aacgtttaat
    33061 gttcgcctat atgtagctat aaaagctaaa caaactgata atatgcgata taatacgaac
    33121 gtattggata atataaacaa taatattagt ttttcgtatt tgcagtaaat gtgaaaatat
    33181 gctatagttt ctgtgggaaa agatcccaaa aataatacag agtagaaaat aaagcgttaa
    33241 gtgctaagag gatgggatgt tgcctcttgg acgaaggacg taatgttcgc ggttttattt
    33301 tcgcattcgc tgcatgatac gatgtagcag ctcttaaagg agatgctaaa aatgaagaaa
    33361 caccggttag acgcacgtat gattgctatt atgggcttat tgattgcatt gatggtcact
    33421 ttgtcccgac tggtagcaat cgagacccca tttattaaaa tcagtgtcac atttattcca
    33481 caagtgatca tgggcattct ttttggtcct ttttggtcag ggataggcgc agttttagct
    33541 gatttagtag gaatggccct cttctcgaaa tctgcattct ttattggatt tacattgaat
    33601 gcatttattg aaggagcaat ctacggattc tttttctatc gaaaagagat cacttggaaa
    33661 aatgccattc tggctacgct tagtgtcacg ctgatcatca acttattttt gacaccatta
    33721 tggcttgcgt tgatgtacca tgtgccattg ttcagctggg tcgtttgggc gccccgcctg
    33781 ttaaaaacag taatatggtt accgattcaa tcaattgcca tttattacgt aggacgtagt
    33841 attccttaca aaaaaatttt aagaagttta gcgatccacg ctaaataaaa aacaagcagt
    33901 cttcccatcc cagaagactg cttgttttta ttgtgctgtg aattgtgctt gatagagccg
    33961 tcggtaataa ccatcttttt gaagcagctc atcatgggtg cccatttcga caatagctcc
    34021 ctgatccatc actaatatct ggtccgcatt tttgattgtg gacaggcgat gggcaatcac
    34081 aaaactggtt tttccttcca tcattgctaa gaaggcttgt tggatttttt tctctgtcaa
    34141 tgtatcgact gagctggtag cttcatctaa gatcaacata gggggattac tgatcatcgt
    34201 tcgagcaatc gtcaacagtt ggcgttgtcc atctgatatc tttaaccctt gaccgccaat
    34261 cttagtatct aatttttccg gcaaacgttc tacaaattca tacatataag aggcttttag
    34321 ggcatcattg atttctgcgt cacttgcttc cggattccca aaacgaagat tttctcgcaa
    34381 tgtactgtca aatagccaag tatcttgtaa caccattcca aaacttttac gtaatgtatc
    34441 acgttggata gagcggatgt catggtcatc gactgtaatt gttccttttg ttgtgtcata
    34501 aaaacgcatc agcaaattaa caagtgtgga ttttccggcc cctgtttttc ctactatagc
    34561 aatggtttga cctggataag cagtaaaatt gaaatcttcg atcaaacgct gcttggggtc
    34621 ataagaaaaa gaaacatgat caaaagagac ttttcctttg atatttttgg gttccaaggc
    34681 ataggcatct ggcaaatcag gcttttcttc tggctgatcg atcaaatcaa atgctcgttc
    34741 tagaccagaa aaagcggttt gcagttgtgt cgtgattcca gaaagttcga taaatggttt
    34801 agaaaactga cttgagtaga tcgtaaagct ggaaatcaca ccaacagtga ttgacgaacc
    34861 actcttcaat gccaataggc cgccaactaa accaatcgat aaataagcaa ggtgatctac
    34921 aaaacgagaa gacgggtttg tcaaggaaga agaaaattgt gcccgttgtc ctttttcata
    34981 tagatcagca tttagcagtt caaattgctg ttgactagct tcttcttgct gaaaagcttt
    35041 cacgattttc tggttaccga ttcgttcggt cacaaagccc gagatatccc caataatcct
    35101 ttgctgtcta tcgaaatttg tttgtgaagc acgagcaacg atccaactca caaggaaaat
    35161 aattggtgta gaacaaagaa cgaccaatgt cagaagtgga cttagacgca tcataaaaat
    35221 aaacgaaaga atgatgattg ccactccaga aaataattga ttgaaggccg cagaaattgc
    35281 aatggaaata ttgtccatat catttgtaaa tcgactgacg atatttccgt gggagttttg
    35341 atcataataa cgaagtggca atcgattcag atgagcaaat gcatcttttc ttaattttgc
    35401 aacggataag taagctaacc gattgcttaa cacttggatg agccattgac tgactacgtt
    35461 gattaaaacg ataccaccga atagaataag taaatggaac agtcgattga agcggacctg
    35521 tccttctcca atcatttgat cgatactttg accaatttgt aacgtcatca caactgttgc
    35581 aatcccattg atgattccta gtatcacagc tagccaaatg tcttttgcat aggcagtaag
    35641 gtaaggaatg aatcggcgga gcgtctgcaa ggataatttt tttactttca taactattct
    35701 tcctcctgtg atgcgacgat ttcctgatat tctgctgatt gagcaagtaa ttcttcatgg
    35761 gtaccctgag cagcaatctt accttgatcc atcactaaga tatgatgtgc ttcttgaata
    35821 gagcggacac gttgggagat aataatcact gtactgccaa gataagtctg tagcgcctta
    35881 cgcaaatcca agtctgtttg ataatccaac gcacttaaag agtcatctaa aatcagtaat
    35941 gctggcttgg caatcaaagc tcttgcaatc gtcagtcgct gtttttgtcc gccagagaaa
    36001 tttttcccat tttccatgac ttttgtatct aaaccatttg gaagctgacg gacaaattct
    36061 tctgcctgag cgattttcag agcttcccaa cattcttttt ctgtggcgtc tttcttaccc
    36121 cattgaaggt tttcacgaat agtcccggta aatagtacag aagtttgggg aacaagagca
    36181 atttgctgac ggagatgatc cagctgccaa gaacgaacat ccattccgtc cattataact
    36241 gtaccggaac tgacatcata gaaacgcgga atcaattgtg tcaaagtcgt tttcccgctt
    36301 ccggttggac caatgattcc aaggactgta tttcgcttca gctgaaatgt aatattttgg
    36361 agagaaagac cagaatcagg agtataacgg aagtcaacat ggtcaaaagc gataattgct
    36421 tcagaagaaa aatcgggagt agtactgacc tcagcttcaa gaatcgaatt ttctgtgtct
    36481 agcacctctt tcacccgatt tcctgaagct tcggcacgtg tgaagatcac gacgaggttt
    36541 gaaacaacga tcagtgccaa aagcatttga ttcatataat tgatcaaagc aagaacttgt
    36601 ccttgttgca agctaccaat atttactttg atcccgccaa ctgtcagcaa acagatgatc
    36661 ccgacattca tgatcaaggt tgtagcaggt gataataggg cagagatatt ggaaacacgt
    36721 aaataattgt tcgctagatc atttgtgctt ttatcgaact tctctgtttc tttttttgtc
    36781 tgcgcaaatg cgcggatgac acgaacaccg ctaagattct gactaacgtg ttcattgagc
    36841 tgatctagtt tttcttgcac tttttggtag agaggaacgg tttttttgat gataaaaaat
    36901 aaaatgattg agaaaatagg caataatgct aagaaaaaca gacctacttc ccagtcgatc
    36961 acaaaagcca tgaccactga cccgatactt aaaaacggtg ctctgatcaa taaacgaatg
    37021 accattgcta aagctagctg aagctgattg atgtcgtttg tcattcgggt gatcaaggta
    37081 tctgttccaa aatgattcaa ctcgttgtga gagaaagtat tgattttttt gattagctga
    37141 ttacgtaact ctgtaccaaa tccttgtgaa gctactgaag catagtattg gcaaatgata
    37201 gcacaaatca gaccaatcac agacatagcg accatccata agcccatttc aatgattttt
    37261 cctcggtcat tcatttttag tccattatcg atcaaggaag ccatcattaa aggcaggaca
    37321 agttcgaaga cagcttcaag aaatttgaag aacgggccca aaatgatttg cttacgatag
    37381 tcttttgcat aacgtaataa ctgaatcata tgattcctcc tattatttat ttgtccacaa
    37441 ttgaaaaaac aagtactacc acattgtagc ttaggaaatt tagaatgaaa agagaacaag
    37501 ccttttcata aatgaaagtt ttattatgaa gaagctttag aaattgaata gactattttt
    37561 tttaaaaaaa agaaaatgag aaaacatgcc agtctcttca ttcataggaa cgtctatttt
    37621 acttaatttt tctataaatg aattctgcat aaaaaatata tcaagtaaat gtttatagat
    37681 gaaactctat ttacttcttt tttaatttgt tcttgcaatc ttttttgcta cgtaattttt
    37741 gtaaaaaagt gggttgagag aaatctaatt gattttcaaa gaaggagtat gaaaatgaga
    37801 aaaatattta ttcgtttatt gtgggtacta tcttagagga ataaataata gtggagaaaa
    37861 ctatggtttg gcgcagattc tatcaggttt gatggaacga agacaacctc ccgacatcaa
    37921 gtcaaaagct acttgagatt ttgatctgaa aataaaaaaa gaaaacaagg taggaacatc
    37981 aatgtttcta ccttgttttc gtaatcaatg ggaaaaaact aagagtggtg tacgtaatca
    38041 ataaaaagga tggtgacaac agtacctctt tactctctga aagcatcata actcgttttt
    38101 cctcattatg ccaataaatt gttgttatac cacatataag gatttgtaat agctaaaaac
    38161 agacaggaaa gttgaaatct gtgaatctta ttttgtatgg aaggatttat agaacgcaaa
    38221 aatcaagata aagatgaata aaaatcctgt ttcggctata tattgcgtat ctacgccaat
    38281 aaaacgagtt tgttctgtca tagccatata aagcaaaggc aaaaatacaa ctacagcgag
    38341 ataagatccg atgatttctc gaaaagtttt ccaggaagta tgtttcctgt ttttatattt
    38401 atccgatttc attgaatagt catagcctcc ttattctttc atatgttgaa attccagtat
    38461 aaaaactgga aggaactgta cgttttttag aataaaaatt ataagggata agtaggctgc
    38521 tgtctataat aagatatatt tttcaattct ttattaaaga ttttattgac aaaatgaatc
    38581 cgttttctat gatggaggag gggtgaataa gttgttgaag aaggaaattt tatgttactt
    38641 agagaaccag acagcctttt tcgatttaga acatatgaac gaggtcttta cagcacaaag
    38701 gttagctgat cattttgggg taaaaagaaa cacagtcagt cattatttga accagttaaa
    38761 tgatgagcaa ctactagtca aaatcaattc tcgaccagtg atttatttcc acaaagaagc
    38821 ttttgaaaaa caatttttta agttacgcac gaatttttat ttttctatcg atgatctcaa
    38881 agaggaacag ccttttttcg cgcaaccaaa agacttattc tcttttatga tcggatacga
    38941 cgccagtttg aaagaaagta tcgaacaaat caaaacagct ctttactatc cagatggcgg
    39001 attaccactt ttgattacag gcgaaagtgg cacaggtaaa agttatttag ttaatttggt
    39061 ctatcagtat tgtctgcttc atgatctgct agaagattct gcaccattca tcacttttaa
    39121 ttgtgcacaa tatgcagata atcctgaact tttgactagc aatttgtttg gacatgttaa
    39181 gggagcgtac actggtgcag aagaaaataa aaaaggggct tttgaagcag cagatggtgg
    39241 gatcttgttt ttagacgagg tacatcgctt aacaccagaa ggtcaggaaa aactgttcac
    39301 ctatcttgat caaggtgtga tttatcgtat gggagaacct aatttgtcac gccggatcaa
    39361 aacacgtctc ttttttgcta cgactgaaga gattactagt catttcttaa caactttcat
    39421 tcgaagaata cctatccgaa tcgaactacc tgcacttaat cagcgtagtc gtaatgaacg
    39481 gctagaactg atttactctt tttttctcga agaacaaaga aaaatgggga gccctttgtc
    39541 agtcagtgga ccagctttgt cacttttaac aagtcagaaa ttatccggaa acataggaga
    39601 gctgaaaaat atcgtcaaag tttcagcagc aaaagcatat gctgaacagc gtgaacagcc
    39661 tgaaatccat gtcacgatcc atcatttgca aaaagaacta cttgcgcagc ctattactaa
    39721 aaatacagca cagcaaggaa tctatattac gcaagaccag accttagagc aattaatgga
    39781 gaagcaacag cccgaacagc agcgaatcgt taaaagtttt gagcaaatcc taattgattt
    39841 caagaaaaat aactgtctgc tatattcttg cgaaggaaaa ttaaagcaag aagtgattca
    39901 attatttgat tttttgctgt ttgagaccag tagacaagaa aaacacgagc tgctggttta
    39961 ttggacacaa tctatccgag agacctttcg acaaatggaa actgcctatc aaatcaaatt
    40021 cgatggaaac agtgtctatg ccttgagtta ctatctctat cagcgaagca ctatcaaatg
    40081 gttaccggaa gaacatgata ttatccaact aatcaaagaa ttagaacaac aagtttctca
    40141 gtcttatcca tctagttatc actatgtcca acgaattctg gaattaagta agatcaaatt
    40201 agatattgaa gacacaagta tggatcggat tttactgacg atctatctaa aaaaagcgaa
    40261 atggtcaaaa gaaaaacgac tgccaaaagc gatgattgct gctcacggtt atgcaactgc
    40321 tagcagtatg gcaaatgtag taaatcgttt attacaagag gatctatttg aatcatttga
    40381 tatgccacta gatgtcacac cacagcagat tgcttcagaa atccttgatt attgcgaaaa
    40441 cagcgatgtt tcaaatggat tgatcatatt agtagacatg ggatctctga aagaaatcca
    40501 tcagtttttt aaaaaacagt tatccgtacc gcttttgatt ttgaataatg tgacgacacc
    40561 tttagcaatc acagtagggg aatgcctgca aaaaaatgta tcattagaag agatagcaga
    40621 agagactgtt cgacagatcc agccagaatg gcgactgctc tatccagagg aaaacaaacc
    40681 caaagcactc attactactt gcttcactgg aatcggtacg gcggtccact taagtgaact
    40741 gctagaaaaa agcttaccta cggcttgtca gttgaaaatc atcccatatg aatatcagca
    40801 attaaaagat aagaaaaaca gtgacccatt attttccata tacgaagtcg taggaatgat
    40861 tggcaccaca gatcctgata tcaccaatat cgactatctt tcattagaag acctcatctc
    40921 gggggaaaag atgtctgtac tagctgaatg gttggacact actatgaatg cttcagagaa
    40981 ggaaatattc aatcagcgca tcattcgtaa tttttcattg gaaaaagtac tggattccgt
    41041 gactattcta gatacagaga aggtgatggg agaaatcgat cattttatga gagaattaga
    41101 ggtgcagttg aatcgaagca tcagcaatcc caaaaaatta gcgttgtatg tccatgtgag
    41161 ctgtctcatt gaacgattga tccgacaaat gccaatcgaa acctatcaag gattagagaa
    41221 atggaagcag tgtcaaaaag aagggttatc tgctattaaa tctgcgttta gtgtcattga
    41281 agagcattat agtgtcatga tccccaattc tgagattgcc tatatctatg atattttgag
    41341 tgaagataca gagtttctct cgatagaaga agaattttga acataagcaa gttgttgcca
    41401 ctaattttgg catgcaactt gcttttttag tatgtgtaag tgaaaagagg agatgaaaaa
    41461 gtggatagag aaattatctt agcttcccat ggaaaatttg cttcagggat attagattca
    41521 ttagagctga tctatgggaa aaatcattct attactgtat tcgattgcta tactgatgag
    41581 aattttgatt tagcggaaac agtaaggcag ctttttatga ggtacaaaga taaagaaatc
    41641 attgttctga cggatctttt tggcggaagt gtcaacaacg aattcttaca atatatcaat
    41701 cgggatcatg tctatctcgt tgccggattg aatttgccac tattgattga gctagtatct
    41761 cggttggacg ctgaagtaga gacaactgtt ttgatccagc aggtgctaac tgattcaaaa
    41821 aaaatgatcc agttttgtaa cgagcggctc aatcagaaaa tagaagaaga cgaattttag
    41881 gaggaagaaa aatgattgta ttgacaagag tcgaccatcg gttattacac ggacaagtag
    41941 ctttttcatg gacacaaaca ataggcgcag actgtatttt gattgctaat gatgatgtac
    42001 ctacgaatga gatacgaaag acaacgatca aattagccaa gccacaagga gtcaaactag
    42061 tgatcaaatc aattgatgac tcgattgccg cgttgaaaag cggggtgaca gataaatata
    42121 agttattcat cgtagtggaa tcgatcgagg atgcatataa gctggcagaa gcgtatccag
    42181 aaatcaaaac catcaactta ggagggatca aggcaaaacc tggtactcgc agcatcggaa
    42241 aagcggtaaa tattttacca gaagaggagg aacgcttgaa acgattaatt gacaaacaaa
    42301 tagaagtaga aatccgtcaa gtaccagcag ataaaaaagt ggatgtaaga gaagttttgt
    42361 aagaaaggaa gaacctcaat gattgtacaa gcagtcttat taggaattgt tgcatttgtc
    42421 gcacaatcag aatatgcact agggacatcg ttgctttctc gtccgattgt gacggggctg
    42481 tttacaggaa tcgtgttagg tgatgtaaaa actgggatca ttatgggcgc aactttagag
    42541 ttagcattta tcggatcgtt ctcagtaggt gcttcgattc cacctgatgt tgtgaccggt
    42601 gggattttag ggacggcttt tgctattaca gctggagccg gtacagaaac cgcgctttta
    42661 ctaggtttgc cgattgctac gttgacattg atattgaaaa atatttactt agggcttttg
    42721 attccaatta tgaaccataa agcagacaat tatgcagaag aaggaaatta taaaggagtc
    42781 gagcatatgc acttgcttgc cggtatcggt ctttccttga tgcttggtgt tgtggtaatg
    42841 gtttcttata tggtgggaag caatacgatc ggaaatctat taaatatgat tcctgacttc
    42901 gttcaaaagg ggttgtcagt agctacaggg ttgattccag ctcttggttt tgcgatgctt
    42961 gctcgtttgc tgatcaacaa acaagttgca ccatattttt tcttaggttt tgctatagct
    43021 tcttacttag agattcctgt gaccggagta gctatttttg gtgcgatttt agcagttgtg
    43081 gtagtcaata ttatgaatgt ccgtcaacta ccacttcaaa caactgcagg ggaggtagaa
    43141 gaagatgaag aattctgaga tcaaaaacag caaaataacg aaaaaagagc taaatcacgt
    43201 attttggcgt tcttttcaaa tggagttttc ttggaattat gaacgtcaga tgaatatggc
    43261 ttatgtttat gcaatgattc cgattttgaa aaagttatat cagtcgaaag aagaaatggc
    43321 agcagctttg aaacggcatc tagagttttt taacacgacc ccacatatcg ttacactgat
    43381 tttaggaatc acggctgcaa tggaggaaga aaataaggat gatcctgaat ttgatgtgac
    43441 tgcgatcgat agtatcaaaa catctttgat gggacctctt gcagggttag gagattcttt
    43501 cttttgggga actttgcgat tgattgccac aggtgtgggt acctctttag ccatgcaagg
    43561 aaatatttta ggccctatct tgttcatttt gattttcaat attccgcaca ttctgtttcg
    43621 ctatctagca acaggttggg gatatcgctt aggaacgggt tttttgaaaa agatccaggc
    43681 aaacggtatg atggaaagtt tgacattagg cgcgtctatt attggactga tggtcgttgg
    43741 agcaatgact gccacgatga tcaccatcaa tattccttta aaaatcggtt caggagaaaa
    43801 tgctgtgact gttcaaagta tttttgatga tatcgttcca aatatcttat gtcttggagc
    43861 atttggcata gtgttttatc tattgaagaa agaagtgaaa ccattaacga tcttgatcgg
    43921 actagctttc tttggaattt ttggttcgtg gatagggatt ttttaaaaaa ggagcagaga
    43981 aaatgtttac gatgcaagat tatatctatg aagaaaagga agtactaagt acgatcttga
    44041 aaaagaatga tttttcgaca agagaacata tgaaaaaaac agtgaattta ctgatcttag
    44101 caacgggttc atcttataac gcttgtttag cagcgaagcc agcattggaa tcttatggtg
    44161 atcttactgt cgatattcaa gaaccttttt attttttcaa ttatggaaaa ctttctcctt
    44221 caatcgatac tgtgattgct gtgtcacaaa gcgggaaaag tgcttctact gttgaagcag
    44281 taaaaatgat acaaaaacaa gggttacctg ttgttgctat cacaaatgac gtgcaaagtc
    44341 cacttgcttt agaagctgca caaattattg atttaggtgc cggggtagaa tcagtaggct
    44401 tcgttacaaa aggctattct gcgactgttt tacagttact actcttaggg ataggaattg
    44461 gaataagtaa aaataaaatc agcaaaaaaa tagaacaaga ctacatgcaa cagttgcgca
    44521 aaataatcaa ccatttacca gcgattattc aaaaaacgga agaatttttt gatggatatc
    44581 aaagtttatt tcgtttagca cagcgtttcg tcaccattgg atatggtcca aactggggaa
    44641 cagctaaaga agcagagacg aaattgactg aaacaatccg cgttccgtca caaggatttg
    44701 agttagaagc ttatatgcac ggcccatacc tggaggcaga tgcttcgcat ttgctattct
    44761 ttattgaagg ggaaagtgta aataaggaac gttcgcaaaa gttgcaaaga tatatgagtc
    44821 ggtacgttgg agagactctc accattacca caaaaaaagc aagaaacgag aaaacacttg
    44881 gattagcaat agaatgtgat gaatatctgt ctgtattagc gcttgtcgtt ccgtttcaac
    44941 tattcgctta taaaaccgca gtagctaaag gtattgactt gaacaaaaag atttttgaag
    45001 actttgatac agtcttgaaa agtaaattat aagaggtgga aatcatgctg aaattcaatg
    45061 aagaagaaca aatcaaagca ataaaaggcg cactagcttt acgtccgcaa gtagaagaaa
    45121 tcatcgataa actttatgcg gaaaaatttg acgctgtcta ttatctagga atcggtggaa
    45181 cgtatgcttc ctcgatgcaa gctgtcactt atatgaatgg gaaaagcaac ttgcctgtct
    45241 ttgtacagca tgctgcagaa tattacacta ctggaaacaa aagattaaca aaagattcta
    45301 tcgttatttt gtcctctgtt accggtacaa ctcaagaagt agtgaaagca gtagaacaaa
    45361 tcaagaaagt aggagcgaca ctgattggat ttatcgataa agcgaacagt aagttgtctc
    45421 agctatgcga ttttgtggtc acttatccag ctcctggaac agaacaaatc aaatttttta
    45481 tggcagcaga tcgattgatg tatttgaatg gagaattcga agcttattca gaatactatg
    45541 aacagctcga acgttattta ccaacagggt tagtggaagc agagaaaaaa gcagatgcat
    45601 ttggcttatc atttgcagaa aaacatcgac gtgatagtat gcattatttt attggagcag
    45661 ggaatcaatg gggagctgtt tattcatatg ccatgtgtta ctgggaagaa caaagctggc
    45721 ttccatcgaa atctatccat gctgccgagt ttcttcacgg gacgttagag atcgtagaag
    45781 aaacaacccc agtcacatta tttttaggcg aagatgaaca gagagtgtta tctgaacgtg
    45841 tggctaaact tttgccaaaa atttgcagca attatacatt gatagacaca aaagactatc
    45901 cagtagaagg tatcagtgaa aaatatcgcg gacgtgtttt gtctttctta ttgatgcatg
    45961 tagtgacaca acgcatcgat gctcatgtgg agcagttgaa ctgccatcca ttagagatac
    46021 gccgctacta tcgtcagttt gattattagg atagactgga taaaaagaat ataaaaaata
    46081 aagagagcag cgataactgc tccctttatt tttttaaaat attggcatca attacgttat
    46141 aaaacacatt t
//
LOCUS       DAFEIE010000015        45605 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFEIE010000015
VERSION     DAFEIE010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.015"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            5..823
                     /locus_tag="LP345_000946"
     CDS             5..823
                     /locus_tag="LP345_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBL1759747.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(926..1123)
                     /locus_tag="LP345_000947"
     CDS             complement(926..1123)
                     /locus_tag="LP345_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759748.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            1292..1870
                     /locus_tag="LP345_000948"
     CDS             1292..1870
                     /locus_tag="LP345_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL1759749.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            1965..2102
                     /locus_tag="LP345_000949"
     CDS             1965..2102
                     /locus_tag="LP345_000949"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759750.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(2915..3418)
                     /locus_tag="LP345_000950"
     CDS             complement(2915..3418)
                     /locus_tag="LP345_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL1759751.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            3777..4802
                     /locus_tag="LP345_000951"
     CDS             3777..4802
                     /locus_tag="LP345_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1759752.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            5149..6027
                     /locus_tag="LP345_000952"
     CDS             5149..6027
                     /locus_tag="LP345_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBL1759753.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            6503..6619
                     /locus_tag="LP345_000953"
     CDS             6503..6619
                     /locus_tag="LP345_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL1759754.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            7547..7885
                     /locus_tag="LP345_000954"
     CDS             7547..7885
                     /locus_tag="LP345_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759755.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            7979..8209
                     /locus_tag="LP345_000955"
     CDS             7979..8209
                     /locus_tag="LP345_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759756.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            8609..8980
                     /locus_tag="LP345_000956"
     CDS             8609..8980
                     /locus_tag="LP345_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBL1759757.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(9254..9946)
                     /locus_tag="LP345_000957"
     CDS             complement(9254..9946)
                     /locus_tag="LP345_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1759758.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(9949..10734)
                     /locus_tag="LP345_000958"
     CDS             complement(9949..10734)
                     /locus_tag="LP345_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1759759.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            10971..12371
                     /gene="lacG"
                     /locus_tag="LP345_000959"
     CDS             10971..12371
                     /gene="lacG"
                     /locus_tag="LP345_000959"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBL1759760.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            12396..12713
                     /locus_tag="LP345_000960"
     CDS             12396..12713
                     /locus_tag="LP345_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL1759761.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            12726..14399
                     /locus_tag="LP345_000961"
     CDS             12726..14399
                     /locus_tag="LP345_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBL1759762.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            14413..16044
                     /locus_tag="LP345_000962"
     CDS             14413..16044
                     /locus_tag="LP345_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBL1759763.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            16916..18106
                     /locus_tag="LP345_000963"
     CDS             16916..18106
                     /locus_tag="LP345_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HBL1759764.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            18240..20429
                     /locus_tag="LP345_000964"
     CDS             18240..20429
                     /locus_tag="LP345_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1759765.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            20426..22219
                     /locus_tag="LP345_000965"
     CDS             20426..22219
                     /locus_tag="LP345_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL1759766.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            22419..22733
                     /locus_tag="LP345_000966"
     CDS             22419..22733
                     /locus_tag="LP345_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1759767.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            22754..23131
                     /locus_tag="LP345_000967"
     CDS             22754..23131
                     /locus_tag="LP345_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1759768.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            23141..23914
                     /locus_tag="LP345_000968"
     CDS             23141..23914
                     /locus_tag="LP345_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759769.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            23936..25339
                     /locus_tag="LP345_000969"
     CDS             23936..25339
                     /locus_tag="LP345_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL1759770.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            25521..26705
                     /locus_tag="LP345_000970"
     CDS             25521..26705
                     /locus_tag="LP345_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1759771.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            26702..26992
                     /locus_tag="LP345_000971"
     CDS             26702..26992
                     /locus_tag="LP345_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759772.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            26989..27210
                     /locus_tag="LP345_000972"
     CDS             26989..27210
                     /locus_tag="LP345_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759773.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            27252..28031
                     /locus_tag="LP345_000973"
     CDS             27252..28031
                     /locus_tag="LP345_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBL1759774.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            28098..28592
                     /locus_tag="LP345_000974"
     CDS             28098..28592
                     /locus_tag="LP345_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1759775.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            28648..29286
                     /locus_tag="LP345_000975"
     CDS             28648..29286
                     /locus_tag="LP345_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759776.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            29358..29753
                     /locus_tag="LP345_000976"
     CDS             29358..29753
                     /locus_tag="LP345_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1759777.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            29737..32190
                     /locus_tag="LP345_000977"
     CDS             29737..32190
                     /locus_tag="LP345_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1759778.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            32187..34214
                     /locus_tag="LP345_000978"
     CDS             32187..34214
                     /locus_tag="LP345_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759779.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            34211..35140
                     /locus_tag="LP345_000979"
     CDS             34211..35140
                     /locus_tag="LP345_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBL1759780.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDPIGYGDLSSRYWQDHLIGARRVIHN"
     gene            35157..36086
                     /locus_tag="LP345_000980"
     CDS             35157..36086
                     /locus_tag="LP345_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1759781.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            36331..36447
                     /locus_tag="LP345_000981"
     CDS             36331..36447
                     /locus_tag="LP345_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBL1759782.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            36463..38382
                     /gene="tet(M)"
                     /locus_tag="LP345_000982"
     CDS             36463..38382
                     /gene="tet(M)"
                     /locus_tag="LP345_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBL1759783.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            38480..38668
                     /locus_tag="LP345_000983"
     CDS             38480..38668
                     /locus_tag="LP345_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL1759784.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(38726..39079)
                     /locus_tag="LP345_000984"
     CDS             complement(38726..39079)
                     /locus_tag="LP345_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759785.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            39610..40032
                     /locus_tag="LP345_000985"
     CDS             39610..40032
                     /locus_tag="LP345_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1759786.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            40029..40259
                     /locus_tag="LP345_000986"
     CDS             40029..40259
                     /locus_tag="LP345_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759787.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            40757..40957
                     /locus_tag="LP345_000987"
     CDS             40757..40957
                     /locus_tag="LP345_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBL1759788.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            40984..42177
                     /locus_tag="LP345_000988"
     CDS             40984..42177
                     /locus_tag="LP345_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1759789.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(42245..43810)
                     /gene="guaA"
                     /locus_tag="LP345_000989"
     CDS             complement(42245..43810)
                     /gene="guaA"
                     /locus_tag="LP345_000989"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBL1759790.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(43869..44792)
                     /locus_tag="LP345_000990"
     CDS             complement(43869..44792)
                     /locus_tag="LP345_000990"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBL1759791.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            44988..45593
                     /locus_tag="LP345_000991"
     CDS             44988..45593
                     /locus_tag="LP345_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1759792.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
BASE COUNT        15130 a         7548 c         8968 g        13959 t
ORIGIN      
        1 tggcatggtt gaatggctat tgagacttga accttggcag caagcacttg ctgggacagc
       61 ttttacttat tttatgacag ctcttggtgc cgggttggtt tttttcttta aagaaatcaa
      121 aaaagaagtg ctaaacttga tgttaggatt tgcttctggt gtcatgattg ctgcaagttt
      181 ttggtctttg ttagatccgg ctattacaaa agcagaagaa aatggagata ttgcttggct
      241 agttgtaagt attgggtttg gtttaggcgg tgtgttttta tatatggcag ataaaacact
      301 gccccatatg cattttggac cacaacatga agcagaagga ttgcctaccc atttaaaacg
      361 gacgatcttg cttgtttttt ctattacatt gcataacatt cctgaaggtt tagccgtggg
      421 ggtagcattc ggtgcagcag caactgcgga taatccgaca gccgctatat tagccgctgt
      481 ttcggtggcg ctaggtattg gtatccaaaa cttcccagaa ggagcagctg tatcaatccc
      541 gttgcgacaa gaaggtctga gtcgtaaaaa ggcctttgtt tacggacaag cttctggaat
      601 cgttgaacca attgctggag tgattggagc gctactagta acgaaagtgg agctgctgct
      661 tccttatgca cttgcttttg ccgcaggagc aatgatttat gtcgtggtgg aagaattgat
      721 ccctgaagca cagcagacat tgtccagcaa acgtcatttt gcagtttttg gcgtcatgag
      781 tggatttatc attatgatga ttttggatgt ggcattagga taaataaaaa aaatatatat
      841 gatatatcaa atagggccgc gaacttatat cgcgacccta tttttttagt aagttatatc
      901 ataatgaagt gaatggtatc atacattaat aatagttttt tctatgtgta tttcctttga
      961 tccagcgaac aagccagatg ataagtgcga ttgggattag aactttgacc gcaaaccata
     1021 aaagcccgct taggacactg acaaaaagac tgatgacgaa gctagctgca attagcacta
     1081 aaagaaccat gaagatattt aagaacatat ttttttgacg catacaaaac cctcctcttg
     1141 ttcattcttt actatagaaa aagtataaca gggattgttt aaaaacacct ccaactgaag
     1201 actgattttt acttcatcta cttaaatgat caaacaattg ctttttctct ggtttatcat
     1261 ctaaaataga gcggaaaagg aggagaatat catgcctaaa aatcgtcttg aagcatttac
     1321 agatgctgta atcgcgatta tcatgactat tttagtttta gaacttcatg aacctaacgg
     1381 agacacgtgg gaggcgctcg ctgcattagg ttaccgattt tttatctata ttgtcagttt
     1441 tatcatttta gcgatttatt ggaacaatca tcatcattta tttcaagttg tacataagat
     1501 aaatggacgg gtcttatggg cgaacagttt ctttgttttt gcgctttcgc tttttccgtt
     1561 tgcaacttca tggatcagtg agtacatcaa tagcctggct ccagaaatga cttatggttt
     1621 tgttaccttg accgctaata ttgcgtatta tatcttggca aaagaacttg tcaaagcaaa
     1681 taaaggccac gagaaagcat tgaaggcgat gttgaataat tacaagaaat cgtatctatc
     1741 gattggtttg aatgtgttag gaattgtctt agggtattta gtagcgccag tagccgtgct
     1801 gatcgcaaac atcgtgattc tagctgcttg gatcatccca agtcgtacca tcgaatcaca
     1861 atatcggtaa aatgatccgt gtttaaaatt taagagaaaa atatagaaaa aataaataaa
     1921 cgatcaaata tccgagtgat actagtattc aaagagggat gcagatggat caaaaaagaa
     1981 ttcatgtagg actgattact agttttgtca cgatgcttat ttatttggat caaggtcatt
     2041 tgacttggac agtagttggt gtcgtaggat ttttgacatt attcacagca ataaaaaaat
     2101 aaacatcttt atgtaatctg atgttctatc tatttaagaa aagcatgttt acagcagtat
     2161 gattctgttg taaacgtgtt tttatttgtg gaaaatttaa tttttagaaa agtgtatcga
     2221 aaaatagata gttagttttt ccacagtgga taacttcgta agagataaaa ataaaaaatt
     2281 agtcaaagaa gggcgtatag atttcttttg ataggagata tacaacagaa atgaataaat
     2341 attaacgtgt tttcaaacag tataaaacgg tgtggttttt ggaataaaaa aataacatat
     2401 ctcattttac gcttttgtta ttttatactt aaaaaataac gacacagaaa ataccgtgtc
     2461 tcagatttct ctactacttc taaaaactac tgtttttttc ctttgaaatg ccttcaaaaa
     2521 gtaggatcag gcagaatata ctggcagaat caaggagaag ggagcctaaa taaggagaaa
     2581 aaccatagaa aatataaagt aattacttat aaaacaagct ttttatagaa aaataatata
     2641 cctgagtagg gtataaatta agacggaatt cctttctaga ttgagatatt gactaggaag
     2701 aatgttaaga ttttaagcct ttaagctaaa aaaaaaccct ttttgttaaa taaggggaat
     2761 atagcctgtc agtttcaaac tgcaagtcgt cctgctgcaa taatatagta gattagagat
     2821 gaaaatagat ttttttaaac caatgactga ataaaaagac cgtcatagat acacattgga
     2881 atgtgtctat tacggtcttt ttttacgaac gattttattg aagacggaca gttcgggtca
     2941 aaaataaaaa agctacgatc agaaataaga ataaaatgta tcccaaaata atggctagac
     3001 ggtctaactt atttgtcgat agatgtttgt ttagaagttg ataggcccat aaacctatca
     3061 gtcctcctgt tgtattagtt atcaaatcag tgatgtccgc tacgccaata ccgaatagga
     3121 attgaatcaa ttctgccaag aagcttacaa ggaaaataat ccctaatttt ttagaaaaag
     3181 aaagtctctt gaaattgaca ttcaaaagca ccccaaaagg aaaaaagaca atcaagttat
     3241 aagtggtctc acgtaatacc gtcgtatttt caaaagaaaa agtagaaaaa gggacgagat
     3301 tgacattgct gtaagaataa gtgagaaatt gtggaagatt aaatgatagc ttgaataaaa
     3361 tcaaccataa tagaaagaat aaataaatcc ctaataaaaa ttttgataca taccgcatag
     3421 acatctcctc catttaaaaa gtataccatc gaaaaccgct gaaaaatcat aaaaaagtat
     3481 gaagtttaag gaccaacgta gttatcgtac gaaaattaga agcttttttt tgttgggaat
     3541 ccggtttctt taacaaagct aagatagcga gttgcttgga aaagttgcta tcttttttct
     3601 gtcaaaacga ctcggaatgt tcgttttttg ttctaatttc tccaagttgt ttactttttg
     3661 atactaagtt tatgaaaaat caagaaatag ttgttatact aggtaatgct gacaaacggg
     3721 attggcattt catcttggtt cagctttttt tccaattact aggaaggagg gatagattgt
     3781 tcaagactta ttttcgtttc aataaaatac aagataatcc ttttcgtatc atgaatctga
     3841 tgctacttat ctttattgta ttatggttag gttacataaa tcatgatttt ttgatttcaa
     3901 gtttttcatc attagggatc tttacttttt tctattatca aaacataccg atgaaatatt
     3961 tgctgaaacg tatgtttctg atcggttgcg gactgttggt tgctttcgtt ttggggatct
     4021 tatcgactta tgttttatgg cttgaaccat ttgccgtagc tttggttgct ttttccagca
     4081 gattcgtgtt gcgattattc catatttcta aaccaggtgg cttgtttttt gcgatgcttt
     4141 ctgccatggg aacgagcatg cagctgccaa tcgctcaatt accgatcgtc tcactttatt
     4201 tttttatggg tgtcgttttt gccctgattg cggcagtgat tacaaaatta ctggattcac
     4261 ggcctgagca gacaattgaa aaagcaactt taaaagaaag atttcacgaa gagcctttag
     4321 tgatcattga ttctgttttc tacagcgctg ccttatttct ttccgtttat gtcagtcacg
     4381 gcttgaatct gcataatcct tattggttga ccttgtcatg tgcatcgatt ttgctagcag
     4441 aaaacttgga tgcgatgaag catcgacaag tccaatatct gattggatcg atgggtgggt
     4501 tatgtgtgtc ggcattcttg tcatttgtgc cgtttacgca gttgcagacc atttttctga
     4561 tcacttttct atatggaatc gcacaatttc tagttgctag aaattatgca gttgctaata
     4621 tttttcttaa tccgatggcg ttgatgctat ctacacttat tcgtggagca tacttgattt
     4681 ctttgatcga atatcgtttt ttagggatcg tcataggaag tttcatcggt ttaggtgttg
     4741 cgtgggtaat gacggttggt ttgcaacatt atttaacggt tgttcgtcaa aaattagaat
     4801 agaaggacaa atatatgtgc caaaagaggt tatgacaaga tttttgtcac aacctctaat
     4861 tcaaggtgtt caaaagccag attctcagca ttaagtcaaa ttcacacaaa aatgtggaaa
     4921 ggaactttca aaaaaatttt atatttattc tatcaaaaaa ttttatattt attctatcaa
     4981 aaaattttgt ttatgatggt aactgaataa actttcctga gatggtcaat gctttccttg
     5041 aaagtcttac agatattctt tcttcataga aagtttaagt tttatagtta gtgtacaata
     5101 aaagtatgtt tataccatat ggtgtccgga taatcagtca tttaaacaat gaggttcaaa
     5161 gatatgaaaa ggggaaattt gatgaagaaa ataagcaatg aaatccaaat tctggcagaa
     5221 actttaactc ttcccaaagt cgttatagag caaatgattg tacaagcaaa aaacatcctt
     5281 gatgaggtgt ttgagcaata tagtcatgaa ctaatggatc ctaataaagc aaaggcgact
     5341 gcaaagaaaa tagacaaagt ctatgaagag gaaccttttg cagcattagc tatttatcta
     5401 tatgcagctt ctcaaagttg gaaaaaaatt tatcaaccat tgaagattcc aagaactatc
     5461 tatttggcaa caatgaatgc ttttactaga tttattcatg aacatttcca agtaacagga
     5521 agctatcgct ttgaccgtgg tttttggatt tggcattaca ctagtggctt gatctttcgg
     5581 attggtgaat tggagtacga aatgacatat tttccgaaag ggtacacgga tctaagatta
     5641 gaaggaaagc agtgcctttc tcttcatatt ccttccgatg cagatttatc tcagaataag
     5701 ataagagata gttacgaaag tgccattcgt ttttttgaac tttattttcc tgattaccat
     5761 taccaagtga tgtacacaga tacttggtta ctatcaccca atcttactaa atggttgaaa
     5821 aaagagtcaa aaatctgtct ttttgcagcc gattatcgat tattatcagt tgatgaacag
     5881 gacgatagtg gagtcccttg gatctttgga cgagtagatg cccaaataca tgattatcca
     5941 gaaagtacga gtttacagcg acaagcaaaa gagcaattgc ttgcaggcga gcacattggc
     6001 tctggcttag gtattcttac ttcataagtt tagtacttcg aaatagttta aaagagcgtg
     6061 agacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg gcggaagcag
     6121 aagcaactcc ttcggaaata agctgaaatt cacaaaaatt tgaaaagcaa ttttcgtgaa
     6181 tttcttctta tttcttggag ttaaacgctt ctgtcccagc ctctttttta gtgttctatc
     6241 gaacacacag tacgttcaat aggtaaacta gctataacaa tagatattaa agttaacgga
     6301 caagagggcc ttttttaggt agctaaaacg taataatgaa aatttatttc cagagatagg
     6361 agtcaatcag ctagtctgat cgactgtttt aacaagttga ctttcatttt aacttttgat
     6421 accatttaaa acacaaatcg taattgtttc gatttgtgtt ttttagcatg actacaatca
     6481 aagaagaaag tgggtcgtcc atatggaaaa aacagatatc tcaagtgcat accgccgctt
     6541 gaaaagccca aatatcaaaa cacgaaaacg tgcgctgaag atcatcaaag atgtgaaacg
     6601 gaatagtggg aaaaggtaag aagaaggaaa cttaattaaa aaaatagccg aaaaacgttt
     6661 ttcggctatt ttcaataatc ggtttttgtg taaggtttcc gaaagaactg ctgttgattt
     6721 tccattttta acatatgata aattggtaga atctttcttt tcaaattgat accattccct
     6781 aattccagtt atatagttaa ctacagaacc acaaagcacg tacgtttata aaagtattat
     6841 ctgtagttat ttttcaattc cctttcaacc tcttattttg accagtagta ttgatcactt
     6901 taccttttaa cacctttgtt cgtttttgaa acatttttag tcaagaatgg aaacgtaact
     6961 acataatcaa aggttttgcg aaatatttca tgaaatattt catgtagaag cgagcaatac
     7021 ggttgcaaat aaccattatc gtttaataag cagttacgaa agctcccaat atctctaacg
     7081 ttcagctcac tccatttctt ttcttcaaaa aaatcagtga ttcgtatctc tttctatttg
     7141 tcgaaaaagt taactttaaa aagtaacgcc gaaaaaatat gcaaaaaaat aaaaaagcag
     7201 ttactattgc tagaataaca tcaaggaata ataagttttg gttttcagat aatagtcgat
     7261 aagttgtgta ttggaatttt agatacagta ataaagtatt tttcatgaaa ttttgtgaga
     7321 atcactatta caagtatctt taataaaatt aatggttaag gaggaactta aagtagaatg
     7381 taaatgaata gttgtagtca gtcgattgtg atactagact caaagttgca ggaataagtt
     7441 tttcaatttg tgattggaag ataaaaaatg aaaaagaagg gctttttttt atactttgtt
     7501 gattgtagtg tttattttcc ctctgtttag ccaagtaaca ttttctatga ctcaaccagt
     7561 ttcaagtgag gaacatgata acctttttcg tgctacagaa gagtttaaga aatatcagga
     7621 aaatattgtt ccggagactc cattagctag tgagccaatt actgatattg atggaaacca
     7681 aataggatgg tatatacagt acgaagttat ggtggtaaat aatgactcaa tagtaaaaaa
     7741 tacagtaggc ttagagctaa caccgattga aaaggtgagt tcattgttaa cgtatattta
     7801 tactgatgaa agtgacgaga ctgagatcat tttaacggat tactcaaaaa ttgctactga
     7861 taaaaagtat atattgtgga tgtagacact agtgaaatac tttatgatat agaaattgat
     7921 gaaaatttac tagatgtagc acaagaaatc gatcatcaaa agcaggaagc tattcgatat
     7981 gctggtagaa aagggaaaag aaaatattta ttacgtgaat gtagcaaaag ttagagaaga
     8041 tgaaaatgag tggaaagaat tcaagagtcg ctactcaatt aactcgactc cgacatttac
     8101 agtttacaga gaaggatcga tagaaaaaac tgttttttgg actaaagaaa gtggaatgtc
     8161 tttagctgaa gtagaagagt ttttggatta tgttagtatg caacagtaag ggagttctta
     8221 ttatgaaaaa ttttgacaca tattatgtta ttgttttttc gatatctttg ctgttaatat
     8281 tactaacttt aatgcagtat aaagagtatc cagagtattt tattttaact tttgtatatt
     8341 tagtaagtag ctacacactt ctatataaat tcagaagttc ttctagagtt tctaaagttt
     8401 gtttcttaat tagcttattg attctataat atttttgatt tatataggaa attaaaaata
     8461 ttatagaatc aacactcaga gaacgggttg gtttttaata gatttaataa gtactgataa
     8521 tgaaatttct cctggttggg aaaacgaagt tggttaccct gtagaagaat tttttcaaga
     8581 ttactttgcg gagtatgccg ataggataat gagagattac gtaacagata aaactcaaga
     8641 agtcatcaat caatcccagt cattaaatga attatctgat aaggcgaaag aagaagcagt
     8701 tgccattatt tcttcaggga ttagtgacta tattgatatg agtggtgaaa tcaattatgg
     8761 cgataaagac aaaattgtac gcatgataaa agcttttatc aaaacttttg atgtgaaggc
     8821 agatcttaag tttaatgata cttacctagt aggaaaatta attaatatcc ttgggacaga
     8881 gaaagatacg gaaacgttta tttcctcttt gtctatgttg tttacagata agcatttttc
     8941 aactcagctt ggtggagagg aactagtgga aatcttttaa ccattacgcc cagcattaat
     9001 aaaagtatat caaaaaagta ctcctgatga tttttaagat tggtttgaga aataatgtga
     9061 aaacactatt tttaatgtta attatagata gagatgaacg cgtcatatgg ttaaaagaat
     9121 gaaaaagtca aagatacact gctatatttc actaaggata tagcagtgta tctttcatgt
     9181 cgtttcactg gcagtttttt ataaaaggag gtgtgcattt cagttgcttt tctttggtag
     9241 ttagttgaat cgtttaagaa ttaacggatg tggcagacag gtgctctgtc caaaaaccag
     9301 taaaatcttt gatggttcca tctttattta gctgtgcctg ttcaaatact gttttgtttt
     9361 taccgaatgg atcaattgca ataattgttc cgatccccgc acgtttggca gcaagtaatc
     9421 ctgagtaagc atcttcgata acaagacaat cagccggagc taagctcagt ttgtctgccg
     9481 ctttaagaaa aatatccggt tgcggtttcc cagggaaaga gccgtcgtca tagacaatct
     9541 tgtcccagtc aaaccagcgg gctaaatcga aaatatcaaa ataaaaagca acattctctt
     9601 tgacagtagc cgtggcaatc gttaatggaa tctgttggtc agtcagctgg tcaagagtcg
     9661 cttcaagccc ttttgtcaac tgaagctcgt tttcattttg caagcaaagc atacgataat
     9721 agctttcttt ttcttctgac aatacggcga tctcagaggc ggtcaaatgc tctgaaatga
     9781 aatgtttcaa aatctccgta ttcgtccgac catgaatatt ttttaaaata tcctcgtctg
     9841 ataaaccatc ttttgtatga tcatgtatca tatgcagcca agcagcttca tgcagatgag
     9901 agtccaaaaa cattgttccg ttgaaatcaa atataatccc tttcatagtt acgctcctat
     9961 agtggtattt tcggttgaat cagcaatttg cagatcgaca tattgtgcat agtgctcttg
    10021 aacctcccgc gagatctggc gatccgtaat gagcagatcg aaatcatgca aattataaaa
    10081 cacataaaaa tcatctcgat tgaatttttt attatcaacg agtagatatt tcttacggga
    10141 attatttaga gcgatctgct gtgcttctcc ttcttcggta ctgtaagtag agatcgcttc
    10201 gttgtgaacg ccatttgaac tgataaatgc ttttgtaaac tttagtcttc ttaaattgtc
    10261 gttggtgatc ggtccgacaa atgcgccggt atttttccgg aaatcaccgc caatcagtag
    10321 aatttctggt ccatctgctt gagcaagaat atcaaaaact ggataattat ttgtaatgat
    10381 ccgaattttc ttgttcagta aatgcgtcgc caatagttcg attgttgtac ctggtcctaa
    10441 gaaaatcgtt tctccctcgt gaatcaagga ggctgctgtg gcagcaattt cttttttttc
    10501 ttgaatctgc agagtggctt tttcagtgtg agaaagttct tgatctaaag tgtaggaaag
    10561 actttgagcc cctccatgga cacgcagcag cttgcccgat ttttctaatt catctaaatc
    10621 tctgcgaacg gtcatatcag aaacatctaa ttgattgatg atttcattaa cggtaaggat
    10681 tcctttttta ttgaccattt ctacgatagt aagcaatctt tcttttttca acattgtctt
    10741 cacctctaat ttaaggataa tctatcatat aaacggacaa cagtcaatct aattcgaaca
    10801 aaagtaaaca tttagggtgg tttttatgtt tgttacaata gattttattg ctgttttctg
    10861 gtttttatga ttatttgtgt ttgtttttgt tgacaaatgt tttggatgcg tttacaatgc
    10921 aatcagttag aaagagcgaa aactgattat agatttgagg agagatgtac atgcttaaat
    10981 taccagaaga ttttattttt ggcggagcca cagcagccta tcaggttgaa ggagccacta
    11041 aggaaggtgg caaaggcgct gttgcttggg atgacttttt agaggaacaa gggcgattca
    11101 gtcccgatcc ggcaagtgat ttttatcatc aatatgcaaa ggacattgaa ttgtgtgaac
    11161 gttttggtgt aaatggtcta agattatcca ttgcttggag ccgcattttt cctgatggag
    11221 ctgggaaacc aaatccagaa ggaatcgctt tttatcatcg tgtgttcgaa gaatgtaaga
    11281 aaagaaacgt aacgccgttt gtgacgttgc atcattttga tacccctaaa cgtttgtttg
    11341 accatggaga ttttttgaat cgagaaacaa tagaagcatt tgtttcctat gccatttttt
    11401 gttttcatga attcaaagaa gtcaaggtgt ggagtacctt taatgaaatc tatccagttg
    11461 caaccaatca atatttgtta ggtgttttcc caccaggaat caaatatgat tttacaaaga
    11521 tcgtcgcctg tcttcataat atgatggttg ctcatgcccg tgtagtgaac tatttcaaag
    11581 aaaacgaact tccgggtgaa attggtgtag ttcactcatt agagacgaaa tatgcggcaa
    11641 cagacgcgcc ggaagataag catgctgcct ttttagacga tgcattgtcg atccgtttct
    11701 tattagatgc tacctattta ggctattatt caactgaaac cttgactgct cttgatgaga
    11761 tatgtgaagc aaatcaggcc agctatcatt ttcctgaaga agatttcgtt gaattgaaaa
    11821 aagcatccac gcgtaatgac tacttaggga tcaatcacta ccaatgccat tttgtcaaag
    11881 cttacgatgg agaaaatgca atccatcata acggtacggg tgaaaaaggg acctctgttt
    11941 ataaagtgaa gggaatcgga gaacgtattt ataaagaagg aattcctcga actgattggg
    12001 actggctgat ttatccagaa ggtctatatg acttgttgct gcgaattaaa agcgattacc
    12061 cacattacaa caaaatctat atcactgaga acgggatggg gtataaagat cagtttgaag
    12121 atggcattat tatggatcag ccgagaatcg actatttgag agtctatttg gaatccttaa
    12181 gcaaggcgat aacagccggg gtaaatgtga aggggtattt tttgtggtcg cttatggatc
    12241 ttttctcatg gacaaatggg tataacaaaa ggtatggctt gttttatgtt gattttgaaa
    12301 cccagaagcg ttacccaaaa gaatcagctt actggtacaa gttggtcagt gaaaccaaaa
    12361 cgattattta ataagtgata atggaggaag aaaagatgaa taaagaggaa ttacaaatgc
    12421 ttggttttga gatcgttgca tattcaggcg acgctcgcag tacattattg aaattattga
    12481 aagaagtaag acaaggaaac tttgaacatg ttgattcggc gttgaaagaa gccgacgaaa
    12541 atttaaccct tgcacataat tcgcaaacaa aaattttagc ggaagaagca tctgggaaag
    12601 agatggagat gggattcatt tttatccatg ggcaggatca tttaatgacc actttattgc
    12661 tgagagatct gattcaagac tttattgtac tgtacagaca gaatcaagga taggagaaga
    12721 acgctatgga tggaatcatt aaacaaatcg aaaaagggaa accatttttt gaaaaaatct
    12781 cacgtaatag ttatttagga gccgttcgtg acggattttt aacagcgatg ccagctattt
    12841 tattttcaag cattttcatt ttgattgctg cggttcctga gatttttggt taccaatggc
    12901 ctgaatctgt ctccacatgg ctatggaaag tctataatta ttcgatgggt gttgtagggt
    12961 tactcgtttc agcaaccact gctcgctgct tggctgattc gatgaatcgt cgcttaccga
    13021 aaaacaaagt aatcaacacc acctctgtga tgctggcctc tgtggtaagt ttcctgttgt
    13081 taagcgtctc tccgattgaa ggtggatttt caacggaata tatggggaca aagggactac
    13141 tggcttcctt tgtcgctgca tttttaacag ttaatttata taagttttgt gtgctgaaag
    13201 atattaccat taaaatgcct aaagaagttc ctggaacgat ttcgcaaacc ttccgagata
    13261 tttttccttt ctctttttca gtatttgcgg ccgttttaat tgatttaggc attcgacaaa
    13321 tcttccaaat ctcatttgca gaagcaatca ttacggtgct gcagccgcta tttacagcag
    13381 ctgacgggta cttaggaatc gctattatct ggggagcgat ggcgctgttt tggtttgtcg
    13441 gtgttcatgg accgtcgatc gtggagccgg caattgcggc aattatctat gccaatgtgg
    13501 aaaccaatct gcaattgttc aattccggtg aacaagcttc taaagtactg acggtgggtt
    13561 tagggaattt tgtaggaact atgggaggaa ctggggcaac attggttgtt ccttttatct
    13621 tcctactctt tgctaagtct aagcagttga aggcagttgg gaaagcttcc tttattccag
    13681 taagtttcgc tgtcaacgaa ccattgctat ttgcggcacc catgattttg aacccttatt
    13741 tttttattcc atttttgtta acacctgttg taaacgtttg cctgttcaag ttttttgtcg
    13801 atgtattggg catgaacagc tttatgtacg ttttgccttg ggcaactcca gcaccgatcg
    13861 gtttggttct aggaacgggc atgggtatct tagcttttgt tctagcagcg gttctaatcg
    13921 tcgttgactt cctgatctat ctaccatttt gcaaagcata cgatgctgtc ttagtagaga
    13981 aagaagcaca aaaagcagag gtgatcgcaa ccgaggaagg tgcttctgcc gatgtacgtg
    14041 aggaagtacc tgtggcagcg agtcaagtta tcagcgatgc aaataaagaa atcaatgtgt
    14101 tggtactttg tgctggcgca gggacaagtg cgatgttagc taatgcttta aaaaaaggtg
    14161 catctgaatc gaaagcaccg atcagtgcaa tggcgggtgc ttatggttct cattacgaaa
    14221 tgctgcagga ttttgatatg gtggtcttag caccgcaagt caattcttac tatgatgata
    14281 tcaaagaaga caccgatcgc ttaggaatca agctggttgc gacaaaagga gcagaatata
    14341 tcggattaac gagagatcct gaaaaagctg ttcagtttat tctgaaccaa tttcaataaa
    14401 ggaggagcca taatgaaaat gggaatttgg ttgcgtaaag ctgttttatt tgcagctgtg
    14461 ttaggggctt tgggggctgt ttcaaaaact gttgaagcat ctgccagcga atttattcgc
    14521 ggagcagata tttcgatcct gtcagatatg gaaaaatctg gtgcaaaata ttatgaagac
    14581 gatatttcaa aagatgcctt agagatttta aaaaataatg gtgtcaacta tgttcgactg
    14641 cgtttgtggc aggatcctta taatagtaat ggagaaagtt atggagcagg gacaaatgat
    14701 ctggaaacga cgattgacct tgcaaaacga gcaaaaaatc tgggacttaa ggtgctgctg
    14761 gattttcact acagtgattt ttgggttgat cctgggaaac agaatcttcc taaagcatgg
    14821 caaggtctga cctttgaaga aatgaatacg gcattgtacg actatacaaa gaacgttctg
    14881 tcggaaatga agcagctgga cgtttatcct gatatggttc agatcggcaa tgaactgaat
    14941 agcggaatgc tctggcctta tggcaagtct tggggagaag gcgggggaga atttgatcga
    15001 ttggctgctt ttttgaagtc tggtatccaa gctgttcgag acactcaacc taaaacaact
    15061 ccagtaatgc tccacttagc tgatggtggc gatacaggag catttacttg gtggtttgat
    15121 gaaatcacga gtcgaggtgt gtcatttgat ttaattggag tgtcgtatta tccgtattgg
    15181 cacggttcaa tgaatgaact tcaaaccaat atgaatgcga tcagccaacg gtatggtaaa
    15241 gaagtgatcg tagttgaaac agcttatggg catacaacag cgaatgccga tactatgcca
    15301 aatgcttttg gtgaagccga agcagctgcg gggggatatg aaccaacacc gacaggacaa
    15361 gcagagtatt tgctggatct tgccgatcgg attcaggcag taccgaataa tcgcggggcg
    15421 ggcttcttct attgggaacc tctttggtac aacggaaatg tgagttgggc aacacaagca
    15481 ggtatgaatt atctcagtgt tcaatccact atgggaaacg aatgggacaa ccaagcgatg
    15541 tttgattttg ctggaaacgc cttgccaagc ttgcgtgcgt ttaaacaagc aggggcgcaa
    15601 ataaatctag ttaaaaatgc aagtttcgaa agcgatggac caacgaccag tccttccaat
    15661 tggcaaacct ggtttcaaca aggaaccgct aagggtacga tcaaaacgga agcgggcact
    15721 ttttttgggg actacaaact aactttttgg caggatcaag catacgaggc atcagcttat
    15781 caaaatgtta gtggcataag caaaggaact tacacattga gtgcctatgt aatgtctggg
    15841 ggagagtttg atactaatca gttatatatc aaaaattatg gtggagcgga actaaatact
    15901 gcggttgtta aaacaagtga atggacaaaa attacaatca aagacattcc aattacaaca
    15961 ggtgtttgtg aaattggggt ttatagcaag gcttcaggaa atgcttggac gaacgttgat
    16021 tttgtttcat tggtgaaaca atagactgcg gatcgtttcg attcaagatc ggaggttccc
    16081 ttcagccaca tcgttagcgt agaaggcagg aatcgaacct gcacctcgcc tttgccaaaa
    16141 ataaccagaa acgatttcca gtcattttta ccaaaacgag taaagcacca gacttcatct
    16201 acactttgta ttatgctaaa gagagttcaa cgatttcgta agaagcaatg aaaaaattgc
    16261 aaaaagttgt gcagataaca taaagtttgt ttaagaaagg gtaaccttag aattccgtcg
    16321 tgaatatgat ttgagcactt agatggatag aaaaaagttc tcggaaaaca gttcgttttt
    16381 cgagaacttc tttttatgat aagaatgaaa caaattaact tatattatag tctcttttgg
    16441 tagggaacca tcttattttt aatgaaaatc aagcatttta gctattgaag aatgttgatt
    16501 tatagggatt ccccctccat attatgttgg ctctttattc ccactctgtt ttcaacgtaa
    16561 agtgtataaa acagaatgcg atactatcaa gggagttaaa acaatataca gaacagtaaa
    16621 acactataaa taaaaataaa agtgcaataa aagtgcaatt tttgcaccta atcatactct
    16681 gtttatatat gaaaactaga ttctgaatcc aatatttggt taacgagagg cgttcgaatt
    16741 tgaacgtctt ttatatatta ctttcaaata aatatgaggt agaatactat ctattttctt
    16801 tttaacccaa ttgttataat ggagagtgta aaatattttg tgtaaataga aaaaaggaag
    16861 tcccttctgt agaatagagt taccacaaca cattcacaga agagaggact tccctatgaa
    16921 cgattttact acagaaattc taaagactct agcgaacaaa ggcgatttga atgaattatt
    16981 ccgtgtccat ttggagaaag cagtcaatac gcttctcaaa acggagttaa cggctttcct
    17041 agattacgaa aagtatgatc gcattggttt taacacgggt aattctcgta acggctccta
    17101 tgaccgtacg gtcaagaccg agtatgggga acttcatctc cagattccgc gcgaccgcaa
    17161 tggtgagttc aagcaacaga ctgttcctgc ttatagacgg acgaatgaca cgttagagga
    17221 gaccgtcatt cacctcttcc gaaaaggtat taccatgtcg gaaatcgcag acttgattga
    17281 gaaaatgtat gggcattact acacgcccca aaccatgtcc aatataacaa aatcatttac
    17341 agaagaggta acggcgttta atgggcggga gcttcatgac cgttatgctg ctatttatat
    17401 ggacgcaacg tatattccgt taaagcggaa aaccgtcgcc aaggaagcta ttcatatcgc
    17461 agttggcatt cgcccggacg gatcaaagga agtattgagc tatgcgattg caccgactga
    17521 atccatcacg atttgggagg aaattttatt ggaccttcaa gagcgcggtt tgaaaaatgt
    17581 cctcctgttc atcacggatg gcttaaaggg gatggtagga gcgattagtc ggttctatcc
    17641 caaagctcgt tttcaacatt gttgtgtaca cgtttcccgt aatatcagtc ataaagtgcg
    17701 tgtcgatgat cgtaaggaag tctgtgatga ttttaaaatg gtgtatcaag cctcatctaa
    17761 agaggtggcg ttggaagcac gtggtacttt tgcggaaaaa tggaaaacca gctatccaaa
    17821 agtggttgaa tcgattcttt cgaacgatca cttgctcact ttctatgatt tccccttggc
    17881 catacgcaag agtatttatt ctacgaactt gattgaatcc tttaataaac aaatcaagaa
    17941 atacagccac cgcaaggaac agttccaaaa tgaagagtcg atggaacgtt tcttagtctc
    18001 gtcttttgat acttacaacc aaaaattcct aggtcgcagt cataaaggtt tccaacaggc
    18061 cgaaggcgag ctcgaacaaa tgctaagcca actgattgag aattagaaac aatctgcagt
    18121 agggaagaat catttacaca aaattattga cgctccctta taatgagaac ttttactaac
    18181 ataatttatg ataaacttac tatataatca tattaattaa atagttagga gatctgctta
    18241 tgtttatatc tactcttcaa attcgaaatt ttagaaatta tgaatccgaa atctttcgat
    18301 tcgataatga gacaaatact attataggtg agaatgattc agggaaaacc aatgctctta
    18361 ctgcattgag aatcttatta gatgatagtt attactatag tagtaaaaca ctaaaagaat
    18421 cagatttttt tcatggaatt caaaatgggt ggcaagggca ttggattatt atctctgcga
    18481 catttgaagg aatcagcgaa gaagaatttg acaatgagat ttgtgcttcc atttctttaa
    18541 attctgaaag tcaaacaatc ttagaagaat tgatttcaaa tgcagataaa ggtgtaggta
    18601 gtatttctct atttattaga cctaacaaag ctattagaaa gcaattattt gatatttcca
    18661 ctgaattaga ctctcatcaa tttaacgaat ttagaaattc tattcgtcta tccgactatg
    18721 aattttacta cacatctaaa tcaaatctaa atttctgtat caatgaaaat tatgataaat
    18781 tggtaggaag actcaatgac aatatagcta gtaatcctga agaagacgat gaagctctgt
    18841 tgggctcaag aattgacatg tcagatattt tcaagcatat ttcggttgtt tatgttgacg
    18901 ctcttcgaga tgttcttaga gaaatgaaaa acaatcgaaa cccagtcaaa agaatcatgg
    18961 aaacaattga atcaaaaata tcatcagata atgttgagtc attaaaaaca attatacagc
    19021 aattaaatga gactattacc agtgttcctg aaattaggaa aattggcgaa aatattaatc
    19081 ggcaactaaa tagcataatt ggttcagtgt attctcctaa tcttcttctt tcctcaacta
    19141 tgtcagatga tatgggttct ttagcaaaat ttctttcaat gaagccagaa caaaatatcg
    19201 acttagactt actagggtta ggacatctaa atatgattta tttagctttg aaaatagtcg
    19261 aatttgaagc gtgtcgttca agagaactac ttaatattat gttgattgaa gaaccagaag
    19321 ctcatattca tcatcatatt caaaaaactc tgttcgaagg attaaatctt caaaaaaact
    19381 atactcagat tctcatgacc acacattctg tacatttagc tgaagtgtct gaaatatctc
    19441 ggatgaatgt attaaaatcg tttaatggca aatctatcgt tatgaatcca gcaaataatc
    19501 tgaactcatt tgctaaagaa aagttaaaaa agaacaatct aaatctaata aacgcagtag
    19561 agagatattt agatgttaaa agaaatggat tgcttttttc taaaggtgtt atcttagttg
    19621 aaggagatgc tgaagaaata cttattcctc aaatagtaaa aaaattattt ggtataaact
    19681 tagacgaact tggaataggt ttgattaatg ttggtagtac ttcgtttgaa tatatcgcta
    19741 gcttgtttga cgatgataga atacagagaa agtgtgctat tgtaactgat ttagatgaac
    19801 aggcaatccc atcagaacat cgattgtata aaagcactgc acaagagaaa ggtcaagcaa
    19861 gaaaagaaaa attatcctcc ctttttaatg aaaacaattg ggttaattgt ttttatgcta
    19921 atacaacatt tgaaattgag tttttagatg tgaataaaga aaatattcta acttatgtca
    19981 gtccaattat agatgacgca ttcaaagata aaaaaacaat aactgcttat aaagaagaaa
    20041 tacaaagtga acaatattta gaaagaaatt tagcgatgtt aaaactagcc aatcatgttg
    20101 gtaaggggtg gtttgcaatt gagttaggtg aaaaaattga ctttttaatc aaaattccta
    20161 agtatattct taatgctatt gcttttgcat gtcaggaaat agtagatctc tcaatttata
    20221 aaaaaattct actccataca atcgacttgt acgaggaaac tacagaattg tcagctttat
    20281 cagctagttt aaaaacaagt gatacagctg atttgaatat agcaataatt tctttattag
    20341 agtactttgg taaagatgag gatgttgtgt atctaatcaa tcagatagaa aattacacaa
    20401 aaatacttta tgctgaggtt tcaaaatgac aaatatcttc gaaaaaatcg taaatgattt
    20461 aaatttagaa caaaaagatg ttgtggaaag tgaagataac ctttatgtaa atgcatgtcc
    20521 tgggagtggg aaaacaaggg tacttacaag gaaaattgct taccaagcaa ttaaacacga
    20581 tggatcacta aaaagaataa ttgctatcac atacactaat agagctgctg aagaaattaa
    20641 ggaacgccta agtttactta gtatagatga tgatattaat atttgggtgg ggacaataca
    20701 tcagttttgt cttgaattta ttatttatcc ttttaaaatg aatctctcaa gagtatcaaa
    20761 aggatttaca attattgatg attatactca aagagcttac gtcagccaaa ttaataatat
    20821 gctgaattta aatctcaaaa cgtatgaact gaacaaaatt gatttgtcac tttctcatga
    20881 ttttaaaatt aatgaagttc agtatactca agtttctgaa atgtatcaca ctatgttgga
    20941 aaaaaataaa gaaattgatt ttgatatgat tttactagta gcgtataaaa ttttaactgt
    21001 aaacagtaac gttgcacgta atattgctag taatataagg gcgatttatg tggatgaatt
    21061 tcaagatact agagaattac aatacaatgt aatagctaaa ttacttcaaa acaaccctca
    21121 aattcagtca atgtttgttg gagatattga ccaagcaatt tatggatcat tagatggtat
    21181 agctaaatca gttgaagaac tagaaatgct aactagtcac acttttcaat caaagacgct
    21241 acatggctgt tacaggtcta atcagagatt agtagacttc tactctaatt ttcagagttg
    21301 tccttacgag attgaaagca gagggaataa taaaaacgac cgtggtttta taagttatga
    21361 ttgcaaagtt actaaggagg atttacccaa cataataaaa aatataataa aggaaaagat
    21421 tgaaagcggc attcatgaaa aagatatttg tgtacttgct cctcaacact atcctctgtt
    21481 ttcactgggt gagtatttaa agaaagaatt accgtattgc aattttgatg ctataaatat
    21541 atcaccaatt aaggtaaata atcatagttt atttttcaag ttagcaattt tgtactttac
    21601 tgaatcaggt gaaaaggttc gaagaagaaa gctaattgca aacgatattt taattatatt
    21661 aaaaaatgaa tttggaatag aagttaaaga ttattttatt gacttagatt tattacagct
    21721 aataaacagt gtgaaaagaa tgtatagtgg agacgacaac ggtgttgatt tatacaaatt
    21781 tgttaccaaa catatatttg ttaatcttaa tattgacgag aaaaattacc cgtctatttt
    21841 taagcactat ctatttttta ttaacgaagt agaagatcgg ataaaaaata attcattatc
    21901 tagtagtgta tctagtttta agaagatgtt taaatctcga gatggtatca cacttactac
    21961 agcacataaa gttaaaggaa atgagtatga tactgttatc gctattaatc ttctaaacgg
    22021 gaaaattcct cattggaatg aaatttttaa tgtttctgat aaaggaatta gttcagcgag
    22081 aaaactacta tacgtaattt gttcaagagc aaaaaataat ttatttcttt tctcagaggt
    22141 gggttatttt acgagtaaag gagacttgct ttatcccact caattattag ataaaataga
    22201 atttgattat aatatttaaa atacctaggt agtcgttgtt ttaaatatag taggaatcgg
    22261 acgctcagta cggagcgtct atttttttac ccaattttga aaggaagtga acttatgaaa
    22321 ataaaaaatc aagaatcaaa aggtcgctct ccccccttta aaaccatcac acaaataaga
    22381 ttcattcaaa cataaaaaca gaaaggatag gtaaaaatat ggaacttaaa tatgtcattc
    22441 ccaatatgga aaaaacattt ggacaattag aatatgctgg tgaagggaac attgaacaac
    22501 gtcgaataaa tggcagacca accattctct ctcgtagtta caatttatac tcaacgattc
    22561 aacgagcaga tgatattgtt gtcattcttc cctccgaagc tggcgagaaa cattttgaat
    22621 ccgacgaaaa agtcaaactc atcaacccac atattaccgc agaaggttat aaaattggca
    22681 atcgaggatt taccaattac attatgcacg cagacgatat ggtgaaagca taagaaagga
    22741 aaggtgaaaa aatatgagat tagcagaagg tattgtgatt gaaaaagacc agacatttgg
    22801 cacattgaaa ttttccgcct tgcgtcgtga ggttcgtatc cagaatgaag atggtacggt
    22861 ttccgaagaa attaaagaac gtacctatga cttaaaatca aaaggacaag gacgcatgat
    22921 acaagtcagt atccccgctt ctgttccttt gaaagaattt gactacaacg cagaagtgga
    22981 attaatcaat cctgtggcag ataccgtagc gacggctact tttcgagggg cagacgttga
    23041 ttggtacgtg aaagcagacg atcttgtatt aaaaggacag acaaaacctc atcagaaata
    23101 taaaaaagaa gcgtccgaaa gtgaaaaata ggtgttgctt atgacaaaca caccattgat
    23161 tttgaaagaa attccgaagg atgaagccat ttcttttatt cggcaatacc attattcaaa
    23221 gatactccct agattgtgta aatactttct agggattttt tcagaagaaa aattattagg
    23281 cgttgtggaa ttaggctggg gtacgcaacc cctacaaacc atacgcaaac tctttcccga
    23341 cagttccctt caaaccacag attatttaga aattggaaag atgtgttttc ttccagaaat
    23401 gaatcaaacc aattattttg gcagtcaagc tctttcagct ctaattaagt ggttgaaaga
    23461 acatacggac tgtcattttt tatatacact ggcagatgga attgagggaa aatgtggcta
    23521 tgtctatcaa gcgtccaact tcttttactg cgggtatttc aagacaagtg tctatcgtga
    23581 taagcagtca tgggaaaaga tacaccctcg aagtgctcgc cttttattag aggaaaatgc
    23641 tcgctttgaa caggtagaga aaaagcattg gctttcccag gcattttgcg aatacaaagg
    23701 gattgagaaa atcaatggac gcatgtttcg ctatctctat ccgttgacaa aagaagcgaa
    23761 aaaactgtta ggacacactc tctatcgacg tcattattat ccgaaagaaa aaaatttacg
    23821 ctttgaaaag cgaatcgctt atcagaaata tgaagccatt tctcaaccaa cttttgataa
    23881 acaggctcgt atctacaata cacaattatt ttgataggtg gaaaggagga tttttatgcc
    23941 attgcttcat gacagaggag agcgaatcaa agccaacgat aagcacttgg tctatcattt
    24001 tgtactaatt tcattgctgg tagtttttct agtcgtccta ctcccttttc attggagagc
    24061 gttacaatcg gtgaactggc aagcagttca gttagataca tttttctatc aacttcatac
    24121 gccatacttt tggagcagta ttctcactgc tctttttgta tgcggactta tcagctggct
    24181 ttattatcac tatcgtatag attctataaa acagttagag caccgtcaaa agttagctcg
    24241 tatgatttta gaaaatcatt ggtatgaagc cgaagaaact caatcagagg gattctttaa
    24301 agatttaccc agcaagaaaa ccaaacaacg aatccgccat tttcctaaaa tatattatcg
    24361 aatgaaagat ggactaatcc atattcatgt agaaatcacc ttagggaaat atcaagatca
    24421 gcttttgcac ctagaaaaca aactagaaac aggattgtat tgtgaattag tggaaaaaac
    24481 gttgaaagat tcttatgtag agtatgtcct actttatgat actattggca atcgaattgg
    24541 cattgaagac gtggtagctc aagatggacg tgtcaaattg atggaatcgg tctattggga
    24601 gttcgattct ctccctcaca tgttaattgc tgggggcact ggtagtggaa aatcctattt
    24661 tattctcaca ttgattgaat ctctcctgca tacaaatgca aagctttata ttcttgaccc
    24721 taaaaatgct gatttggcag acttaggggc ggtcatgaat aatgtctatt accgtaaaga
    24781 agatatgttg gcatgtatca atcaatttta cgaagatatg attgatcgca gtgaaaccat
    24841 gaaacaacac cctaactata aaacaggaga aaattatgct tatcttggtt tgtctgccaa
    24901 ttttcttatt tttgatgaat atgtggcaat gatggatatg ctaggtcgtg aaagtaccac
    24961 cgttattcat aaactcaaac aaattgtaat gttaggacga caagcaggct tctttttaat
    25021 tcttgcctgt caacgtccag acgcaaaata ttttagtgat gggattcggg acaactttaa
    25081 cttccgtgtg gctttgggtc gtatgtctga aatgggcttt ggtatgatgt tcggaagcga
    25141 tacacaaaaa caatttttct taaaacccat caagggaaga ggttacgtgg atacaggaaa
    25201 aagtgtgatt agtgagtttt atacacccct tgtaccaaaa aggtacgatt tcttaggaga
    25261 aataggaaaa gtcattcaaa aaaagcaatc tgagcctgta ccgcacgaag tgaaaggtac
    25321 aggttcagac ttgctttgat tggtgtggcg ttagccacgc caatccttta gccccctcta
    25381 tctaacaggg gggcacaaat acaactgaaa acaggcaatt ctcatcaacc aatgttgatg
    25441 gtacaaagga ttgcggaaaa tatgaaaggt gtaaactcaa gggtcatagt ttacatcttt
    25501 tttagattgg aggtttgcga atggaaaacg aaaaaatttg gattaaggaa ttgaaagaaa
    25561 agcgactggc ttatggcgtt tctcaaaata aactggcggt tgcttctcat attaccagac
    25621 cttacctatc ggatattgaa acaggcaagg cagtccctac tcaacaggtg aaagaagatt
    25681 tactgaacgc tttggaacgc ttcaatcccg ataacccatt ggagatgtta ttcgactatg
    25741 tacggattcg attccctacc aatgatgtgg ctcaaattat cggtgaggtt ttacgtttga
    25801 atatggatta tatgctacac gaagactttg gctattattc ttatcccgaa cactatcgtt
    25861 tcggtgatat tgttgtccta gtctctcatg atgtaagtaa aggtgtttta ttagaactga
    25921 aaggaaaagg ctgtcggcaa tttgaaaact ttctattggc tcaacatcgg agctggtatg
    25981 atttctttca agattgcatg gaacataaag gtattttcaa acgcttggat ttagctatca
    26041 acgataaaac agggattttg aatattccag atttggcaaa gaaatgtaaa caggaagaat
    26101 gcatttccgt ctttcgaagc tttaaaaatt atcgcagtgg tgaattggtt caccgtgatg
    26161 aaaaaccata catgggaaac acactttata ttggctcatt aaaaagtgaa gtctatttct
    26221 gtatatatga gaaagattat gagcaatacg tgaaaaatga tgttccctta gaagacgcag
    26281 aagtaaagaa tcggtttgaa attcggttaa aaaatgaccg agccacccaa gccatgaaag
    26341 atttattggc acatcaacag gcggaaaaaa cagcctttga aattatcaat cgctatatcc
    26401 gctttgcaga taaagacgac actaaacgtc ggagtgattg gaaaactaat gaacgttggg
    26461 aatggtttat cggtaaaaat cgtggagcat tacgcctaac cacacagcca gagccttatt
    26521 cttttgaacg aacattgaac tggttacatc atcaagtcgc ccctacatta aaaatcgcaa
    26581 gcattttaga tgttctcaac ggtacaacca ttatctccac catgattcag gaagccaaac
    26641 tgacagaaaa acatgagaaa ttaattgaac aacaacatct agccatggag gatttgatta
    26701 catgagcctt ttaacaaaag aattaaagaa gttagggttt cagtgtggca ttgagtttca
    26761 agcgtatata caaaatacag ggaaatatac gtctctcatt attgagggaa aacggcaagc
    26821 tggtgatacc atctatacct atgattttta caaggtgaga ttttataata attataccaa
    26881 tcgagtaacc gtctatggag agcatttaac cccttttcaa ttattaaggc gtgtaaaaag
    26941 ctatatctat tatcgagaaa aatatcttaa ggaaaggagg acaatcacat gaattttggg
    27001 cagaatttgt acaactggtt cttggataat gcacagtcat tggtattgtt agcgattgtt
    27061 gtcattggac tgtttttagg ttttaaacga gaattttcaa aactcattgg cttcttgatt
    27121 attgctctaa tcgccgtcgg acttgtgttc aatgcagctg gcgtgaaaga tgtgttatta
    27181 aacttattta accgaatcat tggtgcttaa cagatatttt tcatgataaa ataggaagta
    27241 tatattttgt tatgaaagga tttatgaata tgtttacaaa tgatcaattt aaatctcttt
    27301 taattaaaac attagaaaga aagagctctt caaattatta tgaaggaggt aacgagattg
    27361 tttctaaaat gaaaatatca gaggtaactt tagatgagac tgacgatttt acttattata
    27421 aaggatataa aaagggctgg aatacgcttt gcacatatct taaaataaga gttccttttg
    27481 atgatttaga cttttttgaa agtcataaag atttgattac ccagacagca agctccatat
    27541 atgataaaca aggtgataat gtattagtgg atactatttt agtaccactt ccagagaatt
    27601 acgaagtaat taactttagt cagttgaaaa ttagtgatgt ggtttcacaa gctattgaag
    27661 acgctgagtc ttttatgagt aatggtgaat atcaacgtgc ctttgacaga gttcacactg
    27721 cttttcatgg atatttaatt gaaatactaa aaaaatatga aattacagtt cctagagacg
    27781 aaaatctatc taaattatat agtaggatac aacaattaat tgaaaaagaa attcaaccta
    27841 ctgaacttgc tgatatagtg aagacaacga taaggtcatc aaatggaatg attagctctc
    27901 ttaatgaagc aagaaatagg cattcacttg cacaccctaa tacaaatatt attggaaaga
    27961 gagaagcaaa actaataata ggtatttcaa gtacagttac agattatatt agcggatacc
    28021 ttgataagta gcgtcattaa ctgattgcta ctttttttat gactattttt ataaaaagga
    28081 tgtgataaga attggaaatg aaagtctatg tggcaaattt aggacggtat aatgaaggtg
    28141 aattagtcgg agcatggttt actccaccaa ttgatgagga agaaatggca gaaagaatcg
    28201 gtttaaatga ggactacgaa gaatatgcaa tacatgattt tgagcttcct tttgatgtgg
    28261 acgaatacac gccgattagt gaaatcaacc gtctatgtga agccattcaa gaaatcgaag
    28321 gtacacctat ttataatgaa ctcaaagaaa ttcaaggcat gtggtttagt agcttggaag
    28381 aattactgga aaacaaagag gatattcatt gttatagtga ttgtgattcg atggaagatg
    28441 tcgcccgtta ttacgtggaa gaaacaggac agcttggtga agtcccttcc aatttacaaa
    28501 attatattga ctaccaatct ttgggacgtg atatggaaat agagggtaat tacctagtta
    28561 cctctcatgg ggtatttgaa tattgtcagt aagtttaaca atccgtgtta taattaaatt
    28621 aataaatagc acggagaggt ataaattatg gtaaatgtat ttgaaaatct taaactatta
    28681 aaactagaca tgaaagataa aggctgggtg atagattcct tttactttcg ttacaaacag
    28741 caaaattata ttgtacttgt taagctattt gaaaaagagg aaaaagttcc agaatatgct
    28801 ctgttaaaac tagaattttt aaaggaaaac gatttttcag atatgctagc tgtctatgct
    28861 aattcggtaa aattatatac agacacgaaa acaataagag aatattttgg tatcgaatac
    28921 agtagtaact tgggagatgt tttatttcaa tttagccaaa ctcttgctcg atttattccg
    28981 acagaagtta gtgagaagaa aaatgaagac caaaaagaag ccatgtgttt ctcattaagt
    29041 caaagtgatt cagaagatcc cagaaaaaaa tattgttttt cagttagaag aaatccttta
    29101 aagggaaatg gtgagctggg aaaacgaagt ccttttaatg acaataaaac gagattgtat
    29161 agacccagct tatatgaacg attagggtca gataccaatt taagtttcag atattcaatg
    29221 aatccagatg atgaagaaac tgatgaaggt attattgcaa aatggacaaa aaataaaatt
    29281 gaatagttaa agcattgaaa gagcaatcac ctattttgat tgttcttttt ctatttttac
    29341 ggaaaggacg tgaagacatg aaaaaaataa gaagttacac cagtatttgg tcagtagaaa
    29401 aagtgattta tgcgattaat gatttacaac tccctttccc aattaccttt acgcaaatga
    29461 catggtttat cgtttctttg tttgtcgtca tactctttgg cagtttacca ccactttctc
    29521 tgattgacgg agcactactc aaatacttag ggattcccat tgttctcact gggttcatgt
    29581 gccaaaagac ctttgacgga aagaaaccct atggatttct aaagtctatc attacctatg
    29641 ctctacgccc taaagtaacc tacgctggca aacaaatacg attaaaaaaa gaaacaatga
    29701 atgaatcgat tacgattgta aggagtgaac aactagatgg catatccgat taaatatatg
    29761 gaagataatc tcgtatttaa tcatgatggc gaagtattcg cttattatga attaattccc
    29821 tataattaca gttttttaag ttccgatgaa aaaattcaag ttcatgataa tttctgtcaa
    29881 ttgattgccc aaaatcgtga tggcaagatt catgctctgc aactagcaac cgaatcaagt
    29941 attcgagcca cacaggaaca atcgaaaaaa gaaatcactg gacgattaaa agagatagct
    30001 tacgaaaaaa tagatgaaca gaccgaagcg ttaatttcta tgattggtga caatcaagta
    30061 gactatcgct tttttattgg ttttaaactc tacctcaatg aacaggaagt atccgtaaaa
    30121 aatgttggga aagaaattca aaaagcattt gcggaattct ttcatggtgt gaatcacaaa
    30181 ttaatgggcg attttgtttc tatgcctatg gcggaaatcg aacgcttttc taagatggaa
    30241 cagttgttag aaagtaaatt atccagacgc tttcagattc gtaaattgga gaaagatgat
    30301 tttggttata ttattgaaca tctttacggg caaacaggtg tcccttttga tgactacgac
    30361 taccatttac cgaaacgata cgaagataaa aaagtgttgg taaagaaata cgatattctc
    30421 aaacccactc gctgtttaat cgaagaaaat caacgctatt tacggattga acaggaagat
    30481 accactactt atgtggcgta ttttacaatt aatagtattg ttggtgaatt ggatttccct
    30541 aatagtgaaa ttttttatta ccagcaacag cagtttactt tccccgttga taccagtatg
    30601 aatgttgaaa ttgtcgccaa taaaaaagcc ttatctaccg ttcgcaataa aaagaaagaa
    30661 ctgaaagatt tagatagcca cgcatgggaa agcgacaacg aaaccagtac taatgtggtg
    30721 gacgctttag aatctgtcga tgaattagaa agtaatttag accaaaccaa agaatctatg
    30781 tacaaactaa gctatgtggt acgggtatca gcaaagaatt tggacgagct gaaacaacgt
    30841 tgtgatgaag taaaagattt ttatgatgat ctgtctatca aattagtacg accttttggc
    30901 gatatgctag gcttgcataa tgaatttatt ccctcaagca agcgatatat caatgactat
    30961 attcaatatg tcacgtcgga ttttttggct ggtcttggtt tcggtgctac acaaatgatt
    31021 ggtgaaaatt ctggtattta cgtcggttac aatctcgata caggcagaaa tatttatctc
    31081 caacctagcc ttgcaagtca aggaattaaa ggctctgtaa caaatgcatt agcgtccgct
    31141 tttattggtt cattaggtgg cggaaaatca ttctctaaca atatgctggt ctattattca
    31201 gtactctttg gcggacaggc aaccattgtt gacccaaaag ctgaacgtgg tgaatggaaa
    31261 gaaaccttac ctgatattgc ccatgaaatc aatattgtta atctcacgag tgagaacgac
    31321 aataaagggt tacttgaccc ttatgtgatt ttaaaactcc cgaaagattc agaaagcctt
    31381 gccattgata ttctcacgtt cttaacaggt atttccagcc gagatagcga gaagtttcct
    31441 gtcctgcgta aagctattcg gagtgtaact caaagcaaac aacgagggtt gttattggtg
    31501 attgatgaat tgcgaaaaga agatacgccc atcagcaata gtattgctga ccatatcgaa
    31561 agctttgtcg attatgattt tgcccatctg ttattcagtg atggcagtgt cacccaatcc
    31621 attagcttgg aaaaacaact caatattatt caagtggcag atttggtctt acccgattcc
    31681 aatagctctt ttgaagaata cactaccatg gaattattaa gtgtggcaat gctgattgtc
    31741 attagtacct ttgctttaga ctttatccac tctgaccgtt ccatttttaa aattgttgac
    31801 cttgatgagg cttggagttt tttacaagtg gcacaaggaa aagctctatc tatgcgattg
    31861 gttcgagcag gacgtgccat gaatgcaggg gtctatttcg ttactcaaaa cgcggacgat
    31921 ttactagatg aaaagatgaa gaataatatt ggcttgaaat ttgcctttcg ttccactgac
    31981 ctagtggaaa tcaaaaagac cttagaattt tttggtgtgg acaaggaaga tgaaaacaat
    32041 cagaaacgct tacgtgaatt agaaaatgga caatgtttag tttcagacat ctatggtcgt
    32101 gtaggggtta tgcagtttca cccgattttt gaagagttgc ttcatgcctt tgataccaga
    32161 ccgcctgtgc gaaatgaggt ggaagaatga cacaaaaaca aaagaaattt cttcactata
    32221 gttggataac gctcctttgt gtgggcgtta ttttactttt attaggcacg ctgggcaatg
    32281 cagtacaagc gacaggctta gttgatgaaa ccattgatac aagcaatgaa tactccaagt
    32341 atggtttgaa tcaatatcag cttgattatt atgtggacaa tagctggggc tggcttccat
    32401 ggaattggag tgatggcata ggacaatcgg tgatgtatgg attgtatgcc attactaatt
    32461 ttatttggac aatttctctt tatctatcga acgccacagg ttatttggtg aaagaagcct
    32521 atgccttaga tttcattagt caaacatccc aagcaattgg cgaaaacatg cagacgattg
    32581 caggcattac accgaatggc ttttccagtt cagggtttta tgtcggtttc ctccttcttt
    32641 ttattctcat tgttggaatc tatgttgcct atacaggatt ggttaagcga gaaacgacga
    32701 aagtgatacg agctgtttta aactttgtcg tggtgtttat tctatcggct tcctttattg
    32761 cgtatgcacc cgattatatt gcgaaaatca atgatttttc caaagatgtc agtaccgcca
    32821 gtctgaatat tgggacaaaa attgttcttc ctaacacgga tagtcaaggg aaagacagtg
    32881 tggacatgat acgtgacagc ttattctctg ttcaagtaaa gcaaccatgg ctattgcttc
    32941 aatatggctc cactgatgta gaagcgttag gggaagaacg tgtggaaagt ttattgtcta
    33001 ccagtccaga tacaaacaat ggtgaagata gagaaaatgt agtgattgaa gaaattgaag
    33061 atcatgacaa tacctattta accctaccga agacgatttc cagattagga acagtcttct
    33121 ttttgtttgt attcaatatt ggtatctcga tttttgtttt ccttctaaca ggaatcatga
    33181 ttttttcgca agtgctattt attattttcg ctatgttttt gccaatcagt ttcctattaa
    33241 gtatgttgcc gagttttgat ggcatgggca ggcatgccat taccaagtta tttaatgtga
    33301 ttatgacaag ggctggtatt accttgatta ttaccgttgc ctttagtatt tccactatgc
    33361 tttattcgct gtcagcaagt tctccctttt tcatgattat gtttttacaa attgtgacct
    33421 ttgcagggat ttattttaaa ctgggcgatt taatgagcct attcacttta caaagcaacg
    33481 actctcaaaa catgggcaga caagtgtttc gcagacctcg tcaaatgatg aatcgacaaa
    33541 ccagaagatt tcaacgcagt atgagtaaga tttttcgtgg aaaagcaggg tcaacgaagc
    33601 aaaagacaat gacaacaaag cagaatcaaa ccaataaagc taaccatact cgtcaaaatg
    33661 aacggactac accaaagaaa gaaacagcac tttccaatgt gaaaaagcaa caaggcggta
    33721 tcgggcaacg attaggtgaa aagacagccc atgtattgga cacgaaaaat cgtctagtca
    33781 ataaaagaaa gcaggcaaaa caacagatac aggcgacacc aacccatgtc aaatatgccc
    33841 ttcatcaagg aaaagagaat gtcactcata atgtaacaga ctttaaacaa tctatggcag
    33901 ataccaaagc tcaacgcaaa caacagcgta tgaaccagca ggagcaaaaa cgaaagaaca
    33961 ttgctcaaaa gcgtttggag ctggataaag caaaagaaaa aagacgaaaa gaaaacccat
    34021 catctcctgt tcagaataac cagcagcatg ttcgcaagcg tcagcaaacc gtcacgcctg
    34081 ttttgtcaca aaacactaaa cgtgaaaatc atcagcgacc attgaaaaaa gagcaaaaac
    34141 aaaagacacc accgaagcaa ttcaatcaga ggaagctaaa taaaagaacg gataagcgag
    34201 gacaacaaac atgaagctaa aaataacagt gatttgtagt gtggtcttct ctctcttctt
    34261 ttttctctta ttattcctag tcattttctt tgcagatgat acggacagtg gcgaaaacaa
    34321 caaggattct tctattccac aaggcggtgt gaccgtttca ccagaagtgt tggcacaccg
    34381 tccgttgatt gaaaaatatg gtaaggaata tgggattgaa gactatgttt cttatatctt
    34441 agccattatg caagtggaat cgggcggtac agcagaagat gttatgcaaa gttccgaatc
    34501 tttgggttta ccgcccaaca gtttgagtac cgaagagtcc atcaaacaag gggttaaata
    34561 tttcagtgaa ttattaacca gtgcagaaca acaaggagtg gatatagatt ctgttatcca
    34621 atcttataat tatggcggtg gctttttaaa ttatgtgagg agtcatggga aaaaatatac
    34681 ctatgaatta gccgaacagt tttctaaaga gaagtcgggt ggtcaaaaag cagactatcc
    34741 caatcctata gccatacctg tgaatggtgg ttggcgatat aactatggaa atcagtttta
    34801 tgttcagttg gtttcacaat acctaaccga cacttcccca acagaatttg atggtgaaac
    34861 cgtgcaagtc attatggacg aagccttgaa atacgaaggg tttccctatg tctttggagg
    34921 ggcgtcgcct accacctctt ttgattgtag tggcttaata caatgggtgt atgacaaagc
    34981 tggcatttct ctccctcgtg tcgcccaaga tcagtatgac gctacgcaag aaatctctat
    35041 ggaagaagcc caagcaggcg acccaatcgg ttatggcgac ttaagcagtc gttattggca
    35101 agaccatctg attggggcta gacgtgttat tcataactaa gaaaggaatg aatcaaatga
    35161 ttataaaaat cgagcgaaaa gaaaagaagg agaaaccaaa gaaatctaaa aaaccgagca
    35221 agcaaagaaa agttccgatg attaaagttg gcacgcataa gaaattaacc tttgttttat
    35281 gggttttatt gattggtagt gtcggatttg gaatctataa aaattttact gccattgaca
    35341 ctcatactgt ccgtgaaaca gaaatcatta aacagcagat tgtcgatacc aaccaagtag
    35401 aaagttttgt gaaatccttt gcgaaagact acttttcgtg gcaacaatcc caagaagcca
    35461 ttgataaacg aaatgaaaaa ttgacccatt atttgacgga agaattgcag gtattaaatg
    35521 aagaaatgat tcgtaaggat attcctacta gttctagtgt gaacgatata caggtgtggc
    35581 aggtttctca agtgaatgag aacacctttg aggtactgtt ttctgttgaa caagttatta
    35641 ccgaagacaa agacaaggaa actatatcgt ctagctttca tgtggttgtc catatagatg
    35701 aatcagataa tatggttatt atcaaaaatc cgacaatgag taagaaacct caaaaatcgg
    35761 actaccaacc caaacagcta gaaagtgacc atacagtaga tacagaaacg atggacgaaa
    35821 tcactagctt tttagaaacg ttcttccagc tctatcctac cgccacagaa aaagaattga
    35881 cttactatgt aagtaatcat gtgttaccta tgattaacaa ggaatatgtt ttcgaggaat
    35941 tggtgaatcc tatctttacc agaaaagata accaagtaat cgtgaatgtc gctgtgaaat
    36001 atttagatca agaaacaaag gcaacccaaa tctcgcaatt tgagttgata ttagaaaaac
    36061 aagataattg gaagattgta aaataacaaa tattggtaca tgattacaga tactttgtaa
    36121 tcatgtactc tttttgataa aaaattggag attcctttac aaatatgctc ttacgtgcta
    36181 ttatttaagt gactatttaa aaggagttaa taaatatgcg gcaaggtatt cttaaataaa
    36241 ctgtcaattt gatagcggga acaaataatt agatgtcctt ttttaggagg gcttagtttt
    36301 ttgtacccag tttaagaata cctttatcat gtgattctaa agtatccaga gaatatctgt
    36361 atgctttgta tacctatggt tatgcataaa aatcccagtg ataaaagtat ttatcactgg
    36421 gatttttatg cccttttggg tttttgaatg gaggaaaatc acatgaaaat tattaatatt
    36481 ggagttttag ctcatgttga tgcaggaaaa actaccttaa cagaaagctt attatataac
    36541 agtggagcga ttacagaatt aggaagcgtg gacaaaggta caacgaggac ggataatacg
    36601 cttttagaac gtcagagagg aattacaatt cagacaggaa taacctcttt tcagtgggaa
    36661 aatacgaagg tgaacatcat agacacgcca ggacatatgg atttcttagc agaagtatat
    36721 cgttcattat cagttttaga tggggcaatt ctactgattt ctgcaaaaga tggcgtacaa
    36781 gcacaaactc gtatattatt tcatgcactt aggaaaatgg ggattcccac aatctttttt
    36841 atcaataaga ttgaccaaaa tggaattgat ttatcaacgg tttatcagga tattaaagag
    36901 aaactttctg ccgaaattgt aatcaaacag aaggtagaac tgtatcctaa tatgtgtgtg
    36961 acgaacttta ccgaatctga acaatgggat acggtaatag agggaaacga tgacctttta
    37021 gagaaatata tgtccggtaa atcattagaa gcattggaac tcgaacaaga ggaaagcata
    37081 agatttcaga attgttctct gttccctctt tatcatggaa gtgcaaaaag taatataggg
    37141 attgataacc ttatagaagt tattactaat aaattttatt catcaacaca tcgaggtccg
    37201 tctgaacttt gcggaaatgt tttcaaaatt gaatatacaa aaaaaagaca acgtcttgca
    37261 tatatacgcc tttatagtgg agtactacat ttacgagatt cggttagagt atcagaaaaa
    37321 gaaaaaataa aagttacaga aatgtatact tcaataaatg gtgaattatg taagattgat
    37381 agagcttatt ctggagaaat tgttattttg caaaatgagt ttttgaagtt aaatagtgtt
    37441 cttggagata caaaactatt gccacagaga aaaaagattg aaaatccgca ccctctacta
    37501 caaacaactg ttgaaccgag taaacctgaa cagagagaaa tgttgcttga tgcccttttg
    37561 gaaatctcag atagtgatcc gcttctacga tattacgtgg attctacgac acatgaaatt
    37621 atactttctt tcttagggaa agtacaaatg gaagtgatta gtgcactgtt gcaagaaaag
    37681 tatcatgtgg agatagaact aaaagagcct acagtcattt atatggagag accgttaaaa
    37741 aatgcagaat ataccattca catcgaagtg ccgccaaatc ctttctgggc ttccattggt
    37801 ttatctgtat caccgcttcc gttgggaagt ggaatgcagt atgagagctc ggtttctctt
    37861 ggatacttaa atcaatcatt tcaaaatgca gttatggaag ggatacgcta tggttgcgaa
    37921 caaggattat atggttggaa tgtgacggat tgtaaaatct gttttaagta cggtttatac
    37981 tatagccctg ttagtactcc agcagatttt cggatgctta ctcctattgt actggagcaa
    38041 gcctttagaa aagctggaac agaattgtta gagccatatc ttagttttaa agtttatgca
    38101 ccacaggaat atctttcacg ggcatataac gatgctccca aatattgtgc aaatatcgta
    38161 aatactcaac tgaaaaataa tgaggtcatt attattggag aaattcctgc tcgatgtatt
    38221 caagattatc gcaatgattt aacttttttt acaaatgggc ttagtgtttg tttagcagag
    38281 ctaaaaggat atcaggttac cactggcgaa cctgtttgcc agacccgtcg tctaaatagt
    38341 cggatagata aagtaagata tatgttcaat aaaataactt agtgcgtttt atgttgttat
    38401 ataaatatgg tttcttatta aataagatga aatattcttt aatatagatt tgaattaaag
    38461 tggaaaggag gagattgtta ttataaacta caagtggata ttgtgtccta tttgtggaaa
    38521 taaaacaaga ctacgaatac gagtggatac tatacttaaa aatttccctt tatactgccc
    38581 caaatgtaag aacgaaactt taattaatgt tcaaaaaatg aatataataa caatcaaaga
    38641 gccagacgcc aagacgcaga gccgataatt tgagaaatga aactctcatc ttatcggctc
    38701 tttttgttta tctgaatttt actgactagc cttcaatatt tcttgcttca ttgatacctt
    38761 ttgctagtgc ttccattaag gatagttctt tgtctgtaaa gctatccatg tatttttcta
    38821 cctgtaacct tcgagtgctt ttaatcaaat tatctgtagg taagaaaaat tcatcaatag
    38881 atacatggag taatgataca agatcataca gcacttgtgt acttgggtgt tgtcctttgt
    38941 tttctatatt tgttaaataa cgtgggtcaa tttcaatcat tgttcccact tgttcacgag
    39001 tgagaccccg tttcattcga gcctctttaa tcgctaaacc aacggctcta aaatcgtatt
    39061 tatcttcttt tttacgcata ctaaatcacc tctatacatt ttactgttcc tatataacca
    39121 taaacaggta tagaaaaaca tgttatatag tttatgagtt cctatagaac actgtggaat
    39181 ttattaatgc gatgaatcca atttcaaata gaaaggtcgc tgattttatt tacctataca
    39241 actttataaa atttagtcat actcctagaa agtagataaa attggcgact taatggaggg
    39301 aaaagtcgcc atgagaaaga taatctgtca tctagttctc ttaattaagt tcttatcaaa
    39361 aaaacttatc cacctgtact ggatagatat gaccatcaat gtggttttgc agattacata
    39421 gatagaaaaa tcaaagcata tgaacagaga aaacaatctg tttatgtgct tttttggtca
    39481 cttaataaat atcttttagg atttctcttc atttatgcaa caaatccccc tttcgtgtcg
    39541 gggtttagta tgaagggaga taaagaagca catgccactc cctttcacga cagaaagggg
    39601 gtgaaaagca tgaaaccatc ttcttttcaa gaaaccatag aaaatcagtt tgactatatc
    39661 tgcaaacaag ttattgaaga tgaacgaaaa gattacttca aacatctaga cagactatca
    39721 gcaaaagaag tctcgttttc tgatatagat aactaccttg tcaactcttt ttctactgtt
    39781 gatacgtacg tcactgattt ccaactattt aaattatttg gattaagaat caatgttgaa
    39841 agtgatttat taagtgaagc cctgcgtcat ctttcagaga aaaaacggaa cattatttta
    39901 cttcattact ttatggatat gagtgatgtg gagattgcgg agttactaaa tttgaatcgt
    39961 tcgactgttt atcgtcatcg aataagtgga ctagccatga ttaaagaatt catgaaggag
    40021 tgtaaagaat gaaaacagct tatccaaggg ttcccttccc cctcattgta aaggcgacag
    40081 atggcgacgt ggaagcaatt aatcagattg ttaaacatta tcgagggtat acctcaaaac
    40141 gttcattacg tcgcatgaca gacgaatatg gaaattctca tatggttatt gatgaaaccc
    40201 tacgtggcag aatggaaacg aaactcatct ctaagatttt atcgttcgaa attaaatagt
    40261 cccatttttt cgtggaagcg tgtcgaatcg tatccacgct tcccgatttg ggaggtttgt
    40321 tattccatca aagcatattg tgtgttcagt aggttttgat aggctaacaa gccaaacgtt
    40381 ctttgacaac caaataaagg caatcgaata cgtttcggta agaaaagagc tgatgaacta
    40441 acacgccatg acctacaaaa ttagtgagcg attcatgtta gtaattcgaa agtaatcttt
    40501 agcaggattg ctgccatgac tttcttatcg tgataatgat actcccgtat agccatagtc
    40561 cgagcgttag aagcgtcaca ggcaatgggt acggctacat gagaaccatg cagaagtgaa
    40621 attcctgtga gctttgctag agctgttcga ttgctaagat attcttctct tgtcagtgta
    40681 ttattataaa actatttgat ataattatag gtgaatattg gagttttcct agcctataat
    40741 tgggaaagga gtaataatga taacggtcac aaaaaaggat ttagttgagc taggatatgg
    40801 aacttctttt tcagcagaca tcataaaaaa agcaaaagaa ttgatgatta caaaagggca
    40861 tatctactat caatctcgaa agctagatag agtccctcgt gaagctgttg aagaaattct
    40921 aggaattcgg ttttcaaatg aaaacaggtc tgagtagttt ttgcacagta aggagtaaaa
    40981 actatggtta aagacccaat aaaaaaagca aagaatggaa cctattattt tcgtgcaaat
    41041 ctaggttatg attctaaagg gaaaaaaatt caaaaatatc gtagtggatt cactactaaa
    41101 aaagaagcaa gagaagaata ttcgaaactg ctattgatga aaccagaaga attaagtgag
    41161 aataaggata aaatgacgtt taaacattat atctttgaaa ttttccttcc atggtataag
    41221 acacaggtaa agctcagaac atatgaaaat cgcttaccaa ctattaagaa gcatttctct
    41281 tattttgata aaatggctgt ttccgatatt gagcctattg atgtgcaaaa ttggcaacta
    41341 aaattatcaa agaagtgtaa gtcttcttat gtaagagctg ttcaaggact attttcagtt
    41401 gctatggatc gagcaattgt ccttgggata accaccacaa atccatctaa gattattggc
    41461 aatgtgaaaa agcaaaagtc taaaattgaa ttttggacaa aagaagaatt tgaaaaagta
    41521 atctctctaa tttacaaaga agattactat caacactttt tatttatctc tctgtggttt
    41581 ttatttatga ctggaatgcg aattggtgaa gctactgcca ttcaatggga agatattgat
    41641 tttgactcag gagtactaac catcaacaaa acactctatt acaagaatca atcgaattat
    41701 agatttgttg aaccaaaaac aaaggcgagc gttcgtcata ttgtattaga taaatgcaca
    41761 ttaacttatt tatccgaatg gaaggaagta caacaaaatc taattcagac agactttgta
    41821 atgagctata acggtattcc tacccaaaaa catacactat catatgctat tgaacgctat
    41881 gctaagctgg ctggtatcca tcgaatcaga atccatgggt tacggcattc tcatgcttcc
    41941 ttgttaatca gtatgggaga aaatccactt atcattaaag atcgtctagg acacgaagat
    42001 attgagacga ctttaggaac gtatggacat ctttatccta acagtaattt cgaggtagct
    42061 aacaaattaa atggagccat ttcctttaaa gaagcaaaac aaaattatga tacttcacca
    42121 aagaatcaat ttactgtaga ctacttgcga aacaaagaaa tgaaaaaagt gcaataaaag
    42181 tgcagtaaaa agataagaag agccagaaac ccttggtata agaggatttc tagctctcct
    42241 acaactattc ccactccact gttgctggtg gtttagaagt gatgtcatac acgatacggt
    42301 tgacgtgggc tacttcgttt acgatacgta cagagatttt ttgcaagact tcccatggga
    42361 tacgggcaaa gtcagcggtc attccgtcga ttgaagttac agcacggata ccgactgtgt
    42421 agtcgtaagt acgtccgtca cccataacac cgacagagcg gatccctgga agaacagtga
    42481 aatattgcca gatatcacgg tcaagtccag cagctgcgat ttcttcacgc aagatagcat
    42541 cagattcgcg tacgatttct agcttgtctt cagtgatttc gccaagaaca cgaataccaa
    42601 gaccaggacc agggaatggc tgacgccaaa cgattgaatc aggcatgcct aactgagtcc
    42661 ctaattcacg gacttcgtct ttgaataatg tgtttaatgg ttcgatcaat tcaaattgca
    42721 tatcttctgg cagtccacct acattatggt gagatttgat cgtctgtgct gtttctgtac
    42781 cagattcgat aacgtcagta tacaacgttc cttgtgctag gaaagagacg ccttcttcac
    42841 cagcaagttt tgttgcttcg tcatcaaaaa catatacgaa ttcattccca atgattttac
    42901 gtttttgttc tgggtcagat acacctttca acttgtctaa gaagcgatct cttgcatcga
    42961 ctttgatgat gttcaagccg aattttccgc ctagactttc cattacttgt tccgcttcgc
    43021 ctttgcgtag cagaccgtgg tcaacaaaga tagatgtcaa ttggtcaccg atcgcttttt
    43081 gtaaaagaac cccaacgaca ctagaatcaa cgccacctga aagaccaagc aagacttttt
    43141 tgtcaccaac ttgttcacgg attttttcta cttgcatatc gataaagtta tccattgtcc
    43201 agttaccttc acagtgacaa acatcaaagg caaagtggcg cagcaattcg attccgtatt
    43261 cggaatgacg tacttctgca tggaattgga taccataaaa attacgtgtt gtgtcttgga
    43321 tagaagcaat cggacaatct ttgcttgttc cgactgtttc aaagccttca ggaactttag
    43381 ttaccaagtc accatggctc atccatactg tttgttgttt tggtgtttct ttaaacaaga
    43441 cagcttgatc gcttgttact tctaacaagg ctttcccata ttcgcggttt ttagcaggct
    43501 ctacggaacc gccaagtttg tacgtgatca attgcatacc atagcaaatc cctaatacag
    43561 gaatacctaa attgaagatc tcaggatcga tcccaaatgc attctcatca tatacactgt
    43621 ttggtccgcc agaaagaatg attccctttg gattcatcgc ttttacttct tctgcagtaa
    43681 tgcggtggct caataattcg gaaaagactc caagatcacg aatacgtctt gtgatcaatt
    43741 ggttatactg actaccgtag tctaatacga taatcttttc aacgttcgtc atatcggcaa
    43801 cgtttgtcaa atttattacc cctatccctt taaattttat ctcaaaatag tcaaactatt
    43861 ttaaaatgct aatattttcg catgaaaatc gaatcgatga tatgattttc agttttatgg
    43921 agaattatat cggctcttcc tcgtgtaggc aagatatatt cctgtaaatt tttcaaattc
    43981 acatttttcc atacatcttt tgccatttta aaggcttctt cacgatctcc gatagcaaaa
    44041 cgataataat aattctctgg attttggaaa gccgtatcca gtaacgcacc aaaacgatcc
    44101 aaataccatt tttcgatcag cacgggatcg gcatcgacat agacagaaaa atcaaaaaag
    44161 tcgctgacgt agatttgctg attcgcaggt aattgaagcg tattgatccc ctcaacgatc
    44221 aagatatcag gctgctggat caattcgtac ttgtctggaa tgatatcata cacatcatgt
    44281 gagtaaacag gtacttttat ctcttcctga ccagatttta cacggttcaa gaaatcgatc
    44341 agcatctcca tatcataact ttcaggaaat cctttacggt ccatgattcc acgctctttt
    44401 aatatacgat ttggataaag aaatccgtca gtcgtgatca gctgaacgtt tcttcgtttg
    44461 aaggtacgag acaaaatcgt ctgcagcagt ctggctgttg tactttttcc aacggctaca
    44521 cttccggcga tcccgataat aaaaggcggt acttctacgt atttatgaag aaataaacct
    44581 ttactcaaga acaaagattc aaattctttc atataaagat aaatcagatg agcaagaggt
    44641 acatagatat ctcgaacatc ctgcatggaa atgcggtcat tcaaactttt gatattatct
    44701 agttcatctt gtgtcaaagg tgcttgccca ttacgataaa attctcgcca ttcttctctt
    44761 gccacacggt agtagttcat tggatcattc atattagcct cctgcgttct cccatcaatg
    44821 gaactatttt aacacaaaat aaacgcaaac cccaccactt aagagagatt gccgatcttt
    44881 ttgtataatc tttataatag aaagaaacgg agtcttattc ttgacttgcg cacggataca
    44941 taaaaggata gactgttgtc atgaaagaaa tgagaaggat ggaagacatg acaaatcatt
    45001 actattctga acgcccagat acggcgcacg attttgaaca atgggctttt gagttaaaag
    45061 gcagaacctt tcaatttgta acagattctg gtgtattttc acgtgaaaca gtggattatg
    45121 gttcacgtgt cctgattgat gctttcgatt gggaagagtt acctgatgaa ggaaagatct
    45181 tagatgtggg atgcgggtat ggaccgattg ggttagcttt ggcatttgcg acacagcggt
    45241 ttgttgaaat ggtcgacatt aatgaacgag cggtaagtct agcgcaagga aacgcaaagc
    45301 gtaaccaaat cgaacatgtt gatatccatc aatcgaatat ctatgaagca gttcatgaag
    45361 aaacctatgc agctatcgta agcaatccgc cgatccgtgc tggaaaaaaa gttgtacatg
    45421 aaattttgac aggcgcatat cctcggttga agaagggcgg tacactgaca attgtgatcc
    45481 agaagaaaca aggagcgccg agtgcgcaaa agaaaatgga agaaacattt ggtaatgcag
    45541 aaatcgtcac aaaagataaa ggatattata tcatcaaaag tgtgaaagaa taactagctg
    45601 aaaaa
//
LOCUS       DAFEIE010000016        44720 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFEIE010000016
VERSION     DAFEIE010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.016"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="LP345_000992"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="LP345_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL1759793.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="LP345_000993"
     CDS             complement(323..892)
                     /locus_tag="LP345_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBL1759794.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="LP345_000994"
     CDS             1078..1980
                     /locus_tag="LP345_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1759795.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="LP345_000995"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="LP345_000995"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBL1759796.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="LP345_000996"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="LP345_000996"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBL1759797.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="LP345_000997"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="LP345_000997"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBL1759798.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="LP345_000998"
     CDS             8548..8733
                     /locus_tag="LP345_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBL1759799.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="LP345_000999"
     CDS             complement(8795..9991)
                     /locus_tag="LP345_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL1759800.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="LP345_001000"
     CDS             complement(10161..11597)
                     /locus_tag="LP345_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL1759801.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="LP345_001001"
     CDS             11890..12699
                     /locus_tag="LP345_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1759802.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12885..15038)
                     /locus_tag="LP345_001002"
     CDS             complement(12885..15038)
                     /locus_tag="LP345_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBL1759803.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTSAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15433..16281)
                     /locus_tag="LP345_001003"
     CDS             complement(15433..16281)
                     /locus_tag="LP345_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1759804.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16505..18445)
                     /gene="thrS"
                     /locus_tag="LP345_001004"
     CDS             complement(16505..18445)
                     /gene="thrS"
                     /locus_tag="LP345_001004"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBL1759805.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18782..18961)
                     /locus_tag="LP345_001005"
     CDS             complement(18782..18961)
                     /locus_tag="LP345_001005"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBL1759806.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(19008..20831)
                     /gene="cadA"
                     /locus_tag="LP345_001006"
     CDS             complement(19008..20831)
                     /gene="cadA"
                     /locus_tag="LP345_001006"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL1759807.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            21109..23388
                     /locus_tag="LP345_001007"
     CDS             21109..23388
                     /locus_tag="LP345_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1759808.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23481..24128)
                     /locus_tag="LP345_001008"
     CDS             complement(23481..24128)
                     /locus_tag="LP345_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759809.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24307..25026)
                     /locus_tag="LP345_001009"
     CDS             complement(24307..25026)
                     /locus_tag="LP345_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1759810.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25157..26308)
                     /locus_tag="LP345_001010"
     CDS             complement(25157..26308)
                     /locus_tag="LP345_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBL1759811.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26525..27265)
                     /locus_tag="LP345_001011"
     CDS             complement(26525..27265)
                     /locus_tag="LP345_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1759812.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27269..27592)
                     /gene="rsfS"
                     /locus_tag="LP345_001012"
     CDS             complement(27269..27592)
                     /gene="rsfS"
                     /locus_tag="LP345_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBL1759813.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27649..28242)
                     /gene="yqeK"
                     /locus_tag="LP345_001013"
     CDS             complement(27649..28242)
                     /gene="yqeK"
                     /locus_tag="LP345_001013"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBL1759814.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28226..28876)
                     /locus_tag="LP345_001014"
     CDS             complement(28226..28876)
                     /locus_tag="LP345_001014"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBL1759815.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28886..29197)
                     /gene="yhbY"
                     /locus_tag="LP345_001015"
     CDS             complement(28886..29197)
                     /gene="yhbY"
                     /locus_tag="LP345_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBL1759816.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29213..30322)
                     /gene="yqeH"
                     /locus_tag="LP345_001016"
     CDS             complement(29213..30322)
                     /gene="yqeH"
                     /locus_tag="LP345_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBL1759817.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30319..30846)
                     /locus_tag="LP345_001017"
     CDS             complement(30319..30846)
                     /locus_tag="LP345_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBL1759818.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(31026..31811)
                     /locus_tag="LP345_001018"
     CDS             complement(31026..31811)
                     /locus_tag="LP345_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBL1759819.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31804..32673)
                     /locus_tag="LP345_001019"
     CDS             complement(31804..32673)
                     /locus_tag="LP345_001019"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBL1759820.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32674..34053)
                     /locus_tag="LP345_001020"
     CDS             complement(32674..34053)
                     /locus_tag="LP345_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBL1759821.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(34061..34480)
                     /gene="fabZ"
                     /locus_tag="LP345_001021"
     CDS             complement(34061..34480)
                     /gene="fabZ"
                     /locus_tag="LP345_001021"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL1759822.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34505..34981)
                     /gene="accB"
                     /locus_tag="LP345_001022"
     CDS             complement(34505..34981)
                     /gene="accB"
                     /locus_tag="LP345_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBL1759823.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34984..36219)
                     /gene="fabF"
                     /locus_tag="LP345_001023"
     CDS             complement(34984..36219)
                     /gene="fabF"
                     /locus_tag="LP345_001023"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBL1759824.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36238..36975)
                     /gene="fabG"
                     /locus_tag="LP345_001024"
     CDS             complement(36238..36975)
                     /gene="fabG"
                     /locus_tag="LP345_001024"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBL1759825.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36987..37904)
                     /gene="fabD"
                     /locus_tag="LP345_001025"
     CDS             complement(36987..37904)
                     /gene="fabD"
                     /locus_tag="LP345_001025"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL1759826.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(38011..38235)
                     /locus_tag="LP345_001026"
     CDS             complement(38011..38235)
                     /locus_tag="LP345_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL1759827.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38288..39250)
                     /locus_tag="LP345_001027"
     CDS             complement(38288..39250)
                     /locus_tag="LP345_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBL1759828.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39260..39700)
                     /locus_tag="LP345_001028"
     CDS             complement(39260..39700)
                     /locus_tag="LP345_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1759829.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            40006..40971
                     /locus_tag="LP345_001029"
     CDS             40006..40971
                     /locus_tag="LP345_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL1759830.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(41028..41258)
                     /locus_tag="LP345_001030"
     CDS             complement(41028..41258)
                     /locus_tag="LP345_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBL1759831.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41344..42231)
                     /locus_tag="LP345_001031"
     CDS             complement(41344..42231)
                     /locus_tag="LP345_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBL1759832.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42320..43543)
                     /locus_tag="LP345_001032"
     CDS             complement(42320..43543)
                     /locus_tag="LP345_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1759833.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43560..44606)
                     /locus_tag="LP345_001033"
     CDS             complement(43560..44606)
                     /locus_tag="LP345_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1759834.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
BASE COUNT        12647 a         9672 c         7747 g        14654 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaatttt tgtcacaacc ttttttgccg agtaaacggt gttcaaaagc
    12781 cagtttctcg gtatgaagtc aaatttaagc aaaaatgtga gaagctattt tcacaaaatt
    12841 tttcttcata ctcgaaacta agcggctttt tcacgacctc ttttttattt tgccatgaac
    12901 atatcataat acgcgtccat tatttcttta gcaatcgtca agtttatgtg gtcttgttcg
    12961 tctaataagt tcggcaagac aacactgatg gcaatttccg gattgtctgt tggtccgtat
    13021 gccacgatat tactattgac tgtcgcaata tctggatgac cttccgcaac cgtttctgca
    13081 gtccctgttt ttgcggaaag gtccattttc gcactggcta atggtttggc tgatgtgtaa
    13141 ggatcggtac catggacaac ttggtggaat ccttcacgga ggatcgccat attttctgca
    13201 gaaatattga ccgtattttc tactgttgtg ccaatttctt tcttcacttc acccaagttt
    13261 ccattttcgt cattgccata gatcgctttg actaggtgcg gctgtactcg tttcccgcca
    13321 ttagcgactg ttgaagcata ttgagctaat tggattggtg tatatgtgtc aaactgtcca
    13381 aatgccaaat cggtaaagtt acctggagca taccattctt tgccattatc cgcattgaac
    13441 ttcttcatat aatcaacaga acgtgagatc ccaggagatt cattcggcaa atcgatccca
    13501 gtcgttgtac caagaccaaa ctctttgaaa gagtctctca attgctgata agctttagct
    13561 tcttcatcta aactaggtag tcccattcca ggtgtatagt ctagtcctaa catctttaac
    13621 gccactttga tcatatacgt attagaagac aattccgatg ctttgactgc atcaagagca
    13681 acttgtccgc ttcgattaaa gacagagctt ttttctgaag caccttgcag acgaatcggc
    13741 tcatcaatca aaacttgatt tccgctgatc gcgttacttg cccagcctgc tgtcaaagta
    13801 ccagccttga ctacagaccc tggatcaaag gcgctagtaa tcgtgcctaa agcattctcg
    13861 gtgatttctt tggaaccttg ttcatgactg aaaccagtca ttgctagcac ttctcctgtc
    13921 tgaggattca tagccactgc ataagcacca ggcgaatact gtgctttgcc gttgttgatc
    13981 aatgtttgat aattcctttt caaaatttct tctacttttg attggaattc tgcattcata
    14041 gataacatta aattagaacc tttttcccca gagaagattt ctttttgatt cgaaacattt
    14101 ccttcattat caagggaaac ttcatattgg gttttggttc cttgcaggac atcttcatat
    14161 tgtttttcca aataactttg tcctacacgg tcattccgag aataaccttt tgctaggtat
    14221 ttctctgctt catctgctgg aagtccttgc ttttcagtcg tcacactgcc aagaatactt
    14281 ttcagtgaac ttgctgcatt atattctcgt gtccagtctg tgccagtcga aactcctgga
    14341 agttcagaag cgcgttctgc cacaacagct aactcttgat cagtaacacc agagtttttg
    14401 atatagacag tgtttaattc atatgcacta ttcatccgtt taaagatggt agcaattttt
    14461 aattgctcct cgtttaaatt aatctcatca gctgtgactt tattgaccat cgcactatat
    14521 tgttcgctgt tccctaattg cttttctttt gccgaaagtc tttttgtggc ttctttcaaa
    14581 tgtttgggat cagccagcca aaaatctttt ttatctctat ctgtcagatt ttcatctacc
    14641 ggaacatcga tcagcgagtt cagcttcgtt gcgatttcaa gcaaatcttt agccgtaact
    14701 tgtgttcctc tcgtatatgt gatggcctga ttcgctttat tcgtaactaa agcttttcct
    14761 gtggagtcgt agatcattcc gcgaggagta ctttcttgga ccgtaatcgt agaagtagac
    14821 ttcactcgcg cctccatctc ttcgccgttc acgatctgca aataacccaa tctagcaatc
    14881 aacgcaacaa ataacgtaaa tataatgaaa aaaagaaaat ttaagcgaaa aggaacatgg
    14941 gaccggcgaa acgttttgtt cttaggttct tgtgcacctt ttcttatttt ttctaaccaa
    15001 gaagtattta atattttttt cataaaatct ttcatcattt cctatccttc cgcctattta
    15061 cattcatgct tcattgtacc caaaaacttc ttaataaaca agaagtattt aatatttttt
    15121 tcataaaatc tttcatcatt tcctatcctt ccgcctattt acattcatgc ttcattgtac
    15181 ccaaaaactt cttaataaaa aagaaaaaat gggcggagca agaaattctt tacctaattt
    15241 caagataaaa tcaacttttt gtttcacagc aatcacttaa agttacatat ccaactattt
    15301 ttttcattaa aaaataaact tatttttgaa aattatgttt tcttaagtcg tgaaacactt
    15361 tgatggatca tttatttgtg gaaaactacg ttttgttatt ctaaaaaact tatataaaaa
    15421 atagtaaggt ttttatttcg aatccataaa atattcttgg attgcttctc gtgttttttt
    15481 cactttttcg ctaagctttt cgtttttagc catatagaaa taaaaaatga tatcgatcgt
    15541 agcaaattgg gccaaaagtg aattagttgc cgcacttcga ttcgtgattt cttttggtct
    15601 agatgtttgt acgagtacat cggctatctt gctaagcggg ttatttccaa attgcgtcaa
    15661 cgcaatgatt tcgatattca tgcttttcgc cagctcggct aatgcgacta catctgcact
    15721 tctacctgag tttgaaacaa gccaaagcac tttctttttc tcattgctga caagttgcgg
    15781 gagcaagacg tggatatctt tttcaaaaat gattggctta ccgacacgag accatttttg
    15841 cagaatatct tctactacta aagaagaggc gccaacccca tataaaaaaa cagtctctgc
    15901 cgattccaaa cactctacga ctttttggat cgtttcttct tctagaatat ctactgtttc
    15961 ttttatcgct acttgtgcat tgttaccaag tttgtttttg atagagtaaa aggactcatt
    16021 tgcttctata tcactaaaac cttcatcgat tccagtctgt agttctgttg aaatcgtgat
    16081 tttgaagtcc gtcagacttt gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc
    16141 actcaacccg gaagcttctg ctaattcatt agctgtcatt gtagggacct tctcaatatt
    16201 accgataatg tagttggcca actttttttc tgctgaagaa taatcttcca tcatactttc
    16261 aatacgacta attacgctca taagttcctc caccctttta atgatagtct atgtaagtat
    16321 accatatcag acccttattc acggtcgtat actggataaa aaacaaaaaa acaatccgcc
    16381 caacagaata tcttatccca tcaatcccac agattctatt gagcatctgt gtctttgagg
    16441 aatacctgtt atctattgtt cggattgctt tctatctact acttttttac aggaaattta
    16501 cctattagtt ttctctgctg taatttttga cttctgcttc catagcatca ataaagatat
    16561 tcaaatcttc tacagctgtt tctttacttc cataacgacg tacgttcact gttgcatctt
    16621 ccaattcctt gtctccaaca actaattggt aagggatctt ttgtgtttga gaggcacgta
    16681 tcttatagcc cattttttca ttacgatcat caacttctac acgcaacccc ttcatttgca
    16741 aacgttcttt gatttcataa gcataatcgc catgtgcatc aacagaaaca gggatgattg
    16801 ttgcttgtat aggtgccaac catgttggaa aagcgccttt gtatacttct gttaaataag
    16861 cgacaaaacg ttccattgta gaaacaattc cgcggtggat aactactgga cgatgcgtat
    16921 tttccccgtc ttctccaaca tatgtcaaat caaagcgctc tggcaataag aagtctaatt
    16981 gtatagttga taatgtttct tctgtaccaa gagctgtttt gacttgaaca tctagttttg
    17041 gtccgtaaaa ggctgcctcg ccttctgctt caaagtaatc tagttctaat tcatccatag
    17101 cggctttcag cattgcttgg gctttttccc acattgcgtc atcatcaaaa tatttatctg
    17161 tattgtttgg atcgcgatag ctcaagcgga aacgataatc tgtaatattg aagtcagcat
    17221 atactgccac catcaattca agcgtacgtt taaattcatc tttgatttga tcaggacgaa
    17281 caaatgtatg accatcattc aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac
    17341 ctgatttttc atagcgatgc atcattccta attcagcgat acgaattggt aattcacgat
    17401 aagaatggat cgtgtttttg tagaccatca tgtgatgagg gcagttcatt gggcgaagaa
    17461 caagcatttc gccatctccc atatccattg gcgggaacat gtcttcttga taatgatccc
    17521 agtgtccaga tgttttgtac aactcaacat ctcccattat tggtgtatat acatgttggt
    17581 aacctagact aacttctttg tctacgatat aacgttcgat cgtgcgtcgg attgttgccc
    17641 cttttggaag ccagaatggc aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa
    17701 gttcttttcc tagtttacga tggtctcttt cttttgcttc ttcacggaga cggatatatt
    17761 ctttcaaagc tttcttgtca aaaaaggctg tcccgtatac acgttgcatc atttgattgt
    17821 ttgagtttcc acgccaataa gcacctgcca ctgataataa tttaaatact tgtatacggc
    17881 cagtggatgg aacatgtggt ccacgacaca aatcgatgaa ttcgccttgt tgataagcag
    17941 taatcacttc ttcttctggc aattcactaa tcagttctac tttgtacgga tcacttgcaa
    18001 aaatttctaa tgcttcctgt tttgaaagaa cacggcgttc gatcggcaga ttttctttga
    18061 cgattttcat catttctgct tcgattgccg gcaaatcttc tgcagttact tggttttgtc
    18121 cattatctgt atcgtagtaa aaccctgaat cgatagctgg tccaacgcca aagtggatat
    18181 ttggatagag gcgacgcatg gcttgggcca tcaaatgagc tgctgaatga cggactaagc
    18241 caagtgcatc ttcatggtct ggtgtgatga tctcaatact tgcatcttcc tcgattggac
    18301 gagtcaaatc aacgagtttt ccgttcactt taccagctaa agcttttttt gctaagcttt
    18361 ttgaaatgct ttcagcaatt gccaatgttg ttgttccaga ctcaaattct ttgactgcac
    18421 catctggaaa agtaattttt atcataatag tttcctcctt gaaatgtttt gattgatcag
    18481 atcatcaagc tgaaaaacaa aaaaatccta gcatctcttg aaaagagata ctaggacgaa
    18541 aagttcgtgg ttccacctaa tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc
    18601 cgaccgccct tgcttcaaca agggtttcga aagtggtcat cctttggttt tctcctggaa
    18661 aagtttcagc ctagcttttc ctctcttatc gaagactctc aaattcagtt ggctttctca
    18721 tcaatcaatt atgtgtttat ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa
    18781 cttatttttt ccattcccca tttacaccgt atgttccttt tttcatctca ttgatgatga
    18841 catggatgtg ttcttttggt gcctgcgtgt ttttatgaac agcttccgtg atatctttca
    18901 tcatattttc taattgttcc ggactgcgac cttctactaa ttcgacatgt acgaatggca
    18961 taatgctctc tcctctttct gatcgttctt ttttcaactc gattctatca tactatgttt
    19021 gtcttgggta ctgaatcagg aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa
    19081 atagagaccg tatccacgac ttcttgcaaa acagctccga ataatgcggg gattagtccc
    19141 gtacttgcaa ttaacatcaa aaaaatacaa ataaagatgc caatcagtac agactgtttc
    19201 gctattctca tcgtatctct tgaaatcact actgcttttg ctacacgcaa gagatcatct
    19261 ttcaagatga ccgcatctgc actttcacta gcagctgtag aaccatgagc ccccattgca
    19321 ataccgatat ctgcagcagc aagtgctggt gcgtcattca cgccgtctcc taccatcgca
    19381 acaggtcttt gatctttagg gatactttct aaaatggtca gtttatcttg aggcaagcta
    19441 cgggcatgta cagaatctaa ttggactttt tctgcaatcg tttgagcaat ggcagatcca
    19501 tccccggtga tcatcatcaa atttttcaca tcaagttttc ttagctcctt gattgtcttt
    19561 gctgcttctg ggcgaatctg atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt
    19621 gttacataga ttgctgtatt ggacgtttct atttcttcag ctgaaacaaa agaggcacgt
    19681 ccaatcttta cttcatgatt attgactact gcttggattc cttgaccggt cacttctttc
    19741 agttgactaa caggatacag ttggctgttt ttcacgttgt tcactaacga acgagctaag
    19801 atatggctag attcctgttc tgcactagct gcatacagaa gtagctcttc tttttttatt
    19861 ccattgactg gctgaatcgc ctctacttcc aatatccctt tggtaagcgt tcctgtttta
    19921 tcaaaagcaa tcgtttttgt acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg
    19981 atcccgtttt tacttgaacg gctcattcct gcaactaaag caatgggcgc agctagaatc
    20041 agtggacaag gtgatgccac taccagtacc tcagcaaatc gtaaagggtc ttttgagaac
    20101 caccaagaaa taccaccgat caaataagca atcaacgtga aagggactgc ataacgatca
    20161 gctaaacgga caaatcgggc aggcttttct tttgattctt cgactagttt aataatcatt
    20221 tgatactggc tgtctgcggc acgtttttca gcgatcattt ggatcgatcc gtctccattt
    20281 aaagaccctg acataatctg atctccaggt ttcttggttt ccgggcggga ctcacctgtc
    20341 aaagaagatt catcgaccga agattctcct ttggtcactc gaccatctgc gggtacaagt
    20401 tcgccaggct tgactagtaa ctggtcatca atatttattt catcgattac tatatcctgc
    20461 aattttcctt ctttgaatcg atgggcaatt cttggggtgt tatctaacaa agactgcagt
    20521 tctttacccg ctcgtttatt cgcgtaatcc tctagactat ctccgcccgt aagcatgatc
    20581 aatatcatca aactagccca gtattctttg acggctaatg ttgcaaggat tgcggtaatc
    20641 gctaatacat ctacgccata tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc
    20701 aagaaggcga gaatccctcc agtaaatgcg acaatcgcaa atgcaagggc cggctggtga
    20761 aaaacaaatt cacttaataa agctatccca ccaataagca aagtaagtaa aaattttttg
    20821 aaatgtgtca ttgttttttc tcctctttta tgtgacttag agaggttagt aataaatttc
    20881 cagctgcctc tttcatctta agcatagtcc ttgactagca ctttttaaaa caataggcct
    20941 taattgaaaa caactatcac tatcagcgtt tccaaaattc atcagttcta caaacaaaaa
    21001 tattcagcaa ggattacttt ttcgattcat cagttaaaaa gtaccttttt tcgaaaaact
    21061 atgctatact tttaattcgt tatttacggc ggaaggagca aacatgcgat gaatgagaaa
    21121 caactagaac aaacgcacgt ggatgaaacg atcgaactaa tccagatcga acaaaatatg
    21181 ctggatacaa aacaacaaga attgactcag gaaatgaatc attcgacaaa agacacagct
    21241 aatcacaaga ttcgagctgg ttccaatgaa gctttttatg aatctgctgt tgaatatcgc
    21301 caacatgagc aggaattgct tttgaaatac catactcttg aagcacagca aaaacgcctg
    21361 caaacgttgt ctgtcatgaa agatagtcct tattttgccc gtatcgactt taaagaagac
    21421 cgtgaaacag aaacattata tctaggtatc gcttctttaa gagatctggc agaagaaaca
    21481 atcgttattg actggcgcgc accaattgcc aatctttatt atgaaggtga gattggtccc
    21541 gcattttatg aaactgaaac agatagaata gatgtcgatc tgcagttgaa acgacaattt
    21601 aaaatccaag aaggacgtat tttatctatg gtagatacgt cggaagtaat caatgatgac
    21661 tttttgctag agatattgga tgaatcatca agcaaccata tgaaaaacat cgtctctacg
    21721 atacaaaaag cacaaaatgc aatcattcgg gacacaacaa gtaaagtaat gctgattgaa
    21781 ggaatcgccg gaagtggaaa gacatccgct ttgcttcaac gtattgcttt tctgttgtat
    21841 cataatcgca agtggctcga ggctgaaaac gttcttctat tttcacccaa ccatttgttt
    21901 tctgattaca tctcgactgt attgccttca ttaggtgaaa gcggcgtgcc tacacagaca
    21961 ttcaaaaatt atttggtgca gctgctgcca gagttttctt tactagatga acagcaacaa
    22021 gaaagtggtt ttttgctagg ggaaaaagat ccgatacaag tgatgaaaag cggattgacc
    22081 ttagtcgatc agattgatcg ctatatccaa ggcatcacaa actacggtcc cttgttccgt
    22141 gatatgaaaa taaatggccg tacgatccta tcaaaggaat cgattcgcca atggtataaa
    22201 gaaacaaatg aacaattacc tttacatcat agactttctc tattacaaac gaagctcctg
    22261 aaaaaattag gcggtctgca aaaagacgaa acacgtcagc aatgggtcaa agatctggcg
    22321 gaagaacagc tccaagaact atacgcaaca gatccaaatc ttgaatatac agaacaaaag
    22381 gagcgttcat tacgtaaaaa actggccaac caaatcgtac gtaaaagatt ccgtcgaatc
    22441 catcgaggga tcatgaatta tcaatttgtc aatataacga aacaatatct ccactttcta
    22501 caaactgtgc cactttctct tctaacacga cataaaatca gcgagaccag gtggcaggaa
    22561 catttgacaa ctgttcgtac acacttgcgt caaagagaat tgcgtcaaga ggatgctgta
    22621 ctattctttt tactgatgcg ccgaacatat ccagtgacgg ttacacacaa agctcgctat
    22681 atctttattg atgaaatgca ggatttcgca ccatcacaag tggcattgct gcaagccttg
    22741 ttcccaaaag caaatttgac tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa
    22801 acgatcgttg gatcattgga agaccttttc gtggaccgtg aagtcactcg tttccaatta
    22861 acgacaagct atcgctccac aaaagaaatc actgattttg ctaatcattt tattgtgaaa
    22921 gaacatcaag tagaaacaac agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca
    22981 acagatgata tcaaattgaa ttggttagca gataccattc gaacgactca gggaaaagcc
    23041 cggtattggc gtacagcaat catagctaaa acacaagaag aatgcgaagc tctttatgct
    23101 caactgccag acgagttgaa acaacaagtc cagctgattt taaatgagag tgactttatg
    23161 aagcgttcca ttattttact tccagccttt ttagcaaaag gtctggagtt tgaccgagtt
    23221 ttcttgtggg atgtagatgc agaacatttt tcttctcagc aagacaaatt gatcctttac
    23281 accatgtgta cacgtgcgat gcatgaattg acccttttta cctccaataa tgaaagtcct
    23341 ttgttaaaca atatggatat ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa
    23401 ctgctatcat taatgttagc agttgtcttt ttatttacaa taataattgc agaaaaagta
    23461 attcaatcat ttaaggtcat ttattctata tataaatcca aatctgtttc aggatatttt
    23521 aatttgacaa gcgaaataat cattttcagt tcttccatgt tttctggata ttctgggtca
    23581 aataccttgc tatgacggcc aatcccgcca ttgtcgatca atcggtaaat tcgattccat
    23641 tcaatgaatt ggtcaattga ttggaaattg ctgattggat agccgccaca atccaaaatc
    23701 tctgatacac gaaatgctag gtatgcacta tcgatcactt tatttttttt cgtgtctatc
    23761 ttctcatttc tttcgataag aattttttca ggacgatgtt tcaagctcca ctctaatagt
    23821 agaaagaaag cctccatccg atactcttct tcaaataacc gaaaggctga atcagaacga
    23881 cgaaaaagca gcggaatcag ataattttgt ctataaatca gcattggtgc gcggtccacc
    23941 atacactcta aataacggtt cagataccct gtaccgacat agtttcctaa tcgatagcct
    24001 tcaacgccga atcttgcgta tttttgcgct aattttgaac aatcagttac gttcacagct
    24061 aactcttcta ctttgcggta accgcttaag atacgttcaa aaggttctaa agtgattttt
    24121 gcttccatat tcttccccgt ccatcttcca catacttcat atcatttcac atgatactta
    24181 tgctctcatc ataccacagg ttgaattaga aaagaaaata aatcacacaa aaaagcaaga
    24241 caatctgtta gtgagattgt cttgcttttc gaaaaagact gaatactttt cgttaaaact
    24301 ggttgcttag tcttctaatg ccacattatg gaacacatgc tgtacatctt ctagatcttc
    24361 cagtgcatca atcatttttt caaatgtttc ttgatcttct ggagatagtg ttacctcgtt
    24421 ttgagggatc atttggatct cagcgattga aaaatcagtg attccttttt cttttaatgc
    24481 ttcttgtata ctatggaaat ccgctacttc accgtaaacg atgatttgtc cttcttcttc
    24541 cattacatcg cgaacatcga tgtctttttc cattaggtat tcaaggatct cgtcagcgtc
    24601 ttctcctgca aaagcaaaga ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac
    24661 acccatgttc ccgccatttt tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac
    24721 attgttcgtc aatgtatcaa caatcaccat tgagccgctt ggtccaaatc cttcatagcg
    24781 caattcagag tatgtttcat ctcctgcacc ttttgctttt tcgattgctc ggtcaataat
    24841 atgttttggt acattataag ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc
    24901 atgcggatca ggatcacctg attttgctgc cgcgtagatt tcaatcccaa attttgcata
    24961 aatccggcta ttattagcat ctttagcagt tttctttgct acgatatttg cccatttacg
    25021 tcccatattt tcacttcgct ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc
    25081 cattatactt gtgaatcacg attctgtgaa gctttttttc tttcttcctt cattcttctc
    25141 atttttagtc aattatctat actcggattg ggatttgccc gaaattctgt tccggaatat
    25201 tgcctcccaa ttgatagatt tgatcacttc taactaacag ttccgcttct tgtgcctctt
    25261 tttttccgat tcgggaataa atagaaatct cttttttttc ttttaagaat cttcttccag
    25321 catcggtaaa tccaagtagt cgaagataat ttttattttg ttggacagga atctcttgct
    25381 ttttgatatt cagcaagaca taacaagata atcgttggat ccgtgtccat gtatatcttt
    25441 ttgtttttac ctttgacaca aaatcctcaa aactatcagc agttgcagct gctgttttca
    25501 tgcgcgattc tattccttcg gtcatctgat agatatctgt cagttccagc aaagtagaag
    25561 ataacaaccg ataacgcaaa tacggccaat aagattccca agtctgcagc gaacaagttg
    25621 aaagatcttc ttctgtctga ggcggcacaa gtccagctat tctttttcct tcttctaacg
    25681 catggcgaat ggctgttgca ctggctatcc tctgatctgt gatgattttt tcatgatagc
    25741 ctgcactttt acgtcggatc ggatgtaatt ccatagggtg gacatacttg gcattttcct
    25801 ttgcataact taatcccaag atatgatttg gcgaagaaaa atcaagcgta atatcgggat
    25861 acagactgcg aaaaacctca gtcatttttt gcggataact atacgtttga tcagacagtt
    25921 cttgaaatgc ctcttctatc ctatcttgat tctcttggac aaagcgtccg aaactgctgt
    25981 aatcaaacga agtctcttct tctgttccaa aacacaaact gtcacagtcc agtgtttgca
    26041 agatttttac tgcaccttta gcaaaatagt cagctgactg aaccgcccat tcgacgggaa
    26101 gctccactac taaatccaca ccattttgta aagcttcatt cgcgcgatgc catttatcga
    26161 tgatagccgg ttcgcctctt tgcaaaaaat tcccgctcat tacagcaatg acgacctctg
    26221 ctcctgttat ttttcgtgcc atttccacat gatagcgatg tccattgtga aaaggattgt
    26281 actctacgat aatcccgcag cttttcatgc gcatcctcct tcatagttat cgataaaaaa
    26341 gaaatagaga caagtaaaaa aaggcaaaaa tcggaaaaaa tacccgaact atataaacta
    26401 ttctcgcaaa cacaatactt ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc
    26461 gttcggatat ataatttatg ttgaagattt attcttttct tgttaactcg agcaggcaaa
    26521 accgctagtc tttgtatgct acaaagaacc agcgctttga tttctctgat gctgcttcgt
    26581 ctgtaaaatc agaaaatgct tcgactttcg aaaagccgct gttttccagc attcttaaat
    26641 aactttccaa tggataggta cgctcttgat gtagttcatc ttcacgaata aatcgaccag
    26701 acccttcttg ttcttcaacg aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc
    26761 ctggataact atcccacaaa aaagcaaaat tatccccttg ataatgatag ctatattctg
    26821 gaaaaacctc atctacttga taggtggagt gtacgtcaaa taaaaatcgg ccattttctt
    26881 ctaacgcttg atagacttca tcaaacactt gctgtacctc ttgtctattt ttcatatagc
    26941 acagcgaatc agaaaaacag gtaattgcct gatattgtcc gatttctgat aaatcgagca
    27001 tattgccttc cacaaattgg atcgatgcgt cttcttcata tgctcgctgg ctggcaatca
    27061 tcaacatctc ttctgaaagg tctaaccctg tcactttata tccatctttt gcaaaggcaa
    27121 ccgctaatgc tccagtaccg catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat
    27181 gacgtttcga aaaagctaac cattgctgat aaagtgtttc gtccatcact tcatcgtaaa
    27241 tgaaagcaaa tgtttcataa gccatatgtt aatccaacca ttcactaaga tcgactagcg
    27301 gagcatctga ccatagtttt tccagattat agaaatttcg ttctggcgca tggaaaacat
    27361 gtacgatcac atctccaaga tcgatcaata cccattttcc gccttctttt ccttcaatac
    27421 gttttacttc atatttgttt tcttcttctt tatcaatgat ttcttctgta attgcgttga
    27481 tttgacgttc gctatttgct gaacagatca tgaaataatc tgccaacaag gaaacatttc
    27541 gaacgtctaa agcgataatg tcttctgccc gttttgaatc tgctgcttca atcgcaattt
    27601 ttaattgttc tttactatct atgatgattt cctcctaata tgagcagctt atttttttgc
    27661 tacccagtaa ttatatgttt cgattgtttt tggataaatc tgttgttctt gcgcaagcaa
    27721 atgggccaat gtatgttttg tttcaaatgc tacagcttcg tctagatcag cccatgcaat
    27781 ggctcgtgca tcttgtaccc caggaaaatc tcgacctggt tcaatatagt ctgctacata
    27841 aatgattttg tcaaggagac tcatcttagc agccccagtc gtatgcaccc ggattgcatg
    27901 aagaatctct gcatcggtga ttcctaattc ccgctctaca aacgaagcgc caacaagacc
    27961 atgccagatt gcattattat aattcaataa ctccggatca aaaccgtctc ttacgattac
    28021 cattttgaac tcctcatctg gtcgttcttt tgcataatca tgtgtcaatg cagcaatact
    28081 agctttttca ggagaagcac cgtatttttt ggcaagagcc acggctgttt cttctactcc
    28141 aagcacatgc ttgaagcgtt gttcgctcat tctcatctgt attttttgca tcaggttttc
    28201 tctagaataa gcagtatatt cattactata gtccatattc atacaaccct tcattttgaa
    28261 tataatcaat tactttatct ggaacaaggt agcggataga acagccttct ttgatctttt
    28321 gacgtatttt cgtggaactg atgtcgatct caggtacatc tacccaaatt acaggatatg
    28381 gagtatccgt tgtgtatcct ggtcgacgta tacccacaaa gttgaccata gaagtcagct
    28441 catcgatttt ataccatttt ggcaaatatt ctaccatatc cccaccgata ataaagtaat
    28501 aatctgtatc cggattgttt tgcgtcaatt ccttcatagt atcataggtg taacttttcc
    28561 caccacgagc taattcaatc gtttcaatct gcaaaaaagg attgtcttcc accgctaatt
    28621 ccaacatgtt gagtcgatgt tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct
    28681 gataagaagg catcaaaaat acgcggtcaa gacctaaatt ccggccagct tgttcagcca
    28741 tcactaaatg tgcaaggtga acgggattga atgttccgcc caagatccct acttgctttt
    28801 tcttctctaa gaattgaggc atttcttcag gaaataattg tgaacgaaca aatgtcttag
    28861 cttgcgtatt catcatggtc actccttata ttgcttttac ttcttttgat agcctttgat
    28921 acttttcttt tgtggaaggt ttgtataata caataacacg tccaatgatt tggacgattt
    28981 cgcaatctat ttctttttct aatacttgag ctgcttcttc tgcaatctca tctgtatttt
    29041 gaagtaacga tactttgatc agttctcttt tttctaaagc ttcttcaatt tgaacgatca
    29101 ttgctgaatt gatcccacct tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc
    29161 tacgtaaaaa acgcttttgt tttcctctta aactcataat tttccttctt ccttaaatca
    29221 atgctttgcg tttcaataca tctacaccct ttggcgccca gcccgcaatt actactggcg
    29281 ctgttacagt gatccagcct agaccggcaa aaacgatgtc tgttttttct ttcacagaaa
    29341 actcaaaacg aacaagctcc ggaaatgcct cgacttcatc aggacgagga ggctgtaata
    29401 atccacctac atgtttttga taaaattcgt ctgctttttc cagtttcgtt cgatgaatat
    29461 ttacatcatt tgacacataa gcaataaatg aagcacgatt gccgctgata aaatcaaatc
    29521 ttgcaagtcc gcccaagaaa agtgtttgcc cttcattcag ctgataaact ttaggtttga
    29581 tttcttttaa cggtgcaatg atccgcaaat cttttttacc taagtagtgc gccatttgat
    29641 ggcgatggat aattcccggt gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga
    29701 ttttatccaa ggtcgttcct ggaaactgcg aagttgtgat tacatcttgt actcccgctg
    29761 tatttttgat gatttgattg ataagcgtcg attttccgac atttgttact ccgacgatat
    29821 agacatcccg tccatcgcgg tattcttcga ttttttctaa tagttccgtc atctcatgag
    29881 atttcttagc actagttaat aatacatcta ctggacgaat tcctgcttcg taagcacgtt
    29941 ccttcatcca ttgtgttaat ttagtttttt tcaatgattt aggtaatata tccactttgt
    30001 tcccaactaa aagtactgga ttgtcaccga caaaacggtg tagtcctggg attagtgaac
    30061 cattgaagtc aaaaatatcc accacattga cgatcaatgc atctttttgc cctaattcat
    30121 tcagtaagcg caaaaagtcg tcatccgtca atgagacatc ttgggtctca ttataatggc
    30181 gtaatctgaa acaacgctga caatagactt ccccggaagc taaacctttt tccaaagccg
    30241 tttgcggcgt gtatcctaat tcaccgggtt tgtttgtttg tataacggca ccacagccga
    30301 tacattgtaa ttcttctgtc attcgattcc acctcgccag cccatatcag ggtgttttgc
    30361 taatagatag gccataattc ttttttccca aaaacgatta aattgtgtct tccaactatc
    30421 tgttgcgata atgggtttta caaggatgct acgtatccct gcacgattgg ctccacgtat
    30481 atcagtcata atctgatcgc ctaccattac tatctcatca tctgctaaat ccaattgttt
    30541 ctttgctatg ttgatccctc ttgctaaagg tttcattgct cgtgcaacat acaaaagatc
    30601 aaatttttca atcgctcgcg cgacacgttt tgaattattg tttgaaacaa caacaacagg
    30661 gattcctgca tttttcattt ctaaaatcca agtaagcaac tcttctgttc catctggatt
    30721 attccatgca atcaacgtat tgtctaaatc ggtcaatact gctttgatgc ctagattctt
    30781 taattgggca ggtgtaatct gatagatggc ttctaccatc catgttggtt tgtaatttga
    30841 aaacatgctg tctcctcatc tgcaaaaaat gaaggagcac ataaagtact cctcaacccc
    30901 gtattatact gcatatcagc aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa
    30961 gcatttcttt acaaaatgac caaaaataaa gattgatcac agaaaaattt agaaacaaaa
    31021 aacaactaat attggcggaa cctcttgtat cgtttttcca gtaatttatg ctgatctaat
    31081 cgaacaagtt ccgtcaatct ttcaatcaac gcttttttca taatgtgtgc gactttatat
    31141 cgtggcaact gctcgccgtt gaacgtttca ggaataactc gatcaacgat tcctaactcg
    31201 cgtagttctg gcgcagtaat tttcatcaac tcagctgctt ctgcggcgcg actaccgtct
    31261 ttccacaaaa tcgacgcaaa tccttctgga gaaagcacag cataaatcgt ttcttccagc
    31321 atccagactt catccgctaa acctagagca agggcaccgc cacttccacc ttcaccaatg
    31381 atgatggcga tgatcggtac ctttaaatca gacatttcga gcagatttct ggcaatagcc
    31441 tctccttcgc cgcgctcttc tgctcctaca ccgcaatatg cacctgctgt attgatcaag
    31501 gtaatcaccg gtctattgaa cttttccgct tgtttcatca gtcgtaaagc ttttcgatag
    31561 ccttcaggat ggggagaacc aaaatttctg cggatatttt cctgcagatc ccgtcctttt
    31621 tgaataccga tcactgttac cggtttgcca tctaatcgag cgattccacc aacaatcgct
    31681 tcgtcatctg caaataaacg atcaccatgg cattcctcga aagaatcgaa gatctcttca
    31741 aaaaaatcca agcttgtcca tcgttcttta gctcttgcta actgaacgac atcatgtgct
    31801 gtcttatcca cgatctatcc atcctttctg tgtatgcaat tcaagaagcg tatggatttt
    31861 ctgtttcaat tccatgcggg gaacaatctg atcgacaaaa ccatgagata ataagaattc
    31921 agccttttgg aaatcttctg gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc
    31981 agcaaaaccg atcaagcttt ggggttctgc tagaataata tcgccttcca ttgcaaaact
    32041 ggcagttact cctccggtcg tcgggtccgt taaaacagtt agataaaaaa gaccttcatt
    32101 gctatgccgt ttgacagcag cagagatttt tgccatctgc attagagaaa agattccttc
    32161 ttgcatccgt gcgccacctg aagctgtgaa caagacgact ggaagacttt cctttgttgc
    32221 tcgttcgaat aatctggtga tcttttctcc gacaatcgtt cccatacttc ccatgataaa
    32281 attaggatcc atcactccaa taatgaaggg aatcccctga atggttgctt taccagtgag
    32341 gactgcttca tgaagtcctg ttttatcttg cattttttta attttttccg tatattcggg
    32401 aaatgctagc ggatctttgg ttacaagatc cgtatcccat tcttcaaaac ttttttcatc
    32461 aataatcaaa gctagacgct gccatgcacc gattcgaaaa gcgtatccgc aatgagggca
    32521 tactttttct tcaccgatgt ctttcgtata aaggatatgt ttgcaatttg gacactttgc
    32581 ccacatgtta tcaggaacag atggcgagtt agcaggtttg ctctctctat taggattgat
    32641 ccgaatatat ttctttttct taaacagagc catctatgcg cctcctatct ccgtttctgg
    32701 tgtccaattc ggtaaaaatt cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac
    32761 tgcaggatga ctaatcaaat ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat
    32821 aaattcactt aaggctcgct gcatcttcat taatgcttca aaacgcgtat ttccatggac
    32881 gattattttt gcaatcattg aatcataata tggcgggatc gtatatcccg ggtaaactgc
    32941 actgtctact cgcagtccca tcccacctgc tggaagcagt aagttttgga tcttccctgg
    33001 agaaggagca aaatggaaag caggattttc tgcattaatc cggcattcga ttgcgtgtcc
    33061 ttggaatact acttcttctt gacacacatt caaaggctca ccggctgcta tctccacctg
    33121 tttttttact aaatcgattc ctgtgaccat ttctgttact ggatgttcca cttggattcg
    33181 agtattcatt tccatgaaat aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc
    33241 ggcattttca taattgactg ctttagctgc tcgaacagca gcgtctccta gtgcttctct
    33301 ttttgtttgt gagatcacta cagaaggaga ttcttccagt actttttgat tgttgcgttg
    33361 taaagaacaa tctcgctcgc ctaaatgaat gacatgacca aatcgatcac ctaagatctg
    33421 aacttctata tggcgagcag gataaatgat tttttccaaa tacatatcat catttccaaa
    33481 tgccgctgct gcttcttgct gagctgaaga aaaatgctgt gggagctctt cttttgattg
    33541 aactttccga atgcctttcc cgccaccacc tgcagctgct ttcagcatca ctggataacc
    33601 aattctgtct gctatttcca atgcttcttc tactgtagat aatacaccag tacttcctgg
    33661 aatgactggg acatttgctt cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc
    33721 atcgatcgtt gcacttttag gaccaataaa tgtgatattg cactcttcac acatggaggc
    33781 aaatcggcta ttttcagata aaaaaccaaa tcctggatga attgcttcgg cttttgtcac
    33841 gattgcagcg ctcagtactt cctgaacatt cagatatgaa tcaacggctt ttgccgggcc
    33901 aatgcagatt gcttcatctg ctaactgtgt atgaagtgct tcggcatctg cttctgaata
    33961 tatcgctacg gtttggatcc ctagttcgcg gcatgcacga atgatacgta cagcgatttc
    34021 accgcggtta gctatcaata ctttagaaaa catatttcac ctatccaatc ataaaggtta
    34081 attccgcttc ggctactttt ttaccgtcta ctttagcgat tcctttgcct attccggctg
    34141 aagctttcac tttcaatatc tcaacttcaa ggtataaggt atctcccggt gtaactttct
    34201 tacggaattt tgctttgtcc aatccgccga aataagccgt ctttcccttg aattgttcaa
    34261 gagaaagtaa tgcaactgct cctgcttgag ccattgcttc aacaatcaat acccctggca
    34321 taacaggttc ttctggaaaa tgtccttgaa aaaagggctc attgatcgtt acatttttct
    34381 tagcaacgat ccgttctcct tcaaccattt cttccactcg atcaatcaaa agcattggat
    34441 aacgatgtgg aatgatttct tttatttctt gtatgttcat tgttttccct ctttcctgct
    34501 ttgcttattt ttgctgaatc ctaaagagtg gctgtccata ttcgacaact gactcgtttt
    34561 ctacaaggat ttctgtgatc actccgtcgg cctcactagt tatctcattc atcagtttca
    34621 tcgcttcaat aatgcagata acttctcctt tggcaacttg atcacctact tttttgaaag
    34681 ctggtttgtc gggcgctggt tgcagataaa cgattcccac gattggcgaa acaacctcga
    34741 ttccatcaaa tactgccgat tctttttctt tcattatttc tggagcagtt gttgcttgtt
    34801 caggtatgac attgactggc tccgaaactg gcaacgtttc gtttgtttga accatattca
    34861 tgcctcgact tgttttattt ttattcatat acaattcaaa ttgaccttca cgcaaatcga
    34921 attccgttag cgaggattga tcaaattgac tgactaattc tctgatttca ttgatatcca
    34981 aaattattcc tcccagcgtt tcatgcacag aaccgcatta tgtccgccaa accctaatga
    35041 attactcatt gcataagtaa aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc
    35101 aatctcagga tcttgttttt ctacattgat cgtaggtggg ataaattgat gttctaatgc
    35161 cagcaaagtt gccaaggctt cgatcccgcc ggctgctccc aataaatgtc cagtcatcga
    35221 tttcgtgctg ctgacgtaag tatctctgaa attttcacct aatgcgattt ggattgcttt
    35281 tgcttctgcc tggtcattgg ctggtgtact tgttccgtga gcattgatat atccgacttg
    35341 ttccggctgt acaccagctt cttccatcgc aagcttcatt gctttagatg caccagaacc
    35401 atctggagta ggagctgtca tatggtaagc gtcacagttt gcaccgtatc caacgatttc
    35461 tccatagatt ttggcaccgc gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc
    35521 tgctccttca cccatcacaa aaccattccg attttcgtca aacggaatcg aaccacgatt
    35581 aggatcagtt gattctgaga gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca
    35641 aatcgttgct tctgttcctc cagcaagaat gacatcagaa tagccatgtt tgatgttacg
    35701 gaatgcttcc ccaattgaat tcgttccgct agcacaagct gttacgatag ctgtacaaat
    35761 accttttgca cctacacgca aagcaatatt tccagctgcc atgttggcaa tcgccattgg
    35821 tacgaacatt ggagaaactc gttttgcacc tttttcatgt agacgaataa cttggttttc
    35881 gattgttgga agaccaccga tcccagatcc gatgatgacg ccaaaccggt cttgattcat
    35941 tttttcttta tctaaaccgc tcatctccat tgcttctaaa gcagcgtaga ttccatagat
    36001 cgaaaacata tccattcgtt tgctatcttt tttaataaaa tatttatcgt aagggaaatc
    36061 tttgacttca cccgctaagg taatccctgt ttctgaagca tcaaatttag tgatcggtgc
    36121 gatgccattc gtcccctctt ttaagctatt caaaaagctg tctgcgtcat ttccaatagg
    36181 tgaagtgact ccatagccag taattaccac tcgattcatt tgtttgctct ccttttctta
    36241 tccgtgcatg accaatccgc catcgacatt gatgacttgt ccggtgatat atggattttg
    36301 tgctaagaaa actgctgttt gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat
    36361 ttgcttttcc gcttgttcct tgactttgtc tgctaaaact tccgtcatat cagttgtgat
    36421 gaatcctggc gcaatggcat tacatgtaat gcctctagtt gcagcttctc gtgccacaga
    36481 ttttgttaat cctactacgc cagctttact agctgcataa tttgcttgac caatatttcc
    36541 aatcaaccca gatacactag agagattaat gatggcccct tctcgctgct tcatcatttt
    36601 tttcaatacg tgctgcgtca tattgaaggt tccaatcaaa ttgatatcca gacatttttt
    36661 gaaatcttct gcatccattc gcatcacaag tttgtcattt gtgattccgg cattgtttac
    36721 taacacatgg atcgatccaa gcttttcttc tgcttctttg atcatttgtc ccgctttctc
    36781 ataatcagag atgtcaccgg aaactcctac gcattttaca ccgaatgctt cgatttcttc
    36841 tatcttttct tttggaatct ctccgcgacc attcaaaatg atatttgctc cagcttttgc
    36901 aaaagctaag gccatcgctt tgccgattcc tcttgtacta cctgtgataa atacattttt
    36961 tccttttaca tccataacgt tcctccttat agtattgcta ttgtttcatc aaatgtctgc
    37021 ttattctcaa cacgcagaac tggtattgtt ttatcgattt ttttcataaa tccgcttaat
    37081 acttttccgg ggccgacttc gatgacttgt tcgatgccga ttgtttttaa cttatggata
    37141 ctctcataga aacgaacagg ttgcatgact tgctgttcaa gtagtcccgc gattgtttct
    37201 ttcttcatta tttccgttgt tgtgttgctt atgataggaa aagaaggttc agagaattga
    37261 atctgactta ggtccttcgc cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa
    37321 ggcccgctga catttagagg gatcattctt ttgaaccctt tttcttttaa tagtaaaaca
    37381 gcttcgtcta ctgctttttc ttcgccacca atcacgatct gctgaggtgt attataattt
    37441 gcaggagata cgatgccgta cttgctagct tcatgacagc tttcctcgat cgtttcaatc
    37501 ggcgcattca tcactgcaac cattttcccg cttccagctg gggcagcttc tgtcatataa
    37561 gcgcctcttt ttgctactaa cgcaactgct tcagtgaagg atagcgcatt actagctact
    37621 aatgccgaat attctcctaa actcagtcct aaagctgcat ctgggatgat tccatgctcc
    37681 ttcaataagc gataatacgc gatgctgact gttagaatag ctggctgtgt atattgcgtc
    37741 tgatccaaac gttcattttc tgtaaagcaa agttcagcca tatcgtagcc gagaatctca
    37801 cttgcttcat caaatgtctg ctttacaacg gcttcttcat ataaatcttt tcccatacct
    37861 tgatattgtg caccttggcc actaaataag aatgctgttt tcatgttttt ctccaatata
    37921 tccagaatat atgtttgatt cttcctattc aaaaaggccg agacattcct atttcaggaa
    37981 atgtcccagc ccccaaccta attttaatga ttatgcagtt tgtttttcta cgtaagtcac
    38041 taaatcttga accgttttga ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc
    38101 aatttcattg atgatttgga ataaatccaa gctgtcagct tctaagtctt cttggatgtc
    38161 agtagtcaat ttgatttctt cagtttcttt tcctaattct tctgcgatga tttcttgaat
    38221 tttttcgaat accataataa tatattcctc cgatattgtt tgctttttat ttttataatt
    38281 taacagtcta caactccatg agaatacttc cccatgttaa acctccgcca tagcctgtaa
    38341 atattacttt ctgctgtttt cctaaggtga tctttccact agaaactgct tcatccaata
    38401 agatagggat gcttgcagca gatgtattcc catatttatc catattggtc aggaactttt
    38461 cttgcggcat ctttactttt cgggcaattt tctcaataat tctgaggttt gcctgatgca
    38521 aaagcagata atcaactggt ttgtctttca tgacttcttg gatattgttt gcaacgtctc
    38581 gtacggcaaa atcaaaaata tctctgccag tcatttgcaa ataatacgaa ccttctgaat
    38641 cttctgaata gaacggattt ttattttgct ggtagccagc ggtcaatgag ctacttctgg
    38701 taccgtcagc tgctaatttt tctttcagca attttttctg tggattcgct tctaagagaa
    38761 tcccacctgc tccatcgcca aacaacacag cagtcgtacg atcagaccaa tcgattagct
    38821 tagatagtgt ttcaccacca atcaccagtc ccttagttga gccgcagcgg atcatttttt
    38881 cagccatgct taacgcataa acaaatcctg agcacgcagc actgatatca aaagcgatag
    38941 catgagttgc tcccaatttc ccttgtactt gtgctgctac agatggtgtc gtgtaatcgg
    39001 gcgacattgt tgctactaaa ataaaatcca aatctttagg gtttagattt ttctgtttta
    39061 tcaatttttc cgccactaaa atgcataaat cagaagtctc ctgatttgtt acacatcttc
    39121 gttcacgaat acccgtcctt gacgaaatcc attcatcaga ggtatccatc atcttggaaa
    39181 gatcattatt agtaataatc ttttcaggaa ggacgctggc tgttgcagta atcattccaa
    39241 attgttccat taaatatcct cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg
    39301 catccagcaa ggcatgctgt tcctccgtag ccattccgtc taagatgttc ttgaccattt
    39361 cacgatgaaa atgctgatgg acccgaaata gtaactttcc ttttttcgtt agtcccaact
    39421 ttacaacgcg gcggtcatct tcactgcgga tacgttcgac atagcctttt tttactaact
    39481 tgttaatagc agtggtcaag gtcccaacag taattgatag ttctttggct acttctgaag
    39541 ttgttttttt cttgtacatc ccgattgcct cgatcgtgtg catctctgtg attgacagat
    39601 ctttgaattg agattttttc agctcagact cttcgattgt caaaatatca ttgaagacac
    39661 taacaagata atcatttact gtttttaaat ctggttccat gttccaccgt ccactaatta
    39721 gtttgattat caaatctttt gatgttcaaa ctatatctta acttttttca aaatgcaacc
    39781 ttaaaagatc atttttttac tatatgagct ttttttaaga ttttactcat ttaaaacaac
    39841 tgataaatca gcatttataa tttcttttat tagaaaaatc atctatctca catattttga
    39901 ttatcaaagt attttctgtg aacagaacta tagaattccc taaaacttgt ccattatttc
    39961 aaaatttgtt atagtctttt tattcaaagc gtaaaaggag atcctatgtt aaaagaaaaa
    40021 atgaaaactc tccccatgct gccgggtgtc tatcttatga aagaccgaga tggtaaggtc
    40081 atctatgttg gtaaagcaaa acggctcaaa aatagagtaa gcagctattt tcatcagaat
    40141 aaacagcatt caaaaaaagt attacgtatg attcatcata taacagattt tgatttcgtc
    40201 gtagtagaca cggaattaga tgctttattg ctcgagtgtc aattgatcca acattaccgt
    40261 cctttttata accgacaaat gaattatttc agtaattata attatgtaca tattaccaat
    40321 aagggatttg tattaacaga tactcctacg gctcgaacat acgggccttt tcgtctctat
    40381 aaaaaaatgc cgtctatttt gcgtataatg gaagaaactt atcaaatgcc ttggttgtct
    40441 gaaattagtt tgttagcttt gcgagtccag cttcctgacc tacaggaaat gacttttgaa
    40501 cagaaaaaaa aggaactcca agggctgttt caaggccgaa ataaaaagct actgacttac
    40561 ttgaaaaaaa gacaacaaca tttcatctat cagttgaatt tcgaaaaagc cggtatgctt
    40621 caaaaagata tcgaattagt tacttatttt attagacgga tccaggaaca aaagcagttt
    40681 ttaagaacac catcgctcac cttcagcatg ccattagcag cagatgagag tcagaaaaag
    40741 cactacctcg tttgttatgg tcaacttgca gaaacaatga ttacctctgg tgacgtttct
    40801 cctgacttct attatgaaaa gaaagaagct catttatctt tgaaacgtca attgtcaaaa
    40861 gaagaaatcg atcctgtaca aatcttgatc agttaccgca aaaaattaga aaaagaacag
    40921 tttgaaattg aactgttaaa caaaaaagaa gctgaaaagc aactaaatta gttgcttctc
    40981 ggcttctttt aggcatcttc aacttcaaat gtcaattatc ctaaaattta ttggattaag
    41041 tcatagattt ccatcgctac gatatcgata ttatcaaatt cgtattgctg atgagtatct
    41101 gtttcagtta attcaaatgt atcggtcgct ttatcataag ttactgtaca cttctctacg
    41161 ccttcttttt caaaacggcg aacttgcagt tcattatctg ctgactcgac catagcctcc
    41221 agtcgtttta tgattgcgac taattgtgaa tgtgtcatcg gaggtcctcc ttttcttatt
    41281 tctgttatat tgtatcaaaa gcatagccta cttgcattga ttttctctaa aaaaactcgt
    41341 tttttatgat tttttttctg gtatttttcc ttcaggccac caaagtttga tcaaagcttg
    41401 ggttccgtca ttctcaaaac ctttatctgc caactcttca tatagtttca atgcttgggt
    41461 agttgctggc aatacaagat ccattttttc tgcttcttct aatgcaatct ttaaatcttt
    41521 gataaaatgt ttgacaaaaa aaccaggtgt gtaatcttct tttaaaatac gaggagaata
    41581 attgcttaaa gaccagttag ctgcacttcc acctgaaagc gtctcaatca ctttctttaa
    41641 atcaagtccg tttttttgtg catagacaag catttccgtc attcctgtca tcgtacctgc
    41701 aatcatgatc tgattagcca tttttgtatg ctgacctttc ccagcagaac catgcaatgt
    41761 aaatgtcgta ccaaattctt tgaataaagg cagtacttga tcataaacgg cttcttctcc
    41821 accgaccatg atcgtcagtg taccattctt tgctcctaag tcaccaccgg ataccggtgc
    41881 atctaacgca tctgcgcctt tttcttttgc tgtttttgca attttttctg ccaggcttgg
    41941 tgtacttgta gtcaaatcaa ctaaaatatg tcctgagata tctgcagaaa aaatccccga
    42001 ctgtccatag tagatttctt ctacatcttt ggggtaacct accattgtaa agagaatatt
    42061 actttgttct gctaccgctt ttggtgtatc tgcccagata gctccttctg ttactaaagg
    42121 atcagctttt gcttttgtcc gattatagac agctacttcg tgtcctgctt ctagtagatg
    42181 gcgtgcgaca gcacttccca tgacgcctgt tccgataaaa ccaagtttca ttttttcgac
    42241 ctcctaaaaa tcaaaaatcc ttgcttctat gctagtatac gctagaaaca aggatttttt
    42301 cataaaaaat gtttgaattt tatcttttaa atgaatttaa ttttattttg attcgttcaa
    42361 tcgagtcttc ttcttctttt cttcgcatct cttcttcatg ataaacaacc atgtcttgat
    42421 aaaattcgat catagcttcg ccgaaatgtg tagatgaaat atcataaagt ttagcttcta
    42481 aaacttttgg atctttagga acttcactgg aaatataatc aataagtgct ggtgcaaagt
    42541 cttcgtcggt ttcaaaagtt ttccctaatg aaggatgatc gaacaatcgg ttcaaataag
    42601 catttccttc cacgacacaa ggtgttccgg ctgccatcgc ttctgtataa gtaagccctt
    42661 gtgtttctga agtagaagca ctgacaaaat aatctgccgc tttataataa agtgctacat
    42721 cattgttgtc cacttctcct gtgaactgca caaattcttc taactgcagt tctgagatca
    42781 attcctctaa ctcttctaca taaggtcctt ttcctacgat aactaatctg gcgttaggat
    42841 aagcggagat gacctgagga aacccattaa tcaaggcttg gatatttttc tcataagaaa
    42901 tcctgcttaa agaaagaatc atcaaatggt tttcctgaag acctagtgac tcccttaatt
    42961 tgctgatatc ctgctgagtg atatcagaac gtttgaattt ttcaatgtcg ataccagtag
    43021 gaatcacgcg aagcggtgct attacaccat agctgcgtaa tgtatcaata acacgttcac
    43081 ttggacaaac tacacctgtc gtatgatttg caaataatct agacaagtat tttacatggg
    43141 attgcctgat cacttttcct ttaccgatat aatgaaggta gtcttcatac atcgtatggt
    43201 aagtatggat cagaggtatt ttcaacttct tagctaccat cttcccaagt atccctgctc
    43261 cgaattctgt atgggtatga ataagatcta gttctagttc tttggcaacc aaataagcat
    43321 accacatgcc tctaacaaca actcttcgat ccttgaaaga aataaatggt acacttggca
    43381 ttcgaatcac atctttttcc aacttatccg cattaggatc ggtcgttgta aaaatataga
    43441 cttcatgccc atgtctttct aattcttgtt ttaatgtttt gatcgatgta gcaactccgc
    43501 tgacttgcgg aaagtaggta tcggtaaaaa agccgatttt catgtttttc gcctccaaac
    43561 tagtccttga cctgatttac tttttttaat ttgctagaga ctttttcatt cagtacactt
    43621 tcgtatacat ttttaagttc ttcaccgatt ttattgatac ttcgctcttt tgctgtttga
    43681 taaccggctt gtgtcgtact cggtagttct tgattggtaa tctgttggat cagtcggata
    43741 aattcttcgt ttgtcttccc catatagcag ttcttgctat cttctaacca gccattatac
    43801 actggaatat ctcgaacaag tacgttttgt ttgcttgcta aagcttctaa aacaacgatc
    43861 ccttctgtct cttcataaga agggaaaaag aatagatctg cacctgaata cgcaccttct
    43921 atgatctctc cacgaatgta accaggaaac aggacatttt caggatgatc ttcttttaca
    43981 attttccgga tgttccgagg aatcgagtac atgggaacat gaccaaacca aataaatgtg
    44041 tattcgggca tcttcttagc aatttctacg aaatcaatga ttcctttacg ttcgaaaaac
    44101 aaaccgacac aaatgattac tttttgatcc ggagacagtt tgaaatattc tctgaacttt
    44161 tgttctttca ttggatcagg gtgatatttc tctaagtcga tcccattgga aatagcttga
    44221 atcggcacac ggataccata gctttccaac aactgttttg aataaggtgt tggcgtgatc
    44281 agatagtccg ctttttggta caatcctacc agatattttt ttacgatagg agaaagctgg
    44341 ttcgatccga taaaggaatt tcggaaatct tcctctgtag aatgcgcatg atagacaact
    44401 ttttttcctt ctcttctggc tttattgacc atattatgac tattgattcc gtatgtattg
    44461 atgtgcagga tgtcataatc ttctttttca tctagtgtat aagagatacc gacttccgtc
    44521 agagcacgtt tttgatgatc aagcgcacgc ccgattccag attttgcaag catcttttca
    44581 ctttcaaaat ataataatac cttcacctta cgtccccctt cacttatata gtataacata
    44641 gcctacaaac tgtcactcaa acttaagccc tatttttgtc tattcttact gacaaaaacg
    44701 ttttcttaaa aaagaacaaa
//
LOCUS       DAFEIE010000017        43085 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFEIE010000017
VERSION     DAFEIE010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.017"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            212..604
                     /locus_tag="LP345_001034"
     CDS             212..604
                     /locus_tag="LP345_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1759835.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="LP345_001035"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="LP345_001035"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBL1759836.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="LP345_001036"
     CDS             3165..4775
                     /locus_tag="LP345_001036"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBL1759837.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="LP345_001037"
     CDS             5067..5936
                     /locus_tag="LP345_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBL1759838.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="LP345_001038"
     CDS             6101..7372
                     /locus_tag="LP345_001038"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL1759839.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="LP345_001039"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="LP345_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBL1759840.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="LP345_001040"
     CDS             8763..9026
                     /locus_tag="LP345_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBL1759841.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="LP345_001041"
     CDS             9471..9920
                     /locus_tag="LP345_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1759842.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="LP345_001042"
     CDS             9977..11395
                     /locus_tag="LP345_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1759843.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="LP345_001043"
     CDS             11395..12255
                     /locus_tag="LP345_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBL1759844.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="LP345_001044"
     CDS             12429..13202
                     /locus_tag="LP345_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1759845.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="LP345_001045"
     CDS             13349..13714
                     /locus_tag="LP345_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBL1759846.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="LP345_001046"
     CDS             complement(13862..15070)
                     /locus_tag="LP345_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1759847.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="LP345_001047"
     CDS             complement(15089..15367)
                     /locus_tag="LP345_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759848.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="LP345_001048"
     CDS             15521..16216
                     /locus_tag="LP345_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL1759849.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="LP345_001049"
     CDS             complement(16658..17455)
                     /locus_tag="LP345_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBL1759850.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="LP345_001050"
     CDS             complement(17452..18636)
                     /locus_tag="LP345_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL1759851.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="LP345_001051"
     CDS             complement(18661..19908)
                     /locus_tag="LP345_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL1759852.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="LP345_001052"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="LP345_001052"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBL1759853.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="LP345_001053"
     CDS             21888..22202
                     /locus_tag="LP345_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBL1759854.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="LP345_001054"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="LP345_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBL1759855.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="LP345_001055"
     CDS             22887..23531
                     /locus_tag="LP345_001055"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBL1759856.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="LP345_001056"
     CDS             23546..23875
                     /locus_tag="LP345_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBL1759857.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="LP345_001057"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="LP345_001057"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBL1759858.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="LP345_001058"
     CDS             24863..25687
                     /locus_tag="LP345_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBL1759859.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="LP345_001059"
     CDS             25680..26027
                     /locus_tag="LP345_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBL1759860.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="LP345_001060"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="LP345_001060"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBL1759861.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="LP345_001061"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="LP345_001061"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBL1759862.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="LP345_001062"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="LP345_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBL1759863.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="LP345_001063"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="LP345_001063"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBL1759864.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="LP345_001064"
     CDS             31657..32451
                     /locus_tag="LP345_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1759865.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="LP345_001065"
     CDS             32441..34483
                     /locus_tag="LP345_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1759866.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="LP345_001066"
     CDS             34764..34913
                     /locus_tag="LP345_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBL1759867.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="LP345_001067"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="LP345_001067"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBL1759868.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="LP345_001068"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="LP345_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBL1759869.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKIFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="LP345_001069"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="LP345_001069"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBL1759870.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="LP345_001070"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="LP345_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBL1759871.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="LP345_001071"
     CDS             39330..40412
                     /locus_tag="LP345_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBL1759872.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLIPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="LP345_001072"
     CDS             40412..41215
                     /locus_tag="LP345_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL1759873.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="LP345_001073"
     CDS             41285..42025
                     /locus_tag="LP345_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL1759874.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="LP345_001074"
     CDS             42036..43040
                     /locus_tag="LP345_001074"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBL1759875.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
BASE COUNT        13853 a         7526 c         9008 g        12698 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcgcgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaaat ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaatacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttt
//
LOCUS       DAFEIE010000018        42483 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFEIE010000018
VERSION     DAFEIE010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.018"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(68..184)
                     /locus_tag="LP345_001075"
     CDS             complement(68..184)
                     /locus_tag="LP345_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBL1759876.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(257..1213)
                     /locus_tag="LP345_001076"
     CDS             complement(257..1213)
                     /locus_tag="LP345_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL1759877.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1384..1752
                     /locus_tag="LP345_001077"
     CDS             1384..1752
                     /locus_tag="LP345_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBL1759878.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            1923..2354
                     /gene="mraZ"
                     /locus_tag="LP345_001078"
     CDS             1923..2354
                     /gene="mraZ"
                     /locus_tag="LP345_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBL1759879.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            2375..3334
                     /gene="rsmH"
                     /locus_tag="LP345_001079"
     CDS             2375..3334
                     /gene="rsmH"
                     /locus_tag="LP345_001079"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBL1759880.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            3339..3740
                     /gene="ftsL"
                     /locus_tag="LP345_001080"
     CDS             3339..3740
                     /gene="ftsL"
                     /locus_tag="LP345_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBL1759881.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            3741..5933
                     /locus_tag="LP345_001081"
     CDS             3741..5933
                     /locus_tag="LP345_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL1759882.1"
                     /translation="MSLKNKIRRFMEKKNLNPINNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGIAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            5959..6921
                     /locus_tag="LP345_001082"
     CDS             5959..6921
                     /locus_tag="LP345_001082"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBL1759883.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            6935..8296
                     /locus_tag="LP345_001083"
     CDS             6935..8296
                     /locus_tag="LP345_001083"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBL1759884.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            8322..9410
                     /gene="murG"
                     /locus_tag="LP345_001084"
     CDS             8322..9410
                     /gene="murG"
                     /locus_tag="LP345_001084"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBL1759885.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            9425..10645
                     /locus_tag="LP345_001085"
     CDS             9425..10645
                     /locus_tag="LP345_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBL1759886.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            10801..12126
                     /gene="ftsA"
                     /locus_tag="LP345_001086"
     CDS             10801..12126
                     /gene="ftsA"
                     /locus_tag="LP345_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBL1759887.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            12149..13390
                     /gene="ftsZ"
                     /locus_tag="LP345_001087"
     CDS             12149..13390
                     /gene="ftsZ"
                     /locus_tag="LP345_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBL1759888.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            13407..14084
                     /locus_tag="LP345_001088"
     CDS             13407..14084
                     /locus_tag="LP345_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBL1759889.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            14098..14697
                     /locus_tag="LP345_001089"
     CDS             14098..14697
                     /locus_tag="LP345_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBL1759890.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            14712..14999
                     /locus_tag="LP345_001090"
     CDS             14712..14999
                     /locus_tag="LP345_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBL1759891.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            15048..15830
                     /locus_tag="LP345_001091"
     CDS             15048..15830
                     /locus_tag="LP345_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBL1759892.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            15851..16558
                     /locus_tag="LP345_001092"
     CDS             15851..16558
                     /locus_tag="LP345_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBL1759893.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            16820..19618
                     /gene="ileS"
                     /locus_tag="LP345_001093"
     CDS             16820..19618
                     /gene="ileS"
                     /locus_tag="LP345_001093"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBL1759894.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(19667..21193)
                     /locus_tag="LP345_001094"
     CDS             complement(19667..21193)
                     /locus_tag="LP345_001094"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBL1759895.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(21208..21855)
                     /locus_tag="LP345_001095"
     CDS             complement(21208..21855)
                     /locus_tag="LP345_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBL1759896.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(22039..22368)
                     /locus_tag="LP345_001096"
     CDS             complement(22039..22368)
                     /locus_tag="LP345_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBL1759897.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            22545..23273
                     /gene="sfsA"
                     /locus_tag="LP345_001097"
     CDS             22545..23273
                     /gene="sfsA"
                     /locus_tag="LP345_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBL1759898.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            23289..24302
                     /locus_tag="LP345_001098"
     CDS             23289..24302
                     /locus_tag="LP345_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1759899.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            24302..25579
                     /locus_tag="LP345_001099"
     CDS             24302..25579
                     /locus_tag="LP345_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1759900.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            25642..28344
                     /locus_tag="LP345_001100"
     CDS             25642..28344
                     /locus_tag="LP345_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1759901.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            28496..28813
                     /locus_tag="LP345_001101"
     CDS             28496..28813
                     /locus_tag="LP345_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1759902.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            28843..29163
                     /locus_tag="LP345_001102"
     CDS             28843..29163
                     /locus_tag="LP345_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL1759903.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            29271..30731
                     /locus_tag="LP345_001103"
     CDS             29271..30731
                     /locus_tag="LP345_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1759904.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            30799..31020
                     /locus_tag="LP345_001104"
     CDS             30799..31020
                     /locus_tag="LP345_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759905.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            31051..31233
                     /locus_tag="LP345_001105"
     CDS             31051..31233
                     /locus_tag="LP345_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBL1759906.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            31233..31646
                     /locus_tag="LP345_001106"
     CDS             31233..31646
                     /locus_tag="LP345_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBL1759907.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            31769..32950
                     /locus_tag="LP345_001107"
     CDS             31769..32950
                     /locus_tag="LP345_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1759908.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(33021..33185)
                     /locus_tag="LP345_001108"
     CDS             complement(33021..33185)
                     /locus_tag="LP345_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759909.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            33339..33412
                     /locus_tag="LP345_001109"
     tRNA            33339..33412
                     /locus_tag="LP345_001109"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33373..33375,aa:Arg,seq:cct)
     gene            complement(33481..34620)
                     /locus_tag="LP345_001110"
     CDS             complement(33481..34620)
                     /locus_tag="LP345_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1759910.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(34919..35554)
                     /locus_tag="LP345_001111"
     CDS             complement(34919..35554)
                     /locus_tag="LP345_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759911.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINSASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(35667..36302)
                     /locus_tag="LP345_001112"
     CDS             complement(35667..36302)
                     /locus_tag="LP345_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBL1759912.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(36336..36797)
                     /locus_tag="LP345_001113"
     CDS             complement(36336..36797)
                     /locus_tag="LP345_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBL1759913.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(36927..37358)
                     /locus_tag="LP345_001114"
     CDS             complement(36927..37358)
                     /locus_tag="LP345_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL1759914.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(37376..37696)
                     /locus_tag="LP345_001115"
     CDS             complement(37376..37696)
                     /locus_tag="LP345_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1759915.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            37995..38771
                     /locus_tag="LP345_001116"
     CDS             37995..38771
                     /locus_tag="LP345_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL1759916.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIVADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            38786..38989
                     /locus_tag="LP345_001117"
     CDS             38786..38989
                     /locus_tag="LP345_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1759917.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            39005..39343
                     /locus_tag="LP345_001118"
     CDS             39005..39343
                     /locus_tag="LP345_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBL1759918.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            39330..39509
                     /locus_tag="LP345_001119"
     CDS             39330..39509
                     /locus_tag="LP345_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759919.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(39552..40022)
                     /locus_tag="LP345_001120"
     CDS             complement(39552..40022)
                     /locus_tag="LP345_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759920.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            40109..40807
                     /locus_tag="LP345_001121"
     CDS             40109..40807
                     /locus_tag="LP345_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBL1759921.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            40985..41326
                     /locus_tag="LP345_001122"
     CDS             40985..41326
                     /locus_tag="LP345_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759922.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            41319..41990
                     /locus_tag="LP345_001123"
     CDS             41319..41990
                     /locus_tag="LP345_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBL1759923.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            41996..>42483
                     /locus_tag="LP345_001124"
     CDS             41996..>42483
                     /locus_tag="LP345_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759924.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GA"
BASE COUNT        14189 a         7153 c         8630 g        12511 t
ORIGIN      
        1 aaaaaggacc tgagccacct cgcagtggtt caggtccttt tcagcagctg atagctatat
       61 tttattttta catgacactc attacagcag tcaatacaac agatccaatc gttaaaatca
      121 gcattgtcca aatgacaaat tttgttactt tagcaaaagt acttgtttgt tttttttcac
      181 gcattgtttt caacctcgtc attaattagt tgattcaagt gtacaatctt ttttccattt
      241 ccacaagagg gcttttttat aaaaacttcc ctttttttaa ataataggta gttacgatac
      301 aaataaataa tgttaataga actagccata taaaggcatc atccctttca gcaataggta
      361 acttaatgtt cattccatag atactgccga cgattgtcgg tatagttaaa ataatcgtta
      421 aagaagttaa aattttcata atattattca gattattcga tacgattgct gaaaaagtct
      481 gattcatttg ttctactagt tttaattgaa tgcgagaagt agtcattgcc tgctctgttt
      541 ccaccaatac atcacgtaaa tgatttttca aagcatgatt ttcttggaaa agtttatttt
      601 gcgctagttc tttcaatgca tctaaattag cagaagtcgc ttctctgaaa taaacgaggc
      661 ttttttggat atccatgatt tgataaagtt gtttgttttc agtggatact tgaagtttgg
      721 cttccaaagt atcgcattga gattgaagcg tagctaaata actgttgtaa gagagtgtga
      781 cctgccaaat gaattgaaag aagatattga gattaggcga aatatcactt tttggaaagg
      841 tctggctaaa gactttcttt aaaaacagtg gttcatgatt cgtaattgtg ataagcttct
      901 ttttgggcgt caaaataata gagagcgggt atgtatccac ttgaaaataa ccgctaggac
      961 ttgttttagc aaaaggatat tgtaacaata ataacgctgg ctttgtcaac tttgattgat
     1021 tgaattcttc tgtacgggaa ttttctgcat cgtccaatat ggaagtgatg taatctgacg
     1081 gaatttcaaa ttgatgtgtc agctgatgaa tctcttcttg attaggacgt tctacacaat
     1141 accagatcgt ttggtcagtt tcctttccgg tattacgcag tttctcatta tctaatgtaa
     1201 aatatttgat catgattttc ctcctgttgc ctgtttcttt tattataacg gatagggaat
     1261 tggaatacat ggaatgtgtt tgtaagatat agaatataac tgcataaatt taaataaaat
     1321 gaaacagttg tgtaaagtat atacagtata cttgaagcaa cgataaaaaa ggagtttacg
     1381 ttcatgggca cattcacacc acttatcttg ttttggtata tttacccggt aatcgttttg
     1441 tttggttgcc aatttcttgt aaaattattt tcgttaaatc gtcgttttaa aataaaagcc
     1501 cctgatttgg cgattccttt tttgtggggc ggtatgcatg cattgtctag aaatacaggg
     1561 acaatttcta tcttaccgtt tttctttatt tctgttttgc taatgggaat ttgtattgct
     1621 gttttccaag catattatta tgaagaaatt atttatccgc gttatttcaa gatgacttgg
     1681 cgtttggttt ttctgttgac aatcgtcttg tacgctgtct tgatcattgt gaacatactt
     1741 tcttacctat gaaaaaaata gaaaagctgt aaaaagtctt ttaaaaggct ttttgcagct
     1801 tgatttttaa aaaaatgttt atgaataaaa aaagttgttc ccggatttcc cagaaaaggt
     1861 ggtagaaagt gggggattgt ggtagactaa ttttagttag tggaggaatg ggggggcttt
     1921 caatgttgat gggtgaattc caacataata ttgatgcaaa aggacgttta atcgtgccct
     1981 caaaacttcg tgaagaactt ggcgaaaagt ttgttctgac acgcggattg gatggctgtc
     2041 ttttcggcta tccgatgagc gaatgggaaa atctggaagc taaactgaac gaaatgccgt
     2101 tggctaaaaa agacgcacgt acttttgtgc gattcttcta ttcggctgcc actgaatgcg
     2161 aacttgataa acaaggacga atcaatatac ccagcacgtt aagaaattat gcagctttga
     2221 caaaaggttg cgtagtcatc ggtgtatcta accgaattga aatttgggat gagacacgat
     2281 ggcaagattt ttctgcagca gcagaagaga actttgacga aattgctgaa agtatgattg
     2341 atttcggact ataagaatag gaagaggctg actaatgact gaaacatttc aacactatac
     2401 agtcatgttg aaagaaacgg tagatggatt gaacatcaaa ccggatggcg tttatgtaga
     2461 ctgtacactc ggcggtgccg gacatagtga atatttatta agccaactaa gttctaaagg
     2521 gcatctgtat gcgtttgacc aagatcaaaa agcaatcgat cacgccaagc tgcgtttagc
     2581 ttcttatgtc gaacaaggta tggtcacatt tatcaaagcg aacttcagag aattagaaga
     2641 acgcttgagt gagcatgtag ataaggtaga cggcattttg tatgatctag gggtttcctc
     2701 tcctcagcta gatgaagcag aacgtggatt tagttatcat caagatgcac cgttggatat
     2761 gcgcatggat cagtcagctc ctttatccgc ttatcacgta attaatgaat attcctacca
     2821 tgaattagta aagattttct tccgctatgg cgaggagaaa ttttccaaac aaattgctcg
     2881 tgaaatcgaa cgagtacgaa aaacaaaacc aatccaaaca actggtgagc ttgtcgaaat
     2941 cattaaacaa gtcatcccag ctcccgcaag aagaaaaggc gggcatcctg caaaaagaat
     3001 ttttcaagct gtgcggattg cagtaaatga cgaactcggt gccgaagagg cctctttaga
     3061 acaggcaatc cggttattga aagtcaatgg aagaatcagc gtaatcacat tccattcatt
     3121 ggaagacaga attgtcaaaa gtatgtttaa agaatatagt acggtacaag atctaccacc
     3181 gggacttcct gtcatacctg acgaattcca accagaactg aaagtcatta ctcgtaaacc
     3241 aatccttcct tcagaggaag agctaacaga aaacaatcga tcacgcagtg caaagttacg
     3301 tattgcagaa aaaataagaa tgaaagagga gtagaatgat ggcagaatta aagaaaatgc
     3361 aagattacga atatgattta cctgaattgg tggatcagcc ggaacaacaa atgcctgatt
     3421 cttcttcgaa tcaagaaatc attcttccac aatcaccggc aaaacgatta aagcagattt
     3481 ctgctttgga aaaaattgct gtggcaagcg tggcgattgc tattgttgct ttatgtgttt
     3541 taacagttat gctgcgcaca aatatcagcg gagctgaaaa agaaatcacg tcaatacaaa
     3601 cagaaatcaa tgataaaaag caagaaaaaa cgagtttaga acaagaaaaa aacgaacttt
     3661 ctcgtactga acggattaaa caaatcgcag aagaaaaagg attgtctatt aatgacgaca
     3721 atttaaggaa agtgaagtaa atgagtctta aaaataaaat tcggcggttt atggaaaaga
     3781 aaaatctaaa tccgataaac aatcgcaaaa aagtaggtat cattttattt gctacgagta
     3841 ttggattgtt ctttttattt gccgtccgtt tctcgtatat cgttattgga ggtcatgttg
     3901 ctggtacctc attagctgaa aaaacaaaac agttgtacca aggaagtgaa gtagtaaaag
     3961 caaaaagagg aacgatttat gatcgtaacg gtgtggcgct cgcagaagat gcctcctctt
     4021 attcaattaa agcgatactc tcaaaaacat atacctctgg ggataaaaaa ctgtatgttg
     4081 aagaaaagaa ttttgataaa atagcagaaa tcctgcataa gaatctttct atagacaaaa
     4141 aagatgcact gaatatttta gaggacggcg caaaaaaaga gctgtatcaa gttgaatttg
     4201 gtagctatgg gaaaaatatc tcccaagaaa ccaagcaaaa catcgaagcg gacatgaaaa
     4261 aagaaggtgt cgctggtctt tattttgtcg accatcaggc tcggatgtat ccaaatggcg
     4321 tcttttcttc tcattttatt ggatacgcag ttccagacaa agatgagaat ggcttagttg
     4381 gtaaactagg tttggagtct gcttacaatg atatcttgag cggtaaagat ggtaagatta
     4441 tttatcaaaa agataatttt caaaatcctc tgccaggtac agtggcagaa gaagaaaaag
     4501 ctgtcgacgg acaagatatc tacacgactt tagacagcag actacaaagt tatttagaaa
     4561 cactgatgga tcaagtaaat gaagaatatc agccagaaga attgacagca gtcctgatga
     4621 aagcaaaaac cggagaaatc ttggcaatgg gacaacgacc tactttcaat cctgaaacaa
     4681 tggaaggatt gactggaaaa gatgctatct ggcgtaattt cttggtacaa gatagttatg
     4741 aaccaggatc aaccatgaaa gttttcacta ctgcagctgc tatcgaagaa ggagaattca
     4801 acgagaatga aaccttccaa tctggaaaaa tccaagtaga agatgctacg atcaatgacc
     4861 atgactttgg tgaaaaaggt gtgctgacca tgcgtcaagc tctttcatgg tcaagtaacg
     4921 tcgggatggt catactggaa cagcgattag gcggacgatg gtataactat ttacaaaaac
     4981 tgggatttgg acaaagtact cattctggat tagatgatga agtaaacggt gctttaccta
     5041 cattaaatat tgtcgaccga gcaatgagtg cttatggaca agcggtaggt gtgacgaatt
     5101 tccaaatgat gaaagctttc acttctattg cgaataacgg tacaatgatt caacctcgat
     5161 atatcagcaa agtggtggat ccccaaactg gagaagagcg aacaactcaa acagaagttc
     5221 tagggcaacc tttttcaaaa gaaacaacag aaaaagtccg tgaatatatg agagatgttg
     5281 tcgaaagcga aaactacggt agtgcttatg gtgtatatag tgtacctgga tacaatgtat
     5341 cggcaaaaac cggaatagcc caaatcgctt ctgatacagg gggatatcaa acaggagata
     5401 cagcctacct gtattcgatt gtggagatgg ttccttctga agatccagac tatgtcttgt
     5461 atctaacaat gaaacaccct aagacatatg atcgaatggc attggctaaa atcgcaaatc
     5521 cattgatgaa acgggcaatg gattttaaag aaactgaaga agattcagat acagaaacaa
     5581 aaacagaaaa agtatccgta gccgattatc gtaatcttga agcggacgtt gcagcagctg
     5641 atgctcaaaa aagtggactg caacctgtag tgatcggtaa tggtaaaaaa gtacaaaaac
     5701 aatctactgc caacggtgat cagttgatct ctggagaaaa actgatccta tatactggtg
     5761 gtgataagct gatgcctgac gtaacaggat ggtcaaaagc agatatcatg aagctgggga
     5821 aaatcctcgg tattgaagtt agttttgatg gagatggtta ttgtgtcaaa caagaacttg
     5881 ctccatatga aaaaatcact gaagacaaac ttagttttac tttagaagaa taagaagaga
     5941 aataggagag aaaagagcat ggaatggaca caagcattga ttcccattgt cagcagttgt
     6001 gcaatgacaa ttgccgcaat gccgctattt attggttatt ttcaaatgaa aaagcaaggt
     6061 caggcgattc gtgaggaggg accaaagtgg cacaatagca aagccggaac tcctacaatg
     6121 ggcggcttag tgtttctgat cggctctatt ttgacaggaa tttgggttgg agcttggcaa
     6181 aaacagctaa ctcctactct tttcatcttg ctttttgtat tagcgttata cggagtaatc
     6241 ggctttcttg atgattttat aaaaatattc aagaaaagaa acatgggact gaactcgaag
     6301 cagaaattga ttggacagat tctaggggga atcatctttt atcttgttta ccgttctgaa
     6361 ggttatccag gtgtattgaa tttcttcgga ctagatctac ctttaggaat catttatggt
     6421 attttcgctc tcttctggct tgttggattt tcaaatgcag taaatctgac agatggcatc
     6481 gatggattag ttgctggctt aggaagtatc tcttttgcag cttacggtct aattgcttgg
     6541 catcagcatc agtatgatgt attaatcatt tgcttaagtg ttttaggagg tttactgggt
     6601 ttcttcgtct acaacagaaa acctgccaag atttttatgg gagatgtcgg ttcattagcg
     6661 ttgggcggac ttttagcggc aatttctata atgctaaacc aagaatggac attgcttttg
     6721 attggtttga tctatgttat ggaaacagca agtgtgatgc ttcaagttac ttcctttaag
     6781 cttacaggaa aacgaatttt taaaatgtct ccaattcatc atcactttga aatgtgcgga
     6841 tggtcggagt ggaagattga tacagttttt tggttgatca gcattgtgac ttcgttgatc
     6901 acattatgga tcgtttggta ggagatgacg ggaaatgaaa aaaatatcaa catatgaaaa
     6961 taagaaagtg cttgtcttag gactcgcaaa aagcggagta agtgcggcca aattattaca
     7021 tgaattgggc gcacttgtca ccgttaatga tggaaaacct tttgacgaaa atccggaagc
     7081 acaagagctg ctttctttag ggataaaagt aataacaggt agtcatccaa tcgaattgtt
     7141 ggatgaagaa ttttcattga tggtcaaaaa tccagggatt ccctacagtc atcctttagt
     7201 agcaaaagcc caagaaatgg gtattccggt aattacggaa gttgagctag cttacgaagt
     7261 agcggaatgc ccaattattg ggattacagg aacgaacgga aaaacaacga caacaacgat
     7321 gacaggacta ctactgaatg caggagcaga tcaaggaatt gcacgtttag cgggtaatat
     7381 tgggtatcca gcaagtggtg tagcgcaaga agcaaaatca gaagataaaa ttgtgatgga
     7441 attgtctagc ttccaactca tgggaatcac agatttccgc cctcatatag cggtgattac
     7501 caatatctat gaagcacata ttgattatca tggtacaaga aaagaatatg tcaaagctaa
     7561 atggaacctt caaaaaaaca tgacagaaaa agattatctg atccttaact ggaatcagtc
     7621 agaactacaa gaattagcgc aaagaacaaa agcacgcgta ctgcctttct cgacaaaaga
     7681 agtgttggaa gacggtgtgt atgctgacga ttactcaata tactataaaa aagaaaaaat
     7741 aatggaaata tctgaacttg gcgtaccagg taagcataat gtagaaaatg cactagctgc
     7801 tatttctgta gcaaaattgt atggtatatc aaatgaagct atacgagaaa cgttgcattt
     7861 tttccatggc gtaccacatc gtacgcaata tgtaggagaa atccaaggca gaaaatttta
     7921 taatgattca aaagcaacca atattttagc gactaaaatg gctctaagtg gatttgaaac
     7981 gtctaaggtc gtgttattgg ctggcggatt agacagagga aatacatttg atgaattaat
     8041 tccttcatta aaaggaatca aagcaatggt cgtatttggc caaacaaaag aaaagttgat
     8101 ggatgctgga aaaaaagcag gcatcgagac aatagtaaca gccgattctg tagaacaagc
     8161 agttccttta gcattagaaa acagtacaga tggtgatgta gttttattat caccagcgaa
     8221 tgccagctgg gatcaatacc caaattttga aactagagga aacagattca tggaagctgt
     8281 gaaccgatta aaatagaaaa agtagaagcg agcgataaaa aatgaaaatt ttggttacag
     8341 gcggaggaac agggggacat atttatccag ctcttgcctt tgtcaattat gtaaagactc
     8401 aagaaccgaa tgctgaattc atgtatgtgg gagcaaaacg aggtctagaa aacaaaatcg
     8461 tccctgatac aggaatgcct ttccatacct tggagattca aggatttaaa cgaaaaattt
     8521 ccatgcataa catcaagacg gtccgattgt ttcttaagag tatccgtcaa gcaaaaaaaa
     8581 tcctcagtga ttttcaacca gatatcgtta tcggtactgg aggatatgtt tccggagcgg
     8641 tagtgtacgc tgcagccaaa atgggtattc caacagttat ccatgaacaa aacagtgtac
     8701 caggtgttac caataaattt ttaagccgat atgtggatcg gatcgctctt tcatttaaag
     8761 atgcggcttc cttttttcct gaaaacaaag cagttcttgt aggtaatcct cgagcacaag
     8821 aagtagcaga tactaaaaaa tcagatattt tgaaaacatt tgatttggat ccagaaaaga
     8881 aaacagtctt gatttttggc ggtagtcaag gagcacttaa aatcaatcaa gcagtatcag
     8941 tttttttaag tgaatatatt ccttcttctt accaagtttt gtatgcttca ggagatagat
     9001 attatgaaga gatcctaaat aaaataaatc ctgaaataca aaatattagt gtccagcctt
     9061 atatcaaaaa tatggcagag gtcatggctt ccagtgatct gctggtgggg cgtgctggtg
     9121 caacttcgat cgcagaattc acagctctgg ggttaccggc agtgttggtt cccagcccat
     9181 atgttacgaa tgatcatcag actaaaaatg caatgagtct tgttcacgca ggagcagcaa
     9241 aaatgattgc agataatgaa ctaacaggtg aatcactaag tcagacagtc aacgaaatca
     9301 tgggtgatga agaattgcaa aagcaaatgt gccgagcttc taaagaacaa ggaatccctg
     9361 atgcttcaaa acgtctttat gacttagtaa aacaaataat caaaaaataa aggcggtggt
     9421 cttagtgagt aagaaaaaag aaccaaaaaa attgtctcat ccgtcttctg atgaaaacaa
     9481 tttgactcct tggcaaaagg ctaaccgaaa atatctggca gaacaagaga tgaaaaacca
     9541 agagccaaaa aaagaagaca taacattaga tacacccctt tcagattctg aagaagaaaa
     9601 aacggttcaa gaggaacagc aagaagaaag ccagtccgag aaaaaaatcg aattttttga
     9661 agagatcaag caaaagaaaa acggtggacc atataacggt tcttttttga accggctgcc
     9721 caatttaaaa agtcaacggc acaaagtact atttcgtcgg ttagctttga tcatcactgt
     9781 attgggtata ccgctgattt ttttgatcta ttatgtttct ccttatagca aattacaagc
     9841 agttgcagta tcaggcaata agacagtcaa cagccaagaa atcatctctg atacaaaatt
     9901 gtcattagga gaaaatgttt ggggacagta ttttcatcga tctacttata tcgatcgcct
     9961 taaaaaagca cagccaagaa tcgaaacagc aaatatacat ttcaaaggga tgaatgaatt
    10021 cgatttggat gtaacagaat ataaagagat tgctttgatc gcaaaaaaca atcaatacta
    10081 cccagtgatt gaaaatggaa cagtattaga tgaaaaagta gcaaatccta caaaaaatct
    10141 ccctatcttg gaagagttca aagactctgc aaaaatcaaa gaattaacaa agcaatacaa
    10201 tcagttatca tcagaattac aaaaagcaat ttctgaaatc aagtacacgc caagagcaag
    10261 caataaaaat ctgatccaat tgaatatgaa tgacggcaat caagttattg taaatatcaa
    10321 taatcttgcg aaccaaatga aatattattc gcaagtagcc aaagatatgg atgaaaaagg
    10381 tgtgatcgac atggaagttg gtatcttctc gcatccttac ggtagcactc aagaaacgga
    10441 agaatcgggc caatcggaag aaacaactga aagtgaagaa aatgcggatc aaacaaacga
    10501 atcaagtgaa gaggcagaaa cgcaaaaagc acaaacacct ggatcgtcta gcacaaacgg
    10561 atcatctgat tcaaatgatt caagtgaaac aagtcaaata gaagataatc caagtacaac
    10621 tccgtcaagt ttaaatgaaa attgataaaa caactttaaa aagtaagaat gtactttcta
    10681 aaaaccagta atttatggta gaattggaag cagtgaatat atctattaat aagtatattt
    10741 taaaacggac gctagttgtt cgcttgtata tggaatagta agtaggaggg aatcccattc
    10801 atggcaaaaa caggaatgta tgtaggcctt gatattggaa cgacatctgt taaagttgtc
    10861 gtggctgaat atatcgacag ccaaatgaat attattggag taggaaacgc aaaatcagaa
    10921 gggattaacc gaggcattat cgttgatatc gataaaacgg tccaagcgat acaacgagca
    10981 gtacgacaag cagaagaaaa agcaggtatc cagatcaaag gcgtaagtgt cggtttgcca
    11041 gcaaacatgc ttgaagtaga aaattgccag ggaatgattg cagttaacgg agattcaaag
    11101 gaaatcaccg atgaagatgt cagaaatgtg gcttcagctg cccttgttcg ttcaatacct
    11161 cctgaacgtc aaatcgtgtc aatattgcca caagatttta ctgtcgatgg gttcgaggga
    11221 atcaaagatc ctcgtggaat gatcggcgta agattagaaa tgtacggtct gttgtttaca
    11281 ggacctaaaa cgatcatcca taacatacgt aaatgcgtgg aaaatgccgg attaatcgtc
    11341 aacgaaatgg tgattactcc tttagcgctg actgaatcaa ttctttctga cggagaaaaa
    11401 gattttggta cgatcgtcat tgatatgggt ggcggccaaa caacaacggc tgttatgcat
    11461 gataagcaat tgaagtttac caatcttgac caagaaggtg gcgaatttgt cactaaagat
    11521 atctctattg tattaaatac gtcatttaac aatgcagaag cgttgaaaat aaactacggg
    11581 gatgcatacc cagaacggac atcaccagat gaagaatttc cagtagatgt gattggtcag
    11641 tcagaaccag tgaaagtcga tgaacgctac ttgtcagaaa ttatttcagc tcgaatggaa
    11701 cagattttca acaaagcaaa agatgcattg gaccaaatcg aagcattaga gttgccaggt
    11761 ggcgtcgtat tgacaggcgg agctgctagt cttcctggtg ttgtggactt ggcacaagaa
    11821 atcttcggcg taaatgtaaa attgtatgtt ccaaatcaca tggggctgag aaacccggta
    11881 tttacaaatg taataagtat cgtggattat tcagcaaact tgagtgaagt gtatcaattg
    11941 gcaaaaattg ctgttacggg tgaaacctca gcagctcgtc aaatggtagt tgaacaagaa
    12001 acaacaaaca catatgagag ctatgaagca cctgaagaaa caatctacga tgagccggaa
    12061 ccaaaagagt ccggagaaaa tgtaaaaaat aaaatcaagg gtttctttac aaatattttt
    12121 gattaattca tcctgggagg aataagatat ggaattctca attgataata atatcaatga
    12181 cggcgcagta atcaaagtca tcggagtcgg tggtggcggt ggaaatgctg taaaccgaat
    12241 gattgaagaa aacgttaaag gtgttgaatt cattacagcc aacacagacg tgcaagcatt
    12301 aaaaaattca aaagctgaaa cagttatcca attaggcccc aaatatactc gtggtttagg
    12361 tgctggttct cagccagaag ttggacaaaa agcggcagaa gaaagtgaac aatccttacg
    12421 cgaagcttta gacggtgcag atatgatttt catcactgca ggaatgggtg gaggaaccgg
    12481 tacaggtgct gcaccaatcg ttgcaggtat cgcgaaagaa ttgggcgcat tgactgttgg
    12541 tgtcgtgaca cgtccattca cttttgaagg accgaaacgt ggccgttttg ctgcagaagg
    12601 tatcgctcgt ttgaaagaaa atgtggatac attattaatt atctcaaata accgtttatt
    12661 agaagttgta gataaaaaga caccgatgct tgaagctttc cgtgaagcag ataatgtttt
    12721 acgacaaggt gtacaaggta tctctgattt gatcacagcg ccaggttacg ttaaccttga
    12781 ctttgctgac gtgaaaacag tgatggaaaa ccaaggtaca gcattgatgg ggatcggtgt
    12841 ggctagtgga gaagatcgcg tagtagaagc aacgaaaaaa gcaatctcct ctccattgct
    12901 tgaaacatct attgatggag ctgaacaagt acttcttaac atcacaggcg gtttggatat
    12961 gacattgttc gaagcacaag atgcttcaga tatcgtagca aatgcagcaa ctggcgatgt
    13021 aaatatcatt ctaggtacat ctatcaatga agaaatgggc gatgaaatcc gtgtgacggt
    13081 catcgcaaca ggtatcgatg aatcaaaaaa ggaacgcaag tctagccgac cagctagaca
    13141 agcacaaatg caatcacctg ctcaaaagac tgtattagat atggatcaag ctaaaccaac
    13201 ttcttcagaa gaagaaaaca gttttggcga ttgggatatc agacgtgaac aaaatgttcg
    13261 tcctagagtt gatgattcca attttgacaa tatcgaaaaa aaagaatttg atacattcaa
    13321 ccgcgaagaa acaaaatctc atggcgatga tgaattaaat acgccaccgt ttttccgtcg
    13381 taaaaaataa aggagaggaa gagcacatga ttgctgacaa cttgcagaaa atcaagcaag
    13441 aaattcagga ttcgtgtgct cttgttcatc gtgatccgaa agaagttaca ttagtagctg
    13501 taacaaaatc tgttgaatcc gctcaagctg aagaattggt tagagctggc gttatgaatt
    13561 gtgcagaaaa ccgagtagat aaattattag aaaagaaaca agatttattt gattttcctg
    13621 aaataaagtg gcatttaatt ggtaatttac agcgcagaaa ggtaaaattg attgtaaatg
    13681 aaattgatta ctttcatgcg ttggacagtt taagattagc agaagaaatc cagaagcggt
    13741 tagagaaaga attatcctgt tttattgaag taaatgtttc tggtgaggaa tcaaaacatg
    13801 gaatttcacc agatgagctt ttaccgtttg tggaatcttt agctgcctgc acaaaaatca
    13861 aggttgttgg gttgatgact atggcgccta aagaagcttc tgatgagcaa atccataaag
    13921 tgtttggtac gctgaaagaa ttgcgtgatc ttgttcaagc aaaaggttat gcccatgcac
    13981 catgtagtga attaagtatg gggatgagtc aagactttca aattgcgatt gaagaaggtg
    14041 caacatttat ccgtgtagga acagcgctat tcaaagacga ataaaggagg aacaaaaatg
    14101 ccgcttttaa acagaggagc aattgctaat tttttcggat tagctgatga ggaagagtac
    14161 gaataccaag attatcctga aacaacaaaa aaggctgtac agccaactaa aaaaaataca
    14221 acacagaatc aatcaactca ttctgtatct gctgcgaata ctcatgaaaa acaaaaaacg
    14281 gcgacttcac gtcctgtaac gcatgaaagt attcagccgg ctgaaaagaa aaaagtaatt
    14341 gaactacatc aatcacctac aaaaactgta gcgaaagaaa gaacagcttc aagaacctct
    14401 acacaaccta aagcaaatct tgctggaaaa atcactgtaa tggaaccaag agcttattct
    14461 gaagctatgg cgattgctaa acgaatcatt gctggagaag caaccttagt gaattttcat
    14521 ttagtagaag aaaaacaagc gagaagaatc gttgattttc taacaggaac agtttatgca
    14581 ctagatggag atatcaaacg tgttggagat gagatttttc tttgtacacc gactgggatg
    14641 gagattgaca gttcaaccgc tcaatctttt gcagatgcga atttgtttga tctgtaagag
    14701 gaggaactac gatttatact attgcactat tacttcattt acttcaacgg gcagcctatt
    14761 tctatagcat tatcttgatg gtatatgcat tgctctcttg gtttccaggc gggtatcaat
    14821 cagggctagg acgattatta gctaagatct gcgaaccgta tatcagtttg ttcgatcgtc
    14881 tgcctttgag gattggaccc ttggatttca caattttagg ggcaatcctg atcttgaact
    14941 tagccgtaca aggtttagca cagatcgtta tatggataac tgtccattta gtttattgat
    15001 tgaagcaaca aaatctttat tctcagaata gataggaggg gaaaattttg gatgcaaatg
    15061 tataccagca ctttcgggca gatgaacgta catttatcga ttcggtaggc gattggattg
    15121 aacaggttca aggacaatat gcaccctatc tgaccgaatt tcttgaccca agacaatcct
    15181 atattttaga aacactgatt cgacaaagca gtgatttgcg tttcatgttt tatggcggat
    15241 atgaacaggc agaaagaaaa agatgtttga ttttccccga ttattacgaa cctgtagagg
    15301 aagattttga aacagcattg tatgaaatcc attatcctag caaatttgcc agcctaagtc
    15361 atgggaaaat ccttggaact ttagtgggaa cggggatcaa acgctcttac tttggcgata
    15421 tcatctcgga cggtgatcgc tggcaagtat ttattgcaaa tgaggtggat cattttgttg
    15481 ctgcacaagt aacaaagatt ggaaaggttg ctgtacgctt ggaaccaatc aaatacacag
    15541 aaatgattat gccgaaagat agctggacac aagaaagagg aacagttagt tccatgcgac
    15601 tagacagtgt gatctctgag atttataata tttccagaca gcggtccaag cagctgatcg
    15661 aagctggtaa agtaaaagtg aactggacag aaaatacaag acctgatttt gtacttgaac
    15721 tattagatat tatttcagtc agaggttatg gcagagtcca gatccaagaa cttgagggga
    15781 agacgaaaaa agaaaagtac agggtactgt tcggtgtatt acgtaaataa aataaaaagg
    15841 tggtttactc atggctttaa ctccattaga tatccaaaat aagacattcc cgacaaaaat
    15901 gcggggatat aatcaagacg aagtagatga tttcttagat ttagttgttc gtgactatga
    15961 ggaattgact caaagaaatc gagaattaga aaaagcagtc aaacattctg aagaaaaact
    16021 tgagtacttc aatgaattaa aagatgcttt gaaccaatca atcatcgtag ctcaagatac
    16081 ggctgataaa gtaaaaacaa gtgcaagcaa ggaatccgaa gtgatcgtta cttctgcaca
    16141 aaacaaagca gatgagttag ttgcgaacgc tgaaaaacgt gcacatcaat taacaactga
    16201 tgcagaagaa aaagcaagaa aaatcttgac agatgcaaca gaaaaagcaa gacagcttgc
    16261 gacagaaact gaagatctta agaaaaaaac acgagtattc catcaacgta tcagcttgat
    16321 gcttgagtct caattagaac aagtgaaaag tccggaatgg gatgaaattt tacaaccatt
    16381 ctccagctac gtgactgaca gccatgaagt gatcaaagaa gttttagcaa aacagcttga
    16441 caatgaaaat gatactgatg taaactcaga cacaggagtc atagaagcac ctatgacggc
    16501 atttgataca caggctattg atatctcgat cgtgcctggt gaaaatgaaa acgagtagaa
    16561 cagaaaagca ctttgttatt cttaaagcga gccgatgaga gtggaagttc ggtaagacac
    16621 tgcatggtga aagatcctct acttgagacc tgcttttccg aaattagagt aagaagcagc
    16681 ggctgacctc gttattggtc acagagagtt tgcactagat agatgcaact aaatttgggt
    16741 ggtaccacgg catgttcgtc ccttgcggct gaacatgctt ttttgtgtcc ggaaaacaaa
    16801 taaaggagtg tatggttgaa tgaaaatgaa agaaaccttg caattaggaa aaacaaaatt
    16861 ccctatgcgt ggtaatttgc caaaccgaga aggcgagtgg caaaaagaat gggaagaaaa
    16921 tcgaatctac caaaaaagac aagagttgaa cgaaggaaaa cctagctttg ttcttcatga
    16981 tggacctcca tatgccaatg gtaatatcca tttaggacat tcattgaata aaatcagtaa
    17041 agacattatc attcgttcaa aatcaatgtc tggctatcgt gcaccatatg ttccaggatg
    17101 ggatacacat ggattgccga ttgaacaagt attggctaat aaaggcgtga aacgtaaaga
    17161 aatgtccatg gcagaatact tggaaaaatg tcgtgaatat gcactttccc aagtagataa
    17221 gcaacgagca gatttcaaac gcctaggagt tgcaggagat tgggaacatc cttatgttac
    17281 attagatcct tcttatgaag ctgcacaagt acgcgtattt ggtaaaatgg ctgaaaaagg
    17341 ctatatttac aaaggattga aaccaattta ctggtctccg tcaagtgagt cttctttagc
    17401 ggaagctgaa attgaatata aagatgtaaa atctccatct atttttgtag ctttcaatgt
    17461 caaagacggc aaagatattc ttgatgaaga tacagctttt gtcatttgga cgacaacacc
    17521 atggacattg ccagcaaacc aaggtattgc tgtaaatcca aaatttacgt atgtattggt
    17581 ggaagccgat ggccgtaagt ttgtcgtagc gaaagatttg ctagaaacag tccaatcaga
    17641 aatcggttgg gaaaatgtaa cagttctaaa agaatttgct ggacaagaaa tggaatatat
    17701 gactgcaagt catccattct atgaacgtga atcacttgtg attttaggcg atcatgttac
    17761 tttagacgct ggtactggat tagtccatac tgctccagga catggggaag atgactatat
    17821 cgctggtagc aaatataaac tatctgtagt gtcacctgta gactcaaaag gattgtttac
    17881 agaagaagca cctggatttg aaggtatctt ttatgacaaa gcaaatccta tgatcactga
    17941 tctattaaaa gaaaaaggag ctttgctgaa gctagatttc tttactcata gttatcctca
    18001 cgattggcgg acgaaaaagc ctgtgatcta tcgggcaact ccacaatggt ttgcatctat
    18061 cgataaattc cgtcagaata ttttggatga agtagaaaaa gtagagtggg ttatcccatg
    18121 gggtaaaaca cgtttgtata atatgatccg tgaccgcggc gattgggtaa tttcccgtca
    18181 gcgtgcatgg ggagtaccac ttccgatttt ctatgctgaa aatggagaag caatcatcac
    18241 accagaaaca atcgaacatg tggcaaaatt atttgctgaa catggatcaa ttatctggtt
    18301 tgaaaaagaa gcgaaagaac ttcttcctga aggatttacc cacccaggtt ctcctaatgg
    18361 cgaatttaca aaagaaaaag atatcatgga tgtctggttt gattctggtt cttctcatga
    18421 agctgtttta cgtcagcgac cagaattatc attcccagca gatatgtatt tagaaggatc
    18481 agaccaatat cgtggctggt tcaactcaag tatcacgact agtgtggcta tcaatggtgt
    18541 agcaccatac aaatcagtta tttctcaagg atttgcttta gatggtgaag gccgtaagat
    18601 gagtaaatct ttaggaaaca tcattgcacc agaaaaagtg atcaaacaat ttggtgcaga
    18661 tatccttcgc ttatgggtat ctagtgtaga ttatgaagca gatgttcgtg tttctatgga
    18721 tatcttaagt caagtggcag aagtatatcg taaaatcaga aatacgatgc gtttcttatt
    18781 agcgaataca gaagatttcg atcctaaaaa agatactgtt tcgtacaatg atttacgttc
    18841 tgtagacaaa tatatgaccg ttcgattgaa ccaagtaatc aaagaaatcc gagaagaagg
    18901 gtacgacaaa tataacttca tgcatattta ccgtacagtt atgaacttct tgacggttga
    18961 tctatcgtca ttctacctgg attttgctaa agatgtagtt tatattgaag cagaagatga
    19021 ttatcaacgt cgttgcatgc aaactgtttt ctatcaaaca gctgtagctt tgacaaaatt
    19081 attgactcct atcattccgc atacagcaga agaaatctgg tcattcctga aagaagaaga
    19141 ggagtacgtt cagttaagcg agtttcctgg ttatgaagag tttgcaaacc aagaagaatt
    19201 gatggatacc tggactgctt tcatggactt ccgtgataat gtcttaaaag cattggaaga
    19261 agcaagaaac agcaaattga ttggtaaatc tttggaagca aaactaactg tttatccaaa
    19321 acaacaagtt cgtgaaatgt taaaagcttt ggatgcagat attgcacaat tattgatcgt
    19381 ttcaccagac tactttgaag ttatggcagc agatgaacaa gtgccagata acgctatggt
    19441 atttgatgat gttgctatta cagtggaaaa agcagacggg gaaacttgcg atcgctgtcg
    19501 ccaagttcgt aaagatgtag gagtagatga aaaacttcct catctatgcg gtcgttgtgc
    19561 aaaaatcgtt gaagacttct atcctgaagc tgtagctgaa ggattcgaag aaaagtaaaa
    19621 gggaaaaggg ggtgtgacat gttctttgtc acaccccctt ttgttatcaa tcgtttaatt
    19681 ttccacgttc acgataccag ttatctggtt gccagatcca ttcgaatccg tctttttcaa
    19741 gtagttcgaa agctgcttta ggtcccattg atccagcttt gtagttggga aaatccggtt
    19801 gtgtttggtc ccaagctttt cgaatgacat ccacgatatg ccaagattga gcgacttctt
    19861 cccaatgaga gaagttcgtt ccatcaccat tcaacgcatc taatagtaat ttttcgtaag
    19921 cttctgggct attttcaacc atttctgcac tatttctaaa ttccaatttg attggttccg
    19981 tttcaaatcc ttgccctact tctttcccat tcaaggataa agaaaatcct tcagttggct
    20041 gaatatagat cgttagaaca ttaggtggaa gtgtcgtatc gtcacatggt tcatcgacag
    20101 atgttttgaa tacattaaca ggaacttgtt tgaatacgat gttgatccga gtcccttttt
    20161 cagtcaaacg tttgcctgta cgtacataga aaggaacacc tgaccaacgg aagttatcga
    20221 tagtgaattt gcctgcgacg aatgtttcag tctctgattg agcatccact ttgtcttctt
    20281 cgcgatagcc cttgaattgt acaccatcca attcaccttg agcatattgc ccgcgaacga
    20341 agttttctaa cacttcttct tcgttataaa tgcggatagc tttcaatgct ttgatctttt
    20401 ctgtacggat ttctttttcg gaaaatgcta ctggcggttc cattgcaagt aatgctacaa
    20461 cctgtaaaat atgattttgc accatgtctt taagtgcgcc actatgatcg tagtagcccc
    20521 cgcgatcttc tacaccgagg ttttcgccaa aagtaatttg gatattgtcg atatagcgat
    20581 tgttccattg agcctcaaaa atattattgg caaaacggat agctgagatg ttttggatca
    20641 tttcttttcc taaataatga tcaatcctga aaatatcttg ttctgggaat acttctctga
    20701 tttgctggtt caattcaaaa gcagactggt aatcagaacc gaacggtttt tctatgatca
    20761 aacgattgaa gccatttttt gtcataatat tttgtgattt caaatgagaa acgatcgttc
    20821 caaaaaattg aggtgccata gccaaataat agacacggtt accgtttaat tgatagtgtc
    20881 catctaatcg gtcagacaat tcttttaatg tctgataatg cgttgaatca tttacatcat
    20941 gggattgata gtaaaaatgg cttgcaaagg tagttgcttc ttcatctgaa ggattcaatg
    21001 cacggattgt ttctttgaca acttcacggt agtgctcatc gctccaggga cggcgagcgg
    21061 ttccgattac agcaaaatgc tcgcctaaat ttccttttct gtaaaggcgg aacaaagacg
    21121 ggtacaattt acgctgggct aggtcacctg taccgccgaa tatcgtaaac aatacatttt
    21181 tttcattaga catgtggata cactccttta tattttatcg acaaaaatcg tgctggccgc
    21241 cttaaagctg acggggattt tctttctatc attttggata gtgatcggtc cttcataagc
    21301 tgcgatgtca acgatctcat attcttcgtt gatattcagg tcaatagtga ctaagtaatc
    21361 caacaattct ttttcatcaa gcactcgtgc gatacgcact tttgtaccga caggatagga
    21421 ctccaatgtt tgtcggcgtt cttcatggac aacttcctct tttttaggaa tcgatcctcc
    21481 atgaggacaa tgttcaggat gattcaaata gttttctaaa tgatctgcaa gatgttccga
    21541 agtcacatgt tccaatactt cagcatcatc atggacttca ttccagctat agtctaaatg
    21601 ttcaactaaa aaaacttccc ataagcgatg tttgcgaatc agactgctag ctttttgcag
    21661 tccgcttgca gtcaattgta caccttgata aggggaatgt tctacaagct cttctttcac
    21721 aagtttagaa atcatttcac tgacagatgc agctgagaca tctagactag atacgatttg
    21781 tttattgttg actttcgttg tatctccacc tagttctaaa atgattttca aataatcttc
    21841 tcgatttggt gtcatattcg atcatccttt catggtaaaa aaccatcatt agtaagtgta
    21901 acaaaaaaaa cgttaattga ctatttttct aaataaaaaa caaaggattt ttagacgttt
    21961 ttacaacaaa aaacgaaaga tgatagagaa gactcattct ttcgtttata aaggatatat
    22021 atatacattg ggagggatct atttttcaga taacaactta tatgaagtgt ctgcagattc
    22081 gtcataaaga gtttgttcgg gataagaaaa gataagataa aaaccatact gatcacgtac
    22141 gactaaacga tattcatcta tttctaccac agatgtgcca agagactgac cgttgatcaa
    22201 aaacgtgtaa tcagatgtaa tctgtaattg ttgtttttgc tggctatcac taaagaacca
    22261 tgtaccttga tactttgaga gtccttctga cttttccgct tgttttttct ttttcaagta
    22321 aataaaactt gagagaacgg taatgagtga accaagaaaa tagatcattt tttttatcac
    22381 caaatcactc ctttatgaga aaataatcgc atagacatat tctttcttct ttatttcatt
    22441 gtaccgaata aaagctaaaa tttctctaag actttcgact ggttttttta ctgtttttct
    22501 acaaattatg ataggataca tagtaggaag aaaggtgaca taatttgaag tatcagcaag
    22561 tggaaatagc tttttttatt gaccgcccga atcggtttat agcacattgt atgaaaaaag
    22621 acggagaaat aattattgcg catgtcaaaa atacaggtag aggaaaagag gtcctgatac
    22681 caggcgctga agtggctatt gtatttgctc ctggacctaa acggaaaacc gcctatgatc
    22741 tgattgctgt aaaaaagaag ggtgactggt ttaatatcga tagtcaattg cctaatcggc
    22801 tggcaattga tggtatttta gacggcacga tccttttacc aggattaact ggtccattta
    22861 cggtatacaa gcgtgaagta acttatcttc actccaaatt tgatatttat ttagagacgg
    22921 tggtcggaca aaaagcattt gttgaagtca aaggtatgac acttgaaaat aaagcgattg
    22981 gtgcttttcc tgatgcgccc acactcagag gattgaaaca tataggagaa ttaacgtatg
    23041 ccgcacaaga tggttatgcc gcttatgtct tgtttattgc tcagttcgaa catcttcatc
    23101 tggcaacgat ccatgaagaa atgcaaccag cactagctga tatggttcga catgcgcagc
    23161 aaagcggagt tcaaatcctc gcctataatt gtcaagtatc ggcagatgag gtaactgtca
    23221 agcaggccat tccatttgat gtagatatcc cttttgaaga tcctatacaa tagaaagaag
    23281 gtaaaataat gatcaactta ggtattatcg gaacaaattg gattactcat caatttgtcc
    23341 aagcagcttt aagcacaaaa aaatatgaat tgacagcggt atattctaga catttggaaa
    23401 aagcacagga atttggttct cattatgaag gggatatcga attcgcaaca gatttgaaga
    23461 cttttttcaa tattactcat atggacacca tttatattgc ttctccgaat agtcttcact
    23521 ttagtcaagc taagcaagca attttggcag gaaaaaatgt gatagttgaa aagccagctt
    23581 tttcgacgcc aaaagaaatg gatgaaatca tccatttggc aaatgaacac aatgtgtatt
    23641 tttttgaagc agcaagaaat atccatgaat caggttttaa aaagattgcc gattacttac
    23701 cattaaaaga cgagataatc ggtgcaaatt tcagctatat gaaatattct tcgcgctatg
    23761 accaagtatt agatggagaa gaaccgaata tcttctcgac tcatttctca ggtggtgcat
    23821 tgatggattt aggtgtttac cttgtatatg cagctgttgc ttggtttgga atgccaaaag
    23881 aagtccatta tttcccaaga aagatttcta ctggtgtaga tggtcttgga tgggggatct
    23941 tacgttatga gaattttgat gtatcgatcc agccaggtaa aatcggtgat tcttatttac
    24001 cgtcagagat ttattttgac tcaggaacgc tagtgatgaa tggagtcaat gcaattgaac
    24061 aagcacaatt tcatgatcgc gcgcataaag aaatcattga tttggcggta acagctgcag
    24121 aaaatccaat ggcagatgaa gcagaggatt ttgccaatgt catggctcat ccgaaagatc
    24181 cagcttgggg attgttgtat gaagagtgga tcgagctagc tagaaatgtg aaccaagtga
    24241 tttatgattt aagaaaaaat ggcggcatca aattcgatgc agataatgag gaagattttt
    24301 aatgaacgaa tttgtacaag tatttcccga aaattggcag aaaaaatatg aggataaagg
    24361 gtttatctca ccttctctta ttcaacgagc agtttttcag ccactaagta ataaacaaag
    24421 tatagtagcg gtttctccta caggttcagg taaaacactg gcttatcttt ggcctctact
    24481 actaaacgtg gaaccaggtg aagcaagtgc gttggtcatt tttgcttctt ctcaagaact
    24541 agctattcaa gtagcagatg ttgcacgtga atggggaaaa gacaaagagt tgaaagtcca
    24601 atctttggtg ggcggagcca acgtcaaacg tcagattgag ggtttgaagg aaaaaccaga
    24661 aatcttgatt ggtacaccag gaagaatatt ggaattgatg aaagcaaaaa aaataaaagc
    24721 acatcaagtg aaaacaatgg tatttgatga agcagaccag ctatttgacg ctgggaacag
    24781 ccaaatcatt gatcaaattc ttcatcaagc tccaacagag tatcagctag cttttttttc
    24841 agcgacagca gatcgttccc ttgaaagcat tgaaaaaatc actgggaaaa cgtttgagac
    24901 aattgacgtg acagcagagg acgattctcg aaaaggactg agacattact ttttacgtgt
    24961 accgatacga aagaaagatg actacttgag acgtctcacg catatagaag attttcatgg
    25021 tctgattttc tttaatcaac tgactgaatt aggcgtaatg gaagaaaaat tgctgtatag
    25081 aggtgtaccg gtaggaagtc tggcctctga tcagaacaag ctactccgaa aagcagcgct
    25141 agaacaattc aaaaagaaaa tggtcagagc acttttgacc acagatgtgg cggctagagg
    25201 tttagatatt acaggtcttc cttatgtagt gaatgcagaa gttccgttaa gtgaagaagc
    25261 ttatttgcat cgttcgggaa gaactggtcg aatgggtaat gaaggaatag taattacact
    25321 cgtacaagat aataatctaa gagatttaaa acggctttta cgtccatcaa atataacact
    25381 tgaagagatt tttttatacg gaggtaagct gcaaactgag cagccaacca aagaagatgc
    25441 agctcctgca gtaaataaaa agtatgcgaa aactttttct ggaaaggagc agaacccaga
    25501 atataacaaa gaaaaaataa gaaaaaaagt taaaaataaa tcaaaaaaag agagaaataa
    25561 aggagcaagg cgcaaataag cgccttttta tgctatgatt atgaaaacgg gaacaaaatt
    25621 ggttgccaga ggaggggtta tgtgaaagaa cgtcaagaag agatcttgca gctattgaca
    25681 gaaaaccaac aaggattgac agcaagtgat gtagctgagc gcttaactat cgatcgaagc
    25741 aatgcaagcc gatatttaag tgaactatac aaggcccatc atattgtaaa aaccgctggc
    25801 cgaccagtcg tttactcttt gccaacggaa aagtcaaaat ctgatgaagt gcatgtcgac
    25861 tcttctacgc aagtgacttt tgaaacactc gttggagaaa atgattcttt aaaagtcagc
    25921 atacagcagg caaaagctgc gattctttat ccaccgcggg ggttgcatac gattattttt
    25981 ggagaaactg gtacagggaa gtcgatgttt gctgaatgta tgtatcattt tgcaatcgat
    26041 tcagagatgc tttctgcaga tgcgccattt gtttctttca attgtgcgga ttatgctcaa
    26101 aatccgcaac tgctctttgg acacatcttt gggatcaaaa aaggggctta cacaggagca
    26161 gctcaagata gtcccggtct aatagccaaa gcagacggcg gtatattgtt tttagatgag
    26221 atccaccgtt taccgccgga agggcaggaa atgctgttta ctttcattga taaaggtatt
    26281 taccgtccgc ttggagaaag tgcacaagta catgaagcat ctgttcagat cattggggcg
    26341 acgactgaat cttcagaaag tttcttatct acgttcaatc gacggattcc tatggcaatc
    26401 accttgccga atcttgcttc acgttcactg gatgagcgtt atgaaatcat ctctcttttt
    26461 atcaaacaag aagcgaatcg tttgaatcaa cgtatcgata tcgaaaaaga agcgattctt
    26521 gccttcatgc tttatgatgc ggaaggaaat atcggtcaag tgaaacgaga cttgaaacta
    26581 gtctgtgcaa aatctttttt acattaccgt actcatcatg agaaaaagct aatcattcga
    26641 aaagaagaac tttcccttca agtacaaaaa ggattactga aaatcaagga aataccggaa
    26701 cgtctcgacc gattcatgga cagcaaaagt cagtatttga catttgaacc aggatttgct
    26761 gatgttgtct ggtcacaaga tccagaacga aacatgcagg tctataacga tattgaggaa
    26821 aaagtcactt ctctttccga aaccggtgtg gagaacattg atctagagac cctcatttca
    26881 aaagatgtgg atgcttattt ccagacatat gtcaaagaat tgactaaaag ttcgattccc
    26941 aaagatcttt tgccagatga aatctggcgg ttaaccaatc aattgtatga tgtggctgaa
    27001 aaacggttag accgtattta taatgaaaaa gctcgttttg cttttgcttt gcatctgcaa
    27061 agtacattgg atcgtgtgag agaaggtcat atgatcgtcc acccagattt gaataacgta
    27121 cggaaaaatt ttaagaggga attccaggta gcaatcgatc tttcaacgat cattgaagaa
    27181 gaagaacaag ttgagattcc ttttgatgaa atcggcttta ttagtatgtt tctttctatc
    27241 aatctaggag aaagtgagcc tgttaaagaa aacaaagtag atgttctcat attgatgcac
    27301 ggcagacaga ctgcttcaag catgttggag atggcacaag aactattagg aacaaaagta
    27361 gggaaagctt ttaatatgcc actggttatg gaagttcaaa caatgtatga agaagtgtta
    27421 caatatgtca aaaactatca agagcatttg acgaatggcc tactcttgtt aacagatatg
    27481 ggatcattaa acaccttcag tgatttgatt tatgaagaga ctggcattcg gacgaaagct
    27541 atcacgatga caagtaccat gattgtgata gaagcgatac ggatggcaag tgttggaaga
    27601 agcttagaag atatttatca aaatatccag ctttcctttg aatcgatcgt acgtgatcag
    27661 ttcaaagcgg aaaagtctga aactttacag cgtaaaaaag ccgtaatcgt gacatgcttt
    27721 actggtgaag gagtagctgc caaattatat cagcgtatta tgccagtgat taatcaaaat
    27781 aaggtagaac tgatccagat gcagttttta gaacgtgaat cattcaaaaa acacatcgat
    27841 gccttattgg aagaatatga gatcaaagca attgcgggaa cagttgatgt tgattatcaa
    27901 aatatcccat ttttttcagc ctatgacgtt tttgatgatg aaaaactaaa tattttaaag
    27961 cgtatagctg atgatgagat cccgacagct aaaattgtcg attcacttgc tggatcatta
    28021 agcgatgtct tttctattga tgaactgatc cgttcattgc aaaagacagt tcagcagatc
    28081 cagaccgatt tgtcgattat cgtggaacct ggagtagata ctggaatcgt tatccattta
    28141 gccttcatgt tagacggatt gatcaaacaa gaaagccatc ggcaatttga gaaactgtct
    28201 attttctcaa aaatttatcg tttggaaatg gatatcgttc gggcaaactt gatggcacta
    28261 gaacgaaaat atcaggtaaa aattccagaa gatgatatcg catttcttac acaaatgttt
    28321 cttgaaaata aaataaaaaa atgaacacac taatcatact gtttacacac taaacatctg
    28381 tgtgcgcact ataaaaaaga gctaaaaagc atgaaaacgc tatttcagct ctttttttta
    28441 ttggcatgct tcttgcgtta tataaaagtg taaaaaaata aaaggagtgt taaaaatggc
    28501 aaaaaaaaca atcatgttag tttgttcagc agggatgagt acgagtttat tggtcacaaa
    28561 aatgcaaaaa gcagcagaag aaaaagggat ggaagccgat atttttgcgg tctctgcctc
    28621 agatgcagat aataatttag aatctaagaa tgtcgatgta ttattattag gtcctcaagt
    28681 acgtttcatg aaagctcaat ttgaacaaaa acttgcgcct aaaggtattc cattagatgt
    28741 catcaatatg caagactatg gcatgatgaa cggagaaaaa gttcttgcac aagcagaaaa
    28801 tctaatgaaa taaatcaagt atgcagttgg gggtataaca acgtggaaga tcaacaaaat
    28861 ctagaagcca tcatggggtt aatcatgttt ggcggtaatg caaagagcga tgcaatggaa
    28921 gcgattgcgg ctgctaaaat cggtgatttt gagttagcgg ataggaaaat cgctgatgca
    28981 gaagaatcac ttatacaagc gcatcatgca caaacagaca tgttgacaca agaagcacaa
    29041 ggaaatcata tgcaagtgac attattgact gttcacagtc aagatcactt aatgacatct
    29101 attgcgttta ctgatttagc aaaagaaatc atcgaacttt atcgtcgcgt atacagcgaa
    29161 taaatacaac ttcttttttg aacggaagaa gaaaaatttt tgaacggatt ttttattttg
    29221 ttataaggag aactctcttt atataaaaaa cttataggag gaagtaaaaa atgaacggac
    29281 tatcaagttg gatggagaaa tacatcctgc cggttgccgc aaaaatcgga gcgcaaaaac
    29341 atttagttgc tttgcgtgat gcttttatcg gcacactgcc cgcaacaatg gcgggatcag
    29401 tcgctgtaat gatcaatgca attattcgtg atttaccgca acagtttaac agtacctatg
    29461 ctgacagttt agcagcagac aaaggaatct ttgccgtatt gaatgtcatc atcggaatca
    29521 atggttttgt ctggaacggt acactagcaa tcgccggatt gatctttgcc ttttcttggg
    29581 ggtataatct tgcccgagct tatggagtaa atgatctagc tggggggatc gttggtttag
    29641 ctaccttgat tcaaggtatt tcctttggtc cagcattatc agcagcatta gatgtgaatg
    29701 ttccttcaaa tgtcgcagat gcaatcaata gttctgagat tggtgcaacg attgcagatg
    29761 gcacactgtc agttggatta tggggttggc taaaactaga tcatttgaat ggaaacgctt
    29821 attttacagt tatgatcatg ggagctattt cagtcattat tttttgtaaa ttgatgcttg
    29881 ccaacattac gatcaaaatg cctgattcag taccaccagc agtatctaaa gcatttgcag
    29941 ccattttacc agcgacgatc gctttatacg tcattgctat tatcaattat atcgtaggtc
    30001 gtgtagctga tgggcaactg atcattgatt tggtgcaaaa atatattgca gaaccattcc
    30061 taggattatc tcaagggttg ggagcagtat tgatcgtcac agtatttgtt caagtattct
    30121 ggttctttgg tattcatgga ccaaatgtat tggcaccagt gctagaggga atctggggac
    30181 aagcacaact aatcaatatt gatattttcc aaaaaggtta taacggaaaa actggtacac
    30241 cagccgtgtt agatgcaatc gaagatggaa aagcttatat gtgggtccgc ggatcgttcg
    30301 atgcttttgc atggtttggc ggatcaggcg gaacgatcgt cttactgata gctatcttga
    30361 ttttctctaa acgtgcagat tatctaacag tagctaaatt atccattggg cctggtatct
    30421 tcaatatcaa cgaaccagtg atgtttggtc tgccaatcgt attgaatgca atcatgttta
    30481 tcccattctt gattgctcca gtagtagcaa cagcaattgg atggacagct acttatcttg
    30541 gcctagtcgc tccggtatcg cagcaagtca catgggtagt accgccgttc ttattgtcat
    30601 tcttagcaac aggagcggat tggcgggcac cgatcgtaac attagtatgt atggtcgtga
    30661 ctttcttgat ttgggcacca tttgtcatct ctgcaaacaa aatggaccct gccgcaggcg
    30721 aacaacaata agatgaacgt gaggagcggg acgctttaag tttcgttcct cataatgaat
    30781 tttctaggag gaactgaaat gattacaatt gccagtgcaa tgcaacaaga tgaaatcaaa
    30841 gaattgttag aaggatacaa tgaagaagga atgactttta catttaaaga aaaacaagga
    30901 atcaagctgt tctttgaaac aagtgcagaa gatccggaag ttgcggctaa aaaagcaaag
    30961 gaactaatca aagcacagcc ttggggaaca gtcctttatt ttcaatcaac agctgtttag
    31021 aaaatggttt aaaaagatag gatggttgag atgataaaaa acggtttatt tttatgtagt
    31081 attggttctt tgatcgtgtt gtatagtttg aatccacatt cgcaaaggta tgatttgtat
    31141 agtatggtca caggtctttt tctaacagga ttaggaatct atttcttcat gaaggggaaa
    31201 aaaagagaag aagcaaagga gaaaaataac taatggaaat cacgaaaaaa ttaaatattc
    31261 cagcatcgtt tttttacgat aaagttatgg actctgtcct tttcgatgta cgtaaagcga
    31321 ccggcaaatc agtaactaga aaacagctga aaaatttgga gtacgtcaaa caattctcgc
    31381 aaaataaccg ggctcgcata aaaatcgaag aagtcattga aaaccagtct tataagtttc
    31441 gtacatcgac aacgaagaat gaattcgtcg ttcattatca aatcaaacca ttggacgatt
    31501 cgacctgtga ggttcattac acagaaaaaa tggagtctta tggcatgctt caaaagttga
    31561 atgatatgct tttaggaaca atcttgatgt attttaaacg gagacgtttc aaaaaaatgc
    31621 tagatatgat cgaagcaacg tattaaatca atgaaacatg gtactattta gttattgaaa
    31681 aatgaagtaa gctagaagga atttttcata ggaagataga tctttcctgc gaatcctcac
    31741 tagctttttt gtaggaaggg gcagcaaaat gacaaacaaa gtaagagagc taggtgtatc
    31801 ttcgattgag gaaatgtttg atttagccac ttatgcattt aatggggcag atacacctga
    31861 aaggcgagaa cgttttcgta cacttgcgga gaattcttgg aattacggat tttttgatga
    31921 ggaggatcgg ctaacaagtc aagtcatggc gacccctttt ccagtgaatt tttacggaca
    31981 agagtaccta atggccggca ttggctatgt tgcttcttat ccagaagcaa ggggacaagg
    32041 cgggatcaat cagatcatgg aaaagatcct tgaagattgc cgtgatcgta aagtaagctt
    32101 atcttatctg gcgccattct cctatccctt ctatcggcgc tatggctatg aacaatcatt
    32161 tgataaaatc agttatcaac taaacagtcg tgatgtgccg tttatcaaaa aaaaatctgg
    32221 aaaaataaag cgtatggatt ttgaagatgc aaaagctgca atcagaagaa tttatgaaca
    32281 gatgccggaa aaccaacgag ctggtctgaa gcgcgaagac tggtggtata cgtataaatt
    32341 caagcaaaaa ggcaattacc agtttgcttt gcattttgat gataatgagg aagcaacggg
    32401 atatatcgtt tatcagcttg caacgtcttc ctttattatt gcggagtggg gatttttgga
    32461 tcatgatgct ttttgcagcc ttgttcgctt cgtaagttct cacaatggtg cttttgaaac
    32521 atttgaatat tcatgcggct acggcggtaa tgatcaaaat tatctattag aaaatccatt
    32581 tgcttctgta atgatcacac cttatatgat ggcgaggatc gtagatattt ctttgttttt
    32641 ggaaaattat ccatttaaaa agagacaagc tgcatttgcc ctacaaatag aagaagatca
    32701 ttatgcgaaa tggaatgaag gaatcgtgga agtaacaatc gaaaatggaa aaaatcatct
    32761 ctcaaaagta gaacaaacaa aactcccaat cgttcgagga agtatccaac atatcacgca
    32821 gctattatta gggtatcgta aagtggaaga gttggtattc caagaaagaa tacaggtgac
    32881 aaaagaatat gaagaaacgt taagctcaat cttgccacag caacagccaa ttcttaatga
    32941 ctatttttga taaaaaacgg gtgatgacaa tatttttgtc accacccttt tgtttttcat
    33001 ttggcatttg aaggaaaatg ttaaagtaaa tcctcttttt tcgtaaattt gaattttttg
    33061 ttttcttttg ttttagggtt ttcttttttg tggtcttgga ttgcttcttt cgtaatcttt
    33121 tcccgatttt ttttagatga atctaagcgt tctgcgtata ctttttcttt tggcttatca
    33181 ttcattggaa aggacctccc tacattattt cattctacct ctagtttatc atctgttaag
    33241 gactagtgga aacgttttgc ctaacttata agctgatttt tttagcagat aagcttgcaa
    33301 gtaaaaaaca aacaagctac aattgattta ttgaaattgt tcctgtagct cagtaggata
    33361 gagcaatcgc ctcctaagcg ataggtcgct ggttcaattc cagtcaggaa cgtataaata
    33421 acccctgtat cctttgcggt acaggggttt gttttgtatt tgtgccaaaa atgtgccaaa
    33481 ctagttatca tttttatata aactatcgaa cacagtattg attttttctt tatcctgatc
    33541 ttcaagctct cgaacaatat gaagataagt agacattgta gtttctaaac tgctatgtcc
    33601 taaacgtttc gatacgctaa gtatatttac tccttgataa agtaaaatag atgcatgtgt
    33661 atgccttagt ccatgcaaag taaattgctt ttcaatccct aattctttta attttttgcg
    33721 caaatatttg ctgacggcgt ttgatgaaac taatccattt tttaagttga aaaaaacaaa
    33781 attatgaggg tttttgattt caaaattctc gaataattct ttttgattga ttttaaactt
    33841 ttttaagaga tcaatcgtat gtttatcaat ggaaattttc ctatttgaag tttcgttttt
    33901 tgtttttccc cattcattta atttataatt ccatgtttta ttaatagtga tgatttgatc
    33961 ttcgaaatcg atatcttccc atgttaatcc tagaagttca gcaaatcgca ttccagtggc
    34021 accagcaact aacacgagca taggagaaga gtactgcgca gaaaggtttt cttctacgag
    34081 tttcattaaa gatttaaatt gatcataatc taaatattta tcttcttttg gcttcaatga
    34141 atcttttcct ttgattactg cttttctagt tggatcaaac ggaattaatc cttcttctac
    34201 ggcatctttc aacgacgctc taatatggtt attaaactta ataacggtag attttacatg
    34261 gtctttagca tacttattta aaaagcgttg atatcccact ctatctaaat cagaaatcaa
    34321 taccgctggc atatatttct ttatgttcat taacgtatct tcgtattttc tataagtgat
    34381 aggagatact gttccttctt tataaagttg catccaatcc tcaaagtaat ctgataataa
    34441 tagatttttg cgatcccctt taaggccttt gttcaagtta tattctaatt cgttggcggc
    34501 atcttttgct tctccttttg tcttaaatcc tgattttctt atcttcgtgt attttccgtc
    34561 atcttttttg tatgaaattt cgtattgcca actatttcca cgtttgacta atcttgccat
    34621 aattgaatca gctctctttc tctgatacaa taggaactat aaagaagccc attgtttggg
    34681 ttttattatt ttttgcacat cctttttgct tgccggcgca aggatgtgct atttgtcgtt
    34741 ttaatggtat aattggatgt gtattagatc atccaatcag aggtgtttat tatgattaaa
    34801 gtgattttta aaagaataac tgaacttcca gagtttagat tatttgttga ttattggtat
    34861 gtctggtttt ttattgttgc attgctgata ggtctagatg tcatattaga aagaaaactt
    34921 aagtaagagt tgagttaata aattgaattc ctaaatgaga tattttgtag cccatatttt
    34981 gtttgccgac atcacctaat actatggagc taatcgtttt ttctaacaga ccaaaatcag
    35041 ataatctatt taagctacca tctattagct cttgtgaata gccagacatg ctgatatttc
    35101 cagtgaaatt ttcgtttcca cgactcatta agcatgctaa caattgaatc tcaatcgatg
    35161 ttaattgatt cagtacaaga agataatact cctcgttatc ccatgaagcg ctgttaattc
    35221 gaagtaaaca attcttataa agatttttat acatatctat tttattttgt gcctttgatt
    35281 tttctacctc gtcatttatc ccttcgaata ttccaatgag ttggtccttg ttctctaagt
    35341 tgaaaacatc ttctggaatt tgatcgcgaa tgttttctaa tgattcgttt aaatttttgt
    35401 agaatttctc gatgcgtttg aaacgcttct cgtttttaga cccaaaataa agtgactgca
    35461 caacgccacc aatataagga attgctccaa taccgccttc aactattaat tcaagatatt
    35521 cttttttggt tagtttttca ttgctattat ccatagttac ctcctatttt gtcatttcct
    35581 ttacaagcat tgtgactcct gatggcactc ttttgtatag gttttattat tgtgcacaat
    35641 ctaactctta gtggggcgtg gttcatttat tttttactta ctttactatt aatcatatcc
    35701 cattgagcat aggatttttc tatgttcgat cctcttgaac taatttctcc tgtaaaagtt
    35761 actttatcgc cctttgtaaa ggtatcagca ttgtttaagt ccttcgcaaa aattacatat
    35821 gaaactttag gtgttgcaga aatatcattc caacttttat catcgtactc tttgtctgct
    35881 ataatggcta ttctagtagt cattgattcg ataacagttc cttcaaaagt atatgtttta
    35941 ccactaatat atttagtaaa agctgtattt tgctcagtag ctggagtaat agaataataa
    36001 ctatctaaga aagcacccca gtcatgatta tttgtctcta aaaattcttc aaattgagtt
    36061 aggcttttat tgctgctgtt agatgtagta gtttgagtat cagatgatga gctttcctgt
    36121 ttgttattgt catttgcctc gtttgatgag gaaagcgaga aacctacggt agtaaaaata
    36181 atcccgataa taaggagaat cataggtgtt ttcttatttg tttttttgat aaatcttaca
    36241 attaacatga ttaaacctat aataaataaa acaataccag taaaaccaaa tataccgtcc
    36301 attaatagat cctctttctc ttttgatatt gaatattata aaccaagcaa ttcttttttc
    36361 ttaaaatcga attcttcttg attaataatc ccttcatcta acaactcttt atacttttta
    36421 atttcatctg cacttgaaat ttgtgtttct ttggaattat tatctaatat agattgttgc
    36481 ttctctatat atttttttaa attttccatt tcattccaat atttttttgt aaacataacg
    36541 gtgttttcat ctttcgtggc cgctaatata cctccgcgac tttcgtttcc gcctagcaag
    36601 gtaaattgta tataaccatt actcatacct ggttttttta attgtacggc tgatatattt
    36661 ttaaagggga tagttttttc tcctttaata ccttgattaa ctaaatttat aaatcctttt
    36721 ctaataattg aaatagaatc atcagttact ttaatcaagg tttttcctgg agattttatt
    36781 aaaatctctt tttccatttt ttcttcctca tttctgtgat atgatttttt ttgtagaagc
    36841 tcatatatga ggaaagagcc cgtgttgcag cacgggcttt tttaatgttt tgctgaaatc
    36901 ggttttttta ataattcttg atgtattcat acatattgcc ttgcgtaaga atattttttc
    36961 ttaaaatagc attggcagac agcataacaa gtgtatctga gcttattctg aatagaataa
    37021 tactccataa atttttcgag attaaactga gattcatcag tcagttcgtt ctcaatatag
    37081 atatttaata aaattagaat agctatttta tctgcttctg tttcaaattt tgagtgaaaa
    37141 gttgtagaag tatcgtacaa aactgaaaat tcaaaatgag aggcgctgaa atgtgcaagt
    37201 tcatgagata aatgaaaggc ttctgcagtt tcaccgtata gattttcatt caaaaaaatg
    37261 attctgggtt ttggatagta gaaaccaggc tctttcatct ccatataaac tactttcaaa
    37321 ttgtattcgc tcaacatttc tttcaatttc aaatacatac aaaccatcac tccaactatt
    37381 cattttcctc taaagcttta gcaattgcaa tcgctttacg cattgtctcc ttagatattt
    37441 cttttccatc aaaagaaaaa acagtatcgt cttctgataa atccacatgt ttaggggttt
    37501 ctctttcttc tctacctaga aggtagtcta cagagacatc gaaatagtca gcaatccgac
    37561 ttaattcatc tgaattagga gtattatttt tccactttgc tagataaccg ttagaatatc
    37621 caaaattaat ttctaactgc cgtatagata tctttttcct cttcgccaag tcttttatta
    37681 tttcataggt attcatcgat aaaacaacct ttctaaatgt ttacaaaaaa agtttagaaa
    37741 aatacgcaga aataatttga ctaattctga gtaatgagct atactatatc ttgtaaacag
    37801 atttaacaac taaaaagaca acaaaaaaca ctattgatat gtaaatgcag accgccaaga
    37861 aagctttaaa atcaatgttt ttatgtctta tttaattatg ctcttagtat agagtattac
    37921 tcagatactg tcaattgaat ttagaaaaaa gttgttaaat ttgtttacga atataaaaga
    37981 aaggaatgag aaatatgaac acaccgcaaa tttttaattt cgaacaaaac gaagttcgga
    38041 caattttagt aaatgatgaa ccatattttg taggcaaaga cgttgcgagt gttttgggtt
    38101 attcaaacac taaagatgct ttgtcgcggc atgtagattt ggaagataag atggggtcgc
    38161 gaatcacgac ctcaggtcaa tcaagagaga tgacaatcat caacgaatct ggtttgtaca
    38221 gtttaatctt aaaatcaaaa cttccctctg ccaaaaaatt taaacgttgg gtaacaagtg
    38281 aagtgttgcc agcaattaga aaacatggag gttatctaac tccagaaaaa gtagaagaag
    38341 ctttgcttaa tccagataca atcattcaat tagcaactca actaaaagaa gaaagaactg
    38401 gaagattaat cgcagaacaa aagattgcag agtacgaacc taaaatctcc tatttagata
    38461 gcatattatc ttctacagat tcagtaacaa ttagtcagat tgtagcagat tatgggatgt
    38521 ctccacaaca gatgaataaa ttacttcata aactaggtat tcagaaaaaa gtcggtaacc
    38581 aatggttatt gtgcaaaaaa cacatgaacc aaggatacac aaaatctcat acaactgaga
    38641 tcccgaaagc cgatggtggc actaaaattg taatgaatac caaatggaca cagaaagggc
    38701 gtctatttat ctacgaatta ctaaaaaaag aaggatatta ccctcaaatg gatttagagg
    38761 aaattggtta gaaaggagtt ttagtatgac tgacattgca gaaatcactc aacgagatag
    38821 agaaaaaatc aaagaatatg tcgaaagttc aaagttctta acttacacca tgcttgctga
    38881 aagatttgga attagcaaaa gctacttatc tttaatttta aacggtaaaa agacttctgc
    38941 agaagcaaac agaattatag attcgattat cactatgtac gaattgtaaa gggaggaaca
    39001 gctaatgcaa tatctagaag caaaaatccc aattccagaa ggctatgtaa ttatctccca
    39061 agtggattat gaggagttaa aaaaagctga tgatactggt agatggatga cgttgccaga
    39121 agtgctagaa cggattaaca gaaaatatga ttggtttact tctagagttt taaagaaccc
    39181 aagatataga aatattatcg atatcgagaa aaacaaaaat ggatttgtct attatccagt
    39241 tgaaggaaga gacacatatc tatttttaag aagtaaaaca cttgaatttt tagaaacaaa
    39301 tttttcggaa atcttaagga ggcaagcgga tgggaaaatt taatagagcg ctagtgttca
    39361 gcgcaccgct aatcatctac gctttaggac tttggggaag caggcaagcg ttgataggaa
    39421 cgattgttta catggtttgg atttttatgg ggcttgatga agctgaagct gagtacagag
    39481 cgaaaaagcc aaccgagggg gctgactaaa aatgaataga aaagagaaac tagaatgtat
    39541 attactatta ctcagtttaa ttctttcact aatttctcta ttgggaagtt tgtatttttg
    39601 atatcaacaa ttttgtggat ttgggttcta tttagagtaa atatcatttt tgtttggtga
    39661 ttaaggagtt tattaaaatt aattttccct acttcaaatg caaggtaaca agatatagca
    39721 cttttaggag gaatatttag cggtacagct tcagagtata ttctattatc atcgactgat
    39781 cctcctttag caattaattt cttaaatgga gtagctgacc atctgcggtt taagttagcg
    39841 gatgaaagtt ctaaattaac taacatagct ggttctgttg aatagttaga aatgattact
    39901 tttgtataaa tcatatctgc agcgaagtaa gaagcattaa gttcaacttc tagttgaggg
    39961 cgcattcctt ttatttttat ccctgttaaa aacgtactca atataaaact tattattgac
    40021 atccattgaa aaattgttaa gtgaaaaaaa ttcaaaataa acaccaccag tttttaacta
    40081 aattatacca aaaaggagag aagaaataat gcaagaatta gtaattttga aaaataaaga
    40141 agctgtgact acgagcttac aagtggcaga aagcttcgag aaaaaacatc aacatgtttt
    40201 aagagatatt gatgcactaa aaaaagatgt gtccaatttt ggacagatgt ttgtagaagg
    40261 taatgaacca gattcatatg gcagaaatcg acgagttttc ttcattagta gagatggatt
    40321 tttcttgctg gctatggggt ttacaggaaa gaaagctatc tacttcaaac aaaaatacat
    40381 tgaagcattc aacgaaatgg aagatgttat tcgcaagaat actgttcctc aaacaattga
    40441 agatatgatg atctatcaat tagaagaaat gaaagatgtt aaaaaagatg tttccatgct
    40501 taaagatact atgcgaatta gcggacaaca agagtttgaa attaagcaaa aaggaaatat
    40561 gaaagttatg ggagttctag ggggaaaaga aagccgagct tatgaagaaa tcagcaaaaa
    40621 agtattctca aaattttggt ctgaatttaa acgtaccttt tcaatcccaa gatatggcga
    40681 gttacctcgt aagagattcg atgatgctgt ttcatttatt gaaatgtggt tgccagaaac
    40741 tgcgatccgt atggaaattg atcaactgaa cagacaacag agactttttg gtgatgacaa
    40801 tgaatagagc tgaagcgcta agaataggga cggcaattgc taattgctgg tggaaatact
    40861 ataaaccaat catcctaagc caacaacata ttgacaagca aaaagcatgg caacaaataa
    40921 aaaagtgact ccgccggcaa gcaaagagtc acaaagaaaa cacatcataa ggagatttta
    40981 gcatatggaa aaagaacttt ccactctaga tcaatatttg attgatcctg attggggcaa
    41041 gccgaaaatt gaggaaacaa gtggtcgaaa aatcagacga aatcttttga cgaatgaaga
    41101 actagcttgg gatcaagatg atttaggcaa ccatgtaact atttgggatc atgtttatct
    41161 tatccatcta tcgaagcatt cgaataaacc tgaatatatt tacgtcatcg aagatggctt
    41221 gattgatgcg ctagaagagt acgacagaga taacttgatt gatatctctt attacggacc
    41281 aggtaagaaa tacattgctg aaatggaggc agaatttgat gagtgaaatc aaagggacaa
    41341 cgaactttga aaaacttttt agtcgtaagt taaataaaat tctcaagaaa aaaggaaatt
    41401 ttgattattt atcttgggct cacgcgtggg agattatgaa aaagaatgat ccacaggcaa
    41461 cggtaactat taatgagtac aaacactaca gggttgtttc tggaactcat caagactttc
    41521 ttgttgagga atataaacct tttcttatgg atgaaactgg gacttatgta tctgtctcag
    41581 taacggttaa aggacacacg gaaaccgaat tatttcctgt tttagattat cgaaaccaac
    41641 cagttgttaa accaaatgca atgcaaatca ataactcatt gaagcgatgc tttgtgaaag
    41701 cattggctct acacggactg ggattatatg tatttcaagg ggaagatatt ccaacaccac
    41761 ctagaatcga tacaaagaaa ttaaacatgc tagagacgat tctagaagct ttcaatgagc
    41821 agatgggtaa agatatgacc aaaaccttaa tcgaatatgt taatgagcag acagataaat
    41881 tagggctctt agctgataac gttgaaacta ttgaacagtt aagctatgag caatgtgcct
    41941 tgatggagcg agcaatagca gctaagagaa aagaattaga taagaagtga tatgagtgtt
    42001 taaaccatta atcgattcat attcagcggt tctgaaaaag ttcaaaggaa aagacataag
    42061 cgcaaccatc aatgaggaag tgaacattga tcgactaaag acgatgtatg acggctacga
    42121 tggtgatcga gtcattgaaa ttcgttttat tgatcctaga cgtttcaccg tacagcaacg
    42181 aaacttcatc tatgcgctga taggcgatat ttttatcgat acaggcatgc caacggactt
    42241 ctggaaggaa ttcttctact ttcgttttga aggtgtcaca gggcgcaaaa taagcctgaa
    42301 agacgaatcg aatacaactg tgagtgatgc caatgtctta gcaaatatca tcttagattt
    42361 catctttgaa catcatattc ctttcaaaga aggctatgag attttacctg cgaatcaaga
    42421 atattacttc tacaaatgca tcacaaaaag agtctgctgc atctgtggca aaacaggagc
    42481 tga
//
LOCUS       DAFEIE010000019        41153 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFEIE010000019
VERSION     DAFEIE010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.019"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            239..481
                     /locus_tag="LP345_001125"
     CDS             239..481
                     /locus_tag="LP345_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBL1759925.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            478..948
                     /locus_tag="LP345_001126"
     CDS             478..948
                     /locus_tag="LP345_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL1759926.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            1076..2290
                     /locus_tag="LP345_001127"
     CDS             1076..2290
                     /locus_tag="LP345_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL1759927.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            3279..3488
                     /locus_tag="LP345_001128"
     CDS             3279..3488
                     /locus_tag="LP345_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBL1759928.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            3600..5213
                     /locus_tag="LP345_001129"
     CDS             3600..5213
                     /locus_tag="LP345_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1759929.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            5248..6459
                     /locus_tag="LP345_001130"
                     /pseudo
     CDS             5248..6459
                     /locus_tag="LP345_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            6482..7408
                     /gene="glsA"
                     /locus_tag="LP345_001131"
     CDS             6482..7408
                     /gene="glsA"
                     /locus_tag="LP345_001131"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBL1759930.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            7616..9076
                     /locus_tag="LP345_001132"
     CDS             7616..9076
                     /locus_tag="LP345_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759931.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            9297..11060
                     /locus_tag="LP345_001133"
     CDS             9297..11060
                     /locus_tag="LP345_001133"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBL1759932.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            11144..11602
                     /locus_tag="LP345_001134"
     CDS             11144..11602
                     /locus_tag="LP345_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBL1759933.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            11711..12394
                     /locus_tag="LP345_001135"
     CDS             11711..12394
                     /locus_tag="LP345_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL1759934.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            12541..13155
                     /locus_tag="LP345_001136"
     CDS             12541..13155
                     /locus_tag="LP345_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBL1759935.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            13171..13377
                     /locus_tag="LP345_001137"
     CDS             13171..13377
                     /locus_tag="LP345_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759936.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            13918..15048
                     /locus_tag="LP345_001138"
     CDS             13918..15048
                     /locus_tag="LP345_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1759937.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            15140..15895
                     /locus_tag="LP345_001139"
     CDS             15140..15895
                     /locus_tag="LP345_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1759938.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            15953..17992
                     /locus_tag="LP345_001140"
     CDS             15953..17992
                     /locus_tag="LP345_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBL1759939.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(18101..19252)
                     /locus_tag="LP345_001141"
     CDS             complement(18101..19252)
                     /locus_tag="LP345_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBL1759940.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(19406..19936)
                     /locus_tag="LP345_001142"
     CDS             complement(19406..19936)
                     /locus_tag="LP345_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL1759941.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(20035..20385)
                     /locus_tag="LP345_001143"
     CDS             complement(20035..20385)
                     /locus_tag="LP345_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBL1759942.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(20542..22071)
                     /gene="ahpF"
                     /locus_tag="LP345_001144"
     CDS             complement(20542..22071)
                     /gene="ahpF"
                     /locus_tag="LP345_001144"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBL1759943.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(22081..22644)
                     /gene="ahpC"
                     /locus_tag="LP345_001145"
     CDS             complement(22081..22644)
                     /gene="ahpC"
                     /locus_tag="LP345_001145"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBL1759944.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(22788..23450)
                     /locus_tag="LP345_001146"
     CDS             complement(22788..23450)
                     /locus_tag="LP345_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1759945.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            23634..25280
                     /locus_tag="LP345_001147"
     CDS             23634..25280
                     /locus_tag="LP345_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL1759946.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            25271..26353
                     /gene="uxuA"
                     /locus_tag="LP345_001148"
     CDS             25271..26353
                     /gene="uxuA"
                     /locus_tag="LP345_001148"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL1759947.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(26461..28014)
                     /locus_tag="LP345_001149"
                     /pseudo
     CDS             complement(26461..28014)
                     /locus_tag="LP345_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            28162..29303
                     /locus_tag="LP345_001150"
                     /pseudo
     CDS             28162..29303
                     /locus_tag="LP345_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(29429..30508)
                     /locus_tag="LP345_001151"
     CDS             complement(29429..30508)
                     /locus_tag="LP345_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1759948.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(30611..31051)
                     /locus_tag="LP345_001152"
     CDS             complement(30611..31051)
                     /locus_tag="LP345_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1759949.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(31108..31517)
                     /locus_tag="LP345_001153"
                     /pseudo
     CDS             complement(31108..31517)
                     /locus_tag="LP345_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
     gene            complement(31697..32131)
                     /locus_tag="LP345_001154"
     CDS             complement(31697..32131)
                     /locus_tag="LP345_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1759950.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(32231..33079)
                     /locus_tag="LP345_001155"
     CDS             complement(32231..33079)
                     /locus_tag="LP345_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1759951.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            33468..35234
                     /locus_tag="LP345_001156"
     CDS             33468..35234
                     /locus_tag="LP345_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBL1759952.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            35336..36595
                     /locus_tag="LP345_001157"
     CDS             35336..36595
                     /locus_tag="LP345_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1759953.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            36742..38043
                     /locus_tag="LP345_001158"
     CDS             36742..38043
                     /locus_tag="LP345_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1759954.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            38046..38897
                     /locus_tag="LP345_001159"
     CDS             38046..38897
                     /locus_tag="LP345_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1759955.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            38910..39725
                     /locus_tag="LP345_001160"
     CDS             38910..39725
                     /locus_tag="LP345_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBL1759956.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            39876..41042
                     /locus_tag="LP345_001161"
     CDS             39876..41042
                     /locus_tag="LP345_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1759957.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT        13972 a         7122 c         7991 g        12068 t
ORIGIN      
        1 aaaataagaa attgattgtc gttttctttt gcagaaattt aagtgcaggc aattatggta
       61 gttgtcgtaa ttgctgtcag ctcagtgttt atcactgatg gtgtgaaaga tttacggttg
      121 gagatgttca ataagattat tggtgcttaa ttatttttat tgtagtgctg atatgagaat
      181 gttataattg gggtataaaa catacaaata aatttgctga aaaatgaggt atcaaaatat
      241 ggaaaatgaa ttactggaaa acttaggaag acttcacaca actgaacttg gcgttattag
      301 aattaaaaag aacttatctt tgaatgtaga aaatgtaatt gaatggtgca aagaaaaaat
      361 tagcctttct aatgcggaaa tcacaagaaa aggaaaaaac tggtatataa cgattgataa
      421 ttgtattata acggtaaatg cgtacagtta taccgttatc actgctcaca aggtaaaatg
      481 ataaattttt ctataaagga attaaacgca tttgcagtta ttgggcagga agtagaactg
      541 actaattatc aaaaaaagaa tattcagatt agtacacagt tttggagaaa gtttaacagt
      601 agtttgaaaa aagcgtatct ttcacaatca ggaaattggg taaaatatgc ttttatggaa
      661 agaagaaatg gaaaacttta ttatttctgt tctattcccc aaagaaccat taccccagag
      721 ggctttctgt ataaagaaat accgtcttat aaatatttgg ttgtggagca tattggtgct
      781 atggataaaa tatatgaaac ttatggcaag atttatgaag aaattattcc tagtacatcg
      841 tatattccta taaaagatat tatcctacac tttgaaaaat acgattatcg ttttcattgg
      901 aatagtgata attcagttat tgaaatttgg atacctattc aagattagaa gcaattttat
      961 atccatacac acaaagcagt tagtcttagg attgactgct ttttctatac agatttttaa
     1021 tgacaggcaa ttatcaatta tggtagttgc cttttttgat tggaggaatt gaagaatgaa
     1081 tgataaaaac tttattgaag aactaagaca aaagcgtgag gaatacggag taacacaaac
     1141 aaggcttgct gttgcctgtg gtatcagccg tgaatattac aaccgcattg aaaaaggaaa
     1201 acagccattg aatgacgaat taagagaaat catagaaaaa cagattgagc gtttcaatcc
     1261 gcaagaacca ctattcttat tgattgatta ctttcgtgtc cgctttccta ctacggacgc
     1321 attggcgatt atccgtgatg tattacaact gaaatctaat tacatgcttt atgaagatta
     1381 tggaaaatac ggatatgaaa gcaaatatgt acttggcgac atcaatatca tgtgttccat
     1441 gcaggagcat ttaggtgttt tattggaact gaaaggcaaa ggctgtcggc aaatggaatg
     1501 ttatctgctg gcacaggaac gctcatggta tgacttcatg ctggattgta tgacggctgg
     1561 tggtgtgatg aaacggcttg atttggctat caatgataaa gcaggaatat tggatattcc
     1621 aaagttaaag gaaaaataca aggctggcga atgtatgtcc tacttccgta tgcagaaaga
     1681 ttacagcggt acagaaaaat gcggtagcga tttaccaaag aatacaggag aaaccttata
     1741 tctcggttca acaagtagcg aattatatat gtgtgcttat cagaaaaatt atgagcagta
     1801 tgtcaagaat ggcacagaaa ttgaagatac ggagattaag aaccgttttg aaatacgcat
     1861 gaagaacgaa cgagcctatt atgcggttgt agatttactg acctatcggg acgctgaacg
     1921 caccgctttt tctatcatca atcattatgt ccgctttgtt gacagagagg acgacaagcc
     1981 aaaaagtcaa tggataacaa atgatgattg ggcatggttt gtaggggaaa acagagagcc
     2041 gatacgctta accacaaagc cagagcctta cactttacaa aaagcgttgc attggctaca
     2101 aagacaagtc gcaccaacca taaaaatggt acaggcatta gacagagaaa atcgtacaac
     2161 gatactgaaa gatatgattg agcaggcaga actaaaagac aagcataaac atttattaca
     2221 attagagaaa tcaaccatag aagaacgtat agataccgct gttccacaag agaatgacgg
     2281 tattttttaa tgtaattgaa aaatttcaga tttagtcagc aaagagctgt tttcattccc
     2341 tatgtgaagt gaaagaagaa aaataaattt tttattaaat ctgcaacaaa atggctactt
     2401 gcgtacagat atggtgcgag aaaaggaaat ctaaactttt tttgaaaata ggtcattaaa
     2461 tcggggcttg ctgtccctat atgaagtgaa agaagaaaaa agttttgaaa aaatgacgga
     2521 aattcgtgat tagtggacag tcttctgtga aaagaggaaa aacatcatca ttttgtattc
     2581 aaacaggcat tagcagttga gtgttgatgt gaaaagatga aaatactttg ttctcaactt
     2641 aacaatttaa ggtttccgtt ccctatatgg tgcaaagaaa atatttcatt ctattgttgg
     2701 cagtaacggt atggtttggg tagttagggt gtgaaaagga aaatattctt ttttcatcat
     2761 caacttagca aaatgacatt ttctatccct atatggtgca tgaaaagaag ttaaaatttt
     2821 tccatttaaa cttagcaaat ggacgtttgc tgtacagata gtagtgaaaa aggagaaaat
     2881 caaccgttga ttgccaaaat gaaccgttcc atttgtacta ataatggaaa aagttttgga
     2941 ttttggttac gtttctcctc ttttccaacg cgatatatag gaaagacgat ttttttcttt
     3001 caatcgttct ttgacaactg aataaagcta ttcaatacgt ttgacagaca gctagccgtt
     3061 gaaacaaata cgccacgacc tttcccctgc aagagcgagc gaaaacctat ttgtgttctt
     3121 gtaaaagatt tgtcctcttt tatcgccatg acctgtactg tcagataatg atactcccgt
     3181 acagccacag cttgagcatt aagagcgtcg cacgcaatgg gtacggctac ataagaacta
     3241 tgcagaggtg gaactcctgt gggctatgac aaaagccgtt gaattgctta gaaagatttt
     3301 acagaaaggg ggtatgtgtt attgataatg ctgtaaaaac aattcaaaag aaaaatggca
     3361 agtgtggcat tggcaacaga ggaaagacaa agattgtagt aaaagagcat ttttccgaaa
     3421 agggcaaaac aatggaagaa cttctaactg atgtcatgct ggaaaaagca aagcagacaa
     3481 tcgcataaaa tcggtgcagt tgtaagaaat agattgaatg acaaaaagta cccgtgttat
     3541 actttacttg caagcaggta ttgtaaacac gggttagtta taaaggagga taactgacaa
     3601 tgaaacaaca gatttacaat actgcacttt atcttaggtt aagccgagat gatgaattac
     3661 agggcgaaag ttccagcatt accacacaga gaagtatgtt gcgtttatat gcaaaagaac
     3721 atcatttgaa tgtcattgat gaatatattg atgacggctg gtcgggaaca aattttgaca
     3781 gaccgagttt tcaaagaatg attgaggata tagaggcagg aaaaatcaac tgtgttgtaa
     3841 cgaaagacct ttcccgtctt ggcagaaatt atattatgac aggacaatat acagaattgt
     3901 atttccctag tcataatgtc cgctacatag cgattgatga cggtgtagac agcgaaaaag
     3961 gcgaaagtga gattgcacca tttaagaaca tcatcaatga atgggtggca agagatacaa
     4021 gccgtaaagt caaatcagca tttaagacaa agtttgcgga gggggctcat tacggtgctt
     4081 atgctccgtt aggatataag aaacaccctg acatcaaagg aaaactgttg gttgatgatg
     4141 aaacaaaatg gattattgaa aaaatctttt ccctagccta tcaaggttac ggaagtgcaa
     4201 aaatcacaaa gcagttaaga gcagaaaaag ttccgacagc gtcatggcta aattttacaa
     4261 gatacggtac ttttgcacat atctttgagg gaaaacccga aagtaagcgt tatgagtgga
     4321 cgattgctca tgtcaaggcg atattgaaaa gtgaggttta tatcggaaac agtgttcaca
     4381 atatgcagtc tacggtatcg ttcaagagca aaaagaaagt gcgtaagccc gaaagtgaat
     4441 ggtttcgagt agaaaacact cacgagccga ttattgacaa ggaagtgttc tatcgtgtgc
     4501 aggagcagat aaaatcaaga cgcagacaga caaaggaaaa ggcaacgccg atttttgcag
     4561 ggcttgtcaa gtgtgcggat tgtggttggt ctatgagatt tggaacgaat aagacaaata
     4621 aaacgcctta cagttattat gcttgcagtt actacgggca gtttggcaaa ggtaattgtt
     4681 ctatgcacta cattcgttat gatgtgctgt atcaagccgt attggaacgc ttgcagtatt
     4741 gggctaaggc agtacagcag gacgaagaaa aggtattgaa caagatacag aaagctggca
     4801 atgcagagag aatacgggaa aagaagaaaa aggcaagtac attgaagaaa gccgagaaca
     4861 gacaaaatga gattgaccgt ttatttgcga aaatgtatga agatagagcc tgtgagaaga
     4921 taacagagcg aaattttgtg atgttgtcca gcaagtacca aaaagaacag atagaactgg
     4981 aacagcagat aacaagccta agagaagaac taagtaaaat ggaacaggat atgataggtg
     5041 ctgaaaagtg gattgagtta atcaaggaat attccgtacc aaaggaactg acagcaccat
     5101 tattaaatgc catgatagaa aaaatcctca tacatgaagc aacaacgaat gaggataacg
     5161 aaagaataca ggaaattgag atatattacc gatttattgg aagagttgag taatcaacaa
     5221 gagtaatatt tttaactaag ggaaaccggc ggtgtctata cttgggtcag tcgcacattg
     5281 ggaaaacgat tcggttttgc cgcaatcttt ttccaatggt ttgagataac agttggctac
     5341 ttgaccatgc tgtatttctt aactggtgca ttatcctatg caacgggtat tggtgctata
     5401 caaaacaata aatatctgaa attggcaatc ctattgatta ttttctgggc tattttactc
     5461 tcacagttaa aaggaaccaa atacacttca ttgattgctc ggatcggttt tgtagctggt
     5521 atcttgttgc cagcattagt cttgtttggc ttagggatcc attatgtcgc ttcaggcgct
     5581 ccactacaaa cgatactgtc tatgaaaaca ttgattcctg atttttcgaa attgcctacg
     5641 ctggttgttt ttgtttcctt tattttagca tatatgggcg tagaaacatc tgccagtcat
     5701 gcaaatgaaa tggaaaaccc taaaaaggat tatccattag caatgtttgt attggttatt
     5761 ctggcaatca ttttagatac ttttggcgga ttgaccgtcg ctactacagt acctcaacat
     5821 ggtttgtctc ttaatacagg ggtgattcaa tcgttagaat tcctattaag acacattgat
     5881 ccaaatcttg catggattgc gaaaattctt gcgattcttg tttgtttagg tgtcatcgga
     5941 gaaattgctt cttgggtaac ctctccttca aaagcacttc acgtagcagc agaagaagga
     6001 ttacttcctg aatattttgc aaaagaaaac acacacggtg ttcctgctca tttgatgatc
     6061 gcaaatggga tcgttgcaac aatctgggca gccgtcttta cattaagcgg cggggggaat
     6121 aatctttcat ttcttgcagc gatgtcattg actgttgtaa tctacctgat gttgtacttt
     6181 atgtttttcg cgggctattt gaagctggtt tttaaagatg acagtcttga aagagcctat
     6241 caggttccag gcggaaaagt tgtaaaagta atcgttgctt gtttaggtct tttgacttca
     6301 ctttttgctt tttgtatctc atttgttcca cctgctagta tcgcagctgg acagcatggg
     6361 atttatgaaa cgattctgat tgtttcttat cttatcgtct tagttattcc atttacgatc
     6421 tacgcatgcc gtcataaatt ccagcatgca gaaaaataaa aaatgaaagc tggttattca
     6481 aatggaagta aaagaattag aacaattgat tggaaaaaat ttccactatt atcaaacagg
     6541 acaagtggcg gattacattc cagcattagc tgaagtggat cccaaacaat taggtatggc
     6601 gatttatgat ttggatacaa aacaactgat tgagggagga gacgccgatg tgcgctttgc
     6661 catcgaaagc atgtcaaaag ttcccgtatt gttattagca atcaaagaca acggaataga
     6721 aaaagtcttt caaacaatca acacggaacc aaccggtttt gccttcaatt ctatcatgaa
     6781 tatggaaatc aatcatcgca aacatccaat gaatcctttt gttaatgcag gagcgattgc
     6841 aacaacctcg ttgattgccg gtaaagatgc agatgaaaaa tttgagcgaa tcttgtcatt
     6901 tatgaaagag atctgtgatg atcctaatat cacattgaat gaagaaatct atcattctga
     6961 atcaagaaca ggtgatatca atcgctctct tgcttactat atgaaaggta atcaaatgat
     7021 cgaaggagac gtaccggaga tactcgatgc ttatttcaga caatgctccc tcaatgtcac
     7081 cgctacaggc atagcaaaat tagctgctgt gctggcaaat aaaggaattg ctccttggaa
     7141 tggcaaacaa atcattactg aagaaagtgc tacaatcgtc aaatcaatta tgacaactgc
     7201 tggtttgtat gatgaatcag gagagttttc cgtccatgtt ggtgtacctg caaaaagcgg
     7261 tgtaggcggc gggttgatgg cagctgtgcc aaatcgttac ggcataggtg tcttcagccc
     7321 ggcactagat ccatttggta acagcgcagc tggtatccaa ttgttgaaag atgtagtcaa
     7381 agaactagac gctgacatct ttgaataacc attcttgaaa gaggctgggg taaaagtcca
     7441 aacggctcaa agctacctac aatgaggctg aaattgtgag cttgtttgac ttttgtccca
     7501 gtttcttttt ttattggttt ttgaaagggc ttttctaaat aaaaaggaaa caaaaatacg
     7561 atttacagat atgattaaat aaaatcataa gaaaaactgg aggcgtgtat caggaatgct
     7621 ggaaaattac atcgagcgaa atatatttag aaaagtgtat ctgtgtgaac aattatttga
     7681 attccaagaa atagacatcg aacaaacagc tatttctcta agggtgacta caccaacgat
     7741 ccttcacgat ctagaaagtc tagccgagtg tctagaatat tgtataaaag aacaagtaag
     7801 agagaagcat aagtataaac tcgtattcaa acatggtatt gctctttctg agctcacaca
     7861 gtttctgtac ggtcaatctt attttttaaa gtttttaagt tattatttta atggtatatt
     7921 cacgagtaca gaactggctg atcttgaatt tatttctttg agtaaagtat atacaatcaa
     7981 aaaaatcgta ttggattttt ttaaagaaaa tgattatttg aaaaataaag aaatcattat
     8041 cccagaattt gactcgcgga acatcttgct agctttagta cgttatgtca attgggaagg
     8101 ctatgaaaat aaaaatccgt atgtagaaga agcttgtaac gagttgattg attatgtaga
     8161 gactcatttt tttaaaagaa gatattcgga agatgaaaag tcctttatca tacgagaaat
     8221 agagatcgca atcggaagaa aggcatttcc ccttggactg aaagaagaag ataagaaaag
     8281 cgcagaaacg aagccgttat ttcaattagt ctgtcaagga ttggaagagc aaaaaggaat
     8341 tctagactta caagaagaag atgtctatta tattttttct ttgttcaaca gtagaaatta
     8401 taccaatgag aacatggagc tgttaagaaa agatttcgaa gttgtttata aaaattttgt
     8461 tctcaatgac ctatcactga atgaattgat tttacagatt attagtatcg ctgaaatcga
     8521 cgatgcagaa aattttattt tcaagcaatc ctttttacaa tttgtccgta cgttgtgggc
     8581 agatggacaa gtatttttac cggaaaggat ctatcttcta tcagaaaaag aacaacttct
     8641 gtacggaaaa attgtagaaa tattggaaga gtggaaaaag aaaaatcaaa tccaactaag
     8701 atggaatgaa aatttcattc gaaaattcgt caaaagtctt tctttgatca acagtgaaca
     8761 agcggggaga caggaaatag aaatttttgt tgtttcagaa agttcagtca aacaattttt
     8821 ttatcgaacc caatttcatt tgtatgcgga agaaggcatc gctgaaataa atcctatttt
     8881 atttcgttca ttagaagaat tgcctgatga atgtctatgt gcgaaaaaaa gagtggtttt
     8941 gtgcgatgct gctagctatc aaaatggatt agaaactgaa aagacaaaga tctatccaat
     9001 ctcattaaaa ggtgcaaaca tccatttgta tcatattgct caggaacttc acctattaaa
     9061 aaaacatatt tcttgatgag accttaatta ggagaccttc tacaaagctt tttaattgtc
     9121 tgtagaaggt ttttatttga gtcctgattc gtgcgaagat ctacttatat aacaagcttt
     9181 ctctgaaatt tttttaaaat gctattgact tagagtcaac tctaagtagt agaatagata
     9241 aagtgtaaca aatctatttt cattaaaaga agatagtacg gaggagagaa tgtattatga
     9301 gtacagtatt acatgtattg gatgcaatca atagccccgc agatgtcaaa aaattatctg
     9361 ttgaggaaat gaaacagttg gcagaagaga tgcgccaaaa aatcttgcaa aaggacagcg
     9421 atgtaggtgg gcacgttggt ccgaatctag gtgtagtaga attaacgatt gcgtttcatt
     9481 atgtatttga ttcaccaaag gataaaatcg tttgggatgt ttcccatcag tcttatggtc
     9541 ataagctttt aactggtcga aaaaatggtt ttgaaaaagg acattaccgt gaagtgagcg
     9601 gatattccaa ccaacatgaa agtaaacatg actattttac agtggggcac acatctacat
     9661 ctatcagctt agcaacaggt ttagctaaag cgagagatct gaagaaagaa tcaggaaatg
     9721 tggtagcatt tatcggtgac ggctccctaa gtggtggctt agcttttgaa ggattgaaca
     9781 atggtggtgt tttacaatcc aatctaatcg tattagtaaa cgataatgag atgtctattg
     9841 atgagaatca tggcagttta tataaaaact tagctgagct tcgtcaaacc aacggtaaaa
     9901 gcagcaataa cctatttaaa gcaatgggat ttgattatcg ttacgtggat aatggaaacg
     9961 atctggaaac ggtgatccgt ttatttgaag aagtaaaaga tattgatcat ccgattgtac
    10021 ttcacgtcca tacggaaaaa ggtcgcggtt atcagccggc aatcgataat aaaatgaaat
    10081 atcattggca tgtaccattt gatctgtcca ccggggaggc aaagcaagta acttctggag
    10141 aaacatttaa tatgatcatc atggattatt tggataagaa aatgcaaaca agtacagctc
    10201 ctattgccgc agtcaatgca gcgataccag gcgcctttgg actgaaaaca ttccaagaaa
    10261 aacatccaga tcattatttt gacgtgggga tcgctgaaca gcactctatc actttcgctt
    10321 ctgctttggc ttctcaggga gtacgtccag tcgtcttcca atcaagtact ttcttgcaac
    10381 gggcatatga tcaattatca catgatttag cgatcaacga gaatccagtg attattttag
    10441 tcggtggcgg aacgatctca gctagtgacc gaacacacca aggaacattt gacattcctt
    10501 acttatcaag tatcccgaac atcaaatatc ttgctccagc aacaaaagag gatatgatct
    10561 ctatgctaga ttgggcgttc gaacaaacag cgcagcctgt agcaatccga attcctacac
    10621 atggtgtaga acatggtaca gctatcgcaa atgattatag tattccagcc tatcaaacag
    10681 taaataatgg aggaaaagta gcaattttag ctttaggcgg ttttcttgaa ttaggaaaag
    10741 aaacagtaaa agcttttaga aaaaaaggaa tcgaagcaac gttgatcaat ccaggaacga
    10801 tcacagaaaa tgacgtagaa acattagata aattaaaaga aacacacgaa ttagtcatca
    10861 cattagaaga tggtagtttg tcaggaggat ttggcgaaaa tatcagtcgt tattatggtg
    10921 attcttcaat gaacgtatta aattttggtg cagagaaaga attcacggat agcgttcctg
    10981 tagggcagct ttatgaacgt tatcatttaa caccaaaaca aatcgttgaa gatagtctgc
    11041 gtgtcttgaa tattcaataa ttcattatgc tcaccatcca gataattgtt tatactagta
    11101 tctggatggt tttttcatta taaaaagcaa aggggtggat gttatgtatc agcaagtaga
    11161 agaatatgtc aaaaagttcc aagaaaaata tcctagttat caatcagaaa aattaggttt
    11221 cttttcattt ggggatacag aaaaaatggc agacgagttg agcgaactag ttgtaaaaaa
    11281 gataaagact ggtacatcaa gtggttacga tctgtataaa caagagaatg agcctttacc
    11341 aaaagttggt caattagacg tggtcctgaa tggaaaaaat gaaccagttt gtatcatcaa
    11401 aaatataaat gtgaccatct tgccttttag tgaagtcacg aaagagcatg cttggaaaga
    11461 aggagaaggg gatcggacat tagcttattg gcggaaagtc catgctgagt tttttaaaca
    11521 tgcttataaa gaagcgttga acatagaatt tacagaagag aagctggtcg tatacgaaga
    11581 atttgaagta attttctttt agtaagaaag gtctgctgaa agaaatagct cattattgtc
    11641 tcctgaatag aaaagggtta catttttata tgaagctgta tttttatata acattactgg
    11701 aggagatatt gtggatacac tggaacaaat caaaggcgga gtcgtcgttt cttgtcaagc
    11761 tttggaaaac gagccgctac acagttcttt tattatgggg agaatggctt tggctgcaaa
    11821 agaaggcgga gcagttggta ttcgagcaaa tacgacagaa gatatcaatg aaatcaagcg
    11881 aatcgttgat ttaccggtaa tagggattat caaaagagat tacgatgggt cagaagtgtt
    11941 tattactgcg acagaaaaag aagtggaaga acttttggag acgcaagcag aaatcattgc
    12001 actggatgca acttctcgta aacgtccgac agaaaaaaca actgctgaac ttgtccaaat
    12061 gattcacgaa cacggtcggt tagctatggc agatatttcg acttttgagg aagcgcttca
    12121 agcgcaagaa gatggttttg atcttttgtc tacgacttta gcaggctata cagaatattc
    12181 acgaaagacg cagacacctg attttgattt attgaatcaa atcatagaac aagtcgatat
    12241 cccagtaatt atggaaggac atactgactc tcctgaacaa gtagagaaag catatgaatt
    12301 aggtgctttt tcagtcgtag ttggatctat tatcacccgt ccgcaattga tcactaaaag
    12361 atatgtcgaa gccgcaagta aagcaaataa ctaaaaaaca cgcacggcac agattcttga
    12421 caaaaaagaa aaattgatag atagtttaaa gcagattcta agaagatgaa aaaagcatta
    12481 cttttcattt tgtcttcaag atctgctttt taacgaattt tatagaaaga aggcgaaacc
    12541 atgtttgaac ggagtccttc agaattgaca gaacgtgaaa attacaagtt gctgattggt
    12601 tcagtcatcc ctagaccagt agcagtagta acgactaaat cagcaaaaga tatagtgaat
    12661 atcgcaccct tcagttactt caatatcgtc agttcgaatc gacccatctt atccttggcg
    12721 atccagagaa aacaagatgc agtaaaagac acagcaaaga atattcttga gacaagagaa
    12781 gctgttatcc atatccttga tgaggacaac gtagaagaag taaataaaac agcagccaat
    12841 ctgcctaatg aggaaagcga actgtacctg actgacttga ctttaactga ttcagtaatc
    12901 atttcagtac cagcattgac agaagcaaaa gttcgttttg aaacatcctt atatgaacat
    12961 gtcgagatac ggaataaaaa taaagtaaca gctgatttat ttttgctaga agtacagaaa
    13021 tatcatttaa atgaaacagt ctatgatgat aagacaggaa ggatcgatcc aagaaaattg
    13081 aatgctgtaa gccgtttggc aggaaatgat tatgcagcaa taggagaaat tttcacgatt
    13141 gcacgtcccg aataaaaagg agcactagtt atgttaaaaa taagctataa accatcgaca
    13201 gattcaaaag aaatgaaaaa agaatatgaa acagtgaatg attttctgca agggcagtac
    13261 ttagaagttc cgccattgca agaccatttt gtcgttacta ctgttacttt agatggtaag
    13321 gaaatagaaa tgccagatca aacgattagc ggattgttta attactttaa caaataaata
    13381 tttattccga aaagtgaaaa aacatataaa aaaacacata aaactaaaaa attatcaaag
    13441 aatcctggtg caactgaaag aatttgcaac gggattcttt caacttattt gttatttttt
    13501 tctaaaaaat attaaagatt gttaaatttc actatttcat ttcaaattcc attgcctaat
    13561 cattaggaaa agtctatcat gaactcgtaa atagaatata gtaataacct tgttaggtga
    13621 ggctcctata caaacatagg ctgttgccca gaaacgtcga aagtcgccaa tgggtaaaac
    13681 agaaactgtt ggattaaggc tttttccaat agctaagaat gttttcttta cgttgtatag
    13741 tgctaaaact cggacgatga gatgatgcta ggtcagaatt cttgttcgaa aaggtttctg
    13801 accttttctt tatatttttg tgactgactt atttgatgag acaaactcgc tcctcacctg
    13861 acaagtggat tgctgtgtga ggaggagatg cggtgaaaaa agatcgattg gtggattttg
    13921 ggtccttatt tgactttgtc catgatcggt cttttagaag tatacagtgc cagttcttat
    13981 cgtttattgc aagccgatga aaatacaaaa agtctattat tgcgtcaact aattttcata
    14041 tttttgagtt ggagcgtgat cttcttagct cgttcagtca aactacacta tttacttcac
    14101 cctaaaatag caggatacgg tttagcctta tcgattttct ttttagtatt agtaagaata
    14161 gggatattcg gtgtcactgt caacggcgca caacgttgga tctctctgtt tggcattcaa
    14221 ttccagcctt ctgaactggc aaatcttttt ttgatttttt atttaagctg gttttttcgt
    14281 gacggaaata gtagcccaaa agatctaaaa aaaccattcc tgattacagt aggtataact
    14341 tttctgattt tatttcagcc aaagattgct ggagcattga tgatcctttc gattgcgtgg
    14401 gtcatatttt gggcagcggc ggttccattt aaaaaaggga tctatctaat cgttactttt
    14461 tctgcattgc tgattggagc agcaggcggg gtattatatt taggaaataa aggttggctt
    14521 ccacagatgt ttaatcatgc ttatgaaagg atcgcgactt taagagattc ttttatcgat
    14581 agtcatggtg cgggctatca aatgacccat tcgttttatg cactatataa tggtggcata
    14641 tttgggcggg gattaggaaa tagtatcaca aaaaaagggt atcttccaga gacagaaaca
    14701 gattttattt tttcgattat tacagaagag cttgggctaa tcggtgcatt gtgtgtgctt
    14761 ttcttattgt tctcattatg catgagaatc ttttgtttaa gcagtcgctg taaaaatcag
    14821 caagctggat tgtttctttt aggattcgga actttgctat tcgttcagac gataatgaac
    14881 gtgggaagta tcgcggggct gatgccaatg actggtgtgc cattgccatt tgttagctac
    14941 ggaggaacaa gttatctgat cctttcttta ggaatcggaa tcacgttgaa tatttcttca
    15001 aagatacagg ccgaagagtt ggcgctctat cgacctgaaa aacaataaag agaaactgag
    15061 aaactctcag tttgaattat cataaagtac aatcttttat ttttcaagcg agaggttctt
    15121 ttagaaagag gaattcgcaa tgaaagtatc tcaaaaaatc atattatcta ttttgttact
    15181 gcttacatta gtagttggct atttttcgat tgagtttatc catggatttt cgtctgcaaa
    15241 acagagttca actgtgaaaa aggtagagcc gaaaagtatc cctaccacac taaatgtggc
    15301 tttgattggt tcagatgctc gttcgaaaga cgaaaacggt cgctcggatt cacttctggt
    15361 tgcacaatac aaccagaaaa cacaacaagc aaaactgatc tctatcatga gagattcata
    15421 tgtcgatatt ccaggttacg gaatgaataa gataaatgca gcttactctt atgggggagt
    15481 tgatttatta aatcaaacat taaaggaaaa tttcaaattt gaagctccct attatgcaag
    15541 tatcacattt caagatttta tcgattgcgt taatgaactg tttcctggtg gagtcaagat
    15601 cgatgcagaa aaatctctag atttagatgg cgtatatata aacaaaggag agcaagtgat
    15661 ggatggtaat actttactcc agtatgctcg atttcgggaa gacaaagaag gagacttcgg
    15721 gaggatcaga aggcagcagc aagtgatcaa agctatctct cagcagctga aagacgtaac
    15781 ttcaatattc aagctaccca aagcggttgg gaaattactt ggtagtatcc aaacgaacct
    15841 tccagaaagt gtgcttctgg attgtggtat ggatttcctc aaagacatat gttagaataa
    15901 acaggtataa atagtgaaat aaaggaatga caagcaagag aaggaggaaa aaatgaaaag
    15961 aagtgacaag cacggcaaaa atcgaacagg cgcttatatt gccggcgcag tgatcttaat
    16021 agcagctgcg ggtggcggtt atttttacta ccagcactat caagaaaccc aagcagtaga
    16081 agctggagaa aagacagttg agcaatttgt ccaagctttg aacaagggag attataacaa
    16141 agctgcagaa atgacatcaa aaaaggcggc aaataaaagt gcattatctg aaaaagagat
    16201 cttagataaa taccagaata tatacggtgc tgctgatgtc aaaggacttc agatatcgaa
    16261 tctaaaagta gataaaaaag acgattctac ttacagtttt tcatataaag caaagatgaa
    16321 tacctcatta ggtgaattga aagatctttc ttataaagga acattagaca gaaatgatgg
    16381 tcaaaccacg atcaactggc aacccaactt ggtttttcca gaaatggaag gaaatgacaa
    16441 agtaagcctg accacacaag aagcagcaag agggaatatt atagatcgaa atggtgaacc
    16501 attagcaaca acaggcaaac taaaacaatt aggagtcgtt ccaagtaaac ttggagatgg
    16561 aggcgaaaaa acagccaata tcaaagcgat tgcttcctcc ttcgacttaa cagaagatgc
    16621 tatcaatcag gcgatttcac aaagctgggt acaacccgat tactttgtcc cattgaaaat
    16681 cattgatgga gcaacgccag aacttccagc tggagctacc attcaagaag tagacggcag
    16741 atattatcct ttgggtgaag cagctgctca gctgattggt tacgtgggag atatcacagc
    16801 agaagatatt gataagaatc cagaattaag cagtaatgga aaaatcggtc gctcaggttt
    16861 ggagatggct tttgataagg atcttcgtgg gacaacaggt gggaaattaa gcattacaga
    16921 tgcagacggt gtagagaaaa aagttctgat cgaacatgaa gttcaaaatg gcaaagatat
    16981 caaattgaca atcgatgcga aggcacaaaa aacagctttt gacagtctag gaggaaaagc
    17041 tggatcaact gttgcgacaa cgccaaaaac cggtgatctt cttgcgcttg ctagctctcc
    17101 aagctatgat ccaaacaaaa tgacaaacgg gatctcacaa gaagattaca aagcttatga
    17161 agaaaatcct gaacatccat tcatcagccg atttgcgaca ggttatgctc ctggatctac
    17221 gtttaaaatg attacagcag caatcggtct cgacaacggc actatcgatc caaatgaagt
    17281 gttgacgatc aacgggctta aatggcaaaa agacagttct tggggatctt atcaagcaac
    17341 gcgtgtcagt agtgatgtat cacaagtaga cttaaaaact gctttgatct attccgataa
    17401 tatatatgcg gcacaagaaa cgttgaaaat gggtgagaaa aaatttcgta caggcttaga
    17461 taaattcatt tttggtgaag accttgattt gccaattagt atgaatccag cacaaatttc
    17521 taatgaagat agctttaact cagatatctt gctagctgat actggatatg gacagggcga
    17581 acttctaatt actcctatcc agcaagcagc aatgtattct gtttttacca acaatggcac
    17641 acttgtctat cctaaattga ttgcagataa agagacaaaa gataagaaga atgtcatcag
    17701 cgaaacagca gtacaaacga tcgtgccaga tctgagagaa gttgtgcaag atgtaaatgg
    17761 tacagcacat tctctttctg ctttagggat tccgttggca gcgaaaactg gtacagcgga
    17821 aatcaaagaa aaacaggatg taaaggggca agagaacagt ttcttgtttg ctttcaatct
    17881 tgataaccaa ggttatatga tggtcagcat gttggaaaat aaagaagatg atgattcagc
    17941 aaccaaacga gcatcggaac tattgcaata cctcaaccaa aattatcaat aaaaaattgc
    18001 tttttaagta cagtaaaagg actgtggcgt tatcgtcaca gtcctttttt caaataaacg
    18061 gttttcacga tgtctctttc acaacttctt tttgatttac tcacacttca taaacttttt
    18121 ttgtaaaata tttgagaaca agtggagaaa taagtgtact taataaaatc acgataacta
    18181 aaggtgaata gtactgtggt tcgatcaatt gactttgctg tccaatttgt aaaatgatca
    18241 aagccatttc tccacgcgaa atcataccag caccgaccat caatgaacta tgttgagaaa
    18301 aaccggcaat ctgagcacca aaataacctc caagcaattt ggtcaaaatc gctacaagcg
    18361 tcaatataga aataaagagt agttgttcac taaagtcaga aaaatcaact tctaatccta
    18421 cactgacaaa aaatactggt ataaatactg catatcctaa agcctctaca ttgtggtata
    18481 cttcttcttt aacctttgtc tgactgacag ctatcccagc aaaaaaagca ccaatgacag
    18541 agctaagccc aacaagatcc gctacgtaag acattcctaa acaaataact agcgatacga
    18601 tgataataga agaatttgcg tacacttttt ctgcaaatga aagtaggaaa ggcgcaatcc
    18661 atttgactaa taagaaaata aaaacaaaat aaattagctg ttcaatcaaa acaagcggta
    18721 aagaagcatt gctagaagct tcccccgtta gaaaagatag gctgaaactt agaactaaaa
    18781 cgactaaaat gtcatctacc acagaagcac ccaaaattgt tgatccttct tttgtattca
    18841 ctacgtttag ttcttttaat acttctactg aaatactgac agaagttgcc gcaagaataa
    18901 tcccaaagaa aatcgcttca tttcccgaaa cttggaatgc tttgcctgtc aaccagccaa
    18961 aaacaaccgg gaagatgatc ccaagcaaag caacgaacat accaggtcgg aaatattttt
    19021 tcaaaagaga taaatcactt tccagaccag ctaaaaacat taataagatc acaccaatct
    19081 ccgaaaagtc atggactaga atatcaggtt tgacccaatt caatccagct tggcctagca
    19141 aaacaccaac aagtaattgt ccaatcactg ctgggatacc taatctccgc gagatatgtg
    19201 agccaatcgt tgttgaaatc aatatcaggc ataaaatacc aataaattcc attctcatca
    19261 ttcctttgta taaaatatag cccgaactta gcataacata cattattgaa aaaataggaa
    19321 aatatactca caaaaaaacc aacaatccaa aagatttttt tggattgttg gtttttatac
    19381 ggtctatttt aataactaaa aatgattaac gtatagtcat ttttcttatt ctgatgaaat
    19441 tgataatctc ctggatgccc atgaaaatca aaataaagcc gaatatttgg aatagaagca
    19501 tcaaactttt gaatggattg aacaataaga cgaatccgcc aatcaacaac agaatactac
    19561 tataaacact ccaactttta gcttttgtat tcatgctgaa gaacaactgg aacaagctgt
    19621 tgatgataac agctaatcca agaagaatcg gcaggataga aacgattgca ggtgcaaaag
    19681 catagacgat cagagctaag atcaggaaaa aaagaccact gaacagaccg atactccaag
    19741 aacctgtttt ccttttaaaa cggtaagcct caaaaagatt caacaaccca agcaaaacaa
    19801 gataggcggt gatcagataa ccgataaaat gaaaaacagc agaagggttt agcacaatcg
    19861 caatcccaga aataatataa acagcagctc ttaataaggc gtatttttga atattttgtt
    19921 taatcgtctc aaacatataa gaaaacctcc tttgacttat tttaacgtga actagtcatt
    19981 ttaccaaatt aaatgttaca aaatgagcga aggagaagaa tatctctgga aaaatcaact
    20041 tctgaggatc ttttccattt ttttgccttt tgctagctca tcgatcattt tatctaaata
    20101 acgaatttct ttcatcaagt tatcctcgat gtcttctact cgtacaccac aaacaacacc
    20161 tgtaatcaag gaacgtgaag gattggggac aggggcttcc gcaaaaaatt gttcgaaagt
    20221 cacttgtttt tgtagttgat attctagttc tgtttgggaa taacccgtca gccaacaaat
    20281 gatttcatct acttcctctt ttatacgatc ttttctctcc gcttttgcta catacatagg
    20341 ataaacgctt gcaaaacttg tcgtaaaaat acgattttgc gccataatca gtcacctttc
    20401 tttttttcaa attatttact acttatagta tataagaaaa agagaagaaa aagcgattat
    20461 tcaaaaaaac aaaaaggatt gtgacaaaat tcttgtcacc atcctttttt ccgctctctg
    20521 actttttaca atcttcatag ctcaagtgcg catcagataa tcgaatgctc ctaaagctgc
    20581 agtagctcct gaacccattg aaacaatgat ttgtttgtat ggactatctg tacaatcacc
    20641 agctgcgaaa acgccgggga tattcgttgc gccatttttc tcggtcacta tttcatttct
    20701 tggattcatt tcgatcgttc catctagcca atccgtatta gggagtaagc cgactagaat
    20761 gaatactcct gaaacagcta gtgtatgcat ctccatcgta cggcgatcga tataggagag
    20821 agattctacc tgattcgtac cgctgatttc tttcgtcgct gcatgtttga taacagtgac
    20881 attcgcaaga gagactagtt tatcctgtaa gatttgatct gcttttaatt ctggtaagaa
    20941 ttctagaaca tatacatgtt ttgctaaccc agccaaatcg attgctgctt caacaccaga
    21001 attaccacca ccgataacag caatctcttt tcctttaaat aaagggccgt cacagtgtgg
    21061 gcaataagca attcctttat ttttaaactc tttttcgcct ggtacattga tagaacgcca
    21121 gtgcgcacct gtcgcgatga tggcggtttt tgctttaagt gatataccgt tagctaagcc
    21181 aatattaata aaatgttgct ctttatttaa ggaaacggcc tgttgattca tcataatgtc
    21241 gatagggtaa ctacgcacat gactttctac ttgctgcatc aattttggac cttctgtgta
    21301 agaggtacca atcatatttt caatccctag tgtttcaacg acttgtccgc cgaaagaatc
    21361 agcgacaagt cctgtacgga ttcctttacg tgctgcatag atagctgcac tactagctgc
    21421 tggtccaccg ccaatcacta atacatcata aggttctttt tcaaacaact cttcttcaat
    21481 caaagggcca gtgatttttt caacaatttg ttcgatcgtc atgcgtccgc tactaaattc
    21541 ttctccattt aaaaacacag ttggcactgc catgattttt ttatcatcga tttctttttg
    21601 gaacatccca ccttcaatca tcgtatgagt aatatttgga tttaatacag ctaatatatt
    21661 caatgcctgt acaacgtcgg ggcaattatg acaagtcaag ctaacataac tgtcaaaatg
    21721 caatgtttgt gttatttttt tgattttaag actcaaagat tcactgattt tcggtgcccg
    21781 tccactaatt tgtaacatag ccagtaaaaa agaggaaaat tcatgaccga gggggatacc
    21841 agcaaaaacg attccacttt ctttgccaac tggattgata gaaaaactag gtgtgcgcat
    21901 cgaatctctt ttttcccaag agattttagg agacatttct gctatttcct tcgtaaattc
    21961 agctagtttt tgactatttt cactattatc caaactaaca gaaaaaacaa taggagattc
    22021 aatcagtgct aaatattgtt cgagattttg tttagtttct ttgtctaaca tatccaccac
    22081 ctaaatcttt ccaacaagat caaaacttgg tttcaatgtt tcgccacttt ctttccattt
    22141 tgccggacaa acttcacctg ggtgggtacg tacatattga gcagcgcgaa tcttatcaat
    22201 cagtgcacta gcgtcacgac cgattccatc tgcattgatt tccatagctt gaacgattcc
    22261 gtctggatca ataataaatg ttcctcgctg agctaatcct tgctcttcat ccaaaacatc
    22321 aaaaatacga gaaatctgat gagacggatc accgatcatc acgtattcga ttttaccgat
    22381 agcatctgat gtatcatgcc atgctttgtg agtaaagtgg gtatcggtag agcaagaaaa
    22441 gacttcaaca cctaaagatt tcaatgtact gtattgttct tgtaagtctt ctaattcagt
    22501 aggacaaaca aaagtaaaat cagctggata gaagcaaaga atactccagt tccccataag
    22561 atctttttca ctgacttcta aaaattctcc ttgatgataa gcatgtgcat taaattcttc
    22621 gatttttttc ccaatcaatg acatagtaaa acctccaata ataattattt atttataatt
    22681 attgtaattt agttggagtt gcaaagtcaa tggatatttt gttatttaat aaagattact
    22741 caaaaacgaa ggttaattat aaaaatagaa gaggtcgcaa gaaaatgcta ctgctggaaa
    22801 tactcgggat aacgttgagt aacagtttcc tgttctttca gcatcatgtg taagtgcaat
    22861 cccgtttgaa atcgagcttc ttctggtttt ttatcaacta aagccttgag taaatcataa
    22921 tgttgttcca tgatcgtttc ccatggaagc ccctgaatgg tcactcgtaa ccagcggaaa
    22981 cgttctaaat gggtattatg gtcatctaac cagttccaaa cttcttttct tcctgcaatt
    23041 tcgaaacaag cttcatgaaa taaattatct gcacggaaaa aagcgcgttc gtcatttatt
    23101 ttgactgctt tttcttgttc ttctaaaatc gtttctagca ctattcgtgt ttgtgtgtcc
    23161 aatttggaac aacattcaat catgatttgc tcttccaact gttctcggac aaagcgagca
    23221 ttttctgcag aaacaagatt aattttggaa acatacgtac cactttgagg tatcgtatac
    23281 acgagttctt gctgacgtag ttgaatcaat gcttcgcgaa tgggagtccg gccgatagca
    23341 agatgttcct ccagtgcctt ttcagatatt ttccttccag gttctaagtc agcatagata
    23401 atttgtttac gaatcgcttg ataagcttgt gattgcaagc tgcttttcat ctttattcct
    23461 ccaaaatcat ttctatgaac gtagtataac agaagaggtc tgaaaaacaa tctggtatgt
    23521 cacattaact agtaaatttg tataaatagt aaaattttgg ttgacatagc gatttttatt
    23581 gcataaaatt cacttgaata caaaaactaa tatgttagtt taggagggga aaaatgattg
    23641 atttaaacaa ctggaggaac tttatccctg aattatctca aaaagaagta gaaatacctc
    23701 attttgaccg tgcatcatta agagaaaatg gacaaaaaaa tcctgtctgg atccatttcg
    23761 gtggcggaaa tctttatcga ggatttcatg cagaaatcgc tcaacgttta gcggatctag
    23821 gcgaattgtc cactggtgtc attgtttgtg aaacattcga tgaagaaata attgaaaggg
    23881 cttaccaaga ttttgatgat ttgattcttg aagtggtcat gccaagcagt ggagagttcg
    23941 tcaaacgtat attagctgcg acagctgaca gtctgtattg tcatccagat tgttctgaac
    24001 actttgataa gatgattcga cactttgaaa atcctagttt acaattagtt acttttgcta
    24061 ttactgaaaa aggttatcga ttgaaagata caaataataa atatatagga ccgattgcag
    24121 tcgatataaa aaatggtcca aagaagccat cacatacaat gagtattctt gctgtgctac
    24181 tttataaacg ttttttatct ggagcttggc cgattgcact tgtctctaca gataattttt
    24241 cacaaaacgg tagtcaatta cgtacttctt tgctaacgat cgcaaaagaa tggcaaaagg
    24301 aaggttatgt acaaaataca tttatccaat acttatcgaa tgaagaaatt gttgcgtttc
    24361 catggacgat gattgatcgt atcaccccga atccttcctt gtcagttagc aaaatgttgg
    24421 caaaagaggg cttttcaaat atgtcgattt tccaaaccgc aaaaggaaat aatattgctc
    24481 catttgtcaa tacagaggac atccattatt taatcatgga agatcatttt cccaatggac
    24541 gtccgaaatt cgaaaaagct ggggtattct tgactgatcg tgcaacggta gataaagcag
    24601 atacgatgaa ggtgacgact tgccttaatc ctttgcatac gtctttagct attatgggtt
    24661 gtttactggg gtataggagc atagctgagg agatgaaaga tccagattta tcgctgctag
    24721 tttctgaaat cgggtacaat gaaggcctcc cagttgtgga gtctccaggt atcattgatc
    24781 caaagatctt tctggaagaa gtaattactg tgcgcttttc taatccaaat attcctaata
    24841 tgcctcagcg aatcgccacg gatacctctc aaaaggtggc gattcgttat ggtgagacga
    24901 ttaaaaaata tatggaaata gaagttaaag acccgcagac acttgtattc ataccattga
    24961 ctctcgctgc ttggcttcga taccttattg gcattgatga tcaaggaaaa ccattcatcc
    25021 cgagtccaga cccactattg acagaccttc agcataagct ttccgatatt caactgggta
    25081 cgcaagatac atcacatatt catgagaaaa tggctcctat tttgtcaaat aaagaaattt
    25141 ttggtgtaga tctttaccaa gcagagcttg gcagaaaaat agaagaaatg ttcatcaaga
    25201 tggtagcagg accaaatgcc gtacgaaaaa cattacagga ttacttacaa gaacatggag
    25261 gaaatttatc atggaaatga cttttagatg gtacggatca caggaagaaa agattacctt
    25321 agatgaaatc agacagattc ctgcggtcaa agggattgta ggcacattga tggatatacc
    25381 agtaggagag gtatggccta gggagaggat caaagaacta aaagaagaaa ttgagtctcg
    25441 tgggttaaca ctaaaagtaa ttgaaagcgt caatgtgcat gatgccatta aaattggatt
    25501 accttcccgt gagcagtata tcgaaaacta taagcagaca atccgaaact tggcagaata
    25561 tggaatagaa gtcatctgct ataattttat gcctgtattt gactgggtga aatctgacct
    25621 tgactaccgc ttagaagacg gctcatccac gttagctttt atatctgatg atattccaga
    25681 tgatccaaga gaaatcgtcg cgcgcatcga acattccagc aatgaatttg gattgccggg
    25741 atgggaacct gagcgcttag ctcctatcaa atccttgctt gaagcctatg catcagtaga
    25801 cgaagaaaaa cttcgagaaa attttgccta ttttctccaa tcaatcatcc caacatgtga
    25861 agaggtaggg gtcaaaatgg ctgtacatcc agatgatccg ccatactcga tttttggatt
    25921 agctcgaatc gtaaagaatc gagaagattt agattggttg tgtcgcatag tagacagccc
    25981 ttataacgga atcactcttt gtacagggag tattgcagaa gatccagaaa atgatgtata
    26041 tgggatttta gcagaatttt gccaaagaga tcgaatccca tttgcacatg ttcgaaatat
    26101 taaattttta gctaatcgag atttctatga ggcaccacat aaatccgaat acggttcatt
    26161 agacatgtac cgcatactaa aaacaatgta tgacaacgga tttaacggat acatccgtcc
    26221 tgatcatgga agaatgatct ggaatgagac aggaagacca ggatacggct tatatgatcg
    26281 agcattaggt gctgtttatc taaatggatt atgggaagca atcgaaaaag gaaacaaaag
    26341 taaagataat tagtgaaaaa aactgtaatt ttattatgta aataagaagg atgttcaaat
    26401 tcttgataca taaatccgga ggttgttaat aagcattcgg atttatgtat cttatttggt
    26461 ctaggaagta acttgatttt cttttttcga ttgatccatg agtgcttctt cttttaattc
    26521 aaagatatat tctgagatcc tcataatcac ttttttccag tcttctggtg tgatgattcc
    26581 ttttaaaata tagatttttt tgatatgaga aggcaattgt ttcaaagggc agtcgctgat
    26641 aacgatgttg cagttctcca taaaatcatt ttgtattttg atcgattcat ttgaaaaaat
    26701 ttgttctatc ttaacgatca gatctttact gatataaaaa tcacgcgtat agttcacacc
    26761 aatcacaatt cgcggctgtt ttttgtagcg atcatacaaa tgtactaggt cttcaaccat
    26821 ccattgcaca ttttcctttt ctaaaataac tggtaacaag tgttgatttt gttctctgaa
    26881 atccatataa aattgttcaa tggcggtttg gacttctttc aatacgctat gttcttgata
    26941 aagcatgaaa gtaggaaggg gcgtatttgg ttgattgaag ttaagaaatc cattataaag
    27001 tttatttcgt gcgaatgcca atgagtaaag aatcttttct ttttcaggta taaacaaatc
    27061 aaatacagta caaagggact ccaccatttc tcttgaataa agaacatgag gaacgtttgc
    27121 tttttttaaa agtttgtatt gctccaagct tgtttcttcc gattcgattt tcgtgataga
    27181 aagtcgagct aaaatattca ctaagatgcg ttgttcgcga caaattggca gattaggtcg
    27241 caaaatatct acagagagat caataaaaaa gtcaatatat tcatactctg tgaattcttt
    27301 ttgtacgtct ttcacagaag ttgcaggaaa attctcttta catattttta atagaaaata
    27361 taatttatct atcataccgc tatttagtcg gtcaagtact tcttttttaa aaaaagtatt
    27421 catcataaaa gccactactt gcggatcttc atcataaaat tctgtagcag tacttgaaaa
    27481 gatgttccaa taaatatcta atgctgcata ttgaatttgt acctcttttc cagaaaaaga
    27541 ctttctgcca ttattagaaa aggagataga caaaccgtac tatgctaaaa atgcattaat
    27601 ctttttcatt ttcgtataca aataagaggc actatagttt gtttgctgac tgaaactgat
    27661 aatcgaattt gtctgacagc tgaacaaaga agtcaagatc tgataactga ctgattcgtt
    27721 gcagtatctt ccaaatagac gataatagca gtaagccgga tcaattcctt caaaattcaa
    27781 ctttaaaaaa ggtttttgct tatcaatatg cagttctgtt agattgagac gctcaaagtc
    27841 ttgttctaat tctttgatgt atagtaaaaa atttgattca gacatatgga aatgatctgc
    27901 taaatattgt gtagtaataa agaaacgatg ttcagatagg aaaagaaaaa tatctaattt
    27961 tgtattgctt tttttcttca agataaacgt tttaatcgct tcttgagttt gcatgaaaga
    28021 ggctcctttt tacttaaatt gttaaaactt gaaaatatta ctgttttttt cataaattta
    28081 gacaaaaaaa cagtaaacat ataggtagaa tctctactat cttatttctt gcatacaaaa
    28141 aaatcaagga gtgagagagt tatgagatat tcaaccatct taatatcaac atttgcagcc
    28201 ttaagcttat cgcttactat aaatcagaca gtccacacag aggagacaga aacagccaaa
    28261 tggacagaaa ccaagtgggc caacgtcaat cgaattacct ttcaggatga attttcatcc
    28321 ttcaattcag gagtcgcaaa attaagaaaa ggacaaacag cgaccatcaa agcaaaaatt
    28381 gactattcgg gagacttagc acctatacta caatcagctg ttacatttga gaatgttgat
    28441 cccactttgt cgattggcta tgacgagaac actttgacta tccaacacaa gcaagcgata
    28501 tttaccttca ccgttacatt aaatcaggac ttgttaaaac cagcgctttt tactgtcaag
    28561 gtatcagatg gactaccgaa cgatcatcat ttaacgccgt atagtcagcg gcagacaatt
    28621 gagcaagatt cagccatcga ctcaggagga gatcttgttg aagaaccaac agataaacca
    28681 gaaaatgaaa ataagccaga agtaccgcct acagaaaatc cagacggaga acagaaaccg
    28741 gaaatagaac ctggagaaga acccgataca gaaactcaac cagagccaga caataaatca
    28801 aaacctgaaa taacccctgg agaaaaacca gatgtaactc cagaaccaga tacggattct
    28861 ggaaaccaaa cagtaccgga aacaaatcca gacacagata atgaaactga aaatccagaa
    28921 aaaccagagg tagatccaga agaaaaacca gatgtgactc cagaaccaga tacggacgca
    28981 agagaccaag gaataccaga aaaaataaac aaaaaaacaa ttcaagagga tggaaaaaaa
    29041 gagagtaaaa aatcaaatct agcaattcta aaaataaatg aagagcagct gaataaaaaa
    29101 tcacgaatat ttgatagcgc ccaatcagct gaaaccttaa aaagtagcaa ggatacaacc
    29161 tttgctgtcc tgaaacgaaa aataaacagc taccaaaatc cggagagtca caaaacaaag
    29221 ttatactgtg gagcggaatc attctattaa gtatagcaac aatgctttct gcaaaaagat
    29281 ttaaacaaaa cagatctctc taacatttga ataatgtctg tgaacgcatt tttcaaataa
    29341 aaagaaatat ccagaaaatg accccaaaat accagattga aatctgatat ttggggtcgt
    29401 tcatacttta tctttcttca tatttatttt aagggatatc tgtttctttt ggaagatggt
    29461 tcgggatctt tttcactttc aatacatcta aaaagaaggt aaagatcgga atgccgacaa
    29521 tcaagcccca aacgccaaag aaccgttcgc taacaagtaa gaccacaaat gtataaaaaa
    29581 tcggcagttc tgttttgctg gacatcaact tcggattcag cacataagac tcaattagat
    29641 ggacaatcaa aatcgtaatc aggatataaa caacatctcg gatgcctcct tgggaataag
    29701 ctatgaaaga tagaggaata caagaaatga taacacctgc tactgggatc agacttaaaa
    29761 tgaaaatcat gatcgctaaa ctcagcagct gatgaaagcc aaatacagcc aaggcgattg
    29821 tagtgagcaa cgtatttaaa agagcgacaa caaattgagc ttctaatacc aaaccaaatg
    29881 tattgacaaa cttatcggca aaatagtaaa tatcttgaaa gaaccaagaa aattcacttt
    29941 ttaaaaacaa tcttgagaat acaattgttt ttttcttttc aatcataaaa aagaaactta
    30001 agatgaatga catagcaaac gccactgcca tttttcctat atcctgtaaa tagccaagcg
    30061 caatcgaagc gccattttga agctgttcaa aaaaatcgtt tcgctcaata taagtatgga
    30121 tatattgtaa aacaggatct gcatcttttg gctgatgctc gtaaaaatta ataacggact
    30181 ggatcatgtc aaatgtttga tgaataagca tcgggatata ctttgtgaat gccagataga
    30241 taaggtaaac gatcagtgta taaatcatga tagctaaaac acctgtaggg attcggacaa
    30301 atcgctgaat gatttgaaca agatgaatca tcaaataagt aaagataaat gtgagcaaaa
    30361 tggttgtaat catacttcta actaagaaaa gaacaaaaac gacaaataat aaaacagtga
    30421 gacggcgtat tttttcattc gccaaaaaac gctgataaac ggtcaaatcg acaacctcca
    30481 aataacaaaa aataaacacg ttattcatta tatgatggaa tatgaaaata agaaagagca
    30541 aaaagaaaaa ccgctaaatg acgttatctt atgagttggt tttcctcata aaatcgttca
    30601 tctagcagtt tcagcccttt ttctggtctt gatgaaaatt atctagcatt tttcgggtca
    30661 gatgttgcag tgtatccaat tcttcctgtt caagtggaag ataagacttg atcttttgtg
    30721 gaataccttc tgcttgtttt tgcaacgcag caccttgagc agtcagcgta acatttacga
    30781 ttctttcatc acccgtttca cgctgacgat taatataatt tttttctgct aactttttta
    30841 gtaagggagt cagcgtacca gaatccagac acaaatcatt tcctagctct ttcactgaag
    30901 tctttttctt ttcccataaa actaacatca caagatactg ggtataggta agattcagcg
    30961 gcttgaggag gggagtgtag tgtctaatga tttctttaga ggcggcatat aaaggaaaac
    31021 atacttgatt aactaaatat agatcttcca tttttccacc tccgctgttt tactatagtg
    31081 tatcatagcg gatttacaca aaaaagtcta ttcactaact gctttcagag taacttctat
    31141 atttccagct gtagcttttg aatacggaca cactttatgc gctgcctcta ataattcttg
    31201 cgtttcttcc agagaaagac cttcgataga tccttcaatc tctacaccta agacaaagct
    31261 cgtttcactt tctgaataaa gggaaacttg tgcactgaca gtagaagccc cagagatatt
    31321 ttttgctgtt tgatcaattc taatgcactg ttaaaacatg cactgaaacc agctgcaaac
    31381 aattgttcag ggttggttgc attttcgacg cgtttaccag gagctgcaat attcaattcg
    31441 aatgtacgat cgggattatg cacttctcca gagcgtccgc ctgtgttgat cattttcgta
    31501 gaatacattt ttttcataaa attaccacct ttaattatat tttatacaat tgaattttac
    31561 acaatataat tgtggaaagc aaagaaatgg attggcataa gataaataag agaaagcaca
    31621 tgaaacagac gcgctttctc gaatagcaaa catatacaaa aaatatcaga gacaaaaaat
    31681 aatctcatca taaacattac atatatttct caaaaagttg ttttctttct tcaaaaatta
    31741 cttcacgatg gacctgatga agcatccata aataaccaaa aggatctctg aacattgagt
    31801 tagtcacacc aaagtccatc atttctgtca tttcttgaat ctctacacag ccatttcgta
    31861 atgctttatt atgtgtgtcc tcgatatcag agacgatgat attgaaccag atcgtatttg
    31921 gatgttcagc agtaggagca gtcaaaccaa gagacgtgtt ttcatccagc atatggaatc
    31981 tcgtaccata caaggtaaaa atgacttcat tattgcctct agggtaatct gttgcctcaa
    32041 tcagttgtat ttcatcaaag attgtttgat acagttctag tgctttcaaa ctatcattta
    32101 atacaaaatc gatttccgtt cctttatgca taaagatctc ctctcctttt cagtcgaaca
    32161 gttactagat tcttttatta taccagctaa agaaaacgca ttcaaaaaaa tagcggattt
    32221 acttaccaac tcattcgatt ggatgataag taaatccgcg tcccattact tctgctacgc
    32281 tgctgacaat gacaaaggca cttggatcga tttcttctat caatggtttc attcgggaaa
    32341 attcatgatc agtcacaacg atcaataaaa cctcttttga ctttcgatta tacccgcctt
    32401 ttgcctctag cagggtaagg ccacgtccaa tctcagcact taagcgaagg cggatgtctt
    32461 ccaaataatg ttcactcatg accataacag atttctttcg attgatacct gtttcgatat
    32521 aagtcatgac aattgaagtg attgcaatag ataaaatagc ataaagaaac tcttctattc
    32581 caaaaataaa cagattaaga gaaacaacga atgcgtctgt aaaaaataag ccaatcgaag
    32641 tattcaagtg gaaatatttt ttaaaaatga ggggagggat cgtcgtaccg ccgctagaag
    32701 agttgttttt atataaaatc gcaactccta aagcaaaaat cgcacttcca aaaatgacag
    32761 acaacaaccg atctgaagta atcattgttt ctggaactat tgcaatgatt aaaggaaaaa
    32821 ccaagcttcc gaaaagtact ttaaaaaagg gttttttacc taaaaataga agagctagta
    32881 ccaacataac gatattcaac actaaaataa ctatagctcg gtcaaagcct aaagcagctt
    32941 ccagtaatat tcctagaccg ctgacacctc cagcagcaat atgatgaggc cctaaaaaca
    33001 tattgatagc gactcctaat atgaagaggg caaaaataat cttaatgtat gtccatataa
    33061 attgtctcgt ttctttcatt tattcacttc cttaattcat taataatact cttatcttat
    33121 tataacttac ttttcacctt aagttaactt taattaataa aaaaattagg ctagtctaaa
    33181 ttattatgtt tcattcttct agaatatact tctacgccaa aaactgttaa aaaactttta
    33241 ctttagaaaa ttggagaaat tgatcgctta agataaattc aggacactaa atagtacagg
    33301 aagtagacta aaacttttaa aagttttaag tctatctatt tggcaagttt aaaaaataaa
    33361 aattcggtat caaaaaactg ttaccgataa catttttgaa agcgttgtct tttgcttctc
    33421 tatcacttat agtgatgacg tcatattaaa acacaaggag gaaatcaatg gatacagctg
    33481 caatttatca tcgaccggaa agtgaatatg catttctata tacgaataca agatttcgta
    33541 ttcggcttcg tactaggaaa aatgatatca aaaaagtata tgtgctatgt ggagatccat
    33601 ataccataac aactgaaaaa tggtatcaaa aacaacgacc aatgaaaaaa tgtctaagta
    33661 ccaatgttca tgattattgg gaaattgaag tgacgagcga aacaagtcgc ttacagtatg
    33721 cgttccatgt tgttggggaa gataacacgg actgttttta cggtgatcaa ggaatttttc
    33781 cttatcgaga aaatgtgatt actgaaccaa atttttattt tcgaatacct tattttcatc
    33841 aaatcgatcg attcactatt ccagaatggg taaaagaaac agtatggtat caaatttttc
    33901 ccgaaagatt tgcaaacggg gacaaagcaa atgaccccga acacacttta ccttggggaa
    33961 gtaaagatcc agaccgagaa gactttttcg ggggagattt gcaaggtgtg atggatcatt
    34021 tggattactt gacggacctt ggcatcaatg gcatctattt ttgtcccata tttaaagcca
    34081 catccaatca taaatacgat acgattgatt attatgaggt ggatcccgct tttggcgata
    34141 aaaaactttt aaaaaacttg attgatgaag cacataaaag agggatacgt atcatgttcg
    34201 atgctgtatt caatcatatg ggtgtccatt caccacagtg gcaagacgtt ctcaaaaacg
    34261 gagaaaaatc gatctataaa gactggttcc acatccgttt tttcccagta gattcttatc
    34321 agatgactga cttaccagaa actgctgaaa atatcccata tgatactttt gcttttactc
    34381 cattcatgcc gaaactaaat acagcaaatc cagaagtgca aaaatatttg ctggatatcg
    34441 caacttattg gataaaagaa ttcgatattg atggatggcg tcttgatgtt gctaatgaag
    34501 tcgatcatca tttttggaaa aaattcagag aagcagttac agaaatcaaa ccagacatct
    34561 atatccttgg agagatttgg cattcctctc aagcttggct gcaaggggat gaattccatg
    34621 cagtgatgaa ttatgcattt acagattcga ttaaagatta ttttgcaaaa aagaaaatca
    34681 cagcttcaca aatggtcagt ggaatgaatc atcagcaaat gctttacaga gatcaggtga
    34741 acgaaggaac attcaactta ttagattctc atgatactgc caggatcttg accctttgcc
    34801 aaggtaacaa agaattgatg aagtctgtga tggcctttat gtttcttcaa aaagggtctc
    34861 cttgtatcta ttacgggaca gaaataggga tgactggtga agatgacccg gattgccgca
    34921 aatgtatgat atgggagaag gaggaacaag atctagagct attcggtttt ataaaagaac
    34981 ttgtttctct aaggaaacag ttgtctaaga ttatttctga aggttctact cagtggctaa
    35041 tagtaaatga tcgtgaagat aagctctatt tcacacggaa actagaggga cagatcatct
    35101 atgtttactt taatcagtca aaagaacctt gggtagtaga acaggaaaat gaggtgattc
    35161 ttagtcaaaa ttgtcagttg ttagaagacg ggaaagcaga gatacgacaa tacggatttt
    35221 tgatcatgtg ttgaaaactg ttaccggtaa caacaagaaa gcgtttgcaa atgaagattt
    35281 gtgcccatta taataagggt gtaacagcac gttgaataca aaggaggaaa tgaagatgaa
    35341 aaaaagaagt gtgaaacagt tgggtttagg gttaatctct ttaggaatct taggcggatt
    35401 agcggcttgt ggcaatggta actcttcagc agaaggggaa gccgatgaag gaaaaacgtt
    35461 aacagtttcc gttgattctg gatataaaga ttatataaac gaaataaaaa acactttcga
    35521 aaaagaaaac gatgtgaaaa tcaagctagt agaaaaggac atgttcgatc agttggaatc
    35581 attagcgtta gatgggcctg ctggaaaggg acctgacgtt atgatggcag catatgaccg
    35641 gatcggtgcg ttaggacagc aaggacatct ggcggaagta aaactgggaa atgaagcagc
    35701 ttacgatgaa acagacaaag cccaagtgac ttatgatgga aaaatctacg gagaacctgc
    35761 agtaatcgag acccttgttt tgtactataa caaagattta gtcgatacag caccatcaac
    35821 gtttaaagat ttggagaatc tatccaaaga cagtcgtttt gcttttgagt cagaagcagg
    35881 aaaaaataca ggatttttag ctaaatggac tgacttttat tattcctatg gtttaattgc
    35941 aggttacggt ggctatgtat ttggtgatga tggcacaaat ccttcagata tcggtttgaa
    36001 taatgcaggt gctgtagaag gaatctctta tgcaacagat tggttcaaaa atgtttggcc
    36061 aaagggaatg caagacataa aaagtgcagg agacttcgcc agccagcaat tcatgtccaa
    36121 taaaactgca gcaatcattg acggtccatg gcaagcgcaa acatacaaag aaaacaatat
    36181 caattatggt gtagccaaaa ttcctactct aaataatgga cagccttatc aaccgtttgg
    36241 cggaggaaaa ggatgggtag tcagcaatta tgctaaaaac aaagacctct ctcaaaaatg
    36301 gcttgattat gtaacgaatc aggaaaatca agaaaaattc tttgaaatgg taaatgaaat
    36361 ccctgcaaac caacaagcta gggaaacagc aaaggctaaa aacgatgaat taacaacagc
    36421 tgtgattgaa caatatgaaa cagctcaagc gatgccaaac atcccagaaa tgggcgaagt
    36481 ttggacaggt gcagaaaact tgatgttcga tgcagcatca ggttcaaaaa caccaaaaga
    36541 atccgcagat gaagcagtaa aaacaatcag tgaagccata gaacaaaaat actgattaaa
    36601 atgataaccg tccattttta taaaaaatgg aacaggtgct tcagataaaa gtggcaagag
    36661 cgagatggaa aattatcttg ctcttgttgc cattatctta aaagcagttt gcggtttagc
    36721 aagtttagag ggggcattca gatgcagcaa gataaaacaa gcaatatcaa cgaaaaaaaa
    36781 atcacgcttt gttcacttat tccagggatg gggcagtttg taaatggcca agcttttaaa
    36841 ggtatcgttt ttttcgccat attcgtccta ttcattggtc agatgcttct gggcggattt
    36901 catgcattgg taggattggt tactttggga agtataccaa tggaagatca ttcattattt
    36961 attttgattg aaggcacttt gcaattcatc attacaatca ttttcttgat tttttacggt
    37021 ttgaatcttt tagacgctta tcgagtagcg aagatgcgtc aagagggcaa aaaaatcaat
    37081 cggacgatga aggaagtcat acataatata ggtgatgaag gttttcctta tctattgaca
    37141 cttcccgctt atcttctcat gatttttacg atcattttcc cagtcctagt tacattgttc
    37201 actgcattta ctaattatga cttcaatcat attccaccag ccagtttaat tgattgggta
    37261 ggggctaaaa acttttttag tatcttcttt ttaagctcat atcgtaatac tttttttgca
    37321 gtcttttcgt ggaccgtgat ttggacttta tgtgcaacaa ctttgcaaat cacccttggt
    37381 attctcacag cggttgttgc tcaccagaaa tttattaaat tcaaacgtat tttcggtatc
    37441 attttcttat taccatgggc ggtcccagct tttattacta tcatgagttt ttcgaatata
    37501 ttcaacgata gcgtaggtgc catcaatact caagtgattc ctttcataaa ccagcttcct
    37561 tttgtagata tcagtgcaat ctcttggaaa acggacccga actggacgaa agtagcaatt
    37621 atcttagtgc agggctggtt aggatttccc tatatctatg tgatggttac aggaatctta
    37681 caatcgattt cagaagactt atatgaagca gcaaaaatcg acggagcaaa tgcatggcag
    37741 cgcttttcaa acatcacgct tcctgctgtc ttcctagtgg cagcgccaac atttattaca
    37801 cagtatacgg ggaatttcaa taatttctcc atgatctatc tgtttaacaa tggcggtccc
    37861 ggaagcgtag gcggaggagc tggttctact gatattctta tttcctggat ctataaactt
    37921 acgactggaa cttctccgca gtattctatg gcttcagcaa tcacgttgat tatctccgtc
    37981 atcgttatct gtgtgtcatt gctggtattt aaaaagacaa atgcgttcaa tatgggggat
    38041 taacaatgaa aaaatttcat tcgagtgctc gattccaaaa acgactttct cactttttta
    38101 cttacttttt tcttttaata ctgtcagtca ttatcatcta tccgcttttg atcacagcaa
    38161 gtactgcctt caagtcagga aatattgcag cttttagttt agatctttca agtgactgga
    38221 ctttaggaaa ctttactcgg ctattcagtg aaacacttta cgggacttgg tataaaaata
    38281 cattgatcat ttctgtccta acaatgatcg tacaagtgac tgtagtaact ttggcgggct
    38341 atacttatag tcgctatcgt tttatcggcc gcaaatcaag tttgatgttc tttttagtga
    38401 ttcagatggt accgactatg gcagcattga ctgcctttta tgtcatggct ttcttattag
    38461 aagcgctcga taagtactgg ttcttgacaa tgatctatat aggcggtgga attccaatga
    38521 atacttggct gatgaaagga tactttgaca ctgtaccaat agatttagat gaatctgcta
    38581 aacttgatgg ggcagggcat ttcaggattt ttttccagat tgtattaccg cttgtcaaac
    38641 cgatgctcgc cgttcaagca ttatgggctt ttatgggacc ttttggggat ttcatgttag
    38701 ctaagttcct gcttcgaaca cctgaaaatc agactgttgc tgtcggctta caaacattta
    38761 tttctgatgt gacaaaccaa agagtctctc tttttgctgc tggggcaatt ttgattgcac
    38821 taccgatttg tctattattc ttctttttac aaaagaactt tgttaccggc ctgacatctg
    38881 gcggaacaaa aggataggag cagagtatca tgcaaacatt tccgttaaac tatttttccg
    38941 cattacgtac gccaactcaa gtgtttgcgg gacgcaaact attatcatgg cctaaatttt
    39001 tcttgatatt tgtattttta gtttccttga tggtcatgcc tgtgactctt ttttatgcca
    39061 atcagatcca agcgattcca ttagaacaat ttctatccgt tcattcgctg atcgatgaac
    39121 aaggaaccca aaaattttct gaacttgaat tatctgaaac tgggttacaa gcatcgcaac
    39181 aaacgatagc tgtgacccct gaaattttgg taggtgtgtc tttatctgag aaacaacaat
    39241 ccgatcatgg aacttttatt gattttgaga aggaacaatg ggtgatccaa caaaaggata
    39301 aatctggtat acgccgctat acgatgaatt atagcccatc tttccaacca gattctgtac
    39361 gtacgcccga agatttccaa cgatttttag aaagagaatt ttatgccagt aatcgtccaa
    39421 caatcatttt atcttatagt ttaagtcttg gtcttgtcct atttgtcatg acgagtctca
    39481 ttttattcgg ggcttccttt ttcttgtgga tgacaagaaa aagccaactt tcatccattc
    39541 atacattcaa agagagtgca aatttgatgc tgaatgttat gggaataggt tccatggcag
    39601 cagcagttgt agggtttatc cactttgact ttatcttgat gctaagtgtc caaacaacga
    39661 taactgtctt gctgctttta tgggtttttg tcaaaacaag attcaaagat aagcgtgtcg
    39721 aatgacaagt ttaagcgatt tatgcgacaa tgaatgtgaa aaaaatgaaa aataaagtag
    39781 tttttgaaaa atttctgaaa aaattaaact tcttagttga ttcttttctt ttttagtatt
    39841 aacgtaatag ggtagttttt ttaaggagga aaatcatgtt agagaaaact ttatacaatc
    39901 aattattttc acgttctttc tcgctccctg tcgaagtaaa ttattgggac ggtacaacga
    39961 aacaatacgg agatacggac actcctcccc aaatcaaaat caatatccat gaagaaatcc
    40021 caatgaaaga gattacaagt aacgcatctt tggcactagg agaagcctat atggatcatc
    40081 gaatcgagat cgagggaagt atccaagcat tgatcaacga tgcttatcag caagcaaaca
    40141 gctttttacg aggaaaagat tatctaaaat ggctgccaaa gaaagaaaaa catacgaaac
    40201 aaaaaaacaa agaagatatc catgcgcatt atgacttagg taacgacttt tataaacttt
    40261 ggctagatcc aactttgact tattcttgtg cttatttcaa tacacctgaa gatacgttgg
    40321 aacaagcaca aatcaataaa gtccatcata tcttagacaa actctttatc aaagaaggcg
    40381 aaacgttgct tgatatcggt tgtggctggg gaacattgat gttcactgct accaaagagt
    40441 ataatgtcaa ggcaactggg atcacactaa gtgaagaaca atacgatttg attaccaaaa
    40501 gaataaaaga agaacattta gaagataaat gccgtgtatt attaatggat taccgcgaac
    40561 taaaaggcga aacgtttgat catatcacaa gtgtaggtat gttcgaacat gtaggttctg
    40621 aaaatcttga aggttatttc aaagtggtaa aagatttatt gaaaccaaaa ggaacagctt
    40681 tgatccatgg aatcagccga caacaaggcg gtgcgacaaa tgcttggatc aataaatata
    40741 ttttccctgg cggttatgtc cctggtgtta ctgaattagt tgataatatt acaaaaaacg
    40801 atttgcaact gattgatttg gaaagcttac gtcgtgacta ccaattgaca ttagaacatt
    40861 ggacaaagaa ttttcatcaa gtccaagatc aagtcacgaa agaaatgggt gattccttct
    40921 atcgaatgtg ggatctatat ttacaagctt gtgcagcttc atttgaatca agtaatatcg
    40981 atgtgattca atatttgctt gttcaacctg gaaacaatga catcccaatg catcgtgcat
    41041 aattgaggca aaagtactgt ttaaagacta tttaaaaaga agctaagttt tatgatgctc
    41101 cagaagtgaa cttttttgtc taacttctag gattgtctct aaagcttagt ttc
//
LOCUS       DAFEIE010000020        39146 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFEIE010000020
VERSION     DAFEIE010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.020"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..1350
                     /locus_tag="LP345_001162"
     CDS             <1..1350
                     /locus_tag="LP345_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1759958.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="LP345_001163"
     CDS             1484..2827
                     /locus_tag="LP345_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1759959.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4390
                     /locus_tag="LP345_001164"
     CDS             2939..4390
                     /locus_tag="LP345_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBL1759960.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4739..5371
                     /locus_tag="LP345_001165"
     CDS             4739..5371
                     /locus_tag="LP345_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBL1759961.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5959..7398
                     /locus_tag="LP345_001166"
     CDS             5959..7398
                     /locus_tag="LP345_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1759962.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7693..7911
                     /locus_tag="LP345_001167"
                     /pseudo
     CDS             7693..7911
                     /locus_tag="LP345_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8160..8375
                     /locus_tag="LP345_001168"
     CDS             8160..8375
                     /locus_tag="LP345_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759963.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8592..8848)
                     /locus_tag="LP345_001169"
                     /pseudo
     CDS             complement(8592..8848)
                     /locus_tag="LP345_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9035..9946)
                     /locus_tag="LP345_001170"
     CDS             complement(9035..9946)
                     /locus_tag="LP345_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1759964.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9965..10969)
                     /locus_tag="LP345_001171"
     CDS             complement(9965..10969)
                     /locus_tag="LP345_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL1759965.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10966..13089)
                     /locus_tag="LP345_001172"
     CDS             complement(10966..13089)
                     /locus_tag="LP345_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1759966.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13094..15541)
                     /locus_tag="LP345_001173"
     CDS             complement(13094..15541)
                     /locus_tag="LP345_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1759967.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15528..15917)
                     /locus_tag="LP345_001174"
     CDS             complement(15528..15917)
                     /locus_tag="LP345_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1759968.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15977..16480)
                     /locus_tag="LP345_001175"
     CDS             complement(15977..16480)
                     /locus_tag="LP345_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1759969.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16493..16717)
                     /locus_tag="LP345_001176"
     CDS             complement(16493..16717)
                     /locus_tag="LP345_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759970.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(16821..18731)
                     /gene="ltrA"
                     /locus_tag="LP345_001177"
     CDS             complement(16821..18731)
                     /gene="ltrA"
                     /locus_tag="LP345_001177"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1759971.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(19477..19614)
                     /locus_tag="LP345_001178"
     CDS             complement(19477..19614)
                     /locus_tag="LP345_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBL1759972.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(19611..20795)
                     /locus_tag="LP345_001179"
     CDS             complement(19611..20795)
                     /locus_tag="LP345_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1759973.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(21054..21344)
                     /locus_tag="LP345_001180"
     CDS             complement(21054..21344)
                     /locus_tag="LP345_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759974.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(21334..22476)
                     /gene="dcm"
                     /locus_tag="LP345_001181"
                     /pseudo
     CDS             complement(21334..22476)
                     /gene="dcm"
                     /locus_tag="LP345_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(22552..22716)
                     /locus_tag="LP345_001182"
     CDS             complement(22552..22716)
                     /locus_tag="LP345_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759975.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(22709..23383)
                     /locus_tag="LP345_001183"
     CDS             complement(22709..23383)
                     /locus_tag="LP345_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL1759976.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(23461..24801)
                     /locus_tag="LP345_001184"
     CDS             complement(23461..24801)
                     /locus_tag="LP345_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL1759977.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(24884..25219)
                     /locus_tag="LP345_001185"
     CDS             complement(24884..25219)
                     /locus_tag="LP345_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBL1759978.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(25229..25603)
                     /locus_tag="LP345_001186"
     CDS             complement(25229..25603)
                     /locus_tag="LP345_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1759979.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(25616..25930)
                     /locus_tag="LP345_001187"
     CDS             complement(25616..25930)
                     /locus_tag="LP345_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1759980.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(26043..29270)
                     /gene="fss3"
                     /locus_tag="LP345_001188"
     CDS             complement(26043..29270)
                     /gene="fss3"
                     /locus_tag="LP345_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL1759981.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     DDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(29684..30850)
                     /locus_tag="LP345_001189"
     CDS             complement(29684..30850)
                     /locus_tag="LP345_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1759982.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            30875..31201
                     /locus_tag="LP345_001190"
     CDS             30875..31201
                     /locus_tag="LP345_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759983.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDAGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            31354..32406
                     /locus_tag="LP345_001191"
     CDS             31354..32406
                     /locus_tag="LP345_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1759984.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            32482..32700
                     /locus_tag="LP345_001192"
     CDS             32482..32700
                     /locus_tag="LP345_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759985.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            32687..35260
                     /locus_tag="LP345_001193"
     CDS             32687..35260
                     /locus_tag="LP345_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759986.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKF
                     DSNHETVIIDSEIRENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSC
                     N"
     gene            35251..35448
                     /locus_tag="LP345_001194"
     CDS             35251..35448
                     /locus_tag="LP345_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759987.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            35452..36063
                     /gene="mobC"
                     /locus_tag="LP345_001195"
     CDS             35452..36063
                     /gene="mobC"
                     /locus_tag="LP345_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBL1759988.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            36048..37439
                     /locus_tag="LP345_001196"
     CDS             36048..37439
                     /locus_tag="LP345_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL1759989.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            37655..37969
                     /locus_tag="LP345_001197"
     CDS             37655..37969
                     /locus_tag="LP345_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759990.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            37962..38456
                     /locus_tag="LP345_001198"
     CDS             37962..38456
                     /locus_tag="LP345_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759991.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            38524..38838
                     /locus_tag="LP345_001199"
     CDS             38524..38838
                     /locus_tag="LP345_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1759992.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            38937..>39146
                     /locus_tag="LP345_001200"
     CDS             38937..>39146
                     /locus_tag="LP345_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1759993.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT        12473 a         7258 c         6980 g        12435 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag
     3181 tagtacgact tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgacttc
     3241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtaccgaatc
     3301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa aaccaaacca
     3361 tatagaatct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa ctttttcgac
     3421 accacagcaa atagaatcaa cagaatcttt ccaatcacaa ccaatactat ctggtaatga
     3481 agaaattcat tttgacaaaa atgaatctgt agaaaatttt attatgaaaa ttggtgagtc
     3541 tgcgagaaaa attggtcaga aatatgattt atatgcttct gttatgattg cacaagcgat
     3601 cttagaatct gccagtggtc aaagccagtt agctcaggca ccgaattaca atttatttgg
     3661 gataaaagga acttataatg gaaactttgt cattatggta acaaacgaag atttgggtaa
     3721 tggaacgctt tatacgaccc aatcaaaatt tagagtgtat gaaaactatg aggaaagctt
     3781 tgaagattat gccaaattat taactaaggg aattagtgga aataaagatt tttatgcagg
     3841 agcattaaaa gctaatagta aaacatatcg agaagcaact aaattcctta caggacggta
     3901 tgcaacagat acacaatact atttgaagct aaatgaatta attaaaacct acgatttaac
     3961 caactatgat aaagaagtta aaggtccaca aatgagtaag actggatacc aagtgcctat
     4021 tcataattat tcaataacca gtttgtttgg aaatcgtgga aatgaatttc accgaggact
     4081 tgatatggca gctacacagg gtgagccgat tcatgcagtt aaagctggta aggttgttaa
     4141 agcagagttt cactactctt ggggaaatta cgtggtgata caacacgaag atggatcaac
     4201 cgcgttatat gctcaccagc aacaatacct agtaaaaact ggagataatg ttttgcaagg
     4261 acaaataatt ggctatgtag gaagtactgg gaatagtact ggcccacacc ttcatttgga
     4321 aatttgcaaa gatagtagtc tttctcagag catgttagtt gatccgaaaa ccttattatt
     4381 cggagactaa aaaaggtaat caatctgaca aagtaacaag aaaatggttg gattcttaga
     4441 cctttgatca ggatattgag actggaattg atatctcgat tacgatgggt ttgacaaata
     4501 aaacaagtcc attatcgaat atcgagtgta ttattgccgt ctttatgctc atattttgag
     4561 caggtttcac tagatgaaaa caatttatct atcttgagga tttcgtgtac gtatcgttca
     4621 gtcttgtatt gtaaattagt cataaaatca gactaagaaa aattggaaat atttttttct
     4681 gatttattaa aagttaattg aaattatatg gtacttcttt cttgggaggg taggtgcagt
     4741 gaaggaaaga tatggtcacc ttactgttgt tgaggagatt actcataatg gatataaaaa
     4801 atatcgttgc ctatgtgact gtgggaatga aacgattgta tatcgatcaa acttactatc
     4861 aggtagaacc aaaagttgtg gatgtggaaa ttataaaaat aggcataaat ataaaaattt
     4921 gacaaataaa acttttggta agttagttgc aatcaagcca actaaactgc gaagtgaagg
     4981 aactgttgtt tgggaatgtc aatgtctgtg tgggagaaaa aagttagtat cggcaaagcg
     5041 acttctaaaa ggtgatgtaa aaagctgtgg atgtttgaaa tcaaaaaagc atcacattga
     5101 aaataaaaaa ttcggattac ttactgcaaa gtatcctttg gacaataact gttcatggaa
     5161 aacaaaatgg gtttgtcatt gtgagtgtgg cagtatgtgt gagataagtt atagtaactt
     5221 attttttgga catactcaaa gttgtggatg tttaaaaagg caagaaacaa ggacatgtgt
     5281 tgaagggaca gtaatagagt gtctaacgtc aaaattaccg aaaaataata caagtggtgt
     5341 taagggagtt tatcgttcta aagagaaata gattgcgtat ataactttaa aaaaaaagag
     5401 gtactattta ggatcgtatg attctattaa gagtgcagct caagctagaa aagatgctga
     5461 aaataaattg tttcaacctt tgattgacaa atatcgaggt aatcattaat tattgtggat
     5521 aataattaac agtgatatat aaacatctat aatatattat tcatactatt gatatttagt
     5581 ataatcctat ggaattgaat atcatagcaa tgtatttgaa aagcaaattg gaaaacaaat
     5641 aggtgcaaca ccataaatat gaaaaaattg ggaaaaagta gaatggaaat ttgcttacgt
     5701 ctcacgagat agctcacact attaatctga agaacaatga agtcgacttt tagaaattgc
     5761 tagaagaaag taaagcgaat tatcactagt tactatagag taagttcaaa taaagcatct
     5821 ccaacttaca tggttacatg aggatatcaa atcgaaatta ctcaagcttc ctatggctag
     5881 agtcgcgaga agttgttggg cagtagacat aggttatatt gttcttagct acacgatcat
     5941 tagaaaggaa atcctattat gtatagttat caagaagatg caaaagtcca aaaaaatcgc
     6001 tggtggattt tgattgctat atctatgttt accttcatgt ccacattgga tggcagtatt
     6061 gtcaatattg cactacctac catctcagat gatatgggca taccaatgaa tcaagcggaa
     6121 tgggtagtgt ccgtttatct gatgattgtc tgttcttgtt tgttgctgtt tggtaaaatt
     6181 ggcgatagcc gtgggaaaat caaagtattt cggattggta cgctgatctt tgtcttggga
     6241 tcgctgttgt gtgggttcaa tcattcgcta ggtattttat tgttcgcacg ggtggtacaa
     6301 gccattggtg ctagtatgac tatggctaca aatgccggaa tcatcacgga agtctttccc
     6361 atacatgaac gtggtcgggc attgggagca ataggtgcgt ttgtttcatt aggctcgatt
     6421 gctggaccag gtcttggcgg cttgattttg tcccaatttt cttgggcgta cattttttgg
     6481 atcaatgtac cggtgggaat cgtaacgatg ttgattgctg aaaaattctt accaaaagat
     6541 atcaccatga gcggccatac aatcgatgga gggggctttg ctgccattgc ggctacgatt
     6601 atcagctttt ttggagcaat ctttttgggg caagaaagtg gctttttcca tccagtcccc
     6661 cttgtactgt tcgtaatttc agtgattgcc tttgtcagct ttttaaaagt tgaaaagaaa
     6721 gcagcctctc cattgatttc tttcggtatt tttaagaaca agatttttac catgagcttg
     6781 attacagcct tgttgatttt ttcttccaac ttctttgtca atgtagtgat tcctttttat
     6841 ctgcaaaatg ctcgcgggtt gagtcctagc tatgctgggc tgttgatgat ggtctttcct
     6901 ttgatgatgg tcgtcggggc gcctttaagc ggctacctga ccgaccgggt tggcccggag
     6961 attttggtat tagtaggctt gggcttattg tcggtaaccc aggtcatgta tatgtttttg
     7021 tcagtggact ctcctttgtg gctatacatt gtcgctactg ccatcatggg tgccggcaat
     7081 gccttgttcc agtcccccaa taatacgatg gttatgagct cggtcactat cgaaaacttg
     7141 ggactggcag gctcgatgaa ttcctttgcc cgaaatttgg ggatggtcag cgggatttcg
     7201 ctttctacga cggtcttata tcaagcgatg tctgctaaga tgggccagca agtaactaac
     7261 tatatcgcaa atcggccgga tgtcttttta tatggaatga agattacctt tttaggcagc
     7321 tttgttttgt gttttgttgc ctttttcctg actatctggc gtatcaaaaa acaaggaggt
     7381 attcagaaaa atgtctgaaa aaaccactgt tgaagaattt ttggaggcct gcgtatgggt
     7441 gagtgggatt tccatggatg atggaagatg aagtgaactt ctaaaagccg aaaaactcaa
     7501 gtattatctt caaaatacta gtgctcaatg agatgcttga tttgatcaca agaagactgc
     7561 gaaagccgct ggcaaccgca agctaggtat cccaccgatg gactacgttt tagaggctac
     7621 tggttatgaa tacggagcca acgctctcat ctgcataaga atacatcacc cagattatgt
     7681 aaagattttc gatacttctg tcaaaaaatc attaagatag ataaatgatt tccgtctagt
     7741 caaattggtt cagaatgtag acacacagat ggtaagaagt cactcacaat tcgagaatgg
     7801 acttgtccta tttgccgtat acatcataat cgaaacgtca acgatagtat caatattttg
     7861 accaagggct atgaatacaa gcattgcctt agaaaacatc aagaacctta ggaacaacgg
     7921 ggatagcttg gttaataaga gataccgctg tttaggcttg caagtatact cttttatcaa
     7981 gaattccgtg gctttagtca tgagaggctt aatactatga aaattttctt tagcattttt
     8041 gatttaggtt ccttttctaa ttataataag atgaccacta cagtaaccta ctgaaatata
     8101 taaacagcca ctgtagtacc attttcaaag tagtctatga gaggagaatc ttcattctta
     8161 tgaacgctgg aattgcggat atgaatttaa taaaaaaaac ccttaatgat tttacttcca
     8221 attcaatatc aaaaggtact ggtatcaatt taagcacaat aaaaaagctg aaaagtggtg
     8281 aaagatcagt ggaaaagctg aatcttttag atgctataaa aataacggaa tttgctatga
     8341 aaaatggaaa agctgagatt gaaatatgga gataattatc gtctagtgaa ttacttgcca
     8401 cttagctgaa tttaacgatc cttggtgctt gaagggggag attcttggga atagagcata
     8461 cttgcaagcc tatgtcttta ctaacaacga tatctcttat taaccaagct atccccgtag
     8521 ttctaaggct tttactttta tctaagcaat aatcgtattc aaaggaaatt tttgaccctt
     8581 agaaagtctc attttatcag acgtgagctt aggcattgct gaattttgtt aattcggttt
     8641 taggttgtgc tttgagcata atatgaaagt attctttatc acgatttcat tcatctaagg
     8701 taatgtgatg tgattctgaa attctttcaa aggcagtttt tgcataagct gacattacat
     8761 catcaatgac atgtttacaa tgtttcacta ctaaaataag ggggtaacca agaagaaaaa
     8821 ctgaatgatt atttgtatct aattccatgg tatatcaacc atttcctata tagactgatt
     8881 atgacatgga ttaaaataaa aaggcactat gtcttaattg tcggttttcg agttaccgaa
     8941 tggcattcat cacccaccta tagaggatgg gcgacttctg cctgaaataa gttacactac
     9001 ttataacttc taataaaatt agattgagtc attattattt aacatcaacg attttccagt
     9061 ttccattttt ttgtaatact aatttgtact gaaagtagct agtggttttt gatacattat
     9121 caaggtattt tatctttgta ctcactagaa aattttttcc gttttgtaga taaactggat
     9181 tctctaactc cgaaaacttt aagtcaatat tgattggtcg catcgcacca ttttcaacat
     9241 aatactccaa ttctttttca gaagctgatg gataaagttt aaaaaatgtt tctaaaaaat
     9301 cggtgatttc ttccgttgtt ttggcatcaa tttctgaatc gttttctact tgttttgctt
     9361 catattttgc cttgtctggc tttccaatca ttgttggcaa actagttact aaatgattcc
     9421 tgttttcatc ttcaaagatt gtcactcgat atgcagaaga aattgattgc gtcttttttc
     9481 cctctgtaat atgttgctcc actaaaaatg aaacgacaaa ttcttccgag tgtttttcaa
     9541 catctagaat ttttacagat tgaacttcgg aactcgtggg aatatctgct cgaaccatat
     9601 cttggattaa agcgagaccg ttttctgtaa ggtactgttc gagattactc attctctttt
     9661 caattgcttc tttgttattt ttccatgaaa aatattcttt cgcaaaatcc tctgtaaaac
     9721 tttcaacgcc agaagtattc actaccttct cttttataac cactttttca tgagttgtat
     9781 gttgatcaat ggcggtgaaa tttttataaa cgccaaaagc aagactacaa gacaataaaa
     9841 gccaaagggc aagcaccatt tttcgatgct tacccacgga tacaactcgt tcttttttct
     9901 tttttgggct cttttccttt tgattccgtt caatttttat cttcattctt tttcctcttt
     9961 tctcttattt gtatcggcca gctccgataa gatgctgccg ccaatagttt tccgttagat
    10021 tcgtccaccc cactggatct cctgcatgaa acatgcgatt ctcccctgcg taaatgccca
    10081 catgggtcac ataagtaccg gcatcatagg ttgaatgaaa gaaaactaaa tcacctggtt
    10141 tggcatcttt tagatcaata tgagtcatgg catcatattg atcctgagcc acccgaggaa
    10201 gtttcaggtc aactttggca taacaccatt gggtcaagcc actacaatca aaccccgttt
    10261 ctggacttga gccaccaaac acataggccg ttccttcata cttaaatgcc tcatcaaaaa
    10321 tttcttggac tattttgtca tcaaactgag ttgtagttag gtattgcttc actaataaac
    10381 agtaaaacat attgccataa ttataccgcc acccaccatt ttccttaatc gcgattgggt
    10441 tggggtaatc gactttttga ccacctgatt tttcctttga aaaagattca gctaaagcaa
    10501 aactatgctt cttcccgttt ttcccgacat gatctagata cccgccacca tagttatagg
    10561 cctgaataat actatcttga tcacacccta gttctttgga acgcttaacc aaagacgcaa
    10621 aatagagaca gccttgtttg atggatgcct cggtacttaa tgaattaggt ggtaatccgg
    10681 ctgactcaga actttgcata acgtcttcca ttgtgccacc agattccact tgaataatcg
    10741 ccaaaagaat tggaatatac tctgttatat ccgattcttt ggcatacttt tccaccattg
    10801 cacggtgttt caatacttct tctgagacac tagttccgcc aggagaagtg ccagaactac
    10861 catttccctc actgtcttca ccaaacaaca aacccacaca catcaaaata cccataaaag
    10921 agatggtcag aaaagttaat gaaataacac ccactttctt caagttcatt ttttctcacc
    10981 tgaccttgat tttggacgat ggttcattct tttttgtact ttttgattgg tctgctttgg
    11041 cagagtggac ctctgtttca cttgttggaa agaatttttc ttacttgctg attggctttt
    11101 cccttttgaa atgatttctt gactagttag ttttcgtttg atttcgggat tcagatttgc
    11161 tctcacaatc cgctttggtg cttctttttt cagcatcata tctttctgag gttgagctgc
    11221 tttatctatt ggaatattcg cccttctttt tccctgacga tttgttgctt cactcagtat
    11281 cttgcgtttt tcgtccattt tcgcatttct tcgttgtcgt tgtttttctc gcaaatccac
    11341 tcgatccgct ttttcttgga acagtccgcg cttgaattct tctggtgctt ttttcgactt
    11401 ttcgattcct ttatggagat tgtatttcaa attcgttggc gtattcctta cctgatcctt
    11461 tacttgttta gtcttatctt tcaccaaagc ttgggtatcc aaaactttgc cgatttttct
    11521 cccagccaaa ttcattcggg attgtttctt attatttgaa actggattct ccttagttaa
    11581 gtcagatagt atttcgtgat cgttcggtaa tcgtgaattc tttcgtagag aagaaccgga
    11641 tggcttaaat ttggattttg attgttcctt tgccaactta tttccgactg ctgcaccacc
    11701 accaaaagcc aaagctcgtc ccacatttcg attgagttgc cgcaattttc gattcattaa
    11761 catttgcggt tttcgcatga cgcgtcttcc cattgactgg ctatcattac tctggaggtt
    11821 gaacatactc ataatgtcgc ccaatttgaa atagataccg gcaaaggtca caatttgcag
    11881 aaaagcaacc atgaaaaatg gataggttgc cgaaatattg aaaaacatcg tggagatgct
    11941 aaatgcagtc gtaatcacca aagtaacacc cgctcgcatc ataatcgtat tgaataaacg
    12001 aataatcgcc ttctttccta aactttcata agtcggcaac atggacaata agaaactaat
    12061 tggcagaaac atcgcaaaga taatgaagag aatttgcgag aacaacataa tccctgttag
    12121 aagaaaaaca aagaaggaaa tgccaatatt gaacaatacc aaaaagacca cggtccctaa
    12181 acggttcatg gtcttggtaa tactgagatt cgcattgtca ttgtcttcaa tctctgcctt
    12241 gaccgcttct tcccgatctt tgcctttgtt ttcatctgga ctcacagata gaatcttgtt
    12301 gacccggtct tcaccaattt cttctatgtt ggaatcatca aattgcagta gtaaccaagg
    12361 ttgttggact tgaatcgaaa acaaactatc ccgaatcaaa tccacactat cttttccttg
    12421 gctttctgaa ttgggtacaa cgatctcggt tccaagggta agggccgctt cactaacatc
    12481 tgagctaaag tcattgattt ttgtgatata ggtaggcgca taagcaatga acgaacccga
    12541 tagtagaaaa atcatcacaa aattaatcac ggctcgaact gctttcgtgg tttctcgttt
    12601 taataatccg gtatacgcca catacacccc cagagctaaa atcatcaata atagaaaccc
    12661 aaaataaaat ccggaggtct ggagtccatt ttcagtaata ccagccaatg tttggatatt
    12721 ctttccaata ctttcagccg tatccgaaat gaaatctaat ttgtaagcct cttgaaccac
    12781 ataacccgtg gcgttcgaca aatacaaact caccgtccaa atgaaattag taatggcata
    12841 aagaccatac atcacgcttt tccctaagcc atcaccccaa ttccaaggca accaatccca
    12901 agagctatcc acaaagaaat ctagttgata gttgttcagt gaatatttgg aatatagatt
    12961 tcctgcttca actgtatcat caactagccc tgtcgcctcg gctaccgtac caactaaact
    13021 caatagaact atcagagtga gtatgctaat aaaaacgatt cccacaatcc gaaaaagttt
    13081 ctttttcatc ccctcactcc attctctctt gaacaggtgg acgggtatca aaggcatgga
    13141 agagttcttc aaagactgga tgtacctgaa ccacgcctac ccgaccatac aaatcctgca
    13201 tcaagcattg gccattttcc aaatctcgta ggcgtttttg attgctttca tcttctcgat
    13261 ccaagccaaa gaattccaag gttttcttga tttcatgaat atcggtactg cgaaacgcaa
    13321 acttcaaccc gatattattc ttcaagcgtt catccagtaa atcatcacta ttttgcgtga
    13381 caaagtaaac cccggcattc atagcccgcc cagcacgaac gagcttattc gataatgttt
    13441 tcccttgcgc tacttgaaga aaactccacg cctcatctaa gtctacaatt ttgaagattt
    13501 ctcgattact atggataaag tccaaggcaa aagtggaaat gacgattagc atggaaacac
    13561 taagcaattc catggtggta tattcttcaa aagtggtttc tgcatctggt aaaaccaaat
    13621 ccgctacttg aatgatattt aactgcctat ctaaactaat cgactgggta atcgaaccat
    13681 ctgagaaaag caaatgggca aaatcataat cggtaaagga ctcgatgtga tccgcgatat
    13741 tttccgcaac tggtgagcct tcttttcgaa gctcattaat tacttgtaat aatccccgtt
    13801 gattgctttg ggtaaccgtc cgaatggcct tacgcaacac tggaaacttc tccccatctc
    13861 gactagaaat tcctgttaaa aaggtcagaa tatcaattgc tagactttca gaatccttct
    13921 ttttctccat aatcacataa ggatcaagta atccttgatt ttttggctta ctagttaagt
    13981 tgagaatatt gatttcatcc gcaatttctg gcaaggtttc tttccagcca ccccgttccc
    14041 cttttggatc gacaatcaca gcttgtccac caaaaaggac ggcgtaataa actaagagat
    14101 tgttactaaa ggactttccg ccaccgagtg aaccgaggaa tgccgctgct agcgcattgg
    14161 taactgaacc cttgacccct tgtgaggcca atgccggttt caggtaaaca ttgcgccccg
    14221 tatctacgtt ataaccaaag taaatgcctt ccaactcccc taacatctga gtggcgccaa
    14281 aaccaagtcc ggcgagaaaa tcagacgtaa catactggat ataatcattc atgtatcgct
    14341 tactagaagg taagaattct tcatgtagcc ccatcatatc gccaaaaggc cggactagtt
    14401 ttacattggt atcatcataa aaatctagca cttcatcaca ccggcgcttt agttcatcta
    14461 ctgattcggc acttactcga accacatagc tcagtttgta catggattct ttggactgat
    14521 ccaaggtagt ttccaattca tctacggaat ccaatgcatc taagacattg gaatttgttt
    14581 cattgtcaga ttgataggca tggttgtcca agtcttttaa ttcctttttc ttattgcgaa
    14641 cggtagcaag tgcctttttg ttcgtcacaa tctccacatt catactagtg tcaattggga
    14701 atgtaaattg ttgttgctgg taatagaaaa gttctgagga gggaaactcc atttccccca
    14761 caattgtatt aattgttaag tacgctacat atgattcatg attctcatgt tccatgcata
    14821 agtaccgggg cttttcttca atcaaacaac gactgggacg taataagtcg taacgtttca
    14881 ccaaagtttc cgacttcagc tttttctttg gtagctgaaa ttcatattct tcaaatggtg
    14941 tacccttttc gccatagata tgttcaatca aatacatcag atcactcggt gtgactcgtc
    15001 tgactttaaa tcttcgagcc aatttacttt ccattagttt ttcaagcttg gtatatcggc
    15061 gaatttcttc attggataag gaaacaaaat cgcccatcaa atgatgattc actccataga
    15121 caaattcttg aaagccggag aagaaagatt tcttgagatt ctttagattg acctcttcat
    15181 ctgtcgcaat cagtttgaag ccaataaaaa agcgataatc aatctgacta tcgccaatca
    15241 tggatactaa tgcctctgtc tgtaaatcaa ttcgttgttt cgctacttct gttaatcgcc
    15301 cggtaatttc cttttttgat cgttcttgcg tggcacgaat actactttct gtggcaattt
    15361 gtaaggcatg aatcttgcct tcacgatttt gcgcaatcaa ttgacgaaag ttatcgtgga
    15421 cttgatattt ctgttcaggt gacaaaaagg agtaattgta aggtattaac tcatagtagg
    15481 caaaacattc tccctcttga ttaaagacaa gattattttc aatatactta atcgggtaca
    15541 tagttcacac tccttaccag agtaatgggt tcgtcccatc gtttcttctg ttctttgact
    15601 ttctttcctg cgaaagtgac cttaaatcgt aagtgatagc taataaaaga tcgtaaaaat
    15661 cccaatggtt tcttaccgtc aaacgttttt tgcgacatga accaagtaac tgccaccggt
    15721 atacctaagt attttaaaaa ggccccctct atcatagata gtggaggcac atgggcaaat
    15781 acgatgacaa acagcaagga taaaacaaac caagccatct ggttaaaagt cacaggaaaa
    15841 ggcagttgaa agtcattaat tgcataaatg accttttcaa ctgcccaaat actggtgtag
    15901 ctttttattt tcttcatcaa atcattcctt taaaaagaag gatagtttag aaatcaacta
    15961 cccttcaata attttgttaa tatggatact caaaaacacc tcgactcgtt accaaataat
    16021 tgcctccaat ctccaagtct ctaccacacg catcaaaatc aatatacgtc ttcaagtgtt
    16081 ctggtacttc tccaaaatca ccagcttcta caatcaagaa atatgctaca tcactcatat
    16141 catcgcaatc tggataatag ataatatcat ccacatgctc taccatctcc tcaaaagaat
    16201 tgaagaaagc atgttgaatc tcagaagcaa cttcaccaac tggcgttcct tcaagttcct
    16261 ccgctaagcc acacaaccga ttaatttcct caattggcgt atactcatca atctcaaagg
    16321 gaagttcata atcatgaatt gcatattcct cgtattcgtc atttaaccca attcgttctt
    16381 tcacttcatc aaaatcgaca ggtggggtaa accacgcccc caccaattca ccttcgttat
    16441 atttcccgag gttcgcaata taaacacgca tctgttccat cgtgcttccc ccttacgcac
    16501 cgacaattcg gttaaacaaa ctgagtaaga catccttcac cccagaagca ttaaagacca
    16561 atccgaccgc aatcaaagca atcaccaaaa agccaatcag tttggaaaac tcccgcttaa
    16621 atcctaaaaa caaaccaatg accacaattg ccagtaagac taaggattgg gcattggtta
    16681 aaaaccattg atatatggat aggtaagttc ctgatattat aaatatctca aacttttccc
    16741 cccattcaca cggagcgtgc gactttcacc gcactccgcg ttccatcgtg tttatattga
    16801 aaagtattta tgtagtagac ctatatcaag tttaattctt gattgccagc taatactcta
    16861 tatttattta gtcttatgag ctggacttta tttagcttca atagagctat atatttttgt
    16921 attgtttctt ctgttttagc gtgtattaga cggtgtaccg cctcttttac caaaataaga
    16981 tttttataat cgtcatttcc accagctcca gttggtacaa tatgatgaca atgtatttca
    17041 ttagcttgtt gaaattcttc cagagttata gcacattttc catgttgagc agaaaatagc
    17101 gaaattcgat tgtctgcgta ttctattgtg cgattttcca aagataattt cattaactgg
    17161 tacatcagta atttatcaac acttagattg gtgtggataa attttcttcc ctctagagtg
    17221 tagcaattcg ctaaatacac ctttgccatt ggttttctgt gttggatata tccaacaggg
    17281 aaaataggtt cgccctcgcc agcaacatac cgaagcattt tagatttacc atatcttgtt
    17341 gcctcctttg tcgtaagttg tctgcctgtt tttctcaatc tgcccctttt gtttgtacct
    17401 aatctgttag tgaagatagc cattacagct ctattcagtt tcatacaatc cagatttaca
    17461 ttcgttgcaa tctgataata attttgcata cctaatacca ttgaattata aagtcttgtt
    17521 tcttctaatt ccgttttccc ttttgaggga gaagcaattt tctttgcctg tgataccagc
    17581 ttgtcttttt ggtttttgaa ttgtttatca cttatatgtg atttaacaac taacttcttt
    17641 cttctcggta tcattttaat cttgaaacca agaaagtcgg agtatctttt tctaacattt
    17701 acaattcttg ttttttcttg tgatacttcc aattttaatc gttgttcaat ccattgagtg
    17761 attgctattt tggctttttc agcactttcc ttgtagcggc agaaaactct aaaatcatct
    17821 gcataacgaa ccatatacat ttcctttaac tttgttttct tcatttcttt gtaagcgttg
    17881 cttttacatg ggctaccgct tttattgata tgaaccacat agttttttgt aacaggattt
    17941 tcctgccatt ggctttctac ccaatggtct aactcattaa gaacaatgtt tgctagtagt
    18001 ggggatatta ttcccccttg cggagttcct ttctctggat atgttattgt accgttagtc
    18061 attttgattg gagcttttaa tatccttttt aaaatgaata tcaagtgctt gtcccgtatt
    18121 cccatagccc atatctgttt tatcagcttg gaatggttca cgttgtcaaa gaaaccctta
    18181 atatcaaatt caatcacata atgtagctgg ctgatttgta ggcggttata ggttgctttt
    18241 attgcatttt caactgacct attaggtcta aaaccatagc tgttttcact aaatttagct
    18301 tcgcagattg gttctaatac ttgttttata cattgttgta taagcctgtc ccacatacaa
    18361 ggaataccta gaggtctggt tttaccattt ggttttggta tttcttttcg cctcactggc
    18421 ttaggtcgat acccatgtgg actgcctgca acaatgtatc ttactttttt gacaactgtt
    18481 tctgctggca atttgccaat atctttaatt attgtaccgt ctgttcctgc tgttttactg
    18541 cctgcatttg ctttgatatt tcgatatgcc agtaatatat tttctctcga taggataata
    18601 tccataagat gagtgaaaat atctccattc ttacttttgg catataaatc atcaaaggtg
    18661 ttttgcattt cgtaatattc agcgtgtctt aaatcttcta cacacaatgt ttcattttta
    18721 tttttaggca taaggcttca ctcctttact tgaaattgag tgagcttttt tatcttactc
    18781 gtaatcctta ttgaaacaac ataatacttt tctaatatat acacgacttg agggcattcc
    18841 tccattctca ttacaagaat ttcttaggtt cgccctctgc ttttcagcat tagttcaact
    18901 gcttattgtt cttcgtcagt ttattctctt gatgagaacc caataccttt cctcgttccg
    18961 ataatcttat ctatacatat atatccttag gtcactagct ataagcctgc tggcttgata
    19021 ccgcctgtaa cgttatatgg catttcataa cctatattct tactttgcca caccagctac
    19081 gatttctcgt acctttgcat ttctacaaag ttcaaattta gacccgtaca ttcgctgttt
    19141 cgtcagttcc ttatagaaca ttctaaccat agatatttta tagacccccg acctgttgga
    19201 tacgctaccc acctctggat agttttcgat agaagatata tgttcatcaa ctattacggt
    19261 atctttcagc cgtctttacc gagcttcaaa cattctgagt ttcctcatac aatgcttgtc
    19321 ggaggctcag ggcaggcgtt tcagagcgtt acttcatcat tccacctgtc agattatcag
    19381 ttctcctaat aaccaaactt tttcgttctt ttattagtgc cttagctttt cactaaggaa
    19441 cgagtcgcac ataaattttg tccgaaattc atcttgtcac tttcctttct tttccattgc
    19501 tcgatccgct gctgcacttg cattcatcaa gcacatcaca gtaacaccaa gcatactgcc
    19561 accaaatacc aaaaaaatat cttttacaat tcccatgacg attcctcttt tcatataatc
    19621 aaattttcaa ttgccatact ttgttgctcc aaaatctttt tatgtcggtc tgataagcgt
    19681 gcattctgta ccatatcctg gatataggtt gtccgattca atcgatccaa ctccttagcc
    19741 attttccacg taggggcgac ttgtcggcct agccaattca aggttcgttc aatggtatac
    19801 ggttttggct cggaagttaa ttgaatctct ttccgattcc gtccaataaa acgcccccat
    19861 tgttcattca agggccagtt ggttcgcctt ttaccttcta ctttatccgc aaatcgcaag
    19921 taacgattga taatggaaaa cgtggtgctc tcaatgctac gaccttttaa caaatcttga
    19981 atcgcatgaa aagcacggtc atttttcagt cgaatctcaa aacgattttt cgtctcagtt
    20041 tggtctaatg gaatccctaa cttgatatat tgttcatagt ctttttcata caaacagaaa
    20101 taaacctcac tcttgagact gccgatatat aaggtattgc ccatgccgtc cttttcatca
    20161 gcctttaaaa gttccccgga acgataactt ttaaaggtac gaaacaagga gatacattct
    20221 tccttctgac attttttcgt tagctcaggt atatccaata gccccactcg atcattgatt
    20281 gccaagtcca agcgtttcat cacgccaccg gcctttagac aatcctcgaa aaagtcgtac
    20341 cagctacgct tttgagcgag taaaaaagtt tcaaattgtc ggcaacctcg cccctttaat
    20401 tctaaaagca cacctttatc ttcttcatga gacaacatca ccacaatatc acccatgaca
    20461 tactgttctt gataggagta aaaggcataa tcttcatgga gcatatactc aaatttcaaa
    20521 tggagaattt cttgaataat ttttcgtgca tccgttgtgg gaaagcgaat ccttacatag
    20581 tcaaacagta acgtcaaagg caaatcggga ttaaagcttt ccagttggtc aaaaattttc
    20641 ctcatggttt ttatagatgc ggttacgcca ccattttcta tctgatttaa gtacggccga
    20701 ctaagtccac aagccgtagc caatttattt tgtgaaacgc cgtattcgtt gcgtcggtct
    20761 tttaatagcc gataatctaa attccgttgt gccaagttct cacctccaaa ttcaaggtgt
    20821 taactttttc aaatgagtta acacctatac aaattactta ctatctttga tacaacaagc
    20881 attcttaatg gttgcttact tattttttgt gtttttgtac ccccctgtta gatacggggg
    20941 tgagacatca tggtcggcta acgccgtcca tgaacaggca cagcaccacg gaggatttct
    21001 gcttcgcgaa tcctccgcgg tcagcgccta acagtcagtt gtgttggttt aggttactca
    21061 tctgtaatac catttacttc caactctgct ttcatttcta acaagtattg acgaatatct
    21121 ggttcttttg cttggtccgc aatccgctca aattctgcaa ttacttgatt tatttcaatt
    21181 cgagcatccg tctcctcatt cattaaatat ggatcgccag cgactttgac accattcttg
    21241 cgaatatcaa attttaaccg tcgcaattgt tcttctaatt ctgggtctga ctgaatcttt
    21301 ccaatcaccc aataaatttc tccaatcaac tcatcataaa ccatgtacat ccaactcttt
    21361 taatcttctg gcaatatcaa aaatgaccgg aactgttaca gagtttccgg cttgcttata
    21421 caactgacta tctgaattga cttgagaatc tcgatcaaaa gcccaatcgg gaaagccctg
    21481 aagtcgccaa cactctctag gtgttagctt ccgaatttga tactgatccg tgacgatcgc
    21541 ttgttggtct cctgttagta aggtatgaac actctgtttt cccagacgac ctcggcgact
    21601 tgtggaatta ggaaaagcca gattcacact gtcttctggc ttcacctctt gatattctgt
    21661 ttcatttttt cgaatcatga tttttgtacc accttgtttc gttgacaagg tgggggcggt
    21721 tccagtaact tcataaactc gattaccttg ttcaaacttt cccggtaata gtcctgctac
    21781 agagattcca tcccttgctg gcagtgcgat tttgattcct tcatcacctg ttaaggttgg
    21841 cgctacgcca tctgaaccat agacttgtcc acccattcct cgattggaag gattgatatt
    21901 taccaaattt ctgatgtttt gatcagatgt tgaagacggt ccaatgatag gaaatacttg
    21961 ttcggtacat gcgtctcgag aatgtccgat aaggaatatc cgctcccggc tttggggaat
    22021 gtaggccttt gagttaagca cctaccactc cacgtcatac cccaatccat ccagcgttcg
    22081 gaggatcgtc tcgaacgtag cccctccttc gtgattgagc aatcctcgga cgttctcaag
    22141 gaataaaagc ttaggtcgga gaagagtggt gaaccgagcg atttcaaaga ataaagtacc
    22201 tcgagtatcg gaaaatcttt gccgctttcc cgcaattgaa aaagcttggc acggaaatcc
    22261 gccgcaaagg atgtccactg gtccgaggga ttgaataaac tcatctgata cacttgtgat
    22321 gtcatgcatt tccacctcct tacttgtatc atgaattgct ttataactac gtctagcaaa
    22381 tttatcaatt tcacaaaaac cgatacaatg atggctcgcc tgttccatac ctaaacgaaa
    22441 gccaccaata ccggcgaata aatctaaaaa tctcatacat tacctcattc attgcaaaga
    22501 aaaaagccaa gaacattttg ctcttggctc atacattatt aatttgtcct actatttttt
    22561 atttaatcca actaatttcc gttgtttttc attggcctga tcggctacat atttaatcac
    22621 cgttttgaac tcttttgcag tagcattttc cgataaatcc gcaatgctct tattgtattt
    22681 ctttacaatt ttcgttactt gttctttctc agtcatgtaa ttgaacctcc aaatctttcc
    22741 tactataccc tagtggtaaa aataattcta gattatccgt agcataatga acttcggaaa
    22801 tattattcgt ataatctttt attatgatat gaagcaatac atctggatgt ttactcttta
    22861 cttttgcaat gttctctctt gatttgaaaa aagcgttaat aaatgccttt ttcggcacat
    22921 gacgtccctc tgcaatttca cgttcttgtg taaatttcca agcgatttta gggtcttgat
    22981 aaacatagaa aatcgtcact cgaaaatgtt ttttcaacgc ccgcgagata tttttttcag
    23041 cacttaatat tgcaaaagtt gcatccagaa taaaagaata gccatgatct aagacatatc
    23101 taaatgcctg ctctaccaac caagaagatg ctttttgaaa gagactagag ttttttccat
    23161 tataatcagg aaactgggtg cgaaagtaat ccgcatcaat aatcacatgg ttatcataat
    23221 tctcagctaa tccaatggca acctctgatt ttccagcccc aggactccct gccataaaaa
    23281 ctgcgtctcg tccaacttcg ggggatttcc ctttgataat ataagaaata aacttatcct
    23341 tatttgcttt tgcatactct aaataagaat cattactttc catattaatt atcccctttc
    23401 ttcctactat ataaaagtat tatacgttac ttgaagtata aagtcagtat tgaagatcac
    23461 tcaatcattc atcttttcta atttactaat tgaatctaag aaatcatacc cttttggtac
    23521 aagtggcgta taaaactcac taatcacact gccacctgta tccacataac ctcgaccttt
    23581 gatgtgcttc ataaagaagt ttttttcgac ctccccaaac atcatggaat atccgagttc
    23641 actcatacga cccaaagcca cgcgaaagtt gaattgatcg cggattccgt ctcctaaata
    23701 tttcgcatcc ggcctttggc aagccaaaat cagaaagaaa ccagattgac gacccaacat
    23761 cacgatttgt ttgagcttat tcaaaatcac cgcactttct ttcgtcgtta acatctccat
    23821 ataagccacg tattcatcaa agattaaaaa gttgggtgga agtccaagat aggcataatt
    23881 ctctcctgtt ttgtagttag acatttcttt cattgccttg ctacgagcca tcatacgttc
    23941 atagaaatct tccacacaag cagaaatttc ttccttttgt gaataaacat gaggcatcac
    24001 cgtacctaaa tcagctaaat ctgcattttt gggatcgagg ataaacaatt ctgcatctga
    24061 cttcaatagt gcttcgataa tggtgaggag gaaataggtc ttccctccac ccgtgccacc
    24121 agcgattaac atatggggta aagaatcata agcccatact tgatttttca tcaatcgcag
    24181 agtcccattt tctgccacta cttcgtctat cccaattcga ttggcgatca tatcatacag
    24241 taaagtatac tccacatagg agtctttgag ttccttttct actaactcac aatacagtcc
    24301 gctttctaac ttcttttcca attttaaaag ctgatcttgg tatttcccaa gtgaaatttg
    24361 aacgcgaata gacagtaatc catctttcat tcgataatag attttgggga agtaactgat
    24421 agtctctctg gttcggctac tattcaaatc tttgaaaaag ccttcacttt gagtttgttt
    24481 cacttcatac caatggttct ctagaatcat ccgagctagc ttttgtcgat gccacaagct
    24541 tcgccaatga tcaagaaaaa agtgaatata aagcaatatc atagctcctg aaaaagcgag
    24601 acttccaagc agacatacta aatcttttat agaccaaacg atttcaatag tagaaagtga
    24661 tagcttagaa atatcaaatt gtctaaactc ttgaaaataa aagacgctca tccaaccgat
    24721 gaacagagcg agtagccagc caagaacaaa gtgataaacc aagtgctgat ctcctgcgcg
    24781 tatgcgatgt cctttgtaca ttttgatggt ttccacctcc aatcgaaaaa gcccaatagg
    24841 atttcattag gcaatttcaa aaagttatgc tagtcattta ctgctacgag gaggggagtt
    24901 gtttcgtttc aaccaattga tttaaaaagc cttcaatagc atccggcatc tccacaccaa
    24961 tttcttccaa aatggattct gcctgccgac ataagttttc atttacttcg acaactataa
    25021 agaaagactc ttcttctcct aaccagtcta gtacatcaga gtcttcttca ctgtcgctat
    25081 tttctccaag taaaccttga tgtataatca gaaacatttt ttcatcagag gttaatgctt
    25141 taacgagttg ttcctcagtc agctcgcctt ttccatattg atcgagacaa tctaaaatat
    25201 gttcaacatt aatttccata atcttcacct atttctttct ttcattttgg ttcgtaggat
    25261 ttccttgatt cggctgccgc ttcaagacta aatcatccgc cttaatgaac caattaacgg
    25321 tagttccttc tcgaaaaaca taattggcaa cggtatccac gattggattg accaactcta
    25381 cctctgcatc ataagcaaac tcgcgtaagg gtacattagc tgggatacta acttgaatca
    25441 ttcgcccttg tgcagaggat tttaaattat aggttcgttc ttttacctca ttaccaattg
    25501 ttccatcctc attttgcttc cgtacttctc ggcgtaatgc ggaaaaacgc aacttcccaa
    25561 atgttaaacc tgaatctacg acaatacctt ctgttaatct catcttcttt tcctcctatg
    25621 ctttcactaa atcatcaaca tacaacacgt aatcagtaaa cccacgattc tcaatctcat
    25681 agcctttggc aaccaaatgg ggattcacgg cttttagcgg ttggtcttga tcaaaatcct
    25741 tttcaccggc ttccgcagct actaccacct caatatcatc ggcccgttgc ttactggaat
    25801 acaaatgata actgcgacca atcaccgtag tattccgtcc atatccttct gttataattt
    25861 ctccttcacc ggcataactt aactttccaa aggtttcagc catatctggc acgacaaatt
    25921 tcaattccat cttcttttcc tcttttcatt gttagttttg gatacaaaaa tagcgcgact
    25981 acttttttag gaggcggtcg cgcacgttgg ttcttaggat ttacttgtat catctcatca
    26041 ccttagttcc ggcgattcca gaaataatag cccgccgtcg caaaaatcaa agtaaaacca
    26101 atgaacagta aaacattgga atttttctcc ccggtttgag ggaaggtctt cactgtggga
    26161 ctagattctt gagagccact tggaacagtt ggtgtttccg gttgtttcgg cgtacttagt
    26221 atggttggaa cttcttttgg tgttaaggtt tgagattttt ctttcaaatc ttcattgtgt
    26281 tttccattga tattcccatc tttatcgtaa ttgatttccg caaaagtaaa cttggttcct
    26341 tctggatatt ttccggtatc tacttttttc gcaagcacag ttttggtgaa ttctttatca
    26401 tttacttcat aatcaatctt gccagatttc caaatttctt tgtttgtacc atccggtaat
    26461 aaagcataca gaattgtttc gaaagcttct tttgagccat ccagtacatc atgagtaatc
    26521 gacacatcat caaacatatc caccacatca ccatgagtaa aggtctgaga accgttttct
    26581 aggtgggcct ttgtttggat agaaacatgg tgttccactg tacaactgac agtttgggct
    26641 tggttattca agctaacatc cttcgctact ggcttatcgc ctgcttcaaa agcttcctta
    26701 ttttcataca catagttgaa taagacaata gttttattta aaacttgttc ggcggttaat
    26761 ttatgctgaa ttttccaagt tcctgttttc tctttgttcg ccaacgttgc gcttgtttct
    26821 gcaatcacca ctggtttggc tttttcatct ttttcttggg cagcttttgt cgcatccaca
    26881 tcaatggctt gcgctaccac ataccagtct tctttgattt catgtagatt gtaactcaat
    26941 ttatcaacta gctcggtaga atccagagaa gttaattctt tgtttccgtc tttccaagtc
    27001 gcaagagaag ttaaactatc ttcttcctca ggcaaatcat agagcattaa acggttcaaa
    27061 ctaacagaaa atgctttgtt cgtcagcttc tcgtaaggaa cggtcaccgt tttaattggt
    27121 tgtttttggt cttgttcggt aatggtaaag acatactcac tcttcacaaa gtcttctttg
    27181 ttttccttaa aagtagaacg gatttctaat ggcgtaatct tttgaaaacc ttctggggct
    27241 tctacttctt caagtaaata atccccataa ggaagatttt caaacttgcc ataaccatca
    27301 aaccctaatt gctcgttata agctgtggtc gcttcatctt cggcacctgt gatttcattg
    27361 gtcccttcca atggcgacac tttaaaggtc agatcatcga agccagtttc ggtagtgccc
    27421 gcagctgatc cagcaaattt aaagaaatca aagccaaagc gaatcacttg ttcttttgcc
    27481 gtaacatttc gggtaatcac ggcatttttt tcgctatcat ccaccttttt gatggataca
    27541 ggatactttg tttcatcaag gctatatcct tcgggcgctt ttgtttcttg ccaataatac
    27601 tcgttgatag ctaaatgttt aacggcaact tggttctttt cgtctaaagt caaagtgacc
    27661 gtttcatcag aacctttcgt tcccttcgct aactctggtt taaaagcctc actccattta
    27721 acagcttttc catccttagc agtaaacaag gtgtattcag caccctcaaa gactgcctta
    27781 ccttgtgctt tatccccagt atctttgtct tctttcgtca aagtggtttc gccagtgact
    27841 tcttgatttt gcccttttac gttactggta acaagggcta cggtttgatt ggcatacttc
    27901 aattcgactt ttacaggttt gaacgtattc acgaacccat gactagcttt agtttcggtc
    27961 acataatagg ttcccaattc caacgcatta gcaatctctt ttggtgtttc cgcatgaccg
    28021 ttttcatccg tggtcatttc ttgaacgatt tcaccggttg gactgtcttt gcgaatggca
    28081 aacgtattac cagctaagga ataattgtca ttccaaagat cactccctgt ttcaactccg
    28141 cttttatcca gaatgatttg ccctttttcc cgtgcgtttt ttgaagtcac gtaaatggtt
    28201 tcgcctgctt taatggtggt agtcatgggg gtggtatcaa tcgtataagg cgccggtact
    28261 gatttttcgg taatggttac ttttgtacca tgaggaatct catccaatgt agcaatgcct
    28321 tctttgtcag tagtcacgtc ttttgcaggt aaagtttttc caaagtctaa atggaaaacc
    28381 gttcctggta caacatcacc cgattcttta tcgacttttt tgatctttaa agaaccctcc
    28441 gtttccacat caattttgat tgtgtaggta ttaggtttat caatcgcccc ggccattaaa
    28501 gtctgttggc cagccttttt ataggcgaca ggtgttccgg taccagcaga tttcttaagc
    28561 gtcagcacac cactttcttt tgaattggca tttggggtga ttatcaactg attaccattc
    28621 acacgataat caatgtttgc ggcattttcc acaacctcat cgaactctga caaattcaga
    28681 ttattcgtat ccgtcacagt agtcgattgc cctaatactg ttttagccgt actattatgg
    28741 aaggttggtt tcttctgata atcgtcaatg gcttgattta tttttgcctc aatggctgcg
    28801 atatttacgg cactaccatc tgatcgtttt attgagtgaa gggtataccc attaacttct
    28861 tgccagatca tcttctgtgc cacaatatga gtatctgcat ctgtacctac ttttttccat
    28921 aaaacggaaa ctaatttggc tttatcggac atatctggta acgggttttt ctcatagcca
    28981 ggagtgaact cattgtaaat cgggactcct ggttcaatac agaaaatatc ttgtttaaag
    29041 ccgttgtaca ctgcataatg cggaacagtg acttctgaca ttggacgacc atcactaaaa
    29101 gttccttcaa cagcatattg atgtgctaaa tctagttcta cggttaccgt ttgtggatgg
    29161 gtaatttcat cagcaaaagt aatcgtagga gcaattgctc caacaattgc ttgaacagcc
    29221 aaactcaaaa tagttaatac acataatttc tttttttgtt ttttatacat gaaatgttct
    29281 cctttcaaat taagcacaaa aaaataagat gctcgcttga acatctttgt ttataaagtc
    29341 tttttaaaat ttttattgac tgaatagaat ggatttgaga atgaatgagc ctaaaaattt
    29401 aatctaaaat acgaaatata ctgcctttaa attagaacac attttagaac acaaacattt
    29461 caaatttaat caaatataat aaaatatatt tacgggaaaa cctttataaa tcaaggtttt
    29521 tcaaacttat tcaatgatac gaagaaacca ggtcttaaga aagcacgtaa agcttcacag
    29581 ttttcaaaac gttaatcgtt gttataccaa cgatttcaga cactttctca ttgcgagaag
    29641 gtgtcttttt ttcgttctgg taatgagaaa ggtaatgaca atattataaa ccagtgtaag
    29701 caatgaattt ttctaacgca tttcgttgag ctttttcagt aacatgagaa taagtgttaa
    29761 gggtagtttc agcattttta tgacccaatc gatcttgtgt ttctttgata cttgctccac
    29821 cttctagtag aagagtagcg tgagtgtgcc ggaatccatg aatagtaacg tgcttaaatt
    29881 tatatttctt ctctaaacgt ttcaatatat tatttgaata gtccgcatgc aaaggttgat
    29941 taatgtcacc gtctgcattt acataggtaa agataagttg attttttgta tttgtattta
    30001 tgccaaactg caaaagctct cgagcttgtt cttttttcca gatttttaac atttcaatag
    30061 tttgtgcatc aattggtaat attcgttcgg aagatatatt ttttgtattt ttttgaatcc
    30121 tgacagtttt tcttcttgca ttcttctctt catttcgaat agttgcatag ctctttctaa
    30181 catacattag ctgttcttca aaataaatgt cagaccaatg aagagcagct agctctcctt
    30241 tacgtatacc agtagtaatc aaaagctgga agattaaaat atgttttaaa ggctcttctt
    30301 tattgagaat atcccaaaaa gcttttagtt cttctaatga aaagtaattt tcattttctt
    30361 tcttttcccg ctttggtaga tttgtatttg ccataggatt tcggtgtaat agctctgcaa
    30421 aaatggcata ctcaaatatt tgagagctgt aagacttaag ctgtttgata ttcttgaatt
    30481 ttaaagccca ttcattgact gcattctgac agtgaacagg agtaatctta gaaatggact
    30541 tattcccgaa ttttggtagt atatgcaagc ggaaaaggtc ttttgtacgt tgatatgtcg
    30601 tttcttgtac acgattccta taagaaggca accattcttc atacactgtt ataaacaagt
    30661 cattagaagg cttatgatag ccggtatctt caatctcgac cttttttctt gcttcgtgta
    30721 acttggcttc tttttcagtt ttaaaccctt tttttacata gtattcttgc tttccatttt
    30781 catctttacg aacatacaag cggacactat atcgtgcacc gctttttgtt gtgtactttt
    30841 gtattgacat aactaatctc tccaatctga taacttggcg agttggctga ttgaagaaat
    30901 agaaaatgag aggagaaaaa taatggatgc aggaattaca gtaatgttag ataaacaaca
    30961 aacgaatcaa ttgaaaaatt atgtttttga aatgacaaaa gaggctattg atcaagcaag
    31021 aattgatgcc ggattagaaa gaccatttct aaaaggaaaa gagatggcta aatatttgaa
    31081 tgtatcatat acaacttttt tgaaatttaa aagaatggga ttgccagtta ttttattaga
    31141 aaaaatggag ttgttttcaa aagaagaatg caaaaaatgg atattgagtc atcaaattta
    31201 aaaaacacct cgttttttaa atttgatgaa gtagaaaaaa ttaaaaagag tgttcccgtc
    31261 agtttgcaga tcgggggaac actcaataat aaagttctga gaaaacttta tttgaatcta
    31321 ttatagcaaa taaaatcaga agcaggtgtg acaatgaatg aaaaagaagt tgaaagctta
    31381 gttgaaaagc aaggctattc taattctgat atatatgcag aattatacta tcaatatcct
    31441 atttttttaa acgtaaatga aaaatataag aaaatgaaac taagttctaa gttagtttat
    31501 atgttactaa aagatagaaa tagactttca ttgaaaaata acttgtatga tgagaatcaa
    31561 aaaatttttt tgatatttga aatcaaaaat ctcgtagaaa tttcgggaat gtcaaaaaat
    31621 acaatcttat cagcactaga tgaacttcaa aaagttaaac ttcttgtgaa aagaaaaaat
    31681 ggcttcaata aaagtaaaat gcaaatgttc ccaaattttt attatttgtt aaagcctgtt
    31741 ctgtgcaaag atgatgttta taaaattaat aagataaccc atcaagaaaa tagacaaaaa
    31801 aacttgatag ttcaaaattt gaactatgga acaaatcaat attctgttga tagttcaaaa
    31861 tttgaactat gcgacacatc aatgaaaaca agagacaaaa acaattttgc tgatagttca
    31921 aaaaatgaac tagaattata taagtcttat aaagatagta aagatattaa agaatcacat
    31981 aatgatgatc ttcttgaatc actttcaact aaaaataata aattagatga agaattgatc
    32041 gaaacattta ttgaagaaaa tcttcttaaa caaatatggg gagaaagtat tgtgaattgc
    32101 ttaaaactgg ctagcaatag tgattatcgt caattcgaca actggtacaa aaaattcaaa
    32161 tatgcgatta gatctgctga aaaagaacaa aaaattcaac tgaaaattat ctatgaaatt
    32221 tgtaataaca agtattttgt agatcatgtt agagaacagc tatcaatgac tttacgtgac
    32281 ttgatacgaa gagcaaaaac agatcatcgt atcaaacaaa aagacgatta tatctttgct
    32341 tctctaaaaa ataaagcgtt agaactaatt gaattgcaaa tcagcgaagg aatagataag
    32401 caataagaat agaattgagt caaatgaaat ggaggggtat ctccacttca tttgagaact
    32461 ttgaatatag gaggggttat tttgattaaa aatcgtttaa tagatcaagt ttggtgtcta
    32521 gatcaaaata cagatagtct cgaattaatc gagactattt gcttcaacac tatagttctc
    32581 gatttaagag ctgaaaatga taattgtgta actcatgtca taattaatca aaaaatggct
    32641 cagaagctct ctgagagcct cagaaaatgg gctaagggag gtaacgatga aaataattga
    32701 aaaaaagatt gccaataaaa aaataaattg gttggttgtt aattttcttg ttctgatagc
    32761 tatgattatt tttacaagta atattgctca tgcgagtatt ttcaattggt ttgatgacac
    32821 aaaaagtcaa acagagtttt tgaataattc tctttataga ccttacctaa aaaagtacaa
    32881 tggagatttc cttagtcagt tcgggatttg gctcggatgg gctgtggtaa aaggcatgtt
    32941 tactgtgaca gattcgattc aaaatatgat tccagatgtg ctggatttgt tcaatttcat
    33001 tgaaagtaca gggctaaata atgtttatca atcagccgta aatacaattg tcattggatt
    33061 aatgatcctt tcattgatgt ttgttggtta caaaatgatt actggaaaag gaacagtgga
    33121 tttaaaatcg gttggaatga acgtagtgat gtctatagca ttaatacttt taatgccaac
    33181 catgatttct agtggtattc aatttgctaa aacattttat aaggactcta ctacgattac
    33241 aaattcagat gacggagtcg cttggtcatt gataaaacaa ggagtaacag atttagcata
    33301 tattaataaa acagatcagt actcaagcat tgataaaacg gaggatcgaa ataatttaac
    33361 acgaaaaaat tttcaacaga cggatctcac acaagtgtta acggataaag tgattgataa
    33421 attggaaaaa gaaaatccaa ttgcggacaa tcttcgttat gaattagttg aaaattctaa
    33481 taatgaattt gttgctacaa agttttctga caacttctta tcaacatttt ctgatagctt
    33541 gaaatcaggc tattaccgat accaagcaaa tctatggggg atttcaattg ggttgacagc
    33601 gttagcaatc gcctatgtgt tcagcgcgtt tgtgatcatt acagcaatac tagaacttgc
    33661 atttaaacgt gtgttaggtg ttcttgtttt tgcaacagat attgagacag gacagcgttc
    33721 aaaagttgtt ctatcagata ttctacaatg ttacttaact gttgggtttc aaggatttgg
    33781 gttatcaatg tttgctatgt ttatcaattt tctgaactca ggacaaggta tctcaacaaa
    33841 tatttttata aaaacaattg cttatatctg tgccgttttt gttttaatca aaggcagtgg
    33901 aacagtcatg agatactttg gtgttgatat tggactcaaa gaaggctatg ggcaacttgc
    33961 ttctgctttt ggaatgggcg caatgctgtt tagaaaagga tcaaatggat ttaatcgtgc
    34021 taaaggaagc ggagaaggag aagatcgaaa accagaaaag aatttcggcg aaactctatc
    34081 aaaaaaagct ggcaaaactg gaagagcttt gggatatgcc catgaacgtg gattatccgg
    34141 tttagcttca gatggagcta caatggctag tgaaagagca acaaaaccat ttaagagtat
    34201 gcgtgatata gctaatgata ccaagaataa gtttaaagaa ggtttagatg atggtacagt
    34261 gtccgctatt aataaaaata gcaaacctat gttagctaaa aataaagaag atgaaactgg
    34321 aaaatatgct gattccgtgc caacacgtct ttcagataga aaagatggtg ctaaagttga
    34381 aaatgccgat agaattatgt ctagttctga acgtatgcgt gaagcaatga aaaataatgc
    34441 tgaatcgaat aataatcctg caagcgcaat tcagcaaaaa gtccaacaag atattgaaga
    34501 acgtaaaaat gctatgcacg gtcaagctaa gtctgctgaa gaattaatta atcagaagcg
    34561 tcatgaagcg aaatacacgc ctgaagcaat gaatcgcgag gaaataatgt taaggaaacg
    34621 tgtagaaggg cggacaggcg ctaatattga cggaaaagaa gcgttgacca aagaaagaat
    34681 tcaagaagct aaaaattcaa atacaggatt agaaaaatta gtcaaagaaa atccacaaaa
    34741 ttctacaagt agtcatggtg gccgatcagt agatgtccga gaaaatattc aaggttcact
    34801 gaatggtcat gttggacgga atgttgatgt aagagagaat ttacaaagtt cttcaaatgc
    34861 tcaaggtact aagacaattg atgttcgaga aaatctgcaa agtagcagta caagtcaacc
    34921 aaaaacagta gatgttcgag aaaatgtaca aaattctaca agtagtcaag gattcaaaac
    34981 agtagatgtt cgggagaaca ttcaaaaaga tagtggagaa atgaaagaaa aaacacaaaa
    35041 aatcaatatc gttgaagaca gaaagtcagc gaaaaaattt gattcaaatc atgaaacagt
    35101 gattattgat agtgaaatcc gtgaaaatga taagggatca aaatcaagac gaagattcac
    35161 ttatgaagac aatgagttat tcagagatac acttaatgat cctaatccac ttttcgataa
    35221 tttattaaga aataaaaggg ggggattgtc atgcaattaa ttctaaagat tagtacgcat
    35281 gatttcttag aacttgacga attatgtgaa tcagtaaaga acgcaacaaa tgaaaaaatc
    35341 acggtcacta attatattga actgatgatt caagaagaat taaagatgaa aaatgaaata
    35401 gagagcaatt tcaaatgttg ctctctagaa aaaaatgtga ggggataatc aatggatgat
    35461 aaacaaaaaa tgtacgaaaa aaatcgcaaa catagtgagg ccttaaattt tcgtgtcgat
    35521 aaaaagactt atcttgaact gacattgatt gcaaaacaaa ggggaatttc tagagcagac
    35581 gtttgccgtg agcggttaaa gggactcaaa tatgaaccgc cgttgttagc tgaagatgat
    35641 agggtagttt taaccaaaca gttaaatcaa attggtaaca atttgaatca agcggtaaag
    35701 gcattaaata tcattgctaa atattttaga gaagaatctg aagataaaaa agaaaagagc
    35761 ctacatttta gttttgatgc tagccgttac aacattttta aagatgaact tgcgaatagc
    35821 atagcaaaaa agttgatgat tagttatcca gatgacattt ttttggagtc caatcggagt
    35881 gccccctctt tttttaaatt atcagaagta gaaaaagaat atttcgaata ttggatagaa
    35941 aagcaaacta gaccgggtac gaaagaagag tattcccaaa aagttgatcg gaatttaatt
    36001 cactcaattc agattattgc aagtttaaaa gatgaggtga aacaactttg ggagctacta
    36061 taacatcgaa aggacgcaag aaaaatttat cctcgctatt acaatatgca gctaatcctt
    36121 caaaaaaaga aaaatgtgtt gcagtctcag gaataaattg tagtgatgat agtgaggaag
    36181 cactgcaaga aatgaattta gtacgtacca agatgaataa atctaaagat atagcacaag
    36241 cgtttcatgt tattcattcg tttgataaga gtacttctaa agagttaagt attgataaaa
    36301 tgcacgaaat agctgtcgaa tttgcagaga aagcttttcc aaattcgcaa atcattgttg
    36361 caagtcacaa tgataaagat cattttcata gtcatcttgt cattaataat attaacatgg
    36421 aaacatgtaa aaggttgcgt attgacccta aagatttaga actaatgcga aaaattaacg
    36481 atcaagtcct caatgaacat ggtcttgaat cagtgaataa tgagtactat gaaaacttag
    36541 aaaagagaac caatctttat tcaaacgatc cttctaagat gaaatatgga aaaattaatt
    36601 atcaagagtt tgtgcaaaat gcgatcgaag caacgttgga aaaatgcgaa gtgaattctt
    36661 ttgaagattt ttcggatcat ttggcaaaag aatataacat tgaagtttat caattttcaa
    36721 aaacaaataa caaacttggc tatgttcttt acaaacaagg tgtaaatttc tatgagcgta
    36781 gaggtgagtt aattacttta ggaagagata aacaatctag aaaagaaaaa agtcagtatg
    36841 tcgaacgtac ttttagtgca agaaagttag ggaaaagata ttcatttgaa tctgtttctg
    36901 aacaacttga aaagaattta gaagaatcac atataaaaaa tttttttaat atggaaagag
    36961 agcaagttat gtcgctaatt agtggagtaa attacaaaac tggtgagtta aatgtaccgt
    37021 ttgtggaatt agattccatc gcacaaaagc aatttagcga ccgtgaaggc gatgaaaaat
    37081 tcattaaata tgatgacttc ttgcgagagg tagacaagca ttttgtaaat acaatgtctt
    37141 tagaagatga tcaagaatac acgattaaac ttcatacgga tgtgaatcct caaactttac
    37201 gtagtgcgaa aagtaaaaca atttctatta aaaagactga tcagaaagag ttatttctac
    37261 cggcaaaggg ttttgaaaat tgttctcata caccttctgc taaacagatt cactatcaaa
    37321 tcagtcgcat aatgaatgac gatgtaaaaa tgtatcgtgc taaaaaggat tatgaattca
    37381 cacaacaaat gattgaaaat cagcaaaaaa ggcaacaaaa ttttgaaatg gaattctgaa
    37441 tgggcttgtt agtggacttt ccagtttttt gcctatgaag agttgcttgg aaagaagcag
    37501 tttttaggac atacgccagc tacccatcta cttgccagtc aatccgcccc gctcacgcta
    37561 ggctactttc tggcaagtca gatggcgggt aaatctctga gggagcaagc tccctacaga
    37621 ctccctccca aaaaaagaaa ggtggaagaa aaaaatgaac tatccatatt ttaaagtctc
    37681 ggcttcagaa gaaactaaag aaatattcaa caatttttac aaccaaaaca aaggaatttt
    37741 tggttcaaag gcaaatatgt ttcgtgttat ggtttcaaat ttaccagtgt tagctagtcc
    37801 atcaaataat aaatttaatg atcctgaaag cattaaattt gaacaaaaaa tttcagaact
    37861 agaatcaatg ataagtaatg aagtaattga aaagctggat gacattgatc aaaagttatc
    37921 gtattctcta aaaaacaaat acaaaacgga ggagaaaaaa gatgtttaaa gtttacttcc
    37981 cgtttcagtg gctcgttaaa ggaattcttt tagtgctact aggattgatt ctttttggaa
    38041 gttatctaac aattaaagcc agacattttc cagaagaaaa gccaataaaa attgtaacaa
    38101 aagatttaaa aataggtgaa acttatcagg cagatggggt tgaactaaca tttaaaaata
    38161 ttgaagtgac cgaaaaaaga aatgaatttg cacaacatga tcgtgtatta caagtgacct
    38221 atacacttat aaatgataca gaaaatccga tacgtccaca acaatggtcg attgaaaata
    38281 aggatggtga agaactttat gagtatgata tgatattgga taatccagag tatattgaaa
    38341 gtggcaaaga agaaacagta aattactatt atgaattacc gattgaaagg caggactacc
    38401 aaatcgtagt acgtagagag aatggttaca tagttgggtt gccatttact ttataagttt
    38461 tattttgtta gtagttttta aggtaatatc agttttgtga tttttgaaaa tggaactggg
    38521 agaatggctg aggaaaataa agttgttccg tttgaaacat tagtgataaa taaggaagag
    38581 tttgagcaac tttttcttga tttttttatt caatatgaca tgatttatga ttttagttcg
    38641 tcactagatt tatttgaatt agaagcagaa ataatagaaa acagtcgaga gaagaatggt
    38701 aaaatcatta tttcagtaga aaaattcaat gaattattct cacaaacatt tgaaatagat
    38761 ccagactatt atcaaccaca agaagttttt cgagagttta gaaataagat tattggtttt
    38821 agtcaaacta caaaatgaaa gcttaataaa gcaagtgttg atagaattat tcctcaacgc
    38881 ttgctttatt ttatgggcac ttcataatag aggtatagag aagagaggta ttcattttgg
    38941 atactattac tccaacaaac ttcaaagaaa atataggtaa agtgttgcaa gaagtagttc
    39001 attcaaattc tgaaatagaa attactaggg attctaaaaa tggattgaac gatggcgtca
    39061 ttatgatttc taagagaaaa tgggagttgt tacaagaaga actttattta caacgaacgg
    39121 gtacatgggc ttatgtatct gattta
//
LOCUS       DAFEIE010000021        38496 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFEIE010000021
VERSION     DAFEIE010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.021"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(67..942)
                     /locus_tag="LP345_001201"
     CDS             complement(67..942)
                     /locus_tag="LP345_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1759994.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            complement(1051..2820)
                     /gene="aspS"
                     /locus_tag="LP345_001202"
     CDS             complement(1051..2820)
                     /gene="aspS"
                     /locus_tag="LP345_001202"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBL1759995.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            complement(2835..4127)
                     /locus_tag="LP345_001203"
     CDS             complement(2835..4127)
                     /locus_tag="LP345_001203"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBL1759996.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            4521..5468
                     /locus_tag="LP345_001204"
     CDS             4521..5468
                     /locus_tag="LP345_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1759997.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            complement(5557..6816)
                     /locus_tag="LP345_001205"
     CDS             complement(5557..6816)
                     /locus_tag="LP345_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBL1759998.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(6987..7433)
                     /locus_tag="LP345_001206"
     CDS             complement(6987..7433)
                     /locus_tag="LP345_001206"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBL1759999.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            complement(7444..9657)
                     /locus_tag="LP345_001207"
     CDS             complement(7444..9657)
                     /locus_tag="LP345_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBL1760000.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            complement(9890..10654)
                     /locus_tag="LP345_001208"
     CDS             complement(9890..10654)
                     /locus_tag="LP345_001208"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBL1760001.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            complement(10655..11602)
                     /gene="prmA"
                     /locus_tag="LP345_001209"
     CDS             complement(10655..11602)
                     /gene="prmA"
                     /locus_tag="LP345_001209"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBL1760002.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            complement(11615..12103)
                     /locus_tag="LP345_001210"
     CDS             complement(11615..12103)
                     /locus_tag="LP345_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBL1760003.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            complement(12069..12740)
                     /locus_tag="LP345_001211"
     CDS             complement(12069..12740)
                     /locus_tag="LP345_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBL1760004.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            12878..14164
                     /locus_tag="LP345_001212"
     CDS             12878..14164
                     /locus_tag="LP345_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBL1760005.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKSAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            14236..14430
                     /gene="ssrS"
                     /locus_tag="LP345_001213"
     ncRNA           14236..14430
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LP345_001213"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            14508..14792
                     /locus_tag="LP345_001214"
     CDS             14508..14792
                     /locus_tag="LP345_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760006.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            14865..15344
                     /locus_tag="LP345_001215"
     CDS             14865..15344
                     /locus_tag="LP345_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1760007.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            15567..15710
                     /locus_tag="LP345_001216"
     CDS             15567..15710
                     /locus_tag="LP345_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBL1760008.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            16288..17871
                     /locus_tag="LP345_001217"
     CDS             16288..17871
                     /locus_tag="LP345_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1760009.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(18308..19492)
                     /locus_tag="LP345_001218"
     CDS             complement(18308..19492)
                     /locus_tag="LP345_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBL1760010.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(19517..20524)
                     /locus_tag="LP345_001219"
     CDS             complement(19517..20524)
                     /locus_tag="LP345_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1760011.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(20696..21055)
                     /locus_tag="LP345_001220"
     CDS             complement(20696..21055)
                     /locus_tag="LP345_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760012.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(21027..21398)
                     /locus_tag="LP345_001221"
     CDS             complement(21027..21398)
                     /locus_tag="LP345_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBL1760013.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            complement(21415..21717)
                     /locus_tag="LP345_001222"
     CDS             complement(21415..21717)
                     /locus_tag="LP345_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760014.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            complement(21734..22204)
                     /locus_tag="LP345_001223"
     CDS             complement(21734..22204)
                     /locus_tag="LP345_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBL1760015.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(22179..22457)
                     /locus_tag="LP345_001224"
     CDS             complement(22179..22457)
                     /locus_tag="LP345_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBL1760016.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(22454..23503)
                     /locus_tag="LP345_001225"
     CDS             complement(22454..23503)
                     /locus_tag="LP345_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBL1760017.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(23460..24389)
                     /gene="tadA"
                     /locus_tag="LP345_001226"
     CDS             complement(23460..24389)
                     /gene="tadA"
                     /locus_tag="LP345_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBL1760018.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            24521..26275
                     /gene="ade"
                     /locus_tag="LP345_001227"
     CDS             24521..26275
                     /gene="ade"
                     /locus_tag="LP345_001227"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBL1760019.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKEHLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(26373..27035)
                     /gene="trmB"
                     /locus_tag="LP345_001228"
     CDS             complement(26373..27035)
                     /gene="trmB"
                     /locus_tag="LP345_001228"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBL1760020.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(27105..27887)
                     /locus_tag="LP345_001229"
     CDS             complement(27105..27887)
                     /locus_tag="LP345_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBL1760021.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(28091..29302)
                     /locus_tag="LP345_001230"
     CDS             complement(28091..29302)
                     /locus_tag="LP345_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760022.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(29295..30032)
                     /locus_tag="LP345_001231"
     CDS             complement(29295..30032)
                     /locus_tag="LP345_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760023.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            30170..30604
                     /locus_tag="LP345_001232"
     CDS             30170..30604
                     /locus_tag="LP345_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBL1760024.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            30597..30941
                     /locus_tag="LP345_001233"
     CDS             30597..30941
                     /locus_tag="LP345_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL1760025.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            31121..32131
                     /locus_tag="LP345_001234"
     CDS             31121..32131
                     /locus_tag="LP345_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1760026.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(32200..33144)
                     /locus_tag="LP345_001235"
     CDS             complement(32200..33144)
                     /locus_tag="LP345_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1760027.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(33128..35848)
                     /locus_tag="LP345_001236"
     CDS             complement(33128..35848)
                     /locus_tag="LP345_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1760028.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            complement(35845..37065)
                     /locus_tag="LP345_001237"
     CDS             complement(35845..37065)
                     /locus_tag="LP345_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBL1760029.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            complement(37346..38191)
                     /locus_tag="LP345_001238"
     CDS             complement(37346..38191)
                     /locus_tag="LP345_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1760030.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
BASE COUNT        11397 a         7965 c         6719 g        12415 t
ORIGIN      
        1 aaaaaaactg cagacaaacg aacgtctgtc tacagcagta tttcatgaat ttttgtcaaa
       61 ctcgatctaa atgccatcct catagaaacg accaagtatc tggacgtttt ctgcaatact
      121 tacaaaagct tgtggatcag aagctttcat tgcttctcta agtagaggca gttcgtatcg
      181 tgtaacgatc gtcatcaata ctgtctgctt atcatgctta taagcacctt ctgcttcatt
      241 gatgatcgtg atccctctac gcatacagtt ttggatttca tttactactt tttctggatg
      301 tttcgttacg atcattacct gcatcttctt ttgtttagta taaacgacat cagttacttt
      361 tccactgacg aaaatagaca acgtactgta aaacatatat tgccagccaa atagaattcc
      421 ggcaacaaaa acgatcaatg cattgaagta gatcgaaata gaaccaatcg actttcctgt
      481 ttttttacga atcgtgatac tcacgatatc tagaccgccc gatgataggc cgtttctcaa
      541 cgctagccca atacctagtc ccatcacagc ccccccaaac aacgcacaga tgattggatc
      601 ggtagatagg actgtttccg gtaaaatatg gatacaaagg gaggtcaaag tgactgtgat
      661 aaaagtgaaa attgtaaact tcttcccgat ttttaaccac gccaatacaa acaaaggtat
      721 attcagtaaa tacaaagttg ttgataccgg tacttcgaat cctatcagtg attttgacaa
      781 agtcgtcaaa atctgagcta gaccagtaat accacttgaa taaatatgtc ctggctgata
      841 aaagaaattc aatgcgactg atgcgatcaa cgcataaacg atagataccg aaagcttggt
      901 cgtgtaatca tgataagccc aattttcgaa tgtttttttc atggaaaagc cccgctttat
      961 atgttatggc ttcattataa agtgtttttc aattaaatca aggttgtcaa aagaagcgta
     1021 ttcgacaaat cctttttacc tttttatcgg ctattcttct atattcgtta catcaatatt
     1081 caattcgaac aattgtaaag gcgaaaccat acttggtgca tcactcatca catctgctgc
     1141 ttttccgttt ttaggaaagg caatgacttc acgaatatta tcttctccgg ctaataacat
     1201 tgcaaaacgg tccaatccta atgcaatacc gccatgtgga gggaatccgt aatctaaagc
     1261 tgttaacaag aaaccaaatt gttcttccat ttgttctttt gtaaagccta gagtttctag
     1321 tactttttct tgaagctcac gagtatgaat acggatagaa cctccgccta gttcataacc
     1381 gttcaagacg atatcataag cttctgcata gacttttgca gggtcttcag ccaataacgg
     1441 gatatcttct tcttttggca tcgtgaatgg atggtgagca gagacatatc gaccttcttc
     1501 ttctgaaaat tcaaattgtg gccaatcagt tacccataag aaattgaatt tcgattcatc
     1561 aattagtcct aattcttttc ctaaacgtgt ccggatagca cctaatgcag cagcgacgat
     1621 ttcactttta tctgcgccaa acatcagcaa gtcacctggt tttgcatctg ttgctttaat
     1681 gattgcttct gttgcttctc ccatgaattt agcaattgga cctttcaatc cgtcttcttc
     1741 tactttcagc catgcaagcc ccttagctcc gaattgtcct acatattgac ctaactgatc
     1801 catgtctttt cgtgagtagc gatctgcagc gcctttagca ttcaatgctt tcacgacacc
     1861 gccgttttca agagccattt ggaagacttt gaattctact tctttgactg tatcgcttag
     1921 atcgatcaat tccatatcaa aacgtgtatc cggtttgtcg ctgccgtagc gagccattgc
     1981 ttcatcatag gtcatacgag gaaatggcaa tgtgacttcg ataccgcgaa cttctttcat
     2041 taccttcgca atcaatccct ctgtgtaagt ttggatttct tctgctgtta agaacgttgt
     2101 ttcaatatct acttgcgtaa attcaggctg acggtctcca cgtaaatctt catcgcggaa
     2161 acaacgaacg atttgataat aacggtcgaa tccagcattc atcagcaatt gtttaaacaa
     2221 ttgaggagat tgcggcaacg catagaaatg tccagcatgg acacgtgaag gaactaggta
     2281 gtctcttgcg ccttctggtg tagatttccc taggtaaggt gtttcgatat cgagaaagtc
     2341 attatcatct aaataatgac gaatcgcttt tgttgtcgca tttcttaatt tgatgttttt
     2401 agtcattttt ggacgacgca gatccaaata acgatatttc aaacgtattt cgtcactgat
     2461 tgcttgatca tcttcaattt gaaatggcgg ggtttttgct tgattcaaaa tcacgatttc
     2521 acttgcaatc acttcgaatt caccagtggc cattttagga tttactgcat tttctccgcg
     2581 tcttctaact tccccagtca cttcgatcac gtattcactg cgacatttat ccgcgatttc
     2641 ccatgcttct ttgttgattt caggattaaa gacgatttga acgattcctt cacgatcacg
     2701 taggtcgata aagattactc ccccaaggtc tcgtcttttt tgtacccatc cttttaatgt
     2761 aactgtttgt tctaattgtt gttcggaaac taatccgcaa tagatcgttc tttgtgccat
     2821 ttattttttt cctcctactc gaataaagtc atttcatcat agacttcatc aaaatgttca
     2881 tatatctctt ctaatggaaa acttttttct tttcggcttg ccattgcttt gacattaatc
     2941 gtttgactag caagctcatc ttcaccgatc accaatacta atttggcatt cgctttatct
     3001 gctgtcttaa attgcgcttt tgctttacgg ttcatgaagt cgcggtcagc tgaaaaacca
     3061 aagtttcgaa tcgcttggac cactttcaat gcttcgatat ttgtttcgtc tccgagtgcg
     3121 accacgtaag catccaactc attaaatgca gggataacta cttcctctgc ctccatagtc
     3181 aagagtaatc gctcgatacc cattgcaaat ccgaagccag gtgttgaagg accacctagt
     3241 tcttccacta gattgtcata acgtccgcct gcgcaaatcg ttgcttgtgc ccccattttt
     3301 ggtgcgtcac tcatgatttc aaaaatcgta tgtgtgtaat aatctagtcc gcgaaccata
     3361 ttactgtcga tttcataagg aacagccaat gcatccagca tggaaacaac ggtatcaaaa
     3421 tgtttttgag caggctcgct tagataatct aagatagatg gagcttctgc cacaaatttt
     3481 tgatctcgtt tgtctttact gtccaatacg cgtaatggat tttcatgaag gcggcgttta
     3541 gagtcttcac tcagctctga ttcaaaaggt aaaagatagt cgatcaatgc ttgacgatag
     3601 gcttgacgcg tttctttatc acctaatgaa ttgatgacta gccggatttg cgtgatcccc
     3661 aactgtttga agaaatcaag tgccatcacc atgctctcca catcagttgc agggttttct
     3721 gatccaaatg cttctactcc gatttgatgg aattgacgta accgtccttt ttgagggcgt
     3781 tcgtagcgaa acattggtcc catataaaaa gttttgaacg gtttcgcata ctctgggccg
     3841 aacaatttat gctcaacaaa agaacgaacg attggtgctg taccttctgg tcgaagcgtc
     3901 acatggcgtt cccctttgtc ataaaaatca tacatctctt ttgaaacgat atccgttgta
     3961 tcccctacac ttcgggatat cacttcatag tgttcaaaaa tcggtgtacg catttcatta
     4021 tactgataat ctctgaataa taaacgtgct gtttcttcga caaactgcca tttttctgat
     4081 tcgcctggca aaatatcatt tgttcctttt ggtctttgga aactcatagt tttctctccc
     4141 tttcttagct atgtaaataa aaaaatcacc cttgttcatc atgaacaagg gtgaatgaaa
     4201 ttcatacacg gtaccaccta attttgaaag atttctcttt cctcttacga ataacgctcg
     4261 tacgcgggac ggcttttcac tcgtccatct ccagagtgtc tttaggctaa tgaaacttta
     4321 gatcattttc agcctcgatg atcctctctt gtaaagtttc aaaaacttac tcgctctttc
     4381 attgacattc gatattactt ataacctact aaaaaccagt ctcaaagtca agagatatct
     4441 gactatttcc cctcacaaaa acgttttagt tcagcttttt ggtattttgt tttagactag
     4501 acaaaaagga ggaatcagct atggcagaaa taagaatcgg acattcacaa gtctacgcag
     4561 aacagcttgg attaggagca aatgccgttg gaggacataa tctttttgac ggtttggaag
     4621 atgagacagg aaaacaagta gttcgtacag ctttgaatag cgggatcaat ttgatcgata
     4681 ccgcttatgc ttacggaaac ggccgttccg aagaactgat tggcgaggta ctgaaggaaa
     4741 aagaatatga tcgctcacgt gtcgtcatcg ctacaaaagc tgctcatgta ccaaataaag
     4801 ggcgaacatt tgataattct cctgagtttc tcaaacaatc ggtggaagat gcactaaaac
     4861 gtctgcaaac tgattacatc gacatttttt atatccactt tccggatgaa agcacaccaa
     4921 aaaatgaatc agttgctaca ttgcacgaat taaaagaagc aggaaaaatc cgagcagtcg
     4981 gtgtgtcaaa cttcacgtta gaacaattga aagaagcgaa tgcagatgga tatgtcgatg
     5041 tagtagaaga taaatacagt ttgatccatc ggcaggctga aaaagaatta ttcccttatc
     5101 ttgaaaaaaa caaaatcagt tttgttccct attttcctct tgcttccggt ttgctgacag
     5161 gaaaatatga acttggtgag gaaaaacaat ttggtgaagg agatcctcga aaaagaaatc
     5221 cagatttcca aggagaacgt ttcagagaaa ttttaaccgc tgtcgatgta cttcgcccca
     5281 ttgctaaaag ataccaagcc actcctgcgc aacttgtttt agcttggtac atgaagaatc
     5341 cacgagtgtc tgtagttata cctggagcta agcgtccaga gcaagtatct gacaatgtcc
     5401 aagctttaga tttgcattta tccaatgaag attatcaaac cattgatgaa gcatttcgtg
     5461 gattttgatc aattgacctt atcaatttat agtaatatga aaaaaggaag atcagcactg
     5521 tttgatcttc ctttttttcg ataagtttat gctaatctaa ttcttgtaaa gtagcgctcg
     5581 gctattcgga taagtcggaa actgattgaa tggaatcgtc caatcttgtt caggtacaga
     5641 gaactcaaac ttatttacta gctgatcgga aaacacacgt agactatgaa gagtgatcca
     5701 ttctcctgca cagcgatgca tttgtcgaaa atttcccccg ccttgtgcaa tcatctcata
     5761 ttcttcttta taggaaatat cttttgcttt ccctacatac cgtttgatca taaaggaatc
     5821 tggcgcttca actgttcgtt catcatggtc tgttccatat aaatctaaaa taacccaact
     5881 gccttctggt atacgataac catctacttc tacttctttc agcgaaatcg caggtagcat
     5941 tgggaagaaa ggataatagc gtctcatttc ttgaataaac ggatcttgta acgtcgaaaa
     6001 gtcatttttt aattgctgat acaaatctgg tctactgaaa agtgcatgtc ccatcaatgc
     6061 cgcccacaca gttagagcaa ccgttggacg gatgatgttc aataattcaa cagctgccac
     6121 ttccagaggt aaaagctgac catctaaatc tgtggcattg gcaaaagcat ataatgccac
     6181 attttctttt ccagccacag gattttgtcg agcttcttca atcaagcctt gcgcccattt
     6241 ttctgatttt ttgcgatttt cgacaccttt tatgtgatca atcggagaag taaacgttcc
     6301 gctgatcata gagatttgat attctgctaa tttttcgacc tcatctttag aaatcgctga
     6361 taaattgata cctgcccact cgcaaataga tgtaaagaaa accatcttac ttaaatcaaa
     6421 tagttcaaat tgaccatgct gtgcttcaag tgcttgtgtc agattcttat ctaagatacg
     6481 atgataatct tccattcttt ccggtgtcat tagatccata aaaatatttt tccgatggtg
     6541 atgagcagct ccatccaaag tctgtactcc accttgacca aaaagtgtct tcaatactaa
     6601 ttttggcata gcaccttttc gtttgaaatt ccttggatca taaaatactt ttgctgctga
     6661 tgatccgtag atcgtgatag cttctttatt gaaaatcttt gctttgacga cgggagcgtc
     6721 cgcttcatgg cgtaactcct ccaacatgtt gtatcctttt tgatacaatt tttttaaatc
     6781 tgtgattttg atatctacta ctggtacttc tttcatcttc agcaacctcc tataaaaaat
     6841 aacttgtata atttaagctt aacttttttt ccgactgctg acaaaagaag cgctttttgc
     6901 agacaaaaaa gccacttaag ttagagttta tcagtctaac ttaagcgacg tgtttcatag
     6961 tttttactag tgaaaaccag attactttat ttgtttttag aatcaataat gatcgttaca
     7021 ggtccatcat tgacgagaga aaccgacata tctgctccga attgtccggt agcgactgtg
     7081 atgccgcgac ttctgattcc ttcattgaat gattcgtata aaggaatagc tgtttctggt
     7141 cgtgcggctt ccacaaagct tggtcgattt ccttttttcg tatccgcaaa cagtgtgaat
     7201 tgagagatac ttaaaatttg tcctcccaca tcttctacac taatattcat ttttccttgt
     7261 tcatcttcaa aaatacgcat ttgtgcaatt ttttttacca gatagtccac atctttttgc
     7321 gtatcggttt catgaatgcc taataaaaca agtaggccgt agccaatttt tccaatttct
     7381 tgctgatcga ctgacacagc agctttactt acccgttgaa caactgctct catatctgtc
     7441 ctcctatcca ttcgtccggc gtacactgta gacatcaggt actgctttga ttttatccac
     7501 gatactcttt aggtgggata aattctggat accaaccgtc aaatggatcg tcgccatttt
     7561 atctttattc gtccgtgctt caacgctgtt gagatttttc gttagcgcat tgactgtttg
     7621 aagtacatca ttcaataagc ctgaacgatt atagccgtaa atttccaaat ctgcatcata
     7681 ctcttttcgt gtattcgatg tatcttccca ttcgacttca atcaaacgtt ctgctacatt
     7741 tggtttgtca ggctgaacat tcggacaatc tcgacgatga atggatatcc ctctgccttt
     7801 agtgatataa ccaacgatat catcaccagg aatcggatta cagcagcgac tgatacgaat
     7861 tagtaagttt tctacccctt gaatgacaac gccaccttca tgacgtactt tcattttgtc
     7921 aggttctttt ttcggctgat tcatgatttc ttctgcttct tgcttttgct gctcgatttt
     7981 ttgttcttta cgttcttttt cagtcagacg attggccatc gtcaaggggc taacttctcc
     8041 ataccctaca gctgcataga gatcatcttc tgtttgataa ttaaaacgat cgagtgcttc
     8101 ttgcagtttg ttcttcgtca aaatatcttt aggcgtaaat cctagatctg taatacattt
     8161 gaccacggat tcgtggcctt tgatcacatt ttcttctcga tcttgggctt tgaagaaacg
     8221 tttgatctta tttcttgctt tgctagtagc aactaatttc aaccagtcgc gacttgggcc
     8281 aaatgaattt ggagaagtca tgatctcaat gatatctccg tttttcaatt tgtaatcaag
     8341 ctgcaccatt ttgccattta cttttgcacc agtggttttg ttaccgatat ctgtatggat
     8401 actgtatgca aagtccaatg gtccggatcc ttttggtaac tcagtaacgt ctccttttgg
     8461 tgtgaagacg tagactttat cactaaagat atctcctttt acgccttcca taaattcaga
     8521 agcatcatag ctttcgtctt gaagttcgag tatctcatgg aaccagctta attgtttcgt
     8581 cataccatct ggttctactt tttcattttt tccttcttta taggcccagt gtgcagcaac
     8641 cccgaattca gcgatttcat gcatttcctg tgttcggatt tgaatttcta ccggatttcc
     8701 tgccggaccg atcacggtag tatgcaaaga ttggtacata ttagcttttg gcatggcaat
     8761 ataatcctta aatctgccgg gcattggttt ccattttgtg tggattgctc ctaatacagc
     8821 ataacaatcc ttgattgaat ctacgatcac tcgaatagct agcaagtcat aaatttcgtt
     8881 gaactgcttt ttctgatctt tcattttacg atagattgaa taaatgtgtt ttggccgtcc
     8941 atagatttct gcaaaaatcc ccagctcttc tgtcgctatt cgaatatctt caacagtacc
     9001 acttacgtat ttttcacgtt cttctctctt cgtctgcatc aagtggacga tacggtaata
     9061 ctgttttgga tttagataac gaagtgctgt atcttctaat tcccatttga tccggctgat
     9121 ccctagacga tgtgcaagag gcgcatagat ttctaaagtt tcctgagcga tccttctttg
     9181 cttatcttct cgcaggtgct tcaacgtacg catgttatgt agtctatcag ctaatttgac
     9241 catgataact cgtaaatctt gagccattgc tagcagcatc tttcggtggt tttctgctag
     9301 ctgctcttcg tgggatttat attttatttt ccctaatttg gttacgccgt ccactaacat
     9361 agcaacgtca tcgccaaatt cttctctcag atcttctaaa gtgatttctg tatcttcaac
     9421 aacatcatgt aagaagcctg tagccactgt atggggatcc atttttaaat ctgctaatat
     9481 acctgcgact tggataggat gaataatgta gggttcgcct gattttctaa actgtccgtc
     9541 atgtgcagca gtcgcgtatt cgcatgcttt ctcaacaaat gctacatgtt cgggacccat
     9601 gtattgacta acgagcttta tgacaccggg tcccgttaaa atttcttctt ttgtcacagg
     9661 aatcgatccc cctttctttt ttcggtaaaa cgggaatcgg gacaaatatc tgtttgataa
     9721 ttgtcccaaa atccgtgcag ttatacgttt ttttacggaa atgttcgctt tttaaaagct
     9781 ttttcaaacg atttttcgta tccattgtat aaataattgt ttctattata caaattgttg
     9841 actatttttt caattctttc tgtcgatact cttttattaa tgaagaacgt tagctgaaag
     9901 aaggattcat taattcccat tgatagctag cagcacttaa taaataaaga ggtgctgttt
     9961 ctgtacgaag gattcttggt cctaatccac aaagtatccc tttgtgttct acaaaataat
    10021 cgacttcatc gcgggataat ccaccttctg gtccaaagac agctaagatt cgactatctg
    10081 gttttgtttc actaagaatt ttggctgcat ttgatttttc gccttgcttt gctgattcct
    10141 cataagcaac caagaccacg tcataatcat ctagccgctc aaataaatct tgtttcgttt
    10201 ccaataactc tactgatggc acgatctgcc gatgggattg ttccgctgcc tcttgagcaa
    10261 tcttttcaag ccgttgttgt cgtttcatac gtttttttgc atcccattta acgacagagg
    10321 ctgatgccgg gaaaccaaga aaagcttgcg ctcctaattc agtggatttc tgaacgatcc
    10381 aatccagctt ttccccttta ggatagccac tcgctatggt aatcgaactt ggcagttcct
    10441 tttgattttc ttctttttta atttctttca gataaacagc ctcttcagta atctccgtga
    10501 tttctgcaac aatggctatt tgatcattga atgccaaaaa aacttcatcc tcgggttcca
    10561 tcctcataac ccgtacaatg tggtgatagt tttccccttc taaaacaaaa tagtcttttg
    10621 attcatatga ttcttttaaa aaataccgct gcatctattc cacctctggt tttttcaaaa
    10681 taattgcata ccagtctttt tgctggaaaa tttgatccac gataaaccct tgttctaaca
    10741 tggcatccag aaccatttgc ttcttctctt caatgattcc tgaaacgatc agcgtgcctg
    10801 tttgcttcag taaacgccaa gcatctggga tcatcaataa gatgatatct gctaaaatgt
    10861 tcgcaacgat tacatcactt tcaatctcga ttcctgtcaa aagatcgtta gctgatacat
    10921 ggacatcttt ggctatttca ttcatatcca tattttcttt cgccgaacga acggctactt
    10981 cgtctaaatc aaaggcatag acatcttttg caccaagata ttttgctgca atacttagca
    11041 cgcccgaccc agttcccaca tctagcaatg tttcaccacc acgcaagact gtttctagtg
    11101 ctgtcaatgt caaggaagtc gtgggatgag tgcctgtgcc aaatgccata ccaggatcta
    11161 gtgtgataat tttttctaga ggatcttctg tctggtagtt ttcccagctt ggcgcaaccg
    11221 tcagcattcg cgtaatacgc accggatgat agtatttctt ccaggctgtt gcccagttgc
    11281 tttcctctac ttcactaact gttactttat tttttccaat agctagacca aactcaggta
    11341 attgtgtgat acgatctttg ataaaaggca agatttccgg taagaaagtc gtttccggaa
    11401 aataagccat gactagtgcg ccttctttca gcgatgtaaa atcattttta tctaaaatct
    11461 caccatattg atccgactga aaatgttcaa catctaaaga atcttcaatc gcgacaccac
    11521 tcgcccctgc ctccatcaaa atattagcaa ctgcttcgac tgcttcactt tcagtttcta
    11581 cttttacttc attccatttc atatctgtca ctccttaata acttgggtac ggtaaataag
    11641 tatctgcttc attttgctgt tttacttcta ctaattctgc tagttgctga ttatcccagt
    11701 gaagctcgaa tacagcttcg tcatcgtctt catccaaaaa atcaagcaaa tcgctttgcc
    11761 cttgagctaa tacttcattt agatattcca ctaaagaatc agctactgat tttgccaacc
    11821 ctttttttcc ttcataaggg attactgcta gataattgcg ttcatcaaaa acagatttct
    11881 gaggattaaa aagaagtacg ccgtcttcaa attcgataat tggttcttgc gaaacgatcc
    11941 cttctgcatc atcaatctca aattgtgctt tattttctgc aaacaagcga acaacgatct
    12001 cgatcgtatg attttttgta tcccaatcta aagctacatc atagtctgtc acttgttttt
    12061 caattatttc atctaaatat gttaatagat ccttcttttt cattttcttt cctccaaccc
    12121 caatctttct cgatttggtt ttttctttgt aaagagatat aaggatttcc cgacacaaca
    12181 aaacgcaacg gcttttctgt ccatacacct ttgtttggga taccgattct aggcaaagca
    12241 ttgatctttt ttggtgtctt ttttttctca aaaactaagc gtaacgaact atctgctata
    12301 gactgaccat aaagttcttg aggaattgct aatgcttcca ctaattttcc cggaccgttg
    12361 ctgatatctg gaccagtttt tccgccacga tttttactca tttgatcaat cattgcggcg
    12421 ggttcgattg cacgtatcat tactccttga ggaatccctt ctggctgagt aatgatgttc
    12481 aaaatccgat gagtatgcat cgtgtaaagg tagatcgtac ctggtttttc atacattgcc
    12541 cgcacacgcg gtgttcttct taaaccatag ctatgggcgg cctcgtcttc tggacctagg
    12601 tatgcttccg cgtctacaat atatccagct aatcttcctt ctggtgtgtc atgctccaaa
    12661 tacatcccca ataaatcccg tgccacttct ggcgtcgttt tattccaaaa aaattcatct
    12721 atcttttgtt tatccgtcat ttttctcacc tactttatca tacacaatat tagttggata
    12781 agctatgaaa acaaaacaac agaaggctgt tctttctagg catcttgcta aatatgatat
    12841 aattaaggga cgtaaaaaca agaaggagga aaatcctatg caacagccat tggcttatcg
    12901 catgagacct cgaacgatcg atgaagtcgt tggtcagcag catctagtcg gggaaggaaa
    12961 aatcatacgc cgcatggtcg atgctcgcat gctctcttcc atgattctat atggacctcc
    13021 tggtactgga aaaacgagta tcgcaagtgc gatcgccggc tctactaatt atgcatttcg
    13081 catgctaaac gccgctacag attcaaaaaa ggatctacaa gttgtagcgg aagaagcaaa
    13141 aatgagtggt acagtgatcc tcttattgga tgaagtacac cgattagata aaacaaaaca
    13201 ggattttctg cttcctcatt tagaaagtgg ccgaatcatc ttgatcggag cgactactga
    13261 gaatccttat attaccatca atccagcgat ccgcagccgt acacagatct ttgaagtcaa
    13321 accattaaca gaacaagaca tccagttggc agtcgaacat gctttaaggg ataaagaacg
    13381 cggccttgga caacaagcaa tccagttaga cgaagatgct cttcttcacc tttcgcgtgc
    13441 aacgaacggc gatttgcgga gtgcattgaa tgggctggaa ctggctacac tatcgactcc
    13501 ttcagataaa gaaggaagga ttcatcttac actgtcgatc attgaagaat gtgtccaaag
    13561 aaaagctctt acccatgaca aaaatggaga tgctcattat gacgttattt cggcttttca
    13621 aaaatcgatt cgtggaagtg atgtggatgc tgcacttcat tatctcgccc gtttagttga
    13681 ggcaggtgat ctggcaagta tttgccggcg tctgatggtt atcggttatg aagatatagg
    13741 tttaggtaat cctgctgctg cggctcgtac agtgaacgct gtattagctg ctgaaaaatt
    13801 gggattgcct gaggcacgta tcccactagc agacgtcgtc gtcgatcttt gcttgtcgcc
    13861 aaaatccaat tctgcctaca tggcattaga tgcagcactt gctgatattc gagagggcaa
    13921 agctggagat gttcctgatc atttgagaga tagccattac aaaggtgcga aatcactcaa
    13981 ccgtggcgtg ggttatcagt atcctcatca ttttgatcag gcttgggtca atcagcaata
    14041 tttaccagat aaactgaaga gtgctcagta ttatcagcca aaagatacag ggaaatatga
    14101 acaggctctg ggtcaacagt attaccgtat aaaagagtgg aaaaagcatc ctccaaaaaa
    14161 ctagacaaga aaacggttct gtttctgcga gctctctcat tgctcttttt aaattcatat
    14221 gctactatag aggtgggaaa tctgtgatgt tcgaattgtc ctctttgtgt gttgaccgaa
    14281 catttttatt gatatcttgg gacccgtctt gtgtcactgc tggtaacatg ccttatcatt
    14341 tggtagttcg aagctacgac catgggaccc acctgcttga attcgcggga tcaatactac
    14401 aggacaaaca acggcattaa cggagattac catcttttaa agaataaagc aatttgctct
    14461 tggcaaattg ctttttctat ttgttgctta ttttggagga tttgttcatg attaggattt
    14521 taatgattat cgccacttta gtattattat tcgttagcta ttatttattt aataaacagg
    14581 atatcttttt tgtattgatc aacaaaaatg ataaaaatca aggattccta caattttacg
    14641 gagctgcata tgctgtttta ggcgtaatgg gtattttaac agcttttttc aatcaacgct
    14701 ttattgcctt ggtcttttta ctgatcgtaa ttattgtttc tgccaccttc agtatccgat
    14761 ttgcaaaaaa aattgctgaa ccaaagcagt aaataattct ctttttccct aaagtgttct
    14821 acaataaaag agtacaatac gattgacttg aggagtgaat gcttatgtta caacaataca
    14881 aaaaaatcat ggttgccgta gatggttctg atgaagctga attagctttt aaaaaggcgg
    14941 tcaatgtagc tatccgaaat aacggagaac ttctattagc acatgtcatt gacacacgtt
    15001 ctttccaaac cgtttcatcc tttgatggaa tgcttgcaga acaagctact gaaatggcaa
    15061 agcaaacatt ggcagattat gaaagcaatg cgaagaaagc tggcttgaat aatgtaacct
    15121 ctgtcgtaga atatggctca ccaaaacaaa ttattgccag agaaatccca gaagataatc
    15181 aagtagattt gattatgtta ggagccacag gattgaatgc tgtagaacgt ttatttattg
    15241 gttctgtttc tgaatatgtt attagaaacg cagcttgcga tgtgcttgtt gtccgaactg
    15301 atttagaaaa ccaattgcca gctaaagacc acaccaaagc ttaacacgta gacgacctgc
    15361 caactatcgg caggtttttt tgcacaaaaa accgtgataa aaacaaaaga cgcggcaagc
    15421 actcatcggt ctttataatg tttaaaataa agggaaaaca gtcaatgagt tcaagtaaaa
    15481 taaaaaaaag tgaacaccag ggcgattagt cgccctggtg tggtttaaaa cgacctaagc
    15541 atgccaaagc ttattggttc gtcaatgtgg aagtttccga tgaatctgat acgaaaaaat
    15601 atgaagtatc gatggcggat accgatttta tcgccaaact aaaattttat ttcgggttcg
    15661 ggtaccgcga gaaggcaagt gctacattcg gtaaatcatt caagaattga tgaaaggcta
    15721 ccgcttgcca ttgcaaccac aacgatactc ctgaacgcga tgttggtgag atttccaaag
    15781 agaagagctg tttaatgcaa cggtattaag caaatggcaa aaggaagtca tgtagacaaa
    15841 gttttttatc aaacaccata tgatttcgcc tgaacgctgg tttagctcag aatacaatga
    15901 tgtggtccac gagacattac cctcagtcag ataaaaaaag ctctctgaca gaattacaca
    15961 tcgataaata ttaagtaaat gtcagcgcta gttgaacttt ctgacacttt caggtacact
    16021 ggaaaagaca actacacgaa ggagggaaaa tactatgatg cgcatgacta aaataacaag
    16081 taatgaaaat taccaacgat accatatcgc atttagccat gcaattggtt ttacagttgc
    16141 tgttgacggg acaagtttgt ccaaaacagt tgaattcacg taaaatcaat ggccatctca
    16201 aggtattttt ctcatgataa tctgagttta aataacacag gccatggata accatggcct
    16261 ttttgagtgg tctcaaggag agagatcatg atcatacaag caatttctat taaaaaaaca
    16321 atcggcggga atccattatt tgaggattta tcctgtcaaa ttgaagctgg tgaaaaaatt
    16381 gccttagtcg gtatcaacgg aactggcaaa tcaacctttt tacaaatctt gaccggcaga
    16441 gaaggtgtcg acagcggtgt tatcagtcgc aaaaaaggct taaagatcgg gacggtcgaa
    16501 caagaactta cagtttccga agcgaccgtc aaccactact tgctccattc tgccgctgag
    16561 atacaggacc tcaaacagca aatgagtcgc tacgaagcat tgatgacaga accagataca
    16621 aacttagaga agtgtctggc ccgttacggt gagctgcagc atcgctttga agaactaggc
    16681 ggttacgtat tagaagaccg gattgcagcg atcttgcaag gcttagggat tccacaccgt
    16741 caggaagcac ggttaacaga acttagcgga ggcgaacgag ttaaagtcgc tttagccaaa
    16801 attttagcag ccgatgccga tttactttta ctcgatgaac cgaccaatca tttagatctt
    16861 aacagtattc gctggttgga aaactattta cagaatacaa aaaaatcggt tctggtcgtt
    16921 tctcatgatc ggcaatttct cgatcaagtc accacaaaaa catgggaact ggaagaaggt
    16981 gcattgattg agtatcccgg aaactacagc cgttttcgag tcttgaaaga agctcgcttg
    17041 gctgagctga caaaaaatta cgaactgcag caaaaagaag tccagcggtt gaaagtcatg
    17101 attcgtcgtt ttcgtcagtg ggcacatgaa ggagacaatg agtccttctt caaaaaagcc
    17161 aaagaactgg aacgccgcct ggcgaaactg acactcgtca aaccgccacc tcccccgaaa
    17221 aatcggctgc aaagcttgtc taatggtgga aaatctggca aagaagtttt catcattcaa
    17281 aacttgcacc agcagtacgc tgatcaagta ctattcaaag acagcagttt tgcagtctat
    17341 cgtggagatc atttagccat catcggcgac aatggtgcag gaaaatcaac cttactcaaa
    17401 ttattactcg gtgaggaaaa gccttacggt ggcaccatca aattaggtag tagcttgcaa
    17461 atcggttatt tgccgcagca gctgcagttt gccgatcccg atagccgttt gctggcttac
    17521 gccatcacat tgactggaaa cgaagaagtc gctcgacggc aattagccaa aagtggcttt
    17581 tatcaaagcg atgtgggtaa acggatcaaa gatttatccg gtggtgaaaa aatccgtttg
    17641 gcgttgctga aactcttttt agaaaaaatc aacgtcctga ttttggatga accaaccaat
    17701 cacctcgaca gctatgctcg agaagaaatt gaagaaatgc tgcaagacta tcaaggaacg
    17761 ctcctagcag tcagccatga ccgctacttt ttgcagcaac acttccaaga agcactcgtt
    17821 attgatcagg agcagatcag ccgccagccg ctcggccaac tgattgacta ggacgttttt
    17881 tcgcaacaaa aaacttgatt ttcatacctg tgctttcacg attcaggcaa agtacaggtg
    17941 gaaaatcaag tttttattat tcgatcaatg aatgtttcgg atcggttttc tagctaaaca
    18001 taaagcgaag aataaagtcg acagcccacg aggctgatct aaaaatgttt tttcttttta
    18061 catatgtaat gtcccttata aagatgaatg aaaataaaat attgggattt tcctgaaaat
    18121 caataaataa aatgccagtc ttttcccttt tgaccacttt tccaagcaaa attccctaag
    18181 aagatcctgt aaaaaagaag ggaaattgaa gttaaattac cattttgcgg tcttctccgc
    18241 aaaaaaaaca catgcaagaa ttccctcttg catgcgtttc atcttttatc ctaacgaatg
    18301 ctttggctta gccgcgcaga cgctccacat cacgggcaat cattagttcc tcatctgttg
    18361 ggatcactaa tactcttact tttgattctt ttgtagagat atctacttct tcaccacgca
    18421 attcattcaa cgctggatcg atttcacaac caaaccaaga catacctttg atgatttcac
    18481 tacgtacatg tccgtcattc tcgccgatac cagcagtaaa gacaattgca tcaacaccat
    18541 tcatcgttgt cacataaccg ccgatgtatt ttcggatgcg gtccacgaaa atgtcataag
    18601 ctaaacgaat atgttctttt tcatagttct tttcaagatc acgcatatca ctagacaatc
    18661 ctgttaggcc tagcagacca gatttcttgt tcaaaacatt gatcatttca tcaatatcaa
    18721 tctctaattt ttccattaaa tatgggagaa cagctggatc gatatcacct gaacgtgtac
    18781 ccattgtcac cccagctaat ggtgtgaatc ccatagaagt atccatggat ttacctccat
    18841 cgactgctgt gatcgataca ccatttccta agtggcaagt gatgattttt agttcttcga
    18901 tcggtttgtt caataatttt gccgcacgtt ccgacacata acgatgactt gtgccatgga
    18961 agccatattt tcttactttg aaatcttcat aataagacac cggtaagcta tataaataat
    19021 tttgctttgg cattgttgag tggaaagatg tatcgaatac agccacactc aaaatgtcag
    19081 gtaaaatctt tttaaacgct ttgatcccca ttaagtttgc aggattatgc aaaggagcaa
    19141 attctgctaa ttcagcaatg cggtccatta ctttctcatc gatcactact gaatccccat
    19201 aagtttctcc tccgtgaaca acacggtgcc ctactccggt gatttcatca taagagctta
    19261 aaatttgcag ttcaatcaac tgatctaaca gcatttttac tgctacttcg tggttttcga
    19321 tatccatgat ttgttcgaat ttttgattat cgccgtactt gatggtaaaa atagaatctt
    19381 gtaaaccgat acgttcgacg atccctttcg caactacggt ttcttctggc atttgatata
    19441 attgccattt caaacttgaa ctcccagcat tgattgcaat tgttttagac atatgactct
    19501 ccttctcgtt gaatgattac agagcagatg atttccagtt tttaaactcg ttgaaaaatt
    19561 ccgtcacctt ctctggttct tttaatgaag caagtttcac aagcaagact tcttttactt
    19621 gttgtgcttg tggtcctttt ttctgtaaga tcaaaatact tttttgcgat tgtttattac
    19681 ggaacaattc atctggcaat tgaatcattc cttgaagata accttcttct ttaaaccatt
    19741 ttttgatttc ttcactttga tccgtttcta aaaatccact cggcatcaaa aacaaaccaa
    19801 aaccatccgg cttcacatat ttcattgatt gctctagcaa taaatgatgt gcataactat
    19861 ggccttcttc ggtacttgtt aaaaactctt ttgctttttc gtcattcgga taataaccga
    19921 ttggcaaatc gctgattgca aaatcgacag gatctattaa taattcctgc aacccgtctt
    19981 gatgaaagta ttgaacattt gcttgtgtca aatcacttgt agaagctgcg acagccaaca
    20041 atgtatcatc aatatccaca ccaattcctt ctgtttggta ccccgcattc gataggttta
    20101 aaagaactgt taataacaag ttgcccattc ctgccgcaat atccagaatc ttaaccggtg
    20161 cttttttatt tgtgtatagt tgttcaataa gaaaaacaaa taaaaaaccg atactatcag
    20221 gagtgagttg atggttcgcc tgcaaatgtt ctgtctggct gcccttcaat aaaagtaatt
    20281 gagacagtct gcgccattct tctggctcga aagaaagttt cttcaactct tcataaagag
    20341 ctgtgatccg ttgcgttgtc tcttttgtcg gcactccatc caccacacgt acttgataat
    20401 catctattaa attttctgca ttttcgacat aggcttctaa aaaggaagtt cccaatgcat
    20461 tctgtaaaag ctgaatagct tccaggtttt gattaaaccc ttgttccatt ttttctggta
    20521 acatggtgca cctcatttct agatatatta taacaatttt ttcacctgtt taattctatc
    20581 gaacaattga caaaatttca atcgttttca ctgtttttta tttgtgaaac ggcaaacatt
    20641 tttttattaa aaacagtgtt ataacagaaa agagggcgtt ttcacgaaca ttccatcatt
    20701 ctgtactagt atctgtatca ttttttactt cttctgtgaa ccgaaagata aacggtgaga
    20761 cttccacctc taagaatagg gactgttgta cccactgata tgttacagat ccagttgtgt
    20821 agtaaaaaac tccttccgaa ctttcggcaa gcgtagactg ttccgataaa gccatctgct
    20881 tcattatttt tgctatataa taatttttga ttcgtatatt aagatccatt gacaaacggt
    20941 agctttctaa tgctgccatc aataaaaacg tacataaaag aaataaaagc aagacagaaa
    21001 ataaaataga gcccttataa cattttctac tgatcgtttt ttgtccatat ggcatatcca
    21061 tcttctccat tttcaaagtg tacataaaaa gaaattgtgt gttctttttc caataattga
    21121 agctcagtga tacttgttaa cataggttga tgtccgccgg aagttcttct tttacgtatc
    21181 attgcctgat atctttcgat gatatactgt ttatcctcga tcgtgtagtg cagttgctga
    21241 tttttcacag agacattgtg actgctcttg agttcttctt ctaattgtgc taaaaatatt
    21301 agccactctt tttgatcttt acgctgcaaa aattcactta cttggatggt ttgctgaatc
    21361 aaaagattga atgtgagcaa tagactgctc aatatcatca gtccaattag acattcaatc
    21421 agcgtaaatg ctggaattac ttgttttttc aatactgatc gcttctttct ccatattgac
    21481 aaacactttt tcgattactc cattattatc gacaatttgg atatcgtatg ggatcatttc
    21541 ttcccttcgc tctggtcttt tgtgatacat ccgctgcgtc ttgatatctt cataaatcat
    21601 tcgaataaat agcagttcct ccccactttt cttttctgcc tgaagcaaaa acagctggcc
    21661 aaagctcact aagtagacac agacagaagc gatcataagc gctgtaaggg actccaacaa
    21721 aacaaatcct gttttattca attctttttg tatagcgacc actccctatc tggaattgat
    21781 acgtaatcgt ccgctctttt tcttcccaat aaaattgata agcttttagt gaactttcat
    21841 tcccggttct agcagcaaaa gtaatagaag catggcgttt caaggtaatc tcatcaggaa
    21901 tatctaatac ttcccaattt attttatctg gattcggaac atgaaaaatg atttgattct
    21961 cttcactatt ccaataaaag cctgtttgga tctgattcac aatagcgatt ttttgcgtag
    22021 aatagattcg tttttcaaat tggccgaaaa attgatagac tgccaattca ttcttccatg
    22081 cagaaaatgc gagaactgga aaagaaagga tcgttgtaag taataaaatc agtaagagtg
    22141 attcaaacaa cgtatatcct gatgctaaaa ccttaccttc aaggccgctg atagatttct
    22201 gcatgttctc gtttgatata gccttcattc aacaattcct ccacagtagg aactcttcca
    22261 ttattttgaa gcgcatagag ctctttttgt gtgtctacca actggatgat cgcttcacga
    22321 ctttcttggt ctacatgatt cctataacgc gacaaattag ggacgaacaa caacactaat
    22381 acactgatga tcagtaagac gattagcatt tcgatcaatg taaaaccgct ataataagat
    22441 atttttctct ttttcatggc aaaacctcct ctatgcttcc gtaaacaggt aataaaacag
    22501 cggcataaac taataaaatc aaagccgcta cgcccaaaaa aatgattggc tgaataaaat
    22561 gcatccagtg atgaagacgt ttgaaaagct gttttcttgt ccattcgctg taaaaaatca
    22621 gttctttacc taaacttccc tttgcctctc cctgtaaaac aattttactg aattcttctg
    22681 atagaaaacg ataattctgg aactgctcag ccaatgacat acctgcctcc aatccttgaa
    22741 tcaacttaga ggcaagatgc tgaatcagac tttcttgttt cgtttccttt aagcagacta
    22801 tgatttgcct taattcgaaa ccttcatgaa aaagctttcc aatctctagt gacaaataag
    22861 ccgattgata caaggaatat atcggtccaa tcaataattg tctgcttatc cattcactct
    22921 gatcaacagg agacaacttc atcagacgat accttactag taaagccaat agagtaaccg
    22981 ctaggatgaa tagtagaaca taccaatgaa agacttgtat cagctgaata ccccaatgct
    23041 cttgcatgac cattcctgaa ccaataagct gaggcaaaac gaacaaccgc atactaaaca
    23101 agatacctag caaaaaggtg agcaatagca tcggatatgc aagcagcttt ttcaaatcat
    23161 tgcgaaatcc ttcaacaagc cgaaactgtt tggcaatttc caacaaagtt gtcggcagat
    23221 tcccatgacg ttcagctaac tcgatctgta ccagttgctc tgctccatat cctatttgcg
    23281 aaagtacctc actaaacgct tgcccttcct ttagctgatg ttggatattt gccaaaataa
    23341 caggtggaaa cgaacggatc gtgagtaata aataaaggga ttcttgcaga ctaaaaccag
    23401 ataaaagcag ttctcccatg gtttgtgcaa actggttttg ctggcttctt gttaatcctt
    23461 tagaatagtt ctgactgcca aatattttcc tgagcttctt cataactttc ctcccatgat
    23521 ttttttactg attcttcctc cataaattga taactccata aaacagaagg atggtgattg
    23581 gcatcttcca aaagttcttg ataaatgaca ccagctaaac attcagatag ctcttctttt
    23641 ttctttgtca gttcatggat tctgaccaat gtaccttcaa gattgcgtgc atgtacggtt
    23701 gcaaaaaccc ggtgccctgt tagtgctgct cttaccgcag catgtgcagt tgattcatct
    23761 cttatctcgc caatgattag caagtctgga cgatgccgta atgcgagtct caaaagtgta
    23821 tcataagtct gtgctatttt cggattgatc tgtagctgca gaaaaaacgg ttcttctatc
    23881 tctacaggat cttcgatagt aatcacttgc aatttttctt ccaaagccaa ccgatacatt
    23941 agagaagtct tgcctgatcc gactggtccg ctgaaaaggt ataatccacg tctgacggtt
    24001 ttctgtaaaa tagttgcaaa atctcgagaa ctaaagcaac gatggggtgt ttcaaaagta
    24061 ccgtataata gccgaatcac taaactctct cgttgaaggt aatctcctac agaagacaac
    24121 cgcagacgaa cttcctgttt ttctaaagaa taagtaaatg cacctaactg agcttttctt
    24181 ttttctccga tatccatctg tcccaaatac ttaaatcttg agatcagttg ctgtccatct
    24241 gccgaagaga ctttcttcca gaatgttcgt ttttttccat agcgaaaata gatgtaaaat
    24301 acttctgaag ctggcaatat atatacgtct tgggcatgtt tggcaaaact ttcacttatc
    24361 atttgatccg ataatcgttt tatttccatt attctcccct ccacaaaaaa catacgtctt
    24421 tttgatcttt ttgtttcaaa taaaatgaat ttacaaaaaa atattggcaa aaaccgaatt
    24481 tatgttatac ttataaaaat ttatcttggg aggcactcca ttggaaacaa cattaaggaa
    24541 atatatcgaa gtagcaagta aaaaaaagcc tgctgaccta gtgatcaagc atgctaagat
    24601 cgtcaacgtc tttacgaaag aaatcatgga aaaagatgta gcaatctgcg aaggaatgat
    24661 cgtaggaatc ggtgaatacg aaggaaaaag cgtacataat gctaatgggc aatatctagt
    24721 gccaggattc atcgatggcc atgtgcatat cgaaagctca cttttatcac caagcgaatt
    24781 ttcaaaagta tccttgcttc atggagttac tactgtagtg acagatcccc atgaaatagg
    24841 aaacattgct gggagtacag gtcttgagtt tatgatagaa gatgcaagac aaacactcat
    24901 gaatatcttt tttatgctac cttcttgtgt acctgtaacc ccttttgaga ccaatggtgc
    24961 aaatttaaat gcaaaaaaat tagccccttt tttacaaaaa cccgaagttt taggcttagc
    25021 tgaagtcatg aactatcaag cagtagcaaa taatgaaaca gacatcctag aaaagatcca
    25081 attgatgcac cagcataaga aaaaaattga cgggcatgca gctggtatcg gcatggaaga
    25141 gttaaatgtt tatcctgcag caggtattcg gacggatcat gaagctacaa ctgcaaaaga
    25201 agctaaagaa catttggatc ttggtatgta tttaatggtt cgagaaggga ccgttgcaaa
    25261 agatctggca tcgctactac cggcgatcac acctgaaaat tcaagaagat gcttctttgt
    25321 caccgatgat aaactgatca atgatttagt aaaagaagga tcaatcgatc atatcgtccg
    25381 tcaagctatt gcacttggaa tcgatccatt acaagccatt cagatggcaa cattgaatgc
    25441 agcagaatgt tttgatttga aaacactagg tgcgattgcc cctgggtatc aagctgattt
    25501 cttcttaaca gacgatctta ccaagctgcc aattcatgaa gttttctata agggaacatt
    25561 agttgttcaa tctgggcaac tccaagacca tttatttgct gatcattcaa attcatatac
    25621 gtgttgtctg ccaaaactaa acgctcaacc attaaatcca cattcgttag agctgcttct
    25681 ttcttcttca caagcccatg tgatcgaaat tatcccgaat agtctagtga ctaaagattt
    25741 ggtagaaaaa gtggaccgac aaggcgaacg attcattcct tcaatcgaaa aagaccaatt
    25801 aaagattgcg gtgatcgagc gtcaccatca aacgggaaac attggattag gcatagtgaa
    25861 aggatttcag ctgaaacaag gagcgatagc gacaacgatt gcccatgact cgcataatct
    25921 agttgtcgtt gggacaaacg acgaggatat gctgtatgct gctaatcttt tgattcaaaa
    25981 aggtggcggg atgaccgttg tcaacaaaca gcaggaaata gcttgtgttt ctcttcctat
    26041 aggcggaatc atgacacagg aacctttttc gatcgtctat gaacagttga atgaattaat
    26101 aactaaagca catcaactag gagcagctaa aacctttgat ccttttttga cactttcttt
    26161 cttaacatta tctgtcatac ccgaattgaa gatcaccgac aaaggattat tttcattttc
    26221 tcgcttccaa ttgattccac cttgtggaaa aaccgatgaa ataaatacat tttaaatcaa
    26281 ataaatccca gaaaatacat tacatctgta atgttcattt tctgggattt atttatggat
    26341 attaatgttt ttatgaaagc agaaagttag tttcacagac ttttcttttt ggtcttatct
    26401 tgaaattgag cttctactcg ataaatacgt tgaccttttg aagaaaattt ttcttcatac
    26461 tccgtcataa tattgccttc aaattgactt tgatgtaaat ctaaccatac ctgtttgagg
    26521 atcatgccat attgagaaaa acttgccaga gaatactcaa acaatccttg attatctgtt
    26581 ttgaaatgga tttctccatt tggacgaaga atctgttcat ctacagcaag aaaagtctta
    26641 tatgtcaatc gccgtttttc atgacgtttt tttggccatg gatcggaaaa attcagatag
    26701 atttgatcta cttcgctgtc agcgaaatac tctgtcaacg ctgatccatc cacatgtaga
    26761 agtttcaggt taggaagcgg ttgttcgatc aacttgtcta gtgcaatcga aacaacactg
    26821 acctgcattt ctactccaat ataattgatt tcaggatggg cttttgccat tccagtgatg
    26881 aactggcctt tccccatacc aatctcaatg tggattggat gatcgttttc aaacaattca
    26941 ttccattttc ccttccacaa tgttggatca ctaattacaa aattcgggtg agccgctaac
    27001 atttccgctg ctcccggacg atttcggaca cgcattattt atctccattc ctttcctcta
    27061 attaaaaagg tctggccaaa tctccgcaga gtttgggcca aacctcagcc actgaaaatt
    27121 cgttttaatt gtaaaatttc ttcgttcatc cgtcgatgat cttcacgttt gcaatatctg
    27181 gtgatttctt ggagcaaatt catggccgca taccaatgaa atttttcaag catttcgtca
    27241 gtcgggcgta tgccataact gatcagccac tgattccagc tagacagtgg cacataattt
    27301 cctaaaatcg ttgcaatatc caccgcaggg tctgcaaaca tgattgaatc ccaatcgact
    27361 agatataaat aatttttaca tactaaccaa ttacgatggt ttacatctcc gtgtactact
    27421 gataagtttt ccttatctat tgacgggatc tgctcacgaa gaaaacgatg gacaatttgc
    27481 agaaattgat ttttctggag ttcttccggt aattcttttt catatttttg cagcatcttc
    27541 tccggcgtca tgacacgacc accgatacgg gtcagcatgg ttttaagaga atttgaatga
    27601 tgtaaatggt acaaaacatc aatcacgtcg tttctttgac caatctcatt aggagtcagc
    27661 aagcgacctt ccagccactc ttgtgctgtc aaagtatcgc cattccccgt tcgttttgtc
    27721 caaacaagtt ttggtgtaat tccttccctt gaaagagcag ccaacatcgg agtcgtgttt
    27781 cgtttaataa agactttgtc ctcatcacgc atgcctatgt atgtttttcc tgtgtcgcct
    27841 ttgatgggac gtaaccgcca ctcttggtct aactgaaact ccatcatgca ttctcccgtc
    27901 ctcttactct ttgttttgca gtacttatta ttctagtcgc ctgaacacta cacgtcaagc
    27961 acatatacgt tctttttcat ttaattgcca ttcaaaaaac cagcttttct caaaaaaaat
    28021 agaacgaaca gcattcttac tgtcaacgct ctatttttca ttctcatttt taccctacac
    28081 agctttgttt tcagtctgac atcttcttca aacgagttgg tacatatagt ttaacaaaga
    28141 gcatagtaac aatcaaataa gccgctagcg gaacccatcg ctgctgccca tctaatacga
    28201 ctgcagcaat caaaccaaaa ataaccgacg cgataattaa tacccatgtg agtagatact
    28261 gaatcgcctg cttcttctga ttcttatgga ttggataaag ctgaacgaga accatatagc
    28321 ggaactggtt cgctaaaggt aacagttgga aaccgatcaa atataaaaat aagaaaccga
    28381 taatcagact aaaataaaag tcgactactc cggcaatcaa taacccacct ataattacta
    28441 atcggaaata aagaccacta aaatcagaac ctcttgccaa tcttcttgca aacaagtaaa
    28501 gataagtgtt ttttgattct cttttaatat gagtcaatat aggatccaaa tagcgtcttc
    28561 ttttgatctt tgccgtaatt tcaggaacat ctgtgaataa attgataaat tgatagatct
    28621 gatgcaacct atgttcttct acatgcacca ttttctccca atccaatcct ttttcttgtt
    28681 gcttccacaa aaaccagtaa tatagacttg cctgtactaa tgcacctgct attcctgccc
    28741 atattagcca ataaaatgat agaaacaaaa agatcagaga agaaaaaaac cagcctaatt
    28801 tccaataacg aataacttgt tgatctagtc gaaacaattc tgctctcttg atttgcagat
    28861 gactgaattt caaactccat aatatgatca gatagacgaa aaacatcgaa aaggattgct
    28921 ccgtactaac caccactaat ggcatggcca atccgcatgc caatatcaaa aagatcaacg
    28981 gaaaaatgca agaatagcga aaagctcgtt ccaaataggt ttgcatttct ttttctttag
    29041 gaagtaaaaa aacaatatct gctgcctctg caaaagtagc catcttaccc acgaataaac
    29101 agagcatcca aaatacagag attatgagcc ctccaattgc aaacggtggc tgcagggttt
    29161 tcaaccaatt agaataatat aatcccacac cgccaatcaa gaaaagacaa actaaaacaa
    29221 aatgatcgtt caatacataa cgcatatatt tcatcatttt cttttgatgt cttgctaaac
    29281 gtttttgaaa aaaactactc atgtgcctgc tcctttgtta aagcaatata gatttcgtcc
    29341 aaagaagaat ccggcagctg aaattctttt ctcaacatct caagagaacc gtctgctcgt
    29401 atctctccgt tatgtaagac cacaaaacga tcacaatatt tttctgcagt agctaaaata
    29461 tgcgtagaca tcaaaatacc ggctccttct tttttcattt ctaccatcaa ttcaagcaat
    29521 gcattgatag ctagtggatc caagcctaaa aatggttcgt cgatgatata taaagaaggc
    29581 tcgatcaaaa aggcgcataa gatcatcact ttctgtttca ttccctttga aaaattagct
    29641 gggaaccagt caagacgatt agataaccga aaagtctcca acaacttttc tgctcttttc
    29701 attgctatat ccataggtat atcgtaggcc atcgcagtga cttcgatatg ttctctcaat
    29761 gtcaattctt catataaaga aggagtctct ggaatatacc caatttgttt gcgatattct
    29821 tccgtatttt tctttaagga tagatgattg atttctatcg ttccttttga agcttccagc
    29881 agaccgataa tgtgcttgat ggtcgtactt ttccctgctc cgttcagtcc aatcaaccct
    29941 actatctctc caggctgtac atcgaaactg atatctttta acacagggag atgtccgtac
    30001 ccccctgtga catgatcgat aattaaactc attctttttc ctccgccatt tatttttatt
    30061 tattatacca cgaagaaaat gacggtattt tgtttttttc cttacaatag ctttaactta
    30121 tggtaaagtt aagctgaagt atttattctt tatagaaagg atgttttata tggaaaactg
    30181 tattttttgc aaaatcatca atcaagaaat cccaagctat aaaatatatg aagacgacaa
    30241 ggtctatgct tttttagaca tctctcaagc aacgaaagga cacacattag ttgtgcctaa
    30301 acgtcatgta gcagatattt ttgaatatga tcccgaactt gcaggagagg ttttttcgcg
    30361 tgtgcctaag attgctcaag cattggaaaa agcttttcca gaaatgaaag gtcttaatat
    30421 cttgaataac aaccgtgaac tagcctatca atctgttttt cattcacata tccatttagt
    30481 ccctcgctac agcaaagagg atgatttttc tattcacttt gtcaatcatc aagatagtta
    30541 tggatcggaa gaactaaaag ctattcaaga aacaatcgta aagcaggtgt cctgcgatga
    30601 ttaaaaactt tttcaaagga ctgttatttg gagctgctgc tggcactgtc ggaggtctgt
    30661 tattggcgcc caggagcggg aatgaaacaa gaaagaaact gatcgaagaa ttggaagaag
    30721 caacaactct gacaaatgat ttaaataaca gcctgaatca ttttaaaagc gcattgatcg
    30781 aaacaaaaga aacagctgaa tctgtgattc ctgctttcca agaagcaatc aaaaaagata
    30841 tcgaagattt taaattccaa gccgaaccac gtatcacaca aatcaatgaa caagtagaaa
    30901 aactaaaagc tgatctgcca gagtatcctg aacaaatata ataatgatta ttttctcaac
    30961 agatttaact atataagtga gaaaagtttg cgtatttcct aggaatgtga tgaaattttg
    31021 aattttgttt gaaactacca cgacaacgtt tttaaaggaa atgggatatg gtatagttaa
    31081 tatataaaaa taataactaa ttacaggagt gcaaatttta atgaaaaaaa aatcaattat
    31141 tttggcagct actagtgcgt tggctgtttt aactctagca gcttgttcag gcgatactaa
    31201 taaagatatc gcaacgatga aaggcggaac gatcactgta tctgatttct atgatgaagc
    31261 aaaacttgaa tcatcgaacc aatccttagt acaacggatg atcatttata aagtattcaa
    31321 taacaaatat ggcgataaag taaccgataa gcaagtggat gcagaatacg acaaacaagc
    31381 gaaatcatta ggtgatactt ttgaatcaca attagaagct gctggatata cgaaagatac
    31441 ttataaagaa tatattcgta acaatttagc ttttgaagct ggcttgaaag ctcacgtaga
    31501 tattacagat gacgatttga aaactgcttg gaaatctttc catccagaag tagaagcaca
    31561 aatcatcaaa ttatcaagtg aagatgaagc aaaagatgtg aaaaaatcag cggatgatgg
    31621 agatgatttc tctaaattag ccaaagacaa atcaactgat acagagacaa aagaagatgg
    31681 cggtaaagtt aaattcgact caacgacaac aactattcct gcagaagtaa aagaagcagc
    31741 tttcaaattg aaagacggtg agatctccga tgttattact acaacaaatc ctacttctta
    31801 tgcgacagaa tactacgttg tcaaaatggt gaaaaaccaa aataaaggca atgacatgga
    31861 taaatacaaa gatcaactaa aagatatcgc tactgaaact aaactaagtg acaatgcatt
    31921 cacaactaaa gtaatcggtg aagaattaaa agatgcaaat gtaaaaatca aagatgatgc
    31981 ctttgaaaat gtgttgagtg cattcacaac aacttcatca agtacgaaag actcaagtga
    32041 aactacagct tcaacaaaga gttctgacac aaaatcaact gattcaacaa aagaatcttc
    32101 aactgaagaa acaactgatt catcaaaata aaagaaaaca aaaaaagcga agacttatgt
    32161 ctcgcttttt ttgttttgaa tgaaaaaaat aaatttttgc tataaatctt ttggtacata
    32221 gaaacttcgg ttgtccatac cgaaaatccg atcggtgtat tttcctggtt ctgtttgacg
    32281 aatcgaagtc aacatcatct gcatcgaagc atcgatattg tcgatttgat gtaatatttc
    32341 tgcttccatt attcttggac gtacaggtga gccatattct aataagccat ggtgtgctaa
    32401 aaccatatga cgtaatacga gaacatcttc gtcagcttcg ctgattttca acgcaagaca
    32461 ggctttagtt atttcttcgt caatcaatac cagatgaccg atcaaatttc ctgcaagcgt
    32521 atattctgtc gacataggac cggaaagttc aatcaccttt cctaaatcat gcaaaatgat
    32581 accagcatac aacaatgctc gattcagctc aggatattca tcggcgattg atttccctaa
    32641 gtgaagcatt gtcaaagtat gataagctaa tccactggca aatgcatgat ggtttctttt
    32701 tgctgccgga aactcaaaaa attgtttttg atatttatta agtagatagc gaacaatacg
    32761 attccaatgc gcattggtga tctcaaacaa caattgattg atttcttctt ccatttcttc
    32821 tttcttcaaa ggggctcttt ccatgtataa actaggctct cctggctcat ctacccttgt
    32881 taagcgcata tgaagaatct ttacttgagg gtttccttga taaacctctc ttttaccgtt
    32941 tagaaaaacg actgtgccgg ctgtaaattt attgatttcc tcctccgaag catcccagta
    33001 tttaccatcg atagtacctg aagtatcttg gaaagtaaaa gcaataaatt tttttccgtt
    33061 tttagcgatt cttacatctg cacttttgat caggacaaat tgttcaaact gctcatcgat
    33121 tactaaatca cgaatttttt tcattatttg ctccttctaa ttgttttacg atttggttca
    33181 tctcatggta atagcttacc atttctttat cagaagaaaa acaaattatt tgatactttt
    33241 ctccaaattt agctaaaagt tcagctaatt gatactttcg ctgatgatca taatgaagcc
    33301 agccatcatc aatgatgatc gggcatatcg aacggttagc ttctaatgag aggtaagcaa
    33361 atctcatcgc cataatcagc tgatctttcg tacctgtaga taactcatag atgggaaatt
    33421 ctgtatatcc gtctgttaaa gtcagtgtat catttttcag taatatcttc tgataatttc
    33481 cttttgttaa aatacctaaa taatcacctg ctgctcttaa caactggggt aattgtcttt
    33541 cactcatctc tgttgaaaga tcacctaaga atgtcccggc gatttcaagt gctccccatt
    33601 cctccagtaa ttcctgtaat tttgcttttt gccggctagc ttgttgataa agttcgtcca
    33661 atgtgccgtc tctttgcaac tcttctactt gaagttggag tcgttgccga ttttcacttg
    33721 cttctttttc ttcttgctgg agttgggatt gcttttcttt cagttggcgc agtcttacag
    33781 ataatttctc ttttgtcagc tcttcaggaa atagtggagt aagcatttcc gataattcat
    33841 tgtatctttt catctgctgt tcggcttgtt tggctttttg taaaaagaca ggtacttccg
    33901 aaggataaga taagcctgct tgagtcaatt gttcgctgta ttcttgtatc catacttttt
    33961 gtttcttttt caattgattg atttcttgct tcaataaagt attttgctga tagcttctgg
    34021 caaatttcat ctgttccatc tcttgtataa aacgggaaag caataccatt ttttctgaaa
    34081 ttgtcttatc ttgtatcggt aaccattctt taacaaactc aaatttttgg tcgatttgtc
    34141 gtagtttttc ttgtatttcc tgttctcttt tatgtttccg ctcaaatacg ccatataatt
    34201 tctgataatc tatgacttcc tgtccatatt ctttcatgag tttgagcgta tccatctttc
    34261 ctaagtgccg atgatccgca aaacgatata cttcttgctg aagaatctgt ttttcttctc
    34321 cagttctctt ttgtttttct tctgcttcag ctaattgagc taaggctaga tcaagttgtc
    34381 ctagtttttc ttgccacatt ccttttatct cagagaaatc atttttagtt ttaatttttg
    34441 gttgcctttt gtagaagaaa tagccaatca tgcctgcacc aattagtaaa aggatcactt
    34501 tcaagggcat tggtacaaat atacctgcaa tgattattgc tccgccagcc atcagcatat
    34561 acggtttaga tgaagagact ggtgctatct ctgactgatt ttgtaataat gctggatagg
    34621 tctcttccaa gtcattcact tctgcttcaa tcatctcttg ctgttcttta gctatttgga
    34681 gacgcacaga aatctggctt tctagatcag caatccttct ttcttcagcc agaagatgct
    34741 tccattcttc ttcatataaa aattcttccg gtaacggatt tttctgccaa tgccaccttt
    34801 gttccaaaat cttcaattct gaatttgttt ctctagtctc aatttgtaat ctttgccatt
    34861 cttcgtttaa ttgttccgct gtaaattgaa gttgctggag atcttttagt tcctgctcct
    34921 gctctaaata aaaataatat ctggctgact gctgatccat cccgctatgc ttttccagtg
    34981 ttgcttctaa ttcttccaaa cgctcatttg tttgctgata ccgtttggag aaagactcca
    35041 gatctaaaag aagttgctca tcaggaagac ctgtagtgct gttttttttg agagattgcc
    35101 attcttcata taaagaaaaa ttaagttctt gctgtctggc taatgaaaat tgtttgttcg
    35161 cctcttttaa ttgtgccaat aactgctgct gttgcgactc gtattcctgt tcttgttgga
    35221 tcaacttgcc aaaataagct tcctgttctt gtttttgatg aattttttct tgcagctctt
    35281 tccattcatt taatttttga ttgattagta atttttggcc ttttttcttg aataattgtt
    35341 gtgctttctg ataatattct tgccgctttt ggaatacttg agaactgccc gtgatgccta
    35401 aagaaatcag cgcatcatgt agctcttttt ctctcaaatg atctagttcc atcaactgct
    35461 cttgctggaa agtaaatacc tgctggaata actctttcgt caaaggtgcg atcagttttt
    35521 ctagtaactc atcacttccc acttgatccc ccagccacac cttcgatttt ccgcgatttt
    35581 gctgcttgta gcgctcgaca gcaaattcac catatacagg atgtttaagc catattttgc
    35641 cgccataggc tgagccgtct tttggtgtat aatccttttt tttacggcct tttgaaggga
    35701 aaccaaataa tattgcttga ataaattgat aaatcgttga ttttcctgct tcgtttcccc
    35761 catagatcag ctgattgcct gaataaaagt caaaactttt ttgacgccat tttccaaaag
    35821 cagcaatctc gatccttaaa atcttcattc ctgatcctcc tcaaataaaa aatcttgatt
    35881 aagcagctgc ttggcttttt caagtgtttc ttcttgatat tccggcagtt cgctcaatat
    35941 tctagccgct tcttgatgac tatatacttc atttaaaatt tgttggaaat cttgaggtgt
    36001 ctgatagtat tgaaataact gttccatcaa tttagcagaa gcagcaagtg gggtcttcgt
    36061 ataaaaagta ttctctatga gagaaatacg ccaaataaag aaatcattta tcctatctga
    36121 gaattcctct aacaaatagt ctaatagctc tcctgattgt atccgttcca aaacatctgt
    36181 attgagatgg tcataatctt ttaattttat ctcaattaaa ctaaatccat cctctacttt
    36241 tgaaagctgc tgacgaatgt gaacaatgac ctcttttgtc gttcttgctt tcctcaatga
    36301 tatttccttt gtcttccaat agacctctgc tactttaatc ggatgtattt ggcaacttcc
    36361 tttacttaat tcaactagta gaatagatgt agaagcttgt tcctttttag tatgaccttg
    36421 aggcgcacct ggataaacaa ttgtttgctt ttcatttaag accgttggca catggatatg
    36481 ccctaaagcc caataatcgt atcccttttc ttgcatcttt gagggttgga aaggagcata
    36541 gtttcctttt tgagagacgc caggttcccc gtggtacaac ccaatatggt aatctgtgag
    36601 ttctctagaa ggaaattcca tcactttgtc tttttgaatc cacggttgac gataactaaa
    36661 tccactgaga gagacagttt ctccactttt tatcgttatt ttttttgtct ctaccgtttc
    36721 ggatgtaaat aaatggacat ttttaggaaa ggagaaccaa taccgctctt tttgatagaa
    36781 atcatgattt ccgaatatta taaatacagg tatatggttc ttttctaacc gtttcatctg
    36841 ttctgaaaaa tgtttctgta tttttaatga aggacgattt tgatgaaaat tatctcctgc
    36901 aagtaaaaca aaatcaacgt tatttattat tgcctgttca atgatatttg ataaaacggt
    36961 cagattcgtc ttcaatagtt tttcctgtac agttttatca agagttgtca gtccttcaaa
    37021 tgaccgatcc atatgtaaat ctgccgcatg gataaatttc accattaaaa atttcctcct
    37081 ttttttcttt tatcatacca ttttcaatgt tttttttcat caataaccga aaatttgttc
    37141 gtattatgca aagaaattac gataaatggc cgacttcaaa aaataagttt attcgaaaaa
    37201 aagattgtga catgattttt gtcacaatcc taaatatcta tgttatattc gcttcgtttg
    37261 acactgaaga agtactattt gtactggaat ttatgctcca tttttccgta tttagaattc
    37321 tatgttctat actaccttaa ttagtttata tggtaagaat tctttcaaat gcttgagata
    37381 ctccgtcttt atcatttgaa acagtgacat aatcagcttt tttcatgatt tcttgatgac
    37441 tatttcccat tgcaaaacta atatctgcac tttcaaacat agataagtca tttaaactat
    37501 ctccgatcgc gattctcaaa ggtttcttta aattgtagat tgattccaaa cgatcaaaca
    37561 ccacaccttt agatacattt tgaggtacga tttcaatatt tacaggtgcc gattcagtaa
    37621 cagacacatt tagcatcttt ttcaaatggt taaatatatt agctttcaat tgacgattag
    37681 gaataaaaat aaaaaatttg taaatgctga tagcatcctt ttctataatt tcctcaatat
    37741 tattataagg gattgaacaa atagattttt catactcaag ctcatagttt agctctttga
    37801 tagaaaattc actccctacc tcgtgaaaaa tttttttcat tttattttta taattctgag
    37861 attcataact tccgagattt gtatatattt tggttggaaa tttcgatagg acagaatcaa
    37921 ttttttttac atcattttta tcgaaggaag actcaaatat ctttttttct ccatcaaatc
    37981 caacagaacc atttaaccct actgctggta tccttaaacc agattttttg agaatattat
    38041 taatgtcttc tacttctctt ccagaacaaa tgaatggaaa acagtcttcc ggtaaatgtt
    38101 tcattgttct tgcatttttt tgactaatgc tctggtcaga attcaaaaga gtaccgtcta
    38161 aatctatacc aattagtttc atttcatcca tgtctcctat acgttgatta taaattcact
    38221 gcttattgta agtctaaatt tctcacaaaa catatactaa ttatacctaa tttaagtaag
    38281 tacaaacatc attttaagaa taggaaagga catttatata ctattctctg tatttttgat
    38341 ttataaataa atatgaattg aatccaaatc agctatatta ctattttata ataaccaact
    38401 ataaaaaacg aagttaggtg aaaaactaac ttcgatattc ataaaagact ctattagttc
    38461 aacttagcaa aagatttaaa caaaaaaaga tgaact
//
LOCUS       DAFEIE010000022        38327 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFEIE010000022
VERSION     DAFEIE010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.022"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            154..384
                     /locus_tag="LP345_001239"
     CDS             154..384
                     /locus_tag="LP345_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBL1760031.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            481..1782
                     /gene="murA"
                     /locus_tag="LP345_001240"
     CDS             481..1782
                     /gene="murA"
                     /locus_tag="LP345_001240"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL1760032.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1795..1971
                     /locus_tag="LP345_001241"
     CDS             1795..1971
                     /locus_tag="LP345_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL1760033.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2106..2402
                     /gene="yidD"
                     /locus_tag="LP345_001242"
     CDS             2106..2402
                     /gene="yidD"
                     /locus_tag="LP345_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBL1760034.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2586..3053
                     /locus_tag="LP345_001243"
     CDS             2586..3053
                     /locus_tag="LP345_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1760035.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3138..4022
                     /locus_tag="LP345_001244"
     CDS             3138..4022
                     /locus_tag="LP345_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1760036.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4136..4372
                     /locus_tag="LP345_001245"
     CDS             4136..4372
                     /locus_tag="LP345_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBL1760037.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4460..4540
                     /locus_tag="LP345_001246"
     tRNA            4460..4540
                     /locus_tag="LP345_001246"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4494..4496,aa:Tyr,seq:gta)
     gene            4547..4618
                     /locus_tag="LP345_001247"
     tRNA            4547..4618
                     /locus_tag="LP345_001247"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4579..4581,aa:Gln,seq:ttg)
     gene            4743..4913
                     /locus_tag="LP345_001248"
     CDS             4743..4913
                     /locus_tag="LP345_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760038.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5133..5840
                     /locus_tag="LP345_001249"
     CDS             5133..5840
                     /locus_tag="LP345_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1760039.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5900..6544)
                     /locus_tag="LP345_001250"
     CDS             complement(5900..6544)
                     /locus_tag="LP345_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBL1760040.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6671..6958
                     /locus_tag="LP345_001251"
     CDS             6671..6958
                     /locus_tag="LP345_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760041.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7066..7386
                     /locus_tag="LP345_001252"
     CDS             7066..7386
                     /locus_tag="LP345_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1760042.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7467..8780
                     /locus_tag="LP345_001253"
     CDS             7467..8780
                     /locus_tag="LP345_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL1760043.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8777..9496
                     /locus_tag="LP345_001254"
     CDS             8777..9496
                     /locus_tag="LP345_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBL1760044.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9624..10175
                     /gene="raiA"
                     /locus_tag="LP345_001255"
     CDS             9624..10175
                     /gene="raiA"
                     /locus_tag="LP345_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBL1760045.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10397..12931
                     /gene="secA"
                     /locus_tag="LP345_001256"
     CDS             10397..12931
                     /gene="secA"
                     /locus_tag="LP345_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBL1760046.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPHHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13057..14158
                     /gene="prfB"
                     /locus_tag="LP345_001257"
     CDS             join(13057..13128,13130..14158)
                     /gene="prfB"
                     /locus_tag="LP345_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBL1760047.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14263..14949
                     /gene="ftsE"
                     /locus_tag="LP345_001258"
     CDS             14263..14949
                     /gene="ftsE"
                     /locus_tag="LP345_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBL1760048.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14933..15826
                     /locus_tag="LP345_001259"
     CDS             14933..15826
                     /locus_tag="LP345_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760049.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15978..17426
                     /gene="cls"
                     /locus_tag="LP345_001260"
     CDS             15978..17426
                     /gene="cls"
                     /locus_tag="LP345_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL1760050.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGGKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17763..18620
                     /locus_tag="LP345_001261"
     CDS             17763..18620
                     /locus_tag="LP345_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBL1760051.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18735..19655
                     /gene="pstC"
                     /locus_tag="LP345_001262"
     CDS             18735..19655
                     /gene="pstC"
                     /locus_tag="LP345_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBL1760052.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19655..20539
                     /gene="pstA"
                     /locus_tag="LP345_001263"
     CDS             19655..20539
                     /gene="pstA"
                     /locus_tag="LP345_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBL1760053.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20554..21360
                     /gene="pstB"
                     /locus_tag="LP345_001264"
     CDS             20554..21360
                     /gene="pstB"
                     /locus_tag="LP345_001264"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL1760054.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21376..22134
                     /locus_tag="LP345_001265"
     CDS             21376..22134
                     /locus_tag="LP345_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL1760055.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22147..22824
                     /gene="phoU"
                     /locus_tag="LP345_001266"
     CDS             22147..22824
                     /gene="phoU"
                     /locus_tag="LP345_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBL1760056.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23062..24093
                     /locus_tag="LP345_001267"
     CDS             23062..24093
                     /locus_tag="LP345_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL1760057.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSFLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            24090..24857
                     /locus_tag="LP345_001268"
     CDS             24090..24857
                     /locus_tag="LP345_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL1760058.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24957..26525
                     /gene="liaX"
                     /locus_tag="LP345_001269"
     CDS             24957..26525
                     /gene="liaX"
                     /locus_tag="LP345_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBL1760059.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26822..27142
                     /locus_tag="LP345_001270"
     CDS             26822..27142
                     /locus_tag="LP345_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBL1760060.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27142..27492
                     /locus_tag="LP345_001271"
     CDS             27142..27492
                     /locus_tag="LP345_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL1760061.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27659..28597
                     /locus_tag="LP345_001272"
     CDS             27659..28597
                     /locus_tag="LP345_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBL1760062.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28612..29442
                     /locus_tag="LP345_001273"
     CDS             28612..29442
                     /locus_tag="LP345_001273"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBL1760063.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29486..30511
                     /locus_tag="LP345_001274"
     CDS             29486..30511
                     /locus_tag="LP345_001274"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL1760064.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHHASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30526..31464
                     /gene="galU"
                     /locus_tag="LP345_001275"
     CDS             30526..31464
                     /gene="galU"
                     /locus_tag="LP345_001275"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL1760065.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            31589..32029
                     /locus_tag="LP345_001276"
     CDS             31589..32029
                     /locus_tag="LP345_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBL1760066.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            32032..32634
                     /locus_tag="LP345_001277"
     CDS             32032..32634
                     /locus_tag="LP345_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL1760067.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQGLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(32697..33800)
                     /locus_tag="LP345_001278"
     CDS             complement(32697..33800)
                     /locus_tag="LP345_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL1760068.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            34010..35011
                     /gene="ccpA"
                     /locus_tag="LP345_001279"
     CDS             34010..35011
                     /gene="ccpA"
                     /locus_tag="LP345_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBL1760069.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            35366..35761
                     /locus_tag="LP345_001280"
     CDS             35366..35761
                     /locus_tag="LP345_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760070.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREMQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTCSYRIVILMTNKQDQSIYFSYSFWKERNEIGSY
                     GIVDEKKQKEGNTLNKVKVTYSNGNEESI"
     gene            35761..36012
                     /locus_tag="LP345_001281"
     CDS             35761..36012
                     /locus_tag="LP345_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760071.1"
                     /translation="MITDKQYSELSDAVYWLDPKHRDYVPEMQENLSFKINGTMYKIL
                     KIKNSFDGMQAMAVAPIVHSKLEKNFKNKKIPANFRVLK"
     gene            36055..36450
                     /locus_tag="LP345_001282"
     CDS             36055..36450
                     /locus_tag="LP345_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760072.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGSYGALVTMTNNEGKSVYFDYSFWKERNELGGF
                     GIENRAVQKTGVTIKRVKVIFSNGQEELV"
     gene            36447..37703
                     /locus_tag="LP345_001283"
     CDS             36447..37703
                     /locus_tag="LP345_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HBL1760073.1"
                     /translation="MTINDKHYNDISEKVYWLDPKYPRYNEGYKKNSVKEFAGMEFQI
                     LQIKDSLDGMQAMSVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGQLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            37715..38038
                     /locus_tag="LP345_001284"
     CDS             37715..38038
                     /locus_tag="LP345_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760074.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            38031..38297
                     /locus_tag="LP345_001285"
     CDS             38031..38297
                     /locus_tag="LP345_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760075.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNYQ
                     MTAEEAAQEFSNRHVHLKGSVKGQFAEKLTELFQRQEKKLKQFR"
BASE COUNT        12859 a         6513 c         8259 g        10696 t
ORIGIN      
        1 cagtcccttt ttttgcatat ttttagcatt tatttcctaa aaaatgtaag gggattccta
       61 tatttttaag tatacttgtt tttcctttta tacattttat ggtattatca ttttattagt
      121 tattataaaa caatcgttag aaaggacgtc attatgcaag tatacggaat tgatgcggtg
      181 cttcgaatcg tgagtcattt ggcgtttatc tacttagcct tctggtcttt acgttcgtta
      241 cgcattgaaa cttttttcag accaatgcat aatacgcaaa ttagaatggc aatcgtactt
      301 ttttcaattt ttttagggta cactgcaagt aattttttct tagaagttat cgctttatgc
      361 cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta ctattttaaa agcaaggatg
      421 ttataataga aaagattttg agtaagtgta tgctcattgg aattttttgg agggaacaac
      481 atggaagaga tcatcgtaag aggtggcaat caattaaatg gaacagtaag aattgaagga
      541 gctaaaaatg ctgttttgcc tattttagct gctagtttgt tagcagaaga aggtattacg
      601 acattagaca acgttccgat tctttctgat gtcttcacta tgaatcaagt gattcgtcac
      661 ttaaacgtag atgtagattt tgatgaacaa aagaatcaag taacaatcga tgcttcaaga
      721 caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa tgcgtgcttc aatcgttgtg
      781 atgggtccgc tacttgccag aaatggacat gcaaaagtag ctatgcctgg tggatgtgcg
      841 attggtaaac gaccaatcga tttgcattta aaaggatttc aagctttagg agcaaaaatt
      901 attcaaaaaa acggctatat cgaagcaatt gcggatgaat tgatcggtaa cacgatttat
      961 ttagatttcc ctagtgtagg tgctactcaa aatatcatga tggctgccgt aaaagcaaaa
     1021 ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa tcgttgattt agcaaacatt
     1081 ttgaataaaa tgggcgctca agtctatgga gctggtactg aaacaatgcg tattgaaggc
     1141 gtggatcatt tacatgcagt caaccactca atcgtacaag atcgtatcga agcaggtacc
     1201 tttatggttg ctgctgcaat gacacaaggc aatgtgctga ttgcagatgc tatctctgaa
     1261 cataaccgcc cattgatttc taaattgatc gaaatgggtg cagaaatcat tgaagaagaa
     1321 ggcggagtcc gtgtcatcgg accaaaacat atcttaccta cagatgtaaa aacgatgcct
     1381 catcctggtt tccctacaga tatgcaagct caaatgacag ctatccaatt agttgcagaa
     1441 ggtacaagtg tagtgactga aacagtgttt gaaaatcgtt tccaacattt agaagagatg
     1501 cgccgtatga acgctcatgt caaaatcgac ggaaatgtag caatcatgga tggaaaccat
     1561 gaattgcaag gtgcagaagt atatgcaaca gacttgcggg cagcagcagc attagtttta
     1621 gctggcttga aagcaaatgg aatcacacgt gtgcgtaact tgaattatct agaccgtgga
     1681 tattataatt tccatatcaa actacagcaa ttaggtgcag acgttgaacg tgtagacatg
     1741 gatcaaactt ctgctgaaaa aacagcacaa acgattgctt aaggaagtgg ctgaatgagt
     1801 aaccaacgat atatcttatt aactttgata aagattttag tggtgatctt attgcttatc
     1861 cttctttttg tggccggaac gatgatcgga tatggtgtca tcggtggcgg caatccattt
     1921 aaagtattcc agccaagttt gtggattcat attcgagact tttttcattg ataaataaga
     1981 atcacagtgg ttctagtcga tatgaagtga gccatgaagc agaacatgac aaaagaaaac
     2041 agaagggaac gttgacgtta gtcgcgatcc ctttttttag taaaagaaaa gaaggaatct
     2101 aattgatgaa gaagatattg atttatttag ttagaggata tcagcgcttt atttcgcctg
     2161 catttccacc tagctgccgt tattacccaa cctgttccaa ttatatgata aaagcaattc
     2221 aaacccatgg tgcactaaaa gggacggtaa tggggactgc acggatctta cgctgtcatc
     2281 cttttgtcaa aggcggtatc gattatgtac cattgacatt ccaattaacg cgaaataaga
     2341 aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa tacgagtagc actgagcgat
     2401 aaagaaacaa tttggaaaat agcttcttat attttgcaaa attgtgagtt attgccgaag
     2461 tgttggattt tgaacaccgt caaaaaaagg ttgtgaaaaa tacgggtagc actgagcgat
     2521 aaagaaaaag aggaaaatta ttgtcaaagt aacaactccg caactactta tatgggggac
     2581 aaaaaatgat cgaagaacta aacaagaaag atttaccatg gtccttgtta ttagatgcag
     2641 atcctgataa agaaaaagtt caagtatatg tttccagagg gagtggctgg atatggaaag
     2701 aaaaagaaaa aacaataggt gtactgatct atgtggcaag ggaaaaagaa tacgaaatcg
     2761 tcaatgtagc agtagcccca acgtatcaag gaaaggggat tggcggaaaa ttacttgaga
     2821 cagcttttca gaagctttca caactcgctt ccagtcaaac tcagatcatc atacgaaccg
     2881 gcagtactag cagtgcggcg ttacatctct atcaaaaaat gggctatgtg gagattggtc
     2941 gagtcaaaga ctattttatc catcattact ctgagcccat ttttgaaaat ggagatcaat
     3001 taagggatca agtaatttta gcaattcact tacctaaaaa tagctttaac taataaactt
     3061 tcaattcgag aaaatgcttt caaatgctaa atagatacat tacaatagct ttagcaaaca
     3121 aaaaggagaa tatttttatg ggaatattag tttttgattt tggtggatcg gctgtcaaat
     3181 atggttgttg ggatggcaaa gagattaaag gtaagggaca atttgcaacg cctgaatctt
     3241 gggaagaaat gaaagcgcaa ttatttcaag tttataaaaa aatactcgtt tcttttgaag
     3301 tcgaaggaat tggaatcagc tctcctggag tagtgaataa tgagaaacag gtgattgagg
     3361 gaatcagtgc gattccttat attcatggat ttaatatttt ccgagatttg gaaactctgt
     3421 ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc cggaatggct gaattttatg
     3481 aaggtgctgc ccgtgattat caagatgttg cttttgttgt ggcaggaact gggattggcg
     3541 gggcgttgtt cacgaaagga caaatcaata aaggggcaca tctttatggt ggagaatttg
     3601 ggttgatgtt cttaaatggc gataagacat tcagtaaact tggtacagcg gtacagatgg
     3661 cttggcgtta ttgtgaacgc aaaggtctcg ataaaaattc ttataccgga aaagatgtct
     3721 ttgaattagc agaaactgga gatgcaatag caaaagaaga agttgagagt ttttatacgt
     3781 atcttacaaa gggattattc agtattcaat tttcgtttga tccagaagtg atcgtattag
     3841 gcggcggtgt ttctgcaaaa gaagggctca ttgatgagat caaaagccga atgaagaagc
     3901 tgacagaaca attcgatctg catgatttcg aaccgcagat tttattatgt gaatacagaa
     3961 acgatgctaa tcttgtaggt gcagcagcaa actatctcgc tgtacgtcaa ggggagaatt
     4021 aagagcttta gagaaggtgc agcttgcata aaagaagtga atgaaatgaa taggagattt
     4081 ttacctaagg aatgttttat ttgctgcagt atgataaaat atctgagagg tgaaaatgat
     4141 gtcaaaaaaa aataaagatg ttgaagtgcg tatagaagaa gtgaaaaaag atatcaaagg
     4201 taagaattat gaagtcactc agttatttat agggaaaaaa atgattggtg agatcttagc
     4261 ctatgggcca aaagaatatg aaattttctt tggtgaagaa gattttggaa aagaaaaaag
     4321 tcttgaaaat gcgatagaaa cagtgattcg acactggaat ctgcacgaat aaaaaaatat
     4381 caaaaaaact ttcaataaag ggttgcaaaa atctggaaaa ttaggtatta taactaagtc
     4441 aggttgatac aaacctttcg gaggagtagc gaagtggcta aacgcgacgg actgtaaatc
     4501 cgttccttag ggttcagtgg ttcgaatcca ctctcctcca tttcattggg gtatagccaa
     4561 gcggtaaggc aagggacttt gactccctca tgcgttggtt cgaatccagc taccccagta
     4621 taccacaatc gtaagctctc gttagttcga gagctctttt ttttgctttg ctaccttgtt
     4681 ccttgaagat tctgctgatt taagatagag ttaagttaac tacaagaatt ggagggatcc
     4741 acatgaaatg gaaagaaaaa gtagacgaag cagctgaaaa gttatatgat ttggtcaaat
     4801 cagaaaaata caatattgaa gtgaatattc cgaaaaaagg cggaaaagcg gtccaggtaa
     4861 aatcaaaacg cccaacgaat catacaaaaa aatggatggc taaaaaccgc taataataac
     4921 aaaagatcca taagtcggca ttttcatcga ttttagggtc ttttgttatt ttctaggttg
     4981 aacatatcta aaaaattgtt tctgacaata ggagtaggaa gaacgatgtg tgtctaaatc
     5041 ctctgttgat ggatagaaac ctttatcttt ttcagttgtg aatcaggtat ataccagtta
     5101 taatagaaga aacgaaagga cgggtgtacg ttatgtcgaa tcaattacct gtatatatac
     5161 agattcatga ccaattaaaa aatgaaatcg aacaaggtat atggaaagtc ggagaccgtc
     5221 ttccttcaga aagagaatta gcagtgaaat tcaatgtcag ccgtatgacg ttgagacaag
     5281 caattcaaaa cttggcagat gaaggaatct tagaaagaaa gatcggttcg ggtacatatg
     5341 ttgcgcgaga aaaagtacaa gaaaaaatgt ctggtgcaac aagttttaca gaaattatgg
     5401 aatcgcaaaa tcgagtaccg tctagtcgga caatctctta tttcttgact tcgccaagct
     5461 caagtgaaat ggaaaaacta aacttgagta aagatgacac gatcttgcga atggaacgta
     5521 ttcgtttcgc agatgatgtc cctatttgtt ttgaagttgc cagtgtgcca caaaagctga
     5581 tcgatggcta cagcaaagca gagattactg aatcgttgta tcgcacgcta gaagaaaaag
     5641 gcgggaaaaa gatcggtcca gcgaatcaaa cgattactgc tgtgttggct tctgagaaaa
     5701 ttgctgacta tttagaggta aaacgaggag atgcagttct tcgtttgcgc cagatttctt
     5761 attttgaaga cggtacgccg tttgagtatg tgcgtacgca atacgtagga aatcgttttg
     5821 agttttattt ggaaaaataa aaaacaggtg atccctgatt ccttacttag aaataaaaga
     5881 gaatcagaat cacctgtttt tatatatgat cagttaccag ttgctcgtga taagaaacag
     5941 gaccctcttc aaattggact tgtccgttca gcagctcaat gatggattct ttaaagtggt
     6001 cagcactttt ttcatctaca gcacagatga cgctaacttg atcagtatat tggatttctt
     6061 ttataaaaaa atgttggagt tcaagataat tctgtaattt tcctagttgc ggatacgtga
     6121 tcatcacaga gatctcctgt tgcaaggtac cttctacgat tccaatgtca gacaatgctt
     6181 gagagacagc atgagtgtat gctcgtatta atccgcctgt gccgagtttc gttcctccaa
     6241 aatatcgagt gactactgca gctacattga tcagttgatt ttttttgagg acttccaaca
     6301 tcggtacgcc agccgttcca cttggttctc catcatcgct gcttcgctgg atttcatttt
     6361 tttctccaat gatgaaggcg ctgcagttat ggttcgcttt ccaatgttct ttttttattt
     6421 cttgaatgaa actttttgct tggtcctctg attctattcg tctaagagaa cagataaagc
     6481 gtgatttttt gatctcaatc tcactttgtc cattttcttt tattgtacga tagcgctcga
     6541 tcatcttgtc acctcttttt ttcattttct ttattcagta taaataaagt tctaggttgt
     6601 ttcaacactg taacggttgc gcaatcgctg tagtatgcga taataaagac aaaggtaggt
     6661 ggatctgggg atgcaggaac gaatgaaaaa gtacgatgca attacgcatt atttgaagaa
     6721 caatggcggc tctcaagtaa cgttgacctt tacccaattt gacgaactgc tgtttcccag
     6781 taacggactt cccaaaacag caagggaaag tacagattgg tgggcaaatg attataaaca
     6841 ccctgaaaaa ggtgcctatg gctggataaa tgcaggctat gaagtagttg tcatcaattt
     6901 ggacaaagaa tatgtcgtgt tcaataaatt agtgaaatct agttggctat ttgattaaat
     6961 aaaccgcgtt tagaaaacgt tgacaaattt ctttcttttt atataataga gtaacagacg
     7021 cgaagaaaac gtttgcgtag tttgttttaa aaaggagaga aaagtatggc taaaaaaaca
     7081 atcatgcttg tatgttcggc tggtatgagc acaagtttac tagtaacaaa aatgcaaaaa
     7141 gctgctgaag caaaaggaat cgactcggat attttcgctg tgtccgcttc tgacgcagat
     7201 aacaatcttg caaataaaga tgtagatgta ctgttattag gacctcaagt tcgctttatg
     7261 aaagctgatt ttgaaaaacg tctggaacca aaaggcattc ctttagacgt catcaatatg
     7321 gctgattatg gtatgatgaa tggcgaaaaa gtgttagatc aagcaatcac gctcataggt
     7381 gaataaatag aacagtataa ctatcgaaca agcgatccaa aaaatagatc gcttgttttt
     7441 tcgtatattt ttttagggcg aataatatga atcatttttg gggtagaagg cttctgacga
     7501 gagatattaa agcaatagac tgtgaggagg taaatttacc aaattatgag aagatcgcag
     7561 cagtggaacg tttgggcaac tggattcttt gtcatcgctg tggaatgagg acgtccgtca
     7621 ttgatggaca gcttgcagat tacggttatt tttgtacaca ttgtctatat ttagggcgat
     7681 gcgacactca acaagattta tatttgtttg atcagcctga agcaaaacct cgagaagtcg
     7741 tctttttttg gacaggacag cttactgaaa aacaaacgga aatcgcaaag agaatacttt
     7801 gccattcaga aaaaagacat catcttattt gggctgtaac aggtgcaggg aaaacagaga
     7861 tgctttatcc tattttagtg gaaactttaa aagctggagg aagagtagcg atttgtacac
     7921 cgcgagtcga tgtttgtaat gaattgtttt tacgctatcg ttatgttttt ccagaagaaa
     7981 aaatcacgtt gctccatggg aatacagcaa cggcttatac ctttacttct tttgttatct
     8041 gtacgattca tcagctatac cgtttttatc ggtcctttga tttaatagtg atcgatgaga
     8101 tcgatgcgtt tccttataac ggggatgcag gattagctca tgctgtgcaa acagcgatta
     8161 aaccagacgg acgattcatc tacttaagtg ccacacctga taaaaagtta ctaaaggaaa
     8221 tcaagcagac gtttgacatc cacaaacttg ctttgcgctt tcatcggcgt ttacttcctg
     8281 aacccgtctt ggttttcatg aataattggc gacaaaaatg caagaacaag aagaagataa
     8341 aatctttggt gcggatcatt catcaattaa ttaaagaaaa ccatatcctt ttattttgtc
     8401 caagtatcac gatgatgcat cgtttgaaag ccacacttca agaggctctt ccgagatatg
     8461 agatcacaga tgtttcttca agagacaatc agcgggcgga aaaagtccag aaaatgcgag
     8521 aagcaaaata tgacatactg ttaaccacga tgatccttga acgtggagtc acatttgaaa
     8581 gaatatccgt tatcgtttta ggagcggatc atccggtttt tactaaatct tctttggtac
     8641 aaatcgcagg aagagccgat cgtaaagggc cttatacgaa cagtcaagta tactttttct
     8701 atgaagaaaa aactgcagct attcgaaaag cttgtcagga aatcaaagaa atgaatgaag
     8761 aagggaagaa gatgctgtga ggtgcagttg ctgcagtaaa gatatcgtcc aaaatttaac
     8821 attcagcgag attattggtg tttcgaaata cagattacct cagacttgtt cagtttgtcg
     8881 cgcacaattt catttattgg aaacaagagg ctgttctggc tgtcaaaaac caatccattt
     8941 caatctagag agtacgaaaa agaaagtaaa gtctattccc gtttactgca gtgactgtca
     9001 agaatggaag aagaaatatc cgacctatga ttttcagcac cgtgcctttt ttgtgtacga
     9061 tgaaaatatg aaggcctggc tcaatcaata caagtttatg ggagatatcc gactagcagg
     9121 cacctttgca tataaatgga cgcagataaa aaaagaatac ccgacataca tctattgtcc
     9181 aataccttta tctgaaaaaa ggcgaacaga aagaggattc aatcaagtaa gcgagatgtt
     9241 gaaagcagca agaattcctt ttcagatgct actcaaaaga gagaagcatc tgctggctca
     9301 agcaaaaaac acgcgaaagg aaagattgga gatgcctcaa ccttttgaac ttgcagtcac
     9361 cttttctaag atacaaaata aaaaaatatt gattattgat gatgtctata caacaggaca
     9421 gactcttttc cacgcagcag attgtttgca ggtcgcacag ccgaaaatca tccgaaccat
     9481 ttctttagca agatgaatta gatgtggaaa tttgatagcg atttaatttg caaataacct
     9541 agagttcgat ataatagaat taagaagagg gaaagagtgg tccttctcct tcttgattgt
     9601 ggtagacgaa aggggtaatt tttatgttta gatataatgt acgcggcgaa aatatcgaag
     9661 taactgaagc gattcgcgac tacgttgaga aaaaagtagg caaactagaa cgctatttca
     9721 gtgacgcacc cgatgcaacg gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa
     9781 aagtggaagt aacgatccca ttaccttatc ttgtattacg tgccgaagaa acttctccag
     9841 atttatacgc aagtatcgat ttggttgttg acaaattgga acgccaaatc cgcaaattca
     9901 aaacaaaaat taatcgtaaa tcccgtgaaa cgggcatgaa tactgcagat gctactgctt
     9961 tattcaatga agaggacgaa aacgaaaatg attctgaatt agatatcgta cgtacgaaac
    10021 gcctttcatt gaaaccaatg gatagtgaag aagcagtctt acaaatgaac atgctgggac
    10081 ataacttctt tatttttgaa gatgcagaaa caaatggtac aagtatcgtt taccgccgta
    10141 aagatggaaa atacggactg attgaaacag actgatcagc cttacttaaa taacaacgaa
    10201 aacttgcagc agctactgac agctgccgca agtttttttg agtttcctcc tcttttagat
    10261 gaaatatgaa taaattatga agttcttact ttaatacgct taagatattt caattatcta
    10321 taactaatga taaaatgaaa agtaaagtct acatagtctg gataatacac agaaggaaaa
    10381 ggagattaca caacgcatgg ccaatttgat tcgttcactt atcgaaaacg ataagaaaga
    10441 actaaaacgt ttagatagca ttgcaaaaaa agttgaagca tacgctgacc aaatggcagc
    10501 attaactgat gaacaattac aggcaaaaac tgctgaattc aagggcagat accaaaaagg
    10561 agaaacatta gatcaattac ttccggaagc ttttgcagtc gtccgagaag cagcaaaacg
    10621 tgtattgggg ttatatccac accacgtaca attgatgggt ggaatcgtgc ttcacgatgg
    10681 aaatatccct gaaatgcgta ctggtgaagg taaaaccttg accgcaacga tgccagtata
    10741 tctaaatgct ctgactggcg aaggggtaca cgtagttacc gtcaatgaat atttagcaac
    10801 ccgtgactcg acggaaatgg gcgaacttta taatttctta ggattaacag tggggttgaa
    10861 tatcaactca aaatcttcgg atgaaaaacg cgaggcttat aattgtgata tcacttatag
    10921 tacgaataat gaattaggat ttgactactt gagagacaat atggtcgttt accgccatca
    10981 aatggtacaa cgtccgctga attatgccat tgtcgatgaa gttgactcaa tcttgattga
    11041 tgaagcgaga acgccgctga tcatttcagg gcaagcagaa aaatccacag ctttatatac
    11101 aagagcagac aacttcgtga aacgtttgaa agaagaagaa gattataaaa tcgatgtaca
    11161 atcaaaaaca atcagtttaa ccgaagcagg gatcgaaaaa gcagaagaaa cattcggttt
    11221 ggataactta tacgacattg aaaatactgc attgacccat cacttggatc aagcattgag
    11281 agccaactat atcatgcttt tagatatcga ttatgttgtc caagacggaa aagtactgat
    11341 tgttgaccag ttcactggtc ggatcatgga tggacgccgt tattcagatg gacttcacca
    11401 agcaatcgaa gctaaagaag gcgtagagat cgaagacgaa acgaaaacca tggcgacgat
    11461 cactttccag aactatttcc gtatgtacaa gaaacttgcg ggaatgactg gtacagctaa
    11521 aacagaagaa gaagaattca gagaaattta taacatccaa gtataccaga ttccgacaaa
    11581 tcgtccggtt atccgtgatg atcgtccaga tttgctttac ccaacattac aaagcaagtt
    11641 ccacgctgtc gtgcaagata tcaaagatcg ctaccgcaaa ggtcaacctg tgttagtcgg
    11701 aactgttgcg gttgaaacat ctgagttatt atcagatatg ctgaatcaag aacgtattcc
    11761 tcatgaagtg ctgaatgcga aaaatcactt taaagaagca gagatcatca tgaatgctgg
    11821 tcaaaaaggt gctgtgacga ttgctaccaa catggctggt cggggaacag atatcaagtt
    11881 aggacttggg gtaagagaac ttggtggtct agcagttatc gggacagaac gacatgaatc
    11941 tcgtcgtatc gataaccagc ttcgaggacg tgcaggacgt caaggagacc ctggtatgtc
    12001 acagttctac ttgtcattgg aagatgattt gatgaaacga ttcggttcag aacgaatcaa
    12061 atctttctta gatcggatga agatcggtga ggaagatgct gttatccaaa gcaagatgct
    12121 gacgaaacaa gtagaatctg cacaaaaacg tgtagaagga aataactatg acacacgtaa
    12181 aaacgtctta caatacgatg atgtgatgcg tgaacaacgt gaagtaatct ataaacagcg
    12241 acaagaagta atcatggaag aaaaaagctt atccaagcca ctaatgaaca tggtcaaacg
    12301 gacaatcagt cgtgtagtag atgcgcatac acaattagag aaagaaaatt ggaatttgga
    12361 aagtatcatc gattttgccg gcagtactct tgtccatgaa gatagtatta ctcttgcaga
    12421 tatcgaagga aaaacagctc aggagatcaa agagtatcta aacgaacgag cacaagaagt
    12481 atttaatacc aaagcggctc aactaaatgg tccagagcaa ctgttggaat ttgaaaaagt
    12541 cgtgatcttg cgtgttgtgg actctaaatg gacagaccat attgatgcaa tggatcaatt
    12601 acgtcagtca atcggcttac gtgcttatgg acagaacaat ccattagtcg aatatcaaac
    12661 agaaggctat aagatgtttg aagatatggt aggcgccatc gagtatgaag tcactcgaat
    12721 ctttatgaaa gctgagatcc gtcaaaacgt acagcgtgaa caggtttctc aaggaacagc
    12781 ttctcactca gaagacggag atgccaaaga aaatagtaat actagcgcga aaaaacagcc
    12841 aatccatgtg aacaaggtcg gaagaaatga tccttgtcct tgtggaagcg ggaaaaaata
    12901 taagaactgt catggaaaaa atgcaaacta atttctgaca gcaggattgg tgagacaaat
    12961 tcttttttta agaattcgtc tcaccttctt tctgttattt gctgattctg ttagactaga
    13021 tataatgaaa aaagtatagt gaaagaagga aaaaacatgg aaatatccga aattcgaaat
    13081 ctcctgacag aaatgcagga aaaggtcaca agcttcagga ggtctctttg acttagacca
    13141 gctggaagaa gacattgcgg aagcagaagc aaaaatggct gaacctggtt tttgggatga
    13201 tagcgaagct gctcaaaaag tgatcagtga aaacaatgca aataaagaaa cttatgatca
    13261 attccattct cttgctgaag aactggaaga aatcgaattg atggtggaga tgttgcagga
    13321 agaacctgat gcagccatgc aagaagaagc agaaacacgt atcaatgcgc tagatgaaaa
    13381 aatgaagaca tatgaattat ctatgttgtt agatggtcct tatgatcgaa acaacgccat
    13441 cgttgaattg catccagggg ctggcggaac ggagtcccaa gattggggca gtatgctttt
    13501 acgtatgtat acacgctggg cagagcagca tgggtatcaa gtagagacac tagattatca
    13561 agcaggtgat gaagcaggaa tcaagagtgt gaccctactg atcaaaggac acaacgcatt
    13621 tggttatctg aaatcagaaa aaggtgttca tcgccttgta cgtatctcgc cttttgactc
    13681 agcgaaacga cgtcatactt ctttttgttc ggtagatgtg atgccagagc ttgatgaaac
    13741 gatcgatata gaaatcaatc cagatgattt gaaaatcgat acgtaccgag caagtggtgc
    13801 aggtggtcag cacatcaata aaacagaatc tgctgtacgg atcactcact tgcctacagg
    13861 aacagtagta gctagtcagg cacaacgttc acaattgaaa aaccgtgagc aagcgatggg
    13921 gatgttaaaa gctaagcttt atcaattaga agtggaaaag aaagaacaag aagcagctgc
    13981 acttcgagga gaacaaaaag aaatcggctg gggttcacag atccgttctt atgttttcca
    14041 tccatattct atggtaaaag accatcggac aaacgtagag acaggaaatg tccaagcagt
    14101 tatggacggt gaccttgatt tatttattga cggctattta aaaatgcatc tacaataaga
    14161 acccattgtt aaattgaaat aaaattgtaa gattttgcaa gcatgttgaa acattgccat
    14221 gctataatag ctaaagactg aaaaagatat ggagagaacg ccatgattga aatgaaggat
    14281 gtaatgaaga agtactcaaa tggtacgacc gctatccgca atctctcaat tgtcatcgaa
    14341 caaggagagt ttgtctatgt ggttggtccg tctggagccg gtaaatctac attcatcaaa
    14401 ttgatgtatc gagaagaaaa agcttcaaaa ggaactttga acgtcgcagg tcatgatcta
    14461 atagcaatca aaaaccgcga agttccttat ctacgcagag aaatcggcgt ggtgttccaa
    14521 gactataaat tattaccaag aaaaacagta tatgaaaatg ttgcgtacgc tatgcaagtt
    14581 atcggcagaa aacctcggga tatcaaaaaa cgagtaatgg aagtgctgga ccttgttggt
    14641 ttgaaacaca aagttcgagt ctttcctagc gaattatccg gtggggaaca gcaacgtgtc
    14701 tctattgctc gggcaatagt gaatacgcct aaagtactta tcgcggatga accgacagga
    14761 aatctggatc cagaaaactc atgggaaatc atgaaattat tagatcggat caatgcccaa
    14821 ggaactactg tcgtgatggc tacacataac agtacgatcg taaatacgat tcggcaccga
    14881 gtaattgcta tcgaaaacgg ccgcattatt cgagatcaag cggaagggga atatggatac
    14941 gatgattaga acctttttcc gccatttatt agaaagtatc aagagtttga aacgtaacgg
    15001 ctggatgaca gttgcttcag tcagtgcggt aacgatcaca ttgactttag tcggtgtatt
    15061 catggcagtt atcatgaacg caactaaatt agctcaagat atagaaggaa acgttgatgt
    15121 ctctgtattc gtagatatcg gtacaaaaga cgaagagatg aaaaagctag aaaaagaatt
    15181 gaatgactta gatcatgtta aaaaagttga attttcaagc aaagaacagg aattgaaaaa
    15241 aatccaaaac gaaatgggtg attcctggaa attgtttgaa ggtgacaata acccgttata
    15301 tgatgtgtat gtagtaagtg ctactgatcc ttcttataca aaacaagtag cagaagaagc
    15361 agcagatttg aagaatgttt ctcgttctga ttacggtgga gcttcctcag atcggatttt
    15421 ccaaatcgct ggtgcagttc ggacatgggg attagttgca gcggcattgc tgctgttcgt
    15481 agcgatgttt ctcatttcga acacgattcg gatcacgatt ttgtctagac agcgtgaaat
    15541 tcaaatcatg cgtttagtcg gtgcaaaaaa tggatatatt cgctggccgt ttttccttga
    15601 aggtggctgg atcggtctga tcggtgcgat tcttccgatt ttgatcatca catttggtta
    15661 tgcatggttt ttccaattga tcaatccatc attattacgt tcccattatt cattgattca
    15721 tccacaaaat atcgtttgga aaatcaatct tttaatggtc ggcattggtg tgatcattgg
    15781 ttcacttggc tcgatcattt ctatgagacg tttcttgaaa ttctaatacc acaatataaa
    15841 taaaatgaga aagttggaca gtttcgttcc agctttcttt ttttattggc taggagaata
    15901 gaaggaagcg gcttttttcc ctttacttta aaaaacaact tgggtattct taagttggta
    15961 gaagaagagg tgaagccgtg aaaattatcg ttgacaattt ttttacgatc cttttgatta
    16021 tgaatatttt gctttccttt atcatcgttt ttcgagaaag aaaggaaact gctcaaacat
    16081 gggcatgggt gctcgttttg atgttcattc cagttgtagg atttatttta tatatttttt
    16141 taggaagagg gatttccaaa gagaaaatct ttgatttgaa gatccaaggg aaaatcggta
    16201 agaacctgga aattgaagaa gacaaacagg cattgatgcg agggctttat cctcatccgc
    16261 ctactggaca agtagatgtg aaacaattga tctatatgct cacggtattt gaaagtacgc
    16321 tctatacgac taaaaatgaa atcactttat ttacagatgg tcgtgaaaaa ttcgatgcgc
    16381 tgattgaaga tatcaagcag gcagaagacc atatccactt ccagtattat atttatcgca
    16441 gtgatgcatt aggtgaagaa gttcgagatg cattgacaga ggcggcaaga cgagggggaa
    16501 aagtcagagt ccttcttgat gcatggggtt ccacacaagt ttcttccagc ttttttcaga
    16561 atttgaaaaa agcaggcgga gaagtcgcat ttttctttcc tctatttgtt ccgtatatta
    16621 atcctcggat caattatcgc aatcatcgta aaatcgtagt tattgatggg aaaatcggat
    16681 atacaggtgg gttcaatgtt ggaaatgaat atctaggatt ggtaaagaaa tttggttatt
    16741 ggcgagacaa tcatttgcgt atttacggag aagcggtgta taccttgcaa aaccgttttt
    16801 tgatggactg gaattctcag catacaaaag aagtaggcta ttctcccaaa ttttttccgt
    16861 ccattcactc tactggtgat atagctgttc aaatcgtgac aagcggacca gataccgaac
    16921 atgaacaaat caaaatgact tatttgaaaa tgatttcgtt agccaaacgg gagatattga
    16981 tccaaacgcc ttattacata ccggatggat cgattcatga agcactgaag ttggctcttc
    17041 tttcaggcgt aaaagttcat atccaaatac ctaacaaacc agatcatctt ctcgtttact
    17101 gggcaacgta ttctttcgct gcagagctaa tcgagtatgg agcaaggatc gaaacatatg
    17161 agaatggatt tattcatgca aagacgatga ttatcgatgg tggcattgtt tcagttggct
    17221 cagcaaatat cgatgttcgt tcatttcgct tggactttga ggtcaataca ctggtttatg
    17281 atgaacgaat ggcttcacgt gtaagaaaag ctttttttga agactcgaaa atttctacgc
    17341 atctcacaaa agaaatgtat gaaaaccgag gaataatcat caagatgaaa gaaggattag
    17401 caagattgat ttcgccgctc ctttaaaaca taaaaaggac atgagaacca tcaacagatg
    17461 gagatctcgt gtccttttct aacggggcca tttctgagag tacgtcagaa atggagaaag
    17521 cgtctcgcat gagcgaaatt aactttgggg tatctcttgt tttttgggga aagcaagaaa
    17581 taagctaata tatgctatta aaagagacac atttcaaagc cagtatagca tagaaacttt
    17641 taatgagata gtttttttta caattatgag aatttatttt gttatttaat gattttgatt
    17701 cgttttcatc aagtaatgaa aatgataaaa taaacatact ttaggattaa aggagatttc
    17761 taatgaaaaa acttaaatta ttcttaccaa taataggatt agctattctt ttatcaggct
    17821 gttcaaagtg gattgatcga ggagaatcca ttacggctgt tggctcttct gctttacagc
    17881 ctttagtaga aacagttgct gaaacttacc agacagaaaa tcctggaaaa ttcatcaatg
    17941 tacaaggggg cggaagcgga actggtttgt ctcaagtaca gtcaggagca gtcgacatcg
    18001 gaaactctga tttgtttgcg gaagaaaaat cggggatcga tgcctcagca ttagtcgatc
    18061 atcgagtagc agttgttggg atcactccta ttgtgaacaa ggatattggc gtaaaagaca
    18121 tcagtatgga aaacctgaaa aaactattta caggcgagat caaaaactgg agtgaagtcg
    18181 gtggaaaaga tcagccagta gttatattga accgcgcttc aggaagcgga acccgtagca
    18241 cgtttgaaaa atgggtattg gacggagaaa cagctgttca ggcacaagaa caagattcaa
    18301 gcggaatggt gcgccagatc gttgccgaca cacccggtgc aatcagctat gttgcttttt
    18361 cttatgtttc cgatgatgta gatacgttga atgttaacgg tgtagaaccg acagatgaaa
    18421 atgtgacaac gaacaaatgg acgatttggg catatgagca tatgtacaca agagatcatc
    18481 caaaaaaact gacaaaagaa tttttagact atatcttatc tgatgaagta caagataaca
    18541 tcgttggaga actaggttat atccctgttt ctcatatgaa agtcgaacgt gattggcaag
    18601 gaaatatcgt taaagagtaa tctttacaca aaatttacaa acttagctaa acttttacat
    18661 gttattaaaa ccaaattgat gttcaatttg tacactgagt gagtatgtta aacctgatta
    18721 agggggagtc atctgtggaa gatgtgaaaa aagtattatt aacaaaatca aaacgttcaa
    18781 aaatggaaca gcgtggaaaa ttcatcagtt ttttatgtat cgcgctgatc gtgttggttg
    18841 tattatctat tttttatttt gtagctagta aaggattggc cacctttttt actgataaga
    18901 tcaatgtatt tgattttctg tttggtacag attggaatcc aagccaaatc ggagcaaatg
    18961 ggaaaccaat ggtaggggca ttgcctatga tcacaggttc gtttattgtg acctttttat
    19021 ctgctatcgt tgccacgcca tttgccattg gtgcagcagt attcatgacg gagatctctc
    19081 ctaaaaacgg aacgaagatc ttacagccgg tcatcgagct gcttgtaggt attccttctg
    19141 tcgtttatgg ttttatcggt ttatcagtta tcgtgccttt tgtcagaagt atttttggcg
    19201 ggactgggtt tggtatctta gctggtacat ttgtgttgtt cgttatgatc ttgccgactg
    19261 tcacaacgat gactgttgat gcattaaagg cagtgccacg gcactatcgg gaagcttcat
    19321 tagcgcttgg tgccacaaga tggcaaacaa tctacaaagt cgtgctacga gcagccgtgc
    19381 ccgggatttt aacagcagtc gtttttggta tggctcgtgc gtttggtgaa gccttagcta
    19441 tccaaatggt catcggtaat gcagcattga tgccaacagg tcttactact cctgcttcta
    19501 cattgacgtc catcttaaca atgggaatcg gaaatacaat catgggaaca gttgaaaata
    19561 atgtgttatg gtcattagcg ctgatcttgc tattgatgtc attattcttt aatatcgtga
    19621 tccgtatgat tgggaagaaa ggagagctga aataatgaac gcaaaacgct cagataaaat
    19681 tgctacaggt gttttatata tagtttcggg gatcatcgta ttgattttag cagctttact
    19741 actttatatc ttagttcggg gaataccgca catttcatgg tccttcttga ccgaaccttc
    19801 caaagcctac caagaaggcg gtggaatcgg gatccagcta tttaactcga tttatttgct
    19861 tttgatcacg atgatcatca gttttcctat ttctttaggt gcgggtatct atctttcaga
    19921 atatgctgga aaaaactggc taacagatgt gattcgcacg tcgattgaaa tcttgagctc
    19981 gttgccttct gtcgttgtcg gtttattcgg tttcttggtt ttcgttattc aattccagta
    20041 tggtttctcg attatttctg gtgcattggc tttgactgta ttcaacttgc ctcttttgac
    20101 tagaacagtt gaggagtctt tacaagcggt ccattacaca caacgagaag caggattggc
    20161 cttaggtttg tcacgctggg aaacagtgat aaaagtggtg gttccagaag cgacaccagg
    20221 gattttgact ggtgtgatcc taagttctgg aagaattttt ggtgaagcag ctgcattgat
    20281 ctatacggct ggacaaagtg cacctgcgtt agattttacg aactggaatc cattaagtgt
    20341 ttcaagcccg atcagcattt tccgtcaagc tgaaacatta gctgtccata tttggaagat
    20401 caatacagaa ggcacgatgc ctgatggtgt ttctgtttcg gctggcgctt ctgccgtgtt
    20461 gattattgct gttttactgt tcaacttcgg cgctcgtgcg attggcaaac gattataccg
    20521 aaaaatgact tcagcctaag gagaagaagc aaaatgaaaa aatataactg gaatgaaaca
    20581 aatgtcatca ccatgccaaa agagaaagaa gtagcactat atacggatga tctacatgtc
    20641 tggtatggcg acaatgaagc aatcaaagga gtggatctgg aatttgaaaa aaataagatc
    20701 actgcactga ttggtccttc cggctgcgga aaatctacgt atcttcgttc gttgaatcga
    20761 atgaatgatg ggatcgctaa tacgaaaatc actgggaaaa tcatgtatca aggcgtagat
    20821 attaatgcgc ctcaagtgga tgtttatgag atgcgcaaac ggattggcat ggtttttcaa
    20881 cgtcctaatc cgttcagcaa gtcgatttat gacaatatta catttgcttt gaaacagcac
    20941 ggcgaaaaaa acaaaaagaa attagatgaa atcgttgaaa caagcttgaa acaagctgcc
    21001 ttgtgggacc aagtaaaaga cagcttggac aaaagtgcct tggctttatc tggcgggcaa
    21061 cagcaacgtt tatgtattgc tcgtgcgatc gcgatgaaac ctgatatctt gctgctagac
    21121 gagccggcaa gtgctttgga ccctatttcg acaggaacgg ttgaagaaac acttgtaaac
    21181 ttgaaagaag actatacgat catcatcgtg acgcataaca tgcaacaagc agctcgtatc
    21241 agcgactata ctgccttttt ctatttagga aaagtaatgg aatatgacaa aactaacaag
    21301 atatttacca gaccaaaaat tcaggcaacc gaagattatg tgtccggtca ttttggttaa
    21361 gacggaggcc tcaacatgac aaaagagatt atttcatcta aagatcttca tctgtattat
    21421 ggaaagaaag aagcactaaa agggatcgat ctaagcttca atcaagggga aatcactgcg
    21481 atgatcggtc cttctggttg cggaaaatcc acttatctgc gttctttgaa ccggatgaat
    21541 gacctgattc cgaatgtaac gatcaccgga agtgttttat ataaagacaa agacatctat
    21601 ggtccaaaaa cagatgttgt tgaactaaga aaagaaatcg gcatggtatt ccagcagcca
    21661 aacccatttc ctttttctat ctatgaaaat gtcatctatg gattgaaatt aaaaggggaa
    21721 aaagataaaa aagtccttga tcaagtagtt gaagaaagcc tgaaggcagc gtctgtttgg
    21781 gatgatgtga aagacaaatt gcataaaagt gctttatctt tatccggtgg gcagcagcag
    21841 cgtgtatgta tcgcacgtgt tttggcagtt aatccggaaa tcatcttatt ggatgaacca
    21901 acaagtgcgc ttgatcctgt ttctactggg aaaatcgaaa gtatgctgtt agaattaaga
    21961 gagcggtata cgatgatcat cgtgacccat aatatgtctc aagcttcacg tatttcagat
    22021 aagacggcat tctttttaga tggtcacttg atcgaataca atgatacgaa gaagatattc
    22081 atgaatccag aaaaacaaga gacagaagat tatatttcag gtcgatttgg ataaggagga
    22141 aacggaatgc tacgtacaca atttgaagaa gaattgctga atctccataa tcagttctac
    22201 gaaatgggga tgatggtgag cagcgccgtg cacaagtcag ttcgtgcata catcaaacac
    22261 gataaaatct tagcccaaga agttatcgaa aacgatataa atatcaataa catggaaaca
    22321 cgcttggaga agaaaagttt tgaaatgatc gcattgcaac agccagttac aactgatttg
    22381 cgtatgatca ttacggtcat gaaagctagc tcggatttag aacgtatggc cgatcatgcg
    22441 gtgtctgttg ctaaatccac gattcgcgta aaagggcaga cgagaatacc ggaaatcgaa
    22501 aaagagatct ccgatatgtc cgattatgtg aaaaaaatgg tggacaacgt cctagttgct
    22561 tatgtcaaaa cagacgaaaa agacgcacgt acgatcgcca atatggatca aagagtcaat
    22621 gactatttca atcgaatcta taatgcaaca atcaaaaata tgcaggaaaa tcctgagaca
    22681 gtcatcagtg gaacagacta cttgaatgtt gccagttatc tagaacggat cggagactat
    22741 gtgacaaaca tctgtgaatg gatcgtctac ttggctacag ggaaaatcac tgagttaaat
    22801 acgaaccaca atgagatttt ctaaactgaa gctgtgatta tgccgtttgt ttaggaaaag
    22861 aggttgtgaa atcagcggtt gtgaaaaagc tgttctgcat caagtaataa gaacagtcaa
    22921 acaaaaaata gctcctcata tttttcgttt ggctggactt attaccgcag atgcaagctt
    22981 ttgaacaccg tttattcggg aaagggtttg tgacaaaaca tgtcacaaac ccttttcatc
    23041 atttcataga aaggataaag aatgcaaaaa aaaattagca tcatcactat attttttatt
    23101 tgtgtgctta cttcatgggt tattcagcat caagccgctt tatatgaagt acctgtcatc
    23161 gagatagaaa aagtacgaat aaaagaggat catcaattga ttacaggaaa actgatgaac
    23221 acggatcaaa aaggagaatc gatttattta tcggttcctt atcaaaaaaa tcaaatagaa
    23281 acagcaaata taaaagcgag acaaatgtat ctagtccaaa tgcatggaga tgaatggcag
    23341 ctagtagcaa aaaaaaatga tggctggctt ttcttcttca caagtatctt cattggcgcc
    23401 atgttgctta ttggtggaaa acagggtcta tttgctttag gaagtctcat catcaatatc
    23461 gttttacttt tacttttgtt gctcatcttt actaaaacag aagggatttc tctattaaat
    23521 atatctatcc tgttcgtcgt tatagggatg attattagca tattggcttt agatggatgg
    23581 aatagaagca gtataatcaa aatttcagct gcagttacga gtgttttttt agcatttttt
    23641 atttgtcttt tgacaatgaa tcattggaaa gaccaaggac tgcgctatga ggaactgaat
    23701 tatctgacac gaccgtatcg ttctgttttt ctttctagcg tactgattgg aacagctgga
    23761 ggaacactcg ataccgttat cacagtcatt gcgacattag aagaattgac taagcgacaa
    23821 ccagaaataa cagcgaaaca gttatggctt tcaggaaggc aagtgggtcg agatgtgatt
    23881 ggctcgatga ccaatatcct tttgttcgtc tatatcagtg ggtcagttcc atcgtttctt
    23941 ttatatttag gaaatcaatg gtcgttcaaa gaaacgatag aacagcattt atcattggaa
    24001 tttttacgcg tcattgctgg cagcttagga atagtattat cgatccctat ctcggtcctc
    24061 ttttttctga ctgtaaggag gctgaaacga tgaatgtact tattatactt gttgggattt
    24121 tagcaatcag cgtgctactt attggcggta cgcaaggtat gtatattctt ttaggcttat
    24181 tcatcaattt agggatcttt ttcctgttgt tattcggtta tcatcagaag tggccgatac
    24241 tggcattgtc ggtcatagga tttttattga ttgctgtggt tatcttattt tttatcaacg
    24301 gttataatct aaaaatgcgt gcagcttttg tgagtatact gatcttttta ttttgtttcc
    24361 tactattgct tcctatcact gattttttag caatccaagg ttttacatcg gtagaactag
    24421 aagaattatc tggcttagat aagactttag cgattgattt tagattactt acgagatcgt
    24481 tgcttctgat tagtcttagt ggtgctgttt tagatgcgag tgtagcaatt tctagtggga
    24541 cattcgaagt atatcaggca aatccgcaat tatcttttta ccaattgcgc cattctagtt
    24601 tcgctattgc taaaaaaata ttggcgtcaa cagtaatgac acttcttttt gcattcatgg
    24661 gaagttcttt agcgttgatc ctctggttta ttgatttaga cattcctttt cagcaagtga
    24721 tcaatgaaaa atcatttgtt ctagaatata cgatggctat tcttaccaca ttgtccgcac
    24781 tacttgttct tcctttaacc tgcgtgacta cagcatatct ctttacaaaa aagaaagaac
    24841 aactcaagat ggagtaaaag ttacaactta agtcctatga catttttact gaatcagtgc
    24901 ataatatgga tgtaaggaaa agcttgcaaa caattttgct taaggaggca atttccatga
    24961 aagaaagaga acgtatttta gatttagtga aaaaaggaat cctttcgact gaagaaggct
    25021 tagatttatt agaaagcatg gcaactgaaa aagacgaaaa gcaaatcaaa aaagaagcag
    25081 acaaggtaac tgctagtcat aaagaaaaag atcaggcaag tcaattgatc gataaacttg
    25141 aaaacggcga agaagaaatt tctgagccag ttgatccaaa ggaaagagaa agacaagatc
    25201 aagaaaactt agaaaagatc ttagatgaac tagcaactga agcgaataaa acttcggcgc
    25261 gtctagatga agtaaatgct caattcgctg acaataaggc agcacgcaat gagaaacagg
    25321 aagcattgat gcagctgaat acaaaagaag aattaggcga gttgacagaa gaagaattag
    25381 cacagcgtca gacgttagaa gcagaaatca aagaattaga agctagtggc gatacactgt
    25441 tagaagaaca attgaaatta gaagcagaat taaaagatat ccgtaagaat caatggtctg
    25501 agaaaaaaga aacgtttact gataagtttg aattgccaga tgattggaaa gatcaagcaa
    25561 cagatacact gaatcaagta ggcgaaaaaa tgtcagaagc tggatcacag ttaggcaaat
    25621 tcttgaagaa aacattccaa actgtttcag aaacagtgaa tgacaacatg gaatggaaag
    25681 atgtcagctt acgtgtccct gggattgcga caacgaaatt tgagcatgaa ttttactatg
    25741 aagctcctgc agcaagtatc cttgatatca aggcagcaaa cggaaacgtg acgttaaaaa
    25801 cgtgggacag caacgatgtg aaagttgaag ctaagatcaa actttacgga aaaatgggtg
    25861 ctgaaccatt tgaagcattc tctgaacgga gccagattga ggttaatgaa gatcatatct
    25921 ccttccaaat tccaaataaa cgtgtgcgtg cagaccttgt tttctactta cctaaacgag
    25981 tatacgacca cgcagctatt aaacttctaa atggcaacat catgattgaa acattggaag
    26041 ctaaagatat ttatacaaaa tctacgaatg gtaacatcat cgtggaccaa ttaactgcaa
    26101 cgatgctgga agtagaaggt gtaaacggca atatcgatat tcgaaacggg aacatcttag
    26161 attctattat cgaaacagta aatggtacag tgacatttgg tgcgacagca gaaaaccttt
    26221 ctgtgtcttt ggtaaatggt gatgtacgtc ttacgattaa agaagataat ttgaaaaaag
    26281 tagaagcaag ttcagtgaac ggaaatgtca aagtcgcttt accagatggc atcggtttgg
    26341 aaggacatgc taaaacaagt cttggaagta tcaacagccg tctgtccaat tacgaagtag
    26401 ttcgtgagaa aaaagaacgg acaaaccaaa tgttgcaatt ccgtcgtgtt tcagatggtg
    26461 aaatcgcgca agtgcaactt tcaacgacaa caggaagtat ctatttaaaa gatacagata
    26521 aataaagagg ttgtgaaaga gatgttcagc cttgagcaat aagaagcgat tttgtaaaat
    26581 agcttcccct attttacaaa attgtgcctt attgccgata gtctatctct tgaacaccgt
    26641 ttaccaagag attatgaacc tgccaattat cgccgagtca caaggaataa tttcagaaaa
    26701 agctcgtcac gttttatgaa tatggtaatt tgtgaccgag aattttgcag aaagacaccg
    26761 attaagaaga aggttgtcac aacgattttc ttcatttaaa atagtagaac agaggtgaga
    26821 catgatgaaa aaaaagttga caaaatctaa taaaaatgtt gttttgacag ggactttagc
    26881 aggaatagga gaatacatcg ggattgatcc gactgttatc cgtgtgcttt atgtattcct
    26941 gagcttagtt gcttttggaa gtccaattat tttatacatt ttattagctt tgattatccc
    27001 atctgcgcgt tctgcacgaa caaactatgg acataacaat gcatattatg aaaaaaacaa
    27061 ttatcgtgaa caaactcgtg aacaaacaaa aaaacgcaaa gaagcggaaa aaatcgatga
    27121 tgacgaatgg agtgactttt aatgtcgtac tttcaacgta ttttagttaa tacgttaaca
    27181 ttcatatcat tggctgttct ttttcctgcg atggtccatg tgagcagtat ttggacggcc
    27241 gttcttgcca gcttcgtatt gtctgtgttg aatatgtttg tcaaaccgat tttgacgata
    27301 ctgtccctgc cctttacatt agtcacattg ggattgttta cgtttgttat caatgcagcg
    27361 attcttaaaa tgacctcctt ttttgtggga gcagaacatt ttagtttttc ttcattcggt
    27421 gcagcgttgt tagtagctat cttgatgtcg cttgtcaatg taattgtcag cgaacataac
    27481 agtagaaaat aaaagaaagc tgtgccgaac tatcggcgca gtttttttat ttagaatcag
    27541 gaatgcgttt tctattacat tggtaattaa ataaaaacgt tttttttaat tggtagtact
    27601 tttggctaga caatgataaa atgatagaga acactctaat agaaatgagg tagcatgaat
    27661 gtcagaagtt gtaaaagtta gccaattagt gaaaaaatta tctttggaaa tcgtgacagg
    27721 cgacgagaaa agcttagacc gtgtcatcgt aactggggac atctcacgcc caggactaga
    27781 gttgactggt tattttaatt attattccca taatcgttta cagctatttg gcagtaaaga
    27841 aatcagtttt gcggaacgga tgatcccaga agagcgtttg atcatcatga gaagattatg
    27901 tagtgaagat atgcccgcat ttattatttc aagaggatta ccagctccag aagaaatgat
    27961 ccaggcagca aatgaaaatg ggatagctgt actgcgttct cccatctcaa cttctcgttt
    28021 attaggagaa ttatccagtt atttagatgg tcgccttgcc cctcgaacaa gtgtccacgg
    28081 tgttttagtg gatgtttacg gattaggtgt actgattcaa ggtgacagtg ggataggaaa
    28141 aagtgaaaca gcgttggagt tgatcaaacg cggccatcga ttgatcgcag acgatcgagt
    28201 agatgtttat cagcaagatg aattaacggt gatcggagaa ccgcctaaaa tcctggaaca
    28261 tctgattgaa atccgaggaa tcgggatcat tgatgtaatg aatctttttg gtgcgagtgc
    28321 ggtacgtggc tctatgcaag tccagttggc tgtttatctg gaagcatggg caaaagataa
    28381 gaaatacgac cgtctgggct ctgaagacac gaccgttgaa atcgcggaag tgggcattcc
    28441 acaaataaaa atccctgtca aaacaggacg aaacgttgca atcatcattg aagtagccgc
    28501 gatgaatttc cgtgcacgta caatgggctt tgacgcaacg aaaacatttg aagaaagatt
    28561 aagtcgcttg attgaagaaa actcaggcaa cgactagcaa ggagtgacaa tatgttagca
    28621 caaatcaatc gagttgcttt tgagcttgta gggattccta tctactggta tgcattgatc
    28681 atcgtatcag gtatcattat cgctatgtgg cttagcagca gagaggctgt tcgggtagga
    28741 ttaaaagcag atgatgtgac agattttatg ttgtggggat tgcctatctc cattattggc
    28801 gctcgcttat attatgtttt atttgatctt ccccagtata tagctgatcc aatccaaata
    28861 ttcaatatcc gttcaggagg cttagctatt tatggcggac tgattgcagg cgcgatcacg
    28921 ctgtattttt ttactaaata tcattttatt tctttgtgga cttttttaga tatcgctgca
    28981 ccaagtgtat tattagcaca ggcaatcggt cgttggggaa atttcatgaa ccacgaagca
    29041 tatggaccag acacgacgcg aagcttctta gaaagtctgc atttaccgca attcatcatt
    29101 gataatatgt atatcgaagg gatctatcgt caaccaacat ttctttatga atcactttgg
    29161 agtttgattg gatttatttt gcttttgttt ttacgaaaga aaccacacct tttgaaaaaa
    29221 ggcgaagtcc ttttatgtta tctaatgtgg tatagtttcg ggcgtttctt tattgaagga
    29281 ttacgtacag acagtcttta ctttttaggt gtgatccgta tttctcaatt attatctgct
    29341 gtgttatttg tcggtacatt gattctattt atttggcgca gaaaaaaagg aaatttaccg
    29401 gattatgacc gctcattagg aaaaaatcaa caaattatct gatttttaga gcgttaaaaa
    29461 tgaaaaaaat ttcaggagtg gtaaaatgaa ttatagagta gcggttttag gaccaggctc
    29521 ttggggtact gctttggcac aagtcctcgc cgaaaacgga catgacgttc ggatttgggg
    29581 acatcatgct tcacaagtag aagaaatcaa cacccaacac acgaatcaac gttatttacc
    29641 agatcattat ctacccgatt ccatccaagc attcaccaat atggaagatg cagtaaaaga
    29701 cgcagatgcg gtgctattcg tcattccaac gaaagcaata cgttctgttg caaaagaact
    29761 agtgcctaaa ttgaatacaa agccagtgat catccatgca agtaaaggat tagaacaggg
    29821 aacacataaa aggatctctg acatcttgtt agaggaaatc ccagcagaaa aaagaaaagc
    29881 tgttgttgtt ctttctggac caagccatgc agaagaagta gcaaaacatg acatcactac
    29941 gatcacagct gcaagtacag atgcaaaagc agcaaaatat gtacaagagc tgttcatgaa
    30001 taattatttt cggatctata ccaatcctga tgtgatcggt gtagagatgg gggcagcttt
    30061 gaaaaatatt attgctattg gtgctggcgc tattcacggc ttagggtttg gcgataatgc
    30121 aaaggcagca atcatgacgc gcggattagc tgagatcagc cgtttaggtg tagcaatggg
    30181 tgccaacccg ctgaccttta tcggattaag cggaataggc gatctagtcg ttacttgcac
    30241 aagtgttcat tctaggaact ggcgcgcagg caacttgtta ggacaagggc agcccctaga
    30301 agaggtgcta gccaatatgg gaatggtcgt tgaaggtgtg aatactaccc aagcagcgat
    30361 ggaactagcc caaatgatgg aaatcgaaat gcccatcact caaacaatct atgaagtgct
    30421 gtatgaacaa aaagaaatca aaacagccgc aaaagaaatc atgttacgtg atggaaaaaa
    30481 agaaaatgaa ttctcattaa caattttttg aaggagcgaa tgtatatgaa agttaaaaaa
    30541 gcagttattc cagcagcagg attaggaaca agatttttac cagcaacaaa agctatggca
    30601 aaggaaatgt tgccaattgt tgataaacca acaatccagt tcatcgttga agaagcgttg
    30661 aaatcaggta tcgaagacat cttgatcgtt acaggaaaag ctaaacgacc aatcgaagat
    30721 cactttgatt caaatattga attagaaaca aacctaagtg aaaaaggaaa gaccgaatta
    30781 ttgaaattag tagaagaaac gacagatgtc aacttgcatt tcatccgtca atctcatcca
    30841 aagggtttag gacatgccgt tcttcaagca agagccttta ttggaaatga accatttgtc
    30901 gttatgctag gcgatgatat aatggaagac gaagtaccat tgacacagca attgatcgat
    30961 gactatgagc gtacacacgc ttctacgatt gccgttatgc aagttcctca cgatgaaact
    31021 tcaaaatacg gaatcatcaa cccaggggaa gtactggaag atgggttata caatgtcaaa
    31081 aactttgttg aaaaaccaga tccaagcaaa gcaccaagtg atttagctat tattgggcgt
    31141 tacttattga ctccagaaat ctttgatgta ttatcagaac aacaaccagg tgctggaaat
    31201 gagatccaac taactgacgc aatcgatacg ttgaataaaa cacaacgcgt atttgcccgt
    31261 aaattcacag gtaaacgtta tgacgttggt gacaaatttg gttttatgaa aacaagtatt
    31321 gaatatggtc tgacacatcc agaagtaggg gcacctttgc gtgaatacat catgtcttta
    31381 ggtaaaacat tagaagcaga aggaagcaag atcaatcata atccaaaagg aataacagaa
    31441 atcaaagaag aaaagaaaaa ataatctttt tttctaacga gcttcagcgg ctaattgaat
    31501 aaaaagtagt tgaagctcgt ttttatttgt ttaaaaaaca cgaaaatgct atccttatag
    31561 aaaagagaga caagaaggga gtttgatcat gtcaggagga gaaattgcag gattgatcgc
    31621 agcaatcgcc tttgcgatac ttgtcgtttt catcgttcgc gtattgttgc aagtttccaa
    31681 aactttagaa aaagtagacc agactgtcgc agaagcaaat acgacaattg agatcgtcac
    31741 acaagacgta gatcttttat ctagacaagt agaaggcttg ctagtcaaaa gtaatgagct
    31801 gctcttggat atcaatggaa aagtcgcaac gatcgatcca ttgttcacag cagttgctga
    31861 tttaagtgaa agtgtatcgg aacttaatca ttctagtaaa aacatcgtga cgaaagtcgg
    31921 cggaatcgga aaaacgacag ctaaagcgac tgttgccgga aaagtcggtg gaacagcgat
    31981 gaaatttttt aaaaacaaaa aacatactga aacgacagga ggaaaataag aatggctaaa
    32041 aaaggtggat ttttattagg tgcagtagtt ggaggtacag ccgcagcaat cgccgcatta
    32101 ttgttagcac ccaaatctgg taaagaactt cgggatgaat tggctgctca agcagatgat
    32161 ttgatggaca tggcttcaga ttacacagat atggcaaaag aaaaatcatc tgagttaaca
    32221 ggtattgcaa aagaaaaagc gcaaggtctt tctcaacaag caggggatct agcaggcaat
    32281 gttaagcaga aggtaagtga atcagcagag gaagcaggaa gtgaatcaga tgatatcttg
    32341 ttaaacctca aagaacaatc agctgattta tctaatcgtt tcaaaaaaac agcagaagat
    32401 ctgaaaaagc cagcagacga attaggtagt attgctaaag atacttcaga agatatcatg
    32461 atcgatgtaa aagatgctgc agataaagca ggagagacgg tcaatgaagg aatgtcagaa
    32521 gcaaaaccag ttgcagatga cacaaaagaa atgttgaaaa tggcaaaaga agatgcaaaa
    32581 gaagctaaaa aagaaatgaa agatacaatg acagattcga ctaccaatca ctaagattac
    32641 tcatttctag aataaaaaag gtgagagcgg accagctctc acctttttta ttttcattac
    32701 tctaaaacaa gtaattcttt tggtgtagtc gtgaatggca cacaaccatc acttgtcaca
    32761 tacacacaat cttcgatacg tacccctact ttttcaggaa tatagattcc tggttcaaga
    32821 gagaagcaca tcccttcttc aatcactaag tcgtttcctt ctacaagaga agggaattcg
    32881 tggacggttg ttccgattcc gtgacctaaa cggtgattga aatattcgcc gtagccatag
    32941 ctgttgatca cgtttcgtgc gatttgatca agttcacctg ctgtcacacc tgggcgaact
    33001 gcctcttgtg cggcaagctg tgcttcaaga gtgatgttat agattttttc ttggaactca
    33061 gttggttttt gataagcaac tgtacgagta gcatcactgc aatagccatt ccaaataacg
    33121 ccaagatcga ataacactag ttcatttggt gaaaccttcg tgcttcctgg tgtaccatga
    33181 gggcttgcag catttgctcc tgcaaggact aatgtgtcga aagacatttg tgaaacacct
    33241 tgttttttta attggtattc gatttctgcg ataattgctt gttcagttac gccttctttt
    33301 actgttttga agccaatttc aaaggcaaca tcggcccatt taccagcttc gatcagtttg
    33361 tctttttctt ctaccgtttt gatcagttgc agacgctgga taatagaagt tagatcggtg
    33421 taagaatctg tacctgtcaa gatatcagag atagcatcga agcgatcgac agtcagagca
    33481 ttcttttcaa tacctacatt accaggttgc ccatagcgtg cgcgaagctc ttttccgatg
    33541 atctcccaag gattttcgct gtctaagtag ccacgtacat cgtacgccca gctgctgttt
    33601 tgagcatctt caacttccag agcaggagtg aaaaggaaag gatcttgttc cagagggata
    33661 aaaagagcta gtacacgctc gtgaggatca ctttcatatc cggaaaagta agcgatgtgg
    33721 ccagggtcgc tgatataagc caattctact tggtgttgtg ccatccattg acgtagttca
    33781 ttgattttta cgttattcat ttggcaacct actttctaaa ttaattttgt attcaataat
    33841 tgtaccactg attgattaaa agaccaacgt tcttaaaact gaaaaaagta aaaattttca
    33901 tgaaaacaga gataaaacgg ttgcaattgt tgagattatt tgatatccta ttttagaaat
    33961 gtaagacgta ttttcagaaa acatataaaa tatgaatagg agaacacaaa tggaaaagca
    34021 aacaatcact atctatgatg tagcgagaga ggcaaatgtt tcgatggcta ctgtttcacg
    34081 tgtcgtaaat ggcaatccaa acgtcaaacc agcaacaaga aaaaaagtct tggaagttat
    34141 cgatcgcttg gattatcgtc caaatgcagt cgcacgtggc ttggcaagta agaaaacaac
    34201 aacagttggg gtaatcattc ctgatgtcag caatatgttc tttgcctctt tagcacgtgg
    34261 tatcgacgat gtggcaacaa tgtacaaata caatatcatc ttagcaaact cagatggcaa
    34321 cgatcaaaaa gaagtcaatg tattgaataa tttattggct aagcaagtgg acggcgtgat
    34381 ctttatgggt caccatatca cagacgaaat ccgtggagaa ttttcacgtt caaaaacgcc
    34441 tgttgtacta gctggttcca ttgatccaga tgaacaagta ggtagcgtaa acattgatta
    34501 tgtgtcagca acaaaagatg cagtaaataa attagcaaaa agcggcaata aaaaaatcgc
    34561 ttttgtcagc ggtgcgctga ttgatcctat caatggtcaa aaccgtctaa aaggctataa
    34621 agaagcatta agcgaaaaca atctaccata tagcgaagga ttgatttttg aggcacaata
    34681 caactttaaa gatggtctgt ctctagttga ccggatccat aatagcggtg caacagctgt
    34741 ctatgtttca gacgatgaat tagccattgg tatcttggat ggtttattag accgcggcgt
    34801 aaaagtacca gaagaattcg aaatcatcac aagcaacaat tctttactga cagaagtagc
    34861 tcgtcctcgt ttgacaagta tcacacaacc attatacgat ttaggagcgg tatccatgcg
    34921 cctattgacg aaaatgatga ataaagaaga agtcgaagaa aaaacgatta tcttgcctta
    34981 tggaatcgaa gaaaaaggat caactaaata ataaaagatc aatcatttaa aggttgttcc
    35041 aaaagtggtc aacttctgga acaacgttta tacgagaaag ggggttatga caaaattttg
    35101 tcataacccc tttttttttg tgactttaaa aaaagagaaa atggcggaaa caaaccttac
    35161 gtccatcgta tacgacacaa tctgtgcgta gatgctacat tttgttcact actatcaaaa
    35221 ttactttaaa atgaaaacgt gataaaaaag aaagtagaaa agtagataag taactctaaa
    35281 aaatccaaaa aaatccaggc tcgattgcgt acttatctta aaggagaaac aatccatcat
    35341 atataacccg aaaggagact tctatttgcc taagaaaaga cgaaagacca tagtcatcat
    35401 tttgaccatt cttactatag gaatcggagg gaaattttac atggacaaaa gagaaatgca
    35461 aagacagaaa gatttactcg cagtagaaaa acagtccgtc aaagttctga aaaatacctt
    35521 tgcggatatc aaggaagtga agattgaaaa atctgctcga aatgaaatga cgtgttcata
    35581 ccggatagtt attctaatga ctaataaaca agatcaatcg atttattttt cttatagttt
    35641 ttggaaagaa agaaatgaga taggaagtta cggaatagtt gatgaaaaaa agcaaaaaga
    35701 aggaaatacg ctcaataaag ttaaagtaac ttactctaat ggaaatgagg aaagtattta
    35761 atgattactg acaaacaata tagtgaatta agtgatgctg tttactggct agatcctaaa
    35821 catagagact atgtacctga aatgcaagaa aatttaagtt ttaaaattaa cggcactatg
    35881 tataaaatcc taaaaatcaa aaactccttc gacggcatgc aggcgatggc tgtagcgcca
    35941 atcgtccata gcaaattgga gaaaaatttc aaaaataaaa aaattcctgc aaactttcgc
    36001 gtacttaaat aatgaaggtg tcaatactta cataaaaaga aaggaggcac gttcttgtca
    36061 aggaaaataa gaaaactcag cttagccatt ttattaatcg tcatattagg gatcggaggg
    36121 aaagtctata tggacaaaag agaagcacaa aggcagaaag atttactcgc agtagaaaaa
    36181 cagtcagtca aagttctgaa aaataccttt gcggatatca gggaagtgaa ggtagaagaa
    36241 tttaaaaaaa accctgttac cggaagttat ggtgcacttg tgacaatgac aaataatgaa
    36301 gggaaatctg tttattttga ttatagtttt tggaaggaga gaaatgaact tggtggtttt
    36361 ggcattgaga acagagcggt acaaaagaca ggagtcacta taaaaagagt aaaagtaatt
    36421 ttttctaacg gacaggagga gttagtatga caataaacga taagcattac aatgatatta
    36481 gtgagaaggt ttattggcta gatcccaaat atccccgcta caatgaggga tacaaaaaga
    36541 actctgttaa agaatttgct ggtatggaat ttcaaatcct acaaatcaaa gactcattgg
    36601 acggcatgca ggcgatgtct gtagcgccaa tcaagaacgg taaagtggat ctttctcaag
    36661 tagtgattgc ttttgcagga acgaacttaa gtgattggaa agatttggaa acggatgcaa
    36721 gaagtatcat gaatctctac gggaatagac caggagcaag tttttctgaa aaagcaacaa
    36781 caaacaagat tttatccgtt agtggattga aaacagcggg gcaaatcaat tcagcgattg
    36841 catttgctaa tgaagtaaaa aaggaatatg gagaagctgc tatttctact accggccatt
    36901 cattaggtgg attcttagca ttatatgtag cagcagagaa acaatggaaa aatgtcggct
    36961 tcaacgggcc ggacccgtat gatctcttat caccagaagc aaaaaaatgg gtggaagaaa
    37021 atcccggtat gctcaccaat taccgaaatc acgccgattt tatcggtaat tttggtggta
    37081 atggcacagg tgctgaagtt cggatcagta tggaaacagc attcttgaat ctgcttgctt
    37141 cccacagttt aacctcttgg aagtttgatg aaaatggaaa gctgattatt cctgaaaatg
    37201 aaaacaatgt taaagctcga aaacaacaga aagaaaacca agcgacccag ttgttttcct
    37261 atcagttgca agaactgaac aacatacgta aaaaactacg attaagtggc ggccagctga
    37321 cagttaatga acaaatttac ttagatgaca cacaagctag gttagtagtg gaaaagttat
    37381 cggcaaaaat gaaaagcgct atggaagaag ttatccgcat caatcaaaga ggaatttttg
    37441 agctagagaa aaaatggcaa gaaggcttgc ggcaagcacg tgttgtagcc ccttcgttga
    37501 ctgaacagga aatcatagaa gcattagcta gtgtgggcgc cacaaaagaa aacttagtcg
    37561 attctgcgaa agaagtctat ctgctacgaa tcaataaggc aagacgtatg ggggaggcct
    37621 ttgatacatt ggcgaaggag atccaagaca aaatcaatga aatcgtggca cgagatcgag
    37681 aattagcaca gcaattcaat taaaggagaa gtagatgaaa ctagaagaat tggaaagaga
    37741 ttatcgaagt gaacgaagac aattagaagc tcaagaagat gaattgatcc actttaagaa
    37801 tcaaggatta cgattgatgg agcaagagga gcagcgactg catcatgtat taaagaactt
    37861 agctttagat aatgagcctc tgtttcaagc aagacgaagt tattcgaatt atcaggagca
    37921 ttatcaacaa gccctacaag tagaacgacg aaaactctat cagcagcaag atgaactaga
    37981 acgttcctat cgtcaaaaaa tcagacaaat aactatggag aaatcatctt atgaatgaat
    38041 ttttaatgca attactaaaa gaattagaga aaaatctaca tcgatcaaat gtacgttcag
    38101 ttggtatggg gatatctcag caaatttggg cagaaaaacg attgacagat caaaactacc
    38161 aaatgactgc agaagaagct gctcaagaat tttctaaccg acatgtacac ttgaaaggat
    38221 cagtaaaagg gcaatttgca gaaaaactaa ctgaattatt ccaaagacaa gaaaagaaat
    38281 taaaacagtt tcgttagtaa agttatatag aaaaattttg tgaaaat
//
LOCUS       DAFEIE010000023        37754 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFEIE010000023
VERSION     DAFEIE010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.023"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(69..689)
                     /locus_tag="LP345_001286"
     CDS             complement(69..689)
                     /locus_tag="LP345_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBL1760076.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(881..1177)
                     /locus_tag="LP345_001287"
     CDS             complement(881..1177)
                     /locus_tag="LP345_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL1760077.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            1381..2031
                     /locus_tag="LP345_001288"
     CDS             1381..2031
                     /locus_tag="LP345_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL1760078.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            2047..3774
                     /locus_tag="LP345_001289"
     CDS             2047..3774
                     /locus_tag="LP345_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760079.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            3771..5663
                     /locus_tag="LP345_001290"
     CDS             3771..5663
                     /locus_tag="LP345_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760080.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            6367..7236
                     /locus_tag="LP345_001291"
     CDS             6367..7236
                     /locus_tag="LP345_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBL1760081.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            7445..8470
                     /locus_tag="LP345_001292"
     CDS             7445..8470
                     /locus_tag="LP345_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL1760082.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            8509..9459
                     /gene="manA"
                     /locus_tag="LP345_001293"
     CDS             8509..9459
                     /gene="manA"
                     /locus_tag="LP345_001293"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBL1760083.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            9553..11256
                     /locus_tag="LP345_001294"
     CDS             9553..11256
                     /locus_tag="LP345_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1760084.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            11258..13291
                     /locus_tag="LP345_001295"
     CDS             11258..13291
                     /locus_tag="LP345_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1760085.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSYIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            13302..13742
                     /locus_tag="LP345_001296"
     CDS             13302..13742
                     /locus_tag="LP345_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1760086.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(13942..14904)
                     /locus_tag="LP345_001297"
     CDS             complement(13942..14904)
                     /locus_tag="LP345_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760087.1"
                     /translation="MIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEAT
                     YHYEKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYE
                     NIFSGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAA
                     MLSLVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLF
                     LSTISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVI
                     IGGDIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(15071..15748)
                     /locus_tag="LP345_001298"
     CDS             complement(15071..15748)
                     /locus_tag="LP345_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760088.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            16012..17778
                     /locus_tag="LP345_001299"
     CDS             16012..17778
                     /locus_tag="LP345_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBL1760089.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            17793..18230
                     /locus_tag="LP345_001300"
     CDS             17793..18230
                     /locus_tag="LP345_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1760090.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            18243..19394
                     /locus_tag="LP345_001301"
     CDS             18243..19394
                     /locus_tag="LP345_001301"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBL1760091.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19456..20154)
                     /locus_tag="LP345_001302"
     CDS             complement(19456..20154)
                     /locus_tag="LP345_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBL1760092.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(20147..21499)
                     /locus_tag="LP345_001303"
     CDS             complement(20147..21499)
                     /locus_tag="LP345_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBL1760093.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(21722..23122)
                     /locus_tag="LP345_001304"
     CDS             complement(21722..23122)
                     /locus_tag="LP345_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBL1760094.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            23283..24020
                     /locus_tag="LP345_001305"
     CDS             23283..24020
                     /locus_tag="LP345_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBL1760095.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            24145..24624
                     /locus_tag="LP345_001306"
     CDS             24145..24624
                     /locus_tag="LP345_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBL1760096.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            24621..25388
                     /locus_tag="LP345_001307"
     CDS             24621..25388
                     /locus_tag="LP345_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760097.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            25618..26187
                     /gene="lepB"
                     /locus_tag="LP345_001308"
     CDS             25618..26187
                     /gene="lepB"
                     /locus_tag="LP345_001308"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL1760098.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(26291..26893)
                     /locus_tag="LP345_001309"
     CDS             complement(26291..26893)
                     /locus_tag="LP345_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1760099.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            26999..27468
                     /locus_tag="LP345_001310"
                     /pseudo
     CDS             26999..27468
                     /locus_tag="LP345_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            27574..28158
                     /locus_tag="LP345_001311"
     CDS             27574..28158
                     /locus_tag="LP345_001311"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBL1760100.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            28161..29234
                     /gene="prfA"
                     /locus_tag="LP345_001312"
     CDS             28161..29234
                     /gene="prfA"
                     /locus_tag="LP345_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBL1760101.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            29227..30066
                     /gene="prmC"
                     /locus_tag="LP345_001313"
     CDS             29227..30066
                     /gene="prmC"
                     /locus_tag="LP345_001313"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBL1760102.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            30059..30238
                     /locus_tag="LP345_001314"
     CDS             30059..30238
                     /locus_tag="LP345_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760103.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            30260..31285
                     /locus_tag="LP345_001315"
     CDS             30260..31285
                     /locus_tag="LP345_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBL1760104.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            31460..32704
                     /locus_tag="LP345_001316"
     CDS             31460..32704
                     /locus_tag="LP345_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBL1760105.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            32857..33804
                     /locus_tag="LP345_001317"
     CDS             32857..33804
                     /locus_tag="LP345_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1760106.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            33938..34567
                     /gene="upp"
                     /locus_tag="LP345_001318"
     CDS             33938..34567
                     /gene="upp"
                     /locus_tag="LP345_001318"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBL1760107.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(34706..34948)
                     /locus_tag="LP345_001319"
     CDS             complement(34706..34948)
                     /locus_tag="LP345_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760108.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            35069..35141
                     /locus_tag="LP345_001320"
     tRNA            35069..35141
                     /locus_tag="LP345_001320"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35102..35104,aa:Thr,seq:cgt)
     gene            complement(35260..35898)
                     /locus_tag="LP345_001321"
     CDS             complement(35260..35898)
                     /locus_tag="LP345_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1760109.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(36021..36653)
                     /locus_tag="LP345_001322"
     CDS             complement(36021..36653)
                     /locus_tag="LP345_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL1760110.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            37004..37303
                     /locus_tag="LP345_001323"
     CDS             37004..37303
                     /locus_tag="LP345_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL1760111.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        12766 a         6614 c         7602 g        10772 t
ORIGIN      
        1 atccaaggca caaatgctgc tttgaagatt ttttcctctg tctcttttgt atgcatttat
       61 ctcaattttt aaaatgattt acctaaagca gcagctttat ctaatgcatt ttgcatcaac
      121 tcatctgcac ggtcagggtc ataatcgatt ccttcgatga atagctgatc tacttgatcg
      181 atgcctacaa agtttaaaat accttttaca tattgagagg caaagtcttg tccgttgtat
      241 acaccgccat tagattggat gtgcagtgct tttttacctg tcactaatcc ttctggcccg
      301 ttttctgtat agcggaacgt ttttccagct acattgacgg tatcgaacca agcttttaat
      361 tttgttggga tatttagatt ccataaggcg tttgcgataa cgattttatc agcagcaagg
      421 aactgatcag tcaattcatt gaaacgagca attttttgtt gttgactttc tgataaggaa
      481 gtgaattctg caccagcacg taatgcttcc caacctgata ataattcttc atcgatttcc
      541 ggaatatcat cgcgataaag ttccaaaaca gtcacttcat catctggatg attttcttta
      601 taacttgtta aaaaagacgt caatgcctta actgtgcgcg attcttctgc agttagggga
      661 tgacctttga ctactaaaac agatgccata tgcttacctt ctccttttat tgctatgatt
      721 gttataacta tgactaacaa aatcagttta ctcgaaaaag aaaaggctat caagtcatat
      781 tgataaggtt gaagaataaa taactaaaaa aagacagggt ataaaagagg ctgtgacacg
      841 attttttgtc acagcctctt ttgaatctaa caagcaatat tcaagcaaca ctcgactgaa
      901 gagcttccat cccaccaatg atataaacag cacgaaaacc attagcagta agttgatcgg
      961 ctaatgcttc tgatcgcctg cctgtatagc ttagaatata ataaagtttc tttggatcta
     1021 gattttttaa ttgtcttggc aagatagcag cggggataga aagcgagtgg cttaagtggt
     1081 tttttgtgta atctaaggta tttcttgtat ctaaaacgat gctgtcagca tcgagaggca
     1141 atttattgaa gtcttggaca ctaattgatt gggccattta tctcatcctt tgtttagtat
     1201 gtggctattt taatgggcaa ctctcattaa ttcaaatgga aggattcctc ttatcacttt
     1261 tttaatgtat cggatgataa tgaaaaaaac tatgcaaatg tcttgcaaaa caggtaggag
     1321 gtgttataat gacatagcgt catatgacaa tgtgtcatct tgaaagaaag gagaatccat
     1381 atgccgacac agacattttt ccatttgcct aaagaaaaac aaaaaagact aatcgaggct
     1441 gcgagaatcg agttttctag agtaccctta aaagaagctt cgattgctaa tatcgtcaaa
     1501 ttagcggata tccctagagg cagtttctat cagtattttg aagataaaga ggatctttat
     1561 ttttattact ttgagacaat gagacgtgac agctctaaag atatgttaca actaatgaaa
     1621 gaatccgatg gtgatctatt caaaggattc gaatcctatt tttctaaaat gatttatgag
     1681 attttggaag gcgagaatgc ttctttttat cgtaacttgt ttatgaacat ggattaccgt
     1741 gcctcaagaa aagtcgctcc tcatacgagt cgccaaaaaa cgcctcacga tccacataaa
     1801 gaacacaaac aagatgcaaa agagttgctt gaattgatcg atcggacgaa gctgaaagta
     1861 aaaaatgatc atgaattgga attactgatc caattagtga tgaatactgt atttacaaca
     1921 attgcgcatt cgtatcgctt attttcaaca tctgaagatt actcagtaga gcaagcaatc
     1981 agtgaattca atttgaaact ttcttggctg aaaaacggag tatataaata gaaagaaggg
     2041 aactagatgc taaaaatcgt aaaacggatc tccttgactt cagcaattgc agctgcagtt
     2101 ttcatggtga tccaagtact ggcagattta tatttgccga cacttacctc caatattatt
     2161 gataaagggg tagcgcaagg agatgtcgat tatatttggc atacaggttt tgtgatgatc
     2221 ggcttttctt tgatcagtat cttagctgct atcgcaaata cattttttgc tactcgtgaa
     2281 tcacagaaac tgggtaagca attgcgtacg gatgtctata aaaaatcaga gagtctgaca
     2341 aaagatgcgt ttgataaata tggaacggcc tctttgatca caagaacgac caatgatgtg
     2401 actcaaatcc aaatggttac acaaatgttt ttacgtatga tgatcaatgc accaatcacg
     2461 ttgattggcg cgagcatact tgcttatcaa aaagatcatc agttgacaaa aatcttctta
     2521 gttgtcatcc cagtaatgat tattttgatc ggcggaatca tgtactttgc tgttccatta
     2581 ttcaaaagta tgcaaaagaa aactgaccgt ttaaacctgg tatttcgaga aggattgaca
     2641 ggggtcagag tgattcgagc attcgataag acacgctttg aagaaaatcg ttttgattta
     2701 gcgaataaag attatacaaa tacggcaatc aaagttaata cgatcgtcgc attgatgatg
     2761 ccaatgatga cattgatcat gagcggtaca aacgtagcaa tcacttggtt tggtggacac
     2821 tacatagcag atatgacttt ggaagtcggt aatctgattg catttatgac ttatgcgatg
     2881 cagatcttga tcagctttat gatgctttcc gctattttta tcatggtgcc tcgtgcacaa
     2941 gcttcagctg accgtattaa tgaagtgttg gatgaaaaaa tcggtatcca tgaccctgaa
     3001 aatcctaaaa cagtttcttt tgctggaaaa aacgcaacat tggccttcaa tcatgtcaat
     3061 tatcgatatc atggagcaga aaaacttgca ttggaagata ttgatttcca agccaagtcg
     3121 ggcgagatcg tcgcaatcat aggggggact ggttcaggta aaacgacctt agtcaatttg
     3181 atccctcgat tatatgacat cgaatctggt tcgatccaaa taaatggaac ggacattagt
     3241 gacatgactc aatataattt gcgagaatta atgggctttg ttcctcaaaa agcagttctg
     3301 ttctctggaa cgatccgaga caatatgcag tatggtaagc cggatgcaac agatgaaatg
     3361 atttggaaag cattagaaat cgcacaagct aaagattttg tttcagagat ggaagatggc
     3421 ttagatagcc atgtggaaca aggaggagga aacttctctg gtggacaaag acagcgtctg
     3481 gcaattgcac gggcattagt caaaacagca gatatctatg tgtttgatga ttccttctca
     3541 gcgttggatt tcaaaacgga tgccaatctt cgccaagcat tgaaaacgaa tatgaaagaa
     3601 agtatcaccg ttttagttgc tcaacgagta agtacagtaa tggatgcaga tatgatcctt
     3661 gtgctagatg aaggaaaact ggttggcaaa ggaacacatg aagaactatt agcaacaaac
     3721 gaaacttatc aagaaatcgt tcattcacaa ctaagagagg aggacttagc atgagtaaaa
     3781 caaacacacg tccctctcat ggaccagcag gcggtccagg acatggtgga cctggcagaa
     3841 atctcggtgt aaaaggtgaa aagcctaaaa atttctgggg aacggtacgc cgattgtttg
     3901 gctatatgtc taaacgtatg gttgcgatca tcgctgtatt tgtactagca atagcagccg
     3961 tgatcttcca aatccaaaca ccaaaggtct tggggaaagc aaccacagaa atattcaaag
     4021 gtgtaatggc tggcgctcaa cagatgcaac aaggccaaca agtaacaaaa tttccgatag
     4081 actttgataa aatcgcgcag atcattgcga cagtaatcgt gatgtatttg atttctgctg
     4141 tattcaactt tttacagcaa tttattatga cacgtgtttc ccaacgaaca gtttatgaat
     4201 tacgtcatga tttggaagcc aaaatgaatc gtgtaccgat ttcctattat gatacacata
     4261 caaatgggga tatcatgtct cgagcaatca atgatatgga taacatcgca agcacgctgc
     4321 agcaaaattt gactcaattt gtaactagtg cagtcacatt gattggggtc atcgtgatga
     4381 tgctttcaat cagctggcaa ttgacgttag tcgcgttatt gatgatccct ttaagcttga
     4441 tcatcgtgat gatcgtagcg ccgaaatcac aagtgttttt cgcagatcag caaaaaagtt
     4501 taggtttatt gaataaccaa gtagaagaaa catatggtgg tcataccatt gttaaaacat
     4561 tcaatcatac tgaaaaagac caggaagtat ttgaaaaaga aaatcagaat ctgtatgccg
     4621 ctggttggaa agctcaattt atttcggcaa tcatcatgcc gttgatgaat ttcgttaaaa
     4681 atctaggcta tgtgttcgtc gctgtactag gcggagtaaa agttgcaaat gggaacatga
     4741 cattagggga tgttcaagcg ttcttgcaat atacaacaca gttctctcaa ccaatcactc
     4801 aacttgcaag tttgatgaac actatccaat caacagttgc ttcagccgaa cgggtatttg
     4861 aagtgttgga tgaagaagag atgtccaatg aaaaatctgg ccttccagaa gaaaaagata
     4921 caccatacaa agttcgtttt gaaaatgttc aattcggcta cacaccagat aacttgctaa
     4981 tgactgattt taacttggat gtcaaacctg gtgagatggt cgctattgta ggtccgactg
     5041 gtgcagggaa gacgacactg atcaaccttc ttgaacggtt ctacgatgtt tctggaggta
     5101 gtattcgtta cgatggtgta gatacccgtg atctttcacg tgatgaattg cgcgcacagt
     5161 tttcaatggt actgcaagat acttggctgt ttacaggaag tatctatgac aatatcaaat
     5221 atgggaacga cgatgcaaca gacgaacaaa tcattgaggc tgctaaagct gctcacgtag
     5281 acgattttgt tcgtaaattg ccagaaggat ataacactgt attaaacgag gatgcaagca
     5341 atatttcgca agggcagcgt cagctaatca caattgcgcg ggcattctta gcaaatccag
     5401 atgtcctgat ccttgatgaa gcaacatcta gtgtagatac acgaacagaa atactgattc
     5461 aaaaagcgat gaaccgccta ttggaaaacc ggacaagttt cgttgttgct caccgcttgt
     5521 ctacaatacg cgatgcagac aacattattg tgatgaatca tggttcgatc gtagaaacag
     5581 gaaaccacga tacattgatg gaaaaagacg gattctatgc agatctttat aacagtcagt
     5641 tttctgaaga agaagcttca tagaatagta caaatttatt atttttttta ggggctgtga
     5701 caaaagtcgt gtcacagtcc ctttttccga ataaacggtg ttcaatcagc tgtccttcgg
     5761 tattagctca aaaaacggca aaatatgaga agctattttt ccgttttgta tctctaatac
     5821 tcaggtcaaa ccgctgattt tacaacctct tccttaaacg gtgttctcct gccaactcct
     5881 cggtcacaag tcacaatagt caacaaacct gagaagctgt tttttgaaat tgctccttgt
     5941 gactcggagt taaacggcag gctcacaacc tcttggtaaa cggtgttcaa aagccagttt
     6001 ctcggtatta agccaaattt atgcaaaaat gtagaaagcc attttcacaa aatttttctt
     6061 actactcgaa actaagcgac tttttcacaa cctcttcctt aaacggtgtt caaaagcttg
     6121 catctgcggt aataagccca accaaacgaa aaataggagg agctattttt gtttggctgt
     6181 tcttattact tgatgcagaa cagctttttc acaacctctt tttataagag tttttactca
     6241 ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca ttttttttaa caaaatcaaa
     6301 gttattgctt gaaagaagaa gaatccatcg ttaaaataaa gcttgacgta gaggggagca
     6361 agaaatatga aagattttca attgggggct gccacctatt taaaaagtgt agccattcgg
     6421 gtgaaagacc gagataaaat gattgatttt tacaagaacg ttgttggctt tgatttgaaa
     6481 agagaagaaa acgaattagc cattttagga acagaagaag ctggaagtga aatgttgctg
     6541 ctggaagaaa gtcctagagc gaatgatcac atgggggtga tcaaaaagct gaaccgtttt
     6601 tcattgatta tccctagcac agaagaaatg gcagatatcc tttgtcgtat ccgtaaaatg
     6661 aattatccaa tcaaagaagc tttagaagat catggacgta tggggatttt gctcgtagac
     6721 ccagaagaga atgaattgga aatttaccat gaagagaata agaacgacca aagagaaatt
     6781 ccagaaacaa tggatcaaga agcattatta agaaaatctg aagaaaaatt cagtaaacta
     6841 tcaacaggtt cttattttga aaaaatccat ttaaatgtta ctaacttaac aaaagaacgc
     6901 caatttctta atcatgtact tggtttgaag gtacataatg aagaagaggg catccatgta
     6961 ttgaatgaag gagatttcca tgttggtttg acagaagcta gcggaggcgc aattgatttg
     7021 cctacagatg aagtgattgg acttgatttt ctgaaattca tgatcgatac tgaaagcatg
     7081 gaaggactga ttgctcactt gcagcaacta tcagttgatt tcttcttaga caaaaagcac
     7141 acagtactca caatctatga tgctatagga atcgaatggt ggttcgtcag tgagccaaaa
     7201 gaaaagaata aaactgacat tcgatgcgac gcttaacttt ttctttctta acgattgtcg
     7261 catgtctcgt cattttatga acggtcatac tatcgcttat tctagagata gaaagagaaa
     7321 atagtatacc gggggaaact gcgcggtttt tcgcgcagtt tttttgtgta aaaaaggttg
     7381 attcctcata gattaagctt taagcttgga ctgtaagaat ctgatagaaa agcaggagaa
     7441 aaagatgtat ccacacacga aacagcttat tttgaaaaag atggaagaag gattttatcc
     7501 aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa acatttacag ccggctttgc
     7561 ccaagtcgtt cctgaaaagc agctgatgac agaagatctg ttgtttgatg cagcctcact
     7621 gacgaaagtc gttgcaacca cttcattagt tttacgtcta ttagaagatg gaaagataga
     7681 actcgatcaa ccgcttcata aatatcttcc tgaatttgaa aatcagacaa tcactttgcg
     7741 tcatttactg acacatactt ctgatatcaa aacatggata ccaaacagag ataagctatc
     7801 tcaggaagaa ttgatcgccg cttatttgaa gctagaacca ggtgagcaac taggaaaaga
     7861 agtaaaatat acagatgccg gtacgattct tcttgggttg atgctagagg aaatttacca
     7921 agaaactgca gtggaaatct ttcaagaaca agtattggaa ccattaggaa tgatgaacag
     7981 cttatttctt ccttttcctt ccaaaaaaat cgttcccaca gaacaactgc cttcgggtga
     8041 ggttttgcgt ggacaaactc atgatccgaa agcaagagtt ttggctgaac atgcaggtaa
     8101 cgcgggtctc tttattgatt tgaaagacag cattactttt gtccaaatgt atttgaacaa
     8161 gggaaaaatc cgtaatggtc gttttttaga agaagagacg attgattctt tactgcaaga
     8221 tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg gacttaaaaa aggatgtaga
     8281 agacggtcat gcgattcttt ttcatactgg ttatacaggt acgtttttct tgattgatat
     8341 aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta catcctgtcg atcatcgtgc
     8401 ggagtatctc atatgtcgag atgaaattgt tgaaaacttt ttgaaagaga aagcggtatt
     8461 accgaaataa tgctataata gctatgaaaa atgagaggag tttgaattat gcaggaacct
     8521 atgtttttaa aaccagtttt tcaagaaaaa atttggggag gaagtcgttt acgttcagtc
     8581 tttggttttg atatccctaa cgataaaatc ggagaagatt gggcgatcag tgcgcatcct
     8641 catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga aaagattaga tgaactatgg
     8701 tcagaacaca aggaattgtt tggccatcct tcagaaccag tgtttccatt attgatcaag
     8761 atcttagacg cagaagatga tctatctgta caagtacatc cagatgatgc ctatgggatg
     8821 aaacatgaag gtgaattagg aaaaactgaa tgctggtata tcatcgatgc tgaacctggt
     8881 gcagaaatca tctatggtca tcatgcaaag acaagagaag aactagctga gatgatcaaa
     8941 gatgggcgct gggatgacct tttgaagaaa gtaccagtta aaaaaggtga tttcttttat
     9001 gtaccaagcg gaacgatcca tgctattggt aaaggaatca tgattttaga aacacagcaa
     9061 agttctgaca cgacttaccg cgtgtatgac tacgacagaa aagatgcgca aggacaaaca
     9121 agagagctgc atatccaaca atcgatcgat gtaacaactg tccctgcgaa aacaccagaa
     9181 ttacaaatca aagaagtccg aaaagggaat tcatcgatcg tcacttattt agaaactgag
     9241 tttttcaatg tatatgagtg ggatattaaa ggaatcacat ctttcaaaaa acaagcccct
     9301 tatacattga tgacggtaat cgaaggagca ggagaccttg tcgttgacgg aaaaacatat
     9361 ccattagaaa aaggaacaag ctgtattatt ccaaatggcg tttctgagtg ggcggtccaa
     9421 ggtgaactag caatcattgc gtctgaacca ggcaaatagt tcccagatag ctgaaagcag
     9481 cagacggttt ttcgtttgct gctttttcta cataaaatcc gtccatcaat aaatagaagt
     9541 ctggtgaaaa agatggaata caaatggaaa gcaaacaaca gcagtcgcgt gtctatgaaa
     9601 caactgagaa aagctggaca tcacctaaat gaaatgatca tgccaaatct aagtctgttt
     9661 atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt ctggcgattt gcacaccaca
     9721 ttagaagagg tatgccattg gatgatccag ctgcttttac ccatcttgat cagttattca
     9781 ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg gtgcaattgc ttctttaggg
     9841 ttgatcgctc gttccaatgc tccacaaatc gtaggagcga tgattatcgg gccgcttgcc
     9901 ggcatcgtat atgaacaatt tgtttctaga ttccatgtga aattcaaggc tggatatgaa
     9961 atgcttgtca gcaacctact agtaggactg actggtagcg ttatttgtat aattggaatc
    10021 gtttttattg aaccagtttt aaatagtgtt cacttgttgc tcgcctccgt tgtgtcttgg
    10081 ctagtcacaa tgaatctgtt accacttgtc agtctgatct tagaacctct aaaagtacta
    10141 tttttcaata atgcaatcaa tcatggtgta ttgacacctt taggaatcga attctcacaa
    10201 acagtcgggt actcttcctt atttttgatg gaggcaaatc ctggacctgg tttagggatc
    10261 ttactttcta tcctttgttt tgcagaaaaa caggaaaaag taaatgcgag tggagcattg
    10321 atgatccatg cgattggcgg gattcacgaa atctattttc catttgtctt gctgcgaccg
    10381 tatctatttt tagctgtaat ggctggtggg gcaagcggca cgttgatatt tcaatggtta
    10441 gatacgggat tagctgcacc tgtatcgcct gggtcactac tcgtgatttt tgccaatgcg
    10501 ccttatccac aactagctgg ggtaagtata gggatagcaa tcagtacatt tgtgaccttc
    10561 atttgtgcag cgatactatt gaaattacca aataaagaaa aagagaacaa aacggtcaaa
    10621 gaaaggggag aaatcttgga accatctatc attcattccg tcatttttgc ttgcgactca
    10681 ggtatgggat caagtgctat gggagccgcc ctgctgaaaa agaaattagc agcagaaaaa
    10741 atcgatcttt ctgtcggata cagctctatc tatgaattga ataaccaagt aaatcagctg
    10801 gttatcgtgc aacatgaact agcgggtctt gcaagagaaa aagtacctca aagtcaaatc
    10861 tatgtactgg atcacttttt ggaaacagat atcttgctgt cacgaataaa agaagcgatc
    10921 caatttccaa agcgggaaga aaaaaaagag atagcagata tcacagaaca aaaaacgtcg
    10981 cctgctaata ttgtattttt gtataaaaac aacagacgcg gctcacaaac tatgggcatg
    11041 acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt ttgttatctc aaaagaatca
    11101 atagaaaaaa tcaaaatcca agaagaaacg atttatatcg cacaaagaga actagctgta
    11161 actgaacagc tagaagaaaa gatccctcgg ctagttctag ttgaacattg ggtagctacg
    11221 aatgaatacg aaaaactcgt gaagggagaa atataagatg tatttatcgc ccagagaaaa
    11281 acaattatta gcagaatttc tcagtagccc gtcacctgta tctatccaaa aaatgatgaa
    11341 tttattgaag gtcagtaaac ggactattta ccgcgaatta gataatcttg aagtctcatt
    11401 gaaatcggta aatgcttctt tgaaaaaagc agctagaggc tcatttgtca ttgaggcatc
    11461 agaagaagta ttagagcaat taaaagaaaa tacagatggg aaaagtaatg acttatccac
    11521 tgctaaacga caacacgcga ttttagccga gttgttactg acgacagagc cgttgagtct
    11581 tgctcatttc atggaatcat atcgcatcag taataccact ttttatgcag atatcaaaca
    11641 gttggaagaa agtattcgcc aactgccttt ggaaatcatt cggaaccagg gatacgagat
    11701 cgaaggaccg gaaaaatacc gccggcttct gacagcgaat gtattagaat tagaaatcaa
    11761 tgaatatgaa ctttttcata gtatttcttt cgatgcatca ctgaattatt tttttcgatt
    11821 cgttgatccg caacatctat ctcttgcacg caaagtaatc ggggaagaat tgatccaaaa
    11881 aaagaccaat ctaagtgata gaaagcttga acatttggtt ttgatgctga cattgacgat
    11941 ggagcgtgtg acgaaaaatc atttactgac aaatgagaca tataatagtc tggcaaacaa
    12001 agaattacta cagacagcta aacgattgtt ttcacggatc gcttctgaga caaaacaact
    12061 ttatccagta aatgagatcg tcttttttgc aggattatta aatgacttca cgaactcatt
    12121 tgatcagaat ttctttgaag agacgttcga tacacagctt gcttatttag taaaacaact
    12181 gattcaagaa gtaagtgaag agacgaatgt ccatttttat gaagatgaaa ctttgtacaa
    12241 aatgctgttg actcatttat ctggtgtgtt ttcaagagcc gttttacaag aagagacact
    12301 gaccaatccg attttagaaa aaatcatggt tcaatacgag gaagttgcga atgcaatccg
    12361 taaagcagta gagcggattt ttcaagaaaa aaaattatcc gaagaagaga tcgcttatat
    12421 ggtccttcat tttgcgaatt cattggaacg aagtccgaaa gaaagcaata tcagtattgc
    12481 aggattttcg ccaagtggat tagcttctac tagcatgttg gaactacgat tgaaaaggta
    12541 ttttcccttc atccaacaaa ttcatttcta tcggattgct gatttaaaaa aaatcgattt
    12601 acaagaagaa tatgatgttg ttatttctac atctatttta ccaggatacg gtggaaaata
    12661 tattttagtc tccccgctac tgctagaaga tgaagtcaag cagctaaaag aagctttttc
    12721 gtatattgag aagaaaaaaa ggcaaaaaat tacgtataac agcaataacg agtggatgat
    12781 agaagatact tatgaggaaa caatgcattt catggatcaa atcaatcaat tactcggtcg
    12841 tttttttatc caagaactgg ataatcctga gacgatttcc gaaacgattc gcagcttatt
    12901 tccttatttt cctgaaggac tagtaacgga tgaagaggtg gttcatcgcc ggctgcttaa
    12961 gcgatatgaa caagcaccta tcggtattcc tcatacaaat atggggttat tccatacatc
    13021 cagctcattg atttctaaac cgatcttttg tattttcaat ttgaaacatc cgttgaccat
    13081 tgaagggatg gatagacagc cagtcgattt gtcccgtatg ttagttatgc tggcgccttc
    13141 gccaatccaa gaaaaagacg ggattctttt aggaaagatc agtggagcaa tcatcatgaa
    13201 tgacttgaac accgagatct tccgctcagg aaataaagaa atcgtttatc agttgttagc
    13261 gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa gatgatacag ctaccagcag
    13321 aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga agcgttgacc gagatcggcc
    13381 agtggatgac ccaacaaggg ggaatcaaac cggcatatat ccaatcaatg atcgaaagac
    13441 aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt gccacatggg actgacaaag
    13501 atgaagaagt agtagaagaa ggaatctatt tagtccaagt gcctgatggt gtggactttg
    13561 gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt agtggcttta aaaaaagaac
    13621 atcagttagc ggtgctccaa gatttagcct ttttctgttc agacatcgac caagtaatgg
    13681 cgctcagtga tgcggaaacc attgaagaag tccaaatgat ttttgaacat ggacatatat
    13741 aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt aataacttca accaagataa
    13801 aaataagagg agctattttt gttgggaggt tcttattact gcggatgcaa gcttttgaaa
    13861 actatttatt ctagaaaacc gtttatttga aataggggac ggtgacaagg tttttgtcac
    13921 cgcccctatt atttttgtgt tttaatagct cttttttata tagatagtgc ccatacctat
    13981 gaataataaa acgatactcc atataccaag tgtcaagata ccattcatga aagtaacctg
    14041 ttctgaagct agtggcgaga aaatatctcc tcctatgatc acattttgaa aatcaacata
    14101 agaagttggc aagtaatgac tgattgattc tatccatcca atcgaagaaa acaagcgata
    14161 ctctgctaag aaaagacaaa gaagtgtacc taaaagattg actagagaat gttcaaataa
    14221 agcagataga agaaaactga ttgtacttaa aaagagcacc cacaacaaca ggaacagaaa
    14281 gctctggaaa agatactcat acatcggcag gattcgtatc tcctgaccaa tgatcgttcc
    14341 tacaggataa cggaagtctc ccaaaccatt tttgattatt actagtatag agacgatcaa
    14401 aaatggcatc acgagactta gcatagctgc accataataa atggtaaaac ggatgctatg
    14461 tttctttacc atactatccg gtaatagatt gactagagag attacctgct ttcttttttc
    14521 ataagagatg atggaagaaa gaaacaaggc ggttatacat aaaatcaaaa aactagaaat
    14581 cattcctgaa aaaatatttt cgtagtaatt tgctaaagag agatgcgctg gcaagtcaaa
    14641 aatagaatat ctttggatct gatgttcttt catataacgg agcaactcga cacgtttttg
    14701 ttgttcaatg attggaattc cttgtctttg accagaaatc agtcgatcca gtatatcttt
    14761 ttcataatga taagttgctt cgaccatttg ctggacattc cctgtgtttt ttgcatgtaa
    14821 gattgcttcg atcagtttgt tgcttttctc taaactttcc acaaattctt tctcattctc
    14881 atcttctttc aacgtttcaa tcaaacgttg catctcttca tagttatgat tcagttcatc
    14941 gaattctgta taagcaagtt tatgatcaaa aaaagtggga atgcaaagag cacgaccaac
    15001 aatagaggaa ataaaaagtt tactttgttt tttagtaaga gattgcgttc aaatgtaagt
    15061 aaagacatag ttacacctca tataatttac gataaatagc taaaatctct tccatatttg
    15121 aggattctgt gacgatttct ccatttttta gaaaacatgc tttagaacaa atcgattgga
    15181 tattcgcgat agcgtgggaa gaaagaagaa tcgtcttccc ctctttctgc cattgtctga
    15241 tgaggctatt caagatatca atacttcctg ggtctaatcc gttcaacggt tcatcgaata
    15301 acatgacaga tgaatcactg atcaagtaag cagcaagcaa gacatgttgt ttcattccta
    15361 gagacatttt tccaatcggc aaagtaaggt actcagtcat cttcaatcgt tggaaaacag
    15421 tttggcattc tactttgctc tgccaatagt atttgatcaa agtcaaataa tcaacagccg
    15481 atagatagtc ggataactga ttcgttgatt ctagaaaaaa gaaagaccgg cgataatctg
    15541 tataagcagt aggagagatg ttgtgaaggg acaattgatc ataagttgtt ggcagcagtt
    15601 gggcaatgcc attcagcaaa gttgttttgc caaatccgtt cggggcaatc aaagcagcta
    15661 cttctcctga ttctactaaa agattcaatt gtcgaatcac acgtttttta ccacgtttca
    15721 tgttcatgtt tttgatcagt aatgtcatag ataggcctcc aatataaaat ttaataacat
    15781 aatagaatgg aaaacatcta aattaaatgc taacaaaagt tattgtttgc atattataaa
    15841 aaaattaaaa taacagtttt atttaaaatt gaagttttct gataccgaaa tctttttatt
    15901 ttgctgacat actcaaacct ttggcacaaa gtttcgtgcc aaagtacgac tatttctctt
    15961 tttagtaagc ggatacaatt agagtatcaa aaggagagag ggagagacaa aatggaacgg
    16021 acgattccca aaaacaacat ttcgctaaaa gcgagggtac aaaaattagg cagtacttta
    16081 tcaagcatgg tcatgccaaa tattggagca ctgattgcct ggggtgtatt aacggctcta
    16141 tttatcccag atggttattt accaaatgag gctttcgcta ccatggtaag cccaatgcta
    16201 acttatctga ttcctttatt gatcggttat actggcggaa aagtaattgc tggtgaccgc
    16261 ggatcagttg ttggggcaat tgcaacgatg ggtgtgattg tcggaacaga tattccaatg
    16321 atgctaggcg cgatgatcat gggacctctt ggtggatatg ccatcaagaa atttgatcag
    16381 ctattccaaa aacggatcaa atccggtttt gaaatgctag tcaataattt ttcagcaggt
    16441 cttatcggtt ttggattagc gttattaggt ttttctgcga ttggtccagt tgtcgatgca
    16501 ttgactcaag caatggcaaa aggtgtagag atcattttat ctgcccattt gattccattg
    16561 acaagtattt ttattgaacc agcaaaaatc ttatttttga ataatgcaat caatcatggg
    16621 attttgacac cattgggaac tgaacaagta gcagaggctg gaaaatctat tctattcttg
    16681 cttgaagcaa atcctggtcc aggacttggc gtattacttg cttttacttt gtttggcaaa
    16741 ggagcagcaa aatcttcagc accaggagcc atgatcattc actttttagg cgggatccat
    16801 gaaatctatt ttccttacgt tatgatgaaa ccgttattat tcttatcagt tataggcgga
    16861 ggaatgtcag gaagtttcat tttccaattg atggatgctg gactaagagc gccagcttct
    16921 ccagggtcga tcattgcgat tctagcgatg acaccgttca attcttacct tcctgttatt
    16981 ttgggcgtga ttgttgccgc agctgtttcg tttggtattt ctgcagtaat tttgaaagcg
    17041 gatgcgaaag atacaaatga agacttcgaa aaatctgttc aagagacaaa ggcagctaag
    17101 caagcttcca aaggtgccca aggtattcct caaggagcta cattctctgg cgtacaaaaa
    17161 atcatttttg cttgtgatgc aggaatggga tcaagtgcga tgggcgcttc gatcttgaga
    17221 aaaaaagtac aggaagcaga cttgcctcaa acggtgacca atcaagcaat cagccaactg
    17281 acagatgact cgaatacatt gatcgttact caggtcgaac tacaagaaag agcaaaacaa
    17341 aaagcaccga gcgcgcgttt tgtctcagta gaaaactttt tgaattcacc tcgatatgat
    17401 gaaatcattc aagaattaag cagcaagcag aaaacatcag tttctgaaat tgagaatgag
    17461 ccagcagaag agtttctttc agcaaacatc aaacaaatca aagagattct acttgtccac
    17521 gatgatcgtt ccggatcagc aacaatgggg atgaccgtgc tcaaagatat attagacaag
    17581 aaccatttaa ctatcccgtt aagaaaagtc aatatccaag atttaaaaga tgaacctgat
    17641 tcactgatcg tagccaaaga aagtttagcg gaaaaagtac agatggctgc acctcaatcc
    17701 attcatttat cagtcaacag catggtcaat ccgcaaaaat acgaatcgat tgcacaatat
    17761 ttgaaacaga cagcttaagg gaggaaaaca gcatgcaaag tttgccattc gacatgatcg
    17821 agctcaatcg atcttttaaa accaaagaag aagcgatccg ctattgcggt cagatgcttg
    17881 tagaagcagg gtgcgttgat gaggaatata tcgatgccat ggtagataga gacaaaatgt
    17941 tatctgttta tatggggaat tttatcgcga ttcctcatgg aacagatgaa gcaaaaaaat
    18001 atgtgaaaaa atccggcatc tgtgtcgttc aagtaccaga tggtgtagat tttggtaccg
    18061 aagaagaaga aaagattgcg actgttttgt tcggtattgc aggagtcgga gatgagcatt
    18121 tgcaacttgt acagcaaatc gcactttatt gcagtgatat ggacaatgtt gtccagctag
    18181 cagacgcgct cagcaaagaa gaagtaacgg aaaatctagc aattgcttaa ggagagagaa
    18241 aaatgagagc agtacatttt ggtgcaggaa atatcggtcg aggatttatt ggagaggttt
    18301 tggcagctaa tggatttgag attactttcg tagatgtgaa tcacacgatc attgatgctt
    18361 taaatgaaag aaaagaatac gaaatcgaat tagcagatga atcaaaagaa aaaatcactg
    18421 taaaaaatgt caaaggaatc aacaatcaaa caaatccaga aaaagtaatc caagaaatcg
    18481 ctgaagcaga tttagttact accgccattg gcccgaatat cttacctttt attgctgagt
    18541 tgattgcaaa aggtatccaa gaaagagaaa aggaaggaag cacaacatct ttagatatca
    18601 ttgcctgtga aaatatgatt ggcggttcag catttctaga aaaagaagtg tataaatatc
    18661 ttccggaaac atcatttact gacaaatata tcggctttcc aaatgcagca gtcgatcgaa
    18721 tcgtcccatt acaacaccat gaagatcctt tattcgtcca agtggaacct ttcaaagaat
    18781 gggtcattga cgatagccaa agaaaaaata aaaaaatcca attaaaaggg gttttatatg
    18841 tagatgatct agaaccatat atcgaacgca aactatttag tgtcaatact ggtcatgcga
    18901 ctgtcgctta tacaggtgcc ttgttaggtt accagaccat tgatgaagca atgcaagatg
    18961 cgttagttgt ggcacaatta aaatcagttt tgcaggaaac aggaagtttg ctgattgcca
    19021 aatgggggtt tgatgcagag cagcatcatg cgtatattga aaaaatcatt catcgcttcc
    19081 aaaacaaaaa tatctctgat gcgatcacac gtgtcgctcg gacaccatta cgtaagttag
    19141 gttatcaaga aagatttaca cgtccagtga gagaactaca agaacataac ttgacttgcc
    19201 cacatttgac ggcaacaatg gggattattt ttaattacta tgatcctgaa gatgaacaaa
    19261 gccgtcaatt gcatgaaatg aagatccatg aaaacttgga acaattgatt caagaagtca
    19321 caggaatcaa tgatccgaaa acaatcggga atatcaagca aaacgtgaac cgttatgcca
    19381 agcaagtcgc ttaaaatagg atacgaaaaa ggggaatgtg acgaaatttt tgtcacattc
    19441 ccctttttcg aataactagg ctgtttgtcc ttcaagatag ggcagatcca attctttacc
    19501 gtaacgttgt tctaaagcta ggcggatcaa acgagctgcc aggttctcat ttcttgcaag
    19561 gataggtcca tggaaataag aaccgaagac atttcggtaa atgacacctt cagattggtc
    19621 ttcaccatta tttccttgac cttgtaccac tttccccaaa ggtcgttcac cttcacctaa
    19681 gaaagtccga ccattgtggt tttcaaatcc ataataagtt tcattgaatt cttcgttatg
    19741 gataacgata tcaccgataa accggttatt ttcctgactt aacgtgtagt gatccagtgc
    19801 actgattcct tggatctttt ctccattagc tcccatgtag tagtgaccta gcaattggta
    19861 gccaccacaa atggctaaca tgacgccatc attttcgata tagttgatca aagaatcttt
    19921 ctttttctgg atgtcttttg aaatgattaa ttgctcaaag tcttgaccac cgccaaagaa
    19981 aaccaagtca tatttatcag catcaaaagg ttcatgtata ctaacgatct ccgtatggca
    20041 agaaaccccc attttttctg ctatatattt caacatcaaa aggtttccgt tatcaccata
    20101 tgtgttcatc aaatttccat aaaggtgggc gatattgagt tcataattag ccacggttca
    20161 ttcctccttt gataaatcct tgagcagcta gttctttacg aagctgcaat acagcagtgt
    20221 aagtagctaa aatatagaca tgctcagttg gcaattcttt gattttttcg attacttctg
    20281 gtaattcttt tgtttctgtc aatttatttt ctggaatccc ggcaactttt agacgtaaag
    20341 tcatatctgt atgacggtct cctccagaaa taacagctgg gatatccata tcggcaaagt
    20401 tttcaaaatt accatcccaa atccagctga catcgattcc gtctgcgtaa ttggcattta
    20461 ataaagccac taaagaaaat ggataaggag ctagaccaat catatcgatt acttgattga
    20521 tacctacagg atttttgaca agtactaatg tacatttttt cccattgata ttgatgactt
    20581 cttgtcggcc gaatactttc tcgtcatatc ctaaaccttg tttgatttta tcaggatcga
    20641 cattgaagta ctctgccact gcagtagctg ctaaagcatt gtagacatta tacataccgc
    20701 caacttcgat tccgtattca tgaccatcga tcacgaaatc tgctgacaca ttgtccatcc
    20761 gtaccatatc agttaatcga taatccaatt caggacgttt gaagtcacaa tttggacagt
    20821 aatatttccc taagtttgca taagtgatca ttttataatg caagatgtga tgacaatttg
    20881 gacataagac accgtctgta ttgtaatgag ccatttgttc acgatcttct tcatggtcaa
    20941 agccataata ttttctagga ttgactgttt cgatagaatt gaagattggt gaatcaccgt
    21001 tactgataat cgttgcattt ggtgactttg cggcaccgtc tacaatcatt ttataggtcg
    21061 tatagatttc tccataccga tccatttgat cacggaaaat atttgtaaat aagaacagtt
    21121 ctggtttcat atattctgtg actttgctca aacttgcttc atctatttct aggacagcaa
    21181 actttttctg tccttttttt ggttttgcct gcaagaaagt cgatacaatt ccctgtacca
    21241 tattcgcacc agtagggttg gttagaactt catcgaattg ctggcgcaaa atattgactg
    21301 ttaaagcggt agtcaatgtt ttaccgtttg ttccggtgac aacgacgact tggtagtctt
    21361 ttgccaaact atctagtata tgtggatcga ctttcagcgc tagtttacct ggtaaacttg
    21421 atccgccttt aaaaaaagtt tttaatgccc attgcgacgt ttttccaact gcaatcgcaa
    21481 aatgactgcg tattcccatt atgtaacctc caaaaacgat ttgctgacga ataaattcaa
    21541 ctaatcatac catatgttga aaaaaaggtt aaattgcttt tcttattctt aagaaaaggt
    21601 tacggctgaa agtgcatgaa atcggacaaa atcgcatgat ttaacaaaaa aacagcttga
    21661 aacaaaatga ttgtttcaag ctgctgtgat tttattattc cctcttacct atattcccat
    21721 tttaaccgat aataattttc tcgcttggat attcatagcc tagatctcgt gtttcttttg
    21781 gcacgaataa catcaatgta tatagcattc cgatccgccc aataaacatc agtgtagcaa
    21841 tcgtgatttt gcccacaaca gacaagtctc cggtaatccc taaagataaa ccagttgttc
    21901 caaacgcaga agttacttcg atgatgatcg agatcagcgt ttgttcttct gtagcagata
    21961 aaaaaacgat acaaaagaaa cacataccaa gagaaagcat aaagacaacg actgattttc
    22021 gcacatcatc ttgatcgatt ctccgtccaa aaatattgat gttatcttca cttttgagga
    22081 aggaatatag atacaaaccg atgattgcta cagtagttgt tcgaatcccg ccgcctacag
    22141 aactaggact gcatccgata aacatcagta aagaaaaaat gatcagtgtt gtgatttgaa
    22201 aatcacccaa atcgtgaatc tgcagaccag cattacgagt cgtaatcgaa taaaacatcg
    22261 aattgatcca tttgacactc atattggaat cttggaataa atggtccttt tccaatagat
    22321 aaatcaagac agttcccgaa acaaacaaga taacaaaagc taacacagct aatttggtaa
    22381 acaaggaaaa acgaaacgga agcttcgcat tggaacgttt gtataatagc cattcccggc
    22441 actccatcaa tacaggaaaa ccaattcctc cgacaaaaat caaaaacatg atcaggatca
    22501 agaaaaaata gtcatgtgca aagggcttga tggaatcccc agtgacgtca aacccagagt
    22561 tcgtgacagc cgatatcgcc tgataaaaac cgtaaaaaac ggcatcacgc caacgatcaa
    22621 aatagcctct gtaataaaaa taaatagaaa agaatgtccc aaaaagtaat tgaaaccaga
    22681 ttaaaatagc aaaagtgatc cgaatcagtc ggacgatacc agacaaacgc ggttgattca
    22741 tatccgtcat gatcagctgt cgctgtttca gtgtgatccg tcgtttagaa aaaatgacaa
    22801 aagcagtaga aatcatcatg atccccaaac caccaacttg aaataatatt tccagcagta
    22861 taataccgtt atcattgaac acagaattga tatcaaaagt cgatagtcca gtcacactca
    22921 ctgtactgat tgccatgaac agcatgtcca caaaagaaac atggctatct ggttcgcgaa
    22981 aaatcggcat ataaaataga acgagtgata agaccgtcat caatatataa taaaaaacga
    23041 tgatttggat cgatgagaaa tgattggcag caaacttctg tcctcgccgc tgcagccttc
    23101 gaaagaataa atcaacatgc acagtactat cctcctgaca atagtcgttt ctaccagtat
    23161 acaaggggaa ttaggaatac tcaaagaaat tatcaaacag ataacaatac agctttcgat
    23221 taaaatagaa atggcttata ataaggaaaa tcctagaaaa aagaaggagg aggaataaca
    23281 aattgattaa tgctcaacaa atcgtagaaa aaatgaaaaa tcaaaaaata aattatgata
    23341 cagttctgaa aaaaatgatc atgcaatggg agaaagaaga agtaaagcct aagatattaa
    23401 tacatacatg ctgtgctcct tgcagtacgc acacattgga attcatgtct caatatgcag
    23461 agatcacgtt atttttttca aattcgaata ttcatcctaa aagtgagtat ttgcgaagat
    23521 tacatgaaca aaaacgattt gtagaccaat ttaatgagaa aactgaccat catgttgcgc
    23581 taatcgttga tgaataccgt ccaaatgaat tcaccaaaat ggttttaaca aaccatcttg
    23641 aaaacgaaaa agaaggtggt gctcgctgca gtgcatgctt caatatgcga ttagatcttg
    23701 ttgcgcaaaa agcgcaagaa ctaggatacg attactttgg aagtgccctg accatctcgc
    23761 caaagaaaaa tgcagctttg atcaatcaga tcggaatgga tatccaaaag atttacggga
    23821 cacaatactt gccaagtgat ttcaagaaaa acaaaggcta tgaacgctct ttgcaaatgt
    23881 gcaaagagta tgatatttat cgccaatgtt attgtggttg cgtgttcgct gccaagcagc
    23941 aaggatgcga tctgaaagaa atcaatcggg aagcaaaagc ttacttaaaa acatcaaccg
    24001 tagtttttga ggaaaattaa agaaatcttt cggaaaaacg taagaaaaaa ataaagaatt
    24061 tatggtagaa ataaggtaga ctgtataatt tgtccgtagt aaagtaagga aacaagaata
    24121 aatttcaatg aaggaagaga taagatgcga aaagtagcac ctattttgaa gccaatcgct
    24181 gtattaacaa tctcgacgat tgtcgcgact actacaggta ttgtgaatag ttccagctac
    24241 cgtgcaccaa gttcaagttc tagtactgta gaagaaacaa caccaactac ttcagtctcg
    24301 acatctgaac caacaacaac ggaaagtttg aatgaaacca ctacgacaag tacatgggac
    24361 gatacaacaa ctagttcgtc gtatgatgag acatatacaa ctgacagctc aagcgaaaca
    24421 agtaatacgg taccagatgg cactccatcg gattcaacca atccaagtac aagtccggat
    24481 acaagtgcta gctccgaaac gataccaagc agtacgactg tagatgataa cacgcaaaat
    24541 gatgatgcag cacgtacagc acagcaaaac caagattcag gaaataccca aacgtataac
    24601 cagcaagcag gtgattctca atgacatttt tactagacct tatcaacggg gtgcataaat
    24661 tccttggcta tttagacatc agtcctaaat atcttaaccg tggatatacg attttaagtg
    24721 tgattcccac gctttattta ttgagaattg tttatggact ttggcaaaac caaaactatc
    24781 ttcaattttt cttatatgga cttgcatttc tagtgcttgt ttattttact gttttaaatg
    24841 tattttatta ctttttagat aaaaacacga aagccgatgt cactcagctt tttgtgaagt
    24901 atttacctga tgaagcgttc aacatccaga cagaagaatc gatagataat ggaaattcga
    24961 tcgataaagt gaatacacaa gaggtcatgg tttcttatga cgaagattat caattgaaat
    25021 tagccgagaa tatgcggtat ttgattggaa atggtgagat caaaacaaat gaactcggtc
    25081 gcatggatgg atttctggtc gatagaaata cattgtatcc ttattactat gtcaagaaaa
    25141 caggagagaa agagtatgtt ctaaatattg gacgaagcta ctcggacatg gaaaaagtag
    25201 ggaccattcg acttgactca acagaagaca cattggaacc tgtcggattg ttcatcgtcg
    25261 gcggtgattt tgtcaaagac gggttacgct atcatgagcc ttatcgtctg aaattgattg
    25321 caaaaaaggc acagtcgcag gaagaaccag tggtttatag tcgtagccaa agaagaagac
    25381 attcataatg tgatgaaacg ccgtgtatca gtggttgcga taaaaacgtt tattcggaat
    25441 aagggggatg tgacacgtct tttgtcacgt tcctttttta tataacgaga aagataagac
    25501 gaacacatca cttattcttt cctttcattt ataaacattg tagaataaag aaagtacaac
    25561 gaagtattgt gaaaaaacgt aataaataac gaggaaaata caagtaggag gtaagctgtg
    25621 aaagaatttt tgaaaaattg ggggattttg atccttgtat tagcggctat tttattagct
    25681 agagtgtacg tgtttacacc agttactgta aacgggcatt cgatggaccc tacattaagt
    25741 gatggacaac gattgatttc atctaagatc tcaaactatg aacgaatgga tattattact
    25801 acaaaggaac cgggggatga agaacggatg attgttaaac ggatcatcgg tatgcctgga
    25861 gatacagtca agatggaaaa tgaccagttg accattaatg gcaaaaagta tgatgaacct
    25921 tatctggatg agttcaaaaa agaattttca gaagataagt tacaaggaga atatgcttat
    25981 agctcaggat tccaagcaca agcagaaagt tcatccacct ttacgagtga ctttgaatat
    26041 actgtgccaa aaggaaagta tcttgttcta ggcgataacc gcttgatttc aaaagacagc
    26101 cgaatgtttg ggttagtcga caaagatatg atccaaggaa aagttgtttt ccgttattgg
    26161 cctctttcag aaattaaaat catgtgatga aaaaataaaa agaagctgtg acatgttttt
    26221 tgtcacagct tctttttccg aaaattcctt cttatttctt ggagttgctc actttttttg
    26281 caatctcatt ttaagctttt tggctgatgg ataagaaaag cgaagcgttt ttgttcataa
    26341 atagcttttc cccacgatgg aaggtatgac tagtagcaga gacaaagccc gttttttcca
    26401 atcgattatt caattcttct tggctaaagc cattatggac tttcggatga ctaatttgtt
    26461 cattcttgtc aaagtctacg atgatcaatt gaccgccagg agctaaaatt tcataaagtt
    26521 ttgtaagaat attctccgta tcaggaatgt gtaaaagtac aagtgataga aggatgagat
    26581 tagcttggac agcaggaaat tcgacagaag catcagcgtg gatcgttcgg acatttttca
    26641 gatctgctgc ttggatcttt tcttctgcca ttttcagcat agtttctgaa gcatcggcaa
    26701 tgatcagttc tttgaatctt tccgcaagcg gtaaactaac aagcccagtt ccgcctccgt
    26761 aatccagcag gactttttgg tggctgtcgc gcggtagata agtagttagt tcttcgcgaa
    26821 taatcttggc taatgcttga cggtcagggg aatcataatg gttagcgatg gaatcaaaaa
    26881 tattttttgt catcaaatag ctccttacgt aaaactttga aattttaact tattatagca
    26941 cgtgaaaaga aagaaagcat gctatactca attcaaaaag ggagaatcta gaaagaatat
    27001 gccgatatcg tttgtaaaag atagagagga aaaaggaaag tgtgtccgag aaatattact
    27061 agacttgcct gagtggtttg ggcttcctga atcaacggaa aaatatatcg aggaatcaag
    27121 taaactacct ttatggtgtg aaaaaagaaa agaagaatat ttaggcttta tcactctttc
    27181 acagacaagt gaagatactg ccgaaatcta ttctattgta tgggaataaa aaaagactat
    27241 catcaccaag gattaggaac aaaacttttt aaagaagcag aaggttacgc agcaaaacat
    27301 tacaaatatt tgcaagtgaa gactgtagac gaggggcact actctatata tgatcaaact
    27361 atttgtttct acgaatcatt aggattttca aggttggaag tttttccaaa tttatgggat
    27421 gaatggaacc catgtttagt tcttgtcaaa aaattggaac aaaagtgagc aatagattta
    27481 atactaatct gtgcttgatg aaaattctca ctgtaaaaaa tgctgaaaat caagtataat
    27541 accataggaa caaactggaa ggtgaaaaag agcatggcac aactattttt taagtatggc
    27601 gcaatgaata gcggcaagac gatcgagatc ctaaaagtcg cacataatta tgaagaacaa
    27661 aataagccag ttgtcttaat gacaagcggt attgatacaa gagatggttt aggcgttgtt
    27721 tcaagccgaa tcggactgaa acgtaatgcg atgccgatat ttgaagaaac agacgtattt
    27781 gacgtaattc agaaaatgga aagcaaaccc tattgtgtgc tgatcgatga agcgcaattc
    27841 ttaaaaaaga aacatgtcat tgcttttacg agaattgtgg acgaattgga tattccggtt
    27901 atggcatttg gtttgaaaaa tgattttcga aacgagttat ttgaaggatc aaaatattta
    27961 ttgctttatg cagacaaaat cgaagaaatg aaaacaatct gttggttctg ccacaaaaaa
    28021 gcaatcatga atttacatta tattgatgga aaccctgttt atgaaggcga tcaagtgcaa
    28081 attggcggaa atgaagctta ttaccccgtt tgtcgaaaac attactttca cccatcaatg
    28141 attacagaag gagaataagc atgtacgatc aattacaagc aattgaagac cgttatgaag
    28201 agcttggaga acttttaagt gacccagaag tgatttctga tacaaagcgt tttatgcagc
    28261 tttcaaaaga agaagcaaac acgcgcgaaa cagtcgaagt ttatcgtcgt tataaagaag
    28321 tagtacaagg aatcaccgat acagaagaac tgcttggtga aaaactggat gatgaaatgg
    28381 ctgaactagc aaaagaagaa ttatctgaat taaaaaaaga aaaagaagtc ttagaagaaa
    28441 aaatcaagat cttgctttta ccaaaagatc caaatgacga taaaaatatc atcatggaaa
    28501 tccgtggagc agcaggcgga gacgaagcag cattattcgc tggcgatctt ttcaatatgt
    28561 accaaaagta tgctgaagca caaggctgga aaacagaagt gatggaagct aacgttaccg
    28621 gaatcggtgg atataaagaa gtgatcatga tgatcaccgg agacaacgta tattcgaaat
    28681 taaaatatga aagtggtgcg caccgcgtcc agcgtgttcc ttcaactgaa tcgcaagggc
    28741 gtatccatac ttccaccgca acagttgtcg tgatgccaga agctgaagaa gtagagatcg
    28801 atattgaaga caaagatatc cgtacagata tctatcatgc ttcaggtgct ggcggacagc
    28861 acgtcaataa aacagcatct gctgtacgtt tgactcactt accaacaggg atcgttgttg
    28921 ctatgcaaga tgaacgttct caaatcaaga accgtgaaaa agcaatgaaa atcttgcgtg
    28981 ctcgtgtgta cgataagatc cagcaagaag cacaaagcga gtatgatgcc aatcgaaaat
    29041 cagcagtcgg aactggggat cgttcagaac ggatccggac gtataatttc ccgcaaaatc
    29101 gtgtgactga tcatcgtatc ggattaacta tccaaaaatt agatcagatt ttagcaggga
    29161 aattagatga gatcgttgat gcattgatca tgtatgatca aacatcaaaa ctggaagcta
    29221 tgcaaaatgg gtaaaatgac ctatcgagaa gtcctgtcac gggcttcttc ttttttagag
    29281 gatcatggga aagaagcata tagtatccaa tttttatttt tggaacgaaa acaatggaaa
    29341 aaacttgatt ggctccttca tatgaacgaa gagatttcag aagaagaaca gcggttgatc
    29401 gaaaccgatc tgcgacttct gcttgcagat catccacctc agtatttgct aggatatgca
    29461 gatttttatg atcatcggtt aaaggtaact gaagcaacac tgatccctcg accagaaaca
    29521 gaggagttag tcgaatggtg tttagacgag acgcctggtg taccgttaga agtgatagat
    29581 attgggacag ggactggagc aattgctatt agtttgaaag cagcaagaaa aaattggcat
    29641 atatctgctg tggatctttc agaagaagca ttagaagtag cgaaagaaaa tgctcagaaa
    29701 gaaggaacga aaatcagttt ttatcatgga gatacattag gaccagtaat ggatcagcaa
    29761 tttgatgtga ttatttctaa tccgccgtac atcagtcgga atgaatggga actgatggat
    29821 gaaagtgtcc ggtcattcga acctaaaatg gccctttttg ctgagaacga tggattagct
    29881 atttatgaaa aaatagcagt tgaagcacca agcgtactaa aatcaaatgg aaagattttt
    29941 ttagaaatcg gatttcgcca aggtgaagca gtaaaaaaaa tatttcagca agcatttcca
    30001 gataaaaaag tggcgataaa aaaggatctt tttggcaatg aacgaatgat ccaagtttat
    30061 ggttgaagtt gtggatgaaa aattttttat ttgttttttt attataaaaa aacacttatt
    30121 tgacaaggat gtaaacgact ttttggttta tcaacaagtt tatccactat tgacaaatag
    30181 attatccaca aacagtggaa aacttgagga taaactcaga caaaataaga atgtatgaaa
    30241 aaggggttgt ggataaactg tggaaacgaa acgatatgat gaaacagaat tgcaagaggc
    30301 agccgaagca ctgaaagaag gagaacttgt tgcttttcct accgaaacag tatacggatt
    30361 gggcgccaac gctcttttac caaacgctgt caagaaagtg ttttctgtaa aagggagacc
    30421 gcaagataat ccattaatcg tccatgtcgc ctcttttgaa caagtaaaag agtatgtgga
    30481 caactttcat ccggcagcag agaagattgt gaagaacttc tggcctggac cattaacttt
    30541 gatatttaag atcaaaaaag acactttgcc ctcagttgtg acgggaggat tatccacagc
    30601 tgcatttcgt ataccggata acaaaaaaac actagaagta atcgaacttt ccggtgttcc
    30661 gcttgtcggt ccaagtgcaa atacgtcggg aaaaccaagt ccaacgactg cagatcatgt
    30721 atatcatgat ctacaaggaa aaattaccgg gattattgat gatggagcta cgcgaattgg
    30781 tgtagaatcc actgttcttg atttaagtga tccaacagcc atgcctatga ttttacgacc
    30841 aggtgcagta acgaaagaac aaatcgaagc agtcatcgaa tctcctgttg ctattgatca
    30901 gcatcttgta aaagaaaatg aaacaccaaa agcccctggg atgaaataca aacactactc
    30961 acccgataca cgtgttctga tggtcagaga tggcgattgg tcaactgcag ttcaatgggc
    31021 aaaaaataag aagatccgtg caggtgtcat agcaagcccc gaaattgcgg atcaagtgcg
    31081 gacagatact gcagctgttt atatgtataa cgacaactca gtagaagcgg cggctaaagg
    31141 attgtttgca ggtctaagag gattagatga accaacactt ggattagatt tgatttttgt
    31201 acaagtgtat ccagaaactg gattggggaa tgcttacatg aatcgcttga aaaaagcagc
    31261 aggacaaaat tattttgaaa aatgatcaat tggttattgt cgcattcttt tagtatgata
    31321 caatgctatc aagtaaatct tctatcagtg aacgaaaaac taagcgtaac taatcgtaat
    31381 agaagagata cgaatatttg gcaatttgtt tttgatggga aaaataaaat tgtaggaaaa
    31441 taaaaaggag ctgttgtttg tggtagatta caaaacgttt gaccctgatc tttgggctgc
    31501 gatcgccaaa gaagaagaaa gacaagaaca taatttggag ctgattgcct ctgaaaactt
    31561 tgtctccgaa gcagtgatgg ctgcacaagg aagtatcttg acaaataaat acgcagaagg
    31621 ttatccaggg catcgctatt atggtgggtg tgaatttgtc gatatcgttg aaaatttagc
    31681 gattgaccgt gcaaaagaat tattcggagc gaaatttgcg aacgtccagc ctcactccgg
    31741 ctctcaagcc aacacggctg cttatctcgc tttggtagaa ccaggggaca cgatcttagg
    31801 aatggatctt tccgcaggcg gacatctaac acatggatca ccagtcaact tcagtggcaa
    31861 aacctatcac tttgttgctt acggtgttga tccgacaaca gaagttattg attataatgt
    31921 ggtacgtatt ttagctagaa aacatcaacc aaaattgatc gtagcaggtg ccagtgctta
    31981 cggacgaacg atcgactttg cgaaattcag agaaatcgca gatgaagtag gcgcaaaact
    32041 gatggtagat atggcacata tcgcaggatt agtagcagca ggacttcatc ctaatccagt
    32101 tccttatgca gatatcacaa cgactaccac tcataaaaca ttgcgtggcc ctcgaggcgg
    32161 catgattttg acaaacgatg aagcattagc aaaaaaaata aatagtgcgg tatttcctgg
    32221 tattcaaggc ggccctctag agcatgtgat tgcgggtaaa gcagtagcat tcaaagaagc
    32281 attagatcct gcatttaaag aatatagtga acaaatcatc gccaatgcaa aagcaatggt
    32341 caaagttttc aatcaagcaa ttggaaccag agtcatttca ggggcgacag ataatcatct
    32401 gatgttgatc gatgttcgcg agttaggtat aaatggaaaa gaagcagaga gcattttgga
    32461 cagtgtgaat atcactgtaa ataaaaactc gattcctttt gaaacactaa gtccattcaa
    32521 aacaagcggt attcgaatcg gcacgccagc aatcactact cgcgggttca aagaagaaga
    32581 tgctgtaaaa gtggctgaac tagttgtcaa agcattacaa gcaaaagatg ataacgctca
    32641 actagacgaa gtcaaaacag gtgtacgcga attaactgaa aaatttccgt tgcataaaaa
    32701 ataaaaattt aaattccatt agtaaacaga aaagttcaat gttgggcttt tctgtttatt
    32761 ttttgggaaa acggattctt tgacaatatc ggtgatgctc tctagtatat gaggtgtaat
    32821 tttagtcttc acactaaatc tcagggagga aaagtcatga ctgatcgtat ctcgttagaa
    32881 aaggaagcag tagcattcag tgatgcaaat gcgcctcatc cgcgtatcta tgaactagca
    32941 ccggaagaag gaagagtttt actagaagaa gtacaagaat cacctgtgaa caaatattcc
    33001 gtcgatattg aagacttgat ggtggatact ggcgaatggg gaaaactcaa tattcgtctc
    33061 gtacgaccag aagggaatat ggataaatta ccagttattt tttatattca tggagcaggc
    33121 tgggtttttg gcagtgctca aacccatgat aaattgatca gagaacttgc ggttcgtacg
    33181 aattccgtcg ttgtctttcc agaatatagt cgatcaccag aagcaaaata tccaacagca
    33241 attgaacaaa attatgctgt gttgcaacag ctgaataaat tagccaagtc aaaaaatctg
    33301 gatctcgaga atctaatcgt tgcaggagat tcagtaggtg gtaacatggc tacagtcatg
    33361 acgatcttaa caaaagaacg aaagggcctc ccaatatcca agcaattgct gtattatcca
    33421 gtcacaaacg ctgattttga tacagattcc tatcatgaat tcggagaaaa ctattttttg
    33481 acaagagaag gaatgatgtg gttttgggac caatatacga cgaatgaaga agagcgtgct
    33541 gaaatcacag cttcgccttt gagagcaaat ataaatgaac taaatgatct tccttcagca
    33601 atgattttaa cgggagaagc ggatgtatta agagatgaag gtgaggctta tgcgcgcaaa
    33661 cttcgtgatg caggggttcc tgttacacaa gtacgcttcc aaggaatcat ccatgatttt
    33721 gtcatggtaa atgctatgga tcagacaaag gcaacgcgtg cagcaatggc attatctact
    33781 tcttggatca agaaaaaaga ataagctttg cttgtccgca ggaaaacttc ttttcaaaaa
    33841 cggattttct taggaaaaat ggcgagtttg actagtcaat cacttgattt tgttttacaa
    33901 ttaaaaagaa acgacagaac aaaggagagc ttaaaaaatg ggcaaatttc aagtgatcga
    33961 tcatccattg attcaacaca aactaactat tattcgggac aaaaactgcg gaacaaaggt
    34021 ttttcgtgaa gtagtcgatg aaatcgctat gttgatggca tatgaagtat cacgggatat
    34081 gccattggaa gacatcgtga tcgaaacacc gatcactgaa acaacacaaa aaacgttgtc
    34141 tggtaaaaaa gtagcgatta ttccaatctt gcgcgcaggt attggaatgg ttgacggtat
    34201 cttggaattg attccagctg ctaaagtggg acatatcggt ctttatcgag atgaagaaac
    34261 attggaacca catgaatatt tcgtcaaact tccagaagac attgatgcac gtcagttgtt
    34321 tgtagtagat ccaatgttgg caacaggcgg atcagcaatc atggcaatcg atgcattgaa
    34381 agaacgtggc gcgtcgaaca ttaaatttgt ttgtttggta gcagcacctg agggagtaaa
    34441 agctttgcaa gaagcgcatc ctgatattga catctataca gcttctctag atgaaaaatt
    34501 gaatgaacat ggttatatcg ttcctggact aggggatgcg ggtgaccgtt tgtttggtac
    34561 aaaataagta aatacgaaaa agggtgtgac acaacttttg tcacatcctt ttttggtcat
    34621 ttttaacgtt tgatgcagaa cagctttttc acagctttcg tttgcatata aaaaaaccat
    34681 cccaaaaatg cagagatggt caaattcaaa tcttttttag ttctttgtag ttaacgatta
    34741 ctacaccctt actttgcgtc atcaagttcg cattttctgc agtttcatca atctcaacaa
    34801 cagcggaatt tttcaattgc tttgaaatcg ttccagtttg cgacttgccg tgaattgtga
    34861 acattacgtg agtattgatc ttgaattttt caccaatttc cgatggtacg atagttgtat
    34921 caaattttcc aaaagttgcc attttcataa aacctgcctt tcacatcaat tataccacgt
    34981 tttatgaaaa atatcatgaa attaaactaa ttttccatcg gactctttac aatcagccaa
    35041 atagagtata taatttcttt tggataaggc cagcttagct cagttggtag agcaacgcac
    35101 tcgtaacgcg taggtcgtag gttcgatccc tatagctggc attaaaagag aagacagata
    35161 tatcaaggat ttttaatcca ttgatacatc tgtctttttg tttaaaggaa ataaagtatg
    35221 ctttcttagc aatagagcat gtattatttc tataaaaatt taggagaata aaacgactag
    35281 caatatagct gtgaaatcaa atatcacatg aactgcccaa cttgtaatga tcgagttgct
    35341 tttaatggca gcttggttga ataacaatct tgccacccct tgtatcaaaa ggatgtgtgc
    35401 tacagtgtgt aaaatatttc cattatcata agtactgtaa tggataaatc caaagatgat
    35461 tgctgacaag aaactagcga caggaatgct gaacttacta gaaaaaatag cgagaaaata
    35521 cactgagaac aattcttctc caagtatcat gataggcaaa ataataaata ataacgggct
    35581 gaaagcctca tttattggat tgcctgttaa accccatttc aaaatttgtt gcaaaaatac
    35641 cgagactgcg gcactgatta ctacattgat aaaaaaatat ttggctatat ttttgacagg
    35701 agcgacaggt ttcgagaaca tttttttcgt atctttttta ccaaaaacaa gtgtaaatgc
    35761 tataaatcca gtgatagtta aagaaaaaat gctaataatg gatggcgcaa atagcaaccc
    35821 taacaaaccg agtacaacga caatagtgcc caatatccct tttttaagtt ctattttttt
    35881 tcctaaaatg ttattcatga taataactcc tactattcag tttttgaaga tagagtcagt
    35941 atacatgaag agttaaaata ggcaatgttt ttttatggat atttgtattg ctaaaaattt
    36001 atcttatata ttcattttga ttatactact tttatttgta aaaattttct agcaaaacca
    36061 agtgcttgca actgattaag cgtacaattt tttagatgtt ccgagcgtac ttcaatcatt
    36121 tcaaaggagt tgctacttaa atcgatattt tttaaatcag tatcaaaaaa gctagcattt
    36181 tctaaatcat tagtagaaaa cattatttta gtgagggaac agtctacaaa atctgcgctt
    36241 gataagacag agtgctcaaa ggtactttct tttatgtttg aaccagataa atttacatag
    36301 tccattttac aattctcgaa taacgtgttc ccaatataac tttccatcaa tttagtacct
    36361 gttaatttac aattgacaaa tttcacgcga tgcaacatgc tttttgtcaa tatacagcct
    36421 gaaaaatcac agttttcgaa tatacagtcg gtaatctcca ttctttgaaa atcattggaa
    36481 gcaaaaaatg catacttgaa aatagatttg taaataattg gatggcagat tatttggttt
    36541 tcgatgacct ctttttgtga aaggatatta tacagttcaa aatcttcgtt ttcatagata
    36601 tgaaaaaagg atcctttatt caagcttgct tcattaactt taggaaaaat catatttaat
    36661 tacctccatt ttcataaagt catattaaca aaagctaaac caacttacat tagcagaaaa
    36721 tgagataggt tttcgccttt ttcgataacg atagtgtcgc tatctcttga aacgttctta
    36781 gaattgccct gagagacaca aattaggcgt aattctaata aaaatcttag aataaaaatt
    36841 tttactgatt taatttagaa tgtttttaaa ataaaaatcg ttgccataac agtgtattga
    36901 aaggttttaa caatccagta atgatttaaa aaaatctaga tgtagcgtat actttgttta
    36961 tagaatgtag tgggaagaaa tatatttttg ggaggaaatc gtgatgtcta aaagtgaaga
    37021 aatagaaaac atggtactaa aattatatga tctcgtttta aatccagaga tcaaagaaaa
    37081 ggaacgtata cttttgatag acgcaaagac aggcttagaa aaaggtcagt attatcctaa
    37141 agtcataaat aatttggaac gtagtttacg tccgttagca atcaggggag aattgtctaa
    37201 accagtatca ccgttttata tggagatatc aacaatagga aaatttgaaa aagaattagg
    37261 tcgaggaatg gcttcggcac cgattacttt tgggcattta taaaaacgag ttattcatct
    37321 caatgaatta aaaagtatag tcaatctcat aatgcaggct aggttcattt atttgaacag
    37381 agtctgtatt tttttattct aaataaagaa acagatgttt ctttatattg tattttatcc
    37441 tttaattaac acaaaaacag ctagtataaa ctaataatgt taattaaaag tgtattttat
    37501 gaaactatcg ttatttatta atgttgcatt tttgtaagtt aaaaattgga aatatagatt
    37561 gaaaaaatga aagcaataag taaaataaaa tgaatatatg cgaaaaaata atttacatta
    37621 ggaaaaacct tgtaaaaaca gttttttggc atatttattt tttataaata tttgtaaaat
    37681 aactatcaat tttttagtta aaagattgga aatgagtggg ggaggaattg aagaaaggat
    37741 ttttgagaga tgat
//
LOCUS       DAFEIE010000024        36898 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFEIE010000024
VERSION     DAFEIE010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.024"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..230
                     /locus_tag="LP345_001324"
     CDS             <1..230
                     /locus_tag="LP345_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBL1760112.1"
                     /translation="TVEQFCELYAYPQGTVASWITRQRRIKSLPASFVYDLSLASSMN
                     MTDVYEKLLILENEYDQFNSNQQRKVKKQID"
     gene            456..1274
                     /locus_tag="LP345_001325"
     CDS             456..1274
                     /locus_tag="LP345_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1760113.1"
                     /translation="MDTFQGTTFTVGNFKGGVGKTKIVSMLAYDNAMIRNRKTLIIDL
                     DPQANLTQVIARTFGITDIKTTITNGVANGELASSIIKVNENLDLLACDTSFRSFSAF
                     ANKHENELDQVTVLKKLLLPIKNNYQEIFIDVPPTISEFSDNAMAASDYSIISFQTAE
                     ESLEGVNKYVNYQKFMVDRYDLDLQIIDIVPCMVEPNDDFDEEILEEAIEKYGTVVSK
                     NLIHYQKRLRRYSKIGIHLRKYKNGNFDQWDYKAHQVFINILAELDARQEFLNK"
     gene            1293..1700
                     /locus_tag="LP345_001326"
     CDS             1293..1700
                     /locus_tag="LP345_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760114.1"
                     /translation="MPKDFDIPKMMENGEFEPLLPNNKRQDVKISGEYNFSNSALSNT
                     RNITLKKRGRPVSIPDKRNKVSVPKKISPALNSKLSILQDYMTELQSEKGRISFEKIV
                     NTLADSYIQHRLGVAKEEHIREEIQEEFEKLPK"
     gene            2020..3105
                     /locus_tag="LP345_001327"
     CDS             2020..3105
                     /locus_tag="LP345_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1760115.1"
                     /translation="MSTENQSQKMIIKNWGYKATNVYIEKYYKFPSFLIQNSKYSKMK
                     DSSKIAYMLFKNEFRRALHEKWIDDDGLLYLEFTQADLMDKLNCYQGKVKTILNELET
                     YNLISVVKGEFNPKTKKNEKNKYYLLQPEISADDLFIQNSFDDDLSETIDKSTSSRNA
                     EIARREETAKTLDNTGNAEIARREKTAETLDNTGNAEIAQDYYINKSLDTKRHLKDTE
                     TDQLQNQVLLDNFVEIMKEDSINTFVPEKVLSLIKTFSNTYEEAQQTVTTIHKAKHKA
                     EELEKTVVVYEELESYGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFIEK
                     AIAAKLANEQRETFNELPTVSTENWLE"
     gene            3942..4274
                     /locus_tag="LP345_001328"
     CDS             3942..4274
                     /locus_tag="LP345_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBL1760116.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            4865..5194
                     /locus_tag="LP345_001329"
     CDS             4865..5194
                     /locus_tag="LP345_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760117.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            5181..5522
                     /locus_tag="LP345_001330"
     CDS             5181..5522
                     /locus_tag="LP345_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBL1760118.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLTDDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            5636..5875
                     /locus_tag="LP345_001331"
     CDS             5636..5875
                     /locus_tag="LP345_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760119.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPTRPVIKRKKKITQD"
     gene            5942..6181
                     /locus_tag="LP345_001332"
     CDS             5942..6181
                     /locus_tag="LP345_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760120.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMKIT
                     GKEKACLLGSMKNFEQLRRTYVKTGSNCQLLLEVS"
     gene            6308..6997
                     /locus_tag="LP345_001333"
     CDS             6308..6997
                     /locus_tag="LP345_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HBL1760121.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDGVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYLDTEMGNGNYILAGYNVDTPSVLLSDMTDLSEGEEIDLIDA
                     HYKYQYEVSKRGKISDYSQVVQSKENNSFLSLPKAGKKPLLTLLAFQANNMKKCDVIQ
                     CELVNVEKINK"
     gene            7003..8169
                     /locus_tag="LP345_001334"
     CDS             7003..8169
                     /locus_tag="LP345_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBL1760122.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTKFTVIDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFIILEILPKKVFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFVLSIILLLSFLWLL
                     VRKRELTNGQLTFLWAFLAIMCQSFMEETLTTISWVPIVFLMLAMATHQYKTTR"
     gene            8251..8922
                     /locus_tag="LP345_001335"
     CDS             8251..8922
                     /locus_tag="LP345_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL1760123.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            8975..10951
                     /locus_tag="LP345_001336"
     CDS             8975..10951
                     /locus_tag="LP345_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1760124.1"
                     /translation="MAINRYVKKAGMIVGMLGIIAGCFQGYRAYAEDVTQKTPPERVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGELVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGEEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            10964..11716
                     /locus_tag="LP345_001337"
     CDS             10964..11716
                     /locus_tag="LP345_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1760125.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            11732..12493
                     /locus_tag="LP345_001338"
     CDS             11732..12493
                     /locus_tag="LP345_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760126.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            12506..12766
                     /locus_tag="LP345_001339"
     CDS             12506..12766
                     /locus_tag="LP345_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760127.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            12763..14853
                     /locus_tag="LP345_001340"
     CDS             12763..14853
                     /locus_tag="LP345_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1760128.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTILAVSLLL
                     LVLATFGYAVLKFN"
     gene            complement(14889..16946)
                     /locus_tag="LP345_001341"
     CDS             complement(14889..16946)
                     /locus_tag="LP345_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBL1760129.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(17091..17282)
                     /locus_tag="LP345_001342"
     CDS             complement(17091..17282)
                     /locus_tag="LP345_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760130.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            17470..17925
                     /locus_tag="LP345_001343"
     CDS             17470..17925
                     /locus_tag="LP345_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760131.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVSYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            17922..18164
                     /locus_tag="LP345_001344"
     CDS             17922..18164
                     /locus_tag="LP345_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBL1760132.1"
                     /translation="MIASLFIYPEGGIAVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            18182..18484
                     /locus_tag="LP345_001345"
     CDS             18182..18484
                     /locus_tag="LP345_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760133.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQGAATSLKNNLMIFAAVAA
                     VASIVLGGIFFFFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGMFGQTPQGL"
     gene            18553..20607
                     /locus_tag="LP345_001346"
     CDS             18553..20607
                     /locus_tag="LP345_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760134.1"
                     /translation="MYFTISGNTKKDKELIKKATKKVGKRTAFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVSQVSEVEVNDEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDLVEA
                     NEEPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWERTKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCIE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMERHGQIQQELQAQIPKWKKEYEIQQQELKEQEEKQRQEEKEREQLELKKREQH
                     LAEQKVAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTAESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            20607..23219
                     /locus_tag="LP345_001347"
     CDS             20607..23219
                     /locus_tag="LP345_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBL1760135.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGSFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            23216..25594
                     /locus_tag="LP345_001348"
     CDS             23216..25594
                     /locus_tag="LP345_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760136.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            25655..26197
                     /locus_tag="LP345_001349"
     CDS             25655..26197
                     /locus_tag="LP345_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760137.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            26275..26607
                     /locus_tag="LP345_001350"
     CDS             26275..26607
                     /locus_tag="LP345_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760138.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            26608..27201
                     /locus_tag="LP345_001351"
     CDS             26608..27201
                     /locus_tag="LP345_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760139.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            27223..29247
                     /locus_tag="LP345_001352"
     CDS             27223..29247
                     /locus_tag="LP345_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBL1760140.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            29247..30446
                     /locus_tag="LP345_001353"
     CDS             29247..30446
                     /locus_tag="LP345_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL1760141.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            30462..31106
                     /locus_tag="LP345_001354"
     CDS             30462..31106
                     /locus_tag="LP345_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760142.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPVDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            31117..31923
                     /locus_tag="LP345_001355"
     CDS             31117..31923
                     /locus_tag="LP345_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760143.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIFYIH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVAEDQENTENKINSYQQEIETSKTQMKDQEESIQKLQEKIDRMTKENI"
     gene            31946..32175
                     /locus_tag="LP345_001356"
                     /pseudo
     CDS             31946..32175
                     /locus_tag="LP345_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            32196..33269
                     /locus_tag="LP345_001357"
     CDS             32196..33269
                     /locus_tag="LP345_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4199 domain-containing protein"
                     /protein_id="HBL1760144.1"
                     /translation="MKKTYQKFLWISYIVLFIVGFLVSVSVIVGTLFLLFSDEDLVLK
                     GLMSTLSCVMLLYLCIQINEIMPPHWQEKKKEFKEEIEIKSNDWIEYTWLPLKRNSKR
                     KEFWALQLWPIGKLFIYMASLMVTLIGYLVVVYGVAYYLLSEPKQIAASNIFTAVMTL
                     MCVMCFSIFSYLLVQFIRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIK
                     NFLTTIDQFINGYMYLFEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVD
                     FGKYEELIHTDIVHTSIHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGI
                     GKLRLDGSNIQQNKPYVLGKVVI"
     gene            33313..33582
                     /locus_tag="LP345_001358"
     CDS             33313..33582
                     /locus_tag="LP345_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760145.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            33858..34133
                     /locus_tag="LP345_001359"
     CDS             33858..34133
                     /locus_tag="LP345_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760146.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            34175..34597
                     /locus_tag="LP345_001360"
     CDS             34175..34597
                     /locus_tag="LP345_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760147.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
     gene            34617..36209
                     /locus_tag="LP345_001361"
     CDS             34617..36209
                     /locus_tag="LP345_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760148.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            36230..36565
                     /locus_tag="LP345_001362"
     CDS             36230..36565
                     /locus_tag="LP345_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760149.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            36711..>36898
                     /locus_tag="LP345_001363"
     CDS             36711..>36898
                     /locus_tag="LP345_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760150.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        13403 a         5628 c         7367 g        10500 t
ORIGIN      
        1 tcactgtaga acaattttgt gagttatatg cctacccaca aggaacggtt gcaagctgga
       61 taacccgaca acgtagaata aaatcattac ctgcttcatt tgtatatgat ctaagtcttg
      121 cttctagtat gaatatgacc gatgtatacg aaaagttatt aatactagaa aatgaatatg
      181 atcaattcaa ttcaaatcag cagcgaaaag taaagaaaca gatagactag aatagctatt
      241 ttcgaaaagc aatatttaag gtataagtta tacctttaat aataaaagta taagttatac
      301 cataaatata tatggtataa cttatacttt tattattaaa aaccgctata tccaaacgtt
      361 tttagatatt attatttaag ttatactttt aatgttgacc atttccgata tataagttat
      421 actttaatta tcaattaaag attgggagga tttacatgga tacttttcaa gggactacat
      481 ttacagttgg caattttaaa ggaggagtag gtaaaactaa gatagtcagc atgcttgctt
      541 atgacaatgc aatgataaga aatagaaaaa cgcttattat tgatttagac cctcaagcga
      601 acttaacaca agtcatagca agaactttcg gtataaccga tatcaaaacc actataacaa
      661 atggtgtcgc aaatggagaa ttagcaagta gtattattaa ggtaaatgaa aatcttgacc
      721 ttctggcatg tgacactagt tttcgatcat tctccgcttt tgctaataaa catgaaaatg
      781 aattagacca agttactgtc ttgaaaaaat tacttcttcc aataaagaac aattatcaag
      841 aaatatttat tgatgtacca ccaaccatta gcgaattttc cgataatgct atggcagctt
      901 cagactattc gataatttca tttcaaacag ctgaagaatc cttagaggga gtcaacaaat
      961 atgtaaatta tcaaaaattc atggtcgata gatacgatct tgatttgcaa attatagata
     1021 ttgtaccttg tatggtagaa ccaaatgatg attttgatga agaaatccta gaagaagcaa
     1081 ttgaaaaata cggaaccgtg gtatccaaaa atctcattca ttatcaaaaa agattgagaa
     1141 ggtattctaa aattggtata catttaagaa aatacaaaaa tggaaatttt gatcaatggg
     1201 attataaagc acaccaagta tttataaata ttttggcaga actagatgct agacaagagt
     1261 ttttaaataa ataataagga gttgcataag taatgcctaa agattttgat attcctaaaa
     1321 tgatggagaa tggtgaattt gagccattat tacccaataa caaacgccaa gatgtgaaaa
     1381 taagcggtga atataacttt agcaatagtg cattgagtaa cacaagaaat attacattga
     1441 aaaaaagagg ccgaccagtt tcaattcctg ataaaagaaa caaggtatca gttcctaaaa
     1501 agatctctcc ggcattaaat agcaaactct caattttaca agactatatg acggagttac
     1561 aaagtgaaaa agggagaatt tctttcgaaa aaattgttaa tacattagca gactcatata
     1621 tccagcatag actaggagta gcaaaagaag aacacataag agaagaaata caagaagagt
     1681 ttgaaaaatt accaaaataa ttttttttca tgcggtattc aattaaagta taagttatac
     1741 tagataaatg aatattaaag tataagttat acattaaata tttaaggtat aacttaataa
     1801 acaacgtgta aatttgcgat taaatcaaca ttataaaatt attatttaaa gtataagtta
     1861 tacattattt gtatttaaag tataacttat acttattttt ttaatatata acttatacct
     1921 taaatactga aagtgtttta ttcaccctta atacatggta tagttcactt gttgaaaatc
     1981 ctgaatatat acaagtttct aagaagaagg agaaatttaa tgtctacaga aaatcaatct
     2041 caaaaaatga taattaaaaa ttggggatat aaagcaacga atgtttatat tgaaaaatat
     2101 tataaatttc ctagtttttt aattcagaat tctaaatact ctaaaatgaa agacagctca
     2161 aaaatagcct atatgctttt taaaaatgaa tttcgtagag ccttacatga aaaatggatc
     2221 gacgatgatg gtctattata tttggaattt acacaagcag acctaatgga caaattaaat
     2281 tgctaccaag gcaaagtaaa aaccatttta aacgagttag aaacatataa tttgatttca
     2341 gtcgtaaaag gagaatttaa cccaaaaacg aaaaaaaatg aaaaaaataa atactattta
     2401 cttcaacctg aaataagtgc cgatgatctt tttattcaaa attctttcga tgacgattta
     2461 agcgaaacta ttgataaatc aacctcttct cggaatgcgg aaatcgcacg tcgagaggaa
     2521 actgctaaaa cccttgataa cactggaaat gcggaaatcg cacgtcgaga aaaaacagct
     2581 gaaacccttg ataacactgg aaatgcggaa atcgcacaag attattatat taataaatct
     2641 ttagacacta aaagacactt aaaagacact gaaacagacc aattacaaaa tcaagttttg
     2701 ctagataact tcgttgaaat catgaaagaa gacagcataa acacatttgt accagaaaag
     2761 gtattaagct tgataaaaac attttctaac acttacgaag aagcccaaca aaccgtcacc
     2821 acaatacaca aagcaaaaca taaagccgag gaacttgaga agacggtagt tgtgtatgaa
     2881 gaacttgaat cttacggaat tgatgcggat aaaggattat atatgacgtt gctgaaagct
     2941 tatcaaaaac aaaagactga gaaagtaaat aatttgcaga atttgatttt tgtgtatgta
     3001 aaaaactggt ttattgaaaa agctattgcg gcaaagcttg caaacgaaca aagagaaaca
     3061 tttaacgaat taccaacagt tagtacggaa aattggctag agtagttgat aaaaagcgaa
     3121 cactataaaa atgatcaatt ttaaattaga acttttttac aattttaatt ttattacaaa
     3181 tgttacaaat aaatagttat tattccggag tttttagatt aaaagtttat gaaaacaatc
     3241 acaaacgtag gttttaatgt cataatcgtt agatatttta gttatttttc attcaaaaaa
     3301 acagggaact agtgtttgca tatgtatttt tttgagttat aataattcat gaagagaggt
     3361 aattcactta tttacccaag ctgaaaagcc tgatattact tcttttcagg cagtgctgct
     3421 aatattcaat tacacttttt tgtataaatt tagttgtttt aaatttaatt gtctgctatg
     3481 cttgtgatga attgattttc gttctgcact tttggacgat aaatttggac aattgaaaat
     3541 acaaaaaaaa gaaaggccct gtgagactcg gaaggctacc aaccttcgtc gacgtccaca
     3601 ggtggcatta agtctatacc ccttaatgcg tttacctttc agtgttacgg tattacccgt
     3661 aacggattta gtataacaga tattcaaaag tgataccact ttttttggct gtgttaaggt
     3721 taaaaatacg tgatattacg atgaatctat gcctaagcat aatgttataa aaatgtccgt
     3781 ggggctcttt gccgtatgac gaacgctgaa attagaggga acgcatgttt gaatgcgttc
     3841 cctctttttt gtttgtcatg aacgaaaatc aattctctat ttttgaaaaa taacaagaaa
     3901 aacttgttaa aaatatttaa agtaagtggg tggattattt tatgtcatat acaggaattt
     3961 tgagtctcga agatatttgt cactacggta aacggtgtac cgctacagaa aagatcacga
     4021 agaaactatc aactggtcaa agtaaaaccg ttgtgcagtg taagaaatat ataatccaga
     4081 aagacaaagt ctcagaagaa atgatttatt acattgggaa acaaaaacaa ataattttaa
     4141 aagatcctat ccctttaaaa gagctatatc caacaatcaa acatgtttat gaccaaaacg
     4201 gtgtactgat tggtcgaaga aaaaatggag tcttgcgttg taccgcaaaa gggatggggc
     4261 gtttaatcag ctgaattgat cattctcata acttgtattt tatcgttttt cgcttgcttg
     4321 aaaatattgt cgagacttct aaaggaactt agaatcacta gaaaaataag gagtagactt
     4381 gatctatcaa caattccctt cggggagtga cggggtaggt ttttacgatt ggtaacgtaa
     4441 aaaattggtc aatcgagtaa atgcccttgt ttggatagtg gtgaaatgaa tttgtgtaaa
     4501 taatatgcac agagtaaaca agagggaatt tagaagttag acaagttaga atagcgccta
     4561 gattaatcat gagcagctac taagggatct aggctttgac gcaaactcat ggaataagga
     4621 gtaggtcttc tcgtaatggg gaggacgcac aagaaattgt gtcgtgtgct gcagtacatg
     4681 tagatacttg cgaggacgtt gatcattgga tcaatcgagc atttaccgct gtctactagg
     4741 gtttctcgtt tcggacgcca taaacgagtc gatttatttt atatattttt gagtgaacga
     4801 aaaacgataa agatattcgt tatgaagtaa aactaattta gtagatagca aaggtggtag
     4861 aggaatgatt caaaaatttg cgaaaatgag taaaactgca tggattgaaa agcttgaaaa
     4921 tgacttgagt gtcatgcgat tagctccaaa gaaattcaaa cgagagattg cagaaaaaga
     4981 agcaattttg tcggtattga atgcggtaga cgataaatgt ccagtaaaaa ttagtttttc
     5041 agatatagca acaattatcg aaggtattta ttatggtgaa gttgatgaag agatatcttc
     5101 tacaaaagat ttattagatt ttttggataa aaacaaagat acctttatag tactaactga
     5161 ttatgaggag gttacaacaa atgaaaaatt atgatccgaa tatacgattg ggcacacata
     5221 cgattaaggt ttctttccaa cgttgggatt acaaaggatt tgtgacgttt agaagaggcg
     5281 gaaattgtaa aggattagat gttttagcat tagacgagga tgatttatac gatcaaacat
     5341 tgactgataa tccaattgga ttcggcttgc tacctgaaga tgatgaaggt aatgaatggt
     5401 ttaaaatgac gcttacggat gataatggag acgaattatc tgttgaagat acttggtcat
     5461 atttgagtga ttatattgtc agcgttgaaa tcattgaatt tgtagcggat aaagaagaat
     5521 aaaaactgga ggaataaatt ttacagataa aggcttagaa ggagtcacga cgaataataa
     5581 aaaggtagta ttaccttagg cattgagtaa ggaatttatt taggaggaaa attagatggc
     5641 gcgaccagtt ttagaggcga tggatatgga tactttgaca aaaggaaggt atgtacagct
     5701 gttagctcgt ggttattcac ctaaagatgt attcaaatcc ctgtctaaag gaacagatat
     5761 ggaaaaagaa agattacgaa aagaattcga ttattggaga acccataatg gaatcaagga
     5821 tttgaaacca acacggccag taattaaacg aaagaaaaag ataacccaag actgaagtgt
     5881 agagcgtatg tgatcatagg cttttttatt tttgcaaaaa acaagaaagg taggaaaact
     5941 catgaattat gaagaaatcg aaaacagaaa aaaagtgtcg aaagaaatgg aagaaaagtt
     6001 gctaaaaatg atgaaacaaa aacaccttaa aagattatct gtcatgcaat atatcaatga
     6061 tatgaagata acaggaaaag agaaagcttg tttgttaggt tcaatgaaaa actttgaaca
     6121 gttgaggcga acttatgtaa aaacaggttc caattgccaa ctattattag aagtttcttg
     6181 acgattatga tatgaaaatg atcaattatg atgtggcatt gttattgaat aaaaagaata
     6241 gtaaaattta acatggttta tcttggttag atgtaggtaa attaattcat atatagaagg
     6301 tagatagatg aataaaaaca ataaaacttt atttaatcct tacgtgggcg taatcattgt
     6361 ttttcttctt tttagttatt ttgcttatca aggttatcaa aaggacaaaa tcgctgaaaa
     6421 agtagatggt gtaacaaaaa caatccatat tcaggaacag gctaaaacct atcaagataa
     6481 tttaaccagt ttaacggata tttctaagag acaactgatt actaatcaaa aacaggcatt
     6541 agaaaaggat ctcaaaggtg aaattgctgg aaaacttgtt ttttcttcta caggatttat
     6601 tctccctgtt tttcaaggag cgaatagcga cacgcttagt ttaggagtag cttctactta
     6661 ttatctagat actgaaatgg gaaatggaaa ttatattctt gctggttata acgtagatac
     6721 accaagcgtt ttattatccg atatgactga tttatctgaa ggagaagaaa ttgatctaat
     6781 cgatgctcat tacaagtatc agtatgaagt ctccaaaaga ggaaaaattt ctgattacag
     6841 ccaggtagtt caatctaagg aaaacaattc ctttttatcc ttgccaaaag caggtaaaaa
     6901 accactactc acactgttag cctttcaagc aaataatatg aaaaagtgcg atgtgatcca
     6961 gtgtgaatta gtcaatgtag aaaaaatcaa taaataaggg aagtgagtca cattcaagaa
     7021 cttgtagaaa aattgatcaa taaaatgagt gccatttttc tgttactgtt ggtatccatt
     7081 ctatatttaa tatggacggt ggggttaaat cctcctacga tattatttat ttatgataat
     7141 gctgcacagt tagtgacgtt tttcgtaggc tgtttgtttc ttttgaatct gtacaaggta
     7201 aagagaaacg atctattctt cattgcagca ggcattcttt tttacctttt cttttctttt
     7261 tttagaagct accgaggaga tactttctat ggtgatctga tcgttccgac aattattgct
     7321 attattttga ttgtaaaatg gacgaaattt actgtaattg atcgtagctt gtatcttgta
     7381 gtattctatg tctttttact cgtaacggtt tatcgagtat ttactgagat accagtacca
     7441 gaaggacaaa gtatttggaa tccatcgaac aaattatcag atatttggat caatacaaat
     7501 acgataggta gttctttaat gacattagcc cttcttatca caggatttgc tagttcattt
     7561 ggaaaatggt acatgcgatt gctatcatta ccagcgttga ttcttgctgg ggcaacgatt
     7621 tgggtttgcc aatcgaaagc agcattatat gcgcttgtta tcttcattat cttagaaatt
     7681 ttacctaaga aggtttttcg aaatacacac ttgtcctttt ggatgtatgc agcagtttcg
     7741 gttctagctt taccgatttc ttattttgct gcaatgtcag acaaagttca cttatttaca
     7801 ggacgagaag aaatttggcg caaattctat gaaacattag gcgaaaaaac aggacaaata
     7861 tttgtaggga tgaaaccttt ctttttccat agaggaaatc agattctagg taatcataat
     7921 acgtatcacg cactcgtcaa tcactatgga ttgattggtt ttgttctatc gattattctt
     7981 ttgcttagtt tcttatggtt gctcgtaaga aaacgtgagc tgacaaatgg acaactaaca
     8041 ttcttgtggg cttttttagc gatcatgtgt caatcgttca tggaagaaac attaacgaca
     8101 atcagttggg tgccaattgt attcttaatg ttagcaatgg ctacacacca atataaaacc
     8161 accagataaa tgaaatagaa tagtaataag agaaaacact ttttcgttgt gaaaaagtgt
     8221 tttttgtttt gtctgaaagg aggcagatgg atgaaaaaat ggttatttgg ttttttagga
     8281 gtcgctttaa tcgtcgtttg cagtgtgttt ggctatgtta gctaccaaaa acatgaagga
     8341 gaggtgttta agcaaaatat agaaaaaaag atgcccgtag atcaaatcaa tgcacacgca
     8401 aagagttata aggaggatgc aacgaacgtc aataatgata tgtctttggg gcaaatgttg
     8461 tccatacaaa aagaagcaat cgaaatgggc gtcaataaac aagtatttgc acaaattcag
     8521 attcctgcac ttggtttagc attgccaatt tttaaagggg caaatcaata cactttgagt
     8581 cttggagcgg ctacttattt ttatgaagat gccgaaatgg gtaaaggaaa ctatgtccta
     8641 gcaggtcata acatggaaat gccaggtgtt ttattttctg atattcaaaa gttgtcatta
     8701 ggggaggtga tggacttagt tagtaacgat ggcgtctatc gttacaaggt aacgcgtaaa
     8761 tttatcgtac ctgagtactt taaattaatc gatggcgttc ctgaagagaa ctctttcttg
     8821 tctttaccaa agaaaggaga gaaaccctta ttaacgttgt ttacttgtgt ttatacgtca
     8881 caaggaaaag aaagatacgt ggtacaggga gagctacaat aacaagaatt taatcaacgc
     8941 gagtcgttga aatatgaaat gaggagagta aaaaatggca ataaatcggt atgtaaaaaa
     9001 agctggaatg attgttggaa tgttaggaat cattgcaggc tgctttcagg ggtatcgagc
     9061 ttatgcagaa gatgtcacgc aaaaaacgcc accagaaagg gtcaatatca cggttcataa
     9121 attaatgtac gatcaaagta cgcaattgaa cgttgatatt gacggaatca aaaatgatgg
     9181 ttatacgcac gatcaatatc ctacaggtgt aacgaaatac aacaaggcag attatggtga
     9241 tgttgagttt acgttaggaa atattacgga tcaagtatta ccgactgaag attctgatct
     9301 aaccaacgcg aaagtggacg aaatcgttaa agatgtagaa gacaagggat ctaacagtga
     9361 gtacgttaag aatgcaacca ataaaattac ttcagctgta gatgaaaatg gtgagatcac
     9421 ttttgctgat caaccagcct atgtcaattc caaagggaat gtatatgtgg tttatgaaag
     9481 taaatccgct gctggattag tcacacaaaa agcaaaacca atggttgtga ttgcgccaat
     9541 gacagacaac acaggatcag gatttttaaa agatattcat ttgtatccaa agaacattgt
     9601 ttctaagttg agttttgaat taacgaaatt tggtgacgat ggcacagctc aaagcaaaca
     9661 aacaccttta aaaggggcaa aatttgagtt atacaagggc gaacctggaa aaggaacaaa
     9721 attaggagag cttgtatcgg atgatcaagg aaagctgact gcaactgatt tgacgttagg
     9781 aaaatactac tttgtggaag ttccttcaga agttgtagtt ggatcagatc aagaaccaac
     9841 agcagaccaa tatttgttag gcgcagacgc tcgcaacgat gcgcacaata agttaacctt
     9901 tgaaattacg aatgacggcg tgacaagtga tttaaaagct tcctacgtga actataaagc
     9961 accagtgatc gataaaacag tgacaaatgg aacaggagaa gaacattctt tccaaattgg
    10021 tgacgcagtg aattatcaag gtacaattca tatccctaca gatatcgcag gtggaacaga
    10081 tgggattaca gtaaatggtg taaaaagtga aacttctcct tacagtgtat ttaaatgggg
    10141 cgacacagca ggtaaaggac tttcttatgt tgctgaaaaa gcagatatta aagtaacaaa
    10201 taatgatggt tcagtcgtat taaaagaaaa tactgactat aaaatcgaaa attctgatag
    10261 tggttttgtg atcgatttta tcgtaaataa tggacaagta agtgatacag ttgcgaattt
    10321 acatggtcaa gatctaaaaa tgacttataa catgtttgtg aatgatagtg ctgaaatcgc
    10381 aaatccatta acaaatagcg tggatttcgt ttataacaat aatccattta atcaggaaga
    10441 acaccacgaa aaaacgaaag ctgacgttgt gacttatggc gcaaaattct taaaagtcga
    10501 tagcggccta tttggaacag gtatcaaagc aacaccgctt gaaggcgcag aatttgcagc
    10561 taagaatgca gaaggtaagt actacggtgg acttactgat acagataaag atggtgtcaa
    10621 agaagcagtt tgggtagacg atgtagcaaa tgcagcaatc ctaaaatcag ataaagaggg
    10681 tcattttgaa atcactggtt taactgaagg agattactca ctggaagaaa caaaagctcc
    10741 tgaaaactat caaaaattaa caaaagagat ctctttcaaa gtagacaaag attcatacaa
    10801 agaagaaaac cgaatcacga tcaaaaataa tcaaaaagct tccgtaccaa tgactggtag
    10861 caacggtttc caatcttacg tattgatctc ttgcttgttg cttggggcag gcgcaatttc
    10921 tgcagttgtt tactttaaga agaaagccta gaaggatcag ctaatgatta tcagacaccc
    10981 taagaaaaag cgaatcatgg gtaaatggat cattgctttc tggttacttt cagctgttgg
    11041 tgtcttactt ttgatgcctg ctgaagcgag cgtggcgaaa taccaacaaa atcagcagat
    11101 tgccgcaatc gatcgaacag gaacggcagc agaaacggat tcttctttgg atgttgctaa
    11161 gattgagtta ggcgatcctg ttggtattct tacaattcca agtatttctt taaaactacc
    11221 aatttatgac ggaacttccg acaaaatttt agagaatggt gtagggatta cggaaggaac
    11281 tggcgatatt acaggaggaa acggtaaaaa tcctttaatc gcagggcaca gtggacttta
    11341 taaagataat cttttcgatg atttgccttc agttaaaaag ggagaaaagt tttatatcaa
    11401 agttgatggt gagcagcacg cttatcaaat cgatcggatt gaggaagtgc aaaaagacga
    11461 actacaaaga aactttgtca cttacttaga accaaatccc aatgaagatc gagtaacgct
    11521 aatgacatgt acgcctaagg ggatcaacac acaccgtttc ctagtgtatg ggaagcgagt
    11581 aacctttaca aaatcagaat taaaagatga agaaaataag aaacaaaaat tatcttggaa
    11641 atggctttta ggaagtactg tttttctttc agtcatgatc attggttcgc tatttgttta
    11701 taaaaagaaa aaataaagga gggtaaccaa catgagaaat agaaaatggc tatttgtttg
    11761 tgcagccgct cttttttctt tcactgccta cacacagttg acgtttgcag acagacaaga
    11821 aagcacggat agcacagaac aaacaatcca aacgtcagat agcagcacga ttcaaagcag
    11881 cgatgaaacc gtcgattcgt caacagttga ttcttcagaa gaacctaaaa ttgctgaaga
    11941 cgatcaaata gtcaaacaga ccattcacgt tcaaaaaatt atttcttccg aacaattaga
    12001 caaccagggg caaaagcttg aaaaacaaga aggagtaaat ggcgcgaagt tttctgttta
    12061 tgatgtatcg gacattttac aaaagatgga tgttaaggat ctcactactg accaaattga
    12121 atcccaatta aaagatcgag tgaaaaaact atccagtgat caactgaagc taatttctaa
    12181 tggagaaaca aagacaattg atcaacaaac aggtgtcttt gaattctcgg tagaagtaca
    12241 ggcaaatcag aaacaagctt attatattgt caatgaatca agtcctgaaa acatttctaa
    12301 tagcgaggat attttgctat taacacctgt ttctgataaa aatggtgaat tcttaaagga
    12361 tgtgtggatt tatcctaaat cagaagcttc gcaacctaaa gaagaagtaa aaaaaatcgt
    12421 atctactggc gtaaagaaaa acttctttga gaattgttgg gattttgtta ctcacttgtt
    12481 ttctagagat taaggaagaa ataaaatgaa actgatcaaa ttattattat tcaatttttc
    12541 ttgtttaacc gcagtctttt tgtactgcgg tttattattt tctaaactat ctattttgcc
    12601 aagctaccaa ctatacctaa tgaggatttt aaacatacca gctgcttcca tgccgctaga
    12661 tattatggaa aagctcatta ggaatccatt atttactacg atcaatttga tcgttattgt
    12721 cggaatttca ctagtcattt ataaaaaaga ggggatgaag ggatgaattt taaacactcg
    12781 tggacaagac ggttaaaata tgtttttccc ataatgatga tgttaggtac attgtttggg
    12841 ttaaaaacag ccaatgtctt tgctgaaaaa gttattgtcg atccgtcaaa tccaatccag
    12901 aacgtaaaga ataattttat tattccaaaa gatgttccta atgcaaaaac aaatattact
    12961 gtaaacggag cgtcaaaagt ttacaaatat catgttgatg ccaacaaagg tggttttaca
    13021 gacgactacg taggattagt ggagggaaac aaaaatatac gctatccttc tttccaaaaa
    13081 gaatacggtg aaacaaacct tgttttagaa ggcgtaacaa ccaacaccaa agtcaatatt
    13141 gactatggaa aaatcggtac gtataacggg aaaaaagtca atatcaagct agttctatct
    13201 aatattcact tatactcgga tacgttgccg tggaatctac tagataacaa ctatacaaaa
    13261 actcattttc gagacgatgg ctataaaaat acgaatggtg caatgagtaa atctaaaaaa
    13321 agaacagtac tttggatctc agacaatctt ttctcaggaa ttgtttacca ttcaacacaa
    13381 atgaatgtgc agctagtagc cacatatgag gacggtagcc ccgttcaatt ttcaggagat
    13441 acatttatca gttttaactc tttgaaccct gcaggaggaa aaagcacgga tcttaaagga
    13501 gaatatgccc actatgacaa aatgaatacg acagattggt atgtcagaaa agatacggtt
    13561 ctttcagaat ttaaatcttt ctacaacaat ctgaacgtgg taggtggcca cccaggagga
    13621 agctctaagc tgacacaagc ggataatgat ttcaataatt tgcatgataa attaggagat
    13681 ccgaagtttg gtcaaggtac tgtgtccttt aaaatatctg aagcaaatcc gacgtttgtg
    13741 attggttctt ctaatgttca aacctggttt actttatctt ctgcgacaat ctttagtgtt
    13801 gttcctgatc aacctgaaaa aacaggggtt gataaaaatg gaaataacgt gaacgataaa
    13861 atgttgcaag taggagacac gattcaatat cgaatcaaac agaaggtgaa tcgattagga
    13921 gtggatttac tagcggttta cgatcgattt gagttaatcg ataatttacc aaaagaagta
    13981 aattacgtcg atgcacacgt tgaaagtggt acaaataaaa aattcgatgt atctggtgaa
    14041 gtgacctatg acaaaacaaa acaccaggta aaatatgcag cgaaagctga tacattaaaa
    14101 aatcgaatga agtataacgg cgaaacttac gaattagtga tcaatgtaaa agtcaatgaa
    14161 ttggccaatc aaaatagtgt agccaaaaat cagggaacgt cgatcattaa taaagtagaa
    14221 aaggatacaa atatcattac cgtttatttc cctaaaattc cagtgaaaga agtacaacaa
    14281 aatggaaaag atgtaaacgg acgaaatgac ggtaagaagg gtacgccgac agctccttta
    14341 aacgcaggat ctgaagtaca atatctagtc acacaaaaat ggcacacaaa aggcgtagac
    14401 gctgcgtcag atcactacaa acaatttagt attcaagatc caattgaagc tcgtttgaca
    14461 tataaagaag gttctgcgca agtaatagat aagagtaaag gaaaagatat tacttctgaa
    14521 ggcacactaa cctatgatag caattcaaga acgctgaagt gggaagcttc cgctgacttc
    14581 ttaaataaca atcttttaga tggacgagaa attcagctga tatttacagc taaaactcca
    14641 ttacaatcag aaaaaaatat tgataaccaa gccgtagtag cagtagataa tgtttctaat
    14701 aaaacaaatg ttgtgacaat tggggttgat cctaacttgc cacaagttat tgttcctaaa
    14761 acaggttcta cacatttagt aacgatttta gcggtcagct tactattact tgtgttagca
    14821 acttttggct acgcagttct gaagttcaat taaacaaaaa aacaaggctg aaaatcagcc
    14881 ttgtttttct atttgaaaat gggattggca ctaataaata cgttgtctga agaaagtgat
    14941 ccgtctgcag aaacttcata agcatgggat aaaccaacga tactttgatt gttgtaaagc
    15001 aagtttgcgt tatgagcagc gctatctttc cacataacca tagcatttac tgctcctgta
    15061 tctgaaagga tctcgtcaac gtaaaggtag aaactattga tattttctcc tttagcaccg
    15121 tagcagccta agctttctaa gagatcttgg aaagtaccgc cgccaggtcg gtaatgactg
    15181 aagcttactt gtaattcttt tgcacgaata tctgcagctt gttgaacgat atcattgaat
    15241 tgcattgggg caacgccatt ttgttgacgg tagctattta accaagcaag ttctttttga
    15301 cgcacatagt tgtttaaatc acttagtgag atatttttgt atttgaaagt gatcgttcga
    15361 ttttggtcaa cattattgat tacacgttgt ccatttttat caacggtaac agatgaatcg
    15421 tcatttctac acaagaagta gttttgatcg gtcatatttt tccaagaagt agagaaacta
    15481 tctccctcgt aaaccgtttg tgtttcagta gataaaacag cgtttgtgtc aacgtttata
    15541 tggttcacag tgacgttgta ttgatgagta taggcaaaat tgattccttg attacttgta
    15601 acgttgttta aagtcacagt gttgctagag ctttctctag gatcaagaac aaaattagtg
    15661 aacataggtg cttcaattgt gatgctttgt ccataaacga cgggataact cttactgtaa
    15721 ttatagagtt cttggatatt tggatcagta tccgagactt tatttggacg agctttcact
    15781 tcaactagaa agacttcatc atagtaaaaa gtaaatgtgg tatttgtgtt aatcgtttgt
    15841 gtttgtgttt cattcccatt tacttgatac tgtggtgctt caaagttagt caagtcggtt
    15901 ctagcttttg cagtgtaact tgtaccagct tttactgaga catgttcttc ttttagcagc
    15961 gttccagttt gtcgattcat atgacggaca gttaccgcat attctgaagg tttaggtttg
    16021 tgttgtaacc ctttaaatgc agaatcaaga ctatttttag cattatttac ttgggtttga
    16081 gaagctttag aatcgtctag tactttttta gcattggata aagcagtctg aaaattattc
    16141 caagatcctt ctgtaaaatc tcctttagca gttgatttta cttggttgta caaggcttgt
    16201 aattccgttt tgttcacagt aggagctggt tttttcttta atcccttgta agcagaatct
    16261 aatgtgtttt tggcactatc cacttgtttt tgagtcgctt ttgagtcatt taacactttt
    16321 ttagcattgt ttaaagcggt ttggaatgcg ttccaggtat tgtcggtata gtcacctttt
    16381 ttagttccct taacgctcgt ataaagagct tctaaagctg atttattcac tttgggttta
    16441 gaggtgtcag caccatacca accaatacct tcgtatttcc agccatagtc tttggttaac
    16501 cattgtactt ctttccaact tgcagtgtag tgatgcgaac cagaggtaac acctggaagg
    16561 aaaaggcggt agatcggttt attatttttt tcggcagaac gccaggcagg cccttcataa
    16621 gtccaaccgt aatttttggt caaccatttc acttcatccc aactagctgt gtaatggtga
    16681 tcacgaaggc ctttattgta taaacgatag acaaggtggc caccgctagt cggtgcttcc
    16741 caagcggggc cttcataatt accccactta attttcacta ggtgatcacg ttcttttgtg
    16801 ctagaggtgt aaaaatgttc atggttattt ggattataaa ggcgatacat gacgttagtt
    16861 gaagcagcgt cagcagatcc agcaagagca actgtggcag caaatgttcc aatagctata
    16921 acagtttttg ggtttaataa tttcatgttt tcaactccct attaaatgat taaatatttt
    16981 gtttacattc ataatatacc acggtatacc gaggtagtca acggtatacc gtggaaattt
    17041 tgaaataaaa aagccgccct atgaagagtg taaggatggc tgtttatatg ctatgaagaa
    17101 atggattcgg cgtatttggt tagtttggca gcattatcaa atcgcatttt ttcaatcgca
    17161 ctttttttct ttattaaatc cgcaattgtt gattctgcga ctgaagaatg tttgctaatt
    17221 tcatatgctg tcttgccagt ttcaaatagt aaccattcga ttttctcttt atcagcgtac
    17281 attgcaatgc tccctcttga ttttttcttt attatagctc ttttttgtaa taaatcacaa
    17341 tatcaagagg aaaagtttct atagaaaggt gggaaattat gagtatccgt tccccgtgta
    17401 tcaaaatgag gtttgttgct actttcgtta tttaatatac taaaataaaa caacgaaaga
    17461 aggaatagaa tgaaaaagtt aataatggta tttacttcgt tgattgccat gattgttatt
    17521 ttaggtggat gtggtagtga aaaaaataag caagatagtc aagataatgg cgtgttaaaa
    17581 ccaggaacag tgtggaaaga agaagtaggc ggacttgttc ataatttaaa aattatagat
    17641 gatacaacat gggaatattc cgaaagtgtt tggcatcctg aacaagtaca aataacagtt
    17701 gagaagctaa aagactataa aggattagaa agatataagg taatcgattc aggtggagta
    17761 gatttattca taggtaaaac agccttaata gtttcctata acaaagacgg tttagaaacg
    17821 tttaaattta ttccaacaaa cgaaaaagaa catcgagata aaagtgaaat attaaaagaa
    17881 tacagtacta aatctggata caagttacaa aagactagcg agtgattgct agtcttttta
    17941 tttatcctga aggaggaatc gcagtggcaa aagctaaaac gccatttgaa aaagccgcgt
    18001 ctaaaatctt agaacgtcgc ggtgtatctg aaacacagtg gaaacaagaa gtccttgaaa
    18061 aagcacaatt tgacctatta cggggaaaag acaaggactt agaaggatat atctatcaac
    18121 gtgaacgtga aaagcttgtt ttcgatgaaa ttattaaaca ctaaaaggag cgaacaattt
    18181 tatgtttgaa tcaattacaa tgaatttttt aacacaaccg aaagtagtag ctgcggttga
    18241 tatttttaga gcattacaag gtgcagcaac tagtttaaaa aacaatctga tgatttttgc
    18301 ggctgtagct gccgttgcct ccattgttct tggggggatt ttcttcttct ttggccgaag
    18361 aggagctgaa aacgggaaga tgcacgtagg ttatgtattg atgggggtag gagttatatt
    18421 agctgccgcc tctattgtgg tttcgttatt tggaatgttt ggacaaaccc cacagggact
    18481 ataaaaaata aatagaagga gtaaaaagta cgtggctact ttttactcct tttttatgaa
    18541 aggagaatac tcatgtactt tacgatttca ggcaatacca aaaaagataa agagttaata
    18601 aaaaaagcaa cgaagaaagt gggaaagcgt actgcctttt taccgaaaac aattaaatat
    18661 tctgtcattg aaacggaaga acagctacat gtgttaggac aagtgttaga acaagagaat
    18721 caatcttctg ttaaattgac tctcacgtta catgataaag aaggaaaaat agaaaaggct
    18781 ggcacagaat acgtttttgg cccactggat tatcaaattt cagaaggttt ttatcctaca
    18841 ttgatggatt tgatccgcct tgatgtgttt aaggaaacgg atgaaaccat gagtgtggaa
    18901 gagtcttatc gaaacgaaaa actgctacaa gttttagaag aagagttaga gagcgaccaa
    18961 agaaaagtga gtcaagtgag tgaagtcgaa gtaaatgatg aagtaccatg ggaacgacca
    19021 atctttccaa agaaggagtc aaaagaaaaa gagacagtct atgttgacga acaagctgat
    19081 attccgactc agaaatcgat atttgaggaa gagaacgatg taatgggtca attggaggta
    19141 gatccctttg aagaaacaat ggaggatgaa gagacggccg aagtagaagt tgatctagtt
    19201 gaagctaatg aagagccaac atggactgaa ggggattctc aggaatatat tgaaccactt
    19261 atcagtgaag aagtagagaa aaacgaaaca gagatacaaa aggcaactgt atttgattat
    19321 attttggatc aatatccgcc agagcatgaa tggatgaaag aaaaaaataa attattttta
    19381 aatgagcttt attcgaaata tcaattaccc caaacctatc aagcattttt agagagtaaa
    19441 gaagaattaa tctcacaggg taaaggcaca cttttagaac agttagagtc tgttcaatca
    19501 acaaattggc atgagcttgc acaagaagat ttattagcca cttttgaaga acgtcaacaa
    19561 gaaacagatc aagaaataaa tgagtatgcg acggaacagt catctaattg ggagagaaca
    19621 aaagaggaac taaataaaga agaacaacga gtgattgaag aagaagtaca aaaaattaaa
    19681 gagcgatacg aaaagaaacg cgacaatgcg tattccttgt gtatagagaa aattaataac
    19741 tttactaaaa ctaatcaaga agctttatcg aaagaaaaag aaaacttgtt aaaagaacgt
    19801 ataaaagaac gaaaagaaga gttctaccga ggtttacgta cagataagct aaagattagc
    19861 aaagaattaa atgaacaact gaataaactt tatcaaacaa cgactgaagt tcttatggaa
    19921 agacacgggc agatccagca agaattacaa gcacaaattc caaaatggaa aaaagagtat
    19981 gaaattcaac aacaagaatt gaaagaacaa gaagaaaaac aacgacaaga agaaaaagag
    20041 cgcgaacaat tagaactaaa aaaacgtgag cagcatcttg cagaacaaaa agtggcgata
    20101 gaaaaacaac ggttagagca agaaaaggaa aaagaagcag ctgctcgtaa ggaacgtcaa
    20161 gaacaaatgg atacattgcg acaagcacag ttgaattatc tagcacaacc tcaaccagta
    20221 gctgctgttc aaacgccagt gaacaaccaa gcaaatttaa ctccttcacc acagcgttcc
    20281 tttaacggat ggatggtggg atgtattgca agtttaagct tgcttctagg tggaggaaca
    20341 gtatttgctt ttaatcatat caatcaatct tcacaggcag attctgtagc cacaacggcg
    20401 tcaatcaagg aagaagccca ggaacaagca agaaaagagt atgaacaaca attggaagaa
    20461 ttattgaatc gtaccaatca gtcaacagca gagtcaagta tggaaaatag caaagagagt
    20521 gatcctagta aggctaaaga aggatcaagc gattcaactg tacactcaaa cacttccgaa
    20581 agttcagaat caaatgaggt gaaataatgc gtattagaga aacaacgaga cgaaaagaca
    20641 aacgattcaa tttagaaaag aataggtatc tttctcattt ctatcgctat actccttcag
    20701 gagaagagct accagaaaaa catgacaaac gtatttctca aaagattttt tatagtggct
    20761 tagcttatct tcctttaaac tatgttgtta caagaatacc agaagcattt catcgatttg
    20821 agattattcc aggaagttta caaggagtga atatttttca gttacaagaa atgccgcagt
    20881 tattccattt tgattcaact ggtttttgga atcctttgac cccaacaaca agtttaggca
    20941 cacgtttagt tgtttctacg atttgtgttg ttccagctgt acttatggga ttgaaaatgg
    21001 acatgtggtt tcgtccgcta gcagatgggc aaaaaggaga taaccgatta aaaacgttaa
    21061 aggaaatcca acaaatttat ccgcaaatac cagaatcaaa gggaagtttt cctggttatg
    21121 gcggaatacc aattactcat tataaaaaat actggtatat tcagacggat acagtaaata
    21181 cttgtattgt tggtacttcc cgctcaggga aaggccagat agaagtttta gcaaccattg
    21241 acaatttgtc gcgtgcagaa agacaaagtt caatggttgt taatgatcca aaaacagaat
    21301 tatatgttgc tagtaaagat gaactagaag ctagagggta tgatgtgtat gcctttaata
    21361 tcaccgatcc actgcaatca atgagtgata atccattggc actcattgtg aaatactgga
    21421 agcgaggaga catagacacc gcaacacagt taaccaatac ttttacgaat acgatttatt
    21481 atgatgcaaa tgcttcagac aataaatact ttaacgaaaa tgcgcagaaa gctgtcaatg
    21541 cgcttatttt tgcgttattg gaacaagcgg atcaaacagg ggattactcc aaattaacac
    21601 caaataatct cgttgaacta ctttcagaaa ttggcggttt taattattat ccagatcctg
    21661 agaatgaatt caagcagctc aatgccttag atgagttcat gaatcagtta ccccctggaa
    21721 atatagcaaa aaaacaatat ggggcaacaa aaattggatc tgataaagcg aaagggaata
    21781 tcttgtctac ggcaattaca ggattgaatc catttaccct aacgaaaatt gcgaagatga
    21841 cttctcaatc gaccattgat tacaagtcca ttggttttcc gaagtatttg gatctcaaat
    21901 tacatgaaag cctattaaat caacgcattg tcgtggaatt ttatcataag ggaaagaaat
    21961 ttcacgagga acgagtcaaa gttggctatc gtggtttttg tgaaatcaac tttgattgtc
    22021 atttagagca gggagatcat gtttgcttaa aatacaatca tcaaggaaaa caatatgttg
    22081 cttggtatga gttttctcaa aaagtattga aagacgaaga gggaaaaatc gtttatcgaa
    22141 aaaaacgagg agaaactcat ttgccagaac tagaaaaaga agccgttcta acattagatg
    22201 agaagaaaag taacctatta gtagagtcta ttcggatgca ctataccgat aaaccaatgg
    22261 ctatttttat gttaacgcct gattatgatc catctaacca tatcattgtt agcatctttc
    22321 ttagtcagtt gtataaagaa ttatctacgc aatgtgttaa gactaaagga gataaatgtc
    22381 accgtaggat tcattttatt ttagatgaat ttggaaatat gccaccgatg gacaacatgg
    22441 aaggaatcat gacggttacg gcaggtcgta atatgttatg ggatctgttt attcaatctt
    22501 atcagcaact ttatgcgaag tatggagaac aaaacgcagc gattatcaaa gaaaattgtc
    22561 agacacatat ttatattatg tcgacagatg ataataccat cgaagaattt tctaaaaaag
    22621 tggggaataa gacggttgaa caagagaaca gtaccatcaa ttcattaggt atgaatactc
    22681 atatcaatcg caatgttgat tcagatcgta tcttaactcc tgaaagaatt tctacttttt
    22741 tagaaggtga aacgattgta ctcgctcctt taaaacgaca agatttgaaa ggtcataaaa
    22801 tacggccgta tcctattttt aatcatgggg aaacgaatct tccttatgct tatcaatata
    22861 ttgaagattt caatccatcg tgggatatca atgatataga catacattgt acacatgcgg
    22921 acttggatct taaggcttta caaattgatt atgattattt cctaccagat gaatatgcta
    22981 gaaatctcta tcatggactg catgatcaat tagaagaaaa aaacgaagaa aatatgtttt
    23041 ataaaatcgt tcaatctttt gagaatgaga cggctaaaaa attgttaatt caattttacg
    23101 aagaacaagc aacggatcgt cttcaagaat atgttgaaaa gttgatcaaa aatgaagaaa
    23161 tttctgaaat gattaggaaa cggctgttat tggaagctga aaaggcggtg aaagaatgat
    23221 cattggagga attttctctg gcatagccga ctggtggtca ggtttattcg gagaagggga
    23281 tgcagatccc aaaaccgtaa cgaaagtctt acaagattat ggtaattatc tgcagtatca
    23341 agatgtattc agttggattt gtaatacttt tttatgggga ttgatcaaag ggttatataa
    23401 tctcaatact ttattagaaa aaacaattta tcaaagcttt gatttaaaag acttattgaa
    23461 cgccgctggt gttaatgaac tatttcaaag tttgattagt aaggtattgg ctcttttttg
    23521 tgtcgtcaca ttaatttatt taggcttgaa attttttatg agtaaacacc caccgaaagt
    23581 caaaaatatc ttggttaatt tatttatggc catgatcttg atttttggtg gtagttcttt
    23641 aatcgatgaa gggttaaata tcagtaaaaa cttttatgga gacgtcactg cagcaaataa
    23701 agcagataaa acgggttcac ctgcttttca aattattcaa aataatgtga ttgatgtcag
    23761 tacattacta gcgactgacc cgaataaagt agaatcctta ccaacagata aaagaaatgc
    23821 tttaacagcg aaaaatttca aaacagcgaa tatcaatggg attattacac ctgatcaagc
    23881 taagaaaatg tctgaatcaa gtgatattag tacagtacaa aaagatcggt taaaggcatt
    23941 acagtatcga ctagagttag acgataatgg gaaagaaatc cctgttcaaa ttagtgatga
    24001 aggtttagca aaatatgtgt atacgtcagg ctatcgtcga tacattagta gtccagggat
    24061 tattttggct ggggaatctt ctttgtcggt agcctattta tttattttgt ttacaatcgt
    24121 tacttgcatt attgagctag tatttaaaaa attctattta gtaattgccg cgtcaacgga
    24181 ctttgagaca ggacaacgga tgaaaagtgc gatagaagat atttctcaat ccttcttgtt
    24241 attggcgttt acgattttag aattacgaat ctatacatta atgctttcag gtatcggtga
    24301 tttgcatgcg gtaggaaaga tcaatggatt cttgtatgtt gttgctttaa ttgtgctaac
    24361 tattgcgcta ttcaaaggct ctcaatcggt tacgaagatt ttcggtgttg atacgagtct
    24421 gaaaaacggc agcaattctc ttcttagcat gtttgcctta ggaaatattg cgaaaaatgt
    24481 gggtagcgga gctaaaaacc ttgcaagtgc tggtaagagt ggtttaagcc atttaaatga
    24541 tattcgtaag aatggatttg gccatcgaaa agatattacc catgataacg gggaagaaca
    24601 atcagacgat aaagctacaa ctgtacctaa tagtaagaag acagtttccg aaatgttcgg
    24661 gaaagcgaaa aatggtgttt ctaaagccgc agaaggtctt ggttacgtca atgaacgtgg
    24721 gttaaaagga acagttgaag atcttacaga aaaagccaaa gacaccttag aagagaaatt
    24781 agacggcacg agagctaaag aatttgctga agctgtgaag aatccatccg aagcactaga
    24841 aaaacaaaaa gaaaaagctt cagcagtcaa agaaggacta aaagatgcgt atggtgaagg
    24901 acaagtcaat gcagcagtga aggcaaatac aacaagtgaa aaagaaaatc aagaaggtgc
    24961 agcgattcct tcagccaaag atcaccaaga tgagttacat tctaacgaaa attcgatcgg
    25021 agaaaaagat tcagaagaag gacaacatgg tcagttacca aaaaccgatc cagaacaata
    25081 tcgttataaa tctaacatta attctgaaaa cgaaaaacgc atttcagatt taccaaaacg
    25141 aaatcaagaa gtacaaacgg atgaggattc catcgatctg ccaaatgata atggcatcga
    25201 agttggaact gaaaaatcaa cgaaaattgg tttgcctaag acacaaaatt taccaatgaa
    25261 agatagtcgt ttgaatcaat tcaaagagaa tgatcaaagc tttgttcatc aatcacctgc
    25321 aggtactgtt caaatgaaat caagtcgttt gcctgaaaat ggaaatctga caactgtttc
    25381 ttacaattta gctgaaagtg gtgaaacaga gaatgcgtcc gttcaaaata ttgtgacaaa
    25441 agaagctgca cctaagccaa tcaataaagt tcataatgga tacagaccag caaacgtagc
    25501 atttactgca ccgacaaaaa taaatgtgac aagagaaact aaaaacagga acaatgaatt
    25561 gaaagaacaa ctattgaagg atatcaaacc ataaaaggcc tatttaaggg cctttttctt
    25621 tataaaacaa gtttaaaatg gaaaggagaa aattgtggag gatattttaa tagctacgtt
    25681 tataactgca ctgggagcat ttttaacgat atttgtggtg actattaaag gatttaaaga
    25741 tacggatagt ttacaaaaag atcatcagtc tattttagat ggtcaaaaaa cacataccga
    25801 aagcattatt gtacaccttt cagaaggatt cacttatttg aaagatgcta tgcccacatt
    25861 cacagtaaaa ttaacggaaa tatttcattc tgttgagcaa atatcgtcag aattgaaaga
    25921 gcaaagacaa caaaaagatc gtcaacttgg ctcacttaat tttaggcaag aaacgataca
    25981 agaatcattg gagaatgtaa atcgattaaa cgatgaaatg caacgagttc atttggaaaa
    26041 tgaagaatta cgcgcacaaa attatgattt aattcaaaag aaaagaaatc tggaacaaaa
    26101 aattgttgaa ttaaaagaag aaaatcgtca attgaattat caattacgac gaggaaaaaa
    26161 tcgttctcgt gatttaggaa atgaattaga gttgtaatat ttagaaaaac gctgtgagaa
    26221 atcacagtgt tttttatttc taaaaataca aaatataagg ggtatggtta tattatggat
    26281 aaatacattc atatgaaaaa tcctccaaga tttagtgggg aatggaagtt tttcgccttt
    26341 ttctttttag atctattaac gcttggtggc tgcttttttt gggcgaaaat agtcaataat
    26401 cttgtccact taccactctt ttttgcactc ttgaattatg gattatggct tgcgatagcg
    26461 ttagtgattg tttggcgacc ctataataac cctggtcaac gccaaatttt tgcgattatc
    26521 gaatctattt tctttacgga taagaaccac tatcatgcgt tagatcctaa ccgaaattat
    26581 catggtacgt ataaggagga tgaataaatg cgagtcaaag gacaaaattc agttgataag
    26641 aaatccattt tgcagtttgg aaaaccagaa gagcgctcta tcttggactt atttccatat
    26701 aaatcctgta cagaagaggg agtcttaatt actagagaag atcattttca gcgttattat
    26761 cgtgtcgttt ccactgacgt ggagggatta aatgaacaag agaaactaga acgaatgaat
    26821 cagttgacca ccgtcatgcg tacgtatgtg ccaacaatta agttagttag tttgaccaca
    26881 gagacggatc taacggaaca aatcgtgcaa aagcggcagt tattagataa aaatcgtatg
    26941 gaacagtcac taggaagaaa tctacagcga ttaagaaaat atgaaaagaa attagtagag
    27001 gagatccagg aattaaaacg ggcagaacaa gaacgtcctg acttaagctt ctttttcgtt
    27061 attgaaggaa agacaatcaa ggatttacaa actagaaatc gtcagttaat gcgatctagt
    27121 ggcattttag ggttaaaacc actctacaaa aaagaattga ttaagattct ttatcgaatg
    27181 aacaacatga atgacgaata aaaaagatgg aggaaatgat tcatgctaga tgtgataaaa
    27241 acagcttttt caacgcaaag taatcaaaag gtgattgatc cattaaaaca acttggtaat
    27301 cgtgaaatag agattttaaa atcaaaaggt tatgatttag atttcttaaa acaagtgatg
    27361 ccacaaggtg ggttgaattt tgatgaagaa tatgtgacct atggaaatgg ttattcacga
    27421 tgtgtgacag tttatcatta cacaaaaaat cctactcttt tttggttggc caatctcatg
    27481 aacaatcctc atacagtggc cacactagat gttagcacag atgaaaagca aaaagtgatt
    27541 gatcaaatca accgcgcatt agatgaatta aatgatcgat cagataatga acgaaaagcg
    27601 actgaccgaa ataaaagtgc ggaagaatac ctggaactag cggaatatgc ccgaaaattg
    27661 acttctaatg gggaaatttc taaacaagtc aaagtgagag tacatgttta cggaaatacg
    27721 atccaagaag tggatgaacg ggcgcaggaa ctgatcgaaa atctaaaagg gatggattat
    27781 cgtgcggtga cttatctgca taaaaccaaa cgagattggc aatcgatgtt taccatgttc
    27841 gatgaacaag ctgaatggtt tggaaatatc aaagggcaat cacttccatc gttaaacatt
    27901 ggcggaggat tcccgttcca ccaccaaacg ctaaaagatc caggaggcac acaatatggg
    27961 gaaaccatga caggcggccc atttgtctgg aatgccacgt ataaaaatag tgtacgttta
    28021 tctaccaata ccttgcttct aggaatgatg ggagctggta aatcgaccgt tcttaaaatg
    28081 atcgcggaag cccatttagc tgcaggagac tttatttggg gctttgaaaa gggaaaagac
    28141 tttattcctt tcttaaagga atataacggt attatggtgc gtttagacgg atctgacggg
    28201 atgatcaatc ctttagagat ctttgccaca cggacgtatg atgaagcatc cagtttatat
    28261 gacgatggtt cagtcaaaga tttgaagatc aatgaagcag cgtcctatca aacgcactta
    28321 gacaaagtag tctatcaggt acagttagtg agtcctcagc taaaaggaac gatgaaagca
    28381 gaattcaaga cctacttgaa tcgtttttat gaagagtatg gaacagtacc acgcggtttt
    28441 acttcctcaa attcgcgttc aaatactgat acgcaagtca cagggaaaga tccagaagct
    28501 tatccgacgt tcaaagaatt tttagccttt ttaggacaac tggaactacc aggggcttcc
    28561 caagagaaaa agaatcggaa agaagaaatg gagtctatcg tggaatcctt atgtgagact
    28621 tatggcatga tttttgatgg tcatagtacg attcgacacc ttgaccaaca acagttggtc
    28681 ttttttgaca ttgactctat tacaggccta gatcgagggg tacaacaatg tcagatgtac
    28741 atggccatga cgttgatttg gaatcaggca ttgattcaag gacgaagaca acgacgctta
    28801 attaaagaaa aacaaatgga agaacaagac ttcaaacgct tcttggcgat gattgatgag
    28861 tgccataatg cgattaatcc agatttcatt gaaacggtaa attatgtcac aaacttccaa
    28921 cgagaaatgc gtaaagtaga agcaatgact gttttagcta cacaatcccc acaagaaatg
    28981 gtgccagaaa atatgtcttc tgataacttc tcgaaactga agaaagtctt tgaattttct
    29041 tctacgaaga tctttatgcg tatggatgaa tctattttac gtcatataga aggattagtt
    29101 ggtaaatcaa tgacgaactc agaattagaa tccattcctc aacaaaatca aggagacgct
    29161 gtgatcaatt ttggctcaaa agaaaccatt cgtgttcatt ttagtccgaa caaacgtcaa
    29221 ttaaaattgt ttgatggagg aaaataatgg aaaaccaaaa tgaaagttta atcaaacagt
    29281 atgttaagcg tcgtgcaaag cggcgcttat ttttgtgggt gtttggtact tctgcaggtt
    29341 tgattactat attgatcact gtgtttgtga ccctttttct aatacttgcg gcaggttcta
    29401 ttgataattc tgattcaagt agtggtggcg aagcttttac aggagaatat tcggaaggct
    29461 tacccattta taaagaaatc aaaggaagag gccctttttc tgatgagatt gcgcaatatg
    29521 ctgtaggtgc agcagtgaag tataaattat taccaagtgt gatcctttcg caatacggtt
    29581 atgaatcagc gtttggtacg tcggcgtccg caagaaatga tctcaattat tttgggatta
    29641 cgtggtttga tgggtgtctg tttcctaaag gaactgcgcg tggaattggt ggcattgaag
    29701 gtggctggta catgaagttt cccaactcaa aagctgcctt ctcctattac ggctttatgg
    29761 tagccacaca atcaaatttt aatgcttgtg tcggaaataa aagccctggc gcaagcttat
    29821 tgatcttagg acgaggaggg tatgccgccg caggaattac tgaagacagt gcctattata
    29881 aaaattgtat gtctattatt aatacaaata aattgatgga gtacgatgag tttgcgatta
    29941 aacactggag agaaggcggc ggaactggtg gtacgattac aggaagctgg ggcaatccat
    30001 tcccaggaag tagcttagat aaaaattcgt tcagtggagg acaacttttt gggaaaaatc
    30061 caggaggaga attccgacct aacgggttcc atgatggact agactttggt tcagtcgatc
    30121 atccaggaag tgagattcat gcggttcatg gcggaaaagt cgtgtacgtt ggcaatcctg
    30181 gtatttcagg tttgggtgcg tgtgtgatcg tgattaatta cgatggcttg aatatggtgt
    30241 atcaagaatt tgcaaatagt acaggaaatt ctcgagtgaa agtaggcgat caagtgaaag
    30301 ttggtcaagt aattgggata cgagatacag cacacttgca tttaggattt actcgaatgg
    30361 attggcgtca agcacaagga catgcattca ttgatgatgg tacatggatc gatccgttac
    30421 catttttgaa tagcagcaaa aaatagatca ggagaaaaaa tatggaaaat aaaaccttaa
    30481 aaatcgtctt aacagctgca attagcgtta gtttaatcgg caatattgcg ttgttttggc
    30541 agcttaaaga agaacaagag acaaatacct ataaaattga agaagtggct aaaaacgcgt
    30601 ctgataagct caaaaaaaat tcttctgaag cacaggcgaa gattgacaag ttaaatcaaa
    30661 ccatcaatga gaaaaaccaa gaaatcgatc agctgaagca acaagatggc acaaaagcaa
    30721 aagaggaagt aactgaagca caaagaaaga cggcagaaga gttcggtcaa ttggccattg
    30781 ataaatcatt aagcagaaat gaattaacgg aaaaactaaa agatgtcgca acccaagaag
    30841 tgatcgacaa attaagtcct gtagacgatg atcaccaaca tgatgattac ggaagttact
    30901 cttttacatt aggtgacgtg caaacttacg ctcaaacaag cagtgtaaaa gaggaacaaa
    30961 attttgtcgt atttgttgat tatacaatcg gcaatcctca attcaaagat gtcaaaccac
    31021 aaaaaataaa aggtggatta actgtcactg aaaaacaagt agatggtcaa tggaaagtca
    31081 cagactttag ttatttcact cgttaggagg aagaaaatga gtaagaaaaa aggagcaaga
    31141 caacgtttta aaaaacgaaa aagttatctt agatggctgg ggatctttat gattctcggc
    31201 tttttgattc ttgctagtcc gatttacaca cataaaaagg tagacatacc agatgaagta
    31261 agcacgaacg catttttaaa cacgaaggaa ctgacgatgg tttcaaaaga aaaaggagcg
    31321 aaccagcaat tagtttttga atttgcgatc gacgatgaag atcagagctt attaaaagaa
    31381 ctagctaatc ttaattatcg tgtagaagta aagacagcta aaggggatta tcaagcaata
    31441 aaagccaaag tgatcaaggt gtctgatgat tattttgtag tgaagttagc acatgtacca
    31501 gaagaatata ttgctatgcg attaactatt attcctgaaa aaattgatcc aaaggtggat
    31561 atgcaagaac cgcaagatct gattttttat attcacgaag ataaggtcaa agatcacgtg
    31621 aaagacgaag attatgaaca acatgcgatc aattacaaag tgaaaggata caagaaagaa
    31681 caaaaagcag cacaaaaaca aattgaatcc ttccaagcaa ccattgattt gaatgaagaa
    31741 ttagtgaaga aactaaaaga tcaattgcct tatcaagtcg cagaagatca ggaaaatact
    31801 gaaaataaga ttaatagtta ccagcaagaa attgaaacat cgaaaacgca aatgaaagat
    31861 caagaagaga gcattcaaaa acttcaagaa aaaattgatc gtatgacaaa agaaaatatt
    31921 tagaagaata ggtggagtaa aagaaatgaa gcgagcgaac ttggtcggca aagatacttt
    31981 cgctgagcag aaagtattga ttaaagccta tctcaaagtt gtaaaagcta aagaaatatg
    32041 tcaagaagtg aattatctaa cacaacaata tctgagttga agaatggtag aaagagttta
    32101 gataccttaa aattcagatc atttgaagct ctatatatag ctgctaaaaa atattttaca
    32161 gctgataata aataaaaaat taaggtgggt tctatgtgaa aaaaacgtat caaaagtttt
    32221 tatggattag ctatatcgtc ctatttatcg ttgggtttct cgtcagtgtg tccgtgatcg
    32281 tcggaacgct ttttcttttg ttctctgacg aagatctggt acttaagggg ttaatgagta
    32341 cgttatcgtg tgtcatgtta ctttatttat gtatacagat caacgaaatt atgccccctc
    32401 attggcaaga aaagaagaaa gaatttaagg aagaaatcga aataaaatcc aatgactgga
    32461 ttgaatacac atggcttcct ctgaaaagaa atagcaaacg aaaggaattt tgggcattgc
    32521 aattatggcc aataggaaaa ctttttattt atatggcttc acttatggtt actttaatcg
    32581 gttatttggt ggtggtctat ggggtggcct attacttgtt aagtgagcca aaacagatcg
    32641 cggcgtcaaa tattttcacg gcagtaatga cattaatgtg tgtcatgtgc ttttctattt
    32701 ttagttactt actcgtccaa tttatcaggc aaaatttaac aatgagtaaa cttttcaaaa
    32761 gtttattgga cttacttatc ttaggcagta tgttaacgac tctaacagat cggttcgaac
    32821 aatctgaaaa aacggtagag gggataaaga acttcttaac gacgattgat caatttataa
    32881 atggatatat gtatttgttt gaagtaggct ttattctcac tttgtttggt tgtgtattta
    32941 taaaactcat taaaagatca atcgaaaaag aaatggttat tgatctaatt ccgacgctga
    33001 gcggctatga gtattacgtt gattttggaa agtatgagga gttgatccat acggatatcg
    33061 ttcacacgag tatccatgaa gtaaccgtta agggcatcag atctacttta aaagatggac
    33121 aggagacgaa aacaatcgac cgaagaaaag aggtctacaa tttttataaa gttgaagcaa
    33181 gtctacgata tggcattggg aaattgaggt tagatgggag taatattcaa caaaacaaac
    33241 catatgtttt aggaaaagtg gtgatttaga acttcctatg aaagatgaat aaataaggag
    33301 aatcttttga aaatgattct tctttacaga attgtgctta tagttggcac ggagttaaaa
    33361 atcttaaaga aggagcagtt attcaaagtg aaagaacatc ataatcagtt actatgtatt
    33421 aaaacgggta cgatgaacat tcaataccga acagaatatt tagaattaac gaatcaaact
    33481 gattttttgt cgattcgaga gcaacataag caagaaaaat taatggctac ttatagccaa
    33541 ttgattgatg agtgggaaca attcaaggaa tctaaaacat aaaattccat ttaaacacct
    33601 tattttttaa agagcataag gaaacgtgta cccactttca aaataaagtg ggtagatagg
    33661 ctgtgcctat cacgtttctg aaaaaaataa atgaccccaa aattttcaat ttatgtgtag
    33721 gtttatgggt agcaaaaata tgaatgtggg cagcaaaaag ttcatttgtg ggtagtaaaa
    33781 ttcaaatgtg tgtagcaatg tgtgtagcta cacacattgc tacacacgct ataacatata
    33841 gtgaaaagga gatatttatg gaagtaaaaa taagagatat tgatgaaaaa acgattcaaa
    33901 gaattgaccg aagatgtatt gaattaagtg aacgcaccgg gactaaatgg agccgaaatc
    33961 gatacctaaa agttttgatt gaaaatgatt ttgaccatga acttatggat catagaaaag
    34021 atcaatttga tcggttgtta gaaaaatttg tggatattca aacttataat acgaaaattt
    34081 tagaagaata tattgcaaca aataatcaat taatcgcctt gttaattgaa taataaaaat
    34141 agtattgtga atttataaaa ggaggaaatc aattttggca aaagcaacaa gaaaacatgt
    34201 atatctttac gatatgcata tcgaagtact tgatgaaata atttctactc atgaagatat
    34261 atctaattat agtgaagcag tcagacattt gtgtatgatg tatgatccaa aaatcgaaga
    34321 aaaaataaat ccaattcaaa ttaaattgaa tgcaatggga aaagaaattt ctatattaac
    34381 cgaaatggtt tcagagtttg cggatcttca tttgaaagat acaggaatac taattggtac
    34441 aaattcaact gtctatcaag aagcaaaaga gcgtgtggaa gggaaaataa aagcgaatca
    34501 aacgaaaaag tattctccta agatcaagaa accaataaat gaatctgttc atgccagagt
    34561 agacccgttt gatccaacaa agtttttaaa aagataaaaa gtagaagggg aacatgatga
    34621 ataaatcgcc tgcagtcatt ctcacttgtc aatttacctt gcccaataaa aaatcttttt
    34681 caacatacat tgattatatg acaagagaaa aagcgctgga agaaaaggaa cgacgcacgc
    34741 cggacgaaga acaggaactg caacgaatca agaatgcttt agaggatttt tatattcctg
    34801 aaggagaaac tttttcggag agtaagacag ataaagaatt cagtgaaacg tcgaatgaag
    34861 ctcaatcgtt gatggaacat ggaatcaatt ttgacaagtt agaggaacaa gattttacca
    34921 aatatctttc ttatatgacc cgtcactatg cgttagaaca aaagaaagaa ctgacgcaaa
    34981 gggaacaaaa agaataccaa cggttgaacc aagcaatgaa aaaatatcaa acagagccac
    35041 ataaaaaagc ttcaggaaat cttcctggag ttttttctat ggcttcagac gaagtgaaag
    35101 gaagtgatct gaaggagatc aaacaaatct tccaaagagg gcaacaaaaa ggctcaatca
    35161 tttatcaaga tgttgtctct cacgacaatt cgtatcttga aaaaatgggc ttgtacgatc
    35221 ccaaaacaga taccttagat gaagaaggat taaaagcagc tggaagaaaa atgatggaga
    35281 cattattcga gaaagaacaa ttgaatgaaa caggttactg gatggcaacg attcaccgta
    35341 acactaagca tatccatatt cattttgcag ttgttgaaaa agaaaatacg cgtaaacctt
    35401 acacggaggt tgaaaatggt gtgagttata tcgtaccgaa aggtaagaga agacaagcaa
    35461 cattagacgc aatgaagacc aattatgtac atgagttaga acgtttttct tatgaaaagg
    35521 atcgaatgat tggtatggag aaacgaaatt tattgacgcg gaaaagtgat ttgcgtaaca
    35581 ccttaacaaa agtggtaaaa gagccagcgc gttacgatcg acacgcaatg aacttattaa
    35641 atgaagtata taaaacccta cctgacaaac gttcggaatg gcattatggg gatgaaaaac
    35701 gaaccaaact ttcaccatac acaagagaga aactcgatga gttaaccaaa tatgtgttaa
    35761 caaaagaacc tgaatatcaa gaatatatac agatttcaaa atcattgaaa gaagaagcaa
    35821 aaagtcttta tggggaaagc aagagagaat caaaggatgc agaaaaaaat gctctctttg
    35881 atttgaagaa gcgcacagga aatgccattc taacagaact gaagaaacag gatagtcaaa
    35941 taaaaccttt aatagaaagt atggatcaga tgcaatctat ttacaatgaa cgatcctttc
    36001 gaacgcttaa acagttacca acgaatgaat acaaatatag ttacgaagaa ttcatgaagc
    36061 gcaggaaaca attccaacaa agagttgtca cgcaacggag tttgcgtcaa ttaaatcgaa
    36121 cgattaatgc ccatgaagaa aaataccacg caagtaaagc ctacgaagag caacaacgaa
    36181 gaattcaaat ggaacaagaa agacagtaaa gacagtagga ggaatagcaa tgaaacaata
    36241 tttagatcaa tggaaagtta tagaaggatc attaagagaa gaacgaatcg aacaacttcc
    36301 cgattgttta gaaaaagagc atttgtttca gataagagaa atgttgagaa acgaacagtt
    36361 tgatccaaat caatttttag tcgttgagta ctcagctact ggtgtgtact gttgtaatca
    36421 tgtgaagggt gaaaaatatt ttatcattca agaatatgag ggcaagttag cgccttatta
    36481 tactacttgg gaaatgaatg aagaggggat caataacttc ccgtgtaaaa gcattgaaga
    36541 gtctatttca ctcacagaat gttagttgtt aagtgaataa aagaagtaaa agagtcctga
    36601 acgtaattgt ccaggactct ttttttcaat gaattgtttt ccgccaattc aatgagtggt
    36661 gcgatttgcg actacattat atcaaaagaa agagaaggga ggaagaagaa atggcttatt
    36721 caacgattgg agttgttgtt gaaaaaagca gagacaatct cgtttttgtg acagaaattc
    36781 aaacgggcag agcttttgtc gtcacagaca aagcggcaaa agcgtatcaa agtggcgata
    36841 ttttaacgtt aaatctgact acgaagacgt tcgtcgatgc ggcagaagat tatccatt
//
LOCUS       DAFEIE010000025        36818 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFEIE010000025
VERSION     DAFEIE010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.025"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            316..2094
                     /gene="uvrC"
                     /locus_tag="LP345_001364"
     CDS             316..2094
                     /gene="uvrC"
                     /locus_tag="LP345_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBL1760151.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            2239..3138
                     /locus_tag="LP345_001365"
     CDS             2239..3138
                     /locus_tag="LP345_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760152.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            3131..4393
                     /locus_tag="LP345_001366"
     CDS             3131..4393
                     /locus_tag="LP345_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760153.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            4556..6454
                     /locus_tag="LP345_001367"
     CDS             4556..6454
                     /locus_tag="LP345_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBL1760154.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(6753..7472)
                     /locus_tag="LP345_001368"
     CDS             complement(6753..7472)
                     /locus_tag="LP345_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBL1760155.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            7809..8141
                     /locus_tag="LP345_001369"
     CDS             7809..8141
                     /locus_tag="LP345_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760156.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            8128..10131
                     /locus_tag="LP345_001370"
     CDS             8128..10131
                     /locus_tag="LP345_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBL1760157.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKHQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            10150..10620
                     /locus_tag="LP345_001371"
     CDS             10150..10620
                     /locus_tag="LP345_001371"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBL1760158.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            10641..11225
                     /locus_tag="LP345_001372"
     CDS             10641..11225
                     /locus_tag="LP345_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBL1760159.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            11240..12226
                     /locus_tag="LP345_001373"
     CDS             11240..12226
                     /locus_tag="LP345_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBL1760160.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            12216..12527
                     /locus_tag="LP345_001374"
     CDS             12216..12527
                     /locus_tag="LP345_001374"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBL1760161.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            12549..14330
                     /locus_tag="LP345_001375"
     CDS             12549..14330
                     /locus_tag="LP345_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBL1760162.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            14323..15699
                     /locus_tag="LP345_001376"
     CDS             14323..15699
                     /locus_tag="LP345_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBL1760163.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            15706..16341
                     /locus_tag="LP345_001377"
     CDS             15706..16341
                     /locus_tag="LP345_001377"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBL1760164.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            16371..17726
                     /locus_tag="LP345_001378"
     CDS             16371..17726
                     /locus_tag="LP345_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBL1760165.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(17918..19312)
                     /locus_tag="LP345_001379"
     CDS             complement(17918..19312)
                     /locus_tag="LP345_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL1760166.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFNSPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIYNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            19404..20375
                     /locus_tag="LP345_001380"
     CDS             19404..20375
                     /locus_tag="LP345_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBL1760167.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            20372..21154
                     /locus_tag="LP345_001381"
     CDS             20372..21154
                     /locus_tag="LP345_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBL1760168.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(21323..21694)
                     /locus_tag="LP345_001382"
     CDS             complement(21323..21694)
                     /locus_tag="LP345_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1760169.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            21828..22271
                     /locus_tag="LP345_001383"
     CDS             21828..22271
                     /locus_tag="LP345_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBL1760170.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(22314..23123)
                     /gene="yidA"
                     /locus_tag="LP345_001384"
     CDS             complement(22314..23123)
                     /gene="yidA"
                     /locus_tag="LP345_001384"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBL1760171.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(23142..24509)
                     /locus_tag="LP345_001385"
     CDS             complement(23142..24509)
                     /locus_tag="LP345_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1760172.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(24493..25323)
                     /locus_tag="LP345_001386"
     CDS             complement(24493..25323)
                     /locus_tag="LP345_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBL1760173.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            25486..25923
                     /locus_tag="LP345_001387"
     CDS             25486..25923
                     /locus_tag="LP345_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBL1760174.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            25999..26619
                     /locus_tag="LP345_001388"
     CDS             25999..26619
                     /locus_tag="LP345_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBL1760175.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            26808..27314
                     /locus_tag="LP345_001389"
     CDS             26808..27314
                     /locus_tag="LP345_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBL1760176.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            27331..28230
                     /locus_tag="LP345_001390"
     CDS             27331..28230
                     /locus_tag="LP345_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBL1760177.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            28317..29201
                     /locus_tag="LP345_001391"
     CDS             28317..29201
                     /locus_tag="LP345_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL1760178.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(29393..29464)
                     /locus_tag="LP345_001392"
     tRNA            complement(29393..29464)
                     /locus_tag="LP345_001392"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(29429..29431),aa:Arg,seq:ccg)
     gene            29524..30858
                     /gene="rpoN"
                     /locus_tag="LP345_001393"
     CDS             29524..30858
                     /gene="rpoN"
                     /locus_tag="LP345_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBL1760179.1"
                     /translation="MKFEQNFSQKQQQTQKLTMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            31007..32098
                     /locus_tag="LP345_001394"
     CDS             31007..32098
                     /locus_tag="LP345_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBL1760180.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            32139..33140
                     /gene="gap"
                     /locus_tag="LP345_001395"
     CDS             32139..33140
                     /gene="gap"
                     /locus_tag="LP345_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL1760181.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            33250..34440
                     /locus_tag="LP345_001396"
     CDS             33250..34440
                     /locus_tag="LP345_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBL1760182.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            34544..35299
                     /locus_tag="LP345_001397"
     CDS             34544..35299
                     /locus_tag="LP345_001397"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBL1760183.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            35415..36713
                     /gene="eno"
                     /locus_tag="LP345_001398"
     CDS             35415..36713
                     /gene="eno"
                     /locus_tag="LP345_001398"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBL1760184.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        12197 a         6450 c         7832 g        10339 t
ORIGIN      
        1 tatccattga gagactcctt tggtaggatg acgttttggt cgactaaatt ttaccaaaag
       61 tgagtctctt tttgagttga aacgaagaaa aagtgttagt agaaaatcgc cttcgatttt
      121 ccaccaacac aaaatattat agaaccaaaa taagctgagg gtgggactga atccagttcc
      181 gtcctcggtt tttttgcggt tgagttaagg ttattcaaat taatattttt tgagtataat
      241 tacgttgtca ggctggattg tttttttgac agacatgcta taataacttt aattgaatat
      301 gaaggggagt accagatgaa cgaacgaatc aaaaacaaat tagctttact tcctgatcag
      361 cccggctgtt acttgatgaa agataaaaat ggaacgatca tttatgtcgg caaagccaaa
      421 atattaaaaa atcgtgtccg ctcatatttt actggcagcc ataatacgaa aacggaacgg
      481 cttgttagtg aaatcgaaga ctttgaatac atcgttacag aatcgaatat cgaagcattg
      541 ctcttagaga tcaatctgat aaagaaaaat gatcctaaat acaacattat gttaaaggat
      601 gataaaacct atcctttcct taagataacg aatgaaaaat atccccgttt ggtgattact
      661 cgtaaagtac taaaagacaa agcactgtat tttggaccat atcccgatgt cggtgcggcg
      721 aatgagacaa agaagatcct cgatcgatta tttcctctga gaaaatgcaa acctagtcag
      781 acgaaggagc cttgtcttta ctatcatttg ggacaatgtc tgtgtcctta ttatttcgac
      841 gtagatccga aagtctatac gaaaatcgtt gatgaagtga aaaagttttt aaacggagga
      901 cacgaaaaaa tcgagtcaga gatccatcag aaaatggaaa aagctgctga aaacatggag
      961 tttgaaaaag ctgcagaata ccgagaccag atccgtgcca ttgagacaat catgactcgc
     1021 caaaaaatga caaatactga tttactggat cgagatgtat ttggttatgc gattgacaaa
     1081 ggatggatgt gtgtccaagt gtttttcgta agacaaggaa agctaattga acgagatgtt
     1141 tcaatgtttc ctttctataa cgaagcagaa gaagatttct tgacttacct cggtcagttt
     1201 tatcaggaaa atgagcattt cattcctaaa gaagtcttga ttcctgatac gatcgacaag
     1261 cccagtgtag aagctttgtt agctacgaaa gtgctgcaac caaaacgagg agaaaagaaa
     1321 aaattagttg aattggcgaa taagaatgcc tcagttgctt tgaatgaacg gtttgatctg
     1381 attgccagaa aacaggaacg gacgatcgga gcagttgaac gtttaggaaa cgcgatgaat
     1441 atcccgaccc caatacgtat cgagtctttt gataactcta atatcatggg gacgaatcct
     1501 gtggctgcga tggtcgtatt cattgatgga aaaccggcaa gaaaagaata tcggaaatat
     1561 aaaataaaaa cagtcaacgg accggatgat tatgcatcaa tgagagaagt catctatcgc
     1621 agatattcac gagtgattcg cgaagggttg cctttacctg atttgatctt gatcgatgga
     1681 ggaaaaggac aagtagatgt ggcaaaagat gtcttagaaa atcaattagg aatcgatatt
     1741 cctattgctg gcatggcaaa aaacgataaa cataaaacaa atgagttgct attcggtata
     1801 gatttggctg tagtaccgct tgagcgaaat tcaccagagt ttttcttact ccagcgaatc
     1861 caagatgaag tccatcgatt cgcaatcact ttccatcggc agctacgcag taaaaacagt
     1921 tttgcttccc gattagatga aattgaaggg ttaggaccaa aacgaaaaaa aatgctgctt
     1981 aaagagttca aatcgttgaa aaatatcaca gcagccacga cagaagaatt acaagaaatc
     2041 ggactgccga aaaatgtcgc acaaaacgta tttgataaat tacatcagga atgaggaaag
     2101 ggcactttac aaagaaagta aagtgtccta tcattttatg tacaacaaaa agagcgttta
     2161 cgttttgttg gtaaataata aatcgcttac gtctggtgtc taaggatata tgtgatttct
     2221 tgaagaagga gtgaagaaat gttagaagtc aaggatcttg ttaaaacttt tgggaactac
     2281 acagctgtcg atcatgtctc tttccaaatc cccgatggaa aaatcatggg gctaattggc
     2341 caaaacgggg ctgggaagac aacgactttt cgtttgatct tggatttttt gacacaagac
     2401 caaggagaag tgttatggaa tggccatcat cttggggaga aagattatga tgtcatcggt
     2461 tatcttccgg aggaacgggg actttatccg aaagtaacga ttcaagacca actgctttat
     2521 tttgcagaac ttagagggaa atcaagaaaa gagattgaac caaaaatcga tttttggatg
     2581 gaaaaatttc aggtaaaagg gaaaaagacg gataaagtaa aatctttgtc taaaggaaat
     2641 cagcaaaaag tccagctgat cgccacgtta atccatgaac ctaaattgat cattttggat
     2701 gagccattca gcgggttaga tccggtaaat gctgaattgc taaaagatgg aatattggaa
     2761 ttgaaaaaac atggttcatg tgtcattttt tctagccaca atatggataa tgtagaaaaa
     2821 atctgcgatc atttgatcat gttgcgaaac ggaaaaatgg ttttgaatgg aaaagtacat
     2881 gagattcgtg aatcatttgg ccgtacgaag ttattcttgg aatctggttt aagccaacag
     2941 gaagtagaag aaatcgaagg cgtgaaaaaa gtgatccttc atgaagacaa tacgttagag
     3001 attaccttag aagatcctga agctgggaaa gaaatcttta ctcgtgcgac tcagttcggc
     3061 tacattccta tgtttaacca gcaaccgcca actttggaag agattttcaa attgaaagca
     3121 ggtgaaatcg atgcgtaagt tttggattat taccaaagat gtctatttaa aaaatgttaa
     3181 gtcgatttct ttcttgatca tgatattagt cccttttatc atgctgggta tcatttatgt
     3241 agcaggaaac tttgctcaac aaaatagtga tgtcaataaa atcggcgtat tggctgataa
     3301 tgagcaaatc agtcagcaaa tgagccaagt caaaacagat gattttgagt tcaaagcagt
     3361 tgattctgaa gaaaaagcac aaaaagagct ttcggaagaa aaaatcgatg cgtatttagt
     3421 agtctcaact gagaatgata agataaatgg gatgctttat agcgaaaatt cattaggaca
     3481 aagtacacaa ctactgatac aacaacaact gactggcttg caatcgatgc ttcgagcaag
     3541 tcaattaggc atttcaccag aagaagtagc tagcttgagc caacaagcaa gtttgactcg
     3601 acaaaaagtc aattttgatt caaaaggaaa aatgacagtt ggagaagata actcgacagt
     3661 ccaatatgtc gtaagttatg tagcaacgat tgtcttgttc attattattt tgacgtatgc
     3721 gcagatcatt gcacaagaga tcgcttctga aaaaggcacg cggatcatgg aagtgatcct
     3781 gtccagtacg actgcacaaa agcattttta cggaaaacta acaggtgttt tacttgttgc
     3841 attaacgcaa atggcattat acggtattat ttttggtata ggatacagtc aattcaaaga
     3901 tatggaaatg gtcaaaaata tattagacgg tatctcattg gataacttga ttggaccatt
     3961 cttgtggtat tctcttctat tcatgatctt tggcattttg attttttctg ttttagcagc
     4021 tttatgtggc tctttggtca acaaagcaga agatacagca aaagcaattt tgccagtgac
     4081 ttatctatct ctaggcggat atatgcttgg attgatacta ggagcttcag atccaaacaa
     4141 tatcgttatt cggatcactt cgtatattcc attcttatct tcatatatta tgccggttcg
     4201 cttagcaaat gagacagtcg gtatgggtgg agcattgatt tccttgttgg tacttgtagc
     4261 cgtaacattc ttattgatga tcttgtctgc aaacatgtac aaatcgaatg tactcgtgta
     4321 tagcgaaggc ggattatgga gttcattgaa acaatcgatt tcaattatga gaaatgaacg
     4381 aaaaaaagca taaaatatag aaaaatatag aaggaagctg gacatttatt gttcccagct
     4441 tcttttttgt atagacctat ttctattttt ttattatatt ggatatatat attcattgaa
     4501 aatagagcat aacaacttta taatgttgag tataccaatt tttggaggcg ttttaatgga
     4561 ccgctattta gatttacttt cagagaagtt ccctacaacg gaagatgtca tcacggaaat
     4621 catcaatctc gaagcaattt tgcagcttcc aaaaggaaca gagttatttt tgagcgatat
     4681 acatggcgaa tttcctgctt ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga
     4741 aaagatcaaa gaccttttct ctgaacaaat gacggaaacg gagatcagcc aattcactat
     4801 ttttacggct tatccagaat atgtgttgac gactgattgg tacaaaaaac aagataaatc
     4861 ccagctgatc catcgtttga tcgatctttt acggtttacg acagtcaaat acactcgatc
     4921 aaaagttcga aaaggattgc cgaaagaata tagctatatc attgaggaac tcttgtatat
     4981 cgatgatcgt atcaacggga aaaaagacta tgtaaaaaaa atcattgaac aacttgtctt
     5041 gatgaaggaa gaagaaaaat ttttaacaaa acttgcgcag acgatccaaa aatctgtcat
     5101 cgatcatttg catatcgtgg gtgatatttt tgatcgagga actcaagcag ccaaagtaat
     5161 ggatcgaatc atggattttt cctctgtaga tatccagtgg gggaatcatg atattttgtg
     5221 gattggtgcg tattgcggct ctgaggcatg tttattgacg cttttacgga ttgccgcacg
     5281 ctacaactat ttatttgaat tagagaaaga atatggatta aatttacgtc cattattttc
     5341 ttttgcccat caaacctatc agaagaatcc agtatttacc cctaaaaaca ggaaagatct
     5401 atctgaaaga gagcaagaag aattagaaaa gatccatcaa gcactttcta tcctccaatt
     5461 caaatcagaa catcagttgt tgaatcgacg acctgaattt aaaatggacg atcgtaaatt
     5521 gttggaaaaa atcaactatg aggaatcaac gatcgtttta gaaggtcagc tctatgagtt
     5581 gaaagggact tgttttcaaa cgatccagcc agatgatcct aaaaaattct tggaagagga
     5641 acaaaaagtg atcgatagtt tgatgtattc attccagcac tcgttaagaa tgcaaaaaca
     5701 catgacgttt ttgatcgaaa aagggggaat gtatctcacg aacaatcagc atgtactgtt
     5761 ccatggctgt atacctgtag atgaaaaggg gcagctctta gcatttgaat tagaccaatc
     5821 ttatcgcgga aaagaactgc tgggattttt tgaaaaacag ataactgaaa gcgcaaaaga
     5881 tttgactgca aatgaagatt tggcgaccga tttgatttgg tatgcgtgga gcgggccatt
     5941 ttcgccttta ttcggcaaga gtaaaatggc aacttttgag cgctattttc tcacagagcc
     6001 tcatacgcac gtcgaaaaaa gcaatcccta ttatcacttg cgagatgaag agtggttcag
     6061 tgaaaaaatt ttggcagaat tcgatgcaaa agaagaaggt tcagcaatca tcaatggaca
     6121 cacgccagta aaagtaaaaa aaggagagtc accgatcaaa gcaaacggaa aagcatttgt
     6181 tattgacgga ggtctatcca aagcttatca aaaaacaacc gggattgctg gctactcatt
     6241 actatgcaat tcttacggtt tccaaatcgt gacacattat ccgttcttgc ctattgaaca
     6301 acaatttgca aaaaaatctg atcaaacgaa tgtaaaaaaa gtgatcgagc agcagctccc
     6361 acgcaaactt aatcggaata cgacaaaagg aatggaatta cagcaacaga ttactcaact
     6421 ccaaaggctg ttggattatc gaaaggacga ttgagaaaaa tgctagccaa cattgctcaa
     6481 tagactaaaa agcgactgca acaaaaggcg tgtcgcagtc tccttcggaa ttagctcaaa
     6541 aaacggtaaa atattagaag ctatttttct gtttatttct ctaatactca ggtcagggcg
     6601 ctgatttcac gacctcttcc ttaaacggtg ttctcctgcc aactcctcgg tcacaagtca
     6661 caatatccaa caaacatgag aagctgtttt ttgaaattgc tccttgtgac tcagagttga
     6721 acggcaggct cacgacctaa tcagaaaaac gattaaaatt cattcacaaa gaaatcgaat
     6781 aaacgctgtt cagatgaatc tacacgatga gaaagttccg gatgccattg gacaccaagg
     6841 attttgtgca tattatcttt actttggact gcttcaatga gtccatcgtt ggaaaaggcg
     6901 atggctttta acaaaggaga aagatctttg actgcctgat gatgatagga attcacaaag
     6961 tatgaatcag ggagaaggtc acttaataaa ctgtccgaaa cgattttgac ttcgtgagtt
     7021 gcaaactgcg gggcagtggg ctgttgttcg tgttttacgg accattttgg atataatgaa
     7081 agatcttgat aaagtgttcc ctccaacacg acattcaata gttgaagtcc tcggcagact
     7141 gcaaaaatcg gttttctttg tttcaatgct tccaagatca atgcctgttc gaattggtct
     7201 cgttgaatat ttgtttccgt cagttttgga tgagggtctt ccatgtaaag ttgcggacta
     7261 acatcctgac cgcctgcaag aatgagtttg tcgattttct caattagttg aggcgctgaa
     7321 tctggagaca tgactggcag aataagaggt aatccttgag catctaaaac tgcatccaca
     7381 aatccctgcg gtgtatagct tacttgattt ccttggaaag tatctgtcgc tcgaatcagt
     7441 tgattcccgg caatgccgat gattggtttc atttttattc cccctaaagt agactaattg
     7501 taacaaggat ttaaaaaaat ttaaactatg taagacttgc ccctatactt atctgttctt
     7561 gctgtgttac tatctgtaaa gagaattttc gtgtgaaatt catgacgata gttgaaaata
     7621 ttgcttaatt tgttataata aaaagtaagc agaaataaaa aggttgggcg taagcttcaa
     7681 ggatctagtt cttcaagggg tgagaaggac attttattga aggggcctgc ctatactaag
     7741 ttatctttag aggtacatac tttcaatgaa aaaagaaagc atgtacctct tttttaaatc
     7801 gaaaggaagt gaagcaagtg ttagaagctt tggaacaaat ccgaaaagca gaagaagaaa
     7861 atgagaagcg tgctcgaacc ctacggcagc agttgaagac ctatgcagaa gaaaaagagc
     7921 aagaattgga gataatccaa acgaacagtc ggcaacagct gaaacagttg gtagaagaaa
     7981 aagaacaatt cgaaaagcaa gaattagaaa aagaaaaaat gaaattgaaa gcagaagcag
     8041 acaaggtgca agcaactttg aaagaccaat atcaaaagca tcagagtcaa gcaatcggtg
     8101 caatcattga aagggtgaaa gaaacttatg gccgtcacta agatggaaaa agtgaccctc
     8161 atttcagata aaagaaatca ggagaggatt ttacaagcag tacaaggaat ccaaaatgtt
     8221 gaaatccggg atctgtatca aaatagaaca aacaaccagt gggtagaaaa atattttcca
     8281 gataccacga ttattgataa agaagcaaaa ttaagcgctt taggcaatcg gctgaaagac
     8341 atccaagaag ctatccaatt catacaacac cacggcgata gccgtcaaaa gaaactccat
     8401 ttgaaacatc aagaactttc cttacaagac ttggaagcaa attattccga agaaaatttc
     8461 atgaataaat tagaagaagt ccttgattta aaagaaaagt gggaacagct aactgaaaaa
     8521 cgtgatcgtt tagaagaaga ggaagaatgg cttcttcatt ggcaacagct ggatattgct
     8581 ccaagtatgt atgcaagtaa gacgaccatt tttgagatgg ggactgtgag tgcagcaaat
     8641 tttgaaagtt tcaaggaaga actaagtaag cttgatgacg tttatatgga agaaatagat
     8701 tatacgccaa aacaagttta tctttcgtat gttgctttaa aaaaatcagt tgctgctata
     8761 gaagaaattg ctgggaaata cgggttcaat aaagaaacgt atccttatga acaaaatcct
     8821 aaagaaaaat tgcaagaaac caaacagcaa ttatccattg ttcacgagca gcaaaaaaag
     8881 ataacgacag cgttaggtca gtgcagcggc tatatccaag aatttgaatg ggtagaagaa
     8941 gtcacacttg ccgttgcaga acgggaaaaa gtaaaagaac ggtttatcca tgccacttat
     9001 ctgatcgttt tgcaaggttg ggtagatgca gaagaaaaac agaatttgat gcatgtgtta
     9061 aacgaaactg tatcagaaga agatatatac gttagtttcg aaacaccaaa ctcagaagag
     9121 attcagcagg aagtccctac taaattgaaa aaccatccgc ttatcgaacc ttttgaattg
     9181 ctgactgaaa tgtacagtct gccaaaatat gaagaagtag atccaacgcc ttggatgaca
     9241 ccattttatc ttgtcttctt cgggatgatg gtcgcagatg ttggttacgg attgctgatg
     9301 ctcattggga caatactagc tcaaaaacta tttgttttac cccgcgggat gaaacgtttc
     9361 gtaaaattct ttgagattct ctcggtacca tcgatcatct ggggattgat ctacagttca
     9421 tttttcggac aggcattacc aaaagaacta tttggtatcc gcttgccttt cccaatccta
     9481 tctacgacgg atgacgtcaa tacgattttg attttatccg tgattttcgg tctgatacag
     9541 atcttggttg gattattcgt ggcagcaaag gaaaatatca ggaggaaaga ttacttgagt
     9601 gctgtcagtg atggttttgc ctggcaaggg atcctgattg ggatcgttat tgcattgatt
     9661 ggtgtcatgt tgataaaaaa tacagcattt gtttatcttg gcgcggggct atcgatcatt
     9721 gctgctttat gtatcttaat cgtgccgatt atccaatcgc cgtctaaagt caagggtgct
     9781 gccaaaggag cgtataatct ttacggattg actggttata tcggtgattt agtcagttat
     9841 acacgtttga tggcactagg tatttcaggc ggaagtattg gcgcggcatt caatatgcta
     9901 gttgctttca tgccgccagc cgctcgattc agtgtaggga tccttttgat catcgcttta
     9961 cacgcactga atatgttttt gacactgtta agtgcctatg tccatggtgc acgattgcag
    10021 tatgtcgaat tttttggaaa attttataca ggaggcggac gtgcctttga cccgctgaaa
    10081 acggcggaaa aatacgtcaa catcaatcat aagaaaaaaa acaataaata attggaggat
    10141 ttttatacaa tgatggatta cttaattagt caaaatggtg gaatggtatt tgcagtatta
    10201 gcgatggcaa cagcgacgat tttttcaggg attggttcag ctaaaggtgt tggaatgaca
    10261 ggtgaggcag cagcagcgtt aacaacaagt caacccgaaa aattcggaca ggctttgatt
    10321 ctgcaattgc ttccaggtac gcaagggttg tatggattcg ttatcgcctt tttgattttt
    10381 atcaacttag gaaatgatat gtcagttgta caaggattga actttctagg cgcttctctg
    10441 ccgattgctt ttacaggttt gttttcaggt atcgcccaag ggaaagttgc agcagcaggt
    10501 atccaaattt tagcgaaaaa acctgaacat gctacaaaag gaatcatttt tgctgcgatg
    10561 gttgaaacat atgcgatttt aggtttcgtt atttccttcc tattagtatt gaatgcctaa
    10621 gcataaagga ggaaaagcag atgaacgcca ttgaaaaaat catctctcag atgaatgaag
    10681 cagcagagca agaaagagcg gcgttagagc aagaagagcg aatgaagatc gatcaaaact
    10741 ttgaacaaaa acgtacgcaa atcgaaacag aacatcaaaa acaaaaagaa aaacaaatcg
    10801 aattacttga aaaaaaatac cgtcagctta ggaatcgcca acaagtagaa gtacgacaag
    10861 aaaatttgaa tgcgaagcag gaatttttac gacgattgtt tgcagatgca atagctgaaa
    10921 tggagaattg ggatgaatct gaacaaatcc agtttatcaa aaattcattg tattcattac
    10981 ctttgacagg caaagtaaca ttcattgctg gagaaaaatc agcagcttat ctttctcaga
    11041 cattgctgga tgaatggaac aatgaacttc cctttatgat ggttttaagt gatgaaactg
    11101 ttgctgatca agcgggtttt ctgataaacg atcaaggagt tcagtataat tttcttttca
    11161 gcagccttgt acaagatatc caaggaacga tgagttttga gattgccaat caattattcg
    11221 aataaggagg gatcagtgta tggaatacca cgaactaaat cccttgattc gcggaagaga
    11281 gcttgaactt ttgtccaatg agacatttga acggatgatt caaacaaatt ctgtcgaagc
    11341 acttggtgaa atattgaaat ccacgattta cagtccatat atttatgacg gatatgaata
    11401 tgacttcgaa cagaatcttt taaaggagca gagccgtcta tttcgctggt taaaggaatc
    11461 agcaccggag cctgaaatcg tttggatcta tacgatgcgc tatactttcc ataatctgaa
    11521 ggttttgaca aaagccgaga tgacaaatca aaatctggac catttgtata tcgacgatgg
    11581 attttattca ttagaaacct tgaaggatgc cattcatacg caagtttcaa atgaactccc
    11641 tgaaagcatt atggacagta tacgagaagt acgtgattat tttgaagagt ctaccattct
    11701 tcagggaatt gacgtgattt atgatcgaca gtttttgaca gagcagcgac ggcttgccga
    11761 taagctagga tatcaagaat tgctgacaga agtcattgct tttattgact tgaccaatat
    11821 cacaacgatg gctcgaggaa tattgcagaa aagaacatat gggttcatga cgacggtact
    11881 ttccagctcg ggaagtatcg aaaaagaagt atttttgaac tttgtagata aagatatgga
    11941 agattacacg aattttctat tagagacaga ttatgctgat tttctgcgcc ctgtcatccg
    12001 tgagggaaat cttgatctcg taaagcttga acagttgaaa gatgattatc taagttcatt
    12061 gtatcaagaa gcacaaaccc aggctttcgg accactgcca ctactagcct ttttgaacgc
    12121 aaaagaggta gaaagcaaaa accttcgttt actggttatc ggcaaaagaa gccatttcga
    12181 accagaaaca atcagaaagc gggtgagaca agtctatgac gcataagatc ggtgtagttg
    12241 gcgacaaaga ttctgttttg ccattcaaat tgtttggctt tgatgttcgt tatggtacaa
    12301 ccaagcaaac cgttcgtcag gcaattgaag aaatggcaaa gaatgagtat ggcgtgattt
    12361 atgtcacaga gcaatgtgca gcattgagcc cagaaacgat cgaacgttac aaggaacaaa
    12421 tgatacctgc tatcgtattg attcccaatc atcaaggatc attagggata gggctggaag
    12481 aaattcaaaa aaacgtagaa aaagcagtag gtcaaaatat cttatagtat gaaaaggaga
    12541 tagaaatttt gcaaattgga aaaatcataa aagtctccgg acctcttgta atggctgaga
    12601 acatgtctga tgccagtatc caagacatgt gtctagtggg agatctagga gttatcggag
    12661 aaattatcga gatgcgtggc gatgtggcgt ctattcaagt atatgaagag acttctggaa
    12721 ttggtccagg cgaaccggtt cgctctactg gtgaagcttt atctgttgaa ttaggaccag
    12781 ggatcatttc acaaatgttt gacggaatcc aacggccatt agataccttt atggaaatca
    12841 cacaaagtaa tttcttaggg cgcggagttc aattgcccgc attggaccat gagaaaaaat
    12901 ggtggttcga accaacagta gaagccggag aaacggtgag tgctggagat gttatcggga
    12961 tcgtagaaga aacaaaagtt ataaaacata aaatcatggt gccaaatggg ataaaaggaa
    13021 cgatcaaaac aatcgaaaaa ggttcattca ctattgatga aacagtatgt gtcattgaaa
    13081 ccgaaaatgg tgacaaaaat ttgacgatgc ttcaaaaatg gccagtaaga cgtagtcggc
    13141 caatcaaaga aaaattaaac ccggatgcac ccatgatcac tggacagcga gtgattgata
    13201 cattcttccc agtgacaaaa ggaggagcag cagctgtacc tggtcctttt ggtgcaggga
    13261 aaacagtcgt tcagcatcaa attgcaaaat gggccgatgt ggacatggtt gtctatgtgg
    13321 gatgtggcga gcgtggaaat gagatgacgg atgttttaaa tgaattccct gaattgattg
    13381 accctaatac aggagaatcg ttgatggaac gtacggtatt gattgctaat acatcaaaca
    13441 tgccagtggc agctcgagaa gcttctatct atacgggaat cacaattgcg gaatatttcc
    13501 gtgacatggg ttatgacgtt gctatcatgg cagactccac ttcacgatgg gcagaagcac
    13561 ttcgtgagat gagcggacgt ttggaagaaa tgcctggtga tgaaggttat ccagcttatc
    13621 ttggttcacg gcttgcggaa tactatgaac gatctggaag agtcattgca ttaggatcag
    13681 aaggtcgcga aggaagtata accgcaatca gtgctgtatc cccgtctgga ggggatattt
    13741 cggaaccagt cacacaaaat acattgcggg tcgtaaaagt attctggggt cttgattcca
    13801 gtttagccca aaaaagacat tttccttcga tcgattggat acaaagctat tctctttatt
    13861 caacagaagt agggaagtat atggatcata tccttcaagc tgactgggca tccatggtca
    13921 ccgagggcat gcgtattttg caggaagaac agcagctgaa tgaaatcgtg cgtttggtag
    13981 ggattgattc cctttcagat aatgaccgtc tgacattaga agtggcaaaa tccattcgtg
    14041 aagattattt gcagcaaaat gcttttgatg atgtcgatac attcacttca agagagaaac
    14101 aattcaaaat gttgaagatg atcttgacct ttggtgaaga aggacgccgt gcgttgtcgt
    14161 taggtgctta tttaagtgag atcatggacg gtaccgtatc gattcgtgaa aggatcggac
    14221 gaagcaaata tatcccggaa acagaattag aaaaactaga tcaaattatt ggtgaaatca
    14281 agcaaacgat gcaaacgatc gtttcagaag gaggcatgag caatgattaa agaatatcgt
    14341 acgatcggtg aagtcgtcgg tccattgatg gcggttgaaa aagttgctgg tgtcaaatat
    14401 gaagaattaa tcgaagtccg tatgcaaaat ggcgagattc gtcgtggaca agtattggaa
    14461 gtccaagaag ataaagcaat ggtccaaata ttcgaaggaa caagtggtat caatttacgt
    14521 gactcttctg tacgattttt aggccatcct ttagaactag gtgtatcgga agacatgatc
    14581 ggtcgagtat tcgatggttt gggacgaccg aaagataacg gaccagagat cctgcctgaa
    14641 aagcatttgg atattaacgg agaagtaatc aatccagtag ctcgggatta tccagatgag
    14701 tttatccaaa caggtatctc tgcaatcgat catttgaata cattagttcg tgggcaaaaa
    14761 ttaccagtat tttctggctc tggtcttcct cataaagaat tagctgctca gatcgcgcga
    14821 caagcaacgg tactcgattc atcagatgat ttcgccgtag tctttgctgc tattggaatc
    14881 acttttgaag aagctgaatt tttcatggaa gattttcgtc aaacgggcgc aatcgaccgt
    14941 tctgtcatgt ttatgaattt agcaaacgac cctgcaatcg aacgtatcgc tactcctcgt
    15001 atggctttga ctgctgcaga atatcttgct tatgaaaagg gaatgcatgt tttggttatc
    15061 atgacagaca tgaccaacta tgcagaggca ttgcgagaga tttctgcagc acggcgagaa
    15121 gttccaggaa gaagaggata tcctgggtat ctttacacga acttagctac tttattcgaa
    15181 cgagcaggaa gaatccgcgg actaaaagga tcggttactc aaattccgat tctaacaatg
    15241 ccagaagacg ataaaactca tccaatccct gacttgactg gttatattac agaaggacag
    15301 atcatcttga ctagagagct ttacaagagt gggattcagc caccaattga tgtactcccg
    15361 tctctttcgc ggttaaaaga taagggaact ggacccggaa agacaagaga agaccatgca
    15421 gctacgatga atcagctttt tgcagcctat gcacaaggaa aacaggcaaa agaattagcc
    15481 gtagttttag gtgaatctgc tttatctgat gtagacaaga tctatgcgaa gtttgctgag
    15541 cggtttgaaa aagaatatgt caatcaagga ttctacacga accgttcgat tactgaaaca
    15601 cttgatctag ggtgggaact gctatcgatg ttgccaagaa ccgaattaaa acgaatcaaa
    15661 gacgacatgc tggacaaata tctgccagaa gggaagtgag ttctgatggc acgattgaat
    15721 gtgaatccga cccgcatgga attgactcga ttgaaaaaac agttgacaac tgccacaaga
    15781 gggcataaat tattaaaaga taagcaagat gaactgatgc gtcaattcat cctgttgatt
    15841 cgaaagaaca accagctgcg tcaagaaatg gaagagtcta tgacagaagc aatgtctgat
    15901 tttgtattgg caaatgcttc gatcacggaa cctttcatcg aagaattatt tgttttgccg
    15961 gcggaaaacg ttgatttgtc tatcgtagac aaaaatatca tgagtgtaaa agtacctgtg
    16021 atgaattttg aatatgatga acagctgaca gacacacctt tggaatacgg gtatttgaat
    16081 tccagtgccg aactggatcg gtcaatcgat cggtttacta ccctgcttcc aaaacttttg
    16141 gaactgacag aaatcgaaaa aacttgtcaa ctgatggcga gtgaaatcga aaagacacgt
    16201 cggcgagtca atgcattaga atatatgacg atccctcaat tagaagaaac gatctattat
    16261 attcgtatga agctggaaga aaacgagcgc gcagaagtaa caaggttgat caaagtaaaa
    16321 aatatgggta ccactgacta agtggtatct ttttttaaaa gaggaaaacg atgattaaac
    16381 aaagcaaaca aataaagaaa cgtttgccgg ctgttcagct tctcgcatta ggattttttc
    16441 tcctgatttt agttggcggc ggcctactta ccctaccatt ttttagtaat agtgggcatg
    16501 ggacaaattt tatcgatgcg cttttcactg caacttctgc tgtctgtgta acgggattga
    16561 caacattgaa tacagcagag cattggaaca gtgctggtca atttttgatc atgcttttga
    16621 ttgagatcgg cggtcttggt tttatgatgg ttccgattct atgctttgca ttgataaaga
    16681 agaaagtcag tctcagcaca cgtattatat taaaagaagc gctgaatcta gaagaagtat
    16741 caggtgtgat gaagctcatg ctttacatcc taaaattggc ctttgttatc caattgattg
    16801 gtacggttgc tttatctttt gtatttgtgc ctgaatttgg ctggttgaaa ggtatctggt
    16861 acagtttgtt ccatgcaatc tctagttttt gtaatgcagg gtttgatttg ttaggagaca
    16921 gtttagccaa tcaccagcaa aatgtttatt tgatcatggt ggtatctgct ttgatcattt
    16981 ctggtgggtt aggcttcatc gtatggcgtg atttactgga atatcatcag aaaaagaaga
    17041 tgacgattca ttcaaaaatc gcattaaccg ttacaggtac ccttttatta ggcggattcg
    17101 ttgtgttctt tttcacagag cgcaatgggg caacgctagt ggaagggaat atgtttcaac
    17161 gattggcaaa cacctttttt atgagtgtga cacctagaac ggctggatat tattcagttg
    17221 attacctcca tatgagccat gcaggtctga ttttaacgat gtttttgatg tacatcggcg
    17281 gaacatctgg gtcgacggcc ggcggattga aaacaactac gttaggtgtg ttgctgatcc
    17341 agatgcgttc gatgttgaaa ggacgtacga gagcggaagc atttggccgt accatccgac
    17401 aaggcgcagt gttgcgggca cttactttat tttttgttac gttgacgttg tgtgtagtcg
    17461 ccatcatgat tttatcggtg actgaaacga tacctaaaac ttctggcatc gaatatattg
    17521 cttttgaggt cttctctgcg tttggtacag taggtcttac gatgggattg acgccagact
    17581 tgactgcaat agggaaattg atcattatag cgcttatgta cattggacga gttggtgtat
    17641 tgactgtggt cttctctctg atgacaaaag cacaaagaac acaatcaaaa tacaaatatc
    17701 cagaagaaag tgtcatgatt ggataatttc atcttctgac agaaacctag tgatttagta
    17761 aaataagaaa ataaaataat ttttcttgct tcttggatac tttaagtgca aaatgttcgt
    17821 ttattttttg aggcactacc cgttgttgaa cctcgggtag tgcctctttt ttattgaaag
    17881 gaatcaataa gatttgattc ctttatttat caataggtta taattcatat ttttttattt
    17941 tttcttttac gatacttagt ccagaagcta aaatttcaag gttattagag gatagggaaa
    18001 ttcgaacgaa tgcatctggt tgcgcacgtg tagtaaagcg tctggaatga taaagtcgga
    18061 taccgttagc aagaaagtca ttctcaatta tcttagggtc aatctcagga tcaactggaa
    18121 gaattcgata gtaagggaca cgattcgttg gtttttctac tttgaaaaga gaatcaaaaa
    18181 gctgattggc tctttttgta agacttaatt tagtttctaa gatcctattt gcttcatttg
    18241 aatggaggat ttgagtgatg acttccacat ctaatccaga agttttcaca tttatattat
    18301 aaattgcttg ttctatcttg ctttggacat gtactggaac tacaagataa gcaactcgca
    18361 atccagaaca aataaatttt gtcattccag ctaagtagat tgtttggtta ggtaataaat
    18421 tttggaaagg aggaatgatc gtatgttgat agtaagttgt taaaaatgaa tggatatcat
    18481 cttcaataac ccatagacct tctttttcaa tcacttcggc taattgctct cgtcttttgt
    18541 gagagatttg aaaccctata ggattattac aagaaggcat aagaaagaca ccatgaatct
    18601 tcttttttct acattcctga atcaatatat caggtcgcat tccttgctcg tcaaaatcaa
    18661 ttggaacgat ctctaaatga tataactgag ccaattcaat gaaattagcg tatgtatatc
    18721 ggtctgttgc tattctatca cctggagaga aaagtgcaga aagtgtgata gccaatccat
    18781 tttgaacacc ggaaacaata gatagagatt ctaaggacgg aatgactcct tgagttttta
    18841 accaatttgc tgcagtagtc aattgaaaat ttgtgccttt gggatcttgg taattaagca
    18901 aaccaacaag atttgggtta ttactagttg attgaataaa cgggacaacg aatttattac
    18961 attcttcaaa agaactaacc agaccaaaat caatgatatg ttcggttact tcattggtag
    19021 agatggtgat ggactcaaag acattgggag aattaaatgt gccacttcca atattcgtat
    19081 acagcaaacc tttctcaatt ccatatttat aagccttgcc aacggtagta aaatttaaat
    19141 ctaaataatc agctagctct ctttgggagg gtaactgagt gtttttctgt aatttattct
    19201 ttaaaatatc ttgttctaat tgttgaatca acgatcgata ataaggacgc ttcaattttt
    19261 gtttgtctgg tcgccaagtt aacgggtaat tgtcataaga attaataggc attttctcca
    19321 ctccttaaaa ttgtatacca tacaatttta ccattgattg tattgatttt agaagttaat
    19381 cttttgtgag gagggaattg tctatgaaaa ttattaattt tgaggaagta gtagcttctt
    19441 ttagttttga agaagcgatt caagtaatga aaaaatgttt ttttgattat gaaagtggta
    19501 aaatcagcca aaatcctcga ttggtggaaa ttttacctga cggaaaaggc aaaaatatgt
    19561 ttgcgatgat gcctgcttat ttgggggaga acagatattt tggcacaaaa gtcattaccg
    19621 cttttccgga taatcatcag tatcatttac cttctcattt aggagagatt ttcttgtttg
    19681 atgctcaaaa cggactaccc aaagcattga taaacgcaaa tgcagtcacc tggattcgaa
    19741 cagctgctgt atctgcgctg gcaacagatt acttagcaaa tccgcatgca gaaacacttg
    19801 ctttaattgg agctggtcaa caagcattgt cgcatttgac tgcgatttct accattcgtc
    19861 ccatcactac agtgtttgtt tacgatattt tagaagaaag acgaaatact tttatcgcta
    19921 aagctaaaaa acagtatcct aaaataacgt ttataaatgc aatatcagta gaagatgcag
    19981 tacgtccagc ggaaatcatt tgtacgttga cctctagtaa agaggcattt cttcaaaaag
    20041 agtgggtaag ggaagacgca catatcaatg ctgtgggcac atttactcct gatacaagag
    20101 agataagtac atcgttgatg gaaacttctc aaatctatgt agatgattac tcagctgcct
    20161 taacagaaag cggggacctg cttatagcca tggcagaagg agatttagag gaatcttgta
    20221 ttgttggtac attaggcgaa ttagtttctg agaaaaaaac attttataaa ggagaatcga
    20281 ggccgacgat tttcgacgca gttggtctag ctattgaaga tctttgttgt gcagaatata
    20341 tttataacaa attagagaaa ggggctttaa aatgaactta gattattacg tagttgatgc
    20401 atttgcagat gaggtgttca aaggaaatcc agcagcggtt tatgtgctag aagaatggct
    20461 gccagaaggt acgatgcaaa aaattgccat tgaaaacaat ttatctgaaa cagcatttac
    20521 agtgaagaaa aaccaagaat ttgagcttag atggtttacg ccagatcgag aaatcgatct
    20581 ttgtggtcac gcgacattag caacagcatt tgttttattt aactattaca aaatacctga
    20641 tgaaacgatt aaattttcta ctcaaagcgg taatctattt gtgacaagaa ttaaagatta
    20701 ttattacatg gattttccta gtattatgcc gaaaaaagtg ccgatattgt ctgaatatga
    20761 agaagcgatt ggggctaaga ttaaagaagc ctacttagca cgtgatttat ttttcgtatt
    20821 agaagatgaa aaaacggtgg ctaaattgca gccagatttt acagctatca aaaattttga
    20881 attaggaata ggagtcatcg tgacagcaga aagtgtgcaa aaagactttg tttctagaac
    20941 cttctttcca aaattaacaa tcaatgaaga tccagtatgt ggatcagcac attctaatct
    21001 tattccttat tgggcagaaa gaatgaataa aacaaaattg tcagcttatc aaatgtcatc
    21061 aaggggcggg gatctagaat gtgaattaaa agaagatcgt gtgataatag gaggaaaagc
    21121 agttttgttt tctaaaggta cctcgtttat ttgatttctt tcaaatgaat taaaaataaa
    21181 ttggtggaga gtggcaacct tatagctaca atggttgtta aaaaaagacg caaacttttt
    21241 caatttaatg aaaagtttgc gtctcatttt aattattggt gtttgttttt tattcaatca
    21301 agagtaaaat gccccatact aactatcctc ggatgacttc gattttataa ccatcagggt
    21361 caatgacaaa gtagtaagaa ggcgcagtgc caggtaatcc ttttaagtca gtaatctcaa
    21421 gaccggcagc tttatgttgc tcgtgtaatt tttctagatc atcagctgct atagcgatat
    21481 gaccatagcc gtctcctaga tcatacgcac catgatcata gttgtaagtc aactctaatt
    21541 catagtcatc cccaggaagt gtcaaataaa caagtgtaaa tttgttttct ggaaaatcac
    21601 ggcggcggct ttcttcaaaa ccaaatgcct tttgataaaa ttcgattgat gcttcaagat
    21661 ctttcactcg aacacatgtg tgagccattt tcatagattc atctctcctt ttccttttac
    21721 tcaatcataa caaaaagaag taaggaaata gttgatttgt gcttgttcat gagaaatttc
    21781 tcatgtaaaa tggatagaaa ataaaactgt taaggtggaa actattcatg gataaaccaa
    21841 tttttggtga aaaaaagcaa tttgctgatt atcaaacccg ttatgcagca tatattgtca
    21901 tagaaagaga tcagcagatt gcagtaatcg aggctccaaa tggtgctttt tttcttcctg
    21961 gcggggaaat tgaaggagaa gagacgaaag aagaagcgat tgtccgtgag ctgatagaag
    22021 aaatgggaat tgtggcagaa atttcttctt atctgggaga agctgatgag tatttttact
    22081 cgaattatcg tgcaacttat tattataatc caggatattt ctttgttgct gattcttgga
    22141 agcgtatagg agaaccaact gaaaagacca ataaaatttg gtgggtgagc cctcaagaag
    22201 cgcttgtgaa attgaaacgt ggtagccacc gatgggcagt cgagagatgg atcgaaaaaa
    22261 ataaaaactg aaagaaagcg agtagatcag ctttctctca gtttttttat ttattacagt
    22321 acatattttt tgattgcttc agctacaccg tgctcgtcgt ttgatgaagt gatgacattt
    22381 gctgcttctt tgacaagaga aacggcattt cccattgcta ctcctagacc agcatattca
    22441 atcatggata agtcgttctc gttatctccg atagccatga tttcatcttg atcaatacca
    22501 aggtgctgtg cgagattcgc aactgccgca cctttacttg cttctttatt tagtacttcg
    22561 aagtaatagg gcgcactttt gaccgttgtg tatttatcac ggaaagtttg cggtaaacgc
    22621 gcaattgctg catctaaaat ttctggttcg tcgatcatca tcattttgac gatgttcatg
    22681 tctggtgtca tttcttcagg tgttcgatat tttagcggca tcttgactaa acttgcttcg
    22741 tggatcgtat aagcgctgat atctcgatta ggcgtgtaga tcgctttgtc atcgatcgaa
    22801 tggagatgac tgccgacacg gcgtgccatc acttcgatct ctaggaaatc ttcatgtgtc
    22861 agtccgtgac gggcgatgat tttacctgat ttcgtttgtt gtacgagtgc cccgttataa
    22921 gtaataacgt aatcattatc ttgaaaaagg ttcaactcgt ttaactgttc ctggacacct
    22981 ggtaagggac ggccagtgca taaaacgatc gaaacacctt ttgcaacagc agcggcaatc
    23041 gcttctttta cttcttttgt tacttctctt ttctcattta ataaagtacc atcgatgtcg
    23101 atagcgacta gtttgataga cataatttcc tccaatatat tttaatttat ttcaatcaat
    23161 gcgccattac ggatatggct ggcaaattct tgataagttt cgtcaaataa atcataatga
    23221 tcacgcaagg acggatcaac catttctttt ggaaagaaaa atcgctcatc tccttgttct
    23281 tgtcccgcta atgcagcaac aagctgacta acctgtgata attctatcaa agttccgtca
    23341 tttcgcaaaa tctcgatttg tgtgcgatgt ctgccttgtt ctgggcgata aaaatcataa
    23401 ggtagatcgt agctagaatt cacagcagtg taataaacag gattatatcc gaccttttct
    23461 actaacaaag tgagttcttg gactaatttt gaatcccggt tgccagaaaa agtagcagat
    23521 ttcagtggtt tacgattcaa aaaacgttta gctaaatcat ttaaaatagg atcagcagat
    23581 tcagaccatt gagtaaagta agtgcccaag accccatcat caagtttgag gtattcttct
    23641 aaagtaaagc ttccgtcaag aaatggcaga agtaattgag aatggagttc aaaactgctg
    23701 gcatcttctt gatacaactc gtgtgcgcga tgaagcagat gctccaaaat tacttccata
    23761 ccacgggaaa caggatggaa gtacacttgc acatacattt gatatcggct aacgatataa
    23821 tcttccactg catgcatgcc actcatggaa aaagcgatcc cgccttcata aggacgaatc
    23881 acacgtaata ttcgggtaag atcaaatgtt ccatattctg ttccagtgaa ataagcatcc
    23941 cgaagcaaat agtccattcg atctgcatcg atctgactag aaatcatttg gacaacttgt
    24001 gggttggggt aagttttttg gatcacacta gctacctttt caggaaaacc ttcttctact
    24061 cggttaagaa tctgatacac ttctgtttct ggagaagtga tgatctctac agtgatggct
    24121 tcatgattcg tatggaagat atgttcaaat gtatgagagt aaggaccatg accgacatca
    24181 tgcaacagtg ccgcacataa agtcaccagc cgttcctgat catcccagcc tccgttgcct
    24241 attttttctt ttgaaaaatt tcgagaaaag atatcgcaga ttcgtcttga aatctcataa
    24301 acgcctaatg aatgagtaaa acggctatgt tctgctccgt gaaaagtgaa agaagaagtg
    24361 cctaattgtt taatgcgtcg tagacgttgg acttctttcg aattgatcaa atctaagatt
    24421 acttgatgct ggacatggat atagttatgg actggatcac gaaaaacttt ttccataggc
    24481 agcatttgat atttataagg ggttgtcata atgtagctcc tttatgttat tacgttgttc
    24541 cattctctgg atttggttgt tccattgctc cagctggatt tcttttttta gccagtcggt
    24601 agaatcctgt aaatcacttg cagaatacag cttttcaaaa gcttttgcaa atgcttcttt
    24661 gacttctttt acaaaaaggg gttggtcaag cagttcttca agtgttgcca ttgtagcagg
    24721 atccactgca ggatagccat ttgtaccaaa gtcttctttt aaagcagatt gataaaatcg
    24781 cttcatgact tgcccgcgtt tttcctgatt accgttgaca cttaagtaca tcataacaga
    24841 aatcccattt ttgatccgac gctgagcgat accggcaaat tttttgccat ggatgcttaa
    24901 atcataagtt ccaggacaat aagaatgggt gatttcgaat gcttgtatcg gtgcctttgg
    24961 aaaagcgtat ttagtcaata ggagcatttg ctcgtaagcg tcatctatgg ttattttttt
    25021 tgtgtcactt tgggggaaaa tcaaagaaat attcaaaatt ccttcatctg atacgatccc
    25081 taatccacct gaatttctga tcactggagc gtaacctgca tctttcagtg tttggatccc
    25141 gtcacttaga aaaggagttc gaacatcctt catacctaag atgactgtgc agtcatattg
    25201 ccagaaatgt aaaaagattt gctggtgttc tttagaatat tccgttaata tatctgttaa
    25261 tgcaaaaggg gaaaagtcgt ttttttgata aatgtgctga tctagtcgaa tcgcagggtt
    25321 cattcaaccg gctcctttgt ataaattcat attttctaca atattatact ctaaaatcaa
    25381 agagttgttt tggaaaaaag gttttctgta aaaatggaca agttggttga caaaacaaaa
    25441 gaaactagga acaatgtagc tatgagaagt aaaggagaat gaataatgga attatcacaa
    25501 ggaacaccga tttcaatcaa attgcgtaca aaagtaaaac agcaagggga agtgcaagat
    25561 ttttattttg atttgaaagg gcaaatggtg acaattggcg atacgctgta catacgttat
    25621 aaagagattc aggaggagac gggcgatgag attcctgtaa cgatcaaatt agttccagat
    25681 ggtcatgtac agctgatccg tgcaggagaa atgcggatgc gtttgaaatt tggctataaa
    25741 gaacggttag aaacatccta tcgaacacca tacggtatga tccagattgc tacttttacg
    25801 aaagaactgc atgttagttt gaaagaccgt cccacaggag ggaaggttcg aatcgattat
    25861 gatctgttca tgggaccgga aaaaatcggc gaatattatt tgaccttgga ttttacagcg
    25921 taaatataaa agaaaagttt gattttttgt gtctgatttt gtatgataag gagtagactg
    25981 tgaaaggacg tgtcctgatt ggaaattagt gtatttgaag gtgcaaacaa aagcgaatta
    26041 tcaatgatcg aagtagcaca cgcgatctta gaacaacgtg gcgatgtcat ggatttttct
    26101 gatttagcta accagatcca aaactatctt gggaaatcag acagtgaaat tcgtgattca
    26161 ctcgcacaat tttatactga cttgaatatt gacggcagct ttatctcatt aggggataat
    26221 cgttggggct tgcgttcatg gtatgctatc gattcgatcg atgaagaagt aaaccatgga
    26281 atggacgaag aggatgaaga tactccacgt cgccgtaaac gcaagaaagt caacgccttt
    26341 atcaatgatg atgaagacgc gatcgattac aatgacgatg acccagaaga tacagatctg
    26401 acagaagaag atgacgatga tctgtttgat gacgatgatg atgaagatga agaaatcgct
    26461 gcttataatt ctgacttgca agaaatcgga gcagatgacc cgacagatga tgaagaagac
    26521 ttgccaggaa atatcgaaga agatttaagt atcatagacg aagacgatga tgatgaagat
    26581 tatgaagagg aagaattttc tgactctgaa aaagaataaa cattattttc ttacgagagg
    26641 ttgtgacaga gacgatcagc ctatcagaat aaggaggtgt gacacgattt ttgtcacacc
    26701 ttcttttttg tatataaaaa tcccaagtaa atacataaaa aataaaaaaa ttgaaacttt
    26761 tagcgcacct tgtacgtcat attaagtgag gcagaaagga gtggagaatg atttttactg
    26821 gatataagaa aaaacggcag atcgaaaaat accgtcacct gctgaatgga ctcatcgaaa
    26881 ctgattatca aaaaatgttc cgtatcacga tgaattacgt acatgataaa gaagaggcct
    26941 tagatgtgat gcaagatagt tttcataaag ccctgaacta ttttgaaaaa gaaaaagaga
    27001 tcgagcattt tagtgcatgg ttttatcgga tattgatccg cacggcatta gatagttggc
    27061 gcagacaaaa aaggacgcct gtggacttat ttgaaattca agatatcccc caacagttac
    27121 ctttagaaac ttccgttgca gagctccata tgattttaga taaaatagac agtccggaaa
    27181 aagagattct gatcctctac ttttttgaag gatttcgttt gaaagaaatt gcgactatct
    27241 tggatatgaa tgaaaacaca gttaaaacga aaatgtaccg ctcattgaat gctttacgtc
    27301 aaatcctaga atgaaggaga gaagagtgcc atgtattccc aaaaagaaaa tttaaaaaaa
    27361 ctaaagaaaa cttataaaga acaagcaatt cccaaagggc ttaaagagga gatccgccag
    27421 cgttttatta tcgaagagca atcatttata aaagcaaagc ggagaaagag acgtctccaa
    27481 gggttcggag tatctttggc tatcgtaatg attacaacaa gtagccttct ttttaatagt
    27541 caagttcgaa gctttgcaga agatttaccc atcttaggat cagtcattga attgatctta
    27601 ggcgaacgct ttactgatcg atctgaaaaa atcgatattc aggtaccgaa gatcaataca
    27661 caaaatgaga aagaaaataa aacaattcat ggattaaatc aaaaatactt tcgcgaagga
    27721 caagcagatt ttgaaaaagc tgaaaaagaa tatggaaatt ttgaaacgga tcattaccaa
    27781 gttttgggag attatcagaa aatcgtagac gataaccggt ttctcgtgat tgaaaggcag
    27841 atcacccaaa cagcagcaga tagccatgtt gaaaaaagat acgacacaat cgacaagaaa
    27901 aacagtgtcc agctctcact tccactttta ttcaaagatg acacctatct atctgttttg
    27961 acaaaagaag tcaaacggca gatggccgaa caagtcaagg aagatccatc taagtactat
    28021 tggactgagc aagatattca agaagggacg atagaaaaac caacacttgt tacgcctaca
    28081 cgaagttttt atttgaacaa agagcatcaa ttagttttga ctttttctca atacgaaatt
    28141 gctcctggtt atatgggtac accagaattt gtcattccta agtccgtgac aaaaacgatt
    28201 ttggcatcgg aagattattt ggatcattag acgagaagta gttgcgacta gcagtttcaa
    28261 ttttcaagta agtacaagta aataataaga agagaaaaag agaaagaaga gatatagtga
    28321 aaagaaatta tttagttatc agtattattg ctttatccgt gcttttgttt ttcgaaatta
    28381 cttcggtggc ctccttgatc accgaagtaa aaggacaaac acactcttcg gagcattcgt
    28441 cacaatcttt caaacaatca gaacaatcaa ccattaaaag ccaatcaact gaaacagcta
    28501 acgtcaaaga agccattcaa gaatcagcgg aaaaggtaca aagtcagtca tcacaatcaa
    28561 cacaagacag tacaaaaacg agccgagatc cggctgtcaa aagcgtcgca atcagctttg
    28621 atgatggacc aggagcgacc acaacaccgc agcttctgcg aatcttaaaa gaaaaaaacg
    28681 tgcatgccac ttttttcgtc ttaggagaaa atacggcgca gcatcctgaa atcgtgaagc
    28741 agacagctga agcagggcac gagattggca atcacacata cgatcatcag aatctggcca
    28801 ctctttctgc ccagtcgatg acggaggaag tgacgaaagc agacactgag atcaaaaaag
    28861 tcactggcaa aacccccact tttgttcgtc cgccctatgg ttctgtcacg aatgtaggag
    28921 caacgatcat ccagcgaccg atcatcgaat ggtctgttga ttcagaagat tggaagacaa
    28981 gaaatcctga tttgattttg cagaagatcc aagcaacagt atacgatggg gcaattattt
    29041 tattccatga tatctatcct gaaacgattc gtgccgttcc tcaagtgatc gattatctga
    29101 aagagcaagg gtatcgcatc acgacagttg gggatttatt agggcatcca acggctgtcg
    29161 agaactatta tggcagaaac gatcatcggc cagttcagta agtgagacaa gtatctttaa
    29221 taaataacac attttaataa gtagttgaac acataactac cttacttgca aaggcttaac
    29281 aatatctata caggtacaac aaaaaactgt ccaccaattt tctttggcgg acagttttca
    29341 cttaaaaata aagaagcaac tattcgtaaa ttatgctaaa atagcagtag aacgcgtcct
    29401 gagggaatcg aacccccgtc tcaagaaccg gaatcttacg tgatatccac tacactaagg
    29461 acgcaagcac tgggataatt gtaactaaac agataaaaaa ttacaagggg attggacaaa
    29521 aaaatgaaat ttgagcaaaa tttttcacaa aaacagcagc agacacagaa actaaccatg
    29581 acgcaacagt tgcaacagtc catccaagtt ttacaatata acagtgagga gctgttggca
    29641 ttcgttgaga atcaagcaat ggaaaatcca ttggtggaag ttgttgagcc ggaatggcag
    29701 ccagattaca taaaagcttc ttcatcttct tatgaaggag aagagacaaa ttacctaaat
    29761 cagattcctg atacaaaagg gtctttattt gattcattga tcgaacaagt ccatttgaat
    29821 taccgagata cttttttgag gaaaatcgtt ctttatcttg tagaatacat cgatttgaac
    29881 ggatttttga cgattagttt agaagaagcc ggaaaagaga ttggagctac gcctatccaa
    29941 atgctcgatg cgttgactct gattcagcaa ttagaaccag ctggagtagg tgcacgtagt
    30001 ttgcaagaat gtctcatgct tcaaacagaa cgagatgatt atgcgccgga attagcttat
    30061 atcgtgttgg aagaatgttt tgaggaactg gtggagcgaa aatggaaaga aatcgcacaa
    30121 cgtttttctg ttgatctaca tgctgttcag cagatattcg actatttaca aacgttgagt
    30181 ccaagccctg gccggatttt cgaccgtagc agcgaattgt acattattcc tgatgtccgg
    30241 gtattagtgg acgacgataa aaatgtacaa gttatctcaa accgaaaaaa tcagccaaat
    30301 atacgctttc aagagagtta cttcaaacaa atgtcacaac aagcagataa agaaactgaa
    30361 aattatttaa aagaacggaa acaggaattc gaatggttga agaaaacgat cctacaacgt
    30421 ggggatacaa ttttgcgggt tgctcaagtc attgtttccc ggcaaaaagc tttctttatc
    30481 gacaaggaac gtccaatcaa gcctcttacg ttaaaggaag ttgcaactga gatagatgtg
    30541 catgaatcca cggtcagtcg tgcagtcaac gggaaatatt tggaaacaga cttcggtgta
    30601 tttgaattaa aaaaattttt cactacacga attcctacga atagtacaga acagacagaa
    30661 gacctttcag cagatacagc gaagaaaaag ctgcaggaat tagtcgatca agaagacaaa
    30721 aacaagccgt tgtctgacca gaaattggtt gaattgctga aaaaagatga gatagcgatc
    30781 tcaagacgaa cagtagcaaa atatcgtgat ttattaggaa tcccgagttc atcaaaaaga
    30841 aaacgttatg ataactaatc agtcaaaaga ctagaaaaag tatttcactt tttctagtct
    30901 ttttagttga aaaacgagag caaaactgtt agacttacag tcgtgaggtt gagatttccc
    30961 tttattgatg tgaaattcga atagttaatt tcttttttta tcgtatatgg gtcgttttaa
    31021 gtctacattg gacgtaaagt gtccaactaa ggagatcgct atgttggatg aaataaaaat
    31081 gattgaatct gttgcaccag atattatcga agtgttgcaa gaacgctata aaattttacg
    31141 aaatatctat tggatgcagc cgattggacg tcgaagttta tcggaaagta tggggatcac
    31201 agaacgagta ttgcgaacag aaacagatct tttgaaaaat ctgaatttga tcgacacctc
    31261 aaaaagcggt atgacgctga caactaaggg cgaagaagtt tatcaaagcc ttgaaaactt
    31321 catggatcag cttttaggta cgcatcaaac cgaacaacag ttggcagaat attttggtaa
    31381 ccaacgctgt atcgttgttt caggaaacag cgaagagcag accaaagtgg ctgatgcatt
    31441 cggcgaagcg ctgagcgaag ccctagaccg actacttcca gaaggcgaga atatcatcgc
    31501 tgtgatggga ggaactacta tggctgtggt agccgaacaa ttgtctaatc tggaaaataa
    31561 gaaacggcat aacctgtttg tccctgcaag aggcgggatt ggtgaagcga taactgtaca
    31621 ggcaaattct gtcagtgcaa gaatggctgc taaagcaaac ggtaaccacc gtgcacttta
    31681 tgttccggaa caattaagtc tggcaactta caattcttta ctcaatgagc catctatcca
    31741 agaagtctta aacttgatta gtgaagcgaa ttgtgttatt catagtattg ggcgtgcatt
    31801 acacatggca gcacgtcgta agatgactga aaaagaatta gtcatgctga aacaagcaaa
    31861 tgctgttgcg gaatcttttg gctacttttt caatgaaaaa ggtgaagtcg tttataaggt
    31921 ccctagaatc ggcatagaat tgcaagattt ggaaaaagtc ccgatcatca tggcaatcgc
    31981 gggcggaaaa tcaaaagcca aagcaattcg agcttatatg aaaaatgcac caaaacaaac
    32041 gtggctcatc actgatgaag ctgctgcaaa tgagatttta aaaggggtaa ccctttaaaa
    32101 taaatatttt tttgattttc ataaggagga aatcttaaat gacagttaaa gtaggtatta
    32161 atggttttgg acgtattgga cgtctagcat tccgtcgtat ccaagatgta gatggaatcg
    32221 aagtagtagc aatcaacgac ttgacagatg ctaaaatgtt ggcacacttg ttaaaatacg
    32281 acacaactca aggacgtttc aacggaacag ttgaagttca tgaaggttca ttcaacgtaa
    32341 acggaaaaga agttaaagta ttagctaacc gcaacccaga agaattacca tggggcgaac
    32401 taggcgtaga tatcgttcta gaatgtactg gtttcttcac ttctaaatca gcagctgaaa
    32461 aacatttaac agctggtgct aaacgcgttg ttatctctgc tcctggcgga aacgatgttc
    32521 caacaatcgt ttataacaca aaccacgaaa cattaactgg taaagaaaca gttatctcag
    32581 gtgcttcatg tactactaac tgtttagctc ctatggctaa aacattgaac gacaaatttg
    32641 gtgttgttga aggattaatg acaactatcc acgcttacac aggtgaccaa atgactctag
    32701 acggacctca tcctaaaggt gacttccgcc gtgcacgcgc tgctgctgca aacatcgttc
    32761 ctaactcaac aggtgctgct aaagctatcg gtttagtaat tcctgaattg aacggtaaat
    32821 tagacggagc tgctcaacgt gttcctgtac caacaggttc attaacagaa ttagtaacag
    32881 ttcttgaaaa agaagtaact gttgacgaaa tcaatgcagc aatgaaagaa gcttcaaacg
    32941 aatcttacgg atacaacaca gacgaaatcg tttcttcaga tatcgttggt atgacttacg
    33001 gttcattatt tgatgctaca caaactaaag taatgacagt tggcgacaaa caattagtta
    33061 aaactgttgc ttggtacgac aacgaaatgt catacactgc acaattagta cgtactttag
    33121 aatacttcgc taacttataa gatagacaaa cgtacaagtg taaattatag acatgtacat
    33181 ttaaaagcgg ggaagcaatc gcgcttcttc cgcttttttt gataataagt ttattcagga
    33241 ggaaataaaa tggctaagaa aacagtgaaa gatatcgatt taaaagacaa aaaagttctt
    33301 gtccgtgttg acttcaacgt tcctttgaaa gacggcgtga tcactgacga cactcgtatc
    33361 aaagcagcat tgccaacaat caactacgtt ctagaacaag gcggaaaagc aatccttttc
    33421 tctcaccttg gacgtgtaaa aacagaagaa gataaagaag gaaaatcttt agctccagtt
    33481 gcaaaacgtc taggcgaatt attaggtaaa gaagtaacat tcgtacctga aactcgcgga
    33541 gaacaattag aagaagcaat ccgcaacatg aatgacggcg acgttgtcgt attcgaaaat
    33601 acacgatttg aagatattga cggtaaaaaa gaaagcaaaa atgatacaga actaggtaaa
    33661 tactgggctt cattaggcga tgtatttgtt aacgatgctt tcggtacagc tcaccgtgca
    33721 catgcttcta acgtaggtat cgcttcaact ggtatcccaa cagttgctgg attcttgatg
    33781 gaaaaagaaa tcaagttcat cggtgaagca gtagaagaac caaaacgacc aatgattgca
    33841 atccttggtg gcgcaaaagt ttctgataaa atcggcgtaa tcgaaaactt gattcctaaa
    33901 gcagataaaa tcttgatcgg tggcggaatg acttacacat tctacgaagc aaaaggaatc
    33961 aagatcggta actctctagt agaagctgat aaagtggaac tagcaaaaga attaatcgaa
    34021 aaagcaggcg acaaacttgt cttgccaatc gacaatgtct gtgcaccaga attttcaaat
    34081 gatgttgaaa cacaagtaat cgaaggagac attcctgatg gtttgatggc tttagacatc
    34141 ggcccagcat cagtaaaatt atttgctgat acattacaag gtgcaaaaac agttgtttgg
    34201 aacggaccta tgggtgtatt tgaaatgagt aactttgcta aaggtacaat cggtgtttgt
    34261 gaagcaatcg ctaacttaga aggcgcaaca acaatcatcg gtggcggaga ctcagccgca
    34321 gcagcagaac aattaggatt tgctgacaaa ttcacacaca tctcaacagg tggcggcgca
    34381 agcttggaat tgcttgaagg taaagaatta ccaggactag cagcaatcaa cgataaataa
    34441 acgaccaagt ttgctcaatt ctgacgagta atcgatcaaa aggtgaaggg agttttcatg
    34501 actccctagc catttttcaa taaattaagg agtgtgttcc tcaatgcgta aacctattat
    34561 cgcaggtaac tggaaaatga acaaaactgc atcagaagca aaagaatttg ctgaagcagt
    34621 aaaaaacaaa atcccttcaa atgacaaagt tgattcagtc atcggatctc ctgcattatt
    34681 cttacaagaa ttaatgacat cagctgaagg tacagaacta aaaatctcag cacaaaactg
    34741 ctactgggaa aactcaggtg cgttcactgg tgaaacttca ccagcagctc ttgctgatct
    34801 aggtgttcat tatgtgatca tcggacattc agaacgtcgt gaatatttcc atgaaacaga
    34861 cgaagacatc aataaaaaag cgaaagctat ctttgcaaat ggtatgacac caatcctatg
    34921 ctgtggcgaa tctttagaaa cctatgaagc aggcaaaact gctgaatgga tcgaaggaca
    34981 aattacagct ggtttagctg atctttcagc tgaacaagtg tcaaacatgg ttattgctta
    35041 tgaaccaatc tgggcaatcg gtactggtaa atcagctgac gcacaaatcg ctgacgaaat
    35101 ttgtggagtt gtacgtcaaa cagttgaaaa actttatgga aaagaagtat cagaagcagt
    35161 tcgtatccaa tacggcggtt ctgtaaaacc agaaaatatt gctgaataca tggcaaaaga
    35221 aaatgttgac ggtgctttag tcggtggcgc aagcttgcaa gcagattcat tcttgtcatt
    35281 gttagacgct gtaaaataat tgttgaaaat ttgcgaaaaa tgcaagaaat gtttgcacta
    35341 atgagcaaaa ttaactaaaa tcgtatatga gggaaatccc ttaggaaaaa acaaactcaa
    35401 aggagagaca aaacatgtca attattactg atgtttacgc tcgcgagatc ttagactcac
    35461 gtggtaaccc aacaatcgaa gtagaagtat acacagaaag cggagctttt ggccgcggaa
    35521 tggttccttc aggtgcttca actggtgaat acgaagcagt tgaattacgt gacggagaca
    35581 aagctcgtta tggcggtaaa ggtgtaacta aagctgtcga caacgtaaac aacatcattg
    35641 ctgaagcaat cattggctac gatgttcgtg accaaatggc tatcgacaaa gctatgatcg
    35701 ctttagacgg aactcctaac aaaggtaaat taggtgcgaa cgctatttta ggtgtttcta
    35761 tcgctgttgc acgtgcagct gctgactacc tagaagtacc tttataccac tacctaggcg
    35821 gattcaacac aaaagtattg ccaacaccaa tgatgaacat catcaacggc ggatcacatg
    35881 ctgataactc aatcgacttc caagaattca tgatcatgcc tgttggcgct ccaacattca
    35941 aagaagctct acgtatgggt gctgaagtat tccacgcatt agcttcaatc ttgaaagctc
    36001 gcggattagc aacttctgtt ggtgacgaag gtggatttgc tccaaacctt ggttcaaacg
    36061 aagaaggttt tgaagtaatc atcgaagcaa tcgaaaaagc tggctatgta cctggtaaag
    36121 acgttgttct tgctatggat gctgcttctt cagaattcta cgacaaagaa aaaggtgttt
    36181 acgtactagc tgattcaggc gaaggcgaaa aaacaactga cgaaatgatc aaattctacg
    36241 aagaattagt ttctaaatat ccaatcatct caatcgaaga cggattagac gaaaacgact
    36301 gggacggatt caagaaatta actgacgtat taggcgacaa agttcaatta gttggtgacg
    36361 acttgttcgt aacaaacact caaaaattat ctgaaggtat cgaaaaagga attgctaact
    36421 caatccttat caaagtgaac caaatcggta cattaacaga aactttcgaa gctatcgaaa
    36481 tggctaaaga agctggctac acagcagttg tatctcaccg ttctggtgaa acagaagatt
    36541 caacaatctc tgatatcgct gttgcaacaa acgctggcca aatcaaaact ggttctctat
    36601 cacgtactga ccgtattgct aaatacaacc aattactacg tatcgaagac caacttggtg
    36661 aagttgcaga atacaaaggt ttgaaatctt tctacaactt aaaaaacaaa taattctttt
    36721 ctaatgaaga tacatgatcg actattgaaa gatagtcgag tatgatcact tagttaagta
    36781 atcgaactct ctacttgctg aaatatcagc aggtagag
//
LOCUS       DAFEIE010000026        35719 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFEIE010000026
VERSION     DAFEIE010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.026"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..705)
                     /locus_tag="LP345_001399"
     CDS             complement(<1..705)
                     /locus_tag="LP345_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL1760185.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFI"
     gene            1393..1551
                     /locus_tag="LP345_001400"
     CDS             1393..1551
                     /locus_tag="LP345_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760186.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            1623..2849
                     /locus_tag="LP345_001401"
     CDS             1623..2849
                     /locus_tag="LP345_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1760187.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="LP345_001402"
     CDS             complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="LP345_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL1760188.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="LP345_001403"
     CDS             complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="LP345_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBL1760189.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4308..4775)
                     /locus_tag="LP345_001404"
     CDS             complement(4308..4775)
                     /locus_tag="LP345_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBL1760190.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(4895..6433)
                     /locus_tag="LP345_001405"
     CDS             complement(4895..6433)
                     /locus_tag="LP345_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBL1760191.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            6513..7199
                     /locus_tag="LP345_001406"
     CDS             6513..7199
                     /locus_tag="LP345_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBL1760192.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="LP345_001407"
     CDS             complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="LP345_001407"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL1760193.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="LP345_001408"
     CDS             complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="LP345_001408"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL1760194.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(8685..9815)
                     /locus_tag="LP345_001409"
     CDS             complement(8685..9815)
                     /locus_tag="LP345_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL1760195.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(9815..11998)
                     /locus_tag="LP345_001410"
     CDS             complement(9815..11998)
                     /locus_tag="LP345_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL1760196.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(11995..13020)
                     /locus_tag="LP345_001411"
     CDS             complement(11995..13020)
                     /locus_tag="LP345_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1760197.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13065..13892)
                     /locus_tag="LP345_001412"
     CDS             complement(13065..13892)
                     /locus_tag="LP345_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL1760198.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(13889..14956)
                     /locus_tag="LP345_001413"
     CDS             complement(13889..14956)
                     /locus_tag="LP345_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBL1760199.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(14982..15818)
                     /locus_tag="LP345_001414"
     CDS             complement(14982..15818)
                     /locus_tag="LP345_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1760200.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(15815..16684)
                     /locus_tag="LP345_001415"
     CDS             complement(15815..16684)
                     /locus_tag="LP345_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1760201.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(16754..18037)
                     /locus_tag="LP345_001416"
     CDS             complement(16754..18037)
                     /locus_tag="LP345_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBL1760202.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18051..19736)
                     /locus_tag="LP345_001417"
     CDS             complement(18051..19736)
                     /locus_tag="LP345_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBL1760203.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20011..21036
                     /locus_tag="LP345_001418"
     CDS             20011..21036
                     /locus_tag="LP345_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1760204.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="LP345_001419"
     CDS             complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="LP345_001419"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBL1760205.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="LP345_001420"
     CDS             complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="LP345_001420"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL1760206.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            29708..30676
                     /locus_tag="LP345_001421"
     CDS             29708..30676
                     /locus_tag="LP345_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1760207.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            30694..31599
                     /locus_tag="LP345_001422"
     CDS             30694..31599
                     /locus_tag="LP345_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760208.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            31596..32402
                     /locus_tag="LP345_001423"
     CDS             31596..32402
                     /locus_tag="LP345_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1760209.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            32538..33527
                     /locus_tag="LP345_001424"
     CDS             32538..33527
                     /locus_tag="LP345_001424"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBL1760210.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(33844..34368)
                     /locus_tag="LP345_001425"
     CDS             complement(33844..34368)
                     /locus_tag="LP345_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBL1760211.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            34655..>35719
                     /gene="scm"
                     /locus_tag="LP345_001426"
     CDS             34655..>35719
                     /gene="scm"
                     /locus_tag="LP345_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBL1760212.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        10272 a         7539 c         6612 g        11296 t
ORIGIN      
        1 aataaatata gtatctccat aggctttttt taaattctct tcattaaata cagattctac
       61 acttccgtga gcaattagat ttcgattcaa aagaataata ttatcaaaat acttctttac
      121 cttgcttaaa tcatgatgca caattagcac tgtttttccc tgatgtttca attcttttaa
      181 cgtatccata attattcgtt cactaactaa gtctatccct acaaatggtt catctaaaaa
      241 tatgaaatcc gcattttgag caagacatct tgctaaaagt acacgttgaa attgtcctcc
      301 agataattct cctatttgat gattagaata ttttcccata tcgacctttt ccaaagcctt
      361 tgaaactctt tgccattctg catttttaat tctttgaaaa actttcattc cggcatatgt
      421 tcccatagat acacattctt ttacttttat tggaaaagta aaatcaatat cagctttttg
      481 ctctacatat gcaatcttca ccagtttttt attgatatct tcattattaa tggagacctc
      541 tccctgatga gggataatat ttaacattgc tttaagcaat gtagattttc cagcaccatt
      601 tggaccaata atacctgtta aagcaccttc ttgtattttt aaagaaatct cgttcaatgc
      661 taaaaaatcg ttataacaaa cattaagctt tttcacttct aacataactt tctccttcta
      721 aatgataatg attatcacga tcatatggta tacaaaaatt atattttagt caaccctaaa
      781 ttttataatt tagatttttt tctgttgctg aagattagaa tgacaaaact atttgaaact
      841 acgcgtatag taagtagctt tcaaaatata taaaaaagga gcgttctcaa atgagaacat
      901 gctcctaaaa ctactttatt ggcgtatgga aaaattatac ttaaagtgga tagcgggttg
      961 aataagttga taagcatcaa aacatttata aaaattattc aagactatgt ctgttccata
     1021 tacaaatatg aaaatcagta aactccattt aacttttttc gtagtgtgtc tttttataca
     1081 tgtttatcgt tattaatagt gaataggaaa aaacctattt ttgatcattg acaattaaat
     1141 acaatttttg aataacgatc cctgctattc gagctagaaa ctcaagtacg ccatgacctg
     1201 attagcgaca aatacttaga gatttctttt tgttctggga aaacaaaatg ccatgacaat
     1261 agcagcaaat aatgatactt ccgtaaggct cgccgtaaac tggggagagg tgaaattcct
     1321 atgtgcttac ccaaagcaat tcaaaaattc taatcttttt taggagatga ttttataaaa
     1381 ttgagagtct acttgaataa aaaacaaacc tgtgagtttc taggaattga taataatact
     1441 ttagataagt ggattcgtat atataatttt ccagtaatca gaattgacgg tatagttcgc
     1501 tttgacatag aggatatcaa agattttatg aatacattta aaacaatttg aaaatttctt
     1561 ctcgccgcat atactaagaa tagcgaaata tactgcctta ctttttaagg gagtgaggaa
     1621 ttttgcctac aaaactttca aatgggaaat ataaaactaa tctgaggtat ccaaaaaaat
     1681 tcagagaaat cactggaatt acatcagaaa agtatcaaaa agtatttcca actaggcaat
     1741 tggctattaa agccgaaaat gcaatgaaaa ggaaaattga aacagtttta agagaggaga
     1801 atgcaaattc actagaatta aaaggaaaaa taaaatttaa ggaattctat gaatcaaaat
     1861 ggcttcctag atatgaacta ggtcagacta ctagatcaaa aagagctcca agttacgtaa
     1921 caattagtaa tactaaagat atattccgat tgcacatcct tccaatgttt ggtgagtatg
     1981 caatgaacta tctaaattca aatactgaga taatatcaga tgaattaaca aaaaaatcga
     2041 aagaatacgc aaatataaaa attatcaaag gatatgtccg ttctatgttt gatattgcag
     2101 aaatactaaa ttatattgaa tttaaccgaa ctaccaaaat tattcaatgt atcactgcac
     2161 ctaaaaaaat tgctttagaa gaaagaagga tacgggaagg taatcaagca ttatcgtcag
     2221 aagagcttat tgcttggata gaagcagtaa acactgactt gaataatcac ttgcttactc
     2281 ttcatgacta tactcttttc atgcttaccc tatatcttgg tgatagaaaa agtgagacgt
     2341 atgctttgca atggaaatat atcgactttg agaaacaaac ggttcgcctt aaacatgctt
     2401 tggataaata tcaaaaaaag aaatttacaa aaggtcgaaa ggataccgta attcaagtac
     2461 ccgaaattgt aatggcatta ctaagcaaat ggaaatcagt gcaagctgag caattgttga
     2521 gattaaaaat taatcaaaca ccagatcagt atctctttac ctatactaaa ccatccggag
     2581 aagtaaattg ccctgttcac gctgattacc taaactatcg aatcaattca attaaaagac
     2641 gacatcctga attggctcat ttatctccac ataagcttcg tcatacctat gcaactatag
     2701 ctagacaagg cggagcaaat atgaatcaaa tatctagtgc tttaacacac tcagatattt
     2761 ctacaacgag aatatacgta aatacaccag atgtagtaga taaaactgtt tttgaagcct
     2821 ttcagagagg attgaataaa tgtgattagt atgtgttctt aaatgtgttc ttaaacaaga
     2881 aaaagacact tttcaaacaa ttgaaaagtg ccttgaaaca ttgatatata aataatatta
     2941 acgtttagag aattgagatg ctttacgagc ctttttgaga cctggttttt tacgttcgac
     3001 catacgtgcg tcacgagtaa gtaagccagc acgtttaaga gctaaacgga agtcaggatc
     3061 aacttctagc aatgcacgag cgataccatg acggatagct cctgattgtc cagcgtatcc
     3121 tccgccgttt acgttaacaa atacgtcata tgcgcctttt gtttcagtaa cagcgaaagg
     3181 ttgattgatt acttcacgca agtcagcatg tggaatgtat tcttcaacat cttttttatt
     3241 tacagtaatt ttgccagttc ctggtactag acgtacgcga gcaactgcgt ttttacgacg
     3301 gcctgtgccg atatattgaa cttgtgccaa tgaaattccc tcctattaga ttaagtttgt
     3361 gatgtctaaa acttctggtt gttgtgctgc atgtggatgt tctgctccac cgtatacgtt
     3421 caattttgta aattgtttgc ggcctaaagt gtttttagga agcatacctt ttacagaagt
     3481 ttcgatcaaa cgacgagaat ttttagcacg caattcgcca gcagtgattg atttcaatcc
     3541 tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc gcttttttac ctgttaattt
     3601 cactttgtct gcattgatga cgatgacgaa atcaccagta tccaaatgag gtgtgaaagt
     3661 tggtttattt ttaccacgta gtacagatgc aacaactgtt gaaagacgtc ccaatggaac
     3721 atcagttgcg tctactacat accatttacg ttctacttcg cctggtttgg ccatatatgt
     3781 tgtacgcacg ttattttcct ccaatttaag ttctgatgtt tgacatacac ttcgagtttc
     3841 cggggctctt tgtggggcaa acaataccat ttaacatatt acccgctaat ctagtcaatg
     3901 tcaacgtttt tctgcttgat tgaaaaattt atatgaaact ttacttcttt tctttctttt
     3961 atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa gaggctgtga caaaagtctt
     4021 gtcacaaccc cttattttga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca
     4081 caatatccat aaaacataag aagctgtttt ttaaaattgt ttcttgtgac tcggagctga
     4141 acggcaggct tacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
     4201 caaaaaacgg caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa
     4261 aacgctgatt tcacaacctc tttttcggtc aagttcaaca acagttttta cgcgtcgatc
     4321 tctggcgctt tgcccaaatg agcttggatc atccagatac gtttttctgt ggctgttttg
     4381 aattcgataa agatatcttg tgttggatcg tcgccttctt ctccagaaac ttcgattcct
     4441 ttttggtaaa gatctgctag ataacgatag cctgcaacaa gtgtttccaa acgttctgga
     4501 atagtacgat cccagcggcc aatttcatca gggatttttg tgttatctgc aaattcacgc
     4561 aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt cggatacttc atctaactga
     4621 gcgttcaaat catccatgaa ctcatccatc attgggtgca atgtaaggaa acctggtcct
     4681 ctcatgtacc aatgtgtttg gtgaacaaca acagacattt ggcttagatc tgcaactaat
     4741 tgatttaata cttctttggt ttgttggaat ttcatctttc ttgcctccta acattttctt
     4801 acacttaaaa taatagtaga ctttcaatga aaagtacaac aaaatcattt acctgagaac
     4861 gattttcagt tcgctttttt atccgtaaag ccaatcattt ttcagaatca gctaattctt
     4921 ctcgcagttg agcaaattgc tgataagtct gtgctaaatg cttttgtgtc gaaacaaata
     4981 atggatagat tttctgatat tttttatgat cagtttcttg tactccaact tgctctttca
     5041 attctatcaa ttcctgtgct tcactgatac tttggatctt tccgatgctt ctccagccta
     5101 aaatcacagc tcctaatgcg gatgcttctg tgacagtagg gaaaacaagc gggtaaccca
     5161 gtacatcagc catcatctga cgaaaaatcg gagattgagc aaacccgcct gtagcacgga
     5221 tctctgtgag ctgattttcc tggcaaactc cttttaaaat ccgataaagg ttgagacaga
     5281 tcccttctag aatcgccttc atcatttctt tttctgtatg ttgccgctgt aaaccgataa
     5341 aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc accaagtaaa tagggatgaa
     5401 aaatcagacc attggcaccc gctggcacaa aagcgatagc cgaaagcagt gcatcatatg
     5461 gattttctcc tttttcttta gcagattgaa cgacttcctg taaaaatgta tgccctgccc
     5521 aatcaaagat gccagcacca ttgctagtcg ctcctcccac tacccaatgt ttctgatcca
     5581 gaacataaca aaacgtctcc atttctggat ggaactgagg ctgagtagta ataaaacgaa
     5641 gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc accaaaagca cctaacccta
     5701 gattagaaag cggcccgtct gcccctccca aaacaaatga tatatcattt ggcaaaccta
     5761 gttctgctgc tgtttttgat ggtagacctg ttacttgata ggtggaagga aagacttgcg
     5821 gcaattgctc tattcgaatg ttcaagtagt caagcacttc ttctgcccat tggaattcat
     5881 ggatatcaaa atatccagtt cctgaagctg ttccgtagtc gctgatcagt tcgccaaaca
     5941 atctataaaa gatatagtct ttgataccga caaaataagc agtttttttg aataattcag
     6001 gttggctgtt ttgcagccac ttgattttgt tcaatggtgt cattggatga atcggcgtcc
     6061 cagtctgccg ataaaattct ttgccaagca cggtatattt cagtttttct gcttcgtccg
     6121 ctgctcggtt atctgcccaa gtgatcattc gagataacgg tgttttctct tcatccaaca
     6181 atatcaggcc atgcatcgca gaggagaagg agacaaattg aatgattgtg tctgaaggca
     6241 actgtttaat tacttctttt ataacggtgc agacaccttg aaagatcaat tcctgatctt
     6301 gttctgccat cccttgtgtt tcttggatca aagggtagcg aaaataagcg gatgctgctt
     6361 cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt ggttccgata tctaatccga
     6421 ttgaaacgtt cattttttca cctcaaattt tatgtatgta caaaaattta gtttaagctt
     6481 gcgtatcttg gttttgaaaa gggggagatg gcgtgttact ttattttatc attggttgct
     6541 gtatcggatc atttttatgt ttaaccgccc agcggattcc gttaggtcac tctattattt
     6601 atcctagatc tcattgtgtc aaatgctgtc gttcgctttc ttggtatgaa ttgattccga
     6661 ttctctcgat catcgtccaa cgatttcgct gccgctattg caggtgtcgg ttgcccttct
     6721 actatttgtt ggcagaagcc ttatgtggtg gtctttttgc ctggttcttt actttttctt
     6781 ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc tttgctattt tcgttgatgg
     6841 atttatttta cttcatggtc cattctcaca cgctattctg ttcttgggca attttatgga
     6901 ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt gctgttaacg tttatcgtag
     6961 gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc tggcgatact ctgttgatgc
     7021 tttcttggag tggtggcttg tctctagaag agttgcttca gatcttgttt cttgctagtc
     7081 tgtttggaat atccgttttt tctgtttact ttatctgtca taaaaaaaag ttggaaaagc
     7141 tgcctttcat tccttttttg agcagtgcgt tgctgattgt ccttcatctt aggtattgaa
     7201 aaaaggttgt gacaaacgac ttgtcacaac ctctgatata tagtgttctc ttaccaaatc
     7261 cttgtgactt ggagctaggc gacaggttca caacctctcc actaaatggt gttcaatcag
     7321 ctgaccctca gtattagctc aaaatgctgg ttttacaacc tctgatatac ggtgttccat
     7381 aagtagcttt ttcggcttct tatttcttga cgccccaatg tcgacgaagg aaacctgcac
     7441 gtccagaacc ttctcgataa agattgtaat ggagcttgtt tttcttgtaa taatcctgat
     7501 ggtaatcttc tgcaggataa aattcgcttc ttggttcgat ttttgtcacg attggcttat
     7561 cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc tgcaatattt cgttcttctt
     7621 catcattata gtagatcact ggacgataag aatcaccgcg atcagcgaac tgtcctaatg
     7681 cgtcagtcgg atcggtttgc tgccaataga tttccaccaa ctgatcataa gaaataactt
     7741 ctggatcata ttcgatctct actgcttctg tatgccctgt tgtgcctgtt gttacttgtt
     7801 cataagttgg atttggtaca tgcccgccag tataaccgga tgtcacagaa atgatccctg
     7861 gctgctcttc aaatggtttg accatacacc aaaagcatcc gcctgcgaaa actgcttttt
     7921 ttgtcatata aaatccccct tttttctcat cataccttga tttccaaaag gaggataacg
     7981 ttttgcttgt gacagaaaaa acggaaacta ttatatacgt gatacggctt ctgataaatg
     8041 ccaaaacgaa cgtacttgat caaaaacggt taaatcagga atcacatatt cagcagaagg
     8101 aagatttatg ttttcaccta ttcccaatac atgcatgtta ccagccaaag ctgcttgaca
     8161 accagcttct gaatcttcaa tgaccaagca tgcatttggc ggtacattca attgctgtgc
     8221 tcctttgaga aaaacttctg gatcaggttt tgcttttgat acttgcgtgc cgtcaataag
     8281 gacatcaaaa taacttgtca aattcgtttt ttctaaaatg aggcgtgcat ttttgcttgc
     8341 tgatcccaat ccgatcttga tgtttgtttt tttcaagtac tcaagaacag ctattgcacc
     8401 aggcaaaacg gatgtttcat ccattttttg aatcgcttga agatatagat tgtttttttg
     8461 ctcagcaaag gctgatttct ctttttctga gaatttctgt tccatttttc caaatgacag
     8521 caatcgctct agtgactcgg ttctggatat tcctttcagt tgctcgtttt ctttctcagt
     8581 gaatggaatg gacagctggt tagctaaaac cagccacgct tcgtaatgat aacgagctgt
     8641 gtctacaaga acgccatcta aatcgaatag tgctgctttg attttcatcg attacctcct
     8701 tgaaaatgaa cgacttgaag taaagatgcg atgtttttag ctgtgcgatg aagattatca
     8761 gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag gaaggatcgg aaaaacggcc
     8821 gaaatgccaa catctgctgc tttttcgctt cctttaccaa cacttccgca aatagctatc
     8881 acaggaacgc cctctggtac tcttctagca atcccaactg gcgcttttcc ttttagactt
     8941 tgtccatcta gacgtccttc gcctacgatt acgaggtctg cttgctgtac ccgtttatcg
     9001 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
     9061 aacagtcctg cacccattcc accaccagca ctactgcccg atgcctcgat tacttgaggg
     9121 gcaaatctca tataaaaatc atgcatggct tggtcagcca ctgctaattc attttctttc
     9181 aagccttttt gtggtccgaa aacaaaagaa gcgccttctt ttccgcataa aagattagta
     9241 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
     9301 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
     9361 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
     9421 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
     9481 actcctcgcg tggataacct aagtggctgt tgttggttta gtgggacatc tttcaatccg
     9541 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
     9601 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
     9661 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
     9721 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
     9781 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
     9841 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
     9901 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
     9961 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
    10021 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
    10081 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
    10141 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
    10201 gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt ttcatagtaa tgcaaattct
    10261 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
    10321 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
    10381 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
    10441 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
    10501 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
    10561 tataatgcgc cagatagttc gtatatgcat tattgtcgat atattctgtg tattcatctg
    10621 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
    10681 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
    10741 ttgcttggac atactcttga acggcataag caaggtctgc actgatatga tgttctgcgg
    10801 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
    10861 tctcttcctg accagtgtgt gcgctttccc atgggaaaag tgcaccttga tagtgataat
    10921 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
    10981 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
    11041 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
    11101 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
    11161 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
    11221 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
    11281 acgggtctgt ttgctgaaga gaggtagaga gcacgatgat cttctccagc gtaaaggacg
    11341 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
    11401 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
    11461 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
    11521 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
    11581 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
    11641 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
    11701 gctctcccat ttctaaatct agtgcccgct cgtatgcaag aactttcatc gtctcaagag
    11761 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
    11821 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
    11881 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
    11941 tctgactcgc atacttattg atatactcta aatcaaactg tttttcttct actttcataa
    12001 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tctggatgac
    12061 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
    12121 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
    12181 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
    12241 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
    12301 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
    12361 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
    12421 gtacgcccga acgcttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
    12481 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
    12541 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
    12601 aacatcaaga tgattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
    12661 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
    12721 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
    12781 ttcgaagtga aagcgattgg gtgtacagac actcacgata tcgggagaaa tctcattcag
    12841 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    12901 tcgctggctg actggatcaa ccacagcggc caattctaag acatctgatc ttttttgata
    12961 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    13021 ttatttctct ctcctttgct tatttactta ttgttattct ttctctattc tttctctaaa
    13081 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    13141 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    13201 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    13261 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    13321 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    13381 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    13441 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    13501 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    13561 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    13621 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    13681 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    13741 gtttctttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    13801 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    13861 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tcctcggact tgaacgccca
    13921 ttttgatact ttcttctggg tgctggtcta cataacgcat gtaagcttct gcgctttctg
    13981 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    14041 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    14101 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    14161 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    14221 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    14281 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    14341 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    14401 cgatggtagt agcacctgct tttttagcta attgaatcgc aatttgcccg atagcgccta
    14461 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttcccggata ccacctaaag
    14521 cgaattgagc aggatcgtaa catactgcat ttttccattg atccaaccga tcaagtttac
    14581 gtagtttata attatcaaca ccgtttgtaa tcagcgtttc acgaatgggt ccataagtgc
    14641 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    14701 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    14761 ttggcaagaa taggcgccat tcttctgaaa attcttcatc gataaatgga cttaatcctc
    14821 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    14881 cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    14941 caactaattt tttcatcttt tctttcctct ttcttttctt tttatccttt tacgccgcct
    15001 tcgactaaat cacctttaat aaatcgttca gataacgcat acataatgat gactggtaaa
    15061 gcggtcacca atgaagcggc catcattcgt ccccaaatgt agtctggtgt actgaataat
    15121 gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg acaggaaaat cgaagcaaat
    15181 aaataatcat tccacgaaac cataaagcaa taaacgaaga cagaaatgat tccagaaata
    15241 gccaatggta taatgatccg aataatgatc tggatccggc taagaccatc gatcattgct
    15301 gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt ttagcatgaa tatcgcagta
    15361 ggaagtgttt gaacgaccat cgtgataatc agtgctgtat tggtatcata caaacctaga
    15421 ccggaaatga ttttaaataa tggaacaacg atcaaaatac cggaaaacat ataaacggtg
    15481 taaaagctag cattgatttt cgagcgagct ttgaagcgta gttttgacaa agcgtatgcc
    15541 ccgctgatcc caatcactac tgcagttacg gaggctatca aggagatcac taaactattt
    15601 ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa tatcctgata atgttcaaaa
    15661 gtccattctt tcggaaaaat agtttgtgtc gttgcaattg cttcttgtga atccttgaat
    15721 gatgtcatca gcatgatcaa aaatggaaac aaattgacag ctaatagcaa caaaatcgtc
    15781 gcgtaaaata agattttcct gctcttttta tttttcattt caagtccacc ttctttcgtg
    15841 agagcaagac gaccgctgca ataatgatga acaatagaat cgatatagct gctgcttttc
    15901 caagatcatt gaacgcaaag gctgtctgat acaaataaac gcctaagata ttgactttat
    15961 tcgtcagtag atagacatct gtaaacatat agaacatcca gatagatcgt aaaacaatca
    16021 cagttgctag tactggtttg attgccggca gtgtcacgat cttgaacttc tgccaagcat
    16081 ttgcaccgtc catttcagct gcttcataaa gcgttttgtc gactgtttgc aaaatagcca
    16141 aaaatgaaat aaacgcatac ggatagtatc tccagatagc aaacaaaacg accataaaga
    16201 agctagcaac tggctggtcg aaccacagcg gtgcttcgtt gaaaagctgc aacctatcta
    16261 ctaacagatc attgacgatt ccataactat tattgaacat atatttccaa gcaaaaatca
    16321 aagaaataga tggcgtaaca taacttaata aaatcagtga acgcaccgtt ttcctaaatc
    16381 tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa agctgtactg cctgctacaa
    16441 ctaagaatgt gtaagcaact gttaaaccta aagaacgata aaattcacta tcacttaaaa
    16501 tttcaagata attgcttaat ccgataaaaa cggcgtctga gttaggattc agcggcatat
    16561 cgaaaaaact gatctgaata ttggaaagca ttggaatcag cactaaaaca gctaataaaa
    16621 gcatgcttgg tgctaaaagt cccatggcta attttaagtc agaatgtttc cttggacgat
    16681 tcattgaaac ctccccctga taatctgcca atagctatct acttttttcg aacaccattg
    16741 gcagaacttc ttgttatttc gtattttttt gtgcgtcagc taaagcttga tcgacatctt
    16801 cgtttccgac agttacttgg ttcactgctt ttccgatcac acctgagctt gtgatatctc
    16861 ccattttcgt gaaattcttt tccccgacta gtccaaagac ttgtacttca tcaaaagcac
    16921 tagcaatctc agatggcagc tcgccaaaag acttgatgac ttcattttct ttgtaaccat
    16981 ccagttcgac tacttgttta ttcactggtt gagcaccacc aggagacatc aagacccact
    17041 tttccatgtt tttcggttga gataagaaag ctgtgaatgc ttcagcagcc tctttttgtt
    17101 tctcgtctag accagaagaa atcgtcaatc cagatactgt gccatagaca gcttgatctt
    17161 tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc cgcttcataa acagaaggca
    17221 aaatgtaagt tgaatagatt gccattggtg ctgttccatt catgaaagca tctttgattt
    17281 ctgtcacatc attagagcct ggcatcgtgt attgggataa gttttgataa aacgacaatg
    17341 cttctctcat cttttccgta tcgatcgtta cctcgccttc atcatccaaa acatttgctc
    17401 catttgacaa agcaaattga gagaacgctt gctcactcat tgttccttca gcagtaggca
    17461 tagcaattcc atattgttta ttctctttat ctgtgaaatg ttgagcaatt tttaaaatat
    17521 catcccaatt ttctggttct gaaaaaccag cttctgataa tttttctttg tcataccaaa
    17581 taccttgaac ccagccgcta attggtgcag caatatagct ttttccatct tctgaacgaa
    17641 caaggttttt ggctccgtca taataattat cttctccagc ttcctcgata acgttttgga
    17701 ctgccgtctg atcaatcagt tcatctttat ccatcacttt agcaaaatcc tgactgactt
    17761 ccattacttc tggtaattta ccggaacgag ctaacgtaac gatttttgta ttgaacgctg
    17821 attcttctac cggcacttgc ttgattttga tgtctggatt ttctttttca aaatcagcaa
    17881 ccagttcatt gatcacactt aatcgttcct gttcgacaga agagtgcatg aattgaatcg
    17941 ttgtctgttg tgattcgtta gagctttgac tttcaccaca agcagtaaga agaaatccag
    18001 tagctagcag acaggtagta acaataattt ttttcatttt tttccacctc ttattttatt
    18061 attttcagcc acatatattc atacggctgg aatatcaact ttcgttcttg actgcaatgg
    18121 ataatttgtc cagaaaacag gtctaggtaa tctccttttg gtaaaagata acctgctgat
    18181 tgattggaaa aattatggat aactaagact ttctcttcct tcgcttcgcg aataaaactg
    18241 ataaaagaat ctgctgagtc cagtaagtaa atcaaactat tcggatggaa ggctttttct
    18301 ttttttcgaa tagatagcat ctgggtcaat tcaccatata ctgctgttct taatggatct
    18361 gtctgcaact ctttctcaat atctgctaac aaaaattttt gccgattgat ttttcgattc
    18421 tctcctgttt tttctacgcc tttgtaatca tttcgacttc ccagcacact ttgaatataa
    18481 attgccggca cgcctggtaa cgttaccaaa aatgaatgag cagctaaaaa gcgtttgctt
    18541 ctccattccg tcgtatctgt tggagaactt aacgcatcta gatacgtagc gtttatctca
    18601 tatggactgg tcgttccatc tgggtttttc ttgtagttta ctcgggcacc ctctttcttc
    18661 agctgttcca ctaattcaag gatcgttttt tccggcagaa tacctcgtac cggattcaat
    18721 ccgataccgt catgggaggc taaaaaatta aaaaaagttg tttttttcga tgcgaaatcg
    18781 atggttttta accattcttt caacttactt gtattacccg aacgaatcgc ttgaagggtc
    18841 aaaggtggta gcgaaaactg atagaccatc tgtgcttcat tctcgccatt cccaaaataa
    18901 ctgatattat ctttgtgtgg cacatttgtc tcagtgatca ataccgttcc tggagctgct
    18961 tcatcagcga ttgcacggaa taattggatg attttatgcg tttctggcag gtgtatacaa
    19021 gaagttccta gttctttcca taaaaatccc acagcgtcca agcgaataaa tgaagcgcct
    19081 ttttctaagt aaaacaaaag aatatcgatc attttcaata aaacttctgg atttttaaaa
    19141 ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt gtttttcttt cccgtttttg
    19201 tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag tcacgctgct tgtatctgta
    19261 tccagtggca aatcaataaa aaaatctttg tacgtatcat tcaagtttaa atattcctga
    19321 aaccaagtac tttcggcaga catatgattg cagacaaagt cgaacattaa ccgtgtttcg
    19381 cttctcattt cttctatatc ttcccatgtg cccaaacggt cgttgattgc ctgataattt
    19441 acaacggaga aaccatcatc agatgtatat gggaaaaatg gcaagaaatg tacaactcta
    19501 aatgtatctg ccaaatactt ttgataaaat ttcttaaatg tacgcaaagt tggttgctgc
    19561 tcttcaaaaa attgatcccc ataagtaatc aagaaaatat cttcttcgtc ccaatgcagt
    19621 ttgcctgcct ggcctttctt ctgctgataa acactgactt tttgttcaat catagaggcg
    19681 gttttctcag acaaatctga gtcgcgataa atcgcttgta aaagttttgt atacatcgga
    19741 ttcccctttc ttttttggga gcgttcccaa cgatttgatc atattatgga aaacgcttac
    19801 tgtcaatagc atttttttaa ataattttga tatacacaaa aatacaaata agaaagctta
    19861 tgtatcaata attaatagct tcttaaaaaa atatggtctc tcatgatcat gcaagctatt
    19921 cctaaatttt caaaatcata gacaaaaaag aatgtctatt gtactatgga attattctaa
    19981 aacgctccca aaaaggaggt gcatataaaa ttgaaaccta ctatttatga cattgcgaaa
    20041 aaagctaatg tctcaaaatc aactgtctcc agagtattaa ataaccagcc aaatatctct
    20101 gataaagcaa aagcaagtgt acttcaagca atcaaagaat tgaattatga accgagcaaa
    20161 attgcaagag gactgtcagg aaatggtttt gacgcgattc tagcattatc tcatcgtact
    20221 tctcatacga cctatggcaa tccttttttt tcagatgtta ttcaatccat ttctgccgtt
    20281 tctgaacaaa ataacttcga cttgattcta caaacggcaa aaacaccaga agaagagcta
    20341 gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag gaattattat tttaagctct
    20401 acgatggatg aaacacttct ttttgaattg gatcaataca atattcctat tgtggtaatc
    20461 ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg acacggataa tttccaggat
    20521 agttacgatt tggtggaaac actgatcaag aatggacacc gtcatatcgg ctgtctccat
    20581 gctccgacag aagtttatgt atccaatgat cgtctcaatg gttaccgtca atgcttattt
    20641 gatcaccacc tagatatccg taatgaatgg attatagacg gcggctttcg cttagaagat
    20701 agcatggcag caatgaatga tttaatgaag ctacgagaaa gaccaactgc gattttttct
    20761 accgatgcat taaaatcatt gagtatttac aaagtggcag aacaatctgg aaagcagata
    20821 cctgatgatc tttcgatcgc aggattcagt gatcccttat tgtcctccct attttcgcca
    20881 cagttgactc ggatagacat tccgacaaat cagttaggaa tcaaagccac agaactttta
    20941 ttccaactaa tccaccacca ataccctgaa gaaaaaagaa tcattctttc aaccgagatt
    21001 actctcacag attcgatcca acaacaagaa atgtagaaca gaattataaa agaacagaaa
    21061 cactgaggat aagtcagtta ctctgttctt ttttcaatca ctcatccctc gttaccccct
    21121 cccggtattt tagcgaattt ttcttatttt ccatctgttt tagatagctg tggataacta
    21181 taatgtttgt gttaaactat tttttccaca gggaagaaaa aactattttt aaccacgttg
    21241 tgtataagtt tttatagttc gtttttttaa acacatttac ccttatttca atccatgtta
    21301 tttggggata cttatctcta aaacataaat agaataacag acatgtctac tggttttgtt
    21361 ttattcgagg aattattcaa taatagctag caaaatatta aaaataaccg ctctatcttc
    21421 ccatcaattt attttgcatt caaaaaatga tctatcttta cttttgttga ttgacttctc
    21481 ttggaagatg atcgttccga taccttaatt ggatacgaac cgatgttgtt aagatccttt
    21541 cccacttttc ttctagttag acaaattatt ttagacaaac caaaaaagag gttgtgacaa
    21601 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
    21661 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
    21721 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
    21781 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
    21841 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
    21901 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
    21961 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
    22021 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
    22081 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
    22141 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
    22201 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
    22261 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
    22321 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
    22381 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
    22441 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
    22501 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
    22561 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
    22621 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
    22681 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
    22741 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
    22801 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
    22861 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
    22921 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
    22981 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
    23041 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
    23101 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
    23161 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
    23221 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
    23281 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
    23341 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt tgaatcgttt
    23401 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
    23461 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
    23521 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
    23581 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
    23641 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
    23701 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
    23761 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
    23821 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
    23881 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
    23941 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
    24001 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
    24061 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
    24121 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
    24181 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
    24241 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
    24301 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
    24361 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
    24421 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
    24481 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
    24541 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
    24601 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
    24661 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
    24721 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
    24781 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
    24841 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
    24901 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
    24961 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
    25021 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
    25081 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
    25141 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
    25201 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
    25261 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
    25321 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
    25381 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
    25441 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
    25501 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
    25561 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
    25621 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
    25681 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
    25741 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
    25801 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
    25861 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
    25921 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
    25981 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
    26041 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
    26101 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
    26161 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
    26221 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
    26281 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
    26341 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
    26401 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
    26461 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
    26521 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
    26581 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
    26641 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
    26701 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
    26761 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
    26821 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
    26881 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac cgtcatgttt
    26941 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
    27001 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
    27061 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
    27121 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
    27181 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
    27241 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
    27301 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
    27361 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
    27421 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
    27481 acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca attcgccaag
    27541 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
    27601 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
    27661 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
    27721 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
    27781 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
    27841 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
    27901 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
    27961 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
    28021 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
    28081 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
    28141 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
    28201 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
    28261 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
    28321 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
    28381 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
    28441 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
    28501 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
    28561 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
    28621 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
    28681 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
    28741 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
    28801 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
    28861 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
    28921 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
    28981 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
    29041 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
    29101 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
    29161 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
    29221 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
    29281 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
    29341 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
    29401 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
    29461 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
    29521 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
    29581 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
    29641 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
    29701 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
    29761 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
    29821 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
    29881 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
    29941 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
    30001 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
    30061 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
    30121 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
    30181 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
    30241 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
    30301 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
    30361 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
    30421 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
    30481 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
    30541 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
    30601 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
    30661 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
    30721 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
    30781 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
    30841 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
    30901 gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
    30961 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
    31021 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
    31081 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
    31141 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
    31201 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
    31261 atttctaatg gatgcattgc tctttctggc tccttacttg cgcaaaacaa cggctttgct
    31321 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
    31381 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
    31441 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
    31501 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
    31561 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    31621 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    31681 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    31741 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    31801 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    31861 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    31921 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    31981 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    32041 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    32101 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    32161 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    32221 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    32281 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    32341 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    32401 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    32461 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    32521 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    32581 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    32641 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    32701 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    32761 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg ttgacttctg
    32821 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    32881 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    32941 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    33001 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    33061 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    33121 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    33181 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    33241 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    33301 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    33361 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    33421 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    33481 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    33541 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    33601 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    33661 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    33721 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    33781 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    33841 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    33901 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    33961 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    34021 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    34081 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    34141 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    34201 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    34261 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    34321 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    34381 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    34441 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    34501 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    34561 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    34621 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    34681 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    34741 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    34801 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    34861 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    34921 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    34981 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    35041 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    35101 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    35161 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    35221 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    35281 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    35341 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    35401 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    35461 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    35521 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    35581 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    35641 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    35701 tgatagctca gattcatca
//
LOCUS       DAFEIE010000027        35018 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFEIE010000027
VERSION     DAFEIE010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.027"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(55..2652)
                     /gene="adhE"
                     /locus_tag="LP345_001427"
                     /gene_synonym="adhC"
     CDS             complement(55..2652)
                     /gene="adhE"
                     /locus_tag="LP345_001427"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBL1760213.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(2957..3337)
                     /gene="yajC"
                     /locus_tag="LP345_001428"
     CDS             complement(2957..3337)
                     /gene="yajC"
                     /locus_tag="LP345_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBL1760214.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(3434..4579)
                     /gene="tgt"
                     /locus_tag="LP345_001429"
     CDS             complement(3434..4579)
                     /gene="tgt"
                     /locus_tag="LP345_001429"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBL1760215.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            4797..5495
                     /locus_tag="LP345_001430"
     CDS             4797..5495
                     /locus_tag="LP345_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL1760216.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(5663..8302)
                     /locus_tag="LP345_001431"
     CDS             complement(5663..8302)
                     /locus_tag="LP345_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1760217.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(8921..9952)
                     /gene="queA"
                     /locus_tag="LP345_001432"
     CDS             complement(8921..9952)
                     /gene="queA"
                     /locus_tag="LP345_001432"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBL1760218.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            10145..11320
                     /locus_tag="LP345_001433"
     CDS             10145..11320
                     /locus_tag="LP345_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1760219.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            11324..11965
                     /locus_tag="LP345_001434"
     CDS             11324..11965
                     /locus_tag="LP345_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760220.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            11962..12879
                     /locus_tag="LP345_001435"
     CDS             11962..12879
                     /locus_tag="LP345_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1760221.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            12876..13547
                     /locus_tag="LP345_001436"
     CDS             12876..13547
                     /locus_tag="LP345_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760222.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(14088..14576)
                     /locus_tag="LP345_001437"
     CDS             complement(14088..14576)
                     /locus_tag="LP345_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBL1760223.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(14777..15043)
                     /locus_tag="LP345_001438"
     CDS             complement(14777..15043)
                     /locus_tag="LP345_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL1760224.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(15043..15306)
                     /locus_tag="LP345_001439"
     CDS             complement(15043..15306)
                     /locus_tag="LP345_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1760225.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            15782..15967
                     /locus_tag="LP345_001440"
     CDS             15782..15967
                     /locus_tag="LP345_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1760226.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(16109..17932)
                     /locus_tag="LP345_001441"
     CDS             complement(16109..17932)
                     /locus_tag="LP345_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBL1760227.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(18530..21235)
                     /locus_tag="LP345_001442"
     CDS             complement(18530..21235)
                     /locus_tag="LP345_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBL1760228.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(21541..22488)
                     /locus_tag="LP345_001443"
     CDS             complement(21541..22488)
                     /locus_tag="LP345_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBL1760229.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            22678..22947
                     /gene="rpsN"
                     /locus_tag="LP345_001444"
     CDS             22678..22947
                     /gene="rpsN"
                     /locus_tag="LP345_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL1760230.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(23123..23485)
                     /locus_tag="LP345_001445"
     CDS             complement(23123..23485)
                     /locus_tag="LP345_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1760231.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(23496..24617)
                     /locus_tag="LP345_001446"
     CDS             complement(23496..24617)
                     /locus_tag="LP345_001446"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBL1760232.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(24633..24983)
                     /locus_tag="LP345_001447"
     CDS             complement(24633..24983)
                     /locus_tag="LP345_001447"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBL1760233.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(25113..26624)
                     /locus_tag="LP345_001448"
     CDS             complement(25113..26624)
                     /locus_tag="LP345_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1760234.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(26946..28298)
                     /locus_tag="LP345_001449"
     CDS             complement(26946..28298)
                     /locus_tag="LP345_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBL1760235.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(28451..29527)
                     /locus_tag="LP345_001450"
     CDS             complement(28451..29527)
                     /locus_tag="LP345_001450"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBL1760236.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFNMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            29723..31468
                     /locus_tag="LP345_001451"
     CDS             29723..31468
                     /locus_tag="LP345_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBL1760237.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(31748..32185)
                     /locus_tag="LP345_001452"
     CDS             complement(31748..32185)
                     /locus_tag="LP345_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBL1760238.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(32169..33542)
                     /locus_tag="LP345_001453"
     CDS             complement(32169..33542)
                     /locus_tag="LP345_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760239.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(33864..34352)
                     /locus_tag="LP345_001454"
     CDS             complement(33864..34352)
                     /locus_tag="LP345_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1760240.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(34374..34976)
                     /locus_tag="LP345_001455"
     CDS             complement(34374..34976)
                     /locus_tag="LP345_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL1760241.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         9919 a         7475 c         6466 g        11158 t
ORIGIN      
        1 tttccaagtt ctttttcatc tattttctta tcttttttct acgctttctt ttgcttatcc
       61 gttgtaagca tcaatgatga tctgtttcaa ttcagagatc aatggttctt tcggattagc
      121 tgtcgtacat tggtcttcgt aagctaattc agccatacgg tctacggttg tatctagtgt
      181 ttcttgtgtg actccttgag cttttagact catgttgatg ccgacagatt ttcctaattc
      241 ataaacagcc gttgctaaag cttcgactaa ttcctctgtt gtttcgcctt tcagacctaa
      301 gaattttgcg atatctgcgt aatctgtatc tgcacggaaa tagtcatatt tagggaacat
      361 cgcatgtttt tgtggatctt ttgcattata gcggataata tgcggtaaaa gaatcgcatt
      421 tgtccgtcca tgagggatcc cgtattcccc gccgatttta tgtgcgactg agtgacaaat
      481 acctaggaat gcgttagcaa acgccatacc agccattgta gaagcgttgt gcattttttc
      541 acgtgattcc atatcaggtg tttttactga tttttctaaa tagtcaaaga ctaacttgat
      601 tgcttgtagg ctcaatccac gtgtataatc tgaagccatg actgaaacat aggattcgat
      661 tgcatgtgtt aacacatcca tcccggtatc tgctgtgaca gatgctggaa ctgacatgac
      721 gaattgagga tcgacgattg cgacatctgg cgtcaatgca taatctgcta acggatattt
      781 cacatgtgtt tcactgtcag tgatgaccgc aaatggcgtt acttcagaac cagtccctga
      841 tgttgtcggg atacatacga attgtgtttt ttctggtttg tcgatcttat atgtccgttt
      901 acggatatcc aagaattttt gttttgcacc aaagaaagat gtgtctgggt gttcatagaa
      961 catccacatt cccttagctg cgtccattgc agaaccgcct ccaagagcga ttactgtatc
     1021 tggcttgaag tctgccatca gtttcgttcc tgcgtatacg gtatttgtcg atgggttcgg
     1081 ttcaacatct gagaagactt cgatcttcac atcattttta cgtcgtgcca atacttcacg
     1141 aactgtatcg cagtaaccga attggaccat accagggtca caaacgatca tgacacgttc
     1201 aacgttttcc attttctcta agtacaatag agagttcttt tcaaagaaga tttttggcgg
     1261 taatttgaac cattgcatgt tatttctccg tttcgctaca gttttgacat tgattaagtt
     1321 tacagcagag acgttacgag aaacagagtt cttaccataa gaaccgcatc ccaaagtcaa
     1381 tgacggaatc atttcgttat agatatcacc gatgccgcct tctgcagatg gtgtattcac
     1441 taaaatacga caagctttca ttcgaagacc gaatttgaca tgcaactctt cgttttctga
     1501 atggataact gctgtatgtc ctaatcctcc aagattcaac ataccttcac acaaatcaaa
     1561 cgcatggtcc gtgttgttag ctttgatcat ggcaagaact ggagaaagtt tttctcttga
     1621 tagcggataa tctgggccta cgccttccaa ttcagcaatc agcattttcg ttccttttgg
     1681 tacactgatt cctgccaatt ttgcgatttc catcgcagaa tgtccaacga ttgatggatt
     1741 gaccgcatat tttccttcgt tcatcactgc atcttctaat ttttgcaatt catctggttt
     1801 tacgatataa acttggtgtg cttggaattc tgcttttact gctgcataga tttctttatc
     1861 cacgatcaca gcttgttcag aagcacaaat cattccatta tcaaatgttt tcgaaacgat
     1921 caaatcgttc actgcacgtt taatttttgc tgttttttca atataagctg gtacgttacc
     1981 tggacctaca cctaaagctg gttttcctgt agagtaagca gacttgacca ttccagctcc
     2041 acctgtcgct aagacgatcg cgatacctgg atggttcatt agcatagaag tcgcttcgat
     2101 cgaaggatgt tcgatccatt ggatacaatt ttcaggagct ccggcagcga tagcagcatc
     2161 acgtaccact cgtgctgctt ctgcagaaga tttttgggca cttggatgga aagcaaaaac
     2221 gattggattt cttgttttca acgcgatcat tgatttgaaa atcgttgtgg aagtcggatt
     2281 cgttgttgga gttactccgc aaaccacacc gactggttca gcaatttcaa tcaacccttt
     2341 ttggacatct tcattgatca caccaactgt tttatcatgt ttgatattat gccaaatata
     2401 ttcggacgca tacatatttt tgattgcttt atcttcgtaa acaccgcggc ctgtttcctc
     2461 tacagccatc ttcgctaatg gcatatgttg atccaaagct gccattgcca tttcatgcac
     2521 gatatggtct actttttctt gatcaaagct ttccatttct ttcaatgctg catttgcttt
     2581 ttctgccaaa tcatcaatca ttgcttgtac gtcaattgtc ttcgtttttt ctttttctat
     2641 tactttagcc atcattatcc tcctaatggg tcatggttat ttgttaaata attcacatgt
     2701 atatcataca atatttattt ttctatgtaa acactttttt gtgatttttt tcacagttat
     2761 ttttaaatat aaaattgctt tatttacagg tgtttgtata gaaaaatata taaagttatt
     2821 tattattatt tatatgacac acccgattat tcaatattga gcaatatatc ccatgctctt
     2881 atctctttct tttttgaata aaaaatgagg taggacatct ttctgcccta cctcgtcttt
     2941 aaataagctt tgatacttat ttttcttcct tctcttctgt ctcttccagc gtttctgttg
     3001 tttcagtttt tacttcaact gtctcagctg gttcttctgt tgtttcaaca gtagtcgttg
     3061 catcatttgt tacgacagtc cctggtttga ccgttttgat tgctgcacga tcgtactcaa
     3121 ggaagatccc ttcgcagtct aaaacaactg tccgtttgtc attgtcgatt tctgaaacaa
     3181 ctccatgtaa tccgccgatc gttacgactg aatcacctgg tttcatgcta tctaacaagt
     3241 tttgacgttc ttgctgttgt ttcttttgcg aacgtgacat aaaaaaccac attgctaata
     3301 gcgcgataaa catcacaagc attggtaatg ttcccatttt tttcacctca ctaattctgt
     3361 atctacaaaa aacactttag cagaaaaatg ctgataacac tagtttttta cttaattttt
     3421 aaaagatttt cctttagaag ctttttgcgt tttctttatt gaacccgtat tcttcaaaaa
     3481 aggcttctct aaattcaagc aaattatcat ccatgattgc ttgacgtact tgtttcatta
     3541 gattcaacaa gaagtataaa ttgtggtaag aagtcaaacg aatcccaaat gtttcatcac
     3601 atttgatcaa atggcggata taggcacgtg tatagttttt acatgtataa caatcacatt
     3661 tctcatcaat tggacggaaa tcatgggcat atttcgcatt tttcactact agacggcctt
     3721 gagaagtcat acatgtgcca tttcgagcga ttcgagtagg caagacacag tcaaacatgt
     3781 ctactccacg gataacacca tcgatcaatg aatcagcagc accgacaccc atcaagtaac
     3841 gtggtttgtt ttcggggatc aacggtgtag tgaattctaa tacacgattc atttctgatt
     3901 taggttcccc gacagataac ccgccgattg agtaaccagg gaaatccatc ccgactagat
     3961 ctttcgcgct ttgacgacga agatcttcaa accctgctcc ttggatgatt ccaaataatc
     4021 cttgacggtc tggattagca tgagctttca atcctcgttc tgcccatcga gacgtacgtt
     4081 ctactgattt tttcacgtag tcgtaacttt catcgaatgg tggacattcg tcaaaactca
     4141 tcatgatatc agagcccaat ttattttgga tgttgattgc tttttctggt gataaaaaca
     4201 tacgcgaacc gttcaagtga tttttgaaat gcacgccttc ttcttcgata ttccgcatat
     4261 cacttaatga aaaaacttga aagccgcctg aatctgttaa aatcggttga tcccagttca
     4321 taaatttatg cagtccgcca gcttcttcta ctaagtcttc accagggcgt agccataaat
     4381 gatatgtatt acttaaaata acgccagcac ccatttcttt caactcttct ggggacattg
     4441 tttttactgt agctaatgtt cctactggca tgaacattgg tgtggggaaa gttccgtgtg
     4501 gcgtgatcaa ttcccctaaa cgcgcgccag tatgtttttc tttcttgatt aaacgatagc
     4561 gaatggcagg ttgcgtcatt catttcccta ctttctatat aaaatatctt gacaactccc
     4621 accatcataa tcgtttcaag tgctttttgc aagttccctc ggcttccttc tactttattt
     4681 aatattcttt tttttatcct ttttttatga ataacaaaaa aaagaaaaac attatgacag
     4741 aaatattttt tgatacatgg tatattggtg ttattaaaga aaaggaggga aaaatcatgc
     4801 aatcttctgc agaattaaaa cgccaagcaa aagagagtct aaaaggacgt tggggacaag
     4861 ctgttttact aaatctaatc cctacattga ttggtattgc tactattctt cttattatga
     4921 ttcctattat cttgtttgcc accaccatat atgatggatc agcgagcgtc tcagaagcga
     4981 caacttcagg aggcggtagt tcaggaggcg gtggcggaat tatttccagc atcattagcg
     5041 ctttgttcat gagcggtatt tcttggactt atcttgatat tttacgtgga caaaaagatc
     5101 agatcgaacc attcaaagat gcatttcgtg gattcaaagg tttgtttatc ggcggagtga
     5161 tcagcttagc tgtgctgatc tcgatcttta caacattatg gggtttgcta ttagttattc
     5221 ctggaatcat taaaagctat tcttattctc aaagctattt tatttactac gatatcgtcc
     5281 aagaaacagg acaaacacct aaagtactgg atacgatcac tgcaagtcga aaattgatgg
     5341 atggttataa aggacaactt ttctggttag atctttcatt tatcggctgg catatcttag
     5401 cattagcaac tgctggtatt ggttatctat ggctcagccc atacatttct gcaacaaaag
     5461 cagcatttta tgaacaattg ccaaaagata tttaaaagag agtgtgactt gtgaccgagg
     5521 gggtggcagg agaacaccgt ttatcgagag gcagtaaaag aaacattcag cccattagca
     5581 aaaaggaggt gtgacaacat tcatgtcaca cctccttttt gtatagttcc agtaaaaaga
     5641 aaatcaactt agaaacagtt aatcattcct cttcttctgc ttccggtaat cgatggaact
     5701 tgatcagttc attcaccgcg attggtacga tagataaaat ccctaccaag aaccagtgat
     5761 tcaaactgat gtgtactagg ccgaatagtt cttgcgtaaa tggcagcaaa gcaacagccg
     5821 ttgtaatagc taatgccagt aacgccattt ctaccaaagc tttattggtc gctaaattga
     5881 ctttgaagat cgattggctg ctgcgtacat tgaacacatg cagaatcgat gaataagcta
     5941 agatcaagaa tgcaacagtt tgaccgacat gctgacttgc gtctacccat gggctgatag
     6001 tatcgacata actacctaaa taataaccaa acaaggttac gatggtgaag acccctgcat
     6061 ttatggcaat tttttgcaat aaacctcgag caaagatccc ttcatttttc ggaatgggtg
     6121 gctgatccat gatgccgtgt tccgctggct ctcttcctaa agcaaatcct ggaagtccat
     6181 cagcaactac attgacaaac agtagttgca cagctgtaaa tggtgctccc catcctaaca
     6241 gcatcgcaat caaaacaata aagatctccg aaatattaca gcttagcaaa aagttgatag
     6301 ctttacgaat attctgataa accgaacgtc cttgactgac agcgtctacg atcgtcgcaa
     6361 agttgtcatc cgtcaaaatc atatctgcgg cactttgcgc cacatctgtt cctgtgatcc
     6421 ccatggcaca cccaacgtta cttgctttca acgctggtgc atcattcaca ccatccccag
     6481 tcatcgctac gactgcaccc gtacgttgcc aagatttgac gatccggatc ttgtcttctg
     6541 gcgttacccg agcatagaca gagagagctt tgacacgcgc atctaattct tcgtctgata
     6601 attgatgcag ttctgatcct gaaagtgctt ctgacggatc attcaagata cctaattctt
     6661 tcgctatggc actggcagtc accacatgat ctccagtgat catgactgtt ttgatgccag
     6721 cctttttcgc tcgcttgatt gctcctttac tttctggacg tggtggatcg atcattccga
     6781 tcagaccaat caaacgtaag tctttttcca gtgcttcaga agaaatatct tgcggttctt
     6841 cgtcataagt agcataacca acagcaatca ctctcagtgc ccgtttacca aagcgatcat
     6901 taacgatcgc cgcttgttct acatcgcctg aactaaagcg cggagcaaga acatcgaatg
     6961 ctcctttggt gattgagatg tatttttcgc ccatttggtg aactgttgtc atcatttttc
     7021 gttcagaatc aaaaggaagc tcgtttactc gtggatattt ttcttctaat tctgcctttg
     7081 tatgataatt ctcttcaaca gcccttacga tggctacttc tgttggatta cctttgataa
     7141 caaggtcgtc atcttcttgc tcgaccgtca catctgtaca tagtgcagcc attttcaata
     7201 tttccatcgc gctgttcgtc attgaatctt cgatattcgt tacttcatct tctttgctcc
     7261 atacccggcg gacgcgcatt tcattttgtg tcagcgttcc tgttttgtct gagcagataa
     7321 cattagcggt tcctagcgtt tcaactgctg gcaactgtcg gatgatcgca tgtttcctcg
     7381 ccatcttctg cacaccgtat gcaagtgtca acgtaacaat aacagtcaag gtttccggta
     7441 cagctgcaac agccaaggaa atcgaagtca tgaacatctc aaggagtggt tctccttgca
     7501 gttcaccaat cacaaatact aaagccgcag ccgctaaagc gatcatactg attcgtttgc
     7561 ctagctgatt caatcggacc tgtaaaggtg ttttttgcat agtattttcg ttcaaaagat
     7621 ccgcgatctt acccatttct gtagccatgc caatggcagt gacgatcgct ttcccacgac
     7681 ctgcagcaac cgtacatcct ttaaatacca tattaagttg gtcacctaat gactcatctt
     7741 cttcagcaat aaatgctgca tctttttcaa ctgcttcact ttctccagtc aacgccgatt
     7801 cttctacacg taattgtgat gcttcgatca aacgggcatc ggcagaaata gcatcaccgg
     7861 actctaaaac aagaatatca cccactacca gttgctctga ctcaacagtg gtcactttgc
     7921 cgtctcgtat gacagttgcc gtttgtttat tcatatcttg caaggattcc agtgcttttt
     7981 ctgcgtttcc ttcttggaca atcgccaata ccgagttgat cacaacgata gcgatgatca
     8041 gcagtccttc aaataaatcc ccatgttctg tagcaaatgc ggtataaaag gaaatcaccg
     8101 ctgctacaag aaggatgatc gttgtaaaat cggacaagct tcgaaagaat tttttgatca
     8161 tcgattcttt cggcgcctca tcgaatttat tcaatccctg cttttttcgc cgttcatcca
     8221 cttcttgtga agacaaccca gtatctggat ctgcttctgt taccttcttt acttcttcta
     8281 ttgtctgctt gtattcttcc atcctattcc tcctttaaaa tcttcgtaca aaaaaaggta
     8341 cttattttac tataacatcc tttttttatt tacttcaaat aaagggctta tcgattattt
     8401 gttaagaaag cgtaaaattt aaagtgctta tatttgcaaa cgctaccaaa ggatgctatt
     8461 atatagatgt aaggaaggag gataccatca aatagacaga agaatttctc gatagaacag
     8521 tgtaagcaaa caaagttgtt agaagtacag gtttcaccca gacatgcgtg tagagtacaa
     8581 acctataaat agtgaatgcg tatggatgtt tggatcacga agtatccgaa acaagaagta
     8641 atgcgatacg taacaattga ataacgtaaa cgtctgaaaa ttgaatagga acaagagatg
     8701 tttcaaatgt tgaagatgta acgaaaacaa aatttttgtt taacatgaag aaattcaaca
     8761 ccgtgctttg catgtatgat ggaaagttac aatcatttct gtttatttga atccttccga
     8821 ggtacaagaa agccgagctt atcgagagct cggctttttc tttgtcataa aatctttgta
     8881 aagctttttt gttattcaaa actagcggct tttcataacc ttatttcacg aacatcgcat
     8941 ctccaaaact aaagaaacga tagcgctctt caatcgcatg ctggtaagca gataaagtca
     9001 attctcttcc tgcaaaggca ctaactaaca tgactaaagt cgattttggc aaatggaaat
     9061 tagttgagaa agcttctacc actttgaatt catagccagg cgtaatgaaa atatcagtcc
     9121 atccgctgtc tgctttgatt tctccattaa atttcgttcc aatcgtttct aatgttcgaa
     9181 ttgaagttgt tccgacagcc acgattttcc cgccattttt acgtacttgg ttcaatcgct
     9241 cagccgcttc ttccgtcaaa cggtagaatt cactatgcat atggtgttct tcaattttat
     9301 ctacgctgac aggtcggaat gtacctaacc ctacatgtag tgtcagatag actaattcaa
     9361 caccctttgc ttcgatctca tcaagtaatt ctttcgtaaa atgcaatcca gctgttggcg
     9421 ctgcagcaga accattttct ttcgcataga cagtttgata gcgatctggg tcttccagac
     9481 gttctttgat atatggaggc aatggcattt ctcccaatga ttcaagaatc tctagaaaaa
     9541 ttccttcata ctcaaagtca atgatccgtc cgccgtgttc caattcttct ttcactactg
     9601 cttgcaatct gccatcacca aaagagattc ttgtcccaac tttggcacgt ttcgcaggtt
     9661 tgatcaatgt ctcccacgta tctccttgtg tattcgttag aagaaggact tctaaatgcg
     9721 caccagtatc tggtttttct ccatataaac gagcaggcag aactcgtgta ttattcataa
     9781 ctagcgcatc accaggctgt aactcttcaa tgatttcatg gaaatgttta tcttccatct
     9841 ctccagtttt ccgatccaaa acaagtaaac gagaatgatc gcggtctttt aatggtgttt
     9901 gtgcgattaa ttcttccggc aagtcaaaat caaaatcttc tgttgttaac atatcgtcac
     9961 tcactttcta tcatgtgctt catcattcta tcatgttttt cgttctgttg gcaaaatcag
    10021 cactttttca cttctatttt ttgttttcct aaataaaaaa actaccctat ttgtattttt
    10081 tcattgtttt aggcatacta gtaatagata gttcttcatt gaaaatagaa aaagaggtgg
    10141 caccatgatt gaatttcaaa atgtgtcaaa aatttataaa ggtggaaaag tcgctgtaga
    10201 ggacgtcaat ctttcatttg aaaagggtga gttcatttgt tttatcggta cgagcggaag
    10261 cggaaaaacg acgacgatgc ggatgatcaa ccgaatgact gatccaacac aagggaaaat
    10321 tttgattgat ggaaaatcca tccaagaaat tgatccagtg gaattgcgac gtcagatcgg
    10381 ctatgttatc caaagtattg gattgatgcc tcacatgacg atccgtgaaa atatcactct
    10441 tgtccaaaaa ttgttgaaag tcagtcaaga agaacggaat aaaacagctg aaaaaatgat
    10501 tgatcttgtg gaattgcccc gtgagatgtt agatcgctac ccacatgaat tatctggtgg
    10561 tcagcagcag cgtattggag tcgttcgtgc ccttgcagcg aatcaagata tcatcttgat
    10621 ggacgagcca ttcggtgcgc ttgatccaat cactcgtgat tccttgcaag accttgtcaa
    10681 agatttacaa gagcgtttgg gaaaaacgat cgtatttgta acccatgaca tggatgaagc
    10741 gattaaacta gcaagccgta tcgccatcat gagtgaaggc cgtgtgatcc aatttgatac
    10801 accagaaaat attttacgtc atcctgcaaa cgatttcgta gaagagttga ttggagaaga
    10861 tcgcctacta caagccaagc caaatgcgac aagagtcggc gaagttatgc taaatacagc
    10921 aatcacgatt acaccggaaa aatcattaca agaagcaatc aaactgatga gggaaaaacg
    10981 tgtagatacg ttgttagtta ccgataattc gaatgtatta aaaggattta tcgatgtaga
    11041 aacgttgaat aaaaaacgag gaaaagtatc cagtgtcggc gacattttga ataaacatgt
    11101 tttttacgta aaagaatccg cctatcttcg tgataccttg caacgcattt taaaacgcgg
    11161 gctgaaatac gtgccggtcg ttgatgaaca gaacaaagtc gtaggtatcc tgactcgtgc
    11221 atcattagtg gatatcgtct acgatgtgat ttggggagaa gatcccgcaa ctactgatgt
    11281 tgcagagtca gctactcctg aagaatctaa ggaggtctga cctatgcagc agttttttca
    11341 tcagcacggt tcagaaattc tctcaaaagg ttttgaacat ctttatattt caggacttgc
    11401 tttgatcatt ggtatcatca ttgctgtacc gcttggtgtc ttactgacac gttttccaaa
    11461 agctgccacg attgtgattg gcttaaccag tgccttgcag acaatccctt ctcttgcttt
    11521 attggcattg atgatcccgc tatttggcgt aggtaaatta cctgcgatta tcgcactctt
    11581 tatttattca ttattgccga ttttacgtaa tacgtacatt gggatgaaaa atgtcgattg
    11641 gaattatcgg gatgtggcaa aaggcatggg gatgactgag ttccaatcca ttttttccgt
    11701 tgaattgccc attgctatgc caacgatcat ggctggtatt cgtttagctg ccgtttacgt
    11761 gattgcatgg gctacacttg cctcttatat cggcgctggt ggtttaggcg atttgatttt
    11821 tagtggactg aataattacc aaccagatct cattttggca ggtacgatcc ctgtaacaat
    11881 tttagcacta ttggctgatt ggcttctagg tctcttggaa caccggctga caccgatcgc
    11941 acttagagag gagaatgaag aatgaaacgt atactaaaaa tgaccatggt tcttttctct
    12001 cttcttatac ttgcgagttg ttccttccct ggtcttgcca gcaatacaga tgaagacacc
    12061 atttcgatca caggtggaat cacttcagaa gcacagatct tagcaagtct agttgccgga
    12121 atggttgaac attatacaga taaaaatacc gcaatcatca acaatctggc tactacaact
    12181 atcaaccatc aagcgatgat gaacggagat gcttcaattt cagcggctcg ctacacagga
    12241 acagatttaa cgactacatt gaaccttcct cctgaaaaag atccgaaaaa agcgtttgct
    12301 accgtgaaag atgaatttga gaaaagatac ggtcaaacgt ggttcccgtc ctatggtttt
    12361 gaaaatacgt atgtctttct tgttcgaaaa gacaccgcac aaaaatacca tctatctaaa
    12421 gtcagcgatc tgaaaaatgt agcggatgaa ttagtagctg gtgtagatac ttcttggatc
    12481 aatcgtaaag gagacggtta tgacggcttc caagaaactt atggcttctc cttcaattcg
    12541 atattaccta tgcagattgg acttgtttat gacgcagtcg aagcaggaaa aatggatatt
    12601 gttcttggct actctacgga tggacggatc gccagttatg atctagtcat gttggaagat
    12661 gatcgtcaat tcttcccacc atatgatgct gctccagttg tagacaacaa gatattagct
    12721 gatacgcctc atttaaaaga agccttaaat aagttaggtc ataccatcag tacggaaaaa
    12781 atgcaggaat tgaactacga agcagataat aatctagtgg aaccatcagt agtagcacaa
    12841 cgtttcttac aagaaaacca ctattttgaa gggaagtgaa gcaattggat aaaatgaatg
    12901 tctttcaaca atttttctat tatttccagg aaaatggctc ctatatcttt gcacaattta
    12961 tccgtcactt cctgatttct atctatggtg tcctctttgc agcagttgtc gggattccgg
    13021 ttgggatcat gatttctagg agacgtaaat tagcaaactg ggtgattcgt ttggcgaata
    13081 tcatccagac gatcccttct ctagccatga tctccatttt aatcattgga ttaggcctgg
    13141 gagtcaatgt cgtgattgtt actgtatttt tgtattccct cttaccgatc atcaagaata
    13201 cgtataccgg gatgatccaa gtagacaaaa acatccttga tgtcggcaaa ggcatgggga
    13261 tgactgctag acaacgacta ttcatggtag agttaccact ctctgtttct gttatcatgg
    13321 caggcataag aaacgcgtta gttgttgcca tcgggataac cgcgatcggt gcattcgtcg
    13381 gtgctggtgg tcttggagat atcattatcc gaggaaccaa tgcaacagag ggcacatcga
    13441 ttattttagc aggtgcattg ccaactgcat taatggcgat catcacggac tggcttttag
    13501 gtattttgga aagacggcta gatccagcca gccgtacatc acgctgatgt tattgtaaaa
    13561 aacaaaagct tctgcgacca tttgttggtc gcaaaggctt ttttagttct gtcattttta
    13621 aggcaataat ccactctgat tcttccctcc ttatgggcaa agagttgctt ttcttagcta
    13681 tttatccatt ccgtatactc caacttcata ctgccaacgg gttcatatct gcatccaccg
    13741 actaagtttt tttcttatcc gctaaggcat tttgccaatc cattttccca tcactcgtca
    13801 tggaattcat accacatgat ctctaaatac tcgtctgctt gttctttgaa ttgggcatca
    13861 attcttacat cctttggcgt ggctttcatt taagcctttt ccatcagtcc tcgattgttc
    13921 gatgccttca gctgcatcat caaaactggt gactgccgta tcggtaactt cgatcatctt
    13981 ttatacaatc gggaacttgc catcctcatc cttggctaaa aacatatcta gccattccag
    14041 cttctcgcca tgggaggttt gcggttccta aaaccggtac acgattctta tggactgcat
    14101 ccgtcgcaac tagacttggc gatacgatga tccttcacca gaagagcacc cccgtaaacc
    14161 aattgatcga tatattgcca ataagaaaag acattggcgt aaaagatatc gatccctcgt
    14221 gatgcattgc cgttgatact gctattcatg gccgaaagcg ccacgacttt aacttcttcc
    14281 gtttgagtga cattcatgtt cggcaatgtc gctttggata cccgctctgc taaaggaacg
    14341 acactggtat tgtatttcgt atctgtatct tttccaaaag accatgccaa cgaatcctct
    14401 gggaaccaat aagacgactc cggttgattg tccattgctt ttttcaacat acttttggct
    14461 gtttctcgat aaacgacatt tccaattgtc ttcgcctcac tttggcgata atcgatggtc
    14521 gttgccactg ccaacactaa caacgatgct ccaattttac tgattttcct tgtcacactt
    14581 cttcctcctt gttttacata aacccgtcaa cattccattc ctaaactcaa acaatgaccc
    14641 ttcaaaggtg gagatatagg aacaaattaa agaaatcatg caataaatcc aagaaggttg
    14701 gttttagaac aaaaaaagag tctccttttt ggggagactc tttgttaact atctaaaaag
    14761 gttggctctt ctcacttcac tcataatgtg tccaggcaga ataaatttct acaactttat
    14821 tttcctcatc aactttgtaa accactcgat gctgtctatt cagcctgcgt gagtatctgc
    14881 cttcatgtgt aggtctcagc ttttcaaaag actgcgtggg catatatgga tcttccttca
    14941 atgtctgaat cacttcttca aattgtttct ttaaattcgt ttgcttgatt tttcttaaat
    15001 ccactttcgc agagtttttg attgcgactg tatagttact catcaaagag cttcccaatc
    15061 aatatcatcg atattcgtaa agctactgtc gtctttttcg cggtctcgta ctttatctaa
    15121 agtacctgtt tgctcaagaa aaagggtttc ttgaatcgct ctccagtctt ccagcccaat
    15181 caatacagca ttgtttccac tacgatcact aataatctcg atttcagtat gattttcatt
    15241 tacctctttc aataactgat aaaaattttt acgagcagtg ctaggattca tcgttgtatt
    15301 agccattgtc tctcctcctt tttctgatat aattatagcg tacttgatta agtacgtcaa
    15361 aaaaatacaa taaagcactt aaattcagca aacttttcct cttttttaca tagagaaaaa
    15421 gacccctttt tagggaggat ctttgtccac gctcacttct tactccttta cgactagcgg
    15481 tagccaaacg taaagtaatt ggtaacaacg tatcatcttt agcaaaggtc gaatccaaag
    15541 cctgtgagtc tatgcaacaa caccaataca cgaaggttcc tcgttgcagt gtgacttgat
    15601 tgatatcttg aataacctga ggatacgcac gaaagatttg taacggttat tcaaaactga
    15661 ttttggccgt caagtcttct actgcctcaa aaatgattgc ctctttcgtc tcctgtcatt
    15721 catgttcact atcgatttga tacttgctta gaccgttggg tttgtgaatc accaattaaa
    15781 aatggcactg agttatggta acaaaaaatg gtcacttgac gaggctgaga ttcctactta
    15841 tgaagacaca tggcacttaa gagtcgaggt aaaggaagaa gctgaaaata taggaggctg
    15901 tacattattt ggcaaaggat tcggaaatta tgatcaagac atcaaaatca aaatgtttta
    15961 cagctaaata ggaagaataa taacatttca tacgctgttc ccatctttaa tggcttatag
    16021 agggcacctt tagctgagaa taagacaaaa cagaccctct agcttcaatt aagagctaga
    16081 gggtctgttt ttgattttaa aacttggttt atttcttcaa atggtagcta taggtgctga
    16141 caacgatatt ttcacgccaa gacaatcgca atcttaaccg caaacttgtt tggttatgga
    16201 gaatattctg ccagcgtctg tttggtacaa attgaggaat caacacagta gttgtatagt
    16261 tttgtttcgc tgcattttta cttacgatat ctacataacg gataattgga ttttcaatcg
    16321 agcgataaga agagtggacg attgaaaaac ggacatctgg gaaatgcttt ttaaattctg
    16381 cttcgatttc tttttctttt tcgacatctt cgtctagcga aacatgcatc gcaacgacat
    16441 aatcaccgat cgaacgtgcg taattcaacg caccgatatt tacccgtgtc acattcccga
    16501 ctaatacaag aacggtattc ccgtcataat catgtagttt tgcatcattt tctaaacgaa
    16561 gctgttctgc tactttttta taatgatcat ggatcttata aaaaatgaac ataacgattg
    16621 gcataatgat gaagaaaggc caaatgtccc ctaaccgata gacaaacaaa atcgcaatga
    16681 ttgcatatga gatgaacgca cccgtaatat tggcaatcga tttgcttaac catctttttc
    16741 cttctttttt ccatttgacg accatccctg tttgagataa agcaaatgga atgaacacgc
    16801 cgatagagta taacggaatc aagcgttctg ttgagccatg gaaaataaac agcaatacga
    16861 tcgaacctag cgctagtgtg ataatcccat tggaatagcc tagtcgatcc ccacgatctt
    16921 gatacatgtg aggcatgaat ttatcttttg ccagattgta tgcaagaact ggaaaagcag
    16981 aaaaaccggt gttagcagca actgctaaaa tcagcgctgt agcaaattga aggacgtaat
    17041 acaaaatacc atgtccaaag acagctttac caatttgaga caaaacagtg acttcttttt
    17101 caggaacgat cccataccaa tagttgataa atgtgatccc cacgaagaag aaacctaaga
    17161 tcaatgccat catcgtcaat gtagcagcgg cattttttgc tcttggcttc ttaaagaatg
    17221 gtacagcatt actaatcgcc tccaccccag ttaaagagga agaaccagaa gaaaatgctc
    17281 gtaaaatcaa agcgatagaa acacccggca cagccgctcc tggaagtgca gtagcttgca
    17341 atggcacagc acctgtcacg atattatata aaccaacaac gatcagtaac gagatcacaa
    17401 ggataaatgt gtacaccgga aataatagga acgatgcaga ttccctcagc ccacgaagat
    17461 tcagcatcat cagtagcaaa acgattgtca cagaaatagc gacttgatga ccgtagagtg
    17521 ctggcaccgc tgatgtgatc gcttcagcac ctgctgagac agatactgct actgtcaaca
    17581 tgtagtcgat caataaagag ccaccggaaa tcaagccagc attctttcca agattctcac
    17641 tgctgacgac atatgctccc ccgccatgag gataagcatg gatgatttga cgatatgata
    17701 gcgttaatga aatcaataaa ataataacaa aagcggcaat gggtagcgaa taccagatgg
    17761 ctgcagcaga caaagcgact aaaacgacaa cgatttgttc cgtaccatat gcaatagatg
    17821 ataacgcatc agacgacaat aatgccaaag cagcaaatcg ggttaatttg tgctcatcat
    17881 tttcagcaga ttttaaaggc ttacctacta acaacctttt taagtaatcc aatttctaaa
    17941 ctcctttaca cacaatttta cttcaagttt tatagtcgaa aatttatagt aaacaagatg
    18001 ttatagtacg ctcactgacc ttaaaagtca ataaacttta agaaaataat tggaaaaaaa
    18061 cagaaaaata tcaagcgctt tttcaaacgc tttaatacag caaaaatcta acattttttt
    18121 atgggctttt tctttgaatt ctataataaa aggatagaac ttgacttaga aaatcaagtt
    18181 ctatcctttt tgatatctta acttttggaa gagagatgta aggctgcttt ctacccatca
    18241 ttcttactac tcgaagcata gcgcagttgt cacaacctct tgataaacgg tgtttaaaag
    18301 cttgcatctg cggtaataag ctcaaccaaa ttaaaaacat aagaagctgt ttttatttgg
    18361 tcgttcttat tacttgatgc agagcagctt ttttacaacc tcttggtaca cggtgttcaa
    18421 tcagctgacc ctcggtatta gctcaaaaaa acggcaaaat atgaggaact atttttccat
    18481 ttttttctct aatactcagg tcaaaacact gatttcacaa cctctttttt taatgaaaaa
    18541 tatggctctc atgcgccgct tctttgaatt tcgtcatttt ttcttcgatg aacggataga
    18601 ttgccgttcc tacgattcca aagacaacaa acaaaccgat catgatccag attgctttcg
    18661 tagcatttgg ccaataaatt cctcctgcag attcccgtaa caagtttacc gcatgagtaa
    18721 atggcaagaa cggattgatc atttggaaga atttccctga gacttggatc ggatagttcc
    18781 cgcctccgcc agagatcgac agtactaaga tgataatagc gatcccttta ccgacattat
    18841 cgaataatgc agccaagaca tagacgatca tcatgaacgc taaggcgatc aagacagcaa
    18901 atgacacgct gtagaccgga ttttggacat ctactcctag taagaaaata ttccctaatg
    18961 taacgatcaa gctttgcgca atcgccattg tcaaaaatgt cagcatacga gcaacgaatt
    19021 gttctcgttt cgtaaaattg tttcggtctt tctttcctaa atagtattct gtcgtagcaa
    19081 cacttgaaag aagaacagcg ccgacccaca gacatagtgc agtataaaac ggggtgctag
    19141 ctgaaccgtt atttgcgatt ggataaagcg cattggtttg tagctcaaca ggttgtgtaa
    19201 agaagtcact ttcttttgtt gcgtctagtt tcaataattt gatgacttcg cctagatcga
    19261 cttcttgttc gccttttcgg atcgcgtctg ctgctttttg gataccagct ttgatatttg
    19321 gccagtcatt gttgatcaag tccgcagcag cgttcacagc tgtttcgact tctggcattt
    19381 tttcatttac tgttgtcaat gtaccggtga tttcattttt tagtgctggc caatcatttt
    19441 ggataaaatc agcggccaat cctaattttt gctgaatgat cggtaattca ttgttgtata
    19501 ggtctgcccc ttcattgatg ccattgacga tggtatccat atttccattc agcattgtat
    19561 tggcatcatg gatttcttgt ccaattgcag gcatttcttt ttgatatttt tctaaaattg
    19621 ccactgcatt cgttacagtt gctttcgttg agctgagaag cgaatcaaag tcgatctggt
    19681 ccgctttgct cagtgcgcct tgtgcagtcc caatcgtatc gatgacttgg tctagtagag
    19741 aagtgacagt ggaactgatt tgacctgtat tgataccagc aatgatgcca ttgatattat
    19801 taacaacggc atcaatttga tctagcaatt catcaatagc cttcgtgtct tcattttgaa
    19861 cagctgtgtt caaagcagat aggcggtttt gcagattgct tagcaagggt tttaattgat
    19921 ttagctgatc aataattggc tgtaatttcg tatttccagc acttgtttgc aatttagtca
    19981 ggaactcgac cagtttatcg attgcatttt gttgttgaga tattccgtca ataaagccgt
    20041 tcaatacatt gctgatgttt ttcttttcat catcagtcag cttaccatct tcaatagctg
    20101 ttcttacagt atctattaac gaacctgtcg ttgttgccac ttgtccaatt gacttcaatg
    20161 taacatctac actgtttgtg atgcttggta tcgcatcttt cagctgagag gcacctgatt
    20221 ttgtttggtt tgctagatca cttgcctgat tttctaaatt tttcacatct ggcaagatat
    20281 cttgtacttg ttggatgatc gtcaagcctt gttttgcttc atcgattcct tggttcattg
    20341 tctcttggat cgaagcaaaa tcgccgtcga tctctgctag ttgcttaccg gcattttgga
    20401 tctctgggat tttttcttgc aaatcaagga tgatttttgc ttgatctttc aactcaggca
    20461 ttttgtcatt caatgcaacg actttttcac ccatctcatc tactttaggg atgtaatcca
    20521 cgaattcatt tgctttattc agtttttcct tgatttcagg tagttgactt tgtaattcga
    20581 ggacttgttt tgtgtagccg tcgatcgtgt ccaaattttc atctgttgat aaaatcatat
    20641 ctttaacttt attgatactt actaggttcg tatcgatgtc gtaacctatc tcattgaata
    20701 ctttcaataa agtcgaactg gctgttttga taaattcatt tgtgatttgc gattggatcg
    20761 aacttgctcc tttatcggtg attttcggtg caatcgcatt gattttttca tttaccgtat
    20821 attcgatttt tggtttcttg atatcaccac tagtaaaact cagcagatct tctgagaaat
    20881 cctttggcaa gtaaatacct gcgtaatact ttccggaacg gactccgtct tctaattgtt
    20941 cttttgaatc aacgaattgc catcctaatt gtttattttt atgaagcgat tcgatgactt
    21001 gctccccaat ggccacttct ttaccttgaa actctgctgg cttgtctgca ctgtaaacag
    21061 caattggcag ctctccagta tttccatatg gatcccataa tgctttgatg ttaaaccacg
    21121 catatagcga agggatgatc atgatcgcga tgatcagaag tgttgcaatc gggtttttga
    21181 aaatccgttt ccagtcaagc aaatataatc gaagcgtatt tttgattgac tgcatagttc
    21241 tcccccttct tcttttttca gctgaattac tttaccatgt atttcatact tttttcaatc
    21301 ggcttttttc aaaaaagtcg aatttttgga catatcacgg caattgtctc attgtaatct
    21361 cttacatatt gagaaataat taaggattac agcctttact ttatcatgaa ataaaaggga
    21421 aagataattt tatgccaaag tttttatcta ttatacgtat acgcaaaaaa gctaaaacat
    21481 tttttgtctt tgcccctaca aaaatgtttc agcttttttc gttttttatt cctgtatttc
    21541 ttatttttcg aatgacagga tgattttccc agcaggagga tgtccttcaa ctagctgatg
    21601 tgcttggatg acatgcttaa gtgaagcaga cagattcatt gaaataaaaa catgaaaggc
    21661 tcctttttgg taggctttga ttatgccagc aaaggcttct gcatctagat attcctttct
    21721 tggaacaaac gattcataaa agccttcctt tttttgccgc aaatctagat ctgggaggtc
    21781 atttaatgca acatacctgc cgcctggttt catgatctgg atgccggttt ctcctttgat
    21841 acttcctttc gtcgcatcga ttacaaggtc tgcctgatca gcaaattgca gacctggatt
    21901 tgttttatca taagcagcaa atgctgaagc tcctaatttt tttacctttt cctcattttt
    21961 actggatgca ctggttaaga ttcggattcc cttttcatgg agaagctgga tcagacttga
    22021 cccgaccgca cctgatgctc ctagtatcat tacagtatct gtcggctgga tttccgtcaa
    22081 atggttgatt agattataag ccgtaattcc tggcgtgacc attccggctg cttcttccca
    22141 actcatttta tctggaattt ttgctacttt tgctgatggc aacacgactt cttctccgta
    22201 agtcccgccg actgcatgga cagctactcg atcacctaca tgaacagttg tgacatctga
    22261 accaatctct gtcacaatac cagcgccatc attacctggt acataaggga atttcaatgt
    22321 tcgtatctct ttcatttctc ctaaacgcaa ggcaacatca taaggattca cactgaatgc
    22381 ttttatttct acacgaacat gtccagaacc gacttctctg ggatgagcat cgatttcttc
    22441 aaaaacatct tgtgcttctc cgtaaccgtt aattgcaaat cttcgcatgg tcaccatctc
    22501 cctttttctt taagtttacg tttatgtctt tattttgaca aaaaaaatgt cttttcgttt
    22561 tggcgcatga ttcaaaacaa aatagttgtc ttttttcgcg taacgtgtta aattatttat
    22621 ctaaaagcgt aaagattacg atttacgcta ataaaaaata attggaggaa tttgttgatg
    22681 gctaaaaaat caaagattgc caaagcaaaa aaacagcaag aaacgattga acgctatgct
    22741 gctttacgcc aggaattaaa agcgcaaaaa gattacgaag gcttgcgtaa acttccttta
    22801 gatgctcgtc cagaacgatt gaaaaatcgt gatttaatcg atggacgccc tcgcggatac
    22861 atgcgtaaat tcgggatgtc ccgtataaaa ttccgtgaat tagcacataa aggtttgatt
    22921 ccaggagtaa aaaaagccag ctggtaatcc aagtctggct gtaatgtaaa ggaggagggc
    22981 gcatggacca ctccttggat catcaaaaaa gatacgttcg cttcttctag cagaaatgct
    23041 ggtactagaa gcagacgtat ctttttttac gcacagctgg tcctttttta tatgtaaagg
    23101 ctgcatggtt acttcgctat atttatttag taacaggagt cagtgcttcg atacccacac
    23161 taattttcaa tgctcggtca acttctgcca taatgggtcg atccaaatgg cagacctttt
    23221 ctttcaatct tgatttatcg atcgttctga tctgctccaa caggataacg gagtctcttt
    23281 ctattcctgt tccagtagct ttgatcccaa tgtgagtcgg aagcttaggt ttagccattt
    23341 ttgccgttat ggccgcaaca atgatcgtcg ggctaaaatg gttacctaga ttattttgaa
    23401 taaccaaaac tgggcgtgtt ccgccttgct ccgatcccac gactggagaa agatcagcaa
    23461 aataaatatc tcctcttttt accataggat cctccttatt cttgatattc tcttggtatc
    23521 cgctgtccta atccgcaagc cacttcatag tggatcgtac ctaattgatc tgctatatcc
    23581 tgcatagtga tttctttgtc tgcatttttg ccgataagcg tcacttttgt tccgacagga
    23641 aattcttgag gcaatcggat catcagttga tccatacata cacgcccaat cgtttcacag
    23701 tagttccctt ctaccaatag agaaaaaccc tgcatctttc gtggccagcc atctgcataa
    23761 ccgatcggta tcgttccgat ccactctgct tcaggagtga tatatgtttc tccatagccg
    23821 attccttcac ctgctgggag ttttttgact tgaatcaatt cagaaaccag ctcaagtgct
    23881 ggctgcaatg gataaacttc cggtagtgcg tgcccagagg gattaagtcc gtacattgct
    23941 actccataac gaatcatatt gccgattgtt tcatcatgcc ataaagccgt tgcactattg
    24001 ctgacatgta catatcgagg aagttcggga agttttttca gcacttctat aaagcgttct
    24061 ttttgcagat tccaatatgt atcatctgcc tgatctgctg tagaaaaatg ggtaaataaa
    24121 ccttcccatt ctaatacacg actttctttg atgaatgcag ctgcctcttt tacttcttca
    24181 ggtgtacaaa atccgatacg acccatccca gtgtctgctt ttagatgaat cgaaagaggc
    24241 gtctctagct tacttttctc taaaacagca gctgctgctt gcaaccattc ccgtgtacct
    24301 gcagttactg ataaatcatg agcaacagct acagtcagtg cgtcgtaagg aaccatattc
    24361 aagataagga tgggctgagt aaatccagct tctctcaact cgactccttc atctaaattt
    24421 gaaacacaaa agcccgaagc tccacctgca actgctgcct cagctgtttc aatagctcca
    24481 tgaccgtatc cgttcgcttt tactactgca aacaattctt ttccttgcgg aagtcttgca
    24541 acttcatttg ctacattttc agttatagct tttttatgta tcactgcttt cgttgggcgg
    24601 tgccaagcga caaccatcgt ttttccttct ttctagtctt ccaaaataat ttgtgcaaaa
    24661 gctgtttcat ttgtatgagt aatactgacc catacattgc cttcatgagg tgaacgcgtc
    24721 acaacaggct gaccattttc attttttaaa atctcgacat cttgaaaggt aacttttccg
    24781 atcccagttc cccaagcttt agagaaagcc tctttgcaag cgtaacgccc gcctaaaaat
    24841 tctacttggc gatgaaaagg caaggactgg aatagtttca tttcatcaga ggtcaagatt
    24901 cgtgcaatga attttggttt ttcttcgatc agccgagtga tcctaggaag ttcgactgca
    24961 tcgatcccaa ttccttttat catatgcttt tctcttttca ataaatttag aacactctca
    25021 ttctaccaaa ttataaccat tttgccacaa ataagtccac aaataacaaa aatgaaagtt
    25081 tctcttaaaa aagagaaact ttcattttat gtttaatcgt tatttgaacg gattacaaat
    25141 ccgcgttttt tatcattgtg acgtttaccg ccatcttttt ggctgttatt atttttgcta
    25201 taaccgcctt ttgatttgtt tccacgataa ttaccgccgt cacgacgatt acggttgttt
    25261 ccgccaccac gtttgccatt tttattgtat ccttttttct gcattggcaa tgggcgttct
    25321 ggtgtgatct tcactggcac tgcatcagct ggatcttttg ctgtcgtttt tagcaaaagt
    25381 gcaactaaat cttgtgcaga atattcttct aataatttat ctgctgtttg caggtattta
    25441 tctagaccat tttctgcaag ttttgtttcg atttgttcaa ctgcagcacc taattgacct
    25501 ttgaatgctt ctttttcggt tggtggacgt aaagtcgtca tccgtttttt cgtcaagttt
    25561 tcaatcacat gcaagtagtc catttcattt ggtgtaacga aagtcacaga cataccgcct
    25621 tttccggcac ggcctgtacg tccgatacgg tgaacgtagc tttctggatc ttgagggata
    25681 tcatagttgt acacatgagt gacacctgaa atatctaatc cacgtgcagc aacgtctgtc
    25741 gctacaagga tatctaaatg accgctctta aatgaacgca atacgctcat tcgtttttgt
    25801 tgagacaaat cgccatggat tccttctgca cggtaaccgc gtgcttctaa tccgcgtgcc
    25861 aattcgtcta cacggcgttt tgtacgtccg aagacgattg ttaattcagg tgtttgaaca
    25921 tcaaacaagc gagtcatgat atcgaatttt tcgtattctt ttgcgcggac atagtattga
    25981 tcgatcaagt cagctgtcat ttctttcgct ttgatcttca catgatgtgg atttttcatg
    26041 aatttaacgc caatattctt gatagctggc ggcatcgttg ctgagaaaag taatgtttgt
    26101 ctttgatcag gaacttgtga aatgattttt tcgatatctt ccaagaagcc catattcaac
    26161 atttcatctg cttcatccaa aactaatgtt tgaacggttc caagtttcaa tgtgtggcgg
    26221 ttaatgtggt caagcatacg tcctggtgta cccacaacga tatgtggacg atctttcaag
    26281 ccacggatct gacggccaat atctgctccg ccgtaaacgg cttgtacacg tacttttttg
    26341 tcgcgcccta aacgatataa ttcttcttgt gtttggatag ctaattcacg tgttggtgcg
    26401 ataactaaac cttgtaattc gtgacgatct ggatcgattt tttctaacat tggtaatcca
    26461 aatgcagctg ttttccctgt acctgtctgt gcttgtccaa taacgtcttt tccagctaat
    26521 gctagtggaa tcgtttctgc ttggataggc gttgcttctt caaaaccagc gcgttcgact
    26581 gatttcaaca attctggtga taattctagt tctttaaatt tcaaatgaat cctcctatat
    26641 ggttgttaac tgaggatgta gcttttttgc taccccgtcg atttgttcgg tcaaagtgta
    26701 ttgtttcttt ttgacagtgg ccacgcacgt ttttatccat tcttagcccc tgtggcacca
    26761 ccgaaaaatc actttgcgaa gtttaggcat tagaaaagcc aaacgggtcg cgttcagctt
    26821 tatcattatt atgacatctg gcttcaacaa gttgtttcta tggcaaaacc agtccaattt
    26881 ctcttcatct ttcggcaata ggttattcta acatagtttt tcgttttctg caagtttaca
    26941 gatttttatt tcatttgctg aagttgttct accacttcaa ataagcccat gctgttgctg
    27001 ccttttagca taatactatc tgttgctgca agattttgtt tgatagcatc aatcaattta
    27061 ttcttttctt tttcaaaata gaacacaggt agttgggggt atttttggtt caattcttct
    27121 tttagtgcat gcatttgttc cccataaagg aaaatcatgg cgaatttctc aggatcgata
    27181 tgttcactca tttgcgcatg catatttaaa gactctttcc ctaattccag catatctgct
    27241 aacacagcga ttctgcgtcc ttttgttggc agatttttaa aagtatctaa taccagtccc
    27301 atggctgttg gatttgcatt gtagacatcg ctcaaaatag ctgcaccatt tcctgccgtt
    27361 agccattcgg ttctgttttg agtgatagaa acatgggcga gcccttggcg tatctcaggt
    27421 atggacagtc caaagaagcg cccgatcgta tacgcaatca aagcattcgt tacattataa
    27481 cttccaggca gcgggatcgt aaatgtttct ccttctacta caaaatcggt ttgtgctttt
    27541 ccttttgctg tcacttccgc atgaacatcg ccatttccaa taccgaatgt tgtgactgtt
    27601 tgtactaatg ttgccgttaa aggtgtcagc aacggttcat ctgcgggcac aacgagtaat
    27661 ccgtctgata caagtccgtc agtgatttcc attttggctt tagcgattcc ttctcgcgac
    27721 ccaagatttt ctatgtgtgc ttcaccgatc attgtgattg ctgcagcttt tggttgagcc
    27781 ataagtgaaa gttccgtgat ttcattggcg tgatccatgc ccatttccaa aacgatcttt
    27841 tctgtatctt ggggcatgtg caaaatcgtg taaggaagac caatattatt gttgtaattt
    27901 ccttgcgtct tatatgtttt gtatttttca gacaagacag acgcggttag atctttcgtg
    27961 gtggttttac cattgcttcc tgtaattgca acgacttctg cgcctacttt ttccaagtaa
    28021 taggttgcca attgctgcat ggctttcaaa ggatctgcta caggaataac tggaaaattt
    28081 tttggagctt gttcaacagg caagctccaa aatgaagcag atgctccgtt tgtgatcgct
    28141 tgctggataa attcatgtcc atctcgcgta ccagcaagag gaacgaataa acttccttcg
    28201 gttatcttcc ggctgtcaaa ttcgacattg gtaatctttg tcagtgcaga gcattcgctg
    28261 cccacggctt gtgcaatttc ttgtattgtt agattcattg agatctctcc taaaaaaggt
    28321 tgtgaaaaaa gcgtttggcc taaacggcgg gttcgcatga ctctcacttc caagtaaatt
    28381 tctctattcg tatttagaag ctagaatgaa cgcggttacg caatcactcc agcctcttct
    28441 ttatttctct ttattcattt ttttcaaaaa aagattgacg ctgatggtat cgattcattc
    28501 ctaactggat cagttcttca atcaaatcac cgtatttcaa gcccatattt tcccataaga
    28561 gtgggtacat attgaactcc gtaaatcctg gcatagagtt taattcattc aggaataatt
    28621 catttttatt tgtcaaaaag aaatcgcacc ggctcaatcc gcttccacct aacatcgtgt
    28681 aagctaactt cgcgtactct tgcgcttttt gataaacttc ttctggcact tcggctggaa
    28741 tctgcatttc gattttatta ttgatatatt ttgcttcata atcatagaat gctacgtctt
    28801 ttacgacttc accaggcaaa gtcgtccgaa cgtcttcatt tcctaataca gcaacttcga
    28861 tttcgcgcgc ttcaattcct tgttcaacga ttgctcgaga atcatactga taggctgttg
    28921 ctaaagcatt ttgcagctct tctcggtttt ctgcttttgt aatgccgaca ctagaaccca
    28981 tattcgccgg tttgacaaac atcggataaa gcaaagaacc ttcacattga tcaaatactt
    29041 ttttaggatt ttctttccat tgattcttaa gtactggtac ataaggaact tgcggcacac
    29101 cagcagcttg taaaatatac ttggtcatga ttttatccat ggcacatgca ctggtcaata
    29161 cgcctgcgcc gacataaggc atattcaatg tctctaagaa gccttggatc gttccatctt
    29221 ccccgtttgg cccatgtaaa actggaaaaa cgatggctcc ttcttctttg atttcgcccg
    29281 gattgatcac ttttcctgta aagccttcct ctgtctgtcc acttgggtcc catgaaagat
    29341 gcaagacatc tttgctggca ggtttttctg ttagtaatgg acctttgacc cattgtcctt
    29401 cttttgtaat aaatacgagt tgaacttggt aataattata ataaatggca tttaaaactg
    29461 aaaatgcgga aagaatggac acttcatgct ctgcgctgcg tccgccatat agtaaagtaa
    29521 tcttcaaaag attgtcctcc tgtattctaa atcgttcagt gatttactct catattttag
    29581 cacaaaacaa aaataaacga ataacttatt tataaaaaaa cgagccagct tctaaaagaa
    29641 cgagcgtcat ttattttttg tcagctagat tatttgtccc gttttttata aaaagttatg
    29701 ataaagaaaa ggagggatga tgatggcgca aacaaatcca cgcagccgct tggcagaaat
    29761 cattcgagtg ttcatcaatt acaatgtagt gccaaacttt gtacagcaaa aaaatcccga
    29821 acaggtaaaa aaagcctttg aagaactagg ccccaccttc atcaagatag gacagatgct
    29881 ttctgttcga gaagatttgc tttcttctgc cttcactcaa acattcaaaa cattacaaga
    29941 tagtgtacct agcgacacat tttcaacggt caaaaagacg atcgaaacag aactttctct
    30001 ttcattatca gatatattcg atgatttttc aaaatcgcct tttgcctctg cttctatggg
    30061 gcaggctcat cgtgccaagc tgaagaacgg tgacgcggta gtcgttaaga tccaacaccc
    30121 taacatcgcc gaagagatcc gacttgatct tcaactattt gaacgagcga tccctttgat
    30181 caaatacatt cctgaaacta gcgtagttga tctaaaaggg gtactccaag aagtaaaacg
    30241 ttccttgatc aatgaaatgg acttcttaaa agaaagtcaa aatggcgaac aattctatca
    30301 aaagaacaat ggctggaaag agatccgcag ccccaagatt tatgacgctt tttgttcgaa
    30361 aaaagtgatc gtgatggaag aaatgtctgg taaaaacttg aatcatttaa tgaacgccga
    30421 aaacaaaact gaaactttta tcactggaat tcaaaacaag cagctgaaac aagaagttgc
    30481 aaagctttta gttgagaact ttatgaaaca ggtgtttgat gatggttttt tccatgctga
    30541 tcctcatcca gggaatctgc tattccatgt actaacaaaa gaagaacaga cacaagctag
    30601 ccgaaaaact gaaacagtcc atgaaaaaga gttcggttcc tttgcttttc gagcctccac
    30661 ttctgcagaa gaccctgttg cgccatatac catcaactac atcgattttg gtatgatggg
    30721 gcatctttct gcaggactta ggcaaaaact cacacaagcc gttttagcgc tgtatacgaa
    30781 agatgcttat cgaatcgaaa aagcggtcct tcgactttgt cagcaagaag gctcgtttga
    30841 tgaaagtcgg ttccaccaag aactgacaag ttttcttgaa cagtattatg attctcctat
    30901 tgatgaaatc aacttgcaag aagtattcac acatgtcgtg acgatttgtc atcaaaataa
    30961 tctgcagttc gatcgtgata tcacgctttt gctgaaagca tttgggacat tagaaggggt
    31021 gatccgcgtc ctcgatcctg aagtttccct catggaagtc gcttcgcctt ttgctcaaca
    31081 ttattttctc actcatctgg atgtagaaga tacattgaaa caaagcggat tagacttatt
    31141 ggaagggatg aaggctgcgc ctaagatccc tcaacagctc caccatctat tagaaatgtg
    31201 gacttcggga caaggaaaag tcaatttgga attgaaaaag caagacaaat tattgagcag
    31261 gatcgaaagt atgatcaatc ggcttgtttt cggtatgatt ttagctgcat tgatcgtagg
    31321 gtcctccctg cttgtccaag cagcacctgt agaaaacgca gaggtcgttt ccttattagg
    31381 gatatttacg tatgctattg ccgcattcgt cattattttt ttggcaatcg atgcattgat
    31441 ccaaatgtat aagaagagga aaaagtagaa aaaggttgtg acagaaagaa tcagcttcaa
    31501 gaaataagaa ggggttttac ataaattgtt tctcaaattt ttgtgaaaat tcggcttatt
    31561 tttcgaagag gctacttctg aaacaccgag aataaaaaat gtgaaaaagc tgttctgcac
    31621 ccagtaataa gaacaatcaa aaagggaaca tggaacacat ttatcctgtt tccctgttcc
    31681 ctttttgatg tattcgagca taaataaaat accttcgtta cctactatct tctgtacttg
    31741 gtaaacctta gtcaattgcc ttttttaacg cttgacgaaa agacatatga tctttctccg
    31801 taaagggttt tggacccttt gtccttatgc cagcttttct taactttcca ctatgataac
    31861 gttgttctag aagcgtgccg atattcgctt cgtcaaattc ttttccagag tgatggaaca
    31921 ctcgcacacc cttcggcaat acaagtgaag ctaaaccata atcttgcgtg atcaaaaagt
    31981 cattcttctt aaccataccg acgattttat aatccgcact atcagctccg cggtctacgt
    32041 agacgatttg gacatgatta gcgtattctt tggtcgtata atggtccaca ctggtcacga
    32101 taaccacgtc aagaccatag gattctccta attttatgac atcttctttt actggagaac
    32161 catctccatc aatgaatagc ctcattcttt ttcgccttct tccataaatg ataaacagtt
    32221 actaatccgc tcagtaaaag accaacattg atccattttg ccaagataag cagttgtaca
    32281 ctttctatcg gcactgattc atggttcagc gtgatcaata atagatggat tggctctccc
    32341 atttcttttg ctaaaacaaa caaaagcgtc atcaataaaa actggtggat cacactccct
    32401 ttattttgag tagtatactt gacaacgatc cggcgatcca ttggaatagc tgtatcagtt
    32461 tgataatatt ccttatttag ccagctgcct gttactacgt gccagaaact aagcagaaag
    32521 acacctatcg caaaaccatt tggaatcaag aggaccaata aagaagaact cagtccaagc
    32581 aattgcatag ccaatggaga ccatgttaaa cgtttcaaaa tccatggtcc gactattttt
    32641 gctgcaatca agcctgctgc ataaggcaaa tacataaaaa tcgaaagttt ttctaatccg
    32701 tacagtatgc caacataaaa actgctaaat aaaaaaagga aattccctag cattccattt
    32761 agaaaagtaa acagatttag ccagcttggc aacttccatt ccttcttctg gtgtcctaaa
    32821 acaaacacga acaagatgaa cagcagcaag aaaccataaa tagcaagatc aaaaagcctt
    32881 tcatcgaata acaatcgggc atttctcaaa agaaacaata agccaaagaa tatcaaaaat
    32941 aaaacaagct ctcgcgtagc taccagattt cttttgatgt ctttgaaatc cagttcgtaa
    33001 cgcggataat gactaaccgt atggtaggcc atgacgtaaa aaagtgtata aatagtaaag
    33061 cttgctgcaa tctgagtcgg tgcaggcaac tcaatcgctt gatacaggag aaatagccag
    33121 atagctgcaa ataagtactt tttcccatcc atattgataa aaccttgcgt cttttcgtga
    33181 aaattgaccg tggtattagc aggtacaagc catgctgcac tcagccctag caaaacactt
    33241 gaaaaataaa ataaaggaaa ataaaatacg cctaatattc caagcaatga accagcacca
    33301 ccaatcagca gagcgatcat cagcaacgtg taactatcta gaccaaatcg tagactgttg
    33361 actaaaaata gtccagtcat ccgaaaggca taaaacagcg taaatggcaa aatcgtcagc
    33421 caattatgcg agtctgttag tcccaaaaat aaaagataag gaataaaaat aaccgtgtta
    33481 cttaagataa agggcgttgt ttgtgtaaaa ttacgcccaa atcgtttgag tttttcgaac
    33541 atgacaatgg ctccttaaac agtcttataa ctaatctgct cttcgatttt agcattaaag
    33601 gggaaataaa ccaattttac agaatatatt cttgtaaaaa aaaatacaga aagaagcata
    33661 agcttctttc tgcattttta cggtacttga ttactcaagc agacaagccc ttctccacaa
    33721 aagtcttgcc cgacacccct gcatccggca ggtgataaag atagaaatca attatcctgt
    33781 gcctccaaaa tcaattagga gctctgtaaa ccagagtcct tctcgacccg tcgcataaat
    33841 ttactttaac acagttccta tgtttatgcg agagcttttt tcattttata atcgaccatt
    33901 tgaaatcctt gaccgatatc tgaaataagt tcttctgtaa tctcaaatcc ttcatgctta
    33961 taaacctcga ttgcttgatg attcccctga ttcactcgca aaaagatctc tctttccttt
    34021 gtttgcgcag caagttcttc ataccagcga aaaactgaag aagtcaatcc ttgaccacgt
    34081 actttattta gcaaatataa tttacttaaa taaatttttc catttatctc ttcataagca
    34141 gtgtaaccga cagtcttttc ttcgcttttt aataaaaagt aggacacacc ttctgtcagt
    34201 tctttttgaa tctgtttttt tgactgataa gttttcagca tgtaatccac ttgtttttga
    34261 ccaatgatcg gcacaaaagc ttccggccat acttcttgta tgactgccat cagctcatcc
    34321 agttcatttt ctgttacttt tattttttcc atacacccac gtcctttttt acattataaa
    34381 tgaccttgcg cttgatggaa taaaaagagc atgatcatgc tatacacacc caccgaccat
    34441 ggtttcaaga aaatcacaat ctgcataaat tccctaaaag ataatttcgt caaaccagct
    34501 actagacaga tcaagtcgtc tggcgcaaag ggaagcagca aggtaacaac tagtactttt
    34561 ttaatatctt tcgtttttct tgtcagcaat tcatcaaatt tctgatactt ttttggcgat
    34621 aaaataagct ggacaaaggc tacgccatag taacggacaa gcaaaaatcc gattgcttcc
    34681 ccaatcacta ggccaataca actatataaa agcccaaatc cattgccaaa catcagcatg
    34741 cccgctactg aggagatccc tcccggcaaa ataggaatga tcacttggat cacttgcaac
    34801 agaacaaata tcatcactgc atacttgcca aattgctgga taaacgcttg caaagacgtg
    34861 ctcgatcgaa aaatcccatg atgataagca taaagaatca acacaaagaa aaaaaacaga
    34921 ccaataatgg gcatgatctg aagacatttt tgtaaaactg atcctttttt agacatctat
    34981 attccccaca tcttttttca tttattaaaa ctgcctcc
//
LOCUS       DAFEIE010000028        34522 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFEIE010000028
VERSION     DAFEIE010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.028"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(133..306)
                     /locus_tag="LP345_001456"
     CDS             complement(133..306)
                     /locus_tag="LP345_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1760242.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            754..3116
                     /locus_tag="LP345_001457"
                     /pseudo
     CDS             754..3116
                     /locus_tag="LP345_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            3484..4407
                     /gene="truB"
                     /locus_tag="LP345_001458"
     CDS             3484..4407
                     /gene="truB"
                     /locus_tag="LP345_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBL1760243.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4411..5352
                     /gene="ribF"
                     /locus_tag="LP345_001459"
     CDS             4411..5352
                     /gene="ribF"
                     /locus_tag="LP345_001459"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBL1760244.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5704..6489
                     /locus_tag="LP345_001460"
     CDS             5704..6489
                     /locus_tag="LP345_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1760245.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6502..7353
                     /locus_tag="LP345_001461"
     CDS             6502..7353
                     /locus_tag="LP345_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBL1760246.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7477..7929)
                     /locus_tag="LP345_001462"
     CDS             complement(7477..7929)
                     /locus_tag="LP345_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760247.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8394..8762)
                     /locus_tag="LP345_001463"
     CDS             complement(8394..8762)
                     /locus_tag="LP345_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBL1760248.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8912..9394
                     /locus_tag="LP345_001464"
     CDS             8912..9394
                     /locus_tag="LP345_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBL1760249.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9431..10441
                     /locus_tag="LP345_001465"
     CDS             9431..10441
                     /locus_tag="LP345_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBL1760250.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(10556..11269)
                     /locus_tag="LP345_001466"
     CDS             complement(10556..11269)
                     /locus_tag="LP345_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760251.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(11459..12049)
                     /locus_tag="LP345_001467"
     CDS             complement(11459..12049)
                     /locus_tag="LP345_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBL1760252.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            12533..12760
                     /locus_tag="LP345_001468"
     CDS             12533..12760
                     /locus_tag="LP345_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBL1760253.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            12776..13942
                     /locus_tag="LP345_001469"
     CDS             12776..13942
                     /locus_tag="LP345_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBL1760254.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            14176..15219
                     /gene="hrcA"
                     /locus_tag="LP345_001470"
     CDS             14176..15219
                     /gene="hrcA"
                     /locus_tag="LP345_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBL1760255.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            15313..15876
                     /gene="grpE"
                     /locus_tag="LP345_001471"
     CDS             15313..15876
                     /gene="grpE"
                     /locus_tag="LP345_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBL1760256.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            15927..17756
                     /gene="dnaK"
                     /locus_tag="LP345_001472"
     CDS             15927..17756
                     /gene="dnaK"
                     /locus_tag="LP345_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBL1760257.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            17907..19073
                     /gene="dnaJ"
                     /locus_tag="LP345_001473"
     CDS             17907..19073
                     /gene="dnaJ"
                     /locus_tag="LP345_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBL1760258.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(19155..19820)
                     /locus_tag="LP345_001474"
     CDS             complement(19155..19820)
                     /locus_tag="LP345_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760259.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            19796..19969
                     /locus_tag="LP345_001475"
     CDS             19796..19969
                     /locus_tag="LP345_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760260.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(20014..20751)
                     /locus_tag="LP345_001476"
     CDS             complement(20014..20751)
                     /locus_tag="LP345_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1760261.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(20753..22255)
                     /locus_tag="LP345_001477"
     CDS             complement(20753..22255)
                     /locus_tag="LP345_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBL1760262.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            22514..24508
                     /gene="uvrB"
                     /locus_tag="LP345_001478"
     CDS             22514..24508
                     /gene="uvrB"
                     /locus_tag="LP345_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBL1760263.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            24518..27334
                     /gene="uvrA"
                     /locus_tag="LP345_001479"
     CDS             24518..27334
                     /gene="uvrA"
                     /locus_tag="LP345_001479"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBL1760264.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            27597..28862
                     /locus_tag="LP345_001480"
     CDS             27597..28862
                     /locus_tag="LP345_001480"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBL1760265.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            28866..29597
                     /locus_tag="LP345_001481"
     CDS             28866..29597
                     /locus_tag="LP345_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBL1760266.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            29732..30616
                     /gene="rapZ"
                     /locus_tag="LP345_001482"
     CDS             29732..30616
                     /gene="rapZ"
                     /locus_tag="LP345_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBL1760267.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPEF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            30613..31611
                     /locus_tag="LP345_001483"
     CDS             30613..31611
                     /locus_tag="LP345_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBL1760268.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            31645..32580
                     /gene="whiA"
                     /locus_tag="LP345_001484"
     CDS             31645..32580
                     /gene="whiA"
                     /locus_tag="LP345_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBL1760269.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            33123..33773
                     /locus_tag="LP345_001485"
     CDS             33123..33773
                     /locus_tag="LP345_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760270.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            33960..>34522
                     /locus_tag="LP345_001486"
     CDS             33960..>34522
                     /locus_tag="LP345_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBL1760271.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        11453 a         5832 c         7324 g         9913 t
ORIGIN      
        1 aaatcagggg ttgcgggatt tttttgtttt cattaagacg tattacctaa gagttccatg
       61 actttagtct tgcggcgtgt cagctaacca aaaaagagaa aaagaaaagt aaaaaattcg
      121 actttctttt ttctagtagt atataaattt ttgcatatag ataaagatca agataccgat
      181 aacggaagct agattgtaat ctattttagt gacagtcagg tatagccaag taactagaag
      241 atcagtggaa cctgcaccat aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa
      301 aatcacgttg aagttattga tatttccgat tacgccgctt cgatttggtc acgatccaaa
      361 ttttggataa tccctgtaga aattagcata gtagctggga taccaattca catattgaca
      421 aagataacag agacttttac ataaaacgga tcaatcagga aaggaattgc tcgatccagc
      481 cccagttttc cagcaatgtg ttaactggcc cagcgtcatt cagcaaatta tgcatgatga
      541 ggagcgaaat gaactgcgga acagccattg tgataacgac aagttttttg gatcaatgta
      601 aaaaacgtca gcgaaaggaa aaatttcgtg gttttttata cctgttcatt tggctagata
      661 taaaatccaa acaaatgaac agaagtgctt attaggtttc aattgggagt atctgcgcta
      721 gaataagagt aataatgaaa aggagtgtta tgtatggatt attctagtaa agaatacttt
      781 gataaaatga cggcttggtg gcgtgctgct aattatcttt ctgttgggca actttatctt
      841 aaagataacc ccttactgag acgtacactg aaacccgaag atgtcaaaaa acatccaatc
      901 ggtcattggg gaacgattcc tggccaaaat tttatttatg tccatttgaa ccgagtcatc
      961 aataaatatg atttgaacat gttttatatt gaagggccag gacacggcgg acaagtcatg
     1021 gtatcgaatg cttatttaga tggaagttac acagagatct atccagaagt aacggaagat
     1081 gagacaggaa tgcaaaaatt attcaaacga ttttcatttc ctggaggcat tgcttctcat
     1141 gcagcaccag aaacaccagg ttctatccat gaaggcggag agcttggata ctctctttca
     1201 catgcagtcg gagctgtatt agacaatcct gaagtaatct ctgctgtcgt gattggtgat
     1261 ggtgaagcag aaaccggtcc tttagctgga agctggttct caaatgtctt tatcaatcca
     1321 gtgatagatg gagctgtttt accgatcctt catttaaatg gtgcaaaaat agccaaccca
     1381 acgatcttgg cacgtaaatc agatggagaa ttagcaaatt actttaacgg acttggctgg
     1441 gaacctttct ttattgaagg aaatgattca gaaaaattaa atcctgttat ggctgaaaaa
     1501 atggatcaag caatcgagaa aattaaatcc atccaaaaag aagctcgcct gaagacagca
     1561 acagatgtcg tgatgccaaa atggccagta ttgatcgtac gcacaccaaa aggatggacc
     1621 ggtccaaaag aatgggacgg ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg
     1681 attcctgtag atcaagaaca tatggatcat gcagatgctt tactccgttg gctgaaatcc
     1741 tatgaaccag aaaaattatt tgatgcacaa ggacgtattt tagaagaaat cagagaaatc
     1801 gcgcctactg gtgaccaaag aatggcaaaa aatcctatca ccaatggtgg aatcgatcca
     1861 agaccgctta ttatgccaga ttggaaaaaa tatactttgc aatttgaaaa accaggctcc
     1921 gttaaagcag aagatatgac cgaacttggt aaattcgttc gcgagatcat tgagaaaaat
     1981 ccagaaaatt tccgtatatt tggaccagat gaaacaaaat caaaccgatt gaatcaagtt
     2041 ttcaaaacga caaatcgcca atggatggaa aaaatcgaac cagaaaatga tgaatggctt
     2101 tcgccatctg gtcgcgtcat cgacagtcaa ttatcggaac accaagatga agggttctta
     2161 gaagggtacg ttctgactgg acggcatggt tttttgcaag ttacgaatca ttcttgcgag
     2221 tggttgactc tatgttgact cagcacttca aatggatgcg gaaatcacat gacctttctt
     2281 ggcgaaatga ttatccttcg ctaaatctca ttgcaagctc aacagtcttc cagcaagatc
     2341 acaatggata tagccaccaa gatccaggaa tattgacaca tttggcagaa aagaaggcgg
     2401 agttcatccg tgaatatctg cctgcggatg caaatacatt gctcgcagtc atggataaag
     2461 cattccgctc gtcagaaaaa atcaatttga tcatctcttc caaacatccg cgtgctcaat
     2521 tttactcagc agaagaagca gccgtcttag tgaatgaagg cttgaaaatc attgattggg
     2581 cttcgacagc aaaagaggag gaacctgaat tggtcattgc tgctgcagga acggaatcta
     2641 acttagaagc attagcagct gtaactttgc tgctggaaga attcccaaaa ctaaaaattc
     2701 ggttcatcaa tgtcgtagat ttattgaaat tacgtcatcc aagtcaagat ccgcgtgggt
     2761 tgagcgatga agaatttgat caatatttta caaaagacaa accgatctta tttgctttcc
     2821 acggttatga aacattggtc cgcacgattt tctttgatcg tcataaccat catttaatga
     2881 ttcatggcta caaagaaaat ggagatatca cgacaccatt tgacatgcgt gtagtaaatg
     2941 aacttgatcg ttatcatttg gcaaaagacg cagctttaaa aatcaaagga agtcaagcag
     3001 aagattttgc gaaaaaaatg gatcagaaat tacaagaaca tcaaaactat attcgtgaaa
     3061 atggtattga tctgccagaa gtattggatt ggaaatggaa aaatcttgac caataaaatg
     3121 ataaaatcga tcccgcaaaa tagaattttt tacattgatt aagaaactga aaaaataaat
     3181 aaaaaaaacg gaaaaaagac tggaagaatg gccagtcttt tttttcgttt ttgggaagtg
     3241 aaaaccaaac tatttacctg taagccaccc ataaatccaa tcaaatggtg caaagaaaaa
     3301 atcttccatt ctattccctc ctttaaaaaa gcataacatg atttctattt acgtgagcat
     3361 gaattttgtt acgtttttat tgccgaaaaa taaaaaccgt tcattatgat gtcaaattcg
     3421 tcagtaattg atgcaatgtg ttataataat tcagttaaat caaaaatgaa atggagaaaa
     3481 gacatggacg ggttattacc tttatggaaa gaacgcggaa tgacaagtca tgattgcgta
     3541 ttcaaattaa gaaaaatctt acatacgaaa aaaatcggac atgggggtac gcttgaccca
     3601 gacgtagacg gtgtgttgcc catttgtatt ggaaaagcca caaaagttat cgaatatttg
     3661 acagattctg ggaaaatcta tgtaggcgag ataactctag gtttcagtac aacgacggaa
     3721 gatcgatccg gagaacgggt agaaacaaaa ccagtagata tgtctttatc tgaaaaaaaa
     3781 atagatgaag tgatggcttc atttattggt gagatcaccc agataccacc aatgtactca
     3841 gcggtaaaag tcaacggtaa gcggttatat gaatatgccc gcaataatga aacagtggag
     3901 cgtcctgtta gaaaggctca gatttaccgt tttatccgga caagtgaatt gacaagagac
     3961 gaagtgacag gaaccatttc ttggcgcttc gaagtagaat gcgggaaagg aacctatgtc
     4021 cgcacattag ctgtagatac aggcaagaaa cttggttacc ctgcgcacat gtctgatctg
     4081 acccgaacag caagtgccgg tatgtcccag aaggatgctc tgacattaga agaagtagct
     4141 caagctgtga aaaatgggac aatcgatgat tgtttgctgc caatagaaaa aggagtggaa
     4201 cggttcaaac gagtagatat tactgatgaa gtatggcaga aagtaaaaaa cggtatgaga
     4261 cttgattata ctgtatttgc gctcccagaa atgccgtcag aagaaattgc tttgttttat
     4321 aaaggaaaag ttgtcagtat ttatcagcca aacccgaaag aaaaaaacaa attaaaacct
     4381 agtaaagtat tgagaaatga ggaataacga atgaatatca tcaagatcag acatccttac
     4441 caatcagaac aaattccaga agacgatgtc gttttagtgc tgggattttt cgacggcgtg
     4501 catatcggac accagaaagt cataaagaca ggtatggaaa ttgcacaaaa agaaggattg
     4561 aaattagcat tgatgacttt caatcagcat ccatctattg tctttaaaaa gatcgatcct
     4621 agcagcgtga aatatttgac tagccttaag caaaaagaag aaaaaatggc cgctttgggt
     4681 atagattatt tatatgaagt tgattttact tcttcttttg ctcatttagc accgcaggaa
     4741 tttgttgatc aatacatcgt agggttacat gcaaaatatg ctgtttccgg ttttgattat
     4801 acgtatggac caaaagacat tgcagatgtc gctcattttc ctgaatatgc caaaggaaga
     4861 ttcaaaatcg tcacagtttc taaagaagaa gaacaaggtg aaaaaatcag ctctacccgt
     4921 attcgtggat tactagacag cggacaagta aaagaagcag caaaactatt aggttgcaca
     4981 tatgaggtag aaggggtagt tgtccatggc gatgcacgag gcagactact aggattccct
     5041 acagcaaatg tcaaagtaaa gagcacggtt catttgccta aagaaggtgt ttatgtgtcg
     5101 gaaataaaaa ttggggaaac atggtatcca gccatgggtt caattggaca taatgataca
     5161 ttcggtgaag gacgggagct gactgtagag ttgtatattt tggactttaa tcaagatatc
     5221 tatggtgaac atgtcgcggt acgctggaat caatttttaa gagatcaagt gaaattttct
     5281 agtgtagagg aattgattga acaactcaag gaggatgaac aagcaacagc tgaatatttt
     5341 tctcagcaat aaaacattat gcataaaatc tcttgtttat gtataactag caattacaat
     5401 aaaatgggtg ataaataagc ccaggaaagg ggctgtgaca aaagtcttgt cacagccttt
     5461 ttttccaaat aaatggtttt tcagaagtag cttcttcgga aataagccga aatttcttga
     5521 agctgaccac ttctgtcaca acctctttct ttatagaaat aaaaggacac tagcaattca
     5581 tgaaaacgat tgctagagcg tatcatttgc tttagactat atatcttggt gtacactcac
     5641 tttaaggcgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa aggagtgggt
     5701 actatgtaca aggaattaga aaacaaagtc gcagtagtaa ctggtggctc aaaggggatt
     5761 ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt caactataac
     5821 tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg cggaaaagca
     5881 gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact tgatacggct
     5941 ttagaaaatt ttgggacact ggacgtttgg gttaataatg ctgggatgga aaatcagcat
     6001 ccaacccatg aacttagcct tgaagattgg gaaagagtgt taaaagtcaa tttgactggc
     6061 gtttttatcg gaacgaaagc ggctttaaat tactttacag agaataataa aaaaggaaat
     6121 atcatcaata tgtcttctgt tcatgaacag atcccatggc caacgtttgc tcattacgct
     6181 gcttcaaaag gcggggtaaa attatttacc gaaacggtag caatggagta tgcaccgaag
     6241 ggaatcagaa tcaatagtat aggccctggt gctatccgta cacctattaa tgcggcaaaa
     6301 tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg acgcgtaggt
     6361 gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc cagttatgtt
     6421 acaggtatta cactatttgc agatggtggg atgactttat atccttcttt ccaaggtgga
     6481 aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc agttggctgg
     6541 gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga gatattagga
     6601 actggtattg gagcggtgct tgtcggctta ctcgttcaat tattcgcttc tccagctggt
     6661 atttcagtga ctacattttt gattagttta ctttctggtg cattttgggt tattggacaa
     6721 acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc aatttcgact
     6781 gcattacagt tagtcggaac ctcgttgatt ggtgtcttcg cttttggaga atggtctgga
     6841 agtatgggga aaatcattgg agcagcagca atcattcttc ttgtatttgg ttctgcttta
     6901 acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat tagtctatta
     6961 gcatcaacaa gtattggtta ttgggtatac agtgcattgc ctaaactagt tgatgcaagc
     7021 ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt gatttatgtg
     7081 attttccgta aaccaaccgc attttctgaa gacaagagtt ggaaagcaac gatcgttgga
     7141 gccatcttta gtgtgtcagc attggcttat attttttcag caaatgaaaa tggggttgct
     7201 actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg tatgtacatc
     7261 ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt attgctgatc
     7321 gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa tttcatttat
     7381 taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc gctagaattt
     7441 ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaaggg aaatatctgt
     7501 ctggatcaat aatttttcat tgatccattg actaaagttt acgacataat tgaagttacc
     7561 accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa gacggtcttt
     7621 tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggaatt gattgattgc
     7681 tgtaaaatca cgatattgaa ggttgaaacg catcgtgatt ggtgcattta gcatgaatcg
     7741 ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa aaagattacg
     7801 ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt catgaagata
     7861 atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta ctgagtaaaa
     7921 atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga tatttgctta
     7981 atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca agtcagaaaa
     8041 ttctaacttt tatttctcta aagaaattcg ttctctccta aagtgatatt atatttaaat
     8101 atacctgaaa ataatgggca gtattatgaa agatcactga tattttctcg tattttttcc
     8161 ttattcaaaa gttttgcagg aaaattgctg aaaaaataat tttactaagt agaaaattca
     8221 aagccattca atcagtgatt tttttcagca caagaaagac tccttataaa aatagcagat
     8281 actttgtcaa ttaagtgttt aaccagggat gataaaaagg ataggattga acaaaacctg
     8341 tataaggtga tgaatagttt cctcgccagt aaaaggttta ttcgtataaa gctttatcgc
     8401 caaaatttat catgaccttt tttatcttca atattaaatg aaatcaattg ttcaatcaat
     8461 tcccagttga ttacactttt ccaaggaact ttgatgacgt tatccgtata tacgtagcct
     8521 gcttcttgga tatttttttc aagggcacga atcgctgctt tttccggtgc gatagaaaaa
     8581 tgatttttag caaaactaaa tgcaataata aaggtaccat ggtcagtaaa cataggttgg
     8641 ttccatttta cagttgtgtc tagctgggga tacgtttctg ttatcttagc aaaaaggtct
     8701 ttgatctttt gttgatgttc tttttctttg atttgattga tgatcggctg aaatttttcc
     8761 attctaaaac gcctccatta agtggtttga tttattttac cagaaaaaca atagttatgt
     8821 ataaaaaacg aacaaaacac aagtaatgtt gtaaccgcta tatttatatg ataagatgtc
     8881 tcaaataata aaatagaaaa gagacataaa aatgattgac ttggcaaaga aattcttaca
     8941 cgaaaatata tattttgagt tgtatcatca tcgagccatt tatacaaatg aagatgcttt
     9001 ggtaataaag aaagaacaag gatttacagg tacagagacc aaaagcttat tcttaaaaga
     9061 taaaaaagat aataactacg tatatctgac ttttactacg aaacaaacgg atttcaaagc
     9121 attagggaag atcgtcggta aaaggctttc tattgtttca tcagaacgca tggaagaaca
     9181 aacgggacaa aagcagggcg ctgtttctcc gtttggttat gaaaaacaga ttccgattat
     9241 tattgatgaa gagctcttat caaatgaaaa acttgttttt gcaccaggta gaccagatca
     9301 aacgatggtc atccaaacgg ttgacttaaa caaaatcatc cagctacttg agatgccgat
     9361 atttttgatg ccggcaaacg aaaaaaacaa ttaaccaagt aaaatagtgc atacttggag
     9421 gtgaagcaac atgataagtt atccattatt agaaagaaat gcaacgattg gggttactgc
     9481 accatcctca ggcgtatcag aggaacacca ttcgttactc gaatcagctt taaagagaat
     9541 ggaagaaaaa tctttccaag tagttactgg aaagacgctt tggacgcaag ataaggaaaa
     9601 atcaggtcca gcaagaaaac gagcagatga attcaatcaa atgatgcaag atgaaaatat
     9661 ccaaatgatc tttccgactt ggggaggaga attattgatt gagattctcg attttgtcga
     9721 ttttgatgct ctacaaccaa aatggatagt aggttattca gatattagta cgttgctact
     9781 tgctgtcaca ttaaaaacag ggatagccac tgcacatgga actaacctta ttgatttaag
     9841 aggagagtac ttggatgaaa cgacagcaat gtgggaaagt gtactgaaaa caagagaagg
     9901 agaatcgatt ctacagcaat cttctgaaaa gtatcaaaaa gtgtggcccc atgagcattc
     9961 atcatcttct gttttccatc tcactgaacc aacaaattgg caatcagtca gcggagatgc
    10021 agtaaggatg aagggacgat tattaggtgg ttgtattgat acgatcaggc atttaatcgg
    10081 tactccttat ggagatgtcc aatcttttaa aagaaagtat aatgatggaa agccgatctt
    10141 gtggtttcta gaaaactgtg agctatcgtc agttgattta agaagatcac ttgttcagat
    10201 gaaactggca ggctggtttg atggcagctc ggggatcatg ttcggtagaa gtgcggcaga
    10261 ggatttgtta gattataaaa tgaaggatgt atacgaagat ctgtcaaagg aattaaaact
    10321 accgatcttg tatgatattg attgtggtca tgtaccgcca caactgacat tgattaatgg
    10381 tgcctatgca gaagtagcgg tagaagatag aaaagcgact gttttgcaaa cgtttattta
    10441 aaaaattttt tcctgccttg gagtctatca aagaccaata aatctaaata gaaaagaaag
    10501 tgaaagaagc tgacaaaatg ctgtcagctt ctttttgtat aacatattag aaagtctaat
    10561 tatctataac tgtcacatcg attaactgtt tcacgtcatt gggatttcct gtaggaatag
    10621 ctactacaga tgcattatca atgatttctt gagttgtttc tctaatgaac gctggataag
    10681 atgtttgatc tgcaggcatt tgccaatgtg aaggaactgg ataactagtg attgtcccgt
    10741 catggttact tgaatacact aaaactccct ggtaactgta tttcccagtg agcataacca
    10801 catctttcgg atagactgca ctccctgcat cataaggggc gataggtgtt cctgcaggat
    10861 aatgaataac atgtaattcg aaatcacccg atgtatctct aaaagtatta cctctaatag
    10921 ctagccaaac acgtgcgtac tcaatttgta gatcagaata tcctgctaac ggatctattg
    10981 actgagaaga ctgtgaggag gttgtgtcta ttgttgaaga agaaatattt gtctcaactg
    11041 tactactaga tgtagaagaa gtattgggct ctgagacttt actgcttgtt gaagatgtat
    11101 tcgtttcagt agaagctgat ttctgagtac ttgatttttc agctgaactg gtttgtctga
    11161 ttgaactttt gtctgtggtc gcagatggat cactattttc tttactagga gacgtacatc
    11221 ctacaaggaa taaagagacc aacaataaaa taaaacctaa ctttttcata taaaatacct
    11281 cattattttt ttaataccag tatagcataa tcctgaattt ttgaatccgt aaaaccttgt
    11341 ctatgaatat aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa
    11401 tcatcagtaa aattacttgt cacactattg ataaggagta tttaattgaa gagaatgatt
    11461 aggagaaagg atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa
    11521 tcgttttttc tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga
    11581 attctatagg agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt
    11641 ctataaaatc ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc
    11701 cggtgtgttt gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa
    11761 tagcagctac tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat
    11821 tttttatgtc ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt
    11881 gttcgattaa gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga
    11941 tagaagcagt tttgttttgc catttctcat tttggtttag tgtgctagta atataagcac
    12001 cttcccaatc ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct
    12061 cctttactat ctataacaag gacaacagtt ttaacctaca gacattcatt aaaattgggt
    12121 agcgacagcg aaaacaacaa ttcttaagtt ttagacagag tatacagata gtcaacttaa
    12181 ttaaatacga actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat
    12241 tttgcataca tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tattaaaaga
    12301 aactggaagg caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca
    12361 tgaaaacaac cctagagata tataactagg taaccagttt aatgaaagaa aaaatcatcc
    12421 aagaagtcga ttcttggatt ttttagtgga tttgttcgcc aaatacgttt agtatgcgta
    12481 tatgagaggt tgtaagcaaa gcgttgtggt ctgagcactt aaggaggaat ctgtgaaaat
    12541 agcttttcat atttttgcag attttgactt aatgccgaag gtcagctttg cgattaccgt
    12601 ttatcgagag gctgtaaaag caccgtgtag ctccgatgac aataagcaag catttttaga
    12661 gctaggtttc cttgattcta aatatgcggc ttatttcaat gagttggtgc ttgaacgcga
    12721 ttttaagaag gtcgaaaaca ggcacgactt ttcgacgtaa ggagaaagaa tttcaatgat
    12781 agaaacaata aatcccgcag aaaacaaggt ttctgcgtac attcatatcc cattttgcga
    12841 gcatatctgc tattactgtg attttaataa agttttttta gaagggcagc cagtagatga
    12901 gtatgtggaa atgctgctga atgaaatgaa aataatgcta gaaagtcatc cgacagcgaa
    12961 tttagaaaca ctttacgtag ggggcgggac accaacttct ttatctgcta aacaacttga
    13021 tcgactgtta tcaggtgcta gagagatcct gccttttcaa aatggtaatg agtttactgt
    13081 agaagcgaat ccaggtgatt tgacccgtga aaaacttcaa gtaatgaaaa actatggcgt
    13141 caatcgttta tccatgggag tgcagacatt tgataatcgc ttattgaaaa aaattggacg
    13201 taaacacacc gcagaagatg tgtatcaaac tatgcaattt ttagaagcag aaaattttac
    13261 caatgtaagc atcgatttga tttatgcatt accgggacaa acactagaag gatatctgga
    13321 tactttggaa aaagctttgg ctttggatct gcctcactat tctttgtact cattgatcct
    13381 cgaaaacaaa acaatgttca tgaactgggt acgacaagga agactcgaac tgcctgatca
    13441 ggaaacggaa accagaatgt ttgaagagac gattgaagca atggaaaagc atggacgtca
    13501 ccaatatgaa ataagtaact ttgggctctc cggacatgaa tctcaacata acctcatgta
    13561 ctggaacaat gaccactatt ttgggtttgg agctggtgct agcggttatc ttggagatat
    13621 tcgttaccgc aacaaaggac caatccaaca ctatttacgc ccattacgag caaatgaacg
    13681 cccggtattg gaagaagaaa aattgacacg aaaaaatcaa atagaagaag aaatgttctt
    13741 aggactaaga aaaaaaacag ggattactaa aaaacatttc tatgatcgct atcaaaaaac
    13801 aattgaatcg gtgtacggtg atgtgctaag ggaattagag caagaagggt tacttgttaa
    13861 tgaagaagac cgtgtttatt tgacaccaag agggaccttt ttggggaaca atgtgtttga
    13921 gcgctttttg tttgaaaaat agtttaaaga atatttgttt tttatctgaa tttaaataaa
    13981 aaaagttcaa aaatacaata aaggactatt gaaacgttga tataactgga tttacatcaa
    14041 ttatttagaa ttagcactct tgtgtttaga gtgctaaaaa atggagtctt tctcttgaca
    14101 ggagaagggc ttcttgctat atttataagt ggattagcac ttagaatata tgagtgctaa
    14161 tgagaggtga ggaagatgtt aacaaagcga caaaacgaca ttttacgtct gatcatccaa
    14221 cactatacga gtagtggcgt gcccgttggt tccaaaacat tgatgtctga gggagtcaag
    14281 gccagctcag caacgattcg caatgatatg aaagcattag aagatgaagg attgctgttg
    14341 aagactcact cttcttctgg gcggattcca tctgctttag gctatcgtta ttacgtggat
    14401 catttgttaa aacctgctcg cgtagcagaa gatgatttgc tgctgattcg tcagtctcta
    14461 ggcagagaat ttcatgaaat caatgagatt attaagcaat ctgctgagat attatctgag
    14521 ctgacaagct atacgacttt ttcattggga cctgaaataa aagaccgccg actgactggc
    14581 tttcgtatcg tacccttgaa taatcgacag attattgcta tcgtcgtaac agatatgggg
    14641 aatgtagaaa gccaagtgtt cactcttccc gaatatatgg gaagtcagga actagaaaaa
    14701 atggtacaga ttgtaaacga ccgtctagtc ggagatcctc tgatgacggt gtaccataaa
    14761 cttcgtacgg agattccgat gattcttcat aaatatttcc aaacgacaga agggatgtct
    14821 cagttatttg acaccgttct tggtcatgtt tttgaagata aggtttatgt cagtggacaa
    14881 atgaatctct tggattatga gccccgtcaa gatcttgatc agttcaaatc gatgttttct
    14941 tttatgaaag actcagacgg acttacacaa atgatcactc cgatggatag caatattcat
    15001 atcaagattg gtgctgaatt aggcaatgat ttattgcaga atatgagtat gattcaagca
    15061 agttacgaga tagatggtca tggaagaggt acaatagcct tgttagggcc tactagtatg
    15121 ccttattctc ggatgttcgg tctagtcgat gtttatcgaa gagaactagc agctaaactt
    15181 gctgattact accgttcgct tgacttgtca aactcgtaat gtgaataacg aagctatttg
    15241 cagctgatcg ttctctcttt cttagtaaga gcaatcaaac agctgactga ataatgaaag
    15301 gaagactgta tcgtgaaaga aaatcaagaa gaactagata aagaaatgac agatgctcag
    15361 ccagaaccgg aaatcgatgt cgaagctgca gaagattcgg gtatttcaga agctgaagcg
    15421 gaagaattcg aaacagcgaa attaaaagct gagttagaag aaatggaaga taaatacttg
    15481 cgggctcgtg ctgaaatcgc aaatatggca aatcgaggaa aaaatgagcg tgagcaatta
    15541 caaaaatacc gttcacaaga tttagccaaa aaattacttc catcaattga caacctggaa
    15601 cgtgcattag ccacagaagt gtcagatgat caaggggcag gtttgaaaaa aggcgtggaa
    15661 atggtcttgg aaagtttgcg taacgcactg gaagaagaag gaattgaaaa aatccctgct
    15721 aaaggagaag cctttgatcc taatcttcat caagcagtac aaactgttcc agcgactgaa
    15781 gatacaccag ccgatacgat tgtagaagta ctacaagaag gctacaaatt acatgatcgc
    15841 gtgttaagac caaccatggt cattgttgca caataattgt gcggatataa aacttacact
    15901 ttcaattaaa gaaggagacg ttaattatga gtaaaattat cggtattgac ttaggtacga
    15961 ctaactctgc agtagcagta ttggaaggaa acgaagcaaa aatcatcgct aacccagaag
    16021 gaaaccgtac aacaccttct gttgtatcat tcaaaaatgg agaaatccaa gtaggggaag
    16081 ttgcaaaacg tcaagctgtg acaaacccaa atacgatttc atcaatcaaa cgccatatcg
    16141 gtgaagcagg ttacaaagta gatgtagaag gtaaatcata tacaccacaa gaaatctcag
    16201 caatgatcct tcaatatatc aaaggattcg cagaagacta tttaggtgaa aaagtcgaaa
    16261 aagcagttat cactgtgcca gcttacttta atgatgcaca acgtcaagca acaaaagatg
    16321 ctggtaagat cgctggtcta gaagtagaac gtatcgtcaa tgaaccaact gcagctgctc
    16381 ttgcctatgg tttagataaa acagatcgcg acgaaaaaat cttagtattc gaccttggtg
    16441 gcggtacttt tgacgtatct atccttgaac taggagacgg tgtctttgat gtattgtcaa
    16501 cagctggcga caaccatcta ggtggggacg actttgataa caaaatcatc gactacatgg
    16561 tagcagaatt caaaaaagaa aacagcattg acttgtctca agacaaaatg gctttacaac
    16621 gcttgaaaga cgctgctgaa aaagcgaaaa aagatttatc tggcgtatca agcacacaaa
    16681 tcagcttgcc atttatcaca gcaggagaat ctggaccatt gcatttggaa atgacattga
    16741 cacgtgcaaa atttgatgaa ttaacagctg acttagtaga acgtacaaaa gtaccagtac
    16801 gtcaagcgct aaaagatgca ggtttatcac aatcagaaat cgacgaagtt attttagtcg
    16861 gtggatctac tcgtatccct gcagttgtag aagcagtacg taaagaaaca ggaaaagaac
    16921 caaacaaatc agttaaccct gatgaagtag ttgctatggg tgctgctatc caaggtggcg
    16981 tgatcactgg tgatgtgaaa gatgttgttt tacttgacgt tacaccattg tcattaggta
    17041 tcgaaacaat gggtggagtg ttcactaaat tgattgaccg caatacaacg attccaacaa
    17101 gtaaatcaca agtattctca actgcggcag ataatcaacc agcagtagac atccatgtat
    17161 tacaaggtga acgcccaatg gctgctgaca acaaaactct aggaagattc caattgacag
    17221 atattccagc agctcctcgt ggtattccac aaatcgaagt aacattcgat attgataaaa
    17281 acgggattgt aaatgtatct gcgaaagatc taggtacaca aaaagaacaa aaaatcacga
    17341 tcaaatcttc ttcaggtcta acagacgaag aaatcgaacg tatggtaaaa gatgcagaag
    17401 caaatgcaga agcagataaa gctcgtaaag aggaagttga cctacgtaat gatgtagatg
    17461 cattgctatt ctctgtggac aaaacattga aagaattaga aggcaaagtg gacgaagaag
    17521 aagtgaaaaa agcagaaaca gctcgcgatg aattgaaagc cgctgttgaa gcaaacaaca
    17581 tcgaagaaat gaaaactaaa cgcgatgcat tgaacgaaat cgttcaaaac ttgactgtta
    17641 aactatacga acaagcggca caacaacaag ctcaagaaaa cccagaagca gctcaaggcg
    17701 gagcagatga tgtcgttgat gctgattttg aagaagtcga tggcgacgat aaataatcag
    17761 ttcactgaat ttcgagagaa ggccaaagtt gctactttgg ctttttcttt tgaaaaatag
    17821 tttgaagtat cggtttttgt ttcaaacaaa atatgatatg ataacaagcg acgtgaaaat
    17881 gatgagaacc aataggagga aagcctatgg caacaaaacg tgattattat gaagtcttag
    17941 ggctctcaaa aggagcatca gaagatgaaa taaagaaagc ttatcgtaag ctttcgaaaa
    18001 aataccatcc tgacatcaat aaagaacctg atgcggaaga aaaattcaaa gaagtatcag
    18061 aagcatatga gattttaagt gacccgcaaa aacgcgctgc atatgaccaa tacgggcatg
    18121 caggcacaga tccaaattac ggtgctggtg gagctggtgg cggatttggt ggattcggcg
    18181 gcttctctgg tggcggcttc ggtggttttg aagatatctt cgactctttc tttggaggag
    18241 gcggtcggtc agtcgatcca aatgcgcctc gtcaaggtgc tgatttgcaa tatacggtcg
    18301 acttgtcttt tgaagaagcg atttttggtg tagaaaaaga aatcaagtat aatcgggaag
    18361 aaatctgtca tacttgtggt gggaacggtg caaaaccagg cacacaacca actacttgtc
    18421 ataaatgtca tggtgcaggt acgattaatg tagaacgcca aacaccactt ggacgagtga
    18481 tgagccgtca aacttgtgat gtttgtcatg ggacagggaa agaaatcaaa gaaccttgtc
    18541 caacctgtca tggctcagga catgagaaga aagcacattc agttaaagtg aatgtaccag
    18601 ctggtgtaga agaaggacaa caaatgcgtt tagctggtca aggagaagct ggagaaaacg
    18661 gcggaccatt tggtgatttg tatgtggtct tccgtgtaga agaaagtgat atctttgatc
    18721 gtgaaggttc tgaaatttac tatgaattgc ctttaagttt tgtacaagca gctttggggg
    18781 atgaagtcca agtaccaact gtccatggag atgtgaaatt gaagatccct gctggaacac
    18841 agacaggtac gaacttccgt ttacgtggaa aaggcgctcc gaagttacgt ggtggtgcaa
    18901 caggcgacca acatgtcaaa gtaaaactga tcacaccgaa aaatctaaat gaacaacaaa
    18961 gagaagcatt acgtgcattc gctgaagctg gcggcatcaa agttgaagaa cagcaagaag
    19021 acggtttctt cgataagttt aaagatgctt ttggcgggaa aaagcggaag tagtttttct
    19081 agtaaaaacg ctaagtcatt aataattaaa aaccagacga acaatcatat gttcgcctgg
    19141 tttttttgta gttgtcatgt ttgtaccaac aaaaaagcca gctttagaat atgataatcg
    19201 tcatagtttc taggggtata accagtgaga gaatggaact tgttcaatcg atattgcaag
    19261 gtgtttttat gaataaataa ttcttctgag caatttttga tgcttccgtt atttttactg
    19321 aagcatgcca aagtcttctt gaacaaatgt acttcttctt ctgtcaggct tttcaaaata
    19381 cgttttacat ataatgttcg ttgatctgac gggattgctg gtaaaacgat cccgaggtct
    19441 aaatcttcaa aaaagcggat ctcgttcaca gattgatgga aagctatcca ttcgcaaact
    19501 tgtttggcat gaaggaaaga ttgcggtgtc tcttgctctg tataacaaag cgacccaatt
    19561 ccaaagttta gctgtaactg atacatttta ttaaactttg tctggatttt atcaagcaat
    19621 gatagcaatg aggctctgga aatccgattg actaggataa tgatttgttg tctatgtaca
    19681 gtgagcaaag cctgtccgta ataagagaag accctttcga gcaactccaa taaaggattg
    19741 atccgttctt gacacaattg ctgattgtca gaaagttgtc ccacaactac ataatatgga
    19801 gaagaaaaat caagctcaat taagtgaggg tggtatcgac tatgtacttg atatcatcaa
    19861 tgaaccgatg gtactttctt atgcgatgga acaggtagag cgattgcttg tttgtgcagg
    19921 aaaacaagcg atgcggctga tacgattagg tgagaaaata agaagataaa aatacacggt
    19981 cccttcatgg cgaccgtgca tttttggttt ttattaaata tttaatactt tattcaagaa
    20041 atcttttgtc cgttcatttt gcggattttc aaagatttgt tgaggcgttc catcttctaa
    20101 aaagtttccg tcgtcaatga acatgacgcg attggccact tctttagcga accccatttc
    20161 gtgcgtaacg ataaccatcg tcataccttg ttctgctaac tttttcatga cgttcaagac
    20221 atcaccgacc atttcaggat cgagtgcaga agtaggctca tcaaaaagca tgatgtcagg
    20281 gttcatcgct agagcacgag caatagccac acgctgtttt tgtccaccag aaagcatttc
    20341 aggatacata tcttttttat cttctagacc aactgtctgc agtaatttga ttgctttttt
    20401 ctctgcttct tctctagatt ctttcttcag gtccatcggt gctaaaatga tgttttccaa
    20461 aatagaaaga tgagggaata ggttaaagtg ttggaatacc attccgatat gttgtctcac
    20521 caagttgata tctgtgcttt tatccatcaa gtgggcgccg tcaataataa tttcaccgtc
    20581 agaaggttct tctaaacgat tcaagcaacg caagaatgta ctttttcctg aacctgaagg
    20641 gccaatgata cagacgacat ctccttcgtt gatggataca ttgatgtcgt ttaatactgt
    20701 gttatcgccg tattttttga ctaaatgctc aactaagatt ttttctgcca tcttacttca
    20761 ccttcttttc taaaactttt gctaattttg tcaatgctgt gatcaaaatc aagtacatga
    20821 tcgcaatgat caagtaaaca tacgtacttt gtgttgtacg tgcaacaatg atcttaccag
    20881 tttgcagcaa ttcgactaca ccgattgcgg aaatgatcgt tgtgtctttt aatgagataa
    20941 cgaactgatt gacgaatgat gggatcatga tgcgtatcgc ttgcggcaaa atgatttttt
    21001 gcattgtccg attataagaa agacctaaac ttctggaagc ttccatttgt ccgacaggaa
    21061 cggcgttgat cccgcctcga acaatctctg cgatataagc acttgcgtta agagtcaagg
    21121 tgataacacc agcaaggaag tcaggaatcg taaatccaac gataccaggc aacccaaaga
    21181 aaataaagaa cgcaagaacc atcattggaa ttcctcggat gatatcgaca taaatactag
    21241 caattgtgcg aagagcgcgt attggtgcta cactgaataa tccaaaaatc acaccgatta
    21301 ctatagccaa agcaaaggag atcaaagtta ggagaattgt tctccaaagt cctttcaaca
    21361 atgcttgata gttgttttgg ataagtccaa gaaatgttga ttcatcagca gtggaagact
    21421 cactggaagt ttctgaacca tccgctacat attctttaat aatcttatcg tattcgcctg
    21481 ttctttttaa ttctttcaat ccttcattga acatattaag aagctcagga ttttgtcctt
    21541 ttttaacggc aaatgcatat tttccgccag attctttttt gatcggtgtt tccaattctt
    21601 gtccttgttt gatcgcataa ccgattaccg gataatcatc catcattgca tcgattgcgc
    21661 caacttttaa cccgtcgtac aattgatcag cagcatcaaa atatttgata gaatagccat
    21721 attcagattc atggtcgctt aaaaattcag cactttcggt accaactttt gctccgactg
    21781 tttttccttt caaatcttca taagacttga tcgaagtatc tccttttttg acagctaatt
    21841 ggatcccgct atcaaagtaa gaatcagaaa aatcatagct tttctttcgt tcatctgtta
    21901 cagtcattcc ggcaatcatt ccgtctgctt gtcctgattc caaagcttgc aaagcagcag
    21961 agaaaccacg gtagtccatt cggatgttaa atccttgcag tttggcgatg ttttccatca
    22021 attttacatc gatgccttcg tactcgccct ttgcgttttg aaattcaaat ggagcaaaag
    22081 cagagtcact ggcaattacg tatacgtctt ttttgggctc tattttttgc attgtctcgc
    22141 ttgtgcttga ctctgccgtt gtagtgttgt cagcttgtgc aacatgacca aacgcaagtg
    22201 tcacaagtcc tgtcattaag aaaacaaatg agtgaaataa atgctttctt ttcataatca
    22261 acctcctaaa tttccaatat tttattatta taggcgaaaa gtgctgaatc agacaagact
    22321 gtaagctcga aaaaatgaaa aaaatgcgag tttctaacat tttatgttat aaaacataac
    22381 atgtataata agataaaaaa gtggcgaaag tatgttcggt gtggtataat tttttagtaa
    22441 ggaatgcctt tgctttcctt ttctttttat tggtcgtaaa atgaaaagga atgaatgaaa
    22501 aggaggacga agaatgattg agagagatac ctcccgacac tttgagcttg tctcgaaata
    22561 ccaaccggct ggtgatcagc ctgaagcgat taaccaatta gtggatggcg tagtcggcgg
    22621 gaaaaaagca caaatcttat taggtgcgac tggaacaggg aaaacatata cgatttccaa
    22681 tcttattgag aaagtgaata aaccaacact gattattgcc cataacaaaa cattggctgg
    22741 tcagctgtac ggggaattca aggaattttt ccctaacaat gctgttgaat attttgtttc
    22801 ttattatgat tattatcagc ctgaagctta tgtgccttca agcgatacgt atatcgaaaa
    22861 agattcaagt gtaaatgatg agatcgacaa attacgacat tcggctacta gttcattatt
    22921 agaaagaaat gatgtgatcg tcattgcatc cgtttcatgt atttttggat taggctcgcc
    22981 ttttgagtac caaaaacaag tagtttcgat tcgacaggga gcagaactag atcgcaatca
    23041 gttgattcgt gacttagtca gtatccaatt cgaaagaaat gatatagatt ttcagcgcgg
    23101 tcgttttcga gtgcgcggtg atgtcgtgga gatttttccg gcttcaagag atgaacgtgc
    23161 cttacgtgtg gagttttttg gagatgaggt cgaacgtatc cgagaagtca atgcactgac
    23221 aggtgaagtt ttaggagaaa cggaacacgt agcaatcttc ccggcgactc actttgtgac
    23281 gaatgatgaa catatggagc atgccgtagc gaatatcaaa gaggaattag aacagcgttt
    23341 aactgtcttg cgaaatgaaa acaaacttct ggaagctcaa cgtttagaac agcgaaccaa
    23401 ttacgatatt gaaatgatgt tagaaatggg ctacacgtcg ggaattgaaa attattctcg
    23461 gcatatggac ggacgtaaag aaggtgaacc gccttatacg ctattggatt tctttcctga
    23521 agattttttg atcgtggcgg acgaatcgca cgtaaccatg cctcaaatca gaggaatgta
    23581 taatggtgac cgagcgagaa aacagatgct agtagattac ggtttccgtt tgccatctgc
    23641 tttagacaat cggccacttc ggttagaaga gtttgaaaaa catgtcaatc agatcattta
    23701 tgtctctgcg acgccaggac catatgaaca tgaacaaaca gataccgtta tccaacaaat
    23761 catccgtccg acagggctgc ttgacccagt gatcgaagtt cgtccaatca tgggacaaat
    23821 cgatgatcta gtaggcgaaa taaatgaacg agtcgaaaaa gaccagcggg tgtttgtaac
    23881 gacattgacg aaaaaaatgg cagaagacct cacagattat ttcaaagaat tagggatcaa
    23941 agtcaaatat ttgcatagtg atatcaaaac gctggaacga acagaaatca ttcgagatct
    24001 tcgattaggt gaatttgatg tgttagttgg aatcaatttg cttcgtgaag gattagacgt
    24061 acctgaagtt tcccttgttg ctatcttgga tgcggataaa gaaggctttt tacgtagtga
    24121 acgttcctta gtccaaacga ttggacgagc tgctcggaat gaagaaggta aagtaatcat
    24181 gtacgcagac aaagtaacag attctatgcg tctagcgatg gatgaaacgt caagacgtcg
    24241 tacgattcag cagaagtaca atgaagaaca tgggatcgtt ccaaaaacga tcattaaaga
    24301 aatccgagat ttgatttcta ttacgaaaga atcggaagat gatacaaaag aagcggtaca
    24361 agtctcgtac gaagaaatga cgaaggaaga aaaagacacg ttattgatga aattagaaaa
    24421 agaaatgaaa gatgcggcaa aagctttgga ttttgaaaca gccgcgaatg tgcgagatat
    24481 gattttagaa ttaaaagctt caaagtagga ggacaacatg gctaacgata aaattacgat
    24541 tcatggtgca cgtgcccata acttgaaaaa tatagatgta acgattccac gagataaatt
    24601 cgtggtcgtt acaggtttgt ccggttctgg aaaaagttcc ctagcatttg atacgctgta
    24661 cgctgaaggg cagcggagat acgtagagag cctttctgct tatgctcgtc agtttttagg
    24721 acaaatggat aagccggacg tagatagcat cgacggattg agtccggcga tttctattga
    24781 tcagaaaaca acaagtaaaa atcctcggtc gacagtaggt actgtgacgg aaatcaatga
    24841 ctatttacgc ttgttgtttg cacgtgtagg acatccgatt tgtcccaacg atcatatcga
    24901 gattaccagt caatcagtag atcaaatggc agatcaagta atggctttgc ctgagcgcac
    24961 aaagatccaa gtgttggcac cgatcgtggt aaagaaaaaa ggacaacata aaaaaatatt
    25021 cgaacgaatc caaaaagagg gatacgtccg cgttcgagtc gatggtgaga tctatgattt
    25081 aagtgaagtg cctgagctgg agaaaaacaa aaaacatgat atcgcgatcg tcatcgaccg
    25141 gatcattgtg aaagaaggga ttcgttctcg cctatttgat tctttagagg cggccctgcg
    25201 attagcagac ggctatgctc tggttgacgt gatcggtgaa gaagaaatgt tgtttagcga
    25261 acactatgcc tgtccttatt gcggatttac tgttggcgaa ctagaaccaa gactgttctc
    25321 attcaatgcg ccttttggag cttgtccaga ctgtgatggt ttaggtgtca aattagaagt
    25381 cgatcaagat ttagtgattc cagatagaac gaagacactt agtcaaggtg ctatcgttcc
    25441 atggaatcca atcagctctc agtattatcc tcaaatgtta gcgcaggctt gtgaaagttt
    25501 cggtatcgat ttagatacac cattcgaaga attaccggaa gagcatcagg aaatcatctt
    25561 gaatgggaca gatgatcttt tccatttcca ttatgaaaat gattttggtg gcgttcgcga
    25621 tgtagaaacg actttcgaag gggtattgaa gaatatcgag cgtcgttatc atgatacgaa
    25681 cagtgatttc acgcgtgagc aaatgcgtct ttatatgaca gaattaactt gtcagacatg
    25741 taaaggttat cgattgaatc cccaagctct atctgttcaa atcaatggaa cgaatatcgg
    25801 gcaaacaaat gagttgtcta ttcaaaaagc agtagatttc ttctcaaact taacgttatc
    25861 tgaacaagag aaagtaattg ccaaaccgat tttaaaagaa gtaaatgaca gactttcatt
    25921 cttggaaaat gtgggactag actatctaac tttgagtcgc gcttccggaa cattatctgg
    25981 gggagaagcg cagcgaatca gattggctac acaaattgga tcgaatcttt ctggagtttt
    26041 gtatatttta gatgaaccat cgatcggatt gcatcaacgc gacaacgatc gactgattgg
    26101 ctcattaaag aaaatgcgtg atcttggcaa caccctcgtt gtagtcgaac atgatgaaga
    26161 tacgatgtgg gcagcagatt atttgattga cgtcggacct ggggccggag aacaaggcgg
    26221 acaaatcgtg gctgcaggca ctcctgaaga agtagctaat gatgaaaatt ctttgacagg
    26281 gaaatatctt tcagggaaaa aatcaatccc tgtaccaaaa gaacgccgta aaggtaatgg
    26341 gaaagcaatc aagatcactg gtgcttcaga aaacaatctg aaaaatatta gtgttgaatt
    26401 tccattagga gaatttgtag cagtcacagg tgtgtctggt tctggaaaga gtacattggt
    26461 caatagtatc ttaaagaaat cgttagcgca aaaattaaat aagaattctg ctaagccagg
    26521 taaattcaag acaatttccg gctacgaaag tatcgaaaag atcatcgata tcgatcaaag
    26581 cccaatcggc cggacgccga gaagtaatcc agcgacttat acaagtgtat ttgatgatat
    26641 ccgtgggtta tttgctcaaa cgaacgaggc aaaaatgcgg ggttataaga aagggcgttt
    26701 tagtttcaac gtaaaaggcg gtcgttgtga agcttgtcgc ggggatggaa ttattaagat
    26761 cgaaatgcac tttttgcctg atgtctatgt tccttgtgaa gtatgtcatg gtaaacgata
    26821 taattctgaa acattagaag tgcattacaa aggaaaaagc attgctgata ttttggaaat
    26881 gacagtagag gatgctgtag aattcttcaa gcacattcca aagattcatc gcaaactgca
    26941 aacgattgtt gatgttggct taggttatgt gacgatgggg caaccagcaa cgacattgtc
    27001 cggtggtgag gcacaacgga tgaaacttgc cagtgaattg cacaaaatct ctaatggaaa
    27061 gaatttctat atactagatg aaccaacgac aggacttcat agcgatgaca tcgcccgctt
    27121 gttgcatgta ttacaaagat tagtagatgc tggtaacaca gttttagtga ttgaacacaa
    27181 tctagatgta atcaaaacag cagattatat cattgattta ggaccagaag gtggagaagg
    27241 tggaggaacg atccttgcga ctggaacacc agaagaaatc attaacgtaa aagaaagtta
    27301 tacaggtcac tatttgaaaa aaataatggt ataaagagga tagatagctg agatagttaa
    27361 aaaaacataa aaaaatgaat ttttgcttgt tttattaata tcagtgttct agaatcatta
    27421 catggtagtt ctttctacac tgattggtat agataaaaac ttcctataag ttcaatccgt
    27481 tcaaaaaaga attgagcaat cggaggactt tcctttgatt gcttttttct ttatggtatg
    27541 atattccttg tgtagttgga aaagaaaaac aagagattat gagtaagtga gagataatga
    27601 tgaacagtat tgaaaatgaa gaatttatcc ctatattatt aggaagcgac atgaacgttt
    27661 atggtatggc acgttctttt aatgaagcat acggcaaaat ctgccaagca tatgcttcgg
    27721 atcagttagc ccctacccgc tacagtaaaa ttgtcaatgt agaagttatt ccaggatttg
    27781 ataaagaccc tgtatttatc gagacgatgc ttcgtttggc aaaagaaaga tattctgata
    27841 agagtaaaaa atatcttttg attgcttgtg gtgatggata tgcagaattg atctcccaac
    27901 ataaacaaga gctgtcagaa tattttatct gtccatatat tgattattct ttatttgaaa
    27961 ggctgatcaa taaagtaagc ttttatgaag tttgtgaaga atatgatctt ccgtatccta
    28021 aaacattgat cgtcagagaa gaaatgttag taaatggaca tttggaacag gaattgcctt
    28081 ttgaattccc agttgctttg aaacctgcaa acagtgtgga gtatctttct gtccaatttg
    28141 aaggaagaaa aaaagctttt attttagaga ctagagaaga gttcgattta attttaggcc
    28201 ggatatacga agccggttat aaaagtgaaa tgattgtaca agattttatc ccgggtgatg
    28261 atagtaatat gcgtgtgcta aatgcgtatg tagatgaaga tcatcaagtt cggatgatgt
    28321 gccttggtca tccactatta gaagatccta caccagcatc gattggtaat tacgttgtga
    28381 tcatgccaga ttataacgaa aaaatctatc aaaccattaa ggcatttttg gaaaaaatcg
    28441 aatatacagg ctttgccaat ttcgatatga agtatgatcc tagagatgga gaatataaat
    28501 tatttgaaat caatttgaga caaggtcgta gcagtttctt tgtgacattg aacggcttga
    28561 atctggctcg ttttgtcaca gaagatcgag tgttcaacaa accctttgtt gaaacgacct
    28621 atggaacgaa tcaatcagat aaagcaagat tatggatggg tgtgcccaaa aaaatctttt
    28681 tagaatatgc tcgggaaaat gaagacaaaa aactagctga gcaaatgatc aaagaaaatc
    28741 gttacggtac tactgtattt tatgaaaaag accgatcaat caagcgctgg ttgttgatga
    28801 aatatatgtt ccataactat attccaagat tcaaaaagta ttttcatgtg aaagaaggct
    28861 agttcatgga gaattttttc agtattttag gcggaatggg cacgatggcg acagaaagtt
    28921 ttgttcgctt gatcaaccac cgaacgaaag ctacaaaaga tcaagaatat ttgaattatg
    28981 tcttattcaa tcatgcaaca gttcctgatc gtacagctta tattttagat cgatcagaag
    29041 aaaatccaat gccgtttctg ctggatgata ttgagaaaca aaatttattg cgaccaaact
    29101 tcattgtgtt gacttgtaac accgcacact acttttttga agagttacaa gcggcaacgg
    29161 atattcctat cttgcatatg ccaagagaag cagcaaatga acttgtccgt cagcatacga
    29221 cagggagagt agcgattcta ggaacagaag gaagtatgaa agctggaatc tatgaacgcg
    29281 aagtcaaaaa tcttggtttc gaaacagtga ttcctgatac tgcgcttcaa gaaaaaatca
    29341 attacctgat ctatcatgag atcaaggaat cggattattt gaatcaagag ctctattacg
    29401 aaatcttaga ggaagcggta gagcgcctaa actgtgaaaa agtcatccta ggttgcacag
    29461 aattatcttt gatgcatgaa tttgctgaag ataatcatta cccagtgatc gatgctcaat
    29521 ctattttagc ggatcgaacg atcgaacgtg cattagctga aagaagcgag gcattggata
    29581 cagcatcgga aaagtaaaaa aattggattt ggggcaaata tcctaaaaga tatttggtcc
    29641 aaatcttttt gtaaaagaaa aagaaaactg gtaatgatac gcccgggatg atataatttt
    29701 attatgcaca atgtgagagg ggttcgtaaa tatgacagat aatttgcaat tagtcatcat
    29761 aacaggtatg agtggtgcag ggaaaacagt agctatccaa agttttgaag atatgggcta
    29821 tttttgtatc gataatatgc cgcctcgatt gattccagaa ttctgggaat tgatcaaaga
    29881 atcaggtaaa gtcacaaaaa tggctttagg agtggatttg cgttctcgtt ccttctttga
    29941 agaaatccaa aacatgctga tcgaaatcga aaatacgaac ttcatcgaca cttctatctt
    30001 atttttagat gcttcagacg aagaactagt ggctcgctac aaagaaacaa gacgagcaca
    30061 tccaatggcg atggacggtt tgatcactga agggatacgt aaagaacggg cgatactaga
    30121 cgacttgaaa gcccaagctt ccgtgatcat tgatacgaca acattgacac cacgacaatt
    30181 acgtgaaaaa atcaatgagt cattcaaatc aaagggagac caaggatttc ggatcgaatt
    30241 tgtatcattt ggttttaaat acgggttgcc gatcgattcg gatattgtga tggatgtgcg
    30301 ttttttgccc aaccctcatt atatcccgga actaagacca ttgaccggaa aagatcagcc
    30361 agtctatgat tatgtgatgt cctttgatga aacgcaatca ttctaccata aatttttgga
    30421 tcttctggaa actgtattgc ctggatacat taaagaagga aaaagcagct tgacagttgc
    30481 aatcggctgt acaggcggtc aacaccgttc tgtggcattg actgaacgtt tggcaaatgc
    30541 tttagggaaa aactataaag tcaatgtgac acatcgggac aaggataaaa ggaaagagac
    30601 ggtgaaccgg tcgtgaaaat gaaaacctac cggataagaa aaccaaagat cgtagtggtc
    30661 ggcggtggca ctggtctgcc agttatcctg aaaagtttac gaaatcaagg agcagatatc
    30721 acagcagtag tgactgttgc agatgatggt ggaagcagcg gtgcaatcag agaatcgatc
    30781 gctatggctc ctcctggtga cttgagaaat gtcttagtgg cgttatcgga tatgccacaa
    30841 ttctatgaag atattttcca ataccgtttc aaaaaggaag atcagttttt agccaatcat
    30901 acgatcggta atctgatcat tgccgcagtt tccgagatgc ggggaagcac ttatgaggcg
    30961 attcaattat tagcaaaaat gatgcatgta gatggacatg tttatccttc ttcagaaact
    31021 cctttgacct tgcatgctgt ttttaaagac ggaacgactg cagtaggaga atctaaaatc
    31081 gcgatcaacc gtaaaaccat tgaccgtgtg tatgtctgca acacaaatga taaaagtgaa
    31141 gccaaagcgg ctcgaaaagt cgtttcagca attatggacg ccgacatggt cgttttggga
    31201 cccggaagtt tattcaccag tatccttcca aatttagtga taccagaaat cggcgaagca
    31261 atgctcaaga caactgctga aaccgtctat atctgtaata tcatgaccca aaaaggggaa
    31321 acggaacatt tcacagatgc cgatcatata cgtgttttac acaagcattt gaatcagcct
    31381 tttatcgata cagtattggt caatacggaa aaagtgcctg aagattatat ggacccagag
    31441 atctatgatg agtatctagt acaagtcgca cacgacttca acggattgag aaatgaagga
    31501 tgtcgagtga tttccaccga ctttttagaa ttgaaagatg gtggtgtctt ccacgatgga
    31561 gacaaagtag tagaagaatt gttccgttta gttttcggtt caaaatatta agcaatttat
    31621 tgttggagaa aggaggagaa taggatgtca tttgctgcag atgtgaagaa agaactaact
    31681 ggtttggaag ttcatcgaga acatgcgaaa gcggaattag ctgctttgct gcgaatgaac
    31741 ggctctttag gtattgtgaa ccagcagttt attttgaacg tccaaacaga aaatgctgca
    31801 attgccagac gtatctattc tcttttgaaa gatcattatc aggtacgaag tgagctactc
    31861 gttcgtaaaa aaatgaaatt aaaaaagaac aatgtctata tcgtccggtt gaagcaaggc
    31921 acaaaagatg tgttgatgga tcttgatatc atggatggta tgatgttcaa tggacacgtt
    31981 tcggacgaga ttatgggaaa ttcgcaaaaa atgcgttctt acttacgtgg tgcttttatg
    32041 gcctcaggtt cagtcaataa tccggaaacg agtcgttatc atttggaaat attttctatt
    32101 tatgaacagc ataaccaaga catttgcgat atgttaaatt attacggtct acatgctcga
    32161 acgcttgaac ggcgcaatgg ctatatttcg tatttaaaag gagcagaaaa aattgctgat
    32221 ttcttaacat tgattggtgc aaccaactca atgctccgat ttgaagatgt tcgaatcgta
    32281 cgggatatga gaaattcggt caatcgtcta gtcaattgtg agacagcaaa tctgaacaag
    32341 acgattgatg cggcttctaa acaaatcgaa aacatcgaat tgatcgaagc aaaggtcggt
    32401 ctacatgccc ttcctgaaaa acttcaggaa atcgcagaac ttcggcttca acatccagag
    32461 gtcagcttga aagaattagg ggaaatgatt ccctcaggtg caatatcaaa atcgggaatt
    32521 aatcaccgaa ttcgcaaaat aaatgaattt gcggaaaaac tgcgtgaaga agcagtttaa
    32581 tccaaagaaa aaactgatac atgaagcagg agatgcgaat gtatcagttt tttttaaaag
    32641 ctatacttgc ttttcttccg tcaaactata attccaactt tactggagta acataatgtt
    32701 gaaaggcttc tattgttttt taatacaatc gtataaaaag cggggagaca actgaatgaa
    32761 gattttagtt ttatacataa acttttgctt aatatagaag tcctgatata gataggatca
    32821 agtatttatc tataactgga gattaattaa aaactggaag gaactgctcg atcaaccttg
    32881 agaactgttt ttcttacttc tggtcaagat tctcgtggtt ggtggataag gatggttgat
    32941 aagttcattg gattagctag tcgaaaacaa ccaggtgtaa ttaatgtaga agttttaaca
    33001 aggggatgga gtgatttatt cagtgataat cataagttca taaatagtaa ttgggatgta
    33061 tggttggtat acgttatacc tgaacttgaa ctatcaagat ttggtttaga atttgagaat
    33121 cgatgtttat aaagggaggg caaaaaatgt gcttttttac aacttttact atcattatga
    33181 ttgcagtact ttttattttt ctagatatag caaagcgaaa tacagcattt ttattatatc
    33241 gggttttact tcgagcaggt ctcataacat ttatatcgat cgttggattt tttctattca
    33301 cagttattgt atttatttgg agaactacag caccaccatt gccagagatt acatatggag
    33361 aatttccgtt tagtcttgaa tatgaaatag atgaggaaag aattttgatt gaagatacgg
    33421 tgattgcaga atttatagga agttttagag ggaatgtgac aactcaacct agacgaagtt
    33481 ggagtataaa acttttaaat aatagtggag agttgaaagc atttcattat gaattcttaa
    33541 taatagaaag tgaagatgta acaatcactt taagtagtgg ctctgctgga tattttatga
    33601 atgatggtgg aagcaagcca cagctcacag tccgtgatcg tattgcaggt tttatgcatt
    33661 tttctcacta tgacttagaa gaagctcgta aaatacttgc agaatatggg atcacattaa
    33721 tcaattggga atatgcgcca ccgataagaa attttttcaa tgattattat tagtcttata
    33781 aaaaacagaa tgtaaaattt atgtgcgcga gtatttagtt ttccattttt tgtttgatag
    33841 atatatagca ttgttgaagc atgggatagt ggtgccaatt ttatcaatga ggttggtcag
    33901 gcagttaaca taattggtga tgctataaat ccatttaatt ggaattggag gaattaggtg
    33961 tggaaacagt gagattatgg atattcatga aaaattttcg ttcggctttg agatatgtta
    34021 ttctggaatc aaaatcaggt tattatctga ttgacacaga tcactatact ttttggggag
    34081 gctacctttt tccgattttt aattggataa tcccccataa ggttatgaaa attaacttgc
    34141 ctgcagaaga aataaataga ttaatactca acaaagattt acaaaggaaa agagagaaag
    34201 aacattctaa tgttgcttgg ataggtccag catttgcagt agtgacttct tcaattgtcg
    34261 gtcctatgct agagagtatt tatagtgatt tttctattgg aatacgttat ttatttgtta
    34321 ctttaagtat agctgttctt ttgtgcataa agggttatgt tagcaagaag aataaagata
    34381 ttttaacact aatcggtgta aacaatttat ctagtactaa aattatactg tttcctgaat
    34441 ctataaaaga aggatcaagg ttgttgataa tttttataat gcttatactg ttttctgttt
    34501 tatttggggt gatgtttata ga
//
LOCUS       DAFEIE010000029        34183 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFEIE010000029
VERSION     DAFEIE010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.029"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(82..777)
                     /locus_tag="LP345_001487"
     CDS             complement(82..777)
                     /locus_tag="LP345_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBL1760272.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(867..1967)
                     /gene="ychF"
                     /locus_tag="LP345_001488"
     CDS             complement(867..1967)
                     /gene="ychF"
                     /locus_tag="LP345_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBL1760273.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(1976..2167)
                     /locus_tag="LP345_001489"
     CDS             complement(1976..2167)
                     /locus_tag="LP345_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBL1760274.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(2188..3078)
                     /locus_tag="LP345_001490"
     CDS             complement(2188..3078)
                     /locus_tag="LP345_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBL1760275.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(3065..3832)
                     /locus_tag="LP345_001491"
     CDS             complement(3065..3832)
                     /locus_tag="LP345_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1760276.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(3844..4557)
                     /gene="rsmG"
                     /locus_tag="LP345_001492"
     CDS             complement(3844..4557)
                     /gene="rsmG"
                     /locus_tag="LP345_001492"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBL1760277.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(4789..6690)
                     /gene="mnmG"
                     /locus_tag="LP345_001493"
     CDS             complement(4789..6690)
                     /gene="mnmG"
                     /locus_tag="LP345_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBL1760278.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(6707..8104)
                     /gene="mnmE"
                     /locus_tag="LP345_001494"
     CDS             complement(6707..8104)
                     /gene="mnmE"
                     /locus_tag="LP345_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBL1760279.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            8403..8786
                     /locus_tag="LP345_001495"
     CDS             8403..8786
                     /locus_tag="LP345_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760280.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(8954..9712)
                     /locus_tag="LP345_001496"
     CDS             complement(8954..9712)
                     /locus_tag="LP345_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBL1760281.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(9730..10548)
                     /locus_tag="LP345_001497"
     CDS             complement(9730..10548)
                     /locus_tag="LP345_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL1760282.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(10545..10901)
                     /gene="rnpA"
                     /locus_tag="LP345_001498"
     CDS             complement(10545..10901)
                     /gene="rnpA"
                     /locus_tag="LP345_001498"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBL1760283.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(11019..11153)
                     /gene="rpmH"
                     /locus_tag="LP345_001499"
     CDS             complement(11019..11153)
                     /gene="rpmH"
                     /locus_tag="LP345_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBL1760284.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            11676..13010
                     /gene="dnaA"
                     /locus_tag="LP345_001500"
     CDS             11676..13010
                     /gene="dnaA"
                     /locus_tag="LP345_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBL1760285.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            13208..14338
                     /gene="dnaN"
                     /locus_tag="LP345_001501"
     CDS             13208..14338
                     /gene="dnaN"
                     /locus_tag="LP345_001501"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBL1760286.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            14567..14809
                     /gene="yaaA"
                     /locus_tag="LP345_001502"
     CDS             14567..14809
                     /gene="yaaA"
                     /locus_tag="LP345_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBL1760287.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            14796..15920
                     /gene="recF"
                     /locus_tag="LP345_001503"
     CDS             14796..15920
                     /gene="recF"
                     /locus_tag="LP345_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBL1760288.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            15917..17863
                     /gene="gyrB"
                     /locus_tag="LP345_001504"
     CDS             15917..17863
                     /gene="gyrB"
                     /locus_tag="LP345_001504"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBL1760289.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            17883..20354
                     /gene="gyrA"
                     /locus_tag="LP345_001505"
     CDS             17883..20354
                     /gene="gyrA"
                     /locus_tag="LP345_001505"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBL1760290.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            20590..20889
                     /locus_tag="LP345_001506"
     CDS             20590..20889
                     /locus_tag="LP345_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBL1760291.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            20939..21451
                     /gene="ssb"
                     /locus_tag="LP345_001507"
     CDS             20939..21451
                     /gene="ssb"
                     /locus_tag="LP345_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1760292.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            21477..21713
                     /locus_tag="LP345_001508"
     CDS             21477..21713
                     /locus_tag="LP345_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBL1760293.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            21856..23829
                     /locus_tag="LP345_001509"
     CDS             21856..23829
                     /locus_tag="LP345_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBL1760294.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            23835..24287
                     /gene="rplI"
                     /locus_tag="LP345_001510"
     CDS             23835..24287
                     /gene="rplI"
                     /locus_tag="LP345_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBL1760295.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            24561..25928
                     /gene="dnaB"
                     /locus_tag="LP345_001511"
     CDS             24561..25928
                     /gene="dnaB"
                     /locus_tag="LP345_001511"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBL1760296.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            26708..28000
                     /locus_tag="LP345_001512"
     CDS             26708..28000
                     /locus_tag="LP345_001512"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBL1760297.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            28736..29599
                     /locus_tag="LP345_001513"
     CDS             28736..29599
                     /locus_tag="LP345_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1760298.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(29728..31350)
                     /locus_tag="LP345_001514"
     CDS             complement(29728..31350)
                     /locus_tag="LP345_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1760299.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            31599..32120
                     /locus_tag="LP345_001515"
     CDS             31599..32120
                     /locus_tag="LP345_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL1760300.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(32306..34036)
                     /gene="spxB"
                     /locus_tag="LP345_001516"
     CDS             complement(32306..34036)
                     /gene="spxB"
                     /locus_tag="LP345_001516"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBL1760301.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
BASE COUNT        10369 a         6652 c         6747 g        10415 t
ORIGIN      
        1 tattatttaa ctatggataa acaaaatgag gttctttact acccctagat atctagcaaa
       61 atagctgatc tttttgctag tttatcttct tgggacggat aaacttccaa taatcccgta
      121 ttttttcttc aagtagtaac ggattgctaa agcagttgcc ccgataatga taactactac
      181 tggatctaat actggattga taactggtgg caatagtgtt gtcgcagaaa acagtacgac
      241 ccaaagaagt gtcgttccac ctaggataag caatgtctta cccattcctg gtttcttgct
      301 tcgatctgct ccgggatatt catattgata gatgtatttg tacatcatat aaaagaccca
      361 gccaccgatt gcagaaccta gaacgagtgt agaaaagcca taagctggcg ttgttccacg
      421 tgaaaacaat ccggtaatcg caatcatgat acttaataga ccaagcaaca gcaacgtatt
      481 atctaaccac atcaataaag gggtggatga attttttact tctgctggct tattgatgat
      541 tgcttccgtt ctttcagaga ctgtcccaaa caattgacgg gctgttcttc cgcctttttg
      601 ttctgcaact aaagtaggca gaatgtcatg aagggctttt actttttctt cttcagacaa
      661 attcgctgct tctaaagatt ttttcaaatc aaaaatgtac tgttgatttc ttttggttaa
      721 ttttgtttct aaactattgt tttcttttac gattgctcgt aattgttctg gttccattat
      781 ctaatagtcc tccttagccg ttccttttct caacggtcgt cacaaaagac attctaccat
      841 attctacagc tagtttgata gcccttttac acattaaagc ggaataacat tacgtcgccg
      901 tcttgtacga cataatcttt tccttctaat cgaacacgtc cagcttcttt tgctgcatgc
      961 atgtttccgt aatgatccaa gtcttcaaaa gagacagttt ctgcacggat aaatccgcgt
     1021 tcgaaatctg aatggatgat tcctgctgct tgtggtgctt tgattccttt tttgaatgtc
     1081 caagcacgta cttcttgttc cccagcagta aagtaagtag ctaagcctaa caaatcataa
     1141 gcagcacgga tcaactgatc caaacctgat tcttcgattc ctaaagcttc taaaaattcc
     1201 gctttgtctt cttcatctaa ttctgcgatt tcttcttctg cacgagcact gaccacgatc
     1261 acttctgcat tttcttctgc agcaaagttg cgcacttctt gtacataatg attcgcgtct
     1321 gcatctgcta cgtcatcttc tgagacattg gctacataaa gaattggttt tgtcgtcaat
     1381 aaaaatagtg atttaacgat tttttgttct tcttcagtaa attcgatcgt tcgggcagat
     1441 tttccttctt ccagtacagg tttgatttta tccagtacag ctagttctgc cactgcatct
     1501 ttatctttgg ttttagcaac ttttgctaca cgagtatagc gtttgttgat agattctaag
     1561 tctgctaaca ctagttccaa gttgatcgta tcaatatctt ctagtggatc aacacgtcct
     1621 tctacgtgag taatattatc atcatcaaaa cagcgaacaa cgtgacaaat agcgtctact
     1681 tggcggatat ggcttaagaa ttgatttccc aaaccttctc ctttacttgc gccttttacg
     1741 attccagcaa tatctgtaaa ttcaaaagtc gtcggaacag tttttttcgg atgtacaagt
     1801 tctgttaagc gttgcaaacg ccagtcaggt acttctacca tccctacgtt ggggtcgatc
     1861 gtcgcaaagg gatagtttgc tgcttctgct cctgcttttg tgatcgcatt aaacaaagtt
     1921 gattttccta cgttgggcaa cccaacaatt ccagcagtca atgccataaa tttattcact
     1981 ctttctctgc atttttttca attacttttt ttaatttctt ttcaaaatct cgacgggtca
     2041 tcatgacgat atgtccgcaa ttcatacatc tgattttgat atctgcgccc attcgaatga
     2101 cttcccagcg attcgtctgg caagcgtgag gttttttcat ttcaacgata tcgtgcaagt
     2161 cgtacataaa aatagcctcc tttttgttta ttcttcatca aattgaatat tcaagatatc
     2221 aagaattcga gtcaaatctt tttgagaaag atattcaatc tcgatcttac ctttcccatt
     2281 tttttcttgg atagctacac ttgtaccaaa tttatccatc aaacgatctt cgctttctcg
     2341 gatataatat ggtttttcct ttgctagcct tgggattttt ttcttttctt ttccatcatt
     2401 ttgatttaac tcagaaacaa gctgttccag ttggcggaca gttaaatttt cagttactgc
     2461 acgattggct aatttcaaga tcaatgtttt attttttaaa cctaacagcg tacgggcttg
     2521 tcccatagat aaacgctgat cttgtaccat ttccttgaca agatccggta aagaaagcaa
     2581 gcgcaaataa ttggcgatat aaggtctgct ctttcctaaa cgactagcta cttctgcttg
     2641 tgttagtttc aggtttttca tcagcatctc atatgcttct gcttcttcta acggattcag
     2701 atcttctcgc tgcaagtttt ccagcactgc tacttgcatc atcgcttctt cgtcaaagtc
     2761 tctaacgata gcagggatcg tttctttttc agctagtttg gacgctcgaa aacgtcgctc
     2821 ccctgcaata atctcatatc cttttactgc ggaacggcgt acgatgatgg gttgaaagac
     2881 acctgattgt tcaatagaat tagctagttc ctgcaaagat acttcttcaa atgttttacg
     2941 gggctgatac ggatttggtc gcagctcatt caatggtagc tggacaacgg tatcatcttt
     3001 tacatccacc gtctctaagt tttctaaatc ttgaaacagt gcatcgattc ctcggcctaa
     3061 tcctttactt ttcttcacga cttaccactt cctttgccaa tgcttggtag acttcagctc
     3121 ctcgagaacg tggatcgtag tcgatgatcg gttttccatg actaggtgct tctgataaac
     3181 gaatatttct tggaatgatc gtttcgtaaa ctttttcgcg gaagtattta cgtacttctt
     3241 ctacgacttc atttcccaga tttgttcgtg catcatacat tgtcagtaag actccctcga
     3301 tctctaattc tggattaaag tgtttttgga ctaaacgaac cgtattcagt aattggctta
     3361 atccttccaa tgcgtaatac tcacactgaa caggtatcaa aatcgaatca cttgctgtaa
     3421 atgaattgat tgtcagatgg ccaagagaag gcgggcaatc gatcaaaata taatcatact
     3481 gactgcttac ttctgctaaa gatcctttta atcttgattc tcttgccatc attgacgtca
     3541 attcgatctc tgctcctgct aattggagag tcgcaggcac aatactcaaa ttttcgtgtt
     3601 cagtgatcaa agttgcctca tcaattggca attcattgac tagaacatca tagatgtctc
     3661 ttgtcacatc aggttttctg atcccgacac cactggtagc atttccttgt gcatccatat
     3721 ccactagcaa tacttttttg ccaaggctag caagacaagc acctagattc accgtcgtcg
     3781 ttgttttgcc gacgccacct ttttggttcg caacagatat tatttgtgcc atctcttctc
     3841 ctcctatttg attggctgct tattaggcag tccgggcttt cttgggtatt tctttggggt
     3901 tggtttcttt ttttgaataa cgatgatatg ccgttgatca gagacattcg gcaaggtaac
     3961 cgcctcttct ttgaggaatt taccacctaa taaagcaatc gcttgttttg cttctgtcaa
     4021 ttcctcttca ctttttgctg ctttcaatgc ataaaaatag ccttcttgtt tagccaaggg
     4081 caaacacaat tccgctaaca cattcaaacg agcaaccgca cgagcagtga caaggtcaaa
     4141 tgatgcacga aagtgaggat tttgcccaaa tgtttctgcc cggtcatgat ataaggaagc
     4201 atcgattcct aataatcggg ttaactcaga taagaaggtt attcgtttat tcagagaatc
     4261 aacgatcgtt atctgcagtt ctggaaaggc aatttttaaa ggtatgctag gaaaccctgc
     4321 ccccgaacca acatcgcata aagataaagg ttgcgtaaag tctacttcaa atgctaatgt
     4381 aagtgaatcg taaaaatgct tcagatatac gtctttttca tccgtaatag ctgtaaggtt
     4441 catcttttcg ttccattcga ctaatgtccg ataataaata gcgaattgat tcatttgatg
     4501 atcggtaagc tctatccctt tttctgccaa ggattggcga aattcttctg gtatcataaa
     4561 tattcctttc attgtgaaac agcaattgtt tcacagattc tctccctact ttaacgcaaa
     4621 atctctagac atgcaatcct tccatatgga ttcttaaaaa tttgaaaagt aagaaaagcc
     4681 gatagacttt ttctttctag tatgactcat aaaatataca cagaagagag aactagcttt
     4741 gagcaatttc tgcaaaaact agttctctct tctatttatt attacgtatt acgctggttc
     4801 actgactttc gcaatcttcc cttgttcgat atagaccatt aggatactta ggtctgcagg
     4861 gtttacgcca ctgattcggc tagcttgggc aattgtttct ggttggattt tctgcaattt
     4921 ttgttttgct tctgttgcta atccgttgat tgctgcgtag tcgatgtttt ctggaatctt
     4981 tttcgcttcc atgcgtttta atttttctac tttttccatg gcttttttga tgtagccttc
     5041 atatttgatt tggatttcta cttgttcgat ttcttttcgt gtcaattctt cattttctgg
     5101 aataaaccgt agaagttctg cataagtaat ctcaggacgt cttaaaaagt cgcttgctag
     5161 tacaccatct tttaatggtg ccgcattaat cgttgctaaa aagtcttgga cttcttctgt
     5221 tggtttgatt cgtacattca tcaaacgttt gatttcttgt tcaactgctt cttttttctt
     5281 caaataattc ttgtattgat cttcttttac taagcctaca cggtgaccca tttctgttaa
     5341 tcgcaaatct gcattatcat gacgtaaaag cagacggtat tcagcacgtg aagtcagcaa
     5401 acgataaggt tcgttcgttc cttttgttac caaatcatcg atcatgacac cgatgtaacc
     5461 gtcacttcgt ttgatcacta aaggttcttt tccctgaact ttcaaagctg cattgatacc
     5521 ggcaatcagc ccttgtccag ccgcttcttc ataaccgctt gtaccatttg tttgtccagc
     5581 tgtataaaga ttttcaacga ctttagtttc taatgtcgga cggagctggt gtggctctac
     5641 tacgtcatat tcgatagcat atcctgtacg catcatttct actttttcta atccagcaat
     5701 agaatgaagc atgttgactt gaacatcctc tggtaaagaa gtagataaac cttgaacata
     5761 gacttcttcc gtatttaagc cttctggttc caaaaataat tgatgacgtg gtttgtctgc
     5821 aaaacgcacg atcttatctt cgatggatgg acaatagcga gcgcctaccc cttcaacgat
     5881 ccctgtaaac attggggcac gatgtaagtt gtctcgaata atttggtgag tcgtctcacc
     5941 tgtataggtc agccagcaag attcctgatc tagtttatag gcactatctg gtgtgctgaa
     6001 gctaaaatga ttcggctctt tgtcaccagg ctgctcttct gtaacagaat agtcgatcgt
     6061 acttgatttt actcgaggcg gtgttcctgt tttgaaccgt tcgatagcaa agccaagttc
     6121 ttttagatga ttcgctagtc caatagaagg ttgagagtta ttcggacctg atgaatattt
     6181 caattcaccg ataatgattt ctccgcgaag tgctgttccg gctgtaataa caactgcttt
     6241 ggcccggtag ctcgctcctg tggacgtcac tactccatga caaacaccat cttcgacgat
     6301 cagttcttcg acgattcctt gtcttagcgt caaatttggt tctttttcga tcgtatgttt
     6361 catttctgtt gaataagcat gtttgtctgc ttgtgctcgc aatgctcgga cagctgggcc
     6421 ttttcctgtg ttcaacatac gcatttggat ataggtttta tcgatattct tacccatttc
     6481 tccgcctaac gcatcgattt ctcgaacgac aacgccttta gctggtccgc ctacagaagg
     6541 attacatggc atgaatgcta ccatgtccaa atttattgtc agtaataatg tttttgatcc
     6601 catacgtgca gcagcaagtg cagcttctga accggcgtgt cctgcgccaa caacgatcac
     6661 gtcatacgca tctgcttcat aatgttccaa tcgtttgttc ctccttttat tttcctaaac
     6721 aaaattgact gaataattga gtgattagct catcttgtac actgtcgccg acaacttctc
     6781 ctagatagtc ccagcaacgc gtcatatcta tttgaacgag atccacaggc attcctgaat
     6841 caatacctgc aatgacttct tcaagtgaga gggaagcttt ttctaacaac gcgatatggc
     6901 gggtattaga aacataagta gcgtctcttt ctcctgtttc tccgctgaag aataaatcag
     6961 aaatagctga ttccaaacga tctagtccgt cgtttttagc tacggaaatt gaaaaaactg
     7021 gttcattttc gatcaatttc ttcaattttt cttgttccag ctgtgctggc aaatctgttt
     7081 tatttagaag aatgatccgt ttcaatccac ttgtcgcttc caataattgt tcatcttctg
     7141 ctgtcagtgg ttcgctttgg tttagaacaa gtaagatcaa gtctgcttct gctaatgctt
     7201 ttcggcttct ttcgaccccg atccgttcca ccacatcttc tgtttcccga attccagctg
     7261 tatcgattag cttgagcggt accccccgaa cattgacata ctcttcgatt acatctcgag
     7321 tcgttcctgc aatatccgta acgattgctt tttcttctct taacaaatgg tttaacaaac
     7381 ttgatttgcc gacatttggc cggccgatga ttgccgtact taacccttcc cgcagaacct
     7441 tcccttgctt ggatgtagca agtagcgctt ggattctttg ttggatcatc tgcgcttttt
     7501 caagcaataa cttcgtagtc aattcttcga catcatcata ttctggataa tcaatattta
     7561 cttctacttg tgctaatgtc tctaaaatct cttgtctcaa tgagcggatc aaagcagaca
     7621 gattgccgtc taactgatta agagctagtc ccattgcttt gtctgttttt gcccgaatca
     7681 aatccatcac agcttctgcc tgtgaaaggt caacacgacc attcaagaat gctcgttttg
     7741 tgaattcgcc tggctcagct aatcttgcac cttctcttaa caatagctgc aaaatttgat
     7801 tgactacaac gatcccaccg tgacaattga tttctactac atcttcccgc gtaaatgtct
     7861 ttggtgctct catcacggag accatgactt catcgacaag ctgattgctc ttgggatcaa
     7921 cgatatgtcc ataatggatc gtatgacttg gtacttctga taatcgtttg tttccagatt
     7981 gataaacttt atctgctagt tgcacagctt gatcgccact taaacgaacg atactgattg
     8041 caccttctcc aggtggggta gaaattgccg caatcgtatc aaattctaaa gtaatttcag
     8101 ccattttttc acttcctttt tcattttgcg cacaaaaaaa gtgcccactc caccctttat
     8161 gcacaataaa cggtgaactt cgcactttga ctgcttgttc ttgattaaat tctggtcata
     8221 gattatcaca cttgctataa ggaatcaagt gtttaaaaca attagatgaa gttgagcctg
     8281 ttctgcttcc attaccttat atttaattgt ccttggatgt ctctttgcgt tctttggttt
     8341 attcgaagag aagatactgt ataaacaagg ctttatcttt cttaaaaaaa acggtacact
     8401 aaatggtagc gctatctaaa ctatacactt ttgaaaggag aaaatatgtg agcccgttca
     8461 gatctgctgc attggaagaa gaaagtgacc ctcggatcaa cgatgtcgtt ttatctacag
     8521 ggaatatcaa ccagaaatat atcgtccgcg atatcgtttt tgttgtggaa tgcttagaag
     8581 ctgatttgtt tgacccatct tttcccaaag atgacctttt cttaacaacg aagaggaaat
     8641 taaagacgaa ggtacttgaa tatggtgcga atgcagtaat caactgtcat tttgagtatc
     8701 agcaaaaaaa acgcgacgga aagtattttc tggaactttt tgcttatgga acagtgatcc
     8761 aatttatcca aacaacgatt ggttaaatga aacagacaaa aaaagcggat caaaactgaa
     8821 gacagtttcg atccgctttt ttctatcaaa gttagtgact acttcatcgt atactctgat
     8881 aagaatgatt tctagtaaaa tatacttggt ttgaaaaact ttgtcaacgt gatttattca
     8941 aaaagtaatg gaatcaataa tattttttag caggttctac tactaaataa cgataaggtt
     9001 cctcaccttc cgaatgtgtt tttacatgtt catctttgct taatgcagca tggatttgtt
     9061 tacgttcaaa tgcaggcatt ggttctaaga aaacaggctg ccctgtccgt tttacttttt
     9121 cagccgtgcg atcagctaaa cgctgaatga tctcttggcg cttttcacgg taattgccta
     9181 cattgactac tacagacagc ttatttcttg ctaaacgatg gatgaagact tgtgccagat
     9241 attgcaatgc attcagtgtt tttccatgtt tcccaatcag tatgccttgc ttttgtgttt
     9301 ctaaatggaa aacaaccata ttatttgatt ctctttccat tttgacaaga gctggagcat
     9361 caagctgttt tgaaatttca gtaagataaa ctgccaattc cgttaaagct gcttcatcac
     9421 ctagctcact tacttcttct gttttttctt caagaatcgt ttcgttgact acctcgatct
     9481 cagctgttgg ttcttcttcc aaaatttctt ctacagtctg ttctactgtt tcagaaactt
     9541 tttcgctgat acttggctgg atcgaaagcc gtgcattctt tcgacccatt cctaggaaac
     9601 ctttttttcc ttcttccagt atttcgattt cgacttggtc tttggccaaa cccaaatcag
     9661 ccagacctag ttggacagct tcgtctattg ttgcagcttc ataaatcggc attagcatta
     9721 cctcccctat tatttccgtt ttttcttagg attcattgct ttcttaagag cacgttctct
     9781 ttcgcggatt ctccgtgctt cttcttcacg ctcttttcga attttgaaag ggttgttgat
     9841 cagcagcgtt tgtacaactt ggaaggcatt ggaaactacc cagtataatg aaagaccgct
     9901 ggctaaattg acacccatca ctaaaatcat tacaggcatc acgaaattca tgatcttcat
     9961 tgatgcattc gattcaattt gactcatgct agataaatac gtacttgcaa aagtaaagat
    10021 tgctgctaaa atcggcaaaa taaatgttgg atccgcgttc cctaagttca accataagaa
    10081 atgcccttgt ttcaactctg gtacacgtga aatagattgc cataacgcca tcaagattgg
    10141 catttgtact aataaaggaa gacaaccagc atatggattg acgccatttt ctgcatataa
    10201 acgctgctgc tcttctctta acttactttg tgtttccgga tctcttgaac tatattgttg
    10261 ctgcagtgct tttaatttcg gttgtaattc ttgcgtttta cgcatgctct ttgtttggaa
    10321 atgcatcaac ggcaatagga tcacgcggat gatcagtgta aataaaatga tccctatccc
    10381 tgcattacca aatgacaacg ccttgatcgc ctcagcaaag taataaacaa tataacgatc
    10441 ccaaattcct gtactctgtg cgctgacttc cccagttccg caaccggata agacgatgac
    10501 caaactaacg ataccggcca tcaaaagtaa acgtttgtat ttcttcactt actcttttcc
    10561 tctctgtcga ttatttttgc aagttttaag acgtggacta aattggagcg aacctcatca
    10621 taagtcaacc ccttcacact tggtctagca atcacaataa aatccaactc cggatcaatt
    10681 tcttctttta tagaataaac tgctgctcgg atttttcgtt tgacttcatt gcggtttacc
    10741 gcgttgccga ccttttttcc tacagataaa ccaactcgaa aatgaggctg tcccggtttt
    10801 tccaaacggt aaacgacgaa tttgcggtta gcaaaagaat ctcccgtatg gaacacggct
    10861 tgaaactctc gttctttttt tactcgatac gcttttctca ttagttttct ttccttttct
    10921 atctctcact tacgctcata atcataccat aattacgatt gtcctttcat catttcccta
    10981 aaaaagagta taaaaaaaac cactgaaacc ccagtggcct aagctgaaag aacttttctt
    11041 cctttgcgac gacggctagc taacacacga cgtccatttt tagtactcat acgtttacgg
    11101 aatccgtgaa ctttttgacg tttacgttta tttggttggt atgttctttt catatattcc
    11161 acctccaaaa tgttcttatc tattttataa acacagacat actttgatag tataacgaca
    11221 aagtagtgat tttgtcaata taaaatagaa gatcgattgt taaaacttat ccacaagatt
    11281 atttttttct atgggaatcc tatgtggaaa aagttatgca cagggattat ccacagataa
    11341 taaaaggctg gttttacaca gaaaacacac gtgtaaaaaa agtaatccac aatcaggcga
    11401 tttcctgtgt attccgtctc ctaactattg gtatatctgt attttttatc cacagacgca
    11461 agaggaaatc tattggtttt tacgagtttt ccacctgtgc attagtggtg tggaaaactt
    11521 tttttgacaa ctgtgttttt ctcttttttc tttttgtcga ttgtgtggat aattgtaatt
    11581 aaaaaatttt tttcttcggt ttctgtggaa aactattgaa aaaaatgcta aattagtact
    11641 agttattcac tttttaatga aggaggaggc cttatatggt atccctcgat gctttatgga
    11701 atgaattaaa agcaacatac caaaaggatt tatcgcctgc tagctataat acatggatcg
    11761 aaacagcgaa ccctcgaacc cttgatcaaa accagctcgt tgttgaggtt cctagcaaga
    11821 ttcataaaga atattgggaa aaaaacctgg cgacaaaaat cgttgaagtc ggttatatgt
    11881 tatcaggaaa tgagattatc cctcgcttta ttactggcga agaagcagag caagaagaag
    11941 ttatagaaga aaaaaatcca aaagttgtgg cacctagtcc gctaaaaaaa gccatgctga
    12001 accctaaata tacctttgat acgtttgtca ttggtaaagg aaaccagatg gctcatgcag
    12061 cagcgctcgt tgtagcagaa gatccaggtt ctatttataa cccgctcttc ttttatggag
    12121 gcgtgggact tggtaagact cacttgatgc atgcaattgg tcatcaaatg ctgcaaagtc
    12181 agcctaatgc caaagtaaaa tatgtaagca gtgaaacttt tgctaatgat ttcatcaatt
    12241 cgatccaaaa caaaacagca gaagagttcc gtcaagaata tcgaaatgtt gatttactgc
    12301 tagtggatga cattcaattt tttgcagaaa aagaagctac gcaagaagag tttttccata
    12361 ctttcaatgc cttgtacaat gaagggaaac aaatcgtact aaccagtgat cggttgccaa
    12421 acgagattcc gaaactgcaa gaacgccttg tttctcgctt tgcatggggg ctgtctgttg
    12481 atattacacc gccggatctt gaaacaagaa cagcgatttt acgtaaaaaa gcggcggctg
    12541 aacgtctaga gatcccagat gacacactaa gctacatcgc aggacaaatt gattctaaca
    12601 ttcgtgaatt agaaggtgcg cttgttcgag tgcaagcttt tgctgcgatg aatagtgaag
    12661 atatttcgac tagtctagct gcagacgcac tgaaaacgtt aaaatcagga aaaggacatc
    12721 ctcaattgtc aatcctgcag atccaagaag aagtggcaaa gtattatcac atccaattga
    12781 aagatctcaa aggaaagaaa cgcgtcaaat ctattgttgt tcctagacaa atcgctatgt
    12841 atttggcacg tgagctcaca gataattctt taccgaaaat cggagctgaa ttcggtggca
    12901 aggatcatac aacggttatc catgctcatg aaaaaatcca gcagctgatg gattctagtg
    12961 tcagtatgca aaatgaagta tcagaaatca aaaacttttt actaaattaa tttgtcgatt
    13021 ctatcaactg aaaatagcat gtggataaaa gaaaaaaacg ttcaaaagtt atacacactt
    13081 tttccacagc tgttttttcg tttctctctt acgttttttg agttttccac agaatcaaca
    13141 tgccctatta cttttattat tctttttaac taataataaa taaacaaaca ttcaaaggag
    13201 atacatcatg aaagttactt taaaccgagc tagctttatg caggaattgc aaactgttca
    13261 acgagctatt tcaagcaaaa ccacgatccc tattttgaca ggtgtaaaaa tcacactgac
    13321 acaagaaggt ttgactttga cggggagcaa cgctgatata tcaattgaaa cttttttgtc
    13381 tgttgaaaac gaaaaagcaa atatgcaaat cgaatctact ggttccattg ttttacaagc
    13441 acgtttcttt agcgaaatca ttcggagact tcctgaagaa acatttactt tagaagtttt
    13501 agaaaataaa caagtagcga tcacttctgg aaaagcgaat tttatcgtaa atggattaga
    13561 tgcagataac tatcctcatc ttcctgttgt cgaaagccat aaccagatga aattacctgt
    13621 acacgtattg actaaactaa tcaacgaaac agtttttgct gtctcacaac atgagagtcg
    13681 tccaatcttg acaggtgtgc atttcatttt atctgataat tctttattag ctgtagctac
    13741 tgattctcac cgtctaagtc aacgcgtgat tccagtagaa caagcggctg atcattttga
    13801 tattgttatt cctggaaaaa gtttgatcga attatctcgc tcattaacaa atgaagaaga
    13861 aatcgtcgaa atcagcatta tggaaaacca agtgttgttc aaaacagaaa cgatgtattt
    13921 ctattcccgt ttgctagaag gaaactatcc agataccaat cgtttgattc cttcaagttt
    13981 taatacagag gttgaatttt ctgttcctag ctttttagcg gcgatcgaac gggcttcttt
    14041 actttctcat gaaggccgta acaacatcgt tcgtttatct attcgtccag atgcggttgt
    14101 tttatacgga aattcgccag aaatcgggaa agtagaagaa agcttgagtt atacagcaag
    14161 cagtggcgat ccattagata tttctttcaa tccggattat atgaaagcag cgttgcgtgc
    14221 atttggagat atgagcatca aagtgaaatt tatctctgct attcgtccat ttacattgga
    14281 accaacggaa gatggcgttc aatttattca gctgattact cctgtacgta caaattaaca
    14341 atgattttca atgttcttga aaatttaatt gaaaagaaat agaaaaaata aaattttaaa
    14401 cagaaggccc taaaatctct tttaaggctt tctgtttatt tttgtttaaa tcaccttttt
    14461 tagattaaat cgtcttatat ggaaaaatat atggataaat ttgttttatt gcgaaaaaaa
    14521 aggtataata gagtatactt ttaataatga aaatgaggga tgggcattga aacaacaagt
    14581 cattctaaat acggaattca tgacgttggg ccaaatgttg aaagaagtca cagttatcgg
    14641 tagtggcgga caagcaaaat ggtatttggc agaaaacact gtgttagtcg atggcgaacc
    14701 agaaaatcgt cgtggacgca aactttatcc cggcatgatg gttgaagttc cagaagtagg
    14761 aacttttttt atggtaaaaa aaggaaacga cgataatgag gctgaataag ctgtatttaa
    14821 aaaattatcg aaattacgaa gagctgaaca tcgaattttc caagaacctc gtcatctttt
    14881 taggagaaaa tgcgcaagga aaaacgaatc ttttggaaag tatctacgta ttagctatga
    14941 cgcgaagtca tcggacaagt agtgagcagg aattgattgg ctggactgac gatcaggcga
    15001 tgattcaagg agagatcaca aaaggttcat ccactcttcc attagaaatc ttattatcta
    15061 aaaaaggccg aaaaaccaag atcaaccata tcgaacagaa aaagttaagt acttacgtgg
    15121 gacaaatgaa tgtcatttta tttgcaccag aagatctttc tttagtaaaa ggcagcccgc
    15181 agaccaggcg gaagttttta gatatggaat taggccagat caatccaatc tatctttatg
    15241 atcttgtcca ataccaagca attttgaaac aaagaaacca gtacttgaag caattgaatg
    15301 aaaaaaaaca aactgatttg ctttatttgg atattttgtc cgaacaacta gcagcgtttg
    15361 gcagcaaagt attgaaagca agagcacagt tcgtcaagcg attggagttt tgggctaatt
    15421 ctttgcatca gcaaatcacc catcaaaaag agcagctgga aatcgagtat ctcaccgcag
    15481 tcgattcttt agaaacacat acgcaagagc aaatccaaga acaatttctc gcacttttga
    15541 accaaaataa aaagaaagac ctttttcggg gaacaacgac agttggtcct catcgtgacg
    15601 atctttcctt ttttattaat cagaaaaatg tgcagactta tggatcgcaa ggacagcaaa
    15661 gaacaactgc actaagtgtc aaattagcag aaatcgattt gattaaagaa gagacagggg
    15721 aatatccaat ccttttgtta gatgatgtga tgagcgagct ggatgataat cgtcaactcc
    15781 atctgctaga aacaatcgaa ggaaaagttc aaacgttctt aacaacaacg acacttgacc
    15841 atgtaaaaaa taaaatgact gttgaacctg agatttttta tgttcaacaa gggaaactaa
    15901 aaggagaaga aactgaatga cagaagaaag aagtttagta gaacgcgcta aagagtatga
    15961 tgccagtcag attcaagtac ttgaaggact tgaagccgtt cgtaaacgac ctggcatgta
    16021 tatcggttcg actagttctg agggtctgca tcaccttgtt tgggaaattg tcgataattc
    16081 gatcgatgaa gtattagcag gttttgcaac gaaaatccat gtgattattg aaaaagacaa
    16141 cagtatcacc gttattgacg acggtcgggg gatacctgta gatatccagg caaaaactgg
    16201 acgtcctgca gttgaaacgg tctttactgt tttacatgct ggaggaaaat tcggcggtgg
    16261 tgggtacaaa gtttctggtg gacttcacgg agtaggatct tctgttgtta acgcgctttc
    16321 tacacagctt gatgtcaaag tatacaaaga aggaaatgtg tactatcaag aatatcgtcg
    16381 tggagctgta gtggacgact taaagattat cgaacaaacg gatcgccatg gaacaacggt
    16441 tcactttacg ccagaccctg aaatttttac agagacaact gagtttgatt tttcaaaatt
    16501 ggctacccgg atccgtgaac ttgctttctt gaaccgcggg atgcgtatat cgattgaaga
    16561 caaacgagaa gaagaaccag tcatcaatga ataccattat gacggcggga ttaaaagtta
    16621 tgtcgaatac ttgaatgcaa acaaaaccgt gatttttcca gaacctgtat atttggaagg
    16681 tgaacagcaa gatatcgcag ttgaagtctc tatgcaatat acagacggct accattccaa
    16741 tatcatgagt tttgccaaca atatccatac gtatgaaggc ggaacacatg aatcaggatt
    16801 caagactgct ttaactcgtg tgataaatga ttatgcccga aaacaaaagc tgatgaaaga
    16861 aaatgacgac aacttgaccg gtgaagacgt gcgagaagga ttgacagctg ttatttctat
    16921 caagcatcct gaccctcaat tcgaaggaca aacaaaaaca aaattgggca attccgaagt
    16981 acggacagtc actgatcggt tatttagcga acatttcatg aaattcttgc tggaaaaccc
    17041 aagtgtgggc cgtcaaattg ttgaaaaagg attactagct tccagagctc gtctagcagc
    17101 gaaacgtgcg cgtgaagtaa cgagacgtaa aggtgcttta gagattagta atctgccagg
    17161 aaaattagcg gactgctcta gcaacgatcc tgaaaaatgc gaattgttca tcgtcgaagg
    17221 agattcggcc ggcggatcag ctaagcaagg tcgtaatcga gagtttcaag ccatcttgcc
    17281 tattcgtggg aaaatcttga atgttgaaaa agcaagcatg gacaagatct tggcaaatga
    17341 agagatccgg tctttattta ctgctatggg tacagggttt ggagaagatt ttgatgtatc
    17401 gaaagctcgc taccacaaat tagttatcat gactgatgcc gatgtcgacg gcgcgcatat
    17461 ccgtacattg ctgctgactc ttttttatcg ttacatgcgt cctattgttg aagctggata
    17521 cgtctatatt gctcagccac ctttatacgg ggtaaaacaa gggaagaata ttacgtatgt
    17581 acaaccagga aaaaatgcag aagaagagtt gaaacaagtc gttgcttcac ttcctgcctc
    17641 accaaaacca agcgttcagc gttataaagg acttggagaa atggatgatc atcaactatg
    17701 ggaaacaact atggacccaa gcaatcggat gatggcccgc gtcagtgtgg acgatgctat
    17761 tgcagcagat cagatatttg aaatgttgat gggggatcga gtagaacccc gtcgtgcatt
    17821 catcgaggaa aatgcacact atgtgaagaa cttagatatt taatcatgaa ggaggaaaaa
    17881 gaatgagtga agaaatcaga gaaaacatcc atgatgtcaa tctaaccagc gaaatgaaag
    17941 actccttcat cgattatgcg atgagtgtta ttgtcgcacg tgcacttcct gatgtcagag
    18001 atggtctgaa acccgttcat cgccgtattt tatacggcat gaacgaatta ggtgtaacac
    18061 cggataaagc ccataaaaaa tctgccagaa tcgtcggaga tgtcatgggt aaataccatc
    18121 ctcatggaga ctatgcgatc tatgagtcaa tggtacggat ggcacagcca ttcagctacc
    18181 gttatatgct agtggatggt catggaaact ttggttctgt tgacggtgac ggtgccgccg
    18241 ctatgcgtta taccgaagca cggatgagca aaatcgctac agaaatgctg cgtgatatca
    18301 ataagaacac tgttgatttc caaagcaact atgatgatac agaaaaagaa ccagttgtac
    18361 tacctgctcg cttcccgaat cttttagtga acggaacaac ggggatcgcc gtaggtatgg
    18421 ccacgaatat cccacctcat aacttgtctg aggtagtagc ggctatcgat ttgctgatgg
    18481 ataatcctga tgtgacgacc aatgaattga tggaagtatt acctggacca gattttccaa
    18541 caggtggttt ggttatggga aaatcaggaa tccgaagagc gtatgaaaca ggtaagggtt
    18601 ctattaccgt acgtgcaaaa gttgagatta ctgagatgcc aaatggtaaa gaacggatca
    18661 tcgtgacaga attgccttat atggtcaata aagcaaaatt gatcgaacgg atttctgaac
    18721 tgcacagaga caagcgtatc gaagggatca cagatttgcg ggacgaatct tcccgtgaag
    18781 gtatgcggat cgtcattgac atccgtcgtg acgccagcgc atctgttatc ttgaataact
    18841 tatataaatt gacatccttg caaaattcat ttggattcaa tatgttggcg atcgaaaaag
    18901 gtgtgccgaa agttttgagc ttgaaacaaa ttcttgaaaa ctatatcgaa catcagcgcg
    18961 aagtcatcac aagacggaca gtctttgaaa aagaaaaagc agaagcaagg gcacacattt
    19021 tagaaggttt gcgtattgct ttggatcata tcgatgaaat cattgcgatt atccgcgggt
    19081 ctaaatcaga tgacgaagca aaagcgacga tgatcgaacg gttcgattta tccgatcgcc
    19141 agtctcaagc tattttagat atgcgtttac gccgattgac cggtttggaa cgggaaaaaa
    19201 tcgaaaatga ataccaagaa ctcttaaaac tgattgaaga tttaactgac attctggcaa
    19261 gaccagaacg tgttacagaa atcatcaaga atgaattagc agacttgaat caacgatttg
    19321 gtgataaacg acgcacagaa ttactagtcg gtgaggtctt aagtctggaa gatgaagatt
    19381 taatcgaaga agaagaaatc gttattacat tgacaaacaa tggttacatc aaacgtttgg
    19441 caaataatga attcagagct caacgaaggg gtggacgtgg tgtccaagga atgggtatcc
    19501 acaatgacga cttcgtcaaa aatctggttt cttgttctac ccatgataca ttgttattct
    19561 ttacgaataa cggaaaagtg tatcgggcaa aaggatacga aattccagaa tacgggcgca
    19621 cagccaaagg aataccaatt atcaatttac taggtatcga ttcgagtgaa agcatccagg
    19681 caatcattgc ggtgacggga gaagcagaag aaggccacta tctcttcttt acgacgcgtc
    19741 aaggtacagt aaaacgtact tctgtcactg cttttgctaa catccgaagt aatggtctga
    19801 tcgcaattgg tttgaaagaa gacgatgagc tcgtcaatgt gctactgaca gatggtcaat
    19861 ctaatatcat tattggaaca cataacggct actctgtcac tttcaaagaa gaagcagtcc
    19921 gcgatatggg acgtacagct tccggggtta gaggaatacg cctgcgtgag gaagattatg
    19981 tcgttggggc agccttaatg aaggaagatc aagaagtatt agtgatcaca gaaaaaggtt
    20041 acggaaaacg gacaaaagta tcggaatatc cagtgaaagg ccgcggaggt aaagggatca
    20101 aaacggcgaa catcactgaa aaaaatggtc cactagctgg attgaccact gtttctggag
    20161 atgaagacat catgctgatt acagataaag gtgtcattat ccgtttcaac gtatcgactg
    20221 tttctcaaac tggacgttca acattaggcg tacgtttgat gaagatggaa gctgatacga
    20281 aagttgtcac gatggcagca gtcgaaccag aagctgcaga acaaacagtt gaagaacaag
    20341 gatcagaaga atagccatca agactaattg tgtaagctag caagaatgac cgattaaaaa
    20401 atctggttat tcctgctggc ttttttgatt agttgaattt ctcttaaaat attcgaaact
    20461 gttcattctg tattgctttt gaccaaaata gagtgtataa tcagagcttg tgagtagtct
    20521 aattaattag ataactctcc ttgctcttag gaacctaaga gccgaaagtc cacagggagg
    20581 tgaatatcaa tggaaaacac gaaatatgaa atcatgtaca ttattcgtcc aaacattgat
    20641 gaagaagcaa aaactgcttt aatcgaacgt ttcgatgcaa tcttgaaaga taacggagca
    20701 gaagttatcg aatcaaaaga ttgggaaaaa cgccgtttcg cttatgaaat gaacggttac
    20761 cgtgaaggta tctatcacat cgttaaagta tcttctccat catcagcaaa tgctgtcaat
    20821 gaatttgacc gtcttgctaa aatcaacgac gatatcattc gtcacatgat tgttaaagaa
    20881 gaagcttaat tgttgtttca tgtgaaacaa tagaaaacga tgagaggaga tgactatttt
    20941 gattaataat gttgtattag ttggacgtct gacgaaagat ccagatttgc gttacacagc
    21001 aagtggtacg gcagtcgcaa catttacttt ggctgtgaat cgtaatttta caaaccaaag
    21061 cggcaatcgc gaggctgatt ttatcaactg tgtgatttgg cgcaaatcag cagaaacttt
    21121 agcaaactat gctcgtaaag gaacactttt aggtgttact ggacgtatcc aaactcgttc
    21181 ttatgataat cagcaaggac aacgtgtata cgtgacagaa gtagtagctg acaacttcca
    21241 attgctggaa agtcgttctg catctgaaaa tcgccaacaa agcggcggat tccaaagttc
    21301 tggtcaatca gctggcggat ttggcggaaa caataactct aatcaaacat ctcaatcatc
    21361 caacggtatg cctgatttcg accgtgatac ttctgaccca ttcggctcaa gttcaacgat
    21421 cgacatttca gacgatgatt taccattcta aacgaatttg ataggaggga aatagaatgg
    21481 cacaacaaag aagaggcgga cgtaaacgtc gtaaagtaga ctacattgct gctaaccata
    21541 ttgaatatat cgattataaa gatatcgaat tactaaaaag atttatttca gaacgcggta
    21601 aaatcttgcc acgtcgtgta actggtacag gcgctaaaaa ccaacgtaaa attactgttg
    21661 caatcaaacg cgctcgtatc atgggcttgc tacctttcgt tagcgaagac taataaatcc
    21721 taggaattga atgactgatc cttttgatca gctattcaat tccttttttt ctgtaaaaat
    21781 aacctctatt cgtttagtcg ctcgaatgac gaaagttatg gtaaaatcaa attagtcata
    21841 tatgggagga aaattatgga aaataaaaac aatcatttat ccccgaaacc tctcttcctt
    21901 atcctgttta tattaatcga agtattggta gtcttaattt taccatttcg ttttgttagc
    21961 gcttcggtca ttctattgat gaatttatgg ggtgttcgct attggttgaa aatgaaacgt
    22021 tggcttattt taaataaacg tgaaaaaatc cagcaggctt cgactgtagc tgaaaccaat
    22081 ctagcttatg tctcagaagt catgcctgta ggagtgattg cttatcagcc atcaagccaa
    22141 aaaatcgaat ggctcaatcc attagcattg aaaatcaaag atcaaagtgg attaacagag
    22201 gaagaattgc tagatacttt ttttactgca aaagaaaaaa agaaaaacca agtctatcta
    22261 gcagataaaa catttcagtt tgatatggat acagtaaagg gtgttgttta ttttaatgat
    22321 attacccaaa accagttgtt aaaactccat cagacgaaca gtcagccggt gattggtatt
    22381 ttatctattg ataactatgc agatgccatt gataaattgg atgacaaaga gatttcttat
    22441 ttgaactctt tcgtcactac actagtttct gactggatga atgaatacca tgtctttttc
    22501 aaaagaatca acgcagaacg gtttttcttc gtagcacaga tgatcgatct gaaaaagatg
    22561 atggataaaa aatttgattt gctggatcgc tttcgagcag aagctgaaaa acagagctcg
    22621 cctatcaccc ttagtatggg gattgcttat ggctcaagaa ccctcgatga aatcggtgga
    22681 gaagctcaga ataatttaga tgttgcttta gtccgtggag gcgaccaagt tgtcgtgaaa
    22741 gaggtaaaag aaggagcaaa acctgtttat tatgggggga aatctgctaa gaatgtcaaa
    22801 cgcacgcgtg ttcgttctcg agcgatgagt accgctttgc gtcggatttt tgatgaaaca
    22861 ggcgatgtgt ttatcatggg gcacaagttt ccggatatgg atgctttagg ctctgctttt
    22921 ggtgtcagtt gtctggcacg cttcaaccag aaaaaagctt acatcgttat caacgagaac
    22981 gagatcattc cagatgtaga acggtgtctt gaagaaatcc ataagcatcc tgaattagaa
    23041 atgcaactaa tctctccaga acgtgccata gagctgaaaa aagaagagga cctcctcgtg
    23101 atggtggatt accataaacc ttctctatcg atctctcagg gcctatatga gcaatttgat
    23161 aagattgtga tcattgatca ccatcgtcgt ggggaagagt ttccaagtaa acctctgctg
    23221 acttatatcg aatcttcagc ttcttcagct tcagagctag tttctgagct gatccaatac
    23281 caaagcagca aaacaaatcg cttagatcgt tttgaggcca cattattgct tgcagggatg
    23341 gttgtagata caaatagttt caatgtccgt acaactgcac gaacttttga cgttgccagc
    23401 tatttaaggt cttgtggagc agacgcatcc ttagtacaat atttattgag ctcggattta
    23461 gcgacatact tggagatcag caatttgatt gctggaagcg actatgtgac ttctgatatt
    23521 gttgtggcgg cagggacaga cgaaaaagag tataatagtg ttatagcagc aaaaacagca
    23581 gatacattgc tttcgatgat caatatcaat gcagctttcg tcattacaaa gcggacagac
    23641 ggcttgattg ggatcagtgc cagaagtacc ggcacgatca acgtccaaat catcatggaa
    23701 tccttaggtg gcggaggaca cttcacaaac gcagctactc aactggaaaa tacgacagtt
    23761 gaggaaacaa aacagaagct atttgctgca atcaaagaaa atatgaatca aatatatgat
    23821 aaggagtaat ccaaatgaaa gtaatttttt tacaagatgt aaaaggaaaa ggtaaaaaag
    23881 gggacatcaa agaagttcca gcaggttatg cacaaaatta tctaatcaaa aataacttgg
    23941 caaaagaagc aacgaaaagc agtatcagtc agttagcagg acaaaagaaa gcacaagaaa
    24001 aacacgaagc tgaaatcttg gaagaagcta aaaagttaaa agaattcttg gaaaaagaag
    24061 atactgtagt cgaattgaag gcgaaagcag gggaagacag ccgtttgttt ggttcgatcc
    24121 cttcaaaaca aattgctgaa gggttaaaca aacaatacaa aatcaaatta gataaacgaa
    24181 aaatcgaatt agaaaatccg atccgttcac taggctacac aaacgtacct gttaagcttc
    24241 atcatgaggt gacggctacg atcaaagttc atgtcgtaca agaataacaa atcttgatag
    24301 cgatgttcag ctggtaagta taaccagaag gaaaaaagac aaaccgaaat ttatctgaga
    24361 aaacagctgc agcaatgaaa gcaaaagctg caaatcgatt tcagattgat ttcggtttct
    24421 tttttgggaa cagcaaaata gcataaagaa aacgagtata ataaaagaga actatttttt
    24481 tattacactt tcggtacgaa tgatgacttt tctctcattt tcttgtaaaa tgaagcaatt
    24541 gaagacaagg agcgatacgt atgaatgaag tgtggcagga tcgaatccca ccgcaaaata
    24601 ttgaagctga acaagcggtt ttaggctctg tttttcttga cgcagaaacg atcattgatg
    24661 ccatggagta catagagcca aaagactttt atcgtcgtgg ccatcaaatt atttttgaga
    24721 caatgatcga gttaaatgat cgtaatgaag cgattgacgt ggttactgtc aaagaccggc
    24781 tggaacaagc caatttgtta gaagatgccg gtggtttaag ttatctctca gacttggcat
    24841 tagcagttcc gacagcagca aatatcgtct actatgcgaa aatcgttgaa gaaaaatcat
    24901 tgctgcgtac attgatccag acagcaacag gaatcgttac gaaaggattc gagcaaggag
    24961 aagaagttca aacaatttta gatgatgccg aacgcagtat cttggaggtt tcggaaaaaa
    25021 gaaatcgaag cggcttttta tctattgctg aagtactgaa ctccacgatt gaaaatatcg
    25081 atcgactagc tcaaaacaat gaagaaatca caggtctacc aactggctat caaggtctgg
    25141 ataaaatgac agcaggtttc cagcccgaag aactaatcat tcttgctgca cgtccagcgg
    25201 taggtaaaac agcgtttgca ttgaatattg ctcaaaatgt aggaacaaaa acagatcgtt
    25261 ctgttgcgat atttagtttg gaaatggggg cagaatctct tgtaaatcgg atgctttgtg
    25321 cagaaggttc gattgaggcc agccatttac gtacaggtca gctttcggaa gaagaatggt
    25381 cgaatctgat cgttgcgatg gggagtcttt ctcgagcaaa tatttttatc gatgatacac
    25441 cagggatcaa aatctctgaa atccgtgcga aatgtcggaa actagcgcaa gaaaaaggca
    25501 atctaggctt gatattgatc gattatttgc agttgattga aggtaacggt aaagagaacc
    25561 gtcaacaaga agtatcagat atctctcgcc aactgaaaaa actggcgaaa gagctgaaag
    25621 tacctgtcat tgctctttca cagttatctc gtggagtaga acagcgacaa gacaaacgac
    25681 cagtgctaag tgatattcgt gaatccggat caattgaaca agatgcggac atcgtagcct
    25741 tcttgtatcg agatgattat tatgaaagag aaggcggaga tgacgatgat ggaaacgagc
    25801 caaaaaatga caacgtcatc gaagtcatca tcgagaagaa ccgaagcggt gcacgaggaa
    25861 cagttgaact actgtttatc aaagaataca ataagttttc gtcgctttcg ccaagagaag
    25921 aattttaaag aagaggttgt gagccttgag caatcccgag agctctcgta agaagatgca
    25981 aggagtaacc gcaggaacga ctagagtact taatttaaac agatctccaa agggattgtg
    26041 acaaaagtct tgtcacagtc cctttttccg aataaacggt gttcaatcag ctgacccttg
    26101 gtattagctc agcaaacgtc aaaatatgag gaactatttt gacgtttgtt tctctaatac
    26161 tcaggtcaaa acgctgatct tacgacctct tttccttaaa cggtgttctc ctgccaactc
    26221 ctcggtcaca agtcacaata tcatcaaaca tgagaagcag ttttttgaaa ttgctccttg
    26281 tgactcagag ttaaacggca ggctcacaac ctctttctta aacggtgttc aaaagcttgc
    26341 atctgcggta atacgcccaa tcaaacgaaa aatatgagaa gctatttttg tttggctgtt
    26401 cttattactt gatgcaggac agctttttca caacctctga ttcacggtgt tccaaaagta
    26461 gcttcttcga aaaataagtc gaaatttcac aaaaatttga gaagcaattt tcgtacattc
    26521 cttcttattt cttgaagctg accacttctg ttacaacctc ttttttaata accattctaa
    26581 aaagataaag ttcgtttttt aagcgttttt ataaaataaa aataaaaatc attcgatttt
    26641 atttgaaata tgtatctatt attgatacaa tggttcagga ttaaataata tagaacgagg
    26701 tgttcacatg tcatctgtag tagtagtagg tacgcaatgg ggcgatgaag ggaaaggaaa
    26761 aatcacagac tttctcagtg aaaatgctga agtgattgca cggtaccaag gtggcgacaa
    26821 tgcagggcac acaattaagt ttaacggtgt gacttataaa ctgcatttga ttccttctgg
    26881 gattttttat aaagacaaga tcagtgtgat cggaaacggc gttgtagtca atcctaaatc
    26941 attggttaaa gaattagctt atttacatga aaaaggtgta gaaacaagta atttgcgtat
    27001 ttctgaccgc gcgcacgtaa tcttgcctta tcatatcaaa ttggaccaat tacaagaaga
    27061 tgctaagggc gaaaataaga ttggtacaac gattaaagga atcggacctg cctatatgga
    27121 taaagcagct cgtgtaggta tccgtattgc agacttatta gataaagaaa tttttgaaga
    27181 acgtcttcgt ttgaatctag atgacaaaaa ccgtcaattt gtaaaaatgt ttgattcaga
    27241 accacttgat tttgacgata tttttgaaga atattatgaa tacggacaac aaatcaaaca
    27301 atacgtcaca gatacttccg ttatcttgaa tgatgctttg gatgcaggca aacgcgtgtt
    27361 gtttgaaggc gcacaaggtg taatgctgga tatcgaccag ggaacttatc cttttgttac
    27421 ttcttctaac ccagtagccg gtggggtaac aatcggaagc ggtgtagggc cttcaaaaat
    27481 caataaagtt gtcggcgtct gcaaagccta tacgtcacgt gtcggtgatg gaccatttcc
    27541 aactgaatta tttgatgaaa caggagaaca aatccgcgaa gtaggacgag aatacggtac
    27601 gacaactggt cgtccgcgtc gtgtaggctg gtttgattct gtagttatgc gccattctaa
    27661 acgagtttca ggtattacca acctatcttt aaactcgatc gatgtattaa gtggattgga
    27721 aacagtaaaa atttgtacgg cttatgaatt agatggcgaa ctaatctacc actatccagc
    27781 aagcttgaaa gagttgaacc gctgcaaacc aatctatgaa gaattgccag gctggtcaga
    27841 agacattaca ggatgcaaaa cacttgcaga actgccagaa aacgcacgta actatgtacg
    27901 tcgtatctca gagcttgttg gtgtacgtat ctcaacattt tctgtcggac ctgatagaac
    27961 acaaacaaac atcttagaaa gcgtctgggc gcaaatctaa ggataaaaac gacgactgaa
    28021 tcaggacgtt cttaccagag cgagtcgaag tgtttatcta tacgataata ataacttgaa
    28081 cactgtttat tcagaataag ggactgtgac aaaaaccgtg tcacagtccc tttttccgaa
    28141 caaacggtgt tcaaaagctt gcatctacgg cactaagccc aatcagatga aaaatatgga
    28201 gtgctatttt tatctgattg ttcttactgc ttgatgcaga gcagcttttt cacaacctct
    28261 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
    28321 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
    28381 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
    28441 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
    28501 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
    28561 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
    28621 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
    28681 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
    28741 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
    28801 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
    28861 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
    28921 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
    28981 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
    29041 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
    29101 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
    29161 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
    29221 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
    29281 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
    29341 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
    29401 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
    29461 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
    29521 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
    29581 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
    29641 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
    29701 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
    29761 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
    29821 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
    29881 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
    29941 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
    30001 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
    30061 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
    30121 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
    30181 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
    30241 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
    30301 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
    30361 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
    30421 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
    30481 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
    30541 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
    30601 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
    30661 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
    30721 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
    30781 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
    30841 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
    30901 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
    30961 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
    31021 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
    31081 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
    31141 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
    31201 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
    31261 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
    31321 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
    31381 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
    31441 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
    31501 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
    31561 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
    31621 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
    31681 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
    31741 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
    31801 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
    31861 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
    31921 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
    31981 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
    32041 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
    32101 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
    32161 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
    32221 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
    32281 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
    32341 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
    32401 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
    32461 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
    32521 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
    32581 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
    32641 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
    32701 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
    32761 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
    32821 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
    32881 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
    32941 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
    33001 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
    33061 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
    33121 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
    33181 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
    33241 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
    33301 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
    33361 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
    33421 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
    33481 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
    33541 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
    33601 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
    33661 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
    33721 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
    33781 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
    33841 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
    33901 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
    33961 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
    34021 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
    34081 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
    34141 gtcatgtttt tgggaatatg ctagagtagt acatagatag att
//
LOCUS       DAFEIE010000030        28126 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFEIE010000030
VERSION     DAFEIE010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.030"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            6..305
                     /locus_tag="LP345_001517"
     CDS             6..305
                     /locus_tag="LP345_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1760302.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="LP345_001518"
     CDS             378..1739
                     /locus_tag="LP345_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL1760303.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="LP345_001519"
     CDS             1761..2021
                     /locus_tag="LP345_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760304.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="LP345_001520"
     CDS             2035..2787
                     /locus_tag="LP345_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBL1760305.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="LP345_001521"
     CDS             complement(2881..3486)
                     /locus_tag="LP345_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1760306.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="LP345_001522"
     CDS             complement(3539..4513)
                     /locus_tag="LP345_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBL1760307.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="LP345_001523"
     CDS             complement(4891..5610)
                     /locus_tag="LP345_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1760308.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP345_001524"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP345_001524"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL1760309.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="LP345_001525"
     CDS             7161..8558
                     /locus_tag="LP345_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1760310.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="LP345_001526"
     CDS             8639..9079
                     /locus_tag="LP345_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1760311.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="LP345_001527"
     CDS             9227..9553
                     /locus_tag="LP345_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1760312.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="LP345_001528"
     CDS             9554..10303
                     /locus_tag="LP345_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760313.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="LP345_001529"
     CDS             complement(10383..10838)
                     /locus_tag="LP345_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL1760314.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="LP345_001530"
     CDS             complement(11265..11540)
                     /locus_tag="LP345_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760315.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="LP345_001531"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="LP345_001531"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBL1760316.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP345_001532"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP345_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL1760317.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="LP345_001533"
     CDS             14770..17436
                     /locus_tag="LP345_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1760318.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="LP345_001534"
     CDS             17800..18552
                     /locus_tag="LP345_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1760319.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="LP345_001535"
     CDS             complement(18574..19728)
                     /locus_tag="LP345_001535"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBL1760320.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..21148
                     /locus_tag="LP345_001536"
     CDS             19913..21148
                     /locus_tag="LP345_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBL1760321.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKSFISLRHLNGAVN"
     gene            21148..22353
                     /locus_tag="LP345_001537"
     CDS             21148..22353
                     /locus_tag="LP345_001537"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBL1760322.1"
                     /translation="MEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIPMGIAQN
                     FQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKSEYQAVI
                     NAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDVKDAMGA
                     NMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNKEIGEQI
                     AKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAARNGLYQ
                     GLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQVIAAVG
                     LAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKMNQQTAI
                     QILEKIREK"
     gene            complement(22683..23387)
                     /locus_tag="LP345_001538"
     CDS             complement(22683..23387)
                     /locus_tag="LP345_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760323.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23574..23819)
                     /locus_tag="LP345_001539"
     CDS             complement(23574..23819)
                     /locus_tag="LP345_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760324.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23836..24687)
                     /locus_tag="LP345_001540"
     CDS             complement(23836..24687)
                     /locus_tag="LP345_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1760325.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24853..25857
                     /locus_tag="LP345_001541"
     CDS             24853..25857
                     /locus_tag="LP345_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBL1760326.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26098..26454)
                     /locus_tag="LP345_001542"
     CDS             complement(26098..26454)
                     /locus_tag="LP345_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1760327.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26822..28009
                     /gene="tuf"
                     /locus_tag="LP345_001543"
     CDS             26822..28009
                     /gene="tuf"
                     /locus_tag="LP345_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL1760328.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
BASE COUNT         8974 a         4941 c         5804 g         8407 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaagtt ttatcagctt
    21121 acgccatctg aacggcgcag tcaattaata gaaaaaaatg tattgacaca agaaactgcg
    21181 ttgatttttc aggaacaaac actttctgaa gagctctccg atcacatgat cgaaaaccaa
    21241 gtgagtgaag tggaaatccc aatggggatc gcgcagaatt ttcaaatcaa tggcaagaaa
    21301 aaatggattc cgatggcaac agaggaacca tctgtcattg cagctgcaag taatggtgca
    21361 aaaatctgtg gaaatatctg cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt
    21421 ctatcaggaa aatcggagta tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag
    21481 ctgattcttt gtgcaaatga aagttatcct tcaatcgtga aacgcggggg cggtgttcaa
    21541 gatatctcta ctcgggaatt catggggagt ttccatgcat acttatctat tgatttttta
    21601 gtggatgtaa aagatgcaat gggcgctaac atgatcaact cgattcttga gagtgtggca
    21661 aacaagttac gggagtggtt ccctgaagaa gagattctat tcagtatttt aagtaatttt
    21721 gctacagaat cattggcttc tgcctgttgt gaaatcccat tcgaacgctt agggagaaac
    21781 aaagaaatcg gtgaacaaat tgccaaaaaa atccaacagg caggggaata tgcgaagctt
    21841 gacccttacc gtgcagcaac gcacaacaaa gggatcatga atggtataga agctgtagtg
    21901 gcagctacag gaaatgatac acgtgcggtt agcgcttcga tccacgccta cgcggcaaga
    21961 aatggattat accaaggatt aacagactgg cagatcaaag gggataaact agttggaaaa
    22021 ctaacggtgc ctttggctgt tgccacagta ggcggagctt ccaatatcct gccaaaagca
    22081 aaagcatctt tagctatgtt agatattgat tcagccaagg aactagcaca agtaattgct
    22141 gcagtagggt tagctcaaaa cctggctgct ttgcgtgcat tagttacaga aggaatccaa
    22201 aaaggccaca tgggacttca agctcgttca ttagcgatct caattggggc tattggtgag
    22261 gaaatcgagc aagttgcgaa aaaattacgt gaagcagaaa agatgaacca gcagacagct
    22321 atacaaatat tggaaaaaat ccgggaaaaa taaaaaagca atatctttag aagaataaag
    22381 caagatttac agttatttta tttactgcag atcttgcttt tttctctatc agaaaatatg
    22441 tttattatta gaatttttta tagttaaggt taggcatctt aagaaatcag gcaactccaa
    22501 gatatcttca ggtagaagag aagtcgccta acattgtagg atcataggtg atttgttgga
    22561 caggtcaagc tgatatttga gcctgatgtt agaaggaatt tctttttact tgctgtagaa
    22621 attattatat gactaaaaag gctgggattt taaatcccag ccttttatga caaatagaat
    22681 ttttatcgat cagtaatcgc tgtcgctgca aattgttcga tcaaaggaat caaagtcaat
    22741 ttgactttgt atttccgttc gagtgctttt tcgataacga actcattttc agtagtcata
    22801 gaaatagttg ctaatttacg aggttcatca gcattttttt cattaataac tacttcatgt
    22861 tcattttgtt ctgtgtaaaa tttaggatac tcagcaacgg cttttgaaaa atcagcaaaa
    22921 cttaaagcgg cattcgtatc agttgagcgt gtattttcag ttgtgtccgc ttttggtttt
    22981 tccgtttttt cttctggcac actgactgtt tcttctgtaa ctggtgtcgc aacagcttgc
    23041 gcagttggtt catcgttttt caatcgttga tcattccagt aagacacgat ttcaataaga
    23101 agattgtcac ggaatcgttc gaaaatcccg ttttctcctg aacgaattct ctttaataca
    23161 gtattgaagt tgtcatcgat tggcacgttg atccgtgtat cttcatttgt tttcccagct
    23221 aatccgatcg ttaagatttg acggtttttg ggatcaagca tgacttgtaa cggcaaacca
    23281 taacgtcgca agctctcttc ttctagagaa cggaataatt gtcctcttac accatccaat
    23341 gaaggacgga attgatttaa taatttttgt ttctgttttt tcttcatatg ttctctcctt
    23401 cgctcatacc ctttcgatta taagaaaaaa acagccaaat gaaaaggagt aatgcaaaaa
    23461 aacttgcgta tacgcaaatt acaacagaaa aatttgcgta ttttcccgtt ttttgaaaga
    23521 aaaataaaaa atggaacgga ttatgtatat atacataatc cgttccattc tttctatttt
    23581 ttcggtatca aggcaaaaac aggtagttca ggtgaataaa tgacttcatg ttcgtgccag
    23641 ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat ttgatcatgt
    23701 gtccagtttc ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa gacaaaatcg
    23761 gaatgaaaag tctgggtaac ttcttccgag agagaattca agcgttcgat tggatccata
    23821 aaatcacctt tcgacttaaa attgggtagt atctgggtct tttgctttgc cgactacacc
    23881 atctaactga tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa ataattcagt
    23941 attttctttg attctgcttg gtgtcactga cttaggaaga ggaaggaatt cgtgttgcag
    24001 cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga tttgtttcat
    24061 ttcaggcaca tcgaagattt taccagtgcc taatggacta tatgcttcga ggatcatatc
    24121 atgttttttt gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa ggaaaacttg
    24181 attgaccatc ggcataattt ttgctgtttt tgctagtgta tctagatggt ggggtaagaa
    24241 attgctcaca ccgattgctt tgattttacc tgcttcatac agttcttcaa atgctcgcca
    24301 tgtatctgca tttgcttgtt cccaattatc acgaaaagca acagggtttg gccagtggat
    24361 caaaaacaga tctaaataat ctgtttggag cttcttcaat gattcttcaa aagaagacat
    24421 cacaagttca tagctgtggt ttgcattcca taattttgtt gtcaagaata tctcttctct
    24481 aggaattcca ctttccttaa tcgcttggcc gacgctttct tcattcttgt atccttgggc
    24541 agtatcgata tggcgataac ctgcagccag cgcttcttta acagaggaaa cagcgacatc
    24601 cccatcaggt gtttgccatg tgccgaatcc tactaccggg atttcgtaac catttgatag
    24661 acgataagtg cttgttaatg aattcatact ttcagctcct tttttattcg ttcaactata
    24721 agtgtagcgc atttttcgaa aaaaagaatc cattttgttt ctactcttga aatttttgtt
    24781 taaaagaaaa tgattttgat tctggtattt ttgatttttt ttccgtaaac taagacagaa
    24841 gggaatgaga aaatggatat ctatttaaaa aaagcaattc tgcatattat tgacagagaa
    24901 actggttctc cagtcttttc acaaaaagag ctggatctga caaaagaata tattcgtgat
    24961 tttcttcaaa agaagatcca aaaaatctct tctgctcaaa caaaaactgg acaactagca
    25021 gaagaaagca tgatcgttga atcacttaaa atcgctcaag aaaattttgt ggaagcaagt
    25081 gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc acctagtgca
    25141 gatgtatttg ttgtcttgta tgaattagat acagtgatgt acttatcttt attgaaagtc
    25201 aattatcgtg aggcttacac tcactttgtt gaagcagacg aagcagggat cgacaaccgc
    25261 ttgattttga atcgagcaat tctaggggcg aaaacacaaa aagcagatga agcattcgct
    25321 gtgaatttga ctgattggac ctacgaatta attgaaaaaa aatatgagtt ttctggcaaa
    25381 aaagagcttt atttttctgg aagagtgatc gaaagtgttc ctgcaccttc tttagaagaa
    25441 aatgtaaaag tgatccaaaa agtagccaag catcttggaa aaaaatttga gacagaagaa
    25501 tttgatatca tggctgattt gaaagaagct gtctatgata cgatagaaga aaaaggtcgg
    25561 ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc aaaaatggct
    25621 tttaaagaag aagtacaaga gcaaggattt gtcccagaag cacctcctgt aaaagaagta
    25681 caagaaattt ctgagaaaaa atttggaaaa caaaaattca agctatcaaa cgggatcgaa
    25741 ctgatcgtac cagtagatgt atatcgcaac ccagatttga ttgaatttgt gaataatccg
    25801 gatggtacga tatccgtgat gatcaaaaat gtggatgaag tattgaatcg tttataaaaa
    25861 tgactagaat attaggtgtt caagtaccag tgatcagtta aatgaattgt gtcaagagaa
    25921 ggatcggaaa agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa gaacactttt
    25981 gtctcacgct ctaaacacgt ataaacggcg gaagcagaag caactccttc ttatttcttg
    26041 gagttaaacg cttctgtccc agcctctttt tatctaataa aattttaaga ccatttacta
    26101 attatcgatt ttttctgccg catttttagg cacttcagaa gcctttattt cttcccagct
    26161 taatacacct ttacgaggat tgactttgag tttaagatac gcattcatct ttaatggatg
    26221 ttctctttct tcgcgaagcg tcacctgttt tttttcacca tctttattat aagccgcttg
    26281 cttgtaggta taagtcgtga atttctctcc gttatctgct tgggtagctg acatttcgcc
    26341 attcgtcgtg atttttgtat aataagcttc gccgccgtaa aaataatgat aagctgcaaa
    26401 acttccgccg agaaatatgc ctaaaacgac aagtacgcca attaattttt tcatgtactt
    26461 cacctctttc cttattatta acgaaataga agatttcgtc tattgaaagt tgttggcaac
    26521 agctgaattt taaacttttc ctcattttgt tcttattgct tcaaaagaaa gttaaggact
    26581 atcttgaagt ttttctcaaa aaacacattt ttttatttat aaaaggtact tttttcgcgt
    26641 ataagacaga cgagtgctct tagttgactt tgaccaatat tgacgtataa taagcttagt
    26701 tcgaatctta caaaaagtaa gtcggacgta ttctttttga tttagtcaaa aaaagactat
    26761 aataaaaagg tgagagctga aatttttcag tgatctatat tatttaggag gtttgtaaat
    26821 tatggcaaaa gaacattatg acagaagtaa accacacgtt aacattggta cgattggaca
    26881 cgttgaccat gggaaaacta ctttaactgc tgcgatcact acagtattag gcaaaaaagg
    26941 cctagcaaat cctcaagact atgctagtat tgatgcagct ccagaagaac gtgaacgtgg
    27001 gattacgatc aataccgcac acgtagaata tgaaacagaa aaacgccact acgcgcatat
    27061 tgatgcacca ggacacgcgg actatgtgaa aaacatgatt acaggggcag cacaaatgga
    27121 tggtgcaatc ttagttgttt ctgcaactga cggtccgatg cctcaaacac gtgaacacat
    27181 tttattgtca cgccaagttg gtgtaaaata cctgattgtt ttcttgaaca aagttgattt
    27241 agtcgatgat gaagaattga tcgatttggt agaaatggaa gttcgcgagt tattgagcga
    27301 atatggtttc ccaggcgatg acactcctgt gatcaaaggt tccgcattaa aagcattgca
    27361 aggcgatcca gatgctgaag ctgctattat ggaattgatg gatacagtag atgaatatat
    27421 cccaacacca gaacgtgata cagataaacc attactattg ccagtggaag acgtcttctc
    27481 aattacaggt cgaggaactg ttgcctcagg tcgtattgat cgtggtgctg ttcgtgtcgg
    27541 tgatgaggta gagatcgtag ggatcaaacc tgaaacacaa aaagcagttg taacaggtgt
    27601 agaaatgttc cgtaaaacgt tagattacgg ggaagctggg gataacgtag gcgtgttgtt
    27661 acgggggatc caacgtgacg atatcgaacg tggacaagta cttgctaaac caggttccat
    27721 tactccacat acaaaattca aagcagaagt gtacgtgttg acaaaagaag aaggtggacg
    27781 tcatactcca ttcttcaaca actatcgtcc acagttctac ttccgcacaa ctgatgttac
    27841 aggaacaatc acattgccag aagatacaga aatggtcatg cctggtgaca acgtgacgat
    27901 tgatgttgac ttgatccatc caatcgctgt tgaaaacgga acgacattct caattcgtga
    27961 aggcggacgg acagtaggtt caggtatcgt tacagagatc gaagcataag aaacgcgact
    28021 cgaatatttt ggtaatgaaa aatgtttaaa ataaaagagc ggtccaaaca ggatttctgt
    28081 ttggaccgct ctttgttctt caattgtata agaagagatt gtagaa
//
LOCUS       DAFEIE010000031        27633 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFEIE010000031
VERSION     DAFEIE010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.031"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            119..766
                     /locus_tag="LP345_001544"
     CDS             119..766
                     /locus_tag="LP345_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL1760329.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            850..1794
                     /locus_tag="LP345_001545"
     CDS             850..1794
                     /locus_tag="LP345_001545"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBL1760330.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1929..3380
                     /locus_tag="LP345_001546"
     CDS             1929..3380
                     /locus_tag="LP345_001546"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBL1760331.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3401..4237
                     /locus_tag="LP345_001547"
     CDS             3401..4237
                     /locus_tag="LP345_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL1760332.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4237..4896
                     /locus_tag="LP345_001548"
     CDS             4237..4896
                     /locus_tag="LP345_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1760333.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            5022..5711
                     /locus_tag="LP345_001549"
     CDS             5022..5711
                     /locus_tag="LP345_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760334.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5717..6673
                     /locus_tag="LP345_001550"
     CDS             5717..6673
                     /locus_tag="LP345_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBL1760335.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6717..7229
                     /locus_tag="LP345_001551"
     CDS             6717..7229
                     /locus_tag="LP345_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1760336.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7485..8033)
                     /locus_tag="LP345_001552"
     CDS             complement(7485..8033)
                     /locus_tag="LP345_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1760337.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8122..9303)
                     /locus_tag="LP345_001553"
     CDS             complement(8122..9303)
                     /locus_tag="LP345_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBL1760338.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9539..11047)
                     /locus_tag="LP345_001554"
     CDS             complement(9539..11047)
                     /locus_tag="LP345_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBL1760339.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            11206..11397
                     /locus_tag="LP345_001555"
     CDS             11206..11397
                     /locus_tag="LP345_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760340.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11600..12517
                     /locus_tag="LP345_001556"
     CDS             11600..12517
                     /locus_tag="LP345_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBL1760341.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12510..13583
                     /locus_tag="LP345_001557"
     CDS             12510..13583
                     /locus_tag="LP345_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760342.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13731..14249
                     /locus_tag="LP345_001558"
     CDS             13731..14249
                     /locus_tag="LP345_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760343.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            14230..14622
                     /locus_tag="LP345_001559"
     CDS             14230..14622
                     /locus_tag="LP345_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBL1760344.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14698..15633
                     /locus_tag="LP345_001560"
     CDS             14698..15633
                     /locus_tag="LP345_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBL1760345.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15766..16545
                     /locus_tag="LP345_001561"
     CDS             15766..16545
                     /locus_tag="LP345_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL1760346.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16538..16855
                     /locus_tag="LP345_001562"
     CDS             16538..16855
                     /locus_tag="LP345_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL1760347.1"
                     /translation="MTKLYLLLLVVCLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            17099..18709
                     /locus_tag="LP345_001563"
     CDS             17099..18709
                     /locus_tag="LP345_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1760348.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18866..19714
                     /locus_tag="LP345_001564"
     CDS             18866..19714
                     /locus_tag="LP345_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1760349.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            19945..20424
                     /locus_tag="LP345_001565"
     CDS             19945..20424
                     /locus_tag="LP345_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760350.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            20457..22685
                     /locus_tag="LP345_001566"
     CDS             20457..22685
                     /locus_tag="LP345_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1760351.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            22814..24457
                     /locus_tag="LP345_001567"
     CDS             22814..24457
                     /locus_tag="LP345_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL1760352.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKINK"
     gene            complement(24530..25075)
                     /locus_tag="LP345_001568"
     CDS             complement(24530..25075)
                     /locus_tag="LP345_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBL1760353.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(25098..25583)
                     /locus_tag="LP345_001569"
     CDS             complement(25098..25583)
                     /locus_tag="LP345_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1760354.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(25573..26385)
                     /locus_tag="LP345_001570"
     CDS             complement(25573..26385)
                     /locus_tag="LP345_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBL1760355.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(26524..>27633)
                     /locus_tag="LP345_001571"
     CDS             complement(26524..>27633)
                     /locus_tag="LP345_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL1760356.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         9048 a         5026 c         5526 g         8033 t
ORIGIN      
        1 tttttcttta tattttcata ataaaagttt ggttctttaa tttttaaaca tgacagaaaa
       61 ttttttcttc gttatacttg taatagaata ctattttata acaaagggga tcgaatcaat
      121 gaaaaaaact gttatttata ctagtttatt tgcagctttg tttttagctg cttgtcaatc
      181 aaataccaat caaggcacat ctgggaatac gtcttccagt agcgaacagc gctcttcaca
      241 ggtatcggac tcctcaacaa aagcaagcac atcttcgtct agccagacaa aaagttctag
      301 tgaagcaagt actcagtcag atatcaaagt gtctgcagct cgtgcgatcg aattgttcca
      361 agataaatac ccagatactg caattactag tttggaatta gatagtgatt ggggatctta
      421 cttctacaag atagaaggtg tcgatgatca aaaagaatac gaagcaagaa ttgatgctca
      481 aaatgaaaaa atggagacag agaatccaga aactctagat cgagatgaac aaaatggtca
      541 aaagaaaaaa gaagatggtc tggatgttga taaattgatc acgattgagg aagcagcaaa
      601 aatcgccgtc gacaaagtag gaagcggtac ggcaacagat tgggatttgg ataaagattt
      661 aggtactact tattgggaag tcaaagtaaa agacggcaat caaagtacat cagtcaagat
      721 caatagccaa acaggcgaag tactgtcaac tgaacaagat gattaagaat ttcttcggaa
      781 aacaagagtt gatttttctt ttagtcatga tacactagac aaaataactt gtttgaagga
      841 gcgatttact tgagtttaga aacgaccttt gccaatcata tctttgccaa tcctttgatg
      901 aatgcatctg gtgtccactg catgactacc caggaattag atgaactggc tcattcagaa
      961 gcaggagcat ttatcactaa gagctgtacg atcaatgaac gaaaaggaaa tcccgaacca
     1021 cgctattttg atgttccttt agggagtatc aattctatgg gacttccaaa cttaggtttt
     1081 tcttattatc tagagtatgc tcttgcgtat gaaaaagtgc aggaaaacca aaatcaaccg
     1141 ttattttttt ccattgccgg gatgagtgtc caggaaaact tggaaatgct tgagaaaata
     1201 gaaaaaagtg ggtttaatgg gatcactgaa ttaaatttat cttgtcccaa tgtgcctgga
     1261 aaaccacaac tagcttacga ttttgaggcc acttatgaaa cactgaaaga agtattcagc
     1321 atcttttcta agccgctagg aatcaaattg cctccttatt ttgattttgc tcattttgat
     1381 cagatggctg atatcttgaa tcagtttcca ttgacctatg tcaatgctat caacagtgtg
     1441 ggcaatggtt tgtatatcga tacagaacaa gaagcagtag tcatcaaacc aaaagaaggg
     1501 ttcggcggca ttggcggaga gtatatcaag ccgactgctt tggcgaatgt tcgcgctttt
     1561 tatacacgtt tgaaaccaga aatccaaatc attggtacag gtgggattcg gacaggacaa
     1621 gatgcatttg aacatctgct atgtggcgca agcatgttac agattggtac cgagcttcat
     1681 aaagaagggc cggaaatttt ttctagaatc ataaaagaat taacgcagat tatgtcagaa
     1741 aaaggatata cgtcaattga cgaatttaaa ggcaaattac gcaccatttc atagcaaaga
     1801 gacgaaggtc atgattgatc ttcgtctttt tttataaaaa acactcgtct gttcattcct
     1861 gtgcaagcgt actcattgta tgttagacga acttgtggga aaataacaga ggcaaaaagg
     1921 aggataatat gaatgatgca acagaattag caaaagagct taaagaaaaa gaatttagtt
     1981 ttcaagaact agttacggat atacagaaaa aaataaagaa gcaaaatcat gaattgaatg
     2041 cgtttgtcgc gcttgaacca ttcgagagta attcccacga gctattgatt ccccagtcag
     2101 aaaaagggcc attggctggt atcccatttc ctttaaaaat gctcggtcaa gaaaaaaagg
     2161 gatggctagc tacttcagga tctcgtttat ttgaaacaca ccgagcttct catacatcta
     2221 attatgtgcg gcaagcagaa gcgataggtc tagttccttt tggacaaacc aatgcgccag
     2281 agtttggttt caaaaatatt acagacccag tcatctatgg cccagcaaga aacccttgga
     2341 accttgaatg tacaccgggc ggatcaagtg gaggagctgc tgctgcagtt tcatcaggaa
     2401 tcgttccttt agctggtgct agtgatggcg gtggttctat tagaataccc gcttcgtttt
     2461 gcggattgat tgggctgaaa ccttcgcgag ggacgatgcc agttggtcca tatgcttgga
     2521 gaggatggca aggagctgct attgatttcg gcttgacagt ttctatgaga gacacggagg
     2581 ctttatttta tgggatgaga agtatccatt ccggtgcgcc atatcaagta tcgccagttg
     2641 agtggcaaac acatccaaga aaaaaacggt tgaagatagc tttttgtgtt gattcaccga
     2701 tccactcaca gattagtgaa gaggcagtac ttgctgtaaa aaaagctgta gatttccttg
     2761 gaaaagaagg gcatgatttg acagagattc cttacccact agatggtcgt aaactgatca
     2821 cgtcttatta tcagatgaat ggcgcagaaa cagcagcaat gatccgctcg attgaaacag
     2881 gcatccagcg agctgtcaga aaagaagaac ttgaacccat ttcttggact ttgttccaat
     2941 atggtcagaa gctctctgcc gctacttaca tcgattctct gcatgtatgg gatgaagcag
     3001 caattgtcat ggaaaaccta catcaagaat acgatctatt cctttcacca acgactgcat
     3061 ttaccgcccc taaaatcagc gaagatttgc aaagtgatgc gataagagca cagatggaac
     3121 acatcagtga ttgttctgaa gtagaaggtt tagacgttgt ttcttccatg tttgaggaga
     3181 gcttgaagat cacaccttat acacagttgg ctaatctgac tggacaacca gcaatcagct
     3241 tgcctactca tttgacaaaa gaaaacatgc ctctaggaat ccaatttatg gctgccagag
     3301 gaagagaaga tttgctattt caaatcggct atctatttga agcaaatcat cagttccatt
     3361 taccaaatcc atggaaatag cagaaacaag gagaagaaga atgaagaaaa aaagattgtt
     3421 tgctctaata actagtgcct tttttatttt aagcgcttgc ggtacagctg ccgctaatca
     3481 ggaagataac agctggagta atgtagaaaa aaagaaagaa ttagtagtag cgacttctgg
     3541 cacactgttt cccgcatctt attataatga tcaaaatgaa ttagttggtt atgatgtaga
     3601 tttggcaaaa gaggtggcta aacggttaaa tgtcaaaatc tcctttaaag aatacaacgt
     3661 ggatggacaa atcacttctg tttcaaaaag agaatcagat tttgctgcga acgattttgg
     3721 tatcacaaaa gaaagagaaa aaaaattctc cctttcagag actttcaaat attcatttga
     3781 cagtatgatc gtacgaaaaa aagatgattc aggaatccac tcacttgaag atcttaaagg
     3841 gaaaaaagca gctggcgaac ccaatactag ctatatgcgt ttagcggaaa aacacggagc
     3901 taaattagtc acatatgaca atgccacgaa tgatcagtat ttaagcgatg tagcaaatgg
     3961 tcgaacagat gttattctaa atgattatta tctgcagaaa atggccgtat ctgctttacc
     4021 agatatccct gtaaaaatac tggagaacgt ttatttcaat gaaaacgaaa gtggtttttt
     4081 attgaaagaa ggaaatgatg ctctgaaaaa gaaaatcgat ggcgtattaa aagagatgaa
     4141 agaagatggg acgacaaaga aaatatctga aaaatatttt caaactgatg tttcagtcaa
     4201 accgaaagaa acgatggctg agtcggtgag tgagtgatgt actttcctct aattgatttt
     4261 tccctcatgt ggacttcact tcctttcgta ctgcaaggct tggtatacac attagggatt
     4321 ggcttcgtgt cgtttctttt aggaaatctg gtagggttgc ttttgacagt tttaggtctt
     4381 ttggattggc tgcctctgaa tgtatttatt cgtttttatt tatcgttctt tagaggcatt
     4441 cccgcactag tcctgctgtt tctgttatat tttgggttac cttatcaatt aagtgcctta
     4501 acggcttcag tcatctgctt tacgattacc agcagtgcat ttattggtga aatctatcga
     4561 ggatcactag caggcgtttc ttcaggtcag tgggacgctg gtttagcttc tggtttttct
     4621 ttctttgggg tattgaaata tatcgttttg ccgcaagctt ttcgaatctc agtaccggca
     4681 ctcagtaacg tagctatgga tctagtgaaa ggtacttcgt tagcagcaac aatcacagtg
     4741 ccagaaatat ttcaaaaagc aaagatcata ggcggtcgga cattcgatta tttttctctc
     4801 tatattttag ttgcactgat ttattgggtc atttgtatcg ggatcgaaaa agtgcaacag
     4861 tatttagaaa aacgttctat gcatcagtca atctgaaaaa tagaaatggt gctagcgtgg
     4921 ctggcaccat ttctattttt tgtttcttgt atattctgcc tagtatttta aaaccatttc
     4981 atgtaaaatg taaatcgaaa atatgttcgg aggtagaaaa catgaagacc ccgctaacca
     5041 tcgaaataga atcctcgtta taccaatatt gcatcgagca aggcggcttg gttgtagaag
     5101 aagtcacgat gcctgatgac caaggaattg tagatacgct tagctgcttg acaaaatttg
     5161 atggaagccg agaatggcga tgctatgagc tgaaagtgac aaaagcagat tttcgctcta
     5221 cagccaaact gtcatttgtt ggacattata attattttgt tttaccaagt aaactatatg
     5281 aagaagtaaa aactgaaatc cctacaggaa taggtgtttt agtgtatcgt ccgtacacgg
     5341 ttgaagagga gatgcctgcc tctggtacat ttctgattgc gaaaaaagca gcaaagaaag
     5401 agcttgctgt accggaagaa gctttgacaa accgcttcat ggcttcttta ttcagggaag
     5461 taagaaaagc aaagcaaatg gagcgaggcg taaaatattt tccaacagat caattgtaca
     5521 aagaattgaa aagacgttca gaaaatcaag atccattttc taacgaacga tattatgaac
     5581 ggtttttaga ggaaatagct agtcaggcaa tcaatgagtt gcaagaagaa gttatcgcgc
     5641 ttcagcatga ttatgaatat ttgaggcaac aacagcagat ccgtcggttg cctacagagc
     5701 cattggagtg aaaaatatgt actatcctta tttaagagga aaacaatttg acctattagc
     5761 attaaaagaa gcactgtcgc gaggattgct ctccaataaa atccaaccag tgatcgaacc
     5821 agtacgtgat tccgctacgc ttaaaaatgt gatcgaatta tttcaaaaaa agcaccatcg
     5881 aatcgctgtg atccaaaatc cccaagtagg acaattcaaa ttattcgatc agcatgtgca
     5941 cagttggaca gtcaaagaaa atagctctgt cgtccctgca cagatcttaa cgccagaaaa
     6001 tctcagtgaa gtactggatt cacctccagc gtttcttgtt ttcgatggac agcactaccc
     6061 aaaagataca gaggtgtgga aacagttggc aggagttgat tcgaaatttt tgataccaga
     6121 tactagtcgc tttcgcatct ggctgcccga aaacaaaatt gtgatccgtg actcttttca
     6181 aacgagaaag catgttgaaa gttatgcaga taaaacagat gactttttta gtgatgacta
     6241 tctttttttc cacgcagacg gatatattgg attttctgat ttcacgatcg aaggtagccg
     6301 ttatttcgat aaagggttcc ctagccgagc gcttgctatc catctaacgt atattgatgc
     6361 ttacggcaat atacgcgtga aacattttgt ctctgacagt aacgactctg ctaaagacca
     6421 agcattgaag tttcttgaag caggagataa aatgaaaaaa tggatcatgc gtcaccatca
     6481 tcaactcttg attacttcag gaatgattga attattggct ctttaccagc aacaaaaatt
     6541 ccctggactg ggagtgttga aaaagtggtc acttatgcat catttggaac ttattagtca
     6601 cctgctagat catccaaaag attggcttaa atattattca aaagttcagg aactatatga
     6661 agtgatccaa tgattagata atgtaaatga aaaaggaata gaaaagagga aactggatgt
     6721 atattcggca aacaaggaaa gaagaagtag aagaagtggt agaaatcatt aatgccgcag
     6781 cggatttcat tgcttcgcaa ggctctcctc aatggcaaaa cgggcagaaa ccaacaaaag
     6841 aaacgatttt gaacgatatt gaaagaaaag aaagctatgt attaatagtg gaagatcaaa
     6901 ttgctggaac agctgcatta gtctcaagcg tggatcccgt ttacacaaaa atagatggta
     6961 gttggaaaga atcaactggt ccttatttat cgattcatcg tgtcgcttta gcagaaagta
     7021 ctcgaggaaa aaaactagca aaaccgttct tagaacattt gttgacgatt gcagccagca
     7081 aaaatatcca agatatccgt atcgatactt atccagctaa tgaaccgatg gaaaagacca
     7141 tctattctgc tggattcact tatcaaggga tgattgaatt tccttttgaa cacggcgaaa
     7201 gaaaagcata tcaaataatc atcaattgac tataaaatca tctgagcaaa gataaagaca
     7261 ttaacactac tgaaaaaaac aatcatatga tagccaagag gttgtaacag aagtggccag
     7321 cttcaaaaaa caagaaagaa tttccgaaaa tgcttctcaa atttttgtgg aattttagcg
     7381 tattttacga aatagctgct ttctgaaact cccttcatcg agaggtcgtg acatagcttt
     7441 tgtcacgacc tctcggctta tcctacgagt attattcgat acatttatat caataatcct
     7501 ttttttattt tatctgcagc ttcttggaac gctccatcgt ttgacacgac taaaagtgag
     7561 gggatagctt tcaaacgttt caactgtgct aaatcttcta cataaaccgc cagtctggct
     7621 gaaatctgtt cagatgaatc tccacgtttt ttcaggcgcg attgcaatgt ttctttagag
     7681 atcgtaataa agataggacg gactaccgtc ccgaaatact catataaatg ccaaaaacca
     7741 tttgctgtca aaacggcgta acaatttcct actgtcagtt tctttttaat ttctgcttta
     7801 ctggaaccat atttatgttg agcatattgg tcccactctg caaactcatt tcccttgatc
     7861 atctgattga atgtattgtc agaaacaaaa taataatcct cttgatcttt ttccccaggt
     7921 cttggtgatc gattcgtgta agtaatgatc ttttgttccg gctgaaaaat agcttctgcg
     7981 agtgaagttt ttccagaacc agaaggaccg ataaatacat agcaataatt cattgtcatt
     8041 tctcctttga tgattgaaca agtgaaaaag ctttggaaaa tatttccaaa gcttttaaaa
     8101 gtaactttgc ttttttgtat attataccag caagccagtc acaatagcac ttaaaaagct
     8161 gactaaagtc gctgttagca aaattttcaa tccgtgtttt gcgacaagat ttcctttttc
     8221 ttcatttaat cccttcatcg caccagaaat gatcccgata gaagagaagt tggcaaatga
     8281 aacgaggaag acagatataa ttgctgttgt acgctcagta aaatggaaat taccatttgc
     8341 taattctgtc atagcaacaa attcatttgt aaccagttta gtcgccatga tactaccggc
     8401 atccactgct tctttccatg ggattccgct gatgaaggca agaggggcaa agatgtaacc
     8461 taggatctct tggaaagtga tgccgaatat cccgtggaag atagcattga tcatggcaat
     8521 caaagcaaca aaaccgataa gcatagcagc aaccgtgatc gccacatgga aaccatcaag
     8581 aatgtattct cccaacattt ggaaaaatgt ctgttctttg ttttcttcaa tgatcagctc
     8641 atcttctttt tcttctaata catagggatt tacaattgaa gccagaatat aaccgccaaa
     8701 taagttcaaa acaagggcag tgatcacata tttagaatcg atcagtgcca tataagatcc
     8761 gacgatcgac atagaaactg tagacatagc cgatacactc atggtgaaca aacgtttctc
     8821 agataggaag ggtaattcct tttttatgga aataaaaact tccgattgtc ctaaaatagc
     8881 agaagctact ccattataag attccaattt gcccatcccg ttgattttac ttaatcctag
     8941 accaacagct ttcataaata atggaagaat cttgatatag cgtagaatac cgataatagc
     9001 agaaataaat acaattggca tcaatacgga aagaaagaaa ggtgcacttc ctttatttgc
     9061 tacaccggca aaaacaaagt caacaccttg cccagcaaaa gcaagaagat gatcaaacat
     9121 ttttgccaat acagaaacaa ccgctgtacc aaaagttgta cgtaataata cgaaaccaag
     9181 aacaagctgt aaaacgaaca tcacaattag tggtttcaat ttgattgctt ttttgttact
     9241 gctgatcaaa aaagcaagcc ctaatgtgac aaataaacca ataataccta ataaataact
     9301 caaataatca ctcctattcc aaattccgtt ttattttacc tgttttgcaa ataaaatact
     9361 aatctttagt gaaattttca ttactttttt agagtgaaac gcattcattt tccattagaa
     9421 aataaagcga acaaaataaa aggtttaaaa agtgtaacgt cttagtaaag tctataaaaa
     9481 aacgaaacta tcgattaagc taatagtttc gttttcaaca tttataagta aactttttct
     9541 attggtaata tagattttcg gaagggtaga caggtgcgca ggtaatatcg attcctagtt
     9601 ttttcaatgt ttgttcatca tttttattga ccatcacagt agagtgggct tgtgctccct
     9661 caagttcagc tagtttatca taagcaactt gagcgattgg attcgttact gcactgattg
     9721 ataaagcgat caagacttca ttgatgctta gtgcatccaa agaggaatga agtgtctttg
     9781 atttcaatcc ttgtattgtt tcaagaacta atggtgacaa taaaggaatg tcatctgcga
     9841 tatgggctaa atgttttact gcatttaaga taactgccgc tgacgcatcc atcaatgaac
     9901 ttgtacgccc ggtaatgatg acttcatctg gtaattcgat tgcaatcaca gcagaaggat
     9961 cttttgtagg actttgcgct tgaatcttat ctgcatagtc atgggcaggg actaccacgt
    10021 ttcggtcttc aggacgtaaa ccgacttctt ccataatcag tttgattcga ttaactgctt
    10081 cttcgtcgat caatcctttt ttgaagtcgc attctgtttg gaaataacga cggatgattt
    10141 cttgtttaga ggcttcttgg acaacggtat catccacgat cccaaatcct acacgattca
    10201 cacccatgtc agtaggagat tgataaacag attctttacc agtaattttt tcaataatac
    10261 gtttgattac aggaaatgtc tcaacatccc gattatagtt cacagctact ttattgtagg
    10321 catcaaagtg gaaggaatcg atcatattga catcttttag atcgactgtg gctgcttcat
    10381 aagcaatgtt cagcggatgt ttcaacggaa cattccatac tgggaaagtt tcgaacttgg
    10441 agtaaccagc tgcatgtcct ttttggcttt catgatacag ttggttcaag gaagtagcga
    10501 gctttccact tcctgggcca ggagctgtca ctacaacgat tggtttagtt gtttcaatat
    10561 actcattttt tccaaaacca tcttctgaga cgattttttc tacgttgact ggatagtctt
    10621 cgatttctga gtgtttatag accttgatgt ttcgtctttc tagtttattg ataaagactt
    10681 tcgtggcagg ctgtccacta tagcgagtga taacgacact gttgattaat aagccataac
    10741 cacgtaattc atcgattaac cgcaagatat ccatatcata agtaatccca taatcaccac
    10801 ggatcttatt acgttcaata tctccagcat agacgcaaat cagtatttca gcttgatctt
    10861 tcaatttttg cagcaatttg attttcgcat cttcttcaaa tcctggaagt acacgtttcg
    10921 catgcttgtc gtcaactagc ttcccaccaa attctaaata taatttgtca tagtggttca
    10981 ctcgttccaa aatatacgct gactgctctt caatatattt ttctgaatca aaaccaattt
    11041 ttttcactag gttccctcct taagtactaa agcatttttt catttttttg aggattcgtc
    11101 aactggaaga gcgaaattcc tcaaaaaaac aaagaaaatg gtttaaacca acttgtctag
    11161 atagttattc attggtatga tagtttttga taaggaaggt gctacatgaa aaaaagacag
    11221 aaaaagaaaa acgcatataa acactatatc cgttcgattt ttaccggtta tgaaagaatg
    11281 cttgaagatc ccgaattgga acaattgacg tttacttatc taaacgaaga aacgcagcta
    11341 actcgtgatg agcatcagcg cattcatttc acaacaagag atctgcctag taaataaaaa
    11401 ataagataaa ggtcatcgga ttcgattctg tcctatcaga tggaaagact agttgatcga
    11461 aaaaaaggct gtaccaaatt ttggtgcagc ctgttttatg gagcattgcc cgctcttttt
    11521 tataacaatt ttttacagaa aatggtacta ttgaagtatt aataagtgaa aaacagatga
    11581 gtaagaggag gcaagtagta tgaaagagcc agatacaaat gcaaattatg agccagacga
    11641 actagaggag acgaatgcgg atcaggatac aggacaagaa tcgtcttctt tttacgatat
    11701 caaagaaaaa gcaagcatga atctttccca attattagaa gacttacagg cttttgaaaa
    11761 agctgtccgc gaagaagata tccctgagat ctaccgttta tacaatggcc gattgaatga
    11821 agaattaaaa agaagctcaa atgaaaatca cgagatcgat caattgctga tgcgtaagat
    11881 ccatgatcgt tttttacagg aatttccttt tatggaacaa gtagaaaaca tctcgccaac
    11941 gatgagctat tacaaaatcg gcacttatta ccatgatcgg cccacggtcg gtattgatgc
    12001 aagtctgcca gaaatttttg ttttgcctaa gatcgatgaa gagtgggaga aatattccca
    12061 accggagtca acggactatg acaaaaaaat caatgagcta gacgcaaagg tgatcactgc
    12121 tcagacagaa attgaacgtt tagatgaaca aataaaagaa atcaatcgac aaatgactga
    12181 tttgaacgac aataaaggat tcttgaatcg taaaaaaatc gaggaagaaa ttcaagaatt
    12241 agagaagaag aagcaagtac tatctaatga aaaattaggc tggcttcctt atattgagac
    12301 gcctgaaaca atccagcagc aaaaagaagc attgaagcaa gaagcaagag cagaccagct
    12361 tcgtgcagcc atcgtagaaa aagaacaaag gcaaatcaga cgctatttcg gtagcaaaga
    12421 gggattcggt caagcaatcc atgaattctt gatgaattat cttggcaatg agaatcctaa
    12481 taatcaatct aatgaaggag gttccgagta tgaatgaaca cgatgaagca gaatggacaa
    12541 aaaatgaaga acaaacagaa gatcatgaag aaacgaacac ttcattggaa gaacaaacaa
    12601 gtaatcctct ggatgacaca gaagaaatcc ctatgctaga ggaaacaaaa atacacgaaa
    12661 aagaaaaagt aactccgacg aatacgaata ctgcagaaaa cacccatgct tacgaaataa
    12721 ctgaaaatcc cgggtattta gaaggaaaag agcaagatca tcaagatatc gtcagtttga
    12781 ttgaaacagc ggaagcagaa ttagcggatt tacgtatgag aaaagatttg atcgaatcag
    12841 attttccaca attattagaa tcatatgatc gttttatatt gaatgaagaa ccaatctcca
    12901 cgatcggaaa gacaagcctg atcgaatact tcacgtatga attactgaaa ccgttgaatg
    12961 atattggtct ggaacggtca aattcagctt atgacacatg gaaaacaaga catttttcga
    13021 tcaattatac gttgaatgga caaaacgaat tagtcttttc ctttgtatta ccgaccatcg
    13081 atcaacgata ccaagtggaa tcgatgagtc tcctaaacgt atcaccagag acaatggaaa
    13141 tcaatgtcca agatgaccgg gtgctttctt tgatccgaca ctggtcagtg gatcgagtat
    13201 tctctgcagg gcagatcacg atattcaatc acaaattgaa tcaattatta gcccatgcaa
    13261 gaacacttgg ttttaccgtt aatcagacat tactagacaa tacgaagcca cttcgtttga
    13321 atcttcagag cgaatttgaa ttgacgaatg aagtattgga tgatattttt atcgtggcaa
    13381 tgaaaaatcc atcctacgat atggaaaaga tcaacgaaac tacttatcaa gtacgattag
    13441 ataaaggaca gtctttaacg ataacaacaa acgaaaaaga tcaaacagtc ttgtcgatct
    13501 catctggaga ctacccacga tctgtcattg atttctttat caattacgaa ttcttggtcc
    13561 cattaatggt gagaaagtcc tgattggata agttggatta ccagatgtca ttcagataat
    13621 tctgttccaa aggacttgcg gcagttatcc agaataattg tcacaagtct tttctgtatg
    13681 tactaaatgg acgtgaataa cttgctgatg aaggagggat ttcattagga atgtccacaa
    13741 ataaaatagc acagcttagc ttattgtctg ctgcttgtgt agcaggtagg atcgcttttc
    13801 aatttattcc gaatttccag ccaatgactg ctattttttt atttatagta ctttacttaa
    13861 gcttaaaaga tgcgttaatt gtcatgagtc tttctattgc gatcagcagt ttttattttg
    13921 gtgttggacc atgggtcatc ggccaatgga tcagctatac tgttgttctg agtttgtttt
    13981 caatcgtctg cttgagaaaa acagtgcaaa ggaatctatg gttaaaggga gtctgttttt
    14041 ttctggcggg catggtttac ggaataggta tgaccgtttt tgatacgctg ttatatcgtt
    14101 tgcctcaacc ttggatctat taccttcaag gggtgtcgtt tgatttgatg cacagtatag
    14161 gcaatgttgt gttctttctt gtttttctgc cagtcgtcaa acgtttttac aatcattcag
    14221 gaggaaaaaa tgaaaaaaat aatttatagt ttgcttgcaa tgagtgtcag tatactcatt
    14281 ttgacaagtt gcagtacaac ctatacacaa tcggcttcca accaaaagga ggaagtaaaa
    14341 acatcgcaaa aagcaacaat cacgttacaa gaaaatggtc aaaacttttc ggaaaaagaa
    14401 gtgttcttca aaaaaggcga tgatttactg agtattttga aacgaaattt tgaagtcaaa
    14461 gaagataacg gcttcatcac ttcgcttgaa gggcactcac aggatgagaa aaatcaactc
    14521 tattggatgt ttactgtgga cgggaaaagt gctactactg gtgccaaaga gatcaaattg
    14581 aatgatggac aatcggtcat tttcaatttg tctaaactat aagtttcata aaaaactgtt
    14641 aaagggcgaa tattgccata attcagtgag ttcagttgat gaaagaagga aaataacatg
    14701 gaaaatttta aaaaaagcgg aatgttttcc gtaattgctg ctctaggggc taatattcta
    14761 gttgctatca gcaaatttgt cggctatgca atcagtggca gtgccgccat gctaaacgaa
    14821 agcatccaca gtatcgttga ttgcagcaat cagattttgc tgttattcgg tgataaacaa
    14881 gccaataaag gacagagcga gttgcatcaa tttggtgaag gacgagcaaa atactttttc
    14941 agtacaatcg tcgcaatgat gcttttcttc ggcggtgggg cacttggggt gatggaagct
    15001 tttgaaaagt tgacgcatcc atcccatgaa gtgggtaatc cgatcattgt tatagcaata
    15061 ctgttatttg gtttggtaat cgaaggaagt tcgttacgcg tggcaatgaa agaaatcaaa
    15121 gaattgaata ctgaaaaact ttccacgatg cgctttttgc gcgaaagtcg acacagtgaa
    15181 atactgatta tttttacgga agacttgtgt gctgtaatcg gtttggtctt ggctttagca
    15241 ggaacaatat tgacttatgc aaccgggatt gctgcatttg atgcgatcag cggattgctg
    15301 atcggtttct tgctgatggg agccgccatt ttcctagcaa aagaatttta tagtctgatc
    15361 atcggtgaaa gcgtgacagc aagcgattta tcaaaaatca agttagcttt tgaacgtcct
    15421 gagatcagtc ggctgatcga tataaaaaca gttcatttaa gtccaacgga gattttagtt
    15481 gcagcaaaag cagatatcgt tggtaacaaa gagaatgaag cttactcggt catcaatgat
    15541 attgaaaaaa atatgcgtca gtctcttcct gacaagaaga tgtatatata cattgaaaca
    15601 gataaatatg acccaaatta ttctcgtaaa taaaacgttt attcatgaat tgaagcaaaa
    15661 atgagaaaaa tataatcttg tttttaaata aaacggctac aatttagcga atttatgtta
    15721 caatgagtcc gctgtttatt tgttgtaatt aaaggagata ttttaatgaa caaaaagaaa
    15781 agtgcgccat ggcttcaagc tttgcatgca gtgatgccac tttgtataag ctatatacca
    15841 gtaggattag cttgcggagt attgttgcaa aaagttggat ttgatcctct cttatcagga
    15901 ctgttatcga ttctggtctt ttccggtggc gcgcagtttt tagttgcatc tatgcttacg
    15961 acgcaagcat catttgcaac gacattattg atggttttct ttttagaatt acgctataca
    16021 ttattaggag caagtcttgc cggttttatg aaaaaagaaa agcggacgtt tttggctgtc
    16081 ttttctcaat cactgaatga tgaaaactat gcggtgaact acttaaagtt ttcaactgac
    16141 ccttcctgga ataaaagaaa ggctttatat gtcaattggt tctcaatgac tgcatgggcc
    16201 ggtagcaata tgatcggtaa ttttttcggc tcggtgattc gagtagatgc tgaccttgtc
    16261 cattttgctt tgacggccat gttcattttc atgtttatca tgcagatgaa aagcgcacta
    16321 ctgatcttta caggtttatt ctcaggcgta ttaggggtcg tattcatggt attattccaa
    16381 aatactttcg gattgattgc agcaacagtc attgcttcat ttgccggatt tatgctggag
    16441 aaggcattca aaaaagaaaa agctaagaaa ctaagagacc gcggtaaaga tgtcaatgag
    16501 ccgctcttca acttcccgga acaggaggcc aatcaccatg actaaactat atttgctact
    16561 tttagttgtt tgtctgttca tcgtggcata tatcccgcgc ttgttcccga tgctttattt
    16621 tactcatcga aaagtgccat cctggttcag tgactggatg aaatatgtac cggtggcatt
    16681 atttgcggcg ttagctttta aagatgtttt cattactcat gaacatctgg atattgcttg
    16741 gaatatcaaa atagctgcaa tgattctagt agcaggcgtg gcttacaaaa cacgttcgat
    16801 ggcgttgtca gttttgacag gacttgcgtc tgtctttttg ctgtctatgc tttaaactgt
    16861 tttattttat taaaaacaga gattgcgaca taagttgttc aaactgatct atccgaactg
    16921 catttgcaac agtcaattct ggatgcaagt ttattcgtag ggataaaaaa gattagtgtt
    16981 ggcttatgat gcaagctctt ttttatttta ggaattagag agggatttgt ccttctatga
    17041 ttttttgcta taatagggaa gatgtttatt ttatgaaaga atagttgagg gaatttaaat
    17101 gaataaaaaa ttgatgcaag gaacattttg gctaaccttt gctaatcttc tatgtaaagt
    17161 tttaggggta gtctatttga ttccctggct aagtatgatg gggaacaatc aagatggtat
    17221 gcttgctacg acattgtata atgttggcta tcttccttat ggattgttcc tgatgcttgg
    17281 tacagtcgga tttccaaatg cgattgcaaa aaaagtagct gtagccacaa aagaaggaga
    17341 taacgctgct tgtcggctga tttttagaag tacgatcaat atcatgtttg tcatcggtat
    17401 cgcctctgct gcactgatgt atttatttgc tcctttacta gccggaatca gtccgattgc
    17461 taacgttaat aatgggatac tagctatcag aagtttatgc ccatctttga ttgctatccc
    17521 aattcttagt gcaatgagag gatatttcca aggaaaaaat gatctgcggc cttatggaac
    17581 ttctttgatt atcgaacagg ctgtgcgagt gatcgttatc ttggctggta cttattactt
    17641 gcgcgtattg actgacggaa ccatattaga agctgtattg atcagtacag tcgcttcttt
    17701 cttcggtggg ttagctgcga ttatccatat gtatatcgtc ggacgcagaa aagacttctt
    17761 cgaacttaaa gattttttga tttccagccg ttatttcgaa agagaaaacc gatctgcctc
    17821 tgtctctatc attcgggaaa cactaccgtt tatttttgtc ggctcagtca ttactatcgt
    17881 tcaaatgatc gaccaagtaa cgatgaaacc actgcttcac tttttccgtc cagagatcgc
    17941 agatcagcaa ctggaattct tattcagccg tgcttctgtc aatccaaata aattgacatt
    18001 gatcctgatc tccatggtag gaacagtagc tataagcagc ttgccaatat taagcacgat
    18061 gaagaaaaaa gatcggatac aaatcgaaaa aacagtagga gatagttttt cgattgcgtt
    18121 attgattctt cttccttcat tgactggaat gtctttatta gctggaccac tatacacatt
    18181 gttttttggc tatgatcctg aaagtgtcgg atatttccaa atggctttgc tagcttcttt
    18241 gtttttctct ttattcacga tcctatctac gatgcttcaa tctttgaatc accatcgttt
    18301 tgcgatccga ttaactgtag aagcaattat cctgaaagtc atcttccaag taatcggatt
    18361 aggattagtt ggcggatacg ggatgagctt atcaaatggc ttagcattcg gtattgtctt
    18421 tgttcgcggc tatcacttta tgtgcaaaga ataccgaata gcacctttag caaagatcag
    18481 caattttttc ttaaaaactt tccgctccac cctgattatg cttgcagtat gttttgccgt
    18541 tttctttttg ctgaatcagc gattgtcaat ggaatcaaaa agctatgcaa tgatttattg
    18601 tgtggctgta ggaagtattg gcggcttagt atttttattt tctcaattcg gaaaaaatgg
    18661 gtttcgaatg ttgaaaaatg ttaaacatca tagcagaagc aaagaatagg ttaactaatc
    18721 gttttttgct gtcacttgaa aaacggcaac tcgtatgatt acgcttgtcg tttttctatt
    18781 ttccaatttt agtttcatat ctaatcttac ttatgatata gttataaggt ctggaaaaat
    18841 tctttgaaac gaggaaatta aacacatgaa acttgcagta gttacagata gttcggcata
    18901 tctgccggaa cgtatcaaga accatcccga cttattcgtt attccaatcc ctttgattat
    18961 ggatgggaaa atttataacg aaggaatcga tatcgaagcg gatgaatatt atggactttt
    19021 aaaaaacagt aaagattttc ctactacttc acaacctgtc gtaggggaag ttttgggttt
    19081 atatgaggaa ttgaaagaga aagggtatga cacgatttta agtatccatc tttcttcagg
    19141 gatttctggc tttgtcaaca cattatttgc gatgaaagat gacatcagcg gagtaacggt
    19201 cattccttat gactctaaga tcactagtat gccgatggga cacatggtag aagctgcctt
    19261 agacttaaat gatgaaggtc agtcccttga tgaaatactt gcacatatcg atcgaatccg
    19321 agataatacc tacgcttatc tgattgtaga tgatttgaac aatttagtac gaggaggacg
    19381 tttgacaaat ggtgcagcgc tgattggcag cttattaaaa atcaaaccga tcctgacatt
    19441 ttctgaaggg aaaattgttt tattcgaaaa aatccgttca agtaaaaaag catttgctcg
    19501 agctgaagaa attattggta gaagaaataa cgaaatacaa ccgccagtca aactttacgt
    19561 gatacatgca aataatttag aagtagcgat tgcggagaaa gagaaattgc agaaaaaata
    19621 tccaaatgca gaaatcgaaa ttggtcattt cggaccagtc attggtacac atttaggtga
    19681 aaaagccatc ggcattgcca tttcagcgca ataattcctt ttattcaaaa aacataccaa
    19741 aaatattcca acatcatctt ggactttcta catgttacta atgagcgtgt aaaagaacga
    19801 gatggtgttt ttatttctat caatgaagct ctttttcttt gcaatcctca cttcaatcct
    19861 ctataatgtc gcatatagtt tagtaaatga gtaaactact aatttactta tttactaaaa
    19921 ataaaaggat gaggagttaa aataatggaa ataccaacaa atttaaaaca taaaccagta
    19981 atcgttgtag aagactatga taaagttgat ggaagaaatg cattaaatac ggatgcaaaa
    20041 gggctttcac tgggccttgc tcagtggaat gatcgtggaa aagtcgatat ctcaggcaag
    20101 gtatggcgac atactggaga aaaatggtca cgacagtcgg aagaattacc aatcacacgt
    20161 attttagatt tagcgatctt agctgcacaa ggaagtttat acttccaaga tgcttatcgt
    20221 tatgaaaaat tttatgatcc agaaaatcca gtcgtagaca tcattggatt acaagggaac
    20281 cgaatgacgg tagaagtaga taccaaaaat ccaaagatcg atgaagacat cattttgtat
    20341 tacgatacac tacaaaaaga cggagaactg attggggaac gattccgtat tttaaaacgt
    20401 cttttagatg agctaggata ttaatagaca gagatgatca aaaggggaag agaagcatgg
    20461 agaatttctc actaacagaa aaccgaacct tttcacggct agaaaagcaa atgatctgga
    20521 agaaaccgaa aagccatcgg acaagtgcag aagaatggcg gatcgcctcc gaaatcaaag
    20581 ggaattggca agatcctgaa atgaaaatca gtaacgtact tttggaagga gatgccgggt
    20641 cggggaagac acaattagcc aaagcactat ctgctgatct gcaacttccc tatacaaaag
    20701 tgacctgttt tgcagatatg gacaaatcag atgttttcgg agccttatta cctgtagtag
    20761 attctaataa ggaacaagac caagaattac tagaagctat ttaccaaaca gatacacttg
    20821 aagctgtact gacactgatc cagaaccatt acggcattga tcctttttct gctaaagaaa
    20881 aattagcaga gctagttcaa aggatcgaag ctgattatcc agatgcaatc cattacagct
    20941 attacccttc tgaaatcgtt cgagcgattg aaaaaggata tttattagag attcaagagc
    21001 cgactgtcat ccgagatgcc tctgttcttg tggcacttaa ctcagcgctc gaaccaaatg
    21061 ggatgttgaa tttaccgaca ggaatcattc gtcgccatcc agattgcgtc attgtgatca
    21121 ctacaaatcg aaattaccaa ggaaatcgcc cattaaatga atctttaaga gatcggatgc
    21181 aacatgcgga aaaaatggat cttcctgcct tagaagtcat ggcagaacgt gcgatggcga
    21241 aaactatgat ccaaaaacaa gaacttctct taaagatggc agagattatc cgtttgttgg
    21301 atgaaactgc aaaagctaac gccatcaaag gtgtagcagg aatgcgttct tatttttatt
    21361 gggcaaatac ctataagcaa ggacaagatt tactccagtc gatttatcca aaagttttgt
    21421 ataaattatc cactgattca gatgaattgg caattcttga acaagctttg tctgacagtg
    21481 gattgctact ggaacttcag gacatattga gaaaagaaaa atggggtcat cctcaatctg
    21541 agcatacaaa aggaagaacc attagcgccg aagaagcaaa tgaacgaaac atcactgaaa
    21601 atgctgaaga aattctgcgc ttagatgaaa agaaatcgtt gtctgctgaa gaaccaaatg
    21661 agggagaaga gaaacaagaa gaaacaatag aaaaaaacga gattcctcct caaatgcaaa
    21721 aagaacgcag tagcgatatc gaaggaaaaa atcaaaaaga acaacaaaca ggagatgatt
    21781 ctcaagaaat gtctgcttct gacatggaag cacatgataa ggaaatcaag aagcaactga
    21841 ataaagaagc gcgacaaatc atgaaggaaa cgattcatga aaaagaaggt ctcatcgttc
    21901 accgaccagc tttccaagga aaaacgccgg aagcacgtga gctacacatg caagtaatgc
    21961 caatagtaga atcacttagc cggcaaattt tagagttact ggataatgaa caaacagaga
    22021 cgtaccaaaa aggaaaatac gaaggtcagc ggttcaatgc aagcaaagta gcatatggtg
    22081 atttgagaaa ttttgacaaa aagaacccgc cacatgagca accttcttta gcggtagctg
    22141 tacggatcga tgaatctggg tcaatgatac gggatgatcg gatcgaagcg gcaaaaaaag
    22201 cagcgattgc cattgccgaa ttttctaaga aagtcgatat cccattgttg atttacggag
    22261 atacagcaga ccgttcgtca agagaaaaga cttctttgtt ttcttataaa gaatttgaag
    22321 acggatttca atggttaaat gaaaaattag tcactatgaa accaaggcaa aacaatcgtg
    22381 atggtgctgc acttcgttta gcagcagaaa aattaaacag acaatccgca acaaccaaac
    22441 tgttgcttaa tattagtgac ggtcagccaa aagcgttgcc ggattataca ggcaaaaaag
    22501 caaaagaaga tatccagtct gttttgaaag aatatgaacg tcaaggaatc ctatttgtct
    22561 ccgcagctat tggccaagac aaagaagaaa tcaagtcgat ctacggtgaa agtcgttttg
    22621 tagatattac tgacttgaat gaatttccca agcaaatgat tcaactgatt gcccgctatc
    22681 tatgataaaa taaagctcaa cgaacgcact tagcagattc gttgagcttt tcgtttctag
    22741 ttaccggtaa caaggatact tctaaaatag aatcggttat aatcaagagg gaccgttaaa
    22801 ggagtgaaac gatatgatac aagaacaaaa atggtggaaa gaagcagtag gctatcaaat
    22861 ctatcctgct agtttcaaag atagcaatgg cgatggtcaa ggagacatca atgggatccg
    22921 tgaaaaactt aattatttga aagatcttgg tatcggcttt atctggatca atccgatcta
    22981 tcaatctcca tttgtcgata atggttatga cgtaagtgac tatcaagata tagaagagag
    23041 attcggaacg atggaagatt ttgatttatt gctaaaagaa gcacatgaat tagggatcaa
    23101 agtgattatg gatcttgtca tcaaccatag ttcggatcag catcaatggt ttgaagaatc
    23161 gaaaaaatct aaagaaagcc cgtatcgcga ttattacatt tgggtcgacg gggtagatgg
    23221 caaagaaccg aataattgga catcgatttt cggcggttct gcttgggagt attctcatga
    23281 aactggacag tattatctgc atgtttttgc aaaagaacaa ccagacttaa attgggaaag
    23341 cgagaaattg aaagaagaac tattcaatat gatccgatgg tggttggata aagggataga
    23401 tggatttcgt ttagatgcga tttctcatgt aaaaaaagat gaatattcag taaaagccac
    23461 agagaaccct ttctcaccct ttcaaaatgt ctcaggaatc gaagaacatt tgaccgattt
    23521 gaaacatgtt tttgaagagt acgatatcat gactgtcgga gaagcaagtg gtgtcactgc
    23581 agaagaagga ccacaatggg tagggaaaga cggttatttc gatatgatat tcgaatttga
    23641 tcatatccat atctggcagc aagaaaaaga agggcaatta gatgtcctta aattgaaact
    23701 tgcattaagc gcttggcaaa cttcattgga tggtatcgga tggaacgctt tatatatgga
    23761 aaaccatgat gttcctcgtg ccgtttcagt gtttggagat actcgtcccg atttttgggc
    23821 tatgtctgca aaagcaatcg ctatgatgta tttctttttg caaggtacgc catttattta
    23881 tcaaggacag gaaatcggaa tgacgaatat gccctttgaa tcgatcgatc aagttgatgc
    23941 agtagattcg aaaagacttt ataaaaggct gcttgcggaa ggtaagacaa gagaagaagc
    24001 attggatatc attcgtgaaa caacgagaga caacagcagg acacccatgc aatggacttc
    24061 ggaacaatat gctggttttt ctacacatga accttggctg atcactaatc caaataccaa
    24121 aacgatcaat gtagaacaac aagaatatga accagagtcg gtcctgcaat tctataagaa
    24181 catgatccgc attagacaaa ccaataaagg tctgatatac ggttcttata aagaatatct
    24241 tcatgaacat ccacaacttt atgtctatga aagatattta gaagatgaac aatatcttat
    24301 tatggtaaac ttaacagaat cacttgctga ctatgaactt ccaaaagaag cagatcagtc
    24361 ctggacatta ctcttgtcaa attcctctag cggagaattt gaagctaaag gcatactagc
    24421 accttatgaa gctcggttat ataaaataaa caagtaaaac ttcctcgtta aagttcatta
    24481 gttggacttt gcgaggaagt ttttcagatt gctctgtcaa ttactcattt caataattcg
    24541 ctctaggacc accgatatat ttaggacgag agcgaagggc tgtcacgtga gcttgtccaa
    24601 gggttttcaa acgaggtctg acaggtactt ggacatgttt gatatgcata ccgattgatg
    24661 tgtcaccgat atcgataccg gcttgtccaa ctacgtgttc cacttcgaca ggatcattga
    24721 actggtcaaa agcagcaaca gaacaagcac ctccagcatg tagtgcagga acaacagaga
    24781 caatttcgaa attttttgct tctgccactg ttcgttctac tactaatgct cggttcaaat
    24841 gttcacaacc ttggacagct agcgcaattt ctttaggatc caacaactct tttaacgtac
    24901 ggatgatcca ttgaccaact tccgcactgg aattttttcc aatatgtcct ccaacgactt
    24961 cgcttgtgct gcatcctaaa acaaaaagat cacctttttt caagtgtgcc tcagccaata
    25021 tgtcattaac tatttcagtc aattggtctt ttaattcttt ttctgacaac ttcattttct
    25081 aaaaccttct ttttcaatta atattgcttc cgtgcttgaa tacgttgaag acttgcagtt
    25141 ataggaaagg caagtcccat tccaatcaga ttttggaaga tgtttcctgg tatagaagcc
    25201 actccagccg gccaatcata taaaatccaa ccggcgatac catagccgat gatcataact
    25261 aagcttccta ataaaagccc taatccccac atacgagtag aagatttgct gaaagaacca
    25321 gcaacatatc cttgtaaccc gtggatcact aatgaaaaaa ctgcccactg cggatatcct
    25381 gaaatcaaat cgatcaatag accactggaa gcaccaacaa ctaatccacc cgttggacca
    25441 taaagaaaag cagcggtata gatcccggcc tcgcataatg tcacaaatcc attcgtagcc
    25501 ggtacaggga tcaaaattgt taatgaaagg gcaactgtca acgcaatcag catagcatag
    25561 atcgttaatt gcttagtttt catttctcat tcctcctttt tgaataccgc cagaccagac
    25621 acttccggta tgatcgttca tcagcacgcc attagaaata caatgggcaa caaatttttt
    25681 actttctgct actgctttgg taaaatctgc ccctaacaca agattcgctg ttattgcaga
    25741 agaaaaggca caaccggccc cgtttactgt tgtagtgtcg atttttttat gagaaaatac
    25801 ctcataatga tcaattgaat agagaagatc cacagcttca tctccagcca tccttgtgcc
    25861 gcctttgatc acaatgtttt ttgttcctga agcagtgagt tctttagcga gatggatcat
    25921 ttctgttaac gaagagggaa gagcttgacc agaaagtaaa gcagcttctg ccaaattagg
    25981 cgtaatcatc gtaacaagtg gaaaaagttc ttcgatgagc tgcgaaatat acaattgatt
    26041 gatcacagct tcagtttctt tgaatgccaa aacagggtct aaaatgattg ggatattttg
    26101 ttttgttttt atgaagtctc gaacaaccat gattgcttca cttgaattca ataacccaat
    26161 tttgatacca tctaatgaag tcattttatc aatcgaaact aactgtcgtt taagcaattc
    26221 caaagatata gattccagca taaatcgctc attaatatct agtgccccta tagaagtcaa
    26281 ggcgcttagt ccgaatagac caaaattctc aaaagttttt aaatctgttt ggattcctcc
    26341 accagcaaat ggatcagaac cgccaattgt caagattctt ttcataacat tttcctccat
    26401 gaataagagt ataacgaaat tttcaaaaaa gaaaaacagc caattggcat atttttatct
    26461 catccaattt aaaaaaacaa aaagaaaaga aagaccaaaa tggatctttc tttccttaaa
    26521 tagttaggac ttttgtgatt ttaattcttt ctcgatttga agccgttgca ctttcattgt
    26581 agctgttcgc gggattgcat caaaatcacg gatgataggg acgttcaagc gaggaagttc
    26641 atggacttgc tcccaccatc gattccaatc catttcttta tcaggagcta aagcaataat
    26701 cggttgtgga gaatgatttt tatcccttac aatcactact tctgccaaaa aatctaacga
    26761 atctaataaa aagtcttcaa tagctaatgt actattgatc gtttcgatca aatccacttg
    26821 ccgatctttc aaaaataggt ggccatgctt atccataaaa ccgtaatctc cgctatccca
    26881 ccaatcgcca taaacatttt cctggaaccg tgcatcttcc ttgtaataag tcaaagcccg
    26941 tcctttagac agtaattgta tatgaccatc tgtgttttca ggtaggacat tcccaactga
    27001 atctgtaatc cgagcgcttg tcatgtcttc cagtccaacg cccatatctc ttgcatcact
    27061 tgttttcaaa ctctctagtg tatgagcctt aagaatcatt ggtccgcatt cactttggcc
    27121 atatacttga agaaataccg catcctgtgc catcgacgtt cgcaaaaatg tcttcattgt
    27181 ctggttgttt atagcatcaa aagtggagtg atagtatcgg atacccgaaa aagcttctgg
    27241 atgctcctta gcagtaaaac gccactgaac aaagttattc ggatgggtct ctagtgcaat
    27301 tggccggtga gcttccaaca tatgaacaac ttttgaactt tgtgcgtttg ctaaaggcat
    27361 cataggaaat cccatggaca tcaaagaaga gataccaata ttgaatctgg aatgcactgg
    27421 agagatgtga aaagcgatta atttcttttc cgaaattttt gtgaaaactg ttttttgcca
    27481 tttcgtccgc catcccatag aatgagcaga atgacaaata agtttaggga taccagttgt
    27541 accagaagta tgggtcatat aagaaatttc atttttgtct aaaaatgatt gagaaacaga
    27601 caaagcaggt tgttccatta aataaagaat agg
//
LOCUS       DAFEIE010000032        27569 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFEIE010000032
VERSION     DAFEIE010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.033"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(81..1028)
                     /gene="arcC"
                     /locus_tag="LP345_001572"
     CDS             complement(81..1028)
                     /gene="arcC"
                     /locus_tag="LP345_001572"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL1760357.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(1143..2162)
                     /gene="argF"
                     /locus_tag="LP345_001573"
     CDS             complement(1143..2162)
                     /gene="argF"
                     /locus_tag="LP345_001573"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBL1760358.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(2253..3482)
                     /gene="arcA"
                     /locus_tag="LP345_001574"
     CDS             complement(2253..3482)
                     /gene="arcA"
                     /locus_tag="LP345_001574"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBL1760359.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            3943..4644
                     /locus_tag="LP345_001575"
     CDS             3943..4644
                     /locus_tag="LP345_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL1760360.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(5253..6269)
                     /gene="tsaD"
                     /locus_tag="LP345_001576"
     CDS             complement(5253..6269)
                     /gene="tsaD"
                     /locus_tag="LP345_001576"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBL1760361.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(6266..6730)
                     /gene="rimI"
                     /locus_tag="LP345_001577"
     CDS             complement(6266..6730)
                     /gene="rimI"
                     /locus_tag="LP345_001577"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL1760362.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(6737..7279)
                     /gene="rimI"
                     /locus_tag="LP345_001578"
     CDS             complement(6737..7279)
                     /gene="rimI"
                     /locus_tag="LP345_001578"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL1760363.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(7263..7985)
                     /gene="tsaB"
                     /locus_tag="LP345_001579"
     CDS             complement(7263..7985)
                     /gene="tsaB"
                     /locus_tag="LP345_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBL1760364.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(8176..9156)
                     /locus_tag="LP345_001580"
     CDS             complement(8176..9156)
                     /locus_tag="LP345_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1760365.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(9180..10664)
                     /gene="galT"
                     /locus_tag="LP345_001581"
     CDS             complement(9180..10664)
                     /gene="galT"
                     /locus_tag="LP345_001581"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBL1760366.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(10676..11665)
                     /gene="galE"
                     /locus_tag="LP345_001582"
     CDS             complement(10676..11665)
                     /gene="galE"
                     /locus_tag="LP345_001582"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBL1760367.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            11913..12080
                     /locus_tag="LP345_001583"
     CDS             11913..12080
                     /locus_tag="LP345_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBL1760368.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(12142..13953)
                     /locus_tag="LP345_001584"
     CDS             complement(12142..13953)
                     /locus_tag="LP345_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBL1760369.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTNENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(13950..14315)
                     /locus_tag="LP345_001585"
     CDS             complement(13950..14315)
                     /locus_tag="LP345_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBL1760370.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(14478..14873)
                     /locus_tag="LP345_001586"
     CDS             complement(14478..14873)
                     /locus_tag="LP345_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL1760371.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(14891..15853)
                     /locus_tag="LP345_001587"
     CDS             complement(14891..15853)
                     /locus_tag="LP345_001587"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBL1760372.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(15853..16065)
                     /locus_tag="LP345_001588"
     CDS             complement(15853..16065)
                     /locus_tag="LP345_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBL1760373.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(16086..16784)
                     /locus_tag="LP345_001589"
     CDS             complement(16086..16784)
                     /locus_tag="LP345_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBL1760374.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(16804..17346)
                     /locus_tag="LP345_001590"
     CDS             complement(16804..17346)
                     /locus_tag="LP345_001590"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBL1760375.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(17478..18482)
                     /locus_tag="LP345_001591"
     CDS             complement(17478..18482)
                     /locus_tag="LP345_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL1760376.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(18479..19468)
                     /locus_tag="LP345_001592"
     CDS             complement(18479..19468)
                     /locus_tag="LP345_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL1760377.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(19465..20271)
                     /locus_tag="LP345_001593"
     CDS             complement(19465..20271)
                     /locus_tag="LP345_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760378.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            20437..21393
                     /locus_tag="LP345_001594"
     CDS             20437..21393
                     /locus_tag="LP345_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1760379.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(21470..21988)
                     /locus_tag="LP345_001595"
     CDS             complement(21470..21988)
                     /locus_tag="LP345_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1760380.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(22076..22225)
                     /gene="rpmG"
                     /locus_tag="LP345_001596"
     CDS             complement(22076..22225)
                     /gene="rpmG"
                     /locus_tag="LP345_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL1760381.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            22453..22899
                     /locus_tag="LP345_001597"
     CDS             22453..22899
                     /locus_tag="LP345_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL1760382.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(23094..24989)
                     /gene="asnB"
                     /locus_tag="LP345_001598"
     CDS             complement(23094..24989)
                     /gene="asnB"
                     /locus_tag="LP345_001598"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBL1760383.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNETIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(25314..26288)
                     /gene="bsh"
                     /locus_tag="LP345_001599"
     CDS             complement(25314..26288)
                     /gene="bsh"
                     /locus_tag="LP345_001599"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBL1760384.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            26937..27239
                     /locus_tag="LP345_001600"
     CDS             26937..27239
                     /locus_tag="LP345_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760385.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT         8250 a         5732 c         4716 g         8871 t
ORIGIN      
        1 aaaatccaga tggcctaaag gagaagaaat accacctgga tagctataaa tcatttcgta
       61 aatacgaaag acttaacaaa ttaatcagct acgataatcg ttccttcttc agaagctaaa
      121 agattctcga tattttctaa agaagtgatg attgccttag cgtttggttt tgcttcaaca
      181 aatgcaatag ctgcttctac tttcggaagc atgcttcctg gagcgaattg cttttcatca
      241 atgtattgtt tcatttctga aacagtaaca gtttctaatt tcttttgatc tggtttttgg
      301 taattgacat acacattgtc tactcctgtc aatacgatca gcaaatccgc atcgatgatt
      361 tcggctaatt tttctgaagc aaaatcttta tcgattacgg cttctcgtcc ttctaatcca
      421 gtagctgttt ctacaacagg aatcccaccg ccaccaacag agactgtgat aactccttga
      481 tcgaccagcg tttcgatgac acgtgcttct ttaatcgaga tgggtttagg ggaagcgact
      541 acttttctcc atccacgtcc agcatcttct ttgaatgtca cagtggagtc agcattcatt
      601 tgttctttgg cttcttcttc cgtgtagaat ggaccgactg gtttacttgg atttttgaat
      661 gaaggatcat tttcatccac aataacttga gtgactaaag aaaccacatc tttatcgatc
      721 cctttttcct tcagtacttc gcccatggcg ttttgtaacc agtaaccgat agatccttct
      781 gtcattgcaa cacatgtatc taaaggcatt gccggtgttt tctcagaatc agcagcttgc
      841 tgctgaatca ataggttacc gacttgcgga ccatttccgt gggagatgat caattcatct
      901 ccttgttcga taaatttcac taaatacttt gctgtttcca ttaacgcttc ttgttgggct
      961 tttgcacttg catccgtaga caagatggca ttgcccccta aagcgacaac tacttttcgt
     1021 ttggccattt cattcgtcct ttcttcagtt ctaccgaatt ttctagataa caaaacgagc
     1081 cagcgttttg tgattttccc tcaatgctga ctcgtttttt cgtgagatga atgtggttat
     1141 gcttaaacgc gagggataaa caagttacct aatgttgctg ccatgatcgc tttgattgag
     1201 tgcatacgat tttctgcttg gtcaaattga cgagcatatt tgctgcggaa gacttcatct
     1261 gttacttcca tttcagtgat gccaaagcgt tctttcattt gttcaccgta aacagtgttt
     1321 gtatcatgga aagctggcaa gcagtgcaag aagatcaaac gatctgtgtt gtgtgttttt
     1381 tctaccattt ccatattgat ttggtaaggt ttcaacaatt tgatacgttc ttcgaattta
     1441 tcttcttcac ccattgatac ccatacatca gaataaagga cgtctgctcc gtctacacct
     1501 ttatcaacat cgtcggtaat catcaattgt gcaccggatt tttcagcaaa gccttctgcc
     1561 attttgacga tttcttcttc aggttgtaat tcttttggtg caacgatacg catattcgct
     1621 cctaaaattg cacctgtgac taataaagag ttagccatat tgtttcgacc atctccgcag
     1681 taagcaacag tgataccttc tactgttcca aagttttctt ggatagttaa aaagtcagcg
     1741 atcatttgtg ttggatgcca ttcatcagtc aagccattcc aaactggaac accagagaat
     1801 tctgctagtt cctctaccat tttttgactg aatccacgga attcgattcc gtcaaacata
     1861 cgtcctagta ctttagctgt atcttctgtg gattcttttt tacctaattg gatatcattt
     1921 gcacctagat attcaggatg tgcacctaga tcgatcgctg cagtagtaaa tgcagaacga
     1981 gtacgtgtag atgttttttc aaataaaagc gcaatatttt ttccttctag atagtgatgt
     2041 gggataccac gttttttcaa gtctttcaag tgttctgaaa aatcgatcaa atattgtaat
     2101 tcttcttttg taaagtcttt ttctgctaat aagcttcttc cttggaatac tgattctttc
     2161 atattaaaca ttctccttta gattgttttt atttaagatt aaagaggaaa tcccgacggc
     2221 agctgacagt aagactgccg tcaggaaaca aattacttca agtcttcacg gacaagtggt
     2281 tggctcatgc agcgtggacc accacgacct cgtgacaatt cacttgaatt gatttctaac
     2341 actttgatgc catagctacg aagcaattcg ttcgatacat aatttcggtt ataagtgact
     2401 acaacacctg gagcgattgc caatgtgttt gatccatcat tccattgttc tcgaggtgca
     2461 acgatctcat ctccattacc agttgggatc agtacaagat catctaatcc aagagcagct
     2521 ttcatcgttt cgtgtaagtt atctgaatga gtaatcttga tatcatcacc atctggttcg
     2581 attgtaaaga catccatctt accgtcttta ctttgaattg ctggatggat agtgaattta
     2641 tcgtgatcta ccattgtaaa tacggtatcc aaatgcatca ttgcacggtt gttcggaatt
     2701 ttgattgcca acactttttc aaatcctgaa ttttttgcga ataggtggcg tgctaatttt
     2761 tctaaagctt tcgcattagt tcgttgagaa atcccaacag ctactacttt atcgcttaag
     2821 atcaattcgt ctccgccttc gatatgatct ggattttcac gatccaacca tacttcgatt
     2881 cctttatttg caaatcttgg atgatgtttc aaaatatatt ctgtaaacat cgattcacga
     2941 cgacgtgctt caaaagtcat cttattgact gtcatcccat ttcccattga tgcggaaggg
     3001 tcgcgtgtaa agtacaagtt tggcattggg tccatgtaaa atggatagtc atcgtctgct
     3061 gacagatcat atagactgct agaacgtact tcgatatctt ttgtacgaac cccagccatg
     3121 attttatcta ccatttcttg cgtttccatt gatagaagga actcatgaag accctctctt
     3181 acagcattcg atgcaatatg agattcatcc aacattttat tcaagaattg ttctttgaca
     3241 ttgcctgcgt caatcgcttc tgccgctaat ttttccaagt aaagagtctc gacgccttca
     3301 ttttgcaatg tcttcgcaaa gttgtcatgt tcttcttgag caatcggaag atatggaata
     3361 tcatcgaaca acagacgatc cataatatct ggtgtcaaat tttccacttc ttgtccaggc
     3421 cgtttcagta aaactgtctt taatttccct atttcagaga aaacgtgaat aggtttatcc
     3481 atgttgtgtt gcctccttct ttttgattac atgtatagga tatcctcctt ttgtaatcac
     3541 tttcataatt ttgtctcatt caaaatgaga cattcctcac attaatattc gataattaaa
     3601 taattaaacg tttttctatt tttaagcgta atttattcat tttttattct gtatacactt
     3661 tcaaaaaaat atttattcat tgaaaaaatt tttttgaata aattaaaaaa ataaattata
     3721 ttatcgttgt tagcgtttac tatatgtatt attgttgttt tttatacaca aatcattcgc
     3781 ttcaaaacaa attattcaat accattgtat attttttaca taataacaaa ttatatttgt
     3841 aaagtattaa aacttgtttc taatgttggt atgttaaaac tttacaaatt ctttaaaaaa
     3901 agtgacaata aatatagtga acaataagga gaggactttt taatgcgtgt taataaaatc
     3961 gattttcact tttcaaaact cagatatcaa cctgattttg aacatttctc ggatgaagag
     4021 ttccaacaga tcaaggaaca tactgttctt cgttcttata aaaaaggaca gatccttttc
     4081 gacgatggtg atcccagaca acggttgtat atcttgacca aaggactcgt tcgtttagaa
     4141 cgttatgatg aaagtgcaac ttattactac tatgactatg tgaatacaaa taaccttttt
     4201 cctatgtcag gaatgtttgg agaagagacc tacacttata cagctcaagc gatgactgat
     4261 attgaaacat tctaccttcc tgtttcctac tatgaaaaat tagcacgaaa aaatcccgaa
     4321 cagttgatct atatgataca aaaaatttct aaagtagttg aaatacatga attgcgtatc
     4381 caaatcggat tgacctctag cgcctttgac cgggtaaaac aaaatttatt cattttgaaa
     4441 gaagaattgg gcgtaccaac aaaagatggt catatcacca ttccttatcc gatcacctta
     4501 aaagaattag cagtgaatag cggcacgaca cgtgaaactg ctggacaagt aatcaaacaa
     4561 ctacgtgatt ccgggctgtt agattatgac aaaaagcgtt ttactttctg taagacagct
     4621 actactccag ctatgagaga ataacgcgaa caaaaataag cagtgaccct gataaatatc
     4681 agggtcactg cttattttcc tccctaaaac ttctgaaaga tccggcagtt ttagatcact
     4741 ggacaagact caaagatttt ctatgtgtgt ttcagttatg taatattcac tgtttgcaaa
     4801 aaatactgtt agattaacta gatgaagcgt cttgtcctca tccgatctag attattcgat
     4861 attcctcgac aataaacgat tactcagtga gggcaatcag aggaacggat aatgataaat
     4921 aagctgtaaa aaatagcaaa ataacaataa tgattaaaag tatgtaaaaa atagggcttt
     4981 gacaaaaacg tgtcacagcc ctatttcgat taaacggtgt gtacctgtca actcttcggt
     5041 cacaagtcat aatgttcata aacatgagga gctgtttttt gaaattgttc cttgtgaatc
     5101 agagttaaac gacaggctta cgaactcttg attaaacggc gttcaaaagc ttgcatacgc
     5161 ggtaataaga acagccaggt caaaaacatg agaagccgtt tttcctgggc tgttcttatt
     5221 acttgatgca gggcagcttt ttcacaacct ctttattcag ataaaaccaa gcttggatca
     5281 gcattcaact gatagctagc aaaatttctt ttttgcattt ccacatgtgc tgctgctcca
     5341 atcattgcag cattatctcc acaaagtcga agagggggaa tcactagttc tacctcaggg
     5401 agtttagttg ccaaagcatc ctgcaatcct tcacgcaacc cttgattggc cgctacacct
     5461 ccagctataa tcagttgctt gactggataa ttttgacaag ctcgaagtgt tttagtaatc
     5521 aatacatcga tcacacttgc ttgaaagcta gctgctaaat catttttgtc tagatcttct
     5581 ccacgctgtt gtgcattatg caccaaattg ataaatgcac tttttaatcc gctaaaactg
     5641 aaatcataat tatcttcatg gatcatcgct cgcggaaaat ggtaattatc ttttccctga
     5701 tgagctagct gatcgatttc ttttccgctt gggtaagaaa gacctaatac tcttccaact
     5761 ttgtcataag cttctcctgc tgcgtcatct cttgtctccc caatgatttc atatgatcca
     5821 tcttcttgca tatagactaa ttctgtatgt cctccgctaa caagaagtgc catcaatgga
     5881 aactggaatg gtttaaccag acgggctgca tagatatgcc ctgccatatg gtttacagga
     5941 ataagcggca attggtgtgc ccaagcaaaa gccttagctg cagaaatacc aatcagcaac
     6001 gagccgacaa gtcctggtcc ataagtgaca gcgactgccg ataaatcttc tgccgacaca
     6061 ccagcttcta ccagtgcatc ttccaagcat aaggtgattt gttctacgtg atggcggcta
     6121 gctacttcag gtactacgcc accaaaacgt ttatgactgt ttatttgaga agcaacgatg
     6181 ttagataaga tctctgttcc atttctaacg accgctacac tcgtttcatc acaacttgat
     6241 tcaatcgcca gaatcaattc ttcattcatt tcatcgtctc cgtttttaac tttctgctca
     6301 taatgatcgc atcttccgtc ggattgcgat aatatgattt ccgtttacct aatatacgaa
     6361 acttttctga ttcataaagt tttcttgctg cttcattaga tagacgtact tctaaaaaaa
     6421 catgcagcga atcttttatt tgttccgtaa tcagtaattg taacaaatgc cgtgcatgcc
     6481 cttttccttg ttctgaaact gcaacagcaa tatttgtgat ctcgacttca tctattactt
     6541 tcgagtatcc aataaagcca cagatctggt tatcttcagc taaaagcaga taatcagagt
     6601 gaggctgttg gatgtctgcc aaaaactgca ttttcgtcca aggtgaacca tgtggataag
     6661 cattttcgct aatcatccat acgcattctg ccaagtacgc ttcatcaaaa tctttttttc
     6721 tgcaaatcaa ctaatctcac tcattttcta aaagttttat catatccaac gcatcttctt
     6781 ttgtttcagt gtaatatctt tttttgatcg ttgttgcttg aaaccccaat ttccgataaa
     6841 gtctttgtgc atcttgatta ctcatacgca cttctaatga catcgtctca cagcgattca
     6901 ttatagcaaa gttctcgatt tcgtcaataa gcagcgaacc gattcgttta cgctgatatg
     6961 ccggtcgaac ggcaatattc gtgatatggc aatctaaacc gaacgctctt gaaccgataa
     7021 aaccaatcat tcttccatta tcaaagatac ctagatatag atgaggaagc ggtgacttca
     7081 attctgatat aaaggcactt tttgtccatg gcaattcgcc attatagact tctcgttcga
     7141 catccagcag ctctttgata tcttctgtag tcaattctct tagtacgtaa cgacgatcga
     7201 tttgttcgac tgttttttct gtataaatca ttttatcttg aaaaaagctt ctggcatacg
     7261 ctctaaattt tttcaacata actttcgtct ccaggtgtgt gcgtctccaa ccatttttct
     7321 tctgcttcta ctcgttttaa atagcgagga agaaaagctt gtttctctgc aactggttca
     7381 actaaagcac ctaattgagc cacagttaca ccacttggaa tatcccatgc tggaactgta
     7441 ttaatcatcg cactaggcaa tatttccttt atttcagaga agaatttgtg acaatcactc
     7501 ccgacgaaat aaatagcttc attcagcttt tgtagttgtg tgaacaaatc agaagcagaa
     7561 atatgtacat cttcaagtac agtttctaat ctattttctt tccagcggta tgccccagcg
     7621 tatacatttt ttcttcgagc atcaaacatg ggcacaataa tattatccac accgatgcaa
     7681 ttagccgcga tggttttcag actagatact cctactagct ctttatctaa tgtataagca
     7741 atcgtttttg ctgtcgttac acctatacga agccctgtat aagaaccggg accatcagaa
     7801 accgcgattc ggtcaatgtc ttttggactt atttgaagat ctgcaaacaa ttggtcgatt
     7861 gcaggcatca gtgttacact gtggttgcgt ttgatatttg tttgtatttg tccaagaatt
     7921 tgttcgtctt ctaccacacc gatcgccaaa gtttggtttg cagtatctat tcctaatgta
     7981 atcatatatt tgatcctttc tgctatgaca ttctcgcctt ccattgtagc atactttttt
     8041 attctgagga tgaaaatacc aaaggcaaaa ctagtacaat aatacatgat tatctgctgg
     8101 cgggcaaatt ttgccccttc ctgaaacaca aaaaagctgc ggtatcactc cattttccca
     8161 cagcttttcc atcttttatt tcgttgattc tcgaataatc aactctgttt ccacaataat
     8221 ctttcttgaa accggtgctt tggaattact taattgaaga atcgtctcca ctgctagctc
     8281 tcccatccat tcggtataaa cttttacagt agaaagcgag ggcgttacat atttcgctac
     8341 actgacatca ttgaagccca tcacagaaat atcttctggt accactaaac ctttttcttg
     8401 aatcgctttc agtgcgccaa tcgctaatgc atcattagct gcaaaaagcg catcaggaac
     8461 atgcggattc gtttttaaat actgcttcac tgcttgatat cctgactcga cagaaaaatc
     8521 tgcttcgata attggacctt cgtcgtagcc tttttctgcc aaaacttgtt gaaatgccat
     8581 aattctggga tcttttagcc gctgatggtt tttcttcgta tattctgttc cagcaagcat
     8641 agcgatatgt tgcgctttat gggagacaaa gtgttcaatg actttttgaa cacttgactt
     8701 aaagtcgaca actagagagt cgattccttg agaagtgccg tcagaatcta ccaaaagcaa
     8761 ggcattttgg gatcctttca tttctaataa ctgagcttcg tcgaattttc ctagtgcgat
     8821 cgttccatct gccggaagat cactaatgga atcccacgtt tctttcaata aagtaacgtt
     8881 tgcttcttct gccttttttt cgattcctag gcgaatagat aaataataaa gatcttcaag
     8941 ctcttccgta tcgtcgtacc actggatcag gcgaagcgtt tgcttagtat ttgctgcatt
     9001 tttacgatgt ttcgtataat ttaagcgttc tgctgcttca aaaatttttt gctttgtggc
     9061 taagccaacg gaaagatcag gatcatagtt gagaactctt gaaacagtag caggagaaac
     9121 tcctgccaac tgcgcaatgt ctttaattgt tgccatttgt ctctcctcct tttttacgtt
     9181 tataaaatcg cagtaaatcg ttcaaacgct gcctgtcctt tttcatctcg cttgaatact
     9241 ccagcgtctt ccagtacacg tgcaaaaacc tgacctacag atttttgtac gacatcggtg
     9301 accgtatctt tcgtcaaatc aggatgttct ttttttaatt gttctgccca cggacgatga
     9361 tattcagcca tctggttttc ttctcctaat aagaaatgct ctacttctac tagttctggt
     9421 ttcaaacgag gtggtaaaac agcaagcccc attacttcga tcaacccaat gttctccttt
     9481 ttgatatgtt ggacatcttt atgtggatga aaaatcccat caggatgttc ttctgaaaca
     9541 ttgttgtctc gaaggacaag gtccaactca aagtaattgt cccttcttcg tgcaattggc
     9601 gtaatcgtat ggtgtggtgt accatctgct gaaaaagctc tgatagatac tgtttcatcc
     9661 gaatatgctt tccatttttc caatactgag ttagctgctt caataagcaa gtttttctct
     9721 gttgattgca aacggatcac agacatcggc catttcacga ctcctgcgat gacttgcgga
     9781 taatcttcta gtttgataag tttttctatc ggtgcttttg ccataggaaa ttcatgacgt
     9841 cctgcctgat aatgatcatg agaaagaatc gatcctccaa caattggtaa gtcagcattc
     9901 gaaccaacaa agtaatgagg caagacttca gtaatccgaa gcagtctagc aaatgtttcc
     9961 tttgtgattt tcatcgggcg gtgttgttct gataaaatga tcgaatgttc attgtaataa
    10021 gcataagggg aatattggaa tccccagctt tcaccgtcta gattcattcg aataatccgg
    10081 tgattggtgc gggctggata gttcaagcga cctctatatc cttcgttttc catgcaaagc
    10141 atgcaggtag gatagtctac ttttaccgcc tcgcgttctg ctgcgatttg ttttggatct
    10201 ttttctggct tagataaatt gattgtgatt tccagttcac catactccga ctctgccgga
    10261 aatttgatgt tttttgcgat ggctcttgtt ttgatgtagt catttttctt acttaaatta
    10321 aagaaatact cagttgcttc ctctgggctt ttcgaatagt gctgtgcaaa gaatgcattg
    10381 acgactgaag gtggcggtgt gagaaaatcc attaattgcg cttcaaaaat ctcttgttct
    10441 gctggcaatt ctgaaagaac accattttct cttgccttag cgacaagctg atccaataag
    10501 tctacagatt cttccttaac tggtcttact tcaatgcttt ctagagcatc ttctcctacc
    10561 atccctaaaa gacgattctg taaatataag cggtccattt ccatccatcc gccagcttcg
    10621 atcgcaagtg tggcaaaatc acaaatcgtt tgactgattg acatatctca ttcccctatt
    10681 cttcataacc atttggatgg ctgacatgcc aatcccatgc tgttttgata atcgctttga
    10741 tatctgtgta ttcaggtttc cagcccagaa tctctctcgc tttttcactt gaagcgacta
    10801 atcggctagg atctccagct cttcttggtg ctatttctgc tggaatttct tttcctgtca
    10861 cttctctagc tgcttctagc atttccttga ctgagtatcc tttgctgctg cctaaattga
    10921 agaagttgct ttcatttcct tctttcaagt attccaaagc taaaatatgt gcagcaatca
    10981 aatcttctac ttgaacataa tctctgatac atgttccatc tggtgtatca taatcgtctc
    11041 cataaacagc caaggctttt ctttgaccaa gagctacttg taaaatgatt gggacaagat
    11101 gcgtttctgg tgtatgatct tctccgatag atgcatctgc ttttgctccg gctacattga
    11161 agtagcgcaa agcgacatag cgcatgccat atgcttggtc acaccacttc atcatttttt
    11221 ccatcatcaa tttactttca ccatacggat ttttaggatt agctggtgta tcttctgtga
    11281 ttggagactc tttcggctct ccataagttg ctgcagtaga agagaatacg attttattca
    11341 cgttgaactc gtgcatgact tcaagtaaga tttgcatacc gtatacgttg ttgttgaaat
    11401 acatcaatgg tttttcgaca gattctccta ctaaagagct tgcagcaaaa tggattactc
    11461 cttcaatcgg ttccttttca aatacggaac gtagaaattc tttatcccgg atgtctcctt
    11521 cataaaaatg agcatctgga tgtactgctt gtttgtgacc tgtgagcaaa ttatctacca
    11581 cagctacttg ataccccttt tgaactagct ggtctacagc gtgcgaaccg atataaccgg
    11641 ctccgcctag tactaaaatt gtcataaaaa acactccttt gattagtaaa attgtgtttg
    11701 ttgattctat ataatttaaa aaacgaagtt tacttttatg gtgaaaacaa acaaagtaaa
    11761 atttcgtaaa ttcatatggt aaatttataa taaaacattt agtaaacatt ttcaaggatt
    11821 ttttgcaaag gtttacaaac aaacgtaaaa ctagcctttt tttctctttt gttccataat
    11881 agatataaca aataataaat gaggtggatt caatgaaaaa atttgtatct ggaatattag
    11941 taggaagtct ggcaacagcc gctgccgttg ctggtttggt tgcttctgtg aaaaaaacag
    12001 tgatcgatcc aattgacgaa aaagaagcaa tgatcgaaga aaaccgtaaa aaagcaatgc
    12061 gtaaacgcgt ttctcgttaa taattattta aaaatacgca tgaagacttt ctaaaaaaca
    12121 gataagtcat catgcgtatt tttatttgtc agtcaatata agttgtgcta ttttatctgc
    12181 ctgtctcaga ttccatggat ctgtataagg tctagctact gctgcagtta gccaatccac
    12241 accttcaaca ggtattccat agcaataaaa gtcagactgg atttcccctg aagcatcaat
    12301 cacgcgattc gtacctcgct caacatctat agcttctgaa tgataacttc ctgtattatc
    12361 tgaaaatgaa aaagggcgaa caagtttgtt ttccttcaaa ttttttatga caggattact
    12421 tgaacgagaa aagcttgttt gtggcaatcg agcttcaatc aaatagcgac tgctgatttc
    12481 tttatcttgt agagaaataa catagcggtt gtgcttttgc tgaatatcaa atggcggttc
    12541 gatcaaatga aaaatacccg catctatcag tgctgctaat tctttcgtcc gaatgattgg
    12601 cggaccgatc gttaaaaagc tatttagatg agtaaaccat ccccatagta tttctttgta
    12661 ttccttagca gaaaaaacgt gccattcaat agcctgccgg attggatcac gccagtcttt
    12721 taatgcatca aatgttgaag caaatgctcc tgtgcaattg cctttttccg cttcttttat
    12781 ctgcccttca ataaatattc ggctagcttc tgaaaagggc tcattctgat aggcaagagg
    12841 agtttctaaa tacgaccaat cccatctata agggattagt gctggatgct ttccgagaca
    12901 ctcctctgaa gagagggaga gaaaatcatg ctcaaaattt ttctttggaa tcggcaagtg
    12961 atattcttcg atgattttct tgtaataaaa caactcaacg tcttttttca gatagtcaaa
    13021 aaatgtttcg ccagtcaaaa atcccgactg atgccattgc tccaggtttt catttgttag
    13081 taaccgtggc catgccattg ctccgccttg cttttgattt cttcctcgag ggtaataagg
    13141 gagccccctt cttgatccac tgtatacaat cggttccttg cctgatggat gatagaccag
    13201 ttttcccttt tcgttctcga agcgccctcc tcttgatact gtaaacaatc cgacataatc
    13261 aaaaaaactt aagcctagac ctcttaaaaa gacattttct ttaggcggta tcttcgaaag
    13321 atctacatct gcaggattag aaggaagctg atacagtaaa acatttttct ttgcgtagtc
    13381 tacccacact ctttcttctt ctgtctcatc attttcccag tgaccgcttg ctaaaacaag
    13441 ctgatcgata gaatagcttt gctgatctgt ctgtaaaaga taaccatctt ttcttttgct
    13501 tacttttttt actaaagaat aaacaaactg aatagaagct ggaaattctt cttgcaactt
    13561 tgagaaaaac cagcgttgat agagtccgta taaacatcga gtagattgct gatctttttc
    13621 cagacgattg atttcttcta taattagttg cttatttttg gttaccgtct gttcgatata
    13681 atctgtagca ggtcctttac tccattgaaa caagttgggt ccctgtgtta ccaatcctcc
    13741 actggacaat gtttcatctg taaaaagcgt cacttgttga gaaacagaat tcattaataa
    13801 ctccggtggc tgattcaacc gccaaactcg acctccagga ccattgggat cgaaaagaaa
    13861 aagttcaaga gaatgtctgt cctgattatt atggagaatc ctttctgcta cacttaatcc
    13921 tctaggtccg gcaccaatga tccctatttt catttgcatg cctccatttc gataaatttt
    13981 ttcaataaaa cagcatggtt ctgatgttca ttttttgcac cataaacaaa agtaatgact
    14041 ggatgttctt tcataagttg actgagttta aaaatagctt gcttcttttc ttcttcgaaa
    14101 atcaattctt gctggtattt ctttgcaaat gaagcaaatc gttctggtac atggtcaaaa
    14161 gttttgcgtg cttcattact aggtgcaatt tctttcaacc acagatctaa ctgcgctttt
    14221 tcttttgaaa ttcctcgtgg ccagaatcta tccacgagta ttctatagcc atcctctttt
    14281 tcagcatcaa ggtaaacacg ttttaatttg atcatagttg tttccttctt tctacctttt
    14341 cgcttagctt atatatgtag ataatagcac aaaataaaaa aaatgaacgg cacaactatc
    14401 cattgcgccg ttcatgtgat cttggtcaaa atctaatgat tgattcggtt tttaaagctg
    14461 tcatacaatc atctgtttta tactttttta cttttgattt ttccagacca tccgtcatat
    14521 ccacccttaa gtaaataaat ctcttgataa cctgctttac gtaatttatt tgctgtacgg
    14581 atgctcaaac ttttcttttg atcgtaaata tagacaggct ggtcttttcg aatagatcct
    14641 aatgaatctt tcaaaacagt gtaagggatg tttcttgcac ctaaaatatg cccagcatca
    14701 aacacatctt tttcgcgaac atcgattact tgtgcttttc tcattccttc tcgaaattct
    14761 tcttctgtca aagtcgttgc tgaacgtttg gccattactc gtagatagac ttcccaaagg
    14821 atgattgcaa gcacaatcaa tagcaaaatg atattaatta cccataaaac catgtaatgc
    14881 ctccgttttt ttaagcaaat ttcaaggcta atgaggcagc accaatgaca ccagcttcat
    14941 taccaagctc tgctaatttg atttttgttg attctcttac ttgcgggaaa gtaaattctt
    15001 taaaatattt ctctacacgg ctacgtaaaa attctcctgc tgccgatact cctccaccta
    15061 acacgatact tgacggattt aatgtattcc ccaagtttcc gcaagctaaa cctaagtaga
    15121 agcatacgcg atcaacaacc atcaatgcaa acggatcgtc ttcttgagcc atttcaaaga
    15181 tatctttact tgttacttct tctccgttgt ctagcattgc tttcagtttt gaatcccctg
    15241 cgtattcttc tgccaagaaa cgacctaggc gtaccacacc tgtagcgcta gatacagttt
    15301 ctaaacatcc gcgtttaccg caagtacatt cgaacccttc aggatccaca gtgatatgtc
    15361 cgatttctcc tccagctccg ctcacgccgt gaatcaaatt tccgccagca acgatacctc
    15421 cgccaacacc tgttcctaga gtaacgaata caacgtctgg atcgttttct ccagcacctt
    15481 tccatcgttc acctaaagca gcaacattcg cgtcattatc gatagcgaat ttgattcctg
    15541 ttcctgcctc gatcagtttt ttcacaaatt gaacttctgt ccagtttaag ttatacgcac
    15601 caataaccgt tccagcttcg ctgtccacgc ttcctggggt acccatgccg attccgataa
    15661 agtcttcggc tttcatatta tataaattca aacgatgatt gattgattca atgatttcag
    15721 gaacgatatg cttaccatca tccaaaatat tggtatcgat gctccatttt tgctgaatct
    15781 ctccttctgg tgttaaaatt gcaaattttg ctgttgttcc acctaaatca atcccaataa
    15841 tcttcttgtc cattacaaat ttcctttctt tcggctttct tcaattcggt gctctctttt
    15901 taatatgcgc cacgctgtca tgtatgtatc atgatcaatc aaacggctat catacagatt
    15961 acgcaattcg atagtcatta attcaatgtc atagatgcgt gcacccacat agataaagat
    16021 gccaaatttt ttgaacagct gctgtacatc atataagctc tccatcttta agcacttcct
    16081 tcatattata caagtaaacc atattttttt aaacccagta aaatacatat tacaaaaaga
    16141 aatacaaaaa ctagtgtaga aagaatcctt tggtgtatcg aatagcttgt ctgttgtttc
    16201 ggtagaccca aaacattccc taacactaat ccgccaatta gcccaccgac atgtccccaa
    16261 acatctacag aggtatccag aagaccaaaa acaaatgtca acacaataaa taaaagaaaa
    16321 tgtctgacta gctgctggat cgctgggtta tgtttaaaat gaaaccctaa gataaacaac
    16381 gcaccgaaca aaccgaatat cgaagtactt gcaccaccag acagaacatt cgcttcgtta
    16441 aaagcaaagc ttgctgtatt tcccattatc ccgctgaaca tataaatcaa gaaaaaacgc
    16501 caatggccat agattgcctc gatttgctgc cccataaaat acagtatcag tgagttcatt
    16561 acgaaatgca tcagtccaaa atggatgaag attggtgtca ctaaacgcca ccattcattg
    16621 aagtgaacaa gataaggacc atacattccg gcataataag ggatctcaag tcgcggaaat
    16681 aattccatca tgaggaagac cgctgtctgt atccctaaaa aagcataggt ccataacggt
    16741 cgtcttaacc atgcacgcaa ttttatttgc tgttgataat tcatgaaaac ctcccatttc
    16801 attttagtca ataaacaatt gttggatctt ctgatcaaag ctctccggtt gccattgttc
    16861 attcaattgt tcacgaaaaa caaggctaca tgttttttta tgaaaattat ttaaataccg
    16921 gtcgtaataa ccaccgccaa aaccgattcg ataaccggct ctattgtaga taatacctgg
    16981 tacaatgagg agatcgatca tctccggcaa atagagcttc tctgattgtg gctcaagaac
    17041 accaaaactc gaacgtacaa gaacggactg ttcatccatt tcataaaacg ccatctgacg
    17101 tttcggcaaa gttttaggta caactatttt cttttgttct ttttctgctc gttggataac
    17161 cggctgtgta tccagttcaa attcattcga taaagtcgtc cctatcactt ttgctgactt
    17221 ccagtactcg ctggcgaata gctgtttata gattcgctgt tctttttcct ttttcttgcc
    17281 acttttggcc agatttttca gcttttcgat tcctttccgg cgtaatctta ctttcaattg
    17341 gtccaaaaac tcacccttcc ttctctcata aaatggtata ggaaaaaaag aaaaatagca
    17401 atcgaacttt caaataaatg cataaataga ataaaaagaa gacctagaaa tgattggcct
    17461 tcctttttta atgaatttca actgttcagc gcgtgttttt gtctgataaa aagtgcatac
    17521 agaaaatatg gcgcaccaaa aagggcaatc aaaattcctg taggtacttc cccacttagt
    17581 agaatcactc tagcaaccat atctgcacta agcagaaaaa tggaaccgaa caaaccgctc
    17641 agaacaaagg tccagttatt ttctttacgt acgactagct tcgcagcatg aggagctagt
    17701 agtcctacaa aagataaact acctgtcacc gctacactac cgcttgccaa agcaacagct
    17761 aacaacaaaa ggattttttg acttttagcc acgttaaggc ctaatccttg cgcgcgttct
    17821 tgaccaaatg atagcaatac aatcctctgt gcataaagtc ctcctagcgg aattaagata
    17881 accgcccatg gaagcaatgc ccaaacataa ggccagctcg caccccagat tgatcccgct
    17941 aaccatgcat tcacaaatcc ataattttcc ttagataatt ggatcgtgca tagcaatgtt
    18001 aatgcagaaa ggccggcatt aacggcaata ccggacaata agattcgatt catacccaaa
    18061 aagccatttc gatcataggc cgcaagatag acacagcaag cagctaaaac accacctaga
    18121 aaggctacaa ctagcaatag aaacggcagc gaatagtgcg aaaagaaacc taaataaagc
    18181 atcactaaaa atcctgctcc ggcattaatg cccaatatac tagaatctgc caattcattt
    18241 cttgttactc cttgcaagat ataaccagaa acgccaagac aagctcctgc taataaactg
    18301 atcagtaatc gaggaactcg aaattctcta acaatcagcg ccaaagaaga tgattctttc
    18361 cctatgaacg tggcaaaaag ctgatccagg taaataaaag gcgtaccaat cattaaacta
    18421 cctatagaca ggatgacaag tacaaaaagc aagaaataga acgtccaata tatttttttc
    18481 accgttgttc cctccttact tgtatcagta aaaacggaac gccaatcaat gcaatgacta
    18541 atccaaaagg tgtttcaaaa gggggattga tcatcctcgc tgtaaaatcc gccaacataa
    18601 ccaatccacc gccaactaaa aaagagacag gtagaacata acgatagtcc gttccaacca
    18661 ttccgcgaac aactggcgga accaacagcc caataaatga aacaggtccg actaacgaaa
    18721 cggcaatggc tgctaacact gcaactagac agaaaacaat caaccgcgtt cgtttaggat
    18781 gacttccaag agctaatgca tgtgtttcac tcaaatgaat caaagatatt gcttttccta
    18841 atgaaaaaga aaccaaaaca gcaagtatat ataaaggaaa caatactgct aattgtttcc
    18901 atgtgatatt ggcagctccg cctacaaacc aaaaagcaag atcctgctgc agattaaaga
    18961 attgggtaag tgcttggctg atagcagtaa aaaaagaact aatagctacg ccagctaaaa
    19021 tcagctgtaa aggattcatg cccattttcg aaaactgcaa aaaaccaaat acgagcaaag
    19081 ttacagcaaa agaacctgcc aatgacatta gaaacacaga aaaatcagaa gctttaggcc
    19141 aaaaagcaaa actaagggcc attgccaacg aagcacccgc gttgattcct agtaagcctg
    19201 aatctgctaa aggatttctt gtcactcctt gcatcaatgc accgctcaat gcaaaacaac
    19261 tccctacaag aaatgctccc gccacacgag gcaaacgaat atttcgtatg atttggtgac
    19321 tttgttttga tctatcaaaa tcaaacaacg cctgccaaaa atctgctttt cccacagtcg
    19381 ctgcgccatt tgaaagagca acaaaaaaaa taatcaaaag aacaaaacag accaaaagca
    19441 ggagtctatt tttcttcata gtcctcataa ttgatcctcc tgctcttttg gcaacaaatc
    19501 ataggttaga aaaactggtt tatttgttct tggaagcgtg acaatcgttg catcaatctc
    19561 aaatattttt ttcatacact cttttgtgat cacttcttca ggtgtacctt ctgtgatcaa
    19621 cttaccgttt ttcattgcta ataaataatc tgaaaaacgt gaagcatgat taatgtcatg
    19681 aatcgacatc aagatcgttg tttgtttcat ttgattgatt tcagtcaata actgtaggat
    19741 ctctaattgg tgtgccggat ctaaaaatgt tgtcggttca tccaagatca agatatctgt
    19801 ttcctgagca agcgccatag cgatccagac acgctgggtt tgtccaccag acagcgttgc
    19861 gatatcccgc atacgaaatc cagctagacc tgtagcatcc aacgcccact cgattgcttc
    19921 atgatcttgc gtgtccatgc cactgaacag tttttgataa gggtatcgtc cgtaagatac
    19981 tacttcttct actgtcatac ctgtagggtg ttcactagtt tgtgctaata atgcaatttt
    20041 ttttgcaagt tcttttgaac tgtatgtaga gatatcagag ttattgacaa tgatctttcc
    20101 tgatttcaca ggtagtatac gggtaaaact tttcaataaa gtagattttc cacttccatt
    20161 tggcccaatc aaactagtga ttttcccttc aggaatcgta acagacatgt tttcaatgat
    20221 ttttttgttt tcgtagccgg ctgcaatgtc agctgctctt aatctcgtca tttcacccat
    20281 cctttcgctg aaaatcattc tcaattatga cgctgtttca acatttcgtc aagcgctact
    20341 ttcatatcta tagccaaatg aagcggttga cagcgttcga aatatcagga ataataacca
    20401 atgagaaaga ttctcaatta tgttaggagg aaagaaatga aattaaaaac aaaagtattc
    20461 acattatcta gcatattgct gctggctgga gtactgagcg cttgctcccc ctcttcagat
    20521 aaagaaacag ctacaactgc caattcgacg acttcatcca atagtactca tacagtcaca
    20581 gatacacttg gacataaagt agagattcca aacgcgccca aacggatcat cggcagttac
    20641 ttagaagact atctgattgc actaggggaa aaacctatcg cccagtggac tgttggcagt
    20701 ggttccattc aagattatct gcaagatgat ttaaaggatg tcccaacgat ttcttatgac
    20761 cttccttatg agaaagtgtt aagctttgag cctgatttgc tgttgatttc ttcttccgct
    20821 actgtcgaag gcgggaaata cgaacaatat agcaaaatcg cgccaactta tgttgtaaaa
    20881 aacggaacag atgtcacatg ggaagaacaa ctaaaagatg tcggcaaagc tttggcaaaa
    20941 gaaaaagagg cagaaaagat catttccgat tatcaaaaat ccatcaagaa aactcgagaa
    21001 gaactagcag ataaaatcga gaacaagaca gctgcagtgt tgtgggtgac caacaactca
    21061 gcctttatgg tcagcaaaaa tcggtcaagt ggaagaatcg tatacgacga tctggaattt
    21121 ggtgttcctg atctagtgga agaggtctcc aaaaaagcca cttctgactg gtctgctgtt
    21181 tcctctgaaa agctagctga attagatgct gactacatca tccttgtgaa cagtgacaaa
    21241 gatgctgcca tgttcaatga accaagctgg aagaatctta aagcagtgac agacaatcat
    21301 gtactgcaat tcggacctga atctagttgg ctatataacg gacctattgc cagtcaggaa
    21361 atggtcaatg atatcaaaga aaaactaaat tgattttaac taaaaaaagc atcttcacga
    21421 ttagtcgtga tatgcttttt ttcttattaa caaactagac gcatagattt tattcttctt
    21481 ttgaagcaac cctatttttt actctttccc atttttgaaa acgatgggca tatagatttt
    21541 cttgatccgt tatcccctca tactcctcta taagggcgaa gtctgaaaaa tcaatattcc
    21601 caatatacgt atcgccttca aacgtgctat cgatcaatgt tcgccagatc cgaccagtgt
    21661 aaggaagaag ttcttgaaaa atccgactac cacccgaaac atagatatct tctgagatcg
    21721 tttgactata cgacaaaagt tcatcgatcg aatgcattac ttccgcattt tctttcgtgc
    21781 gaaaatttgg ctgcgttgtc aacacgatga tatggcgata aggaagtgaa agatccccca
    21841 ttccttcata ggtctttctt cccatcacta aaattcgatc cattgtatgt tcgcgaaaga
    21901 aacgcatatc atttggcaat cgccatggta acaaaccatt tttgccgatc agaccatttt
    21961 tatcttgtgc ccacatggaa ataaacatat tatccgctcc ttatgatttt agatgttttg
    22021 agataaaaaa agtctcaatt ctttgaccag caaggaattg agaactttaa aaacattatt
    22081 ttgtttcacg gtgcaaagta actttgcgtt cgcgtgggca atatttttgt ttttccaaac
    22141 gatcaggatt gttacgtttg tttttgcttg ttagatagtt acgttcttta caagaagtac
    22201 actctaaagt gatgtttacg cgcatgtttt tccctcccat ttttacaaga atcctctaag
    22261 atgactctca gacttgatta tcttaccatg attttttcta gattgctagt gtttttcacg
    22321 attttgttaa gtaaaactac ttgacgataa atacaacggt tttacttctc aaacaaaatc
    22381 tttttctttt tgtataaata cccttacact tgtttatata gattatgttt tttaataaag
    22441 ggggatacta atatgccatg gaacatgaag gactttcctg catcaatgaa aaacttagat
    22501 aaattgacaa gaaaaaaagc aatcgacatc gcaaatgcat tattagatga agggtaccct
    22561 gataaccgtg cgatcccaat tgccattgat caagcaaaaa aatggtatga agatgctagt
    22621 gaatcagaaa aacgaacttt cgaaaaagaa aaaaatccaa gcaagacgga tgaacacgat
    22681 acgaatcctc gtgctggaaa actgcttgat tcagatgtga tcgtagaata tgaggaagaa
    22741 caatggatcg tgaaatctaa aggggcaaaa aaggcaagca accattttga tacaaaaaaa
    22801 gaagcaatcg aaaaaggaaa gcaagtagca caaaacaaag aatcaacttt gttcatttat
    22861 aaaaaagatg ggacaaaaga aaaagaaatc gattattgaa catatgtaaa ggggttgtga
    22921 cgaaaatcgt gtcacaaccc ccttatgttc gaaacaatgg tgttcctctg ccaactccga
    22981 accataagtc ataatatcta taaaacggga agagctgttt tttgaaattg tttcttatca
    23041 ctcagtgtta aacggtagga gaaaacctct tttttattga tatttgattt tcatcaaaca
    23101 gtcacatagt cgattgcttc tgcttgcgga atcgtttcat ctacaaagta gactttatac
    23161 catgtcaaga aactgaagat tgtccagatt tttctttgct cttctttacg tccttcgtga
    23221 tggtcatcta gcaacttcat gattttttct tgatcaaaaa attcttttgc aaaatctgct
    23281 tcgaacaatg ctttgacttg ttcgtagccg tgttcttctt tcaaccaagc tttgattggc
    23341 acagggaatc ctaatttcac acgattcgac catttttccg gaagatgttt gttcgcagct
    23401 tgtctgaaaa tatcttttgt gttgttttga ttcaataaaa acttacttgg tatttgttga
    23461 gccaatttca tgacttcgat atccaataaa ggtactcgga cttccaaaga acttgccata
    23521 gaaagtttat ctgcctttaa caagatatct tttggcatcc attgatgaag atcgacatat
    23581 tgcatcttat tgacttcatc tttgattcct tctgttttct cgtaatgaac agtcatgatt
    23641 tcatccacag atggtgctgt ttgatatttt ggtgttaaca cttctgatgc ttctgattct
    23701 tcgaacactc gagcatgacc gataaaatat tcttttgcag gagcaagtga ttcatataaa
    23761 tggatccgtc catggaaatt tttcattttt ccgattttac gtcctaaatt atagcgtgtt
    23821 ccttttggta attttttcaa tccttgagca atcacacgga tgaattttga attcgtatgg
    23881 aatccatacg tttggtatcc cgcaaacagt tcatccgccc cttctccaga ttggactacc
    23941 cgcacacttt gtgaagcaag atttgctaaa aagtacaaag gtacgcaaga aggatttgaa
    24001 tcaggttcat ctaagtgata ctggatcaaa gggaatgctt tgaacgacat gtctccgtcg
    24061 atcactgctg ctgtattatc taagtccaat agttcggtta gttttctggc ttcaatcgtt
    24121 tcattatagg ttttatcatc aaacccgatt gagaaagaat gatctggttt caatacagag
    24181 gttacataac tggaatcaac cccgctggat aagaaagaac caacttctac atcactgacc
    24241 gtatgtgctt caatagaagc ttgaacggtt tcgtcgattt tttcgatcca ttcttgtcgg
    24301 gaatgcgttt cttttgtttc aaaatctgca tcccaatatt gctgaatgtc tatttttcca
    24361 tctttatacg tataataatg gccttcaggc aaacgataga catctttgaa gaatgtttcg
    24421 ccgtttaatg gagaatattg gaaagtcata taaggtttca acgcttcttt gttcaattct
    24481 ttgttaaaat caggatgagg cagaaaactt ttgatttctg aaccaaacat aaatgttccg
    24541 ttcatttctg cataataata tggtttgatc ccaaagtggt ctcttgcacc gaataactca
    24601 ttcttttcat tatcccaaat agcaaaagca aacattccgc ggatcttttg caataattct
    24661 gttccccatt cttcgtaacc atgcaaaagg acttctgtat ctgcatgtgt ttgaaaaacg
    24721 tggccagctg caatcaattc ttctctcaaa ggctggtaat tatagatttc gccattaaaa
    24781 ataatgatct ttgtccgatc ttcattgtaa ataggctgag taccgccctc taagtcaata
    24841 atacttaatc ttctgaatcc taaagcaaca tgtttatcga tatattctcc tgaactatta
    24901 ggtccacggt gaacgattcg atccatcatt gtattaataa ttgttttttt gttgtccttg
    24961 tcgttaacaa aacctacaat accgcacatt taactttcac atcctaatat aaaattactg
    25021 tttatttcat tcatatgcat cttatcatag aataaatagc ggacgaatat tttctctctt
    25081 acaatttcgt cacgtgaaaa caaaagatga aagtttctgt ttttacagga aataaagtcc
    25141 caatatctaa tttaccatgt tttctttttt gaggctacct tattctcttc gtgttaaaaa
    25201 aatattagtg gatgctattt ccaaaaaaac cagcaaaaaa agacacgacc taaagatcgt
    25261 gtctaattat gactgtatca gaaaatatga taccaaacgg atctattcat taattaattg
    25321 acatagttta tctgttgctc ttttatgact ggataactga ccaattcatg acgatccaag
    25381 tcttctttat tcatatttac agcagtaatt tgactgtctt catacgtacg ataataataa
    25441 atccctttat caacgttaca gcaagaagaa taaatcgtat attcgtattt tctttctcca
    25501 gtatcgcata ctcctttttg ttgctcgact gagcctagta tatgaaaaaa ttgactgata
    25561 ctttcagatt ctgaatcacc tgatgcagca ttcattttag taaatgtggc ttttacaaat
    25621 cgagaaacag aagagagatc tccaggtaag cccaatcctc ccatcccacg actataaaca
    25681 ttcaagctga tctggtttga aaaatgattt tctggtgttc catttgatag cgagcgataa
    25741 ttgttcagat taaataattg ataatcaaat ggcggattat ttgtcaacac accgacagga
    25801 ttatcatata aatgaagtcc atctttcata ctttcaatta ctatcgattt ttctttatca
    25861 gctaataacc agtgtaaagg tgacaagggt agtttttcac taaaatcgat attgactaga
    25921 ttgatagtag ccaataattc tttagcttcg tctatggttg agcattgccc tagtatccat
    25981 ggaataaact caaatggtgc aacgttatct tttccttctt gtaattcttt ataatcagca
    26041 ttgccaggaa aattcagtcc tgccatactc aacccttttt catttgtagc ctcataatag
    26101 agtggatagt tggatacccc agctgctatt cctatcattg cataatgttt atctaaattt
    26161 tttacctttc taaaatcgaa acgataattt cttggagtaa tagtgaccac ttcattataa
    26221 gacatctcat aatcaaaatt ccttccaaaa taatggtctt tcgttgcata agtgattgcg
    26281 gtacacatcg tttcccgtcc taaaacaaat cgtttttaca cttttatctt acatctagta
    26341 ttttttttat caaaaaaagg ccaaagaaga ttgatttact agcatttata aaaaatagta
    26401 ctcaggggga atcaaaaaat attgtaggtt aaaagtacaa caataagggg ctgtgacaaa
    26461 agtcttgtca cagcccctta ttccgaacaa acggtgttca aaagcttgca tctgcggtaa
    26521 taagcccaat caaacgaaaa aataggaaaa gctatttttg tttggccgtt cttattactt
    26581 gatgcaggac agcttcttca caacctctaa tcgttgatat aaggaaggta caggatttat
    26641 atatgactgg taatagaaga aaattactag catagtttag cgatttaccc taatttttgc
    26701 ttctagttat aaaatattag cactaactaa atttcaaaac gtagtcaaaa acgtatttaa
    26761 aattgtaatc gggtaagtgt tcgacaacta taattaaact agatttatct atgtactgcc
    26821 cctcaacgag gggctatttt ttatcgttcc cgaaccgtca atatatattc aggaaaatct
    26881 agttcaaggt ttacaaaagg aacatttgtt cgtatactct ttttgaggtg aacattatgt
    26941 taatggaagg aaaaacacaa ttatggttta aatttgatcc ttcgaataga tttgtcaaag
    27001 atttttataa agtatgggat tcagaagttt tctttttagc aattgaagat agcttattaa
    27061 tcaatctcta ctattccaat aaaaactact ttaaaatccc tgctgcaaaa acgagaatga
    27121 agaaagatgt gtattttttg tttgatatcg tgactgacgt gccggacgca cgtagcgatc
    27181 atcggcgtta tgactatata aagtatactt tcgttgatcc agaaagatac aaagattaaa
    27241 gtaggctacc taaaaaggta gcccggaacg gattttatca ccatacttat gaaaggagat
    27301 attttttaag ttagtattaa gattgtgtaa tatgatgata tctatatttt atagtatcag
    27361 tgctataaaa acaaaaataa gtcactaatt aactatcact ccaattataa gcctttttcc
    27421 cattattttt tacagttata tggtatgctt tttaatggct tcaaatataa aagagtttaa
    27481 agcgtaacac acttatgggg gagtggtttt tggggaacgc tttaaactct tctttattat
    27541 tatctcacaa tataacccaa atgtctttc
//
LOCUS       DAFEIE010000033        27335 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFEIE010000033
VERSION     DAFEIE010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.034"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(88..456)
                     /gene="rplL"
                     /locus_tag="LP345_001601"
     CDS             complement(88..456)
                     /gene="rplL"
                     /locus_tag="LP345_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBL1760386.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(509..1012)
                     /locus_tag="LP345_001602"
     CDS             complement(509..1012)
                     /locus_tag="LP345_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBL1760387.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(1216..1343)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(1422..2111)
                     /gene="rplA"
                     /locus_tag="LP345_001603"
     CDS             complement(1422..2111)
                     /gene="rplA"
                     /locus_tag="LP345_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBL1760388.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(2215..2637)
                     /gene="rplK"
                     /locus_tag="LP345_001604"
     CDS             complement(2215..2637)
                     /gene="rplK"
                     /locus_tag="LP345_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBL1760389.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            2980..3648
                     /gene="sdaAB"
                     /locus_tag="LP345_001605"
     CDS             2980..3648
                     /gene="sdaAB"
                     /locus_tag="LP345_001605"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBL1760390.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            3661..4533
                     /gene="sdaAA"
                     /locus_tag="LP345_001606"
     CDS             3661..4533
                     /gene="sdaAA"
                     /locus_tag="LP345_001606"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBL1760391.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(4624..5643)
                     /locus_tag="LP345_001607"
     CDS             complement(4624..5643)
                     /locus_tag="LP345_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL1760392.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(5816..6721)
                     /locus_tag="LP345_001608"
     CDS             complement(5816..6721)
                     /locus_tag="LP345_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1760393.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(6780..7325)
                     /gene="nusG"
                     /locus_tag="LP345_001609"
     CDS             complement(6780..7325)
                     /gene="nusG"
                     /locus_tag="LP345_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBL1760394.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(7426..7596)
                     /gene="secE"
                     /locus_tag="LP345_001610"
     CDS             complement(7426..7596)
                     /gene="secE"
                     /locus_tag="LP345_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBL1760395.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(7620..7772)
                     /gene="rpmG"
                     /locus_tag="LP345_001611"
     CDS             complement(7620..7772)
                     /gene="rpmG"
                     /locus_tag="LP345_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL1760396.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            7934..8578
                     /locus_tag="LP345_001612"
     CDS             7934..8578
                     /locus_tag="LP345_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1760397.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(8634..9137)
                     /locus_tag="LP345_001613"
     CDS             complement(8634..9137)
                     /locus_tag="LP345_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL1760398.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(9150..9196)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            9734..10699
                     /locus_tag="LP345_001614"
     CDS             9734..10699
                     /locus_tag="LP345_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL1760399.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(10798..11970)
                     /locus_tag="LP345_001615"
     CDS             complement(10798..11970)
                     /locus_tag="LP345_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760400.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(11957..13102)
                     /locus_tag="LP345_001616"
     CDS             complement(11957..13102)
                     /locus_tag="LP345_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760401.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(13116..14048)
                     /locus_tag="LP345_001617"
     CDS             complement(13116..14048)
                     /locus_tag="LP345_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760402.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            14165..15244
                     /locus_tag="LP345_001618"
     CDS             14165..15244
                     /locus_tag="LP345_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL1760403.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            15241..15870
                     /locus_tag="LP345_001619"
     CDS             15241..15870
                     /locus_tag="LP345_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1760404.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(15980..16207)
                     /locus_tag="LP345_001620"
     CDS             complement(15980..16207)
                     /locus_tag="LP345_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1760405.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(16310..18898)
                     /locus_tag="LP345_001621"
     CDS             complement(16310..18898)
                     /locus_tag="LP345_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBL1760406.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(18918..19577)
                     /locus_tag="LP345_001622"
     CDS             complement(18918..19577)
                     /locus_tag="LP345_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1760407.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(19626..20129)
                     /gene="trmL"
                     /locus_tag="LP345_001623"
     CDS             complement(19626..20129)
                     /gene="trmL"
                     /locus_tag="LP345_001623"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBL1760408.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(20350..21216)
                     /locus_tag="LP345_001624"
     CDS             complement(20350..21216)
                     /locus_tag="LP345_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1760409.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            21325..21966
                     /locus_tag="LP345_001625"
     CDS             21325..21966
                     /locus_tag="LP345_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBL1760410.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(22028..23389)
                     /gene="mgtE"
                     /locus_tag="LP345_001626"
     CDS             complement(22028..23389)
                     /gene="mgtE"
                     /locus_tag="LP345_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBL1760411.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(23407..24306)
                     /locus_tag="LP345_001627"
     CDS             complement(23407..24306)
                     /locus_tag="LP345_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL1760412.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(24308..25105)
                     /locus_tag="LP345_001628"
     CDS             complement(24308..25105)
                     /locus_tag="LP345_001628"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBL1760413.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(25083..25787)
                     /locus_tag="LP345_001629"
     CDS             complement(25083..25787)
                     /locus_tag="LP345_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBL1760414.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            25918..26493
                     /locus_tag="LP345_001630"
     CDS             25918..26493
                     /locus_tag="LP345_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBL1760415.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            26611..27288
                     /locus_tag="LP345_001631"
     CDS             26611..27288
                     /locus_tag="LP345_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL1760416.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         7976 a         5761 c         4921 g         8677 t
ORIGIN      
        1 tctatattca ttaaataata gtttaacata aaaacaaaaa agcaccgaaa tccaacatag
       61 gatctcagtg cttttaaata gtaaaaatta tttaacagtt acagatgcgc caacttcttc
      121 aagtttagct ttcaattctt cagcttcttc tttagatacg ccttctttaa ctggtgcagg
      181 agcgccatca actacagctt tagcttcttt caagcctaaa ccagttgctt cacgaactgc
      241 tttgataact ttaacttttt ggtctccagc tgcagttaat tctacagtga attctgtttg
      301 ttcttcagca gcagcagcgc caccagcagc agctacagct acaggagcag cagcagatac
      361 gccaaattct tcttcaatag ctttaactag gtcgttaagt tctaggatag ttgcttcttt
      421 taactcagca acgatgtttt caatgttcaa tgccattata atttcctccg tttaattgtt
      481 cttttttatt taatgcttta tgcggcaatt aagctgcatc tccatcttct ttgtctgcca
      541 ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg tagtacagat agcaacatag
      601 atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt gatttcttcc aatgaagaga
      661 ctttaccttc gatgataccg cctttgattt ctaatgcttt tgcttcttta gcaaattcgt
      721 ccatgatttt cgctggtgcg actacatctt cgttactgaa tgcaacagct gtaggtccag
      781 tgaatacttc gtccatgcct tcaaggccag cttttttagc tgcacgtgaa agaatagaat
      841 ttttgataac tttcatttct acgttagcat cacgaagttg tttacgtaaa cgtgttactt
      901 catcaactgt taatccgcgg tagtcaacga ctactactga tgcagctgct gtaaattttt
      961 cgcttacttc atcaacgatt gctgcttttt ttgcgataat tgcttcactc atttttgagt
     1021 ttcacctcct gaattttgat ggaagagttt tttgcactga aaaggcaagt cacttttata
     1081 gttactttgc tcaaccagta ttattcatca cctattcact tcgttcatag tgattctact
     1141 cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc agtattgttc atcatctctt
     1201 cacttcgttc atagtgattc acaataaaaa actctatgcc accgcagaca tagagggact
     1261 attgaatata ttcaataaac gtcctcggta ggaaattaag gcttgatgcc acctactgtc
     1321 ttcggtacaa gttaattatt aacctcaact agcttagcat gctaaactag ttgagtcaag
     1381 aattattttt cagttggatc aatcaacatt ctaatattta attagaaaga agcttggtca
     1441 acatggatac caggtccaaa tgttgttgtg atcgttacat ttttcatgta ttgaccttta
     1501 gctgctgatg gtttagcttt tagcaataca tcatggattg ctgcaaagtt ttcaactaat
     1561 ttttcatcgt caaatgaaac ttttccgatt ggtacatgga tatttccagc tttgtccaca
     1621 cggtaagtta ctttaccagc tttcacttcg tttactgctt ttgttacgtc cattgtaact
     1681 gtaccagttt tagggtttgg cattaagcct tttggtccta atactcgtcc tagacgacct
     1741 acagtagcca tcatatcagg tgttgcaaca actacatcaa agtcaaacca tccgttttgg
     1801 attttttgaa ccatgtcgtc gtcacctacg aaatctgcac cagctgcttc agcttctttt
     1861 gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt taccagttcc gtttggtaat
     1921 acaacagcac cacggatttg ttggtctgct tttttagggt ctacgttcaa acggtatgca
     1981 acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt ttgctaaagc tactgcttcg
     2041 gcaacaggat aaactttact tgaatcaact ttttttaatg catcttgcat ttttttgctc
     2101 tttttagcca ttttggttcc tccttgattg tggttataac ggttgtacct cccacgtgtt
     2161 ctatatcttt caatatagag ccaactgaga agctgctgtc ttagggtgta tagattattc
     2221 tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg cgcattgctg cttcaacgtt
     2281 agctgcgttt aggtcttcca tttttaattc agcgatttct cttacttgat cgctagaaac
     2341 tttcgcaact ttatttttgt ttggttcgcc tgaacctttt tcgattttag ctgctttttt
     2401 caatagaaca gcagctggcg gtgtttttgt aacgaatgtg aatgaacggt cttcgtatac
     2461 agaaataaca accggaatga tcaaacctgc ttgatcagct gtacgagcgt tgaattcttt
     2521 tgtgaatccc atgatattga tacccgcttg acctagtgca ggacctactg gtggagctgg
     2581 agttgcttta cctgcaggaa tttgcaattt aacgattttt tctactttct ttgccacgag
     2641 acatacctcc ttaagtccgt gatgtggtta attggagatg catatttctc ctcccacgtt
     2701 ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa caatgcacac tggtacagta
     2761 tagcaaattt atttgttttt tcaagatttt tttctgctat ttttacattt tgcttgaata
     2821 aacgctaaat ttattctaaa aaaacaacaa tttttcgttc tcatttcttc ttttatgtta
     2881 cacttgcgct agcatggttc aacagatgaa agcaaacaat aacacggttt tttagaccct
     2941 tgtacaaaga ttcctacata acaaaatgag gtggagaaaa tgaaagattt aaggtataga
     3001 agtgtctttg atattattgg acctgtgatg attggtccaa gtagctctca cactgccgga
     3061 gctgctagaa tcgggaaaat catacgtagt atatttggcg aacagcctga ttctgtagat
     3121 atttatctat atgaatcatt tgcaaaaacc tatcgggggc acggaacaga tattgcatta
     3181 gttggcggcc tgttagggat ggaacccgat gatgaacgtt tagctgattc tttgaaattg
     3241 gcatatgaag ccggtatgga agtcttgttt gttcctaaga gtgaaaaagc cgaacatcca
     3301 aactctgtaa agatgcttct aaaaaaagga acacgaaagc tttcagtcac tggcatttcg
     3361 atcggcggtg gcaatatcca gatttctgaa ttgaatggat tcaaaatttc tttaagcatg
     3421 ggtactccta ccttgatcgt tgtccaccaa gatgttccag gtatgattgc taaagtgact
     3481 agtatacttt ctgagaccaa tacgaatatc ggcactatga cagtgacacg ggaatcaaaa
     3541 ggtgaaaatg ccattatgat aattgaagta gatgatcctc aagtagaaga aacggtaaaa
     3601 agactcaaac agctgccaaa tatcgacagc gtaaattatt tcgattaagg agctaaaaaa
     3661 atgtttttat cgattgaaga attagtagat caagcaaaag cttatccaag tgtagcagaa
     3721 ttgatgattg cagttgaaat ggaaatgagt ggccgttccc gtagtcacat catcgagatc
     3781 atggaaaaaa acctctcagt aatggaacaa tcaatcaacg agggaaaaga aggtgttacc
     3841 tccgtcacag gaattaccgg tggtgatgca aaaaaattag atgattattt aaatgaggca
     3901 gactttttaa gtggagaaac aatcttaaaa gctgtacgca atgctgtagc tgttaatgaa
     3961 gtcaatgcaa aaatggggtt gatttgtgct acaccgactg ccggaagcgc gggtgttgtt
     4021 cctggtgtgc tgatggctgt ccgagatcgg cttgatttga cacatgaaca gcaattggaa
     4081 ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa acaacgcttc tatcagtggt
     4141 gcagaagggg gatgtcaagc agaagttggt tctgcaagtg caatggcagc agcagctttg
     4201 gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag cagtagccat tacattgaaa
     4261 aatatgatgg gactgatttg cgatcccgtt gcaggcttag ttgaagtccc gtgtgtcaaa
     4321 cgtaatgctt taggctcttc tcaagctttt atctctgctg atatggcatt agcgggtatc
     4381 gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt accaagtcgg acgtcaaatg
     4441 ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg ttacgccaac tgctaaacga
     4501 cttgcggaag agattttaaa taagagggcg tgataaagct ccttaatttc gagtattaag
     4561 agattagtta tcttcataac aaaaaacgaa gagaggacta attgcccttc tcttcgtttt
     4621 ttattaatcc atcaatttcg tattttttac ttcatcgatc gtttttgttc ctgcaagttg
     4681 catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca gatgttactc cttctgcccc
     4741 acctagattc aacccataaa tcactggtcg gccaatcgca actaagtcag caccacttgc
     4801 cagagctttg aagacatgct ctcctcgacg gacaccagag tcgaaaatca ctggtacacg
     4861 tttgttgact acttcggcaa tttttggcaa tacttcaaag gacgcaggac ctccatctaa
     4921 ttgacgtcca ccatgattgg atacccagat accatctgcc cctgcagaga tagcgattac
     4981 tgcatcttct ggcgattgta ttccttttac gataactgga agatgggtga tttctttgat
     5041 tgttttgatg tcatctggtg tcaagccttg ttttgcagct gcataaattt ctgcgattcc
     5101 ttttccttcg ccattaccac ttgcactttg ttcgctatac gcagctaagt taggcattgg
     5161 taatggaaat tggaattgat tgatgacgtc ttcttcacgg taaccaccga gcgttgaatc
     5221 tgccgttaaa atgatagctt tagcccctgc ttctactgct ttgttcaaaa tgaactcatt
     5281 gaatctgtcg tctttactca tatataattg gaaaaactgc ggtgcgcctg gcgctgcatc
     5341 ggctgcgtct ttgattgtcg tatttgcata agtgctgatg gaaaagattg atccagcagc
     5401 agctactcct ttagctgtat cagcttcccc tttttcatgt gccaatcctt gggccgctga
     5461 tggcgcttgg ataatcggtg tatctaattc aattccgaaa acagatgtat gcaaatcggc
     5521 tgagtcgatt ccgcgtaata tccgtggcat gattttcttt gtattaaaag aagtcgtatt
     5581 ttctttcatc gtccactcat cttcagaacc accgcgaata tagccaaaag ctcctgcttc
     5641 catgcgctct tttacacgac cttctagtta ggcaatgttt acaatatcga ttggatgttc
     5701 ttcattactt gtatgataag tcatagtaga tccttctttc atcttcttga ttacatataa
     5761 atcatactaa acttacaaaa agtaagcaaa catttactct cagatacttt tatcgctatt
     5821 ctttccaaat aaatcgactt acaagctgat ctacttcttg gttttcatga agcatactat
     5881 gagaggcatt ttcacctgtc actacttttt cctctatttc atttccgcgt tgcttcaaca
     5941 acgcatagac cgctaatgca ctgtttaacg gtactgttcc atcactcaag tctgtttcat
     6001 ctagttgacc agcaatcaag aaaaatcgag tggttatagg aatattaccg atcatttgct
     6061 ggtaatcttg atagcggtta gaaacgacag caggcccctt tgctaactca tctgtcagag
     6121 actgcgcact atcatcgaca aaatcattaa aaggcgcgcc aattgctgtt aatgtctgaa
     6181 cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata gcgtagtgca ctaactcctc
     6241 ccatggaatg ccccactatg ttgactttat ctatgccgta gttttctttc agatacaaaa
     6301 gacaagtttt gatccattct gcttgattcc actcgttatt tttattatct tcaaacaata
     6361 cttggaccat cggattgtct gcttttccag acaaatctcc tgttgcttgt atttgtccat
     6421 ctgttcctac tgttaaaacc aattctttta ctgcttgctg atttttttcc aaacgccgca
     6481 acatcccttt aaaggaattt tctgtcccgc tgtagccgtg gaaaaaaagt gttggaatag
     6541 tggttttttc tatcacttta ctggattctg ccgttttttc tttatcagaa acttcagtag
     6601 tatttatctt cgtcgtctgg caaccactta acgcaaacaa actgataagg actaaagctg
     6661 ctgcagttgc acgtttgcat aaatttttga ttggttctgt catacacctc ttcctttcca
     6721 tatagaaaaa agaaagactt gaaaggccaa tcatatgatc gacatttcaa gtctctttat
     6781 taatcgattt tatctacttg atcgaaatca agttctgtac tggtttcacg tccaaacata
     6841 tcgatgttga ctttcaattt ttctttttct ccgtcaactt ctgttacttg tccttctaat
     6901 ccagcaaatg cgccttcgat gattttcacg acttcgccaa cttctacttc tagatcattt
     6961 tgtcgcaggc tcataccgat agaacgcaag atatgattga cttcttctgg aagtaatggt
     7021 gctggtttgc ttccggctcc gtgtgaacca acgaatcctg tcacaccagg tgtgttgcgg
     7081 acaacatacc atgaagcgtc tgtcatgatc atttcaacaa gtacgtatcc tgggaatgtt
     7141 ttatgaacga tttctttttc tttcccattt ttgacttcag tttctttttc ttcaggaaca
     7201 acgacacgga aaataaagtc ggccattttc atactttgcg cacgagattc gatatttgct
     7261 tttactttgt tttcatatcc tgaatatgta tgcaagacat accagttttt ttcaaaagat
     7321 tccattgaag gctcctcatt tcattgtaaa ataaaaaaac ctcagtacac ccgaagtttt
     7381 tctttcgctt cattatagca ctaaaagtac gttgtggcta gcgagttatt ttaaaatcca
     7441 gccaaataag ctttggatgg ctgtatccat tacgtaaaac atcaatccga aaataataga
     7501 agtttcgatg actactaacg tatctttacg gagttgtttt ctgcttggcc aagttacttg
     7561 tttgatttca tcttttacgc tttttagaaa tttcatgaga caacctccct tgctactgtt
     7621 tatttcgttt ctttatgtaa tgtatattga ttacaatatt tacaaaactt attgatttcc
     7681 aaacgttcgc cgctttttcc ttcactgact gattttgtgt agttgcgaga cccacaaacg
     7741 gaacaagcga gtgctgcttt tttctttgcc atttacttct gcccccttgc tgagaatcag
     7801 acttatactt cataacagta tcacgtaact ttttacttgt caatttgtga aataaactat
     7861 ctattgtttt ggataaaatt atgatatgat taatttgaaa ttaagctaaa atgagacaat
     7921 tggaggtata gcgatgctat taaaaacact tgtatataag aaaaaagatc tgacaaccgt
     7981 tacagagact agtacattag aagaagcatt aaaaatttta gaaacttccg gataccgttg
     8041 tgtgccgatc ttagattctt caggtaatat tttccgtgga aacatttaca aaatgcatat
     8101 ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct gtcactcatc ttttgaaaaa
     8161 cgctacaaag ttcatttacc tggatacttc tttcttcaaa gtattcttta cgatcaaaga
     8221 gcttccttat attgctgtcc ttgacagtga aaatcatttt tatggtattt tgacacatag
     8281 tacgttgctt aatatgctct ctcaatcttg gagcgtagaa caaggaagct atgtactgac
     8341 aattgcttcc acaggaaagc aaggagattt ggctgctatt gcaaaaatca tttcaaaaca
     8401 cagcagcatt gccagctgta ttactcttga tatcgaaaaa gacgaataca ttcgacgtac
     8461 attgatcacg ctaccggcta acactgaagc gaaagtatgt gaaacgatcg tcaaccactt
     8521 agagaaaaag aattataaag tggtagaaat tgaaaatttg caaaaccaag aagcataatc
     8581 aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt tcgcttttta taattagaca
     8641 cgcttttcaa aatcaagcgc gcgatctaaa taatacatca atggtgctga aacagccatg
     8701 acgataaact cacttaatgc aagcgtgcca taggttgtcc aaaatgcttg gccacctgtt
     8761 ggaactaaca tataagcaat cagtcccatg ctgatggtaa agaagatcgt gttcaatact
     8821 aaacgcatct ttacattttt cactttgttt tgcaataaag ctgtcaggcc taaagaaagc
     8881 aatgtttggc cgccaccaaa aaccacatcc atgataccaa aaccaaagaa ggcattatag
     8941 acgatgaccc cgcctaaaac tccccaaagc aatttacggt taaagacaac taaatgattc
     9001 aaactttctg aaatacgaaa ctggatcggc cctgaggata caggcgcaac taaaatagtt
     9061 aacgctagat aaagagccat gatgatgcca tttacaacga ttacggataa ccgttgtctg
     9121 cttttcgttt tttgcatttt ctctcctctt ttctcctagt ttttttaacg cgggatggtt
     9181 gatgaaccgc ggttatgtga aacaaacaat aattataaca gacttttcat ttatttcaat
     9241 ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat gtaaacgttt gctaaaaatc
     9301 gtgggatatg gtataaagta agtgtaaggg gtcataagaa ttcccagtaa agcagacgaa
     9361 gtaggatctg caagaacaga attgttgtga aacttaaata aataaaaaag gatgtgggaa
     9421 tttgagcaac ctcttactag agaacggtct agcaagcagc tgaagatcta agtggacatg
     9481 ccgaaccttg gaacttctcc ttacgtaagt aatggatcat gcgcttgcta ggcttttttg
     9541 tgtttttcgg tcttcggacc tttttcattt tcctagactt ctgctataat aaccaagaat
     9601 taattttgta acagattttt ttgaaaaaac aagtttcttt cattcaaaaa atagaaaaag
     9661 cttgctaatt attggttaac cagcaaacag gagtattaaa atatcttgtt ttattgaata
     9721 gcaggaggaa atcatgaaat tccattatca tatattgatc aatccatcgg caggcagcgg
     9781 aaatggctat aaagtagcag aaagaatttt accggtatta aaaaataagc atattgacta
     9841 tacacttcat tatagtgaat acaaaggaca cgatgctgag attgctgaaa ctttggcaaa
     9901 agaaacattg attccttgga tagaagaaga acagaaaaca atcgatactt tccccctttt
     9961 gatcatcgta ggaggtgacg gcaccttaca tcaggtactt gatactttct atcagatgga
    10021 agtagaattc ccagttgctt atattccagc aggttctgga aatgattttg ctcgaggggc
    10081 aggccttcca aaaaatccca aaaaaggact tcagctgatt ttagcagctc aatcaccaga
    10141 aaaagtccac ataatggctt atgaagaaaa aataagtgaa aaaaaaggaa tagctgttaa
    10201 taatttcggt ataggattag atgcagctat cgtccatgcg acaaatcatt cttccacaaa
    10261 aaagcgattg aacaaataca acttaggatc attttcgtat ttattctcta ttctccgtgc
    10321 tttattcact caaaaaggat ttccaattct ggtagatgca ggaggaaaac aattaagttt
    10381 ttcaaacgca tttttatgta cagcaacgaa gcatcctttt tttggcggag gaatcgcgat
    10441 tgttccaact gctgatgcgt ctaaaccagt cattgatttt gtcgtggtcg aacgaatcaa
    10501 tttctttaaa atcttgtggc tcattctttt acttatacag aaaaaacaat tgaaatcgaa
    10561 atatttccat cactacacaa caaacagatt acgtatcgtt tcaacaacac cgcaacatgg
    10621 tcaagaagat ggagaagaaa tggaaaaacg accttttgat atcacaataa ccacaactaa
    10681 acagttgttt tggtgttaat aaaagaggtt ttgtcagaag ctacatctgg aacaccgttt
    10741 attcggaaaa aaggactgtg acacgacttt tgtcacagtc ctttttttac tatgcagtta
    10801 attctttgcc caattgggtt gccatcgata gtttctttct ttacccaaaa taaattggat
    10861 cattgaaaac accgcagcaa aagcaactaa gacacaacca ttgaaccaaa aagattctgc
    10921 aaatgtttga ttgtaactga gtgtttcact gatcaagtta ttattttgaa caaaccaata
    10981 tgttggtgtg aatgccgcta ttttgctaac catttctggc aagtattctg ctggtacaaa
    11041 caccccaccg ataaagcaac tgcctgtgat aaaaatatct ttgatcccac cgctggtttc
    11101 tgagtttttt accaatgaag tgatacaagc cgaaaagcta atgatcggca ataaaaacaa
    11161 gaaagtattt aaaatatgat accataccgt tatatcccac gaggtgtgga tcactaacag
    11221 aaccattaga agtaagaagc cactgaacaa cagcagcgag taactaatca aactaaaggt
    11281 tactttgcga ttcaagtttc gtttggtaat gggcgcactc tggtttcgtt tactgatctc
    11341 tttgcgatta aacgctagat tgatgacgct gaaaccgcta aaaatggata gaaacaaccc
    11401 ataagacaag aaattaaagg ttgtgcccgt caacagcttt ttcatccgct gactatatcc
    11461 cgcacttagc tcaacttctc cagtaaccga gagtgccatt tgtgtctgtt ccatagctgc
    11521 atcgattgtt ttatcttctt cttgaaacag aatcagtgtt tgcaaaaagg tgttcacttg
    11581 ctgtgtaaca actgttttag aaaaggcatc tgggcgactc tgtatcttga tcgtcgccat
    11641 ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga tgtaagataa tgtttacacg
    11701 attaaaataa agagcatcat cgatttcttt ttgtgaggtt ccatccaatg taacgactgt
    11761 ttccttgtca ttcaaatatt tacgaaggcc atcgactaca ggcgactctt cttcactaat
    11821 caaggcgatt ttcgcatctt gcagagaggt attttcaaca tcaatatttt gcgcaaaaaa
    11881 gaatgtggca acaacagtga taattacacc tatcagtaaa ttcgatttat ttgctttaag
    11941 caatgtccaa atcgttttat aaagcgtcat aacgcacccc tctttccatc caagcatttc
    12001 ctaacgcaaa aaggaaaata aatccgatca accatagaag attggtataa aaactagcca
    12061 aatcagtgta gaaataaagt ttatacaaac tttcgctgat caagttgacg agatttaatt
    12121 gaccaacaat cggaatatga agatcaatcc aatacttcac ttgttccgac cccatcatac
    12181 cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat gctatccttt tgcaccagat
    12241 tcatttttgg tatcaaatta ccaaccaatg tacctaacaa aatcgcacac aacgacccca
    12301 gagcggtaac aatcatcaac cattgccaac gttcaccaaa gtctacttga tagataaaac
    12361 gaaagacagc taacataata taaatctctg tcaaaacaat cgtaaagctt gctgccaaat
    12421 tagcgattga aactaacgat tgctttctag gaatcaagga caagcgaata ccatttgacg
    12481 attgatttgc ttgctgatcc tgtacattgc ggacccccca catcgtcccg tagagaatcg
    12541 ccattccaat cagagtgaag aaataaaaac ttttgaaact catattacga cctgcatgaa
    12601 cttcttgaaa agatacttct tgttcaaaaa cagtcatgat gggcgcgaga tcaacgttct
    12661 ccacttctgc cactttactc gaaattatac caatacgctg taaaaattga tccatgacgt
    12721 ttttcatcaa cgtctgactc attcctgctt gacccacatg gagcgaaaca gatgaaccat
    12781 caatgagata aaaaccagcc aaatcatctg catttagctt ttcattcgct tctacttccg
    12841 atagttcctg tacttcaaat aatggtttat cattgacttc gacttgttct aagactgtgg
    12901 taaaattttc cgaaagcgct gtttgatccg ctttgattac aattccagta ttaatcgttt
    12961 caagattgcc accttgatca atctcgccaa aggccgccat aaacatcaat cctaaaagaa
    13021 ttggaaaggc caatgtccaa aacaacatgg atttatttcg cagcagtatt tttgtgcgat
    13081 atttataaaa atgccaaaac attatttccc ctcctctagt ctctcaaatc cttgccagta
    13141 atctctaaaa agacatcatt caaggacgct tctttggttg ctatttttcc gtaactgatc
    13201 ttttcttctt gtaagattgt aagaatcggc aacaatactg tatttagttc agtagttgtt
    13261 acttggagct gacctttttt ataagcgatt ccatcagaag ctattgttcg ctgaatcgct
    13321 gacaacacat tttctgggag taatgggatg tcgatcgtca aacgatccgc cgtccgtacc
    13381 atatctttta gagattcttt ggttccttta gcaatcacct gtccttgatc catgatcacg
    13441 atctggtcgc aaagaatttc tacttcttcc atgtaatgtg ttgtatagac aatggttgct
    13501 ccttgtcgat tcagctcctt gatactttct aaaattttat tccgactttg ggggtctaca
    13561 gctactgtcg gctcatctaa aaaaattaac cgcggcttgt gggcaatccc acatgcgatg
    13621 ttcaaccgac gtttcaagcc accactaagt tctcctggac gaaacgaaac atatttttct
    13681 aatcccacta attgaatcac ctcttcaatc aaggctttcc ttttctcttt ttcggaaaca
    13741 tataaaccgc aaaaataatc gatattttct tgcacactta gttcgtcaaa gaccgcaacg
    13801 tcttgaggaa cgaccccaat cattgccttg acagcataat tttcaggagt cattgttgtc
    13861 ccgaacaatt taatggttcc tttgtcataa tttaacaaag aaagcataca gttgatggca
    13921 gtcgatttcc cactgccgtt tggacctaac agacctaaga cttctccttc ttgtacttgc
    13981 agatcaaaat gattcaatgc tacaaaatct ccatagcgtt tgactaattt atcaatttcg
    14041 ataatcatca tgaaaaactc cttccaaatt tcttgttgat ctgactataa taaagtgcaa
    14101 gaaaagaaac tagtgacgat tggctaaacc acacatgaca tttgtcacaa tgaaggagtc
    14161 tgctatgcat aaatctcggc tactcaacga aactagcttt ctactggtta tctcattgct
    14221 tttgctggta agtcaaggat tcgttgctat gcaagttatc tatttattga tcgccgtttt
    14281 attcactggt gtcagttatt tactgcctac aaagccaaat tggattttcc aagttattct
    14341 atttctttta tgtgcctttt tacctgatct tgtcctgttt ctgccagcga cgatgcgagt
    14401 gatcgcccct gaagaaagcc accttgatta cttgtttttg ttaggttttt tgttgatttc
    14461 gacggttggt aatcatcccc ccatcaaggt cgcctttgtc gtaattttgc tgtttttttc
    14521 cttttactta cgaaaaaaag atcaacgaac gaccgatctt gagaaaaagt acattgtctc
    14581 caaagatact cattgggaaa aacaacaaga gttatcggaa caaaataaag cattggccct
    14641 gtcacaagaa acacaattag ccttgcaaat tgtggaagaa cggaaccgaa ttgcccgaga
    14701 catccatgac aatgtcggtc atctgctgtc aagtgcgatt ttacaaattg gtgcgcttga
    14761 aatgatcaat caagaaccaa aactaaaaga accattagaa aatttaagtg ccaccgttca
    14821 cactgggatg gatcggattc gtcaaagtgt ccatgacctc catgagacat cgatctcttt
    14881 tcaacactcc ttagagtttc tgatcgctga ttttccttct tctgttacga ttgaaggaaa
    14941 cttgtttgaa ggattgaatg aaacgcagca aaactgcttc ttaatggtca tcaaagaagc
    15001 cttaaccaac agtatcaaac atagtcatgc caaaaccgtt gttttacatt ttcgaacgtt
    15061 gccggccttt tatcgcttgc aaatcacgaa tgatggcacc agcccacaaa aaaattctgc
    15121 tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa gaacaaaagg gacaagtcca
    15181 tattttccaa gaaaaccagc aatttcagtt aacgatcatt ttaccaaggg agggacacca
    15241 atgataacag tagtcattat tgatgatgat ccatttgtga cgaaatcgtt acaaaccatt
    15301 ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc attgtgccaa ggatgcgcta
    15361 gtcttatacg aaacccatcg tcccgatgtt ttgctgacgg acatccgcat gcctaaacaa
    15421 acgggcatcg atgctgccaa agaaattttg gctaaatttc ccaaagccat ccttttgctt
    15481 ttgacgacat tcaaagatga agaatacatc cgcgaagcat tttccatcgg tgtcaaaggg
    15541 tatttaatca aacagaactt gcaagcgatt attccttctg tcaaatccgc ttataatgga
    15601 caggccgtat ttggtaatga aatcatcgag actttcactc aaatgatgaa gaataaaccg
    15661 acgattgata gtcatgctta tgcttctttt agtgaacgtg agcttgcaat catcaaagaa
    15721 gtagctgccg ggaaaaacaa taaagaaatt gcagatgcct tgtacttgag tgacggcact
    15781 gttcgcaatt acatcagcca attactagaa aagctagatt tacgggatcg cacgcaattg
    15841 gctatctatt tttatcagca tttgcaataa gtcttatcta acacaaaaaa acctgaatga
    15901 tgctccttcg catcattcag gtttttttca catcttctat tcaattgtcc cgcaaaccat
    15961 ttcctcacga ttgaaagaat caaggattcg cagggctgcc aggattcgtt ggattgttcg
    16021 gcgtgttagg cggaaaaata ggcgccttgt ctaacgtttt ttctagtttt gattcttcac
    16081 gatcgtctcg ttctacatca ggactttcat tcaatttgaa ttctttttcc atctcatcta
    16141 actttttaaa gtcattgcca gattcttttg ctaatttcgc taatttatct tcggtttctt
    16201 tagccataaa gtaacgcccc ccttttgatt tcagcttagc atatcacact gaaaaaacaa
    16261 aagaaaacgc taaccaacga tcatttttag ctatttctca tctttaaaat caagcatttt
    16321 ttgccggtat aaaatcgtag ggagaactgt tttccatacc aatcatcgga tctactaact
    16381 ggttatcgat cacttctgct gtaagaacga aatctttaga aacagcaggt tctacctctt
    16441 ctttcttttc ttctccaaca aatgaagaaa acagatctgg ttccactgtt tccattactt
    16501 ggtttttcgt ttcattcgtc ccactgtcat cttctacagg tagcttttct tttacaaccc
    16561 gtggctcttt tgtatagttc ccatcttcaa atggatcatt tccgaccaaa gaatcttcat
    16621 aagctgctag tttggtccgg agagtgatat tcattttatc attatccatg atccttgatt
    16681 tcaacgtagt catccggctt gctgattcat tcgctacaca agtgacatag gcttgctctt
    16741 cccctaacaa aatcaacagt tccttactgc gagtcactgc cgtgtagagc aaattacgct
    16801 gaagcatccg ctgatattga tggaccatgg gcaaaataac catcttgaat tcactgcctt
    16861 gtgatttatg gattgagcaa caataagaaa gagtgatttt attccattcg tttcttttat
    16921 aagtgacctc atttgcatca aactggataa ctaattcatc cactttatct tcagaatctt
    16981 ttgccaagat gatacccgtg atttctccca tatctccatt gaatacattc aattcgggag
    17041 tattgactaa ttggaggact ttgtctccta tccgataaac ggtgtcgttc caatgtactt
    17101 ccttttttcc aggtttccct ggattgaata tctcctgcat cattttattt aacgcatcga
    17161 tccctgcagg tccccgatac attggtgcta atacttggat atcttgtgca cggaatccct
    17221 tatttttcgc tttttccaca attttagaga tcaagggttc aatttgataa gcatcacttc
    17281 ggaaatagga acgatctttt tgattctttg tgaaatcttt tggcagacgt ccttctttga
    17341 tctcatgggc aagaggaata atactagaac catcaccttg ccgataaatc tgattgagtt
    17401 ccattttggg aatttgttcg atttccaaaa gatcatggag tacttgacca ggaccgacag
    17461 agggaagctg atctttgtct cctactaaga taacttgcat attcgtcgga atcgctttga
    17521 ataatgtgtt agccagccat gtatcgacca tagacatctc atcaacaatc aaaagtccgc
    17581 cttctaattc tttcgtactg actgaaggtg ttttttcccg tccattcagc cccagaagac
    17641 gatggatcgt actggcaggc agacctgtcg tttcgttcat tcgtttagct gctcggccag
    17701 ttggtgctgc aagtagaata ggaaaaattt cttgggtata ttttgaagga tccaattcca
    17761 gtccgttcaa ctctgcaaaa agattgacga ttccgttgat cacagtagtt ttccccgtac
    17821 ctggtcctcc tgttaaaata aatagagggg aacggattgc ttcagcgata gcttgttctt
    17881 gcgaaggtcc atactgtatg ccgaatattt tttcgatacg ccgaatattc ttctgcactt
    17941 ctttttcagg ataatggatt tcttttttac gactgagaag gcgctggatc gaattaccga
    18001 tcccccattc agaaaagtac aaactgtttt cgtaaagatt agtctcttct tgttgtatct
    18061 ttccttcttc aacaagttgg ataattacag tagcaacctg atcaggctgg atttcaattg
    18121 ggcgacttgt ttctaaaata cggatcgttt gctgaagcaa tgtctccgcc ggtacgtatg
    18181 tatctcctgt ttgaactgca tgctgaaaaa tctgatgcaa gatagctgct cgaattcttc
    18241 tcggtgaatc tgctgcaata ccgatttgtt cggctagatt atctgcacgt ttgaacccga
    18301 ttccttctat gtcttcgact agctggtacg gattttcttc gatgatatcc aaagactcgt
    18361 tcttataggc ctggtagata ctgaaagcta actgactacc gaacccgtaa cgattcagtc
    18421 ccatgatcac ttgatccatc ccgtggttta gccgaatcgt ctcagcaagc atttctcttt
    18481 ttggcttcgt caaaccggag atttgtttta ataccgaagg atcagcaatg attttttcga
    18541 tagcatcttc tcccagcaat tctacaattt tttctgctgt tttcttcccg attcctggga
    18601 atttttcgct ggaaagatac gctacgatcc catttgcagt tgttggcttt tcttgctcat
    18661 atctttcgag tttaagctgc cttccgtatt taggatgatc cactaattct ccataaaaac
    18721 gataagtctc attttcttga atatcgccga aacttccggt gactacaatc tctttttcac
    18781 ggtaatcagc tgtggtttca ctgatgtgta ccaaaagcac tttgtaaaaa ttactaggat
    18841 tttgaaaaaa aatcgcggca actgtaccaa cgaaataagg catttcttct ggctgcatcg
    18901 gaagccgcct ccttcttcta tagtaaaggt tctggtgctg tttcagttcc taaaaaatct
    18961 gtttggttcc atactttcag ttcatatggc aataatctgc aaggctcttc agtctctaaa
    19021 atcgtcaaac tactattgaa caatccaccc atttcacgca actcacttag ctcttttcct
    19081 gtcatccatt gaatggctgc agttaaagaa gctccatgtc ctacgaataa aagtgggcca
    19141 tctttatgtc gggcaaccgc atctgctaca acagtttcga tacgtgtgat tgccgattca
    19201 atcgtttctc cgtgaaaagg agaaggatca tacagatcta aatgattacg caaattcggc
    19261 agattatccg gatatttctg gtacatttca tcgatcgact gaccttctaa agtacccagc
    19321 cctagttctc ttagcttatc tgtataaaaa atctctaccg gacgagcaag ctctttgttg
    19381 ataccttctg ctgtatcacg tgctcgcttt gctgtactgg aataaattgc tttaaaagga
    19441 acatatttta cctttttccc aaatgctttg atttcttcgt aactttgtgg caaaagcgga
    19501 gaatcgccat tgctcccttg aaaacgtctt tcctgattcc attgtgtctt cccatgtcgg
    19561 gtaaaatata gttccatacg cagcaaactc ctgtctttct tttattttac tctataataa
    19621 actgtctaat ccagcttgtc attttcatag tgatgcgtca attctaaatt agggaatcct
    19681 tgctggcgaa gtgcttcata cactatcatt gcagctgtat tcgataaatt caatgagcgg
    19741 acatgctcat cattcatagg gatgcgtaaa cacttttctt cgttttcacg cataaatgtt
    19801 tctggcaaac cggttgtttc ttttccaaat aaaaagaagt gctcttctcc atcagcaaaa
    19861 ttttcgtcac tatatacttt atgggcaaat tttgagatca aatgtagttt acgattacct
    19921 aaaaatgtta aaaaagcttc taaattactg tggtaagtaa tatttacatc attccaataa
    19981 tccaaccctg cccgttttag atgtttgtca tcagttgaaa aacctagtgg ctcgattaaa
    20041 tgaagcggag tattcgtggc tgcacacgta cgggcaatat ttccagtgtt tgcagggatt
    20101 aatggttcaa ataaaacgat atgattcatc aggatcattc ctctcatatt tatgttcgtt
    20161 tctattttct gacaatttga tttttgcata aaaaaaaacg tatcaactcg gtgtcagtca
    20221 ctgcgagtcg ttacgttagt gaagctcttc tcactaactt ttatcagaac aggaacctga
    20281 taaaaaccaa tgaaaaaaca acttgttgct aatataacac cctcaacttt tttttgcaac
    20341 ctctactcat taaaaactgc tagaaaaacg ttttctctta gttcctttta ataattctat
    20401 gtcaattgta atcttcttca aaggattctt atataagtct gctttgattc gctcttctac
    20461 ctgccattct aaaggtgaca tggccaaaag atctttttga ttttcctctg gtatctcaaa
    20521 ttcataggtt acacgctgac gttcagttaa tttcattgct tcagcaaact tggctactac
    20581 acgttcattg gaataactct gtttttcagg ttgattcgga taaaaagcct gacgtagttc
    20641 ctttaaataa ttttcttgtg gcaccacctt caacacttct ccatcttctg agagtacacg
    20701 ttggaattct tggtaatgag aaggcgaaaa gatatttaaa accgcgttga atgtttgatc
    20761 agcaaacggc aaattggtca aatcagctac acaccaaaat gcttcggcag attgttctgt
    20821 agctgcgtag actccttctt ttgaaatatc aaatccaaca gcattttgaa tctttttcaa
    20881 ttttgaaagt tcattcaaga agctaccttc tccgcagcca acatctaata gcgagacttc
    20941 ttcaggtaaa tgctgcgcaa tagtctcaat aacgggctga tacatgccag attggatcat
    21001 tctacgcctt ggaacgaaca ttccttgatc gtattctgtt ttaaccgcat gggataaaaa
    21061 ataaagtgtt ccttttttgg aaaggtcaaa acggtgatta tttttgcata tcaagccatt
    21121 atcagacttt tttacttctt cttggcaaac cggacagcgg aacagctgat gattttctgc
    21181 caaaaactgg cgtcctcggt caattttttt taacatagtt ccccctcatt tctgttttat
    21241 cttaccgtta gatgctcact ttggcaactg ctaaaaatat gatacaatgc ctagaagaaa
    21301 gtgaaagata aaggagaaga ttagatgatc aaagaatttt gcgctgaaaa ctacacatct
    21361 attcctctag caattgctag aggagccgat cggatcgaat tgtgtgacaa cttagcggtc
    21421 ggtggcacaa ccccgagtac tggtgtgatc gaagaaacgt taagttatgc tggggaaaaa
    21481 gatatccccg taatgacgat tattcgtcct agagggggcg acttcgtcta taacgatatc
    21541 gaattgaaaa tcatgcatac tgatttgatt gaagcaaaga aattagggac ggatggcgta
    21601 gtatttggtt gtcttactcc ttcaggctgg ctagacgaag aggccttaga actattgatc
    21661 gaaacagcag aagggttgca gatcaccttc catatggctt ttgacagtat tcctgaagat
    21721 cggcaattcg aagcaatcga ttggctggta gaacatggtg ttgaccgtat cttgactcat
    21781 ggcggtcctg ctgacaaaac tattgtagaa aatttcccac ggcttaaaga attgattgcc
    21841 tatacagatg gccgcttaat cattttgcct ggtggtggtg tcactgcaga gaatgcagca
    21901 catgtagcta aagaattgaa cgtaagcgaa gtacacggaa ccaaaatcgt ggatcttcag
    21961 ttataatctt ataaacaaaa aaacatttgc aacaggcata atgcttattg caaatgtttt
    22021 tgttttttta cataaaatag cccataaata aagaagcaat attgaaataa atcagtacac
    22081 tcgtcaaatc gctcaaagtc gtgataaagg gaccgcttgc tactgctgga tcaaatccta
    22141 gacgatccat tagcatcggg attaaactac ctgcaagatt cgccactgtg attgcaaata
    22201 gcatagccat ccctatgaca aaccccaaga taaaattatg tttccaaaaa cctacgatta
    22261 gaaaaatcgt gatccccgta acagctcctg tgacaacgcc ggtcaagact tcagccaaaa
    22321 caagtcgaac aaatccatga tctttctcat cagaaatcgc aagtcgacga acagccacag
    22381 ctagcgactg ggttccagca ttaccggcag ttcctgtaat cagcgaaatg aagactgcta
    22441 aaatactcgc ttcacttacc aagtcttcat agtgactgat taaagaagcg gtcgacatac
    22501 ctaaaaacaa cagagtgatc agccaaggca aacgtcgaga cgctgccttt actggatttt
    22561 cattaatttc ttccacattg accccggcaa gtcctgaata atcgctagca gcttcatcat
    22621 caataacgtc gatgatatca tcgactgtga cgattcctaa caaatgatca tcataatcgg
    22681 taacaggaag agctaagaag tcataatctc taaatgtttg tgccacatct tcttggtcgt
    22741 cgcctacatg aactgaaagc actcgttcgc tcatcagatc agaaatcatt gcgtcgtcat
    22801 cattcacgat taggtcgcgc agagaaataa cccctactag ctgaccttct tgattaacga
    22861 catagatgta atagattgtt tcagctacat ctgcttcgtt cttcagcacg tacatcgcag
    22921 agcgaacagt ttgattggct acgatcgaaa caaattcagt tgtcatgatc gcgccagccg
    22981 tttcatcctc gtaatggaga agttccttga tttcactggc atcgtctgcc gacatcaaac
    23041 ttaaatattt agcaatttgc tttttatcca gcgtattaag caagtcaaca gcattatctg
    23101 tatacatctc agaaagcata tcagctgcat agctaggacg catttcatct aggtattctt
    23161 tcatatgttc gttgtcttct tcaatcacat cgaacatatc cgctaattct ttaggcgaca
    23221 gataggaata gatcagctgc ctgttctctt ctgtaagaga ttggtagaat tgcccctgct
    23281 catagatatg catctctaaa aaactgtttc tgaatgcctg aatattattt tcccttaaat
    23341 cttgagtcaa ctgggcaaat ctttcctcta attcttgatt ttcatccaaa ccaatctcac
    23401 ctcgccttat tcttcaaacc gtctcacaac tgcctccatg tctgcggcta aaggctgctt
    23461 gaactccagc aactcttctg taaatggatg gtaaaaacgc agatcataac aatgaagggc
    23521 ttgtcttttt attcccagat ccattcgccc gccatacata tcatcaccga gcagggcaca
    23581 gccaattgcg gaaaaatgaa ctcttatttg atgtgtcctt cctgtatgca gctggatatc
    23641 aactaacgcg atttctgtta gtcgcttctc tatccagtac tcagtctgtg ccgaacgtcc
    23701 ttcatcagag accattcgct tcaatagcga agaataatct cgggcgatcg gcaaatcgat
    23761 atgtccatgt gccgataaat ctgaaagcct tccactgact aaggcctgat attttttcac
    23821 aaacttcttt tcacgaagtt gcatatctaa ttttgcgtgc gcaaatccat gctttgcaaa
    23881 aagcatcaag ccagatgtat cccgatctag tcgcgtcacc acatggatta cttggttttc
    23941 gtaaccttgt tttttataat aagcctttac acgattagcc attgtcccat ttggatggta
    24001 ttgggcagga atagacgaaa cgcctgctgg tttatttact accagaacgt gttcatcttc
    24061 atacacgata tcgatcggtg tttcatccaa aagtacggtt tcatgttctc cttcagcagg
    24121 aatcacaatg gttaccttat catccttagc tagagaaaac aagacatttt ctacttgatc
    24181 attaactttg atttgaccgc cttgaaattt tattttcgct aacagaccct ttgagatccc
    24241 tttttctttt aaaaaatatt ttacttgctg agaatgatct ttctcataat cccatgtaaa
    24301 ctgcatatca atcctcacta ataaaggcat ctttcacacg atgccaaaaa tgcatatgtc
    24361 gataagaagc aaaatggatc cgttcttctg ctattcgata ataaattgag cggatatttg
    24421 cttttgcgac attcaattga tcaaccgtta caagataatc ttctgtattt tccaatttta
    24481 tttctagcca ttcatcatgg gcaatcacga tcggagaacc caaagtacga aacactcgat
    24541 tattcagtga agcaatctct gccaactgaa aggcattgat actaggatgg atcacagcac
    24601 cgccgacact tttattatat gctgtcgaac cagtaggcgt agaaatcgtc aatccatctc
    24661 ctctaaaact ttcaaacagc tcgtttttga tgtatacatc ggctaccatc gtacgattgg
    24721 cccgtttaat cgttgattca ttcagtgcta aaaaatgctg gtccggtgtt tcatccaaat
    24781 aactgatccg aacatccagc aagggataac taacactttg ttcccggttc gttcgtaagc
    24841 tgtctactag ttcttccagc tcgtaatccc gccaatccgt gtaaaaccct aaatgacctg
    24901 tatgcacgcc caagaaacgc acatcattca gacaatgact gtagtgatgg aacgccgaca
    24961 ataatgtgcc gtctccgccg actgagatga ccaattctgg ctcatgatca tctcgttgaa
    25021 tccctgcttg ttctaaaagt gcgttcaaac gttctgtcac ttctatagtc tttgcttctt
    25081 tattatgaac gatcgctact ttcatcccct gcctcctctc tttcgctttc tttcttcaaa
    25141 agcgttcgat agtagacatc atctgatttt cctcttccat gggagaataa ccgctgtgct
    25201 tcttggattt cttcacggat actggacatc tcttcatcca actgataggc agcttctgcc
    25261 gcacgctgaa gtcgttcact catttcttct ggaaaaacgc cttgatattt ataattcagc
    25321 gaatgctcaa tcgttgccca gaaattcatc gcaagagtcc gaatctggat ttccgccaaa
    25381 attttcttct caccgctgat cagctgtaca ggatactcga tcaccagatg ataagaacgg
    25441 tagccacttg cttttttatt tgtgatgtaa tctcgttctt ggagaacttt catgtctttt
    25501 cttttacgga tgatctcaac aacttgatgg atatcttcta caaactgaca catgatcctt
    25561 aacccggcaa tatcagacat ttcttcttct aaacgtccca ttggaatatg ccgtaattgt
    25621 gattttgtta caatactatc gactggcttg actctcccag tgacaaattc aatcgggaca
    25681 tgtcgatttt gttcacggaa ctgtttgcgg atcccccgca gtttcacttt caattctgat
    25741 acagtttgtt catatggtgc taaaaatgct tcccaatctc gttccatagc tgatacctct
    25801 acttcattaa cattcattgt ttattctacc atatatgcaa agttttttcg tactcttgat
    25861 ttatgcattg accaaaaaaa gaaaattagg caaaatagac aaaaaggagt cgatcaaatg
    25921 acacaaatgc ttgaaatcga atataaatct atgctgacaa agcaagagta cgagatattc
    25981 atcgctcact atcaattaac agataaagat ttccgtgtac agactaatat ttatttcgat
    26041 accgttgatg aacagctgaa gaaacaaaat tgtggcctac ggatccgttt cgttggtcat
    26101 caagctgaat atacattaaa aacacctgct gaaaaagggc gtctcgaaac aacggatacc
    26161 tttataacag aagaagcaga agcatttatc ttcgaaaaac gtctgcctcg ttcaggcgca
    26221 gtttttcaaa aactttctga tttgaatatc gatcctgctt cattaatcca aaccggaaag
    26281 cttacaacaa aacgagctga attccctatt gaagaaggac ttttagctat tgatgaaagc
    26341 tggggagaca atctacacga ttttgaactg gaactagagg taggggatgc atctgtggga
    26401 aaaattgctt ttataaattt tttaaaacgt ttttctttac cttatcgtcc tgctaagaac
    26461 aagatccaac gtatgcttga agctaaaaat tagaaacctt tcattttcac aaggcacttg
    26521 agttcatttt tttacttttt tctgttaagt tataggatgt gaaagaatct agtcactagt
    26581 tgtatagaat ctattttggg ggagattcat atgatcgaaa tctatttatt tgttaatcct
    26641 ttaggggaat actgtttcga aatggaacaa cagttattac aatttatcga agaagagtac
    26701 gggacaccat caaaagaaaa gatgcaattt cgctttcttc ctttggtcaa tttgcagaca
    26761 attggggatg tcatgcaaca aaaaggaatt tctcagaaca atcttgagga acgtaatcac
    26821 ttattctcaa tgacttattc tgcagcattg gactgcaaag cggcgcagtt tcaaggaaag
    26881 aaaaaaggcc gccgtttttt gatcaaattg caagaagcag tcggctgtaa tgacatacca
    26941 tattctcaag aacttgctga atccatattt gaagaaatcg gcggcgattt gaatatgttt
    27001 aaagaagatc gtcagtctga cttcgttaaa gaagtattct tttctgatca aaaaattgct
    27061 cgggaaatgg gcatcacaaa acacccttct gcagtcgttt acaattatgc ctgcgaccgt
    27121 gattttggtg ttttagtaga agtaaaaggt acaagtagcc tttggagaat cacagagctg
    27181 tgtaaaacaa cagataactc atatcaagtt tttaatggtg aacatttaca tacaaatgat
    27241 tctcagttcc attcaagaac tagccattta cacttgcttt ctaattaaaa aaggctcttt
    27301 gtcaaatgat gttggtaaag agaaatctta gaata
//
LOCUS       DAFEIE010000034        25812 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFEIE010000034
VERSION     DAFEIE010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.035"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            128..3655
                     /locus_tag="LP345_001632"
     CDS             128..3655
                     /locus_tag="LP345_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBL1760417.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3652..7374
                     /gene="addA"
                     /locus_tag="LP345_001633"
     CDS             3652..7374
                     /gene="addA"
                     /locus_tag="LP345_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBL1760418.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7443..7784
                     /locus_tag="LP345_001634"
     CDS             7443..7784
                     /locus_tag="LP345_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1760419.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8093..9136
                     /gene="pheS"
                     /locus_tag="LP345_001635"
     CDS             8093..9136
                     /gene="pheS"
                     /locus_tag="LP345_001635"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBL1760420.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9141..11561
                     /locus_tag="LP345_001636"
     CDS             9141..11561
                     /locus_tag="LP345_001636"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBL1760421.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11731..12741)
                     /gene="trpS"
                     /locus_tag="LP345_001637"
     CDS             complement(11731..12741)
                     /gene="trpS"
                     /locus_tag="LP345_001637"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBL1760422.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12995..13732
                     /locus_tag="LP345_001638"
     CDS             12995..13732
                     /locus_tag="LP345_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1760423.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13746..14561
                     /locus_tag="LP345_001639"
     CDS             13746..14561
                     /locus_tag="LP345_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL1760424.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14574..15221
                     /locus_tag="LP345_001640"
     CDS             14574..15221
                     /locus_tag="LP345_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1760425.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15237..15893
                     /locus_tag="LP345_001641"
     CDS             15237..15893
                     /locus_tag="LP345_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1760426.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16055..16876
                     /gene="racE"
                     /locus_tag="LP345_001642"
     CDS             16055..16876
                     /gene="racE"
                     /locus_tag="LP345_001642"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBL1760427.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16879..18234
                     /gene="rph"
                     /locus_tag="LP345_001643"
     CDS             16879..18234
                     /gene="rph"
                     /locus_tag="LP345_001643"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBL1760428.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18235..18753
                     /locus_tag="LP345_001644"
     CDS             18235..18753
                     /locus_tag="LP345_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL1760429.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18860..19360
                     /locus_tag="LP345_001645"
     CDS             18860..19360
                     /locus_tag="LP345_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1760430.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19640..20560)
                     /locus_tag="LP345_001646"
     CDS             complement(19640..20560)
                     /locus_tag="LP345_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBL1760431.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20725..21738
                     /locus_tag="LP345_001647"
     CDS             20725..21738
                     /locus_tag="LP345_001647"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBL1760432.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21848..22603)
                     /gene="fabI"
                     /locus_tag="LP345_001648"
     CDS             complement(21848..22603)
                     /gene="fabI"
                     /locus_tag="LP345_001648"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBL1760433.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22823..23263
                     /gene="fabZ"
                     /locus_tag="LP345_001649"
     CDS             22823..23263
                     /gene="fabZ"
                     /locus_tag="LP345_001649"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL1760434.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23378..24139)
                     /locus_tag="LP345_001650"
     CDS             complement(23378..24139)
                     /locus_tag="LP345_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1760435.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24328..25422
                     /locus_tag="LP345_001651"
     CDS             24328..25422
                     /locus_tag="LP345_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL1760436.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25508..>25812)
                     /locus_tag="LP345_001652"
     CDS             complement(25508..>25812)
                     /locus_tag="LP345_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1760437.1"
                     /translation="ITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGIL
                     RRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         8543 a         4475 c         5441 g         7353 t
ORIGIN      
        1 gcgtatactt aaaaaagtag aaatatcaga accttaaaag gatataattt gaagaatata
       61 gaacaaatgt tcagtatttt ttgatataat aaaggagcac cgtatcatgt gttgaaggag
      121 gaaaagcatg tctttacaat ttattcttgg aaacgggaaa aaagatcacc gtcaagtctt
      181 gatcgacgaa gcatccgctt ggctcgacca ggatgcaagt aaccaagtat ttttccttgt
      241 tcccaactac agcaaattcg aacaggaaca agaaatttta gcggagatgc gaagaagaag
      301 cggaaaaaaa actttcagca caacaaacgt tcaagtattt agtttttatc gtctggcttg
      361 gtatttgctg caacagacaa ctcttcttac aggaaatgaa ttatcagaat caggatctgc
      421 aatgatcttg cgacagattt tagaaaaaaa tgaggaagaa ttaacaatct ttcgcggaga
      481 aatcaataaa agagggttta ttcgtcaatt acaagaactc tacagtgaat tgcgtacagg
      541 aaatattcaa ccagaagacc tgatgctttt atttggtgat tcacctaatg cagaagacca
      601 gcaacttaaa atgaaagact tgaagctgat tttttcagct tatgacagcg aattgactca
      661 acgtgcacta acaaatgaag atgcactatc tatactagca aattatatgc agacacaaga
      721 tttcaacaac gtcaaattta ttgtcagtgg tttttctcga atcaatggtc aagagtatca
      781 attactgcag gcaatgatgg aaaaggggca attggttgtc gatttattgc tggatcgtcc
      841 ttatacagcg gatcttccag aagtacttac gctctttcat gagactggaa agctttattt
      901 ccgtcttttt caaagtgcaa gagaacggaa agtccctata ttagtggacc gatttgcacc
      961 agagcagact cgtccgacag agcttcaact gctgcaaaca atgtgggaag agacatctag
     1021 ccaaaagaaa gcggcagtac acaaaatagg gggacaagag catctccatt tgtgggaagc
     1081 tgaaaatcca actgaagaag tccgacaatt agctgttgaa atcagacgac tagtcagtga
     1141 agaaaactac cgttatcgtg atatccaagt gctgacaaaa aatatgtctt tatatggaaa
     1201 tatccttcgg ccgatctttc aagaaatggc aattcctttt tatatcgatg aagaacaaat
     1261 gatggaaaat catccgctga tcgaatggat caacagtctg ttcgctcttg accgctattc
     1321 ttatcggcta agtgatatta tgcgtttttt caaaactgaa ttatttctgt cgacggaagc
     1381 agaaaccgaa cttgatgaat ggaaacaaga gcgagatgaa ttcaggaaaa aactggacat
     1441 cactgaaaat gtagcacttg cttacaatta tcaaggaact tattggactc gtgaaaaaga
     1501 ctggcagttt gtggcgtatg attttgaagc agaacagatt gaagacgtac agtatttgga
     1561 agaacagtca aatacgatta gacgattatt tcagaaagct gtaccagtat ttttgaaaaa
     1621 aataaagaaa agcaaaacag gacaagaggc cgcaaatgtt ttttatcaat ttttgatcca
     1681 aagtggcgta cagcaacaat tattgttttg gcgtaatcag gaagtagaca gaggaaactt
     1741 agaagcggca agaaaccatg agcagacatg gggagcgctg attgatctgt tggatgaata
     1801 tgtagtaatt tatggtgaat cggcttttga ctggtcactg ttccaagaaa tcattacaag
     1861 tggtctagaa aatctaagtt atggtaaaat ccctaccgca atcgaccaag tgcgaatcaa
     1921 tcgtttggaa ttagttcgac caaatcaagc tgccgtcact tttgcattag ggttgaatga
     1981 tcaagtgttt ccagaccgaa aagagacaaa aggattgttg tccagtgaag aacgagaagt
     2041 attaaatcag gccttgccag atggacagtt tttattcgac ccatcaaagg aaagtatctc
     2101 ttttgagcct ttccaagcct atcttgtttt tctttccgga acagatcgat tatatcttag
     2161 ttatgcacaa agctatgaca cagatggttc gctgaagatg tctccttatt tgcgtagaat
     2221 cacagaatat ttatctgttc ccgtcgagag aaaagagcat ttgacgatcg aaagcgaccc
     2281 taattgttat gtagggactt acagaagcgg aatcaataca gtcaatagga tttatcgatt
     2341 agctttagat gaaaaaaaac ctgtaccaaa gcactggcaa aagctcaaag aattagtact
     2401 gaattcgtca tggcgaaatt ttgctttaca gatttttgaa agtcaggaac atttaaatgt
     2461 tcctgtttcg atgccagaaa aaatggcgga agagctttat ggaaaagaga tttatacttc
     2521 aatttcacgt atggagaatt tttataattg tgaatacaaa tacttcatgc aatttggttt
     2581 gaaattgaaa gaacgaactg tttatggtct aactccagca gcaactggtg atttttatca
     2641 tgaatcattg gatcgtttct tcaagctact gttttcaaac caattatcct tagtgaatat
     2701 gtccgatgcg cagcgtagag actttactga aaaagtgctg caggaagtat tcggagaact
     2761 tcggtttgag atattggata gttctgcaag aatgaactat atccgctacc agttaggaca
     2821 gacgattcaa aaagtgacat gggctttgca aaaacagagc aaaaatacag gcatgcatcc
     2881 tcttcagaca gagattctat ttggtcagat tgctggagca aaaggtatca caggtctgga
     2941 attaccgttg agtaatggtg gaaaactcca tgttcgaggg aaaatcgatc gaatcgatgt
     3001 agcttctgaa caagaagata cttggctaag cgtcgttgat tacaaatcta gcggacgttc
     3061 attcgatgtc acagaagctt attatggcat ggctatgcaa ttattgacgt atctggacgt
     3121 agcattgatg gatgcggtac gtttgactgg aaaggcggct gttaaaccag caggatcata
     3181 ttatttacat gttcataatc ctgtattgac ggagacagat gatgtagaga agaatacatt
     3241 gaaaaaattt agttatgatg gcgtttttgt cgatgatccc gctcttttag aagtactaga
     3301 tcattcactg gaagcaaaag aacaatcact gatctatcca gtgaaaaaaa atgcgaaaga
     3361 tgaataccaa aaaggtagtt tcagtaaaga caaatttttc acggaagaag aactgcaact
     3421 attcatggcg cataatcggg aaaatatgcg gttagctgga gatgcgatta cttccggaga
     3481 aatcaaacta aatccagctt ataaagataa acagcggatt gcctgcgaat tttgtccatt
     3541 cagaagcatc tgtacgtttg atgtgatgct gaaagaaaat aattaccacc gtctggagaa
     3601 aatagataag gaagaagcac tgcgtagaat attgaaaagg agtgaagaag agtgaatcaa
     3661 attcctttaa aaccgcaaaa tgaacgattc acagatgatc agtggcaagc gatttttgat
     3721 caaggagata atctattagt ctctgcgtct gccggatcag gtaaaactac agtgcttgtt
     3781 cgaagagtga ttgaaaaact aaaaatgggt tttgatatcg atgaattatt gattgtgaca
     3841 tttactgaag ctgccgcaag agaaatgaaa gaaagaattc aagaggcatt acaagaatcc
     3901 gtcaatagcg aaagtgaccc tgtacgtaga cagcatttta ctaagcagtt agttttattg
     3961 cccacagcga atatctcaac cttacatgct ttttgcctga cagttattcg acgttattat
     4021 tacttaattg atattgatcc agtctttcgc atgttaacag atgaaacaga aacgatcttg
     4081 atgaaggagg atgtgtggga cgagctgaga gaagcacttt atgcagaaaa tgatgaacga
     4141 tttttccaat taacaatgaa tttttctaat gatcgttcag atgacggctt gacgaatctg
     4201 gtgttttctc tttatgagtt tgcccgtgcc aaccctgacc cccaaaaatg gctagaacag
     4261 ttaagcgata attatcgttt gcctgagggg ctagcgaaat ctcgattata tcaaaaacaa
     4321 atccgtcctt tagttttggc agatatatac caatgtgtac agttatatga acagatgact
     4381 cagttagcac aaggtgaagg attagaaaaa atgcatgagc aagtagctgg agaacaacag
     4441 cagatcaaga atatctatga agcgttctcg caagatcggt tagaagaagc ttatgctggt
     4501 ttggaacaac taactttttc aacttttaag agcagtcgga aagcagaatt gaaagaaatt
     4561 tccaatgaag tcaagggcat gagggataaa gcaaaaaaac tgattcagca gataagtaaa
     4621 agttattttc ctgtttcccc aagccaaatg gaagaattaa cggacaaagc actaccgtta
     4681 gtcgaagaaa tgacaaaagt cacgcaaagc ttcatggacg gtttcagtat gcgtaaacgg
     4741 gaaaaaggtg tgctggattt caatgatctg gaacatttag cgttgcagat tctcacagaa
     4801 aaaacgaaag atgtatggct gccaagtgaa gcttcaaaac attatcgaaa aaaattcaaa
     4861 gaagtaatgg tagatgaata tcaagacgtg aaccaattac aagaagccat tttatactgg
     4921 ctaagagaac ccgatgatac aaaaggaaat atgttcatgg ttggggatgt caaacaatcc
     4981 atctattctt tccgtttagc agatcctagt ttatttatcg ggaaatacga gaatttctca
     5041 aagaaagaag gcggacgtcg aatcgttttg gctgagaact tccgctctag aaaagaagtc
     5101 ctttctttta cgaatcttat ttttgaacaa ctaatggatc cagcagtggg tcaaatcaat
     5161 tatgacgaag cagccaaact gatccaagga ttttcagact ttccagagaa tgaacagttt
     5221 gagccggaaa tcatgatcta tgaaaaagaa caggaagaat cagagattga gattccgacg
     5281 gatgatatac tggaagacaa aacagaaggc gaacttttta tgacaggact aaaaattcgt
     5341 caattaattg attcctcctt tatgatttat gataaaaaat caaaaaaaag tcgtccgata
     5401 gagtacaaag acattgttct cttgacacct acaaagaaga acaacttaac gattttagag
     5461 attttcaaaa cattggatat tccattagag atgaatgatg ctcaaaacta ttttcaagcg
     5521 acagaaattc gcacgatgat ctcgctgcta caattaatcg ataatcccta tcaagatatt
     5581 ccgcttgcgg ctgtattgcg ctcaccgatc gtgggtctga ttgaaccaga attagccagc
     5641 attcgattag ctaaccgtgc acatacttac tatgatgctg tgcttgctta tcaagcatca
     5701 aacgaagatg aattagcagc taagctggaa cattttggca agcaactaga gcattggcga
     5761 gaacttgctc gccgttcttc gatcactgac ttgttatggg atatctatta tgagacggga
     5821 tatctagagt atgtggtcgg tctgccagca ggggcacaga gacaagccaa tctttatgca
     5881 ttggttgatc gtgccaaagc ttacgagcaa agttctttca gaggattata ccagttcgtg
     5941 cgtttcattg aaaaaatgca agaaaaagat aaagacttag cagaaccagt catttcaata
     6001 gaagataatg ctgttcgcgt tatgacgatc catgcaagta aaggcttgga attcccagtt
     6061 gtatttttgt tagatatgac aaaggagttc aacttacaag acttgcgcaa tcggtatgct
     6121 tttgaagaaa aacttggagc aggaattcgc tatatggatc ctgaaacacg agtgttatat
     6181 gatacgttac cgtttcaagc catcaaattg gcaaagcaaa acaaattgtt gtcggaagaa
     6241 atgcgtaaat tgtatgtagg attgactcgg gcagaacaaa agcttttcat tgtcggttcc
     6301 tataaaaata aagagcaaat gatccaaacg tggtctgaag cagctgatca tgaggagtta
     6361 gtttttgatc ctgcgctacg tttgaagggc agaagcagct tgatgaattg gattggttac
     6421 ggattgatcc gtcatcctga aatgcagaaa tacttagagg aagaaatttc gacttctctt
     6481 cttcaacatt caaatgcaca gttttctatt tcatggatga atcagcaatc gatcattgaa
     6541 caaagacagt tgcttgctga aaaagaactg gttaacttag atcagcagat gaaagaagat
     6601 gaaactttat tagcagattc gttacaaaaa cgtctggcat atgaatatcc ttatcaagct
     6661 tcttcacaaa ccacaagtta tcaatctgta tctgaaatca aacgattatt cgaagatcca
     6721 gatgatacac aagaatcacg tttgactctg gaaagcagtc agaacaaagc agcatcccgt
     6781 caatttcgtt atacgcaaga acaactagca gaaccaaaat ttttgcaaaa agatcggcaa
     6841 gtgtcagcag ctgctgttgg aactgctacg catgctttgt tacaattact gccattagag
     6901 atgccaacta cagagagtat ccatcaaaaa ttacaggaat tggtaaggaa acggttagta
     6961 gacgaaaaag tcgcgaaaaa agtagatgtt tcttctatta tatggttctt tcaaacagaa
     7021 cttggtcaac agctgattgc caacaaagaa aacgtaaaac gagaacaacc tttttccatg
     7081 ctgcttcctg ctgacgaagt atttcaagac tatccaaatc aagaagatga actattaatc
     7141 cacggaatcg tcgatggata cctagaagaa aaagatcatc tcaatatcta tgattttaaa
     7201 acagatttta ttttacatcc ggatgatcca gcagaaatag atgcaatcgt ccaaaaatat
     7261 caaggacagc taagacttta ccaacaagca atgtcagaag ctttgaataa gccagtagaa
     7321 aatgttttcc taattttgct tcgagtgaaa caaattataa acattaacaa ataattataa
     7381 ttgagcaaac ttgacttatg ttttgtaagg attatgctat actctgggaa gaggtgagta
     7441 tgatggagct aacacagaca gaattcgttt tatgccctaa atttgaaaaa acattctcta
     7501 ttttaggaaa aaaatggaac ggattgatta tcgatgtact actcgaaaac ggtccgcaac
     7561 gctttgttga gcttgcggca aaaatcccga tggtcagtga tcgagtatta gtcgaacgct
     7621 tgaaggaatt agaaaaagaa ggaatagtca ctcgaaactt tgcctgtagc gaaaagagcc
     7681 gttcagaata tctcttgact gaaaaaggag cagacttgca aaaagcgatg cgtcaaatac
     7741 aagtttggag cgaaaaatgg atcacagagg aagaatgcgg ttgattttgt aaaaaaaatc
     7801 ttgtaaacta tagtccatac gaataagtaa agaacgatga cgaaaaagag tagtttggct
     7861 aaaccagttc agggagatct gtcgcagact gaaagcagat cctgtgtttg aaaaatgaag
     7921 ttcactttcc gagttcgtct gataaaatca gaccggcaat tgtcgttaac gaagtaagag
     7981 tgcggtgtaa gtcatttatc cgcaaattag gatggtaacg cgaagacctc gttccttaac
     8041 aggaatgagg tctttttgtt ttgtatttgg aatttaaagg aggaacaagc acatgtctct
     8101 acaagcacaa ttagagagct tgaaagaagc aacgctcgtc aaaatcacag cggcacaaga
     8161 tttaaatgaa ttaaatcaaa tacgtgttga aacgttagga aaaaaaggac cgatcacaga
     8221 agtattacgt gggatgaaag atctaagtcc agaagagcga ccaaaagtcg gaagtttcgc
     8281 aaatgagatc cgagatcttt tgacagaaga gatcgagcga aaaaaacaag tattagaaga
     8341 agaagcgtta aatgcagctt tggcaaaaga aacaatagac gtgacactac ctggtagaaa
     8401 agtaaaacat ggtacacgtc atatcgtgac acaaatcatg gaagaaattg aagatatttt
     8461 tgtgggtatg ggctatcaga tcgtagaagg atatgaagta gaatctgatc attacaattt
     8521 cgaacggatg aatctgccaa aagatcatcc agcaagggac atgcaagata ctttctatat
     8581 ttcagacgag atattgattc ggacacatac ttcaccagtc caagcacgga caatggaaaa
     8641 acatgatttc tctaagggtg ctctacgaat gatctcgcca gggaaagtct tccgcagaga
     8701 tacagatgat gcgacccaca gtcatcagtt ccatcaaatt gaagggctag ttgttgataa
     8761 aaacatcaca atgggcgacc ttaaaggaac attagaagtc gtaatgaaaa aaatgtttgg
     8821 ggaagatcgt gaaattcgtt tgcgtccaag ttatttccca tttacggaac catcagtaga
     8881 agtagatgtc agctgtttca aatgtggtgg tgccggttgt aacgtatgta aatacactgg
     8941 atggatcgaa attttaggag ctggcatggt acacccgaat gtgttgaaga tgtcaggaat
     9001 cgatccagaa gaatattcag gctttgcttt cggccttgga ccagaccgcg tagctatgtt
     9061 gcggtatgga gtgaatgata tccgtaattt ctatcaaaat gacttacgtt tcttaagtca
     9121 gttcaagggg gagtaagaaa atgttagttt catataaatg gctcaatcgt tatgtagatt
     9181 tatcgaatgt aacaccaaaa gaattagcgg ataagatgtc tgtgacagga atcgaagtag
     9241 agggagtaac ggttccagaa gaaggcttga aaaaaatcgt tgtcggtgaa gtcaaggaat
     9301 gcgtaccaca tccagattct gatcaccttt ctatttgtca agtcgatatt ggcgaagacg
     9361 aactgtctca aatcgtttgt ggagcgccta atgtgaaggt tggaatcaaa gtgattgttg
     9421 cacttcctaa ctcacgtatc gctggtaatg taaaaatcaa aaaaggaaaa atgcgtggcc
     9481 aagtatcaaa tggcatgatt tgctcattac aagaaattgg ctattcagat agtgttatac
     9541 cgaaagaata cgctgaaggt atctattata tgccacaaga agctgtaaat ggcgatccag
     9601 tttttcctta tttggatatg gatgattcga ttattgaatt atctatcaca ccgaatcgtg
     9661 cggatgcatt gtcaatgcgt ggcgtagctt atgaagttgg ggcaatttat cgtcagactc
     9721 ctacattcga tgacgaaaag ctggtagaat cctcacgtcc tgctagcgat aaaattcaag
     9781 tggaagttga agataaagaa gcagttcctg cttatcaaat cagaatcatt gaaggagtaa
     9841 gaatccagcc aagtcctcaa tggctgcaaa atcttttgat gaacgaaggc attcgtccaa
     9901 tcaacaatgt agtagatgtg acgaactata ttttgctttt attcggacaa ccactacatg
     9961 catttgacta cgacaaattg aaatcaaaag agatctttgt ccgccgtgca aaagaaaatg
    10021 aaacattagt aacactagat ggagaatctc gggaattgac aactgacaat ctcgtcatta
    10081 ctaacggcaa agaaccagtt gctttagctg gtgtcatggg agggttagac tcagagatca
    10141 cgaatgaaac aacaacagtt gcactagaat ctgctttatt tgatccaatt tcgattcgtc
    10201 gtacagcaaa acaatttaat ttgcgtagtg aatcctctgc acgttttgaa aaaggaatca
    10261 accatgcgac tgttggagaa gccagtgagg ttgctgcagc aatgatcgtt tctcttgcgg
    10321 gtggggaagt tctacaaggc gcggtcaaag gctcagagat caaagcagaa gacgtatcag
    10381 tgaagatttc acttgaacgc atcaatcaat atttaggaac atctcttgtc gttaaagaag
    10441 taaatgagat ttttgaagca cttggattta gctatgaaga aaaggagtat gtttattccg
    10501 tagtagtacc accaagacgc tgggatatcc aaatcgaagc agatattatc gaagaagttg
    10561 ctcgtattta tggatacgac cagttgccat ctacacttcc aagtggagaa acggttgctg
    10621 gaagcttgtc aaaagaacaa gaaactactc gtaaaattcg tacaatcttt gaaggaagcg
    10681 gattgagcga agcaatcagt tatgcattga caacagaaga aaaatcaaga cagtttgtta
    10741 taaatgaaag taatattaca cgtttggact ggccaatgag cgaagaacgt tctgtattac
    10801 gaatgaattt gatcagcgga ctattagatg atatcagtta taacactgcc cgaaaaaata
    10861 cagagattgc tttatatgaa attggtcggg tgttcttcca agaaaatgat ccacgtacac
    10921 atctgccgca agaagtaaaa catgcagcaa tcgctatttc tggtatttgg gaagaaaaag
    10981 attggcagac gaaagctcaa aatgtagact ttttcaccat caagggtctt ttagaaaact
    11041 tatttgaaca actaggcatc actgaagatg tccattatca aacagtgaca gaaatgaagg
    11101 aaatgcatcc tggaagaact gctgcgattt accttggcga aaaatttatt ggttttgtcg
    11161 gtcaagtgca tccaacgatt acaaaaagtt atgatattcc agaaacatat gttgctgagt
    11221 ttgatttatc tgctatagtg gaagctgctc aaaaagggat cgttttcgaa gcagtgacaa
    11281 aattcccagc agtcagccgg gacatcgctt tgcttgtaaa agaaactgtg acaaatcagg
    11341 aattaacaga agttatccgt tctgctgccg gaagattttt aacagatatc caattatttg
    11401 atgtctatca aggagaaaac attgaaaaag gacataaatc catggcgtat agcctgacat
    11461 tcgtcaaccc agaagcaaca ttgacagatg aagaaatcaa taaagcaatg gaaaaagtcg
    11521 aaaaagcgtt ggtagaaaac ctagaggcaa gtattcgcta agaaggaaaa tatagtaagt
    11581 aacgatcaag tagcttttga agaccataca tttgaaaaaa agatgtgaca caacttcgtc
    11641 acatctcttt ttttgatttt aaaaaaggaa tagcacagag acgagataaa aaaacaggcc
    11701 tttacagcct gcttttttag agtaaatgaa ttaatggaag taattgattc ccattgctga
    11761 ttttacttca gaaagtgttt gtgcagctac tttagcagct tcttcactac ctttacgtaa
    11821 gatttccata acagctgaag gatctttttc caattcttct cggcgcgcac ggatcggtgc
    11881 aaattcagct tccaatacat caatgaggta tcgtttgatc tttacatcac caagtccgcc
    11941 gcggcggtaa tgagctttca tttcttcaat tgcttcttta tctgttccga atacatccaa
    12001 gtaggtgaag accatattcc cttctacttg tccaggatct tgtacatgga tgtggtttgg
    12061 atcagtatac atactcatga cttttttctg taagacatcg gcaggatcgg agatataaat
    12121 accgtttcct aacgatttac tcattttgcc atttccatcg attccaggta atctacccat
    12181 tccttttggt gggaatacgc cttttggttc caccaagact tcaccatatg tatgattgaa
    12241 gctttgtacg atttcctgtg tctgctctag cattggtttt tgatcctcac caacaggtac
    12301 aagattcgct ttgaatgcag tgatatctgc tgcttgagaa acaggataga taaagaatcc
    12361 tgtaggcacg ctttcaccga attttttttg ttcgatttct gttttgacag tcggattgcg
    12421 ccgaacgcgt cctacgctga ctaagttcaa ataatacatg gttaattcag ctaattccgg
    12481 aatttgtgat tggataaata aagtagattt tgcaggatct aatcccacgg ctaaatagtc
    12541 taaagcaact tgcaagacat ttgatgaaac cttctcagga tttttagcat tatctgtcag
    12601 tgcttgcatg tcagcaatca tgacaaacag ttggttgtct tcatctgcct gcatagccac
    12661 tcgggttttt agagaaccga cgtaatgccc taaatgcagc ttcccagttg gtcgatctcc
    12721 cgttaaaata atatttttca aaaaagacac ctctttacga tttgtaagtc tgagcactta
    12781 atatcttacc gtttttcctg aaaagaaaca acagttccta aggaaaaaac aaggaaagag
    12841 gataaaataa ctaatagatt agaaatggaa gaaatattta tgggagaata aacgttctaa
    12901 gaaactttac aaattactaa actatcagat ataatgtatt ttattataca tctttaaaag
    12961 aaatcttact aaataataat gggagtgtaa ttctatggca atgattaaat ttgatcacgt
    13021 ggataaatat tatggcaagt tccacgcatt aaaaaatatc aatctcgaat tcgagaaagg
    13081 agaagttgtc gttgtcattg gtccttctgg ttcaggaaag agcacgatgc ttcgctgtat
    13141 caatggatta gagacgatct cttcaggtaa gctgctgatt aatgatactg acttgcatga
    13201 taaaaagaca aaactgacag aagtccgaaa aaacatcggc atggttttcc aacatttcaa
    13261 tttgtaccca aataaaactg ttctggaaaa catcaaatta gcaccaatca aagtgttgaa
    13321 gcaagaccag gcaactgcag tcaaaaacgc ggagaaattt ttgaaaactg tcaatatgtt
    13381 agataagaaa gattcttatc cttccatgtt atccggggga caacagcaac gggtggcaat
    13441 cgccagaggt ttagcgatga atcctgagat gctgctgttt gatgaaccta cttctgcttt
    13501 ggatccggaa atgattggtg atgtattaga cgttatgaaa aaattggctc atgacggtat
    13561 gtcaatgatt gtcgtgacac atgaaatggg ctttgccaaa gaagtggcgg atcgtgttat
    13621 cttcatggct gatggagaag tattggaaga cagcagaaat gtgagagact ttttcgaaaa
    13681 tccaaatgaa gtccgagcac agcaatttat cagtaaagtt atcaatcatt gataggagga
    13741 aaaagatgcg caggttaaaa aaaatacgcc tgattttcct tttaggcatt gcttttcttg
    13801 cactagccgg atgtaaagga aatgggttgg caaatgaaga tattttagag cgaagcaaat
    13861 ctaccaatga aatcatctgg ggtgtcaagt atgatactcg attatttgga atgatggata
    13921 ttgagagcag aactgtacaa ggatttgatg tagatattgc aaaagcaatc actaaaaaga
    13981 tccttggtga caatggaaaa acagaatttg ttgaagtcac ttctaaaact cggattccat
    14041 tattgaaaaa cggaaatatc gatgcaatta ttgcaacgat gacgatcaca gatgaacgaa
    14101 aaaaacaggt tgacttttca gatgtctatt tcgatgctgg ccaagctttg ttggtaaaga
    14161 aaggaagcca aatcaaaagt gtagatgatt tgaatgcttc tacaacggtt ctagcagtca
    14221 aaggttctac atcggctgcg aatatccgac agcatgcacc agatgcaaaa attttagaat
    14281 tagaaaacta tgcagaagca tttactgctt tacaatctgg tcagggagac gcgatgacta
    14341 cggataatgc gattttgtta gggattgcag atgaaaatcc agagtatgag ttagttggtg
    14401 gaacgtttac taatgagcct tacgggattg cgatcaacaa agggcaagaa aacttcttga
    14461 aagctgttaa ccaagcgcta gaggaaatgc atgcagatgg cacatacgat aaaatctatc
    14521 aaaaatggtt tccaaatgaa actgaaggaa aagtagagta agggggagag gcaatgagcg
    14581 aattgataca aacttatgga ccaatctttg tcgacgggtt caagatcaca ttgttttcga
    14641 gtgtcttagc acttgtgttt agtttgatta tcggaacgtt aatggcaatc ttccaattat
    14701 caaagaataa agtagtgagc gccttagcaa aggcatatgt agaatttttt agaaacattc
    14761 cattattaat catcgtgatg tttttttatg ttgtcgtacc gatttattgg tttaatctag
    14821 atggattcca agcaggtacg attggattaa cgatctatac atctgctttt attgctgaaa
    14881 cagtacgttc agggattcaa accgtaccaa aaggtcaaac agaagcagga ctatcttctg
    14941 gttttaccta ttcagaaatc atgcgttata ttgttttacc gcaagcattc aaaatcgtta
    15001 tcccgccatt aggcaaccaa tttatcaacc tcgtaaaaaa ctcatctatt ttagcaatcg
    15061 tagctggttt agatttgatg tatcaaggag acttgatcgc tagtgaaaca ttcaatacct
    15121 tcgatacgta tatcatcgtt gggttatttt acttagttat cacgctaccg ttatcttact
    15181 taatggttta tcttgagaaa aaatgggcgg ttcgttcata gaaggagggg aaatacatgg
    15241 attttagcgg cgctttttca tggatgaata tccgtttttt attggaagga ttaaaggtta
    15301 ctgttgaagt ttcattgttt tcgatcattt ttagtttctt gatcggtggt ctgacaggtg
    15361 tgattcgttt tgcgaatatc cctttctttt ccaaaatcct tggtgtagtg attgatatta
    15421 tacggaatct tccattatta ttgatcattt tcttcactta ctttgcctta cctcaaatcg
    15481 gcattcagat gaacatcttc tggtccgctg tcgcagcatt aacgattttt gagtcagcta
    15541 tgttgtcgga aattttccga gctggactca atgctgttcc aaaaggacag atggaagcag
    15601 gattatcaac gggactgact tatgtagaat cgatgcgaac gatcgtgtta ccgcaagcat
    15661 ttaaatcaat gatcccggca attgtgagcc aattgatttc actgatcaaa gatacttcat
    15721 tagcagtaat catttcttta cctgaacttt ctcatcaggc acgtattatt tatggacaga
    15781 acaccaatta tgtgcttccg atgttcatca tcatgacact tatgtacttc gtggtatgtt
    15841 acgcgctttc tctgctttcc ggttacttgg aaaagagacg gtacagttat taatagatga
    15901 ttcttttagc ggttgtggca aactaaagtc acaaccgctt ttcctctttc cattcgaaaa
    15961 aaagagattt cgattgtttt aagcaagtaa gagcacttga aaattcacgc taaaaagtac
    16021 acaataggga ggatagaatt tattgaaaaa aaggatgata cgattgacag ataatcgccc
    16081 tatcggattt attgattcag gtgtcggcgg cttgactgta gtaaaagaag ccctgaaaca
    16141 attaccgaat gaaaatattt tatttgtagg agacacagca cgctgcccat atggccctag
    16201 acccgcggaa caggtaatcc agtatacttg ggaaatgacg gattatctgg tggagcaagg
    16261 aatcaagatg ctggtgatcg cctgcaatac cgcaactgcg gtggctttag aagaaatcaa
    16321 agctgctctt tctattccag tcatcggtgt gatccttccc ggtactagag cggcagtaaa
    16381 aaaaacacaa aataaacaag ttggcattat cggtacgatt ggtacggtaa aaagtcaagc
    16441 ttatgaaaaa gcactgaaag agaaagtacc agaattgact gtgacaagtc ttgcttgtcc
    16501 caaatttgtt tcagttgtcg aaagtaatga ataccattca tcggtggcga aaaaaattgt
    16561 ggcagaaaca ttagctcctt taaccactaa aaaaatcgat acattgattt tgggatgcac
    16621 ccattatcca ttattacgcc ccatcattca aaatgtaatg ggagaaaatg ttcaactgat
    16681 cgattctgga gcagaaacag taggtgaagt atctatgctg ttagattatt tcaatttgag
    16741 caattcaccg caaaatggtc ggacattatg ccagttttat acaactggct ctgccaaact
    16801 tttcgaggaa atagctgaag actggcttgg aatcggacac ttaaatgtag aacatatcga
    16861 attgggagga aaataaggat gcgtcatgac gggagaaaag cccaagagct tcgcaaactg
    16921 gagcttcaaa caaatgtttt caaatatcca gaaggatcgg tagtgatccg ttttggtgat
    16981 acaacagtta tttgttctgc aacaatagaa aattctgttc cccctttttt gagagaaaca
    17041 ggaacaggat gggtgacagc agaatatagt atgctgcctc gagcaacgag tacgagaaat
    17101 cgtagagaaa gcagcaaagg gaaactttct ggtagaacaa tggaaatcca gcgtcttatt
    17161 ggtcgttcct tgcgtgcagt agtagacttg gaaaaattag gagaacgtag tatcatcgta
    17221 gactgcgatg tgatccaagc ggatggcggt actagaacag caagtatcac tggggcattt
    17281 gtggcattga aattagccat tgaaaaactt ttaagagaaa aagaattgtc agaagatcca
    17341 ataaaagaac atcttgctgc agttagcgta ggaatcttac cagatgggac ttgcgtcaca
    17401 gatttggatt accaagaaga ttccgcagca cttgtagaca tgaatcttgt aatgacagaa
    17461 tctggaaaat tcgtggagat tcaaggaact ggagaagaag caacgtttga tggtgaacag
    17521 ttgaatgaaa tgctcttttt tggaaaaaac gcgattgaag atttgatcaa agagcaaaaa
    17581 catgctttgc taacagagtt tgctcaaaat gatgagcgga tagaagaaac aaaaacaatc
    17641 atcattgcga caagaaatcc aggaaaagca gaagagtttc gaaatatgtt caaagaagcg
    17701 ggatatcatg taaaaacatt acttgactat cctgaattgc cagatgtgga agaaactggc
    17761 agcacatttg aagaaaatgc ccgattaaaa gcagaaacga ttgcacaatt gcttgatcag
    17821 ccagtcttag cagatgattc aggtttgaaa gtggatgctt taggcggtat gccaggaatc
    17881 tattctgcac gttttgcagg ggaacaaaaa agtgatgcgg ggaataacgc caaattatta
    17941 tatgaattga cagatgtgcc ggatgaaaaa agaacagcac aattccattg tacgttagta
    18001 ttcgcggcac ccaaaaaaga cagccttgta gtagaagcgg aatggcccgg tcgagtagcc
    18061 cgtataccat ctggcgaaaa tggctttggg tatgatcctt tatttatccc agaaggtaag
    18121 aaacaaacag cagcagaatt atcgagcgaa gaaaaaaaca agatcagtca tcgggctcaa
    18181 gcaatgaaaa aattgagtgc cgagtggaaa caatggctgg aaggagagag atagatgcgg
    18241 tatttagtag taagtgataa tcatggagac agagatatcc tcgttgactt agtagatcgt
    18301 tatcgttctg aagtggatat ctttttccat tgtggtgatt cggaattaga agcttctgac
    18361 ccattatggg atacattcca agtggttcaa ggtaattgtg attatggacc aggattcgaa
    18421 cagaaaaaag tgatccaaac tggtcaggat acagtattca tgactcacgg tcatttatcg
    18481 aatgtccgat ttggtttgac acagttagca atcgaagctc gagctgcaac tgccgatatg
    18541 gtgttttttg gtcataccca tcaaataggc tgtgagatgg atcagaaaat cctgtttttg
    18601 aatcctggta gcatttctca gcctagaggc ccgatccaaa tcccatcata tgctcttatc
    18661 gaaagtttag atgaccaaat ttctgttcaa tactataacc gtgcccatca ggcagttgaa
    18721 gagttggcct tttctttttc gagagagcgc tgaataaaaa aactctaatt tttaataaaa
    18781 ataagcttta ttttatgaat tttgcatccg gtttcggtaa aatagtagtg ttgaatgaaa
    18841 tagaaatgga ggccatcaga tgattggacc tatagtaaga gaaatgctgc tggaaaatca
    18901 ggaaacgttt ttgattcctg cagaaaatgt ggcaaatgtt atgtatcatc atccattgtc
    18961 ccatggttta cttgtgttat cgaaggtcgg ttattccaaa attcctgtat taggaaaaga
    19021 tgatcacttt gtaggactag taagtttatc agatgtggtc aataaaatga ttgacttgca
    19081 aacaatcagc atggacccgt tagaaggact aacggttgct gatgtgacag aaacagatgt
    19141 tccgacaatt gatgaaaatt gggaactaga agaagtactc catttgttag tcgattcgcc
    19201 ttttttaccg gttgtcacag aagatcggat tttcaaagga atcattacaa gaaaagagct
    19261 gcttaaagcc gtaaacttca tggtgcatga attagaacgt cgtaatatat tgtctccgaa
    19321 aatcgaagaa ttaaaagaac aaatcgatat cgtgagctaa agaacgagaa actaaaagat
    19381 aatcaaaaaa taagtagaaa aaacagcgta ccagttttga ctttatcttg aaaaagaggc
    19441 tgggacaaaa gcgtttaact ccaagaaata agaaggaatt cacgaaaatt gcttttcaaa
    19501 tttttgtgaa tttcagctta tttccgaagg agttgcttct gcttccgccg tttatacgtg
    19561 tttagagcgt gggacaaaag tgttctttac ttttgtccca cgctcttttt agtgagattc
    19621 gttgcatcgt ttgtccaaat tattttccga cagcaattgg actgttcgga atcgtgaaac
    19681 cagaagctgt caattctttg acataggagc tcaagaactc ttcttttaag gcatattgtt
    19741 ttccgttcaa tgcgtagcag accgtacgaa tcgcaaaatt gctgtttcca agatccacta
    19801 atccaaagat agaaggttca gtttggagct cttcttggta tttttcagct aatgtacgat
    19861 ttactcgatc aatgatctca tagattttgt catatccttc ttcaggaaca atccgaatat
    19921 ctaaaagtac ttgcatattt gcacgagaga gattgctgat cgtggtgatg tttcgattcg
    19981 ggatgaaatg gacagtacca tccgttgctt tcagctgaag ggtacggata ccaacagata
    20041 cgacggttcc ttcaatcgtt aagtttgcta gcttgatgta gtccccaaca tccatctgtt
    20101 gttccatgat aataaaaaat ccggtaataa catcactcat gaacccttgg gcaccaagac
    20161 cgattgccac acctgcaatt ccggcaccag ccaaaagtga tccgatcggc acaccgatag
    20221 cagataaaat tgcatagata aaaaagaaac caagggtata atgaaaaata gtatttaaaa
    20281 gactatgtaa agtctttaag cggctctcgt ttagaatggc ttttttagaa tactgattaa
    20341 aagacttatc aatcagatat tttcccacac ggtgaagaat ccaaaaaagg acgatcaaaa
    20401 aaatcagata taaacttttt tggataaagg cagccaaaat ggcgtcccaa tcaatcccgt
    20461 cccaaaaccg ctgaaacgca tttactttgc tgacagcttg atctgtcaat gtctcgccag
    20521 aagagtctgt cgtaccggca gttgctaata atgaaaacat aaaatcctct tttctaaaat
    20581 ttgattcttt ctgtattgta ccaagaagtt ttcaaaaaag gaaatagcaa aaataactat
    20641 aatgaaggaa aaaagctgaa aataaaatga caaataatat ggataatgat aaaatgtgga
    20701 gaaaataacg aaggtggtaa gtatatgcaa atcgattgga acaatctagg tttttcttat
    20761 atcaaaactc cttggcgttt tattgccaaa tggaaagacg gacaatggga agaaggagaa
    20821 ttgacagaag ataattacct gacgattcat gaaggctctc cagcgcttca ttatggtcag
    20881 caatgttttg aaggtctaaa agcttatcgt cgaaaagacg gcaaggtcaa tctctttcga
    20941 cctgaacaaa atagtcgacg gatgaatcaa agtgctagac gattgctgat gccaatggtc
    21001 cctgaaaaga tgttcgttga tgctgtcaag caagtggtaa aagcaaatga agattttgtg
    21061 ccgccctatg gaacaggcgc tacattatac ttgcgccctt tactgattgg ggtcggtgaa
    21121 aacattggtg tccatccagc tccagaatat ttatttgtcg tcttctgtac gccagtagga
    21181 gcgtatttca aaggtggact aaaaccaacg aattttattg tatctgatta cgatcgtgct
    21241 gctcctaagg ggactggtgc agcaaaagtc ggcggaaatt acgcagcgag tttacttcca
    21301 ggaacagaag caaaagaact ggattactca gattgtgttt atcttgatcc agccacacat
    21361 acgaaaatcg aagaagtagg tgcagcaaat ttctttggaa ttacaaaaga cggaaaattc
    21421 atcactccgc aatcgccctc tatcttacca agtatcacga aatattcctt gttgcagtta
    21481 gctgaagaac gactaggact gcaagcaatt gaaggagata ttttcattga tgatctagat
    21541 caatttgcag aagctggtgc atgtggtaca gcggctgtta tttctccaat cggtgggatt
    21601 tatcacaata acaatcttca tgtattttat agtgaaacgg aagtaggacc agtaacaaaa
    21661 cggttgtatg atgaattgac aggtattcaa tttggagaca tagaagcacc agaaggctgg
    21721 attgaagtcg tggaataatt tcaaagtaat gagttgaaaa aaacgtaaaa agaaaaaatc
    21781 aggaagagac tttaaaaagt tttttcctga tttttatatg ttttacttta aagaatgcaa
    21841 caaaagttta tgaaagatgg acacctttgt caacgtagat aatatcaccg atgattccgc
    21901 tggaaagtgg gctgattaag aaagcacaag cattaccgac ttcttcgatc gtcacacctt
    21961 gctgatcagg cgtacgagat tcagataact ggatcagttt ttgatagtct ttaacacctg
    22021 tgacagctaa tgttttgatt gccccagctg agattccatt gacccgaatt cctttaggcg
    22081 agaactcagc tgccaaataa cggatagcag cttcaagaga agctttcgca atacccatca
    22141 tgttataatt cgggattgcg cgttctgaac ctagataagt catgctaacg atcccgctgt
    22201 ttggtgcaag aaacggttgt gcgtattttg atacagcaat taaagagtag ctgctgatat
    22261 cttgagctaa ttgatagccg tctctggaaa tatcagacac atttccggac aattcttctt
    22321 tgttggcgta agcaactgca tggacaaggc cgtggatctc cccagcatat tcaccgatgg
    22381 cattcattgc tttttcgatg ctttcgtcgc tagaaacatc acattctaca gtgaatgctt
    22441 cttcgccgac caatttgact aatgattttt tcattcgttc attttggtaa gtatagataa
    22501 tttctgcccc ttgtttcaac attgcttcag cacaacccca agcaatgctt tttttgttag
    22561 cgacgcccat aatgacgatt ttttttcctt ctagaaatga cataatgact ctcctttgtt
    22621 tctgataaaa atttgatagt cgtaaaaaaa tagagaataa tagctaaaat aacttcttga
    22681 tttcttaatt attagtcaaa atgttttgat tgtcaaacta ttttttctta aattaaaaaa
    22741 agattgctaa atatttagga atatgatact ttgatagtca aagtaatgaa aatggcaatt
    22801 gcctgaaaga aggagtttaa ttatgtctta cgtattatct gctactgaag taatggaatt
    22861 gattcctaat cgttatccta tttgttatat tgattatgta gatactttag aaccaggaaa
    22921 aaagatcgtt gcgacaaaaa atgtaacaat caatgaagat tttttccaag gtcactttcc
    22981 tgacaatcca gtgatgccgg gtgcgttgat tctagaaaca ctggcacaag caggttcgat
    23041 acttatccta aaatcagaag agtttctagg aaaaagagct tatatcggtg ggatcaataa
    23101 ggccaaattc cgtcaaaaag ttgttccagg agatgtgctg aaatgtcatt ttgaaatcac
    23161 caaaatgaag ggatcagtcg gtacagcgtt atctgcagca tatgtagatg ataaaaaagt
    23221 ctgtgagtgc gagttcacgt tcatcgtcaa ccaaaatgct tgactataaa acctgatata
    23281 gcaaaacaaa aggaagctta cttgcttttt atgtaaaaag aagacgcctg aatcctagca
    23341 tacgttgtca tctatgcagg attcagacgt tattttttta tttttgtttt gcttcttgca
    23401 gtatattgat tttatcgatt tttacttctt cttttggttt gtctgaacta tctgtttcga
    23461 tatttgcaat agcatccacg acatccattc cttcaatcac ttggccgaag acagtataat
    23521 ggccatctag tgaaggataa ccgccgtttt tataagcgtc gatgattgct tgaggatagt
    23581 cgtcttttaa aagaccatca tgcatatcat ctgtattttg aacgataaag aactggctgc
    23641 cgttactgtt aggatcttgt gagcgagcca tagataacgc acctcttata ttataaaggt
    23701 ggttgttgat ctctgtttca aatccttctc cccaaatgct ttcccctcca gtgccatcgc
    23761 ctttaggatc gccaccttgg atcatgaaat ctttgatgac gcgatggaaa gtcagtccgt
    23821 tgtagtaacc gtcttttgca tgtgtcataa agttttcaac cgcttttggt gcgtgttcgg
    23881 gaaataattt gattttgatt gtgcctttat tcgtcaccat ttcgaccaga tcttcatttt
    23941 cggcgacatc tttcgtcaat tgtggtaatt ccaatgcgtt caaatcgacg ctactggcag
    24001 tcgtgctttc cgcagtagat gtactttttg aactttctgt agacgaacta gaagaagtcg
    24061 tgttgtttgc agaacaacca gcagcaaaca gcaatgctgc tgctaaacta atacttaaaa
    24121 taactttatt tttcttcata actgttcctt tccaatttac tattttgtta tctttaatga
    24181 taacaaaata gagggaaaat acctacttaa attattggaa tttatcattt attttaaaag
    24241 aaaaagaaaa ggtgtagacc atttactttg tgtttgctat aatgtaagtg gatacaaaaa
    24301 cgaaaagatg caggaggaaa tggtaatatg ggaaaattag gaatctcgat ttatccagaa
    24361 cggtcaacat ttgaaaagga caaagcgtac ttggatttag ctcataagta tgggtataaa
    24421 cgggttttta ccagtttgct gcagatcaat gatgataaag aaaaagttct ttcagaattt
    24481 aaagaagtag ttgattacgc gaatagccta ggcatggaag taatggttga tatcaatcca
    24541 gcgttatttg aacagttgga gatttcttac gatgacttat cttttttcca taagatgggt
    24601 gcctacgggg tccgcttaga tatcggattc acaggagcag aagaagcaaa aatgacgcgc
    24661 aatccttttg gtatcaaaat cgagatcaat atgagttcgg gcacgaatta cgttgacaac
    24721 atcatgagtt attcgccaaa cacggataat ttattaggtt ctcataattt ttatcctcat
    24781 cgatactctg gtttaggata cgaacacttt gttttttgtt cagaaaaatt cagaaaatat
    24841 aatttgaata cgatggcatt cgtcaattcg caatctgctg agtttggccc ttggcctacg
    24901 caagatggct tgtgcacgct ggaagaccac cgagatcttg aaattgcgac acaagtgaag
    24961 catttaatcc ttacaggatt gattgatgat atttctattg gaaatgcgta cgcaagtgaa
    25021 gaagaattga aagaaatggc agaagcattt aacgcggatt atccaacatt gaaagtagat
    25081 acggaagaag gtattacaga aaacgaacga atctgcttgt ttgataacct tcatagttat
    25141 cgaggggatc gctcagaata tatccttcgt tcaacgatga ctcgtgtata ctacaaagat
    25201 aaagatttcc cgcctcataa tacgcgagat atgcatcatg gggatgtact gattgacaat
    25261 gaagggtacg gtcaatacaa aggagaaaca caaatcgcct tgaaggatat gaaaaacgac
    25321 ggacgtgtca atgttgtagg aagaatctcc gatgacgaat tattcctcct tgactttttg
    25381 aaaccatggt caagctttaa attaattgaa aataaaaaat agataattag ttattgcaga
    25441 aataatccgc tagaaatagc cagttatttc tgctttttta ttttgttttt ttataggtta
    25501 tgatttgtca aattaagcta gaataaaatg cttcttgtac atagctcaaa aatatttcga
    25561 ttggtgttct gtaattcaat gattttcttg gaatatgatt acgttgattg ctgacactgg
    25621 aaataaatgt ctgattcact tttctaaaat ccattgattt cggcagtcca ttacgacgca
    25681 gaatcccgtt agaattctcg tttaatgggc gttgagaagg tgttccaggg tccgcaaaat
    25741 atatatcaat atcatgttgg ttactaatgg ctttccagtt agaaaattct tttccacagt
    25801 caaacgtaat ag
//
LOCUS       DAFEIE010000035        25807 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFEIE010000035
VERSION     DAFEIE010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.036"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            7..849
                     /locus_tag="LP345_001653"
     CDS             7..849
                     /locus_tag="LP345_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL1760438.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            849..1796
                     /locus_tag="LP345_001654"
     CDS             849..1796
                     /locus_tag="LP345_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL1760439.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            1811..2044
                     /locus_tag="LP345_001655"
     CDS             1811..2044
                     /locus_tag="LP345_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBL1760440.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            2375..2959
                     /locus_tag="LP345_001656"
     CDS             2375..2959
                     /locus_tag="LP345_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1760441.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            3090..3757
                     /locus_tag="LP345_001657"
                     /pseudo
     CDS             3090..3757
                     /locus_tag="LP345_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
     gene            3768..5183
                     /locus_tag="LP345_001658"
     CDS             3768..5183
                     /locus_tag="LP345_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1760442.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            5201..5770
                     /locus_tag="LP345_001659"
     CDS             5201..5770
                     /locus_tag="LP345_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBL1760443.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            5880..7634
                     /locus_tag="LP345_001660"
     CDS             5880..7634
                     /locus_tag="LP345_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760444.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            7594..9360
                     /locus_tag="LP345_001661"
     CDS             7594..9360
                     /locus_tag="LP345_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760445.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            9883..10152
                     /gene="rpsN"
                     /locus_tag="LP345_001662"
     CDS             9883..10152
                     /gene="rpsN"
                     /locus_tag="LP345_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL1760446.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            10167..10346
                     /gene="rpmF"
                     /locus_tag="LP345_001663"
     CDS             10167..10346
                     /gene="rpmF"
                     /locus_tag="LP345_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL1760447.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            10378..10755
                     /locus_tag="LP345_001664"
     CDS             10378..10755
                     /locus_tag="LP345_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760448.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            10776..10925
                     /gene="rpmG"
                     /locus_tag="LP345_001665"
     CDS             10776..10925
                     /gene="rpmG"
                     /locus_tag="LP345_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL1760449.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            10949..11932
                     /locus_tag="LP345_001666"
     CDS             10949..11932
                     /locus_tag="LP345_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL1760450.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            11962..12084
                     /locus_tag="LP345_001667"
     CDS             11962..12084
                     /locus_tag="LP345_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL1760451.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            12102..13625
                     /locus_tag="LP345_001668"
     CDS             12102..13625
                     /locus_tag="LP345_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL1760452.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            13649..13888
                     /locus_tag="LP345_001669"
     CDS             13649..13888
                     /locus_tag="LP345_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760453.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(14081..14542)
                     /locus_tag="LP345_001670"
     CDS             complement(14081..14542)
                     /locus_tag="LP345_001670"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1760454.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(14737..14955)
                     /locus_tag="LP345_001671"
     CDS             complement(14737..14955)
                     /locus_tag="LP345_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760455.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            15073..16689
                     /locus_tag="LP345_001672"
     CDS             15073..16689
                     /locus_tag="LP345_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL1760456.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(16930..18270)
                     /locus_tag="LP345_001673"
                     /pseudo
     CDS             complement(16930..18270)
                     /locus_tag="LP345_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18546..18701)
                     /locus_tag="LP345_001674"
     CDS             complement(18546..18701)
                     /locus_tag="LP345_001674"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBL1760457.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(18893..19087)
                     /locus_tag="LP345_001675"
     CDS             complement(18893..19087)
                     /locus_tag="LP345_001675"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL1760458.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            complement(18997..19329)
                     /locus_tag="LP345_001676"
     CDS             complement(18997..19329)
                     /locus_tag="LP345_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1760459.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(19843..20034)
                     /locus_tag="LP345_001677"
     CDS             complement(19843..20034)
                     /locus_tag="LP345_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760460.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(20128..20514)
                     /locus_tag="LP345_001678"
     CDS             complement(20128..20514)
                     /locus_tag="LP345_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1760461.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            21208..22413
                     /locus_tag="LP345_001679"
     CDS             21208..22413
                     /locus_tag="LP345_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBL1760462.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            22430..22864
                     /locus_tag="LP345_001680"
     CDS             22430..22864
                     /locus_tag="LP345_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760463.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            23481..>25807
                     /gene="esp"
                     /locus_tag="LP345_001681"
     CDS             23481..>25807
                     /gene="esp"
                     /locus_tag="LP345_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBL1760464.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         8895 a         3698 c         4830 g         8384 t
ORIGIN      
        1 aataatatgc ttcaaaattt tattaatggt ctgtatgact ttcacttttt acagaatgct
       61 ctaattacat ctgtagttat agggattgtt tctggaacag taggttgttt tattatttta
      121 agaggaatgt ctcttatggg tgatgctatt tctcatgctg ttttgccagg agtagcaatt
      181 tcttatattt taggtattaa tttttttatt ggtgcgattg tatttggtct attagcttct
      241 atcattatta cttttataaa aagcaatagt gtaataaaag gagatacagc aattggtatt
      301 actttcagtt cttttttagc attaggagtt atccttatag gagttgcaaa tagctcaacg
      361 gatttatttc atatcttatt tggaaatatt ttagctgtac aagatattga taagtggatt
      421 acaattggcg tttctgtttt agtgttggtt acagttgttc tattttttaa agaattatta
      481 atcacttctt ttgatccatt aatggcaaaa gcaatgggga tgaatgtcag tttttatcat
      541 tatctattaa tgattctatt aactttagta gcagtaacag ctatgcaaag tgtgggaact
      601 atattaattg ttgcaatgtt aattacacca gctgctacag catatttata tgcaaacagc
      661 ttaaaaacta tgatatttat ttcggcgaca gtcggagcgt gctcatcatt gctaggtttg
      721 ttcattggtt atagttttaa catagcagca ggatcaagta ttgttttaac agcggcattc
      781 ttatttgtaa ttagttttct aatctcacca aaacaaaaat ttttaagaaa gaaggagaga
      841 aagttatgat gagaaaatgg aaagcagtac tgggaagtct ggggattttg attgctcttt
      901 ttatattcgg ggcatgttca acaaatagta aagacaaaga tacagtggct tcgaacgaaa
      961 aattaaaggt agtagttact aattcgattt tagcagatat tactgaaaat atagcaaaag
     1021 ataaaattga tttacacagt atcgtaccta ttgggaaaga tccccacgaa tatgaacctt
     1081 tgcctgaaga tgttcaaaaa acttcaaaag cagatttgat tttttataac ggtgttaact
     1141 tggaaactgg aggaaatgct tggtttacaa aattagtaaa aaatgcgaac aaagaggaaa
     1201 acaaagacta ttttgcagca agtgatggca tagatgttat ttacttagag ggtcagagtg
     1261 agaaagggaa ggaagatccc catgcttggt taaatttaga aaacggtatt atttacgcta
     1321 aaaatattga aaaacagtta gcggaaaaag atcctgataa taaaaaattc tataaagaaa
     1381 atctagataa gtatattgaa aaattggatt ctctagacaa agaagctaaa tctaaatttg
     1441 cttcaattcc gaatgataaa aaaatgattg ttacaagtga aggatgcttt aaatatttct
     1501 cgaaagcgta taatgtgcct tctgcttaca tttgggaaat caacactgaa gaagaaggaa
     1561 caccagatca aataaaacac ttagttgaaa aattacgcac aacaaaagtt ccctccttat
     1621 tcgtagaaag cagtgtggac gatagaccaa tgaaaacagt atcaaaagat accaatattc
     1681 ctatctattc aacgattttt actgattcaa ttgcagaaaa aggacaagat ggtgatagtt
     1741 actatgcgat gatgaaatgg aacctggata aaattgctga aggcctttcg aaataatttg
     1801 gagggtaggt atggtacaaa ttaaaacgac tactatacta atttatttac tagcaattca
     1861 ggaattatca aaaagaaaaa agaaattaaa aaataatgat ttagcaaaag ttctaagtgt
     1921 tagtccagca tctgtaagtg agatgctggc taaacttaga tatgaggact atttagatat
     1981 aggatttcaa ttaactgata aagggaaaaa atttattgac gattacaaaa aaggttttaa
     2041 gtaaaagact ttatttttag ggaggataag aaaatggcta ttggagtgat tatgatagga
     2101 cttaccctaa tagctggata taattttttt aaatctttct cggattattt tagaaaaggt
     2161 gaatgattta gatgagtcta ttaattcttg taggattgct ttttgtatca gttattttgc
     2221 tctttctcat tagtttagct ctaaggaatg agttcagtaa tagacgttaa cgattgaaac
     2281 ttcaagtcct gtgtaagata atatagttaa ttcatcttat taggaggaag tacccataga
     2341 aaccagagat tatattacaa ctcaccaaaa attaatagaa agtggactaa gccattttga
     2401 aaaagaagga tttcagcaaa ctaagataag gcaactgtgc ttgaccgcag gcgtaactac
     2461 gggtgctttt tataaacatt ttacttctaa ggaagcgtta tttgaagaaa ttattcagcc
     2521 gcatattaat gcgcttatta atatgtataa tgaagagttt accaaatacc tcttaaactt
     2581 agaaaatata gatatagaga aaagttggag agagaacttc aatgaattag atccatttat
     2641 taattatatt tttgagaata aacgtatatt cgatttggtt ttattccaat cagctggaac
     2701 caaatatcaa gatattgttg aaaaaattac atcatttgtg acaaaaaaga cagtctgttg
     2761 tctagataag ttaaagacta tcggaatgat caatcaaaat ttagtcttta atgaagaaga
     2821 aatccacttc tacatttact cattctacgc tacattctat gatatattga agcatagcta
     2881 ttcaaaagaa aagactatgc tattaaccag aagattgtat caattttctg ttcctgggtg
     2941 gattgaatta ctgagttaat taaaaaaaag cttgcattga gaattgttct cagttatgct
     3001 ttttgataag atcgcactgt tatctgaata acggtgcatt tttgtcagct taagataaca
     3061 gtgcgatctt attttttgga ggtgaaagag tgtcaaaaat caatccgtta accttgatta
     3121 ctttaaatat ttttttccgg tcattatttt tttaggaaag ggaaatatat ttcaagtggg
     3181 gtgtttcatt attgctacag ttttagtatt gatgtttcgt aaaataaaga catgtattta
     3241 tttcatcttg atttattcag ttctgttttt agtaatgaaa attattgatg ctatcaagat
     3301 agagtttttt actatatttt ttgggacatc cttatatatt gtatttcgaa tgttgccggt
     3361 cgtaatgatc tcatggttgt tggttagtgt ctatactagc aatgaattat tatcctcttt
     3421 agaaaaaata catttaccga aaaaaataat gttaagtatt acagtagtga tcagattctt
     3481 tccgacttat cgttctgaaa taagaatgat taaagaatct ttaaaaatga gaaacattcg
     3541 cttgtctttt tttcagcctc tgcaatattt ggaatttctg ttagttcccg ttcttatacg
     3601 tgcaactatg attgctgaag aaatgaccgc taatgcaata acaaagggga tagaatctcc
     3661 tgtgaaaaga agttcttact ataaaacaaa catgagctta ttagactata tcatcctgtt
     3721 ttccgttact atttttttct taagtatttt gatttgaggt gaaagaattg tttgaattta
     3781 acaatgtttc tttttcatat aaggatgtta aggaacaagc gcttgttgac cttaattttt
     3841 caataaaaaa aggcagtctt acattgatta ctggttcttc tgggagtggg aaatccacac
     3901 tattaaagtt aatgaatgga cttattccaa gactttatga cggaaaattg gttggggaaa
     3961 ttttatttga aaataactcg ctacaatcct taacacaaga aagtatatca aaaaatattg
     4021 gctacgtaag tcaaaatcct agaggacaat tctttacaac aaatacaacg agtgagttag
     4081 tattttcgat ggaaaacttt ggatttacaa aagagcatat ggataaaaga atcaatgaat
     4141 tagctgaatt attagatctt tcaaatatat tagataaaaa cattttttcg ctatcaagtg
     4201 gtgaacggca gaaaatttct attggatgta gtttatcgct aaactctaaa ttaattatat
     4261 tggatgaacc gtcttcaaat ttggacttca aagcgactaa gaaacttgct gacttacttt
     4321 gtgatttaaa aaataaagga tttactattg ttatagctga acatcgtttt tactatttga
     4381 aagaattaat tgatcaagtt ctatttgtta aaaatagaac tgtaaaaact acaactattc
     4441 agttgttaaa aactgaaaac aataacgcat taaggaaatt tgacattttt aatagttcga
     4501 ttgaagttcc ctatatcgaa aaggtaagtg cagatgtatt aaaagttgaa gaaattactt
     4561 atgaaaatat tctaaaagac ataaattttg atgtcaaagt tggagatgtt attggtttgg
     4621 tagggaaaaa cggtgtgggg aaaacaacct tactaagaat actcatgaag attattcgcc
     4681 ctaccaaagg aaagataatc gaaaataaaa aaaatttgtc atcgccgttt ttagtaatgc
     4741 aagaaatgga ttaccaattt ttcacagaat cagtgaggag cgagttagcc ctggggaatg
     4801 aaatagttag taaagatcag caagaaaaaa ttttaaaaaa aatggaactt tataaaatga
     4861 aagatcaatt accgtttgat ttatccggtg gagaaaaaca aagattattg gtttctatag
     4921 cttcattgtc aaaaactaat ttatttctat ttgatgaacc tacaagtggg ttggattata
     4981 tcaatatgga aaggattgct gaccttatta aagacttaaa agaaaagggt gcagtagtta
     5041 tagccactca tgatccggaa tttctttata aaacatgcaa tagaattatt tatttaaaaa
     5101 atggtggaat aaaaaaagat ataaaactta gagtagaaga ttcaactttg atagaacaga
     5161 tttttaatga cataacgaaa tagaattgag gagaatatat atgaaaacaa aagattatat
     5221 ttttattggt ttagctacag ttatttccct agtaatttac tttttttcaa taatggttag
     5281 tagtattggt ggggcgtttg gtcacagcat atccccaggg atttttggat tattatctgg
     5341 aatcatattt gtttatatta gctataacta ccctagaaaa ggaattttta ctatttacac
     5401 aattgtttta ttgttatttt ttacgttaat gggcggggcg tacttacctt ggtttatcag
     5461 ttcgattagt atggcgatct tagctgatat tattctatct gtatttggat atgatcgagc
     5521 aattcctcaa gttgtgtctt gggttctaat gcaactaggc agtgctgccg gacagtggat
     5581 tcccatatgg ttctttacag atcgttttcg tcaagactgg atagatagag gacaatctgc
     5641 tgcaacaatg gatgcaatga tccactacgc ggtgggtata tggggaatta tttcagtgtt
     5701 agttgtagca agtttatcta tgattggtgt attgattgga agaaaagtct taaaaaaata
     5761 caaaaaatag aacgtagttt accttctatc tgtttgtaca tctctaattt acgctattac
     5821 ggaaagcatt aacagttgta aacgaataag agaagaaatt gaatgcgggg gaggaaaaaa
     5881 tgaaagtata caaaaaatta tttagttatg tccctaaaat gaaatactac ggatggttag
     5941 ccactttatt ttctgatttt tctgtcgtat taacagtcta tggatattac agtatttaca
     6001 aatttcttca gtctctaatt attgtaggag atgaatattt agctaagagt tatgcggttc
     6061 aaactgttgc ttggttaact ttaggagctt tattttatat tttttctggc ttattttctc
     6121 atatccttgg gtttcgctta gagactaatt tgagaaaaaa gggaattagc ggtttaacag
     6181 aagcaagttt tcgttttttt gatttaaatt cttcgggata tattcgaaag acaattgatg
     6241 acaacgcggc taaaacacat atggcaattg ctcacttgat tccagatagt gctcaagcca
     6301 tagtaacacc tgttttatca gttgccttag gctttttcat taactttaaa attggattgg
     6361 ttctaatcgc catgttagta attggtgtat tcttgttaaa gaaaatgaca gagaatacaa
     6421 attttattca aaaatatcaa gaatcgttag atgtgttaag ctctgaaacg gtagaatata
     6481 tccgcggaat tcaagttata aagatatttg gtgctaaagt aacatcattt aaagccttga
     6541 ataaagcaat taacgattat gctaagtttg catataagta ttctttgagt gggaaaacac
     6601 cttttgttct ttttcaatgg ctattttttg gcatagtttg cattttgata gttcctataa
     6661 ccttttttat aacttctctt accactccca agatcttagc tgttgacttg ttgatgttgt
     6721 tttttttaag tggaattatt tttgtttctt tcatgagaat aatgtatgta agtatgcact
     6781 tgtttgaagc aagatatgca gtcgaaacac tagactccct ttatttagaa atgaagcaag
     6841 accaactaaa atatgggaac gagacacaga ttaaaaattg tgacattgca tttgaaaatg
     6901 tcagcttttc atacaaagaa gagtgtgttt tagaaaattt caacttagtt ttagaacaaa
     6961 aaagaattta tgcattagta ggaaaatcag gaagcggaaa gagtacgata gctaaactaa
     7021 tttcaggttt ctacaatgtg gataagggac agattaaaat tggtggtaag cctttaaatc
     7081 actattcaaa agacacaatt attaacacaa ttgcttttgt ctttcaagat acgaaactat
     7141 tcaatcagag tatttacgat aacgtttcta tagcaaatcc tcaagcgcca gcaagtaaag
     7201 tatttgacgc gctaagatta gccggttgcg aatcgatttt agaaaaattt cccgaaagag
     7261 agcatacctt aattggtagt aaaggagttt atctgtcagg aggagaaaaa caacgtatag
     7321 ctattgccag agcaatttta aaagatgcaa agattgttat tatggatgaa gccagtgcat
     7381 ctattgatcc agataatgag tatgaactac aaaaggcttt tcaatatttg atgaaagaaa
     7441 aaacagttat tatgatagct catcgattat ccagcattaa atctgtagat gaaattcttg
     7501 tcttgtcaga aggaaaaata gtagaacgtg gaaatcataa tgaattaatg gctaaacatc
     7561 gagtgtataa acaattggtc actaattatg agaatgcaaa tgattggagg cttgacaatg
     7621 aaaaattttt ataaaaaaaa atttgcttta actgatcagg gcgcagaagc tttaactaaa
     7681 gcttctattt ctagtttttt tgtatactgc attaatatgg taccagcatt cattataatg
     7741 atgctgatag acgaattagt tttagaaaat gcaaagcccc gttggcttta ttttgcagta
     7801 tcgtttgtta ctttgctttt catgtattgg ttgttagata gggagtatga aaacttatat
     7861 aatagtactt ataaagaaag tgcgcattta agagtgcaaa ttgcagacga tttgtcaaat
     7921 ttaccattat cctatttttc aaaacataat ttatcagatt tatctcaaac tatcatgtct
     7981 gacgttgaag gtattgagca tgcgatgagt catgcaatac ctaaagccgg cggtatggct
     8041 ctgtttttcc cttttatttc agtgatgctt ttggttggta atgtcaaaat gggattagct
     8101 gttattttgc caacgttatt tagttttgtc ttaatcttgt tatcaaagaa atcccaaacg
     8161 aaagccaata ctaaatatta cgatactttg agagaaaact cggaagaatt tcaagaaact
     8221 attgaattgc agcaagagat taatagcttt aatctatcta aaaaagttca agacagactt
     8281 ttcaaaaaaa tggaagagag tgaaaggatt catttaaagg tagaattaag tactttttca
     8341 gtcatggcct tatcctctat tttctcatat gttagtttag cagtagtcat tctagtaggt
     8401 gttcacttac tgttaacggg tgaagtgact atactctacg tcgttggtta cttactagcc
     8461 gcaataaaaa taaaggattc cttcgattct atgaaagaag cagtgcttga aatattttat
     8521 ttagctccta aaatacagcg aattagagct atgaaggaaa ccagtatcca agagggatca
     8581 gatagtcctc tgaaatcttt tgacattgag ttgcgagatg tctctttctc atatgataac
     8641 aataccccaa ttttagatca tatctctttt acggctaaac aaggagaagt gactgcgtta
     8701 gtaggtgcta gtggttccgg gaaaactagt atcttgaaat tagtgtctag actgtatgat
     8761 tatgatgaag gctgtatttt aattgatggg tatgatatta aacgtgtatc tccagcttct
     8821 ttgtttagca aaatcgctat tgtttttcaa gaggtaactt tgtttaatac aagtattttg
     8881 gaaaatatac gtattggaaa tagtcaagcg tcagatgagg aagtgaaaaa agcagctcgt
     8941 ttagctaact gcgaagactt tattgaaaaa ctacctgacg gttatcatac attggtcgga
     9001 gaaaacggaa gttcactttc tggaggagag cgacaacgcc tatccatagc acgggctttt
     9061 ttgaaaaatg cgccaatttt aattttagat gaaattactg ccagtttaga tgcggaaaat
     9121 gaaaaacgta ttcaggaaag tttaaatcgt ttaatacaag ataagacagt actaattata
     9181 tcgcatcgct tgaagtctat tgaaaaggta aataaaattg tagtgatgga tcaaggaaaa
     9241 ctagttgatc aaggtactca taatgagttg tatcgaaggt cagaaatata caaaaatctc
     9301 ataaagaaaa ctaaactatc tgagaaattc gtctatgaaa aagaagctca atcacgatga
     9361 tgaaataggc tttaaattaa cctacaattt ttgggatata gttataattc tttttcaaaa
     9421 agaataattt tattaaacag catctaattt tgaatacacg aaagaatcag tatgattgaa
     9481 ttagttcact taatgtctat tcttataata taaggaataa tcaaagtttt aaaaaattgg
     9541 cgataaacca gttaaacata aaagattgaa taaaaagtta tagtttcttt catattgccg
     9601 ttttaagtag aggaaaagct acttaaaacg gtatttgtgt ttgattggac taataaaagt
     9661 gaattcttat ttttcagagc ctaaactgca tattctttta aatgatttga ttatctctat
     9721 gtaccgataa attcgttttc aaatagttat ctattcatat gagttttatt tcatgttatt
     9781 tattgttgac aagagcaact cttgttggta aagtatcagt gtcaaaacgt aacgattacg
     9841 atttgaggtg tctaaatcaa aataaaagga gtataaaggt atatggcaaa aaagtcgaaa
     9901 attgctaaag caaagaaaca aatggcgatg attgaaaagt atgcagataa acgtcaggaa
     9961 ttaaaagccg caggagatcg caccgctctc gctaaattgc caagagattc aaatccgaat
    10021 cgtctgaggc ttcgtgatca gacggatggt cgtccaagag ggtatatgcg aaagttcggt
    10081 atgtcccgta ttaagtttag agaacttgcc catcaagggt tgattcctgg agtaaaaaaa
    10141 gcaagttggt aaaaggagga aatatcatgg cagtaccagc aagaaaaaca tctaaggcga
    10201 agaaacggtt aagaagaact catcaaactg tagtaaaacc agaaatttca tttgacgaag
    10261 cgaatggtga ttatagacgt agccatcatg tatctttaaa agggtactat aatggaaaga
    10321 aagtaattaa aggagcttca aaatagttta atatataact tttaggaggg aatcaaaatg
    10381 gaaattattt acccaccttt agttgaagaa ggattaaagt attatcttga aacgacccag
    10441 caatcgctag ataaatgcac tttttatcgt tcgatggtag agagaggaat tattactgaa
    10501 acgggtttac cgacccaaca ggcaattgaa aatggattag tcaaagatta ctatgaggac
    10561 caaggcttat catttgatga ttttttaaga atctatccaa tttttgaaga gtatgacgag
    10621 gagttatttc aatgtatcga tggttattgg gagatacctg ttgatatgaa agaaaattta
    10681 gtttcacaat tggaatctgg cgagttaact tttgaagatg cacaacaaat tcaagcatat
    10741 cttgaagatc gataagtatt gaaggaggaa gatttatgcg tcaaaatatt attttggaat
    10801 gtgtcgaaac tggagaacgt ctgtatctca ccagcaaaaa taaacggaat aaccctgaac
    10861 ggttagaatt aaaaaagtat tcgccaaaat tgcgcagacg ggcaattttt aaagaagtga
    10921 aatagctaag tggtaaaaag gtgacaaaat gggcatacca gttacaatcg tttctgggtt
    10981 tttaggggct ggaaaaacaa cgctaatcaa tcaagccttg caagtctcac cctaccccag
    11041 ggaagaaatt attataattg aaaatgagtt tggtgaagtt gggattgatc acaaattatt
    11101 agttcatagc gaggaacggg tgttacaact aaataatgga tgtatgtgtt gcagtcttcg
    11161 cagtgattta ttagcaatat tgatttcttt actggaaaca atagaagaac atcaacaacc
    11221 aatttcacaa atcatcattg aaactacagg tatagcagat ccccaaccaa tcattcaaac
    11281 acttttaaca gcgcctcaac taagaggaag agtatatatc gatagtttat tgactgttat
    11341 tgatagtgac agttttgaac ttattgaaag agaaccacaa gcccttaagc aacttgtcat
    11401 ggcagatcgc atttttgtgt ctagaaaaca aaacttgaat ttatctgcac taaaaaaatt
    11461 acagagagaa atcaaaagta ttaacccttt atccgatatt cgaatgttca cacatagtga
    11521 aacgattcaa aaaaaggatt tttataattt gaaaaaattt aatcatccct tagtttttga
    11581 aagtgattca tcagaaaatc actataatgg caaatactat catcaacacc atcaagtaca
    11641 tgagtttaaa tcaattctct taacttcaga tcaagacata aaaaaagatt ttttactcca
    11701 atggattgac tggctgattt taaccaacca agggagcctg tatcgtttta aaggattgat
    11761 tgctttacaa gagcaggatt ttatagttgc catgcaagag gtaaacgaac aggttaattt
    11821 tcaatacacc actcgacaaa aagaccaaac cactattatt ctaatcggaa aaatgttgga
    11881 tgaagaaagg atcaaacaga gttttgataa attactggcg gaaagcaaat aatgataagt
    11941 agtgattggg ggtaatttct aatggagaaa acggatatat ctagtgcata tcgacgactt
    12001 aaaagcccga atattaaaac tagaaaaagg gcattaaaaa ttatcaaaga acataaacga
    12061 aataaaatga agaaattagc ataattaagg aaggaaaaag aatgaagaaa atcagtgtag
    12121 gacttattgg gatagcagct ctaggattat tgggagcttg ctccagcact aatgatgcaa
    12181 aagtatcgaa tgataaagat ggaaaattag aaattgtaac aacattctat ccaatgtatg
    12241 atttcaccaa aaacatcgtc ggcgatgaag cgaacgtgga tttaatggtt ccagcgggat
    12301 cagaacctca tgactatgag ccctcagcta aggatatggc aaaagctcat gatgctgatg
    12361 tttttgtata tcataacgaa aacatggaat catgggtacc aaaagctaaa gaaagttgga
    12421 agaaagctgg gcctaatgta gtagaaggaa caaaagacat gattttattg ccaggtagtg
    12481 aagaagaaga tcatgatcac ggagaagaag atcaccatca tgaactagat cctcatacgt
    12541 gggtttcacc caaaatggca attaaggaag tttcaaatat caaggatcag ttagttaaat
    12601 tgtatccgaa aaaagcaaaa gtatttgaga caaatgctga aaagtatttg actaaactga
    12661 aacggttgga tgctgactat accactagtc ttaaagaagc gaaacaaaaa agttttgtga
    12721 cgcaacacgc agcctttgga tatttagctt tggattatgg attgaaacaa gttcctattg
    12781 ctggactaag tcctgaagaa gagccatctt ctggtcgatt agctgaatta aaagagtatg
    12841 ttaaaaaaaa taagatcaat tatatttact ttgaaaagaa tgctaatgat aaaattgcaa
    12901 aaactttggc caacgaagct gggataaaat tggaagtact gaatcctctt gaaagtctta
    12961 caaaagaaca aatggataat ggtgaagatt atgtttcagt aatggaagac aatctaaaag
    13021 cgttagaaaa aacaactatg gttgctggtg aagaggtagt tccagaaaaa gaagcgaagg
    13081 atgaaaagac agttgctaat gggtacttta aagatgccga tgtgaaggat cgcgaattga
    13141 gtgattatac aggcgaatgg caatctgttt atccgttgtt aaaagatgga attttggatg
    13201 aagttttcga ttacaaagca aaaatcaata aagacatgac agctgccgag tacaaagatt
    13261 attatactac tggctataag acagatattg atactatcaa cattaaagac aacaccattg
    13321 attttgtagt caacggtgaa catcatcaat acacatacaa atatgttgga tacaaaattt
    13381 tgaattatga aaaaggaaac cgtggtgttc gttttaattt tgaaactgat gatgcaggtg
    13441 ctggtcgttt taaatatatt caatttagtg atcatggaat tgcaccaagt aaggcagagc
    13501 atttccatat tttctttggt ggagaaagtc aagaaaaact ctataatgaa ttgcataatt
    13561 ggcctacttt ctatccagct tcattgtcta aacatgaaat tgctcaagaa atgatggctc
    13621 attaaaattc aatttttgga ggaaatacat ggtaagaaaa gtattattgt ctatggattc
    13681 caagaatatt gatgcttatc ggcgttatcg atttgcaaag caaatgagat taaatgggag
    13741 tacattagct gatattgctg caactttaca tgttagtatt gacacagttc atagagtatt
    13801 aaaacgggat cctgattgtt gttttatcaa ggtcaatact ggaagaagta gacgtttagc
    13861 aaaacggcat aatagcttgg ccaattaatt gataatacca gagtagatca tttttccctt
    13921 atttggattt gatctgcttt ttattatgtc ttgaattgtc aaatcaagcg caacacttta
    13981 tcaaagaaga cttcataagg tgttctccaa tctaaacact ttctaggtct gttattcagt
    14041 ttttcaatca tctgatttat cgttgagtta tctaccgtag ctatctcttt cgattttggc
    14101 aagtattctc gaatgagtct attcgtattt taatttgttc attgttgcca agggcatgag
    14161 gatctggaaa ataaaagggc atattattca atgcttctgt aactgcgaaa tgattggaga
    14221 attcttttcc tctatctgga gtgatcgttt tgaccgcctc atttggaata ctgcttaaaa
    14281 gttcaatcat tttctcgctc acataagcgg ctttctttct ggggaccttc tttcctgcta
    14341 aaaggaagca tgattttctg tctgtcaaag tcactaaaca agtaccacca gttttgccag
    14401 ctacaatatc ggctttccaa tgaccaaaat cacttctatc atctgcggat tttggacggc
    14461 catggatcga atgagtaagg caaatctttc cacgagactc gacatgattt tttgtatgtc
    14521 ttgtttttcc tcgatggtgc aatgaacgga tcaggccttt attgccgtgt gagaggggtt
    14581 ctgtatcgaa aagatcattg caaattgcac gttagatcgt gataaaacta attgaaaagt
    14641 ccatatgttc atgcttcaaa cgattcgaga tttcctctgg cgaccactga aaatcgacaa
    14701 ataaatgacg aacaattgac caaactcacg gatcatttag aatgtgataa cgtccgcatt
    14761 tttttcttcg ataagcataa tttttttccg ctttggaagg tgaatagttt ttttcttgtt
    14821 tcttctcagt tcatgtaaaa tagtaaacgg gctatgctga atgtcgttgc caattatact
    14881 aatagaaaat ccttcttcgt gaagcagaaa gattctttct cgttcgagta tagtaagatg
    14941 acgatactgg ctcataatta ttttccttct aggagtgttc tcgacaaact tatactagtt
    15001 ggatatcgat tatgactcat ttttatgtgt tgcacttaaa gtgtaaattc aaggtataga
    15061 aagaggttcc ctatgaaaaa aatacctatt acaatcttaa ctggctatct tggttcagga
    15121 aaaacgatac ttctaaatca tattctgtac ggtgatcacg gaaaggaaat tgctgtcatt
    15181 gtaaatgaca taggggaagt aaatgttgat ggggtattag tcgacaagaa aggttttaaa
    15241 agaactggag aaaaacttgt ttcgatgccg aatggatgca tttgttgtac attacgcgaa
    15301 gatttgattg ttgaactaga tcaattagtg caattttctg acttgaatca aattgttatt
    15361 gaagcttcag gaatcagcaa accaattcca attattcaag caattatatt agctaaaaac
    15421 cctttagaca ttgatttgac ccaacgatta gagattggtg ccattattat agtagtggat
    15481 gtaaaacgtt tttgggataa tttcgaaacg ggtgaaaaga ttcaggaaag aaaagctgaa
    15541 ggtaatgtag ttgaagaaga acaggatatt cgtggcttgt taattgatca attcgagtgt
    15601 tgtaacatat tacttttaaa taatagtgac ttagtgtcaa ccaagacgat ttacaaaatt
    15661 aacggtctaa ttgctaagtt acagtccaat gccaaaataa ttaggacaat taaaggtgaa
    15721 gtagacttat cgaaaattct aaatacaaat ctttttaata tagatgagac ttcctattca
    15781 gtgggctggt tcaaagagtt agagcttggc tatcaaaatc atattcctga aacagaagaa
    15841 tatggtatct caagttttat ctatcgaaat cggttactcc ttgacgcaca aaaatttgcc
    15901 catcttacgg ataaaaattt tcctggcaat attacaagag caaaagggtt tctttggttt
    15961 gcccaacata gtgatttttc gacgatcttt gaaacatcgg gtagctataa aagtattgaa
    16021 tcattaaatt attgggtagc tagtttacct aaaattgagt gtcaaatgat tatacaaaaa
    16081 aatcccgaat tgaaggaagc ctggcatccg ttgtttggtg aacgcattaa taaactagtt
    16141 tttattggta tgaagatgga tcaacaatgt attaaggaac aacttgaggg ttgtttaact
    16201 gattctctta atgcagataa tttccgaaaa atttcaccat ttccatggaa aaagtctaat
    16261 atgtttagcc agatatcgtt aatgaaattt ttaagaaaag ctggtgtcaa gataggcgat
    16321 gtcataatta ttggcatttt gattattacc tcttttattc ccttatttgt attctctata
    16381 gaaaaggaga atgaaacaac tgaagatgct atcaaatatg ccatcgttcg aattgatggc
    16441 aaggaaatgg atcgcttcga tttggataag atcaatcata aactcgtgaa ttatcatcct
    16501 gcgaagggac aatataatat tgttgagatt aaagatggaa gaattcgagt taaagaagat
    16561 aatagtcctg atcaaatcgc ggttagaact ggatggatct caaaacccgg tcaaacgagt
    16621 atttgtttac cccataagtt agttattagt attgagaaaa aagaaagcac agattactac
    16681 atttactaat ctggaaatag atgaggaggt ttttaataag aaaaagatat tattattaat
    16741 aatagcaggg gctttattaa gtgtgttaag cgcttgtgga caagaaaaag aagcggtgac
    16801 aacaggcaca agtatcttta acgggacctg caatggttta gttaacagtc ggttagatta
    16861 cttattttgg ctcttcgtca atgagtgttg gtgaagaaat tcaatagaat aatcgagata
    16921 ctcacacggc tagacagcta tcttgtctag ccgtgttgtt gttctggctt tagtcagttg
    16981 ggtagtattc ttagttttct taaaatattt tcctcgatat aaaaagattc gttctcggta
    17041 gttttgaaag tttctatagc cataggcaat tcgttttagt actttgatat ggttattcaa
    17101 acattctata gggccgttgg aatagggaac gcgcaacgct cgtttgattt ctgtttggta
    17161 tttcttgaag gtcgtgaaca ctggttggta gtgctctggc aactccttgt agtcttcttt
    17221 taggagcgcg acgaattcag gaacatcttg tcttctgata acggaaagaa aatcctggta
    17281 gacttcgtag cctcgcttta aggaatcatc ataagataat agccgatcga ctatctctgc
    17341 ttctgtcaga tgatctcgaa atgacggacg ccagtagcga tgctgacctt tcaattccca
    17401 cgcattcttt tgaagtagtt tccagtattt ctttaagtgc ttcgaccgac gatccccttt
    17461 tttaaaggtc ttcattactt gaattcggtg gttggtaaaa gcccgaccaa tgtgttggct
    17521 aatatgaaag cgatcggcga cgattcgggc attcggaaaa cactctttca ccaatgtgcg
    17581 atagggtgta tagaaatctg aaaccactag acgcacttgt tcacggactt ttatagggta
    17641 gcgcaagaaa tagtcgcgta aaggattgag ttgccgattt tccacaatat caatcagttg
    17701 atgggtcttg ccgtccatca tgacaaagct catggctccc gagacatttt tcactgattt
    17761 gaattcatcg aaacacacca cttctggtaa cagctggctc aaagaaatgg ttttaggccg
    17821 aaggctgcga agtattcgaa tgacagtggt cggagaaatg tgcttcatac gtgcgatcaa
    17881 agacatagaa agaggttcgc ttaatagctc aagaatggct tgtttgactc tgcgagcaat
    17941 ggagcagcga cgatcactaa ctgaatcttc tgctaaaaaa gtctttccac agtgtttaca
    18001 tttgaagcgc tgtttgttaa tccgcagaat ggtcttgtag ttactgacat cattcaataa
    18061 gatggatact tttttccagc cctatttaat gatcgtttgt tcattttgat agtggcgatg
    18121 aaagcattcc tccggttgat aggtcaatgt gccatcaaaa gcaaaacatg tttcgtcatt
    18181 gatgcgctct ttgcgaaagg catcctcatg aaaggtaaga tttaggtcta gaatatctag
    18241 taactctttg gtaaactctg aataggacat cttgaaacac tactttgaat ggtttttgtc
    18301 gactttattc taaaggattt taaggtgtct gtttgcgttt attagaaaaa agaaaaagta
    18361 ttggcaacag aaggcgtcac caacactaga tattatagat cccttatttt cttcgcttca
    18421 aattgtcaag gagtcatcat aaattttgta tggattcttt tgtttgggta gtagtcttct
    18481 aaataatctt ggattaacac cttcatctct attttacttt tatatttgtt ggagtcgatt
    18541 aattctcatt tgattgatcg atgaaacgct tcaattactg cattgtcaac aggagtccca
    18601 gtttggctca ctgaatgtgt gatgtggtgg tcgttcaaca gctcttgata aataaaagac
    18661 cgatgctggc tacctctatc ggaatgaatt accgtaggca attctcctta ataaatttgt
    18721 aatggacgga cgacaatctc tttttttatg tgtgaatcta ccatatagta acgtagaata
    18781 cgagttgcta agtcaatata ggtggacaaa tagaggcgac cgtcattaca tggaatgtaa
    18841 gtaatatcca tcacccaaac agcatcaatt tggttctgtt caaattatcg attcaacatt
    18901 tttttaccat ttctttgatt gttttttctc taccatgaga agatttgcgt cgatgaaatc
    18961 ctcttgtgca taaattcatt tcacgcataa gaacagctac aacacgttta ttgatttcga
    19021 ttccttcatc gtaaagtttt tgagtgatcc ctggagatcc gtatcgatct ttgtgttcgt
    19081 agaacactcg tcttcctctt ttagtcgttt attttcctgt tcaagaatgt agaaatctgc
    19141 tttatcaggt aatctttttc cttgtccagc aaaagcattt ttcccgtatc gacgatattc
    19201 tgaaacccat cgggaaattg ttggacgaga gatattgtat tcttcagcaa ttttcttggt
    19261 agttactttt ttctcaagga tatcctgtga aatctttagt ttaaatttac gatcatatgt
    19321 ttttctcaat agagttcatt ccttccggta acgtaactga tagtcaagaa aagtgtatca
    19381 tagcccaact tagtatcagg gtttgtcaac taaactgtgg aagttgatag ataagagttt
    19441 ttaacaacca aaattctctt gactattttt gaaatcagac aaattttgat tggacacata
    19501 gttgaataaa tctaccgtcg ttacggaagg taaatcgcat gcttttcaat tctagaggag
    19561 aagtcctcgt tgaagtacca tagcccagtt ctggattcga cctcctgccc acttcatacg
    19621 taaataaagt aattttagga gtgagactgt gacaaaagtt atttttaagc taaaaacgaa
    19681 ttaaaaaacg ttgataatta aaatcattcg ttttagattc tatgaatcat tatagaacgc
    19741 tgtaaaatcg atactttata attataaaga agatagtttc aaatttattg ttcgaaattt
    19801 gaaactatct ttttacttat gtcacagact cccttagttg agttattctt taatttcgaa
    19861 tttcgagata gctagatata ttgcaagcat acattcttga taacaatctt gatcatattt
    19921 tccagttctc caggattgct tatgaatcaa agagctaaat cttttgagaa ttgcctcaac
    19981 agcttcttca tttccagcct ttgctaaaat gaaatcttct tttaaagaat tcataaatct
    20041 accttcttcc catggactta taatctattt ctttgggaag gaggagaacg agcaaagaag
    20101 catacaaaat tagttattat gcagatatta aaccagcatt ttttgaattt ttttgtaaag
    20161 tcgatgtttt aaatttgtcg caccctgtct tgtaatcccc agaacctttc caatttcttt
    20221 atcagtttta tcaaagataa atttttcgat aagaaaaatt tgttcaggtt ctttcaacaa
    20281 aggaaggatt tttgctaatt ttatatcttc aacaaggaga gtcacattta aaacattaat
    20341 cggttgttta aattttatag tatctttagt aaacaaatat ggtgggagtt gatcaagttg
    20401 ttcatgtttt tgaatttctt cttgtttttt ataataagta ttagcggtgt tcaaaatgac
    20461 cttttcaaag aatcgaatca actgggcatt tacgcgttcg tcgttatctg acatattgca
    20521 cacctcctcc attaagattt aaagggaaaa gaggcaaaaa acacgaaaag aagctaatgc
    20581 aattatgctg cgctgcgaat aacttctata agctcacatg cattgatagg actgctgatg
    20641 tttattttca aaaatgtttt tttagttgat aatggatagt tatctttata cttagaaaag
    20701 aaaattcata tatcttctta aatatcaaac atgtccttat ggctaagaaa atgtcttgag
    20761 ctttttacgt ataataaatc ttttctaaaa cctccttttg gataatattc ttattcgtgt
    20821 atagattgta ttttttattt cttccccctt cataattaac aactagaaaa gagttcgaat
    20881 agacacgtat ttgaacgaaa atttttattg gattcccaaa ttggaatatt tagaaacgaa
    20941 aaattcctat tatctgtata gtgcttagat aataacggat cataataatt attgtctttg
    21001 aactagatat atgtaaatag tattcatcat gatgaaaaat gatgagttct cggtgataaa
    21061 atgtactttt tacggtggaa tatacatgaa agcgataagt ggatatttta taatgaagta
    21121 agttagctta ttttgacaga ggaatagtat tttagataac gtataaaata ctatttaatg
    21181 atgtagaaag gaaagagaga aacaaaagtg ttttcagata aagaagtctt attaaagtct
    21241 cttcatgttt gtttaaagtt acctatcgtg gtttttaatt ccgaattcag tattataaaa
    21301 gagtatcgct cagatagaac tacttatttt ttttatgatt ataaaaagtt actaactgat
    21361 aatattaaaa aaactaaaga tttccatttc tttactggtg attttaatga gatgtttctt
    21421 ctatacatgt ttaaaaccag atattactta tttggtccat ttagagcaaa taatattgat
    21481 aaagtttttt ttaaactaaa aatgaacaat ttgaatgttg caatggctga tagagaacga
    21541 ctctataatt cattgcaaaa tttgactttg tattctttag gagacattcg agatattctg
    21601 attttagttc attatttttt tactggaaaa atagaagatc tattccatga accgttaatt
    21661 gaatatacag aaaatctaag taaaactatc gagcaaatca aaatagataa tctgttatca
    21721 caaaattacg atccagaaat atatctgttt ctttatgaaa ataaaatact ggaatatgtt
    21781 aaaaatggag atattcgaaa tttagaaaac atggttttta atctgagtaa tggaataatt
    21841 ccaagtgtta gtggagatac gattcggtct gaaaaaaatt attctatcat tgtttttgaa
    21901 aagttagcac aaacgtctat aacattagga atggatataa tagaagcgta tcaaagtaga
    21961 gatgctttga tacaagaaaa cgaattagct gtatcgttac ctgaggtctt aaaagtgagg
    22021 gattctggga ttgtttatta tactaaggaa atcggaaaaa ctaagataga gcatctttct
    22081 cccttaattt cttctgtcgt tcaattcatc ggcttaaata tctataaaag aattactgta
    22141 aaggaaatag ctaattattt ttctgtaagt gaaactaaat taagagaaag ctttaagaat
    22201 gaaatgcata ttacgattta taattatatc tctaagcgaa aaatttctac ggctaaaata
    22261 atgttgaaat caaaccatac tatcagtgaa gtttctttag gtttaggatt ttcagattct
    22321 tcacactttt cgagagtatt caaaaagtac gcaggtgtat ctcctaagca atatcaatta
    22381 ggtttagtgg acaatttcaa caacattagc tgagaggttt tattttatta tgagactata
    22441 tcatttacgt agtttggagg agttgaggaa attggatttt aacaaaaaat ttttttggga
    22501 aatttctgat ttgagttgtt tcgtagaatc tgagcgtcta agtaatggta ataatagtgt
    22561 gttaaatgaa tatgacaaag tagtaattaa taaagtaaaa agtttatgtg aagaagctag
    22621 agaatctatc agtcatatta atggtagcaa ttttaaacaa acattattta atctgattaa
    22681 gctagatgct aaaatatcaa gttatttatt ctttttgata catgatgaat ttatggatta
    22741 tcaaaaattg gatcagttaa ttgaaagaga aagctgggaa gattattacg tgggtctaac
    22801 tttttcagaa aagttaaaca actacaagtt aatagattat aagtatttga gtgaaagcaa
    22861 ttaattattc atgtagagta ctagacactt taaatatgga caattcaatt ataaagaaaa
    22921 agaatcaata atttaatgag gctgtgacaa atgtcatttt ttgtttcgct aaaaacgagt
    22981 gaaaaaatgt tgataactcc aatcattcgt ttaagattct aggaatcatt cagaaatgct
    23041 gtgaaaccga tactttataa ttataaagaa ggtgatttca aattccgaag aaggaatttg
    23101 aagtcacctt tttacttatg tcacagtctc attcagtaat gcgggataag gctccttatt
    23161 ccgttatttg aatactctga agtttaatct aagaaagggt aatattttga aaacatgctt
    23221 catcgcatag aaatgaactt aatttcagaa agaatacata catatctttt tatatgtttt
    23281 cagctgctga atggttaaaa agcacaaata tccgaaaaaa acatgaagaa atgtactttt
    23341 tttgttgtaa tgttcatgaa attctctaag taaattagtt aacataaggt tagtaagatt
    23401 cctattctgt gaataatacg tatcagattt atcttttatt cttactagga aagtaattat
    23461 taagggagtt gatttgaata atggttagca agaataataa gagagtattt ctagaaaaaa
    23521 caaagaaacg agtattgaag tacagtatca aaaaattaag tgttggggtt gcatctgttt
    23581 tgattggtgt tggtcttgtc ttgggaacaa ctgaactagt taaagcacaa gatgaaattt
    23641 ctccaagcag cccacttgaa acagcgataa gctccgtaca agtaggtgac aaagtagctt
    23701 cggggaatac ttttcaggag aatcctggtt atacgaaaaa ttataacttt tcggatttac
    23761 aatttagtcc tcaagaacta actggagaca cactaaaagg caatacaatt ggatttgaag
    23821 tttacggaaa acataatatt gcagcatcaa ctaaaaactg ggaaatccgt cttcaattag
    23881 atgaacgatt agctaaatat gtagaaaaaa ttcaggtcga tccaaagaaa ggaattggat
    23941 cttctagacg gacctttgta agaattaatg attcgctggg tagacctaca aatatttgga
    24001 aggtcaatta tattcgtgca agtgatggat tatttgctgg ggcagaaaca accgatacgc
    24061 aaaccgctcc taatggggta attacgtttg aaaagagcct agatgaaatt tttaaagaga
    24121 taggcataga caatctcaag accgatcgtt taatgtatcg aatctacttg gtaagtcatc
    24181 aagacgatga taaaattgta ccgggtattg atagtacggg ctacttttta acagattcag
    24241 atgatttcta taatagctta gatgtatctg aaaataatcc tgaccagttt aaacatggat
    24301 cagtaagtgc aaaatatgag aaacctaata ctcaaacaaa agatggttca ggatccacag
    24361 gtgctaatgg agctataatc ttagatcata agttaacgaa aaattataat ttctcatatt
    24421 catcttccgc aaagggcacg ccttggtatg ctaattacaa aattgatgaa cgattagttc
    24481 catatgtagc gggtatacag atgcacatgg ttcaggctga caaagtaaca tatgatgttt
    24541 cgtttgaatc cggaacaaaa gtagctgatt tagcaatcga gcgacgggaa ggtcatgaaa
    24601 attatggcat aggttcaata actaataatg atttaactaa acttatcgat tttgctaatg
    24661 caagtccacg tccagtcgtt attcgatatg ttttacaatt gactaagcca ttagatgaaa
    24721 tcttagaaga tatgaaagca acagcacaag ttgaagaaaa taaaccattt ggtgaagatt
    24781 tcatctttga ttcttggttg tcggatacga ataaaaaatt aatccagaac acttatggaa
    24841 caggttatta ttatttgcaa gatattgatg gtgatggaaa ccctgacgat aaagaagaga
    24901 gcggagacac gaatccatat atcgggaaac ctgaattaga agaagtatat gatgttgaca
    24961 caacagttaa ggggaaagta ttcatccacg agttagcggg aacaggtcac aaagcccaac
    25021 ttgttgataa agaaggtact gtattagcag aaaaaactat cgctccaaat gaaaaagatg
    25081 gggctccaat ttcagatact gtagaatttg aatttacggg tgtagattca agtaaattaa
    25141 tcgcgaaaga tgaattaaaa atccaaatcg tttctccagg ttttgataaa ccagaagaag
    25201 gttcaaccgt tattaaggaa tcaccaaaag cggttgataa acaaaccgtg gtagttggat
    25261 ttaaaccaga tgctaaagaa tcaattcgga ataataaaaa cttacctgaa gatgcagagt
    25321 attcatggaa aacagagcct gatacttcta acgttactga tagtacgaaa ggtattgtaa
    25381 ctgttaagat cggaaatcga actttcgacg tggatgtaga gtttgctgta aaagcttctc
    25441 aagctatgga aaatgatgca acatacgtac ctataacaac aactccagaa acgacagttc
    25501 aaagtggaaa acctacattt gataaaccag atgttccttt agctaaagat gccttttcaa
    25561 tttcagatgt ctataataag gacttcggta atgcaagtgt tgatgcaaac actggtattg
    25621 ttacattcac tccagctaaa ggtgtaggag aatcggagcc gattactgga acaattccta
    25681 ttaaaattgt ttaccaagat ggttctgtag gcacgaccga tttagcagta actgtaagta
    25741 aagatattta tgaaaatcca ggagaaaaca ttcctgcagg ctaccacaaa gtaaccttca
    25801 ccgcagg
//
LOCUS       DAFEIE010000036        25695 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFEIE010000036
VERSION     DAFEIE010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.037"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(153..587)
                     /locus_tag="LP345_001682"
     CDS             complement(153..587)
                     /locus_tag="LP345_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760465.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(697..2556)
                     /locus_tag="LP345_001683"
     CDS             complement(697..2556)
                     /locus_tag="LP345_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL1760466.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(2674..3833)
                     /locus_tag="LP345_001684"
                     /pseudo
     CDS             complement(2674..3833)
                     /locus_tag="LP345_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(4140..5564)
                     /gene="araA"
                     /locus_tag="LP345_001685"
     CDS             complement(4140..5564)
                     /gene="araA"
                     /locus_tag="LP345_001685"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBL1760467.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(5580..6278)
                     /locus_tag="LP345_001686"
     CDS             complement(5580..6278)
                     /locus_tag="LP345_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL1760468.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(6235..7896)
                     /locus_tag="LP345_001687"
     CDS             complement(6235..7896)
                     /locus_tag="LP345_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBL1760469.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            8114..9514
                     /locus_tag="LP345_001688"
     CDS             8114..9514
                     /locus_tag="LP345_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBL1760470.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(9766..10845)
                     /locus_tag="LP345_001689"
     CDS             complement(9766..10845)
                     /locus_tag="LP345_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1760471.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(10931..11890)
                     /locus_tag="LP345_001690"
     CDS             complement(10931..11890)
                     /locus_tag="LP345_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL1760472.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(11902..13413)
                     /locus_tag="LP345_001691"
     CDS             complement(11902..13413)
                     /locus_tag="LP345_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL1760473.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(13435..13998)
                     /locus_tag="LP345_001692"
     CDS             complement(13435..13998)
                     /locus_tag="LP345_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL1760474.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(14004..14867)
                     /locus_tag="LP345_001693"
     CDS             complement(14004..14867)
                     /locus_tag="LP345_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1760475.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(14881..15777)
                     /locus_tag="LP345_001694"
     CDS             complement(14881..15777)
                     /locus_tag="LP345_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1760476.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(15952..17241)
                     /locus_tag="LP345_001695"
     CDS             complement(15952..17241)
                     /locus_tag="LP345_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1760477.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(17213..18730)
                     /locus_tag="LP345_001696"
     CDS             complement(17213..18730)
                     /locus_tag="LP345_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL1760478.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            18928..19818
                     /locus_tag="LP345_001697"
     CDS             18928..19818
                     /locus_tag="LP345_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBL1760479.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(19891..20715)
                     /gene="nadE"
                     /locus_tag="LP345_001698"
     CDS             complement(19891..20715)
                     /gene="nadE"
                     /locus_tag="LP345_001698"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBL1760480.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(20727..22199)
                     /locus_tag="LP345_001699"
     CDS             complement(20727..22199)
                     /locus_tag="LP345_001699"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBL1760481.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(22836..23198)
                     /locus_tag="LP345_001700"
     CDS             complement(22836..23198)
                     /locus_tag="LP345_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL1760482.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            23421..24173
                     /locus_tag="LP345_001701"
     CDS             23421..24173
                     /locus_tag="LP345_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1760483.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(24313..25236)
                     /locus_tag="LP345_001702"
     CDS             complement(24313..25236)
                     /locus_tag="LP345_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1760484.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(25251..25523)
                     /locus_tag="LP345_001703"
     CDS             complement(25251..25523)
                     /locus_tag="LP345_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760485.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         7508 a         5377 c         4334 g         8476 t
ORIGIN      
        1 aaaaggagta tttactcgat tttgagtaag tacaaggttg ttgttggtta taggtatgtc
       61 attatcataa aggattttga tcactctatc ataaaggtaa tattacattt atattagata
      121 actctagttt ttattgttat caaagatttc ttttattttt tcaacaacaa attagtcatt
      181 ttttggatgg cagctgtcaa ttggtctgtc gcttggtctt gttttgcttc agatgtattg
      241 aatagatctt catctacccc tgattcaaga tcgatacttt ggatcatttc ttcacagcct
      301 gctacatatg aaagataagc tttttcaaaa tttttatgaa tgcccattgc ttttgctggt
      361 ggacgcaaag tactgacttt cataagcatt gcccgatatt tttttgttcc ttcttcaaat
      421 aacaggatga tctcttcaag agtcgatttg tccagttcac ttgtttttcc ttcatcaatt
      481 gcgtttctga tcacttcata tttcggatgc attccttctc cgattgcttc tgtttccttg
      541 acgatttgat cgatggactg cacataatag ccaatattcg gtaacatgtt cgttttccta
      601 ctttctccat tgttgttatt atttattcta cttgttttta tcctcaaatg acaagtactt
      661 gaaaaaattt aatggtttct atacagctcg ccattcttat tcgtgctcaa agaaaccatc
      721 tgctaaacta tattgtttcc ctgcgacaat gtcatattgg atcaattgat attcgtcgta
      781 aatctcttgt tgcgagcgat tgaattgcgc ttctttatac cactgtccgt tttgatagta
      841 cagttctcgt tcaaacgccg gaagttcctg ttctaatgat aaaagcagct gataaaagcc
      901 atttgttgtc tgattcgtct gttccattag attcgctgca aaataaaacg gactggtgat
      961 tgcatcgtga gtcgtttgct tttctaattc tcctttactg tcgaacataa gaaattgtgt
     1021 ttcatgcaat gtttgtttgt cattttttgc ttggatcgta tctgaataga tccctggaag
     1081 atgatccccc caaaaaacaa ctaaagtcct tctagaaaga ttcttcaatt cttccgtgaa
     1141 ctgcttcagt gccgtgctgc tataggaaat atcttgcaga taattctcta agtcaagtgt
     1201 cccacttcca tctgaagttt ttgcaggata gtctagatta tcatactttc catcgtaggg
     1261 catatgtgtc tgcatcgtga ctaaatgaat gaactgaggt gttttttctt ccttgagaag
     1321 tgtcattact tctttgtaag ctgactcatc agaaatatat ggattattct ctatcgtatc
     1381 cgtataggtc atcgtacgct cgctgatgaa ctggtcaaat cctaatgtct gataaacatc
     1441 ctctctttta tacatcgaag tattgtatgg atggatcgct gtcgtctggt atgattgtgc
     1501 gtttaacgct gaaacgatag aaggaagctg atccattttt ggtacaagca tcgtgtaagg
     1561 ggtggtgagt tgcgcattaa ataacgccat agaaaaacca gtcaatgctt caaattcgat
     1621 atttgctgtt ccaccgccat agttttgaga aagcatattg ccactatatg tttgatcagc
     1681 tacttcataa taatctgcca atggctcacc agatacttct acgccgttta atcgactagg
     1741 atctgagaaa ctttcactca tcacgaacac gatgttcggc gactcttcct ctacagtttt
     1801 atttttttca tcggctagct tctggtattt ttcagtgatt tctttgatct tttctttcga
     1861 atatccttca ggttcatcca ttggttctac cttcagattg tacaaaaacc caccgataaa
     1921 accagtgtta tagtagttca ttttctggct gtaaggtatc catagtgccg ttttattata
     1981 tgcttttcgc aacaaattat cgggattgtt gaaattactg atatacccta gcagtccaat
     2041 tgccacaagc agtgtcgtta atcggatcaa ttggaatcgc cttccttttt tcaggcttcg
     2101 aaacatgtac cagcaaaaca atcctatcac ggttcctgcg gcagctaaga tcactgtaaa
     2161 cagcatagtg ccggtcatat ctttcagcaa tccgatttca gtgatcatct tcaaatcgtc
     2221 tggataaatc ggttcttgcc gataactcat tttcatataa tttgcaaaac ctaatacacc
     2281 gatggctacg acatacgtaa gggaacctaa agggacagat cctgctagtg caatcagaaa
     2341 aataagaata atcagcaaga cgagacaggc taagaagaat ttttccgtat gccaagaaaa
     2401 agcaaatttc aacgcaaggt ctacggatag atcattttga caccactgca aaaataaatt
     2461 actaaaaaca acaagaaaaa agatactgat gattgctgct gttcctttta aaatcttttt
     2521 ctgtttggtc gaaagtctgc ttatatatct tttcaaatgc ttgctccttc atttctatca
     2581 ataaaagaat gttgcttctc ttattttagt tgtacgaaat tcgaaagtaa agaacggaaa
     2641 gaagaattaa tgaaatccaa atattctctt tctttatggc ctttctggtt tctttaataa
     2701 gcggaccttt cgtactccag aaattttttc tagctgttgt ttcacttgat tgagctgttc
     2761 aaaatcagta ctgtctatgt caatcaatat gtagacatgc tcattcttat ggttacgcga
     2821 tatatctgcg atcgctagct cgttctcatt cagcagagaa aatatctctg ctaatatatt
     2881 ggttttcttt tgataaaata tagtgaatcg aaacggcgct tggaaaaaca ttcgtgcgga
     2941 tggataattg accgcttctc taaccgtacc gaacaaaaga taatctttta aggcttcaac
     3001 tgccaaacgt ccgctgtctg ccaaagcttc ctgagtcgat cccctagatg aggcaacata
     3061 agtatacggt cattttctaa gaactcttct tctggaaaat cagtcaagta tttagccaga
     3121 tgttgttttt ccaatgcttg cataacagca tatttatcaa caatttcact tcttcctaca
     3181 ttgataagta cagcatcttt tttcattttt tctatattcg cctgatcgat caatcctttt
     3241 gtatcttctg tcaacggcag catgactacg atgtaatccg aggtagaaag aactgtttct
     3301 aaatctgctt gccgaacata atccaactgg gcatcgcgga tagaataacc caagacatcc
     3361 atccctaagc tatagcaact tagcgctact tttgtgccta tcgctccaag accaagaaga
     3421 ccgatggttt tgccttgcaa ttctcgtccc acataagcac ttcttttgtt ttctgcctgt
     3481 tctaaaatat taggacctgt tagtgtttgt accatacgac ttgcttcgat tatcggacgg
     3541 gaagataaga gcaaacagca caaaacaagc tcttttactg cattagcatt tacacctggt
     3601 gtattcatga cgatcgtccc gttttcagaa gctttttcaa cgttgatcgt gttcacccca
     3661 acaccagctc ttgaaattgc tagcaaatct ggtgtaagcc attcatcttt cactttcgta
     3721 ctacgaataa ctattccttc ggctggcaaa tcatctatta ttttgaaata ttccccttgt
     3781 aacttttcta tctcttgttc tggaatagca tcaatcaaat gaacgtgata cataaaaccc
     3841 cctccttact aacaagtatc tcgaaatttc tgcaattaga caactgttta ccatttgact
     3901 tcctagaagc aaaaagagca gttagagcag agtaggctga gtgataaaaa taaggctatg
     3961 acaagttact gccataagcc ttattttcga gagcaaaata ttgagggtga gatatcttga
     4021 taaatggtgt tccgttagct gacattgata ataagactaa atttcaaaaa agttgaaaag
     4081 caaatttcgt caatctcttc ttatttctta aaactaagtg gctttttcac aacctctttt
     4141 tatctaataa ccactgtttc caactcaact aattttgccc acgtttcaat ttgatctgtt
     4201 gttagattta gcgagacaac ggtatgatga ccgccacctg cctgaatcca tgaatggaca
     4261 ccttcatgga aattcggttt agttttccat aacacacgtg caacaggtaa attaggtgct
     4321 tcagtcgttg gttcaaaggc ttctacttca ttgatcagca gtttataatg cgtaccgaaa
     4381 tctgccatcg atacgactac cccttctcct gctttcccat caaatacaag acgcgccgga
     4441 tcttctctat ctcccattga taaaggagaa acaacgattc ttggtttcgt cgcagcaagc
     4501 gtcggatcta cttccatcat atgggattcc aagattgctt cttggccact agctagctcg
     4561 taagtataat cttccatgaa tcctgtatct ttccctcgag ccatgatttt cagcaaccga
     4621 tcaatcgctg cagttttcca gtcgccttcc ccagcaaaac cgtatccttc tgccatcaaa
     4681 cgttgtacag ctagtccagg tagttgtttc attccataca ggtcttcaaa attagtcgta
     4741 aaagcgttat agcctccttc ttctaagaaa cggcgaatac cgatttcctg ctgagcttgt
     4801 acttttacat gttcctccca tgtcttttct tcataatcac catagtcgaa ggtatacaat
     4861 tccttgtact cttcaaataa ttgatcgact tcttcgtctg atacgcgatc gattacttgt
     4921 acaagatctc cgataccaaa ataatcaaca gtccaaccaa attgaatctg tgcttccact
     4981 ttgtctcctt ctgtgacacc cacgtttctc atgttgtcac caaaacgagc cacttttatt
     5041 ccaaaacttt cattataggc tactgcaaca tccatccaat cagcaatctc tttttggatc
     5101 tcaggtcgtt tccagtagcc aacgacgatt ttattttgtt tatttaatcg agcattgatg
     5161 aacccatatt cgcggtcacc atgagcggat tgatttaaat tcatgaaatc catatcgatc
     5221 gttttccaag gaatgctttc gttatattgc gtagctaaat gaagcaatgg tttttgtaga
     5281 agctttgtcc cgcggatcca catttttgct ggtgagaaag tatgcatcca agtgatcaca
     5341 cctgctactt cttctcgata attgacctct ttcatgattt ttgtgatcgt atcagcagta
     5401 actgctaatt cttgaaggcg gattggataa ggcaattggc cattttcatt cagttcatcg
     5461 accatttctt gtgcatgttt ctttacttct cgcagtgctt cttccccata taaatgctgt
     5521 gatcctacaa caaaccaaaa ttctttttct ccaatattca acataattag ccactccttt
     5581 tatttgtttt gtccgtaata cgcatttttt ccgtgttttc gtaaataatg tttatctaaa
     5641 atccgttgag gcagctcttc tgaaaatgaa ttgagctgtc tggtaaataa attcatcttg
     5701 catacttcat ctagtacgac tgcgttcatt accgcacttt gcgcatcttt cccccaagta
     5761 aatggaccgt gtccgtgtaa aagtacccct ggaattgcta agggatcaat tttgcgttct
     5821 ttgaatgttt ctatgataac ttttcctgtt tcatattcgt acccgctgtc gatttcctgt
     5881 tgtgtcaaaa atcgagcaca aggtaccgat ccataaaaag tatctgcatg cgtcgtcccc
     5941 atcgcaggaa catccaatcc tgcttgtgcc cagatcgtcg cccatgtcga gtgagtatgg
     6001 acgattcctc cgatttgagg aaatgaacga tataaaacag catgagtagg cgtatccgaa
     6061 gagggattga gtttaccttc aatgatatga ttgtccaagt ccacaacgac catgtcgtct
     6121 gctgtcatct cttcataact gactccgcta ggtttgataa cgaaatatcg tgtttcagga
     6181 tcaaaagcgc tcacatttcc ccatgtatat ttgacgagtc cgtgtttagg caagtcaaga
     6241 tttgcttggt atacttcttc tttcagttgt tccagcattt tctatcactc ctttttcttg
     6301 caattgatga atcgctgttt tttcaatgtc gatcccctca cggtaacgtc tcataaatat
     6361 ctgatagcct gctatttctt ctgctgaagg tgtgatggtg attccttggt cttgtccaaa
     6421 cacgtcttct gccaagaagt tttctaaaga cttcccatgt cgatccatca tataggctgc
     6481 taataacgcg attccccacg ctccaccttc tccggctgtg tccatcactg taactggtgc
     6541 ctccatagca gatgctagaa tccgctgtcc aacttctggt gttttaaaaa tccccccatg
     6601 ccccactaaa cgatcaattt ggacattctc agatttcaat atatccattc cgattctcat
     6661 tgcaccaaaa gcactggcta aatggatccg catgaaattc gctaaatcaa aacggctacc
     6721 tggtgtacgt acaaataatg gccttccttc atttactcct gtaatgtttt caccggaaaa
     6781 ataaccataa gaaagtaatc ccccgcaatc cgtatcgcct tctagcgctt tgttgaataa
     6841 taccgtgaat aatttatctc tgcttatctc catacccaaa gaattggtaa attcttcaaa
     6901 aatactgacc caagcattga tatccgaaga gcagttattc gtatgaacca tgcctactag
     6961 ttctcctgaa ggtgtagtga ccatgtcgat ttccggatgg acattttcta gttctttttc
     7021 taatacgatc atagcgaagg cggaagtacc agccgaaatg ttccctgtcc ctttggctac
     7081 actgttcgta gcgaccatac cggttcctgc atccccttct ggcggacaaa ccgggattcc
     7141 tggtctcaaa tttcccgtag ggtcgatcag ataagcccct gattcgctta acttgccagc
     7201 ttcttctcct gctactagaa ctttaggcaa aatgtgatcc aagtcaatcg ctacgtgcgc
     7261 tttttcgatt aactgaccaa aaatattttt catttcttga tggtaggttt tcgttgaagg
     7321 atcgatagga aacatgcctg atgcatctcc tacgcctagt actttctcac cagtaagctg
     7381 ccaatggaca taacctgcaa gcgttgtcaa aaaattaatt tctttcacat gttcttcttt
     7441 attcaaaata gattgataca aatgagcgat actccatctc tgcggaatat tgtattgaaa
     7501 tttttccgtt aatattcgtt ctgcttcttc agtgattgta tttcgccaag tacgaaatgg
     7561 tactagtaac tgttccttgc tatcaaatgc tagataaccg tgcatcattg cactgaaccc
     7621 aatcgacccg attgtcgtaa gattctcgcc atagatttcg aatacttctg ctgccatttt
     7681 tcggtaactg acgcgcagtc ctttccaaat atcttctaat gaataggtcc agataccatt
     7741 ttctagtttg ttttcccact cataactacc agcggcaata ggagtaaaag atgaatcaat
     7801 caatacagct ttgatcctag ttgatccaaa ctcaatccct aaagatgtac gaccatctat
     7861 gacatctaac atactttgcg catttacttc cttcataatg atttaactcc ctccttctcg
     7921 tcaaacctga tcaaaccgtc tttttagtag cgcttacaat gattattgta tacttttgta
     7981 cgtacatgtc aagcagttat ttacaagaat acaataaaaa acacttgttt tgtacgtaca
     8041 taagttataa aatgaaattg cttacaaaat ctgatcaacc gccttctcga aattctagaa
     8101 ggagagaata cttatgaaaa aagaaaaaaa agtttcctca tcgtttattt atttttttgg
     8161 cgcatttggc ggcattctat ttggatatga tattggtgtt atgaccggcg ccttaccttt
     8221 tttacagcat gattggggtt tggcaggtaa agcttctttg ataggatgga tcacgtcttc
     8281 ggtcatgtta ggtgcgatcc ttggcggctc tttatctggt cttctttctg ataagcttgg
     8341 acgacgaaaa atgattcttc tttctgcact tatttttatg gctggttctg tcctttctgc
     8401 atctgcccct cacaatggtt cttattttct gattgcagca aggattcttc taggtttagc
     8461 tgttggcgct gcatctgccc tagttcctgc ttatatgtct gaaatggctc ctgctagact
     8521 aaggggaaga ttgtcaggga tcaatcaagt gatgattgct tctggcatgc tcctttccta
     8581 tgttgcagat tatttgctaa aagggttgcc tgaaacgatg gcttggcgcg tgatgttagg
     8641 gctcgctgct gtccccgcgc tgattttatt tttcggtgtt ttagctctac cagagtcacc
     8701 gcgttttctt atgcaatctg gccgcttgga agaggcaaaa agagtattga actatattcg
     8761 gacaccaaaa gaagctgaac aggaattcga acaaatccag ctgaatgtca aacaagaaaa
     8821 gacaaccgga acttcttggc atactttgtt tttagaaaaa tatcgttcct tagtcattgc
     8881 cggtattggt gtagcagtat tccagcaatt tcaaggagct aatgctattt tttactatat
     8941 tccgctgatc gtagaaaaag cgactgggca tgcagcgagc gatgcattga tgtggccgat
     9001 catccaagga atcattttag ttgctggttc tttgctcttt ttggttattg cagacaagtt
     9061 caatcggcga actttattga aaataggcgg tagcgtgatg ggactttctt tcatcctacc
     9121 agctgtttta ggaactgtac tggatgctca tacaaattcg ttgttgattc tcttgttttt
     9181 atgtatttat gtcgcatttt attcttgcac atgggctcca ctgacatggg taatcgtagg
     9241 cgaaatattc ccactagctg tccgcgggcg agcatctggc ctagcctctt cttttaattg
     9301 gattggttct ttcctagttg gcttgctttt tcctgtgatg actgcttcta tgtctcaaga
     9361 aatcgttttc ggcatttttg ggatcatctg ctttttaggg gttttattta ttcaagagat
     9421 cgtaccagaa actcgtggga aatctttaga ggaaatcgaa caaagtgcat ctaaaaaaac
     9481 ttatcctaaa cgtatttcta tccatcattc ttaaagaggt tgtgacagaa gtggtcagct
     9541 tcaagaaata agaaggaacc gcttagtttc cagtcacaag gaacaatttc aaaaaacagc
     9601 ttctcatgtt tgatgaatat tgtgacttgt gaccagttgg taggagaaca ccgtttagtg
     9661 gagaggtggt gaaagaaacg ttcagccttg agcgatgaca aaagctctca caaacattgc
     9721 gacgagtaac cgtaggagca ataagaggcg gtaaaaaccc gtctcttatt tttcgttttc
     9781 tttcactgtt tcccgttcaa ctagtacagg ttcatagaga atatttggct gtgcctgtcc
     9841 tttttcaatc gttgtgacga tccaccgtgc ggcatcttgt cccaactttt cttttggatg
     9901 cgtcaatgtt gtcaattttt tattccctaa atggcttaaa gaagaatcgt ctgttcctac
     9961 gatcgatagg tcatctggaa tatgatagcc attttctgtc aacttatcta gcattaaact
    10021 agctatttga tcgttatagc aaatgatgcc atctaaagct tgttcttctt tcaaccgttg
    10081 tactgttttt tcagcgattg tttctcgtgt ttccgtggtg aaagtaatga tatcttccgt
    10141 caaaaaacgc acattatact gttcacacgc gctgataaaa cctttcatcc tgtattttcc
    10201 ttgaagatcg tcgatttttg tgatgaacaa cagacgctga tgtccttttt ttatcaaata
    10261 ttctgctgcc ataaaaccga ctttcacatc atctaaacaa atataagagg catttaactc
    10321 ttcataagca gcattgatca tcaccatcgg aatgccttgt tctctcaaag caacataaag
    10381 tgctaagttt gggttatact gattactttt cgtaggctca acgatcaaac catctacccc
    10441 ataagcaatc attttcttca aacactcttt ctccaattcg tgatcgttat tcgtactggc
    10501 taaaagcaat gaatacccag attctcgtaa ttcattttcg attcctcgga taatcgacgg
    10561 aaaaatataa tcagagagat atgtggtgat gacaccgatc gtttttgttc tgttcaatgg
    10621 tgttttttct ttcttatagc tgtcatctac atatgtgccc gacccttttt ctttacgcag
    10681 atagccctca tttaccaaca cagcgattgc ttgccgaatc gtatgtctgc tgacgtcata
    10741 tatttcttgc agcttgaatt ctgagggaat ggttgtattt acttcgtatt cctcacgaag
    10801 gatcttttgt tttatctctt ctgcaatatc ttgatatttt gccatttgcc ttgccccttt
    10861 ttatttgtac gtacatatat cataacgagt ctgcaaggtt tattcaagca aaaatcaagg
    10921 tttcttgtgc tcataaggca tacggaacag gttcaccaaa ttctggaaat ccttgctcat
    10981 tccacgtaaa gcattgcgcg ttcgcgtgcc gattaggatt gtctaacgga tccccttttt
    11041 ggttcttctc tggtcgagca tgatagatca aaatatcaaa gcacccgtct tctgaaaccg
    11101 taaacgagtt gtgaccagga ccaaattgct tatttttttc agaagaaacg aatactggct
    11161 ccgataattt atgccatgat tcttttaata aaagattctt gtgctcatca gcccacagca
    11221 ggcccatggc atagttttca tctgttgcac taccagaata cgtaatgaat attttcccat
    11281 tgcgagtaag gactgctgga ccttcattta ctgaaaaacc ccgtttttcc cattcatact
    11341 caggtataga aaggaggatc tgcttcccct ttaacgtcca aggattatcc atttcggata
    11401 gataaagatt agaattccca gtaatttcag gatcttgttg ggcccacaca taatatagct
    11461 ttccttgaga agagaaagtt gttccgtcta aactgaaagt ttcccttttc gtttttattt
    11521 gtcccttttc tatccaatct gtattcattg gatctatatg ctgattttca agtacgaaca
    11581 tgcggtgatg atgagattca tcacgtatag ttttatgatt gcttgcagca aagtaaatat
    11641 accattttcc attgatataa tggacttcag gtgcccagat caattcactc atcggtcctt
    11701 cttcatgagc ctgccataca atcaggcttg cagcatgttc taattcattc agtgactttg
    11761 cccttcttaa ttcaatcact tggtagcctg gaaccgatcc tgtaaaataa taataaccat
    11821 ctgtatgttt atatacccaa ggatctgccc gttgccgaac gataggatta ttataaagtg
    11881 tcttcatcat aacaaatttc ctcacatttt ctttattcta attacattcc aagagtattt
    11941 ttctatccct acatttaatt cgtcatgttt ttctattgaa aaatagttta tttcaggttt
    12001 tattttttct ggttcttcac gtgtattttt gtccaacaga tcgctactgg ttaatgtgta
    12061 gtgctctcct tgatctagca aattgaaatc atgttcaatc gttatctttt gttgttcatt
    12121 tgtgcgattg atcaagaaaa tagtcagctg attgccgtta tctacgatca cactgtccac
    12181 ataaggaaca ttttttatct tttcacaatc ataaacaggg caaatgattt gttgtttcaa
    12241 tacttgacct ttagcatatt tcgataagtg ttgcatcaca taataagttg gattcctcca
    12301 tgcttgtcct ttagcatctg tcagtattaa aggtattgtg tttactaaca atgattgaca
    12361 actaatcttt acgcgatctg cgtgtcgtaa aatagccagc cctaatgaac caaataataa
    12421 tgtatcttcc atagtaaagt aacaccaatc gatgggacta ccgacttcaa aatccctatg
    12481 tcttttttcc ggttgggcat gtacattcca ttcatcaaac gctagataca ttgttttctc
    12541 acttctcaaa tatcctttta cataatcaca agtagcaacg atttcttcaa tttgacgatc
    12601 gaatcgataa gcttttgcaa ggtatgtcgc tgtatcatca cgctcatttt taggaggttt
    12661 agtcaagtct tcttcatcat acttatcaat atagttatgc aaagctaaat aatctacatt
    12721 ctcataagct tcttctaatg cgatacgatc ccattcaggg tacgatggta aacgtggcgt
    12781 agagcttcca actaagattg tttcaattga atcatccact aacttcatga cttttgaggc
    12841 ttcatttgct aacctaccat attcataagc actcttagcc cccacttgcc atggaccgtc
    12901 tagctcattc cctaaacacc ataatttaac gccaaaaggc tttttttgcc cattttttat
    12961 tcttaaatca ctccagaagg ttccttttgg aaaattacaa tattctacta aattttttgc
    13021 ttcatcaatt ccttttgttc ctaaattcac cgtgaatatc ggtttcgctt gtacatgact
    13081 gatccattta aaaaattcgt ggagtccaaa agaatttggt tctatacctc gccatgctaa
    13141 atcaattttt tttggtcgtt gttctttcct acctacagta tccacccaat cataaccaga
    13201 tgtaaagttt cctccaggat agcgaatgac acctaattct aattccttta cataagagag
    13261 gacatcttgt ctaaacccgt caccatcagc tgtttcatgg cccggttcat aaatccctgt
    13321 atagacgaca cttcccatat gctcaacaaa tgagccaaac agccgagaac tgatctctcc
    13381 taccgtaaaa tcctctctga tttttacttt cacttcttcg tccaacagct ttccctacct
    13441 ttcatttcct atagtcaaga taatagatac aagtttccat acgccaccag caaagataaa
    13501 aataaaagga gggaaaagaa atatgagcag tacaaatcct aataacaata cgcaacaaag
    13561 aatatttctc aaaaaatcaa aaaatacttt ccatgcactt tgttcaaaaa tttgtaaaaa
    13621 tgtgatatct ttgttttcag aaatcacata tatccaggat aaaagaaaca tggaataaat
    13681 aagtaaaact acatatccac taattgaaag tacgattgtc tgttcttcta ataattgatt
    13741 aacaagaaaa taaataatga tcgttaacag actaaggaac aagttcttac caaaatgttg
    13801 ctttattcct tgaaagaaaa aataaatgat atttcctgat ccctcacctt tccattgcgc
    13861 cattacataa aaaacagcac atgtagcagg cacgatagta ataacaggca aacacacgat
    13921 tacccagaga atacctaata agatgtaatc agaaaccaca atcaactgtc cataaagttt
    13981 agtctcaact attttcatct tcctcactct ttcattccag acatagctgt tccttgaaca
    14041 aaatatttct gtgcaaaaat ataaaccact agtaatggca gcattgaaat aaccgttcca
    14101 gccattacag gtccataaaa agaaatgttc tgccctgtaa ataaagctaa ccctgctggt
    14161 aaagttctca tttttgaact acttgtcaat atcaatggat aaagcaagtc attccaacta
    14221 ttcatcagcg tgaaaatccc taatgataaa agagtaggtt tgctcaatgg caacatgatt
    14281 ttcaaaaaaa tattaaactc acttaatcca tcaatgcgtg ctgcctcttc caaagaatct
    14341 ggtaaagtaa taaaaaagga acgcatcatg aagataccaa atgcagttgt catacgagga
    14401 atgatcaaac ctgcataagt atcaagcatg ccaagcaaat tgacttcaat aaatagagga
    14461 atcatgaaga cttggaatgg gatcatcatt gtcagcaaaa cgaaatagaa caaaactgat
    14521 tttcctttga aacgcatacg agcaaatgca taccccgcaa gagaatcaaa gaatacagaa
    14581 gtgatcactg tccctccagc aaaaatcact gtatttttga tgtaatctaa taaagggatc
    14641 gttgtccaaa ccttaatata gttatctagg gtatagctat ctgcaaatat tctaggcgga
    14701 aatgagataa tgtctttttc gtgtttaaaa gaagaaataa tcagccacaa aaaaggaaac
    14761 gcaataacca acaatataac tagcatacta atcgttcgaa tgattttttt accactaact
    14821 gcttttcgac tattcacagt aactgtaatc gagctttctg gtgccataca ggtttccctc
    14881 ctatttcatt tgtttttctt tccgtgacat gtacacatta gtggagatag ctatagttgc
    14941 aacaatgata aacaaaaccg aagacagtgc tgatgcatag cccaattcat aaggtgctgt
    15001 aaatcctcga ctgtaaatat attgaacagc tgtttctgtc ttaaattgtg ggccaccagc
    15061 ggttgcaaca tatacttggt caaacacttg catcgaacca atcagattcg ttaaaataca
    15121 aaaacctaag gagggaacga tctgaggtag cgtaatgtta aaaaactgct gtcgatttgt
    15181 tgcaccatcc atttgagcag attcatacaa agagggagag attccctgaa tagcagtcaa
    15241 gagaatcgtc atagtaacac caaaattctt ccaaacagtc atgatggcta ccgtcggcat
    15301 agcaagggtt ggatcgcgaa aaaattgagg gatcggcaag ccgacttgtg aaaacaagta
    15361 aggaatcgcc cctacattcg gatcaagcaa catagaaaaa ataatcgcaa ttgacgtcaa
    15421 tgaacaaata actggaatgt aaaatgtcga acgacaaaaa cgattgaatc tggtattttt
    15481 agataatgct actgctgcta ataaaccaac gataatttgt gttggcgttt cgagtacggt
    15541 gaaatataaa gaatgaatca acgaattaac tgctcgttca tcactaaata tacgtgtgaa
    15601 attttcaaaa cttacaaaat ttcttgatgt aaagaaaata ttcaaatctg taaaactaat
    15661 agcaaatgtt cctaaaagcg gtatgacagt aaataataat aaaactaaaa aagatggagt
    15721 taaaaacaaa tacgcagcac gatcaggacg attccaatat ttggtgaatc cgttcatata
    15781 gtccacctca tctttcattt tgataaaata tacaatcttg gtttaaacga atctgaataa
    15841 gatatccgaa caatcgctgt gatttttgca ataacaccta tctgcaaata ctaggtcgat
    15901 cattcagata tctgtatctt gccaacagtc tatcctgtat aaagttctgt actatttttg
    15961 cagtaattga ttgatggcat catctgcatc gttcatgagt gtctcaggat cttctcctgc
    16021 taataatttt tcaatcagtg gattgatgat atcgttattg atcgcagaga tttgggtaaa
    16081 acctggtaaa tatggctctg catagtccat ttgtttcgat aattcagata caataggatc
    16141 attttttact tcttcatctt ttgctactga atccaagtag gcaggaaaac cattttcgat
    16201 actccatttt ttaccaattt cagttgtatt ccaatatttc aaaaactcat agacagcttc
    16261 ttttttatta ttatctgtac ttgccggaat ggcatatcct acgccatcta aaatagctgt
    16321 ttttttgtct gaatcactcc cttgtggtaa ggtagtcaca ttataatcaa tctcgtttgc
    16381 tttcaatccg ttatttaacc atggcccatt gatttcaatg gctagttgac cagcattcat
    16441 taaattgtcc atttcggcgc cagaaatcga ttctggacca gtcttgtcta catggatcat
    16501 tttttggatc gcttttaacg ttttaaggtt ctcaggagac gcaaattcag acttagtata
    16561 atcatcgttc actaatttac cgccatttgc taacatccag ttatataacg gtgcagttcc
    16621 atccttattg aagacaaaac ctgatacatt tttactacta tcagttaatt ttggtgccat
    16681 ttctgtcaat tcttcccaag tagtaggtgg ttgttcagta tctaatccag cttgtttaaa
    16741 caaatcatta ttccaataca tatacatgcc ttgtacctgc atggggacaa aatactgttt
    16801 accttctact tcacctaatt caatagccgt ttctttaaaa tcagatttat ctactccatc
    16861 atattcccag aaatcgtcta atggttgtac cgctccgttt tctacatact gtgcaaaatc
    16921 tggataattt aatgcaataa agtcaggtgc ttttttagaa gaaatcgctg taggaagttt
    16981 ttcattcaaa ttggcccaag tcatgatatc catttcaatt ttgatgtttt tatcatttgt
    17041 tttattaaat tcattaacga tttcttgcaa tatttcacca tcagatgcag taaacccatt
    17101 ccaaaaagtc aaagtcactt ctttatcaga atcagattct gctgaacttc cgccaccgca
    17161 agctcctaaa atacctgttg cagctaccaa caaagagcca attaaccatt ttttaccttt
    17221 cattttttgt tcctccttca tctgataaac gacatctgac cacattccaa gatagcggtt
    17281 tcaataaaca attgattttc ccatcttcag cttttacatt tgttgaatga cttggtttta
    17341 cttgttcact tttaggaaga ttagttgctt ttgtatcaaa tccactcatt tcagaaaaat
    17401 caatcactcc ctctaatgat aattcagaca agtgaacagt tagattcatt tcttcttctc
    17461 cacggttaac tgcaaatatg acaagttctt tgtcatttat tacggctata ctttctaaat
    17521 acggcacttc ttcaaaatct tccgtcgcat agtttgctga acgaatttgt gggcttaaca
    17581 cctctccttg tccatacaca gcagcttgca taaatggata atagatcgtc tgtctccaag
    17641 cttctccgtt tgtttctgtc ctgattggtg caataacatt taccaattga gcaagacaag
    17701 caatctttac tctatctgca tgtttcaata aagtgattaa tagacagcct aatagtaatg
    17761 catcttcaaa attatagtta tcttctagta aaggaggagc aatctgccaa ggcgctgctt
    17821 gctcatcttg ttccgctgaa tgataccaaa tattccattc atcaaaggac aggttgatct
    17881 gcttcttact atgtttcttc gccttgactg tatcgcacat cgctgtcact tcagaaatga
    17941 accgatccat gtctaaggaa cgtgcaagat aatgagaaag atcatttttt tggttgccat
    18001 aatattgatg cagagacaaa taatctattt gatcgtacgc ttgatcaaga actgttaact
    18061 cccaatcacc aaatgtaggc atttgccgat tcgaacttcc gcataaaacc acctcaattg
    18121 aatcatctac gagtttcatc gccttagccg tttcctctgc taaccgtcca tattcttccg
    18181 ctgttttatg tccaatctgc caaggaccgt ccatttcatt ccctaaacac catgtcttaa
    18241 ttccaaaagg gctctcttga ccattcgaac gccttaaatc actccaataa gttcctttag
    18301 gaaaattaca atattcgact aaattacgag ctgcatctac tccacgagta cccagattga
    18361 cagccatatt gatttcggcc cccacatgct gacaccagtt ataaaattca tgaatcccaa
    18421 cttcattcgt ttcaattgtc cgccaagcta aatccaacct tctaggtcta tttgctatgg
    18481 gcccaatact gtcttcccaa cgaaatcctg acacaaaatt tccaccagga tatctaatca
    18541 tgggaatgtt caattctttt accaagtgaa tgacgtcttg gcgaaatcca cttttattag
    18601 ctgatggatg atctggctga taaatccctt catatactgc tcgtcccata tgttcaataa
    18661 atgaactgta caaccgcgga tcaactttgc ctacacgctt gacactacta atcaacattg
    18721 tggcttccat aactgacctc ctttaattta tacatgaata atacacctcg ttgaaagcgt
    18781 tgtcaataat ataaatgtta aacttactta ttttttatcg attttaatta accaaaatat
    18841 taataatgat taaaacaaat aatttaatat aacttttatt aacaaatatg ttaatatata
    18901 agaaaaacct tttaagaggt gatatatatg caactacaaa taaacgaaga atccttaccg
    18961 gtatatgaag cattagctag taaaacaagg atcaagatca tccagctact ttccaaaaaa
    19021 aagatgaatg tcaaagattt ggcaaaagaa cttggagtga gcagtgctat cacgacgatg
    19081 cacgtgaaaa agctagagga agcaaacatc atcaaaacag aaaaagtagg acaacaaaaa
    19141 atttcgagcc ttcgtgtcga taaaatcgat atcagttttc cagaaaaaat attcaatgct
    19201 tttgatacga aagaaacatc gatacctatt ggtcactata caaattatgc aattgaacca
    19261 acatgcggtt tagctacgat ccatgatttt atcgggaaag tggatgaacc acgctatttt
    19321 atggatcctc gaaggatgga tgcccgcatt ctctggttta ccagcggatt tgtcgagtat
    19381 caggcaccta attttttaaa tacagaggat acattggaga tgttggaagt ttctgtggaa
    19441 atttcttctg aatttccttt ttcaaatgac aattggcctt cagatatcac tttcagccta
    19501 aatggtgtgg agctaggaac atggacgagc cctggagatt ttgctgatat ccgcggtaaa
    19561 tatacgcctg attggtatcc agataatctt aatcaatacg gcttgctgaa gacgatccga
    19621 attaccaaac acttgacgaa tatgaatgga gaacccttgt caaacatcac gatcaacgac
    19681 atccctaaag agcaagacac ttggcatttg cgaatcgaag tgaaagacga tgccaaacat
    19741 gtggggggct gtactttatt tggtaaagga ttcggtaatt acgatcagga tatcaaatta
    19801 aaagtttact acagctgata tttttctttt ctattttata aaacaaaaac agccaatccc
    19861 tatgaaggga cggctgtttt tgctttattg ttatttccag aaatcatcca aaacggaaat
    19921 tggcaaatgt cgtttatgtt gtgtcttgtt ccaccatgct tcgatttttt cttgtgcttg
    19981 agcgggaact tcttttcctt ctagataatc atcaatttca ttatatgtga cacctagtgc
    20041 gacttcatct gcaatcattg gtttcccatc ttcaagatct gcagtcggaa tttttgtgta
    20101 taatttttcc ggtgcattca atgcttgaag caattgtttc ccttgtcgtt tgtccaaacg
    20161 gaataatggc aaaatgtcgg ctccaccatc accaaatttc gtgaagaatc cagtaatgtt
    20221 ttctgcagca tgatctgtcc ctaatacggc tcctgctctt tctccagcta cggcatattg
    20281 cgtaatcata cgttgacgtg ctttgatatt tcctttgtta aaatcgctga ttcccacacc
    20341 tgcttcgctt aatacttgta cttgtgcatc aacagctggt ttgatattta ctcgcagact
    20401 aacatcgggc tggataaagt caagagcagc ttttgcatct tcttcatctg cttgttcacc
    20461 ataaggaaga cgaacagcga taaattgata gttttcatct tttgtttctt cacgcatttc
    20521 ttccatcgtt agttgcgcca aacggcctgc taaagtagaa tcttggccgc cgctgatacc
    20581 tagtacaaaa gttttaagaa acggatattt tttcaaatat gctttcataa agtcaatact
    20641 tttacgtatt tcttcttttg gatcaattgt tggtttgaca cctaattcat tgataatttc
    20701 tgtctgcagg ctcatttatt ctcctcctat gcttctgtat gaagttctgc tacgcttttt
    20761 ttcattcgtt ccatgatagc cattttatgg ttccagcatt cagtagacag atcgactggg
    20821 tatttttgcg gattcaagtc tcgtttatac tcttcccata gtgaatctag attttctttt
    20881 gtatattctt tgatttcgtt tagtgcaggt aattcgtaaa ctctttttcc ttcgataaag
    20941 atatcttgta aaactgggcg agctgtaaag tctcgaacag ttttattgat aaacgtatgc
    21001 actggatgga acatgaagat agcttcttct tctcgagggt cttcatccca taatgtcacg
    21061 tagtctcctt cagatttccc atcaaaattt cgagtgatgc gccacacttg ttttttccct
    21121 ggagtagtta ctttttctgc attgcttgat aacttgatcg tatccatcat ttttccttca
    21181 tcatcttcga tcgatactag cttgaatact gcaccaaggg ctggctgatc ataggctgtg
    21241 atcaattttg tcccaacacc ccatacatca attttagctt tttgcatctt taaattcaaa
    21301 atcgttgctt catccaagtc attcgaagca tagatttttg cttccgtaaa tccggctgca
    21361 tctaattgtt cccgaacacg cttagatata taggccatat ctccactgtc gatgcgtacg
    21421 ccttggaagt tgattttgtc acctaattct ttcgccacgc gaatcgcact tggcacacct
    21481 gatttcaacg tatcataagt gtcgactaag aacacgcagt ctttatgggt tttagcgtag
    21541 gccataaatg cttcataatc atttccataa gattggacta acgaatgagc atgggtcccg
    21601 ctagctggta tcccaaatat cttcccagca cgtacattgc ttgttgcatc tgctccgccg
    21661 atatatgccg ctctagttcc ccagactgct gcatccagtt cttgtgcccg tctagttcca
    21721 aattccaata gtggatcttc tccgatgaca gatttgatac gagctgcttt tgtcgcgatc
    21781 aacgtttgga aattgaccat attcaacagt gctgtttcta ctaattggca gtgcgctaaa
    21841 ggcccttcca cttggattaa tggttcattt gcaaaaacta gttctccttc acgagcagaa
    21901 cgaactgttg ctttaaattc aaaattttgt aaatactcca aaaaaccttc aggatagact
    21961 tctaatccac gcaagtaagc aatatcggaa tcattgaacg tcagattctc taaataattg
    22021 actaaccgtt ccaatcctgc aaaaaccgcg tatccgtggt taaaaggcat ttctcgaaag
    22081 taacattcaa aaacagcatg taaatcagct cgacctaatt cccagtatgt ctgcatcata
    22141 ttgatttgat atagatccgt atgcagcgtc aaactgtcgt ctgggtaagt attattcatc
    22201 ttgtattact cctcttggca agttttcatt tcctacccat tataacaaaa aaaattaata
    22261 ggaaaagaaa tcttccattt tttctgaaaa agcacatgtt ttacggatat ttcttgctaa
    22321 aaatgaactc catctgctaa aactatcctt tcttattggt atttaaccta aacgagaaag
    22381 aatacttatt ttattcaatg tatccgagac acgaagaaat tagcgttttc tatttttctt
    22441 acttgataaa ataagtagat tttcctacta caatcgtagc cgttaagata ccgatgattg
    22501 aacaaatata accaaatgtc tctacaacat aatcaatggc aaaagttttt gaagcaataa
    22561 tacgtctttc cttttttgct tcttatcccc aaagaaacgg atataactta ttatgtattg
    22621 aatttttttg gaaaggcgaa ttatgacaag atataccttg cgttgaaaaa actcgcggaa
    22681 aaaatatcac acgtttttaa aaagatacaa agtaagaaag cagctgtcaa tagaatggaa
    22741 acaaaaatgg cgagacatca atcagtctcg ccttgttttt tattgtatac attagatatg
    22801 gagcaggtta ccataaagat gattattagt cgttattaaa tagaatcctt cgtatttttt
    22861 tgttctatca ctacaatatc tttatttgga cgtttgaatt gtattccggc acgttctagc
    22921 tcctgtttca ctcctacatg gactttgaca tcttctcgtg tcatttttaa aacgtgatga
    22981 atcgcatagt cgatttcttg ccttgtgatt tttttcttcg tattgatcat cacgacttgc
    23041 tttttatcat atgtgtctac caatagcagt tgtgttcgat ctaacgaaaa taatttgtaa
    23101 taattaatag ccgtattccc aaaaaagaat tccactactt taggataaaa tgtcttaata
    23161 tttaaattac tattcacagg tgtttcgatt agcttcatct cattcctctt ttctatatag
    23221 tcgatttaga tccaatctta agttatgtta ccatctttcc tagcattaag gaatcggtta
    23281 caattgaacc tttaaagaca aaaggattta ccttttatca cttaatagta taacataatt
    23341 tcgtgagaaa aaaatacaat tttttcttga ccatctcgtt acgtaaagga ttatgcttac
    23401 atttgtcagg aggaaaaata atggagtaca caataaagaa aatgtcagag atatcaggag
    23461 tcagtccgag aaccttgcgc ttttatgatg agattggact gctaaaacca gctaggatca
    23521 attcttcagg ttatcggatt tatggcaaaa aagaagtcga tcgtctgcaa cacatcttat
    23581 tttatcgaac aatggcattc aagttggatg atatccaaga ggtcttagac aatccatctt
    23641 ttgaccacca gaaagcttta atcaagcatc agcaaatgtt gctggaaaaa cgggcacaaa
    23701 tcgataccct cttgacaact gtccaacaga cacttgatat gtacgaagga ggaagaaaaa
    23761 tgagtgacaa agaaaaattt gaagggttta aacaacaaaa gttgaaagaa aatgaagaat
    23821 cctatggaca agagattcga caaaaatacg gaaaaaaaaa ggttacagca tccaatgaaa
    23881 aatggatgaa tatggataaa gaaacgtatg aagaaatgca aactgttgaa aagcagatgt
    23941 tatttgatct cactctttac ttaaaagaac cagaagatga aagcttagca gaccgtatct
    24001 tccaagctca taagaagtgg ttctcttaca gctggcctga atatcagcca aaagcgcata
    24061 aaggactagg aatgatgtac gaagccgatg aacggttcac tgcatattat gacgagcgaa
    24121 gtggtcatgg tgcagcaaaa gctttaaatg aaattatcca aaaaaaggcg taatctttta
    24181 catgatccaa caaaaaagta cacgtaaaat gacctaataa caaaacagca gacacccaag
    24241 ttagattttt atgctaactt ttggtgtctg ctccattctt tcacaagttt tttcatccta
    24301 ctttaaatat attcatcgtt gaataaacgt ataaggtatt ttcactttat cctttttttc
    24361 tgtaagaaac aattgaaatg ccatttctcc gcaagcttcc agatggtggt cgatggttgg
    24421 gaaaccaaga agctcgctga tcagcaaatt atcgcgtcca atcaccactg gtgtcttatc
    24481 ttgcagatag ctttgcaaga tgcctgctgc aaccatatcc gaatttgtaa agacaccatc
    24541 aactccaagc tctttaaaaa agaagcctgc ttgttttcct ttctctgcat ctatacaatc
    24601 ccaaaaaaca agtgattcat caaaagatgg aaaaagttga tgacatagct gcaaagtgat
    24661 ttttgagtta taacttagcc tgccacttcg ccccaacgtg atgcccaatt gctttatacc
    24721 ttgctgcttc aaataagtaa gaccttctgt aattgattgt tctcgatcaa taaagacaca
    24781 gcttgcctgt tttcccttga tttcttcaca aaaaactaga ggtccatatt tttgatatgc
    24841 caataaatca tctagtgtat tggcacgaga cgtaatgatc aatccatcga aagctttagc
    24901 tgcaaattct tcaagatacc ttcgctcttt ttctttatga tagcccgtcg gtaaaagtgt
    24961 cactttgtaa tcataatcaa acgctgcttc aatgatccca ctgatcaact gatcaaaata
    25021 cggatgattg gtataaggca gaatcactcc aatgcttttc gtttttccat aacttaactg
    25081 tctggcattt gcattaggga tataatcgac ttctttcatg accgcaagta tttctttcct
    25141 tttttcctca tctacatatg gatgtccatt gattacacgt gaaatagtag aaactgaata
    25201 acctgtgagc tttgcgatat ctcgaatgtt tgccactgct gcttcgccac ctatacaaaa
    25261 agattttctt gtaaatagtc taccacagct ggaccgcatt caaaaaactg atacattttt
    25321 ccttcatgcg aaaaactgat ccgctgcccg ccccaatata tatcttttgt caaattttcg
    25381 atttcattca ttggtatttc ttttactata ttcctattca acccttgaaa actgtacaac
    25441 gttaatacgg atcccttgaa ctcgacaaac gcataaaaat aattgttcgt tgtgccatct
    25501 gttatctcta cataagtatt cattgcaagc cctccttttg atactttgag tatagtgtat
    25561 gaaacgcgtc tcatagcaag gagtttgttt tgccaaagaa aagttttatt cctctttcat
    25621 tattaccaaa gtctcttatt ttaaattgaa tacattataa tgatactgta aatatatctt
    25681 tattattagt gaatg
//
LOCUS       DAFEIE010000037        23954 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFEIE010000037
VERSION     DAFEIE010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.038"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            172..516
                     /locus_tag="LP345_001704"
     CDS             172..516
                     /locus_tag="LP345_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBL1760486.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="LP345_001705"
                     /pseudo
     CDS             517..936
                     /locus_tag="LP345_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(1028..1378)
                     /locus_tag="LP345_001706"
     CDS             complement(1028..1378)
                     /locus_tag="LP345_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760487.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="LP345_001707"
     CDS             complement(1344..2675)
                     /locus_tag="LP345_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBL1760488.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVNN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="LP345_001708"
     CDS             2930..3496
                     /locus_tag="LP345_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1760489.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="LP345_001709"
     tRNA            3641..3728
                     /locus_tag="LP345_001709"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
     gene            complement(3835..4983)
                     /locus_tag="LP345_001710"
     CDS             complement(3835..4983)
                     /locus_tag="LP345_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1760490.1"
                     /translation="MATFEQYKKKNGEKLWKFQTYLGVDPLTGKQVRTTRRGFKTKKE
                     AQLALTKLQLEYESNGLNKSKELTFQEVYDLWIVNYEQTVKESSFVKTKEQFANHILP
                     AFGALKINKISIDIAQKFANEKVKKFVLYREFINNASRICDYAIKLGYLQDNPFKKIT
                     VPKRKVSVHEEDTLNFFNKEELEIFLKSVEKKKDIRMYSFFRTLAFTGMRVGELLALT
                     WKDIDFNDNYIKINKTLARGKNRRLYVEQPKTKNSKRDIPVDDETMNILKKWRLEQRK
                     WLLTLGINTLSKNQLVFSNQKNEYLQLSKPRKWLEVIIKQNNLKRITIHGLRHTHASL
                     LLEAGANIKDVQERLGHSSIQITMDLYIHITDKRKEKTAAQFAKYIGI"
     gene            complement(5081..5521)
                     /locus_tag="LP345_001711"
     CDS             complement(5081..5521)
                     /locus_tag="LP345_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760491.1"
                     /translation="MKFIKFGIIGLLAVTVMGGCGSSTAETKESKNYSETNSTIKEVD
                     SDQTAEFATIAEKHIKEIYSIDNLKMDLKSIKVTQFPDDKNAETGEEYKNVYNGTGDF
                     TWQDKKYNFSLIYSKKDATNYTVLYLYSNLDPNKGINTPLESDQ"
     gene            complement(5607..5807)
                     /locus_tag="LP345_001712"
     CDS             complement(5607..5807)
                     /locus_tag="LP345_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760492.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRTVKKSVIPSYGKKGSGWIKD
                     PKKAAYNKVYKRTSFSFWDLFK"
     gene            complement(5828..6667)
                     /locus_tag="LP345_001713"
     CDS             complement(5828..6667)
                     /locus_tag="LP345_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760493.1"
                     /translation="MPRKPLSEEDKKARSIIANNLKKITHGYTRAQLSDMTGIPVTTL
                     SGYFTEKSTISMENAELIAKAFNVDKSDIDPRYSREYNYYDLKKEVLDELQENNKSFV
                     ADKFVELAEKANAAGMTLNRTKTDRGNIMTVLSSDIQEYNFFDTSVAAGIPSSVEAFD
                     QDHIEQIAIPDYAMGKYAGYQDVFFTKINGDSMNNVIPDGSLIAVKKIESCDELKDGD
                     IVVFSNDNEFSVKRYINDQQNNRIIFRPDSSNISFTDIVVNYDDTKYVQIYGKVVVYI
                     VQL"
     gene            6833..7081
                     /locus_tag="LP345_001714"
     CDS             6833..7081
                     /locus_tag="LP345_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1760494.1"
                     /translation="MELQITLEAARVMMGYSLKEAAKLFDVHHQTLANWEQDPNKMKQ
                     KYVQLIPEIYHFPTANIFFGSKDEFIRYKLHNDSFLIK"
     gene            7124..7879
                     /locus_tag="LP345_001715"
     CDS             7124..7879
                     /locus_tag="LP345_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HBL1760495.1"
                     /translation="MKELIKVTTNEENEQLVNGRELHEFLEVATEYKKWFSRMAEYGF
                     VENIDFVRVTQKCPTPGGIQNITDHAMKLDMAKEISMIQRTEKGKQARQYFIEVEKEY
                     KQQLLDTSKLSPELQMFQGIFNAVAKQELETKRLATQMENITEIVALNTTDWRRECRK
                     LVNKMAETQGGYGAYQEIQTAIYEEVDRRAGSSLKTRLTNLRNRMAGEGVPKSKRDKT
                     NKLDVIESDKRLKEIYLSVVKDFAIKYGVWKEK"
     gene            7903..8163
                     /locus_tag="LP345_001716"
     CDS             7903..8163
                     /locus_tag="LP345_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1760496.1"
                     /translation="MEVILTPENEAALRSYIHEIITDEIAKARRDASVDKRVLKQIEI
                     AKYFGVSTATIRKWEDKGLPFGRIGDQKFYDKEKCRAWVLAQ"
     gene            8212..8388
                     /locus_tag="LP345_001717"
     CDS             8212..8388
                     /locus_tag="LP345_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760497.1"
                     /translation="MDKLNTTIVFSAPIIIYLLSVWGSKQALIGVIVYLVWMFAGLDE
                     AEYQTKKRHDRRQA"
     gene            8430..8759
                     /locus_tag="LP345_001718"
     CDS             8430..8759
                     /locus_tag="LP345_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760498.1"
                     /translation="MNKKIQNLIKKLAHECANDDLGMSVSVVDEKGEVALAQAGNDGL
                     VALSVYQQYEKTKYDLRKNNCNCETHSALRCMFDIDEEDAEFEEWCQEFLSFAEKMDR
                     KKGGIKF"
     gene            8759..8983
                     /locus_tag="LP345_001719"
     CDS             8759..8983
                     /locus_tag="LP345_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760499.1"
                     /translation="MISVKGLGDEIFEVMMNKAQQDIQEKILTAASYGQTSCTVCSKG
                     FTPSFLAALESEGVSNIQCEDGSVKLFWEF"
     gene            8993..9187
                     /locus_tag="LP345_001720"
     CDS             8993..9187
                     /locus_tag="LP345_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760500.1"
                     /translation="MKEFDSLGARQQLPNEASPVGVDWQGNPLYPGDTCYLTEEGYVP
                     VDAILEYVQQHYPKIELGGI"
     gene            9190..10212
                     /locus_tag="LP345_001721"
     CDS             9190..10212
                     /locus_tag="LP345_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBL1760501.1"
                     /translation="MANDLTQTTQRSLDEQVISNLGRLQEQGLEMPPGYSPQNALKSA
                     FFELTNNTGGNLLQMAANNQEMKTSISNALLDMVIQGLSPAKKQCYFIKYGNKVQLMR
                     SYFGTMAVLDRVAGGADITPVVVRQGDEFEVAMAGPNMVVQKHETKFENLDNEIVAAY
                     VVIKLANGKETTTVMTKKQIEQSWAKSKMKGSGPQKEFPEEMAKRTVINRAAKALINT
                     SNDNDLLVQAAKDTLENEFDNDRKDVTPQAEKVATLEQKFFSNKKIAEPIQKEPDPIV
                     IPDDIQNEVTRVADVPGHPEIEQAHLIENEDTDPIQEELLDVPDFGREEGADDVSEFE
                     DDEYPF"
     gene            10175..10990
                     /locus_tag="LP345_001722"
     CDS             10175..10990
                     /locus_tag="LP345_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HBL1760502.1"
                     /translation="MSQNLKTMSTLSNENYYSNEADWQYMSTSQYKSFLKCEAEALAK
                     LKGAWQPISDPKALLVGNYVHSYFESKEVHEAFKEENKSKMFSSRKPYGLLKDFQIAE
                     QMIDRLKQEEVFMNIYQGEKETIVTGELFGTTWKGKIDCLNLEEEYFVDIKTTKDMHE
                     RKWNENYGSRETFLVNFGYVLQMAIYQELLLQQYGKTFTPIIAAVSKQTPSEARLITI
                     EQDKMNYELVLLKEKIERIVRVKNGEEKPNHCGLCEYCRGNLPITGFTNMDDL"
     gene            11007..11792
                     /locus_tag="LP345_001723"
     CDS             11007..11792
                     /locus_tag="LP345_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760503.1"
                     /translation="MADKGWIALHRNIRDHWVYQEKRVFSKYEAWLDLLMDANHQNNK
                     FLFDGQLIEVNRGEFITSVRQLCERWGWSNTKVNRFLKMLEDDQMLIRKSDSKKTVIT
                     IVNYDFYQRYESKETTQKRQQNDAEASQKHTNNNDKTMNNNVNNNNPRTSRKKREYAD
                     DDPNKKLAILLLKLIRKNQNIKEPDLDKWANTIRLTIESDKRTGREVQDMIVWATSND
                     FWSGVILSPTSLRKHFDKMAIQKNKRKQQNISNDELPETGEDW"
     gene            11792..12640
                     /locus_tag="LP345_001724"
     CDS             11792..12640
                     /locus_tag="LP345_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1760504.1"
                     /translation="MDKKLSAMAAPYGGLKTADHNCPKCGDPLYIWKTKNKDGTDRCG
                     PTCINKICGYREMVTKNQKEAIQKANEAMKKDAINRMLNSSMITDDAIWTFDFDGYKV
                     VDQETAQIKGMAQEWAKKIVSGSTIHAVITGRTGAGKTHLGAAVIKEVMRASNYKIAC
                     SFISYRELLEQLKFAMNDPEARKAVTGSLMAEIKKTDFVVIDDLGAELGRMEENNQAT
                     PYDVDVLTSLTEARLNKATIFTTNLSSKQLKHAYGERVFSRVMNGTKGNIAVFKTTTD
                     KRRNPV"
     gene            12637..12879
                     /locus_tag="LP345_001725"
     CDS             12637..12879
                     /locus_tag="LP345_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760505.1"
                     /translation="MTFVVKKMCYLDSRGRGEASVEFAKHHTTKEEADLVASVCGGEV
                     VEVIKPKRRFSKPKTKPVKKECCCPKSNQAWMRGAK"
     gene            13022..13477
                     /locus_tag="LP345_001726"
     CDS             13022..13477
                     /locus_tag="LP345_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBL1760506.1"
                     /translation="MATRSKYGNKKHEVDGITFDSKAEARYYMKLKRNGMSFMPLSET
                     YCAMQENVLLQEGYLCNDRKIAPIYYRADFVIYENGQVKKVIDVKGYQDAISMLKMKM
                     FAHRYGFPVTFAKFDSKINKFIEMDCFESARQQRKRQTERRKKKLMEGK"
     gene            13479..14054
                     /locus_tag="LP345_001727"
     CDS             13479..14054
                     /locus_tag="LP345_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760507.1"
                     /translation="MTKQVNFRPELKKVTSKSNGNTEVLLVVSNGSLRGSTENLTEFL
                     GSTVTVVIQPETIEYTVPVNKQTKKPNIEYVVNSDGTIEMFKEEQTSLDIGDGVEEVE
                     NVTILVSKETVDDFIKTATTLQLPENVTVNIRDVLIRLDEGDSMNEIAADHELSETAL
                     IDQIELARQYFAPYADTWSKHKDDIIFPEEQ"
     gene            14051..14239
                     /locus_tag="LP345_001728"
     CDS             14051..14239
                     /locus_tag="LP345_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760508.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMDQ
                     KILDVGLLLLHLAEKNLI"
     gene            14250..14444
                     /locus_tag="LP345_001729"
     CDS             14250..14444
                     /locus_tag="LP345_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760509.1"
                     /translation="MIQLAGIQTGKIYFSGESKSEASQWLLKTFTNNKKLRKNYPNEF
                     LKDDQIMPEPMLLVRKKDNE"
     gene            14444..14761
                     /locus_tag="LP345_001730"
     CDS             14444..14761
                     /locus_tag="LP345_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBL1760510.1"
                     /translation="MDLINQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDQQTNWSQKLYQDRFKFVEKYREILEEYKE
                     DSK"
     gene            14758..15186
                     /locus_tag="LP345_001731"
     CDS             14758..15186
                     /locus_tag="LP345_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760511.1"
                     /translation="MIPKFRLYDPSDQKIREVAEIDWPLGIVGTCGGAIEHELDKVEL
                     MQSTTLKDKNGVEIFEGDIALITHKSTNYADTYWHSYVEVFRAKNGAYRIRGEHIYET
                     DLYSNRKQLTVAGNIYNSPELLKRDRFMTTTENPELLEVE"
     gene            15183..15521
                     /locus_tag="LP345_001732"
     CDS             15183..15521
                     /locus_tag="LP345_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760512.1"
                     /translation="MIILATDYIDSLKDEDGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSESAIKLFGAIEIYADDF
                     PNLWLKEEQR"
     gene            15518..16063
                     /locus_tag="LP345_001733"
     CDS             15518..16063
                     /locus_tag="LP345_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HBL1760513.1"
                     /translation="MNKQELIDRYTAEISRLRPYCPNRNQSEEKLKLGIFTEFIADLK
                     QLDESHKKIIPKCAHKFIQEGIDSGSDYFTIIICADSFANAKPQDEFSKWLRENSGLF
                     IRSLLNGYEVEKESLYYVVFDILQEQKFLVKNIKTKLFYLSNNENVIGNYEQVSFTEQ
                     EIKAIDERFWPFAVPVEEVTK"
     gene            complement(16163..16852)
                     /locus_tag="LP345_001734"
     CDS             complement(16163..16852)
                     /locus_tag="LP345_001734"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760514.1"
                     /translation="MKKCFFVTPIGTDDSPERKNSDTVLNHIIKPVCESVGFEVVRVD
                     QLHTVDRIDHTITEYLSNSDLVIVDLTYHNANVFYEFGYRQALGLPLIPLITEGESIP
                     FDVNTLRTIYYVINDLDKVENVKNKLLETIKHMTFETPQKPITNETNIDNTLLLNIID
                     KLEDIETAVQVRNDKETERIAELMSKYSHPQKSAEAEIFSSVFGPIMQMAAQDPNSLK
                     NISDAFGNVES"
     gene            17109..17588
                     /locus_tag="LP345_001735"
     CDS             17109..17588
                     /locus_tag="LP345_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760515.1"
                     /translation="MRFQWLKDYQELDEQILYLKWNLNKSKLELNRWVNGDLADVRIE
                     KNSRSASLEENIQKIENEIDLLEEQRKEMLAIINSFKGIDNEIIRKKYIEGCSLEIIA
                     EEIGYSASYVRQRHAEIRKTLDFLDEYEQNKLSRESKLGEIDYYNNRREDTEQISLF"
     gene            17848..18195
                     /locus_tag="LP345_001736"
     CDS             17848..18195
                     /locus_tag="LP345_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760516.1"
                     /translation="MNDFHEAVLTFDVPAGMGQVYKKAIEDDNSRHWIKNEIKDSNGN
                     IVISDIKPVWNGNYCNVDITDGVRGHSNLTITLLSRTLPNLQEQVDWYKRMGAKVIST
                     NYKGENQNGNEKN"
     gene            18176..18562
                     /locus_tag="LP345_001737"
     CDS             18176..18562
                     /locus_tag="LP345_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760517.1"
                     /translation="MVMRKIRSSITGTEYWDSEKKKTVVVPKGQEPDFEATEEKGILS
                     DGKTFVAVNGELITNSSEILDSAGNTAADFDEDEATNDKSAEEADELDNMTAKELRAY
                     AKKHGIDIPSAIRAKGDILKFIREAE"
     gene            18559..18939
                     /locus_tag="LP345_001738"
     CDS             18559..18939
                     /locus_tag="LP345_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL1760518.1"
                     /translation="MKYCQFDGCTNKIAKGIYCAEHKRSSKSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            19050..19502
                     /locus_tag="LP345_001739"
     CDS             19050..19502
                     /locus_tag="LP345_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBL1760519.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMRKSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKVKTGRQITGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            19499..21226
                     /locus_tag="LP345_001740"
     CDS             19499..21226
                     /locus_tag="LP345_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL1760520.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYRWKKRKDIW
                     FDVNRANEMMDWVETFIVHTKGEMVGKPFLLESWEKFIYSWIYGWVKENEKGQTVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAATILN
                     NPILLEGTKIFKGPKGTVSSITYDYIHKDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MDLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            21290..22477
                     /locus_tag="LP345_001741"
     CDS             21290..22477
                     /locus_tag="LP345_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1760521.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLKILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQGTPETEAVYISNDLTEIGKKHATDDSLPTNNQNLKGGDENVEEGD
                     SNN"
     gene            22449..23018
                     /locus_tag="LP345_001742"
     CDS             22449..23018
                     /locus_tag="LP345_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBL1760522.1"
                     /translation="MSKKEIRTIDITDLSTRSNEETQTRTISGYAAVFNSPTRLWEDL
                     DEVIAPGAFSRAVSSSDVRCLFNHDWSNVLGRTKSGTLRLSEDERGLKFEVDLPDTTV
                     ARDLIKSMERGDINQCSFGFMPTEETWDYNSTPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSKEDLEKIVEKRKNLIKKINQALEA"
     gene            23031..>23954
                     /locus_tag="LP345_001743"
     CDS             23031..>23954
                     /locus_tag="LP345_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL1760523.1"
                     /translation="MNKELLKKLKARQEQRLEELRGKIESGELREADIEGVQQEIDAV
                     IEELNGIKDALSDNSDPGNAGDGKDGGAGNGTDDPDTRSSDEPSGDGADKGEGGEDDP
                     ENRAGMITQQQRDGLLGSIKNGLEARAKMTKEQKEQQIRKAFANFVVGNISEAEARAL
                     GIETGNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKK
                     ERSTDITETAIQFDEILLDPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEI
                     NYMFNGDDAGNENPGALAKKAVAFEKPLDLTA"
BASE COUNT         8576 a         3752 c         4763 g         6863 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggtaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaacttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat aatagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttattgacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tataacattt cataatagag gcgaaaacat tgatatacag gcatttgctt
     3781 gcaatgtttt cgcctctgtt tttttgtttg aatacgtctt tgaatacgtt ctgcttaaat
     3841 accgatatat tttgcgaatt gcgctgctgt tttttctttt cgtttgtctg taatgtggat
     3901 atataaatcc atagtgattt gaatagacga gtggcctaaa cgttcttgta cgtccttaat
     3961 atttgcacca gcttctaaaa gtaaactagc atgtgtatgt ctaagaccat gaatagtaat
     4021 acgtttaaga ttattttgtt tgataatcac ttctaaccat ttacgaggct tagataattg
     4081 gagatattcg tttttctggt tagaaaatac cagttgattt ttgcttaacg tattaattcc
     4141 caatgttaac aaccattttc tttgttctaa tcgccatttc ttcaagatgt tcatagtttc
     4201 atcatcgact ggtatatctc gcttagaatt tttggtttta ggttgctcta cataaaggcg
     4261 tctatttttt cctctggcga gagttttatt tatcttgata taattatcgt taaaatcaat
     4321 gtctttccat gtgagagcta agagctcgcc tacgcgcatc cctgtgaagg ctagtgtccg
     4381 aaaaaaagaa tacatacgaa tatctttttt cttttctact gatttcaaaa agatttctag
     4441 ttcttcttta ttaaaaaagt ttaaagtatc ttcttcatga acagagacct ttctttttgg
     4501 aactgtgatt tttttaaaag gattatcttg tagatatcct aatttaatag cataatcaca
     4561 tatacgcgaa gcattattga tgaattctct atacaacaca aattttttta ccttttcatt
     4621 agcgaacttt tgagctatat caatcgatat tttattgatt ttaagagcac caaatgctgg
     4681 taatatatga ttcgcaaact gttcttttgt tttaacgaaa gaactttctt ttactgtttg
     4741 ctcataattt acaatccata gatcgtatac ttcttgaaaa gttaactctt tagacttatt
     4801 tagaccatta ctttcgtatt ccaattgtaa tttggtcagc gctaattgag cttctttttt
     4861 tgttttaaaa cctcttcgtg tagttctcac ttgtttgcca gtcaaaggat ctactcccaa
     4921 ataagtttga aacttccaca atttttcacc gtttttcttt ttgtattgtt cgaatgttgc
     4981 catttttttc gtcctttcgc tcgggtaagt gttcggacta aaatagctgg catcacctcc
     5041 ttagttatac gcttgctttg ggctggtagg cgtttatatt ttattgatca ctttctaatg
     5101 gtgtatttat acctttatta gggtctaaat tactatatag atataggaca gtgtaattag
     5161 tcgcatcttt ttttgagtaa atcaaagaaa agttgtattt tttgtcttgc caagtaaaat
     5221 ctccagtacc attgtagaca tttttgtact cttcaccagt ttctgcattt ttatcgtcag
     5281 gaaattgagt aactttgata gattttaaat ccatcttcaa attatctatc gaatatattt
     5341 ctttaatgtg tttttcggca atagttgcaa attcagcagt ttgatcagag tctacttctt
     5401 tgatagtact gtttgtctca ctataatttt ttgattcctt tgtttcagct gttgatgatc
     5461 cacatcctcc cataactgtc actgctaata atccaataat tccaaattta ataaatttca
     5521 ttttctactc cttatctcta tggtattatt ttattggaga atcttagaaa taaggtttct
     5581 agtccgtgtg ccagcacggg ctttttttat ttaaataaat cccaaaaact aaacgaagtt
     5641 ctcttgtaaa ctttgttgta agcagccttt ttgggatctt tgatccatcc cgaacccttt
     5701 ttcccataac taggaataac tgattttttt acagtacgtt ttgctttacc agttgttcta
     5761 gcgctgatag atttctttat gctcggtttt ctcattccaa ttttcatttt ataccctctc
     5821 aaattaatta tagttggaca atatatacaa cgactttccc ataaatttga acgtatttag
     5881 tatcatcata attaaccaca atatcagtga aagaaatgtt agaagaatca ggtctaaaaa
     5941 tgatgcgatt attttgttga tcatttatat atctttttac agaaaattcg ttatcgttgc
     6001 taaagactac tatatctcca tcttttaact catcacagct ctctattttc tttacagcaa
     6061 ttaatgatcc atcaggaata acgttattca tggaatctcc atttatttta gtaaaaaata
     6121 catcttgata tcctgcatat tttcccatgg cataatcagg aatagcaatt tgctcaatat
     6181 ggtcttgatc aaaagcttcg actgaagaag gtatgccggc agcaacagaa gtgtcaaaaa
     6241 agttatattc ttgaatatca cttgatagaa ctgtcataat gtttcctcta tcagttttag
     6301 ttctgttcaa agtcatccct gctgcatttg ctttttctgc taactctaca aatttatcag
     6361 caacgaaact tttattgttt tcctgtaatt catctaaaac ttctttcttt aaatcataat
     6421 aattgtattc tctggaatat cttggatcta tatcagattt atcaacatta aaagctttag
     6481 ctattaattc agcgttttcc atactgatag ttgatttttc agtaaaatat cccgatagcg
     6541 tcgtaacagg aatacctgtc atatctgaca attgtgctct tgtgtagcca tgcgtaattt
     6601 tttttaaatt gttagcgata atggagcgag cttttttatc ttcttctgat aatggttttc
     6661 ttggcatgtt attttctcct ccttttttat taataatatc gaattaaatc aacataaaca
     6721 agtataaagt agttttataa cagtgttttt taatttaaaa aacgtcaaaa atcgttgact
     6781 ggtagtataa actagtataa aataatttac ataaacgaaa ggaggaataa aaatggaatt
     6841 acaaattact ttggaagcag ctagagttat gatgggatat tctttaaaag aagcagcaaa
     6901 actctttgat gttcaccatc aaaccttagc aaattgggaa caagatccga ataaaatgaa
     6961 gcaaaaatat gtgcaattaa taccagaaat ataccatttt ccaacagcaa atattttttt
     7021 tggaagcaaa gacgagttta tacgatataa acttcataac gattcatttt taataaaata
     7081 acttatgaaa aacgtattta ttcattttta aggagtgtaa tccatgaaag aactaatcaa
     7141 agtaacaaca aatgaggaga atgagcagtt agtaaacggc agagaattgc atgagttttt
     7201 ggaggtggca acagaataca aaaaatggtt tagtcgtatg gcggaatatg gttttgttga
     7261 aaatatagat ttcgtaaggg tgacccaaaa atgtccgacc cctggaggaa ttcagaatat
     7321 taccgaccat gcaatgaaat tggacatggc aaaagaaatc tcaatgattc aacgaacaga
     7381 aaaaggaaaa caagcgcgtc aatattttat tgaagtagaa aaagaataca aacaacaatt
     7441 acttgatact tcaaagctaa gtccagaact tcaaatgttc caaggaatat ttaacgcagt
     7501 agctaagcaa gagttagaga caaaacgtct agcaacacaa atggagaata ttactgaaat
     7561 tgtggcattg aatacaactg actggcgtag agaatgtcga aagctcgtaa ataaaatggc
     7621 ggaaactcaa ggcggatacg gtgcttatca agaaattcaa acagcgatat atgaagaagt
     7681 tgatcgtaga gctggctcct ctctcaaaac tagattaacc aatttacgta accgtatggc
     7741 tggcgaaggt gttccaaaat ccaagcgaga taagacaaat aagttagatg taatcgaaag
     7801 tgataaaagg ttaaaagaaa tttatctatc tgtagtcaag gatttcgcta ttaagtatgg
     7861 agtttggaaa gaaaaataaa attcgatagg aggttcagga ttatggaagt aatcttaacg
     7921 cctgaaaatg aggcagcact tcgtagctac attcatgaaa tcataactga tgaaattgca
     7981 aaagcaagaa gagatgcctc agttgataaa cgtgtattaa agcaaataga gatagcgaaa
     8041 tacttcggag tatcaactgc aactattcgt aagtgggaag ataaaggact tccattcggg
     8101 cgtataggcg atcaaaaatt ttacgacaaa gaaaaatgta gagcatgggt tctagcacaa
     8161 taaaatatcg ggtaagtgtt cggaaataat gacagtaaag aaggggaatt tatggacaaa
     8221 ctaaatacaa caatcgtatt cagtgcgcca atcattattt atctgctgag tgtctgggga
     8281 agtaaacaag ctttgatcgg ggtaattgtc tacctcgttt ggatgttcgc agggttagat
     8341 gaagctgaat atcaaactaa aaaaagacac gaccgccggc aagcatagtc gtgtcaaaag
     8401 aaataagcta tcaaggagag tttatcacaa tgaataaaaa aatccaaaat ttaatcaaaa
     8461 agttagcgca tgaatgtgcg aatgatgatc taggaatgtc agttagtgta gtcgatgaaa
     8521 aaggggaagt tgctcttgct caagctggaa acgatggctt ggttgcatta agtgtttacc
     8581 aacaatatga aaaaacaaaa tatgacttgc ggaagaataa ttgcaattgc gaaactcaca
     8641 gtgctttaag atgtatgttt gacattgacg aagaagatgc tgagtttgag gaatggtgcc
     8701 aggaatttct tagttttgcg gagaaaatgg accgcaagaa aggtggtatc aaattctgat
     8761 gatctcagtt aaaggactag gcgatgaaat attcgaagta atgatgaata aagcgcaaca
     8821 agatatccaa gaaaaaatct tgactgcagc aagctatgga caaacgagtt gcactgtttg
     8881 ttcaaaagga tttacaccat catttctagc agcactagaa agcgaaggtg tttcaaatat
     8941 ccaatgtgaa gatggaagtg tcaaattatt ttgggaattt taggtgatca cgatgaaaga
     9001 atttgattct ttaggtgcca gacagcaact accaaatgaa gctagtcctg tcggagttga
     9061 ttggcaagga aatccgttgt atccaggtga tacttgctat ttaacagaag aaggctatgt
     9121 accagtagac gcaattctag agtatgtcca gcaacattat ccaaagattg aattaggagg
     9181 aatttaggaa tggcaaatga tttaacacaa acaacacaac gttcattaga tgagcaggtg
     9241 attagtaatc ttggacggtt acaagaacaa ggcttagaaa tgccaccagg atatagtcca
     9301 caaaatgcgt taaagagtgc ttttttcgaa cttactaaca atacaggtgg aaatttgcta
     9361 cagatggctg caaacaatca agaaatgaaa acctccattt ctaatgcact tttagacatg
     9421 gttatccaag ggttatctcc agcaaaaaaa caatgctatt tcattaaata cggaaacaag
     9481 gttcaactaa tgcgttcata ttttggaaca atggcggtcc ttgatcgtgt agctggaggg
     9541 gcagatatta cgcctgtagt cgttcgacaa ggtgatgagt ttgaagttgc aatggctgga
     9601 ccaaacatgg ttgtccaaaa gcatgaaaca aaattcgaga atttagacaa tgaaatcgtt
     9661 gctgcctatg tagtcatcaa gttagcaaat ggtaaagaga ccacaacagt catgacgaaa
     9721 aagcaaattg agcaaagctg ggcgaagtca aaaatgaaag gttccggacc gcaaaaggaa
     9781 tttccagaag aaatggctaa acggacagta atcaatcggg cagctaaagc attaattaac
     9841 acaagtaacg acaacgattt attagttcaa gctgcaaaag atacgttaga aaatgaattt
     9901 gacaatgatc ggaaagatgt aacgccacaa gcagaaaaag tggctactct cgaacaaaaa
     9961 ttcttttcaa acaaaaagat tgctgaacca atacaaaaag aaccagatcc gattgtgatt
    10021 ccagatgata tccaaaatga agtaactaga gttgctgacg tacctggtca tccagaaata
    10081 gaacaagcac atttaatcga aaatgaggat accgatccga ttcaagaaga attattagat
    10141 gttccagatt tcggacgtga ggaaggtgca gatgatgtct cagaatttga agacgatgag
    10201 taccctttct aatgagaatt attactcaaa tgaagctgac tggcagtaca tgtcaacatc
    10261 acaatataag tcctttttaa aatgtgaagc cgaagcattg gccaagctca aaggcgcttg
    10321 gcagccgata tctgatccta aagctctttt agtcggaaac tacgtacatt cttattttga
    10381 gtcaaaagaa gtacatgaag cgttcaaaga agagaataaa tccaaaatgt tttctagtcg
    10441 aaagccttat ggattattga aagatttcca gattgctgaa cagatgattg atcgactaaa
    10501 acaggaagaa gttttcatga acatttatca aggtgagaaa gaaacgattg taaccggtga
    10561 actgtttggg acgacatgga aaggcaaaat tgactgctta aatttagaag aagaatactt
    10621 tgtcgacatc aaaacaacga aagacatgca cgaacgtaaa tggaatgaaa attatggatc
    10681 aagagaaaca tttctagtca attttggata tgtacttcaa atggctatat atcaggagtt
    10741 acttttacag caatacggaa agacgtttac accgatcatt gcagctgttt ctaaacaaac
    10801 accaagtgaa gctaggctta taacaattga acaagacaaa atgaattacg aacttgtctt
    10861 attaaaagaa aaaattgagc gaattgtcag agtgaagaat ggtgaagaga agccgaacca
    10921 ttgcggttta tgcgagtact gtaggggtaa tcttccaata actggattca ctaatatgga
    10981 cgatttatag aacggtgggt gagtagatgg cagacaaagg ctggatagca cttcaccgaa
    11041 atatccgaga tcactgggta tatcaagaaa aaagagtttt ctctaaatac gaagcgtggc
    11101 tagatttgct gatggatgcc aatcaccaga ataataaatt tttatttgac ggccaactaa
    11161 tagaggtaaa tcgtggggaa tttattacat cagtaagaca gctatgtgaa agatggggtt
    11221 ggtcaaacac caaagtaaat cggtttttaa aaatgttgga agatgatcaa atgttgattc
    11281 gaaaaagcga cagtaaaaaa actgttataa ccattgtcaa ttatgacttt tatcaacgtt
    11341 acgaatctaa agaaacgaca cagaaacgac agcaaaacga cgcagaagca tcacagaaac
    11401 acacaaacaa caatgataaa acaatgaata acaatgtaaa caataataat cctcgtacct
    11461 ctcgaaaaaa acgagagtac gcagatgatg atccaaataa aaaattagcc attcttttat
    11521 taaaactcat tcgaaaaaat caaaacatca aggaacctga tttggataaa tgggcgaata
    11581 cgattcgttt aacaattgaa tctgacaaac gaactggtag agaagttcaa gacatgattg
    11641 tgtgggctac tagtaatgat ttctggtctg gagtgatttt atcaccgact agcttaagaa
    11701 agcatttcga taagatggct atccaaaaaa ataaaagaaa gcaacaaaat atttctaatg
    11761 atgagttacc agaaacaggt gaggattggt aatggataaa aaactaagtg caatggctgc
    11821 accttatggc ggattaaaaa cagcagatca taattgtccg aaatgtggtg atccattgta
    11881 tatctggaaa acaaaaaata aagatggtac tgatcgttgc ggtcctacat gtatcaataa
    11941 gatttgtggt tatcgagaaa tggtaactaa aaatcaaaaa gaagctatcc aaaaagcgaa
    12001 tgaagcaatg aaaaaggacg ctatcaatcg aatgcttaac agttcaatga ttacagatga
    12061 tgccatatgg acctttgatt ttgatggata caaagtagtc gatcaggaaa cagcacaaat
    12121 aaaaggaatg gctcaagaat gggctaaaaa aatcgtaagt ggtagcacga ttcacgcggt
    12181 tattactggt agaacaggag ctggaaaaac tcatttaggt gctgcagtga tcaaagaagt
    12241 gatgagggca tctaattata aaattgcctg ttcatttata agctaccgag aattattaga
    12301 gcaattgaag tttgcaatga atgatccaga agcaagaaaa gctgtgacag gatcgttgat
    12361 ggctgaaata aaaaagacag attttgtggt gattgatgat ttaggtgcgg agctaggtcg
    12421 aatggaagaa aacaatcaag caacgccata cgatgtcgat gttctcacat cactcacaga
    12481 agctcgtcta aacaaagcta cgatattcac gaccaattta tcatcaaagc aattaaaaca
    12541 cgcatacggc gagcgagtgt tctctcgtgt aatgaacggg acaaaaggaa acatagccgt
    12601 attcaaaaca acaacagaca aaaggaggaa tccagtttga cctttgtagt gaaaaaaatg
    12661 tgctacttag atagccgagg acgaggagaa gccagtgtcg agtttgctaa acaccacacg
    12721 actaaagaag aggctgacct tgttgcaagt gtttgtggcg gcgaagtagt cgaagttatt
    12781 aaacccaaaa gacgattttc aaaacctaag accaagccag tgaaaaaaga gtgttgttgt
    12841 ccgaaaagta accaagcatg gatgagaggt gcaaaatgac ttgtttaaaa tgcaacgatg
    12901 aaacagttat ttggtataag acatcacttg gatggtcaac ctgtgaacct tgtccaatat
    12961 gcaatgacaa tggacgacgt tcgaaagaaa gactcgaaag actaaagaag gagcatagca
    13021 aatggcaaca agaagcaaat acggaaacaa aaagcacgaa gtagacggca tcacttttga
    13081 ttctaaagca gaagctcgtt attacatgaa gttaaaacga aacggtatga gttttatgcc
    13141 attatctgaa acttactgtg ccatgcaaga aaatgttctg ctgcaagaag ggtatctatg
    13201 caatgatcgt aagattgcac cgatttatta tcgagctgat tttgtgattt atgagaatgg
    13261 ccaagtgaaa aaagtgattg atgtcaaagg ttatcaagat gcaatctcta tgctcaaaat
    13321 gaagatgttt gctcatcgat atggctttcc agtgacattt gctaagtttg attcaaaaat
    13381 caataagttt attgaaatgg actgctttga atcagcaaga cagcagcgga aaagacaaac
    13441 ggaacgaaga aaaaagaaat taatggaggg aaaataaaat gacaaaacag gtgaatttca
    13501 gaccagaatt aaagaaagta acatcaaaat caaatgggaa cacagaagta ttactagttg
    13561 ttagcaacgg atcattgaga ggtagtactg aaaatttaac tgaatttctt ggctcaactg
    13621 tgactgtagt aattcaacca gaaacaatcg aatacacagt accagtaaat aagcaaacga
    13681 agaaaccaaa tattgaatat gttgtgaatt cagatggcac aatcgaaatg ttcaaagaag
    13741 agcagacttc acttgatatc ggcgatggtg tagaagaagt tgagaatgta acaatcctag
    13801 tatcaaaaga aactgttgat gattttatta aaacagcaac aacattacaa ctaccagaaa
    13861 atgtcaccgt aaatattcga gacgttctta tccgtttaga tgaaggcgat agtatgaatg
    13921 aaattgctgc agatcatgaa ttatcagaga ctgctttaat tgatcaaatc gaattagcta
    13981 gacaatactt tgctccatat gcagatacct ggtccaaaca taaggatgac atcatttttc
    14041 cagaggaaca atgagagcaa ctgatccagt aattatcctt gaggaagcca aatttatttg
    14101 gactcacgaa gagatagagc aagcacgctt gctcttttct caaggagtta agccgagcaa
    14161 agtagctgaa ataatggatc agaagattct tgatgtcgga ttgcttttgc tccatttagc
    14221 agaaaaaaat ttgatttgag gtgaaattga tgattcaact tgcaggcata caaacaggaa
    14281 aaatttattt ttctggagaa agtaagagtg aggccagtca gtggttgctt aaaacattta
    14341 ccaataataa aaagttacga aaaaattatc caaatgaatt tttgaaagat gatcagatta
    14401 tgcctgagcc aatgttatta gttcgaaaga aagacaacga ataatggatc ttattaatca
    14461 atacagtgac atcatcctca agaaaatcat gatgaagatt cagaaagata aaaaatcaaa
    14521 agaacgagct gaattagtta agttagaaat ggctgaaaca ggagcaggag tgcgaagtag
    14581 caggcattgg aaagcagcag caaacattga attttattat aacgaaattc aaaaaggatt
    14641 cgatcagatg cgtgagttgg atcagcaaac aaattggagc cagaaactat accaagatcg
    14701 ttttaagttt gtagaaaagt atagagagat actagaggaa tacaaggagg acagcaaatg
    14761 ataccgaagt ttagattata tgatccatca gatcaaaaaa ttcgagaagt tgcagagatt
    14821 gattggcctt taggaatagt tgggacttgt ggtggagcga ttgaacacga attagataaa
    14881 gtcgaactca tgcaatctac cactctgaaa gataagaatg gtgtggagat atttgaaggg
    14941 gatatagcgc ttatcactca taaatcaacg aactacgccg acacttattg gcacagttac
    15001 gtagaagttt ttagagcaaa aaatggagcc tacagaattc gcggtgaaca catctacgaa
    15061 acagatttat atagtaatag aaaacaattg acggtagcgg gaaatattta taattcacca
    15121 gaacttttga agagagatcg atttatgact actactgaaa atccagagtt attggaggta
    15181 gagtgattat cttagctact gactacatcg attctttaaa agatgaagat gggaatgtcc
    15241 cagcattgct aaattgtgga attaaaagta agaatagaat cattttgtta cggatatcgg
    15301 ctgatttagc aaaatatctt tatctgagca agacagcagt atattacact gcggctacac
    15361 gttatcagta caagggaaaa acaatcagtc aggattatta tgatcgttta atcagtcctg
    15421 acatgcatgg aaaatcagaa tcagcgatca agttatttgg cgcaatagag atatatgccg
    15481 atgattttcc aaatttatgg ttgaaggagg aacagcgatg aataaacagg aattgattga
    15541 tagatatact gcagaaatat ctagattaag accttattgt cctaatagaa atcaaagtga
    15601 agagaaactt aaattaggta tttttacaga attcattgct gatttaaagc aactagacga
    15661 atctcataag aaaatcatac ctaaatgtgc acataagttt attcaagagg gaatagattc
    15721 agggtcagat tattttacaa ttattatttg cgctgattcc tttgctaatg cgaaaccgca
    15781 agatgaattc tcgaaatggt taagagaaaa tagtggtttg ttcattaggt cattactaaa
    15841 cggctacgag gtcgagaaag agtccttgta ttacgtagta tttgatattt tgcaggaaca
    15901 gaaattttta gtgaaaaaca ttaaaacaaa attattttat ttatcaaata atgaaaatgt
    15961 tataggtaac tacgagcaag taagttttac cgaacaagaa atcaaagcaa tagatgagag
    16021 attctggccg tttgctgtgc cagtggaaga ggtgacgaaa tgactagaac attattatta
    16081 attgcaggga tattaataaa agaattgaaa aaacaacagt cccttgtagc atattacaaa
    16141 ggactgtacg aaggcgaaaa acttaagact caacattgcc aaaagcatca ctgatatttt
    16201 ttaacgagtt gggatcctgt gctgccattt gcattatagg accaaataca ctgctaaata
    16261 tttctgcttc tgcggatttt tgaggatgag aatacttgga cataagttca gcaattcttt
    16321 ctgtttcttt atcgtttcta acttgaacag cagtttctat atcttcaagt ttatcaataa
    16381 tgtttaatag taaagtgtta tcaatatttg tttcattagt tattggtttt tgaggagttt
    16441 cgaatgtcat atgttttatt gtttccaata atttattttt cacattttct actttatcta
    16501 aatcatttat aacatagtag atagttctaa gtgtatttac gtcaaatggg atactttctc
    16561 cttcagttat cagtggtatt aaaggcaacc ctaatgcttg cctgtaacca aattcataaa
    16621 aaacattagc attatgataa gttaaatcga caatcacgag gtcagagtta gataagtact
    16681 ctgtaatagt atgatcaatt ctgtcaacag tatgtagttg atctacacga actacttcaa
    16741 aacctacact ttcacatact ggctttatga tgtgattgag aaccgtgtcg gagttttttc
    16801 tttcaggaga atcatcagtt cctatcggag tgacaaaaaa acattttttc ataaaataac
    16861 ctcatttcat tttttattag attatatcaa ataatagtaa tgatagtatt taaaaatcta
    16921 agaataattt ttatgtgttt aacgtgaatc attacatgga ttgatggtat tagaaattaa
    16981 ggcttagatg aataagtaaa aagcgaataa attatgtttt cgggatccat aattattcgg
    17041 gaaataaaaa agccacctct ttcgagatag cagcgcaata ctattttatc atataagggg
    17101 tggcgtttgt gagatttcag tggttaaaag attatcaaga acttgatgag cagattcttt
    17161 acttaaagtg gaatcttaat aaaagtaagc ttgaattgaa tcgatgggtc aatggggatt
    17221 tagcagacgt ccgcatcgaa aagaattcta gatcagcttc tttagaagaa aatattcaaa
    17281 agatagaaaa tgaaattgat ttactcgaag aacaaagaaa agaaatgctt gctattatta
    17341 attcttttaa agggattgat aatgagatta ttcggaagaa atatattgag ggttgttcat
    17401 tagagataat agccgaagag attggctaca gcgcatctta tgtcagacaa agacacgcag
    17461 aaattcgtaa aactttagac ttcttagatg agtatgaaca aaataaactg agtagagaaa
    17521 gtaaattagg cgagattgat tattacaaca atcgtagaga agatactgaa cagatcagtt
    17581 tgttttaaaa ttacaatgtt cactaaatgt tcgaacattg tagctatgta aacattgttt
    17641 gcagcatgat attctattag tgtcaaaaaa atatgaaaga gccaagatat cccaaattgg
    17701 tatctgtggc tcttttctat tgctttgatt ggacagtagc aaatacaaaa aataaaaaca
    17761 tcttcttatt atctttcgat agctactgtc tagtacataa aggatcactc gttgagtggt
    17821 ctttttattt tgaaaggagt tttatctatg aatgattttc atgaggctgt acttactttt
    17881 gatgttccag cgggtatggg gcaagtttat aaaaaagcaa ttgaagatga taacagtagg
    17941 cattggatta aaaacgaaat taaagatagc aatggaaata ttgtgatcag cgatatcaag
    18001 ccagtatgga atggtaatta ttgcaatgtt gatattactg atggagtacg cggtcattcg
    18061 aatttaacta tcacattgct ttctagaaca ttgccaaact tacaagagca ggttgattgg
    18121 tataaacgta tgggtgcaaa agtaatcagt acaaattaca aaggagagaa tcaaaatggt
    18181 aatgagaaaa attagatcat caattactgg aacggagtat tgggattcag aaaagaaaaa
    18241 gactgttgtg gttccgaaag gtcaagaacc tgattttgaa gcaacggaag aaaaaggaat
    18301 cttaagcgat ggtaaaacgt ttgtggctgt taatggtgaa cttattacta atagcagtga
    18361 aattcttgat agcgctggaa acaccgctgc tgattttgat gaagacgaag ctactaatga
    18421 taagtccgct gaagaagcgg atgaactgga caacatgact gcaaaagaat tgcgtgcata
    18481 tgctaagaaa catggtattg atattcctag cgctatccgt gcaaaaggcg acatcctaaa
    18541 gtttatccgt gaagcagaat gaaatattgt cagtttgatg gatgcacgaa caagatagca
    18601 aaggggatct attgtgccga acacaagcga tcaagtaaat cgcgcaagaa gaagcaacaa
    18661 gcaaagtctg tttatcatca tgagaacaaa ccattctatc gaacacaggc atggaaggac
    18721 atgcgtcaat ttatttatga aagagaaggt ggacactgtc agcgatgcgg tcagttcatc
    18781 ttcggcaaga gggcacatgt ccatcacatt gtacccatca aagacaatga actgcttaag
    18841 cttgatccaa acaatctcat gcttttatgt tcaaaatgtc atccaattgt tgaaaatgaa
    18901 acggaagaca aaaaagtttt cccttcgtat ttcaattgaa gcccccctat ccattttcaa
    18961 aattttttcg cgtggggaga tagggtagcg gggagtcacg cgcatcgtta ggtcaaattt
    19021 ttcaaaaaca aaggggggtg tataaaaaaa tgacgactaa agcgcaacgt aaagcgatta
    19081 ttgatgaaaa agtaagtgct gaaaaagctc gtatcttaga aataatgcgt aagtctgatt
    19141 tgtacactat cactcttgat ccgcttattg aatcatatct ggatattttt gaaatatacc
    19201 aacataaata tttattgtgg aaagaaaaag gttttccaga aactcaaaaa ttcacgaata
    19261 aatcaggtgc tactaatcaa tcaaaacatc cgttagcgca acaagtagaa acttgggcag
    19321 ataagaagat gaaagctctg gatttattag gattaacgaa caaagtaaaa actggtagac
    19381 aaattactgg aggatcgact gcaagaaaag atgaagaaat tacacgtccg gaagtaaaac
    19441 cagtagatga actagcagcg cacagaaata aatggcgtaa gaaggcaggt gctgaaaaat
    19501 gattgaacct ggtgtaaatt atgctgattt atttgcaaaa gaagtaagaa agaaacctaa
    19561 gaagtatcct aaaaccgttc gtttagcaat agatcgttgg tataggtgga aaaaaagaaa
    19621 agacatttgg tttgatgtaa atcgggcgaa tgaaatgatg gattgggtag aaacatttat
    19681 tgttcacaca aaaggagaaa tggtaggaaa accatttctt ttagaatcct gggaaaaatt
    19741 tatttattct tggatttatg gttgggttaa agaaaatgaa aaaggacaaa ctgttcgcgt
    19801 tactcgtgag gcttatgttc aaatcccaaa aaagaatggt aaaacattga ttgccgtagg
    19861 ttcattaggt tatgcaatgt acggtgaagg tgctttatca gtcgattgtt atgcgtgcgc
    19921 ctctgatttt gctcaagctc aatatgctgc taaacctttt gcggctacca tcttaaacaa
    19981 tccaattcta cttgaaggaa caaaaatatt taaaggacca aagggaactg tttctagtat
    20041 cacttatgat tatattcata aagatatggc ttactcgaat aaatttattg ttcaaacgaa
    20101 gaatattgat aacattgagg gttcaaatcc atattttgtg ttgaatgatg aattgcataa
    20161 gcaagagaaa atggaacagt atgacaattt taagtctgct caaatatctt taccacagcc
    20221 attgatgttt aatatctcaa ctgctgggaa aggttcgtcg tctgttggaa tgcgtgtata
    20281 tcgcgaagca aaagaagtgt tgaaacgcga tgataatgat tcaaactttg ttctaatcta
    20341 tgagccaaat aaaaattatg attggacgga tagaaaagtc tgggaaatgt gcaatcctaa
    20401 ctggggaata tcagtcgatt tatctgcttt agaatcggca tttaaaacag cgcaacggtc
    20461 agctcattcc aaagctgaat ttctaacgaa acacttggat gtatttgtga acggcgcgga
    20521 taatttcttt gaacaggatc aagtagagcc atgtttagtt accacacaag aacttggtga
    20581 tttaagtggc gaaccatgtt atatcggttt agatttatca cgtacacgag atttgacctg
    20641 tgtatcttta aacttcccaa catgggatga agatggtaaa gcggttctta aagtaaagca
    20701 actctatttt attccgaatg aagatttaga gtttcgagaa aaagaagata atgttcctta
    20761 cagtgatttg gctgaacaag gtttcgttga attttgcgat ggaaaaatga ttgatcaaga
    20821 tcagattttg cagtacatag aggactgcat ggatttatat gatattcagc aagtaaatta
    20881 tgatccagca atgagcgata aacttgttga gaaactagaa aacttaggat tggaatgcgt
    20941 tgaggttgcc caatatccta aagtattgaa tgcacctttt gatgatgtcg agcggttgtt
    21001 ttatgagaaa cggattcaat ttgataaccc attattccta tattgcactt taaacgttgt
    21061 agcaattact aacatcaatg gacaaaaagc gccaagtaaa cgccaatcaa agaaaaagat
    21121 tgatgggttc gtggcgtttt tgtgcggtca taaggaaacg atgaatcaaa tgacagatat
    21181 tgattcggat gagttagatg attatctaag ttccatttat agataaatag aaaggcggtg
    21241 agaaaaattg aaattacgtg atcggttatc gaatgcagtt tattctttta tggaaaaacg
    21301 tggatatatc gaggatattt ttggacacta cacacgttat ggtcaaagat atgtgacgga
    21361 ttcatctatc atggaatctt ctgatgttta tgaattagtt caagacatat ccaatcaggt
    21421 ggcattggcc acaccgattg ttattggtcc tgatggcaac gaagtcaaag atcatcactt
    21481 gctaaagatt ttgaagagtc caaatgatta tttgaccgga ttcgaattta ctaaattgga
    21541 aacaaatact ttattgatca atggtgagac attcccatta acggataggg atcagctcca
    21601 tttggcgtac ggtgtaacaa ctaagatcaa tgaacgactt caagaagaat ttgaaatgaa
    21661 tggtcaaaaa atacctggtc aaatgattcg acacattaag aacatcggaa ctgattcatt
    21721 aaaaggtgct ggaataattg atcttgcaag aaacactctg gaaggcgttc tgagcgctga
    21781 aaaagttttg acggataaat atactaaagg cggtttactt gcgttcatgc ttaaactaga
    21841 cgcccacatc aatccaaata atagcgccca aacaaaaatt gtcaaagcta tattggatca
    21901 actggaagga acgcaaaatg agagtgatca ttctgttaag atgattcctt tgggaaaagg
    21961 atattccatc gagacattaa aaagtcctgt tgatgatgca gcaattttga actatttagg
    22021 tgtttacaaa aaagacttag gaaaatttct aggaatcaat gttgatacgt atcaatcgct
    22081 gatgaagaca gatattgaaa aagcgatgat gtatctgcac aacaaagcaa tcaaaccaat
    22141 attgaaaaac aagagcgaac attacaccgc tctttttttt atgcctaatt ctggctatag
    22201 agtggaatgg aaaattaata ttttggattt tgttccttac tcaacaaaaa caaatattgg
    22261 ctacaacatc gttcgtactg ggattacaag tccggataat gtggcagaaa tgcttggttt
    22321 ccctaaacaa ggaacgccag aaactgaagc tgtttatata tcaaatgatt tgacagaaat
    22381 cggcaagaag catgcaacag acgattcttt gcctacgaat aaccaaaact tgaagggggg
    22441 tgatgagaat gtcgaagaag gagattcgaa caattgacat caccgatctc tcaacacgtt
    22501 ctaacgaaga aacacaaaca agaacgatta gtggttatgc agcagttttt aatagtccaa
    22561 caagattatg ggaagactta gacgaagtga tagcacctgg tgctttttca agagctgtta
    22621 gcagttccga tgttcgatgt cttttcaatc atgattggtc caatgtttta ggacgtacaa
    22681 aaagcggcac gctacgttta tcagaagatg aacgtgggtt gaaatttgaa gttgatcttc
    22741 cagatacaac agttgctagg gatttgatca aatcgatgga acgtggcgat atcaatcaat
    22801 gcagttttgg attcatgcca actgaagaaa catgggatta caactctaca ccaatgctta
    22861 gaacaattca cgaagtggaa ttgtatgaag tttctatcgt gccgttacca gcgtatgaag
    22921 ataccgaagc agctttaaga agcaaggaag acttagaaaa aatagtcgaa aaaagaaaaa
    22981 atttaattaa aaaaatcaat caagcgctag aagcttagga ggaaatcatt atgaataaag
    23041 aattattaaa gaaattgaaa gcacgtcaag agcaaagatt agaagagtta cgtggaaaaa
    23101 tcgaatctgg tgaattacgg gaagcagaca tcgaaggcgt tcaacaagaa attgatgcag
    23161 tcattgaaga attaaatgga atcaaagatg cgttgtcaga taatagtgat cctggtaatg
    23221 caggagatgg gaaagatggt ggtgcaggaa atggcactga tgaccctgac actcgttcta
    23281 gtgatgaacc tagtggagat ggcgctgata aaggagaagg tggagaagat gatcctgaaa
    23341 atcgcgcagg tatgattacc caacaacaac gagatggatt acttggatca attaagaacg
    23401 gattggaggc acgtgcaaaa atgaccaaag aacaaaaaga acaacaaatc cgaaaagcat
    23461 ttgctaattt tgttgttgga aatatttctg aagcagaagc tcgagcttta ggaattgaaa
    23521 ccggcaatgg ttcagttact gttccagaag taattgcatc tgaagtcatc acttatgctc
    23581 aagaagaaaa cttacttcgt aaatatggaa cagtggtgcg aacatcagga gatgtcaaat
    23641 atccaattct tgtgaagaaa gcagatgcga atgtaaacaa gaaagagcgt tcaactgata
    23701 ttactgaaac agctattcag tttgatgaaa ttttgcttga tcctgccgaa ttcgatgctt
    23761 tggcaacagt aactaaaaaa ttactaaaaa tgtctggtgt tccagttgaa gatattgttg
    23821 tggaagaatt gaaaaaagct tatgtgcgta aagaaatcaa ttatatgttc aatggtgatg
    23881 acgctggaaa tgaaaatcct ggtgcattag ccaaaaaggc tgtagcattt gaaaaacctt
    23941 tagatctaac tgct
//
LOCUS       DAFEIE010000038        23571 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFEIE010000038
VERSION     DAFEIE010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.039"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="LP345_001744"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="LP345_001744"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBL1760524.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="LP345_001745"
     CDS             complement(1172..1867)
                     /locus_tag="LP345_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBL1760525.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="LP345_001746"
     CDS             complement(1880..2596)
                     /locus_tag="LP345_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBL1760526.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="LP345_001747"
     CDS             2926..3531
                     /locus_tag="LP345_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBL1760527.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="LP345_001748"
     CDS             3856..4179
                     /locus_tag="LP345_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBL1760528.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="LP345_001749"
     CDS             4361..5731
                     /locus_tag="LP345_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBL1760529.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="LP345_001750"
     CDS             complement(5861..7162)
                     /locus_tag="LP345_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL1760530.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9350)
                     /locus_tag="LP345_001751"
     CDS             complement(7392..9350)
                     /locus_tag="LP345_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBL1760531.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="LP345_001752"
     CDS             complement(9527..9793)
                     /locus_tag="LP345_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1760532.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="LP345_001753"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="LP345_001753"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBL1760533.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="LP345_001754"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="LP345_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBL1760534.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /locus_tag="LP345_001755"
     CDS             13137..13700
                     /locus_tag="LP345_001755"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL1760535.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="LP345_001756"
     CDS             complement(13953..14474)
                     /locus_tag="LP345_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBL1760536.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="LP345_001757"
     CDS             complement(14477..15319)
                     /locus_tag="LP345_001757"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBL1760537.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="LP345_001758"
     CDS             complement(15312..16037)
                     /locus_tag="LP345_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBL1760538.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="LP345_001759"
     CDS             16213..16509
                     /locus_tag="LP345_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760539.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17077..18669
                     /locus_tag="LP345_001760"
     CDS             17077..18669
                     /locus_tag="LP345_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1760540.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="LP345_001761"
     CDS             18682..19422
                     /locus_tag="LP345_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1760541.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19590..20939
                     /locus_tag="LP345_001762"
     CDS             19590..20939
                     /locus_tag="LP345_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1760542.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21067..21657)
                     /locus_tag="LP345_001763"
     CDS             complement(21067..21657)
                     /locus_tag="LP345_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL1760543.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21804..23156
                     /gene="brnQ"
                     /locus_tag="LP345_001764"
     CDS             21804..23156
                     /gene="brnQ"
                     /locus_tag="LP345_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL1760544.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6750 a         4746 c         4490 g         7585 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac tctcttaata tggaagtaat
    19561 taaacttttt tagttaggat gatttaaaaa tgaatgaaga gcaagaactg cagcgtggac
    19621 tgaaaaatag acatgtccaa ctgatttcta ttggcggagc gattggaacg gggttgtttt
    19681 taggttccgg aaagtctatc cagctagctg gcccttcgat attgctcgcc tatcttatta
    19741 ctggatgcat ctgttttttc attatgcgtg cgttaggcga acttctgtta tcaaacacca
    19801 ataaccattc ttttctggat tttgttgcag aatatcttgg caaaaaagcg gctttcatca
    19861 ctggctggac gtattggttc tgctgggtat cgattgcaat ggccgattta acagccatcg
    19921 gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg gcttcctgaa ctgattgcat
    19981 taggtcttct tctttgcttg aatatggtgg ctgtctcatt gtttggtgag ttagagtttt
    20041 ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat cctcgtagga gcttatatga
    20101 tcctcaccca ctatacgaca gatattggca cagccagtat cacgaatcta tggtctcatg
    20161 gcggattctt tccaactggt gcaaaaggat ttatcttagc tttccaaatg gtaacctttg
    20221 cttttgctgg gatagaatta gttggattag tcgctggaga aacagaaaat cctgaaaaag
    20281 tgttgccgga agctatcaat aatattccta tcaggatcat cttattttac ttaggatctc
    20341 tttttgtcat tatggcaatc tatccatgga acagcttgaa tccagataac agtccatttg
    20401 tagaagtatt ttcggaaatt gggatcacga ttgctgcttc cttgatcaat ttagtcgtat
    20461 taagtgcagc agcttctgcc tgcaacagtg caatatatag tacaggacgt atgcttcgtt
    20521 ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa gttaacaaca catcatgtgc
    20581 cagggaatgc tttgacattt tctactatcg tcattttcat ttctgttatc ttgaattacg
    20641 tgatgcctag tgaagtattc acactagtaa gcagtattgc cactacttgt ttcttgttta
    20701 tctggagtat gcttgtctac acgcacatga aatatcgtaa aagtatcctc ggcaaaaaag
    20761 ctcattcatt taaaatgccg ttgtacccat ttagtaatta tctggtattt ctttacatgg
    20821 cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag aatcgcttta ttactaacac
    20881 ctgtgtggtt cttgcttcta ttactaatct atcatatgaa atatgaacgt aagaagtaag
    20941 aaagtagttg tgacagaagt ggtcagcttc gagaaataag aaggaattta cgaaaattgc
    21001 ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga taaaagcttc tgtcccagcc
    21061 tcttttctat ttccccggaa acaaccgctg ataataggca tctgcttttt tataggaaaa
    21121 aatccaaata ccagatacaa aaaaacgtcc gaataacccg atcaacggta caaaaaagac
    21181 accggcaatc aagcataagt taatcatcat ggagataaga cttcgacggt cctttgacaa
    21241 aactctcacg acatgggaat ctggtttatt tgctttcatg atttgcctca tcaagatacc
    21301 aaaagaaaaa ctccacatcg tgtatactaa gacataagcc atctcaggcc aaaaagcttc
    21361 agggttacgc ccgacccaac tagtaacaga aggacataaa gtcagccaaa agagcaaaaa
    21421 gatattcgac cagaccactc ggtaattaat tcgttctgcc atctgaaata tacgatgatg
    21481 gttcacccag atcaccgcaa caaatataaa gctgatggta taagctaata atgtatttcg
    21541 gatgacccat aaagaatgaa agctagatgt attagggatc ttgatctcta atacaataac
    21601 tctcaaaaca atggctacca ctccatcagt aaatgcttct aatctcgact ttgtcacgat
    21661 gattcctcct cagatgattc agcgctttta ttttatcact tacgttatta aataaccatc
    21721 gttttatata gggaattttc tgaaaattgt tgcatatttt tcgaaatttt gttactttta
    21781 aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc atttaaagac tatcttttta
    21841 taggctccat gcttttcggt ctattttttg gtgctggaaa tcttatcttt cccgttcatt
    21901 tgggtcaaga agcaggcgct gctacctttt gggcgaatct aggtttcttg gttaccggta
    21961 tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc gaaaagctca ggtgtatatg
    22021 aattagcaaa acggataaat caaacatatg cgatggtttt taccatcttg ctttacttag
    22081 ttatcggacc gttttttgct ttacctcgcc ttgcaaccac atctttcgag attggtttag
    22141 caccatttat cgatcctagc agacagacgc tatatctagc aattttcagt attgtatttt
    22201 ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat attagattat gttggaaagt
    22261 tcctgaatcc tgcatttttg gttttattag gtgctttgct tctccttgct tttttgaatc
    22321 cactaggttc tgtaaatcaa gcgcctattc agccaaatta tcaagagcat gcttttttca
    22381 cagggtttac tcaaggatat aacacattag atgcgcttgc tgctttagca tttgggatca
    22441 tcattgtcac aacaatccaa aacatgggtg taacaaaacc tgctgaaatc gctaaagaca
    22501 cgatcaaatc tggtgcgatc agcattatat tgatgggaat catttatact ttgctcgctt
    22561 atttaggtgc tatgagctta ggtagctttg ctctaagtga aaatggcggg atcacgctgg
    22621 ctcagattgc tgatcattat ttaggtactt atggcagtat cttattagca tttatcgtta
    22681 tattagcttg cttgaagacc ggtattggtt tgattacagc ttttgcagaa acattcacag
    22741 atttgtttcc gcaaagaaat tacgcattct ttgttgcact tgctagtatc cttccttgtt
    22801 tagcggcaaa cgtaggcttg acgaatatca ttcaattttc gttgcctgtt ttgatgttca
    22861 tctatccatt agcaatgaca ctgattttac tagtgttagt tggtcctttg tttaagcagc
    22921 gtacggctgt ttatcgaatg actacttatt ttacattgat tgcttcgatt tttgatgggt
    22981 tgaacgcttg cccagaaact atcaaacaaa cacctattgt tcaaaatctt ttatatgttg
    23041 cggaaagcta cttgccgttt ttcaaattgg ggatggggtg gatcgtacca gcagttatcg
    23101 gttttgttat cggactgatt tggagtttcg ctaagaaaga agaagtagca gattgataaa
    23161 agaggttgtg aaagagacgt tcagccttga gcaataaaaa gtaattttga aaaatggctt
    23221 ctcacatttt tgcataaatt tgacttaata ccgagaaact gacttttgaa caccgtttat
    23281 tgagaggtcg tgaaaaagcc gcttagtttc aagtattaag aaatattttg tgaaaatggc
    23341 ttctcacatt tttgcataaa tttgacttaa taccgagaaa ctggcttttg aacaccgttt
    23401 attgagcgtc tataaactga cctgagtatt agagaaacaa aacggcaaag tagctccata
    23461 tactttgccg ttttgttttg aactaatacc gaagagaagc tgatcaaaca acatttcttt
    23521 tataatatag attttagaca tatatatgat ataaaaatag ttttcgcaaa a
//
LOCUS       DAFEIE010000039        22924 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFEIE010000039
VERSION     DAFEIE010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.040"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(172..1404)
                     /locus_tag="LP345_001765"
     CDS             complement(172..1404)
                     /locus_tag="LP345_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBL1760545.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1659..2228
                     /locus_tag="LP345_001766"
     CDS             1659..2228
                     /locus_tag="LP345_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1760546.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2406..2846)
                     /locus_tag="LP345_001767"
     CDS             complement(2406..2846)
                     /locus_tag="LP345_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBL1760547.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3004..3768
                     /gene="map"
                     /locus_tag="LP345_001768"
     CDS             3004..3768
                     /gene="map"
                     /locus_tag="LP345_001768"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBL1760548.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3800..4723
                     /locus_tag="LP345_001769"
     CDS             3800..4723
                     /locus_tag="LP345_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBL1760549.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4799..5938
                     /locus_tag="LP345_001770"
     CDS             4799..5938
                     /locus_tag="LP345_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBL1760550.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5931..6731
                     /locus_tag="LP345_001771"
     CDS             5931..6731
                     /locus_tag="LP345_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1760551.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6731..7558
                     /locus_tag="LP345_001772"
     CDS             6731..7558
                     /locus_tag="LP345_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1760552.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7536..8270
                     /locus_tag="LP345_001773"
     CDS             7536..8270
                     /locus_tag="LP345_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1760553.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8370..9236
                     /gene="rfbA"
                     /locus_tag="LP345_001774"
     CDS             8370..9236
                     /gene="rfbA"
                     /locus_tag="LP345_001774"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBL1760554.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9250..9822
                     /gene="rfbC"
                     /locus_tag="LP345_001775"
     CDS             9250..9822
                     /gene="rfbC"
                     /locus_tag="LP345_001775"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBL1760555.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9844..10872
                     /gene="rfbB"
                     /locus_tag="LP345_001776"
     CDS             9844..10872
                     /gene="rfbB"
                     /locus_tag="LP345_001776"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBL1760556.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10970..11821
                     /gene="rfbD"
                     /locus_tag="LP345_001777"
     CDS             10970..11821
                     /gene="rfbD"
                     /locus_tag="LP345_001777"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBL1760557.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11855..13888
                     /locus_tag="LP345_001778"
     CDS             11855..13888
                     /locus_tag="LP345_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760558.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13932..15211
                     /locus_tag="LP345_001779"
                     /pseudo
     CDS             13932..15211
                     /locus_tag="LP345_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            15421..16227
                     /locus_tag="LP345_001780"
     CDS             15421..16227
                     /locus_tag="LP345_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760559.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16239..17459
                     /locus_tag="LP345_001781"
     CDS             16239..17459
                     /locus_tag="LP345_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760560.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17449..19035
                     /locus_tag="LP345_001782"
     CDS             17449..19035
                     /locus_tag="LP345_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1760561.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19074..21212
                     /locus_tag="LP345_001783"
     CDS             19074..21212
                     /locus_tag="LP345_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1760562.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21580..22563)
                     /locus_tag="LP345_001784"
     CDS             complement(21580..22563)
                     /locus_tag="LP345_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBL1760563.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         7195 a         3910 c         4727 g         7092 t
ORIGIN      
        1 ggttcacaac gcaaaacatt gtgcttttga tgaggttgaa cttttacaca agattgtgga
       61 cttgactaaa aaaacggtgg ggttgtttag cgaaataaag gatctaagcc aatagcttag
      121 atcctttatt ctatgcttta tattattttt tgcatgtgtg cgaaagtata ctcaagccca
      181 atcgccattt cggaaaatcg gtactgtaga gccatcttca cggattccgt cgatatccat
      241 cttgtcagat cctaccatga aatctacgtg ggtttgactt ctattcaatc cagcttctgc
      301 taattcttca tcggacattt ctgtaccgcc tttcacactg aaggcataag cagaacctag
      361 tgctaagtga ttcgatgcgt tttcatcaaa taatgtattg aaaaagatga tgccagattg
      421 agaaataggt gaagggtcag gtacaagtgc gacttctcct aaacgacgcg caccttcatc
      481 tgtatcaagc agttttgcta agacatcttc tccttgttcg gcagaaaaat caacaacttt
      541 tccatcttta aaagtaaatt tcatacccga gatgatggtg ccagcataac tcagtggctt
      601 tgtacttgaa atgtaaccat ctactcgatg actgtcaggt gctgtgaaca cttcttccgt
      661 cggcatattt gccatgaatt tttctccacg agcattatag cttccagcgc cttcccagag
      721 atggttttta ggcaatccga taatgatatc tgtaccggga gcagtatagt gaagggcaga
      781 aaattgttct cgattcaatt cttctgcttt ttttgctaat ttttcatcat gcttcttcca
      841 tgctaagaca gggtcttctt catagacacg agtcgttttg aaaatctgat cccataatgc
      901 ctcaacttgt ttttcttctg gcagttctgg gaagactttt gctgcccatt gtttaccagc
      961 cgcagccacg acagtccaac tgactttatt tgcttgagtt gccttgcgta aattcattag
     1021 tgctttgcca ttcgctgatt gataagacgc tactcgatgg ctatctacac cagcaaatgc
     1081 atcgggatcg gcagaaacaa cgctgatcct gcttgctcct ttttcaagcc attcatccgc
     1141 ttgatcgatt ttagattgtg gtacattctc aatacgatcc gttgcagcat gtaaaagaaa
     1201 ttctctttgg atctggtcgt cagtccattg aacgataacc tcagcggctc ctagtttata
     1261 agcttcttgt gtgatcaatc gagcaagggg tgcctgttcc acgctgatct gtaaaacaac
     1321 tgtgtgtcct ttttctgtgg ctacgccagt ttctgcaatt aagcgtgcat atttttttag
     1381 aagttcatta aaatcagata acataataaa aattcctcct caccattttt tctggtaact
     1441 attagcatga taccatttaa ttatgattca aacaatgagg ctttaaataa aaaaaggagg
     1501 ttattttttt aaggttaagt ttcatgatat atgttactac ttgctatttc agcttgtgaa
     1561 gaaaatcaaa aactaatttt gcatatcaaa aaaaacatgt tacaatgaaa ttaatcaatg
     1621 gtggaagcgt tataaaaaaa ttaaggagat taaaaaatat ggcaagaaaa aagacgatta
     1681 ctagagaaca gattttggca gctgcttatg aagtagctgc caccgatgga tttacacgat
     1741 ttactgcgag aaacatcgcg aacaaaatga attgttccac gcaaccgatt tatcttgagt
     1801 ttaaaaatat ggatgacttg agacaagctc tttttgagca gatctatgat catttacaat
     1861 atgaagtgtt cactgttgag catacaggga atacgattat cgatcttgct tttaattata
     1921 tccattttgc aagaagagag aagaagttgt atcgttcact gtacttagaa gaatatggtg
     1981 gaggaaaaga gatgcagaat ttctcttata cttactttgt gaatacagtg aaacgcgatc
     2041 cagcttatgt gaatctttca gaagagcaga tcgaatcttt gtataatggg acatggatca
     2101 tagctactgg gatcgcagct ttgatgtctt caagcatcat ccatccaact gatgaacaga
     2161 ttgaaaagat gatccaagac agtatagatg ctatcttgaa attcaaagaa ccaatcgaaa
     2221 tcgattgaat atactcaaaa gttccacaaa tcagtaggta acaagagatg tgtcaaaata
     2281 aggaaaagtt cgtttttctt acagcgtatg catttttaac tcccgaagaa ctcttccatg
     2341 aatgcaatga ataaaagagc catacagatt gaataaatct ggatggctct tttattgcaa
     2401 gtatattaaa tttttgcgac tagttcttta gcgaaagctt ctaaattttc gatatcttct
     2461 tcttcagcat tcagatccac tttaacattt tcggctcctt ttgatgcgcc tgtttttgca
     2521 aaagcagcat cgaaatcatc caccgatttg cagaattcat cgtaaaaagt atcaccagat
     2581 ccgcagacac cgtaaatttt tcccaataga tccaattctt gcaagtcttc ataaaagtct
     2641 acgatctcat caggcagatc gccatcatcg tatgtataag tagctactac gcaaatatct
     2701 gcctcctcga attcatctgc atctacttgg gtacattcgt tgatttcgac ttcgatatcc
     2761 agattttcaa atgcttctgc aacaatatcg gcgatttctt cagtgtttcc tgtcatgcta
     2821 gcatatacga tttttgctaa agccatgatg tgcctcctcg tttataatta tttaacaatt
     2881 atgaattata ccaaaacatc attgaaaaga aaataaaacc tagagacacc tggggaatgt
     2941 catttggcta aatgtatgcc gctatgttaa aatgagaggg atttgtaaaa aggagacgaa
     3001 aatatgatta ctttaaaatc agcacgtgaa attgaaatga tggcagaatc tggagcttta
     3061 ttagcagatg tacataaaaa tctgcgtgat tttataaaac caggaatcac aagttgggat
     3121 attgaggtat ttgtcagaaa ctatatcgag agtcatggcg gaattgctgc gcaaattggc
     3181 tttgaagggt atgaatatgc gacttgtatc agtataaatg atgaaatttg tcatggattc
     3241 cctcgtaaaa agcctttgaa aaacggtgat ttggtaaaag tcgatatgtg tatcgatttg
     3301 aaaggcggca tttctgattc ttgttgggcc tatgtagttg gagaatctac acctgagatc
     3361 gaccgattga tggaagtaac gaagaaagct ttgtacatcg gtattgagca agcacaagta
     3421 gggaatcgga ttggtgacat cggtcatgct atccaaactt atgtagaagg cgaaaatcta
     3481 gcgatcgttc gtgattttat tggtcatggc gttggtccta cgattcatga agaaccagca
     3541 gttcctcatt acggagaagc tggaaaaggg ttgcggttga aagaaggcat ggttatcacg
     3601 atcgaaccta tggttaatac cggaacttgg aaaatgaaaa tggatcctaa cggctggact
     3661 gcgtatacaa gagacggcgg actttcttgc caatatgaac atacattggc tattactaaa
     3721 gatggtccaa gaattttgac atcacaagga gaagaaggca cttattgatc tatccagtca
     3781 ataggtacgg gagaggtaca tgaaagtttg gaacaaaata aaacaaaatg aaaatctgat
     3841 gcgctttatt gagacgactc aaaagcgcat cactgattca gaaatgagta cgacctctgt
     3901 cgtcgttgct tattatttac tcttgtcttt atttccattg attattgctt ttggtaatat
     3961 tttaccgttt ctccacatcg atcaagagac tgtactgacc tatttacgag aagtgattcc
     4021 tgagaccgtt taccagttta tcggtcctgc aatcaaagac cttttgacac aaagttcagg
     4081 aggcttgtta tccgtttctg cattagcggc tttatggtct gcaagtcaaa gtatcaatgc
     4141 tttgcaaatt gcgatgaata aagcgtatgg cgtagaaaat agaaaaaatt ttttgatcgt
     4201 ccgtttcttc tcactaattg tcattgtctt gttcatgatt gctattagtg gggtaactat
     4261 cgttcttggg ttgggacagc tgattttgga tgctattcag ccaatcgtac aaatacccgt
     4321 gaactttatc gatcagttcc aaactttgaa gtggccaatc acattggtag ctttatttgt
     4381 catcatgttc ttgatttatt taattgtccc taatgctcag ttgaagttga agacgatcat
     4441 tccgggcacg atcttcgcta ctgtcggctg gatgctgtta tcacaagtgt ttagtatcta
     4501 tgctaggtat tttgcaacga ggatcagcgg ttatcagatc ataggaagtt ttattgtact
     4561 catgctttgg cttaattttg ctgctacgat catcattttg ggcggaatca tcaatgcagt
     4621 tgttcaagaa tacgtgacgg gtcatcaaat caaaaaacgt cgagatccaa gccgaaaatg
     4681 gttcaataaa ttgaaaacta aattttctca taaaaaaaag tagaaacaag agttcttatt
     4741 gtaaatttat atcagtaatt tataataatt atgactctta attaaagtag gtgcccatat
     4801 gcttgtttct tttagtatgg ttataagatt ttttctgaca attttattat cactgatatt
     4861 aacacctgta ttcaaaatca tttcagtaca aacaggtatg gtcgacaaac caaatgaaag
     4921 aagaataaat aaagttccaa tgccttcagc gggcggactg cctatcttta tttcatttgt
     4981 tatatcgact ttattcttat tccgtaaaat tatccctcaa tcgtatattg taccgatctt
     5041 gattgcttct ttagtaatca tagtcacagg agtgctcgat gataaatatg agctgacacc
     5101 taaacaaaaa agtataggga tcttgattgc ttctcttatt atttattttg tagcagatat
     5161 acgtattgat tccttcacgc ttccttttat tggatatatc caactaggct ggcttagttt
     5221 tcccgtaacg attttttgga tcttcggtat cacgaatgcg gtcaatctga ttgacggttt
     5281 ggatgggctg gcggcaggga tttcattgat cggtttaatt acgataggaa tcattggata
     5341 ttttttcctc catgcttcta cagtgtatat tccagttgtt attttctgtc ttgtagcaag
     5401 tattatcggt ttttttcctt acaattttta tccggcaaag atttatttag gcgatacagg
     5461 agctctattc ctagggttta tgatggccgt cctttcacta caagggctga agaacgtgac
     5521 ttttgtttca tcgatttctt tgctgatcgt catgggagtg ccggtaacag acacgttttt
     5581 tgctatcatt aggagaaaag caaaccgtgt ttctttttct acagcagata aaaaacatct
     5641 tcatcaccga ctaatcagtt taggctttac tcataaaggt gctgtcctga cgatttatgc
     5701 gatggctttg atgttttctt tcacagctat ggtcatgaat tatactggaa gaatcggaac
     5761 gatcatattg attattgcca tgttgtttgc tgcaatttta ttatttgaat tgattggtct
     5821 gatcaatgag aaacatcagt ttattttaaa aacattgcga tttttaggga ataaagagta
     5881 ccgtacgcaa gtaaaacaga aatatttgaa gaaatggaac cgtcatatag atgaataaca
     5941 aattaaacca gccgatcctt attagtattg tgacggcaaa cagtgataaa atttttcgga
     6001 cactagataa ttttatttca actgtaaaag atgaaacagc agtaaaaatc cgaatttttg
     6061 acaacaattc acttcccgag tacaaaaaaa gactaacaga gtataggaaa tatccctaca
     6121 tcgatatcta ttttcatgat gaaaattccg gatttggtta tggacataat cacaatctga
     6181 tagctagcga ttctcgctat ggcattattt gtaacccaga tattttagtg gatgaagaga
     6241 cagttacagc attggtcttg ttattgaaag aacatccgga atgtgcgatg ttagcaccta
     6301 agattcttaa tgaagatgga acaactcagc acctcatccg tgagcagctg gctgtttttg
     6361 attacgtttt gcgctttgtg cctttcaaat gggtcaaaaa aaagtttgac aaacgactgg
     6421 ctgtgtttga atgccgagga ttgcctactg atgctaatag ttatgtacgg atgatctcag
     6481 gtagttttat ggtagctgat attgataaat ttaaagagat aaaggggttt gatgagcgtt
     6541 tcttcatgta ctttgaagac aacgacttgt gtttgagttt tgaaaaagca ggttacaagt
     6601 tattgtacac acccttttat gcagttatcc atttttacgg gaagggtgcg catcgaaatg
     6661 caaaactgtt tcgcgtgttt ttgacttcta tgatgaaatt tttcaataag tgggggtggc
     6721 gttttttctg atgaaaccag aaatattagt agtcgttgtg ctttatcagc aactattcag
     6781 tcaatctcca gcttatggac cattaagcaa agcacttagc gaaaagcaaa ttcagcttat
     6841 tatttacgat aatagtcctc aaaggcagca aaatgagctg tttgaaaaag aaaatatcgt
     6901 ttatcatcat gatccgcaaa atcctggttt agcggtggct tataattttg cgttgtctca
     6961 agcagatgaa ggaacacgtt gtctcgtcac tctggatcag gatacgaggc tagtcgacga
     7021 ttattttgaa ctattgcgta aagtaacctt tacagatgaa tgtgttgctg cagttccgat
     7081 gattttttct gggagccgac aagtttctcc cctatattca gatcgttata tcaatcgtac
     7141 agctcaagca gtagaagttg aaggcccaac agctgaacga atcatggcaa tcaattcagg
     7201 tgttgcctgg tctgtcaaat ttctaaaaaa gattggcggg tttaatcctg ctttttcttt
     7261 agattttttg gatcattggc tgttttggaa agtggatcag ttggaaaaaa ctgtggagat
     7321 ccttcctgta cgaatggaac atgatctttc ggttttagac tatgaaaaag tttcaagtaa
     7381 tcgataccgt tctattttac aagcagaaaa tcgattttat catgaatatg atcaaaggca
     7441 tttatccagt caccgacgac aattattgtt aagaacagct aaacagttct tgaccgtcaa
     7501 aaaccggcat atctggcgga tgactttgcg ctcatatgtt aagaattgga aggtgtgaat
     7561 tcgtgcgttc ggtttgtata gctaccttta atggaggcag atatttaaga gagcagttag
     7621 atagtatttt atctcagctt tcagcagaag atgaagtagt catttctgat gatgggtcag
     7681 tagatgatac atgggatata ttaactgaat acgcagaaaa agataagcga atccagcttt
     7741 tttcggggcc tcgtcaagga ttgatcgcta attttggtta tgcgatccag cagacgaaag
     7801 gagatctaat ctttttggca gaccaagatg atgtttggtt ggagacaaaa gtgaaaaaga
     7861 tcactgacta ttttgagcag aatccggatc agctagtagt agtttctgat ttaatcattg
     7921 tggacagcga gctgcaagag atccatgatt cgtatttttc gtttcgaaat tccaaagaag
     7981 gatggcttaa taatgtgata agaagtcact atattggtgc tggtatggct ttccggtctt
     8041 ctttaaaacc cgatattttg ccgatcccgt cagaagtgcc gatgcatgat atgtggattg
     8101 gtttgctggg aggaaagaag actgggttcc taagagaacc gttaactctg taccgaagac
     8161 atgatttaaa cgcgagtgag attgaaacac attctaaatt acggcaaaaa atttcttggc
     8221 gtgttcatct gattacggcg ttgatcaaac gaaaatggtt taaacgttga taaaagatgt
     8281 ttaaatcctt aatatttcca tgacaaatat aacaattgat gagataataa caaagtgaaa
     8341 tttgaaatca aaaaggagag cagatatcca tgaagggaat cattcttgct gggggcagcg
     8401 gaacacgtct gtacccttta acaaaggcaa catcgaaaca attgatgccg atttatgaca
     8461 aaccaatgat ttattatcca atgtctactc tgatgttggc gggaatcaaa gaaattctga
     8521 ttatttcaac gccacaagat acaccacgtt tcaaggaatt atttggaaac ggaaatgatt
     8581 taggactgca gatcgaatat gcagtacaag aaagtccaga tggattggca caagcgttta
     8641 tcattggaga agaatttatt ggagatgata gtgtctgctt ggtattaggg gacaatattt
     8701 actatggtgg cggtctgtct aaaatgttgc aacgagcagc ttcaaaagat acaggcgcga
     8761 cagtatttgg ctatcatgtc aatgatccag aacgctttgg tgtagtagaa tttgatgaga
     8821 atatgcaagc tttgtcgatt gaagaaaagc ctgctcagcc aaaatcaaat tacgctgtaa
     8881 ctggccttta tttttatgac aatgaggtaa tttctatcgc taaaggtatc aaaccttcag
     8941 aacgtggaga actagagatt acggatgtca ataaagcata tttggataaa ggaaaactat
     9001 ccgtagaact tatgggacgc ggatttgctt ggcttgatac aggaacacat gaatcattgc
     9061 ttgaagcatc tacctttatc gaaacaattg aaaaacgtca gaacttaaaa gtggcttgtt
     9121 tggaagaaat tgcttaccgt atgggctaca tcgataagga acaattgctg gcccttgcac
     9181 agccattgaa aaaaaatcaa tacggtcaat atttattgaa tttggccgct gaataaggag
     9241 tccttacaga tgaaagtaac agatacaaaa ttaacagatg tcaaaatcgt agaaatggac
     9301 gtctttggcg atcatcgcgg tttcttcaca gaaagttatt caaaagcaaa atttgcagaa
     9361 catggattga aatatgactt tgttcaagac aaccattcac tatcagctga agctggtgtc
     9421 cttcgggggc ttcatttcca aaaaggagaa gctgcacaga caaaattgat tcgggtagtc
     9481 actggagcag ttttagatgt agtagtggat atccgcaaag gtagcccgac ttatggtcaa
     9541 tgggacggat ttatcttatc tgaacataat catcgacagt tgcttgtacc taaaggatat
     9601 gcccatggat tcgttacttt gacaccaaat gtgaacttcc tttataagtg tgataattac
     9661 tataatgcag aagcagatgg gggcatcgca tttgatgatc cagatttagc gattgattgg
     9721 ccaattgatc catcaagagc gattatgtcg gaaaaagatc accgtcatcc gacattaaaa
     9781 gaatttgaag cagaaaatcc atttgtttac ggagaaatct aagaattaag gagaaatttt
     9841 cttatgaaaa acatcattgt taccggaggt gccggattca tcggctctaa tttcgttcat
     9901 tacgtggtaa acaatcatcc agaagtgcat gtcactgttt tggataaact gacttatgca
     9961 ggaaacaaag agaacttggc tggacttcct agcgatcgcg tagaattggt cgtaggagat
    10021 gttgcagatg cagaattagt ggaccgtcta gtaaaagaag cggacgcagt tgttcattac
    10081 gcggcagaat cccataacga taattcatta aaagatcctt tcccatttgt acaaacgaat
    10141 atcattggta cgtatacact tttagaagct tgccgcaagt atgatgtacg ctatcatcac
    10201 gtatctactg acgaggttta cggcgatctt ccattacgtg aagacctgcc aggacatggg
    10261 gaaggcgaag gagaaaaatt cactgcggaa acaccatata atccttcaag tccatattct
    10321 tctacaaaag ctggttcaga tctgttagta aaagcatggg tgcgttcttt tggcttacgt
    10381 gcaaccattt caaactgttc aaacaactat ggtccttatc agcatattga aaaatttatt
    10441 cctcgccaag taacgaatat cttaagcggt attcgtccaa aattatatgg cgaaggaaag
    10501 aatgttcgtg actggatcca tacgaatgat cattcttcag cagtgtggct gattttgacg
    10561 aaaggcagaa ttggcgaaac ctatctgatc ggtgcagacg gtgaagaaga taataagacc
    10621 gtgatggaat tgatcttaga aatgatgggt caaccaaaag atgcgtacga ccatgtaaac
    10681 gaccgtgcag gacacgactt gcgttatgca atcgattcga caaaattacg ggaagagtta
    10741 ggatggaagc ctgagtttac gaacttccgt gatgggttgg ctgacacgat caaatggtac
    10801 gaagaacatg aagactggtg gaaaaaagaa aaagaggccg ttgaagcagc atatgccaaa
    10861 aatggacaat aatacagaga aaatgtcact gtattaatgg aaaaacacat gtgaggcagg
    10921 cgctcgcctg tctctttttt aaaataaaaa tcaaggagcg gataatcata tgtttttatt
    10981 aactggagga aatgggcaac taggtacaga attgcgccat ttattagatg aaaaaaatct
    11041 gcaatatgtt tcaacagatg caaaagactt ggatatcaca gatgccgaga aaacaatggc
    11101 ttacatcaca gaattaaaac ctgatgttat tttccattgt gcagcttaca cagcagtaga
    11161 taaagcagaa gaagaagcaa aagaattaga tgagaagatc aatgttgatg gtacaagaaa
    11221 tgtagcactt gcagcaaaag ctgtgaatgc tcaattcgtc tatatcagta cagactatgt
    11281 tttcgatgga aaaaacaaaa atgtagaata cgaagtagac gaccaaacga atccactaaa
    11341 tgaatatggt cgtacgaaat tattaggcga aaaagcagta gaagagattt tagaagacta
    11401 ttatatcata cgaacttctt gggttttcgg gatctatgga cacaatttcg tcttcacgat
    11461 gcaacgccta gcggaaaccc gcgacaaact gactgtagta aatgaccagt ttgggcgacc
    11521 aacttggaca cgtactttgg cagaatttat ggtatatgtc atcgaagaaa aagcaccatt
    11581 tggtatttat catttgtcga acgaaaatag ctgttcttgg tatgaattcg caaaagaaat
    11641 attgaaagat acagatgtag aagttgcacc tgttacgtca gaagaatttc cgcaaaaagc
    11701 aacacgtccg cagtattcag tcatgagcct gaaaaagaca gaagagttag gatttgtcat
    11761 accaacttgg caagaagcac ttgcgcaaat gctggaagct gccaaaaaaa tgaataagta
    11821 atttcctttt atcaaataga atttggagca tgatatggaa aaacaaacaa gaagtgcacg
    11881 acgaaaagaa aagccaaaag cgaaccaggc agattcgaat ttggtgcttg acctgtttct
    11941 aaaactccgc tatcttattg gcgttttagt catcgtggtc atcgttactt ttaatttaaa
    12001 cggaagttca cttggtgttt gggataaata tgtgtcgcaa agagacgatg ggaaaaaaac
    12061 tgatgtgatt tttggacaga atcgggaagt gcggtcagac gaatggctgg tgcagacacc
    12121 tttttacctc tcacaagctg aagaggactt tccgttggtg aacgaggatt attcattaaa
    12181 cggacaaaac atgatcattg cgtataattc tcctgtaaag gatattacgg ttatcggaaa
    12241 accattcaac tggggattct ttttcctcgg aagagatcga ggactttcct tttattgggc
    12301 gatgaaatta gtcgtcatgg tcttgcttgg attcgaagta ctgatgatat taacgaagag
    12361 aaaaaaagct ctatcgctaa tcggtgcatt tgcgctgaca ttttctccag cagtccagtg
    12421 gtggttcatg caacatgtgg gcgatttgat tttctttact ttgggactga tgactgcttt
    12481 ttatcattat ttctacaatc atgataaaaa atggctacga acgttgatga tgcttttggt
    12541 ggttattttc ggtattgggt ttattttagt gatttaccca gcccatcaag tgatgctggc
    12601 gtacttgctg attttttatt ttgttggcct gcttatttac tatagcaaga aagtttcatg
    12661 ggatctgttg gatgtagtgt tgattggagg ggcagtttta tttattggcg gagtcatggt
    12721 tcatttctgg ctaacgtcaa aagacgcatt gttagcttct ttgaatacct tatatccagg
    12781 aaaacgggta agtactggag gaaagtggac gattggcgaa tttttttctt tccttacaaa
    12841 ttggaaaatt ccttttgaag atatcaacta ttcgaataac tctgaagtgg ccctgttcta
    12901 tcactttttt ccaactgtat tcctagcaag tccatttgtg ttatttggca aaaaagatag
    12961 cgaacaaaag ttactgggac gtattttgat gattttttgt ctgttttcta tcttttggat
    13021 taccgttggg ttgccaaaat ggctagcaga aatcactctg ctgtcttatg ttcctccatt
    13081 aagagccatc cttactttta gttttgcggc ttgtttatta tcgatctggt ttatcgctta
    13141 tatttggaga gaagatgtta ttcctatttg gtataaattc attttgttgg cagtaaatgc
    13201 atggtcttat ttctatgcga ttacgcattc gaaaatggat aattattttt cggattttga
    13261 aaccatcgca gttgctgtgt tgggaacagt gattttagct tttgcattat ttggctggag
    13321 acgcttgttt tacctcgctt ttgccgcctt agttatcgta tctggctttt tcgtcaatcc
    13381 agtcgtagaa ggtacaggag cgatttttga aaaaacactg gcaaaagaaa tccaaaaaat
    13441 cgatcaacaa gatcctggta aagtttggtt gtctgaagat gaattatata acttcacccc
    13501 aacattggga gtgaaatcct tcaatacagt acgcttttat ccagatatag ctgcatggaa
    13561 gaaaatcgat ccgaaagaag aatacgagaa gtattataat cggtatgctc atacaagagc
    13621 ttttatcgct aaggaagata caaagttcat tttagatcgt ccagatatgt tttcggtcac
    13681 gttgaatttt gaagacgcag aaaaattagg gatcgactat gtgatcagta aacgaccatt
    13741 aactgattac aaccaattat atgaagcgca gttcacgcag ctatatggac cggataaaga
    13801 cggttatatg atttttaaag tagaatatcc ggattatcca gatgtaccac aaacacaaac
    13861 tcaggaaaat cagctagtcg tacagtaata ggctagctga gaataatcct gaaatgttag
    13921 tagaaaggag agtggagata attcaagcaa tcgtacaaaa atttgtcaac aaaatgagtg
    13981 tcggtttctt gcttttgtta ctgacgctag tcttttttgt ttggacagca gggttaggtt
    14041 ttccagcaac tttgtttata tataacaata gttcattact tatcgctttt agtgtggcta
    14101 ttttgctcat tttaaatgtt tataaagcaa aaggcgtcga ttttctttat ctaggtgttg
    14161 cgcttgccct tttcattttc ttttcttact ttcgggaatt aagaaatgag tctttatttg
    14221 gagacttact gtttcctttg attattttat tttgtttagt aattaaatgg atcgagtgga
    14281 caaaatggga tcgcggtatt tatctgattg tcttttcggt cttcctcgga atcacgttta
    14341 tcgtgtattt acagagatcc aagtaccaga aggacaaagc atctgggctc caggcaattc
    14401 gctttctgat atttggatca atacgaatac aatcggaagt tctttgatga ctcttgcttt
    14461 attgatcagt ggatttgcca gttcttttga acgatggtat gtacgaatca tcggtgcagt
    14521 agcagttgtt gcagcttttc tcgggatttg ggtctgccaa tctagaggtg cattagtcgc
    14581 gttgattgtt tttgcgatat tggatctttt acctaaatcg ttgatgcgtg tcattcgtgc
    14641 gccatttatt gcttacacgg ttacgattct tttagctttg ccgatttctt atctggcggc
    14701 tgtctctgaa aaagtcaatt tgtttaccgg tcgagaagat atttggcata aattctatca
    14761 gacgctagga gaaaaatctg aacaaatttt actaggaatg aaaacattta tcttccaacg
    14821 aggaaaccaa tttttaggaa accacaatag ttataattct attttgaata tctatggatt
    14881 gataggattt gggattgctg ctttgctgct tatccttttt attggtcgct taacgttgaa
    14941 agcagattta tccaacgggc agatgacttt tatctgggcc ttttttgcgg tgatgatgca
    15001 gtcatttatg gaggatacat tgacttcata accatgggtt ccgattattt atatcctgtt
    15061 ggctatggcc gttcatcgat atgatgaacc agaagttgcg gaggaattct atgttatgga
    15121 agaggcatat gacgatatga cttatgatga tacatcttat gaggaacaac cagatagcgc
    15181 tcattcttcc aggatccaac gctatcattg ataggcacaa aatacgagag aggctgtgac
    15241 aaccgtcgca gccttttttg gtttattgca attgtctagc atcttctgta aaatagaaac
    15301 gttagagaaa atcttgtatc atagaaaatt aagaaagaaa taagaacgca gctcggtacc
    15361 aaaaatatgg taaaatggca cttgactgta attcactgaa aatcgcttgg aggaacacaa
    15421 atgtttaaag atttgtattt atttatgaag gacatttatc agaacagaaa attattgcta
    15481 cagttttcga tcaatgactt caaatcaaga tatgcaggat cgtttttagg aatcttatgg
    15541 gcgtttatca atccgctatt tactgtattg atttattggc tggtatttgg tgttggactg
    15601 aaagcacaaa tgatcgatgc aaaataccca tttatcgtat atttagttac cgggatgatt
    15661 ccctggttct tcttctcaga tgcatttgca tcaactacgg ttgtttttcg ggaatatact
    15721 tatttagtaa agaaagtcgt attcaatatt cgtatcttgc ccacgacgaa aatcctatcc
    15781 aatctgtaca cccatttatt cttcattctg attggcatag ctgtcgcgct tataaatggt
    15841 atatatcctt cagcaatgtc tttacagctg atttattatt tattttgcat gtgtgctttc
    15901 ttgacaggat tgacttggct gacggcatcg atccaaccat ttttacctga tatcatgcaa
    15961 ttaattacga tcgtgctgca gttgatcatg tggacattac cgatattatg gagccctaat
    16021 cagtttgatt caggtcttgt aagcatattg aaattaaatc cgctgtacta tgttgttcaa
    16081 ggttatcgtg agtcattttt aagtgaagct tggttctggg agcatggaac atatactttg
    16141 tatttctggg ttttcacgtt agtaatgttc gtaatcggct ctgcagtgtt ccgtagattg
    16201 aaaccacatt tttcagatgt gctgtaagga gaatagctat gacagaatat gcaattagac
    16261 taaaagatat cacaaaatct tataatatgt acgcaaaacc ttcggatcga tttcgtgaag
    16321 ccctcaatcc ttttaagaaa tcctatcatg atgtatttta tgcgttgaaa aacgtgaatg
    16381 tagaaataaa aaaaggtgag atgatcggtt tcgtgggaga aaacggatcg ggaaaatcta
    16441 caatgttgaa aatcattacg ggagtactga caccaacatc cggcacgatg gaaatcgaag
    16501 gaaaaatctc agctttgcta gaactaggat caggattcaa tcctgagtat tctggctatg
    16561 aaaatatcta tttaaatgga atggttctag gattttcaag agaagaagtc gatgaaatgg
    16621 tcgatgatat cattgaattt gctgacatcg gagaccatat ttatcaacct gtaaaaactt
    16681 attcaagcgg gatgttcgtt cgtctagctt ttgctgtagc aatcaatgtg aatcccgata
    16741 ttttgattgt ggatgaagca ttggcagtag gcgatcttga atttcaacta aaatgtatgg
    16801 aaaaatttac agaaatcaag aactcgggaa agacgatttt attcgtttct catgatatca
    16861 gttcgattcg tcgtttttgt gatcgttcct attggttgaa aaacggagaa gtcgtcgaat
    16921 atggcgatac gatggaagta acgacgaatt atgaaaactt tttaaagaaa aaatcagtta
    16981 aaacagtgga tcggaataaa aaccaagtag aacggttcgc cgctccagat atcgtcgacg
    17041 tgacgaaagc ggaattgttg gataaagaca aaaatccggt ggatatgctg gaacaaggag
    17101 aaaaactata cgttaaagta acttatgaag taaaagatga tacaatcaaa aatccggttt
    17161 taggaattgc gctacgaaca gtcgacaatt tttatgtatg cggacttaat actctactag
    17221 atggtatcaa gattccttgg aaaaaaggag agaatatctt ttatctggag tatgaaaagt
    17281 taggtttgtt agctggtgaa tattattttg acgttgcggt ctttgaagaa aatgcaacgg
    17341 ttcctttggt atataagaca aagtacatga acttgtttgt cagcggttct tatatcggag
    17401 aaggcatcgt ggtcttagac cataaatggg aagaagggac tcatagcaat gaaatatgat
    17461 tttgaaatgg acctagatga acaaagcagt gtgggaaaaa ttgccgcaca gatcaaacca
    17521 ggaagtaaag ttttagagtt tggtcccgga aacggccgat taacgaaaca tttaatcgga
    17581 gcaaaacaat gtgaagtgag cattgttgag ttagataagg aattgttcga ttttgtcagc
    17641 gaatttgctc aagatggatt ttatggtgat atcgaaagtt ttgagtgggc aaactattat
    17701 gctggacaga catttgatta cgtcttgttt gcggatgttt tagaacattt ggtagatcct
    17761 ggaaaaacat tgaagaaagt cagagaattt ttgaatgaag aaggagagat cctgattaca
    17821 ttccctaact tggcgcataa ttctgtcatg atcgatttgt tcaataacca attgccgtgg
    17881 gcttcttatg gtctcctaga tgaaacccat aattcttttt atactcatga tggcttccaa
    17941 aaagtttttg aaaaagcggg attattcatt aatattgaag attatttgta cttagctgta
    18001 ggtgatacag aattaaaatc aacttatgaa gaattgccgg aagctgtacg ctatgatttc
    18061 aaaatgcgac catttggtga agtctaccaa tactttttct cattgatgaa acatccagta
    18121 gcacaaagtt ccattgcaga gccacaaaat tctaattatg taaaagtgtt agaagtaacc
    18181 cagcaaacga aacaagatga aacaatccaa caaataccat tcaataattt cacaggggaa
    18241 aatgagacac taagtttccc cgtatcagaa acaacagaaa gaatggtgtt tcgcttcgcg
    18301 caacaaccta gctttatcga attcagcgca gaagctgccg gagaaaaact aacatttatc
    18361 gattcgaatg ctgtagtcaa aacagtaaat gattgttatt tgtttgatgg gaaagaatta
    18421 ccagagttcg ttctaacgga tatttctggg aaagaagtga ctatccattg tcactatcgc
    18481 tttatcgggg aattgacacc aacaatgaaa gaattgttgg aaacgattcg tcccatggct
    18541 gaagtcacaa agcagctttc tgagaaaaat gacgaattag aaagagaaaa tcatcatctt
    18601 cttgaggaaa atacaagact agaccatacg ttaaaaacaa ccacaaatcg ctattgcaca
    18661 ttgttggaaa gtgatgaatg gacaataaaa catagactag gacgacgtaa gaaagaaact
    18721 tcgaaaaaaa tccaagaaaa agaactttct atatgtattg acgagaaaat ctgggatgca
    18781 gaaacaaaaa tattaaaaat catcggatgg ggaatcgcta attcggatcg ccagcccttg
    18841 tcctataagt tatcagctga ccaatcgcca tttttcgaag caattcctgt ttcacgagaa
    18901 gaagtcaatc aagcagaaca gctcgcaaaa ggaacagaag cgggatttga gttacgaatc
    18961 ctttgcgagc aagaacgttc attcttagtg gaagcagtag ctcaaaatgg ccaatcatgg
    19021 atcattgaaa tgtaaataat gattaactta taaagataag gagtaaacga atcgtgcaaa
    19081 aaaaagaaat tgccgtattt atcgatcaaa tcactcgtga acgggccact ggcgatttgc
    19141 ttattgtggg ctgggcaatt gatgaagtga ccaaagaaat ccctacgata aaggtagaaa
    19201 aagaaaatgt gattgctgaa gcaacacatg tcgtaagatt ggatatcaat catttatata
    19261 atcttgatgt taagacccaa agcggtttta aggtacgttt atcagggaaa atgagaggaa
    19321 aagccatctt agacttccaa acagcgagac atcaaaatgg catagctgtg aaattaaacg
    19381 gtaaataccc ttatgatgac ggcattgaat cttcatggga aagaaaaaaa agattactga
    19441 aaaaagggat aaattatgca aggactcatg gcgtaaaaaa agcgatccgt cgggtcaaat
    19501 tggaattgaa gccaggatcg atcgactatg cagagtggat cagtcgtcat gagaaaccag
    19561 atttgaaaga gcaaaggaaa gaagcacaag gatttgcgta ccgtccattg atttccatac
    19621 ttatgcctgt ctataacgtt gaaatcaaat ggctcgaaaa atgcattgat tcggtactgg
    19681 atcaaacgta tgatcattgg gaactatgta tcagtgatga tgcttctact gatccagcta
    19741 tccgaaagtg tctggaatcc tatcaagcaa aagatgatag aatcaaagtc gttttccgaa
    19801 aagaaaatgg acacatcagt ctggcaacta attctgcatt ggaaatagca gaaggagaat
    19861 ttatagcact cttagataat gatgatgaat taccgccatt tgcattatat gaagtggcaa
    19921 aagtgctaaa cgtacatcca gaactggatg tgatctacag tgacgaagat aaaatcgatg
    19981 cagatggcaa tcgctttgat ccgcatttca aagcagactg gtcgcctgat acattgatgg
    20041 gaaataatta tatctctcac ttaggcgtat atcgaacaag cattgttaaa gaacttggcg
    20101 gtttccgtaa aggctatgaa ggttctcaag attatgattt ggtccttcgt gtgacagaac
    20161 aaatccctgc agatcatatt taccacattg accgagtctt gtatcattgg cggacgatcc
    20221 caggatcaac tgcaagtaat ggcgaagcca aaagttatat ctatgattcc ggagtgaaag
    20281 cattgacaga tgccctgtct agaagaaaca tcaaaggaag cgtacgtcct ggcagaattt
    20341 ctggatttta tgagattgct tatgacgtct tgcaagagga tttggtcagt gtgatcattc
    20401 caacgaagaa tggctatgaa gatctaaaaa cttgtgtgga ttcgatcatc gaaaaaacgt
    20461 cttattcaaa ttatgaaatc attattgcgg ataacggaag tacagatcca aaaatgcaag
    20521 aattatttgc agaatacaag catcagctga aagaccgctt tatcgtagaa ttgattgaca
    20581 ttccattcaa ttattctcga attaacaatt tagcagcaga aaaagcaaac ggcaaatact
    20641 ttttattctt gaataacgat acagaagtga ttgagccaga ttggatgacg gtgatggttt
    20701 cttatgcaca gtttgatcga atcggctgtg taggagcaaa actgttttat ccagatgata
    20761 caacgcagca tgcaggagta ttattaggaa tcggtggtgt tgcagggcat gcattgaata
    20821 actatgatcg aacacattgt ggttatttcg gccgattggt cattgacgtc aattacttag
    20881 cagtcactgc agcttgtatg atggtcaagg cagctgactt caatgctgtt aacgggtttg
    20941 atgaaacatt agaagtagca ttcaacgatg ttgacttgtg cttgaaagtt tatgaactgg
    21001 gtcgttacaa tgtctatgca catcaagcag aattgtacca tttcgaatct aaatcaagag
    21061 gttatgaaga tactccagaa aaacaaagac gttttgctgg tgaaatcaaa aaaatgcaag
    21121 ataaatggcc agcatatatt gcgcatgatc cattttacaa tgataattta acaaaagaag
    21181 gaatcggcga cttttcgttg agaccagatt aaactataat aaaaagctgt tatgttgtga
    21241 ttcgctcgca cataacggct ttttatagtt ttttgtcaaa aaaaggcaga aggtgccgac
    21301 tcaaaaaaat aagtcgaggt tgggacagaa gtgtttaact ccgagaaata agaagaaatt
    21361 cacgaaaatt gcttttcaaa tttttgtgaa tttcggctta tttaagaaga agttgcttct
    21421 gctcccaccg tttattcgtt tttaaagaat gagacaaaag tgtttcttac ttttgtccca
    21481 cgctcttatt catgctcaga gcgccaatag atacaaaatc atagccaaag tttcacgaac
    21541 cctagctgtc aaagaatcga tattttattt taatataggc tattttaaaa taaatggttt
    21601 aaggtattcc tctacaaaag ccactctatc aattatcatg ggtttaaaat aagaagtgat
    21661 ggagataacc agattgttct tagcgtcaat ataaagaaca tttccactat taccaattgc
    21721 tgaatatatt tcgttctcag aatctaatac ccaccataaa tagccatatc tcatattttg
    21781 taagtcttct aaagcactgg ttctaggttt gaacatctcg tttatccaca tgggtggtac
    21841 gatttgtttt cctttataca tccctttatt taggcataat acaccaattt ttgccagatc
    21901 acttgccgat aaacacaaac catatcctgc cgtcccgata tttagtggat cacaaaacca
    21961 gacattggtt ttaggagact tatccattgt aaactgctta tgttcttcag ctgtttcagc
    22021 ataataattg acatggtttg gtatccctat aggatcaaat agatacttat tggcaaaatc
    22081 aacagttgtt agcttacttg tctgatacaa caagccagtt aatatgtgta aacagacagt
    22141 ttgatagttg aattcgccgg ttataccttt tcttcctccc aataaatcta gtgatgtttt
    22201 tgtccaatct tcacttgaac agacttttgt ccatggatcg cctttacatt tgtagggtgc
    22261 tttcattgtt agcaagtgct tgattgtaat agcgtaaata gttttctccc cgcgtttcac
    22321 tttatactct ggaaaataat ctaatacttt atcatcgata cttttgatta atccttgctc
    22381 taaagcaatg ccaatcagca aagatacaat acttttcgtt gctgacatga tatgacaagt
    22441 atcgtctttt ttataaccat tccattcatc tgtataaact tctaccccat ccttatatgc
    22501 gacaatttga catatatttg gttgtcgaaa accaataaaa tcatgcaact cttgtttatt
    22561 cataagatat tacctcactt tcttctataa gcataatgtc attaaaaatc gatttcaatt
    22621 ttttcgattc ttcacgtaat acaggtattc ttatggacta gacagcgctt tgggaagatg
    22681 gattctctga aaaatataaa ggttcacttt atgagtggat aaaaaaagca gcaaatactt
    22741 cgacttcttt aatttaccaa cattagtgaa aatcgattca tctggagatt tgtaatttag
    22801 agtccttgtc ttgattagag gtgtataaag ctttttatta gacattttta aattccatta
    22861 caatttgctt ataaactagg tttttaaagg tgactatggt aagataatag agatattatt
    22921 ttgt
//
LOCUS       DAFEIE010000040        22132 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFEIE010000040
VERSION     DAFEIE010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.041"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..523
                     /locus_tag="LP345_001785"
     CDS             <1..523
                     /locus_tag="LP345_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBL1760564.1"
                     /translation="GGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGIVA
                     NCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIFGS
                     LIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILTVL
                     LLPLFFQPFAGLF"
     gene            523..2109
                     /locus_tag="LP345_001786"
     CDS             523..2109
                     /locus_tag="LP345_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760565.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            2128..2349
                     /locus_tag="LP345_001787"
     CDS             2128..2349
                     /locus_tag="LP345_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBL1760566.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            2346..3107
                     /locus_tag="LP345_001788"
     CDS             2346..3107
                     /locus_tag="LP345_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBL1760567.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            3487..3996
                     /locus_tag="LP345_001789"
     CDS             3487..3996
                     /locus_tag="LP345_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL1760568.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(4071..4610)
                     /locus_tag="LP345_001790"
     CDS             complement(4071..4610)
                     /locus_tag="LP345_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBL1760569.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="LP345_001791"
     CDS             complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="LP345_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBL1760570.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            5623..6474
                     /locus_tag="LP345_001792"
     CDS             5623..6474
                     /locus_tag="LP345_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBL1760571.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            6502..7137
                     /locus_tag="LP345_001793"
     CDS             6502..7137
                     /locus_tag="LP345_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBL1760572.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            7157..7930
                     /locus_tag="LP345_001794"
     CDS             7157..7930
                     /locus_tag="LP345_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1760573.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            8338..9135
                     /locus_tag="LP345_001795"
     CDS             8338..9135
                     /locus_tag="LP345_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBL1760574.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            9113..9526
                     /locus_tag="LP345_001796"
     CDS             9113..9526
                     /locus_tag="LP345_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL1760575.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            9510..12155
                     /gene="mutS"
                     /locus_tag="LP345_001797"
     CDS             9510..12155
                     /gene="mutS"
                     /locus_tag="LP345_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL1760576.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            12173..14281
                     /gene="mutL"
                     /locus_tag="LP345_001798"
     CDS             12173..14281
                     /gene="mutL"
                     /locus_tag="LP345_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBL1760577.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            14303..14863
                     /gene="maf"
                     /locus_tag="LP345_001799"
     CDS             14303..14863
                     /gene="maf"
                     /locus_tag="LP345_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBL1760578.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(14948..16936)
                     /gene="treP"
                     /locus_tag="LP345_001800"
     CDS             complement(14948..16936)
                     /gene="treP"
                     /locus_tag="LP345_001800"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBL1760579.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            17159..17872
                     /gene="treR"
                     /locus_tag="LP345_001801"
     CDS             17159..17872
                     /gene="treR"
                     /locus_tag="LP345_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBL1760580.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVLHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            17949..18395
                     /gene="msrB"
                     /locus_tag="LP345_001802"
     CDS             17949..18395
                     /gene="msrB"
                     /locus_tag="LP345_001802"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBL1760581.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            18565..19167
                     /gene="ruvA"
                     /locus_tag="LP345_001803"
     CDS             18565..19167
                     /gene="ruvA"
                     /locus_tag="LP345_001803"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBL1760582.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            19180..20181
                     /gene="ruvB"
                     /locus_tag="LP345_001804"
     CDS             19180..20181
                     /gene="ruvB"
                     /locus_tag="LP345_001804"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBL1760583.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            20210..20788
                     /locus_tag="LP345_001805"
     CDS             20210..20788
                     /locus_tag="LP345_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1760584.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            20840..21322
                     /locus_tag="LP345_001806"
     CDS             20840..21322
                     /locus_tag="LP345_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBL1760585.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            21439..21813
                     /locus_tag="LP345_001807"
     CDS             21439..21813
                     /locus_tag="LP345_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760586.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7238 a         3991 c         4789 g         6114 t
ORIGIN      
        1 cgggggcaat tttttgacta tgctgattac tcctgcgaca gtggcacttg ccatccctct
       61 ttataaaaac ttccgtttac tgaaagagaa tttttatcct gtaatggctg cgattttagc
      121 aggaatagtc gcaaattgct tggttagtgt agggttcggt tacttcttct ctcttcataa
      181 agagatggtg atctcattac tacctaaatc tgtaacgacg gctatttctg tcgatttatc
      241 tcatacgatg ggcggggtga atgccgtgac acttgctatt gttgtctcta caggtatttt
      301 tggttcgctg atcgccactc atattttccg cctattcaag atcgaaagtc cagttgctcg
      361 cggtgtggcg ttaggaagta cttctcatgc tattggtaca gcaaaagcaa tcgagattgg
      421 tgaaatagaa ggaatcattt ccggacttgc gatatgcgtc aacggaatat tgaccgtttt
      481 attgctaccg ttattctttc agccttttgc tggcttgttt tgatgcgaaa accactattt
      541 tatgctacaa taaccaaaac gttcgagcat aaaaaaggag ggaaagacgt gtatttgtct
      601 tccgagtatc ttaaacaatt tgataaagat ctatattata agattctcct cctagaaagt
      661 tttgaggatc aagcttggca taccgctgca caattagcgc aagttgttca gctggatgcc
      721 cgcagcgtgt cgaaatacct gaacgagctg tctaaaaact atcagcagtt tagcggtaag
      781 acacaccctt tgtttacaaa aaatcaccgt tctggttata acttttatga tacgctcgat
      841 tcaattgaac atgagcgttt tttgatctat ctcgtgcaaa gtacgctgaa attccagttg
      901 ctgcacgaca ttttttttga agaattccat acaatgtacc aatttgcgca aaagcattac
      961 attagtgaat ctactgctca tcgaaaaatc aatgaatgga aacagcaact gcaaacttac
     1021 ggaattcggc tgcaacgagg tacatatatc gctcaaggcg aagaagaaat cattcgactt
     1081 tacttgcata tgacattctg gcagttgttt cgagggaaaa tctggccatt tgaaacgatt
     1141 tctcaaatgg acgtaaagaa tatggcagaa catatcatgg ctttttttaa tgttcgtctg
     1201 aacgagatca aaaaaagacg attggaatat atgctaggtg cctttttttt aagaaaatca
     1261 cagaagcatt atgttgtatt gaatgagaaa aaaagacggc tgatttctga caatctgttg
     1321 ttccagcgat tttgccaggt catggagccg gtatttccta attattttca agtagaagac
     1381 gagttaggcg cattatttct tgtactgatg actcgtgaag aatattatag tgatcctaag
     1441 atacggaaga aaatttttga ttttcatcaa caagcaaaaa caccgccctt tacagccctt
     1501 tcagaagcaa aagccgctct ttctctttat caggaagagc aggggctgcc agcagaaaat
     1561 ctaaccttcg aggcagaaaa ctatttattc agcagtcatt ttttcgccta tctttttcct
     1621 aatgcgaaag aaacgattga tggcaatagt agtgatttta ttaatcattt agttattgaa
     1681 aacaaggaat tgaaacaatg gctcgtacat ttttttgaaa gtagacacaa acatcccaat
     1741 catctggcat ttaaaaatca tgcgtttttg atggggcggt atctgactgt gtttaaaaca
     1801 ttaggagcct ttactccaca gcttccaaag atcacgatcc ttttaatgac agatttccca
     1861 ttatttgaag agcaactgtt agaggaggga ttacggacat ttttccgtaa tgagtatcag
     1921 ctgatttttc tgccaacaga ttatcggggg agagaagttg atcttctgat ttcgacaagt
     1981 aaagtccacc gcaaaccatg ggcggatctt gactatttta ttgtgactga agaactaaaa
     2041 ttaattgatt acatccaact atctcaaaaa tttgaaatga ttcaaaaaca aaaactatta
     2101 aaacaataac aaagaaggag aaaaaagatg acatttgaag aaattttacc agaattgaaa
     2161 aaaggtgcaa agattattcg taaaggatgg agtggatttg aactttatgt tgttctcgta
     2221 tccgatgatg aatttgatgg ctgtccggtg acgccgtact tattgatcaa aacaagtgac
     2281 gaaggttttt ccagcttcgc tcctacagtt tgtgatattt tagcagatga ttgggcgatc
     2341 gtagaatgaa aaaccagtat ccagatctag ctaaacaggt tgtatttatc acaggagctg
     2401 cttctggaat tggtgctgcg caagcccgag cgtttcttga acaagatgct tttgtatttg
     2461 gattagatca aaagttcggt aaaatggaag aaatttcttt gcgatttcct gaaacttttg
     2521 cctacgcact aggtgatgtt cgacaaatga aagaactcca acaagcggta tcgaaatgcc
     2581 aaaatcattt tggtgaagtt acgattttac tgaatacagc ggggatattg gatgcctaca
     2641 aacccttgat ggaaactgac gaatcgctgt gggatctgat ttatgagacg aatgtgaaaa
     2701 gcatgtatca gctgacaaaa atcatccttc ctgatatgat ccgccaaaaa agcggaacga
     2761 tcatcaatat ggcttcgatt gctggcttga ttgctggtgg aggtgggatc gcttatacaa
     2821 gcgcgaaaca tgcgattgtc ggatttacca aacaactcgc tctggattac gcaggacagg
     2881 gtatccgagt aaaaggaatt gctccaggag ccatccaaac accaatgaat gcggctgatt
     2941 ttgaagggaa aggtgagatg gcagagtggg tggcaaatga aacaccagtc aagcgatggg
     3001 cacagccgga agaagtagct gagctgacgt tatttcttgc ctctcctcaa gcaagctaca
     3061 tacaaggaac gatcatccca atcgacggcg gatggttgtt aaaataacct tgtgtttttt
     3121 tcaagcttct gtatgataaa actaaagaga gaaacaacgg ttgatgataa aaaaagtcga
     3181 tgactgttcc cgacattcga tgccgaacag ccagttcaaa aaattctttt taataatcgt
     3241 taatattcga aactaagcgg cttttcacga cctcttgata taaacgatat tcaaaagctt
     3301 gcaactgcgg taacaagtcc agccaaatga aaaatataag gagctatttt tatttgacca
     3361 ttcttattac ttgttgcagg gcagcttttt cactaccttc tgcgacactt cagttggaat
     3421 tttcttccca tcctttggtc gcggtcatta ccaagataaa attatcttgc aaaggagaaa
     3481 tagaacatgg aaaaaaataa tacccgttca gccaaacgct ggacaacgac agatgtgact
     3541 cggatggcgc tagtcactgg tttatatgtg gcagtgacgc tggttttgtc tgtctttagc
     3601 tttggagtga ttcagattcg tctctcggag atgttcaact atctgtcctt gtataacaaa
     3661 agatacatcg tcgcggtaac agcgggagta gctttggcta atattgcttc tcctcttgga
     3721 ctgatagatg ttgcagtagg aagcgtcagc acgctgcttg tattgcttat caactataaa
     3781 atcactagtc gcatcaaaaa catgaaaatc aaaatggccg tgacagcatg cgtatttgct
     3841 ttttccatgt ttacagtagc tggtcagcta acgattttat atcaactacc ttttttcttg
     3901 aattggtggg tgattgcttt aggagaattg gcatcaatga ttgtcggtgg gataattatt
     3961 tattggatcg gtaaaaaagt ggatttgtca aaataaagat ctgtttaatt taaaataggg
     4021 cagcatggaa gagactgaat gttgagtctt cttccatgct gcttttttga ttaatttgta
     4081 tgaagaaatc gatttagccg ttttttcatc aagataccga tataagctgc tccagttgcc
     4141 ttgattgctt ccggcagtaa aaacggcagt agtccactgg caaatgcagt tgtaaaagta
     4201 agatcaccac ttattttcag ccagatcgtt ccgcagatca atgcagcaag agagcccatt
     4261 agattggcaa agattgcata taagtaatga gcatccgttc tttcgatcat ccaaccagtt
     4321 atccacgttt gtaagagaaa tccaatcaaa tatccgccag ttggcccaaa taaaacagct
     4381 atacctccag tcatccctga aaatacagga agaccaatca agccaagtaa aagataaact
     4441 ccaacagata tcaatcctag ttttcttccg agaaaagttg ctgttaatcc aatagcaaat
     4501 gtttgccctg tcaaaggaac caaaccaaaa ggaatggtca tctgagaaag gacagaaata
     4561 atcgcggcaa attccgcagc aagtatcaat tctttcaatg ttcggttcat aacgccctct
     4621 tttcgttaac ttaatatttt taattggtta acgaaattgt aaaacaaagt gattactttg
     4681 taaatagaaa atataaaaaa agaccagcta tccaatagat agcggtcttt ttcaagaaag
     4741 cttttgaaat tataagcttt ggttgtagta ttcaacgaca agagcttcgt cgatttctgg
     4801 atatagttcg tcacgttctg gtaaacgagt caatgaacct tccaattttt cagcgtcaaa
     4861 gcttacgaat gctgggcgtc caacagttgc ttctacagct tcttttactg ttacgatgtt
     4921 ttgtgatttt tcacgaactg agatcacttg acccacttct acgtggtatg aagggatatc
     4981 aacgcgtttg ccatcaacta aaatgtgacc atggttaact aattgacgtg cttgacgacg
     5041 agtcgttgca agtcctaaac ggtaaacaac attgtctaaa cgttgttcta gtaagatcat
     5101 gaagttaaca ccatgtttac cttctttgat tttgctagct tttacgaaca agttacggaa
     5161 ttgacgttcg ttcattccgt acatgtgacg aagtttttgt ttttcagtta attgcatgcc
     5221 gtattctgat tgtttgccac ggctattagg tccatgttga cctggtgcgt aagggcgacg
     5281 tgctaattct tttcctgtgc ctgacaatga gatgcctaag cgacgagaaa ttttccatga
     5341 tggtcctgta taacgagaca ttaaaatttc ctccaatgaa tataagtttt tggagtaaaa
     5401 taatccgttg aaaaattcat aatcatatag tttgttcttc aatcttcacc tttgcagccg
     5461 cggttacaca atcgaacccg agacggggca acaaactagg gatgagttat tatttttctg
     5521 ctgcattatt ttacacaaat tacagtatat gatagatcat ccacgaatgt caagataatt
     5581 agtacataaa aacgctttac aaacctaggc tgtctttata aaatgagagg gtatgtgcaa
     5641 atggaaaaaa gcgaaggaag tttaaggaga aaatcaatga atccggtatc accattattt
     5701 gagaaaatcg atgcttcaat tgaaaagaag gcgaatcttt ttgaaaacag cttttcacgt
     5761 tacgctgttc gagcggttct cgcctgtttg tttttgactt taggaacggc tgtggcattt
     5821 gcgatcgcga tgaaggggga agatatcgcg catggtctag gaaagatttt atacgcattt
     5881 atgttcagct ggggtctggt catgattcta tacatgaacg ccgaattagg aacatcgaat
     5941 atgctttata tgaccgtggg tgtttttcgg cagagacttg ctttaagtaa ggcagccaag
     6001 attctatttg cctgtatttt tttcaatatg attggcggta tattatgtgg atttctaatt
     6061 tctatgacta cgccatttca agatttaacg ttggacaact ttatgttaga atcaatagca
     6121 gtaaaactag caaaaccttc agcaacgatt ttggtggaag ggatgtttgc gaatatcgtt
     6181 gtcaataccg ctgtactgat cagcatgcgg atgaaagagg atgtcggaaa agtgatcaca
     6241 gtcgtattca tcattttcat ttttgctttt ttaggatatg aacacgtgat agcgaatttt
     6301 cctgccttta cgcttactta ctttgcttct cacggacaga tggatggaat gacagtcagc
     6361 aatgtgttac ataatttgtt ttttgctttg gcaggaaatt atattggtgg cggtttagta
     6421 atgggactgg gatatgcttg gctgaatcag tcaaaatcat cctatgtgga ctaaaaagtc
     6481 gttcattaaa ggggaagtgc catggaagtt ttagtttttc caaaaaatga ggaaaaagcg
     6541 ttacaaatgg aaaagtacat gaaaaatctt ttttcctttg ctggagtacc taagccggaa
     6601 cgcgctcttt tacaacaacc gttactggat gagagcaaaa atttatctat ttctgaagtt
     6661 ttagcttttg ttcattatta ttatgaacaa atcgaaagag agtatcagta tgtagcgatc
     6721 gatttagtcc agaaaaacat caaacggctt acatttgaag acttagtcgt attgttgcca
     6781 ctagttcaga aaaaagaatg gtgggacagc atcgactctt ggagaaaagt atacagcaca
     6841 tggtgtaaag cctacccaga gcagcgtgaa gaagtctttc aattgtttga aaaaaaggaa
     6901 gatttttggc tacgtcgaat agcaatcacg ttgcaattag gttataaaca gcaaacagac
     6961 acaggactat tgatccgagc aatagacgaa gatcgtcaaa caaaggaatt ctttatccaa
     7021 aaagcaattg gttgggcatt acgcgattat agtaagaccg atgccgattg ggtaaaaaga
     7081 cagctgacaa cagatttgag taagttagct gttcgagagg caagtaagta tttataagaa
     7141 agcgagacga caagagatga gacgcaaatt atttgctttt gatattgatg gaacgttgtt
     7201 agattcaaac aaacaagctt tagatagcac aagagaagca ttggaaaaat tacgcaaagc
     7261 cggtcatctg gtcacgattg ctacagggcg gagccgattt catgcgcaag agatcattcg
     7321 cgatcttgat tttacgaact acattttatg taatggagcg gccggttttt tagaccatga
     7381 acaagtatat aagaatttac tagatcgcga ccagttggat gcgttcgttc aagaagcgca
     7441 tcatgagcag atcgatacag cttttgtcag cttagacaat atcaagcgtt cttcttccaa
     7501 tgatgtaacg gtgatggaag aagcgatgca ttctttcggt gctgtcttgc ctgaattaga
     7561 tcagtttttt gcagaggaac aagaaatata ccaagcgtta gcatttttcg atcaaacata
     7621 tgatgggaag ttctcttcat atgataaaat tcgatttgtc cgctggcatg agaacagtgt
     7681 agatgtcgta cctaaaaatg gttctaaagc agcgacaatt ctgcacttag cagaacaagt
     7741 aggcatccct catgaagaca tcatcagctt tggcgatgga caaaacgacc gtgaaatgtt
     7801 gcgcatgtca ggaattggga tagctatggg gaatgctgtg ccagaagtac aagcagaagc
     7861 taagatggtc actgatacaa acgatcagga tggaatttgg aaggcattga aagagttaag
     7921 cgtgatttaa aagaggttgt gaaaaagctg ttctgcatca agtaataagc ccagccaaac
     7981 aaaaatagct cctcctattt ttcgtttttc tgggcttatt accgcagatg caagctttcg
     8041 aacaccgttt aaggaagagg tcgtgacaga agtggtcagt ttcaagaaat aagaagggat
     8101 ttacgaaaat tgcttctcaa atttttgtaa aattacggct tatttctgaa gaagtagatg
     8161 aaacaacgtt tattcgggaa atgggactgt gacaagatgt ttgtcatagt cccatttttt
     8221 tattttattt ttcaaaacta agaaatacca ggaaagagtt ccttttgttt gaccttttct
     8281 ttcttattga aaacaactat aatatagagt gatgttaaaa gagaagagga atttagtgtg
     8341 cgggtattgt ttattggtga tgtagtaggt tcaatgggac gagagatgat tactgaatat
     8401 cttcctagat tgaagaagaa gtaccgtccg caagtaacga ttgtaaatgg tgagaatgcc
     8461 gcttctggac gtggaatcac agaaaaaatc tataaaaaat ttttgcaaga cggcgtagat
     8521 gtcgtgacga tggggaatca tacgtgggac aaccgcggaa tctttgagtt tgtaaatgaa
     8581 gctaaaaaga tggttcgtcc ggcaaatttt ccggaaggga cgcctggaca agggatggtc
     8641 tttgtcaaag tgaaccaagt cgaactggca gtgatcaaca tgcaggctcg ttcttttatg
     8701 gtggacttgg atgatccttt tcgtaaaatg aatgagctgg tagaagaagc cagaaaacgt
     8761 acgccgatca tttttgtaga ttttcatgga gaaacaacaa gtgaaaaaca agcaatgggc
     8821 tggtttttag atgggaaagt ttcagcagtg gtcggtacac atacacacgt tcagacaaat
     8881 gatgcgcgaa ttttgccaag aggaacagcg tatctgacag acgttgggat gacaggtccc
     8941 tatgatggta ttttgggtat gcgcagagaa cctgtaatcg aaaagtttct gactgcatta
     9001 ccaaaacgtt ttgaagttgt ggaacaaggc cgatcgattt taagcggctg tatcttggaa
     9061 ttggatgata cgacaggtca tgcaaaagaa atccagctga ttcagatcaa cgatgatcga
     9121 ccgttcatgg agtagaaaga gaggcagttt tttgcagcag gagccggaaa ttcaaaaaga
     9181 agtaaggaaa ctgacaaaac ttttaagaga gaatgaaacg atcattcgct acaaagaact
     9241 tgaagaaaag atccagcaaa accagtattt agctgagttg agagaaaaaa tcaaacaagc
     9301 gcaaaaagat gctgttcatt ttgcccacta tgacaaacca gcagcagaaa aagaagcaat
     9361 caaacaagcg gatcaattca tgcaagaatt tgatcagcat ccgcttgttg tagcttatag
     9421 aaaacagctg ttggaagcag atgatctgct tcatcattta acaactatga tacaagaaga
     9481 aatcaatgga caaatagagg aggaaaaaca tgcctcaaaa aactaaaaat actcctatga
     9541 tggaacaata tctaagcatc aaggcccaat accaagatgc ttttttgttc tatcgtttag
     9601 gagactttta tgaactattt tacgaagatg cgatcaaagc gtcacagctt ttggaattaa
     9661 cgttgacgag cagaaatcga aatgcagaag aacctattcc tatgtgcggt gtacctcacc
     9721 atgcagcaca aggatatatc gatgccttga ttgaaaaagg ctataaagta gcgatttgcg
     9781 agcaggtaga agatccaaag acgactaaag ggatggtcaa gcgcgaagtg atccagctag
     9841 tcactcctgg tacagtcatg gacagcaaag gattgtcggc aaaagacaac aattttttaa
     9901 cagctgtagt tagtcaagga aatgaatttg gctttgctta tgccgattta agtacgggag
     9961 aattgaagac ggctcggttg catgatgaag aagctgtttt aaatgaagcc tctgcattgc
    10021 agacaaaaga actcgtatta ggcagtgaga tcactgatac ccttcgtgaa cagctaagcg
    10081 ggcgtttagg gctagtcttt tctcaacaaa atgagatgga agaaaacgcg gaatttagct
    10141 ttttgacaag cgaactagtc gatccgctgg aaaaagaagc aaccggcaaa ctattgactt
    10201 atttatcggt gacacaaaag cggagtttag ctcatatcca aaaagcagta gaataccaac
    10261 cagatcattt tttgaaaatg gattattatt caaaattcaa cctagaatta agccaatcta
    10321 ttcggactgg gaaaaagcac ggcactcttc tatggttgtt agatgaaaca aaaacagcaa
    10381 tgggtggccg tttactaaaa caatggctag accgtccgct tatccaggca aaacaaatta
    10441 aagcaagaca agaaatggtc gcttctttgc tagacagcta ttttgaacgt atcgatttgc
    10501 agtcagcatt aacgaaagtc tatgatctgg aacgcctagc aggtcgagta gctttcggta
    10561 atgtcaatgg gcgagacttg atccagctga aaacttcttt agaacaagtg ccaatgatca
    10621 gagggttgat tgaaggaatc gatcaaggtc aatggcaaag tctgctttca gaaatgcagc
    10681 cgatggacca tctcgtccaa ttgatcgacc aagctatcca agatgatccg ccgttacaaa
    10741 taacggaagg aaacatcatc aaagatggat tcaatgagca gctcgatatg taccgttctg
    10801 ctatgagaaa cggaaagaaa tggttggcag aacttgaagc aaaagagcgt caagaaacag
    10861 gaatcaagaa cttaaaaatc ggatttaacc gcgttttcgg ttattatata gaaattacaa
    10921 aagcaaatct tggaaatgca gaactggaga agtatgaacg aaaacaaact ttagcaaatg
    10981 cagagcgttt catcacacca gaactaaaag aattggagac acaaatcctc gaagcagaag
    11041 aaaaatctgt tgatttagaa tatcagttgt ttttagctgt gagagaagaa gtcaaaaagg
    11101 ctatccagcc gctacaagta cttgcaaaag caatcagtgc agtagatgtg ctacaaagtt
    11161 ttgcaacgat cagcgaacgc tatcagtatg ttcggccaga acttgtcagt gacaagcatc
    11221 agcttctgat caaagacgga cgacatcctg tagtagaaaa agtattagga catcaggaat
    11281 atatccctaa cagcgtagaa atggcagaag acgaaatgat cttgctgatt acaggaccga
    11341 atatgtctgg taaaagtacg tatatgcgac agttggcatt aactgttctg atggcgcaaa
    11401 tgggctgttt cgttccggca aaacaagcag ttttacctat ttttgatcgg atttttaccc
    11461 gaattggtgc aagtgacgac ttaattgctg gacaaagtac ttttatggta gagatgatgg
    11521 aagccaatca agccctgcgt tatgctacgc caaacagttt gattttgttt gacgaactag
    11581 ggcgaggaac agcaacctat gacggaatgg cgttggccca agcaatcatc gaatatatcc
    11641 atcgtcatgt acaagcaaaa acactctttt ctactcatta tcatgaactg acggtacttg
    11701 agaaagaact tccgcagctt aaaaatgtcc atgttggagc cgttgaaaaa gacggagaag
    11761 ttgtcttctt gcataaaatg atggatggac ctgcggataa aagctacggc atacatgtgg
    11821 caaagatcgc aggattgcct tccaatctac tagaacgagc agcagatatc ctgcatacgc
    11881 tagaaaatgg cgataacgga caccatactg ttccagctga agtagaagag aaaactaaaa
    11941 cagccaaaca ggagcaaata aaaccacctg cagaaaaagt aaatcaagac catatacaag
    12001 accgtgtaaa agaagaaaac caacagcttt ctttattcag tgaattatcc gaaaatgaaa
    12061 cagaagtcat tgaatcactg aagcaaataa atttactaga aatgacgcca atggatgcac
    12121 taaacacatt atatgaatta caaaaacaac tgtaggaaga aggcggatat cgatggccaa
    12181 aatccaagaa ttatctgaac gtttagctaa tcagatcgct gcgggagaag tagtggagcg
    12241 accagcttcc gttgtgaaag aattagtgga aaatgcaatt gacgccggca gtactcagat
    12301 tgatatctta gttgaagaag cgggactgcg gacgatccaa gtgattgata acggagaagg
    12361 cattttggca gacgacgtag agaatgcctt caagcggcat gcgacaagta agatccataa
    12421 tcgcgacgat ctttttcgca tacgaacgct gggctttcga ggggaagctt tgccaagtat
    12481 tgcctctgtt tctgaaatga ctctggaaac ggcgaatcag gaagaaaaac aaggcaccta
    12541 tctgtcgctg aaaggcggag aagttattga gcatcgacca gcaccactgc gtcaaggaac
    12601 gaagattacc gtcagcaatc tgtttttcaa tacgccagcc cgcttgaaat acgtgaaaac
    12661 actgcacaca gaattagcga acatcgggga catcgtcaat cgactggcat tgagtcatcc
    12721 atcgattgct tttcgtttag tacatgatgg aaacaaaatg ctggcaactg ctggaaatgg
    12781 cgatctgaaa caaacaattg cgggaatcta cggattatct accgcaaaaa aaatgctgaa
    12841 aatcgaagga aaagatctag attttgagtt atttggctat gtttcattgc ctgaggtgac
    12901 tcgtgccagt aggaattact tatcgacgat catcaatgga cgttttatca agaacttttc
    12961 cttgaataaa gcaatcgttg caggttatgg gtcaaaatta atggtcggtc gtttccctat
    13021 tgctgtattg gaaatcaaaa tggacccgct tttagtagat gtaaatgttc atccgacgaa
    13081 gcaggaagtc cggctgtcga aggaaaaaga actaacagag ctaattagta acgccattca
    13141 aaaagcattg tctcaagaaa atctgattcc aagtgcagcg gataatctac ggtttaagaa
    13201 aaaagtacct gatcagccta aaacagaaca aatcgaaatc gatttgtcct acgcttttga
    13261 agaagaaaaa cctaaaaagc caagtagttt gaattttgat cgagagacag gtaccttttt
    13321 cgtagaagaa ctaaagaaca catttgttga cagaattgtt gataagtctg tggaaaatgt
    13381 tgaaaactat tctggttttt ctgaagaaaa caccacttat ccagaaaaaa cagcgaaaac
    13441 ggtggataag tttggtgaaa atgttgataa ctttgtagaa aaaacagtgg aaaaatctga
    13501 aaagaaagaa tttcccattg tggataacat ggagaaaaca aatgaagaac aagcagataa
    13561 atccgtagaa gaggatgaaa agatttacga ggaagaattg acactccatc ctgaatttga
    13621 tttcactcaa ggaaacgaca aaacattaga acaagccatc aagaaattag aaacggaaaa
    13681 accagtacaa cgttttcctc agttggaata ttttggacag atgcacggaa cgtatctttt
    13741 tgcccaaagt agcgatgggt tgtacatcat tgatcagcat gctgcccaag agcgcattaa
    13801 gtatgaatat ttccgggaaa aaattgggga agtatctgat gatctgcaag aattgcttgt
    13861 tccatttgtg ttagactatc caaacagtga tgctttgaaa ttaaaagagc aaaaacactt
    13921 gctagaagat gcagggattt atttagaaga atttggtcaa aacagcttta ttgtacgggc
    13981 ccatcctact tggtatccca atggagaaga agaatcgatt attcgggaga tgatcgatat
    14041 gctgctgaca actggaagtg tgagtgtaaa aaaattccgt gaagcaacag caatcatgat
    14101 gagttgcaaa cgatcgatta aagccaacca ttatttgaat gaagcacaag cacgtgtgct
    14161 gctgaaggat ctggcacgat gcgaaaatcc tttcaattgt ccccatggcc gtccagtatt
    14221 gattcacttt accaattcgg atatggaaag gatgttcaaa cgaatccaag acccgcatta
    14281 agtcaaagag aagagggaaa acatgaagat tgtattagca tcccaatcac caagaagaaa
    14341 agagttattg gctcatatcg tttcagaatt cgagattgaa cctgctgata tcgatgaaac
    14401 gccatttcca gacgaacagc ccgtcgatta tgttcgtaga atggctgaag aaaaagcacg
    14461 aactgtctgg gaacaagatg aaaaagaaga ccatttagtg attgccagtg acacgactgt
    14521 tgttctcaat caagagatca tgggtaaacc agaagatctg gctgaggctg aattcatgct
    14581 gaaaaaacta agcggggaaa cacatactgt atatacagct gttgttttaa aaacaaagga
    14641 acgagaagaa cggatactag cagaagcaca tgtcactttt tatcctttga cagacgaaga
    14701 gatcaaacgc tacttggaga cgggggatta tgcggataag gcaggggcat acggcatcca
    14761 aaatgctgcg agtgtattcg tcaaagaaat ttctggagat tattacagta tcgtaggatt
    14821 tccgattggt gctgtcaatc aggcactgaa aacattcatt taaacaaaaa agcggactat
    14881 ctgattttcg attgaaaatc catgatagcc cgtttttttt attgaaaaga ttacttatct
    14941 actctgacta agattttact tcagctttac cgactgcttc gcccgggcga acaagtcctg
    15001 attggtcaag agaaagtcct gcaacttttt cattattggt caaagcaaca ataatgtcag
    15061 ttttcttgcc agcttgttct atttctggca aatccatttc agcaatcagg gtctctggtg
    15121 tgacaaggta tccttctttc acgaatacat tgaaaggaac accctttagt tcaacagtat
    15181 ctaatcccat gtgaacaagt acttccagcc cctcattaga aagaatacca atggcatgtt
    15241 ttgtttcaaa gacactcgtc actttaccgt ttactggtgc atagactttg ccgtttgacg
    15301 gttcgacagc ataaccgtca cccatcattt tttgtgagaa aactgggtca tttacttcag
    15361 ttatttcctt gatggtccct gcagcgactg cgaataatgt ttcttttgtt gcaactgccg
    15421 taccagttgc tgaaacaggt tcgaaagact gtggcgttgc tgttgcgcca tttgctgttt
    15481 gaagttgtac atcagcagca ttttcaggaa cagcaggatc aatcttattc aaaattccct
    15541 gacgtctaaa gatgatcgtc aagccaaatg gaatgatgac agcaatgatc attgcgatga
    15601 tgaaaggtac ccatgtttct gcttggatag ctagtattcc tggcaaaccg cctactccga
    15661 tcgcgttagc tcgaacaccc atcaagttag caaacatgcc agctaatcca gagccgacca
    15721 ttgcagcgac gaaaggatag acgtatttca aattgattcc gaacatagca ggttcagtta
    15781 cgcctaagta acaagaaatc attgctggaa tcgagatttg ttcttctttt ttattcccac
    15841 gatgtaagaa gatgatggct aagactgcag agccttgggc gatatttgat aaagcaatca
    15901 tcggccataa attcgttgat ccgaaatctg caatcagctg catatcgatg gcattggtca
    15961 tatggtggag accagtaatc actaaaggag catacaggaa tccgaatacg gcactaaaca
    16021 accagctgat agaagacgtc aatccagtat ttacgatatt tgagatccag cttccgactg
    16081 tccagccgat aggacctaaa ataacgtgtg cagctaaaac agttggtaac aatgaaaaca
    16141 atggaacaaa aatcatcgag atcgactgag ggatatattt gcggaagaag atttctagat
    16201 acgctaacat aaaccctgcc agcatggctg gaataacttg cgcttgataa ccaatcatct
    16261 ggacttgagc aaaaccaaaa tcccaaaatg gaatatctgc tgcggctgtg gaagctacac
    16321 tataagcatt taataattgc ggagaaacta acgtaattcc taaaacgatt cctaatattt
    16381 gtgtagtacc catctttttt gcaatactcc aagtgatacc tactggaaga aaatggaaaa
    16441 ttgcttcacc cggtaaccac aaaaaggcat tgacaccatt ccaaaacttc gagtgttcaa
    16501 cgattgttcc accaagactt tcaaactgga taccttcaag tacatttctg aatccaagga
    16561 tcaatccacc gacaatgatt gcaggaatca gtggtgtaaa gatttctgct aaaacggcaa
    16621 tagcacgttg aacgggatga aggttttgtt ttgcagctgc ttttccttgt tctttggaaa
    16681 ccccttcaac tccagatact gcaacgaagt cgttataaaa agtagaaaca tcgtttccta
    16741 tgatgacttg gaactgtcct gcattcgtga acatcccttt tacgctaggt atatcttcga
    16801 tcgctttttc gtccgctttt cctggatcat tcaggacaaa acgcatacga gtcgcacaat
    16861 gactaactgc agcaatattt tcttttccgc cgatatcatg taacagcttc tcggcatctg
    16921 cttgatattt tgccatatca ataaacccct ttctcttaac ttgtctatgc aagttgtttc
    16981 ttcatttact atactttttt tcggagagaa ttgcaagcgt tttattaaaa agtacgagag
    17041 aaaatgatat cgttttaaaa agcttaaaat aagcttttct taaaaatagg aacattgaaa
    17101 tacaaaaaga gctgtagtat agtgaagaaa tgatggaaga acgagtgagg gaaaaaacat
    17161 gaataagttc aatgaaattt ttttagattt ggaacagaaa attttagcga aagaatatcc
    17221 tccgcattcg cttttaccca gtgagaacca attgatcaaa atttatggtg tttcacgaga
    17281 aacaattaga aaagcgctga atcttttgac tacggaaggt tatattcaaa aaaaacaagg
    17341 aaaaggttcg atcgtactgg atcggaatcg cttcgacttt cctatttctg gattgactag
    17401 ctataaagag ctacaggaga cccaacgtat tccaagtgaa acgatcatcc atacgttaga
    17461 agaaacagaa gtgacaaaag cattgaacga gatcactggc tgggagatcg gtgcgcctgt
    17521 tttgcatttg atacgcgaaa gaaaaatcaa tggcgaagta gttatattag acaccgatta
    17581 tctattaaag gaaatcgttc ctattttaac tccagcacaa gcacaaggat cgatctatga
    17641 atattttgaa aatgagcttt ctttgacgat tgcttacgcg caaaaggaga tcacagtaga
    17701 agaagtaacg gaaatcatga aaacagcgat ggatcttcac gatgacactt atgcagtagt
    17761 agtcagaagc ctcgttcatc tggaagatac ccgctgtttc gagtattctg agtcggttca
    17821 ccgattagat aaattccgtt tcgttgagtt tgcccgacgc cgaaaagtgt aaatagttca
    17881 aaagaaagca aattgttggc atctgtccac tttggcgcta tgataggatc acaaaggggg
    17941 catttttaat ggataaacca ataagaccag aaaaagaaga actgaaagaa aagttatcac
    18001 ccatggctta tgcagtcaca caagaaaatg caacagaacg accatttagc gggaaatatg
    18061 atgattttta cgaaaagggg atctatgtag atatcgtcag cggtgaaccg ttattcagct
    18121 ctgcagaaaa atatgatgca ggttgtggct ggccatcatt cagcaaacca ataacgaaaa
    18181 gacaagtgcg cgaaaaagcc gatttttctc atggcatgca tcgaatagaa gttcgaagca
    18241 aagaagcaga ttctcatctc ggacatgtgt ttaccgatgg accagtagat caaggtggtc
    18301 tacgttactg catcaattct gcctcactga aattcattcc atatgaaaag atggatgaat
    18361 taggttatgg ggaattcaaa tcacttgtag aataatggaa atacacaaag agcggtacaa
    18421 tacggggatt tactcgatcg tccgctcttt ttttattcaa gcgattgcta tttgaaagaa
    18481 acgctcccta gactcctttt ttcacaaggt gaaatgtgct acaataaagg gaacgtatgt
    18541 gtgcaaaaga aagaggacta gaatatgtat gaatatctga caggtgtggt tacctttatc
    18601 aacccctatt acatagtagt agaaaccaat ggtatcggct accagatcgc actaggaaat
    18661 ccttaccgct acagtagcaa actaaatcaa aaaataaaaa tttatgtcca tcaggtaata
    18721 cgtgaagatg cgcatcttct gtatggattt gattcgctag aagaaaagca actgtttttg
    18781 cgattagtaa gtgtttcagg aatcggtccg aaaagtgccc ttgcaatcat ggcaagcgaa
    18841 gaccactccg gtttgattca agcagtagaa tccagtgatg tcacttattt gacgaaattt
    18901 ccaggagtag ggaaaaagac agcacaacaa atgatcttgg atctaaaagg aaaattcggt
    18961 gagctgagta tcgatacacc ttttagtcta tttgatgaag caaacacaaa agacgctaca
    19021 gctctatctg aagcaatgga agctctctcg gctcttggtt acagtgatcg agaaatcaaa
    19081 cgtgtagaaa aacaattaaa agaagtagat aatcagacaa cggatgagta tctacgccaa
    19141 gcactcaagc taatgatgaa aaaataagga ggagaccaaa tgacagatga atacttgtta
    19201 tcaccagaat ctggcgaaaa tgaactgagt ttggaaaaat ctcttcgacc acagctgctt
    19261 tctcaatata tcggacagag aaaagtcaaa caagaacttc agatttacat cgaagctgcc
    19321 agaaatcggg aagaaccttt agatcatgtt ctgttgtacg ggcctcctgg attaggaaaa
    19381 acgacgatgg ccatggtcat tgctaatgag atgaccgtaa atattcgtac gacgagtggc
    19441 cctgctatcg aacgtccggg tgacttagta gcaatcttga atgaactgga agcaggggat
    19501 gtcctgttta tcgatgagat ccatcgatta cctagagtgg tagaagagat gctttattca
    19561 gctatggaag atttctatgt agatatcatg gtaggacaag ggccaaccgc acatccggtt
    19621 catttccctc ttcctccctt tactttgatt ggcgcgacga cacgggcagg tatgctttct
    19681 gcacctttac gagatcgatt tggcatcatt tctcatatgg aatattatga cgaacaggat
    19741 ctgcaggaga tcgttttacg ttcttcggat atttttcaaa cagagatcat tgaagaaggg
    19801 gcattggaaa ttgctcgccg atcacgagga acgcctagaa tcgctaatcg cttgctcaaa
    19861 cgggttcgtg attttgcgca agtccaagga gacgggaaaa tcgatcgtcc tatagcggat
    19921 caggcactta ctttgctaca ggtcgatcag gctggattgg attatgttga ccagaaattg
    19981 ttgcgaacaa tgatcgagtt atatggcggc ggaccagtag ggttaagtac gctttcagta
    20041 aacataggag aagagcgtga gacggtagaa gatatgtatg aaccgtatct gatccaaaaa
    20101 ggatttttaa agcgtacacc tagagggcga attgctactg cttatgccta tgaacatttt
    20161 ggttacgact atcatatatg atttttgctt ttagattgga ggaaaatgaa tgagtgatac
    20221 aacacgtacg aaacaattga tcaaaaacgt attgattgat ttgtgccaaa cgcaatcttt
    20281 tcgaaaaatc agcgtccaaa aaatcgcaaa cgaagcaaaa atcaatcgac aaacatttta
    20341 ttatcatttt acagataaat acgatttgct tcgttgggtc tattgtgagg atgcattgca
    20401 ttatttagat ccacaatgtc tttcacttga taattgggaa gagcaagcat tgaaaatgct
    20461 gaaagcaatt gctgagaaga aagaatttta tgcaaatact gtgctttctg acccagaaat
    20521 tttacaaaaa gagttttctc aactgatcca aaaatcattt atcaagattt ttgaacaaat
    20581 ggatgaagaa agacaacttt ctgcaagaga caaactattt tatgctcgtt ttttttctta
    20641 cggttgcagt ggtgtattag tcaattggat cacgaatgaa tatgaagaaa caccgatgga
    20701 aatcgctatg cagcttttcc gtttagccaa ggatacggaa ttatattctt atcgtcttta
    20761 tgcaaaagaa gagttggaag aacagtaata gaaaaatttt ttgttggaaa agcaataatc
    20821 gctaaaagga gatggggaaa tgacaaaaat tttatttgtt tgtttgggaa atatttgccg
    20881 ttcaccgatg gcagaaggct tgctgagaaa acgaatagca ttagaaggaa gggaagcaga
    20941 attttttgtg gattctgctg ctacaagcac gtatgaagtt ggaaagacac cgcaccctgg
    21001 aacgaaaaaa atattaaacc aagaaaaagt agatatgacg aatatggttg ctcggcaaat
    21061 cacaccccac gattttgaaa cttttgattg gatcattggc atggatcaag aaaatgtaga
    21121 agaactgaaa cgaagagcac cacgctcagc gcaggggaaa atccatttgt ttttaagtag
    21181 cattcctgga aaagaaaaag aaaatgttcc cgacccatac tataccaata actttgatga
    21241 gacatatcac ttgatcacag aaggcctgaa tcattggtgg aatatttgga ttgatgaaaa
    21301 taaaataaca aacaatttgt aaagttaacg ctttcttttt aaggcgatgt tagagcattt
    21361 ccttgttttt ttgtaaaatg ttaggtaaaa taaaattaat taagtaacac tttcttagct
    21421 aaaggaggag tgcattcgat gaacgaagag acagtatcgc caatgaagaa gcttacgaag
    21481 ttagttactc atacttcgta tcaacttttt gattcttttg taaatgacac tgaagaacat
    21541 gctaagaatg tacgattgca aggaaagttt attcttgagc tgcaaaaagc tgctactgaa
    21601 catagtctag ttatcttaca agtaagagca aatcgtttga gtagcaagta tgaaacgatc
    21661 tcaggctggg tggcgacaaa aacggtcgaa aaagaccgag tgatgatccg cctacaaaac
    21721 gaagagcagc agatccggat ggttcctgta gaacaaattg aaaaaataac aatcctttca
    21781 ccagcagggg aacaggaacg gttatcaaaa taatttatac cagatagaaa agcacgtatg
    21841 agcttgtacc atcaatcatt actaatcaaa aataaccgaa tgctttaagc tgatatcagt
    21901 aaaacggaac gttttaggat gagtatcata gcatgacagc attcggttga ttagttgaat
    21961 cgattggatg gtacaagttt ttttgataaa aaaaggtcct gctagccggg gagctagcag
    22021 gataaggagt taaaaatgaa aaagtgttgt tagggttgtt tgttggtatg cttatataat
    22081 agtcattagt tgtgaatatt ttgtgacgaa agttttcgaa agttgttaag tt
//
LOCUS       DAFEIE010000041        21863 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFEIE010000041
VERSION     DAFEIE010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.042"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(46..705)
                     /locus_tag="LP345_001808"
     CDS             complement(46..705)
                     /locus_tag="LP345_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL1760587.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            1021..1965
                     /gene="mvk"
                     /locus_tag="LP345_001809"
     CDS             1021..1965
                     /gene="mvk"
                     /locus_tag="LP345_001809"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBL1760588.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            1958..2935
                     /gene="mvaD"
                     /locus_tag="LP345_001810"
     CDS             1958..2935
                     /gene="mvaD"
                     /locus_tag="LP345_001810"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBL1760589.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            2948..4033
                     /locus_tag="LP345_001811"
     CDS             2948..4033
                     /locus_tag="LP345_001811"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBL1760590.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            4030..5094
                     /locus_tag="LP345_001812"
     CDS             4030..5094
                     /locus_tag="LP345_001812"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBL1760591.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(5343..6146)
                     /locus_tag="LP345_001813"
     CDS             complement(5343..6146)
                     /locus_tag="LP345_001813"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBL1760592.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(6166..6915)
                     /gene="kduI"
                     /locus_tag="LP345_001814"
     CDS             complement(6166..6915)
                     /gene="kduI"
                     /locus_tag="LP345_001814"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBL1760593.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVCESCQLQMGYTILEPGSAW
                     NTMPCHTHERRMEAYVYFDYANEDTRVFHMMGKPDETKHLVVDNEQAIISPSWSIHSG
                     VGTSNYSFIWAMCGENITYTDMDMVQMDQLK"
     gene            complement(6931..7938)
                     /locus_tag="LP345_001815"
     CDS             complement(6931..7938)
                     /locus_tag="LP345_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL1760594.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(7945..8589)
                     /locus_tag="LP345_001816"
     CDS             complement(7945..8589)
                     /locus_tag="LP345_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBL1760595.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(8689..9447)
                     /locus_tag="LP345_001817"
     CDS             complement(8689..9447)
                     /locus_tag="LP345_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBL1760596.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(9574..10725)
                     /gene="fucO"
                     /locus_tag="LP345_001818"
     CDS             complement(9574..10725)
                     /gene="fucO"
                     /locus_tag="LP345_001818"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBL1760597.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(10807..11118)
                     /gene="rhaM"
                     /locus_tag="LP345_001819"
     CDS             complement(10807..11118)
                     /gene="rhaM"
                     /locus_tag="LP345_001819"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBL1760598.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(11120..11965)
                     /gene="rhaD"
                     /locus_tag="LP345_001820"
     CDS             complement(11120..11965)
                     /gene="rhaD"
                     /locus_tag="LP345_001820"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBL1760599.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(11979..13235)
                     /gene="rhaA"
                     /locus_tag="LP345_001821"
     CDS             complement(11979..13235)
                     /gene="rhaA"
                     /locus_tag="LP345_001821"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBL1760600.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(13232..14692)
                     /gene="rhaB"
                     /locus_tag="LP345_001822"
     CDS             complement(13232..14692)
                     /gene="rhaB"
                     /locus_tag="LP345_001822"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBL1760601.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            14845..15714
                     /locus_tag="LP345_001823"
     CDS             14845..15714
                     /locus_tag="LP345_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBL1760602.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(15840..16739)
                     /locus_tag="LP345_001824"
     CDS             complement(15840..16739)
                     /locus_tag="LP345_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760603.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(16904..17728)
                     /locus_tag="LP345_001825"
     CDS             complement(16904..17728)
                     /locus_tag="LP345_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL1760604.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(17739..19034)
                     /locus_tag="LP345_001826"
     CDS             complement(17739..19034)
                     /locus_tag="LP345_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBL1760605.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(19050..19529)
                     /locus_tag="LP345_001827"
     CDS             complement(19050..19529)
                     /locus_tag="LP345_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBL1760606.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(19535..20563)
                     /locus_tag="LP345_001828"
     CDS             complement(19535..20563)
                     /locus_tag="LP345_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBL1760607.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(20580..21686)
                     /locus_tag="LP345_001829"
     CDS             complement(20580..21686)
                     /locus_tag="LP345_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL1760608.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
BASE COUNT         6272 a         4850 c         3924 g         6817 t
ORIGIN      
        1 aagtcgctca aataaaggtt taccctttat ttgagcaact gtaaatcaaa tggctacttt
       61 ggtttggcga atctctgcta atttttcttc gatcattttc aagacttctt cttttgcttg
      121 aggatcttcc acaaaattat agcggtctcc atcgatttgg atttttggac tttctttgta
      181 ttcttcatac cattgatcgt aacgtctgtt caattctttg taataatcgt atagacttgg
      241 atcaaaggac aattgttcat acgaacgacc acgtttttcg atacgctcca acatcgtatc
      301 aaaagataca cgaatatgaa ctaataaatc cggatgtttt ttatgggcag catagggaag
      361 ttcttccatc atgttttcca gcagttcatc atacacacga acttctgttt ctgttgctct
      421 tcctagatct gcatttagat ggaaaagcag tgaatcttca taaatcgaac ggtccaatac
      481 attattgtca tctttcattg cttgtttgat gcttgcaaaa cgtttattca aaaaataaat
      541 ttgcagcaaa aaagcatact gttcagggtt tgcataaaat aagggcaaga cttcattatc
      601 atcaatcgat tcataaaatg cctgactatc aaagtgttca gccatcattt ctgttaaact
      661 tgattttccg gcaccaattg tacctgctaa aacgatcacg ctcatttacc tccagctcac
      721 ttcatcacta aatattgtgt ttaactccaa cctttttaaa tataccccca atatctagta
      781 gtgtcaattg tatttttttc tagtcaaaga agaaaaaaag tcaaaaaatt cttaagaaaa
      841 aagtgttttt tctttagaaa acgtattctt agttttactt ctgagatggt tttagtaaaa
      901 taaaggagga atgttttttg agacccttag tggacaaaaa aattcgtgaa gcagcgcaac
      961 tcgttttggg cgctttattt tttgcttaaa aatcactttt acgtgagaag gagttagatt
     1021 atggcaaact atggccaagg agaatcaagc ggaaagatca tattgatggg cgagcacgcg
     1081 gttgtttatg gagaaccagc gattgccttt cctttctatg caacaaaagt caccgcattc
     1141 cttgaagagc tggatgcaat ggacgatcaa ctggtttctt cctactattc aggaaattta
     1201 gccgaagctc ctcatgcatt aaaaaatatc aaaaaattat tcattcactt aaaaaaacag
     1261 catgacatcc aaaaaaactt gcaactgacc attgaaagca cgattcctgc tgaacgtgga
     1321 atgggatcaa gcgctgcagt cgccacagca gtcactcgtg ctttttatga ttacttagca
     1381 tttcctttgt ctcgtgaaat actattagaa aatgtccagc tttcggaaaa aatcgcccac
     1441 ggtaatccta gtggaatcga tgcagccgct actagcagct tgcagccgat ttattttaca
     1501 aaagggcatc ctttcgacta cttttctttg aacatcgatg cttttttgat tgtcgctgat
     1561 acaggaatca aaggacaaac aagagaagcc gtcaaagatg tcgctcacct ctttgaaacc
     1621 cagcctcatg aaactggaca aatgatccaa aaattaggat acttgacgaa gcaagcaaaa
     1681 caagcaatca ttgaaaattc accagaaacg ttggcacaga caatggatga atcacaatca
     1741 cttctggaaa agctgacaat cagcaatgat tttcttaatc tattgatcca aacagcaaaa
     1801 gataccgggg cattgggtgc caaattaact ggcggtggac gcggtggctg tatgattgca
     1861 ttagcacaaa caaaaacaaa agcccaagaa atcagtcaag cacttgaaga tgcgggtgct
     1921 gctgaaactt ggatacaagg attaggagta catacctatg tttaaaggca aagcacgcgc
     1981 atataccaac attgctctaa tcaaatattg gggtaagaaa aatgaagaac tcatccttcc
     2041 aatgaacaac agcctttcgt taacattgga tgcattttat acagagacag aagtcatctt
     2101 ttctgatagc tatatggtag atgaatttta tctagatggc accttgcaag acgaaaaagc
     2161 aacaaaaaaa gtcagtcagt ttcttgacct ttttcgtaaa gaagccggcc tctcactaaa
     2221 agcttcagta atcagtcaga atttcgttcc taccgcagct ggattagcct cctctgccag
     2281 cgggctagct gctttagcag gcgcttgcaa tactgctctt aagcttggat tagatgatct
     2341 ctctctttca agatttgctc gacgcgggtc tggttcagct tgccgaagta ttttcggtgg
     2401 tttcgtcgaa tgggaaaaag gccatgacga cttaagttct tacgctaagc cagtcccttc
     2461 cgattctttc gaagacgatt tagcaatggt tttcgttttg atcaacgacc agaaaaaaga
     2521 agtgtccagc agaaatggga tgcgtcggac agtcgaaaca tccagttttt atcaaggctg
     2581 gttagattcc gttgaagggg atctatatca attgaaacaa gcaatcaaaa caaaagattt
     2641 ccaacttctc ggagaaacga tggaaagaaa cggactaaaa atgcatggaa cgactttagc
     2701 tgcccagcct ccattcactt actggtctcc tgacagctta aaagcgatgg atgcggtgcg
     2761 acaattgaga aagcaaggca ttccatgcta ctttacgatg gatgctggcc ctaatgtcaa
     2821 agttttagtg gaaaacagcc atttatctga ggtacaagaa acatttacca aattatttag
     2881 caaagaacaa gtaattactg cacatgctgg tccaggaatt gcgattattg aataaaggga
     2941 gatttttatg attgaagtat ctgcaccagg caaactctat attgccggag aatatgcagt
     3001 tgttgaaaca ggccatccag cagttatcgc tgcagtcgat caattcgtga cagtcactgt
     3061 agaatctgca cgaaaagtcg gaagtatcca atctgcacaa tatagtggga tgcctgtacg
     3121 ttggacaaga cgcaacggag aattagtttt agatattcgg gaaaatcctt ttcattatat
     3181 ccttgctgct attcgcttga ctgaaaagta tgcacaagaa aaaaacattc ttttatcctt
     3241 ttatgatctg aaagtaacaa gtgagttaga cagttcaaat ggccggaaat atggattggg
     3301 ttctagcggt gccgtgaccg ttgcaacggt caaagccttg aatgtttttt acgcgttgaa
     3361 tttatctcag ttggagattt tcaagattgc agcactagcc aatttagcag ttcaagataa
     3421 tggttcctgc ggcgacatcg ctgctagctg ttatggtggc tggatcgctt tctcaacctt
     3481 cgaccatcct tggctccaag aacaagaaac tcagcattct atcagtgagt tacttgccct
     3541 ggattggcca ggtctatcca ttgagccatt gattgctcct gaagatttac gtttattgat
     3601 tggttggacg ggtagccctg cctctacttc tgatttggtc gatcaagttc accgttcgag
     3661 agaagataaa atggtggctt atcagctttt cttaaaaaat agtacagaat gtgtcaacga
     3721 aatgatcaaa gggtttaaag aaaataatgt aacgttgatc caacagatga ttcgaaaaaa
     3781 ccgacaatta ctgcatgatt tatctgcaat cactggggtc gtcatcgaaa cgcctgcttt
     3841 gaacaaattg tgtaatttag ctgaacagta tgaaggagcc gcaaaatctt ctggtgcagg
     3901 tgggggcgat tgcggaatcg taattgttga ccagaaatct ggcattcttc ctttaatgag
     3961 tgcatgggaa aaagcagaaa tcactccact gccgttacat gtctatagcg atcaaagaaa
     4021 ggaaaaccga tgaatcgaaa agacgaacat gtttcactag ctaaagcctt tcatgataaa
     4081 caaaaaaacg aatttgactt cgtacggatc atccataacc ctttgccgca aatagcagtt
     4141 tctgatgtcg atctaagtac acaggcagtt gggtttacac taagcagccc attttatatc
     4201 aatgcgatga ctggcggaag cgaaaaaaca aaaaaaatca accaagatct tgcaatcgtc
     4261 gcaagagaag cagatttgat gattgccact ggttcagtca gcgctgcctt gaaagtccct
     4321 tctttagccg atacttatac gattatgcga caagaatatc ctcacgggaa aatcattgcc
     4381 aacatcggtg cagggacttc tgtcgaaaga gccaaagaag ctatccgatt gtttcacgca
     4441 gatgccttac agattcattt gaatgcacct caagagttgg ttatgcctga gggagaccgt
     4501 gattttacca attggaaagt acttattcaa gaaactcaaa cagccattga cgtccccctc
     4561 atcgtaaaag aagtcggttt tggcatgaca agagaaacgc tcaatgatct agctgcttta
     4621 ggagttcata cagttgatat cagcggtcga agcggaacaa gcttcaccca gatcgaaaac
     4681 gcccgtcgct ccaagcggga actgagttat ttagctgact gggggcaatc gacagtctct
     4741 tcattgcttg aagcaaatga agcagacact tctatggaaa tcctagcctc cggaggtatc
     4801 cgcaatgcct atgacatatt taaagccctt tgtctcggcg caaatgccgt gggtacttca
     4861 ggaaccgtac tgacgcatct gatgaatcac ggcgtagaag aaactattat actgatgaag
     4921 caatggcaag aagagcttcg tctgctttat actatggtcg gcgcaacgaa taccgcggcc
     4981 ctacaccaac aatctctgat cttttccgga ccagtgaagg attggtgcga agcaagaggg
     5041 atcgacttag tgaagtatgg aagacgcaca gaaaagagcg tgggacaaaa gtaaagaaca
     5101 cttttgtctc acgctctaaa cacgtacaaa cggcggaagt aaaagcaact ccttcggaaa
     5161 taagctgaaa ttcacaaaaa tttgaaaagc aattttcgtg aattccttct tatttcttgg
     5221 agttaaatgc ttctgtccca gcctcttttt tcgaataaat gatgtttaat cagctgtcct
     5281 tcggtattcg ttcaatccgc tgatttcaca acctctccac taaacagtgt actaaagctc
     5341 ttttaaggtt gttttccgat ataggcaagt atgcctccgt ccacatacaa gacatggccg
     5401 ttaacgaaat cagatgcgct agaagccaag aagacagatg gtccagccaa atcgattggc
     5461 tcgccccagc gtgctgctgg cgtacgtcca acgataaatt gatcgaatgg atgacgttca
     5521 ccgttttctt gtgtttcgcg taatggagca gtttgcggtg tagcaatata acctggtcca
     5581 attccattac attggatatt gtattgaccg tattcagaag cgatgttttt cgtcagcatt
     5641 tttaatccgc cttttgccgc agcataagca ctgaccgttt cgcgtcctaa ttcactcatc
     5701 atggagcaga tattgatgat tttaccgccg cctttttcga tcatatccgg aataactgct
     5761 tttgaaacga tgaatggggc atttaaatcc acgtcgatta cttggcggaa gtctgccgca
     5821 tccatttcga tcatcggtgt ccgtttgatg atccctgcat tgttgactag aatatcaact
     5881 gaacctacat cttctttgat ctgttgaacc atcgcttgaa ccgcttcttc atcggtcaca
     5941 tcgcagacat aaccttttgc atcgatgcct gcttctttat aatgcgctat accttcatca
     6001 actgattctt gattcaagtt attaaatacg atttttgctc ctgctgtagc taaagagcgt
     6061 gcaatctcaa atccaatacc atagacagca ccggtgacta atgctacttt tccatctaaa
     6121 cgaaacatat ccatactaaa ttccatcatt ttctctccct tatgcttatt ttaattgatc
     6181 catttgcacc atatccatgt ctgtataggt gatattttct ccgcacattg cccagatgaa
     6241 tgagtaattg cttgtaccta cacctgaatg gatcgaccag cttggcgaaa taatggcttg
     6301 ttcattgtct acaactaaat gttttgtttc atctggtttg cccatcatgt ggaacacacg
     6361 tgtatcttca ttggcataat caaagtagac ataagcttcc atacgacgtt catgtgtatg
     6421 acaaggcatc gtattccaag cgcttcctgg ttctaaaatc gtataaccca tttgtaattg
     6481 acagctttcg catacatttg gatatttatg atgagctgga acagaactaa tatagaattt
     6541 agctgggttt tcagcatctt gagaagaaaa tacaacatgt cgtgtttctt ttccgatata
     6601 gtatccgtct tgttttttca tttcttcttt ttgcccatcg atctcgatga atcctggtcc
     6661 accgatattg atcacaccta gttcacgacg ctctaagaag taatcaacac ctagttcttt
     6721 gtctaatgtg atttctaatt ctttttcagt aggtgtcact ccaccaaaga tcattcgatc
     6781 gttgtgcgta taagtcaaac tgattttccc tggttcaaat accttttcta ctaaaaattc
     6841 ttttctcaat tgttccgttg aataatgacg gatatcttct ggactgtgtg tataacgtgt
     6901 ttccatttct tgcattttct tctactcctt ctatcgaatg atttttccag agccgcatgc
     6961 taaaaattgt gcgacttctt cttgactaaa ttggttgcag tccccatgga tcgtatgctt
     7021 caaggcagaa gctgccgtag caaaatcaat gatttcttgc ggagacatat tggataaaat
     7081 cccatggagc acgccacctg caaaagcatc tccgccacct actcgatcca cgattggggt
     7141 gattctatgg acttgggatt ccacatattc atggttcatc cacaatgtcc ccttcaattc
     7201 attttcactt gctgaatgaa cggtacgctt ggtcgaataa aacacctgaa tattcgggaa
     7261 cttttcctgc attttttgat aataataaat tagaggttgt tcttctgctt ctggcgcttt
     7321 ctcgatacct aacaaataaa gagcatccat ttttccagct gagcagatat ctactaaagg
     7381 taaaagctga tggattactt cgctggcttc ttgctgtgtc cataattttc cacgatagtt
     7441 gatatcgaag ctgatcaggc agccagcttt ttttgcagct tctatcacct gtttcgtcat
     7501 tttttgccat tttttagaca aagctggggt gattcctgaa acatgaaata tatctattcc
     7561 ttggaataac tcctctagcg accattccaa atgatccatt tcagcaaaac ttgatccggc
     7621 acgatcatag atcactgagg cggcgcgttc gccactacca gtttccatat aataagtacc
     7681 tagtcttgat ccaccagata atacctgttt cgtatctact ccataacatt gcaagtgctt
     7741 tttgactgct tttcccaatg cgttatcagg tacttttgta gcaaaaatcg cttcatgtcc
     7801 gtaattagct aaagaaattg ctacgtttgc ttcccctccg ccataatggg cagcgaatcg
     7861 ttcacttgaa tcgatacggg ttccctgctc tgtggacaat cgcaacatga tttctccgag
     7921 tgtcactact tttcccataa gcagctacct cttgatttct ttcatttttg ctgcatactg
     7981 ttgcgcgact tccgttactt tgtcaaaatc tcctgtagct gcgggtgcta aaaggttccc
     8041 acctactccg actgttacga caccagcatc gaaccactct ttcatattgt ccagactcac
     8101 accgccagtt ggcatgatat tgacttgagg catcggcgcc ttgaaggcag aaatgatact
     8161 tggtccataa gcgcttccag gaaatagttt gacgatatct accccgcttt tcagcgctgt
     8221 tttgatctcg gtaatagtca tacatcctgg taagtaagga atttgataca gattgcacat
     8281 ctctgccgtt tcttgatcaa aggaagggct aacaatatac tctgcgccag ctaagatagc
     8341 caagcgagct gtgacagcgt ctaatactgt gcctgcgcca atcactattt ctggttggtc
     8401 tttgtagaat gacaaaagtt ctttgattac ttgatctgct tgagggactg taaaagtcaa
     8461 ctcaatacca gttagaccac ctttgatgat tgcgtggcaa gcattcaaag cttcttcttt
     8521 gctttttccg cgtaccaccg caatcactcc ggcgtttttc aatcgagata aaatatcaat
     8581 ttttttcatc ttctccacct atttcctatt tagaaatttt attttataac ttggaaatct
     8641 atacccatat tatacggcag aaaagaaaaa ttgcaaacgc ttttttcatt atttttgaat
     8701 tctttgctcg atttcgcttt ttgtttgctt gagggcactg attatttgtt cttttgtctc
     8761 atctgttaaa cgatatttcg gcatacttac actaaatgca ccaatgattt gttcgttttt
     8821 cacgattgag gctcctatac aaaaaatatc acgttcgatt tcttcatcgt caaatgcgat
     8881 gtgggtttct tttaccgttt ggatttcctt tttcaaccgt aatgcattgg tgatcgtata
     8941 ttctgtgtaa gggatcaacg gatgcttttc aagataatca gtgtactgct cttcactgaa
     9001 ttctgctaat acggctttgc ccatcgcaga attgtataat ggtcgggtga ttccgatttt
     9061 tgaagacatg cggatcgttt gatgttttgg atctagtttg ttcacgtaca agatctcatt
     9121 gttgtccaat acccctaagt ggatagtctc atcgatcttt tgctgcagct gttctaaaaa
     9181 cggtaaagtc aactctacca aatcgatttg ttcaatgttt ttattcgcgt agcgaataag
     9241 ctttgcacct aaacgatagt ttttctctga atttttattt acgtagccga tcatcaacaa
     9301 agtatctagt attttcaaga ctgtagaaga ggtcattccc acaccctttg cgatcgtctg
     9361 caaagagaca tcttggtttt ccgctaaata gtctagtatt ttagaggctt tgatcaatac
     9421 agttccataa ggctttttat tttccatata atattctcct atttctttat aagaaaaatt
     9481 atagcggaaa taccatcaat ttaaaagaga tatccagata taaactacca tttctcttta
     9541 caggcaattt aatgttgaag atccgcttcg tttttacatc aaactttgat ataaagcaat
     9601 gatttcttct actgtcgttt ctcttggatt tcctggtgtg catacatctc gcaaagcatc
     9661 ttctgcaatt gctggaatat ctgcttcttt tacacctaat tcagaaatgg tttctgggat
     9721 tccaaccgct ttgctcaacc gatcgatctc accacaagcc gcttctctta catcttctaa
     9781 agacatttca gctgctcctt taatccctag aacaagagcg atctcacggt acttttctcc
     9841 agtatattct ttgttatatt tcatgacagt tggcaaaagt gctgcacacg ctacgccatg
     9901 aggaatgttg taccatgcac ttaacgggtg agccatcccg tgtaccagtc ctaaaccgac
     9961 atttgagaag cccattcccg caatatactg tcctaatgcc attttttctc gcccattttg
    10021 atcgccatct acagaagctt ccaaagaatg gccgatgatt tcgattgctt ttaaatgcag
    10081 catatcagtc atttcccaag cgccttttgt gataaaccct tcaatagcat gcgtcatagc
    10141 atccatacct gttgatgcag ccaatttttt cggcattccc atcatcatat cgctgtcgat
    10201 gaacgcgacg attgggatat catgaggatc aacacaaaca aattttcggt gatttacttc
    10261 atctgtgatg acgtagttga tcgttacttc tgctgctgtt ccagaagtcg ttggtatagc
    10321 taatataggt aaacatggat ttttcgtatc agcaacacct tctaaactaa tgacgtctga
    10381 aaactctgga ttcgtcaaaa taatcccaat ggcttttgcc gtatcgattg gcgaacctcc
    10441 accgattgcg atcaaacagt ctgcctctgc ctctttaaca aaagccactc catcttttac
    10501 attttggatc gttggattag gtacgatccc gtcgtataaa gcataagcga ttgctgcttt
    10561 atctagaagt tctgttactt ttgttgctat accgtgctcg atcaatcctt tgtcagtaat
    10621 gacagctgct ttgccgaatc ctcgctgctg aaattcaggg acgatcgact caatcgctcc
    10681 ttttccaaaa tacgatgttt catttaaaat cattcgatta ctcattttct attcctccta
    10741 atttgtatta tttttcacaa taaaaacgaa agaaccccaa gcaaccggtt gcccagttgc
    10801 ttgttgctac agttcaaaga ctggcatcaa ttcccaactg actggagagg catctggatt
    10861 tgtctccatg atatcttcca tgtacttcca ccatttttga ttgatagatg tatttgccat
    10921 tttttcccat aacttttcat cttcgatcac taagtaacca aataacaaac ttgtactcgg
    10981 atcaagatag atcgaatagt cgatgacccc gtgttcacga agtgctgtac gcatttctgg
    11041 ccaaagttca tcatgtcttt ttttgtattc ttcttgtttt tctgggtaaa ctttcatgca
    11101 aaaagctttt ttcaccatgt cagacacctg ctttcgtatg aacttcctcc aaataacctg
    11161 cttttggagt gacaccaaac gcatctgcta aatgccacag gttttcgtcc gtgattgttt
    11221 gcaagattgg tccttgcgct ttgacgtacg tatagacttc tgctgccttt tctgctgtct
    11281 cgatcaaacc aaagacttca tccatgtctt ttcctgaccc gtagattcca tgttgtggcc
    11341 ataaaaccaa tcgagtttct ttcatttttt cagctgttgc ttccccaatc tcatttgttc
    11401 ccggaaccat ccacggaatg atggaaattc cttctggaaa aacaactaag cattccgtac
    11461 acatttgcca tagcgtacga ctaaaggaac gttcgtctaa ttcatgcgta aaactcatcg
    11521 ctaatagatg actagcatgg caatgcataa cgatccgatt atctgggtct acttctaaac
    11581 gggcgatatg actcatgaaa tgacttggca actcgcttgt aggaaggcat tcgttttcca
    11641 gcccccacaa aagttccagt gttttgccat cttcagcaac tcgaacgatt ccaagattct
    11701 cggcaggttc gctcgctaca tttttaaaat atcttcctga accagttaca ataaaatagc
    11761 atcctgctaa acggctggca tcaaaaatca tcgagatgcg gcggatcact ttttcaggat
    11821 ccaagaacgg tgtgatctct tcttctttta gtaaataaga aatattcccg ccatttcttt
    11881 catcccatcc caagcgataa agattcgacg tcgtttcgat catttctttc acataaggcg
    11941 cttgtaaaat atctattttt ttcaatatag ccacactcct attttcttaa ttccaacacg
    12001 tctttttgat attcctggac ttcttccagc caatccaaac caactggaac ttgatttttg
    12061 taacagaaat aattccatac atcggcatac gggaaatctt tcaattcttc cgtataagcc
    12121 attcttgaag taaagtcaaa agccagctcc atttctttca atcgctcaac tggttccagc
    12181 atagctttca gcagtgcttt ttgtgtattt ctcgtaccga tgacccaagc agcgatacgg
    12241 ttgatcgttg catcaaagaa atccagaccg atatttgttt tttccaacaa ttcgttacgg
    12301 actaattctt tagcgatttc ctgcaattca tcatccatca aaaccacatg gtctgaatcc
    12361 caacgcactg gacgggaaac atgcaacatg attcctttgc tgaataaagc taatgaagat
    12421 aatttattgg aaatcacttc tgttggatga aaatgtccag catctagaca aacaagtttg
    12481 tcacgagtca acccgtaacc catataaaat tcatgggaac cgactgtata agcttcagcg
    12541 cctaaaccaa atagtttgct ttctactgca tcttgtacat accgttcatc taactcttct
    12601 gtaaaaattt catcgagtga ttccattaaa cgttcccgtg gggtaaaacg atcaatcgga
    12661 ttatctttca tcccatcagg tacccaaaag ttattgatac ttgtttgccc agtttctttc
    12721 ccaaagtact ccgcgatttt gcggcttctt ttcccgtgtt cgatccagta ttcacgaact
    12781 tctttatctg gatgagccaa tgtaaagccg tctttcatca ttggatgcga aaagaaagtc
    12841 ggattgaagt caagaccgat ttcttctttt tttgcccact ctacccattt ttcaaaatgt
    12901 ttcggctcaa tttcatttag atcgacagat tcttctgtat ccaaatagat agcatgaagg
    12961 ttcaatttgt gtttgcccgg tatcaacgaa taagccttct ccagatcttg tctaagctct
    13021 tcaggtgttc gtgcggctcc tggaaaattc cctgtcgcca tgattccacc ggtcaattcg
    13081 ccatccggtg tcaagaaacc tttgacatca tctccttgcc agcaatgcat agaaattttg
    13141 atgtcctgta tcttttctag tacagcatct gtatctacac cgatagttgc atatttttct
    13201 tttgcttgtt cgtaatttct ttcaatcgtg ttcatacgat tactcctttg attttattca
    13261 cgtaccattc catcgtgttt tgcttatttt catctgggta aaaagtttca catggaaacg
    13321 actgtttgat tacatttctt gcttgttcta tattcgaaaa ctgacctgta ctgagcattt
    13381 gcatggcaac attcccgatt gctgtggctt cactaggtcc tgcttctaca atgattccgg
    13441 cataatctgc tgtcaattga ttcagtagac gattattcga tccgccccct acgatgtgca
    13501 gcttttccaa tttcgttcca gttaagtgtt ctactttgat cagctcttgt gcgtaacaaa
    13561 gagcaagatt atcatacaca caacgagcga tagctcccga tgagacaggg actggctgct
    13621 ctgtttcaaa acagtattgc tgaatctctt ctatcatatt tgggggattc aaaaatcgag
    13681 ggtcattgat ttccatcact tgctgcagcg gtttttcttt tgcagcaagc tctgccaatt
    13741 ccgcataact gtactcgtac tcttgcattc gggcaacttc ctggatcaac cacatcccca
    13801 tgatgttttt caaaaaacgc accgtgttat gggcacccca ttcattcgta taattttcag
    13861 aaaaagcatt gcgagaaaca ttggcgatct ttgtttcaat ccctaaaagc gaccatgtcc
    13921 cactgctgat ataaccccaa cgttctcctt gacctggcgt tcctaataca gctgacgccg
    13981 tatcatgact tgctactgtg ataaaggtca catctggcaa atcatatttt gaaaattgtt
    14041 ctttttgcag atctcctagt atcgttcccg gctctgtcaa tggtggaaat aattccttcg
    14101 agacaccgat tttttcaaga agttctattt cccattcttt tgtccctgca ttcagcagct
    14161 gcatagtaga tgcattagtt ttctccgtca ccatgttacc agtaaagaca taccctaaat
    14221 aatcaggtat cagtaacaat ttatgtgctt ttgccaaatt ttctttttct tcagcaaaca
    14281 attggaacaa ggtattgaaa ggctggatct gaatccctgt ctgctcatac aacttatcta
    14341 gagaatagat ttcagaaaac tgttctactg ctccattggt acgcttgtcc cgataagcaa
    14401 tcggatcatt tatccgatcc ccttgttcat caatcagaca gtaatcgact gcccatgtat
    14461 cgatccccgc aaaaaggcga tcaatccctg tctgctttaa tttttcaaat ccaatcaaaa
    14521 tctctttgat aagataatcg atcttccagc gatcgtgacc gtctttgttc cgaaagccgt
    14581 ttttgaaccg gtgtacttct tccaagatca aagaaccttt tgcatccctc gtacttttca
    14641 ttagtcgtcc gcttgatgca ccgatatcga tggcaacaaa tgttggattc atttctccac
    14701 ctcttttact ttattgttga ttagcacttt attaataaag cgttatcatt tattaacaat
    14761 gctatcataa tacagaatct tatattttgc ttcacactat tttggtatat aattgcatta
    14821 tcttgacaag ttgggagtgt ttacatggat tactgggaaa aagccaacca ctcatggtcg
    14881 gaagactcaa aaagagtgat cttgacgcct acacaaagaa gcaggaattt atttttttat
    14941 atccaagaaa tcggttactt caaagcacca atcccttact atactgaacg agcacattta
    15001 ccttcttact tgataaagtt tactttgtct ggcaaaggtt cgcttacata taatgataat
    15061 cagcaacagc taaaagctgg agacttattt tttattgact gccaagaata tcagcgttat
    15121 caaacgatca gcgaagaacc atgggaaatg gattggatcc atttgaatgg tcagaacgtc
    15181 caatcatttt atcaggagtt cacaaaagac ggccataaca ccttccattc aacaggggat
    15241 ccatcagaaa acaagatcca ccatttgatc acagaattga tccacatgca acaaggcacg
    15301 aatgcccgta ccgatttcca gtcctctgta gctatccacg agttgctgaa tgaactgatt
    15361 ttgcaaaagt atcagctaga tttcgaagaa gaggatattc ccgcctacgt ttacaaactg
    15421 aagcaatact tagacgaaca tttcaaagaa acgattacac ttgatcaatt agaacaacaa
    15481 ttcttattga ataaatatca gctgagcaaa gatttttcca aatttatcgg ttctccacca
    15541 atcgattatt tgatcagcaa aaaactttct tacgctaaag accttcttcg gtatacagaa
    15601 tttacggttc gaatgatttc cgaagaaata gggattgaga attttgctta ctttagccgc
    15661 ctgttcaaag caaaaacagg actatcgccg agagactttc gtaaattcag ctgattcata
    15721 taatatgtac gtcatttttt caaaatattt tgaaatatat agataaaaat aaaataaccg
    15781 cagtttctgc ttctatgtaa acaacagcag ctactgcggt tattttttag tgatcattct
    15841 cattgttcat cttcaaaatg ttcataatga accaactgtt tctgtgtatc acgtttcaaa
    15901 aattctttag gcgttatgcc gaactctctc ttgaatgctt tcagaaaatg cggataagaa
    15961 gaaaaaccac ttttactata tacagcacta gagctgcggt attctcgcaa caagtgcttg
    16021 gcatagatca gctttttctt cattacatac tgatgaaacg taaatccagt gtacttttta
    16081 aattctcgtg tgatatggta tttgctgaca aaaaactgct tttccatttc ctctaaagaa
    16141 agcggatgag ataaattttt tgagatatat tgtaacattt gttccacacg ctcattagga
    16201 actacagcat tctgttcttg cgcactctct tctttttgta caacttgatt gagaaaaatc
    16261 aagtattcta ccagagcttg ttcatatttt atgtcttcac cgtaaatttt tttatcagga
    16321 ggatggtcga taaatgataa tttttgcttc aatacttcct gttctatttg caatacacga
    16381 ctcctcttct ctcccattgg ttgaaagcaa gccgatagat tagaccatgg cgtggaacga
    16441 ctttctagaa aagaaggggt gacaaagata tagacacgct cgaatacatc tgaagattgg
    16501 cggacgatac gatgcaaatc attggaatgg atgagcagca cacttcctgc tttgatcgta
    16561 aattgtcgtc cgttcaaata aaaagtcgct tctcccttta atgtagcatg gatctcatag
    16621 aaatcatgat gatgatagat cgttttattt tggctgacga catctttgac atgatagatt
    16681 tcatactgat cagaaaccat cgtattgact tgttcaccgc tgattttctt ttggagcatg
    16741 tgccgcacct ccttttgttc acttatgcac aattttatta taccacgttt tttgtaatca
    16801 aaaagagctg cttttatata ctcttataaa aaagaagaga cgtggcatct tctagccccg
    16861 ccccctccat tctaaatatt agttaaccaa cgtcttcttt acattattca agaagacttc
    16921 ttccataacg aatcccatca tcttttgttt cttcaagaac cacatacagg tacggacgat
    16981 tcttcatgat gatttctttg atttttgtgt actcgatcac accgtctccc aaatttaccg
    17041 gcacgatttt ttcctgttcg acacgaaaat ctttcaaatg aaccgcacat atcttttcac
    17101 caaaacgttc aaaagcttct tctaccaatt ggacttgttc ttgataatca ctacttgtga
    17161 tcaaattggt cggatctaaa atgattccta gatagtccga atctactgct tggatcagct
    17221 gctctaccct tgctaaagaa tacaccggat gattcaaacc tggttctatc cccaccatca
    17281 tttggtattt ttctccagct tttaccaagc gacggataac ggacacagct tcagcaaatg
    17341 cttcatctgt gaaattttct tccgtatatt ggatttccgg caaaacacat ccagtttccg
    17401 aagcaaccat cgacgcacca aaggaagaag catagcgaag atactgctcg aactttgtca
    17461 gcaactcttg tcgtatcgtt aaatctggat gaatcatatt gatatagcaa cttaaaattc
    17521 ctacggtcac ttcttgcttt tctaaaactc gtttgacata atttcccatc ccagaattga
    17581 tctcatttgc gccagaaggt atttcaggaa acgaaagacc taaggcgagc tgcagtgtat
    17641 gaatcccttg ttcttttgtt ttttctgcaa gatcttctat cgtttggact tcggaaagat
    17701 catgtcctct aattgtaatg ttcaacataa ctattctcct aactcagcat attgggtagc
    17761 cacatgacga tttgcgggaa gtaagtaatc aaaaacaaga cgactaagat aaccccataa
    17821 aaaggaagaa gcggtttcag cattgcctct gcttttacgc ctcctacact tgcaccgaca
    17881 tatagtcctg tacctactgg cggcgtgatg gagcctacac acagattcat gattgaaaac
    17941 aacccgtaat gtacaggatc aacccctaca cttgtgacga ttggtaaaaa tattggtgta
    18001 aaaatcaaga tagcaggcgc cacatccata aacataccca ccagtaataa cacaagattg
    18061 actaataaca gaataataaa tttattatcc gttacgccca taatcaacga actaattgcc
    18121 tgaggaatac cggtaaacgc catggcgaaa gacatcatgg aagaagtagc caataagaac
    18181 atgatcgtcc ctgacattgc tactgattga aacaacatat taggtatatc ttttagtttt
    18241 accgttttat agtaaaacat agcaatcaac agggagtaaa tgacagctat cgctgaagct
    18301 tctactgcag taaatatccc cgtcaagata ccaccgataa tgatgacaat caatagaagg
    18361 ctaggaatcg cctcttttat tatttttcca gcatgagcca tctgtccttt ttcgacaaca
    18421 gggtatttat tctttttagc aacgatgaat gctactagca tgattcctag cgcccacaaa
    18481 gcgcctacga gataacctcc cataaacaaa gcagagatcg aagcaccacc agcaacaagt
    18541 gaatacatga taaaagcagt acttggagga atgaccatac ctgtcggagc tgacgcgata
    18601 ttgaccgctg tcgcaaactt ccggtcatat ccttcttcca cttgctgagg gatcaacact
    18661 ccgccaatcg cggtagaagc ggcaatggcc gagctagaga tggaaccaaa taaagcattc
    18721 cctaacacat tcgtatgagc caaagccccc ggcacgcgcc cgacgaacaa catcgcaaaa
    18781 tccactagtt tcttagctat ccctccatta ttcatgataa tgcccgagag aacgaaaaac
    18841 ggaatagcga tcagcgaaaa actattgata cttcccacca ttttttgagc tgaactaaaa
    18901 gcagaaacat caaacggtat aactaacaat aaagtcatca tcgatgagaa tgcaatactt
    18961 atagcaatcg gcatccctaa tacaagcaac acaacaaata caaaaaataa cactaatccg
    19021 gcttctattg ccattttatt cctccatttt tatatttttt cttgaattgc tggcttgttg
    19081 cttaatgtat cgattagatt gatcaggcta tagataatga tgagtacccc cgatacaggt
    19141 actgacagat aaacatatcc cataggaata cttaaagaag gcgagatctg ccccattgtc
    19201 aatgtgacag cattccatcc gccatacacc atgatcatcg cagcaaatac cagaaataaa
    19261 ctttgaacaa caacttctaa aattttactt tttttgccag ttaatttttc acttaaaacc
    19321 gttacggcta aatgtgcttt ttgtcccaca acatacgcgg aagacaacat ggcaaaccag
    19381 acaagaccga atcgaacaag ctcttccgtg accgtatttg gatttcctaa aaccgttctg
    19441 gaaaatactt gccataaaac aacagcgacc atcccaacaa gcaaaacagc tcccaggatc
    19501 tctaatacct tgtttaaaat cattttcatc acagctacgc tccttgctct tggatctttt
    19561 gataaaggtc tttgtaggta ggatcgtttt tgaatatatc atgaagtggg gcaactgcct
    19621 ctcgaaacgg tgtattatct acatcattga attggactcc atgttcttct tgtgctaaag
    19681 ctttttcttc ttcaattgct tttgcaaaag cttcaatttc aaaaaccgtt gattctttcg
    19741 ctgcttcttc aatggctttt tcctgctcat cagttagctg ttctttgatg gcatcattca
    19801 tgatgatgat atctggcaca cgtgtatgct catcatagga atagtattta gccacaccac
    19861 catgtccagc tgtatacaag acaaattcat tgttttctga tccgttgatc aaattggatt
    19921 gaagagacgt gtacacttca tcacttccca taggtacggg cgaaccgcct aaaagctcta
    19981 ccattttgat agcggtttcg ctttgcatca cacggatctt ctttcccttc aaatcttccg
    20041 gcgtatggat cggaccgtct accatataaa agctgcgctg accagaatca taataggtca
    20101 atccggtaaa tcctaaattt ttggtcgatt ggtagattgg ctccattatt tcttcattat
    20161 ccatcacctt aaagaaatgt tcttcatcat tgaatagata aggaactgaa aaaatcgaat
    20221 aatctttaga gaaactttcc aacgctgagg cacttacttt tgtgaaatct actgctcctg
    20281 actgtgtcaa ttcgatcagt tcacgttctc cacccagttg tccatctggg aaatactgga
    20341 tctgtacgga accatctgtt ttttctttta ctaaacgccc aaattcattc attgcatcaa
    20401 ttactggctg gctgttgctt gcataagcaa agcgcaaggt aactatctca tttacatctg
    20461 catctgcgac agttgccaca ctagaattat ttccgcagcc gcttagacct agcagaccta
    20521 ggctaagcga acttgctgca aacagcagtg atgttttttt catatgggtt tcctttcttt
    20581 taacaataag agacgagcaa ttctgtcaaa caaagcaccg ttaacgactg tccataaggc
    20641 attgctgtga ttccgatatt ccgataaaaa tctaaactgt cccccattcc tgtcccgatt
    20701 gaaacgtttt gaacttctcc tttttcatcg atttgttcaa gcaatccttg gatagcacga
    20761 taagcgactt ctttatattc ttgtggtaaa taacgtttat ggaccgcttt caaaataccg
    20821 taagcaaatc ctgcagttgc agaagattct acgtaagaag aaggatcatc caacaacgta
    20881 tgccataaac cgctttcaga ctgataagtt tttaatgcac gcacttgtgc ttcaagtgtt
    20941 tcgatcaata atttgcgcaa tgcatcttct ttcgataatt ctaagatttc aatgatctct
    21001 ggaatagcaa tcgtcaacca gcagtttcca cgagcccaaa atgcttcggc atagttatga
    21061 tttccttcaa acgtccagcc gtgataccac aatcctgttc gtttatccat caagtatttg
    21121 atatggatca taaactggta acgagcttct tctaaatatt ctgggcgatt caacagtttc
    21181 ccgatttttg ccaaaggaag cactgtcatc atcaatgtat cgtcccacaa ctgattctta
    21241 ttttccggtc catatgtggc atgctgtaac ccgtcttcat ttgtccgagg catgtcattc
    21301 atgacccatt ctgcccattg ttctaaataa ggcaaatagc gtgaatcttt cgtgtcttca
    21361 tacaagtaag ccatagtcaa tagcggtgcc attgtattga cgtttttggg cggagcgcct
    21421 tcttccatac gatcctcaaa ccattcattg accacttgat aagcgcgagg attttttgtc
    21481 atctggtaat ttttataaat accatataga ccgacacctt gtggccaatt ccacactgtc
    21541 cagcttttgt catctacttt cagtccatca aagtccaaca aaaattcacc attatcgtct
    21601 ttgatcgttg tcaggttttc aacgagcagg tcaatttttt ctttcactaa ttctttaggt
    21661 acaaaaatct cttctttaat aatcatcttt acgccacttt tttaaacgct ttcattttat
    21721 atccttaata tagcagtaat accgtccact ataaatatcg ctttttgaac aaaaactgtc
    21781 taaaattgac ctaaatgtta aataacaaaa gtaactttca gttacttgga aattaaaaaa
    21841 agaacttgga gaaacaacgt ttt
//
LOCUS       DAFEIE010000042        21500 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFEIE010000042
VERSION     DAFEIE010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.043"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            2..400
                     /locus_tag="LP345_001830"
     CDS             2..400
                     /locus_tag="LP345_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL1760609.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="LP345_001831"
     CDS             384..1079
                     /locus_tag="LP345_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBL1760610.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1663..2550)
                     /locus_tag="LP345_001832"
     CDS             complement(1663..2550)
                     /locus_tag="LP345_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL1760611.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2735..3574
                     /locus_tag="LP345_001833"
     CDS             2735..3574
                     /locus_tag="LP345_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1760612.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3770..4744
                     /gene="sgrA"
                     /locus_tag="LP345_001834"
     CDS             3770..4744
                     /gene="sgrA"
                     /locus_tag="LP345_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBL1760613.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5042..5398
                     /locus_tag="LP345_001835"
     CDS             5042..5398
                     /locus_tag="LP345_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760614.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5401..6558
                     /locus_tag="LP345_001836"
     CDS             5401..6558
                     /locus_tag="LP345_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760615.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6584..7024)
                     /locus_tag="LP345_001837"
     CDS             complement(6584..7024)
                     /locus_tag="LP345_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL1760616.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7184..7690
                     /locus_tag="LP345_001838"
     CDS             7184..7690
                     /locus_tag="LP345_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1760617.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7858..9771
                     /locus_tag="LP345_001839"
     CDS             7858..9771
                     /locus_tag="LP345_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL1760618.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9776..10777
                     /locus_tag="LP345_001840"
     CDS             9776..10777
                     /locus_tag="LP345_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1760619.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10979..11185)
                     /locus_tag="LP345_001841"
     CDS             complement(10979..11185)
                     /locus_tag="LP345_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBL1760620.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11831..12679)
                     /locus_tag="LP345_001842"
     CDS             complement(11831..12679)
                     /locus_tag="LP345_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1760621.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12678..13745
                     /gene="gnd"
                     /locus_tag="LP345_001843"
     CDS             12678..13745
                     /gene="gnd"
                     /locus_tag="LP345_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBL1760622.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGEHEIVEKGE"
     gene            13747..14748
                     /locus_tag="LP345_001844"
     CDS             13747..14748
                     /locus_tag="LP345_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBL1760623.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14745..15029
                     /locus_tag="LP345_001845"
     CDS             14745..15029
                     /locus_tag="LP345_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBL1760624.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15062..15859
                     /locus_tag="LP345_001846"
     CDS             15062..15859
                     /locus_tag="LP345_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1760625.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15873..16706
                     /locus_tag="LP345_001847"
     CDS             15873..16706
                     /locus_tag="LP345_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1760626.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16724..17581
                     /locus_tag="LP345_001848"
     CDS             16724..17581
                     /locus_tag="LP345_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1760627.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17603..18112
                     /locus_tag="LP345_001849"
     CDS             17603..18112
                     /locus_tag="LP345_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1760628.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18149..18550
                     /locus_tag="LP345_001850"
     CDS             18149..18550
                     /locus_tag="LP345_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760629.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18662..19015
                     /locus_tag="LP345_001851"
     CDS             18662..19015
                     /locus_tag="LP345_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760630.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19049..19492
                     /locus_tag="LP345_001852"
     CDS             19049..19492
                     /locus_tag="LP345_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL1760631.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19509..20594
                     /gene="uxuA"
                     /locus_tag="LP345_001853"
     CDS             19509..20594
                     /gene="uxuA"
                     /locus_tag="LP345_001853"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL1760632.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20587..21300
                     /locus_tag="LP345_001854"
     CDS             20587..21300
                     /locus_tag="LP345_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1760633.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7399 a         3301 c         4489 g         6311 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattactt atttctcatt taaacgatgt
     1201 attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt gaataaattt
     1261 cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct agtataacag
     1321 aataagagga acaagtccag aagggatatt tttagtcttt tttaaaataa cttttcagtc
     1381 gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa atagggaagc
     1441 atgaaagaat ctacttaatg gcgcattgat tcatgtgata gaaataaaaa acttttttaa
     1501 attatatcct catgattgta acaaatccag tgatttgttt tggtacaaat aaaaaaaggc
     1561 cccgatgaag ttgtggcaaa agtggtttgc ctcaaaaata agaaggaatt tccaaaaatc
     1621 acttctcaaa ttttgccaca tccccaattg ggtcaaattt gtttatttga atatattttt
     1681 tacataagga tctttaatag ttacattgtc ttttttcatc actttacgga ttgttttatc
     1741 catgaattcc gtatcaagag tttttgcttc ggtagcaatt ttttctagct cagatttgta
     1801 tttgtcttta ttagaacctt tatcctgttt ttttaccatt tttactagat aatagctttg
     1861 ctgataagtc gttggatctg ttacaggaat gatatcagaa acttccccgt tttttagttt
     1921 aaatgctgct ttttttactt cagtaggaat ctctggattg gttgaatcaa aattcatttt
     1981 tccatcagtt tcctttaatg ttttattttt tccataagct tgaacaagct tggagaaatt
     2041 ttccccttca tttgcttctt tttttgcttt atctgcttct tctttagtcg aaaatagaat
     2101 gatctgtgta ctaacttctg gatagaattc tttccaagca gtgtctagat ctttatctgt
     2161 taattttaca ttggctttca aaccgtattg gaaagccagc atctgtttaa agagtttctt
     2221 atatgtctct tctgtttggc caactgcttt taattgttcc ttgtagtttg gaccgagttt
     2281 tttgatttgt tcattatatt cttttgttac ttcctttgaa gaaatctctt ttccgtatac
     2341 atcatcaaat gctttgaaga caatcatttt ttttaatagt gtttgattat ttgatttaac
     2401 ttttgggtta tcataaaaat cctgaactgt aagtgttcca cctttaaacg ttgcaatcgt
     2461 ttcattggac ttgctacaac ctgagaatag taaaattgca catgctgaaa ggcacataat
     2521 tagtagttgt tttttcaaaa aatttcccat cctttcctta ttaaaaacag tctaacagaa
     2581 gaattaggga gacagtcttt cattttcgta aggttgctgt agatattctt agttcgtaaa
     2641 aatctattct ctctatgatg gagaacattt acatagtttt cacgagacaa gaaagaaaag
     2701 ggttgttaaa cttaatataa aggagggatg aaagatgatc aggattattc ggttgattgg
     2761 atctgtttta atagtcttag ttggttttgt tttaggaatt cttgtcaata atgcacttgc
     2821 ggatatgttt attggaaata gtgaatggat tggagcaatt gccggtacgg tcggacattt
     2881 agctgttttt ttactagctt tatttcttgc tagtaaggtc gaaggaaaaa gaatagaaga
     2941 ttatggtgtt tctgttcgag gaaaagactg ggggtattta gcgggaggtc tcgttgttgg
     3001 aattggagtg tttctgctta ttactagtcc attatatttg acgggggcgt atcggttaga
     3061 ttcaggaaac gcaaacattg tgccgctgat aacgagtttt attttattta ttgcagtggg
     3121 ggcatcagaa gagcttttat tccgtggctt ttttcagcat cagatgctta gatttggtcc
     3181 gttaatagca atgattggat ctgctgcatt atttgctctt ttgcacggat tgaatcctaa
     3241 catgacattt ctggcagttt tcaatatctt tttagcaggt tgctttttca gcgcacttat
     3301 ctacagtaca ggaagtttat ttacggctat tggtgctcat attacttgga attggacaca
     3361 aggagctatt ttgggtatac cagtcagcgg aacgcaagaa caaggttttt tctccactct
     3421 gatccaatcg caaaatacaa taattactgg gggaaacttt ggggctgaag catctatatc
     3481 aactacatta ttcttgttag tcttgattgt tggtttgtta ctctatgcat ataaaacaaa
     3541 gcggatgaag aaatacactg ctgtttatca ataaaagatg aagaaagcaa ggctgatatc
     3601 ggtcttgctt ttttaagtct gtcattgatt aaacgaaaaa gtaaacaaat tcaagcgaat
     3661 acacgacatc ttttgttaga ttttcacaac tgactgtcgt gttctcatca ttttcatttt
     3721 atataattcc tttatcaaat agaaggtaat tatatggaga gtgatagaaa tgaagaaaac
     3781 agcgaccgta ttatttgtta ttcttgggct gagtataatt gcagcaatga ttggaatcag
     3841 tacttctgca aatgaacggg caaatgagaa tctttcattt actgtgaaaa ctgatcggat
     3901 tgtttatgac atgacacaac aagtcattac tattccagtc aaaccaaaca aaagcgtgaa
     3961 tgctagtgat gtacatgctg ttctaacata tggttgggat ggtaatggaa gttcagaaaa
     4021 agttattggg gaagtttatt taaaagacgt acaatggacc gctggtattg agtatacaat
     4081 aatgatttct gcagaactat cgattgatga gatcaagagt aaagataaag ttgatttgat
     4141 tgttttttat gatggacaga tgacgatcac ggagaatttg aaaccaagca gttggacagt
     4201 tgttggaccg ccaagcagta cggatagcac aagtagtgaa agcagtacag aaaacacgag
     4261 cggtgaaagc agtacagaga gtacgagcag tgaaagtagc acagaaaaca cgagcagcga
     4321 aagcagtacg gagagtacga gtagtgaaag tagcacagga agcacgagca gcgaaagcag
     4381 tacggagagt acgagtagtg aaagtagcac aggaagcatg agtagtgaga gtagcacagg
     4441 aagcacgagc agcgaaagca gcacaggaaa agtaaataat gaacttgatt tggtacctat
     4501 cataccaact aaggaacaaa agagaaatgc agggagcaac ctaaaaagtg tgctaaaaca
     4561 gcctgatttt gtttctcgtg gaattgatca tcaagaaaaa gcgaaagaaa cagataatag
     4621 aaaaagcgat ttaccagaaa ctggtagtag aaccttgaac aagctaatta catggatggg
     4681 tgtgttactc attttgattg taggagcaag ctattttcgt tctctcttcc atcgagtgaa
     4741 ataaagaata aaagcaacag atctaaaatt gaataaaacg atagattttt gagtgaatat
     4801 ttcattcgag agtgctgtat tgcctggcga agttgtagct ttgccagatc tatttttgtt
     4861 tactaacata tttgagaaac aggaaataac aggaacacaa atggaaaata agagcaagaa
     4921 taattgacaa tgcacactgc gcatggtagt atctctgaaa aatcagtaac gaatctattt
     4981 gtacgttatt catgtagctg tcggaataag tctaaataat agataaaaag gagtatgtac
     5041 tttgtttgaa gaatttattg atatcaatga aaggcaagta tatcaatttt tgaactattg
     5101 ttatgaaaga gacgagaaat tatatgtggt gaaggatatc gctttagatc taaactacac
     5161 cctggctaag atgaattcgg tgattcaaca agcagaatcg ttttgcgaaa ggtatccaga
     5221 atataaatta tcttttcttt cagaaaacaa gatgataaaa gtcgagtttt cttctcagtt
     5281 tttactgagt aaagtttatt ctatactttt agagggaacg attggttata ttttactgga
     5341 ttcactttac aaaggtactt atcaatcctt agaaaatctt agtcaaaaaa ttatataagt
     5401 ttgcgtacga ttcaaagaaa attaagagaa cttaatacta ttttgaaaaa ctatcattta
     5461 tcttgcagct tgaaaaaagg taatccgata gaaggagaag aataccgtat ccgatacttt
     5521 tttcacttga tgtattggca gtcattcgac gaaaatcatt ctgatatatt atcaagtata
     5581 aaaaataaac gtcaactatt agaaaaattt gcgaaacatg cgccatatac gcgtagtata
     5641 gatagaaaga aatggatcag cctactaaga atttcgttgc aacgaatgaa acaaggccac
     5701 tcgattacgt atgtcccaga agagatgaac aaatttgtgc atccattgat aacaaaagaa
     5761 gagtttacgc attacatact agagcctttt tttgaagcaa acttctggtc gatgaatcac
     5821 atcactccaa cagagcaagc ttacctttat tttatgtttg gtgtaatgaa cacctatttg
     5881 gaagaagatt tgttggatac tccagataaa gtacaagaaa gttggggctg gattgaatcg
     5941 tctattgtag aaaattttga aaaaaacttc aagatttgtt ttacaacttc agaaaaaaat
     6001 tatctatatg tcaatttggc aatgatccat ttgtattcaa gggtttttgg gacaaaaaag
     6061 aaggtggatg cttttggaaa atcagcagaa gacagagatt ttcagcatat atttccagtg
     6121 atgtatccaa tcatgcaaca gttttttagt ggggtagctc gcagaattcc agagcttaat
     6181 acttattatg aaaagaacag acggttgatt tttcaatact gtatgttagt cagggatatt
     6241 tttataaaac acgaacaacc tgtcatattc tatattcaat caaagtatgg taaaacacag
     6301 gaattatggg caaagaaaag gatattatct atgactgaac gcccaataaa atatagtgca
     6361 tccgctgatc agttacctga tattgtcatt agcgattatc ctatcgacaa aaaggcatat
     6421 gatcaaacga atacacagat attttactgg aatggacaac ctacaaaaaa tgattgggcg
     6481 cgtctgaaag ctgaaatcat aaaaatcagg aatgagaaaa atagatccat attggaaaaa
     6541 ttggatttcg ttaattaaga aaagcagatt gtttatgcca aaattaagac attgcaaaaa
     6601 gattattttc tttaaaatcg acaagatgac cagaaagcaa gagttcgttg agctcttgct
     6661 ttcttttagt tttagaaagg aacatcctga ttttatcttc gctaaatcca gtcaaaagtt
     6721 ttgcagattg gtcgtagata atcggttttt tcaataaaga aggggatgta cgaatctcaa
     6781 tatatagttc actcaaactg agttcatcta ttctgtgaac aagattttta taactaatag
     6841 aatgagtaga gagcatttcg gtcacgccgt tgtttgtcaa ttttagtaag tggataaatt
     6901 catttttggt tagtggttga cgaattaagt tctgttcgat aaacggtata tcatggacga
     6961 taagccaacg ttttgcgcgt cttgaagacg agcagccaga acctgtatac aatttaatca
     7021 tcatacattc ctccaatagc taagtattta tgaaataata acatgaagaa atagtcgaaa
     7081 agtgccattt agaggtgtaa aataagaaaa tgttgtcacg tataatggaa ctagctagat
     7141 aagaaatact attaaatcaa gaaaaaagaa agaaggcaca agtatgtcaa acacagccga
     7201 cgcaatagta gtgatcgatt tacaaaaagg ggtatgtttt gattcttcgc cgatacacga
     7261 attagaaaca gtgacagcat tagtgaataa aagaatcaaa acatacgaaa cgattgggaa
     7321 accagttatt ttcgttcaac acgaagatgc tcaattagtg ccacaaacaa aaccatggga
     7381 gctattgtcg gaattatcta ttcctgagca cagttatttt gtgagaaaaa cccatgcgaa
     7441 ttcattttat aagactaatt tgagtgtttt attaactgaa ttggactgtc attcgatcga
     7501 attatgtggg gcacaagcag agtattgtat agatacgact gtgaagtttg ctcatggatt
     7561 aggataccag cttatgatgt gtagaggagc aacgacaact tatgataatc cttttatgaa
     7621 agcaaaggaa acaatcgctt tttacgagaa aatttgggat aaacgatttc tgacattttt
     7681 ggagcaataa gttgtttctt cgtttaaaaa aagcagaatg gatactggtt tatccattct
     7741 gctttattac gtaaaatgag aaaataatcc tgttctattt ttatgggata aaccatttat
     7801 tttttgtata aaaaatgttt gcgtttacat ataattctcc tagaaacata aaaaggagtg
     7861 aatagcttga gaacaaaaca agtattaaag ggagcgttgg tcatcttatt tgctgtaagt
     7921 acaagcgtcc cgcaatggac agtatatgga gagagcattt cttccgaatc ggaatctcgg
     7981 gaggtagaaa ccacagaaac tactgatgct ggaaatgaaa cgaaatcgag tacttcacaa
     8041 acagaaacaa atactgaaac aacggttgag acatctgtta ctagcacaga tcaagaaacg
     8101 accgctacca cagataacca acaaacagaa gaagcaacag ctacaaaaat gtcaaacgac
     8161 gaatcctctt ctgctaaagt aagtgacaaa gagaatggga cagaaaatga tgatatcggt
     8221 aaaggtgaaa atttcaatgg taaagaatat ttgaattact tcggtaaaca gatgacagaa
     8281 atacttaatg gaccaacaga agacatcaag tcaaaattaa tagagttatt agtcactgag
     8341 cttgctgtta atgattatgg tgtagataaa gagattatca aacatctgat tgctacttat
     8401 ctattgtacg atatcgcttt tgcaaaaaac agtgtgttga tgtcgatgct tggaggtaca
     8461 gatgatggga caacgcctac agaaaacaca ggcttctatc caaatacaaa acaacttcat
     8521 caaactgtac taaacaaaca agatggcaaa atgatggatg tatatgcata ttatgtcgat
     8581 caaggttcag ataaaacagt catgatccat ggcggatttc gagggaattg gaataacggg
     8641 atcgttacag aagaatacaa tgatttttat aaggccgggt ataatttatt atttgttgat
     8701 tccagagcga ctggtaatag cggaggcgat tatgtgacct atggacaata tgagtcagat
     8761 gacgtccttt actggataaa tcaagaagtt cgagagcggc catctcaaaa gattttactt
     8821 tatggtggtt cgatgggagc agctacgatg atgtctgtat tagcgaaaga tattcctgtc
     8881 aatgtcaaag gaattattga aaattgcgga tttgcatcaa ttgatgaaca actacgtttt
     8941 acgtacagcc agacagtagc ccccgcacta ccggatgcca taaaaaatca gttagacatc
     9001 attggggatc aagagcatga agatttattt atgggccttt tgaaacaata ctattttgat
     9061 caggagatgc atttggatac aaaagctgct ctacctacga ttggaatgtc agattcattg
     9121 cctaaattga ttatccatgg aacagcagat gatgtagtac ctgtgtctaa cgcgcaaaaa
     9181 ttatatgagt tatcaggagg gtataaagat cttttattag tagaaggagc agggcatgga
     9241 aaggcacagg aagttgacca tgctgcctac acgaaacatg taacggactt tttgaaagta
     9301 gtgttccatg atcagataaa cgtaaagtat gtggatgaaa acaataaaag tctactcaaa
     9361 gaccaggacg aaatccagct ttacggagct tatggagaaa attatatgac agagcaaaag
     9421 acattcgaag gatacgaatt agcaaatgtt gaaggaccga ctgaagggat ttttaatgag
     9481 acgataccaa ctattatttt ctattacaaa aaaatcccag tagctccacc aaaaaagcaa
     9541 gatccgacag agaatgcaga caataaggga aagaatgaac ctcgagagga tcaatcaagt
     9601 gatgatacgc aaccgattca gatgacagtg aaagtacaaa aaaagacaga tgcaaaaaaa
     9661 agaatgttgc cgaaaactgg agaaaagaaa cattcgcttc tcatttattc aggtggattt
     9721 ttatctgtta gcacgattat cacatggatt tggcgaagaa agagagggta aatgaatgaa
     9781 atggttcaag cgaatagtga ttgcagtacc agttatcatc gtagttattt tagtcactgt
     9841 atttttgatt aatcaaatca caccaaagcc gattagcttg cttgttagaa aacaatttga
     9901 cacaagtgaa aaagaacaag tatatgcccg accagatgat ttccagcaaa aaatcgaaca
     9961 aatcgatata aaaaaagaaa tatcctatcc ttcaaagtac aaaaataata atatggatat
    10021 ctacacaccg aaagtggaaa agaaaaaatt accgattctt ttctggatgc atggaggcgc
    10081 atatgtagga ggggataaaa atgattgtcg tgattatttg gaatatctat gttcagacac
    10141 gcagcaaatc atcgtaaata tagattatga acgatcaccg gaagcaaaac atcctacacc
    10201 agttatccaa ttgaacgaag ccattcaagc agctaaaaaa gagataaaag atcaagcaga
    10261 ttggtcgaat atttcgattg gtggaaattc ggcaggtgca caaattagtg gagaatattt
    10321 gttagcactt caaaatgaag aaattaaaaa agctgatcat cttgatccga ctttggagaa
    10381 caagcagatt acgaagttta tttctttgtc tggtctgttg gatccttctg cacttactca
    10441 agtaagtgat aaaatctcta gctttcttta tgaaaaatgt ggatgggctt actttgataa
    10501 taaggacttt gaacaatcag agaaggtcaa aagtttagcc ttggtcagac atgcggatcg
    10561 ttggacgcaa aacacattct taacggatgg aaatacaaat acgtttacga aacaaatgga
    10621 agaagtaact tctgtatttg agaaagcggg ggtgaaagtc acaaaagtag attatgcgga
    10681 gaaaaatgct gttttgaacc atgaatatca gtttgatttc agcaataaac aagcgcaaga
    10741 aacatatcaa aagttagtaa tgtttttcaa ggagtaaagt cttatgatgc aaaagaggtt
    10801 gtaatctgtc acttagctcc aagtcacaag gagcaatttc aataaacaag cttttcatgg
    10861 tttatgaata ttgtaacttg tgactgagga gttagagatg gcaaggggca ccttttattc
    10921 gaaatttggg aatatcacac gattattgtc acgatctctt ttacgtaaat tttataagtc
    10981 agatttgttg ttttgatcgt ttaaaaaaag caacaaatcc gaagcctgcg gaggcaagaa
    11041 gggacaaaaa gccgagtggt aagcaaaaga atgctggttc cactaatatt ccgttgttat
    11101 tgatataagg ctgggaacaa agatgaatag caaataaaat caatgcacta gcgaaaaaaa
    11161 gcaaagaaat atggatagct ttcataagca gcacctcctt ttttataatt gtatgataaa
    11221 tagattaaga atctataaat gtgacaagtt tgttaggatg tgaataaaat gatcatctag
    11281 cgaacttgaa acaaagatgg ctaatgataa gcaattaatg attcagcaat cagataggta
    11341 caaagtttac catcatacgt ctagaccaat aatagaaaat atgggaatat aatagaaaag
    11401 atttaggata cccccaaaag aatttcccca aaaattcgat gtatcctaaa cttttttatt
    11461 ttacataaca atcatatcaa ctgtgaaata aaattacaaa tgataaccta aaatgaggcc
    11521 aaaagccagt gttatcaagg aaatacttaa ttcaccaaaa ttttttttaa ttttttagaa
    11581 aataagaaac aaaaataata aaaaaaagaa aagataaatt ttttactact gtatactaac
    11641 tttgttatcg catctaacaa gtaactcgaa taataccaat acaaccttct ccaaagatgc
    11701 gatgacatac gttctaaccc accgactatt gatgttctgt accacccttg cagaaccaaa
    11761 aaagccacta ccaaatattt ggtagtggct ttttttgttt tatggatttt tcgctttttc
    11821 tgttatggtg ctattctttg atttcagaaa tagtatgtcg aactttagcg atagaacgac
    11881 gtgattcttt ttcgttgtaa aacatcaaaa tcacatatag agagtccaaa atgcttagtt
    11941 gagaaatacg ggaagctaaa gcttcagatc ggaattctgt ttcttcagaa atagaaataa
    12001 aaacgacatc gccaagttta gcaagggaag aattagcttg gctagtaata acgattgttt
    12061 ttgctccagt ttttcttacg gtttcagcaa tatggattgt ttcttttgat tgccctgtgt
    12121 gagaaatcaa aacagcacag tctttttccg tcaataaaga agcttccatc aattgaatat
    12181 ggtaatccgt gctgtgagaa gttgcgatag gggaacgcaa aaatttatga taagcgtcag
    12241 ttgctacaat ctctgaaccg ccaacaccga aaaaatagac acgtttagat tcattgataa
    12301 tagtagccgc tttttttaga tccttttgtt gtaacaactt ttttgtgtca tttaaagttg
    12361 aaatactaga ctcgaacacc ttttgcgcca tagtgagctc agtatctgtt ttctgaatat
    12421 tttcgtggat agaaatagca gatagatcat tttcttggat caacatggcc attttaaaat
    12481 ctttaaatcc attataacca agtttttttg taaattgaaa aaaagtagag tcagcaatgc
    12541 ccagttcact tgctaaattg ctaataggac tatgacttac tttgcttgga ttttctaaaa
    12601 tataatcggc gatagcctgt tcttttgggc tgaagtcgtt gtacattgtt ttgatttgta
    12661 gtcttatgga gacgctcatg agaattcctc attttcataa taagattatc attttttccg
    12721 ttctcattaa tgttaaagat acaaggagag taggaaaaaa tcaaacaaaa aatatttttg
    12781 taaaatctat ttacaaaaaa atttttttgt ataatgaggg tataagaaat ggaggcgcta
    12841 tcatggaaat tggtgtaatt ggtttgggaa aaatgggatt gaatttagct ttaaacttaa
    12901 aagagcacca tcacaaagta caaggactcg acatttcaag tacagctgtt agtcaggcaa
    12961 gagaaaatga cattcctgct tatcaagaga tctctgaatt tctagctact tttgagcaga
    13021 aaaaaatcat ctggttaatg cttcctgctg gagagataac cgaaaacatg ttaagaaaac
    13081 tttttccaaa actcggacca ggagacatta ttattgaagg cggaaactct tattataaag
    13141 attcaatccg tcgagcagaa gagtttcaga aaaatgaaat cggttacttg gattgtggga
    13201 cttctggagg aatcgaagga gcacgacatc aagcctgctt aatgattgga ggagataaag
    13261 aaacttttct atccgtggaa caattattca aagatgtagc aattgaaaga ggatatctgt
    13321 atgctggtgc atccggaagc ggacacttct tgaaaatgat ccataatgga atcgaatatg
    13381 gaatgatgca agcaatcggt gaaggattcc aacttgtaca aaaaagtgag tatgcttttg
    13441 acttggaaca agtcgcacgt gtttggaatc atggttcggt gattcgcggc tggctgatgg
    13501 aaatcatgga agatcagtta aacgaacatc ccaatttaag taattatcgg ggaatcgttt
    13561 ctgcatcagg tgaagcaaaa tggacggttg aaacagcgct agaaatggct gttccagttc
    13621 cagtaattgc aactagtttg ttcatgagga atctttcaca ggaagaagat agtttttcag
    13681 caaaagtagt ttcagcacta agaaatgggt ttggcgaaca tgaaatagtt gaaaagggtg
    13741 agtaaaatgc cagattatca tatagcaatc gttaattcca gcagtttcgg aagagtcttt
    13801 ccacaccact tggaaagatt aaagtcagtt ggagacgttc atttctttac tgttgatcaa
    13861 gagattccag gaaaagaact agcggagtta cttaaaggat tcaatatcat tattgcaagt
    13921 gttacgccat tttttcgacg agattttttt gaaaacaaag atgaactgct attgatttcc
    13981 cgacatggta ttggttacaa caatattgat ttaaaagcag caaaagaaca ccagacaatc
    14041 gtatctatca tacctgcttt agttgaacga aatgctgtag cagaaaataa tataactaat
    14101 ttgttgtcca tgcttcgacg cacgacacaa gcacaagcaa gagtcaagga cgatcgatgg
    14161 gaagatcggg cggagttcgt cggtaggacg ctgtttaaca aaacagttgg tgtgattggt
    14221 gcaggaaata ccggaagcgg agtaatcgaa attttgcgta acggttttcg ctgtgatgtt
    14281 ctagcttatg atccttacaa atcagattta tacatcgaaa gctttggtgc aaaaaaagta
    14341 gaacttcaag aattactgga acaatcagat atcatttgtt tatgtgcgaa tttgacagaa
    14401 gagaactatc acatgatttc tgataaagaa gtcgatcaga tgaaagaaaa tgtttatcta
    14461 tctaatagtg caagaggcgc tctagttgat gaagaagcga tgattaatgg tctgaaaagc
    14521 ggaaagatcg caggatatgc cacagatgtt ttagaagaag aaccgggacg tcaagatcat
    14581 ccgtatttag cgtttgaaca agtagtgatt acgccacata tatcggccta cacaagggaa
    14641 tgtttagaag caatgggtga aaaatgtgtc agagatgtcg aacagatcag tcagcacctt
    14701 cttcctgaac gttctgtcca gacaaagagc aactatataa aaggatgatg aagaaaatgg
    14761 tgaacggttt aaaagtgaaa acaggccctc aattttattt atatgaagaa ggtggtattt
    14821 caaaagtttc tgatctcttg aaatcatacg gcgcgaaaag agtactggtc acccacggaa
    14881 cggtatcatg ggaaaaggcg ctacctaaat tagtattttt gaatgacgaa acgattcaat
    14941 ttttttatca tcgttattct ggagaatgta gttatgctga agccagacga atagctacaa
    15001 tcatcaaaaa aatgaaatcg atttcgtagt tggcgttggc ggaggaaaac tgaccgatct
    15061 agtgggttat agtgccaatc ttgcaagaat cgatttcgga gtcatcccta ctttagctag
    15121 taattgtgct ccatggacac ctcttgctgt catgtataag gagaatggac aagcagaagg
    15181 gaaaacagaa cacttttaca gacaagctgc tttttttata acagatcccc aattagtgat
    15241 tgattcccct gttccatatt tcattgccgg gttagcagat acactagcaa aatggtatga
    15301 atctgagctc atcttagaac aagatttttt gcaagatgaa tcatttttga agctagcaca
    15361 agatactgcg aagatctgca aagaagagat tttgaatcat tctgctaaag caatccaaga
    15421 tatggcacaa agaaaactga catcggagtt caaacagctt tcagagatta tctttgctgt
    15481 tgctggttta gttggaggat taggagataa atacgcaaga aatgtggcag cacatgctat
    15541 gcatgacgct atcagtaaat atattccgga aagccatcgt tttctacatg gagaaaaagt
    15601 agcgtatggg attttctatc aactggcact agaaggtcgc tgggaaaaaa tagacgagtt
    15661 atatcctttg tatcgggaat tagaactgcc ggtttctcta gaacaaatgg gattatttcc
    15721 gaaagataaa cagataatag ataaaatggc tgaatttatt gattcgaaag agaaagtgca
    15781 tttgattcct atagaggtaa cacagaaatc actgatacag tcaatgatgg aactggaagg
    15841 ttatatcaga aagatctgaa ggaggaggac acatggaaac attaagtgta gtacaaagtt
    15901 tgttgattgc tttatgggta gccgcggtta tgtcccgctg gttaggtgga ggagccacgt
    15961 tgaccttacg tttttctcct ttgatgactg gattagtcgt cgggttgatc atgggggaag
    16021 ttgcacaagc gatgattgtt acagccgctt tgcaaatgat ttatatgggg gttttttctc
    16081 caggaggatc aatgccagct gaaccatcta ttgcagcagc tatcgcagta ccagtcgcat
    16141 tattagggga tctgtcgcca gaagcagcga ttgccgttgc ggtgccagtc ggattgctcg
    16201 gaagttactt gtatcagttt cgttttttca tcaatacttt tttaggtaaa tatacagaca
    16261 aagctgtaga agatttgaat acaaaagcta tggcccgatc aattattctt tatccaacgg
    16321 ttgcctcatt tttattattc gttccgcttg ttttcattgc tttatattta ggggcgccat
    16381 tgatcgctga tgtaatcaaa gctttagagg gaacagtcgt tatccacatt cttgaagtag
    16441 taggtggagg gttagcggca atcggtatcg cgacaactgt atacgttatc ggtcgaaaag
    16501 attatctggt ctttttcttc cttgcttatt ttatgagtgt tgttttgaaa tctttagata
    16561 ttacgatggt tacttatgcc atttttggga ttattatcgc tttgatcttt gtccagtcgc
    16621 aaaaagggaa acaagtacag cctgccacaa gcaataacaa ttcagcatct tttgatgacg
    16681 aagatgacta tgatgacgga ttttaattta ggaggaatgg gaaatggctg aaataatgga
    16741 taatcaaaca ggtgctcctg aagaaatcac gaaaaaagat gtaacaaaag cctatctgag
    16801 atggcatttt gcaaacgaaa ttcctcactc ttttgaacgt tacttggcgc catcactact
    16861 atacggaatg atgccaatct tgaaaaaact ttataaagat gaagactctt taaaagcagc
    16921 atataaacgg cagttactgt tcttcaacac tcaattaagc tggggtggcg gtgtgattac
    16981 tggcctaatg tcttctatgg aacagcaaag agcagaagaa gagtatgaag aaaaagagat
    17041 cttgatgcag gatgacttga tgtataacac gaaagcggga ttgatggggg cactagcagg
    17101 aatcggagat gcaatcgatt caggaaccgt ccaatatatt tttatcgcaa tcgcggtacc
    17161 ttgggcacaa cagggaagtc ctttaggcgc actttttcct tttatctgct ttgggttgta
    17221 tcaggtttta ctaggggtat ttttcgcaag acaagctttc actatgggcc gtaatgctac
    17281 aggcctaaag caaaacactg gtgttcagac agcgattgaa atgctatcag ttttagggtt
    17341 gtttatgatg ggggtgcttg cgggaaacta tgtaaaagta gaatcttcat tgaaatttgc
    17401 gatatccgga cgtgagtttg ttatccagga aattcttgat caaatcgtgc cagggatatt
    17461 acctttagct gtcgtaatgg gtgtgtactt gttctatacg aaaaaaggat tgaaagtcac
    17521 acaagcatta ttatggctga ctggaatatt aattgtgcta gcaggaatcg gtattttata
    17581 aaaagaaggg aacgtgaata agatgggtgt agtcaattta gcgcgtgtgg atgagcgttt
    17641 gatccatggg caagtaatgg taacgttatc tcaaaaaagt ggagtgaatt ccatttttgt
    17701 tgtagacgaa gttgtagcaa aagataaatt tatgagagat ctttacaaaa atgcaggaag
    17761 ccgtacagga caaaaaacaa ttgtcattac accagagaaa gctaaattct attgggatga
    17821 atatcaattt aaagaataca attgtatttt gatcgcaaaa acagtccaaa cgatttacga
    17881 cttagtaaaa cacggaatcc ccatggaaga attgaatatt ggagggattg ctcaaaaaaa
    17941 tcctgataca gatcttttag tgacgaaatc tgtttattta aataaatcag atgctgaaaa
    18001 attgaaagaa atgaatgaac aatatggcgt aaagaatatt tattttcaag ccactccatc
    18061 tgcacctaaa acaggattaa aagatgtatt gaacaagttt gatttgtcat aaacaaatgc
    18121 ttagaaaaaa gataaagagg gcgaaaaaat gaagaagaac gagctgtttc gtgattggga
    18181 atttcgttat cgctatattt accgtaagcg ccgtacaaaa aagagtaaac agcgttttct
    18241 ttcagcatta gtatcagata tttacagtat gagaacagat gtgacagtca ttgcttacga
    18301 tacgctagcc taccgatcaa aaaatattta tgttggagat atcgaaaaag cagagaaagt
    18361 tatctgtact tattacgata cacccgttca tgcattagga agttatttca tgtttgattg
    18421 gaaagaccaa aggaaaaaaa caatctactc tatattattg tccttcattt tgttgttcag
    18481 tttaggttgg tggggaatga tgatatataa caaaaatcct catcacgtat tcgatctgct
    18541 atccgtataa acaggtatca ctgtactagc atttgggagc tactttttct tattgggaaa
    18601 agcagctcgc ggatggccta gcagacaaac ttttattcga aatacttcat ccatattaac
    18661 gatgctagaa atgatccgta cgattgatga tccgagtgta gcgtatgcgt ttgttgatga
    18721 aggctgttat ggagaaaagg gcttagacag cgtgagatcg ggtatgaaaa aagaggctat
    18781 tcttttttat ctagactctg ttggggcaga tacaccgcta cagttttcgg gaaattattt
    18841 ttcaaataaa gaacagtggc tgaaacaagt tgataagttg aaagaaaaaa acgtcaatta
    18901 tatttttagt gcaagaaaaa agcaagcgca gttcttctat ttgaccaaaa cagatttacg
    18961 agggaaaaca tttaattggc aaaatgccaa tcagattatt gctctttttc gataagtaaa
    19021 aagtgcaaaa caaggagtga gaagactaat gttggaaatc atgatcgtta cacatggtaa
    19081 gttgagcgaa ggactgaaag atgcggcgga agtaattgtc gggacatcga gccatattga
    19141 aacaatgtgc ttagagtctg gggaggacat ccaaacattc ggagagaagg tcaaagaaaa
    19201 attaactatg atcaacacag cagaacccat gctagtattt gttgatctaa ttagcgcaag
    19261 tccgtacaat caagcgctct tggcagtcaa tgaactgact gaagaaaaga aagcagccac
    19321 ttatgtcata gggggcgtga atctgccaat gttgttagaa gcaatcaatc atcagatgct
    19381 tcacacaccg atagaagaag cggtggaaca aattgtcaaa caaggaaaag ataatttaac
    19441 tgtttggcat gcttcagcgg aagaaaaaaa attagatgag gacgattttt agaaggaagg
    19501 ctgaaaagat gaagtgggga tttagatggt atggtgaaaa aggggattcg atcccattaa
    19561 aatatgttcg ccaaataccg ggaataaatg ggataattgg aactttgctg actaaaatgc
    19621 ctggagatgt ttgggagatt tcagaaattg aggagttgaa agcatctgtt gagagccaag
    19681 gactggaact gcttggaatt gaaagtgtag cgatccacga tgcaatcaag gcagggacag
    19741 atgaacgaga ttactatatt gataactata tacgaacaat caaaaacttg tctcgatgtg
    19801 gggttcgatt gatttgttat agcttcaaac caatttttgg atgggcgaaa actgatttgt
    19861 ttaatgaaaa caacgatgga agctattctc ttttatacga tcagaaaatc gtcgatcaga
    19921 tggagccagg agaaatgtat caattgatac acagccagtc aaagggattc aaattgccgg
    19981 gttgggaaga agaacggttg aaaaaattcg ctcagctgga aaaactgtat gaaggaatga
    20041 ccgaagaaga attatttgaa aatctgactt attttttaga aaaagtgatt ccagtgtgcg
    20101 aaaaagcaga tgtaaaaatg gctatccatc cagatgatcc gccatgggaa ctttttggtt
    20161 ttcctagagt gacgaaaaat cttggcgact tgaagaaaat tctaaatgca gtagattctc
    20221 catataatgg actaacgctg tgcacaggat ctttaggggc aaatccggaa aacgatttag
    20281 ttgaaatcat ccatgaggta ggttcgcgca tccattttgt ccacttcaga aacgtggagt
    20341 ttttaggaga aagaaagttc aaagaaacgg cacatccctc tacagaaggc tcccttgata
    20401 tgtatcatat tatgaaagcg ttggtgcaag aagggttcga cggtcctata cgccctgatc
    20461 atggtagaac cgtgtggggt gaagtggcta tgcctggata tggcctgtat gatcgtgcaa
    20521 tgggactcac ttacatgcaa ggtctatatg aggcgataag taaggaaaaa ccactgggag
    20581 agcattatga ataaaatcaa gctcttcatc tttgatatgg atggcctttt attagaaact
    20641 ggacgtttag cttatcgtgc ttatgtaaaa tcagcacaaa agtatgatta tgaaatgcgt
    20701 aaggaagtct attatttact aactggccaa acagaaatgg cgataagaga acaaatgggc
    20761 attttgtacg gagaagatgt tccatatatc aaatggcgag aagcaatcaa tcaatataaa
    20821 gaaaaaatcg tgaaagaaga taagagagta tatacgaaaa aaggagcaga agaaatttta
    20881 tcttttgcaa aagaaagagg aatccataca atcgtggctt cgtctaatac acgggtaaaa
    20941 gtagaaatgt atttaaaaat ggaaaatcta tatgccttgt ttgatcaaat catttcaggg
    21001 gatgatgtaa aaaaaggaaa gccggaacca gagatctttt tgaaagcttg ttcaaaaatg
    21061 aatattcctc caagtgaagc acttgtattt gaagactcga ttgcagggat cgaagcagca
    21121 aggcgagcgg gcattttgtc ttttctcatc aaagatcatt tgatagggtt gcccgatcat
    21181 aatgggaagc ataagttgaa agtagatgta agtttatatg aatccaataa agcagactat
    21241 gaattttatg acctgcatca agcaaaacga tttttagaaa gtaaagggtt gtatctctaa
    21301 taaagaggac tattttctag tcctctttat ttattgtcct gcacgactga gggaacagat
    21361 gaaaaagaag taatttttta ttttgaagta tctaccttat ttgtagtgaa caatttagaa
    21421 caaacacaaa acgcatctac tgttatctac cagtagatgc gtttaaagag aagaacgaga
    21481 atcgtccata tgagggtttc
//
LOCUS       DAFEIE010000043        20784 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFEIE010000043
VERSION     DAFEIE010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.044"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(20..1576)
                     /gene="rny"
                     /locus_tag="LP345_001855"
     CDS             complement(20..1576)
                     /gene="rny"
                     /locus_tag="LP345_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBL1760634.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(1987..3036)
                     /gene="recA"
                     /locus_tag="LP345_001856"
     CDS             complement(1987..3036)
                     /gene="recA"
                     /locus_tag="LP345_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBL1760635.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(3145..4386)
                     /locus_tag="LP345_001857"
     CDS             complement(3145..4386)
                     /locus_tag="LP345_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBL1760636.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(4626..5204)
                     /gene="pgsA"
                     /locus_tag="LP345_001858"
     CDS             complement(4626..5204)
                     /gene="pgsA"
                     /locus_tag="LP345_001858"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBL1760637.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(5413..6336)
                     /locus_tag="LP345_001859"
     CDS             complement(5413..6336)
                     /locus_tag="LP345_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760638.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(7075..8361)
                     /locus_tag="LP345_001860"
     CDS             complement(7075..8361)
                     /locus_tag="LP345_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL1760639.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(8354..9622)
                     /locus_tag="LP345_001861"
     CDS             complement(8354..9622)
                     /locus_tag="LP345_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL1760640.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            9874..10335
                     /gene="mscL"
                     /locus_tag="LP345_001862"
     CDS             9874..10335
                     /gene="mscL"
                     /locus_tag="LP345_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBL1760641.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(10394..10840)
                     /locus_tag="LP345_001863"
     CDS             complement(10394..10840)
                     /locus_tag="LP345_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1760642.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(10933..11178)
                     /locus_tag="LP345_001864"
     CDS             complement(10933..11178)
                     /locus_tag="LP345_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBL1760643.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(11292..11870)
                     /locus_tag="LP345_001865"
     CDS             complement(11292..11870)
                     /locus_tag="LP345_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1760644.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(11947..12477)
                     /locus_tag="LP345_001866"
     CDS             complement(11947..12477)
                     /locus_tag="LP345_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBL1760645.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(12481..13341)
                     /gene="rlmB"
                     /locus_tag="LP345_001867"
     CDS             complement(12481..13341)
                     /gene="rlmB"
                     /locus_tag="LP345_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBL1760646.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(13334..13729)
                     /locus_tag="LP345_001868"
     CDS             complement(13334..13729)
                     /locus_tag="LP345_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBL1760647.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(13726..15138)
                     /locus_tag="LP345_001869"
     CDS             complement(13726..15138)
                     /locus_tag="LP345_001869"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBL1760648.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(15135..15671)
                     /gene="cysE"
                     /locus_tag="LP345_001870"
     CDS             complement(15135..15671)
                     /gene="cysE"
                     /locus_tag="LP345_001870"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBL1760649.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(15757..15996)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(15993..17453)
                     /locus_tag="LP345_001871"
     CDS             complement(15993..17453)
                     /locus_tag="LP345_001871"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBL1760650.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(17623..18780)
                     /locus_tag="LP345_001872"
     CDS             complement(17623..18780)
                     /locus_tag="LP345_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBL1760651.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(18814..20184)
                     /gene="radA"
                     /locus_tag="LP345_001873"
     CDS             complement(18814..20184)
                     /gene="radA"
                     /locus_tag="LP345_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBL1760652.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(20247..20774)
                     /locus_tag="LP345_001874"
     CDS             complement(20247..20774)
                     /locus_tag="LP345_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBL1760653.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         5473 a         4593 c         3706 g         7012 t
ORIGIN      
        1 tcttcttttg tattttttat tatttagcat aatcagttgc acgagtttcc cgaataacga
       61 ttactttgat gtgtccagga taatccagtt cttcttcgat tcgtttacga atatcacgta
      121 ctaaacgaac agcgtctaaa tccgagattt cttctggctt gaccattacc cgaacttcgc
      181 gtccagcttg aactgcgtaa cttgattcta caccggcgaa gctgttcgaa atattttcca
      241 gacttcttaa acgacggatg tagttttcta atgattcact tcgcgcacca ggtcttgctg
      301 ctgagagcgc atctgctgca gctacaagga cagagataac agaagtagct tccacatctc
      361 catgatgaga agcgatcgcg ttgattacta ctgggttttc tttgtacttg gcagctaatt
      421 ccgcaccgat ctcaacgtga gatccttcaa tctcatggtc aagtgctttc ccaatatcat
      481 ggagcaaccc ggcacgtttt gctaattgga tatcttcgcc aagctctgct gctaagatac
      541 cagctaattt tgcaacctcg accgaatgct tcaagacgtt ttgtccataa ctagttctga
      601 atcgcagacg tccgatgatc ttgattagat ctggatgaag tgtatgagca ccgacttcaa
      661 acgctgcctc ttccccgtat tcgcgaatac gttcatccat ttctttacga gatttctcga
      721 ccatttcttc gatacgcgct ggatggattc gtccatcttg tatcagtttt tccaaggtca
      781 tccgtgcgat ttctcttcgg attggatcga atccggaaag aacaactgct tccggtgtat
      841 catcgatgat taaatcgata ccagtcagcg tctcaagcgt tcgaatatta cgaccttctc
      901 gtccaatgat acgacctttc atttcatcat tcggaagggt aacgactgaa acagtcgttt
      961 ctgaaacttg atctgctgcg cagcgttgaa tcgctaatga taataagttt ttcgctttgc
     1021 gatctgcttc ttctttggca cgctgttcag attcttttac cattagagtt aactcatgat
     1081 tcagctcttc ttcagtcgat ttcatgatga catctcgtgc gtcctctttt gataaaccag
     1141 caattttttc tagttctttt tgttgatctt caatcatttt ttcaacgtct ttttctcgct
     1201 cttcaattaa ttgctgtttt gaactaagtg cttcttcttt actttcaagt gagttctcgc
     1261 gtttttctaa cgagtcatct ttacgattca gcgtttgttc gcgttgaatc aaacgattct
     1321 cttgagattt taattctaac ttactttctc tcagctcact ttcaacttca gaacggtatt
     1381 tctgattttc ttccttagct tctaacaatg cttctttttt tagagtttct gcttcttttt
     1441 ttgcactatc gatgattcca gcagctgatg attgtgcacc agctatttct ttctcgtgac
     1501 gtgactttgc gaccataaac cctaaaccaa gaccgacaat taaaccgatg atagcgagga
     1561 gaatgttgaa taccataaaa tccacctcca tactatcttt ttcattttta tcatctatac
     1621 agcttctatg ataaattatt ctaaactcgt caatatgcat cttcgcatat atgtgtacaa
     1681 aaaacatgca caactttatt ctaatgtttg taccccgtag tgtcaacttt aaataaacaa
     1741 agaaacggct ttctacttat tcattaaacg atggttttta aaataaatga cactagtttc
     1801 atataggtaa acctttaaat tgagaaactt ttctattaaa ttattctttg tagatgaaca
     1861 gatattttta ttttatgtac ccactcgtat aattaaataa ctcacgattt ctttattcaa
     1921 taaaaaaacg gcaggtcaag gagagtacct actcttcaga ccagccgttt ttgtttatca
     1981 taatttttat tcttctacta aaggcaattc ttcttgtcct ttttcatctt ctgggacagc
     2041 gacttcttca ccaataccat aagctgctct aactagagca gaaacttctg ccatcatttc
     2101 aggatgatta gccatataga ttttagcgtt ttcccgtcct tgaccaatcc gatcttcttt
     2161 ataagaatac caagcaccgc ttttatcaac aatgtctttt tctactgcca tgtctagaag
     2221 ttctccttct tgtgagatcc ctaaaccata catgacatct acttcagcga ttttgaaagg
     2281 aggtgctact ttgtttttta cgactttgat ctttgtacgg ttaccaacaa tatctgtacc
     2341 ttgtttcaat tgttctgcac gacgtacttc caaacggatc gttgcgtaga atttcaatgc
     2401 gcgtcctcca ggagtgattt ctggattccc aaacatcacg cctacttttt cacggatttg
     2461 gttgatgaaa atagcgattg tttttgtttt gttgatcgaa ccagagagtt tacgcaatgc
     2521 ttgagacatc aaacgtgctt gtaacccgac atgtgagtca cccatttcgc cgtcgatttc
     2581 tgctcgtgga actaaagcag caactgaatc gactactacg atatctacag ccccacttga
     2641 tactaaagca tcagcgatct ctagaccttg ttctcctgtg tcaggctgtg aaagaagtag
     2701 ttcatcgata ttcacaccta atttttgtgc atattgcgga tctaacgcat gctcagcatc
     2761 aatgaaagcg gccgttccgc catttttttg tacttctgca atagcgtgta gtgcaactgt
     2821 tgttttacct gaactttcag gtccatatac ttcgatgata cgtccacggg ggtaaccgcc
     2881 gacacctaaa gcgacatcta acgcaagaga gccacttgga attgtagaga tttgttggtc
     2941 gattttttcg cccaatttca taatagagcc tttaccatag ctcttttcaa tttttttcag
     3001 tgcagcatct aaggctgctt tacgatcatc tgccaatacg ataatcctcc ttatatttac
     3061 aaatcagagc aacatttcat tatccttatc atatcttttt tagtgaaaaa aagcaagaaa
     3121 aaaccgaaca aatattcgca tttatcattt tcttaaaagc tgttttctca aaagatcaaa
     3181 tccttgcata accgcattat atctgatagc agcacgatct ctggcaaagt gatatttttc
     3241 cgaaaccacg ccgtctttag atgaaatagc gatccatact gttcctgcag attgaccttc
     3301 taacgtgtcc ggtccagcca ctccggtgaa agctacactg taatctgttc ttgctatctc
     3361 acgtgcttga atggccatct gctccacaca ttctttgctg actgttccat attctgctaa
     3421 tagctccgga tcaatctcca gaaaaccagc ttttgtttgg agcgagtagg taacgaatcc
     3481 gcctggaaat acttcagata caccagcaat gtcgcctaat gcggcttgga aggcgccggc
     3541 tgtcaaactt tccgctgctg ttacagtctg cttgttttct ttcagtagtt ccactacgac
     3601 ttttgctagc gaattatcat cgccgtatcc ataaaaatat tcccctactc gttcttggat
     3661 tttttcttct aatgctaaaa gagcttgatt ccctgcctga acatcatttg ttttcactgt
     3721 cagtcgtaat gtcacttcat ttggtttggc atatggtgcg atcgttggat tgatctgtgt
     3781 ctcaatcaga tcttttagct cagtgaccag tcgcgattca ccaatcccat aaaagcgcaa
     3841 aactttagaa attagttttt cttcagaagg aaaacgttcc tctagtaaag gacgtacttg
     3901 ttccacaaac attggtttca actcattagg cggaccggga agaaggatat acgcatgtgt
     3961 atctgtttga taaaaagtcc ctaaagcaag ccctgtacga tttggtagag gaaccccgcc
     4021 ttcgataatc tgggactgtt gcagattgtt tttggtcatt tttcgatggg ttgtttcaaa
     4081 atatgccaat aattttttgt atccttccgt attttgtatg agagacttac cgaggtgagc
     4141 cgcagttgct tcttttgtca ggtcatcttc tgtcggtcct aatccgccac ataagagtat
     4201 gagttcactt cttgtttcag ctagagcaat caactcttct aaacgctgct gattatctcc
     4261 tacaactgtt tgataataaa cttcgatacc tagatcagct agctgttctg acaagaaagt
     4321 ggcattcgta ttcacgactt gtcctagtaa aagttctgtt ccgacagcta ttatttctgc
     4381 tttcattact tcccgctccc ttatatagta tacgctgtat ttttatattt ttttatttaa
     4441 aaagagggca aggagctgtg acaaaaatct tgtcacagct ccttgttcca aataaacagt
     4501 gttctcctgc caaaacctcg gtcataagtc acaatataca taaaacatga aaagctgttt
     4561 tttgaaatta tcccttgtga ctcagagtta gacggcaggc tcacaacctc tccactaaac
     4621 gatacttaca ttgatccttt gaacacaccg ctgtttttga tgaagtaatc cacacctgaa
     4681 tagatagtaa agatcagaca agcataaagc atgatttgat ctactggaat accgatcagg
     4741 ctgaatggga tattattgat aaacagcaag ataatagcaa ccatttgtgt agccgtcttg
     4801 acttttcccg gccaagctgc agccatgact tctccatgtt cgacaagtag taaacgcaag
     4861 cctgtgacgg ctaattcacg acagacaatg atcgctacta cccaaccagg ggcctttcct
     4921 tggtcaacca acatgataaa agcagtcata actagcattt tatctgccaa cgggtccgca
     4981 aacttgccaa aattagtgac aaggcctcgc gcacgggcaa tttttccatc taaccagtct
     5041 gtgatactag ctaaagcaaa aataactgca cctactagct gtgtgacagc cagtgtggtg
     5101 tctcctacgt taaattgtcc ccaatctaaa ggtaaaccta caaccaaaat gaaaatcggg
     5161 atcatacaaa ttctaagtac agttaattta tttggtaaat tcacactatc gactcctttc
     5221 ttccctattc tacgtgacta tcagcgaagt ttccaccgat attatttact tttccaaatg
     5281 aatttattca aaggagtatt tttattgaaa ttgatctttt tgaattaacg aagaaggacc
     5341 gcgacacaga tttgtcacga tccttctttt ttatacctac aagtaaacag atgcgtaaac
     5401 taatttatac gatcattctg cgtattgaag agtaaggttc acattttttg gactctgatt
     5461 gttttcccct ggattaactg gtacggattc tccattcgct ttgatcgttg cattgcttgc
     5521 tgcaccaatc gtgatggtcg catttgttgc tgtttccggt aacacggtac tctgtgtttc
     5581 atttgctgcc agtgtccctt gataaacata ggcattgtct actagcacac ctaaccatac
     5641 acgattgaca gcagtaaatt caagggttac aggcttggta gcgtctgtga tatttactgc
     5701 gatggcactg ccagaatctt ctcctgtagc tattgccatt ttcttttctt cacttgattt
     5761 tgttgttgat tctactgtag aagactcttt ggtctgcgtg ctttgctctg aggaagagga
     5821 ctcctcgact gatccttcta ctttaagcga agaagctgtg tctccgatta ttggatcagc
     5881 ttgacgatct tgccaagtca tatagcccac gacaacgaca atcgccaaag caaccaatcc
     5941 taataaaatg acaggaagac ttgtccaaaa gcgacttgga tgcgattctt cctgatgcat
     6001 tgcttttcta gaagtactta ctgtttcagg ctgcggacgt tcagggaccg atcctgtcaa
     6061 tttgcttttc ccatcaaaaa catcgactaa atggtctcca tcttctccta cagcttcagc
     6121 gtattgccga ataaatgccc gcacgtaaaa tttaccaggc aattggtcaa aatcatcatt
     6181 gtcgattgct tccaaataac gtttttgaat ttttgtaatc tgctgtaatt catctaaaga
     6241 tattttttta ttcaggcgtg cttgccgtaa tttttctccg atggtttcaa aagccactcg
     6301 ttcatcttct ccagtctgtt tgattctccg aagcatctgc tgttgcaacg aaagacgtta
     6361 tgtttgggtg ctgtgacaaa agtcatgtca cagctccttt tttccgaata aacattgttc
     6421 tcctgccaac tcctcggtca caagtcacaa tatccaataa atataagaag ctgttttttg
     6481 aacttgttcc ttgtgactcg gagttaaacg gcaggctcac gacctctttc ttaaacggtg
     6541 ttcaatcagc tgttcctcgg tattagctca aaaaccggca aaatataagg agatattttt
     6601 ccgtatgttt ctctaatact caggtcaaaa cgctgatttc acaacctctt ccttaaacgg
     6661 tgttcaaaag cttgcatctg cggtaataag tccaaccaag ttaaaaacat taagaagctg
     6721 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctcttggtac
     6781 acggtgttcc agaagtagct tcttcggcaa taagccgaaa tatcacaaaa atttgagaag
     6841 caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac aacctctttg
     6901 attacttcgt ttgattttat tttaatataa gttgattaaa agagagcatg atttgtttta
     6961 ttttctcact aatttttcca acacaactaa gaataccata aaagctgatt ttggaggagg
     7021 ttcctactac aagtctaaaa cgaaatttaa gacttttcct cataaaatac tggtttattt
     7081 tggtctcatg taaaactcgc tgaaggcctc ttcacttata aatgcttccc cagctgccag
     7141 tacgtctttc atttggatcg aatcgatgat ttcaggaaga tcaaataaag ttcgatcgcc
     7201 aaataaactt tgcgtaaatt gattggcaat atattcgatc gaatttaatg attggaaata
     7261 ttgtccaagc attttcttct tcagcaaatc gagatttgtt tctgacactt ccggatcatc
     7321 agcgaatcca agaatgattt ctttgacttt ttctgctgct ttctctggtt cgtccgtatc
     7381 tccgctgaag tccgcaaagt gaaattcacg atccaagctg aattcaaaac caaagctgtc
     7441 atcgataatt ccttgattgt acatcgctag atagtttcga gaagtattgc ctaaaatcat
     7501 ttggaacaac agattgattg ctgttttata gcgtaacagt tctgttcctt cttgcggcaa
     7561 tgtgtctaat cctttaatac caagtacaaa tttatctcgt gtaatggctg cttccaatgc
     7621 actttgtttg atgatttctt ttgtgttttc agggaaataa cgtacaattt cttgctttgg
     7681 agggaaattt tttgcttctt ggttttcccg aataagtttc atcaatttct caggctccat
     7741 cttaccaact acaaataaaa ccatattgct tggctgataa aacgtccgat agcacgtata
     7801 caagtcttga gctgtgattt tgtcgatact ttcaaccgtg cccgcaatat cgatatgcaa
     7861 tgggtgtgta ggatacaagt tatttagtat gccaaaaaac atccgccagt tagggtcgtc
     7921 ttcatacatt tggatttcct gaccgatgat tcctttttcc ttgtttacag tttcttctgt
     7981 gaagtaaggt gcttgtacaa aatcgatcag agtcgtcaga ttcttttcta cctgatccgt
     8041 cgtagaaaac agatagctgg ttttcgtaaa acttgtgaaa gcattggcgg aagctccttg
     8101 tttcccaaat aattgaaaga catcaccatc ttctttttca aacaacttat gttctaaaaa
     8161 atgggcaatt ccatctggaa ctttcacctt ttctttttca ccatagggaa taaattcgtt
     8221 atcgatcgaa ccataattcg tactgaacaa accatatgtc ttgtgatagt catttttagg
     8281 caacaaatac acggtcaaac cgtttggcag tacttcatga taaagtgttt cattgatttg
     8341 ctcatattct gttttattca tttgcatttc ctcctgctaa aaagaagatt gcctgcaatt
     8401 cgatttgctc agctacttgt tgtatctctt tgatcgttac gctctccata cgtttcaacc
     8461 attcttcatc agataatttt gtttccggca gccagctgtc caaaaaagaa gcttcgattg
     8521 ccgcttgcgg agagtctaga gaaagcagat attggtttct cagcattgct tttgtctgag
     8581 acagttccaa ctctgttatt tcaccatttc gcaaactttc taattgctcg tgaatcagat
     8641 gaagtacttg atttcggttc ttttcatcga taccggtttg gacactcatg aatcctcgga
     8701 acgtatccac gctactagag gcataataag ctagactttc tttctctctg acattcatga
     8761 aaagtttaga gtgaggaaaa ccgccaaata aaccgttaaa gaccattagc gcaaaacgtt
     8821 ctggttcatc gtaatacaca tttgtctgat aagctaggtt cagctttgct tgaacgattg
     8881 gctcacgtac ttgtcgttcc ttcacgatat tcacttgagg ttgggtataa aacagatctg
     8941 gataaactgt ttcccgcgac tcaaatggta attgcccaac tgcttcagct gctttgtccg
     9001 gatcaacatc gccgacaaca aaaatgtcga tttgatcatt tgccatcatt tcttgatagt
     9061 aggacgctag cgaactagca gtgatcttgt ccaaatcttc gactacgccc aaccctggga
     9121 tcttttgttc cgggctgttt tcaaaataaa gttcttgcaa ggcataggaa gcaaaagttt
     9181 gtttatcttc cttcaaactt tccaaatata gacgcagatt gttcttttcc aagtcaaacg
     9241 tcaactgatc aaactgatga tttttaatat ttggataaaa taaaacctct tttaaaaaat
     9301 ctaccgcttg agaaaaaagg tttggatcat tgacatattc accattcaca aaactgatcc
     9361 ctgcgtttag ccaatgtaaa tttccttttt ttctaactga taatccaaag cttgcgccat
     9421 aaagctctgc aagttgcgca cttaactttg tctgatccgg ataattcaaa ctatttgttt
     9481 ccaacatgct gctgagaagt gaacgtttcg tgatgacttc ttgttgcaga cgcgcagtaa
     9541 aacggataaa aatccggatc gttttgtatt gttttgttgg taagacatga agattcacgc
     9601 cttctgccaa ttgatacacc atatttatat gctccttttc acagttgatt gcccgcttac
     9661 tcttttaatg ggtcaacctg ccttttttac ttattcctct gcttgaaatt tataagttca
     9721 ggcaattcgc cgttttttct aaatgatgtt acactttata gtatagcata gatgtttttt
     9781 atcaaaagaa acagacggct aaaagcgtat attgtttttt tattttttat ttttcgatat
     9841 actaaagaca aataaaagaa gggagggtca ttcatgatca aagaattcaa agagttcatc
     9901 atgcgtggag atgtcttgga tcttgctgtc ggcgttgtta ttggtagtgc gtttacaagc
     9961 atcgtaaacc aagtggtgca aggcttgatc acaccactaa taggttggtt tgtcgcaatg
    10021 atcacaggta cttctgattt agaaggagca ctttcaattc ttgactggtc gccgacaaaa
    10081 ggcgtcacat ttgcgtttgg taacgttatt agtgctatca ttacatttct gatcactggt
    10141 tttgtcttat tcttagttgt caaagcggca aaccgtgcga agaatttacg ctccaaagaa
    10201 gagcaagtgg aagtggaaga aactcctact gcagaagatt atcttagtga catacgcgat
    10261 cttcttgcca aacaagtggc agaagacaat acacatccag tagagcaaac aaatctttcc
    10321 gatacttcta aataataaag aatctaaaaa aaagaaagcc gattttcagt gtcggctttc
    10381 tttttttaga ttcttaactt gctacttgtt cctttttcat gtcgatatgt ggaatatcat
    10441 cttccaaata cacatctgag attgccttga atccaaacga ctcataaaaa gcttgtaggt
    10501 attcttgtgc gccgatcacg attggttttt ctggaaaatt tttctggatc atgttaatcg
    10561 tttcttgaac aatctttctt cctaaaccat ctttacggtt gtcctgatga acaaggacac
    10621 gtccaaaatg gatactctcc gcttcttcat atactcgcgt gtaggcaagg atcttcccat
    10681 cagtatcttg aaaaaacgta tgccaagctt gtccatcaat gtcatcaact tcttgataag
    10741 gacactgttg ttccacaaca aaaactgcga ttcgttcttt gacgatcgcg taaaactctg
    10801 ctgttgacaa ttcttcaaat ttctttacct gatattccac taagcaaacg ccccctgctt
    10861 ttttattctt agcataccga ttcgcacaca aaaaagcaaa cgaaccttac gaatctcagg
    10921 ctcgtttgct ttttaaactg cttcagttaa aaattcgatc tcaactgtcc gagtaagtac
    10981 atctgaatag ctgtaagata ctcgttcaaa agaattttct tcaggatcca aatcaacaac
    11041 gaatactgaa ggataggttt ctgttaaaac gccgcggcgt tctgtttgac gctttcttcc
    11101 tgtctgagca accaacatga ttgggctgcc gatacgacct tctaaatctt tcttgattga
    11161 agctaaagtt gttggcatac agttcacctc tactatcaac tataccacat atttttaaaa
    11221 ttttcaagtt taccataaaa aaaaagaaat gcaataaaaa taaataagaa gctcattaag
    11281 atttttctaa attattcctc attataaaat ttcaagtgtt tttttatttt gagttttact
    11341 ctcccgtaag cgctcattac ttgcttgtga tccattgcta aacattcagc catgtctaca
    11401 aaatcaacgc cttgcatata ataatgaaaa attttagctt ctatttttga aaactggatt
    11461 tcgcaatttt cgattgcttc ttttaataaa agatgctgaa tcgctaaagg ttcttgcaat
    11521 gtgatctctg ctaaaaagtc tggtccttct gtctctattt tttggtcgat tgagacttca
    11581 tctttttgat cacgacgctt cagcgcgttc tgcttcctca acagagaata gatttgattg
    11641 cttataatgc ttttataata acttccaaag ctaacacctt tgcttttttc gtaagttctc
    11701 aatgcctgat ataaagcgat ccttgcttct tgttcccaat cctcagaaac ataatttctt
    11761 aaataatagg tgtttttcaa acgtagtaaa agtggaaaat atttttgata cagggcagca
    11821 aatgcttctt cgtcaccatt acgtgcagcg cgcaataact cctcagacat aaaataattc
    11881 ctccataaat tcgtttatgg aggaatctta tcatcaatga ttcatcgaac tgattagaac
    11941 gatatgttat ttattttttc tcattaaatc gtccaatttt tgggacaatt tttttaactg
    12001 ctcttcattc catggagaat tacgtcggaa atcaataaaa tgcatatctt tattttcttg
    12061 ggctattgtt ttttccgttt tttttatcgt cttatataat tcataagcag aagttcgtaa
    12121 tgctccttgg gaaaagatca tccactgttc tgctaaatcg cttgtcgcca ctgtcacttg
    12181 tgtcaaacgg tcattcagct gaccagcgat tctctcgata taactgtcag ccgtttcgtc
    12241 ttctttcgta aaaacaacat ccaactggta tttcttataa ttttgttgga tgcccggaac
    12301 tagttgggca tcgaagacaa cgatgacttc cattccttca tatttcgcat aatttgataa
    12361 acgatgtaaa agagcttctc ttgcatccgc cattttgtcc tgctttttaa gctggacaag
    12421 ttccggccac gaaccaatca tgttgtagcc gtctacaatc aacagctgtt ttttcatggt
    12481 ctactccccc tgacgttggg aaaaagcctg atacataagc aaaccagcag caacactggc
    12541 atttaagctc tggacgtgcc cggtcatcgg gatcgtcagc aattcatcca tttctttttt
    12601 caatcctgga ctcattcctt tgccttcatt accaatgact aaagcaattg atcctttggc
    12661 attccatttt tggaagtttg tgccggtcat atctgtgcca aatacccaaa atcctgtttc
    12721 tttgagctgt tgcacagctt gtaccaaatt cgtcacgcgt gcaacaggga catgttcgac
    12781 tgccccagtg gaagtctttg ttacgatagg tgtgattcca actgctcggt gttttggtat
    12841 gatcacacca tcgacgccac ttgcgtctgc tgtccgtaaa atcgacccaa aattgtgtgg
    12901 atcttcgatg ctatccaaaa tcaaaaagaa ggggtcttct tttttctctt ttgttcgttc
    12961 aatcagttgg tcaagggata aatattcata aggtgtaatc gcaagaacga ctccttgatg
    13021 cacgccgtga tcgctcaaag tttctaattt ttgtttagga acccatttga ctggcacagc
    13081 ttgttcacgt gcgatttctt tcagttcttc tactttttct cctcgtgaat cttcttgaag
    13141 aaagagttta ttccctcgcc cttgttgtag cgcttctact gcggcatggt gcccaaagac
    13201 gaaattatct tctaatgctt cttcattttg atcagaaact gactgatttc gtccagtttg
    13261 ctttttattt gaatatctat tttgtttttt gtcttcaaat ccacgtttcg attgatgttt
    13321 gtttgttctt tctttaccca tttttttcac caactttctg aatacaccag cggatcaatt
    13381 cttccatccg ctcggtttgt tttgtcaaat gcagatagcc catgagcgct tcgaaccctg
    13441 ttgcgacccg atacgtcgta acatcagcat tttttgcgct cgtatggctt ttagcatttc
    13501 ttcctctgcg ataataaagt tcttcttctt ctgtcaaaag atgttcttcc agcatttgct
    13561 gaatcaaaaa ggcttgtgca ttcgcagaaa cataattcgt tgccgcacga tgcagcttat
    13621 tgggttttgt ttctccttga tcaatcaggt ggtcacgaac atagatttcg taaatcgcat
    13681 ctccaacata agccaaggct aaaccgttca attgtgtgta atctctcatg cttctcttct
    13741 ccatcgggtt ccttgcggtg tatcttctaa taagatccct ttttctttca acaaatcacg
    13801 aatttcgtcg cttcggacaa aatcacgatt gcttcttgct tgatttcgtt cttcgatcaa
    13861 ttgttcaatc tcttcatcta ataactcttc tgctgtaaat aaaataccga agatcgaaag
    13921 ccattgcgag aataaagctt ctccttgtgc caagacagcg gcagaaactt tcggctggtc
    13981 tagataagtg ttcagccact tagcaagctc atagaccact gtgatcccat ttgctgcatt
    14041 aaaatcatcg tccatttctt cgatgaatcg ctgttctaaa ttttctaaca aagcgatttt
    14101 atccgcatca tctgccaaat tctctgaggc agtttcttgg cggaatttca aattgtcaaa
    14161 cgtattcttc agtcgttgta aattggtggc tgcttctttc atcgtcgttt cactgtagcg
    14221 gatcggacga cggtattgtg tggtcgccat gaagaaacgc aagacttgtg gatcaacgtt
    14281 tttgatcatt tcatgtacag tgatgaaatt ccctagagat ttactcattt tttcatcgtc
    14341 ttcgccaatc gttacatagc cattgtgcat ccagtaatta gcgaattttt tccctgtttt
    14401 cgcttcactt tgtgcgattt cattttcatg atgaggaaat tctaaatctt gcccgccacc
    14461 atggatatcg atcgtttctc ctaaatgttt tgttgccata acggaacatt caatatgcca
    14521 accgggacgt cctttgcccc atggtgaatc ccaagaaatc tcgccaggtt ttgcttgttt
    14581 ccataaagcg aaatctaatg ggtcttcttt ttgctgctgt tcttcccctg tacgctgact
    14641 tgctccgact tccagttcat cgatggattg gtcacttaat ttcccataat tttcaaattt
    14701 acgggtacgg taatacacat cacctgaaga ttcataagca tagccttttt caaccaacac
    14761 ttgaataaat gctaaaatat ctggcatatg atccatgact cttggatgca gtgtagcagg
    14821 ctcgacattc aacgctttcg tatcttcttc aaatgctcgg atgaaacgat cagcaacttc
    14881 tggtgctgta atacctaatt cgtttgctgt acggatgatt ttatcgtcta catccgtgaa
    14941 attcgatacg aaatcgactt tatagcctcg atattcaaaa tagcgtcgaa ttgtatcgaa
    15001 agcaatggtg ctacgagcat ttccgatatg gatataatta tacacagtcg gtccgcagac
    15061 atacataccg acatgtccct tttgtatagg gatgaattct tctttttttc tggtcaatgt
    15121 attgtagatt tttatcattc tgatctcctc actttttctc ctttgattcg aacgactttt
    15181 gctggtactc ctaccgctgt agcgtcgtct ggaacatctt tcaacacaac ggcacctgca
    15241 ccgattttgg cgttttttcc gatcgttacc ggtcctaata tctgcgcatt cgcagagagc
    15301 atggctcctt gtttaacagt tgggtgtctt ttacccgttt cttttcctgt gccgcctaat
    15361 gttacgccat ggaataaaat cacatcgtcc tcgatttctg cggtttcgcc aatgacgatt
    15421 cccattccat ggtcgatgaa cacgccagtt ccaatcgttg ctcctggatg gatctcaaca
    15481 ccagttagga aacgccagaa ttgagcattg atcttcgcca ataaaaagag ccggtgctga
    15541 tataaaaaat gagagaaacg atgccaaaac aaggcatgaa aaccagggta tgtcaaaacg
    15601 atctcagctg tcgaacgtgc agccggatcg tttctctttg ctgcatcaat cgctcgggta
    15661 aaccaactca tgactttcca ctcctttcgt aagaatttta tgtaggaaat catcttctta
    15721 taaagaaaag aagcgccttt taaataagtt tccttatcaa aagacgcttt ccgcgtggtt
    15781 ccacttttct tcataatcaa tgattatctc tgacagctaa cgcctgttat acgttcttgg
    15841 ctactttgtt tcctataaaa cagtttttcc tgttttctgt gtttcgccaa gaccactccc
    15901 agaggcattt cggcaaccat tcattgatac cttgcaccac ccggtatctc tcttgtaatg
    15961 atcagctgct tacttttttc tgttcatcgt gtttagttca gtacttgatt taaatgtgct
    16021 aatgattttt cacgaccaag caattcgatc gtttcaggca attctggacc atgcatttgt
    16081 cctgatacag ctacacggat tggcatgaaa agattttttc cttttacgcc agtttctttt
    16141 tgaacagctt tgatggcagc tttgacagtt ggagcatcta ctacttccat ttgttctagc
    16201 tgtgctttga atgcgtggag aacagtagga actgtttcac cagcaagtac ttcttttgct
    16261 gcttcattca atacaggatg ttcattgaaa aatagcgtag acagatcaac gatttctgca
    16321 gcatagctca tttgaggttg atacaggcta acgatcttct tcacccattc gattgtcttt
    16381 tcatctgggt tttctgctac acgtccatca gcgattagat aaggcagaca catgtcagta
    16441 aatgcatcta gatccattgc tttgatgtaa tggttgttta cccattgcag ttttttcgca
    16501 tcgaaagctg cgggtgattt acttaggcgt tttggatcga acattttgat caattcttgg
    16561 tgttcgaaga tttcgtcttc gcccacaggt gaccagccca ataatgcaat aaagttgaac
    16621 attgcatctg gtagatagcc taattcgcga tattgttcga taaattgcaa gattgattcg
    16681 tcacgtttgc ttagtttttt acctgtttca ctgttgatga tcaatgtcat atgtccgaag
    16741 gttggtggtg tccagccaaa tgcttcatag atcatcagtt gttttggtgt attggcaata
    16801 tggtcatctc cacgtaaaac gtgagtgatt ttcatcaaat gatcatcgac cgcaacagca
    16861 aaattataag ttggcatacc atcgcgtttt tgtatgacaa agtcgccacc gatattatcg
    16921 gattcgaacg aaatagcgcc tttcaccata tctgtaaatg cgtattctgt attgcgaggc
    16981 acacggaaac gtacaacaga ttctagacct tgtgcttctt tttctgcttg ttcttcaggt
    17041 gtcaagttcg cacatgttcc tgcgtaatga ggcatttctc ctcttgcgcg ttgtgcttcc
    17101 cgttctgctt ctaattcttc ttctgtgcaa tagcatttgt atgctcgatt gctagcaagc
    17161 agctgatcaa tcagcggttg atagatttct ttacgttcag attgacggta agggccgtat
    17221 tctccaggat tttcaggaga ttcatcccaa ttcattccca accaagcaag gttttccaac
    17281 tggctttttt cgccatcttc gatattacgt ttttggtcag tatcctcaat acgaataata
    17341 aagtctccat cattgtggcg ggcaaacaaa taattgaata atgcagttct tgcatttcca
    17401 atatgcaggt gcccagttgg acttggtgca tagcgtacgc gtactttcgt cattttcttc
    17461 ctcttctttc aaactagact ttgactaaca gcaaaaattc cgtcagttac ggcttctcaa
    17521 atatcattta tttaaagcca ctcagcacaa attttacctt ttctaaggta aatagtaaag
    17581 ccaactggtt gaatttcctt accagttggc tgaatttctt ttttattttg attgtttagt
    17641 ctttttctct gtctcttttt tattgtcgat tcctcgtcct gcatgtgcag gtttagcaaa
    17701 gatcatgcgt ccagcagctg tttgaagggc acttgttaca acgacttcga tacgttcatt
    17761 catgtaatgc tgtccatctt ctacgacaac catcgtgccg tcatcaaggt aggctactcc
    17821 ttgttggcgt tctgtcccgg cttttactac tagaacattc atcgtttcac cagggatgac
    17881 gactggtttt acggcatttg ccaacgcatt gatattaaga acaggtacat tttggaattc
    17941 agagacttta ttcaagttat agtcattggt tacaatgaca ccatctaaaa gcttagccaa
    18001 tttgatcaat ttgctgtcta cttcactgat atcttcaaag tctccatcgt acatttcgac
    18061 agatataccc tcttcttttt gcaaggcatt taggatatct aatccgcgac gaccacgcac
    18121 acgtttcaaa ctatcccctg agtccgcgat gtattgtagt tcgtaaagaa caaaattagg
    18181 gatcatcaag gttccttcta agaatccagt ctttgtaata tcataaatcc gaccgtcaat
    18241 gatcacgctt gtatccaaga ttttatattt atggaaattt tctcctgatt ttcgttctaa
    18301 cagttgactc tcaacttgac tagctgtttc ttgctcgatt tttttgcttc gtgaaccaaa
    18361 aactttcttc cattcttcga ttcgtgtcgt tcccattctc aatcccagat agcctaagat
    18421 gatcatcagt aaaatcggca atacactatt gacgaatgga atttccatat tgtaaagagg
    18481 ggtcgagatc acaacaccta aagtcaatcc gatgatcgca ccgatcgcac cgaagagaag
    18541 ataagtcaag ctgacctcac ttagtttttg ttctacttgt ttgataatag ctgagatatg
    18601 tttggccaac agcaaagata ataaaaagaa aataagtgcg cctaacaggc tgttggtaaa
    18661 tgtattattc agccatccgt ttgactgttg accgattgcc tgccaagctg agggtaaaaa
    18721 tgaaataccc aagcttgcgc cgacaatgat catcagcaaa gtaatgacac gtttttgcat
    18781 cgtttttcct ccgtttcgac aatcatttat tagttagcgg aacacacgct tcaacgtttc
    18841 agccaaagtt gctactccaa ctatctcgat tccttttggc gcttcccagt tacctaagtt
    18901 gtttttaggt aggtatactt ttgtgaagcc gagtttttgg acttctttga ctcgttgttc
    18961 aatatgactg acacgtctga tttctccagt cagtccaatt tcaccgatga aacattccgt
    19021 tggctgtgtt cctttttctt tatagcttga agcaatactg acagcgatag ctaaatcaat
    19081 cgctggttca tttaatttta ccccacctgc agcttttaag taagcatctt gattctgaag
    19141 aagcaaccca gctctttttt ccagcactgc catgatcaga gatacccgat tgaaatcaag
    19201 acctgttgtt gttcgtttgg catttccgaa catagtaggt gtgactaatg cttggatctc
    19261 taccaaaatt ggacgtgtcc cttccattgc cacaacgata gcagagccag ttgcaccgtc
    19321 taggcgttct tctaagaaaa tctgtgaagg attagcgact tcttccaatc catgctcatg
    19381 catttcaaaa atcccaatct cattcgttga gccaaatcgg ttttttactg ctcgcaaaat
    19441 ccgaaaacta tgatgttgtt caccttcaaa atataacacc gtatccacca tatgttctaa
    19501 cattcttggg ccggcgatcg agccttcttt ggtaacatga ccgacgataa aaatggctat
    19561 cccatttgtt ttagcgattt tgagtagttc tgcagtggtt tctcttactt ggctgacact
    19621 tcctgccaca cttgtgatgt ctggctgcgt catcgtttgg atggaatcaa tgataacata
    19681 atcaggggag atatgttcga tggcacgact gatttcgttc atatctgttt cagcgtatag
    19741 ataaaattct gtgttgatac ttccgaggcg ttccgcgcgt aattttatct gctctgcgct
    19801 ttcttcgccg gatacatata agacttttcc gcctatggct gctaattgct gagaaacttg
    19861 taacagcaaa gtggatttcc cgatacctgg atcgccacca atcaagacca tagaccctgg
    19921 caccacacct ccgcctaaca cacggttcag ttcttctaat tttgttttga tccgaggttc
    19981 ttttttaggg acgacgtctg cgatttttgt tggttttgct ttttctcctg tcaaacttgt
    20041 ccgagttctg cggtccgttg tatcttgttc gatttcttcg accatcgtat tccattttcc
    20101 gcaatttggg cagcgtccca agaacttagg cgacacatac ccgcaatttt ggcaaacaaa
    20161 ttgtactttt gatttttttg ccattgtacc gcctcctttt atcctaatca tgagacatta
    20221 aatcaagctt aagtatcttt aacgttttat ttactggaag aaccaaatcc gccttgacgt
    20281 tgagcagtcg tttgatcttg atctgctttt aaaaacggca aaaagatccc ttggccgata
    20341 cgctcgcctt ttttgatcac tacatccttg aaaccaaagt tggtgaattg gaacatgata
    20401 tggccttcat ttgcctcatt attgtaataa tcactgtcaa tcacacctac tccgtttgtc
    20461 aacactaaaa accgcttcaa cggattgctt gaacggttag caagctgcaa aaattcatct
    20521 tctcccatgt aagctttgat tccagtaggc acgagggttg gtttcaattg tttttcattt
    20581 tctgatacat cttttttcaa tccatctgcg actgtttcca accccttttt ccagcctgct
    20641 ttccagatac ttggaatcac gacctcttct gctgcttcaa aatcatagcc agcagcatga
    20701 tgtgtagcgc gctgcggtag attgatattt tgatctttat atttagaaat aacttcaaat
    20761 cctctttttc tcaccggttt tcct
//
LOCUS       DAFEIE010000044        20285 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFEIE010000044
VERSION     DAFEIE010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.045"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            140..460
                     /locus_tag="LP345_001875"
     CDS             140..460
                     /locus_tag="LP345_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760654.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            912..1112
                     /locus_tag="LP345_001876"
     CDS             912..1112
                     /locus_tag="LP345_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1760655.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1259..4048
                     /locus_tag="LP345_001877"
     CDS             1259..4048
                     /locus_tag="LP345_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL1760656.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4095..4622
                     /locus_tag="LP345_001878"
     CDS             4095..4622
                     /locus_tag="LP345_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBL1760657.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4643..5833
                     /locus_tag="LP345_001879"
     CDS             4643..5833
                     /locus_tag="LP345_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1760658.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5873..7171
                     /gene="asnS"
                     /locus_tag="LP345_001880"
     CDS             5873..7171
                     /gene="asnS"
                     /locus_tag="LP345_001880"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBL1760659.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8224..8898
                     /locus_tag="LP345_001881"
     CDS             8224..8898
                     /locus_tag="LP345_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL1760660.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8895..9236
                     /locus_tag="LP345_001882"
     CDS             8895..9236
                     /locus_tag="LP345_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760661.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9266..9625
                     /locus_tag="LP345_001883"
     CDS             9266..9625
                     /locus_tag="LP345_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBL1760662.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10149..12230
                     /gene="cadA"
                     /locus_tag="LP345_001884"
     CDS             10149..12230
                     /gene="cadA"
                     /locus_tag="LP345_001884"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL1760663.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12541..14007
                     /locus_tag="LP345_001885"
     CDS             12541..14007
                     /locus_tag="LP345_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1760664.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            14622..15161
                     /locus_tag="LP345_001886"
     CDS             14622..15161
                     /locus_tag="LP345_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HBL1760665.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            15235..15675
                     /locus_tag="LP345_001887"
     CDS             15235..15675
                     /locus_tag="LP345_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBL1760666.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            15688..15897
                     /gene="copZ"
                     /locus_tag="LP345_001888"
     CDS             15688..15897
                     /gene="copZ"
                     /locus_tag="LP345_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBL1760667.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            15897..18083
                     /locus_tag="LP345_001889"
     CDS             15897..18083
                     /locus_tag="LP345_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBL1760668.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            18103..20274
                     /gene="copB"
                     /locus_tag="LP345_001890"
     CDS             18103..20274
                     /gene="copB"
                     /locus_tag="LP345_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBL1760669.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6776 a         3527 c         4407 g         5575 t
ORIGIN      
        1 aaaaagaggt tgtgacgtgg tcacgacctc tttttgacga ttatgataca aaaaacatca
       61 tttatgaaca aaatgtgaat aacgggcgtt cttgagatat gattttaatt gggaaaaact
      121 tatcgataag gaggtcttta tgaaaaaaag actgttatgg tgtttgctgt ttctatccct
      181 aagtttaaca agtcagccag tttttgctga agaaacacag cggtctccta ttacaggcac
      241 acgtctgtac aaaaatgttt atgtacagac aacagatctt gattctgcga ttcctgaaac
      301 agaagaacgg tctttgcagc caagatttgg ttacttttgg tactgtccga cctgtgatta
      361 tgaaagttgc tggcatttct tacattctac agctgcagct tttgctttta ctcatactca
      421 gaaatatgat ggacatcatc ctgttattta tgaggtatag atatgagcaa aaaagaaaaa
      481 ctaatctcgt tgatcgtatt ggtttgcctt gttcttctgg taactgtcat aggctatcag
      541 aaataccatg agaacatcag acctactaaa gaatcttccc cagcctcgac cgttgaaaca
      601 gaaccgataa gtagtcagaa agaataattt ttttagttta aagaagaaca tcagagcaaa
      661 aaaacaccaa ctgaacaata tgtcgtttat tttaaaaaaa gttcggtttt tcactttatg
      721 taatcgctga gaaaactttt tttaataaaa aaagtcgaaa aactctagct tttttgtaaa
      781 cggtatgata tactatagga gtagtttttg ttcggtaatc tgtggtagct tgtttcaaat
      841 aaacatcttc cagatataca ccattcaagt aattgcaaaa tatgtgttga tacacaagga
      901 ggatttttat tatggaaaca ggtacagtaa aatggtttaa ctcagaaaaa ggatttggat
      961 tcatcactgc agaaaacgga aacgatgtat tcgttcattt ctcagctatc caaggcgacg
     1021 gattcaaaac tttagaagaa ggccaagcag taactttcga tgttgaagaa ggccaacgcg
     1081 gacctcaagc aacaaacgtt actaaagctt aattaaccta tactaaaaaa taaacgccca
     1141 gacatttgcg tgtctgggcg tttttgtcta ttttctttaa aaagcgatga gagtattttt
     1201 ctgcactttg tagtataatt tcaaaagaac attagaggca ggagaagagg aagatatttt
     1261 gaaaccaaga acttatgcag tcgttgatat cgaaacgact gggacgaatc caaaagaaga
     1321 tcggatcatc caatttggct gcgtcatgat tgaatcaggt cggatcactt cacgtttttc
     1381 gatcgatatt catccagggc ggaagatttc aaaacaaatc cagcatttaa cagggatcac
     1441 gaatcaacgc gtccaaaaag cgccttattt cgaagatgtc gcccaaacga tttacaatct
     1501 tttggcagac accatatttg tcgcgcataa tatttatttt gattataatt ttttgaacca
     1561 tgaactcatg cgatgcggac ttcctagttt gaagatacca ggcatcgata cagtagaact
     1621 tgcacaaatt ttcttgccga cggaaccaag ctttcgctta gctgatttgt cagaaagcct
     1681 tggatttatt catgagaatc ctcatcaggc agatagtgat gccgaagtga cgggtcaact
     1741 tcttttgctg atcgaagaac ggatgagaaa attgccaatc atcacgttag agcagattgc
     1801 gcgattaagt agacacacag gtatggatac gagtcgtttc atttatcatg tgattgaaga
     1861 aatgaaagaa aaaccagagc cacttgatcc ctcattagaa atcgtcgatg ggctagcttt
     1921 gcagaaaaaa gaagtggaac tattcacatc cgtccattat ggcgagcgga catatccaag
     1981 aaaaaaacaa gcaaaagaaa aaatgtttgg taaaacactg atgtatcgaa aagaacagaa
     2041 cagactgatg aatgcggtct acgaccattt cacaaaagat gaatcaaaag atttgatgat
     2101 cgaagcagct acaggaatgg gtaaaacaat cggttatctg ctgccattga gttatttggc
     2161 tacacctgaa aaacccgctg tcatcagtac cgtttcgcta gttttgcagc agcagatcat
     2221 agaaaaagac attccattgc tgaatcaatt gctagatcag cccatacaac ctgtaattat
     2281 caaaagctat cgccactata ttgatttaca gcgttttaaa ggcacacttg tggaaccgcc
     2341 agaacaaaaa caatatgctt tgtatcaaat ggcggtctta gtttggctga cgcaaacgaa
     2401 gaccggtgat ttggatgaat tacatttaac aaatttgaac cattcattct ttgcagatat
     2461 cgcgcacaga ggtattggat ttttagcaag aaatcagtca ttttacgaac aagactttgt
     2521 tcgtttcttg caaaagaaaa tcaggcaaag taattttttg attgtcaatc atgcgttttt
     2581 aatacaagaa acacagcgaa aagaaccatt gcttccagct agtccatttt tgttgatcga
     2641 tgaagtacat catttgccgg aaatcgctga aaaagtaaat gacaaacgat taagtattaa
     2701 ctatttccat aaacaaatcc agcaattaga agaaccaaat cagctgtttg accgaataca
     2761 aagctattta ccgaaagaac atgaagcctt acgctggtta tcgatttatc gagaagaact
     2821 ttctgcgcta tgcgaagcac agatttgtat ggcagaagga ttaatgagtt tagtgagcgg
     2881 caagcaacct aacggacagt atccagaaga agtcatgatg acaaaagaga tgttggatca
     2941 gctgccactg gaatctggga cagccattga tcacctgcag cttttttatc aggagatcca
     3001 gcagctacag tcacaaatgc gtctgacttt tgagattatc caagaaagct ggacaaacca
     3061 gatgcggatc gatttagcaa gtttatatag cttatttgat caattagaca agcagtactt
     3121 gctgatggat caatggctgg aagactggcg agatcatttg atccattggt tcgttcctgg
     3181 gaacacagcg cagcagatga tttttcatct ccatgatttt caagcggcta tgttgccgtc
     3241 gactgtttgg tatcctcgat atgatcgtat tctttatatt ggaggaacgc tgaagatcgg
     3301 ccctaatcga cactatctct ctaagcggct tggcattgaa gcagcacctc ttaaagtgat
     3361 tgcctctcct tatgattatg agaaacaggc aaggatctat gtgccaaaag aggcacctgc
     3421 cgtccatcaa gtcagcaatc aagcatatat cgattattta gagacagcac ttacaggtct
     3481 gatcgaacaa gaagatcggc caatacttgt gttattcact tctcatgatg ttttgcagaa
     3541 ggtctatcag aaaatgcatc tgtctatgct agaaaaagga cgagaaatac tagctcaagg
     3601 gtttggcgga agccgggaga agcttttgaa acgcttcatt ttgtcagaaa aaagcgtatt
     3661 gtttggcgct gacagctttt gggaaggtgt agatttgcct ggggatgctt tgcagatcgt
     3721 tgtagtcaca cgtttaccct tcgataatcc gcttcgcccg atggtcaaag ctaggaacgc
     3781 ttatttagaa tcagagggga tcaatccttt ttaccaggaa tccgtaccta aagcagcttt
     3841 gaagttacgc caagcattag gtcgcttgat aaggacggag acagatcgtg gcgtattgct
     3901 tattttggat cgaagactag tcactgcaaa atatggtgca cggatcatcc atgcattacc
     3961 gaaaaaagta ccgatcaaag agctagctat ggaggaaatc tatcaggaca tccatgaatt
     4021 cttaaagaaa aatgaagaag gaagttagag gagctgtctt ttttcataat taaaatctgc
     4081 tataatgaaa aggaatgaag ataaaggagc gacgaccctt gaagaaaaaa cagacaaagg
     4141 aaaaaacgat taatcgcgtg ttacttggct tgatcgtatt tttattagcg gtcatcgtga
     4201 tcagctcgat tttttacttg cgttccagtc gtccggcggt gcaggcgaag aaagaagcag
     4261 tagaaatcgc aaagaaatat gcaaatcttg aggaagccga tcatttttat tggtttactc
     4321 gaaagaagac atacttttca ctgacaggta caaatgataa aggaaaagaa atcgccgtta
     4381 tcattcctaa atctggtgaa aaagtaaaag tattggatca aacaaaggga ctgactgaaa
     4441 acgaagcaaa acagacaatt gctgcggccc atcctgaaat ccaaatcgaa aaagctgctt
     4501 tagggatgta tgatgatcag cctgtgtggg aagtagtagg aaaagaaaca aatgggaaac
     4561 tgaattatta cctgattggc tttgaatctg gagatgaagt caagacaatc aagggaattt
     4621 aaaaggtaaa ggaatgaatg ggatggagtt atcaaaaaga acaaaacgat tagaaccgtc
     4681 tgtcactttg gcagctgcgg caaaggccaa ggcattaaaa gcaaaaggca gagatgtgct
     4741 gagtttgact gtgggagaac cggattttgc gacaccagaa aacatccaag aagcagcaat
     4801 cgaagcaatc cgcaacggga aagctagcta ttatacacca acagcaggaa tcccagagct
     4861 tcgacaggca atcgttgatt atctgaagaa aaactatgga cttgtctatg aaccttcaca
     4921 aacagtcgta acagacggag cgaaatttgc tttgtatacc cttttccaaa cgatccttga
     4981 cccgcaagat gaagtcatca ttcctgtgcc ttactgggtc agttacggtg agcaagtaaa
     5041 actggcagaa ggacttcctg tctttgtgaa aggggaagaa tccaatagct ggaaagttac
     5101 tgttgaacag ctagaacaag cacgttcaga aaaaacaaaa gccgtaatca tcaattctcc
     5161 atcgaatccg actggaatga tttatagcaa gaatgaactg caggcaatcg gtgaatgggc
     5221 agtaaaaaat gatattttga tagttgctga tgatatttat ggtcgtttag tttataatgg
     5281 caatgagttt actccaattg caacgatttc agaagcaatc aaaaatcaga ctatcatcat
     5341 caacggcgtg tctaaaacat atgcgatgac aggctggcgc attggttatg cggtgggaaa
     5401 tcctgtgatc atcaatggaa tgatcgctgt tgcttcccag tcaaccagta atccgacagc
     5461 agtcagtcaa tatgcagctg ttgaagcatt gaaaggcgag caagatacag tggaagaaat
     5521 gcggaacgcc tttgaagaac gcctgaatac gttatattcg cttgtggcag aactgccggg
     5581 tgtttctctt gaaaagccac aaggagcttt ttatcttttt cctaatgtaa aagaaacgct
     5641 acgcatgtgt aaatatgaaa atgtcacaca atgggtagaa gatcttttag aagaaacagg
     5701 ggtagcgctt gtgactggcg aaggctttgg ggcaccagaa aatgtccgca tgagttatgc
     5761 tactgatcgc gctacgttag aagaagcggt acgcagaatc aagcaattta ttgagagtaa
     5821 aagtcaaaat taatcctaaa gaaattcaag gaatataaaa ggagagtcat acgtggaaca
     5881 aattcaaatc atcgattcga aaaaccatgt gggagaaaca gtaacaatcg gcgcttgggt
     5941 cgcaaataag cgatcaagcg gaaaaatcgc atttttacaa ttaagagacg gaacagcctt
     6001 tttccaaggt gtagttgtaa aaagcgaagt gtcggaagaa gttttccaaa cagctaaaaa
     6061 tctacaccaa gaaacatccg tgttagtaac tggagaaatc cgtgaagaca gtcgttcaaa
     6121 atttggttat gaaatcggaa ttacaaatgt ggaagtggta agcgagagcc acgattatcc
     6181 gatcacacca aaagaacacg gaacagactt cttgatggat catcgtcatt tatggctgcg
     6241 ttcttcaaga caacatgcga ttatgcagat cagaaatgaa atcattcgtg caacgtatga
     6301 attctttaat caacatcatt ttgtcaaaat tgatccgccg atcttgactg gttctgcacc
     6361 agaaggcact acggatctat tcgaaacaaa ttactttgat caaaaagctt atttatctca
     6421 aagtggccaa ttatacatgg aagctgctgc tatggctttc ggaaaagtct tttcattcgg
     6481 tccgactttc cgtgctgaaa aatcaaaaac acgacgtcat ttgatcgaat tctggatgat
     6541 cgaaccagaa atggctttca ctcatcaaga agaaagttta gaagtacagg aacaatatgt
     6601 agcattctta gtacaaaatg ttttagatca ttgcgaatat gcattagatg tactaggacg
     6661 agacaaagaa gtcttaaaaa cttatacaaa attgccattc cctcgtatta cttatgatga
     6721 tgcgatcgaa ttactgaaga aaaatggatt tgatgacatc gaatggggcg aagactttgg
     6781 ttcacctcat gaaacgttca ttgcgaattc attcgaacag cctgtcttta tcctaaacta
     6841 tccaaaagcc atcaagccat tctacatgaa accacatcca acaagagaag acgtggtgat
     6901 ctgtgcagat atgatcgcac cagaaggtta cggtgaaatt attggcggaa gcgaacgggc
     6961 aacagactat gatttcttgc tagaacaaat ccgtaatcac ggtttggatg aaaaagaata
     7021 ttcatggtat cttgatctac gtaaatacgg ttctgttccg cactctggtt ttggtctagg
     7081 tcttgaacga acagtcactt ggattgctgg tatcgaccat gtacgtgaag ctattccatt
     7141 cccacgtttg ttgaaccgaa tttatccata agaggtgatg aaaaagctgt tctgcatcaa
     7201 gtaattagaa cagccaagca aaaacagctg ttcatgtttt tgaattggcg ggacttatta
     7261 ccgcagatgt aagcttttga ataccgttta gtggagaggt tgtgaaaaag ctgtttagtt
     7321 tcgagtatta agaaaaattt tgtggaaatg gctttccaca tttttgcata aatttggctt
     7381 aataccgaga aactggcttt tgaacaccgt ttaaggaaga ggttgtgcgc ctgccgttca
     7441 gctccgagtc acaaggagta atttcaaaaa acagtttttc atgtttgatg actattgtga
     7501 cttgtgaccg aggagttggc cggagagcac cgtttattct aaaaaagaac tgcgaactct
     7561 cgcagttctt tttttaaaat acgggataaa ggaagtttcc agcagacaag agaagaaagc
     7621 aaaagaaatt gctatttgat tcacaaggtt ctataacgaa atcgcaatca atcaaacatt
     7681 tacaaagaag gtaattcaaa tggaaatctg atttgatgat gcttctgctg ttgaaataaa
     7741 gcagcatcta gcacctgaaa acaaactaat agtaacattc gaagatggag taggtccgta
     7801 ttttcagcat gcaataatcc atatgtaagt tcaattcacc cttgaaatca tcggaccaga
     7861 taaagttatg accaatctat cccaagcaat ctagaagaga tattagtaaa gggacattta
     7921 ctagaagtct tagatgagcc tataaatata tgttctgatg gcgtcatcag tggtctgatt
     7981 gacggaagct taggtgtgat cgatctctct ggaccaaaca acgaaggaat caaggggaat
     8041 ccggcacgtt aagaaaaaaa tagcataaaa aactagacac ttgatgagcg ttcattcaat
     8101 tgtttgaagg gactaggctg gtgtcatttt ttatacatat attttctctt tcgtcttgat
     8161 agggcttatg ggataatata aggaagaaaa tcatcgtttt attcaaaaag gagtttttga
     8221 caaatgaaaa aacgtatatt atttatcggt gatagcatta cagacgcagg aagagaccga
     8281 gcagaagcaa ctgatctagg taaaggttat ccacttttga ttgccggaaa actaatctcc
     8341 caatatccaa cgatggaatt tgaatgcatg aaccgtggga taggaggaga caaaattgca
     8401 gatctgcaag tacgctggca agaagattgt ttagctttac aacctgacta tgtatcgatt
     8461 ttgatcggaa tcaatgatac ctggcataat actagcgatc aggctatatt cggaactgag
     8521 aaatctgctc agcaatttga atccgtttat cgaaaattac taaatgaact tcaaacagtg
     8581 ggaatctgca acatcatctt gatggagccg tttgtacttc ctataaccga cgaccgtcat
     8641 ggctggcgta aagacttaga ccctaaaatc caaattgttc gtaaacttgc taaggaatat
     8701 ggcgcattgc tggttccttt agatggtata ttcaatgctt tagggattgt ttatggtttt
     8761 tcgaaatata caagagaaga tggggtccac ccaacgattg gcggacatga gatcattgca
     8821 caaagctgga tagatgcaat tgccgcagtc gattttttta gtggagataa aaatgagcga
     8881 aagaaaagtg agaaatgatg gaaatacggt gggcagtaaa agaagatcta cctcaaatca
     8941 atcagctgat tactgatcat ccagaatcat tcgtaaaagc aaaaacggca gctgacctaa
     9001 atgataagaa taaactattg ctcgttgctg taacaaaaga aaaacggatt atcggatttg
     9061 cgcaagcgga cgtgcaacag tcagaagaac gattggatca gcgaccatca ggaaaactaa
     9121 tccaacacac attagtaaca aaagaaaata cggaagaaat ccaaaaaaaa tttgcagaat
     9181 atttgatact ggaagctaaa aaaagaagaa taaaatcatt ttttgcccag ttttaatcaa
     9241 aaacagtaat agaaggagaa atacaatgag ttgtttagga aatgtcatct ggtttatatt
     9301 cggcggacta atcggtggtc ttagctggtt agcagcgggg atactttggt gtatcacgat
     9361 cataggtatc ccaatcggta tgcaatgttt taagatcgcc tccctttctt ttgcgccttt
     9421 tggcaaagaa gtaatttatc accagtctgg catgtcattg attgttaata tcatctggct
     9481 gatcgtttca ggcctaccaa ttgctctcgc acatgtcgtc agcggcatcc ttctatgtat
     9541 cacgatcata gggatacctt ttgccaagca atctttcaaa cttgctcgat tggcgttgat
     9601 gccattcggt gcagaaattg tataaaagag aataataaag gttagataaa gcatagagtc
     9661 aggtgggata catgtatttc acctgactct atgcgttctc ctgtataagt tcttccatgt
     9721 gacttttacg tcttttattt atatggggtt actgtttatg gaaagttgaa ataattttca
     9781 ttaaagaact ctttctatat ttttgaaagc gtagtggagc ttcgaatatc tgggaaggac
     9841 attttgcagg gattgaaaaa agatattgtc ctatcgaaaa attaatgaat ttagacaaat
     9901 tgccagcaac aggcttcaaa cttagttgct atcctgtcaa gatcaagaag gcaagtgcgg
     9961 gttggataag agcagtggca atgatcgaaa agaaaaagaa agaataagcc aaaacatctg
    10021 tatggaagaa attttccgat gcagatgttt ttcatttttt ctttcggata ccttgacata
    10081 tgaataaccg ttcatttata attagttatg aagagatatt catatgttga ggcgaggagg
    10141 tcattaaaat gaaaagttac agattagaag gtttagattg tgcgaactgt gcaatgaaaa
    10201 tcgaaaaagg agttcagaag atcaatggag tcaaggaagc aacggtaaac ttcacttctg
    10261 gaaaactaac gattgacgca gaggaagatc atttggctac gattgaacaa gaaataaaaa
    10321 aagtagtgaa ggaattagaa ccagatgtca aagtaacaga aatagataag gaaaaagtat
    10381 ctgaacatgg aaatgaaaaa gagagaaata cgctgttccg gattttattt tcccttgcag
    10441 gtatcgcttt attgctatta tttgatttta atgaaccaat tcgcttgata gggtatttat
    10501 tgatttatct gctgatagga tatgatgtag tgaagaaggc agtgatgaat atcgtcaaag
    10561 gaaaaatctt tgatgagaat tttcttatgt ctgttgctac gattggcgct atgttgatcg
    10621 gtgaatatcc agaagccgta gcagtgatgc tattttatca aatcggcgag tatttccaag
    10681 gattggcagt cagtcattca agaaaatcga ttcgcgaatt gatggcgatc cgtccagaaa
    10741 cagctcacgt gcagacgacg gaaggattga tgaccgtgaa ccctgaagac gtgcagatcg
    10801 gtcagtttgt acttgtgaag cctggtgaac gtgtaccgtt agatggaacg atcatcgaag
    10861 gagaatcatt agtcgatacg tcagcactta caggagaatc agtccctaaa tctgtatatg
    10921 ttggtgaaac agtattaagt ggatttatca ataaaaataa accattttta gttcaagtag
    10981 aaaaatctta tgaaaattct actatcagca aattattaga attagtagaa aatgccagca
    11041 gtaaaaaagc accagctgaa aatttcatta ctaaattcgc gcgctattac acaccagtcg
    11101 ttgtaggatt ggccgtttta ttagctgttt tacctccact tgttgtttct ggagcggcgt
    11161 tttctgaatg gatctatcga gcattgacat ttttagtgat ctcatgtcca tgtgcattag
    11221 tgatctccgt accccttagt ttctttggcg gtatcggagg agcaagtaaa atcggtgtat
    11281 tagtaaaagg ttcaaattac ttggagttgc ttgcacaaac tgagacagtg gtattcgata
    11341 aaaccggcac attaacgaaa ggtgactttt cgatccagac gatcgataca aaaatcgatc
    11401 caaagatatt catgcaatat gttgcgagtg cagaacagtt ttctacacat ccgattgctc
    11461 aatctgtttt agaaggctac gcaggtccgc ttttaccaac agctaatatc caagaatttg
    11521 caggtgaagg gatcttagct gaagttgatg gcaaacaagt attagcaggt aatcacaaat
    11581 tgatggaaag atttgaaatc tcttttcctt caagtcaaga aatcggtaca ttgctttatc
    11641 tagcgatcga tcaaagttac agtggttatc ttgttattgc agataccttg aaagaagatg
    11701 ccgtagacgc attggttcaa ttaaaaaagg ctggtgtgaa gaacacagtc atgttgacgg
    11761 gcgattcgaa aaaaattgct gatcatatcg ggaagcaagt aggcgtggac aagatatata
    11821 gcgaattgct tccagaagat aaagtgcagc ggttagagga aatcttacaa agaaacaata
    11881 aaaagaccgc atttgtcgga gatggaatca acgatgcacc ggtgctagca agagcagatg
    11941 taggaatcgc aatgggtgga ttgggaagcg atgctgcaat tgaagcagca gatgtagtca
    12001 tcatgaatga tcaaccatcg aagattgcag aagcaatcca tttagcaaag aaaacattga
    12061 aaatcgtcaa acagaacatt gtctttgcta ttgggataaa aattttggta cttgccttag
    12121 gtgcttttgg ttttgcatca atgggagatg cagtatttgc agatgttggg gtgacagtat
    12181 tagctgtttt gaatgccatg cgaagcttgc atgtaaaaaa taaacgttga tcaatgaaga
    12241 ggacgaatga acgtcctctt ttttttatat ccttttctta atgaaaaatg taaagaaaat
    12301 agataggatt ataaaataac taatgttttt aattttgcag aaaattcaaa atagcttgaa
    12361 attcaataag gtaaatgaaa taaaagaaaa taacttattt ttttgatgga aaaaatatga
    12421 aaaaacgatg tgtattaaat aaaagaatac acacataaaa taacactgtc ttgtaagttt
    12481 gttaaaaatt gaatatgatt acatctggat aacaaatttt tatcataaag gagagaacga
    12541 atgaacaaca aacaattacg ctggtttact gttgcgttaa ttgcatttaa catggtttgg
    12601 ggcatgggga atgtagttaa taactatgct cagcaaggag tatcagttgt cacctcttgg
    12661 ctattgattt tggccattta ttttattcca tacgcattga tcgttggaca attagggtca
    12721 gccttcaagg atagtaaagg aggcgtcagt tcatgggtcg aaaatacgac atctaataaa
    12781 cgactggcat actatgccgc ttggacttac tgggtcgtcc atattcctta tttggcacaa
    12841 aagcctcaag caatcctgat tgctggcggt tgggcagtcc aaggaaatgg aaatatcgta
    12901 aatacgatgt cagtacaaat ggtagcagtt atttcactta ttatatttct tgccttttta
    12961 tatttatcaa caaaaggact ttctactttg aaagtgattg gcggactggc cggaacagcg
    13021 atgttcgtca tgtcgatctt atttattctt ttagctgtaa cggcaccgtt catcaatcca
    13081 acgatggaat ttgccacacc acatatgaat caagtgaaaa catatattcc aacatttgat
    13141 ttcagttatt tcacaaccgt ttcgatgcta gtatttgcag ttggaggagc ggaaaaaata
    13201 tccccttatg tcaactctac aagaaatcct gcaaaggaat ttcctaaagg gatgatcttc
    13261 ttagcagcaa tggtagggat ttgtgctgta ttaggctcag tcgcaatggg tatgctgttt
    13321 gctagcgata atattcctaa agacttgatg gcaaatgggg catacagtgc ttttcaaatt
    13381 ttaggtaatt actatggtat cggtaactca ttgatgatca tttacgcatt gacaaacatg
    13441 attggacaaa tctccgcatt agccttttca attgatgcac cactaaaaat cttgttagca
    13501 gatgcggatc cagaatttgt accaaactgg ctacgtaaac gtaatcgtaa aggtacattg
    13561 gtgaatggtt atcttctgac aggtatacta gtaggaatca ttattttgtt gccgatcttt
    13621 ggtatcaaag atatgaatga attagtaaaa tggttgacga acttgaactc agttgtcatg
    13681 ccaatgcgtt acctatgggt gttcttggca tatatgatgt tgaataaagc ttataagaaa
    13741 ttcaattctg aatataaatt tgttaaaaat ccaaaaatcg gttttatctt tggtgcttgg
    13801 tgctttgcct tcactgcgtt tgcatgtatc ctaggaatgg tgccaaaagt agattatact
    13861 gctgatccta aagcatggtg gttccaatta ttcacgaata tcatcacacc aattgtcttg
    13921 atcttattag gtatgatctt gccagcaatt gctcgtcgag acaaaaacaa agaaatcact
    13981 gaaccagaaa cagtggttca gccttaaaat agaaatactt gttacaagag gttgtgacag
    14041 aagtggtcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    14101 aagtttcggc ttgtttttcg cagaagctac ttctggaaca ccgtgaatca gaggttgtga
    14161 aaaagctgtc ctgcatcaag taataagaac agccaaacaa aaatagcccc tcatattttt
    14221 cgttttgctg ggcttattac cgcagatgca agcttttgaa caccgtttaa gaaagaggta
    14281 gtgagcctgc cgtttaactc cgagtcacaa ggagcaattt caaaaaacaa cttctcatgt
    14341 ttgttgacta ttgtgccttg tgaccgaggt gttggcagga gaacaccgtt taaggaagag
    14401 gttgtaaaat cagcgatttg acctgagtat tagaggaaca aacgaaaaaa tagctcctca
    14461 tattttgccg ttttttgagt taatgctgaa ggtcagctga ttgaacacca tttattcgaa
    14521 acaagggact ttgacacgac ttttgtcaca gtcccttgtt tttttgcggc gttataagtg
    14581 gtatgatcga accaaattcc aaagagaagt gagggagaag aatgaagatc atcgtgattg
    14641 gacaaagtgg gtcgggaaaa tcgaccctcg caaggaagat caaagaaatc accgactttc
    14701 cgctactgcc gctagacctt ttatggcata caacagacta cagtattcag gcaaaaaagt
    14761 ggtttttgca agaacagcaa tcgtttatgg tatctaatcc gtcatggatt gttgaaggaa
    14821 attatacttc tacattagag gaaaggatta aagaagcaga taagatcatt tggcttaaag
    14881 tgccgcgtta tctcgccatc taccgagtag tttggcgttc tctaaaaaga aagataaaca
    14941 aaaaatctcg gccagatatg cctgaatcat tttcagagaa actaaacagg gaatacttag
    15001 aatttttatc ttttatctgg cattttgaag aaaacaatga accgaaaata cagcagctga
    15061 tccaagtagc taatgcaaga aataaactga tcatccttaa aacaagacga gagaaacaag
    15121 aatttttaac taaattgaaa atagagagca aaaataattg acagtttttg tttacaagcg
    15181 taatctgtat tcataagcta atgattacat ttgtaaacga aaggtgtgaa ataaatggaa
    15241 aaagtcaaaa cgccagtaaa gatcagtgat tcagagtggg agatcatgcg tgttatttgg
    15301 acacttggac agacgacagc ccaagaaatc acgcagatct tagctgattc gatggattgg
    15361 aaaccagcaa cgatcaaaac tttgctggga cgtttggtaa aaaaagaagt gatctggaca
    15421 gaacaagaag gaaaaaaatt catttatcat ccagctgtct cggagatgga aacagttcgc
    15481 agtgcgacgg aaaatctttt ttcccatatc tgtgcaaaaa ggattggaga gacgattgcg
    15541 gatctagtag aagaagccac tttgactcaa gaagatatca atgagatttt gaaacaactg
    15601 gaacaaaagc aaccagtaga tacgatcgaa tgtaactgta tcccaggtca atgtgaatgt
    15661 aaacaacatc aataggagga agaaaaaatg aaacaacaat tttcaatcga aggtatgagc
    15721 tgcaatcatt gtgcagcaag agtagaagaa acagtaagcg cacttgacgg cgtgcaaaaa
    15781 gtgaaagtaa atttgaaaaa agcaaacggt acggtcaagt ttgatgaaac aaaagttcaa
    15841 tccgaaaaga tttgtcaagc aatcaatgga ttgggttata aagcagaggt gatttgatgg
    15901 caacagcaga aaccaaaatg gatacgttcg tcattacagg tatgacttgt gcaaattgtt
    15961 ctgctaggat cgaaaaagag ctgaacggac aacctggtgt ggtcaatgcc acagtcaact
    16021 tggccactga aaaagcaagt gtcaaatatg aagggacgac cactgaaaaa ttaatccaaa
    16081 gcgtagaaaa catcggttat ggtgcaattt tgtacgatga agcccacaaa caaaaaattg
    16141 cagaagaaaa gcaagcgtat ttgaaaaaaa tgctattcga tcttatattg agtacggttt
    16201 tgactttgcc gttgatgttg tcaatgattg ctatgatgtt aggaagccat gcggcgattg
    16261 ttcacttttt tcattttcca atcgtccagt tagtgctgtc tgctcctgtc caattttatg
    16321 tcggtgctcg tttttataaa ggtgcgtacc atgcaatcaa gacgaaagca ccaaatatgg
    16381 atgtattggt agcaattgga acatcggctg cctttgcatt gagcatttac aacggatttt
    16441 tccgtggaca cccccaagat ctttattttg aaagcagcag tatgatcatc acgctgattt
    16501 tgctcggcaa atatttggaa catacagcaa aaacgaaaac aggtaatgca atcaaacaat
    16561 tgatgtctct tcaaacaaaa accgcccaag tgataagaaa cgggaaagaa gaaacgttag
    16621 cgattgaaga agtagtcgtt ggtgatcaac tagtcatccg tcctggtgag cagattccag
    16681 cagatggtcg aattatttca ggaagcagtg cgatagatga aagtatgctt actggtgaaa
    16741 atcttcctgt agaaaagaat ccggatgaca cgctttttgg cgggacaatc aatacgaatg
    16801 gtctgctaca catggaagtc acacaagtcg gcaagcagac agtattagcg caaatcattc
    16861 aaatggtgga agatgctcaa gggagcaaag ccccaatcca aaaaatcgca gatcggatct
    16921 cagggatttt tgttccgatc gtattagtca tcgcgtttat cacgctcata gctacaggtt
    16981 tgatcactgg tgattggcaa ctcgcattga tccatagtgt ctctgtatta gtcattgcgt
    17041 gtccatgtgc attaggttta gcgaccccaa cagctattat ggtaggaacg ggtgttggtg
    17101 cacgaaatgg aattttaatt aaaggcggag aagcattaga agcagctgct cacttagaca
    17161 gcattgtttt ggataaaact ggaacgatta cagaaggaaa gcccaaagtt acagatctag
    17221 tcggttcaaa agaagtccta tctatttttt atactttaga acaagcttct gaacatccac
    17281 taggtaaagc aatcgtggaa tacggaaaac tgcaagaagc agcaacatac gatatgattg
    17341 attttacagc ccacccaggt gctgggatca gcggtacgat taatggagta cgctattttg
    17401 cgggtacacg taaacgatta attgaattga acctatcatt tgatgaatac caagaacacg
    17461 cgttagaatt agaacagcag ggaaaaacag tcatgttttt agctgatgaa aagcaagtga
    17521 tcgggtggat tgccgtggct gatcaaatca aactagaagc caaacaagca atcaagcagc
    17581 tccagaataa aggattagat gtttttatgc tgacaggaga caacaaactg gcagccgaaa
    17641 cgattggtaa acaagttggt attgatccaa agcatatctt tgctgaagta cttccagagg
    17701 ataaagcagc ctacgtagaa aaacttcaga aagatggcaa aaaagtcggt atggcaggcg
    17761 atggaatcaa tgatgcaccg gccttagcat tagctgatgt cggtatggca atgggaagtg
    17821 gaacggacat tgcgatggaa acagccgatg tgacgctgat gaatagcagt ttggcatcca
    17881 ttgcacaaac aatcgagttg tctaggttga cattgagaaa aatcaaacaa aatcttttct
    17941 gggcttttgt ctataatacg attggtattc cttttgccgc actaggcttt ttgaatccaa
    18001 tcattgcagg aggagcgatg gcgtttagtt ccgtcagtgt attgttgaac tccctgagct
    18061 taaatcgaca catgaaaaag taagagaagg gttggagtaa aaatgaatgg gaacgatatg
    18121 gagaaaaaac atgagcataa aaaagaagta gtaaacaaag aaagtacaga atctcatgaa
    18181 aaacagatgg agatgaaaca tgaccatagt cagatggatc attccatgca catgggacat
    18241 aaccatggag atatagcaaa cagcaaacaa atggaccatt cgatgcacat ggatcacgaa
    18301 cacggcggca tggatcattc catgcacatg gggaatttca aacaaaaatt ttggctatcg
    18361 cttatcctag ctatcccaat cattcttttt tcaccaatga tgggaatgga atttccattt
    18421 caagtaacgt ttcctggttc tgattggctc gtattgatct tagcaactat actatttatc
    18481 tatggcggtc agccattttt aagtggagct aagatggaat tgaaacaaaa aagtcctgct
    18541 atgatgacac tgatcgcgat ggggattaca gttgcatata tttatagtgt ctattcgttt
    18601 atcgcaaatc tgctcaatcc acatacacac gtcatggatt tcttctggga attggctact
    18661 ttgatcgtta ttatgctact aggtcactgg attgaaatga atgctgtgtc gaatgccagc
    18721 aatgctttac aaaaactagc agaattactg ccagaatcag tgaaacgctt gacgaaagat
    18781 ggaaaagaag agacagtttc attgaaagaa gtaaacgaag gtgatcgttt gatcgtccgg
    18841 tctggtgata aaatgccaac agatggtgta atcttgaaag gtgaaacaat tgttgacgaa
    18901 tcagctgtga ctggcgaatc aagaggaatc aaaaaacaag ccaatgacaa agtgattggc
    18961 ggttctatca atggggatgg aacgatcgaa atcgaagtaa ctggaactgg tgaaaatggt
    19021 tatctagcga aggttatgga aatggtgcga aaagcacaag gagaaaaatc caagctagag
    19081 tcattatctg acaaagtggc aaaatggctg ttttatgtcg cattaattgt gggtatcctg
    19141 gcattcatcg cctggttgtt cttgacagat cttcctaatg cattagaacg tatggtaaca
    19201 gtctttatca tcgcctgtcc tcatgctcta ggtttagcta tcccattagt tgttgctcgc
    19261 tccacatcaa tagcagctaa aaacggatta cttttgaaaa accgcaatgc actggagcaa
    19321 gccaatgatc tagatgtgat catgctggac aaaacaggaa cactaacaga aggaaaattt
    19381 actgtaacgg gtgtcgaagt acttgatgat gcgttcaata aaaatgaaat ccttcaatat
    19441 ctaggagcct tggaagcgaa tgccaatcat ccattggctg ttggcattat gaattatttg
    19501 aaagaacatg aaatcaagcc ttatcaagct gaaaatctaa aaaatctttc aggagtcggg
    19561 ctagaggcaa cagtcaaaaa acaacaagtg aaaatagtta atgaaaaaga agttgagcgt
    19621 ctcggattaa acgtagaaca agcattattg aaaccttacc aagaacaagg aaataccatc
    19681 agcttcctga ttttagaaaa tcatctagct gcaatcgttg ctttaggtga cgtagtaaaa
    19741 acagaagcaa aagaatttat ccgaacattg aaagaaagaa aaatcactcc tgtcatgctt
    19801 actggtgaca ataaaaacgc tgcccaagca gtagcagatt atttagggat cgaagaatat
    19861 tatggcggtt tattaccaga tgataaagaa gctgttgtcc agaaatacct tgaccaaggg
    19921 aaaaaagtaa tcatggtggg tgatgggatc aatgatgcgc caagtttagc ccgtgcttca
    19981 atcgggatgg caatcggtgc agggacagat atcgcaatcg attctgcgga tgtcgtattg
    20041 acaaacagcg atccaaaaga tattttgcat tttcttgatc tagccaagca aacgcgaaag
    20101 aaaatgatcc agaacctctg gtggggggca ggttacaata ttcttgcaat tccgctagca
    20161 gccggaattc ttgcgccaat tggtatcata ttaagtccag cagttggtgc tgtcttgatg
    20221 tcgttaagta cggtagttgt agctctaaat gctttgacat tgaaaatcaa ataataatga
    20281 aaaaa
//
LOCUS       DAFEIE010000045        19413 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFEIE010000045
VERSION     DAFEIE010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.046"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            99..1025
                     /locus_tag="LP345_001891"
     CDS             99..1025
                     /locus_tag="LP345_001891"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBL1760670.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            1207..2100
                     /locus_tag="LP345_001892"
     CDS             1207..2100
                     /locus_tag="LP345_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBL1760671.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            2234..2359
                     /locus_tag="LP345_001893"
     CDS             2234..2359
                     /locus_tag="LP345_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1760672.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(2493..3125)
                     /locus_tag="LP345_001894"
     CDS             complement(2493..3125)
                     /locus_tag="LP345_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760673.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(3273..3815)
                     /locus_tag="LP345_001895"
     CDS             complement(3273..3815)
                     /locus_tag="LP345_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBL1760674.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            3950..4339
                     /locus_tag="LP345_001896"
     CDS             3950..4339
                     /locus_tag="LP345_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760675.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            4343..5107
                     /locus_tag="LP345_001897"
     CDS             4343..5107
                     /locus_tag="LP345_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1760676.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQAGEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            5236..6183
                     /locus_tag="LP345_001898"
     CDS             5236..6183
                     /locus_tag="LP345_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1760677.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            6313..7052
                     /locus_tag="LP345_001899"
                     /pseudo
     CDS             6313..7052
                     /locus_tag="LP345_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7343..8011)
                     /locus_tag="LP345_001900"
     CDS             complement(7343..8011)
                     /locus_tag="LP345_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1760678.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            8145..8432
                     /locus_tag="LP345_001901"
     CDS             8145..8432
                     /locus_tag="LP345_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760679.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8848..10386
                     /locus_tag="LP345_001902"
     CDS             8848..10386
                     /locus_tag="LP345_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBL1760680.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            10383..11348
                     /locus_tag="LP345_001903"
     CDS             10383..11348
                     /locus_tag="LP345_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760681.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            11335..12657
                     /locus_tag="LP345_001904"
     CDS             11335..12657
                     /locus_tag="LP345_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1760682.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKIPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      12720..12824
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            12898..13641
                     /locus_tag="LP345_001905"
     CDS             12898..13641
                     /locus_tag="LP345_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760683.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPIVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            13656..14648
                     /locus_tag="LP345_001906"
     CDS             13656..14648
                     /locus_tag="LP345_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1760684.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            14660..15397
                     /locus_tag="LP345_001907"
     CDS             14660..15397
                     /locus_tag="LP345_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760685.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            15387..16109
                     /locus_tag="LP345_001908"
     CDS             15387..16109
                     /locus_tag="LP345_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL1760686.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(16193..16816)
                     /locus_tag="LP345_001909"
     CDS             complement(16193..16816)
                     /locus_tag="LP345_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1760687.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            17211..17902
                     /locus_tag="LP345_001910"
                     /pseudo
     CDS             17211..17902
                     /locus_tag="LP345_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            18110..18400
                     /locus_tag="LP345_001911"
     CDS             18110..18400
                     /locus_tag="LP345_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760688.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         6678 a         3196 c         3913 g         5626 t
ORIGIN      
        1 atttaacgcg ataggtcgca tcggaaagaa gataagtatt gcttctttcc gtttttttgc
       61 tattattaaa taggagaaat cacaaaggag cgaatgacat gtcaaaaatt ttagtttttg
      121 gtcaccaaaa tccagataca gatgcaatcg gggcagccat tgcgttttca cacttgcaaa
      181 atgaattagg taaagaaaca gaagcagttg ctctaggtac acctaatgaa gaaacacaat
      241 acgcattaga ccactttcag ctatctgcac cacgagtagt agagtcagct aaagcagaaa
      301 atgcagatgt catgcttgtg gatcataatg aattccaaca aagtatttca gatatcagcg
      361 aagtaaatat tttagctgta gtagaccacc atcgtattgc aaactttgaa acagctaatc
      421 cattgtacta tcgtgcagaa ccagttggat gtacaagtac gattatttta aaactatata
      481 aagaaaacca agtaacaatt cctaaagaaa tcgcaggaat catgctctca gctatcattt
      541 cagatacatt gttgttcaaa tcaccaacat gtacgcctga agatgaagca gctgcaaaag
      601 aacttgcagc aatcgctgaa gtcgatctaa acacttatgg acttgaaatg ttgaaagcag
      661 gaacaaatct aagtgataaa tcagctgcgg ttcttcttga tttggatgca aaaagtttcc
      721 caatgggcag ttccaacgtt cgtatcgctc aagtcaatac agtggacctt aatgaagtga
      781 tggatcgaca agcagagcta gaagcagcaa tggaagatga aatgaaagca aatggctacg
      841 atctgttcgt attagttgtc acaaacatct tagacagtga ttcagaatta cttgttgctg
      901 gtaaaggaaa agaaaaagta gaagaagctt tccaaacaac tttgaccaac aaccgtgctt
      961 tgcttaaagg tgtcgtttca cgtaaaaaac aagtcgtacc tcaattgacg gctgtattta
     1021 gctaatcaaa tggtagtatg aagcattcaa aatgaatgga taagcgattg atataaaaag
     1081 aaacatagaa catactaaag gccgaagaaa tggaggagaa taacagtcaa ttatgactct
     1141 tgttcttcct cctttttacg taaaagcctt ttaagtaaaa taaaacggat agaaaagaga
     1201 acatatatga actattattc aaaaaataag gaaaactttt atcaaaaact gaccgatgat
     1261 ccgctttttt cttcattgac cgattatcta tatgaacatc gagaacaaga aacgattcta
     1321 agagaattga aaaaagaatt ttcgcaaaat aaattttccc attttcttga tttattgatc
     1381 gatgcaggat taatcaagag ggaagaacga agatatcatt tgaactttcc aatatttgat
     1441 cctaaagatt acttgcaaca agccacttcg gctgctgaaa ccatagctga acaattgaag
     1501 agactctctg ttgatgaaca aaaattagcg atgggagaag ttatttgggc gtattgtttc
     1561 gaagatgaac ggaaagaagc gtatttttat ggagtaagaa acagccgaga gacagaattg
     1621 ctgaggacaa ctgcaggaaa tgagaagtac cgttttatca cactttcctc tatagaacac
     1681 ttcccgctta ctttggctaa ttactttttt gtacagaaga atcagcttcc tgtaacgaag
     1741 gcattcaaag aattagccga acttattgga gacgtaaatg aatcgtactt ttttgatcaa
     1801 atagaagtta tcgttgacag gatacgtaag aataaatata aaaatcgccg gcctagtatt
     1861 ttccatcagt ctctacttgt gacgaatact ataaaggaag aagaatcatt cacattagaa
     1921 ttacctattg tcgaaaaaaa caattttgag attgaattac caacattgga tccttcattg
     1981 acaatggagg aaatggcctt tcttaaacga caaatctttt ctgagctgag caagaaattt
     2041 ataccgcatg cattttctta tatcaaagaa tatggaacag ttttagtgag taaaacctaa
     2101 gagagcagta agcaaaaatt atactgactc ttgcaggagg agcctttctc ttcctttatg
     2161 gttaaaagaa ttatttgagt attttgccta tctaccacct attagattca ctacatggtc
     2221 tggaaacaaa ggaatgcaaa aaaatggtga gaaatgtgga atgacaaagg aagtagtgat
     2281 aagaaaagtt agatttttaa ataatcaata ttatgattca gtcaagtatg gcattttatg
     2341 ggaagaacta gctgattaga ttaggaagtc catttgataa tccagaatca ctaagaaacg
     2401 aatggcgagt cattaataat ttatccaatc ttgggttatt cttttagatt gaagtgttta
     2461 aaactaaaaa agcatttatg aagtcgtaat agtcaggctt caaaatgctt tttattttgt
     2521 ttgttttttc tttgccacat aaatacacct agactgacga tgaagagcat atccaacaga
     2581 tttcctgcga cttggatcgt cgaagggttg gtcagtggca ttaaagcaag gacaaaaaag
     2641 gaaaacaagc tgtaaataaa acaggtgaca ggaactaatc gaaagaagag cggacatttc
     2701 aattggctaa aaatgagtga aaaaataaaa taagtaaaaa tggataaaat cacgactaaa
     2761 ccattcatga taaagaagaa aagcgtattg tgattaaacg aataaaaaag aattgctaaa
     2821 aaagaaaacg ttttaaatgc aatcaatacg cttgaagctt cgtttaacgt accaggatgt
     2881 cgatgaaaaa aataggcacc gaaataaaca gaaaacagta agccgcaaag agaagacaaa
     2941 atcaaaaaaa acggattttc ttcggcttct gtgatatcag aatgatccaa aagcaaccag
     3001 cctaatgcac tagaaggcgc atgtgaggtc ttaaggtatg aataacatag aaaaaataag
     3061 atcgtcaaag ttgcaaaaaa agagcctaaa tgtaaaaaat tagtggttct acgttgaatt
     3121 tccataatat ctccaaatta aattgataag tatataaagt ataataacaa attgatgagt
     3181 atatgtcgat gttttttaat caaaataata aataaaaact gtctaacatt taaaatttaa
     3241 tttagatatt agacagtttt taagtttgtg agttattttc cttgtcgttt tctcactttt
     3301 ttagtccaga aaccacctga aatatatttt ggctcataag aaatgataaa agcacgctct
     3361 tcgatttctt tgatcaggcg atacagttca cgttcgcttt ttctaggaga aagtatttcg
     3421 agaactagcc gctcaccttc cagccccatt gcagaagtct gtgtcacacc ataaccgtgt
     3481 tctctcagta tacccggcaa acttttatct tctgcgctat ttgctggcaa aatcgttgtg
     3541 accatgatgt atcctaatgc caatttgtct tcaatcaaaa ttccgacact gatacctact
     3601 gcgtaaccta acgcatagac aaataaattc agtggattat ctaaacgatc taaaacaagg
     3661 gataagccga cgatataaat cgtgatctcg accatactga caagtggagc aatcagtcga
     3721 tagcctttca ttgtcaacat gaaacgtaac gtgttcagag tgatataagc aaaattaatg
     3781 aggaagatca tccccaacat ttttggatca atcatttgta aaactccttt catttatata
     3841 acaacaatat caaaaaaaat cgtaagtgaa gaaaaattga aactttatac atacaaaaaa
     3901 atgataaaat gattataata gaattataaa gataggttag gtgattaaaa tgaaaacggt
     3961 caatcgtgtg ttttgtgcca gccacgtgct aagtctcctt ctcagtatat acttaggtgt
     4021 ctattcgatt caacagccaa ttgaggtaga gaacattgtt tttcagatgt cgctgacaga
     4081 tggtttaatt ttaagcgttt ttttcttttt gatactgttt attggtaata ttttcggtag
     4141 cgttgccagt tttttgaatt tttctattta tccactcctt tcgctagcat taggagtggt
     4201 gggactttgt tctctgtgct tatttcccga gccattcagt cctgcattta tattatttgg
     4261 tacactgaac ctgttccaga caactgttgg agcatggttg ctatggcgat caggaaattt
     4321 aatgaaaata ggtgagtaac aattgaatcc aattatattg aaacgttctg tccatcatat
     4381 tccagtgtta gaagttgttc tgaaagaatt aagagaggaa cgtattcccg ttgtcatcta
     4441 ttatcacgga tggcagacaa gtaaggagtt agttttgacg caaggaagaa aaattgcgca
     4501 gcagggcatt cgtgtgatcc tgccagatgc gatgaatcat ggggagcgca aacagccggt
     4561 ttcttctatt ccatcctata cattttggga tagtatctac ggaaatctgt ttgaatttga
     4621 cacacttatc aagcatttag aaaaaagagg tcttctacat gatcagcttg cagttggcgg
     4681 ggtttcgatg gggggaatga caacatgcgc cttgttggct aaacatcctc atatagtagc
     4741 gggcgtgtgt ttgatgggtt cccctgcacc tttggaatat ggaaaagaaa tcgtaaggcg
     4801 cgcatcggaa tataattatg tcgtaccaaa agactatttt gatttgattt catgggttaa
     4861 gagctatgat ttgtcattgc agccggaaaa gttagctgga cgtcctctgt tcttttggca
     4921 tggacaagct ggcgaaaaaa tcccttatat acaaacggaa cgatttgtag aaaaaaatcg
     4981 gcataagtct tacggaaaag aaattgtttt tcgttcctca aaaacacagc gacatatggt
     5041 acaaatacca ctaatggaag aagcttccac ttttttagca aaaaatttga taaaaaagta
     5101 taaataattg aaacggaaaa tcactcatga cgatagagga ttttccgttt tttattttgg
     5161 gctataataa actctgttag gaaaatttgg tataattgat agtaagaatg acaacatgtt
     5221 agaaaggaag agagcatgcc cactttagca gatgttgcaa aacgtgccaa tgtttcaaaa
     5281 atgacggtct ctcgagtcat caatcatccg gaacaggtga ctgacgaatt gaaagagtta
     5341 gttttctcag caatggctga actggattac cgtccaaata ttgctgcaaa agcacttgtc
     5401 acgaatcggt cgcagatcat caaattattt atactggaag aaatcgacac aactgagccc
     5461 tattacatga atttgctgat gggaatcgct aaacggatcg gtaaagcgca ttattctctc
     5521 caattagtta caaatgatgc cttcgacgtc ggttcttgtg atggatacat catcacaggt
     5581 gtcagaaaaa aagacttcga ttggatcgac cgtttggaaa aaccagttgt cttgtttggg
     5641 gaaaattctg aaggatatga ttatgtagac agcgataatg aatatggtac agcaaaagca
     5701 acgcaatatg ccttagaaag agattatcaa acgattattt atatcggtat cgaagtggac
     5761 gagccttttg aaatttcaag ggaaactggt tatttatctg tgatgaagga agttgatctt
     5821 cctagtaaaa tcttgcggtt tccaaatcat tcgacagaag tagaaagata tatgacagaa
     5881 aactgggcag attttacaga taaaacttgt tttgtatgta gttcagatcg gctagcacta
     5941 ggagcagtaa gagggattat aaatgctgga ggacacttgc ccgaagaatt tggtgtgatt
     6001 ggatttgatg gggtattttt agaccaaatc agttcaccta aattgacaac gatcaagcaa
     6061 gatattatac gtatgggtga agtatgtgga gaaatgttgt taaaaaaaat agaagaaaaa
     6121 ggggcgagtc aaggttatcg tcgttttttt cctgaactag ttatcagaga gacaacgaat
     6181 taagtcttat tactatatat atatttatga aattcatcgc tattttctta aaataatcag
     6241 cgcattgcta ctgaaaacaa tgaatctgtg ctattattga gaaaagttcc atttttgaga
     6301 aggatggttt gaatgaaaga aatcagacga aaacatttcc gttttcctgc gtacgatgat
     6361 gagttaggcg taaaattaac caacgacaag aagcgagtat tatttgacgg acaagaagat
     6421 cttttgactg aacagaatca gtccccgttt gaacagatga aagaatttca tttcacgaac
     6481 acgaacaccg agaaaatccg tcgcaagcgt cgtgcaacaa atggattgaa gtcagctccg
     6541 cgtaaggaaa atttggaaaa gcataaagga aaattaccgg attataccgg ccattaccaa
     6601 tcagaaatca catcgacagg acgaaaaaaa ctttttggtg attcctctcg ttctgtcaga
     6661 caaagtgaaa caaggacaga gtccaagcat actacacgaa acgcatctgt tgacacgaag
     6721 gtgcgggagc gttcttattt tgttcctaaa tatgtacccg catcgattat cccagaccct
     6781 agagaaagca aaatttctga ggatcattta atcgaatcga tgaaaaaaac ggatgactct
     6841 tatctgttgt tcgatacaga accgacgccg tatcaagaaa aaagaaatgg tgagccgtct
     6901 gtacgaacat tcaatcgaac aaaaacgtta gaggaaacaa agcagtcaga agaaaaaaat
     6961 cgaaaaaaag ccatggtatc ttagaacgct cattacaagg attgatcgat gatcaaggaa
     7021 actctttggg agaaaatagc tattttaaat aagtgatata caaatttata ttcggctaca
     7081 gttggaaagg aaacgctgcg gcgtttcctt attttatact ctatccgaaa gtttatatcg
     7141 tatcctcaaa tttttttgag tttaagcgaa ttttttctcc caataagtaa gaaaataatg
     7201 gcaaaataaa aaaacaaact attttcgcag atcgtttgca aaaatagttt atttttttat
     7261 aaagaagatt ttactgaata atatcatttt agtttacata atgatatttc tgtaaattaa
     7321 ataaagtagt gaaaaataag aatcagtgct ctaactgttc aagaggatca agtggttcaa
     7381 atgtttctgt agtctgtttt gcttccaatt ggggcaaaac agatccaatt tccagatact
     7441 tcactttatt caatgtataa gatagaatag aacagctaag taatgtatac agaaaatgtg
     7501 tgagatccaa ataaagcaag gagacaacta aaataccaaa agtaatcaag aaaagacttt
     7561 tgccaatctt aatatgaaaa tatttttcaa tggcttgata aatgatatct gttccgcctg
     7621 tgcttccgcc gaatcgaaag acgagaccgc aaccaatgcc agaaagaata cctgtcatca
     7681 aactattgat cagtagacta tctacagcaa aatgtatatg aaggctctcc cataaatgta
     7741 aaaagaaaac tagcgcaaat gttccgacga tcgtccggag aaaagcgtgt tttccaaaaa
     7801 gaaacaatga gataagcaat aaaggtaaat taaaaagcag tgaagtgaca gaaggagcga
     7861 atccaaaaag attatgcaaa agcaaagcaa taccagtaac cccaccatct gccagcttag
     7921 atggaatatt gattcctgtc acagctaatc cgtagattcc tgcgcctaaa atgattccgc
     7981 acaattctgt aaataaattt aattttttca tttctagcct cttttctttt gaaaattttc
     8041 agcaacttct ttattatact gacttatact cttacttcaa gaggaaaatg aaaaaaaatt
     8101 atttttggct gtttcttttt atttatcaaa taaggagtgg aaaaatgcga gcagcagact
     8161 tattgacaat tcttacaaaa tcacccaaaa aaacagagta tcaaggagtt tttttggctc
     8221 aagaacaaaa actggtgcct gtgacaatgg tccagataaa taaagcaaat caatttatct
     8281 ttttatttga acacggcaaa gcaccacttg ctatgaaaga catctttctt tttttgatga
     8341 agaaccgtga gaaagctgtt tattatcagt caaaagaaga actcattcct ctttatggag
     8401 tgaaagagat agaaaataaa gtggtgatat aagtaaaaat aagaaaacaa gacgtttatg
     8461 atgtcaaaac aaccattttt tacatttttg gcaaaaaagt gtcatgatac agtataatat
     8521 tcgttgaaca ggccaataaa ggtgttctcc cccacgagat ttctacttta ttggctgttt
     8581 ctttttatta aaataaaagt tgtgtgtgta aaaaagatat agctgattcc aagtgacaat
     8641 ttcgtataga tttttatggt attcgtagtg aaaaaacgag aaccaaaaag ttgatccgac
     8701 tttgttgctt ggattctttt tttgtcagca tatttagagg tatttttttc ttttttttgt
     8761 tcgtgctgta aggttaaggc aagacaagtt agttgggaaa aaggaaagaa atgtttatac
     8821 ttaaagaata acagaaagga aggtcgcatg aataatttta tacaaacatt aagtgaaaga
     8881 aaaggcgagt tgctggaagc tgcatttcaa catctgtcca tttctctcat ttctttgctg
     8941 attgcagcac tgattgctat tcctttagcg atttgggcag ccaatcataa aaaaatggca
     9001 gaagtcttat tgcagatcac gggtgtgctc caaacgattc cttcacttgc cttattaggt
     9061 ttacttatcc catttgtagg gatcggaact gttccagcat tgattgcact tgttatttac
     9121 gctttgcttc cgattttcca aaacacgtat attggtctag ctgaaattga cccgtctatt
     9181 gaagaagcag cggtagcatt tggtatgtcc agaatgagac gcttgctgaa agtagagctt
     9241 cccatcgcat tacctgtcat tatctcaggt atccgaactg ccttagtttt aatcatcggt
     9301 acggctactt tggcagcatt gatcggagca ggtggattag ggacatttat tttgttaggt
     9361 attgaccgaa atacacctgt tttgacattg attggtgcga tcagttctgc cttgcttgca
     9421 attatattca gcggactgat tcgctggttg cagcataaga aacctcgata ttccatcatt
     9481 actttagcag cagtggtgtg tttatttggc ggcgtttctt tatatcagtc tgccttgttt
     9541 aaaaatgaaa ccatcacgat tgctggaaaa ttaggagcgg aacctgaaat cctgatccaa
     9601 atgtataaag aattgattga agacaacaca aaaacagaag ttgaattaaa accgaatttt
     9661 ggcaagacga gttttttgtt caatgcactg gatcaaggtc aaatcgatat ctatcctgag
     9721 ttcacaggta ctgtcctaga aagcttggtg aaggtacctg aagcaatgaa aagtgctgat
     9781 ttgacaaaag aaaaaacata tgacgaagca gaagaattat tgaataagca attcgatatg
     9841 acattattaa aaccaatggc ttaccaaaat acgtatgcct tggcagtcaa gagatctttt
     9901 gcgaacgaac atcaacttaa aaagatttcc gatttggcag ctatctctga tcagatcaaa
     9961 gcgggattca cactggaatt tattgatcgt tcagatggat ataaaggaat ccaagaagca
    10021 tatggcttga atttttcaag tgtacaaagc atggagccaa gtttgcgtta ccaagcaatc
    10081 aataatggag atgtcaatat tgtggatgcc tattccacag atagccagct caaggagtac
    10141 gatctagtga ctctagaaga tgatcgaggg ttattcccag cttatcaagg cgcaccgctg
    10201 atgaaaaaag attttgctaa agaacatcct gaaatcgtta aagcactgaa taaattaagc
    10261 ggaaaaataa cagaggatca aatgattgat atgaattacc aagtcaatgt cgaaaagaaa
    10321 aagccgacag aagtagcacg aatcttcctg aaaaatgaag gattagtaaa ggaggaagat
    10381 cagtgactaa attaatcgag ttcaaacatg tgcaaaaaaa gtatgatgga aagtatgtca
    10441 tcgatgacct aaatctggca atcaaaaaag gagaaatctt tgttttggtt ggtccttccg
    10501 gtagtggaaa aacaactact ttgaaaatga tcaatggatt atctaaacca tcagcaggag
    10561 acatctactt caaaggaaaa tcgttaaatg aatataatct gcagaaaatg cggtggaata
    10621 tgggatatgt gctgcagcaa atcgctttgt tcccgaccat gacagtcaag caaaatattg
    10681 aagtcatccc tgaaatgtta ggttgggaaa agcagaaaag agcagaccgt gtagatgaac
    10741 ttcttcaaaa agttggctta tctcctgata tttatcgaga tcgtatgcct agagagttgt
    10801 ctggaggaga acagcaacgg atcgggatca tccgagctat tgctgcaagc ccagatgtga
    10861 ttttgatgga cgagccattt agcgcattag atccgatttc aagaaactca ttacaagaat
    10921 tggttttgtc cttacacgaa gaattgggca cgaccatcgt tttcgttacg cacaatatgg
    10981 aagaagcaat caagctaggt gatcgtattg catttatgaa ggatggagaa attatccaat
    11041 gtgacacacc agagcagtta ttgatgaatc ctaaaaacga ctacgttcgg catttctttg
    11101 atgaaccgaa acagacgaaa gagtggcgag tagaagattt agtcgtcaat ggatatttct
    11161 taaatgaaat accagaaaat gctcgtcaac aagtttgctt tgatacgcct atgaaagaag
    11221 tatattcgct tctttcggtg tatccaagca ttgtgatagt agaaaagcaa agaagtattg
    11281 ggtcgctgac aagtaaagaa atctttgctt ttttaagtcg agaggaggaa ggaaatgaaa
    11341 acatatgatg caatcatcat cggttcaggt gtgagcggct taagtgctgc ttatggattg
    11401 aaagaagcag gtaaaacagt actagtggtc gaagaagatc tatggggcgg gacttgtcct
    11461 aaccgtggat gtgatcctaa aaaagtcttg ttaagtgcag tagaggcacg taatcgggta
    11521 aaacaattga gtggaaaagg ttttaacgag atcccaactg ccaactggga agaacttcaa
    11581 aaattcaaac gaacatttac ggatccagtc ccagaaagcc gaaaaaaaca attagcagaa
    11641 gctgaaatcg atcatctttc aggaaccgct cgttttttgg atgattcatc tattgaagtc
    11701 aacgaagaag tcttccatgc ggattactta gttttggcaa ccgggcaaag acctacgatc
    11761 ttaccagtgg agggaaagga atacttgaaa actagtgcag actttttatc attgcctgta
    11821 ctgcctaaag aaatcatttt tatcggtggt ggttatattg cttttgagct agctacgatt
    11881 gccaatgctg cagggagcaa agtaaccatt gtccatcata atcaacggcc attaaaagaa
    11941 tttgaggcgt ctttggtaga ggaagccgtc catcaaatgg aagcatctgg cattcagttt
    12001 gcttttggtg ttgaaaccca aaagatcatt tcagaaggta ctcgctatcg tttagtcgga
    12061 aaagagacgg aattagtagc agatatgatt ttttgtgcga ctgggagaca gccgaataca
    12121 gaatctttag cacttgagca agcgaatatc gtctttgata aacacggaat tgcagtcaat
    12181 gattatctgc aaacgagcaa tccaaaaatt tttgcgtgtg gagatattgt ttcaaggaaa
    12241 atcccaaaat tgacaccagt cgccactttt gaaggaaatt atgtagctaa gcggataacg
    12301 gatgcaacaa gcgaacctat caaatatccg attataccta cgatcgtcta cgccagtcct
    12361 aaacttgctg aagtaggagt tacaaaaagt cacgcctctt cgtcagatca agtggtagag
    12421 atggatctta ccagttggtt cacctatcat cgtgtcaatg aaccagttgc taaggctgaa
    12481 ttgacctttg accagcaaaa ttatttgatt ggtgctgcag tgattagcga gcaagcagac
    12541 gaattgatcg atgatttgac actcgtcatc aatcaaaaat tgactaaaaa agagttggat
    12601 agctatatca tggggtatcc gacattggca agtgatctct cctatttatt gaaataatca
    12661 gcatgataac taaagcgctt gttgcttttt ccttcttgtg ctacacttta aaaaatgaat
    12721 acctgtttct ggggatgtcg tagacgacat gagagtaagt tgtgaactta gacccattga
    12781 acctgtcagt taatactggt gaagggagaa acatagcaga cgcttgaagc gggttactat
    12841 gtcgtgccca tttcaagcgt tttttgttat tcatattaga agaaaggagg taacaaaatg
    12901 aagaaaaatc tttatccagc agtcagtatg gcattcattt taattatttg gcagattgtt
    12961 gtcatagttt ggaaaatacc tgcctttatt ttacccggac ctgctgctgt attttctgca
    13021 ttagcggcag atgcacaagt attactttcc cattctgtca cgacattaaa tgaagcagtg
    13081 cttggtttgg taatagctag cgttctttct tttattactg ccttggcaat ggattattgg
    13141 aagtttttag aaatgtcttt ttatccgtta ctagtgattt cacaaatgtt gccaatcatg
    13201 gtgttagggc cattacttac cctatggttt ggtttcggta tgcttccaat agtgatcctt
    13261 gttgtcttga taagctattt tccgatcgta gtttcttttt cggatacatt gaggaaagta
    13321 tcaaaagagc aaatcatctt tttgaaaacg atgggggcag atacagggaa gatttatcga
    13381 atatataaaa taccagcggg tttatccggc ttcttttccg gtttaaaagt ggctgctact
    13441 tattgtgtca gcggagcagt cgttggagaa tggctaagcg ctcaagcagg cttagggtat
    13501 tacatgatac gcgtaaaaaa cagctaccag atcgataaag tttttgctgc gatcatttgt
    13561 gtcattctat tgagtttatt gctgaatggc gcttgttcat tattgaaaaa agggtattat
    13621 cgtatgcttt atatttttta agagaagggg atcaaatgaa aaaattatgg cttttattac
    13681 cgctactgtt gcttttatcc gcttgtggca ctgcaaaaga aacaagtagc aaacaagaaa
    13741 taaaggattt gaaaaaagtg acacttgttt tggattatgt accgaatact aatcatactg
    13801 gcatctacct agcaaaagaa aaaggctatt ataaagaggc tggtttaaat gtccaaatca
    13861 tcgaaccagg agataattcg acaagtattg gtctagtagg tgcggacaaa gcacaatttg
    13921 gtgtaagtta tcaagaagat gtcacttatg ctcacgcaga tggacagaat ataccagtca
    13981 aagcaattgc tacagtgatc aaacataata cttctggatt cgccacccta tcagacagta
    14041 acatccattc accaaaagat tttgaaggaa aaacatatgc aggttggcaa agtccaagtg
    14101 aagaagctgt cttaaaagct gtgatggaaa aagacggcgg ggacttttca aaactgacaa
    14161 tggtaggaag caatggagaa gggccagaaa gcttaggaaa atcctcagat atccaatggt
    14221 actttgaagg ttgggatatg atcaaagcaa aagaagcggg tattgaacta aactatatcc
    14281 cattgaaaga attagatgaa cggttagatt actatactcc ggtaattatt acgaatgatc
    14341 aactgatcaa aagtgatcca gaattggtac agtcttttat ggatgccacg aaaaaaggct
    14401 atcaggaagc tattaaggat ccaaatgaca gtgctaaact gttgcaaaaa tatgcaaaag
    14461 aaaatgatcg gacgttttta gaagaatcac aagcattctt gtcaaaaaat tatacggatg
    14521 atcctgagaa ttggggattg atggaagaaa aagtttggcg caattataca gcttttatgc
    14581 aggaaaacgg attgatcaag caagatgtac cttcgcaaga actattcact aatcagttta
    14641 taaaatagga gtgatagata tgtcaatcca aatcagccac ttgaatgtag tcattgaaaa
    14701 cctgaaaata ttagaagaca tccatttcac tatccctaaa gataccttta catcgattgt
    14761 cgcgccaagc ggagccggta agtcaacatt gctgaaaact ttaacaggag tccagcctat
    14821 gacttctgga acgatcaaag tagacgatca aaaagtaact ggtctccata cagcatttag
    14881 ttatatgccg caagaagata tgttacttcc ttggctgagc gtctatcaaa acgttacgtt
    14941 atatcaaaaa atcaatcatc taacaatcaa tgaagaacaa gtaagggatt atctggatat
    15001 ctttgggtta aacggctatg aacatttttt gccggaacaa ttatctggcg ggatgaagca
    15061 gcgaacggcc ttgttacgaa caatcatgaa tccttcttct tacttgcttc ttgatgaacc
    15121 atttggagcg ttagatgcta tgaccagagg gcagatgcaa gactggatgt tgaagctgcc
    15181 taaaaaagca aagcggacta ctttacttgt gacgcatgat atcgaagaag caatttattt
    15241 atcagacagg attcttgtgc tttccgcccg tccggcacat gtgattgctg agattcaagt
    15301 gcctgaaaaa cgacggtcac gtgaatggct actgcagcaa tcagagttga agcaaacgat
    15361 ttatcagtta ttggcaggtg aattagatgt taagtgatgc tcattgtcat ttagatggga
    15421 gtcagagttt agcactcctt cagcaggaac acacgatttt gacgatcatc aattgtgatt
    15481 cgccagaaga atggaaggaa aacagacagc ttgcagcaag taagactcaa gccttaagtt
    15541 acggtatcca tccttggaaa gcagatagct atacgtttga acaagttgag ccttttttga
    15601 aaaaagcaag gatcatcggt gaaatagggt tagataatat ttggacgaat gtaccgatga
    15661 ctacacaaaa aaaagtattt gagcgacagc ttgcttttgc agccataaat gagaaacctg
    15721 ttgtactgca cacaaaagga tgcgaaaaag agatcttaaa ttatatccaa gcttacccta
    15781 atcactattt gatccattgg tattcttctt tggactatca acaagactat attgatttag
    15841 gctgttattt cagcattggt cttgatttga aaaagaatcc agcagtctgg caactagcta
    15901 aagcagtccc aatcgaccac ttacttattg aaacggatgg actacatgca gcagagtggg
    15961 ctttaggggg gattttttca gaaaaagatt atgtctcact gcttgaagaa cagttaaaga
    16021 caatcgctga gatcaaagag ctatcagttg aagaagttaa aaaaaatact tatcaaaact
    16081 tggaacgttt cattagatta ggtaaataaa aaagagatgt gacacaacta gtgtcgcacc
    16141 tctttttggc tttctttgta taaaagtaaa ctgtttgatt aataaatgaa tcttagtacc
    16201 aaccgtttgc ttcccagaat gctttcgccg cttcccaaga accataacgt gaagtaacat
    16261 attgttctgc tactctttct tggtttgcag cagagtagtc accatttaag taagaagaat
    16321 ctaattggta acgtccgatg taacgtccgt tcgttgctgt gtaagaaccg cttgattctt
    16381 tttgtgcgat ccattctttt gcagagcttg tgcttgctgg agtagcagca gtttctgtta
    16441 cagcaggagc aggttgtgtt tcagcaacag gcgctgcttg tttttccgtt tgaaccgttt
    16501 cttgtacaac aggttgttca gcttggactg gtgcttcttg aacggctgct tgaggttcag
    16561 cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag taaatcaggt
    16621 taatatcaga aattgaattt gattctgcaa tggcattgat caaggagtta tcaccaacgt
    16681 atttttgaga aatcgttgat agagtatcac ctgattgaac ggtataagct tcgtccgcat
    16741 gagcagtcgt tcccatgaag aatgcagcgc cggcagccaa agttgttcca aaaagtaaag
    16801 ttttaagtga tgtcatgaaa aatctccttt attcgttaaa aagttttatt tgttgtgttc
    16861 aacgaggaat actttaacac gtgaaaatat ttcataggta aaagaagcat gacaatttat
    16921 gacaaatccg cgttttttgt aataaataca gtaatctatg aaatgaaaag ggttacgttt
    16981 aataaaactt gcttttttgt ttttgttcac cataaatatt tatttaagaa agtattaacc
    17041 tgcatttttc tctataaaaa agatttttta aatagataaa aaaggaggat taaatgagta
    17101 tttgatagta tttatattaa aattacatat gtaatttaaa aacgcttgac attgtgtttg
    17161 agatcactta cttttagcat gtaaaagtat tggattaagg agctatgcaa atgaaaaaga
    17221 aatttattac tggtgggatt gtcgttgcat ttctatgtct aattggctac acaggcacgc
    17281 ggtacgcaaa tgaaattatt ttgtggggtg gagagacaga tattgataca atcaatgaga
    17341 atctgacaca gcttgatcat acattgacag ataaagagca agcgattaca gatcttaccg
    17401 ctcgactagc acaaaaagaa cagacattgc aagattcaaa ggcagatgtc caagaatacc
    17461 aaacaaaagt aaatgaatta gaaaaccaaa aaaatcaatc ggcagcagaa aaacaaaact
    17521 tagaaagtca attagtcagc aaggatgcac aactacaaag caaacaaaat gaaatcaatg
    17581 tcaaactaga tgagatcaac caaaaaaatg atgaaatcaa tcatctgaat gcagattgga
    17641 cagcaagact acaagaagca caagcaaaac tttcagaatt acaaaatact gtaaatggtt
    17701 tgaatcaaca aatcgcaaca ctgacacaag aaaaaacaaa tgtagaaatc agttaacaga
    17761 tacacaaaag aaattagacg aagcaactgc tgaaaactca agcttgaaac aatatattca
    17821 aaagttagaa aaagcaaaag atgaagtgga agatacagct gataaatctc agcaaattgt
    17881 tgaagaacat ttgcgtaaat aatctttctt aacaagtaaa cctaaattag taaagaagca
    17941 acagtaatct atactgctgc ctcttttttt tagtacatgt ccttcatctt cgcaggaagt
    18001 gccaatatga ttttaagaaa ggtaatagac aaaaagtcaa aaagataaaa cagagtttct
    18061 tctttacaaa gggaatgtat gttcgtataa tggtattgag gtgaaggtta tggagaaaaa
    18121 atatggaaca gtagataaga tccgtacttt gcaagttagt gccagaccgt tgatccgttt
    18181 cagtttaaat ggggtcaatt gtttgattgc ttcccatagt ttgaacttcc tagctgaagt
    18241 agacgaaggg atgaagttag tcgttacagg ttattataat aatagaaagc aatttgttgt
    18301 gagatcctat catgtgttag ggaaacccaa aattgtggta gaatatgaga aaagtctata
    18361 cccaagaaaa aaggtccgac aagatgaaag aataaactag aaaacaagcg gctgagacaa
    18421 aaatgtccta gccgcttgtt ttggaaagat ggatgcagac gatgggattt gaacccacac
    18481 gagcatacgc tcacaagaac ctcaatctat atataactac atgtatttaa gtatttgtga
    18541 tgaatcacta aactttccaa actcatttga gggatattgc ttaaagattg aacagatcaa
    18601 ttcgaagccc tattagtatt cgctcaatgg ggggatcaga ggccataaaa agagactagt
    18661 cattactagt ctcaggtagt ggaattgtag gattttaaac gttcctggag agtaccggta
    18721 tgtaactcga agaggtgatt atcatagtcg taaaagtaaa ttgaagaagc ctcgcctttc
    18781 acacgagaac gtcctggttc gacagttaaa cctaacattt ggatttttga gacaaacgaa
    18841 tctatatctt gttcgtcaat tttaaaagca atatgattgt atgtctttgg cagtttattc
    18901 gacgaattct gcattactgc aatccatagg tccttaacta agaaaaattt ttctggatat
    18961 aatgaaaatt tttttgttga ctatcgtaga tttcttttgc atcaaataag gtatttaaca
    19021 attaagtatt taaaagataa cttttaagtt atctttaagt aatgcttaaa gctatgttat
    19081 actctattag gaaatataag aaggagtata aaaatgaaca aacataatag aaaaataacg
    19141 aataacaaag aactgatctt gttactaata gggatttggg gtatcttttt actctttaat
    19201 atgtatatgc cgactatgag agcggatgac gtagtttatg caagtagatt agatgaactt
    19261 ggctatttgg gtgcttcgat agaacattat aagacatgga gttcaagaat tattatagaa
    19321 ctattcttaa tgttcttttc taaacacttt atgctatgga aattattaaa ttctacgatt
    19381 atgttaggaa ttgtagtatt actttgcaag tat
//
LOCUS       DAFEIE010000046        19193 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFEIE010000046
VERSION     DAFEIE010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.047"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="LP345_001912"
     CDS             complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="LP345_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL1760689.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(1819..3042)
                     /locus_tag="LP345_001913"
     CDS             complement(1819..3042)
                     /locus_tag="LP345_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBL1760690.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(3073..3912)
                     /locus_tag="LP345_001914"
     CDS             complement(3073..3912)
                     /locus_tag="LP345_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL1760691.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(3929..4609)
                     /locus_tag="LP345_001915"
     CDS             complement(3929..4609)
                     /locus_tag="LP345_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760692.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(4611..5684)
                     /locus_tag="LP345_001916"
     CDS             complement(4611..5684)
                     /locus_tag="LP345_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1760693.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(5740..5978)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(6021..6254)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6331..7002)
                     /locus_tag="LP345_001917"
     CDS             complement(6331..7002)
                     /locus_tag="LP345_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1760694.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="LP345_001918"
     CDS             complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="LP345_001918"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBL1760695.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            10426..10863
                     /gene="ndk"
                     /locus_tag="LP345_001919"
     CDS             10426..10863
                     /gene="ndk"
                     /locus_tag="LP345_001919"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBL1760696.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(10885..11751)
                     /locus_tag="LP345_001920"
     CDS             complement(10885..11751)
                     /locus_tag="LP345_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1760697.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(11911..14004)
                     /locus_tag="LP345_001921"
     CDS             complement(11911..14004)
                     /locus_tag="LP345_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL1760698.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(14753..15376)
                     /locus_tag="LP345_001922"
     CDS             complement(14753..15376)
                     /locus_tag="LP345_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760699.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(15535..16932)
                     /locus_tag="LP345_001923"
     CDS             complement(15535..16932)
                     /locus_tag="LP345_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1760700.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(16964..17935)
                     /locus_tag="LP345_001924"
     CDS             complement(16964..17935)
                     /locus_tag="LP345_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1760701.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            18309..18734
                     /locus_tag="LP345_001925"
     CDS             18309..18734
                     /locus_tag="LP345_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760702.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT         5550 a         4068 c         3232 g         6343 t
ORIGIN      
        1 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
       61 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
      121 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
      181 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
      241 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
      301 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
      361 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
      421 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
      481 catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
      541 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
      601 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
      661 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
      721 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
      781 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
      841 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
      901 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
      961 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
     1021 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
     1081 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
     1141 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
     1201 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
     1261 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
     1321 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
     1381 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
     1441 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
     1501 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
     1561 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
     1621 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
     1681 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
     1741 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
     1801 acacaagttt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
     1861 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
     1921 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
     1981 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
     2041 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
     2101 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
     2161 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
     2221 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
     2281 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
     2341 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
     2401 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
     2461 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
     2521 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
     2581 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
     2641 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
     2701 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
     2761 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
     2821 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
     2881 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
     2941 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
     3001 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
     3061 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
     3121 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
     3181 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
     3241 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
     3301 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
     3361 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
     3421 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
     3481 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
     3541 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
     3601 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
     3661 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
     3721 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
     3781 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
     3841 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
     3901 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
     3961 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
     4021 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
     4081 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
     4141 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
     4201 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
     4261 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
     4321 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
     4381 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
     4441 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
     4501 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
     4561 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
     4621 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
     4681 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
     4741 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
     4801 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
     4861 atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc agaatgggca
     4921 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
     4981 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
     5041 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
     5101 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
     5161 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
     5221 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
     5281 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
     5341 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
     5401 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
     5461 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
     5521 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
     5581 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
     5641 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
     5701 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
     5761 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
     5821 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
     5881 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
     5941 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
     6001 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
     6061 tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt taacggtcga
     6121 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
     6181 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
     6241 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
     6301 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
     6361 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
     6421 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
     6481 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
     6541 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
     6601 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
     6661 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
     6721 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
     6781 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
     6841 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
     6901 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
     6961 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
     7021 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
     7081 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
     7141 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
     7201 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
     7261 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
     7321 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
     7381 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
     7441 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
     7501 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
     7561 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
     7621 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
     7681 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
     7741 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
     7801 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
     7861 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
     7921 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
     7981 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
     8041 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
     8101 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
     8161 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
     8221 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
     8281 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
     8341 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
     8401 ttcagcattt cttcaatcgc gccttttgtg atcatttgtg ttttaccagc tggatcagca
     8461 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
     8521 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
     8581 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
     8641 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
     8701 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
     8761 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
     8821 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
     8881 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
     8941 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
     9001 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
     9061 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
     9121 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
     9181 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
     9241 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
     9301 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
     9361 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
     9421 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
     9481 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
     9541 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
     9601 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
     9661 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
     9721 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
     9781 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
     9841 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
     9901 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
     9961 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    10021 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    10081 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    10141 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    10201 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    10261 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    10321 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    10381 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    10441 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    10501 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    10561 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    10621 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    10681 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    10741 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    10801 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    10861 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    10921 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    10981 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    11041 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    11101 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    11161 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    11221 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    11281 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    11341 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    11401 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    11461 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    11521 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    11581 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    11641 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    11701 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    11761 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    11821 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc attagaatgt
    11881 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    11941 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    12001 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    12061 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    12121 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    12181 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    12241 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    12301 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    12361 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    12421 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    12481 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    12541 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    12601 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    12661 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    12721 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    12781 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    12841 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    12901 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    12961 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    13021 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    13081 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    13141 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    13201 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    13261 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    13321 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    13381 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    13441 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    13501 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    13561 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    13621 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    13681 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    13741 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    13801 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    13861 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    13921 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    13981 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    14041 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    14101 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    14161 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    14221 ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag ctccttattt
    14281 cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc tgccaactcc
    14341 tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa ttgttccttg
    14401 tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca atcagctgac
    14461 cctcggtatt agattatgtc aggacgctaa ttttacaacc tcttggtaaa cggtgttcaa
    14521 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tataaggagc tattttttga
    14581 aattgctcct tgtggctcag agttaaacgg caggctcaag acctcttgat acacggtgtt
    14641 caatcagctg accttcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc
    14701 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctgtt tttcattgtc
    14761 cataggattg atattgtcct tgtgatgact cattcgtaat aattgaggct tgattttctt
    14821 cacttcccgt tatcgtttgt ccactgccag aatctgaagg acttgttcct gtcgactcgt
    14881 ttttttgaga agagacagtt gttttcttga cttgttcatt tgtctttttc cattccgcta
    14941 aacgatcggc gaccactttt ttgtctactt tttcagaata agcggtgatc acttttccat
    15001 ttttcaaacg ggctactttg tcgccatcat gagtcaaaag caaaacggtc aaatgcttgt
    15061 ctttaaattg atattgtctg agagaaatcg cactaagtac gtcatcgata ttaataaatt
    15121 gattttcttc ttttcctttt ggcaaataaa tgtccaattc gcctttttcg taattggcag
    15181 ttattttata ctccgcccac caataagttg agaattcttt tttgaaatta tctactgatt
    15241 ctttgcttgc tacgattttt tctgtttctt tctgagcaag atctgctgtc atttttcctg
    15301 aaaatgctgc ggataaaata agcagtaaga aaaaaccgaa taaccaaaag agaagaaacg
    15361 gtcttttttt cctcatgctt tcctccactc ctatttaatt ttgactattc tattatatac
    15421 aaaaaatgaa atagaaagac aaaaaagttg aaaaagatcg taaataattg aacttctttt
    15481 tcacaaaatg gtaagaatgg agaatttcac gcatttgctc tcaactattc tttcttaagc
    15541 ctcaaatccg tttttatctg atacgtcttt gaaccaatga cccgattttt tgattgttct
    15601 ttttccatct tgtgctaagt ctactgaaat aaagccatat cgattcttat atgcattggt
    15661 ccacgaccag ttatccatac atgtccacat atgatagcct aaacaattgg caccttcttg
    15721 aatggcttga tggacatatt tcagatgaga ttggacaaat tcgatccgat aatcatcgtg
    15781 gatcatgcca tcttctttga taaatcgtgc ttcgttttct acacccatac cgttttcaga
    15841 aataaagcag tcgatatttc cataatgatc tcgtacattg atcaaaatat catagattcc
    15901 ttgttcatag atctcccatc cgcgataagg attcatttta cgaccaggca tttcataatt
    15961 gtcgaaataa tcctcaggca ttggaccgtt tttagtatcg attggtgttt cttttgcttt
    16021 tacccggcgt ggctggtaat aattgatacc taaaagatct actgtatttt ctttgataac
    16081 cgtcaaatcc tctgcatgga tcacaggcat gagatcaagt tcttttacta tctcaatcaa
    16141 ttcacttgga aactcgcctt ttacagctgg atcaaggaat gaacgattga agaacgcatc
    16201 tgctatttgc gctgctttaa catcttcagg gtttgattcg tctcttggat agcttggtgt
    16261 cagattcaag atgataccaa taacaccacc ttgctccatt tcatggtaag atttgatggc
    16321 taacgctgaa gccaacgctt catgatagcc aacttggatc gcttttttca tatctgactc
    16381 ttctggataa tgccatcgat ataaataacc tgcttcgact ggaacgattg gttcattatg
    16441 agtaaaccat ttttttactt tcgaaccaaa caattcaaaa caacttttgg catatttttc
    16501 ataggcttca accgtttctc ggttcaacca tccgcctttt tcttgcagat acatcggcat
    16561 atcgaaatga tacagattca caaagggttc gataccgttt tcaatcaact catcaaaata
    16621 acgatgatag aaacgaacgg cttcttcgtt gattgttcca gattcatcag gtatcaaacg
    16681 gctccattgg atagatgttc gaaatgaatt atgcccagtc tgtttcatca actgtacatc
    16741 ctcttgatac ttcgtataaa cttgcgaggt tttttcaggt cctacttgat caaagaactt
    16801 ttgcggttct tttttgtacc aataatcaaa aatgttctct ccttttccat cgcctgaaat
    16861 ccttccttct gtttgtgggc cacttgctgc agaaccccac caaaaatttg ctggaaattg
    16921 atattttttc atcaaagcac ctctttttct tttttagttc gttttagttg attccatgta
    16981 tgatattttc catcacaatc actttttcat tttcttcctc ttcttttttg attcgtttta
    17041 acagctgttc tgctgctcgt tccccgattt tatctgttgg tggcgtgatc gtgattttcg
    17101 gaaggatact cagatcgttt ttatctaaat aatcatagtg actgaacgca atatccttcc
    17161 cgattctgac accttcttga ttgaaacatt cgatggcacc aatcgacata ttgtaattgc
    17221 tgacaaaaat agcagttgcc cctttttcta ataatgcttt tgccccgtaa tagccgcttt
    17281 ttctagaata gtctcctgta aagacctcta attggatcga tggatcattt tggaccgctt
    17341 ctttggctcc tgctaaacgt tctcttgcta cgtagtctgt ttgagtggca gcaataaatc
    17401 cgattttttt atgtccttgt tcaccatgat gagcgatcac ttttgctaca ctttctcgat
    17461 cattcactaa tattgtatca atacctgctg gtccttctgg acaattcaat gcgataactg
    17521 gaatactcat ttttgtgagc atttcaaatc cagaccactc ttcttcggat aagaagacaa
    17581 tcagcccatc gatcacatgc ttcatcaggt attcaatttt ttgttcaatt ttttctggct
    17641 gatcggcaaa cccgcttaat aataagctat acccattttc ttcagctact ctttcgatcc
    17701 ctgagacaac ttccgaccca aaacggctgg aaatcccgtt tatcaaaagt ccaatagaga
    17761 agcttcgatt attcttcaac cctttagcaa tgatgttttc tttatagtcc aacgctgaaa
    17821 tcgcttctgc tatttttttc atgttctttt ccttcagttg ctgaccattc aagtaacggg
    17881 aaactgttcc cactgaaaca ccagccatct tagccacatc acggatcgat gccatacatt
    17941 ctcactcctg ccagttacat ttgatttctc tttcttgttg ttcgattatg atgaccgcat
    18001 tctttgcata gtgttgcttg tcatcaatat ccatataact aaagtcttca gtagagcaac
    18061 ttcctctcac tattaattat acttaaacaa gtatttgaac cggttcattt ttaatatagc
    18121 atttttttaa aagattgcaa cactttttta aaacgctttc tgaaagtggc ggattttttg
    18181 cctttttaaa attttattct aaaatttact ctatttgtgg gtgttttgtg cgtttttctc
    18241 ttccatccgt ttgaagtttt acattccaat ggtataattt ctttatccta tcaaatgggg
    18301 gaagtatttt gaagaaatta atcgtactat ttattttgtc tgcgggactt ttgacattga
    18361 ctggctgtga tttgtttggc ggctctgacc aatcctcgga cgaaacaacc gattcttctg
    18421 tcttaaaagc ggaaaaagca gataccacca acagtgtata tacgctaaaa gtacgtaaag
    18481 atatggattt atccgcggga cagttgacat ttacagataa aaaaatggaa tggacacgca
    18541 cgtatcagac acaaggaact gattcttctg aatcatctga agaaaaaaca gtgctgacag
    18601 atatcaagat cactaccaaa gatgacgaat atattatttc aggaaaagaa aataaaaaag
    18661 aaacaacagt catatttaca aaaatcggta attaccgttt gaaggatgag gatggcaaca
    18721 tctacagtct atagtgccgt ctgttggatc ttcttttgtt tctccccttc ttttctgcta
    18781 tagtaaagaa gcaagatgat tgtaaaggag acgaaatgga tgatcgatag tcctgattat
    18841 tgtacatgta ataacaacaa aaatatccat acagaattta atgaccaagg aagcttgagc
    18901 atatgcgaca actgtcacaa actagtcaaa gattcattta aaacatttga atcttatcct
    18961 gttcaaaatt atgtaaaaag tagaagaaga taaacaaatc caagcaaaac tcactatggc
    19021 tgatttttat gaacttcaaa ctcagcttct tcctttgatc aagcttcatc agtaaaacaa
    19081 acagtggatc atttcagttt acaaatcaaa gagtaaagat ttatttattt caaatatttg
    19141 aatataaaat aaccaaacga tagaaaggct tattctacat cacgtagtaa ttt
//
LOCUS       DAFEIE010000047        18896 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFEIE010000047
VERSION     DAFEIE010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.048"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(21..251)
                     /locus_tag="LP345_001926"
     CDS             complement(21..251)
                     /locus_tag="LP345_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760703.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="LP345_001927"
     CDS             complement(687..1253)
                     /locus_tag="LP345_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1760704.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="LP345_001928"
     CDS             complement(1253..2209)
                     /locus_tag="LP345_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBL1760705.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="LP345_001929"
     CDS             complement(2209..2865)
                     /locus_tag="LP345_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL1760706.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="LP345_001930"
     CDS             3235..5253
                     /locus_tag="LP345_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1760707.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="LP345_001931"
     CDS             5680..8094
                     /locus_tag="LP345_001931"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBL1760708.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="LP345_001932"
     CDS             8442..9995
                     /locus_tag="LP345_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL1760709.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="LP345_001933"
     CDS             complement(10376..12160)
                     /locus_tag="LP345_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760710.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="LP345_001934"
     CDS             complement(12175..13896)
                     /locus_tag="LP345_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760711.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="LP345_001935"
     CDS             13996..14757
                     /locus_tag="LP345_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1760712.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="LP345_001936"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="LP345_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>18896
                     /locus_tag="LP345_001937"
     CDS             16664..>18896
                     /locus_tag="LP345_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760713.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6205 a         3353 c         3786 g         5552 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggtt
//
LOCUS       DAFEIE010000048        18362 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFEIE010000048
VERSION     DAFEIE010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.049"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="LP345_001938"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="LP345_001938"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBL1760714.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="LP345_001939"
     CDS             1011..2258
                     /locus_tag="LP345_001939"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBL1760715.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="LP345_001940"
     CDS             2334..2678
                     /locus_tag="LP345_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760716.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="LP345_001941"
     CDS             complement(2795..3121)
                     /locus_tag="LP345_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760717.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3494..4696)
                     /locus_tag="LP345_001942"
     CDS             complement(3494..4696)
                     /locus_tag="LP345_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1760718.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4813..5328
                     /locus_tag="LP345_001943"
     CDS             4813..5328
                     /locus_tag="LP345_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1760719.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5527..5973)
                     /locus_tag="LP345_001944"
     CDS             complement(5527..5973)
                     /locus_tag="LP345_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL1760720.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="LP345_001945"
     CDS             complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="LP345_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL1760721.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7852..8481)
                     /locus_tag="LP345_001946"
     CDS             complement(7852..8481)
                     /locus_tag="LP345_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL1760722.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8465..8929)
                     /locus_tag="LP345_001947"
     CDS             complement(8465..8929)
                     /locus_tag="LP345_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1760723.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9416..10684)
                     /locus_tag="LP345_001948"
     CDS             complement(9416..10684)
                     /locus_tag="LP345_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL1760724.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10915..11652)
                     /locus_tag="LP345_001949"
     CDS             complement(10915..11652)
                     /locus_tag="LP345_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1760725.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11719..12288)
                     /locus_tag="LP345_001950"
     CDS             complement(11719..12288)
                     /locus_tag="LP345_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL1760726.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12416..13288
                     /locus_tag="LP345_001951"
     CDS             12416..13288
                     /locus_tag="LP345_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1760727.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13630..14502
                     /locus_tag="LP345_001952"
     CDS             13630..14502
                     /locus_tag="LP345_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1760728.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14499..16457
                     /locus_tag="LP345_001953"
     CDS             14499..16457
                     /locus_tag="LP345_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1760729.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16708..17559)
                     /locus_tag="LP345_001954"
     CDS             complement(16708..17559)
                     /locus_tag="LP345_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1760730.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17682..18149
                     /locus_tag="LP345_001955"
     CDS             17682..18149
                     /locus_tag="LP345_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBL1760731.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
BASE COUNT         5559 a         3757 c         3383 g         5663 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgac cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
     3421 atatgagaag ctatttttgt ttggctgttc ttatgacttg atgcaggaca gctttttcac
     3481 aacctctgat ttcttattct tcttcatttg tagcaaaata attacggtga taaatgatac
     3541 aacatacact gataagaaca atggcacctg caaaataaaa cgcatagctt tcaccaatat
     3601 gttcaccaat cacacctgca ataaatggtg ctaaagctcc accgaaaaag cggacaaaac
     3661 tatagctgga cgaagcaacg tttcgttgca gacctggtat ttccatagca atcgtcgtca
     3721 acagtgtatt gataattcct tggaaaaatc ctgctaacac aatgctgatc ggtacaagga
     3781 ctggcataga agttccagct cctaataaca gcaaacaaat aatgaataag acaaatgctg
     3841 ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag
     3901 caatagccag aagcacaccc cagccaaaaa atacaaaacc gacttctaat tcagaatagc
     3961 caatcaataa aaatggcgca tacgcaagta aagtaaagaa tccgaaatta tataacaatg
     4021 cgattagtcc aactgaacga agtttatgat tgcttaacgc tttgacacct tcccaaaggc
     4081 ctacttttct ctttggtttc tcagtttcag gtaaaagtac cgctagggct ataaaaccgc
     4141 aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca tgaaccactg cccaagaccc
     4201 caccgactag agggccaaca gccattccgc agccaagtgc tgcttcatac atcatgattg
     4261 ctttttctgt gttaccaact aaaatactga cgatcgttgc taaagcagta gagacaaata
     4321 aagcattccc gacaccccag ccggcacgta acccaatcag cattccgata ttcccagata
     4381 atccgccaag accagcgaat acaacgatga taaacaatcc tgtcatcaat gtttttttca
     4441 aaccgatccg actagataag aaacctgtaa atagcatcac cacaccagtg actaacatgt
     4501 aactagtaaa taacagggtc gtttcagctg gcgtagcgtt taactgtgca gcaatcgttt
     4561 ttaagattgg gtctactaga cccactccca taaaagcgat catacaggta gctgctacaa
     4621 ctagcgctga acttttcccc tttgtttctt catttgtttg ttcttgtata tctatttgat
     4681 tctccaatat ttccatccct ttctctctat tagcatcata catgatttat tttacatgta
     4741 aatatgcaca tgtaaaacgt ggaaacttta ctgtgatata ataaagaaaa taagacgaga
     4801 ggtaggattt ttatgaatac tttagcctat atattattat gcgtgctttt atccaaacca
     4861 cgttctgggt atgaattgaa gcagctgatc acaatttttt gggaagccca tcacagtcag
     4921 atctatacaa cgcttgccaa gttagaccag cagggttatg tgaccgtttt ggacaaagac
     4981 gagcactctc aaaaaaagat ctaccacttg actgatgaag gacgtgctct tgtagaggaa
     5041 tggatcaaag aggaaactcc cgctcctacg caaaaagatg aatttctagc aaaaatctat
     5101 gctttttcga cgctcgataa aacaacagct actggactgc tattcactag agaacaacag
     5161 ctgaacaaaa tcatgcaaaa aaatcaaaaa aaattgaatg acctctcgct agacaagaaa
     5221 caagaatttg gacgttatgt tgtgatccag cgcagaatta tgctttgtca gcaggaactc
     5281 caatggtgtc agcaagtaag agaacaaatg cagcagtttt ttgagtaagg gataaacaga
     5341 acctttctag aaatatctat tgaagagcaa attatcttca ataaaagagc aatacagttg
     5401 gaaaagaaaa agcgatccga acgacaggcc aaaacctatc gttcggatca ctatttttct
     5461 agaactgcat tcaagagact atgacaaaaa gcatgccaag gccttttttc aaataacagt
     5521 gttccatcat tcattacttt gaattgcttt tagcacactt cttgaaagcg ggccaacgat
     5581 gatcaactgc aacggtaaag cggcaatcac attcattttc caagcattca tataagcaga
     5641 gaataattga tcaggtattc cttgttccat gatcacaccg aataaagaca tacatgtcac
     5701 cattcctaaa accatcaagc atgaaatagt taagatcatt tggaccttgc tttctggatt
     5761 tactggtagt ttaaaggcaa tttttttcgc cagcacaccg atgatgaaga catccaaaat
     5821 gaaagccacc acgaatccag gcactagacc aatcaacaaa cttgataaat gaagatcttg
     5881 atgcagccat aaattatacg cgctcatccc caagaccatc aaaaaacaca tcattgttgt
     5941 aaaaattatt ccttcttttt tatttgtagg caatctgtac cactccttta aatttgtcac
     6001 gaaaatcatc gtagcacatt taaaaatttc tcgtaagtac tttttttatt ttctgccctt
     6061 ttatttcata aacttcatca gccgtacgct cgacaaagta agaatcatga gaagtaaaca
     6121 aaatcgttcc cggatatatt tgcattagct tctctaaagc ttcgatcgtt gccatatcaa
     6181 taaaattagt cggttcatct aacagcaaca cattacttgg cttagtaaaa agcaaagcaa
     6241 tcgtcagacg ggtcgcttct cccccactta atgtacataa cggtttcgtc aaagtttcct
     6301 gagcaaaccc taagtgattc agcaaactac ggacaagcga ttctgaaaac tctgtttgtc
     6361 tcatgacaaa acgaatgatg gattcttcag atgtcatttg ataacccttt tgctgatata
     6421 cttgaaagct tactttcgga gagagaagga ttccttctcc ttgtttgcgg atatgttcta
     6481 ataaggttgt cttacctgaa ccattttcac cgacaatcgc gattttttta cctaaagaaa
     6541 actgaaaatc accatttacc agtaatgttc tcccacttct ttccaattgg acattttgtc
     6601 ccatgatggg atagcggctg tggagttcaa gagattttgg tactggaaaa cggatttgtt
     6661 tcatctgctg cggcttggtt gtttctccta ttttttggag tcttctctct aatgttttcg
     6721 cattcttttg gatggctttt tgtacactgt ctttttgttt agaggaagac aaccgatccg
     6781 gtctgatttg ttgctttttc tttttactgg acactttttc caacttttcc gcttgttttt
     6841 tcttttcttg gatcgatttt tccaatcgtt ttttctcttt catgatcgac tctgcttctc
     6901 gtagctgagt ctttttctcc aattcctttt gagtgagata ggcactataa ttccccgaaa
     6961 actctcggat ttctccgtct tttacttccc agattttcga tgctagctca tctagaaaat
     7021 agcgatcatg actaacaaaa accagcgtac cataataata acgaagctct tcaatcagtc
     7081 gatcaatact ttttctatct agatgggttg ttggctcgtc tagaagcatc ccttgttcat
     7141 aagaagaaag aagacgtatc aactcgatct ttcgttcttc ccctccgctc catttccgct
     7201 ctgaagtttc ttccagtctt aactggaaat gactggctaa ttccaaattt aggtcctttg
     7261 cttcagcgag ataggttaat tgaggcaggt agttgaaggt gatctctgtt tggattttcc
     7321 catgatcggg aaaaagttca ccggctatta gtttgagcaa agtcgattta ccgacaccat
     7381 tttctcctat gatccctata cgatcttgct gatagacacg aagagaatca atagatagtt
     7441 ctagctggtt gccaaagctg acttgtagat ttgttatatt tactgctaaa ttttccatat
     7501 gttttacact cctatttcat gtaaaacaac aattatcgat actaaaaaag agcagaaaaa
     7561 tctgtttgca aaaaaactgc atcacatctt ttcctactct gaacgaaata actatgacta
     7621 aatcaccaaa tctgtcatag ctttcaccta ttctactgtc gttcgaaaaa atggacatac
     7681 tccatccatg aaattgttgt ttatacatgt cttttgaatt tatttagttg ttattcaaaa
     7741 gttcgaaacg taatttcatc gatgcagtca tttttccgac ctcctttttt attaggttac
     7801 cacacacgat tcaaaaaaag caatagctac tgaatagtaa ctgaaaacct tttattcgaa
     7861 cgtagtgatc ttttctggtg ctaaacgaac agactcgtaa ccttcttcta ccgcttttcc
     7921 tattgataaa ataataactg gaacataacg gtctttatcc aaaccaaatg cctctgccaa
     7981 ctgatctgct tcgaatccac caattggatt tgtttcatag ccatgatcac gcgcaactaa
     8041 catgaattgc atagccgcta agctagaatc gactttgact acatcgttca tttcttctct
     8101 tgaaaaactc ttgtaataag gaatgatcgc agctaattgt tgatctctga cttcttttgg
     8161 catcttccct gattcgtaag cttggttata gatttcttcg ccatattcgt aacattgcat
     8221 atcgccaaaa atcatgacca ttgcagaaga agtatcattt tgtctcgtat tgaaacggat
     8281 caaaggacgc aagatttctt ttgcttcctc gctttcagcg accacaaagc gccatggttg
     8341 catattgaca gaagaaggtg cagtcgtcgc ttctttgatc atttccagca tttcttcgtg
     8401 tgggattttg tatgtttcat catatacgcg aacggatctt ctaccagtca taattgttga
     8461 aaaatcattt ttttgttcca ttattattaa cctctttcgt ttctgttgtt atattgcaaa
     8521 gttgggtatt caatttatct aaaagtgtta gaaattgttt catttctaca tcgctgaaag
     8581 ccggggatag cacggaacct gtatctttat ggtccatttc acaatgctcg attttcttct
     8641 gggctttttc tgttagcgct acatacactt cccggttgtt ctgaggattt ctctgacgcg
     8701 aaacatagcc atttgcttcc aataccttca gatgacgagt aactgctcct tgatcaatct
     8761 gcaacttttc ttgcaaactg ctttgtagca atggattttc ttctttcagt ctcatcatga
     8821 tctcgtatct agtaagactt ataccgatat tttcttcaaa gatctggacg attttttgat
     8881 cggctaattt gatttgatat aaaaggtgac taatctcttc taaagacata atttcctcct
     8941 ttctaataat tgactcgtca acgattgact tgtcaataat agaataaaaa aagaaaaaag
     9001 tcaaagaatc agctgtgtaa taaaaaaaac gctctcaata gaaaagtata gagaaaagaa
     9061 attttttgta gaatgaacgg aaaaaatgat aaagaaagca caacgctaaa accaagatta
     9121 ttgattctta tcaaactata gaagatagct cttctgcagt agaaaatttt acaccgccaa
     9181 aaatttccga aatcgccttt tgcaagaatc ccgtcgaata ttagaaattg gatcagtatg
     9241 cttaaacagt aataaaaaag ttatgacaag atgttgtcac aacctttttt gagtaaacgg
     9301 tgttcaaaaa cttgcatctg cggtaataag ttcaaccaaa caaaaaacat gaaaatctgt
     9361 ttttgtttgg ctgttcttac tacttgatgc agggcagctt tttcactacc tctttttaat
     9421 aaccataaaa tcctattcct tcatatctcc agcccatcgg tgttagccaa tctctttcct
     9481 tagcactcaa ggtatagtga tgggtaccag ttttttcatt tggattaaat agtcgataaa
     9541 ttggcttgga accaccagaa taaaaactta gaccttcata acgccaaccg atttttgtta
     9601 aagagttgat ctcagattgt gccattgtgt aatgatggtc tccactgtaa ggattgtata
     9661 aacggtagac aggttgtccg ctgtttggtg cttgccaagc aatcccttca tattcccagc
     9721 ctacagttgg cagataattt ttttctccgg cattcaatgt atataaatgt tctcctgtat
     9781 gacggttata cagacgatac atcggagaag ttgaagttgg tgctgtatca tactgtgtca
     9841 gattataggt ttcgattaca ttgttcaatg tagaaccata attaggcgca gtggcataac
     9901 gacctgttag ccaagccgta gcatctttgt aagagttcgt attgcttttc catgcaccgg
     9961 aatagtagta aacgcctggc tgaaaagaag tcgtcttcaa taccgttacg ttatcttgca
    10021 atgattcttt gtacgaagga tattttctaa aagcggcatt caccgtaatc cattgcccat
    10081 tcacatattc cgaagtaggc atcgtaacag attggccatt atagcttcct ttaatcccaa
    10141 atagattgta attaggggca gaagccaaag tactgttccc ccagccactt tcaacgatgg
    10201 cttgagcaat catgactgat gcatataagt cattggcact tgccaaactt tgtgcagttg
    10261 aggcaatact atcaatgaac gcttgttgag aattagcaga tgagcgagca taaaaagcat
    10321 agccagtata gttttcgaat tcagacaaat ctgcttgatg ggtatgtgtc aatgtttgcc
    10381 catctgtcaa ttggttcgtg atttcttctg cattctctgg attgttctga gcttctgctg
    10441 atgtactgtc ttcggtttgt gtttgttctg ttgtttcagt tgttggttct tcggttgaaa
    10501 ttgtattttc tgagacagta gctgactgca aagtactctc tgtatcgttt tcaattcctg
    10561 tttctgaaga actcgatgtc tgagttgcga cagtttctgt cgattcttca gctagcactg
    10621 ttgtgttggc aactgctaga tttcctaaaa gaataacgct aaataataaa ttctttgctt
    10681 tcatcttttt tctcctttga attatgaaac ttttcctaaa taacagtgta actaaaaaag
    10741 taaaagcaag tcaatgtcca tatttaaata acatttgttt ctttttgatg aatttgcttt
    10801 ttctacataa aaagacgtaa atgaagaata ttcttctcca ttcacgcctt aaattgatgg
    10861 tcgtttgaat aactatttaa caagtaattc tctttggata ttatccgtta tggattatac
    10921 ttcctgtgtc gtcggacgga taatcatgtt actgacagac atccggtctg gcgtttctat
    10981 cgcaaatgct acagcagaag ctatatcttc ggaggtcaat ccccattctt tttgcgcttc
    11041 atgaagttca agagcagcct ttttgtcgct gatggtttga tataattcag tttgaacagc
    11101 tcctggagag atgatcgtag atttgatgtt attttgccgt tgctcttgac gtaatccttc
    11161 catgattgca cggacagcaa attttgttcc gcaataaacg gcggaatcag gataaacaac
    11221 atgtcccgcc acagaatcag ttgaaatgat atgcccagat ttttgttttt ccatgattgg
    11281 aagtacggcg gaaattccat ttaacacacc catgatgttg atatcaagca tattttgcca
    11341 ttcatcacgg tgaccttcaa ctaatggagc ggttggcatg attcctgcat tattgtacaa
    11401 tacatcgatt cgaccgaact tttccatcgc taaatcgata actgcttgga cttgtgcaaa
    11461 atctcttaca tctgctgttt gaatatatag ctcagcttct ggtaaagatt cttttattgc
    11521 ttttaggcga tcttctcggc gtgcagctat aactagttta gccccttttt ctgctaatag
    11581 cttcgttgtt gcttcaccga ttccgcttga agcgcccatg atgacaatca ctttttctga
    11641 taaatcattc attctattct cctcctgttt tgaaaaatct cttgcttata ctcactatct
    11701 cttatttcat cttactgttc aaataatccg ttcgacaggt ttgacgattt tggcagggat
    11761 tcctgcaacg atggtattgt ctgggacatc tttcgtaaca gttgcattcg ctgcaacaat
    11821 ggcattctcg ccaatcgtta cgcctggcag aatagttgct cctgctccga tccaagcatt
    11881 tttcttgatg tggattggct ttactgacaa gcctcttcgt tcttttggat cggttagatg
    11941 gttcaccgtg atgaggttga cacgaggacc aatcaatact gaatcttcta aacagatgcc
    12001 acctaagtca acgaacatca cttgacgatt gataaagaca tttttcccta tactaatatg
    12061 tttgccgaaa tctgtataaa aaggcagcag aacagtcacc gtatcatcta ctttgtcact
    12121 aatgatattt tctagccgtt tgcggatatc tgctggttca tggtacccag tattcagcgc
    12181 tgctaaaggc tcttcgtttt cagcttggat ctgatggatc acttcaaaga gcggatccgt
    12241 tactcgaatc tctttattga cgatttgttt ttcgatgagg cttgtcattt tgctccctcc
    12301 ttttatcctt actttataac ggacggctta tcatgtctaa tacttataaa acatacttaa
    12361 ctattccttt taactatact tagtggtatg cttttttaaa aacaggaggg aaaaaatgga
    12421 tattcgtata ctgacgtatt ttttagcagt agctagagaa aaaaatatca gccgagcagc
    12481 aaaatctctg catatcacgc aacctactct ctcaaaacaa ctgaaagatt tagaagaaga
    12541 acttggtgtg acacttttca ctcggggctc ccgagagata cagttgacgg attctggtcg
    12601 atatctttat tcaaaaggaa aagaaatctt gtcgttggta gaaaaaacgg cgaacaattt
    12661 aacaaatgac gcaatcatct ctggagaaat ctacattggc ggaggcgaaa ctaaagcaat
    12721 ctctttcatt tctgatagcc ttcattcgtt gatcaaggcg catcctgata tccagtttca
    12781 tttatatagc gggaatgcag atgatatcat agacaaactg gatagcggat tacttgattt
    12841 tggactcgta atcgaaccga caaacaaaca aaaataccag tcatttcgac tgccagccca
    12901 agatcgttgg ggacttttga tacatcgaaa tcatccttta gcaaagcaaa ccgtcatcca
    12961 tccgcaggaa ctgaaaactg ttcctttgat catttcccgg caaacgtcag tggacagtca
    13021 actagctgaa tggctaggtt tcagcataga tcagttatcg atcgtcggaa catataactt
    13081 attgtacaat gcttctttga tggtcgataa cgggactttt ggtgcattag ctctagatgg
    13141 gatcatcaat acttatggga cggaaaaaat attcatccca ctcgatccgc cattacaagc
    13201 ttcactgaat ctcatttgga aaaaagacca gcctctttct cctgctgctc gtaaattttt
    13261 agatgtccta acggagaaat acagttaagt agagtttttt tccttcgctt tcagcttttt
    13321 aacaacgaat aagataagca aaagatccaa cgattaaata acataagttt cttaatttat
    13381 ttcttccttt tatttctgat aattccagta aattactata attataaaaa aagaattgac
    13441 aaaacataac tgtctatata aaattgatta cgttaacaat aattcgtttc atgtgactag
    13501 atcatactag gcatgaaaaa tctctgagga acatggtttc cctaggaggt ttttcgtgtc
    13561 tatttttgtt tggccgcaat caactggtct agcaaacgtg aaaaccaaat cttcaaaaag
    13621 ggtgcgcgca tgaaaatcaa aaagatcttt aatcaaaatg cagtattggt agatgacggt
    13681 ggacaggaaa aagtagctat tggaaaaggg attggatttg acagaaaaag aaatgatttg
    13741 atttttgatc gtgatgtcga acggatattt gtcatggaac cagaaggtca aatcaagttg
    13801 caaaatttac ttaatcagat tgatgaacgc tttttatttg cagcagaaac gatcattgat
    13861 catgcggaaa ctgttttgat ggaaaagttg aatgaacatg tattgatcgc tttgaccgac
    13921 cacattgctt tttctgcgga gaacattaat aacggtatcg tcatccgcaa caaactttta
    13981 agagaaatcg aagtgcttta cagtgatgaa ttcagtattg ctcaatgggc agtagagtat
    14041 ctgacaaaag agcttgggat tccatatact tatgacgaag caggatatat cgcaatccat
    14101 attcacagcg gacgaagcgg tcggaacaat aaccatcgca gtatccgtga agtgacgatt
    14161 gtatctgaca tcatccattt agtggaatca gaattggaaa cagatatcca ttcagaacca
    14221 ttttcactga attattcaag actggtgaat catttacgac tacttctaca acgaacccat
    14281 gcgcaacaat atgctgtttt agacacggaa atcgtagaaa tggtcaaacg aaaataccca
    14341 gaaagctata agatttctaa aaaaatccgt gtgttgctga ccaaagaata ccagctcgcg
    14401 atcacgaaag aagaactggg ttacttggcc atccatatcg agcgtttaag aagcgcaatc
    14461 gtacaaacaa atgttaacaa tcatgaggag gaaaaaaatt gaaagcatat ctacaacgaa
    14521 tgggacgttc ccttcaactt ccagttgcgg tcttacctgc tgctgcttta ctagtaggga
    14581 tcggaaactg gtgggcatct tatagtaacg acattgtcgc tcatttttta caagctggcg
    14641 gtaacgcagt tttaggtcaa ttacctttgc tgtttgccgt tgggttagca ctagggatgt
    14701 cagtggacaa atcaggtgct gctgccttgg caggtttggt cgcatttgaa gttccagtaa
    14761 atgttttaaa aactgattca gtagctactt tattgaatat caaaccagaa tcagttgatc
    14821 catcttttgc tcagatcagt aacgtattta ttggtattat tgccggattg attgcggcag
    14881 ctctttataa tcgtttccac gaagcaaaat taccgatggc tttatctttc tttagcggca
    14941 agcgtctagt gccaatcttg gctgcctttg tcatgttgct gatcagtgca gtgctactgc
    15001 tcgtatggcc tccggtttac tctgctttag tttcttttgc taaattcatt ttgagtttag
    15061 gctggggtgg tgcaggtctt tatggcttct tcaaccgttt actgatccct acaggattgc
    15121 atcaagcaat gaactccgtg ttctggtttg acgtagcagg aatcaatgat attggtaaat
    15181 ttttggcttc tgaaggaaca aaaggcgtaa caggaatgta tcaagctgga tttttcccaa
    15241 tcatgatgtt cgggcttcca gcaggagcat atgctattta cagaaatgca cgtccagaaa
    15301 acaaagcaaa aacagcttcc ttgatgctag cagcagcttt tgcttcattc tttactggtg
    15361 tgacagaacc acttgaattt tcatttatgt tcgttgcttg gccattatat gtcttgcatg
    15421 caattttcac tgggatttct ttagcagtga gtgcattctt ccattggaca gcaggatttg
    15481 cctttagtgc cggatttgtc gattacttcc tatctttgaa aaatccgatt gcgaatcagc
    15541 cattgatgtt gatcgtccaa ggattagtaa cagcagtgat ttactacttt ggctttaact
    15601 ttgctatcaa aaaattccat ctgatgactc ctggccgcga ggaagcagat ctttcagatg
    15661 acgatactgc aacgactaat tcagacaata aatatgcggc acaagcaagc aaaatctacg
    15721 ctgcattagg cggagccgac aatgtaactt cgatcgataa ctgtactaca cgccttcgtt
    15781 tgcaagtcaa agatacaggc ctgatcgatc aaaataaaat caaagccact ggcgtacctg
    15841 gtatgaagat catcgacgga aaaaatgcgc aagtcatcgt aggtacagaa gtacaattcg
    15901 ttgcagatga gatggcaaaa ctacatggtg gtgctgcagc acgacctgca caaacaaaca
    15961 ccgtggttaa aacagaaaca tttgccggtg aaacgatcga acaagatatt tacgctatcg
    16021 caaatgggaa actgattcca atcactgaag tttcagatga tgtattcgcg gaaaaaatga
    16081 tgggtgacgg ctatgctgta ttaccagaaa atggagaaat cttctctcca atcgctggta
    16141 cgatcacaaa cattttccca acgaaacatg ctgtcggaat ccaaacagat gctggtatcg
    16201 aagtcttgct tcatatgggc atcaacactg ttgacttaaa aggcgaacca ttcactttat
    16261 atgtagaaga aggtcaaaaa gtcgcaagag gtcaattgat tgctttagtt gatcttgccg
    16321 ctattcaatc tgcaggcaaa aacacggata tggtcgttgt attcacaaat ggcgacaaag
    16381 tccaaagctt agaaatcgaa cccgcacgtg atgtaaaagc aaatgataaa atcggctctg
    16441 tttccaacaa agcctgagcc atcgtcttcc ccagactttt ttatcgataa acaaacagga
    16501 gctgagacaa aaatcttgtc tcagctcctt tttccgaata aaaacggcgt tctcctgcca
    16561 actccgcggt aataagtcca gctaaacgaa acatatgaag agctattttt tatttgactc
    16621 ttcttattac ttgatgcaga acagcttttt cacaaaattt ttcttcatac tcaaaactaa
    16681 tcggcttttt cacaacctct ttatacatta ttcctgatcc aatatttctt ttaatgctgc
    16741 ttcaagagaa gttaatggtt ttcccaatac tttttctaaa tcatcagagg aaatagctaa
    16801 ctgatccttt ttaatatcat gttggatcgc taaaaacatg tcagctgctt cttgagggaa
    16861 tccggcttct tttagatttt cgacaaacgc tgcatcactt gcttcaataa tttctaactc
    16921 tttacctgtc gcacgctcta atgccttggc taattcttca tagtcagtta gattgccgga
    16981 taattctaag atttctggag agtcactttc tactagtact tttgctgcag cttctgcata
    17041 ttcacgtttc aatgcccaac ctgtttttcc atttcctgca gcataaacga attgaccagt
    17101 ttttaaagcc tgcccaatga taggtaattc attctctaca taccaattat tccgtaaaaa
    17161 tgtatgggaa atacctgaat ccttaatcat tttttcagtg aattggtgat ctggcgctaa
    17221 tacactgatc gagtgatcgg catctgcaaa acttgtataa gcgatataag ataccccagc
    17281 tgcttgtgct gccttcacta cattcttatg ttcggcttga cgatttcctg gaacgccaga
    17341 gacaaaaagc aatcgatcta ttcctttcaa cgcttctttc attgagtcta aatcatcata
    17401 atcaccaata cgtatattaa atccagcttc tttcagtgct tctccttttt cttcactacg
    17461 tactagtaca tagatttcat tttgtggaac catctttttt aagaattcca gcgcataacc
    17521 accaaaacct ccagttgctc ctgttactaa ataatgcata tttgccactc cctattcttt
    17581 ttatttgtta agatttacag ctgtacattt ataaattaca cctttatcat aaagagtgtg
    17641 gtaagataag tcaagcaaaa aaaatgaaag gatgacaact gatgaagtat tctctgcaat
    17701 ttagtgatgc aatccatgta cttgcctata ttgaaatgtt tcaagatacc cgatcacttt
    17761 ctagtgagat gattgccagt agtatcgaaa caaatgcagc aaatgtacgt aaaatcatga
    17821 gtcagctcaa aaaatccggt ttgatcttta caaaaaccgg aaaaccgcag ccttcccttg
    17881 ccaaaagtcc agatcagatt tctttactag atgtctatcg cagcatcgaa ggtaatacac
    17941 agcttatcca agtcgatcca aaaacaaatc caaattgcgt cgttggtgcg aatatccaag
    18001 aagctttaga agaaagctac gctcggctgc agaaaaaggc agaagaagaa atggctaaga
    18061 tcacacttga tagtctgata cataaaatag ccgttttgga aaaagaaaaa agaccagaaa
    18121 acacaggcct cgtagagaga tttttataat tctctctact gtgcctgcat ttttctgatc
    18181 ggaatcgtct acataaattc ttttattctc cgggggacaa aagccttgtc atgccccttt
    18241 ttcctctcta atgctcaggt caaagcgctg aagtcatgac gtcttgataa acggtgttca
    18301 agtagctgac cctcggcatt agttctgaaa aatgcaaaat atggaaagct atttcccatt
    18361 tt
//
LOCUS       DAFEIE010000049        18120 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFEIE010000049
VERSION     DAFEIE010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.050"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            168..362
                     /locus_tag="LP345_001956"
     CDS             168..362
                     /locus_tag="LP345_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760732.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..929
                     /locus_tag="LP345_001957"
                     /pseudo
     CDS             631..929
                     /locus_tag="LP345_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1026..1460)
                     /locus_tag="LP345_001958"
     CDS             complement(1026..1460)
                     /locus_tag="LP345_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1760733.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1692..2402)
                     /locus_tag="LP345_001959"
     CDS             complement(1692..2402)
                     /locus_tag="LP345_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL1760734.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2392..3252)
                     /locus_tag="LP345_001960"
     CDS             complement(2392..3252)
                     /locus_tag="LP345_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBL1760735.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3257..3895)
                     /locus_tag="LP345_001961"
     CDS             complement(3257..3895)
                     /locus_tag="LP345_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBL1760736.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3910..4209)
                     /locus_tag="LP345_001962"
     CDS             complement(3910..4209)
                     /locus_tag="LP345_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1760737.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4252..5736)
                     /locus_tag="LP345_001963"
     CDS             complement(4252..5736)
                     /locus_tag="LP345_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL1760738.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5756..6217)
                     /locus_tag="LP345_001964"
     CDS             complement(5756..6217)
                     /locus_tag="LP345_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1760739.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="LP345_001965"
     CDS             complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="LP345_001965"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBL1760740.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7520..8290
                     /locus_tag="LP345_001966"
     CDS             7520..8290
                     /locus_tag="LP345_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1760741.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8563..9390)
                     /locus_tag="LP345_001967"
     CDS             complement(8563..9390)
                     /locus_tag="LP345_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1760742.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9958..11193
                     /locus_tag="LP345_001968"
     CDS             9958..11193
                     /locus_tag="LP345_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL1760743.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12192..12452)
                     /locus_tag="LP345_001969"
     CDS             complement(12192..12452)
                     /locus_tag="LP345_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL1760744.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12479..13780)
                     /locus_tag="LP345_001970"
     CDS             complement(12479..13780)
                     /locus_tag="LP345_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1760745.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14072..14530)
                     /locus_tag="LP345_001971"
     CDS             complement(14072..14530)
                     /locus_tag="LP345_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1760746.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14543..15874)
                     /locus_tag="LP345_001972"
     CDS             complement(14543..15874)
                     /locus_tag="LP345_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBL1760747.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGRDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15885..17327)
                     /locus_tag="LP345_001973"
     CDS             complement(15885..17327)
                     /locus_tag="LP345_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1760748.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17314..18078)
                     /locus_tag="LP345_001974"
     CDS             complement(17314..18078)
                     /locus_tag="LP345_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBL1760749.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
BASE COUNT         5772 a         3738 c         2796 g         5814 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa tcatgtgttc attttttata ttagttcgaa tttgcaaaaa attgtatttg
      901 ataaagaggt gagtaaaaaa ataaaatagc tgagcattgg aggatagatt gagtgatact
      961 aagtctatcc tcttgttttt ctaaagaact aagctagaat tttttctttt gtacgttatt
     1021 atatgttatt tgtcattacc aaaaagcacc ttttttcttc tagtatctat gacataagaa
     1081 ataccaccca tttcctttac ttgaacaaat cctactgatt cataaaattt ttttgttttc
     1141 tcagtatcat ctgtcaataa ttcgatttgg actggtccat aactagtgat cttctccaaa
     1201 gcttcattca aaagcacttt gcctattcct tggcgctgat acctcggatg aatgaggata
     1261 tcttgaataa atgcgatcgt cgcaaaatca gtgatccaac gaacgattcc gataatcttc
     1321 ccttccccat tacgctttat cagagattca gattgttcaa atgctctagc taaccttgca
     1381 gtgtcttttg tgtaattcgt ccaaccaacg ctcttatata attcagaaat ctcatcgatc
     1441 ataagggaat caatattcat ttttttcttc ctttcttata caattctccc tctaataata
     1501 cagttctttg actatttaat ctatcacata taactctcct gtaaagattc tctcgattcc
     1561 ttaaaattcc tctttccttt tagaatgcat actttttgat aaataaaaag gttgtgataa
     1621 attttcttca caacctctgt ttctctctat caagtgttat cttttaattt tctaccctta
     1681 ccctagcatc tctattgccc gtagtatgca tactttccat gtttgcgaaa ataatgttta
     1741 tctagtaaat attgcgggat ttcacatata ttggggttga tcagctcgtt ttctttggcc
     1801 atcagacaaa tttcatctaa gatcaaactg ttttctactg ctttcatagg tgaatccccc
     1861 catgtgaacg gtccatgtcc atagacaagt actccaggga cttcgtttgg atctaatttt
     1921 ctttccttaa acgtctcgac aatcacattc cctgtatgaa cttcgtaagc ttctcttact
     1981 tcttctttcg ttaattggcg tgtacaagga accttaccat aaaaagcatc agcatgagtc
     2041 gtgccataag ctggcaaatc gcgtcctgct tgcgcccaca tgacggagtg cgtggaatga
     2101 gtatgagtaa tagcagttat atcttcaaaa gtttgataca aaacaacatg tgtggggaga
     2161 tctgaagatg gttttaagct atcttcttct attatatttc ccgacaaatc tgttaccacc
     2221 atttgatctg cttgcatgca ttcatatctg acaccgcttg gcttaatgac gatgactcct
     2281 agctcacggt ccacttcact cacattgccc caagtcaatt tgactaatcc gtatcgcggc
     2341 aatgccagat ttgcttcaag gacacgttgc ttcattgctg caattttttc ttcacaagac
     2401 atcatagcca gcctccttca atttagaact taagtagtct tttgcctgct ggatttctct
     2461 tcgaaagtct tggctttttt cactccacat ttcaatcaga aatgttccat cataatctag
     2521 acgtttcaaa tgtcttaata atccaagaaa atcaacacaa ccgctaccaa aaggaacatc
     2581 acgaaactgg cctgaatatt cttttgttac agggtaagta tcttttaagt ggatagcagt
     2641 gatataatcg atccctttct caagttctcg agccggatta ttttccggcc atgcggacaa
     2701 attgcctagg tctggatata cttgtagaaa aggtgaatga atctgttctt tgatttctaa
     2761 aaattttgaa atggagttca taaatggatc atccatgatt tccacggaaa gaatgatgcc
     2821 atatttagaa gcttccttta cgctttcttt tattccttcg ataaagtctt ctctggaatt
     2881 cattgatttc tcttcataat aaacatcgta tccagctatt tggattactt tgacgcttag
     2941 attatgcgcc aaatggattg cttttttcat tagttgtttc gctgcttttt tcttttctgg
     3001 atcagcagaa ccaaacggaa atcgccgatg cgcacttaaa caaatcgaat ggatacgtac
     3061 accggagctg aacatctctt ctctcagctc agctatcttt tcttcagacc aatctaatcg
     3121 tgctaaccgc tcatccgtct catcaatcga catctcgata aaatcgaagt ccatttcttt
     3181 tacaagggaa aaacgttctt tccatgaaat atctttgggt aacgcttttt cataaatccc
     3241 aatttgagcc atttccttac ccccagatac gaatgatctc atctttgaag ttttgtgcgg
     3301 ccttcatcgg atcatttgct gctgtaatac cacgaccagt gataaaggta tacacatcga
     3361 tcccttcaaa taagtgtaat gtgtgtggat ttaatccacc agttacagaa acattaaagc
     3421 ctagttcaat cagttttttg atcttcgata aatctttttc accccaagtt tcaccagata
     3481 acagcgcatc acggctttga tggtagatta cctgccggat accgatgtta tgccaatcca
     3541 tggcttgttc aaaagtccaa ttgccgtaga gttctacttg caattcacct atttcttttt
     3601 gtgctgcctc catagttgga atcgttgcac aacaaatgac tgtcatccag tctgctcctg
     3661 cttttgcaac attactcgcc actgttcctc cagcgtctgc acatttcgta tcagcgacta
     3721 gttttttatc tgggaacata ctgcgaatac agcgaatcgc tttttgtcct tcctgtaagc
     3781 aaagaattgt gcccacttca ataatatcta ctacatcacc aactttcata acatctccta
     3841 atgcatgttc taagtcattg tgatctaacg caatttgcaa attcggcctg ctcatcttag
     3901 ttccttcctt tacttgtttt tttggtacca ctttgtttca gcaaattttt cactgatttc
     3961 tttgactgac atcacatttt tgataccgat aactgtaact ccttttttct ctgcctgagt
     4021 aaacatattc aaaaaattga ctggcgtaaa aactacatcg tattggccag ctgaactttt
     4081 tccctctgaa atggcacaat gatggatttt ggtaattggt acgtttagtt ctttcattgc
     4141 tttttccaca cttctcatca tcatcaagct tgttcctgat ccatttgcac acgatactaa
     4201 aattctcatc ttaatccctc cattatgagt gttgtctaat cagattttct tttatactct
     4261 ctgcttttct gcatatgtgt catagtcttc tacaatcaaa aaataaccat caggattttt
     4321 ccgatattgt aactgcggaa tagccaataa accaatgaca actacggcaa ttccagcata
     4381 acctaggact ttcatgatta ctgtaaacaa tggccaagct gttgcccagt cgaacatccc
     4441 gatataacca ccgtatgttg acatcccaat ccatgtagcg aataatgctg aaccgcctac
     4501 ttgtatgatt cctgaaagaa acgggaacag gcaagcggct ttgaatccac ctcggttatt
     4561 ggcataaact gctataacgg cattatcaaa gaacaacgga atgaaaccgg ctatgacgat
     4621 cgttggtgat ttcaataaaa tcagtaaacc aatcatcaaa aactgtccca aagcaccaaa
     4681 caagaaccca atcgttaccg catttggcga accaaagcca aaagtagcag ctacgtcaat
     4741 tcctggaaca gctcctggta aaatcgtgtt tgagattcct tggaaagatt gagttagttc
     4801 atcgacgaat gtccgaacac ctaattgcaa gatcgccaga tataccgcaa aatttaaaga
     4861 agtcgtcata atgtagaata agaaactctg cccttcttgc atgaattgcg cttgaatcaa
     4921 ataatctttg cctagtacaa tcagaatgat cccaaagaaa aatagcatga gtaacgaagt
     4981 agcaaccata ttctcattga aaatcgacaa gaatcctggt aatttgatat cttcaatttt
     5041 tttgtcttgc ttgattgatc tatttttctt ttcatcccgc tttttcatcc actcagctaa
     5101 ttttgcaaat ataaagattc cgaacatttg ctgatgtgcc actgcaaatc cggcaccttc
     5161 tgtcaattcc tgcgtgattc ctactgttaa gttagaagct actgtccaat aacaacctaa
     5221 aatcagtccc ataaaaatca atgcttgtat cctacctaga tcaggaaagc aaaacagtaa
     5281 aatccaaaaa gcggtagctg cttgttgaac ctgaacgttt ccggtagtga aaacggaacg
     5341 cagtttcgta tatttctgaa aacggactaa taagatattt aaaacaaatg caatcagtaa
     5401 taaaatcatc acatctccaa aggtacggcc aaatgtctcc attaatccag catccacagc
     5461 attttgtcca aaataaggat ctgtaaccat ggcatccaaa ttgaaccgtt cctttagtcc
     5521 aaccaagatt ggccgaaaat tattgaccaa accaccagag ccaacagtca aaataaagta
     5581 accgaccgtt gcctttaaga atccagcgat gcattcatga agcgggcgtt tcagcaaaat
     5641 atagcctaat aacacgataa aaccaatcag gtatgctggc tgcgtcaaga tatttgttgc
     5701 aaaatacgtc caaatgctta acaaaaattc ccccatcttt tttctcctct atcaattaat
     5761 tatattctgc catcacaact tggtaatcat cgatggagtt cgtagagatg agacgctcaa
     5821 ccaatccatc tgtcattaat aattcggata atttttggat attttctaga tgttcttctg
     5881 gatcttttgc tgcgagtgta aaaaacaaac tagccgtttt ctcctcattc tccccttcac
     5941 tttcaaaacg gattggctgt ttcaacttgg taaatgaaat agctgttcca aaaacaccat
     6001 cacttttttc tgaagaatgc ggcattgcta cttgaggtgc gatcacaata taaggaccgt
     6061 atttttctac acaatggatg atctcctcca catacgtttc atcaataatt tccttatcga
     6121 tcaatacaag acagctttcg gcgatagctt cacgccaatc cgtgatttct ttatctgggt
     6181 aatgaatcaa ttgatggtca aaaaagtatt tcagcaagaa actccccttc tttcttataa
     6241 aaacgacgga aacggtgtat cattttcaat cgagaagaca tcttcaaatc ctcgataaaa
     6301 attaaactca agatcatctt tgtttgtcgg atagatgaat ttcccgccta cttgccagat
     6361 ataaggttta aatccatact tcaggcgatc ctttttgaat ttccaaattt cagtgatctc
     6421 ttttggatca gccataaaat tagaccaaat atcgtagtgg acaggaatca ctacttttgc
     6481 attcaatgac tccgccatgc gcagcatatc aacagaagta actttgtctg ttatccctcg
     6541 tgggttttca ccataggccc ctaaacagac atcgattttg tgttcattac catgtttggc
     6601 aaataaattg gagtaatgtg aatctcctgc atgataaaga ttccctcctg atgtttcgaa
     6661 taaatagttt actgcaattt gatccatctc ctgaggcatt tttcctttta atacctcttc
     6721 tggatcttca caagtgacca acgctgtccg atcaaacgct tctaaagcta ctacattgat
     6781 gtctttgatt ttgactgcat cacctggctt tactgtaatc gttttttctt caggaattcc
     6841 ccatttttgc cacgtgcgaa ccacttcttt tggcccaatg aatgttgctt caggacaatt
     6901 ttgatgaact gctgcggctg tatggatatc tagatgatcg gaatggatat gtgtaacgat
     6961 taaagcgtct acatttttta tcgcaaaagg atcgattacg aaaggctgag tacgtaaatt
     7021 aggctgcata ttttgaacgc cactcatacg catcatctga tggccttttt tcatcatgcc
     7081 attcccatga ctacgttttc ccgtcccaca ccatagatca cataaaatat tcgttccttc
     7141 atgacttttc agccaaattc ccgtacagcc cagccaccac atagcaaaag ttccaggatc
     7201 cactacttct gtttcgattt cttcattcaa gtatgtgccc cactcaggaa atgtttctac
     7261 taaccacttt tcttttgtta cttcattgac agttttactc atttgcttgc tccccccata
     7321 tcgttgttcc aacttacaag taaatattaa tgtgtatcag catccatgaa aaccctttta
     7381 tatgaccgtt tgttttttat atgattttct ttcagtaatc aatgattgtt tcagtataat
     7441 aaagacagat atgaatgttt aaatgaacaa ctagtcaaat aaatccatgg atcaagatgt
     7501 ccctcaggag gcaaaagtca tgaaaaactc acttgtcaat attgaaaaac gtcaaaaaga
     7561 aattttggaa ctgcttcagc agactgaaca actatcaact ttcgaattag ctgaatccct
     7621 tgatgtatct attagtacga tacgaagaga tttaaattta ttagaagaaa aaaacgagat
     7681 catacgcaat tacggttatt gttcttataa ttacaaaaac cagactgatt ttgatcaatc
     7741 tggtcctgaa aggattaaac aagcgattgc cagagaagct agtaaataca ttaacgatta
     7801 tgatacgctg tttatcaatt ctagctcgac tgcgttgaaa acactggatt ttcttcaatc
     7861 taaccatttg acagtcatta caaacaacgt gaaaatcaat tactctccgc acaaagataa
     7921 ttgtagttat attttaactg gtggagagat gcgctttcca aaagaagcac tagtgggcga
     7981 catcgcatta aatacgattt cttcagtcaa tgcagacatt tgtatcattg gctgtagcgg
     8041 agtcgatgta gtacatgggg tcacaacaaa gatattaaat gaatcaacga tcaacgaaat
     8101 gatggtcaac aagacaatca aatgtaagat tttagtcgct gatcatcgaa aaatcggact
     8161 gacatcaaag ttcaagattg ctgatatttc agtctttgat tatttgatca ctgataaatt
     8221 ttgttctgaa aaagtattag aggagatcag aaatacgggg ataaaaacca ttcaagtaga
     8281 ttcattttaa gaaccaggac gtaaatatgt aaataggatt atcaaaaaaa tgaataacaa
     8341 atttatcgat aaatgaaaaa cacgctacgc tcaaattgat aaaggaatcc caagatgtat
     8401 ccatccaatc gataccatca taatctattg cttcttttat aaccgttata tgttgcctaa
     8461 ataggaatca aacaatatcg aaaaaaggag gtatgacaaa agtcacacct ccttttttcg
     8521 aataaacggt attcaaatca gaacactgat ttcacaacca ctttatttca ggtcgttttc
     8581 aatcaccttt accgcgtaat catttccgtt gaaacgcgct attttttttg cgtccatata
     8641 tctttctaaa taatcatctt ctcctaattg cttatggcaa gaagcaattt cataaagcaa
     8701 gtattccaat gcataagtcg atttatgttt cttattatac tcaataccct tctcacataa
     8761 ttggattgct ttatcataat cctcgatttt acggtaatag gtggcgatat cataatatac
     8821 aatgcagacc atcagattat caaaatcagt ctcactcaat attttaagtg tacgctccac
     8881 ataaactttc gcaaaatcta attctccttt tgacaagtag atcattgcca cgtttgcagc
     8941 tgcttgtaag tgatggatat ctgtttcggt cgtttgttcc aacacttgat taaaataaaa
     9001 taatgctgca tctggttttt tcgcataaag atgatcaagc agtccttgat aaaataaaat
     9061 ttgatttaaa agatcagaat tacttacttt ttcctgatcg atcgtttgta aaattttata
     9121 agattcttgg tattttgata cagaattcaa tgattgaatc tcatttattt ttttcctgat
     9181 tttgtcttct tctgtttcta ctaatatatc ggagatctcg acattcagct ttttgcaaag
     9241 cgcacttaag atattgatgc ctggcgacat attcttgttt tcgatattgc tgacagttgc
     9301 ttgttcacaa atgccttctg ctaattgtac ttgtgttaac ccctttttct ttcggtattc
     9361 ttttagtaat gctccatcta ctttaatcaa aacaatttcc ttccctttaa aaaattattt
     9421 ctcctttata tcatacacaa aaaaaagttc taaacaacca aaaatgttta gaacagaata
     9481 aaaattttaa ttttaaaata atattcaaat taaacaactg gcgtatctgc tccttgattt
     9541 ctttttgtgt tatctgaata attatcgttt acagttataa cacatagtga aaattgtcat
     9601 ggcgagaaag tctaagaata tttttaaaca taactatttc tttcttacgt gtgtataatg
     9661 acgacagcac acctatcaat taatataatt attttatttt tttatgttct catgtttatt
     9721 tttaatgaca caacttctcg tatttatctg gcacaacata taaatcgatc aaaaaattgt
     9781 tgcgtgtttt tttgaaaatt ggagtttcaa cttgattaca aaatttaaat ttagaagttg
     9841 tgaaaacagc gagagacagt ttaatattca aaatatacat aggctactcg aacgctgtgt
     9901 tttttagtat actagtaaga aacgaaggga tagactcatt ccaataagga ggatttcatg
     9961 aagacaattc tttttgctcc tgcagtattc aatttagctg agacaacacg aatgattgag
    10021 gttgccaaag ctatgaaaga ccgttattac tgtgtattct ttggcttttc taaaactttt
    10081 gctcctttga tcacagaaag tggctttgag tatcatttac tagcgccgat ccttacgaaa
    10141 aaacaagaag aacaaatcat aaaatttgac cagttgcgta cacttaaaaa cccttttacc
    10201 aaagaaatgg ttgcctctcg tatcactagt gaacagagtc tgattgctaa gtttgagcct
    10261 cgactgattg tgacaggttc gaatgtgaca atttttttat cggcccgcaa taaaaagatt
    10321 cctttagtat atgttaaacc ctatgctttg agtgaacctt tttttcaatc agagcatgcg
    10381 ctgatgcccc acgagttacg tttcttcggc cctttaagca atcccctttg gcactggaca
    10441 aaaaagcgta tagtaaatac ccgatggatc cccaatgcct tcaaacacgc tgcacaaaaa
    10501 gaaatgcttc ctttaccaaa aacaagttta caaatgatgg atgctgatct aaatctcatc
    10561 acaacgccta aactattttt ggaagaagaa cagctgccgg aaaattatcg aatcgttggt
    10621 ccaatttttg ctaagctcag tacttccttg cctgaagaag tgctaacttt tatacagcga
    10681 aagcaacaag aaagaaaacg tattatctat ttcgcaatgg gtagttcagg caatccgcgt
    10741 atgttacgca aaattttgtt cttcttacaa aaacaaccgg atctagcggt tattgcacct
    10801 attgactatc tgcttgatga cattcaatct gactcagaag atcttttaat aacagaatat
    10861 ctgtctagtc atcttttgca tgaattcatt gatttttctt ttatccacgg cggggaaggg
    10921 accgtccaaa ctgcctgtga atccggcaaa ccgtttatcg gtgtggggat gcaatttgag
    10981 caaagctgta atattgacta ttgtgtaaaa tacggaaacg caatcgccct cacaaaacca
    11041 gtgactgaaa gaaaactgca gattgctctg cgcgaagttt cttcacccaa gattcgtcag
    11101 caggcacgca cgctgcaagc cgtttttcca ataaatggtc cacaacaagc aattcaagaa
    11161 atcgaaacct tcctgagcaa ccacccaata tagtttcaag tagaaaaagc ttttttaata
    11221 gagactcatc agtaatttcg ctattcgaga cccagacagt gaaaatacaa aaaaagtaaa
    11281 tagtggattg aaaagttaga gttacttaaa ttacggtgtc taaaaaacac aaaatcatcc
    11341 ttaaaataaa agatctgacg ctatccaaat gagcataggt agcgtctgcc atttattctt
    11401 agtcaaattc tttgacacct ttctctggtt ggatcatctc aacgtttctt caaaagaaag
    11461 accataataa ttaggcaaat acattttctt aaaatgtgtc atatagatct agaagcatcg
    11521 ctttgtagag atttgtgccg ctagtcccct caacaattac taaatcaaat gtaggattta
    11581 ccactttatc tttgataatc aacctccctc ttctgttgag acaatgatct cgcaatccga
    11641 tgcatactcc tatataaact gccagcaatc cccacatatt gagtagatca tgtcagaatg
    11701 ttctatgtcg tcagcaacga tacactaaaa gtcacgttca ccatgactga ttgctattcc
    11761 cagcacaatt atttctatac acgtttcatg atttgaataa acactcacat catacatatt
    11821 accattcata caccatactg cagcccctac tatatggttg taagctccca aatctatatt
    11881 tgacttgatc actttggtag tagatctact aattctaaat ccattgctga taaaatttcc
    11941 attttttcct ccttctttct gccaaaacag ttaaaacaat aataatcttt atgtaaaaaa
    12001 gggctgtgac aaaagccttg tcacagtccc atattccgaa taaacggtgg tcaaaagctt
    12061 gcatctgcgg taataagttc aaccaaacga aaaataagcc aacatttcac aaaaatttaa
    12121 gaagcaattt tcgtaaattt cttcttattt cttgaagcta accacttctg ttacaaccac
    12181 ttttagaaca tttaaagctt cgatgtgaca aaccatctat gctgctcgat cataaaattg
    12241 atagcaaaaa ttccacaaag tacatatgtc ccccatgaaa acaaaacatt catatgcggt
    12301 acaatgatct ttggaagaat cacgatcaaa aatgatgcca gtgcccaaat ccatcgattg
    12361 atttgaatat gatatgtagc tagcatattc aatataaggt gactagccgt taataaaaag
    12421 ataaaaacaa aaaataaaat cagccaatac attgtttccc accttctaaa aaccaaactt
    12481 agacagtctg gacttcgttt tctccacgac tttgttcatc tgacagcatc tttttatcat
    12541 aagcttttac aaatggataa tagataataa atgctatcaa tgtgttgatc atgatcaaga
    12601 taacaacacg ccagtcattt cctgctgaaa gataaccgcc gattggagct ggtaatgtcc
    12661 atgttggcaa aacagtaaat ctattgacca tttctaattt gactgcaaaa taactgataa
    12721 tagtcaaaac taaaggaact aagttgaacg ggatgaacat gtaaggattc aacatcatag
    12781 gagctccaaa aattatgggc tcattgatat tgaagatacc aggaataata gaaaaacgac
    12841 caacctcttt caagaatttt gatttacaga agaatataaa caaaacagat accacgatcg
    12901 ttgctcctgc accaccaatt gttaccgtcc attgataaaa ctgttcagga gcgatatagg
    12961 gtaattgggt ggcagctgta ccatctgcca atgcctttgc attctcatcc aacatgatca
    13021 gccacattgg acgaacaaca gcccctacaa tactcatgcc atggatacca aatgaccaca
    13081 acaaatggat caaaaacatt ggtagtaaaa caccaagcaa attattccct aaaatattgg
    13141 ttaaaggctc gaataacgat aataaggcag cgtttacatc aaagcccgcg acgcttcgaa
    13201 tcagccaagt aattgttaaa atgactgcac ctggaatcaa tgcctcaaaa ctacgggcaa
    13261 cagcaggtgg cacttgttct ggcattttga tagtaatatt tcgattttta aagaaacgat
    13321 atacttccac tgcaaaaatc atagataaga tccccgcaaa catcccagat gctcccaaag
    13381 aactcatagg taagacccag ccaagaggtg cctcttcagg agttaaaacg tttacaggaa
    13441 cttgtaacat aaagaacgtt cctaaagata atataccacc tgtcacacta tctaatccat
    13501 atgatttagc tagatccgaa cccataacaa aagttgcata aatagccatc aatcccatcg
    13561 tcatcctaaa gggtaaaaca atcgttgccg aataaggggc aataaattca ttccatccag
    13621 gaaacggtaa attgataaag accataaaaa atgtcccaat caaaatcaat gacaatgttg
    13681 aaacaacccc attacgaatt gctaataaat gacgctgtgt accaattttt gccattggtg
    13741 ggacaagttt ctcttcgacc catttcatca gcttttccac taaaaccact ccttttcaat
    13801 aaaatatgaa ccattcattg catgacaacg caaagaatgt tcataactaa ttatataatt
    13861 aagaaatttt atttcaatat attctcttaa ataatcaaat ttatttttaa gaatcctgaa
    13921 aataagtttt ctaaatcata ggagcaacaa aaaaattcga taattaacaa aaatcaaaat
    13981 gattaaatct agtgattgaa acatatcatt tcaaaaaaat tttgtaaatt cacccataaa
    14041 tatcacccta tttaactttt ttcatcgtac actaaaattc aaaacaacta tctttaatct
    14101 ttacttcttg gttttgtttt aataaatttc cttcaaaaat gcctggagaa actacaatga
    14161 tcaccgtatc tttttgtgct tgctccaact tcttcaaatc tataatagct aacagtgtcc
    14221 cttcttttac ctcctggtta ctttcaaccc gtatctgaaa cggacttcct tcgagttcaa
    14281 ctgtatctaa acccatatgg atcagtattt ttctgccaga ttcactttcg atcgttatgg
    14341 catgtcgggt aggaaatata ttatcgatta ttcctttaac tggcgcatgg atatatccat
    14401 catgattcgt tatagcgtat ccaactccta tcatttttga agaaaagacc tcgtctttta
    14461 ctgctgttaa tggaataatt tgaccactag ctacagcttt tagaatgttt cttgttttaa
    14521 agaaatgcac tttttatcac ctctacttta atgctggcca atattttttg tttactttga
    14581 tcatttcatc tagtattttt tttgcgactc tggcatttgg tacggtttga ttcaatgtaa
    14641 atgcttgtaa agctttttga taagaacctt caaagtaagc atctactagt aacttctcta
    14701 ctgcaacttg tgcctccatc aatcctttat gaaaatcact gattggtttt cttagtgtaa
    14761 ttggctccac accagttgca ccaacatatg ccggtatttc aacaactgca tctgaccgta
    14821 gattcggaat cgccccttga ttaggaacga ttagcataaa gcgacgacga tcatcattca
    14881 acaaggaaat agctatatcg acgatatatt gtccatgctc cccaaaatta aagttcaata
    14941 cttcttccac aataccgcgg cgtattttat cagccatttc tttggtattt ttctctcgtc
    15001 catccatgac catattagca cgtgtatact ctttgtcagt atgctcaacg accatatcag
    15061 gatataagta atactctaag taattattcg ggatattact tggaaaattt ttcgtgatga
    15121 ctgacatcat ttgaaaggtt ttttgccaag ttttatctcc tatattaaaa tcggcgactt
    15181 gcatttcttt tgttattagt ttttcaataa tctctggcat aatttctcgt tgcaattctt
    15241 tatcataaat cgatgtatac cagccaaagt ggtttaaacc ataatacgta acgatccaat
    15301 tcttacgatc ataaccgtaa ttcactgcaa tcgtttcttc aattgaaata gtcatatcac
    15361 aggcattaat catttttaca ttcggatatt tacgacgaac agcttcagaa acgatcgact
    15421 ctggatttgt ataattcaaa atccatgctt tgggggcata gtcttgtata tgatcgacaa
    15481 tttccaataa acctttgatt gagcgcatcc cataagcaaa tcctccgagt ccacacgttt
    15541 cttgtcctac taatccatgt ttaagtggaa tcttttcgtc cttttctcgc atctccaatc
    15601 ctccaacacg aatttgtgag aaaacaaaat cgcgtcctgt aaaagcaagc tttggatcat
    15661 ccgttgcacg aatgcgaata tttgaaaaac cttttctttt cagcataaat ttaacaatca
    15721 agtacatatc catatttctt tcttcatcaa tatcatataa acgtatttca gataatggca
    15781 accgtttttc attgttcaaa atggcttgaa cgattcctgg tgtatacgta ctcccgcctc
    15841 cagctatagt gataatctgt tttttcatca tcatcttttc ctttctattc ttctaataat
    15901 ttattgaatt ctgccataac ataagtcact tctaagccga tgataatttg ataatttttt
    15961 tcagttggtt taatgatccc gcttatccct aattgcttga ttcgctgttc ctcgaccatg
    16021 gtgggatcca ctacctctac ccgtaggcgt gtattacaac tatagacatc caggatattg
    16081 gcttttcctc caaacgcttg tagcattttt gttgccatat attcataatt tttacttgct
    16141 aaccctaact ctgtttcttc taaggttact tcattgccaa actctgcctt agcttcacgt
    16201 cctaatgtct gaatgtttct cttattgatc aaataataaa aagtaacgta atacaaggca
    16261 aaaaagaaaa ttccgattgg aagaatcaaa atagcattgg tagcgattcg aaaattgatg
    16321 agataatcaa caatacatgc tccgaatgta aaaccaattc gtatattgaa taagtaacag
    16381 acaatccctg ctaaaccggc aaaaagtgca tggatcacgt acaacatagg agaaagaaac
    16441 atgaaactaa attcaacagg ctcagtgata tttgcaataa atgaagttcc tgcaccgctt
    16501 cccatgattc ctttgaccat ctctttattt tctttataag ctgctttata gatagctaga
    16561 catatagctg gtataccaaa catcattact acaaaaaaaa ctgataaaaa cagtccagcc
    16621 tgaggatctc cgttgataaa gcgtgtcatc tctcctctga aaacttcctt gctaggagat
    16681 gtatagcttc ctaaatcgta ataaatatac gtattcaaca catggtgcag tccaaagggg
    16741 atcagcaaac gattcaaaaa cataaatatc cccacaccta atgctcccat atcaacgagc
    16801 agttttgcaa aattatcaat cccaatttgg atgagcggcc agataaagcc caaaaaaaca
    16861 gctgcgattg tttgtagaat catcaccata gtcaatggga atttttcgcc cgcaaaataa
    16921 gaaaaaacta ctggtaattt ttgttcttta aagcgattat acgtccatgc cgctactaaa
    16981 ccggaaataa ttccaccaaa aatccccata ttcacttctg ggtccataat ttctaagcct
    17041 tttttcaagg tagcaatcgc taaaaaacca gtaagtgcag gtattccttt gtccttattt
    17101 ttgacaaaac cgattgcaac tcctatagca aataagatat ccaagtttcc aaaaacggca
    17161 tttccagctg caccaattac tgggatgttc agcatatcgt cagctgataa acgcatgatc
    17221 aatcccgcta atggcatcgc tgcaactgga agtagcatcg ctcttccaag cttctgcaca
    17281 tttgatttaa cattcatttt tattcctcct ctattaaata tcctcatatg ttactaactc
    17341 aatcaaagga tcatttttca ctttttgagc aaatgctgaa tgaattaaaa attcgacttg
    17401 gtgggtacga ggatacacaa aacttgaacc atttaacaat tcctgatcca aatacgctgc
    17461 gtgacacatg acttcgatcg ttttatcttc tctcaatatc atgagtaaac ttgccaaata
    17521 ttcttccaca ctcgtattga tttgtcgttt tttttcatca gtttctccta cgacatcgaa
    17581 acaaggctca aaataatcga catgacgaac ttcatctttt cgttcaaagt tgctccgaac
    17641 cggcaaatca tatttttttg ctaatgtaac aactacctcc tgattttcat ccaaagtatg
    17701 agtatgatga tgactgtcta aatgagttgg tatgatcccc gcatgataaa ttttttgaat
    17761 ctgagcattc cattcctgat acagttgatc tttgtcaatg ttaaatggat gctgataata
    17821 agataaggat ctgaactctc cgctttcgat aagagtatcg acagttttga ggagtggttt
    17881 gccacacgtc aatgttaaat ggactcctac acctagccta ggcatttcct ttcttagttt
    17941 cacagcatgc tcgaaacccg gcatatttgc catcaatgta gttgatgtca aaattcctcg
    18001 ctgataagca tccataatcc cataattcac accatggcta tagccaaaat catccgaatt
    18061 aaaaatcact tttcccattt cattctcctt cttttttcta ctaaaatagg cgcaaccaaa
//
LOCUS       DAFEIE010000050        17872 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFEIE010000050
VERSION     DAFEIE010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.052"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            205..2088
                     /locus_tag="LP345_001975"
     CDS             205..2088
                     /locus_tag="LP345_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL1760750.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(2163..2447)
                     /locus_tag="LP345_001976"
     CDS             complement(2163..2447)
                     /locus_tag="LP345_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL1760751.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(2437..3171)
                     /locus_tag="LP345_001977"
     CDS             complement(2437..3171)
                     /locus_tag="LP345_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBL1760752.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            3300..3923
                     /locus_tag="LP345_001978"
     CDS             3300..3923
                     /locus_tag="LP345_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBL1760753.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            4115..5236
                     /locus_tag="LP345_001979"
     CDS             4115..5236
                     /locus_tag="LP345_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBL1760754.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            5243..8371
                     /locus_tag="LP345_001980"
     CDS             5243..8371
                     /locus_tag="LP345_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBL1760755.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            8390..11584
                     /locus_tag="LP345_001981"
     CDS             8390..11584
                     /locus_tag="LP345_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBL1760756.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(11730..12437)
                     /locus_tag="LP345_001982"
     CDS             complement(11730..12437)
                     /locus_tag="LP345_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1760757.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            13202..13600
                     /gene="spxA"
                     /locus_tag="LP345_001983"
     CDS             13202..13600
                     /gene="spxA"
                     /locus_tag="LP345_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL1760758.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            13932..14585
                     /locus_tag="LP345_001984"
     CDS             13932..14585
                     /locus_tag="LP345_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBL1760759.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            14811..15809
                     /locus_tag="LP345_001985"
     CDS             14811..15809
                     /locus_tag="LP345_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBL1760760.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            15985..17793
                     /gene="pepF"
                     /locus_tag="LP345_001986"
     CDS             15985..17793
                     /gene="pepF"
                     /locus_tag="LP345_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBL1760761.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT         6125 a         3007 c         3716 g         5024 t
ORIGIN      
        1 tttttctacc atagtagaat cagcaaagaa aaactgcttt tttatttgaa attttcttaa
       61 agttgaaaaa aagcatgttt atttttttaa atttatggga tgatagaaaa aaatagtaga
      121 gaaaggacac gattctactt gctattttca cttaataccc gtatattacg aatgaaaaaa
      181 gtttatgaaa agttggaata ttgaatggaa aaacaaaaaa ggttaaaaaa cagccgctac
      241 atcactgggt ttgatgggct ccgttcatta gctgtggtgg gtgttatctt ctatcacctt
      301 ctgccaacta gtatgaaagg cggctatttg ggcgttccga tttttttcgt cgtatctggt
      361 tatttgatca cggatctgct gcggcaggaa tgggaacaaa atggaaaaat caatatttgg
      421 caattttatg tcagaagaat gaagagactc tatccggcac ttgtttttat gcttgtgaca
      481 gcttcggctt atatcacttt gtttcagcga gggctgttaa acaatcttcg aggagttgtg
      541 gtcagcagct tactgtatgt caacaactgg tggcaaatca ataacggttt atcttatttc
      601 gatcgatttg ctaatgagtc accgtttacg catatctggt ctttagcagt agaaggtcaa
      661 aactatttgg tttggccgat cttgtttgta ttgttgatgg tatttgttcg taaaagaaaa
      721 tggatctttt atactgtgtt aggtacatcc ttcctctccg ccatcttgat gatgatcttg
      781 tatacaccag gaggcgatcc aacccgtgtt tattacggta ccgacactcg tctgttttct
      841 atatggttgg gaagtgcgct tgcgtttgtt tggccaagta cgcgtttaaa gaaaaacatc
      901 ccgaaacaag cgaaaaatat tctgaatatc gctggaggaa tctcgctttt ggcactgatt
      961 ctttgcttct tctttttaga tgatcattac aatttcatct attacggagg aatgctccta
     1021 gtgagtctgt tatgcgtagt gctagttgca gtgacagcac accccggagc aagtttgaat
     1081 cgatggctga caaatccagt atttacttgg attggcaaac gaagctatgg catttatctg
     1141 tatcagtttc cagttatgat tttttatgaa gcaaaggtga ctgatattgc cgatcatgtt
     1201 ttgttgcata ctttagtgga aatcacattg attctaatca tcagtgaact ttcttatcga
     1261 tatgtggagc gtccgctagc acgttttgat tatggtcgta cattccaagt gatgaaagga
     1321 tggttcagca aaccgatcat cagtaagagc aaaccatggg ttgttccagg cacattactt
     1381 gtagcaattg cactcgttgg tttcgttacg gcaccgaaaa acgctgtaac agccgatcaa
     1441 aaacaactgc aggcaaaaat cgctgaaagt aaaaaattag cagaagaaac cagaaacaat
     1501 tcagaaaaca ccactagttc ggttgaccaa gcgatccttg ataagtacga gttgtccaag
     1561 gcacaaggga ataaggcaca aaaattagaa ctaacggcat ttggtgattc agttatgttg
     1621 gatgctgcaa cggatctaca agaactttat ccaaaagtag tggtagatgg agatgtcgga
     1681 cgacaattat atgccagtgt accgtacatt gaaaaattaa aggaacaaga tttgttgaaa
     1741 gacactgttc tgatcggact aggaacgaat ggctcattct cggaagctca gtttgatagt
     1801 gtgatggatg caatcggtga tcgaaaagta tactgggtca atgtccgagt accgacgaag
     1861 cgctggcaaa atgacgtgaa tgcgatgctt gaacagatga cgaaaaaata cgacaatatg
     1921 acgctgattg attggtacag ctacagtaat gaccatagtg actggtttta tgatgatcaa
     1981 gtccatccaa atcctgaagg gatgacacat tacattcact tagtcagcga agccttgcta
     2041 ggaggaagtt caagtacgaa cagcagtgag acaaacgtga cagaatgata gctacaaaaa
     2101 acttcaggca aaaacatttg tttttgcctg aagttttttt atatttaccg tgtttttaac
     2161 attcatatag attcaggaag caaaacggtt gagtgtgtct gtaaataacg ttctttttgt
     2221 tttcgggtga gttttttgaa tgcagcttct gcttttgttg cttcgcttct tgaagaaaat
     2281 acttctgcat ggatcatctt aacaggtctt cttttttgaa gacgagtata tttagcacca
     2341 gtaccattgt tatgttcctc taatcgtcta gaaagatcgg ttgtatatcc accataaaat
     2401 gtctgatctt tacagaataa tacgtaaaaa taatgttcat ttgccataga gcatctcacg
     2461 aatctctgca gtgtattctc catccatatt gtaagtgatc aatggtggag cgactttgaa
     2521 tccgtctaat ttgccttctt tgattccttc aactaacaaa atatttgcct cttttccagg
     2581 ttttgggtaa acaaattgga tccttttagg tgcaattcga tagtcttcca tgacctgaat
     2641 gatttctaag aaccgatcag gacgatggac catagtaaag cgtccatttg tttttagtag
     2701 cttacttgaa atatcgatca cttcttctaa cgtcgtatga atctcatgac gggcgattgc
     2761 caggtgttta ttagggttcg ttttatttgt tggcagccct ttgaaataag gtggattaca
     2821 gacgactaag tcacaagaat tatgtcgaac gacagataag ctgtctttca gatcgatggt
     2881 gtggacagtc atttgttcat ttaaatggtt aagcgcgata ctacgtcttg ccatgtctgc
     2941 tagacgaggt tgaagttcga tagcgtcgat agccgcctgg gttcgtttac ttaaaaaaag
     3001 tccaactgcg ccatttcctg cacaaaggtc aacaatcttc ccttttttag gtacacggga
     3061 aaagtgagca agcagcacag catctaaaga aaaagaaaac actttggaac tttggataat
     3121 cttgatatct tctgcgtata attggtcgat tcgttcgtct tcgtgaagca tggattccct
     3181 ccaaaatgaa aaaaatagtc gtctgtatta tactattttt attaaaaaga accaaggtgg
     3241 cttgtcaaac ctctattttt tatgcatact atgaccataa gaagggaaag gaagagacta
     3301 tgttttatcg atttatgcgc ggggtagttc gagtactatt agccttagtt aatggaaatg
     3361 cccgctatga gaataaagaa gttttaccgc aagatgagaa ttacatacta gttgctcccc
     3421 atcgtacttg gtgggaccca ttatatctgg cggtagctgc agcacccaag gaattcagct
     3481 ttatggcaaa agaagaactg ttcaaaaatc cagttctgcg atttatatta actcgatcca
     3541 atgcttttcc agttaaaaga gaaaatccag gaccaagcgt cattaaaaca cctgtaaaga
     3601 ttttgaaatc gacaaatttg agtttgatca tgtttcccag tgggacaaga catgctacag
     3661 aacttaaagg cggaatggca ttgatttcca gaatgtctaa agcgaaaatc gtgccagctg
     3721 tatatcaagg tccgttgaca cttggggatc tgttcaagcg tcagagagtg acagtgcgtt
     3781 tcggcgaacc aatcgactta tcagatatca agaaaacgga taaagaaggt atggcggaga
     3841 tcgaacgacg aacacaagca gcttttgaca aattggacaa agaagtgaac cctgatttca
     3901 aatatgaagt caaaaaaaaa taaaatgata agtttatgcg tgggcggtct tttgaatcta
     3961 ctgtcctgtt cagttcagac tttttcaatg aaaacgaggg agagacgtca agtctgccct
     4021 ctttttgcgt tccaatatgt aaaatagaag acaggtgtca tgtaatggat caaagtgtta
     4081 taataattag aaggacattt tttgaggtga ttgaatgcgt tttttacata cagccgattg
     4141 gcatatcgga aaaaaactac aaggttatga cttgattgaa gaccagcgtc atgtactatc
     4201 ttctatacta gatatcgcga aagaagaaaa agtagaggca atcgtgattg ccggagactt
     4261 atatgatagg agtgtcccag ctgttgatgc cgtagaatta tacaatgaat tgatggtcga
     4321 ttggaattta aaggaaaaga tcccgatttt tgctatatca ggaaatcacg atagcagtac
     4381 gagactttca gcgggtacgc catggttcag ttattcgaac tattttttgc gaacacagct
     4441 agcagaagca tttgaaccag tcgagtttaa aaacgtacaa tttttctttc ttccttactt
     4501 tgaaccaatt gcagcgagat tatattttga agatgacaat atccgaacga tcaagcaagc
     4561 ggtagccaag gtgatagata aaatgcagga gctatttgat tcagaaaaaa aacaagtatt
     4621 gattagccat ttttttgtaa tgggaagtgt aaaatctgat tcggaaacga aaatcgaagt
     4681 aggcgggttg gattcgatcc ctggtgaact acttacaccg tttgattatg tagcactagg
     4741 acatttgcat aatcaagctg ctttgagaca ggataatgct cgctatagcg gttccccatt
     4801 gaaattctct ttatctgaga tcaaccaaaa aaaaggcgta tggatcgttg acctgacaac
     4861 aggcctggag ttgaatttta gggagatcga acccctgcat gatattgaag aaataacagc
     4921 gagtttcaaa gaattgctgg atcctgcctt ttatcagtcc gtcaatcggg agaattacat
     4981 ctatatctat ctcactgata gaacgatcat cccgaatatg atgaaccagc ttcggcaaat
     5041 atatcctcgt attttgggga ttgaacgggc aaacggtcga gcagaacaaa caaagcgcaa
     5101 acgaaaagta ctagaaatga aagatcctca aaaattagca gaagcatttt ttagtgaaat
     5161 gacggaagag cagctaactg caaaccaaga aaaatggctc ggagaaacgt tgcaagaaat
     5221 catggaaatg gaatgatcaa gaatgaaacc gaaaaaatta caacttaaaa attttggtcc
     5281 ttttatcaat gagaccgtag atttttcacg tttgacagaa gcaccgcttt ttttgatcag
     5341 cgggaagaca ggagctggca aaacgacgat ttttgatggg atcaccttcg cactttttgg
     5401 tgaaacttcc ggaagacttc gctctggaaa agagatgcgt tctttgtttg ctacaccaga
     5461 cgaagaaaca agcgtgactt tttcttttga acatcagcag atgagctatg aaatcgaacg
     5521 aaaaccagaa caagttttag caaaacgaaa aggaaacgga acaaaaaaac aggcagccaa
     5581 agtaacgttg accatttttg atgggaaagg aaaagaaata aaacaaatca caaaacgtac
     5641 agaagcagat cagttgatca gagaactgat gaatctcgat gcgaaacagt tttctcaaat
     5701 cgttttacta ccccaaggag aattccgtaa ttttttggtt tcatcaagca gtgataaaga
     5761 gactgtttta cgtcatttat tcggtactca atttttccaa cagttcaatg agcgattaaa
     5821 agaaaaagca aaacaacagc aacaaaaatt ggatcattta gagcaagagc tgcatcttct
     5881 gcaaaaaagg tttgttttag tcaaagaaga ggaaccagca gcagggtttg aagccgtttt
     5941 agcccaatgg acaaaccatc aggcaatact cgaaaaacaa atcacggaag aaaaagaagc
     6001 tctaacggaa cttcaggaaa aacaaaagca actagaaaat tcctactatc gttttgaaag
     6061 cttgaaaaaa agttatgaag aaaaaacgat attaataaac aagcaaaagg aattagctgc
     6121 tcaaaaagac gaaatagagg aaaagaaacg atggattggg tattatgaat ttacgcaacg
     6181 attagtcgaa ccaatccagc gcctacaaga aataaaagtt gaaaaaatag aactgtcaca
     6241 aaaaagtagt gagcaaacaa agaaactagc gatgactacg cagaattatg aagagtggca
     6301 aaaaaatgaa gcaaaccgcg tacgccgaca aacaaaaatc aaagaagctg ctcaaaaact
     6361 gcaaaacaaa cagatgatgg tgccaattgt cgaatcctta cgtagtaaaa aacaagacgc
     6421 agaacaatta acaatttcat tggataaaga agaattgaat gccgagaagc tgtatcaaaa
     6481 tctcgctatc tatcaggaaa gaactcgaat tcttcaagaa aatttactgg atcaggaaaa
     6541 actgcaagaa gatcgtcttg cttttggaca gttaaaatat ctagatgaaa agcagcaaga
     6601 aatagaaaaa caaaaagcaa aagacactgg gtcgctcgca cagataagag aagaactcaa
     6661 aaaagcaact gaagaaataa caaaaaatag tcagctattg aaagaacaga cagaacaagc
     6721 agaacagctg aaaagccaat gggcaaagca gcaaattgct cgtcttcagc tttttttgcg
     6781 tccaggggag ccatgtcttg tttgtggatc aacggaacac cccatacaac aattaaaaca
     6841 cgaacagcca aataaggaag atatcttaaa agtagaacaa caactggcag aagctgagtc
     6901 tgctgtagaa agaactcagc aaatcattgc caaaagtgaa gcacatgaaa ataatcttca
     6961 acaacaatta tcagatttag aacaaaaaat catggcaacg aatatacaat tggctgaaca
     7021 agaagaacac ttgcaacagg ctttgaaaaa ggcatttcct gagataacag aacaaaaaac
     7081 aaaaacaact cttgtagtaa tcgaacaatc tttagataga cgaaaaagca agatggccaa
     7141 tgcaagaata gagctggaag aaataagaca acaagcagaa aagctcgaac aacaattagc
     7201 tgtctacaaa cagcagcaga cagaaaaaaa taatcagctc cagcaactgc aaggagaaat
     7261 caaaagttta gaacaacaat tgcaagatac ggatagtaac tgtttagaag aggagatacg
     7321 acgacttgaa aaacagttag aagaagactc gaatcaacta gctgttgagc agaaagcagg
     7381 agtgcaattg ttgcaagatc ttcatacgct tcggacacag cttgatcttc aacatgaaca
     7441 aatagaaaaa atagatgaaa aaatagaaaa ggaacaagaa agaatagcta aaaagttaga
     7501 aagccagtcg tatttttcaa caattgaaga aatctgtgca tttgcacaac agcaagcaca
     7561 atataaagaa aaccaacgta cagttacttc ttatcatgaa gagcaattag tgacagctga
     7621 ccggctgcgt caattagaaa atatccagct aactgagaca ttcccagata cagaagagat
     7681 cagccaacag ttagaagaaa taagacgtat gatcgaaata aagcaagaaa agatatacgg
     7741 tttacaagaa caaaaaatta gtaatcaaaa aatctacgat gaatgtcttt cgatttatca
     7801 cacaagccag acgaaattag atgagcttac gcaattacag cagctttcgc aaacattcaa
     7861 cggagaaaat cctaagaaga ctagtttgga acggtatgtg cttcaggttt atcttcaaga
     7921 agtgttacaa gtagcaaatg atcatctcca acgtttaacg aaaaatcgtt atcaatttga
     7981 gctagcggat accattggca gttatcgagg gaaaaccgga ttagaaatca atatctatga
     8041 tgatcaggca ggtatgtctc gaagtgcgca taccctgtct ggcggtgaga gttttattgc
     8101 agcactttct ttagcattag ctcttgccga tgtgatccag acacaagctg gtggtgtagc
     8161 aatcgatgca ttgtttattg atgaaggatt tgggtcatta gatgaagaag ctttggaaat
     8221 ggcaatggaa gctttagaaa cgatcgaaag tgaaggaaga atgatcggca tcattagtca
     8281 tgtaagagaa ttgaaagaac gagtattaca acaaataaga attgatacag aaggtagcgg
     8341 acaaagcaaa atacgctatc aacttggata aaaagggaga ttggtaacta tgaaatggag
     8401 tattccagaa aaagtcattg cacgtggacg tcaatacttg caagaaggcc gagtgttatc
     8461 ggttgtccct gaccaagaag aaaacgtgtg gcatgcagaa gtcttgggca gtgaattgta
     8521 tatggttgat ttggatggta cagcaaaaga gatagattac tgccaatgtc cctattggga
     8581 ggaacataaa tattgtaagc atacagttgc tgtggaactt tatttacggt cgaaaaatct
     8641 atctcgtatc atgaaaaaag accagccaat gctagaaccg gtaaaagcaa caagtgaggg
     8701 agaaatcatt gcaaaaggtt tttctcgtct aaaaacacaa aacaatcctc aagcggtgca
     8761 acctttgatt attgaatacc aagtagaaac gattgagact aatcagtatc acccagagct
     8821 ttctattttg gcactttact tgcgtatcgg ttcattggca tcaccgaaaa aaacatatat
     8881 cgtaaaaaac atctatgatt ttttacaagc ttacacagaa aaagaaactt acactgttaa
     8941 taaacagtac cagtttcgtc tagataaacg ggcgtttcaa aaagaagatc aaaaaatact
     9001 cacgcatctt gcaggaagtg ctcagacgca tcaattatta ggtacgaacg gcttacaagt
     9061 caaaggaaaa ctagataaaa gatatctgct tctcccagta gaacaagccc gcttcctgtt
     9121 agagcagatg aatcagacta cacgtttgca tctgcagata aatgaacaaa acgatcaagg
     9181 aatacaattt tccgatcaaa acaaaccttt atcattcaaa gtggaaaaat ttggagaaga
     9241 ttatttgctg caagcattga atgattttga ttttttcttt atgcattatc agtggggagt
     9301 tatccaaggg acattttatt ctctgacgaa atatcaacaa acggtttatc aaacttggaa
     9361 acaattgatt cgccgattgg agaaaccaga agtagtgttc aagaaaaaag aattaccgtc
     9421 tttgtttaaa gagattatcc ctctgctgtc agagatcggc gacgtagcta ttgcccctgc
     9481 agtagaagag gaagtagcag atatccccgt cgaatttatt ttctttttcc gaaaagcaaa
     9541 aggaaaaatc caagctcgag tcgatttcgt ctatggcgaa gtcatctatt cgactgaccc
     9601 gaagcatgag gtctcgacag aacaggcttt tcaggtgtta cgtgacacag tagaagagaa
     9661 acgagtactt gatctattca gaatgtatcg ctaccagaaa aatgaaactg gttatgaacg
     9721 tccattgcca agcggggaag aactatatgc ctttttccgc acagaactat ctgtcttccg
     9781 tcagtttggt gaagtcagac ttggaagaaa attgcgagag ttgtatttag atgcgcataa
     9841 acatcaaccg aaaatcgaag taaccgagac cggttcatgg ctcgatattc gattcgatgt
     9901 gacagggata gaggagcaag aaatcgatca tgtcctgcaa agcttgctga gaaatgatgc
     9961 tttttataca ttagaaaatg gtcaggttct ttcttttgat tcagaagaat ttcaacaaac
    10021 aagccaagtg ttgcaacaat tacgggaatc gatacgtaca gaagaaggaa cgatccatgt
    10081 acctaaaaat caaggattga tcattcaaaa tcaattggaa aaaagcaatg ctacttttag
    10141 tgaatcgttc caaacgatgg tacaagatct cattcatcca gaaagatacc aggcacagct
    10201 tcccaaagga ttgaatgcaa cgatgagaga ttatcaaaag caaggttttc gatggttgaa
    10261 gatgttaggt cattatcagt ttggcggtat tttagccgat gaaatgggac ttgggaaaac
    10321 actacagaca attgcctttt tactttcgga aaaagaagaa cggaaaagct tctctgcttt
    10381 gatcgtagcg cctgcgagct taatttacaa ctggcaggca gaggtgagaa aattcgcccc
    10441 ttctttaagt atccaagtaa tcaatgggaa taaaaaagaa cgtgaagaat tactggctaa
    10501 agacacagat atccgagtga cttcttatgc cagcttaaga caggatctag ctaattatca
    10561 gtcgcaaaaa attgattatt tgattcttga tgaggcacaa atggtcaaaa atagcagtac
    10621 gaaaactgca caagcattga gagaattagc tgtacctcag cggtttgcac tgagtgggac
    10681 accaatcgag aataatttag aagaattgtg gtcattgttt gcaacgatta tgccaggatt
    10741 tttcccgact aaaacaaaat tcagggaact tgccgcagaa gaaattgcgc aaatgattcg
    10801 accgtttatt ttacggcgag ataaacaaac tgtgttgaaa gacttgccgg aaaaaacaga
    10861 gatgaatcta tattctgcac ttacagaaga acaaaaaact gtttatttag cttacttgcg
    10921 tcaaatgcgt gaagaaatca catcaatgga ttctgaagca ttcaagaaaa accggatcgg
    10981 gatacttgct ggtctgacaa gactgcgaca aatttgctgc gatcctcgtc tgtttattga
    11041 agattaccaa ggcggttccg gcaagctcga acaagtaaaa gatctactgg tagctgccaa
    11101 agagaacaaa cgaagagttt tgctgttttc tcaatttaca gggatgctga ctatcttgca
    11161 agaagagtta gccgagctag ggatctcgac attttattta agaggcagta cgaaaccaca
    11221 agatcggtta agtatggtag acgcatttaa tgctggcgaa aaagatgttt ttctgatttc
    11281 cttaaaggct gggggaactg gattgaatct cacgggagca gatacggtca tcttgtatga
    11341 cctttggtgg aatcctgcca ttgaagaaca agctgctgga cgtgcacatc ggatcggaca
    11401 aaaaaatgtg gtagaagtgt ggcgtatgat ctctgaagga acgattgagg aacgcatgga
    11461 ttcactccag caagaaaaac gcgaactgtt ccaaaaagtg atccaaggta atgaagaaca
    11521 gttgacgaaa ctgactgaag aagacatccg catgatttta agtgtaggag aaatcgagga
    11581 gtaagagact cgaaaaagcg ttcagtaatg ggtaagaaag cctttctaaa gaagcgattg
    11641 tttatttgat ttaaaaaata gcaaggaggc tgggattcca ttttatccca gcttccttgc
    11701 tatcattttt ttatttctat ttttaaaggt tatacaaaga ttgtcttcat tgtctctaac
    11761 agctgatcaa aagaagaaat ctcgatatcg caaattggag tctgttcaat tttgcgttct
    11821 cgatggttga accaaagcgc ttgccagtta gcactttttg cacctagaac atcattgtcg
    11881 taattatcgc caacgtataa ggtctcttct ggaagcatat gaaattcttt ctcagctagc
    11941 tgaaaaatct ctttttctgg tttttggaaa cctgttgctt gagaaatgag catattgcgg
    12001 gaaggaatcc aattgttcaa ttgaagttgc ttcagttttt ttgtctgatg gtcagtcggc
    12061 ccatttgtga taattcctaa tgggacattc ttttccttca agaaatcgag ggtttttttg
    12121 acctcctcat gcaagcagat attatcaagt tcttcctcgt aaattttttg aaataagagg
    12181 ccatcttctt ccgtaatatg agggtagtct aaatctttta gtgattggct gatccgatgt
    12241 gctcgcatat attctagtgt ccaatctcct gccattactt ttgggaagtt ttcatcacta
    12301 tgatggcgga accggatata tagtggatgc atatctgcat ctgaaacaag cggaacgact
    12361 cttttgaccg cgtttcgaaa tggctgctgc tgatcataca tcgtatcatc aacatcaaac
    12421 acaactgatt taatcaaaat tttacacgcc tttcggtttt cattgatttt ttcacaaatc
    12481 cttgactatt gtaacagaaa aaattgtcta aaaaagctga taaataaagg tttttcttac
    12541 tatatttcta tttccttgac agaataaggt ttttatattt cagttttttt cactaaaaat
    12601 cgtgaaacac gtcaataagt ttgatgaaca aattaatcat tatggtagaa gtcgattgat
    12661 ttattttaat gcaatctctg tggaattttc gaaagattta tttttttaat acagtctcaa
    12721 tataactatt caaacataaa ataacgttat ttgatttatt tgtttatagt aaattttatt
    12781 tagtaatcat tgctttaaaa tactacgctt atataacaga gaaaataagc gttataataa
    12841 agaacagtat tatttaaaat gacagaaaac attactatta aagaaataaa aaacataaaa
    12901 aatcttaaga aatcggtttc atttagcttt tgagataaaa taatagtaca gttttatacg
    12961 ctgtttcata tgtttagaaa atttgaatta gatttgaaaa ctctaatttt taaatgataa
    13021 aaaaagcgag aatgctggtt ttactgtata ttaaccttag ataactttca tttttttaaa
    13081 aaaattatga aaaaaaggta gctatttaaa agttgattat gtataataga aacagatggg
    13141 agattattat gatcttctgt tacaaaaaag tgattcttat cacgaaaagg agtggtgcac
    13201 gttgttaaca ttatatactt ccccaagttg tacttcctgc agaaaggctc gtgcgtggtt
    13261 gcaagaacat cagattccat ttgttgaacg taatattttt tcagaaccat tgaacagttc
    13321 tgaattaaaa gcgattttac aaatgacaga agacggaaca gaagaaatca tctcgacacg
    13381 ttccaaagta ttccaaaaac tgaacatgga tttagatgat ctgccgttac aagaattatt
    13441 ggaacttgtg caaaacaatc ctggattgct tcgccgtcca atcatgattg atgataaacg
    13501 tctgcaagtt ggttttaatg aagatgaaat tcgtcggttc ctaccgcgcg atgtacgaca
    13561 attagaatta cgtcaagcac aattgatggc tggattatag aaggataata cgaaacttgg
    13621 aaaagactat tacaaagata gtttttccaa gtttttttgt ttttacaaaa agtattcttg
    13681 attagatgta taaaaaggta gtagaagatg atgattgcac gaaaaataga gagggaaaat
    13741 tagctgaaaa gtcggctata tagtattcgt ctgccaaaaa tgttatagtt aaataagata
    13801 gcttgaaagg ttgaaaaatc cgctggtttt attaaattcg cttaacagcg agattttttt
    13861 tctttacatt taagctgatt tcgctacaat gaatctatat taaacattgt ggcaaagtga
    13921 ggtgtagcaa aatggaaatg gaacatatta atgaaaatac gatccgtgta ctaattggtc
    13981 atgaagattt agaggaacgg ggcgtttcat ttttggattt acttggcaat cacaaagaaa
    14041 tcgaaaattt cttttatagt attttggaag aagttgatat cgaagaggag ttccgaggaa
    14101 gcgaagctgt cactttccaa gttttgccaa aaggagacgg attagaactg tttatcagta
    14161 aaaatcttcc ggatgaagaa atttctcaat cagaagattc tactgttgat tcagaagatg
    14221 tgagtgactt tcttcgtcag cagattattg gcagcgatcc ggaggaagaa ttatctggaa
    14281 gcgccctaga agaacaggaa agacaagcaa cttttgcttt tgaagatttt gaacaagtga
    14341 tccaacttgc aacagatgtc gaactagagt ctgcttggac tgatttgtat ttattcgaag
    14401 agcgctatta cctagtcgtt cacttctgga tggaaaatct caaccaagcg gatgtagaga
    14461 atcagattgc tcgaattttg gagtttgctg aaaagagcga tcgtacacca gaaacattga
    14521 atgaatatgg acaatgtctg atggcgcgta atgctatcga gcgaacgaaa ttttattttg
    14581 tataaatcag cattatagta agagactgtg acaaaaattg tgtcgcagtc tttttttcgt
    14641 ataaatgtgt tcaaaagctt gcatctgcgg taacaagccc aaccaaacga aaaatattgg
    14701 gaactatttt tgtttagctg ttcttattac ttgatgcaga atagcttttt cacgccctct
    14761 tttttcgtgt aaataaattc ttagacgtaa ataagttcag agggagaaaa atgctgcttg
    14821 caatgaatga atataataag tgctgttttg ctaaacatgc agaaaaagga aagaaatatt
    14881 attgtcgtgg ctgtcgaaaa agagtgattt tgaaaaaggg aaagaaaaaa tgtgctcatt
    14941 ttgcccatca aaaatcagat aactgttcgg tctttagtga aagagaatca aaagagcact
    15001 tacagttaaa ggaatgcttc atggattggc tgggacagtc agtagaacca gtatttttgg
    15061 aagcctattt gccgaggttg cggcaaaggc cggatatttt gttggcgaat ctagcaatag
    15121 aaatccaatg ttctagactg tctcaccaga gatttattga aagaacccaa aattatttga
    15181 ataacagtta ccaagtatgg tggatacttg gtaattcttt tcttggacaa tcgcaattct
    15241 cattgataga aaaaagttgc tgctactata atagaaaaag aggagtgcat tgctggaaag
    15301 ctgatctcaa gaaacaaaag ctttatttgt atcatcatat tacagagact gtatcagggc
    15361 atatttcctt ttgcagtagc tgctggactt tttctagtag ggaccttaaa gaaatattca
    15421 ctagtaacga aattaaaatg aaccaaatga aaaaaataga aaaagtgagt gaagatggga
    15481 agaaatggct gacacgccaa cttattcaca agcaaaagaa tacagtatcc atacaagaac
    15541 aatgctactt gcgtcataaa catcttttgc atctatcatc gtggatctat caaaaaagtc
    15601 ggtttttctt ttatttacaa gaacaggttt ttctttatcg aatgttgtac gaagaagcct
    15661 tggaaaacca gaaagttcct gatttcaact catggctttg ccaaataaaa gaacataaaa
    15721 gggaatggct ttttcctatg attgatgaag agatggtcta tcagcagttt tttaacgaat
    15781 gcatacactt gtcttctttg aaaaaatagt aagtataaaa ataggctagg aatcggtttt
    15841 ctatgtaaaa caagatttag ttatgctaaa attgatggaa gcagacacat gaatgagtag
    15901 aaaagttaga tgctgtgaca tgtggatgtt agactatgat ctattttgat agatagagct
    15961 aagggaagaa aaggagtgga tttcatggaa gtaaagcagt tgccaaaacg agaagaattg
    16021 cctgaaaatt taacttggga cttgaccaag atcttttcaa gcgaccaaga gtttgatgag
    16081 aaatatttgg aattatcaga agagttaaaa caatctgaaa aacacaaagg aacacttgat
    16141 caaggcgctt ctcaattttt aaatgcgatt gaattcgtat tgagggttta tcgccaaact
    16201 gaagtcattt atgtatatgc gcaccttaaa aacgatcaag acactggaaa tacagattac
    16261 caagcgcttt atgcaagagc aagcagtctg ttttcgaaag ttagtgaagc cgtttcctgg
    16321 tttgaaccag aaatattgca attgtcagat gaccagattt ggcaatattt caaagaagaa
    16381 ccaaaattgg aagtctatcg ccattatatc cagcaaatag tagataatcg agcccatgtc
    16441 ttatctgctg agcaggaatc tcttcttgct ggagcaggtg aaatctttga tgcttcaagt
    16501 gatacatttg ctgttttgaa taatgcagat ctagtttttc caacgattga aggagaaaat
    16561 ggtgaaatag tccaattatc tcatggcgtg tatggtcagt tgctagaaag cacggatcga
    16621 agggtgcgcg aagcagcatt taaggggttg tacagtgttt acgaacaatt tagaaataca
    16681 tttgcttcta ctttaggcac acatataaaa ggacataatt ttaaagcgaa agtccgtaat
    16741 tacagctctg ccagagaagc gtctttgagc aataatcata ttcctgaaag tgtatacgat
    16801 actttggtag acgtggtaaa caagcatttg cctttgttac atcgatacat ggaattacgg
    16861 aaacgtttat tagaagtgga aaaactgcac atgtatgatc tttatacacc ggtcttaggg
    16921 gaagctccaa ttacctttac gtacgaagaa gcaaaagaaa aagctttaga agcactgaaa
    16981 ccaatgggtg aagaatacat ggccatcgta gaaaaagcat tctctgaacg ttggatcgat
    17041 gttgtcgaaa ataaagggaa acgaagcggt gcttattctt cgggaagcta tgacacaaat
    17101 ccatatattt tattgaattg gcatgatacg ctggatcagc tatttacgct tgtccacgaa
    17161 atgggacata gtgttcatag ttatttcact cgttcgaacc agccttatgt gtacggcgac
    17221 tactccatct ttttagcaga aattgcttcg acaacgaatg aaaatatcct aacggagtat
    17281 ttattggaaa cagaaaaaga ccctcgtgta cgggcttatg tactcaacca ttacttggat
    17341 gggtttaaag gaacagtttt ccgccagaca caattcgctg aattcgagca tttcatgcat
    17401 acggaagatg aaaaaggtgt gccattgact agtgaatacc taagtgatag ttatggtaaa
    17461 ttgaatgcaa aatattatgg tccagcagtc gaagaagacc cagaaattaa attcgaatgg
    17521 tcacggatac cgcattttta ttataattac tatgttttcc aatactcgac tggcttttct
    17581 gctgcttcag cactggcgaa gaaaatacta aaccaggaac cagaggcact agagaactac
    17641 ttggcttacc taaaagcagg taacagcgat tatcctgtgg aagtaatgaa aaaagcagga
    17701 gttgatatga cacaggctgc atatattgaa gatgcaatgt cgatgtttga acaacgtcta
    17761 aatgaattag aagaattgat cgatcgttta taaggctttc tatttttgat tttctcgaat
    17821 agaaacgaaa aaaatacgtc ggctctcttg taagggagtc gacgtatttt tt
//
LOCUS       DAFEIE010000051        17700 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFEIE010000051
VERSION     DAFEIE010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.053"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            99..2426
                     /locus_tag="LP345_001987"
     CDS             99..2426
                     /locus_tag="LP345_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1760762.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2552..2881
                     /locus_tag="LP345_001988"
     CDS             2552..2881
                     /locus_tag="LP345_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL1760763.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            2921..3925
                     /locus_tag="LP345_001989"
     CDS             2921..3925
                     /locus_tag="LP345_001989"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1760764.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3922..5351
                     /locus_tag="LP345_001990"
                     /pseudo
     CDS             3922..5351
                     /locus_tag="LP345_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            5557..6729
                     /locus_tag="LP345_001991"
     CDS             5557..6729
                     /locus_tag="LP345_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1760765.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6891..7346)
                     /locus_tag="LP345_001992"
     CDS             complement(6891..7346)
                     /locus_tag="LP345_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760766.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            7935..8357
                     /locus_tag="LP345_001993"
     CDS             7935..8357
                     /locus_tag="LP345_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760767.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(8523..9716)
                     /locus_tag="LP345_001994"
     CDS             complement(8523..9716)
                     /locus_tag="LP345_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1760768.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            9940..10317
                     /locus_tag="LP345_001995"
     CDS             9940..10317
                     /locus_tag="LP345_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1760769.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            10305..10643
                     /locus_tag="LP345_001996"
     CDS             10305..10643
                     /locus_tag="LP345_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1760770.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            10777..11220
                     /locus_tag="LP345_001997"
     CDS             10777..11220
                     /locus_tag="LP345_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBL1760771.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            11482..12297
                     /locus_tag="LP345_001998"
     CDS             11482..12297
                     /locus_tag="LP345_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1760772.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            12307..12969
                     /locus_tag="LP345_001999"
     CDS             12307..12969
                     /locus_tag="LP345_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL1760773.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            13174..14838
                     /gene="alsS"
                     /locus_tag="LP345_002000"
     CDS             13174..14838
                     /gene="alsS"
                     /locus_tag="LP345_002000"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBL1760774.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            14851..15561
                     /gene="budA"
                     /locus_tag="LP345_002001"
     CDS             14851..15561
                     /gene="budA"
                     /locus_tag="LP345_002001"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBL1760775.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            15691..16188
                     /locus_tag="LP345_002002"
     CDS             15691..16188
                     /locus_tag="LP345_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBL1760776.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            16373..16633
                     /locus_tag="LP345_002003"
     CDS             16373..16633
                     /locus_tag="LP345_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760777.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(16995..17234)
                     /locus_tag="LP345_002004"
     CDS             complement(16995..17234)
                     /locus_tag="LP345_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760778.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(17571..>17700)
                     /locus_tag="LP345_002005"
     CDS             complement(17571..>17700)
                     /locus_tag="LP345_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1760779.1"
                     /translation="QNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT         5999 a         3071 c         3507 g         5123 t
ORIGIN      
        1 aaaaagcccc aaactttcta tacatcaata aaataataaa aattaaattt agaataacgt
       61 gtaaaggatt atttgatgat tttttattga gaggagggat gaaaatgatt aagaaaactc
      121 aaaataaaat ccaacgtata tgtcaaaaac attttgtttc tagactcaaa gctgtatcta
      181 aaagaaaata cttacatccc attatgattt cgatcatctt gatttttact ttcttaggga
      241 gcttatcaag tatttatgta aacgtttata cagaaacgtc aaattttgct aaccaaacga
      301 cagaggagac aaatagtcca ccctattctg aaatacagtc catagaaagc accaatcagt
      361 ctagcaacaa cgagacaacc tcaaccacat cctcgactca actgattgat ccgacagaaa
      421 aagaaatcac agcagcaaaa gcagcagggg agaaagctta ttcagaaaca ggtagaagcc
      481 agacatttag tactgttgcg gccactgcga atttcaacgg acataccata ccagatggat
      541 atacagtgat atatgccaaa gatggagtca ttgttgcggt taacggatcg atgagtgcgg
      601 ataaaactgc gttacaaggc gtaaccaaag caatcgcttt tattgataac cgtccagata
      661 tccataatct gtttattggc tccacagtaa atggtactac tatcacattc ccaaaaagta
      721 tctatatggg ggtggctacc gctggaaata cgatcgattc agttacaccc aatgcggata
      781 aaagttattc ttttacaccc tcaacatggg gagggcttcc tgccggagga ggtatgagta
      841 ctttttcaat cggtatacag ttagcaaatg atattccatt cacggggtac tcgatcaaaa
      901 atgggcagat cgttgatggt aagggaaatg tttcaaattt tccaacctat caagcagcaa
      961 cggttcaggt caatgcgaat cggacaggaa ctttttctta tacagtcaat ggtggagcag
     1021 caaaaatcgg aacgtacggg actacattat ctggaatcca tgtgggtgac aaagtggtta
     1081 tcactccaac agcagtaacg ggctattctt ttgcacaaac aaacggttct ttcacagccc
     1141 tagaaagtaa cgtcgatacg gtgacctata caggcaaaca aacaccaatc actattaagt
     1201 atcaagacta ttttggacag atgattgctc cttctaaaat aatgaatctt acttacggaa
     1261 gtgctgcaca agacctgacg actaatacgc ctactatcaa cggatatacc tttacagctg
     1321 tttcagcgac agaaacaaag aaccaatcag caatgagtgt tttagctagt ttagatacaa
     1381 atggaaatgt aatcgtaaag gacgcaaatg gaaaacagat ttctgaagtc atcctatatt
     1441 ataagacaaa tgcaacagta tcaatcaatg caaatggcag taagtactat gatggtcttt
     1501 ctgttgtacc gatcgttaaa tatgccttta atgataaaac agaatcaaca tcccttttaa
     1561 acaatgatct cagtattgat caaatcacat ggaatccaac tgatttcaaa gcgatgaatg
     1621 aaaagggagt tgaagtaact gcgcctactg aaattggaac ctatacgtct tggcaattga
     1681 caaaaagcgg actagctaaa ctagctgcca gaacaaacta tttatttact atcgtgcaga
     1741 catctgatgt ctatacgatt aagcaaatca gcggtgcggt agagctcagt ggcagtaaga
     1801 catatgatgg aaaagcaggt gtcccgtcaa tccatgtcaa gctagcagag ggtgtcacta
     1861 gttcgcttac tccagtacaa gtggcactta gcagtatgga ttacacagca gatgcacaat
     1921 cagcaaaaaa tatggttaat gctggcagct atacaattaa actaacgaat agcggaatag
     1981 acaaagtcaa agcagcaaat cccaagttgt catttactga tatagccaac acatcaggaa
     2041 cttataccat ctataaagct aacgcagtga ttactgtcga tgacgctgcc tttaattatg
     2101 atgcccaaag tcactcgatt tcggttggaa atctccacgt taccggtgtt gtcttaggcg
     2161 aatcattgga ttatacccta acagttaaca gccggacaga tattggatca caaatagtaa
     2221 cgattagttt aggcgaagga agtgtaaaca ataattatac gattatcgca acagataccg
     2281 ctaagttgac gatcaatccg actctcttgc ttccttcgac aggtgggata ggtctactgc
     2341 cctttgtctt tttaggactg atctttattt tttctggctt cttttatttt atccatcgta
     2401 agaaaaaagc aggtgaacag cgatgaaaaa aacaaaaaat gtacgtgtgg atatatttgc
     2461 tgttctcttt tttatcctac tggtcttttt tataggttct ccgactgtgt cagctagaga
     2521 atcacctatt acatttactt tgcataatcg aatgttcgaa agcgataaga tgccaagtat
     2581 cagtcaaaac gacggaataa atatcccgga taactttcaa ggagtaaaag ggttgaacgg
     2641 cgttactttc gctatatatg atgtctcgga tgaattttac aagctgcggt cagaaggaag
     2701 tagtgtggaa gacgcacaaa gaaaactagc acaaaaaagt gatagtgaaa aaatactggc
     2761 agaaaatgtg acaaaaacag tagacgagga agagggcatt gcttctttta gtgcatcgga
     2821 caaagatgag caaggtcgtg acgctgttta ccgatttgcg gaaataaaga cttcagatta
     2881 agtaaaagaa aaatcagcac catttgtcgt tgtgcttcct gtgacagatt catctaatca
     2941 taaattgacg accatccact tgtatccaaa gagcgaacaa aaaatacctg ctgcactcac
     3001 attaacaaaa acagtagaga ataagcagac agattttgca gatggggata aagttcctta
     3061 tctcatcacc gtaacaattc ctgagaacat caacgagata ggaacctata cgatcaaaga
     3121 tacagctgat cctcagttat ggctagaacc agaaacgatc gattttttga ttggtggaga
     3181 caagattcat acatttcaca cacaaaaaac aaaacatggt tttgtcttat cagattctgg
     3241 aaaagatctt agttcgtttg ctgggaaaaa attaacgatc cgttaccaaa tgacattgaa
     3301 agaaaacagt gaaaaaacga catttgataa cgatgtacgt ttgacgactg acaatcaaac
     3361 agtagaaaca catcttgcca tccaaacagg aggcaaacaa tttgtcaaag tggatcggca
     3421 aacgaaacaa aaactagcag atgctcaatt tctagtcaaa aaaaatgacc aatacttagc
     3481 gcaagaaaac gggataaatc attgggtagc caaagatgat tcaagagcaa cgatttttac
     3541 ttccagtaaa gatggaacat tttctgtcca tggattgtct tttggaagtt acgaactagt
     3601 ggagattaaa ccgcctaaag gatatatatt gagtcaatca accattctct ttgaagttga
     3661 aaaaggcagt tatgatccgc ttcatcctat accattggaa atcatcaacg aaccaaaagc
     3721 aaatccgacg aataatggaa aaacgccagt tcagatgcag acaaatggtc catcaaatga
     3781 aaaaaatgga ggaagctttc caaaaacaag cgaagagatg cttggaggtt tctcaatttt
     3841 agggttgttg ctagtccttt caacagggac agcttggttt tataaaaaac aacaaaaagg
     3901 aaacaatagg agggaaataa aatgaaaaac atcaaaacaa aaatatggac gtttttagga
     3961 actgctatca tgctgcttcc tttcgttctc ggcctaggaa ctgcagaggt ttctaggccg
     4021 tatcacctac accagaaaat gttacggtta atttgcataa attgaaattc acttcagcac
     4081 cagaaaatca aataaacaac ggaacggaat tgacatttcc gaatagcgaa ccgttgaacg
     4141 gcgttgaatt caacgtatat gacatcactg ctacgtacta tccaagtaaa gacacagcag
     4201 ttccagcaga cgctacaccc ttcgcaagtg taacgacttc tggtgaagga ttagctaacc
     4261 tgactcttcc aggtaaatct gatgggaaag atgctgtata cgtctttgta gaaacaccaa
     4321 agcccggtgt cgaaacgtcg ccaaatatcg tgttaagctt acccttttat aacccgaatt
     4381 catcagaccc tgacaaacct ttagacacga ttcacctata tgctaaaaat gtcatcaaag
     4441 aaagcaatat caaaatccag aaagctggga acttttcagg ggtagataag ttagcagggg
     4501 cgcaattcca gatcaaaaat tcagagaatc aattcgtgac cggttttgat gaaaacactg
     4561 gtgtcgctct ctatgatcct gctgagtcag cgttgacatt cacaactgat actgaaggat
     4621 ccatcagtgt caatggatta atagacggca attatacttt agttgaaaca aaagcaccag
     4681 atggttatca attaaccaat ccacaaaaag aaactacttt tatagtaaaa aacggaaaat
     4741 tgcaacaaac aaccggtatc atccatggcg cagatgaagc caatcttggg aatccaaacg
     4801 gtgtagtcaa tcgggaaaat acaactacgg ataacacgat tactgtagaa aatgtccaaa
     4861 actacggtga tttccacttc atcaaacaag atgtgaacac gcaagaaaaa ttagccgatg
     4921 cagaattttc tattctaaga gcaaaagatc caactgttaa attaatgaaa aaaatagcaa
     4981 atcttgcctc aggagaatac ccatatgctt ggtcagatga agtcacaggt tctgactggg
     5041 aagaagtgaa attgatttct gattcagaag ggaaattttc aatcgaaggg ctgaaacaag
     5101 gggcatactg ccttcaagaa acaaaagcac cagaaggcta cgcattacct aagaatgaag
     5161 ctgcgtacac tgaatttaca gtagatgatg atccaacaac ttctgatgaa acaacgatcg
     5221 ataaccaacc taaaggaatc ttgccttcaa ctggtggtat ggggatcatc gtattcatct
     5281 tggtaggtac tgctttagtt ggaggagcag tgatctactt caaaaaacgc catcaagaaa
     5341 cagaagctta aactattgga aacaaaaatc atacgataaa taaacgatgg tgattcaaat
     5401 ggggagaaag gttgtgacaa gtggtcggtc tcttggtatt cgctcaacaa acggcaaaat
     5461 aggaggaact attttgccgt ttgttgagcg aatactcagg tcaaggcgct gatttcacaa
     5521 cctcttcata tacatattag aaaataggtg gacatgatga ataaaagcag aataagaata
     5581 ctggacatct tcatggcaat cattttagtc gttgggatcg ggatcttttc ttatcctttt
     5641 gtagaagatt cactgaatga ttttcttgcc cagcaaatga tcatccatta tcaaaagcaa
     5701 gcatcgaata agaattcaga ggaaataaaa aaacagcagg aaaaaatgac aaagaaaaac
     5761 caacagttgg cagagcaaaa cgtatcacca gggataggca gtttcaacca agcagttgat
     5821 gcaaaagcat taaaagattt acctagtaat gcctttttta tggaacatat gcttggagtc
     5881 atcgaaatcc caaaaatcaa tgtcagctta cctatattcg atcagacaac ggaaatattt
     5941 ttgcaaaaag gaacgtcatt attggaagaa agttcttatc cgactggcgg gaaaaacacc
     6001 catgccgttc tttctgggca tcgtggactc ccagaagcaa aattatttac agatttgcct
     6061 aagttgaaaa aaggagacca gtttttcatc cagatcaatg gaaagacatt ggcgtatcaa
     6121 gtagaaaaaa tccaagtggt cttacctgat gaagtagatt ctttgggtat ccaaaaaggc
     6181 agagatctcg tgactttgct tacctgtact ccttatatgg tcaatacaca tcgactgctt
     6241 gtgacggggc atcgtattcc ttatcaagca aaagaggcaa aaaaagcgat ccaaggaatt
     6301 gatcaatgga aaaaatggaa attttttatt tggtttatcg gtatactact tggatcaatc
     6361 ggcttagttt ggctactcat cgcttattta gattctttgg ccatcgctaa gcgaaactat
     6421 cctttatctt tttatgtaaa gaacacaaac ggacgaccaa tcgaaggaat ggtcttttct
     6481 gtaaaaacgc tcaacggcaa acactatatt actagagaaa aagttccatt tgtgaaagct
     6541 tctgatgaat acggactagt gagattttct gatttaaaag gcaggaacta tcgcttgcaa
     6601 catgaggagc tcctgcttaa aatccatgta aaacataaac attcgaaaca gttttcaatg
     6661 aaattgaaaa aaggaagata taaactgcga aaagaaaaag aggtgtacta tttgattgag
     6721 aaagaatgaa tgaagatgtc caaaaaagca gagggaacag actaaatgaa aaaagagaga
     6781 agctgacgaa atggacgtgt aaactgctat ttttggttta ctatctggaa cgccagcttc
     6841 tattttttta tgtttcagaa gaattttatt attatagtat aacttttgaa ttagtttcca
     6901 taacatttgg agcaaggggt taaaccacga gcttgagctt cgcttaaagt ggcaggggta
     6961 tacgtaccat ttccacattt atgtgtatgg tattttgaac cggtcggtgt gacatagaca
     7021 gtttgttcat tattttgctc aggagctgcg gcttgtgcct gctgagaggc ctgttcagct
     7081 gctgcttgct gtcgcgcctg ttctgcttgt tgctgtgcga ttgcttcttg ttgcgcttgt
     7141 tctgcttgtt gtcgtgcaat ttcttcttgc tttttccgtt cttcttctgc ttcttttgct
     7201 ttgattgtgg aatcaattgc agcaagacgg cttgtcaact cttgtttgtt ttcaggtagc
     7261 gcttggatag ctgctgaagc agttgcatag ttttcttttg taggatttgc ttcagcttgt
     7321 gacaaagcag attccgcttc tgtcactttt ttttctagtg cagctttttc cgctttttgt
     7381 ttctcttctt cttttttctt ttcaatttgt tcttgttctt tcgatgaatc tgccgtactt
     7441 tcggagatcg tggtactgct gctggaagcc tgagctgaac ttgtgctttg agtagtagac
     7501 gtagtagcac cacacccact caacaaactt cctgcgacca aaaacaatgc aactaatttt
     7561 ttcactaaat ttcctcctta agtaaaaaac aaccgttttc aataaatgtc cttttcaatt
     7621 gtttacttac ttgttataat aattgtgtta tgaatagtga ttgaggaaac ttaatctaat
     7681 cccgttttga tacacgggat tttttgctat agttctgtta ttaagtatgc aataataaaa
     7741 tatgtacgtt attttattat tagattattg acatttatat aataaacgat taaatgattc
     7801 atatcaatag aatacttagg aaaaaaagag aaataataac aggtttatgc actattgacg
     7861 gtgtgacaat atgatatttg tatccgtttt tttcttgtat gtagtatagt aaagtagata
     7921 caggaggaga aaatatgcag acttttttaa caaaagtttc tcaaaagaaa attaaaatga
     7981 ttcatttact gcttgaaaca gaacgttggt gttcaataga agaactacaa aacgaattga
     8041 aggtatcaag taagtctatc ttgaattatc taacagattt agaagaattg ttccaaaaat
     8101 atcctgataa ggtcattttg aagaatgaga ataatcggcg cttttctatg gaaaagcagg
     8161 agaacttccc aatctacatt atttatcttc atttctacag aaaatcatat aattatcatt
     8221 tgattgaatt catgtatcaa catcctgaga aaaatttgga agattatgca gacgctcaat
     8281 atacgagtgt atccacagtt tttcgttatg ctaagttatt agtaaagtac tttgaaatga
     8341 cggacgtcaa agaatagtag ccgccagata gaaggaaatt agcagttgaa aaagctgccc
     8401 tgcatcaagt aatacgacca gccaaacgga aacagtgtct catgtttttg atttggctgg
     8461 tcttattacc gcagatgcaa gcttttgcca cacctctttc ttgtcattta cagactcaac
     8521 tatcaatgct gcaagctttc ccttaatgct gtaacaccag taagagttgt caagaccagc
     8581 agactgacta ggtaaatacc gctcaaaaac aagattacgg cagttaaact ataatgatcc
     8641 atcaagaaac cgatgacgat agaagaaaaa ccaccaacag ctcgtccaag gttcataatg
     8701 aaattattcg ccgtcgcgcg gatttctgtt ggatacaaac tactaatcac tgcgccatat
     8761 ccaccataca tgccattgat aaagtagccg actatcacag cggctgctac caaactccac
     8821 tggctatggg ctaacacaag tagatagaca gataaggatg aacaaattaa aaacaaagaa
     8881 aaggctagtt taggccccaa tttatccatg attatgccaa aagtcatcat ccccaaagac
     8941 atgcctaaaa tagtactgac catccacaat gaagacccag aaaccgaaag ccctaatcga
     9001 ttttgcataa ttgaaggcag ccaattcatt aacccaaaat agccggcaat ttggacagtt
     9061 accatgatac taaggccaca tgtttgccaa gcaagatgtt ttgattcaaa cagtctgcta
     9121 agtttggttt tcttttcggc agattgtaca gatttgaatt cctttggttc agtcaagccg
     9181 cgacgaatga acaagaccat caacaccggc agtacaccta cgacatacaa catcttccaa
     9241 ccaaacgttg gaatgatcac agcagctaaa atcgcagcca aagccgcacc gacctgcgca
     9301 ccaataccag caaccgaaga agctcgtcca atttgttttt ttgaaaaact ttcggaaatc
     9361 aaggacatac acgccccgta ttctcctccc gctcctacac ctgcgataaa gcgaaagaga
     9421 taaaccaagt agatgtttga agcaaaatac atcaataaag aagcaatcga aaacagaagg
     9481 accgtttgag aaaatacttt cacacgtcca tatttatcag ctatgatgcc aaaaaaaata
     9541 cctccaatga gcatccccaa attagtgatc gttgaaatga aacccgcttg cgtaccacta
     9601 atatgaaaag aagtaatcat tgaagataat gaaaaagcta aaaacataat atccatattc
     9661 tctaaagcaa ttcccgccga tgtcgataat aataactttc gctgatacgt tgtcattttt
     9721 ataccccttt tcctaaaatt tccctaaatt gttaaaagta tatccaaaaa agaataaaaa
     9781 aacaagactt ttttatttga aataatacac aaacaaccga tatagataat ccagcttagt
     9841 tttaatagaa atgagtattg acttggagta cacttaaagt tgtagaataa ataaaataca
     9901 taagtaaagt ggcaagaaat taagagaaag agtgatcaga tgaatatcaa acaagtcagt
     9961 gaagaaaagg gcatttcggc cgatacattg cgctattatg aacgaatcgg gttgattcca
    10021 ccagttaatc ggacaaaagg cggaatccgt gattatacag aagaagacct aaaatgggtc
    10081 gactttacga tctgtatgcg aaatgccgga ttatcgatcg agtctttgat tgaatatatt
    10141 cgcctatcta gcgaaggaga agcaactgta tttgagcggc gtaagctttt gattgaagaa
    10201 agtgaacttt tgacgaaaaa aattgctgaa atgcaagaat gtttggaacg tttacaagga
    10261 aaaatcaaga aatatgatcg tgtgttatct agaaataaaa tggaatgtat caagtaaaaa
    10321 aatcaaggag catcgctatg gagttacgct tactaaaata tttttggaca attgcagaag
    10381 aaggaacaat ctctcaagcc gcagaagttc tacatcttac acaaccaacc ttaagccgac
    10441 aactgaagga gttagaagag gaactaggaa cagaactgtt tgtacgcgaa aaccgcaaaa
    10501 tgatcttgac agaagcaggt tattttctaa aaaagccgag cagaagaaat tttagattta
    10561 acgaatcaaa ccactcaaga attcgagaac agaaaaaaac aattattcag cggccgattt
    10621 acgatcggct gtgtggaagc tgataattcg aatacattgg cactattact agaaaagttg
    10681 atccgtgatt atcccagcgt tcaatttcat atccacagcg gaacaagtga tgatatcacg
    10741 gagtgactag aaaaaagcct gttagattta gcgattttgc tagatccagt agatacagag
    10801 aaatacgaaa cgattttgtt accaagaaag gaaaaatggg gattgctcat tttagaaaat
    10861 tctgttttag caaaaaaaga cgtgataaca aaagaagact ttgcgaatgt acctcttttg
    10921 atctcaaagc gtccagaaat acagcgaatg tttgctgact ggttaggcat aaaaaaggag
    10981 cagttgctga tcacaggaac gtacaatttg attttcaatg tatttgcgct aattgagaat
    11041 caggtaggtg ctgctttagt catagaaggt gctgtaagtc atctttcaaa gcgagtgaca
    11101 ttcgttccgc ttgacccaat gattgaaacg aactgcatgc tagtctggaa aaagaatcgg
    11161 attttatcac ctgtagtcaa tgaattgatt caccgtttca aagaagcttt tgaacagtaa
    11221 taagtatctc taatcgaaga aatttcaata caaaagcgag acgtatgaca gtcttgcttt
    11281 tgtatttttt catttttaaa tcaaaaaaaa taaagagatt tacataactt gttaaataag
    11341 cgcttacaaa cataagaaga acggaaatga atcagctata ataaccgttg ttctggattg
    11401 taatcattac aaagaaatga agattataac tttggaggtg ttcgaaatga aagaaaaaaa
    11461 gcaaaaattc gttcaaaaaa catgcccttt attcaatggt tgggtatgat tctgctgatt
    11521 gtattagctt tattgacgat cattcctttt ttatggatgg tttctgcttc attcaaagca
    11581 aataatgaag tgttcacgat tccgattcaa tggatcccta aaacttggca tttagagaat
    11641 tatctggtta tttggtctcg tattccttta gtgacatttt ttaagaatac agctttttta
    11701 agcgttgtga tcacgttgat tcagttgttt acttctagtt ttgctgctta cgggttttct
    11761 aaactaaatt ttaaagggcg cgatatttta tttttagcat atatcggcac gattgctgtc
    11821 ccttggcagt cttatatgat cccgcagttc attatgatga gaaaagtggg tttaacatat
    11881 acgttgtggt cgttggtgct attacaagcg ttcaatgctt ttggtgtgtt cttgttgaag
    11941 caatactaca gtagtatccc agattcttta tgtgagagtg cgcggatcga tggcttatca
    12001 gagtggggaa tctatcgcaa gatcatttta cctcttacaa aaccggcgat tgccagtttg
    12061 acgatcatca cattcgttaa tacatggaac gattatatgg ggccattcat ttatttgtct
    12121 tctacggaaa ataaaacaat ccagttaggg ttgaaaatgt ttattgggct atttgatgca
    12181 gagtacgcat taatcatggc tgcctcagtt gtttctgttc ttcctgttgc ttttatattt
    12241 ttagcgatgc aaaaatattt tgtagaaggg atcgcttcat caggaatgaa ggaataggag
    12301 gtgattatga aagagcagcg ttttgacaaa aatgtttata tggaattctt ttattggttg
    12361 tatcaatcat tggcaagtag cctttgtttt tggtgtgtca atatcttgta tatagcagct
    12421 gcgttccttt tgtcgataga tggaaggaat gtcttttcct ttattttttc tttacttttt
    12481 attggtccag gttgcatcgt gatgataggt atgacagaag aattagcaaa agaaaaaagt
    12541 ttttcaccag tacgtttgtt cataaagacg tttcgccaat tttggctaaa gggatttttt
    12601 tattggctat ttgcttggat agttagtgtg ataatgattt ttgattgttt cttttttata
    12661 cgtttttctt atggaaaatg gttgattccg ttgtttgttt tacttgcttg tttatcagtt
    12721 tcctttagca tcaactactg gtattttcag gtgagaaatc cagcgtcgaa accaaatcaa
    12781 gttctacgga tagcgttcta ctatacgttg aaaaaatggt atgtgagttt actagatttt
    12841 ttactattga caagtttgtt tctcttcttt ttcgtaaagc cccaatggtg tattctacta
    12901 ggtccttcta tcgtatttgg tttgatttac ttcaacaatc gtaaattgat gagaactatg
    12961 gatctgtaga ctttataaat tgaaactttc aattaagaat gacagttttt atgtaaaaac
    13021 tgtcattctt tttcattttt tgaaacatat ggctaaacaa atgaaataaa acgtgctata
    13081 cttttgaatg aaacaggttt agaaactgta tcaattattt gtgattattt ctaactaata
    13141 attaaaaata aagcataaaa aggacgatgt tcaatggacg aaaaaatgaa acaaggttcg
    13201 aaatctgtag tagaaagttt gattaatcat catgttgatt atgtattcgg tataccaggt
    13261 gcaaaaatcg atggtgtatt taatgaatta gaggatcaag gtcctgaatt aatcgtgact
    13321 cgtcacgaac aaaatgctgc atttatggca caagcaatcg gacgtattac aggagagcca
    13381 ggagtagtta tcgcaacaag tggtcctggt gctagtaact tagctacagg tttggtaaca
    13441 gcgacagcag aaggtgaccc agttttagca attgccggac aagtaaaacg aagcgatcta
    13501 ttgaagttga cccatcaaag catggataat gcagcactgt tccagccaat cacaaaatac
    13561 agtgcagaaa tccaagatcc agaaacaatt tcagaagtga ttgccaatgc ttatcgtatg
    13621 gctaagagtt caaaaaaagg cgcgagcttt atcagtatcc cgcaagatgt agtggatgca
    13681 cctgtccaag ggaatgtcat caagccattg agcgatccta aattaggttc tgcttctgca
    13741 gatgatatcc gttacctagc tgaacgcatt agagaagcaa aactaccggt actattagta
    13801 ggtatgcgag gatcaagtga aaaagaaacg ttagccatca ggcaattagt tggaaagaca
    13861 gcattgcctg ttgtagagac attccaagca gctggagtga tctcacgtga attagaagcg
    13921 catttctttg gtcgtgtggg tttatttaga aaccaaccag gagatatgct tttgaaacga
    13981 agtgatctag ttattgctat tggctatgat ccaatcgaat atgaagcaag aaactggaat
    14041 gcggaaaaag atgcgcggat cattgtgatc gatgaagcgc cagctgaaat cgatcctttt
    14101 atgcagcctg aaagagaatt gatcggtgat atctcagcca ctcttgattt attgacaggt
    14161 tcattagagc ctcaacaagt gtcagaagat gcaaaagaat atttagcatc tcttcaagca
    14221 gaattaacgg agcgggacat tgttcaatca aaaggagaag caggtatctt gcatccttta
    14281 gaagttatta acacgcttca gtcaaaagta acagatgata tgactgttac cgtagatgta
    14341 ggtagtcatt atatttggat ggcacgccac tttagaagtt atgaacctcg tcatttgtta
    14401 ttcagtaatg gtatgcaaac gcttggtgtt gcattgccat gggcgatttc tgctgcattg
    14461 gtgcgtccaa atacacaaat cgtatcagtt tccggcgatg ggggattttt attctctgcc
    14521 caggatttag aaacggcggt acgtaaaaaa ttgaatatcg ttcatttgat ttggaatgat
    14581 ggacactaca atatggtaga gttccaagaa aaaatgaaat atcagcgggc gtcaggtgta
    14641 gactttggtc cagttgattt tgtgaaatat gcagaagctt ttggcgctaa aggaatccga
    14701 gctacaagtg tagaggaatt agaaaaagct ttagaagaag gatttgcgac agaaggaccc
    14761 gtaattattg atattccgat tgattaccgt gataatgaga aattgggaga aacaatctta
    14821 ccagatcaat tctattaagg aagtgtcgac atgactgaaa aaatcttata ccagcacggg
    14881 acattaggag ctttgatggc tggcttgatg gatggaacag aaacgattgc tcatatatta
    14941 gaaaaaggaa ctctgggatt gggaacattg catgggcttg atggtgaagt catcttttta
    15001 gatggcgtag cttatcaagg aagatcagat ggctcagttg cccaattaga tggaagtgaa
    15061 cttaccccct atgcagcaat tacagatttt acgccagata ctagtttttc tgtctcaaaa
    15121 actgcagatg gagaacaatt gaaaaaagac atattagtaa gagaagccgg ggaaaaccta
    15181 tttttggcag tgaagataac tggattattc aaaaatatgc acatccgtat catgccgaag
    15241 caagaaaaac cttacagaag actagcaaaa atttcagagt ctcaaccaga attccaacaa
    15301 agcaatgtcc aaggaacatt agtcgggttc tttacgcctg aattattcca aggagttgct
    15361 gcagcgggat ttcacttgca ttttatcgat gatacacata catttggcgg acatgtaatg
    15421 gattttgaag tggctgaagg aaaagttgag attagccgca tctcgtccct tgtacagcat
    15481 tttccagttg atgatccgac ttttgttcac gaaacgattg attatgctga tttagcagca
    15541 gaaatccaac aagcagaata gaaaaagaca gcgagatgcg ttcaaggtga ttaacctgac
    15601 gtatctcgtt tttttgagga ggaaacctag cgtttacaaa aaaactgagc tataatcttc
    15661 tccatagatc aaaaaggagc ggtttttatc atgtggacag aaaaacagaa aaaagatgca
    15721 tacgaaattt tattattaca gcaacaagga ttattagaag cagaagataa ctggttagca
    15781 aatttagcaa attcatctgc attgttgaat gagactttgc ctgagactgt ctttgcagga
    15841 tattatttat tcgatggtaa tgaattgatt ttaggaccgt tccaagggcg agtttcttgc
    15901 acacgtatca agatgggaaa aggagtttgt ggagaatcag ctgaaaaaca agaaacattg
    15961 atcgttgatg atgtcaaaac ccatgcaaat tacatttcct gcgattcagc cgcacaatca
    16021 gaaatcgtag tgccaatggt aaaagaaggt aatttaatcg gtgttttaga tatcgattgc
    16081 ggagtaacga aagggtatga tgaaatcgat caagcatttc tagaaaaata tgtagatctt
    16141 ttattagcaa attttaatat aaatgctttt tcatttatta ataactaaaa tcgtctattg
    16201 aaacaaaaaa gaagagaaat caagaataaa aagagccgga aagacagtgg gcatttctgt
    16261 ttttcggttt ttttattttt ttataaaatc acaagtgtta ttgattttca taatcatatt
    16321 ttaatggtat tatcatttta aataatggaa aaacattaag gatggatgaa atatgaataa
    16381 cgaaactatc attttaggaa aaaaatatat ttgccaacct attggcttga aacaaaaagt
    16441 ggttggagaa gtaatcagta aattagaaaa ttgtgttgtg atctgcgtag acgaatatca
    16501 tgacgtcgat cgcaatgaaa tattagaaaa atgcggaaaa gtagtggcaa aatatactca
    16561 cgtttatgag ttggaaacaa cagaatatct atataactat agcaacaaat atgaacatac
    16621 tttagtttca taaagattta aataaagtgc cttcaaaagc gagaagacca agcttttgaa
    16681 ggcactttat ttagttggca gtgattgttc atgatttttg atttattcaa aaggttcgcc
    16741 tagagaatct gtctctgtaa cgaggcctgg tggagaaact cgataaaaac ctatactgcc
    16801 agaactgtcc tattttcgga tagacaaact agtagtttta aaaagatcat ccgatccaat
    16861 catttcaaaa aatgcaaaac tgatatcagg atcatttagc tcaggcttgt tatcgtaaag
    16921 catttgtaaa ggttgcattt agttaggagt aaacgcgaaa ctatcatcat tatttgctga
    16981 agaagatgaa gaagctaatt cagagtttgt ttgaaataaa ggagacgtgc tgacagtttc
    17041 tttaccctgt tttttgcaga ggtagaaact tttatatcgg aagtttctac cggagaattt
    17101 ttctcatttg tagaaattgt tgaatcgata ctattcgaaa tttgcgtatc tgaaggtatg
    17161 ttctttgatg cagaagtccc acaagcagta agtaacaata aatttgataa actgataaac
    17221 agaattcttt tcattatgta cacactcctt atagtatcgt ttagcataca cctatgctca
    17281 gtattaggca aaatcaatgc aaaactatca agtcttttat agtatctatt agtcttagta
    17341 atacatatat ggagagggtg atatcccagt tcaaaccaga tacattggtt accatctgta
    17401 ttaacgatta tgcctctaaa cgcttttttt atgaaaaaat ttataagtga aaacgtaggt
    17461 atgatattat ctagaggtaa tttttttggg tatttaaata gttgctagga ggatagctgg
    17521 gagcgtcaat aattttgtgt aaataaattg tcctcctgca aaataattag ttactcagta
    17581 aacattgaaa ctaatgtatc ggttacctgt tgaaaacctt tatggcttct gtttagaaat
    17641 ttttgattgt atgtatcaaa aatgctgact agaaagcgtt ctagtgattc ttcattttga
//
LOCUS       DAFEIE010000052        17106 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFEIE010000052
VERSION     DAFEIE010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.054"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            7..1398
                     /locus_tag="LP345_002006"
     CDS             7..1398
                     /locus_tag="LP345_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL1760780.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="LP345_002007"
     CDS             1414..2454
                     /locus_tag="LP345_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1760781.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="LP345_002008"
     CDS             2473..3558
                     /locus_tag="LP345_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBL1760782.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="LP345_002009"
     CDS             3591..4553
                     /locus_tag="LP345_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL1760783.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5979
                     /locus_tag="LP345_002010"
     CDS             4546..5979
                     /locus_tag="LP345_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBL1760784.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            5976..7046
                     /locus_tag="LP345_002011"
     CDS             5976..7046
                     /locus_tag="LP345_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760785.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7033..8454
                     /locus_tag="LP345_002012"
     CDS             7033..8454
                     /locus_tag="LP345_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBL1760786.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8467..9474
                     /locus_tag="LP345_002013"
     CDS             8467..9474
                     /locus_tag="LP345_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1760787.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9486..10490
                     /gene="neuB"
                     /locus_tag="LP345_002014"
     CDS             9486..10490
                     /gene="neuB"
                     /locus_tag="LP345_002014"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBL1760788.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10487..11635
                     /gene="neuC"
                     /locus_tag="LP345_002015"
     CDS             10487..11635
                     /gene="neuC"
                     /locus_tag="LP345_002015"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBL1760789.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11608..12285
                     /locus_tag="LP345_002016"
     CDS             11608..12285
                     /locus_tag="LP345_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL1760790.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12275..13417
                     /locus_tag="LP345_002017"
     CDS             12275..13417
                     /locus_tag="LP345_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBL1760791.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            13430..14407
                     /locus_tag="LP345_002018"
     CDS             13430..14407
                     /locus_tag="LP345_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1760792.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14407..15315
                     /locus_tag="LP345_002019"
     CDS             14407..15315
                     /locus_tag="LP345_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBL1760793.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15316..16068
                     /locus_tag="LP345_002020"
     CDS             15316..16068
                     /locus_tag="LP345_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBL1760794.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16073..17020
                     /locus_tag="LP345_002021"
     CDS             16073..17020
                     /locus_tag="LP345_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL1760795.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6163 a         2190 c         3090 g         5663 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaaacat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accatccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatat
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
     6001 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
     6061 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
     6121 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
     6181 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
     6241 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
     6301 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
     6361 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
     6421 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
     6481 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
     6541 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
     6601 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
     6661 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
     6721 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
     6781 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
     6841 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
     6901 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
     6961 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
     7021 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
     7081 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
     7141 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
     7201 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
     7261 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
     7321 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
     7381 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
     7441 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
     7501 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     7561 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     7621 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     7681 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     7741 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     7801 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     7861 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     7921 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     7981 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     8041 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     8101 aaaacatcgt ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac
     8161 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     8221 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     8281 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     8341 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     8401 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     8461 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     8521 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     8581 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     8641 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     8701 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     8761 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     8821 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     8881 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     8941 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     9001 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     9061 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     9121 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     9181 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     9241 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     9301 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     9361 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     9421 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     9481 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     9541 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     9601 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
     9661 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
     9721 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
     9781 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
     9841 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
     9901 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
     9961 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    10021 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    10081 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    10141 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    10201 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    10261 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    10321 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    10381 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    10441 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    10501 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    10561 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    10621 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    10681 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    10741 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    10801 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    10861 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    10921 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    10981 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    11041 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    11101 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    11161 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    11221 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    11281 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    11341 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    11401 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    11461 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    11521 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    11581 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    11641 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    11701 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    11761 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    11821 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    11881 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    11941 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    12001 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    12061 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    12121 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    12181 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    12241 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    12301 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    12361 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    12421 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    12481 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    12541 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    12601 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    12661 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    12721 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    12781 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    12841 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    12901 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    12961 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    13021 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    13081 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    13141 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    13201 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    13261 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    13321 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    13381 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    13441 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    13501 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    13561 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    13621 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    13681 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    13741 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    13801 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    13861 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    13921 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    13981 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    14041 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    14101 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    14161 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    14221 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    14281 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    14341 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    14401 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    14461 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    14521 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    14581 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    14641 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    14701 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    14761 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    14821 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    14881 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    14941 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    15001 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    15061 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    15121 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    15181 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    15241 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    15301 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    15361 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    15421 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    15481 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    15541 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    15601 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    15661 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    15721 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    15781 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    15841 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    15901 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    15961 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    16021 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    16081 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    16141 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    16201 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    16261 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    16321 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    16381 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    16441 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    16501 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    16561 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    16621 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    16681 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    16741 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    16801 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    16861 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    16921 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    16981 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    17041 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    17101 gataga
//
LOCUS       DAFEIE010000053        17005 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFEIE010000053
VERSION     DAFEIE010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.055"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..124)
                     /locus_tag="LP345_002022"
     CDS             complement(<1..124)
                     /locus_tag="LP345_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBL1760796.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVF"
     gene            complement(228..539)
                     /locus_tag="LP345_002023"
     CDS             complement(228..539)
                     /locus_tag="LP345_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL1760797.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(541..738)
                     /locus_tag="LP345_002024"
     CDS             complement(541..738)
                     /locus_tag="LP345_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBL1760798.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1132..2859)
                     /locus_tag="LP345_002025"
     CDS             complement(1132..2859)
                     /locus_tag="LP345_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBL1760799.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2852..4045)
                     /locus_tag="LP345_002026"
     CDS             complement(2852..4045)
                     /locus_tag="LP345_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1760800.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4232..4876)
                     /locus_tag="LP345_002027"
     CDS             complement(4232..4876)
                     /locus_tag="LP345_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1760801.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4970..5104)
                     /locus_tag="LP345_002028"
     CDS             complement(4970..5104)
                     /locus_tag="LP345_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBL1760802.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP345_002029"
     CDS             complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP345_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBL1760803.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFFMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7235..7708)
                     /locus_tag="LP345_002030"
     CDS             complement(7235..7708)
                     /locus_tag="LP345_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBL1760804.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8109..8333
                     /gene="nrdH"
                     /locus_tag="LP345_002031"
     CDS             8109..8333
                     /gene="nrdH"
                     /locus_tag="LP345_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBL1760805.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8492..10651
                     /gene="nrdE"
                     /locus_tag="LP345_002032"
     CDS             8492..10651
                     /gene="nrdE"
                     /locus_tag="LP345_002032"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBL1760806.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10701..11666
                     /gene="nrdF"
                     /locus_tag="LP345_002033"
     CDS             10701..11666
                     /gene="nrdF"
                     /locus_tag="LP345_002033"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBL1760807.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11755..12894)
                     /locus_tag="LP345_002034"
     CDS             complement(11755..12894)
                     /locus_tag="LP345_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1760808.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13203..13916)
                     /locus_tag="LP345_002035"
     CDS             complement(13203..13916)
                     /locus_tag="LP345_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBL1760809.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP345_002036"
     CDS             complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP345_002036"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBL1760810.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15105..16637
                     /locus_tag="LP345_002037"
     CDS             15105..16637
                     /locus_tag="LP345_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1760811.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16828..>17005)
                     /locus_tag="LP345_002038"
     CDS             complement(16828..>17005)
                     /locus_tag="LP345_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1760812.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3494 c         2909 g         5323 t
ORIGIN      
        1 aaaaaacaca ttccactaaa tttgatgccg gttttccttg aggttttgtt ccagcacctc
       61 ctttaatttt tttaagctct tgatctgaac attgtttagc atttagtcta tttttttctt
      121 ccattacgat tccccctaca aactataaat acttttatgt cactgattca atatacctat
      181 ttttctaatc aaaaaatttt gagacatatt taatattata agtatcatta aaattgagat
      241 ttatctccat aatctgctcg atataaacca tttattccag cagttcttcc aatttcactc
      301 aaatttctta ttaattcctc ttgatattca gtgaatctta ttttattagt ataagcagta
      361 aaatatagat aattcaccaa tctatttatt aaaggactgg gatctaattc atatttttgt
      421 ttttctaatt ttaaatatac cttttgtaaa acctcaagaa tatcagaata tttaggatct
      481 ttacttatag atatatcatt atataattca tgaacaattt gcttagcatt ttttttcatt
      541 ttagcacttc cctggaattg ctccacctaa aaaaccacct atagacattc ctgcaataca
      601 agtagttgcc ttggcccaat cgaccgtaca tttattttta gtgcaataca ctccatttcc
      661 ataatatttt ccactatgag tggtaccccc atagataagt tgtgtctctt taatagacaa
      721 aatttttaaa tgtttcataa tctaatcacc cctaaattaa tgtttttaga ctattattct
      781 aacattcatt aaatttcaaa aaacaattcc ttcttgaaac gtagcaaaat aattcctgaa
      841 taagaattta atcactttta agtatataaa ctatgtatat tctttaatat tttttgagaa
      901 tgcacttcgt acataataaa ctttaatcac attagtcttt catacctacg atcgatctct
      961 ttgactcgca cccataaatt cataatagtt tgtcggcgtc tttgaacgtt tcgaagatga
     1021 gctacgcatt ctcttttttt atagacaaaa aagatagaga cgaacatgga gcttccaaat
     1081 ttggatattt gatccaattt tggaagctcc atttatttcg tgtctgtctt tttatttttt
     1141 ccagctttcg actaattctt ggttctcttt gatccagtct tttgctgctt gctgtggatc
     1201 ttttccattg ttgatttcca acataacttt ttccatatct ttttctgacc aatggaaatt
     1261 gtctaatact ttgtaagctt ctggctggtc ttctttcaat ccttttcgaa ccatcgtatg
     1321 gatctgctct tcgcttccca ttccgttttc aggatcttct aagtatttca gatcatattt
     1381 ggcaaacatc caatgaggtg tccatcctgt aactacaatt ggttcgtgtt ttttgatcgc
     1441 ttgacctagt gcaacggtca ttgctcctga agaagatgtc tctactttcc agtctttcaa
     1501 gttgtcatat ttttggatcg tgttttcagc agccgtaact acaccagctc ctggctcgat
     1561 tcctatgatt ttcttacctg cctgatcggt taactcatcg atcgaattta catccatgta
     1621 ggctggcact gctaaaccaa cttttgctcc tgtcaaattg gcacctaggt cttcgacttg
     1681 atctttatat tgtgcatatt gtgaaccatg agttttaggt agccaagctg aaaccatggc
     1741 atctgactcg ccatttgaaa cagatttcca catgattgaa ttatctaatg gcgtcatcgt
     1801 tacatcatag cccatttgtt tcaatacttc accgactaca tttgttgaag caacttctgt
     1861 atcccattca acataagata agttgatacg ttttgtttct ttggcagatg aaaaactccc
     1921 tataccaatc gcacctaaga tcactactac tacagcacca atgatcagtc cttgacgttt
     1981 tttacttttc tgtgttgttg ctcctgcagc ttttttattg tttggctggt tcaaatgctg
     2041 tgtaaaacgg tcaatgatga ttgctaagat aactaatgca accccgttga caaatccatt
     2101 cccgacttgt gctctttgca atgctgataa tacgccgcgt cctaagccgg gtgcaccgat
     2161 catagaggca ataacgacca ttgaaagtga cagcattgtt gtttgattga tccctgccat
     2221 gatcgtactt ttagctaaag gcaattctag tttgaatagt ttttgacgac ttgtgctccc
     2281 gaatgaatca gaagcttcta ctaattcttt aggaacttgt cgaatcccta aattcgtaaa
     2341 acgaacggtt ggtggcagag caaagatgac tgaggcaaat acccctggaa ccatcccgat
     2401 accgaaaaat gcaactgctg gaatcaaata aacgaatcct ggcattgtct gcataaagtc
     2461 aaggatcggt ttgataatac tttgggcttt actgcttttt gccatcaaga tccctaatgg
     2521 taccccaatg atgatcgaga tcacactaga taaaagaaca agtgtgacag tattcatcaa
     2581 atcattccat agaccttggt tataaataaa ccatagaccg attaatgtga acaacgtaag
     2641 tcctggacgt ttcttagaaa taaagaaagc tgctaccgtc aataacaaga taaacaaagg
     2701 agctggaatc actaacagta aatttgtaat ccccgacatc actgcctgtc caatcgtttg
     2761 taaaaatgaa aataggccag aaaaagttgt cgtaaaccat tctgtgatat tttctaccca
     2821 gtttgccact ggtaattgat agttcaatag attattcatg ttcactcacc tcgcttgttt
     2881 ctgctaatgc ttcaatcaca ctacctcgga tgacgacacc ttttaatttt ccatcctcta
     2941 caactgcaag tggagtcggt gagtcataaa taatattgaa aatatcactt accaccatgt
     3001 ctttcccaat caccgtcaca ttttcatcta ggaagtcgat caatggacgt ttttgcttcc
     3061 tagcttctaa cgcttgatct gcagtgatga tccctttcag gtgtctcttt ctgtcaacag
     3121 ccatcagcat gctgacttct tcattacgca tccttgtcaa tgcaacgttt ggtccatcag
     3181 attcgatatt cgtcgtcaat gcaggtacca tgatgttttg agccgtaagc actttggaac
     3241 gatcgacttc ttccacaaat tcacgtacat aatcatttgc tggattggtc aatatttctt
     3301 cacctgttcc gatctgcatg atttcgccgt ctttcatcaa ggcgattctg tccccaatcc
     3361 gtaaagcttc attcaaatca tgggtaatga aaataatcgt tttttgaaca ttggcttgca
     3421 ggtccagtaa ttcgtcttgc atttctcgcc ggatcagcgg atcaagagcc gagaacgctt
     3481 cgtccatcag caagatctca ggatcatttg ctaaagctct ggctaggcca acccgttgtt
     3541 gcatcccacc agataactga ctaggatatt ggtctttaaa tgaaagcaaa ctagaatttt
     3601 ctaatgcttt ttctgctttt tcttgtcgtt cttctttagg tacaccacgg acttctaacc
     3661 cgtattctgt attttccaag atcgttcgat gtggaaacag accgaagttt tggaaaacca
     3721 tattgatttt atgacgacgg acttctcgca attcttcttt gcttaacttc gatacatctt
     3781 ctccatcaat atagatactg cccgaagttg gctcaatcag acgattcaat agacggatca
     3841 atgtggattt cccactcccg gaaagcccca tgatcacgaa gatttctcct tcttttacgt
     3901 caaaattcac gtcatacaca ccaaccgttg caccggtttt ctttaaaatc tccgttttcg
     3961 gctggtgatc attcatcata tctaaagcgg cttgtgtctt tttaccaaat atctttgtta
     4021 aatgttttac ttctactttt accaaacaaa ttctcctttt ttatgtaaat tcatttttct
     4081 ttctgaaaaa agtgaccaca ctatgttaac atcatgtagt cactttgtca aaaatgaaag
     4141 aaatttgctt gtccaaactg aaaaaaactt ggctaaatct ttgtaaataa aaggtttagc
     4201 caagttaata tttttttaat atttcacaca atcattctgc aagctgatgc tccgggtaaa
     4261 aaaagtttgt catacgctgt agtgtatatt catttccaat aaaatgaacg atgtcccctg
     4321 ccgtaaattt agcatagggg ccaggtgaaa caagcagttc ttcattatga gaaattgcga
     4381 taactgtggc gccagtcgcc tgccagatat tcaactcgct aattgaacgg tccagatgca
     4441 ttgctttttc tgataaagat aattcaaacg gaagtaaagg attcatctta tgtattcgct
     4501 tcgtttgatt gaccagctga tccaataatt gagaaaaatg attcagctca tcttgttgct
     4561 tctccacact tgccatgatt tctgcttttg tatcttggat ggattgtaca tcttgatatt
     4621 gcaataggaa atcttttgct ttttccttcg aagcaacaaa tgccccactt ccatgccgta
     4681 cttccatgat tccaagatct accagcacat tgatagcctt gcgggtagtc tcaggagaag
     4741 cattgtacgt actggcaagt gttgagcggg catggatctt ctcacccact ttatatcggt
     4801 tttcaacgat acgttcggct aaatcaacag caatctgctg gtagcgcggg cggacgattt
     4861 ttttctttcc agacattttc tttcctcttt ctttttttac tttccctcat cttactatgc
     4921 tctagcaaaa taagcaaaaa aggggagaat agcctcttgc aacgactgat catcgcttga
     4981 tctgttcctt ttttactggg caagctgttt gacagtcatc acaattctta ccggatttta
     5041 aacgagtata gacaattgcg cctgcacttc caaagattaa cacacttaat aagaatgtcg
     5101 ccatcctatt cctctccttc taatgacaat atagtataaa actggttctt ggattttggc
     5161 tgacggaaca aaacataaac gagtcctatc atcagtaaaa tagcaagata cgtccctaac
     5221 gctacctgtc caccctccaa taagtgtccc aactgataaa tcacaaaact aactaaataa
     5281 gctaaaccgc attgatagcc tatggcgatc caagtccatt tcttggcatt catttcccga
     5341 tggatagccc caattgccgc aaaacaaggc gcacaaagta aattgaaggc taacaatgaa
     5401 taagctgctg cgggagtata tgtgtgttgt agcacttgcc agatttctct gccattttcg
     5461 gatacttccg catgaccaaa caaaatacca aatgtgccaa taatattttc tttagcgacc
     5521 aatcctgtaa tcgctgcgac tgttccttgc cagtttcccc aaccaagcgg ctgaaaaaca
     5581 actgccagga ttcgcccgaa aaaggctaag atactttggt cttcagaaac aggttgagca
     5641 taaaaattat aagaagagct gaaccagatc acgatactag aaacaaagat aatcgttcct
     5701 gcttttttaa caaaagactt gctgcggtca taggtttgtc ttaggaccgc tgaccattga
     5761 ggaaaatgat atgcgggcaa ttccatgata aaaggagctg tatctccagc aaacaaacgt
     5821 gtttttttca agctgattcc agagaaaata attgcagtca taccaagaaa ataggcagaa
     5881 ggagctaccc aagattgatg aggaaaaaag gcccctgcta ctaaggcaat aatcggcaac
     5941 tttgcagaac aaggcatgaa ggttgtgacc atgatcgtca aacgacgatc ttgctcgttt
     6001 tcaatcgtgc gactggccat gacgcctggc actccacatc ctgtagcaat cagcatagga
     6061 atgaaggatt ttcctgaaag accgaatttc ctgaaaagtc gatccatgaa aaaagcgatc
     6121 ctcgccatat atccgcagtc ttccagaaag ctcaagcata aaaacaatat aatcaattgc
     6181 ggtagaaatc ctaacactgc tcccacgcct gcgatgatgc cgttcaagat cagctcctgc
     6241 atccatcccg ctacttgcca ttcagctaac aatctgccaa catgttctgg taaccatgta
     6301 ccaaacaatg tgtcattgat ccaatctgtc cccattgttc ctactgtttg aatagccaga
     6361 taatagatca gccacatcac aaatgcgaag atcggcaagg ctaaccaacg attcgttgca
     6421 atctgatcga ttttgtcact catcgataat tggaaagaat catttgacac aacacagagt
     6481 gtacatagtt gggtaataaa ttcataacgt tcattgacca gaatcgtctc actatcgtcg
     6541 tccaatagtt tctctgttaa ctggatcagt tgctcgatct ctttttgctg agaaactgct
     6601 atctcgtaat cctctcttac cttctgatct cgttcaaaat atttcattgc ataccagcgt
     6661 ttcttgccgc tttgttctcc tagtacatct tcaatttcat gtaaagctgc ttctaaacgt
     6721 ggatcatatg tacagggaac aggaatagaa ggccgctttt ttgcagactc ctgaatcttt
     6781 tcgattagtt tttcgattcc ttgctttttc aatacgctga ttggtaaaac tggtacacca
     6841 agaccatagg aaagcttttc tagattgatt ttttttcctt cttttttgat gacatccatc
     6901 atattcagac caatgatcat aggaatgtct aaatccaata actgcgtagt taaataaaga
     6961 tttcgttcta aattggtagc atcaataatg ttgatgatca gttcaggctg ttcctgaacc
     7021 aaataatctc ttgcaatcac ttcttctggt gtataaggag acaaagaata gatgccgggt
     7081 aggtcctgaa tatgaatgtt cggatttttt ttcaacgatc cttctttttt ttctactgtt
     7141 acgcccggcc aattccctac atattgattc gaaccagtca agagattgaa caagctagtt
     7201 ttcccgctgt ttggatttcc gactaacgcg atattcattc tttttcctcc ctttgtatca
     7261 agattagttc ggcctctgac tttcgtaacg tcagttcata ccctcgcact gtcagttcga
     7321 ttggatctcc cagaggggct agttttcgga taactatttt tacatttcgc gtcaatccca
     7381 tatccattaa ccgtcgcttc actgcgcctt gtccgtggat tgctacgacg atcccagtct
     7441 ctcctgcttt taattgatca agagaagtcc agctttcaga ggaagcagtc tttttattga
     7501 caaagatttg acctagtatt tcccgactta ctgccactcg atgacttttt accagtaaaa
     7561 tggcattgtt gcctgataaa ttgacgacga cgattttact tccggcaacg atcccgatat
     7621 tttgcaaatg gcgttttgtt ttttcttctg tttcgattcg ttcgacttga taaacgaaat
     7681 tctgctttgc ctgcgctaag gtctgcatat tgattcctct cttgtgaaat aaatcatgta
     7741 ttaaaatcat tcattatatg ttctaatttt cttacgtgtt acgcaaataa atgagaatca
     7801 ttctcacata gaatactctc ggtaattgag aatgtcaatt atacttgtga tattatgagc
     7861 gaatctttag tattgataga taaaaatgag aaaaaaatat ttcttcatag ttttccacaa
     7921 ttttttctct attaaatttg ctattttccc acacgatact tgttttcagc tcttttttca
     7981 aaaacacaaa acttagtatt ccacagtttc cacaacacaa tatgtagtgt ttgttgtttg
     8041 acttttttac taagagtttt atactatcta ttatagataa taagaatgtg ttagaggagg
     8101 cactcaccat gaacgtaaaa atcttttcta aaaataattg tatgcaatgt aagatggtca
     8161 aacggttttt aacagaaaat caaattgctt ttgaagaagt caatatcgat gaacagcctg
     8221 aagcagtaga ctggttgaaa gcacaaggat tccaaagtgt tcctgtcatt acttctgatg
     8281 cagaaacagt tatcggattc cgtcctgatc agttgcgtaa acttgccagc taacatgact
     8341 aaaagaatca aaacgtgata catggatttg aagggcttga gacagcacca gtttttgtcg
     8401 caaacttcca aatccttttt taaagcttaa aaacaatgca atgatttgca atcaagcatc
     8461 atcaaatacg aaatgaaggt tgggcgtacg tatgagtctt aaaaatttac aagatgtcag
     8521 ttatttcaag ctgaataatg aaatcaatcg gccagtcaat ggtcaaatcc ctttgaataa
     8581 ggataaagaa gctttagttg ccttttttga ggaaaatgtc aaaccaaata cgatgacttt
     8641 tccatctatt atggaaaaaa tcaattactt gatcgatcaa gaatatatag aagcagaatt
     8701 cattcaattg tattcaccat catttattga aaagctatat caatttttgg acgagcaaca
     8761 tttttctttc aaatctttta tggctgctta caaattttat tctcaatatg cgttgaaaac
     8821 caacgacggt tccgcttatc tggaaactta tgaagatcga gtagccttca atgcgcttta
     8881 ctttgcgaac ggggatgaag aattagcact tgctcttgca gacgaaatga tccatcaacg
     8941 atatcagcca gctacacctt ctttcttgaa tgctggacgt aaacgtcggg gcgaattggt
     9001 gtcttgtttc ttgactcaag tcactgacga tatgaactct atcgggcgct caatcaactc
     9061 tgctttgcaa ttgtcccgta ttggtggcgg cgtagggatt actttatcaa atcttcgtga
     9121 agccggcgct cctatcaaag gatatgaggg tgctgcaagt ggtgtcgttc cagtcatgaa
     9181 attattcgaa gatagtttca gctattctaa tcaattaggt cagcgtcaag gagctggcgt
     9241 ggtttatttg aacgttttcc atccagacat tattgctttc ctttcagcaa aaaaagaaaa
     9301 tgcagatgaa aagattcgcg taaaaactct ttctcttggc gtgatcgtac ctgataaatt
     9361 ttatgaattg acacgtaaaa acgaagatat gtatttattt agtccatata gtgtcgaaaa
     9421 agaatatggt gtcccattct cttatgtaaa tattacagct gagtatgatc atctagttgc
     9481 aaatccaaac attcgcaaac aaaaaatcaa agcgcgtgat cttgaaaatg aaatctcaaa
     9541 attacaacaa gaatctggct atccttacgt aatcaatatt gatacagcga accgcgagaa
     9601 tccaatcgat ggcaagatca tcatgagtaa tttatgttca gagattttac aagttcaaac
     9661 gccttctgtg attaacggca aacaggaata tgaagtatta ggaacagata tctcatgtaa
     9721 cttaggctcg acaaatatcg tgaatttgat gcaaagccct aactttggtc aatctgtgcg
     9781 tacgatgact cgtgcattga catttattac agatgcatct gatatcgatg tcgtaccacc
     9841 gatccaaaac ggaaataagc tgaatcatac gattggatta ggtgccatgg gcttacacac
     9901 ttatcttgca aaagaacaaa tggaatatgg ctcagaggat tcattagact ttacaaatat
     9961 ttacttcatg ctgttgaatt attggacact tgttgaaagc aacaatatcg ctcgtgaaag
    10021 aaaacaagtt ttccataatt ttgaaaaatc agcttatgct gacggcactt atttcgaaaa
    10081 atacgtaact ggagaattcc agccaaaatc agaaaaagtc aaagcattgt ttgaaggcat
    10141 ttttatccca actgctgaag attggaatgc tttgaaacaa gcagtaatga aagatggact
    10201 gtatcatcaa aatcgcttgg cagtagcacc aaatggctca atttcatata tcaacgatac
    10261 gagtgcaagt attcatccta tcactcgcat gatcgaagaa cgccaagaga agaaaatcgg
    10321 taaaatttat tacccagcgc cttatctatc caatgagacg attccgtatt acacttctgc
    10381 ttatgatatg gacatgcgta aagtaatcga tgtttatgca acggcacaac aacacgtcga
    10441 tcaaggcatg agtttgactt tattcatgcg ttctgaaatc ccagaaggca tttatgaatg
    10501 gaagacaaca acgaagcaaa cgacacgtga tttgaatatt ttaagacatt acgctttcca
    10561 caaaggaatc aaatccattt attacgtacg tacctttact gatgatgcag aagaaatcgg
    10621 aagcaatcaa tgtgaaagct gcgtgatcta atatcataga tagattcgct tattcatatt
    10681 ttaattaaag gagcattctc atgtcagaaa catattatga agcaataaac tggaatgaaa
    10741 ttgaagatat cattgataaa tccacttggg agaagctgac agagcaattt tggctagata
    10801 cacgtatccc actttcaaat gacctagatg attggcgtac attgtctcaa ttggaaaaag
    10861 atacagtagg acatgtattt ggcggtttga cactgctaga tactgtccaa tctgaaagtg
    10921 gcatggatca gttgcgtaaa gatgtccgca ctccccatga agaagccgtt ttgaacaata
    10981 ttcaattcat ggaatccgtt catgccaaaa gttattcttc tatttttagt acactgaata
    11041 cgaaaaaaga aatcgaagaa atttttgact ggacaaatac gaatccttat ctgcaaaaaa
    11101 aagctgagcg tatcaatgaa atctacaaac acggtacacc gctagaaaag aaaattgcca
    11161 gcgtcttttt agaaacattc ttgttctatt caggttttta tactcctctt tattatttag
    11221 gaaacaacaa attggctaac gtagcagaga tcatcaaact aatcatccga gatgaatctg
    11281 tacatggaac ctacatcggt tacaaattcc aattaggatt caacgagtta cctgaagcag
    11341 aacaagaaac gttaaaagac tggatgtaca atcttcttta tgagctttac gaaaacgaag
    11401 aacgttatac agaagaatta tacgatccaa tcggctggac agaagaagtc aagacattcc
    11461 tacgctataa tgccaacaaa gcattgatga acctagggat ggatccactc tttccagata
    11521 ctgccaatga tgtcaaccca atcgtaatga acgggatttc aacaggcaca agcaaccatg
    11581 acttcttctc acaagtcgga aacggctatt tgttaggtca tgtagaagcg atgaaagacg
    11641 acgattattt gattggattg gaataaggat ttattttaat tcaaaaattt ttcgaaaaat
    11701 aaaaagagtt tagcgtacag atattttaaa tgtacactga actctttttt atgcttattc
    11761 acttgtttct tccagcactt ttggactgtc taacttttcc gaaacatgtt ccattcttct
    11821 caataaatag attttccgga tatttaatat tatcgtctta atcactgcat agacaggtat
    11881 gcaaatcagc atgcctaata ttcctgcgac acttcctgct ccaatcaata ccaagatgat
    11941 cgtcaaagga tggatattca ttgatttccc aaataacaac ggcttgatca aatttccatc
    12001 taattgttgg atcactaaaa tcgacaacgc catatacaaa gcttgaaatg gagagataaa
    12061 caaaccgaca atgattgctg gtaccgctcc aataaaaggg ccgacatacg ggataatatt
    12121 cgtgattccg caaatgaccg caagcaacaa gctataaggc tgatcgaata ttctcattgc
    12181 caaaaagctc attacaccaa taatcaaagc atctaagatc gtactgctga tataggcaga
    12241 taatgtttcg tttaattctt ttaccgtttg gcgtaactct ttacgaatcg ctttcggaaa
    12301 gaagtgagac aacgcatcaa taaatttgtg cccatccttg aacataaata gcaaaataaa
    12361 tggaacggta aataacaaaa taaaaaattg catcataaat gaaatgattt ttgagacact
    12421 tgcagataaa ctgactaata tgatattgaa caaattacta agagataaat ttgctgatgc
    12481 taattgttct tccaaattga aatttttaaa ctcttcccgc tgcgccaatt catttaacca
    12541 tttgcttgtt tcatctgcat acattggcaa gctctgggtc aattgaattg tctgttccat
    12601 taactgaggc actacattca tgacagttaa aacaactaaa atgattacga ccaaaaacgt
    12661 caataaaaaa ccgaacactc tcgggatccg atgcttttcg agaaaaacaa cgattggatc
    12721 gaacatataa tagataaaac cagcaacaag caatggtaaa aaaattgccg aaagcatttt
    12781 caatattgga ctaaaaatat tcggcatttg taaaataaag tacacgccga tgatcgtgag
    12841 tactagctcc actgtccaga aaaataattt tgattgttta aaacgtgatt gcatacatct
    12901 cctccaaggt cctttgatac ttctattcta tcatttaaca aagagttacg cgctgagatt
    12961 ttcatttgct taaaaaaaac aaaaaaaata aacatatttt aatgagtaga cgagtactta
    13021 aacaaaaaca cggtttggag tagtgacaaa aattatactg cagtcccttt ttccaaataa
    13081 acggtgttca aaagcttgca tcttcgtaat aagcccagcc aaacgaaaaa tataaggaac
    13141 tatttttatt tggctgggct tattacttga tgtaggacat ctattttaca acctcagatc
    13201 atttattgcg caatactgac taaatgcaac tttgtgatat ttttgtgtac ggacaactcc
    13261 tcgatcacat cggcataagt gagccctttt ggaagatcaa tcgtatagat atttttgtac
    13321 actcggtagt catcaacgaa ttttacgtca aaattcacat cttcgattac gatatttttc
    13381 tcttcaaaat aatcggtaag aaaatctttg gtttcttttc tatggataaa ttggatttct
    13441 aactttttag tcgtaggtac atggatcacg cgtttcacta ctgtgagtgc aatagcaatc
    13501 ccgataaaac tgatgatcgc aatggaatag taacccatgc cgatggcgat ccctaatcca
    13561 gcaattgccc ataaagaagc ggcagtcgta agtcccgtca ccgattgttt cgtgacgatg
    13621 atcgttcccg cgcctaagaa accgacacca ctcaccactt gagcaatcag ccttgcttca
    13681 tctgaacgaa tcgttccagc aagctgtgga tactctaaag catctcttaa tgcaccacta
    13741 gcgatctcaa cttggatcaa tgcaatgata catgctccca tacaaactaa aatatgcgta
    13801 cgcatacctg ctggacgatt tttatattgt cgttcaaaac cgattgctcc gccaaatagc
    13861 atagcgatcc ctaaacgtaa aataatctct ggaattgtca ataccatatc attcatctaa
    13921 acaccctcca gtccaatata tcatgtctga aaggagcaga caaaaaaagt gcaattttta
    13981 cctcttacga aaaaaggact gtgacaaaat ttttgtcata gtccttttta tgaataaacg
    14041 gtgttcaatc agctgaccct cggtattact caacaaacgg caaaatatgg ggagctattt
    14101 ttcctttgtc ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttagcctac
    14161 tattgaaaat tacaacttac ttgctgcttc ttcatcgatg atcacaacaa cattgtcgtg
    14221 attttgcaat acacttgctg gcaaatgatt cgttacaggt ccttcaatca tccctttgat
    14281 tgcatcagct ttgctttcgc caaatgccat caagacgatt tctttacttt tcataattga
    14341 accgattccc attgaaacag cttttgttgg tacatcttct gctttatcga agaatcgttt
    14401 gtttgcattg attgttgatt ctgttaagtc aactactgaa gtcgttccgt caaatgaagc
    14461 accaggttca ttgaaaccga tatgtccatt ttgcccgatt cctaagattt ggatatcgat
    14521 tggatgtgca tcgatgattt gatcatactt tttgcatgct gcttccagat cttctgcttt
    14581 tccatctggt acaaacgttt ctttgaatgg ttttttatca aataattgga catccatgaa
    14641 atgacggtag ctttgttcat ctgaaccgcc tagtccaacg tactcatcta agtttacaga
    14701 agtcatttca ctgaaatcca aatcgcttga agtcatttct ttatataaag taactggtgt
    14761 gcttcctgtt gccaatccta atacttttgc acctttgttc ataccttctt tgatgatttc
    14821 aaatgctttt tttccgcctt cttcagcgtt ttttacacga atgatttcca tagtgattgc
    14881 tcctttatat tttggtatag cccaattata gcattctttt tttcttttta caataattag
    14941 tatagaccaa attgcatttt tttcattttc ttgacaataa ataggaatcc gtgttaggtt
    15001 tcataagatg gttcaatcaa acaatccatg ttgcatgaaa accaagcaag tgattcactg
    15061 tggacgcttt atgtctgcag tttttttatg aaaaaggagt tattatgagt atactgacat
    15121 taaacaacat tacccagcaa tttggcgaca aaatcctcta tgaaggtgtc gatctgcaat
    15181 taaatgctgg cgaacatctt gggctgattg gacaaaacgg agccggtaaa agtacattga
    15241 ttaaaatcat cactggtgag atcttaccag atgacggaca gatccattgg caaaaaaata
    15301 ttcacaaagg ttacctcgat caatatgtgg aagtcgatga aacattaaca atcgaagaat
    15361 ttctaaaaac tgcgtacgca aaagaatacg aaaaggaaga aaaaattgct tttctttacc
    15421 aaacatatag cgagaccttc gatgattcct tgctggaaaa agctgggaaa ctccaaacgg
    15481 aattagacca aggagtgttt tatcaaatcg acaccttagt tgctgagatg agcagcgggt
    15541 tggggatcga tgtcttaggt ttagattcac tgttgaaaaa tctaagtggt ggacaacgtt
    15601 caaaggtgat tttagcaaaa ctacttttag aaaacccaga tgttctgatc ttagatgaac
    15661 caaccaatca cttagatgat cagcatatcc aatggctgac gcagtttctt caggattttg
    15721 acggtgcgta tatcgtgatt tcccatgacc aagaatttct tgatcagatc accacccata
    15781 tcgcagacat cgagtttgga aagattacta agtatactgg ccatctaaaa caagcattga
    15841 aacaaaagga acaaaatcgc gaaagctatt tgcgccaata tcatgctcaa caaaaacaaa
    15901 tcgaaaagac cgaagcttat attcgaaaat acaaagccgg ttcccgatca acgatggcaa
    15961 aaagccgaca aaaacaatta gataaaatcg aacggctgac gcctccagct tcagcaagta
    16021 aagctgtctt tgattttcca ttctcgccta ttgtcacgac attagcagtg gaaacaactg
    16081 atttagtcat cggatatgat cgaccgctac ttgcacccat caatttgacc atccgctttg
    16141 gtgaaaatat tgccattcga ggcttcaacg ggattggaaa atctacttta ttaaaaacac
    16201 tgatcggtga gattgaaaaa ataagtggcg atttccactt cccagataac acaaaaatca
    16261 attacttttc acaagatctg tactgggaaa atccattaga aacaccacta caatatttaa
    16321 gcagtcaatt tccaaaagcg actatcaaag aattacgtcg ccaactagct aaagcagggt
    16381 tagttaatca attagcaagt gaacctctca ctacattaag tggtggggaa caaactaagg
    16441 tgaaacttgc acagttgaca atgaaccaag gtaatttact gattctcgat gaaccgacga
    16501 accatatcga tcaagaaacg aaagaaagct tacaagacgg gatacagaaa tttccaggaa
    16561 cagtaatcat cgtctctcat gaacaagaat tttatcaaga tcttgtgcaa cgagtcattg
    16621 agattgaacc aaaataaacg tttgattgaa tagttgaaaa aaaggagctg tgacaaaagt
    16681 tttgtcacaa ctccttcttc tgaataaatg gtggccaatt agctgacctt cggtattagc
    16741 tcaaaaaacg gcaaaatatg aggagctatt tttatttggc tattcttatt acttgatgca
    16801 gaacagcttt tcacaacctc ttttcgtcta ttttttattt tcgagatttc tctttccttt
    16861 aaaaacaact gtttgaaaga agaacgcaca tccttgaaaa acaagcccgc taaccgttac
    16921 acctaaccag ccatactgct gccacattgt cgtccctagc aatgaaccag ccgcacctcc
    16981 aataaagtac ataaacataa ataca
//
LOCUS       DAFEIE010000054        16843 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFEIE010000054
VERSION     DAFEIE010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16843
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.056"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            163..1104
                     /locus_tag="LP345_002039"
     CDS             163..1104
                     /locus_tag="LP345_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBL1760813.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1173..1904
                     /locus_tag="LP345_002040"
     CDS             1173..1904
                     /locus_tag="LP345_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBL1760814.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2048..4228
                     /locus_tag="LP345_002041"
     CDS             2048..4228
                     /locus_tag="LP345_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBL1760815.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4248..4730
                     /locus_tag="LP345_002042"
     CDS             4248..4730
                     /locus_tag="LP345_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBL1760816.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            4746..5507
                     /locus_tag="LP345_002043"
     CDS             4746..5507
                     /locus_tag="LP345_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL1760817.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            5638..6972
                     /locus_tag="LP345_002044"
     CDS             5638..6972
                     /locus_tag="LP345_002044"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBL1760818.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7279..7764
                     /locus_tag="LP345_002045"
     CDS             7279..7764
                     /locus_tag="LP345_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBL1760819.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            7757..8440
                     /locus_tag="LP345_002046"
     CDS             7757..8440
                     /locus_tag="LP345_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBL1760820.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8566..11211
                     /gene="polA"
                     /locus_tag="LP345_002047"
     CDS             8566..11211
                     /gene="polA"
                     /locus_tag="LP345_002047"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBL1760821.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11256..12092
                     /gene="mutM"
                     /locus_tag="LP345_002048"
     CDS             11256..12092
                     /gene="mutM"
                     /locus_tag="LP345_002048"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBL1760822.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12056..12685
                     /locus_tag="LP345_002049"
     CDS             12056..12685
                     /locus_tag="LP345_002049"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBL1760823.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            12737..13069
                     /locus_tag="LP345_002050"
     CDS             12737..13069
                     /locus_tag="LP345_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL1760824.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13381..13872
                     /gene="nrdR"
                     /locus_tag="LP345_002051"
     CDS             13381..13872
                     /gene="nrdR"
                     /locus_tag="LP345_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBL1760825.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            13895..15268
                     /locus_tag="LP345_002052"
     CDS             13895..15268
                     /locus_tag="LP345_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL1760826.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15268..16194
                     /gene="dnaI"
                     /locus_tag="LP345_002053"
     CDS             15268..16194
                     /gene="dnaI"
                     /locus_tag="LP345_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBL1760827.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16323..16763
                     /locus_tag="LP345_002054"
     CDS             16323..16763
                     /locus_tag="LP345_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL1760828.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         5749 a         2949 c         3709 g         4436 t
ORIGIN      
        1 tttttctgtg cgaaacagga aagcgaagtc tttttaattc aaataataat attatgtaaa
       61 caaaaaactt tccatgcgta attatacaca agcaaataaa tcgtcaaatg cgaacgcctt
      121 ctttatactg tttaggaacg aaaagaagga aggaagaaat acatggatta tcaagtactg
      181 ctttattaca attatacaaa aatcgaagaa ccagaggaat ttgccaaaaa tcatttagcc
      241 ttttgcaaat ctttggatct taaaggtcgt attctagtag ctgaagaagg aataaatggt
      301 actgtgtctg gaaccgttga aaacacgact gcctatatga aagcaatgaa agctgatcct
      361 cgatttgctg atacgatgtt caagatcgat ccaagcgaag gacatgcctt taagaagatg
      421 tttgtaagat accgtccaga gcttgtaagt ttaaagctag aagaggacat tgatccaaac
      481 caagtgacag gtgcctatct ttcaccgcaa gaatttaaag aagctatttt agatgaacag
      541 acagtggtga ttgatgcacg gaatgattat gaatatgact tgggacattt tcgaggggct
      601 gtacgcccag atatacgcag ttttcgagag cttccagact ggatccgcga gcacaaagaa
      661 gaatttatgg aaaaacgggt agtgacctac tgtactggtg gcattcgttg cgagaagttt
      721 tctggttggc ttgtccgtga aggattcaaa gatgtcggac agctgcatgg cggtattgct
      781 acttatggta aggatcctga agtccaagga gaattatggg acggcaagat gtatgtgttt
      841 gatgaacgga tcgctgtcga tatcaaccaa gtagataaac aaatcgtcgg tcgcgactgg
      901 tttgacggaa caccatgtga acgatatatc aattgtagca atcctgagtg caatcgtcag
      961 attcttgctt ccattgaaaa tgaagaaaaa catttaggag catgtagcat agagtgtgcg
     1021 aaacatccgc gcaatcgcta tgttcaagac catggaatct ctccagaaga agcagaactg
     1081 cggtttacag ctttaattaa atagaaaaca atagttttga ttgtcgacca tttccaatat
     1141 gcgctatact agcgttgagg atggtgatcc acatgaaatc attgatttat gctattgggg
     1201 atgtccatgg caaacatgag ctttttgaaa aacttattca ctattatgat ccaaagatcc
     1261 atcagcttgt tttattaggg gatctcaatg atcgaggtcc tcgtacaaaa gaatgttttt
     1321 tattaggaaa gcaattagtc gaagaaacag gagccattta cctccgggga aaccatgaag
     1381 aatatttttt gcaatttctg caatcaccgg aggactggta tgcgccttat atgagaaatg
     1441 gtggaaaaga aacgtttgaa agcctgattc acccaggggc atcggaggaa tactccccaa
     1501 ctgaaatctc gatgatgatc caatcgagat attcagaact gattaaattt ttagtccagc
     1561 gccccttgta ttatgaatgg gaaaattatc tttttgtcca tgccggtgtg gatttgacaa
     1621 agaaagactg gcgtaagaca agtctaagag actttatttg gataagggaa ccatttcatg
     1681 aagggaaaaa caatacaggt aagacaattg tatttggaca tacgattaca ccaatgctcc
     1741 atggagatat gcagacaaca gacctctgga ttcaggatca taaaatcgga atggacggtg
     1801 gggctgtatt cggagggtca ttgcatgggg ttgtttttga caaggaaggt attcttcaag
     1861 atattgaata tcagaacaac gaaggacctt ggcatggaat ctgactaatg gaaagaatga
     1921 aggagctgtg actttgttgc ggctcttttt atttttatag agaatattgt ttctttcagt
     1981 agtttaaccc aggataaaaa gtatgataga ataaagaagc aatttttagc agaaaagagg
     2041 cattttaatg acggaaaatt tgaaccagac gatcattcag cttgtacaaa aagaactttc
     2101 agactatcgt cctaagcagt tgactactgt acttaatttg ttaaatgaag gaaacactgt
     2161 tccttttatc gcgcgttacc gaaaagaaat gactggaagt cttgatgaag tccagattcg
     2221 tgaaatcgaa gagcggtatg cctatcttga aaacttagaa aaacgtaaaa ctgaagtgat
     2281 tcggctaatc gatgaacaag ggaaactgac tcccgagtta gaagcagaaa tcacccaagc
     2341 cgtgaaaatg caacaagtgg aagatttgta tcgtccatac aaacaaaaac gacggacaaa
     2401 agcaacgatt gctaaagaaa aaggacttga accactcgcg aagtggctga tgcagcttac
     2461 agatggagag gtgcaatctg aagcagaaaa atatattgac aaagaaaaag aagtctcttc
     2521 tgccgaagaa gcgttgcacg gtgctcatga gattattgct gaacaagtca gcgataatgc
     2581 aaaatttcgg acttggattc ggtcttatac gtataacaaa ggtatgtatg tcagcaatgt
     2641 caaggatgag caagcagatg aaaaaggcgt atatgaaatg tattatgact ttgcagaacc
     2701 cgtccataaa atggtttctc atcgaatatt agctactaat cgtggagaaa aagaagatat
     2761 tctgaaagta ttctttcaag tagatgaagc agcaatttta gcttacttgg atcgccaaat
     2821 agtcaaaaat cctgcctctc cttcttcttc attcgtcaga gaagcctatc aggatagtta
     2881 taaacgcttt attcagccag caatcgagcg agaactgcgc aatgaattga ctgaaaaggc
     2941 agatgagcaa gcaatcgcta ttttcggcga aaacctccgt aatcttttgt tgcaaccgcc
     3001 actaaaaggt aaagttgtcc tgggatttga tccggcttat cgtactggat gtaaactagc
     3061 agtcgtagat gcgacaggga aagttttagc aatcgaagtt atttatcctc ataaacctgc
     3121 agcgcaagca aaaagagaag ctgctggacc agcttttatc caattaatta ataaatatca
     3181 agtagatatg gtagctatcg gaaatggtac agccagtcgg gaatctgaac tttttgtggc
     3241 tgagcagttg aaatccgccg accataaaac ctattacgct atcgtcaacg aagcaggcgc
     3301 ttctgtttac tccgctagcg aaattgcacg aaaagaattt ccgcatctac aagttgaaga
     3361 aagaagtgct gtttctattg cccgtcgcct gcaagatcct ttagctgaat tagtcaaaat
     3421 cgatcctaaa gctgtcggag taggccagta ccaacatgac gtttctcaaa aacgtttggc
     3481 tgaacaattg gattttgttg tggaaacagc ggttaaccaa gtaggtgtgg atgtgaatac
     3541 agcaagcccg cagctcttgc agcatatatc aggattgaat aaaacaactg cccaaaacat
     3601 tgtcatttat cgtgaagaaa acggagaatt caccgcacga actcaattga aaaaagtgcc
     3661 acgcttagga ccaaaagcat atgaacaagc aatcggattc ttgcgagtcc ctggtgggaa
     3721 aaacattttg gacaacacag gtatccatcc cgaaagttat tctattgcaa aagaaatatt
     3781 aacttcagtc caactttcag aaaaagagct tggtacagaa gaagcagtag aaaaattgac
     3841 acgattatcc gtagagaaac tggctgaaag cctatcagtc ggagaagaaa cgttagccga
     3901 tattttagct gggctgacac aacctggacg agatatgcgt gatgagatgc cagcgccctt
     3961 attacgtaca gatgtattga gtatggaaga cttgaaacca gggatggaat tgactggaac
     4021 ggtccgtaat gtcattgact tcggcgcatt tgttgatatc ggtgtgaagc aagacggact
     4081 tgtccatata tcgaaactca gcaaaaaatt cgtcaagcat cctacagatg tcgtgtcagt
     4141 aggagatatc gtaacagttt ggatagaaca agtcgatacg aaaaaaggca gaatcagttt
     4201 gacgatgctt tccccttatg aagagtaaca atgaggagta acaaaaattg acacaagaag
     4261 aactgcagca gttagtagaa gagatatcat taaaaagctt ccagcttcct ttcaagcacc
     4321 aagcaatgtt caatccacgc ttacgtacaa ctggcgggcg ctatcattta aacgatcatc
     4381 atttagattt taatgcgaag ctatttgaag agtcagacga agagacgatt gcaggaatca
     4441 tcaaacatga actttgccat tatcatcttc atctagctgg aagagggtat cagcataaag
     4501 atatggattt caagtatctt ttgaaaaaaa caggagggtt gcgctatgca ccagccttga
     4561 cgaagaaaca gataaagatg gagtattatc gatgccaaga ttgttctgcc acgatctgcc
     4621 gcaagagaag aatcgatgta cgcaaatatc gttgtggaag atgtcatgga gaaatcaaat
     4681 ggattgagac aaaaagagaa gactttaatg aagcacaaaa aatcagatga aaggatagaa
     4741 ggcctttgga aaaaagtgag cagaggaatc taaaagactg gaatcagcta ttaaattttt
     4801 tagccgcacc tgaagaggga aattttgagg aactgacggc acctacactt attttagctg
     4861 gaaactgtct tcctatctta gctgataaag cagcacaaat gtatttaaat ggccaagtag
     4921 atcaattgtt tttggtcgga ggggtggggc atgcgactag aatcctttat gagaattttg
     4981 aaaagcaagg atttcatttt gaagatggca tgagtgaaag tgaaatctgt cgtcagtatc
     5041 taaaagaagt ctatgatttg cccgataagg cttttctgat agaatcgaag tctacaaatt
     5101 ctggagagaa cgccactttt tcactggaga ttcttcattc cttaggagct gtaccagaaa
     5161 aaatcttatt gatgaatgat ccgacactgc aacgcaggac tcgagcaact tttgagaaag
     5221 tatggcaaaa tgaacaaact attttcgcga atgctgtgcc atttgtgccg gaaatccttc
     5281 acttttctga agagatcatc tttacagcaa aagaactgaa tcatcaatgg cctaaggaat
     5341 atttccatgc gctagtatta ggagaaatgg aacgtctcca tgacgatgag aacggctatg
     5401 gtccgaaagg aaaagatttt attcctcaca ttgatatatc agaggaagtt tggtcttctt
     5461 acaccagaat taaagagtca ataaaaacgg atttttctcg tacttgacca ttttagcaag
     5521 cgaatcctcc tttccaaata aatttggttg aaattttcaa tcgtttataa gataatgagg
     5581 agcgtgttga atgtaatagc taaaagaatg gacgctagat aagagaagag gattcaaatg
     5641 gaaaatcaaa ataaattgta tcattttgtt ggtatcaaag gttcaggaat gagctccttg
     5701 gctcttgttt tacatgaaca aggtctaaat gtccaaggat cagacattga aaaatatttc
     5761 tttacacaaa gagatttaga aaaagcaaat atcacgattc tgccatttaa cgcagataat
     5821 gtaaaaccag ggatgacgat cattgcagga aatgcatttc ctgattcaca tgaagaaatc
     5881 cagcgagcaa aagaattagg tttggaagtg attcgctatc acgactttat tggtcatttt
     5941 atccaaaatt atacgagtat cgctgtaaca ggctctcacg gaaaaacaag tacgactgga
     6001 ctgctctctc atgtattgag tggtgtccgt ccaacaagtt atctaattgg agatggaaca
     6061 ggacatggtg atccgcaagc ggaattcttt tcatttgagg cctgtgaata tcgccgtcat
     6121 ttccttgcct attcaccaga ctatgcaatc atgaccaata tcgattttga tcatccggat
     6181 tattatacaa gtatcgacga tgtatttaca gctttccaaa caatggctgg acaagtgaaa
     6241 aaagctattt ttgcgtatgg tgacgatgct tatttacgca aattaaaagc aaatgtgccg
     6301 atttattatt atggtgtcac agaaaacgat gatatccaag cacgaaacat cgaacgcaca
     6361 acttctggtt ctgcttttga tgtctatcat ggggatgaat ttgttgggca cttcactgta
     6421 ccagcattcg gtaaacacaa tatcttaaat gctttaggtg ttattgcagt agcttatttc
     6481 gaaaaactgg atctgaaaga agttgcagaa gaaatgctga ctttcccagg agtaaaacgt
     6541 cgattcagtg aaaagatcgt agcagacatg accgtagtcg atgattatgc gcatcaccct
     6601 gcagagatca aagcaacgat tgatggcgca cgccaaaaat atccagataa agaaataatt
     6661 gcagttttcc aaccccatac gtttacgcgt acgattgcat tgatggatga atttgcagaa
     6721 gcacttgatt tagctgataa agtttactta tgcgatattt ttggttcggc tcgggaagaa
     6781 caaggaaacg ttaagattga agaccttgga gcgaaaatca aaaaaggtgg agaagtcatc
     6841 aaagaaaata atgtatctcc attgttagat tatcatgatg cagtagtaat cttcatgggt
     6901 gctggagatg ttcaaaaatt tgaacaagcg tatgaaaaac ttttaagcag cacgacgaaa
     6961 aatgtactgt aatacaatta ctgcagtgtc cttataaaaa tagaaagagg gggagtggca
     7021 aaaatcttgc caagccccct tttttgcaac ttatgataaa cggtgttcaa aagcttgcat
     7081 ctgcggtaat aagcccaatc aaatcaaaaa catgagaagc tgttttttct tggctgttct
     7141 tattatttga tgcaggacag ctttttcacg acctctgtaa actataggaa tctgttaaat
     7201 caagggagca gaacttgcct tttacgctac ttttggtaca ataatgtatg attaaaaata
     7261 aactggaggg tttctatctt gaacataggt aagccgagaa aactaggaaa aacaataaat
     7321 gaaatcgagg aaggcgactc gttatcctta acagaatcta ttgaagataa ccagcttttg
     7381 ctgtatttgg gattgacgaa tgatgcaaat cctttgtata tccaacatga ctttgcacaa
     7441 aaaacagaat atcaacagcc aatcgttcca tcagtgatgc tgatggggat catcacaagt
     7501 gcaatttcaa agcatcttcc tggaccagga tcacatgttg tcaatttttc tgtcaatttt
     7561 attgaaccgg ttttccatta tgaaacactg acttttcagt ttgaggtcat aaaagtagat
     7621 aagatgaagg atgtggtgac gatttctgta gaagcggaga atacgaacga agatcgtgtg
     7681 ttggatgctg tcgttatggt ccaaccgcca caagttcctg aattggaaat agcaatcgaa
     7741 agtgaaggtg aattgaatga ataatccaag tacatcaatg tcaggtatca atcgttttta
     7801 tgcaaaagtt tatggatttt taggtatggg acttgccctt agtgcagtca cttcttactt
     7861 ggctctttgg gtatttcctt tgcaattagc aacttttatc aataattttc cactaggctt
     7921 tgtgggtctg tggatcgttg aactgatttt agtaatggtt ctaggcgtaa aagcacaaaa
     7981 gaatccgagc ttagcaatcg gtggatttat tgcctactct cttttgaatg gcataacatt
     8041 agcggttact cttgcatact acgatattgg aacagtaacg caagctttct tgacagctac
     8101 tttgatgttc atggggatgt ctgttgtcgg agtaacaaca aaaagagatc ttagcggggt
     8161 tggaagagca ggacaggcag ctttaatcgg agtgatcatt gcactagtct tgaacatctt
     8221 cattttgaga agtagcgtag ttgagctgtt catctcccta ctgttagtcg tcatctttgc
     8281 agggattaca gcttatgata accaaagcat ccgtaatatc tatgtccaga caaacggaac
     8341 agcacatagt ggaattgctg tattcatggc attgaagctg tatttggact ttatcaactt
     8401 gttcttggcg tttctgagaa tctttggacg gaacaactaa aaaagaaaaa aattcatcag
     8461 ttggggctat accgaattat ttggtatggt cccgcttttt cttttcgcat tccgcaggat
     8521 tctttgttag aatgaataag aactttacag taaggagtta agaagatgac aaaaaataaa
     8581 ttattactcg ttgatgggaa cagtgtggct tttcgcgcat tctttgcgct tcacaattct
     8641 cttgaacgtt tcaaaaatag aaacggtctt catacaaatg caatctatgc attcaatacg
     8701 atgtttgaaa atgttatgca aaaagagcaa ccgactcatg ttctggttgc gttcgatgca
     8761 ggaaaaacga cttttcggac agaaatgtat gcggagtaca aaggtggaag atccaaaaca
     8821 cctggcgaat tcaaagaaca aatgccatat atacgtgatt tgttgacagg actaggggta
     8881 cagtattacg aattgcccaa ttatgaagca gatgatatta tcggtacttt ggcagaaaaa
     8941 gtagacaaag atcaatttga tgtcgtcgtg ctttcaggtg atcgggattt gactcaatta
     9001 gctagtaaag aagtaaaagt ggatatcact gtaaaaggtg tcagcgatat cgaaagctat
     9061 acaccagaac atgtagcgga aaaatatgat gggttgacgc caaaacagat tattgacatg
     9121 aagggactag ccggagatgc ctctgacaat atccccggtg tgactaaaat cggtgaaaaa
     9181 acagctatca agctattgaa acaatatggc tcagtcgaag gaatttatga acatatcgat
     9241 gaaatgaagc aaagcaaaat gaaagaaaat ctgataaatg acaaagagca ggctttctta
     9301 tcgaaaaaat tggcgaccat caatacttca gcgcctgtgg atgtctctat cgactcattg
     9361 aagtatgaag ggaaaaatct cgataaactc gttccgtttt ataaagaaat ggatttcaat
     9421 cagttccttt ctaaattgaa tatcgtagaa gaagaagtaa aaatggatga tattttgttt
     9481 gaagtcgttc atgaattcaa agaggaaatg tttactacgg atatggcgtt gtacgtggaa
     9541 atgatgggcg acaattatca tacagaggaa atcgtcggag tagcgtgggg gacagaaaag
     9601 aaaatttatg tcacgaacga tctatctgta ttcgaaaacc gagcgttcca ttcttggatc
     9661 actgatccga ctcggctgaa aaaagtatat gatgcgaaac gaacttatgt tgctttaaac
     9721 cgctatactg gaaaaacgaa aggaatcgat tttgatgtct tgctaggtgc ataccttctc
     9781 gatacgaatg aaaaaagcac agatatcgaa ggaatagctg ctcattacgg atacaacgat
     9841 atccaatcag atgaagctgt atacggcaaa ggggcgaaaa aaggtttacc agaagaagag
     9901 gaactctttt ttgctcattt agcgcgaaaa gtagctgcaa tcaatgcgtt gacaccaaaa
     9961 ttgagccaag aactggcaga taaaaaccaa gaagatcttt tccggaaaat ggaactgcca
    10021 ttgtctatca ttttggcaga gatggaaata agcgggatca aagtagatgc gactcgctta
    10081 caagaaatga agggcgagtt ctctgctcgc ttaagagaga tcgaacaaaa aatctacgaa
    10141 gaagccggcg aagaattcaa tttgaattca ccaaagcaat taggagtgat cttatttgaa
    10201 aaaatgggat tacccgttat caaaaaaaca aaaactggat attccacagc cgtagatgta
    10261 ctggaacagc ttcgtgaaca agcaccaatc gtagaggata tcctcaccta tcgtcaaatt
    10321 gcaaaaattc aatctaccta tgtcgaggga ctgctgaaag tgatccaatc agatggaaaa
    10381 gtgcataccc gttatgtcca gacattgacc caaacaggac gattaagctc tgttgatcct
    10441 aatttgcaga acatcccgat tcgattagat gaagggagaa agatacgtca ggcatttgtt
    10501 cctagagaaa aagactggct gatttattct tctgactatt cacaaatcga gttacgcgta
    10561 cttgcgcata tctcaaatga tgaacatttg aaagctgcct tcctagaagg tcaagatatc
    10621 catgccagca cagcgatgcg tgtatttgga atcgaaaagg cagaggatgt cacaccaaat
    10681 atgcgtaggc aggcaaaagc agtgaatttt ggtatcgtgt atggcatctc tgattacgga
    10741 ctttcacaaa atctaggaat cagccgaaaa gcagcacagc aatacatcga tacgtacttt
    10801 gaaaaatacc caggtgtcaa agaatatatg gaaagaatcg tacgcgaagc aaaagaccaa
    10861 ggctacgtcg aaacgctgta tcaccgccgt cgatatctgc cagacatcaa ttcaagaaat
    10921 tacaatatcc gttcttttgc ggaacgaaca gctatcaata caccaatcca aggaagtgct
    10981 gctgatattt tgaaaatcgc gatgatcgaa ttggataaac gattaaaaga aacaggtctt
    11041 caagctacga tgctgttaca agttcatgat gaacttgtct tcgaggtacc ggaaaaagaa
    11101 cttgaatcat tagataaatt ggtgaaggaa gttatggaac aagctgtttc tcttcatgta
    11161 ccactgatca ctgacagcag ttggggaaaa acgtggtacg aagcaaaata aacattgttt
    11221 aagacagagc aatataatga aggtgaaaag aaaaaatgcc agaattacca gaagtagaaa
    11281 ccgttcgtaa aggattggaa cggttagtag taggaaaaac gattcaaaaa gttcaggtct
    11341 tgtggcccaa gatcatcgag caaccagaga cacccatctt tgaggcttct cttgttggcg
    11401 aaaccatcca atccattgga cgtagaggga agtttttaat ttttcatctc gatcattgtg
    11461 aactgatctc acacttgcga atggaaggaa aatatcaatt tacgaaagaa aatacaccaa
    11521 tcgataaaca tacgcatgta cttttctttt ttgaggatgg aagccaactt cgctacaacg
    11581 atgtacgaaa atttggtcgt atgacaatcg tcgaaaaagg agcaagtgca acttaccgag
    11641 gaatcatgaa attgggacct gagcctttgc cagatagctt cttattagca gatttcgcaa
    11701 atggactgaa aaagtcccac aaagcaatca agccattgct gctagaccaa cgtctagtga
    11761 ctggtctagg taatatttat gtagatgaag cattatggga agcgaagatc catccagaac
    11821 aaccggcgaa cacactgcgc cccaaagagg tagaacaatt acgtctatcg atcattgatg
    11881 ttttggatcg tgcaatagaa gccggaggta ccacgattcg cagttatttg aatgcattag
    11941 gagaatcagg cggatttcaa gtagcactgc atgtctatca gcaaactggc aaaccatgta
    12001 tacgttgtgg aacgccgatc gtgaaaacaa aagtggcaca aagggggacg cactattgtc
    12061 cgaattgtca aaggctaaaa atcgcaaagt aggatttgtt ttaggtttga cgggtggaat
    12121 agctaccggt aaaagtacgg cagccaaagt ctttcagtct catggatttc ctttgatcga
    12181 tggcgatgtg attgccagag aaactgttga gcctggaacg cttgctctga ggaaaattgt
    12241 atcagtgttt ggccaagagg tattgcagcc tgatgggcaa ctagatcgag ggaaacttgg
    12301 gatgattgtt tttccatcaa aggaaaaacg gcaaaaactt gatcagctat tagatccgtt
    12361 tatccgaaaa gcgataaaag atcaaatcgc ctctctaagt tccaatcatc ctttagtaat
    12421 tgtagatatc ccattgctct acgaaggtca ttatgaccac tatatggatg cagtagctgt
    12481 cgtttatact acgccagaaa ctcagcttca gcgtttgatg aaacgtaatc aactgacgct
    12541 agaacaagcg cagcagagaa ttagtagtca acttccaatc gaagaaaaaa agcagcgtgc
    12601 ggatattttg ttcgacaaca atggaacaaa agaaaaactt gtgggacaaa tcgaaaattg
    12661 gctttttgct aatcgctttc tttgagtatc tgtgtcaatt ttgctatcct gagtatatag
    12721 aaagtgaggg atagcgatgg gatcattaaa aaatcaaaag gataaagtcg taggtaacgc
    12781 aaaagaaaaa atcggcgaga tgctcaataa agaaaatcta atcgatgaag gtcgtacgca
    12841 atcagaaaca gcagaagaaa aagaaaagca gtaccaagca agaatcgatg aaatagaaga
    12901 ccagcaggca gaagaagaag cgaagcggca agatttgact caagaacgaa aaaatccgac
    12961 acctgatcgt agtaaaacac cgctcccaga aagtgaccac atttccgatg agcaaaaaat
    13021 cgaggaacag cgaatgaaac actatacagg aatcgaagag aagttataaa atagtaaaaa
    13081 atcgagatgt gacttgaagc agatgagaag gtgttcatct gcttcaagtt ttttgtgcta
    13141 gatgactaaa tcagcttttg tgtaagttat ttctcagtaa tcaaggtgat cagtattgga
    13201 aaattgaaat ttagtaagga caggggacac aattacgcat gaaagtagaa aaaattgttc
    13261 ttatatccgt gttttttggg taggacagtc gcgtttgtga tttgtttcgt gttataatac
    13321 aactagttgt aaagaaagac acatccttta tataaaatgc gatgcaagag gtgagacaaa
    13381 atgagatgtc ccagatgtca acataataat tcacgagtaa tcgacagccg tcaagcagat
    13441 gatggacgtg cgatccgtcg ccgtcgcgaa tgtgagaatt gttcgttccg attcactaca
    13501 tttgaacgaa ttgaagctgc tccgttatta gtaatcaaga aaaacgggga acgcgaagag
    13561 ttcaatcgcg ataaaatttt aagaggactc atccgttcag cagaaaaaag acctgtagct
    13621 atggaacaaa tggaacaaat cgtcaaccat gtcgaaaacc gcgtacgcag tctcggagaa
    13681 aacgaagtat cgacgaatct aattggtgaa tatgtgatgg aagatttagt tgatttagac
    13741 gaaatcgctt atattcgttt tgcaagtgtt tatcgccagt tcaaagatat gtctgttttc
    13801 ttaaaagagt tgcaagatat cgtggataaa gcaaaagaaa ataataaaga gaataataaa
    13861 gaaaacaatt aagaaacaaa aaggaggcat ttccttggaa aatgcttgga aagagcttca
    13921 accaaaaaat atttaccaag gaagaaaagc ggctccgctg agagaagaca gcaagaacgc
    13981 cttgctgtat ctttatcagc cactaatcgg cggagaagcc ttgagtatct atttcaccct
    14041 gttatcagaa atctctcaag aatctggcaa aggtcctgaa gggatgcatg cagatctgct
    14101 tagtagtcta ggctgcggta tcccgcaatt ttatgatgca agaaaaaagc tagaaggaat
    14161 cggcttactg gatgtttatt ttaaagaaga tagtgatctg ggacctcgtt ttatttatga
    14221 gctgttagaa ccactcattc ctaaagcatt tttcaaagac tctgttctgg cttttcttct
    14281 tctggaaaaa gttggtgaac gacgattcca gaagcttacc caattctttg aacctaaaag
    14341 gcatacagca gagggatatc aaaaaatcac aaaaaaattt ttagatgttt atcgcttcaa
    14401 tgaagcagtg tacgctgcta atcaagaaaa catcgaatcg ctgaataaat cttttgaaga
    14461 atctgaatca gtagcattac ttgaagcaga ttcgacattc gattggcagt ttttgaatga
    14521 ttggctggca aaaaaacata ttgcaagtct tgatgatcca atcatcaaac aagtcgacat
    14581 gtatcatcag ctttacggtt tcgatgaatt gacacttggc gaactgatca gtcaatctta
    14641 tgactttagt gaacaaaaag tatctgaaaa agaactgcaa aaagccattt tggcaatgca
    14701 gagacgtccg gtgaagcaaa caaaagaaac agttgcggtt tctgaaaaca gtaatgaacc
    14761 ctcgtcaaac gaacatttga caaacgcagc gcttcagctg ataaaagaag cacagagcat
    14821 tccaccgatg aaatatctgg aagcaatcaa gtcagaaaaa ggcggatatg tttctaaaca
    14881 agaaaactgg ttactgcaag atcttgtttc tcaatcaggt ctttccagta gcgtgatcaa
    14941 tgttttgctg aattatgtac tagtgatcaa gaataatgct agcttaaatg ccagttatgt
    15001 aaatacagtg gcaaatgaat gggcacaaaa gaaaatcgcc acagcagaag aagcgatcca
    15061 gcacattcgg caaataagta atcaagcaaa acaatcaaaa caaaagaagc aaacaaatta
    15121 tcaaactggc aagcgaaatg ttcgacggga aaagcttcct gattgggtca accagccaaa
    15181 agatgaaaaa cagatcagca gcgagaaaaa agcagagatt gaccgccgtt ttaaagaata
    15241 cctggcaaaa aaggagggtg atatctagtg gaagacgtag gcaaagaatt gaagaggatc
    15301 atcagcaaac gcaattatca agaaaagtat gctgaaatga tcgctgaagt cttaaatgat
    15361 gcggatgttc aagcttttct aagcgcacac caagaagaat tgacacaagc ggatattgaa
    15421 aaaagttacg ctaaattgta tgaattcgtg caagaaaagc gtaaatatca aaaaaacgat
    15481 ccaacgatga tcgctcccgg ctatgagccg aagctgacgt tgaattttca ttatgtggat
    15541 gtcacttatg taccaacgga agcattgtta gcacggcaaa gacaagaaga aatcagaagc
    15601 cgagtaaaag caatggatat gccaaaagat attcaatcgg cttcttttga aaactttgaa
    15661 cgtacagatg gacgaggata tgcgagctta gaagccctag attttgtaga gaaatatact
    15721 gctgatccaa aagggtatca taaaggactg tatctagtag gaagttttgg tattggaaaa
    15781 acatatttat taggagcaac agcgagagaa ttagcgattg ctggattcac cacgacgcta
    15841 gtccattttc cgacatttgc cgttgagatg aaacaggcaa tcggaaaaga tcaagtggca
    15901 gaaaagttag atgcagtgaa acgttcacct attttgatga tcgatgacat tggtgcagat
    15961 gcgatgagta gttggatacg agacgaagta ttcggtgtta tccttcaata tcggatgcag
    16021 gaacagttac caaccttctt ctcatcgaat tttacaatgg atgaattgga acagcatttg
    16081 tccgtcactc aacgtggaga tgaagagccg ctaaaagcga aacggataat ggaacgcata
    16141 cgttatttga caaaagaaat cgaaatgact ggtcgcaacc gacgcaatgg ttgaacagtt
    16201 gacaagtcca actgacattt gacctagtag taaaagcagg tcagcgaatc attatatgga
    16261 cagaaatgac cggagacaat caccgcaaca agtaatgcag aaacttaaac ggaggatttt
    16321 ttatgagggc tattttttct agtatatctg tagttggtct attttttctt ttagcaggct
    16381 gcggtagcgc agatagcaac acaggttctg ttgattcgat tgatgcgggt caaacagtaa
    16441 aaacaagcag tacgaaaacg gagagacaaa gcatatttgt cggaacgatt gaaagtatta
    16501 ctcaagtaga agcagaagaa gaaacgcttc agttgaaact cgtcgatgtc atggccaaag
    16561 aagatccagc gaatatggga acgtcattca gcaatgacgg agtgatctta aatgctactg
    16621 ctgaaaaaat aagcgtggac ataaatgaat tgaaaatcgg tgacaaagtc caatttacat
    16681 tagttgagat gccgatcatg acgatgtcta tcccaccgca agttcctgga gattcgatta
    16741 ttgatgtttc attgaacaaa taaccaataa cattttttca aaaataagaa aatgttgttt
    16801 tatagaacga aaaggtatat tttttaagga gatatgggaa ttt
//
LOCUS       DAFEIE010000055        16526 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFEIE010000055
VERSION     DAFEIE010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.057"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(143..418)
                     /locus_tag="LP345_002055"
     CDS             complement(143..418)
                     /locus_tag="LP345_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBL1760829.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(661..1971)
                     /gene="der"
                     /locus_tag="LP345_002056"
     CDS             complement(661..1971)
                     /gene="der"
                     /locus_tag="LP345_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBL1760830.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2153..3382)
                     /gene="rpsA"
                     /locus_tag="LP345_002057"
     CDS             complement(2153..3382)
                     /gene="rpsA"
                     /locus_tag="LP345_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBL1760831.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3516..4196)
                     /locus_tag="LP345_002058"
     CDS             complement(3516..4196)
                     /locus_tag="LP345_002058"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBL1760832.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4245..4880)
                     /locus_tag="LP345_002059"
     CDS             complement(4245..4880)
                     /locus_tag="LP345_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1760833.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4946..6349)
                     /locus_tag="LP345_002060"
     CDS             complement(4946..6349)
                     /locus_tag="LP345_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBL1760834.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6336..7367)
                     /locus_tag="LP345_002061"
     CDS             complement(6336..7367)
                     /locus_tag="LP345_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760835.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7398..7619
                     /locus_tag="LP345_002062"
     CDS             7398..7619
                     /locus_tag="LP345_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBL1760836.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7784..8521)
                     /locus_tag="LP345_002063"
     CDS             complement(7784..8521)
                     /locus_tag="LP345_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBL1760837.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8674..10014)
                     /locus_tag="LP345_002064"
     CDS             complement(8674..10014)
                     /locus_tag="LP345_002064"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBL1760838.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10251..11774)
                     /locus_tag="LP345_002065"
     CDS             complement(10251..11774)
                     /locus_tag="LP345_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBL1760839.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12152..12763)
                     /locus_tag="LP345_002066"
     CDS             complement(12152..12763)
                     /locus_tag="LP345_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1760840.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12886..13011)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13093..13809)
                     /locus_tag="LP345_002067"
     CDS             complement(13093..13809)
                     /locus_tag="LP345_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL1760841.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13815..14384)
                     /gene="scpB"
                     /locus_tag="LP345_002068"
     CDS             complement(13815..14384)
                     /gene="scpB"
                     /locus_tag="LP345_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBL1760842.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14368..15165)
                     /locus_tag="LP345_002069"
     CDS             complement(14368..15165)
                     /locus_tag="LP345_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBL1760843.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKGEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15135..15506)
                     /locus_tag="LP345_002070"
     CDS             complement(15135..15506)
                     /locus_tag="LP345_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL1760844.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15525..16412)
                     /gene="xerD"
                     /locus_tag="LP345_002071"
     CDS             complement(15525..16412)
                     /gene="xerD"
                     /locus_tag="LP345_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBL1760845.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4646 a         3577 c         2798 g         5505 t
ORIGIN      
        1 ataaaaatta aataaaatac atgtgttttc tatgtatgac atacggattc ggaatctctg
       61 tctcttattt attccttttc tgctaggaaa taaaaagaaa agcacttgta gccctagagc
      121 cacaagcgct ttttcaactg tcttatttaa cagcgtcttt taatgcttta cctggtttga
      181 atgcaggtac tttgctagct ggaatttcga tttcttcacc agtttgtggg ttacgacctt
      241 tgcgagctgc gcgttcgcga acttcaaagt taccaaaacc gattaattga actttttcgc
      301 cgttagctaa agcatcttga atagttgaaa atacagcatc tactgctgca gttgcatctt
      361 ttttagttaa atcagtagct gaagcaactt tttcgattaa ttctgctttg tttgccatgg
      421 atagattcac ctcctccaca agagatatga tagaaatatc atttagttaa aactttctga
      481 gtggtccaga agtttaaaaa gaaatattga ttaacttcaa tattctgtta tcacgatatc
      541 atatgaaccg cttaatagca aggtttttac caattttcac atgctttttt tagtcataga
      601 aacgtaacaa acgaaactgt ctttttcttt tgaaaaaaaa acgtcgatat ggtaaaatgc
      661 ctattttctc ctacgaggga taattcggat ggacgtccct tcaaaagtaa atgcttttct
      721 gatttgattt tctaagaaac gttcataaga aaaatgcatc aattcctctt cattgacaaa
      781 aacgacaaat gtaggtggtt tgacagcgac ttgtgtagca taaaaaatct tcaggcgttt
      841 tcctttatct gttggtgttg gattgattgc tacagcatcc ataatgatat cattcaacac
      901 agccgaagag atacgaagat tctggttcat acttacttgt tcgatcattt caggcagacg
      961 ttccaaccgt tgtttagtca ctgcagaaac aaaaacgatt ggagcgtaat caagataccg
     1021 gaattcatca cgaatctctt gttcgaaatc acgcattgta ttggtttctt tctttacaag
     1081 atcccattta ttcacgacga taataattcc acgaccagct tcatgggcgt aacccgctac
     1141 tcgcttgtct tgttcccgaa tcccttcttc agcattcagt accatcaaaa cgatatcaga
     1201 acggtcaatg gcacgcattg cacgcatcac gctgtatttt tcagtatttt cgtatacttt
     1261 tccgcgttta cgcataccag ctgtatctat cattaagaat ttctgaccac tttcagaaac
     1321 gaagtgggtg tcgattgcgt ctcgggtcgt tccttcaata tccgaaacaa ttacacgttc
     1381 ttctcctaaa atcgcattga tcaaagagga tttaccaaca tttgggcgac caatcaaact
     1441 aaacttaatc gtgtcgtcgt cctcttcttc agtctcttca gagaaatact tcactgcttc
     1501 atctaaaata tcaccaatcc ctagtccatg gcttcctgaa acaggataag gatcgcctag
     1561 ccctaaggaa taaaattcat agatatcgtt tctcatttct ggattatcta ctttattgac
     1621 tgctaaaatc actggtttat tacttctgta taaaattttc gcaaccatct catctgcgtc
     1681 tgtcacgcct tcgcgtccgc tgactacaca aatgattaca tctgcttctt caatcgcgat
     1741 ttctgcttga tgcttgatct gatccataaa aggttcatcg ccaagatcaa ttccgcctgt
     1801 gtcgatcacg ctgaattctc gacctaacca ttcacctttt gcataaatac gatcacgagt
     1861 tactccagga gtatcttcga caatcgagat acgctcacca gcgatgcggt taaaaatcgt
     1921 agacttaccg acgttcgggc ggccaacgat tgcaattgtt ggatttgcca tattatttcc
     1981 tcctcacaag tttccaatct cacttagttt aacgaatgca ttgccaactt tcaagcatag
     2041 attgtcaatt aaacgaagta tttttattcc ttattgaaat actaatcgct tttcaaaaga
     2101 aaaactgaga caaaagcagc tgctttcatc tcagtcacag atacaaaatc aattattttt
     2161 cagaatcatc ggttgctttt tcttctactt cttctttcaa cgcatcacct aaaatgtctc
     2221 ccatagtaaa tccagtattt tcttctggta attcataaga ctcaacattt tttggttctt
     2281 cttctgaagc tggtttttct tctaaagctt tgatactcaa tgcaatacga tgttcttctg
     2341 gatggatctc taatactttc actttcactt cgtcaccttc atgaagcact tcatgtggtg
     2401 tcgcaatatg tttatgtgaa atttgagaga tatggactag cccttctact ccagggaaca
     2461 cttcaacaaa ggcaccgaag cttgtcaaac gtttaactgt tccgtctaat actgtgccaa
     2521 ctggagcttt tgtatcgatt tctgaccaag gtccaggctg tgtgtctttg attgacaagg
     2581 aaacacgttc ttgttcagga ttgatagaca acactttgac atttacatca tcattgacag
     2641 ccaatacatc acttggtttt gctacatgac tatgtgaaat ctctgagaca tggactagac
     2701 cgtcaattcc gcctaggtcg acaaatgcgc caaaatcagt aagacgtgca acacgtccac
     2761 tgagaacatc tccctcatgg atagttgaaa gaatttcttt tttcttttct tctctttcgt
     2821 tttccactac cgctttatgc gataagatca aacgattttc tgatggttcg atttcgatga
     2881 ttttaaagct caatgttttg cctttatagt ctgaaaagtc tgcaacaaaa tgatcttcca
     2941 ccattgatgc agggacaaaa ccacgtacac cgacgtcaac gactaaaccg cctttgacaa
     3001 catttgtaac aggtgcttcg atgaccttgc cctcttggaa atctctttcg atatcttccc
     3061 aaactttttt agcatctaaa cggcgttttg aaagtaggta gctgccgttt tctttatctt
     3121 tgccgatcgt actgataacg actaaatcta atacatcacc gacttttact acttcgctga
     3181 tatcttctac cggcaaagtt gataattctt ttgccggaac gactccttca actccagccc
     3241 cttcgattcc gacaatcact tgtttgtctt caatgactaa aacttcgccc ttaacaacat
     3301 cgccaacttt tacttcttgt acgcttttca ttgcgtcttc cattgactgg ttgttctctt
     3361 gattttgatc aaattctgtc ataacacttg tcctcctaac caacattctg ccgtaagtac
     3421 ggtactgttt ttagtttaat tgattattca aaaaaaataa agcgatttcg ttcgttttcc
     3481 ttgaaaaaac aattgttttt catttttttc ttaatttaaa aaagaagata accttttttc
     3541 aaaacaacag cttttattgc tgcaacgact tctggaatcg atttgccagt cgtatcgata
     3601 cgaacagcat cctctgcttg cttcagcgga gagacgtccc ttgttgaatc ataatggtct
     3661 ctttcctgta tctctttcgt cagtgtttca agatcagtcg gaattccttt ttcttggttc
     3721 tctttgaaac gtctttctgc acgctcactt acgcttgcta ctaaaaagat tttcacttct
     3781 gcattcggta atacagctgt cccgatgtct cttccgtcca tgacaacgcc accgcgttcc
     3841 cctatttttc gttggacagc aactaattct tctctgactt ttccatgtgc agagacttca
     3901 gaaacagctt ttgtgacatc tggttgacgg atttctaaag tcacatcttt tgatgctatg
     3961 aatacatgct gtccatcttc ttgttgcgaa aaagagatag gatacttttt gatcagcgaa
     4021 actagccctt cttcatctga aaaagataca ttgttcgtaa tagctaaata agttactgcg
     4081 cgatacatgg caccggtatc tgtataaata taattcaatt cttttgctaa tatcttggca
     4141 acggtacttt tcccagatga agcaggcccg tcgattgcaa tactgatttg tgtcatgata
     4201 taactccttt ttctcagaaa aaaagccgca aagcgcggct attattattt aattcttaat
     4261 tcttgaccag ggtaaagcat aaagttgttt ggatctaagc cattcaattc aaacaattga
     4321 tcagtggtga tccctgcacg ctcagccact tgttttggac cttcgcctgc ttgaacagtc
     4381 gttgttgaac cggctgcagc tgatgaagaa ggtgttgttt ctgctgcatt gctgcttgaa
     4441 tcccctgctt gataagttgc ctcacttgag gaagtcggtg ttgtctctgc tgcaatactg
     4501 ctttctgacg ttacacctgt atcttgagac acagtagatt cttccgcgat tgtactagat
     4561 tctactgttg aagtctcagt tgactcctct tttgttgtac ttgtagaact ttctactact
     4621 gatgtcgaag tttcagaaga agttgctgct gttgcattgt tgcttgatcc atttctgatc
     4681 cagaaataag cacctgctgg aatagcgata cataagacca gtaaaatcaa aaatagcgaa
     4741 agaaataatg tatttccttt cttttgttgt ctctgagaac ttcttgatga aacttcatca
     4801 tctgtatcgt agattggttg ttcccatggt tcttgtgttt cgttattttc tgtagattga
     4861 tgtctatctt ttctgctcac tgttttacct cctaaactct atcgtgtgta ttataccata
     4921 ggaaaaagtg tcttgtccta aaaaatcaat gttccatgtt ttttttaaat aaatttagta
     4981 aaatcgtttc ccaatgaagt tgttcagtct tagaaaaaag cttcctcttt ggcagaagtt
     5041 ctgcttttgc tccatcaata tcacaacaat tctgcggctt ttcggagagt ttttcgccaa
     5101 aataagctaa gatgaatttt ctgcggcagt tttcttcatt aatatagcga agcatctgct
     5161 gcaggcggaa ttctttttct ttttcctgac gtttgagccg ttccacccaa ttttctggtt
     5221 tttcagactg ctggatcagc tccatccatt ttttttgcag ctcatcaaag ggagcttgct
     5281 ttgtggcata ttccaaataa agctcaaaac tttgtcgctg ttctctagaa agttgattaa
     5341 agaaataatg gatacgttca tccccacttt gataaaaaag aattgctgca ctttcttcct
     5401 gatctctgcc tgctcgaccg atttcttgta catagttttc tagactgtct ggcaaatcat
     5461 aatggaccac ataacggata tcagatttat cgatccccat accaaatgca ttcgtagcaa
     5521 tgagaaactg cagctgattt tttacaaact gctgttgaag ttgtcttctt tgagctgcat
     5581 caagaccacc gtgatagtat ccaactgtaa aacgttccct gaataaatga tacaatcgtt
     5641 cgacttcttt ttttgttgca caataaatga ttgccgctcc ttgtgctctt tccatgaagt
     5701 gttcaagttc ttgttctttt tgctgcgttt tccgaacaaa aagcgagata ttttgccgat
     5761 tgactgattg tctgatctct tttggtggtc gatcaaatag tacatgacgt atatctcttg
     5821 ctactaaatc tgttgctgtc gccgttagtg ccagtgtgac cgggtttcct aaaagctttc
     5881 ggatttttcc taactgttga tattctggac ggaaatcaac tccccattga gacacgcaat
     5941 gagcctcatc tactacatat aacgcaatat tttgtttttt cagatgctct aaaagagaag
     6001 gattagtcaa catttcggga ctcaaaaaca aaaatttata ttgcgataga tgacggagga
     6061 cgtatcttct ttcagattgc gaaagtaaac tattgaaagc agctactcgt ttctcccctc
     6121 gtttttgtaa ttgcgtcact tgatcttcca ttagagaaag cagcggtgac acgatgatga
     6181 ccagaccttc cattaaatac cccgtcaatt gatagcaaag gctttttccc gttcctgtag
     6241 gcaaaatagc gagagtatct tctccatcaa gcaacgcctg aataatttct tcttggccgg
     6301 gacgaaatga atcaaatcca aaatattttt ttaattcatt tattaacatt ctgtatcgct
     6361 tcctttctca atagatagat ttgatacaaa cgaaattctc cataatctaa ttgtccatct
     6421 acattccatt cgctaaagcg ccactctcgc acggaatcct tatttggttc caaacgttcg
     6481 attgtttctg cagagagaat ccactcgtat ggaaaatcat caaaaaacaa ggcccactca
     6541 ataagatgat ctgttactgt tcctcttttt aaatgacgga ttgccatgat ctggtcaatt
     6601 gtctgaccat tcataaacat ctgcttggtg atcatcatgc tttgattgaa attttgctgt
     6661 aataatgaat cgatcaaagc gtgccaaagc gaatctggcc gtttttcgat ttgtgctaac
     6721 aaaaggtgga tacatctgct ttgttgcaga taaacctctg actcatcatt gttttttgcc
     6781 agctgataag gaagcagccc tgttcgctca tttccagata attggttagc taaaaaatct
     6841 gctgcttctt ctggtatctc cgaaaacagc tgcaccaaac tctcatacgc agtatcaatc
     6901 aaaatttcac gtggcaattg gctttcacta agccattttt ttagttggaa agtataaaaa
     6961 ggacttgtct ctgctggaag atagtcttga atacccgttg ccagattaga aattacttga
     7021 acagcaaatt taatgagccg ccaactagtt tcccctgttc tgccatagcg gtcaaaacgc
     7081 aaaccagtat gttctatttg atgttcggac aacatatcag cccctgcagg cgttagcttt
     7141 gcttcatttt catttatttc gatccaacct tgctgcgcaa ttttttgcaa aatttgataa
     7201 aacttatcct gcttcaattc tggaaaactg ttatggataa acaaaagttc gtgggtaaat
     7261 ccataaataa gtactgaagt cgttcgtttt cccacaagga gttggtaaag agaactaatc
     7321 cgcagcttgt gtcctgatga aaatagcgat aaaataaaaa caatcatatt attctcctta
     7381 agttaggatg gttagaaatg tcactactat gtaaacttgt acctgaacgc tgtattgcat
     7441 gcggtctttg tcaaatcgaa gcgccagata ttttcgatta tgatgaagaa ggaatcgttt
     7501 tatttgccca agaaccagag gctcatcaac agttcgtgat gccggaagaa gaaacatatg
     7561 taaaaaaagc gtatcaaaaa tgtccagttc gagcgatttt attagaaaat aaaatataaa
     7621 tataaacgaa actttaaaaa cgtacactaa gttctctaaa cttgaaaata agccgggatc
     7681 tgtttctctt gttccgtgaa atcccgactt attttgaaag attcatttgc tatctatagt
     7741 taattgacta gttttttcac ggaccctata ggacccattt atattatttc aactttttca
     7801 gccagttttc caatgtattg acgatcacag tttgctggtc tgcgttagaa atttctgcct
     7861 ctccatctcc tttttgctca ccatagctgc caaaacctcc atgatttccg ccattgattg
     7921 atacatactc tgttctttcc ggtaaatact gcttagcttc ttgataagct tcctgattca
     7981 atactttatc ttttgtcgcc gtgatcgata aaacaggaac agctgattct gtcaatgttc
     8041 cttttttgtc gggataactt gccatgaaga ataccccttt taaatgtttg tctgaatgat
     8101 tcttattgac ataacgactt gccattacgc cacctaatga atggccaccg atcacataat
     8161 cggaatttgg aaaatcttct ttgaccttat ccgctttgtt tccgcccatc actgctagat
     8221 caagtggcat tttgacaata gcgactgaaa agccgttttt tgctaaatct tgcgcccaaa
     8281 tactataact ttctggctct acgagagcac caggataaaa aataagtaat ggagactttc
     8341 catgattctt tttctctcct tcaaaaaata agtaatcttc tttgtttttt ccttctttta
     8401 ccaacacttg cgcttctgac gatggttcgt acgtattttg ctgtatatag taataaccgg
     8461 ctccaccgag taatcctaaa atgatgacta agccaattag tattcgtcta aatattttca
     8521 ctttctccca ccttttctat ctgagtgacc cctttttctt aatcaagtat gattatacct
     8581 taaaaaaata agagagaaat gcaaactttc cagcatcaaa taaaaaaaga cggaatatcc
     8641 atttgaatat ccgccctttt tgtatgttta tttttattta gcacataaac gatacacagc
     8701 ttctgcataa atttccattg ctttatacat actacttaat tcccatcgtt cattcgcctg
     8761 gtgcataaag tcaggagtat cagggaacat cgcaccgaat gccacacact ggttcatcgt
     8821 acgagcaaaa gtagcgccgc ctgatacaaa cggttcagtc atgtctccag taatatcgcg
     8881 atatgtcccc aatagatttt tcactaactc actgtctagt ggcacgtata atgaatcaag
     8941 gaagtcaaat tcttcataag tcaacccata tttttctgct gttttagtta atttagctac
     9001 taaatcatct ttcttgaatg taacagggat tctcatatct acaccgattt ttgtttgttc
     9061 tggtgtgatt tccaaacttg caaagttcat cgttagctcg ccggattgtt catcttctgt
     9121 tttgcccacg acagcttcac cagttgcatt ttcttgaact aattttccta agaaattgat
     9181 tgggccaaaa tcaaatactt ctgaaagagc aattgccaga cgagaaatag cattcactcc
     9241 ttgtgctgca tctttcgcgt ggatactttt accaagaacg acgatgcctt caccttgttc
     9301 ttcgaaatcg aattcgtgtt ttttcaatgc ttcttttact tcagaaagct tttctccaga
     9361 gtaaggagct gcatcaggaa caacattcaa cgctcctcca gcttttacag aaaactcgtt
     9421 cgttcctggt cctgtcaagt aagcttgcaa taagcctttt tctgcataaa ttaaaggaaa
     9481 ttcagcatct ggcgcaaatc cttgcgtaat tccttcttct ttttcgttat atttttctaa
     9541 acaacgccat aaattttctt catctgtacc aaagataaaa cgaatacgtg tcttgaattc
     9601 cacgccagca tcaatcaaag ctttgacggc atacattgcc gcaatagaag gacctttgtc
     9661 atcttgggat ccgcgaccaa ctaaccagcc gtcttttata gttggatcga atggttttgt
     9721 ttcccaatta ttttcgtccc ctgctggaac aacgtccata tgacacaaga taccgaataa
     9781 ttcatctcca gagccaatct ctgaataacc gtaatagcct tctggatctt taaatgttct
     9841 aaatcctagc ttttcactga tttccaatac tttatccaaa gcttcaatca cttttttacc
     9901 gaagggatgt ccttgtcctg aatctgcttc atctagtacg gaaggaattc ggatcaattc
     9961 gctcaatgat tctaatgctt gttcatgatg ttgttctgtc acaaattttt tcatgatatt
    10021 atcctcctaa tatgttaaaa agggtcatgt caaattcctc cgacacaacc tcttcttctc
    10081 aaataatgac gttttaagcc tgctccatca gcaagcagaa tgttcttaac aaatgatgaa
    10141 agaaaaaaca ctcactgaat ggagctattg acttgtccac gtgcttatcg atagccgttt
    10201 atcggtttct tcattcttat gatagacctt gtacttgtat ttgtctaggt ttagaacatt
    10261 gctgctacac ctaggatcac acagatggct acaaataata tcgcaattaa tttaccggta
    10321 aatttccacc acactgaaac atcgaaacga gcaattgcta cagcacccat tacgatagca
    10381 gatgttggtg taattaagtt tactaaacca gatgcagatt gataagcagt gattactaaa
    10441 tccttaccga cgccggcaaa ttcacccata ggtcccatga ttcccattgt tgcagcagct
    10501 aagccggaag ttgaaggaat caagaatgac atagggatat agaaaataaa tgtaataatg
    10561 atgaatacac ttgaagataa tgaacttaat ccttgttcgc cccaatgtaa gatggtgtct
    10621 gtgattaatc cattgttcat aaccacttgg ataccacgag caacagctac tacgattgct
    10681 acaccgatca aatcagaagc accagctaaa aattcagaga caaattcaga ctctttcatg
    10741 ccataagtga ttgctactac gatggacatt actaagaata acatagtaat ttctgggaag
    10801 taccagtcac ctaatggaag catgctttta cctagaaccg tacctagtac cggaaggttt
    10861 gttaaccagt ttgtcaatga ttcaaaaatc gtgaaattcg cattcaaggt tgtccaagga
    10921 atcaaactga tgatcatgat accaaaagta ataaagaaca atacattaac atgtttttgt
    10981 tttttcgtga ttacttcttg acgaccgatt gcttcaatat cgaaatgctt catatcttct
    11041 ttacgttggt tgtatactaa tgattttgtt ggatcttttt cgatctttga tgcataacga
    11101 tacacatata caatagaaat agctaacaaa ataacgaaca tcaagaatcg aagaccaata
    11161 ccttcaccca tcgaaatccc aacagcttgt gaagctacgc ctgttgcaaa aggatttacc
    11221 gttgaagcta gacagcctac ttgagaccct actaatacga ttgctacagc tactactgta
    11281 tcaaagccta cagccatcat gactgggatc agtaaagcat agaatggaat cgtttcttct
    11341 gccattccgt aagtagagcc gcctaatgca aataacagca tcaatactgg aataagcatt
    11401 ttttcttttc ctttgaattt cttcacaact gaagcaatcc cggcatctag tgcccctgtt
    11461 ttgttgataa tacctaaaaa tccaccaaca accaaaatga agaaagagat tgggattgca
    11521 gcaggtgttt ctttagttag ctcccccgct ggtacaccta gcatcccatt gattggcgcc
    11581 atgaaaatat cccacagccc ttgaggattt tgttgtactc gttcatatga tccagcgacg
    11641 atgttgcctg catcgtctac actatagtgc ccagctggta taaaccaagt aagtacagcg
    11701 attactgcaa taataataaa taagaccgta tacgctgaag gcatttgaaa ttttttcttt
    11761 tttgtttgtt ccatcttctt cttcctttct tttccgttag agacaacaat tttggctcta
    11821 atgttatttt atcaaaaaga gtatcagaac aaaaataata acacgcattt tgtaaaactt
    11881 ttgttcaaaa agttcgtttt tccctattcc ctcctctttt ttcaggtttt taaagctttc
    11941 ttctttttca ttgtagcgtt tccttttttt tataaacaaa cattttcgtc ttttaaaagg
    12001 agaagaattt cacatttgca aagaattgat tgatttttat gcataaatca aaaaaatact
    12061 caaaacaaac aaataaaacg tttacattat tgcatgtctt gtattttttt ccaaaaaaaa
    12121 agaccaagaa atttcttgat ctttttgata tttatttgac tgctgtatga cgttgttcga
    12181 actgatgttg ttttcgactt aaccatggaa gaagttgcgc atgcagcact aaaaagacag
    12241 cactcacgat gaatcctttg atcaagttga aaggaacgat cccaatcagt acatagtttg
    12301 ctaaagacat gcccagcatc tgtgttgcgt tcagccctaa aaacattaag taaagaggcg
    12361 taataacgaa ataatttgcg atactcataa aaatagttag agcgatggtt cctgtaatga
    12421 cacctaaaaa tttgtttctt cctttatgct gtttctttac actaaagaaa taataaatcg
    12481 ggaatgtaaa gatcgttgtt gataagaaac tagcagtgtc tcctaccaaa ttatccggag
    12541 aaaaacctgt agtcagcaga tgtaatactg aacgcaagaa cgctgttgca actccggccg
    12601 ctggaccgaa taagaacatg ctgatcaata ccgagatatc actaaaatcg atcttcaaaa
    12661 aactaaaagc cggcatgatc ggaaaagcaa aatactgtaa aactaatgcg atcgcagcaa
    12721 acatcgctac tgcaaccatt ttctgtacac gggtgttctt catttgaaat cctcctgtta
    12781 ggactcctct tcagcgaact ttttgacgtt tctctccaaa tgaaaaaact ctattttcca
    12841 gggaaaatag agttagagtt atttgatcaa gcgtcgtcaa ataagctcta tcttctttat
    12901 ccagactata ctgtcggtat cggaatttca ccgattcagc tatttttttg caaaataggt
    12961 cgtggactat aaccaccggt cgggaatttc accctgcccc tgaagacgaa ccttatataa
    13021 tttttgttta catattcatt atacatatct attcaaaaaa cgcaacatct aacacttata
    13081 aaaagtaagt gttcattttg agtggttcag caaactgctg acttcttttt tgttcagttc
    13141 acggtaatcc ccaggacgta ggccttgtaa agtcagatct ccgtattttt cacgttttag
    13201 tttttgcaca ggaagaccaa ctgcttgaag catatttttc acttgatgat tacgtccttc
    13261 gtggatcgtc aattccacga tactgtggtt tgtcttagga tccactgata aaatttggaa
    13321 tttagctgga gatgtttttc gtccttcgat ctttattcct tttgtcaaag gtgcaagcat
    13381 cgattttgta gcgatccctt ttacctttgc aacgtaaact ttatccactt catgttttgg
    13441 atgtgtcagg cgctgagcaa aatctccatc atttgtcagt agcaagatcc ccgaagtatc
    13501 gtaatccagt cgacctacag gatagatacg ttcttttacc atcggcaaaa gatccgtaac
    13561 aacttttctt cctttgtcat ctgcaacagc agaaataact cctttaggtt tgtacaataa
    13621 atagtaaccg tattcttctt gataaattgg gacttcatcc acttccacag tgtcatgttt
    13681 cccaactttt atccctaatt cccttacaac ttgtccgttt acttttacac gtcctgcaag
    13741 gatgaattct tctgcttttc gacgagaagt gatgccagcg tgggcaatta ctttctgcaa
    13801 tctctccatt acaattattc tcctttattc attccatcaa agaatagatc tggtgacacg
    13861 tcttcttcaa gtgaaatttc catttcttgt gtatcaggca gttcttctaa tgatttcaaa
    13921 ccaaaataat ctaagaagta gccagttgtt ccatataata tcggccgacc tggtccttct
    13981 actctacctt tttcttcaat cagtttatgg gcagctagac gctgtaccgc tcctgaaacc
    14041 tgaactcctc gaatctgctc gatttcagct cttgtgattg gctgtttata agcgatgatt
    14101 gctaaggttt cgacggcggc ttgagataat gtgtttgatg tcccttgcgc atatcgctta
    14161 agtaagggag ccagctcttt tttagtcgtt aatacataat ggctttccgt ttcaaaaata
    14221 tgcaaagctg agtgcgagtt ttgagtgtaa gattctttta attctttcac taaacttgtg
    14281 acttctgctt cgctgagatt taacagtccg cttaattctt cattactgat cccttcctcg
    14341 ccaacaataa aaagaagggc ttcaagttca cttaatttcg tcatgttcgg tatctcctac
    14401 tgctggataa agcataattg attcatagtt ttctttttgt tgcgcaatga tctgcccttt
    14461 tttcatcaat tctagcaaag ccataaaagt agtgacaact tcacctttag aaggtgactc
    14521 aaaaaaagaa tcgaaagtac agccatgcgc atttcttttt atacgctctt cgataaatac
    14581 cattcgttct tcgatcgttg tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa
    14641 tttcttacgt tctaagattt tctgcatggc acggatcaaa tcgatttttt tgacttgtcc
    14701 tcgcttcaac ggcttttcag catccgctaa cccatcgatg ttcataggtt cttttgtgta
    14761 ataaagactt cgttcctctg ctttttctgt cagtctttca gctgcatatt tatatttacg
    14821 gtattctaaa agctgagtga ccaattcttc tcgaggatct tcttcccata attcttcatc
    14881 gtctgtgccg aattcttgga caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc
    14941 agccatcact aagtattctc ctgcaacagc tagctcgagt gttttcattg tatggatata
    15001 attcatatat tgctccgtga tcgtagcgat cggtatatca tatatatcga tttccatttg
    15061 ctgaatcaga tgaagcagca gatcgagagg accctcgaat acatctaatt taatattgat
    15121 ctccgtcaac tcattcactc tttcttcttt ttctttgcta gccattttcc aatgtaaggc
    15181 tctgtgattt cagttgcacg gatggagaca tccgggtact tttcctgtaa ttcatctaac
    15241 atttgaaagc ccatattctc accgcgataa gacggattca aagaaatgtc atggatgatc
    15301 agctgatcgt tcgttgccca gtaaatacca ataatccctt gaatgttggt tgaaccttct
    15361 ggcgtaaaga aaaaaagttc ataatcgtct tcagattcgt acgtatcaat ctccttcaac
    15421 aaagaagttt tacctgtcag tttcttatgg aaactcaata gtcccatagc aattttacgg
    15481 ttttctttcc ggtaatgtgt taacatcttc tcaccttcct atgactaagc ccttggaaaa
    15541 tgctgcttat aaacatccgt cattcttttc ttcgtgatat gtgtataaat ctgagtcgta
    15601 gagatatccg cgtgacctaa caattcctgt actgtccgca aatcagctcc attttctagc
    15661 agatgtgtgg caaagctatg ccgcagcgta tgtggtgtta cttctttgta aatcccagcc
    15721 tctcgtacta actgcttcag atttttccag attccttgcc gagaaagacc tttcccatga
    15781 ttattgacaa atacatgcat ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct
    15841 aagtagcgtt ccagccattg gatcgcataa tcacctaaag gaatgatccg ctctttatct
    15901 ccttttccaa ctgtctgtac cagtccaaga gaaagatgaa gatctcccaa tttcaatcca
    15961 atcaattcac tgacgcgcat cccagtagca tacatgactt ccaagattgc acgatctctt
    16021 atccctaacg tttttgtcgt atcaggtgct tcaatcagct tttctacttc tgtcagagtc
    16081 aatgtacttg gtaatttctg tgctttcttc ggcgtatcga tatgttgcat cggatcatga
    16141 tcagtgatac gctcttgccg taaaaactga tggaatcttc tgagacttga gatcatccga
    16201 gtaacagttg ctgtcgcttt tttttcttca tgcaacttct ccagaaaacg gatgactaaa
    16261 aagcgatcga catcctgcca tgaagcaatt ttctgctcct gtagaaaatg caagtactgt
    16321 tccaaatcac gttcatagct ttgtcgtgta ttggcggaca atccccgttc aatattcaag
    16381 tagtggagat aatcgttgat ttgctctttc ataataatcc ccctcatgcc tctctatcat
    16441 atcagatacc gcttcattct gatagtcttt ttccataatc tgagcaaaga aaaagccgtc
    16501 tagacactca gacggactgg tttctt
//
LOCUS       DAFEIE010000056        16509 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFEIE010000056
VERSION     DAFEIE010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.058"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            184..1182
                     /locus_tag="LP345_002072"
     CDS             184..1182
                     /locus_tag="LP345_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1760846.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1294..1803
                     /locus_tag="LP345_002073"
     CDS             1294..1803
                     /locus_tag="LP345_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBL1760847.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="LP345_002074"
     CDS             complement(1833..2492)
                     /locus_tag="LP345_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBL1760848.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="LP345_002075"
     CDS             complement(2494..3258)
                     /locus_tag="LP345_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBL1760849.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="LP345_002076"
     CDS             complement(3266..3943)
                     /locus_tag="LP345_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBL1760850.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="LP345_002077"
     CDS             complement(3980..5365)
                     /locus_tag="LP345_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL1760851.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="LP345_002078"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LP345_002078"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="LP345_002079"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="LP345_002079"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBL1760852.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="LP345_002080"
     CDS             6304..7161
                     /locus_tag="LP345_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760853.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="LP345_002081"
     CDS             complement(7242..7577)
                     /locus_tag="LP345_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760854.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="LP345_002082"
     CDS             complement(7644..9014)
                     /locus_tag="LP345_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBL1760855.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9628)
                     /locus_tag="LP345_002083"
     CDS             complement(9092..9628)
                     /locus_tag="LP345_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1760856.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9937..11418
                     /locus_tag="LP345_002084"
     CDS             9937..11418
                     /locus_tag="LP345_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1760857.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11521..12228)
                     /locus_tag="LP345_002085"
     CDS             complement(11521..12228)
                     /locus_tag="LP345_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBL1760858.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12307..12645)
                     /locus_tag="LP345_002086"
     CDS             complement(12307..12645)
                     /locus_tag="LP345_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBL1760859.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12756..13718)
                     /locus_tag="LP345_002087"
     CDS             complement(12756..13718)
                     /locus_tag="LP345_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBL1760860.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLVSGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13733..15064)
                     /locus_tag="LP345_002088"
     CDS             complement(13733..15064)
                     /locus_tag="LP345_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1760861.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15072..15752)
                     /locus_tag="LP345_002089"
     CDS             complement(15072..15752)
                     /locus_tag="LP345_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL1760862.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15971..16450)
                     /locus_tag="LP345_002090"
     CDS             complement(15971..16450)
                     /locus_tag="LP345_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBL1760863.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
BASE COUNT         4885 a         3441 c         2736 g         5447 t
ORIGIN      
        1 tttgcatact tcataataat aataacataa tacctaacct ctcgtaaaaa tactagattt
       61 gttttctttt atttttcatc actagataca ttctataact taccgtttcg atttcgaatt
      121 caaacatttt tgagaagcat tctcaattaa attctgctat agtgtgaaaa gggaggaatt
      181 tttatggaaa tctatgacat tacaatcatc ggtgcaggtc ctgtagggat gtttgccgct
      241 ttttacgcag gaatgcgcca agctaaaaca aaaatcattg acagtctacc tcaacttggt
      301 ggtcaattag caactttgta tcccgaaaaa tatatttacg atattcctgg gtatccagca
      361 ataaaagcaa gtgaattaat cgatcaatta gaaaaacaat taactacttt taaccataca
      421 ttccatttaa aagaagaagt tctctcgctt actcgtgaag acgaagttat cgagattact
      481 acaaataaag gcatccatta ttccaaagca gtcattttag ctttaggaaa tggttcattc
      541 cagccaagaa aattgaattt agataatgct gaatcatttg aaaaccacgg attggattat
      601 ttcgtgaatg atttgatgaa gtatgctgga aaaaaagtcg ctattgctgg aggtggtgat
      661 tctgctatcg attggacgtt gatgttagag cctattgcaa gcgaagttta cttgattcat
      721 cgtcgcccgg aatttcgtgc gcacgaacat agtgtatcac gcttgaaatc ttcatctgtc
      781 aacttgctta ctccctatct catcgatgga ttatcaggca ataatgggga actgacagat
      841 atccggttaa aaaaagtgaa aagtgacgag acgattgatt tgatgattga ttctctgatc
      901 gtcaattatg gattctcttc taatttagaa catctttctt cttggggact tgatagtacc
      961 agaaatgcca ttactgtaaa atcagatatg tctacttcta ttccaggcgt ttatgcagct
     1021 ggtgacatct gtacctatga aggaaaagtg aaactgattg ctactgggct cggtgaagca
     1081 cctactgcag tgaacaacgc tttacactat attaatccaa aggaacgaac tcagcctggt
     1141 cacagcacaa gcttatacga taaaaatctt cgtcctagtt gattttttat atctctttgc
     1201 atttcaagtt aaacccgaaa gcagtttctt gcattttttt catgttccgt taacatgaaa
     1261 tagagaaaga aaaaataaag ggggagcaat aatatggtcg tcaaaactga gactttagaa
     1321 gaaaaggcaa gagaactatt gaaggaacgt ggcgtaactg tagaagatat cgcacaactt
     1381 gtcatgtttt tacaaaaaga ctatatttct gatttgactt tggcggattg tactgaaagt
     1441 gtcaacagcg tgctaacaaa gcgtgaagta cataacgcca ttatcactgg aatccaatta
     1501 gatatattag cagaaaagaa aaaattgatg agtccgttgc aacatattat cgaagatgac
     1561 gaaggccttt acggtatcga tgagatccta gccttgtcaa tcgtgaatgt ttacggtacg
     1621 atcggcttta cgaattatgg ttatatcgac aaggtgaaac ctggtatttt aaaagaacta
     1681 aacagccacg atggcgttca tgtccatacc ttcttagatg atatcgtcgg agcgatcgcc
     1741 gctgctgctg ccagtcgatt agcacacaaa gaaccagaaa aaagaagtcg ccttactcaa
     1801 taattcaaca aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgctttag gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat ggttaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcactatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgattt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaaatcttt caataagtag acaatgctta aaacatcatc ggaactgcat tcagctaagt
     9421 agttttcaaa ataaacagtg atttcttcta atatcttctc ttttaacccg ctgattgatt
     9481 tgaaatgtgt ataaatcggg tatgtagaac aaccgcagaa ctctgctaac tctcttgcag
     9541 taattgactt cattccatat tcttccacgt ataccatact tttgaacagc aaatattctt
     9601 tactataatt tgttactctc cccatcattc ttacctccgt ctcttttcat ctacccataa
     9661 ataaataaca taaataattc taaaaatatt attgataatt atcaaaacat atttagttat
     9721 atccattaaa aatcaatttt tccgccttaa aaacaagaat atcttgacaa aataccctag
     9781 gaaataaaca atagaataaa caaggtaaca aaaaaattaa ataacgttat ataaaaaaga
     9841 aggcgacact ctgtgagaat aacacagact gaaatgactt tccactcaca gtttttgtct
     9901 aactatatac aaaaacagaa taaaaaggag gtatttatgc taattgaagc aagaaaaaaa
     9961 gagttacttg ttctacaaat ggtcattcaa aaaaataatt gttctttaca agaattatcc
    10021 aatgacttac atattccaaa acggacaatc aaagaactga tccgaaaaat aaatgtatca
    10081 ctcaagcaat ttttattgat tgatgaattt atttattcta atcataaagg agagatccaa
    10141 accaaagaaa ccgatcaaac taaaaagtta gctgtttttt ctaagttaaa attatgctac
    10201 ctaaaagaat ccaatcgttt taactatttg atgttactaa tcaattatcc acaaactgct
    10261 gtaccaaaaa aatatttact tgaacaactt tatatatcgc cctcctatct cgaaaaactg
    10321 acaaaacagc tcaatcattc cttaaaaaaa ttccatttac ggatcctatc tgtaaaaaat
    10381 tgctgtactc ttgaaggaaa tgagttatct atccgtctct atctttactt ttttctttca
    10441 gatacatttg gaggtaacga ttggccattt tcctcacttg aattaaatgc actaaaaatg
    10501 aacagtacag atgagcaaat agaaaaaatt tcaaaacaag aaaaaaatat ctacttgctg
    10561 ttaactttat tcatattacg aaacaaacaa caggcatatt ttccaaaaac ttcttctgaa
    10621 atcactgaat tgatggactt attgcagcat acacatgatt attcagaata ctttacttct
    10681 ttttcagtga gtcgcccttg tgaagagaca gaaacagaga gagcctactt taattatttt
    10741 ttctattgtt tttttccaaa tcaaatctct tttcgacaaa aacaggagat tggtttttta
    10801 ttttccacaa gcaaaaacct tatttgtcga caagtcggtc aattgatgac ttacttaact
    10861 caacagtttc ctctcaacca tttagaaaat aaaataccaa tttattttta ttttcttgtg
    10921 ttggcagttg tttttttcga actgttgggt gaatccagca gtagtttttc tacactttgc
    10981 tttccagaag ccacgtccaa tcattctagt tcttttatac aggaaaagaa attaagagaa
    11041 aaaatcgata caattttttc aaaaaatggg gaaagaaacc aaatcagtca ataccttagt
    11101 caattgatcc aacacttact acaaacagaa acgaaagagc agttactcat ccatttgcag
    11161 ataaccaaac agtttacagg aaattatcat cttcaaagcc atttgcagca gttatttcgc
    11221 aaagatgctg ttaaaattac cgcatattca gaacatgctg atttgatcat tacagatcag
    11281 catgagaaaa tttcagatga aacggagact ttctatctgg atacaacgca caatacagtg
    11341 ttatttggca agttaataaa agcggttcat gaactgtata tgaaaaaagg ttatgagaac
    11401 aaaacaaaga ggatgtgaca aaattcttgt cacatcctct tattccaaat aaatggtatt
    11461 caatcagcta actctcggta ttagctcaga tcaaagcgct gatttcacaa cttctttatt
    11521 ttaatctctt cggttgccgc cgaacaataa gatcaagcgc aacagctgca ggaatgtcga
    11581 aagcgctgct gcaacataag tcagtgctgc tgcaaataat acgtgtcttg ccatcggtac
    11641 ttcttcttcc gtcagtagtc cgccttcact caaaatttgg attgctcgcc gagacgcgtt
    11701 aaattcgact ggtaatgtca ccaattggaa aagtaatgct aaagaaaaag cgaaaatccc
    11761 gatattgatt aacgtagagt tccagctaag caatacacct accataatca aggggaacga
    11821 aatcatcgaa ccaaagttag ctgctggaac aagtgctgca cgaatcttca atgggacata
    11881 acccgaagca tcttgtaccg catgtccgca ttcatgagct gctacaccta tcgcagcaac
    11941 tgaagtagac tgtgcagttg cttgagacaa actcaacatc ttattacctg aattgtagtt
    12001 atctgtgaga tctccggcaa tttgttgaac accgacatta tttatctgtt gactttgtaa
    12061 tatatattgt gctgcttgtg taccagtcac attgtttttg cttctcactt gatcgtattt
    12121 tcggaaagta ctattgacgt acgctgacgc aattccggaa ataactaatc caagaatgac
    12181 caaaagaaat gtcggatcta aaaaaccata cattccataa ccatacattt tcgtttcact
    12241 ccttttcgtt tactttattt tatcattagt agtaggaaaa gaatgtgaaa agaccttgaa
    12301 tattctttaa ttctttttca caaattccga tttcagtttc atcggtccaa atccttctac
    12361 cttgcaatcg atattatgat cgccttctac taaacggatg ttcttgactt ttgttccttg
    12421 tttaatggca cctgacgcac cttttacttt caagtcttta atcactgtca cgctatcgcc
    12481 ctctaacaga cggtttccat ttgcatctaa taccactaat ccgtcttcta tgacagtttc
    12541 ttgttcttct ttgttccatt cgttcccgca ttctgggcaa atcaacaagc ctcgatcttc
    12601 atatgtgtac tctgagccac attctgggca atttggtaat gtcatcttct ttctccttta
    12661 aaatctttag tgagcactat tgtaacggaa aaagaagatc ttgaaaagat acatttgtga
    12721 tttttactac aaaaggcacg ttttcgaacg aagtatcatt ctgtttttct gctcttatac
    12781 gattggcata tatcttggat ctctttatag atttcctcta cttctgctaa atcttttgca
    12841 ttcgcaccac ttactaatgg atggcctcct ccatgatggc gtttagccaa ttcattgatg
    12901 atcggcccct tagaacgtaa acgtacgcgg taataccctg aaggctgctg aacaaaaatc
    12961 ccccaagcca gcacttcgtc aatcactcca ggaagtgaaa cgatcgaagc tgtctctgaa
    13021 tcatcgattc catatttatc aagaatttct tgcggaagga ttattcttcc tgcaccattt
    13081 tcatccacct ggatattttg ataaagataa ccggaaagtt tagcgacttt catcggcatt
    13141 tgttcaatct ctctgttcaa agcacttgca tcaaatggat aatttctcaa tatcgaagca
    13201 atctctaatg tacgggacgt cgtggaggga tacaaaaagc gccctgtatc tccgacgatt
    13261 cctgcataaa gtaaccgtgc agccttaacg ttcatcttta aagattcagg aaacatcaaa
    13321 gcaaattctg caatcatctc actacagcta cttgcttttg tatttaccca cacaagatct
    13381 ccataagggt catcattggg atgatggtcg attttgatca gtttttctgc caactgatat
    13441 ctttgatcac tgattctggg tgaattagct gtatcagtca cgatgactag cgctccttgg
    13501 tagaagacat cttcaacttc ttgcatttct gctaaaaagc gaagcccttc aatcgtttca
    13561 cctacttgac gtatttcttt ttctgggaaa ctttcccgta atagttcggc taatcctact
    13621 tgtgatccta atgcatcagg atcagggcgc aaatgcctgt ggataatgat tttatcgtat
    13681 ttttttattg tatctactat ttcttgctgt actgtcattt cactcctgct ttctaagaac
    13741 gttccattac ttgacaaaca acgattgctt tggaaacgat ggtgttttca ataaacactt
    13801 cgatatccag tttagcggaa cgtctgccga tttccaatac acgtggacga atgtctaatt
    13861 cgctttccaa ttggatcagc cgcaaataat gtaggttcac ttgttcaatc aagatatttc
    13921 gtttttggtt catcaccatt gttttttgtg cgacatcaga aatgatttcg ctaagtacgc
    13981 caaaagaaat ggttccaacg ccattgacca tttgtggtgc tactacgaat ttgaacttag
    14041 ggttttccaa acgatttcct tcacggtcag tatcaatcgt atggatattt ccagatatct
    14101 gatccgaaat cgtatctgca atctgcggtt gtcgctggac aagctgcatc gctttcatta
    14161 catcttgccg ggtaatcaag ccttccaatg tcaagtcatc ggaaacgacc ggcatgactt
    14221 ctagcccatc ccagatcatt tgatggctaa cagaggcaat actcattgtt ttctttacac
    14281 tgattggttc tttcgtcatc acccgatcga tgatctggtt tggcgatttc cctaaaacat
    14341 cttttgccgt aacaatcccc atcaaacgat gatggcggtt gacgactgga aaacgcgaat
    14401 gctgcgtttc ttctgacaaa cgctgataat cagaaatcgt atctgtctgc tgcaaataat
    14461 gagtcttttc agctggcata tagatatcac tgacaagcat gatatctttt ttgatcaatt
    14521 ggtcgcttaa cgctcggttg atcatggttg cgactgtaaa tgtatcataa gaggtgcgta
    14581 agatcggcat ttcaagatca tcagctagct ttgcaatctc agcagtcgta ttgaatcctc
    14641 ctgtgatcaa tactgcggcg ccatcttcca atgctaattt ttggacttcc gcccggttgc
    14701 cgacgatcat tagtgatcct ggcgtaatat agcgttccat ggcatgttta gtcatcgcgc
    14761 cgatgacgaa tttattcaag accttgtcta atcctgccgc cccgcctaaa acgtcccctt
    14821 caatgatcct gacgacctcg ccaaatgtca aacgttcaat atgttttttt aatttgcgtt
    14881 cgatacggat ggtccctact cgttgaattg ttgaaactag tccgacattt tctgcatctt
    14941 tgattgcacg gtacgctgtt ccttcactga cattcaattc ttttgcgatg cttcttacag
    15001 aaattcgatt gccaacaggt aaactttcaa tatattctaa aatcaaatca tgttttgtcg
    15061 ccattttctg cctacacttc cagcgtttcc gagacgctca ttatttttcc ttcactatct
    15121 tccagtaact ctacaaaaga ttcgggatct tgttcaatga cagggaaagt attgtaatgg
    15181 attggaacta ctttcttggc acgaattgtt tgcgcagcct ttgctgcatc ttctggcccc
    15241 atcgtatagt tatcgccaat cggcaagaaa gcgacatcaa tatcgaattc ttctgcaagc
    15301 aatcctagat cactgaaata agcagtatcc cctgcatgat aaatcgtttt tccttctgct
    15361 tgaataataa ttccgctagg ctcgcccata tactgaacga taccgtctac ttcatagctt
    15421 gaactatgct gtgcatgtac gaattttacc acgccgaatg gaaacgcatg ttttccaccg
    15481 atattcatac cgaatgaatc tactcctctg ctgttcgcat aatcagcaat ctcaacaata
    15541 ctgataattg tggcttgatt ttcttttgca ataggaatca tatctcctat gtggtcacta
    15601 tgaccatgag taatcagcaa ccaatctgtc tttacttctt ctgcagttaa gtctgtcaat
    15661 ggatttcctg taataaacgg gtcaatcatc acgcgttggc cattttccat ttcaattgtt
    15721 aaacaggaat gtccatgata cgtaattttc atattttaca cctcgcgttt tctctgtatc
    15781 ttttttatta aaaacgattt catcacttgc acatcaatga aaaaatatag ctgctaaata
    15841 tattttcatt ggattgatag tacagtatgt acaaagcaat tgtaacagat aatacaggat
    15901 gcaccaagta ccaagcagat ataatctcaa gtttgaggtc tctgctctgc ttagcttctc
    15961 ttctcgtccc ttaactaatt aaatcagcgt aaataggatg gacgatcttt tctaaatcgg
    16021 ctacttttat ccgaaggctt ctcccgattt caccgcttga cacaattact tcttcttttt
    16081 cttttaaaga actgtctgct aaaaaacaat aatcaggatg tgcgagtttt attccaatag
    16141 gggtgtttgc tccgtgggga tatcctgtat gcattaatac aaaatccatt ccaggaaaac
    16201 caactttacg atctttcgtc acttgtctcg tttttttgta atctaagtga tcgttcaaag
    16261 gaatcaatgc gatgatcacc ccagttttgt ttcctttcac tacgagagtt ttacatatca
    16321 aagctggatc aatccctctt ttttgtagtt cttctgtgaa agattcttct accacatgac
    16381 taaaatcaag tggttgatag ctgatctttt gttcttctaa ataacgttcg acttttgttt
    16441 gactcatcat tgattcactc cctttattct atcgtttatt ataaagcgag ggatgctgta
    16501 ttcaaaaat
//
LOCUS       DAFEIE010000057        16464 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFEIE010000057
VERSION     DAFEIE010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.059"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..495
                     /gene="scm"
                     /locus_tag="LP345_002091"
     CDS             <1..495
                     /gene="scm"
                     /locus_tag="LP345_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBL1760864.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSK
                     TSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYK
                     KSKR"
     gene            complement(650..1636)
                     /locus_tag="LP345_002092"
     CDS             complement(650..1636)
                     /locus_tag="LP345_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL1760865.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1659..2225)
                     /locus_tag="LP345_002093"
     CDS             complement(1659..2225)
                     /locus_tag="LP345_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBL1760866.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2239..2655)
                     /locus_tag="LP345_002094"
     CDS             complement(2239..2655)
                     /locus_tag="LP345_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL1760867.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3112..5046)
                     /locus_tag="LP345_002095"
     CDS             complement(3112..5046)
                     /locus_tag="LP345_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1760868.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5327..6283
                     /locus_tag="LP345_002096"
     CDS             5327..6283
                     /locus_tag="LP345_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBL1760869.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6373..7476
                     /locus_tag="LP345_002097"
     CDS             6373..7476
                     /locus_tag="LP345_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBL1760870.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7489..8442
                     /gene="menA"
                     /locus_tag="LP345_002098"
     CDS             7489..8442
                     /gene="menA"
                     /locus_tag="LP345_002098"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBL1760871.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9256..10602)
                     /gene="gor"
                     /locus_tag="LP345_002099"
     CDS             complement(9256..10602)
                     /gene="gor"
                     /locus_tag="LP345_002099"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBL1760872.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10736..11989)
                     /locus_tag="LP345_002100"
     CDS             complement(10736..11989)
                     /locus_tag="LP345_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL1760873.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(11995..12918)
                     /locus_tag="LP345_002101"
     CDS             complement(11995..12918)
                     /locus_tag="LP345_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL1760874.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13139..15631)
                     /locus_tag="LP345_002102"
     CDS             complement(13139..15631)
                     /locus_tag="LP345_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBL1760875.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15638..16105)
                     /locus_tag="LP345_002103"
     CDS             complement(15638..16105)
                     /locus_tag="LP345_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBL1760876.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16241..16314)
                     /locus_tag="LP345_002104"
     tRNA            complement(16241..16314)
                     /locus_tag="LP345_002104"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16278..16280),aa:Arg,seq:acg)
     gene            complement(16372..16445)
                     /locus_tag="LP345_002105"
     tRNA            complement(16372..16445)
                     /locus_tag="LP345_002105"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16409..16411),aa:Pro,seq:tgg)
BASE COUNT         4859 a         3450 c         2930 g         5225 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagcacgga cacgtcagct
      181 tcaagtgaca gtacagatac atcctctacc acaagtgata gctcagattc atcaacttca
      241 agcgatagta cagacacgtc gtctaccaca agcgatacac gtcatgcaag tgtctccttc
      301 tcaaaaacaa gttcggataa caggacgaac tttaacttaa ctaataaaac aagcaatgac
      361 aatggaaaca aatcaaaaag agcacttcct aaaactggaa gtcaatcgaa taattggata
      421 acactcgcag gcgttatatt acttgtaatc ggtttaagaa tcacttttat gagttataag
      481 aaatcgaaaa ggtaaaaaaa tattcaagat aaaaaagagc aacgtcgcta acggacgttg
      541 ctctttattt ttgcttttta tcataaatac aagaactaca attcaatttg tcaaaaaaca
      601 cgtagatttc cttctgagaa atttatttac gtatcgaacc tttccctatt cagtctttgc
      661 gatccaaaat cagttgggta agggaaaaga gattctcttt tgttcgaaga gaggtggcag
      721 gtaatttctt tatttccttc aaagcctttt ctgtgtaaga ggccgctaac ttcctagctt
      781 cttccacgcc tcctgtatgt tcaacgattt tgcgtacggc gtcgacatct tcttctgtca
      841 ttgccgcttt cttctctaaa taaggtagta gctttggttt gtttttttgc aaagagtaga
      901 tcaacggtaa agaatagacc ccttgacgca tgtcttctag tacaggtttg ccgatttcct
      961 ggctctcttt tgtataatct aaaatatcat cgataatctg aaaggccatc ccgatagaaa
     1021 gtccgatatc tcctgctttt tttgcgaagc gctcgcttgt tccactttca aaagcgccaa
     1081 cagaacaact taattggaac agttcagctg tcttacctga aatattttcc aaatattctt
     1141 ttacagaaag ttcataatta tagcgatcat ccatctgccc taattcgcca ttcaatactt
     1201 tttccatact gcgagaattc aattggagac ttttcaagga agtggagtaa tcagacaata
     1261 gtttaaaaca gcagacaaat aaatagtctc ctgcatagac agaaacgaca ttaccaaact
     1321 gactacggat attaggctga ccacgtcgca gatccgcttc atcaacgata tcatcatgga
     1381 tcagtgtggc cgtatggagc atttcgatag aagctgccaa agcgatggct ttgtctcgat
     1441 cttgctctgg tccaaattgt gagaacaata gctgataggc aggacgcaac agctttccgc
     1501 cggcatggat cgtttctttg atggcttgtt cgacaggttt gtttttcagg cggacagttt
     1561 cttccatccg ttttagtgtt tctgtcaatt ctttacttaa agcaggatag ttttcccaca
     1621 ttggatgtag cttcataaaa aaactccttg tgtgacgatt attttttggt aaacattggg
     1681 ctccattttt gtttggttcc ctgctcataa tctttttgga atcgttgaag tgtctgcaca
     1741 tgtcgtaaaa gataattcgc tgcgatcccg attgcaatcc ctgataaaat ccctaaaact
     1801 gaaaggactg gcaagtacaa catgactgtc catgattgtg caatgaaaga agccatcaaa
     1861 agctgtccga cattatgcat gaaaccgccg gccgcactaa ttccgatgat actgacacgt
     1921 tttggtccta attgcttgac caataacatt ccaaaataac taagcaaagc accactcata
     1981 ctataaagga atgtggaaat cgttccgcct agcaaagtag tcaggaatag tcgtagccaa
     2041 agtagtaaga agctgtcttg ttttttcatg gtaaaaatgg caacgatcgt gattagattg
     2101 gctaagccta gttttgcacc aggcgcaaaa gaaaaaggat aagggatcat attttccaat
     2161 aaaccaatga tcactccttg tgcaacaagt agcgaaatat aaatcatttt ttgtaattta
     2221 ctcatggtgt gtgaaggtct aataaatcag actgtcttcg tcacctccat ctgttgaacg
     2281 gacttcgatc actaatttat gtggcaaaca gacgatggtt tcgccatttt tcgttgccca
     2341 gcctcgacgt acgcagatct ggtcatcgca atctgcttct tttatccgta ctcgatcgcc
     2401 atctatctcg atcaagttat aatctccgtg ttcatctttg taagtatatg tgttgctctc
     2461 ttctccagcc atcaaaggga atgttttgat ttctgtgcca tccacacgca gtaccgcttc
     2521 tttttctgct gttgcggtgt tttgctgaag accaaaaatc atgactggta aaaaagaaag
     2581 aacagtcaaa agcaaaataa taaaaacatc ccaaggtttg agcagacttt tttcagcaaa
     2641 ttctttaagg ctcatttttg ttctcctttt tccagattaa ctcacccaat tttagcataa
     2701 aaacaagagg ttgtgacacc tgtgtcttgc tttgagtaat aagaacgaag aatagaaaac
     2761 agctttccat gttttctaat tctttgggct tattaccgag aagcagcagg tggaacaccg
     2821 tttataacaa gaggttgtga cagaagtggg caacttcaag aaataagaag gaatttacga
     2881 aaattacttt tcaagttttt gtgaaatttc ggcttatttt tcgaagaagc tacttctgga
     2941 acaccgttta taacaagagg ttgtaacaga ggttgtgaca cctgtgtctt gctcatggag
     3001 gcttatctcg ggcatcttat tcctttaatt ttacataaaa aggaggctgt gacggtttgt
     3061 ctcagcccct ttctattgaa atcttgcatt caaataacgt tctttatcta tttatttctt
     3121 gccgtactgg gaacttggtc taccgtacca ccaattacct agtgtacgtt gtagccatgg
     3181 aattacccag cgatccaacc caatcgcacg tccggaaccg ttcatcaatg cgaaagcaac
     3241 aaaaatgaac caaatgttta cccagtaaaa catgcctgat aagcagaacg tgatcaccaa
     3301 tacaatcgtt gtcgcactgc atagccatgt gaataatcca gcaatcaatg ctaatgccaa
     3361 ggcaatttca aagaatacca tgaatttttg gaagaacatt gctacatcat tgtttggcat
     3421 gatcacttgc atgatctttg tgaaccagtc tggtgacttc tcaatcacag ccattggttc
     3481 ttcaccgtat gcataactca aaccaaaatg tgcagcttga gtcgctgctt ctccggcact
     3541 tgcccctgct ccgctggcag ctgtggttgc atcaccagca gcagaagcac cactggcaac
     3601 atctgttaca ttgtattccc atgtccaagg gaacacactg tttccagtga accatgatcc
     3661 ttcaccaaac caagtacttg gtttgaacac ttcaccattc ccaatgattt ttttggaagc
     3721 ttcaacgaac caaactaaac catagaaaat acgaagtggc acactccata agacattgcc
     3781 gtaacgagaa gaatgtcctc gagtcacgtt gcgatcatct ttgatatgga aaaactcatg
     3841 cattaaatat tggaacatat aataaccaga acgaatatca aagaagtatt tcaaattcac
     3901 gatatgtttc attacgatag ctaaaaatcc gcttaaatgg atcttatcaa ataggttagc
     3961 taccccccat ttggcaccaa tagaaaccat aaatccttga tagtttcctt taaatttatg
     4021 cttttctccg cctttgatcg aagccacgat attcgctgcg gctgtgtgtc ctgtttgttc
     4081 agcagcttga acgatctgcg gtgtcggtgt tcctgggaat tcttcataaa agactaaatc
     4141 accaatgata tagatgtttt tatcttcgta gccttttgcc tgcatatatt cattggcgat
     4201 caaccgctgt ccgcgtgctg attctaatcc aaagtcagca gcgtcagaag ttcctttgac
     4261 accagctgtc caaatcagtg tgtgagtcgg aatgttgcgt ccgtctttca atttgatatg
     4321 atcagcagcc acttctacga ttggtgcatt caataataat tccacgttgt gcttacgcaa
     4381 atagcgttca gcttttgcag catcatttcg atccaacata ttcaagatcg tcggcattgc
     4441 ctctacgacc atcagtgtga tttcgtttgg atctaattta taatctttgg ctaggcgatt
     4501 tttccagtcg atcagttccc caatcatttc aataccggta aatccagaac cacagacaac
     4561 gaaagtcagc atggctttac gcagttcatc atctggttcc aatgcagctt ttgctactgt
     4621 cttctcaata tgttcccgaa tccttacaga atcttcaaat gaccaaaggg tgaatccgtg
     4681 tgctttgaca ccaggtgtac caaagtcatt cggctctccg cccattccaa ggatcagctg
     4741 atcaaaagga taggaaccta atttggtctt gacgattttt cgttctttat cgataccgat
     4801 tacagtgtct gtgacaagtt gtacattctt ttgacgagca aacaaatgct gcagatcgta
     4861 ttggattgct tctggttcta cacgtccgcc agctacttca tgcaactcgg tcatcatagt
     4921 atggtacgaa tgacgatcga tcagagtaat tgctacatct tcttttttca gtttctttgc
     4981 caagtatttt gtagctgaaa caccggcata tcctgctcct acaacgacaa tattttgctt
     5041 tgccattgat catccgctcc ttatagacta tctatataat gaatatatga taattctttt
     5101 agtttgatac ttattacaca atctccatat attatataga tgttctgttc ttttgtctaa
     5161 ctccttttgg atttttttca aattttaaaa taaagcgttt tttcacgaaa tttgctgaaa
     5221 gaaaacgttt gaaatattac atgggttatt tatcaaaaat agttgactta taggctaaaa
     5281 agattagaat gtataatgaa tcacaaagaa aaattgtgga ctagaaatgg aatggtgggg
     5341 tattaaaatg aagaaaaaac gttttgtaac tggatttgcc gtattagcat tttcagctct
     5401 agtgttaggc gcttgcggcg cagatgacaa cggaagctca aactcttctt ctgaatcatc
     5461 tacagcacaa tcttcgactg caaaaagcac aacagaatca tctgcaaaag ttgtagctgg
     5521 cggagatttg caagacggca catataaatt agaagaaaaa aattattcaa atggttaccg
     5581 tgcagtcttt gaaatggttg taaaagacgg caaaatcact gaatcaaaat atgataacgt
     5641 caatgaaaac ggcgaatcaa aaacaaaaga tgcagaatac aacaaaaaca tggaagcaaa
     5701 atctggcaca aacccagaaa aatacattcc tgagttgaat gaccaattct taaaagcaca
     5761 aagcgcaagc ggtgtggaag tcgtaactgg agctactcac tcatctgaaa gcttccaaaa
     5821 ctacgcacaa caattgatcc aagctgctca agctggtaac acagatacaa tcgaaatcga
     5881 caatggtgct gatttgaaag acggcactta caagcttgaa gaaaagaact actctaacgg
     5941 ctaccgtgtg caattcgaaa tgacagttgc tggcggcaaa gtaactgaat caaactttga
     6001 ttatatcgac aaagacggta aatcaaaaca agatgataca gaatataatg aaaatatgaa
     6061 agcaaaaagc ggtacagaac caaaaactta catccctact ctgaacgacg aattcgtcaa
     6121 agcaatgggc gaagaagatg gctcacctgc taatgtagaa gttgttacag gtgctacaca
     6181 cagctcacat tcattcatca tgtacgcaca acaattagtg aatgcagctg aaaaaggcga
     6241 cactcaaaca atcgaagtag ataatatcgt aacagaaaaa taatcacata atcatactaa
     6301 taaaagttgg agggtgggac gatagccaga ttaggcagtc gtctcacctt tcaaaatgaa
     6361 gagaggaaaa agatgcggaa aaaactacta ttttccttaa tcacactggg catctctttt
     6421 atggtgctaa ctggctgcag caactcagca aataaaacaa ccactgaaag ttcagcagct
     6481 accaagatat tgaaagatcc atattctgat gaacagttct tgttagggac ttacgttcgt
     6541 atccgtgtgt atgatgaagg caaagaatca gcattgaaac ctgccttcga tcgagtaaaa
     6601 gaacttggtg ataaaatcac gatcaatcaa aaaggttctg agatcgatga agtgaatgag
     6661 caagctggga tcaaaccagt aaaagtttct gatgacgtct acacgttagt caagcgggcc
     6721 tacgaatata gccaagattc tcaaggcgga ttcgatatgg cgattggtgc aatcacacaa
     6781 ttatggcgaa tcggttttga tgacgccaga aaaccttccc aagaagaaat cgatcaggca
     6841 ttgaaattag tggattatca taagatcgaa ctaaatgaca aagaaaaaac tgtttatcta
     6901 aaagaaaaag gaatgatcat cgatttaggt gcaatcgcca aaggttacat tacggacgaa
     6961 gtagtgaaag tcttgaaaaa acaaggagtg accactgcca tcgttgactt gggcggtaat
     7021 gtctatgtct taggccacag cccaagaggc gaaaaccaag actggacagt cggcatccaa
     7081 gatccgaaca tggctcgcgg atctgtttta ggttctatta aagaacggaa caaaacatta
     7141 gttacctctg gaatttacga gcgttattta gaagtagatg gcaaaaaata ccatcatttg
     7201 tttgatccaa aaacgggtta tccgttcgac aatgatatcg caagtgtcac gatcataaca
     7261 gataaatcaa ttgatggtga cgggttgtct acagcagtct tttcaatggg tgtgaaaaaa
     7321 ggactggaat acgtcgaaag cgaattgaat aacgggacgg aagcgatctt cgtgacaaaa
     7381 gacgataaag tatatgtgac cgatccaatc aaagacacct tcaaattatc ggaggactcc
     7441 cattacacga tgggtgaccg ttctgaacta aaataaggag tacgaaccat gacactaaaa
     7501 atctttttag aagtagttga aatacgaaca aaggtggcta gtgtatttcc ttttgcggta
     7561 ggggtattat tctctatcgc tttttttcat gagatacatt ggctaaacac ttttttattt
     7621 tttattggaa tgctagtttt tgatttagcg actaccgcta tcaataatta catggattat
     7681 gaaaaggctc attctgaagt atataagtat gaagaaaatg tcattggccg cagaaatcta
     7741 tctcctgtat tgattcgaaa catgatttta gctatgattg catttgtttt tgttatcggc
     7801 gttattctaa cgatcaatac gggttggctt ttacttttga tgggatttat ctgttgtttt
     7861 attggagtat tctatacatt cggaccgatt cctttatctc gaatgccttt aggggaaatt
     7921 ttcagtgggg tgactatggg ccttggaatt tttgccatgg tcgtttatgt caatacattc
     7981 ggttcagatg tctatgatct gacagtcaac ttttcatctg gacaatttga tttggtagga
     8041 aatctttggg ctatagcagc aatcgtatta gcttccttac ccttggtgtt tacgattgcc
     8101 aatatcatgt tggctaataa tttgcgggat cttgaccgtg atattgaaaa tcatcgctat
     8161 acactagttt tttatatcgg acgtcctgcg ggaacagtct tattccagct attgatgtat
     8221 gcttgctatt tcgtgatttt aatggggttg ttgagcggta tctatgaatg gccgatcttg
     8281 gtcaccttct tgaccttgcc aattgtgaag aagcatttgg atcaattcaa gcaaacgtta
     8341 ccccagccta tcagtttcag ctattccatc aaaaatatgg tcttattcaa tgccagttat
     8401 gtattggggc tattactaac aatcattatg caagccattt aacagcatga agaggttgtg
     8461 aaaaaactgc cctgcatcaa gtaataagaa cagccaaata aaaatagctc cttatatttt
     8521 tcgtttggtt gggcttatta ccgcagatgc aagcttttga acaccgttta tcaggaggtt
     8581 gtgaaaaagt cgcttagttt cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat
     8641 ttttgcataa atttggctta ataccgagaa actggctttt gaacaccgtt tatcagaggt
     8701 tgtaaaatca gtgttttgtc ctgagtatta gagaaacaaa tggaaaaata gttcctcata
     8761 ttttgccgtt ttttgagcta ataccgaagg acagctgatt gaacactatt tgttcggaaa
     8821 aagtgactaa ctatgacaca atttttttca cagtcccttt tttcacttga tttgattcgt
     8881 accagcgaac ttgacgagaa ctttcttggt ttggtaacta tatggtattc ttttaacatc
     8941 ctcgtttgct tcttctaatt tatttataca aagtcacact tttttaaaca tctgttcttc
     9001 gatacatttc tatttctttt aaacatcgat accaatattt tgaacttaag agtgcatacc
     9061 aaatggattc atttactctt cgtcagttac gaagataatc aaaatctcca acttccctac
     9121 ttatttcgtt ttgagaatta tcgaagcaat cttacataaa taactaaaaa acaaaaaacc
     9181 agaaaatcag tatactgatt ttctggtttt acatggtttg ttcaataaaa agctgttgga
     9241 actgttaata ttaaattatc gcatcgttac gaattcttcc gctcctgttg gatggatggc
     9301 tactgtattg tcaaagtctt ctttagttgc acccatcttg atagccacgg caaaaccttg
     9361 cagcatctca tcgacaccaa caccaatagc atgtaagccg acgattcttt cttcttttcc
     9421 gacacagatc aatttcattt cgcatttttg gcgataatca tttaatgcaa agtacattgg
     9481 ggtaaagcgt gaacgataaa ctttcaattc attttcgcca tatttttcca atgcttcttc
     9541 ttctgtcaaa ccaattgttg caattggtgg atgcgtaaag acgactgtcg gaacaagttt
     9601 atagtcaaga taagaatctt tctttccatt aaataaacgt tctgataaac gtctaccagc
     9661 tgcgattgca acaggagtca gatctaattt accgatcaca tcaccaacag caaaaatatg
     9721 ttcatccgtt gtattttggt atttatctac tttgataaac ccttttttgt ccaattccac
     9781 atttgtattt tccagaccta atttttcggt attcggtaca cgtccaccgg caaaaagtac
     9841 acaatcacca gttaaggttt caccattttc aaatagcacc gtatattcgt cattgttttt
     9901 agtaatttct ttagcaatat gatgtgcgta agtttttatt ccagcttctt ggtacatttg
     9961 gatcaaattg tccgaaagca ttttatcaaa cgttctaagt ggtcgttctt ttcgatatgc
    10021 ccacatgact tcactaccta aaccacgaaa tacacctgaa agttcagccg caatgtatcc
    10081 agcacctaaa acgattgctc tcttaggtaa ctctgttaat tcaaaaaatc catttgaatc
    10141 aattgcgtat tctccaccag gaatggtcat tttacttgca cggcctccag tagcgatcaa
    10201 gattttagga gcacgatagg tttcaccgtt tacttcgatc gtttgactat cgataaaagt
    10261 agcgtaacct tttatagcct cgacatgatt gctatctaat cctctttgat aagcaccgtg
    10321 tagaaaatca atatattttt ctcgtctttc tactagaccg gcgaaatcaa cattttttaa
    10381 atctgcttgg ataccgtaac ttgaggcatc tcgttcaatt gtttccaaaa tcgtacttgc
    10441 ttgccacata acttttttag gtacacaacc gacgttgaca catgttccgc ccaattcatt
    10501 cgcttcaatc agcaaaactt ttgcgccatg catccctgct ctgtttgctg aagcaatacc
    10561 gccagagccg ccaccaatta cgatgtaatc atatatttgc attttgttcc tccttattga
    10621 agagatcaat caaaaccttt atttaacgat cctttttcta cagaaaacaa gtgtaacact
    10681 tttcttgaat tttgtatgcg aagatgctta aaacagggat atatcagctt tttccttatt
    10741 tacgttttcg gatcatatct ccaggtttca ccggctgtgc gactggcata gttaaaatca
    10801 tcattggatt tggtgctcgg tcaatggatt cgccttcttc attatgcata acttcaacgg
    10861 tttgactgaa atgactgaat cctggaccat aaaattcgat ttcatctcct acagaaaaca
    10921 agtttctctg acgtatcgta gcaatctgtg ttgcctcatc ataagataat acttcaccga
    10981 caaatttata tactgggatt ttacgacgtt caccgaataa ttgttcgttt tcagttggtg
    11041 tattgtagta aaaacctgta gctaattctc gttgtgctac tttccataac tcgtcgatcc
    11101 attcttgctt gcagacatag ttttcaggat cttccatata actgtctaca gccgctttat
    11161 agacatttga caccgtagat acataatgga tcgatttcat tcttccttcg atcttgaagc
    11221 tgtctacgcc gttttcaatc aattctggaa tatgttcgat cattgacata tccactgcac
    11281 tcatcgagaa ttcttcttcc acttcgcctg tatcagttaa actgtttcgt tcttgaccaa
    11341 aaggcatatc gaacaatcca tacttccagc gacaagattg agaacatccg ccacggtttg
    11401 catcccgcat cgacatatgg ttggacaatg tgcatcgacc agaataagag atacacatgg
    11461 caccatggat aaatgcttcg atttcggtat ccgtattttt acgaatctct gccacttcct
    11521 ccattgaaac ttcacgagct aaaacgacac gttccaaccc ttcttctttc cagaattcca
    11581 atgtctcaaa attagttgct gaagcttgag tggataaatg gatcggcaga cctggggctt
    11641 ctgtcgcaca aatttcgatc aaagctggat cagaaacaat cactgcagaa ataccgacat
    11701 cacgcaaact gcggaaaaat tcccctgctc catcttcatt tccttcatgg gtgaccatat
    11761 tagcagcaac gtataccttc gcatcatgtt cttttgcaaa agcaactcct tcagccattt
    11821 cttcataagt aaaattacct gcacggcttc ttaaaccata tgcattcccg ccaatatata
    11881 ctgcatctgc tccataatgg atcgcggttt ttaacttttc cagtgttcct gctggcgcta
    11941 ggatttctgg tcgtttcaat tttcttttta ctgtcatttc tttcatcata ctccttattt
    12001 gatagcagaa ggatcaatat aaaagaatcc tgtatctaat tcacggtttt caggatgcaa
    12061 tttactgatt tcgctagtca ttttttccgc tttttcttga tcccagctac cttctaaaat
    12121 ttgttttttt gcttcggcga atagtcgagt gatgtttacg aatttttcgc ctggagtaaa
    12181 taatccgtcc aatttccatg tacagtaatg atgctgataa agttcattca attcattcga
    12241 gagattcaga tcattgctgg caaaaatatg tgtgccatga ctatcttcat aaatagaata
    12301 atgtgtctct tcttttttag gttccgagat aaaaagacct ctttcacgat ctttttgttc
    12361 gtcttgtttc gtatagttat agtaattctg tagcagtgga cgtttggatt gatggatgca
    12421 tgtagcacca tacacaaggg tttctacagg aatatcgagt ttttcttcca tcgccttcat
    12481 ctcttcaaaa ggaacttcac gagcaagtac tgctccaact gcgccttttt tcgcccagaa
    12541 attgatttga cgtgcgctcg ttactaatgt ttcagcatca taaatatacg gtatacgcaa
    12601 ttcaggattt tttttcatcg tataaataat acctgtatca ccaactgtga tcacatctac
    12661 gtttatttct tttaaaaaag ccaaatattc aggtacattt ttcatttttt caggatgaat
    12721 gatcccattt acagcaatat tcgctttttt accatacttg tgtgctaatt ctaccaattg
    12781 tcgctgttct tctcgtgtaa atgaagcagg cagacgcaat ccaaattgct cttcaccgaa
    12841 atatagtgta tctgcacctg cagcaagcaa ctgttctgct tgttcaatag tttctactgt
    12901 ggttatgagt tcgatcataa ttttctcctc ctacaacttc ataatagtag catagctcta
    12961 aaaactttcc aatacttctt ctatttaaag tcggattttt gaaaattatt tcacaaaaaa
    13021 tcaaaataaa gttcgatata ttctgtccaa atataaaaag agattgtgac aaaaatcttg
    13081 tcacaacctc ttaatcaagt cttactatta taaaaattca gctacacagg ccaagtaact
    13141 atagggaacc tactgtttcc tttttaggtc cgcgaacatt caatgtgatc ttaccttttg
    13201 aagcacctac tgttacgtgg tcacctaaac gaatttctcc gccaagcaaa gcctcgctca
    13261 atcgatcttc aatttctttt tgaagtgcgc gacggattgg acgtgcacca tattcaggat
    13321 caaatccagc tttcccgatc acatcgattg cagatggtgt gattttcact tgaatatctt
    13381 gttctttcaa tcgtttgata atcgctttgc tcatgatttg gacgattgta tggatttcat
    13441 ctttactcaa tgaatggaag acgacagtct catcgattcg attcaagaat tcaggtcgga
    13501 aagctttctt taactcttct aagatacgtt tttgcatggc tttgtgatct ttagtaacat
    13561 cttggacatt gaatccgaca tttttttctt ctcgaatttg tgtcgctccg atatttgaag
    13621 tcataatcat gattgtattt ctaaagtcca cttttctacc tttagaatct gttaaatgac
    13681 catcatccaa tacttgcaga agtaaattga aaacgtctgg atgtgctttc tccacttcat
    13741 ctaagagaat cactgaatat ggtttttgac gaattttttc tgtcaactgt ccaccttcat
    13801 cataccctac gtatcctgga ggagacccga ttaatcggct tgtactgtat ttttccataa
    13861 attctgacat atcaacacgg atcagggcat cttcacttcc aaacatgact tctgaaagtg
    13921 ctttggccaa ttctgttttt ccgacaccag ttggtccaag gaacatgaat gaaccaattg
    13981 gacgatcagg atctttcaat ccgcttcgtg cacggcggat cgcacgtgaa actgctttga
    14041 cagcctcatc ttgaccaacg acacgttcat gcagaagtcc ttccagttct aacaagcgtt
    14101 cgctttcttt tttctccaac tgctgtagag ggacaccagt ccactccgat acaactgtag
    14161 caacatcttc ttctgttaca cgatcagaat aaccttgctc ctgttttgct tcaattgcag
    14221 aaactttttg cagcttttta cgtagtgctt tttcttgtct gcgtaattga gcagcatttt
    14281 caaagtcttg tttttggatc gctgcttcct tttcttgtac tagttcatcg atttctagtt
    14341 tgatcacagt tgattttgtt aagtgatcgg tttgatccaa acggactttc gctgctgatt
    14401 catcgatcaa atcaattgct ttatcgggta gttgacgaga agtgatataa cgaacagaaa
    14461 gattgactgc tgctcgtaca gcttcatctg tgatctccac tccatggtgc tcttcatatc
    14521 ttgtacgtaa tccttgaaga atcacttctg cttcttcagg agttggctca tctacttgaa
    14581 tgcgagcaaa acgtcgctct aatgcagaat ctttttcgat atatttttga tattcatcta
    14641 gggtcgttgc tccgatcgtt tgtaattctc ctcgagctaa cgccggtttc aagatattcg
    14701 aagcatcaat tgctccttct gctccacctg caccaattaa ggtatgcaat tcatcaatga
    14761 ataagattac ttgaccatca ttatagattt cgtcgatgac ctttttcatt cgatcttcaa
    14821 attcaccgcg atatttcgta ccagcaacca aagatcccat atcaagcatc atcaggcgct
    14881 tttcttgcat gtcttctggc acttcaccta aaatgatttt ttgagctaac ccttcagcaa
    14941 tggctgtttt gcctacacca ggttcaccca ccagtacagg gttattcttt gtccgtcggc
    15001 taagaatctg gataagccgt ttcacttctc tcgaacgacc aacaactggg tccagcttgt
    15061 tttcttttgc taatttcgtc aaatcacgtg ctaatgaatc tagcgtaggt gttccttgcg
    15121 gtgtttgccg tttatcttgt acatttacat ttctacgacg attcattcct tttccagcag
    15181 aatcaccagc tagccccatt ttttgtttca gaacttgacg ggcttttgaa aggctgatac
    15241 ctaagttgat catgattcga gtagccatga tactttcatc ttttaataag ctcatcaaaa
    15301 tatgttctgt tccaactttt tgagaaccag ttttcttcac ttcgctgcta gctaaagcaa
    15361 aaacttgttt cattcttggt gaatatggaa gaaagactcc tttagggtaa gaacggatac
    15421 caccataacc aatcagatgt tcaatttctt cataaatttc cgtttcattc aaatccattt
    15481 cacgtaatac ttttccagca attccatttt gctcgaccac taaggctagt aaaacatgtt
    15541 ctgaactaac tgattgatgt ttcaaccgtt ttgcttcttc ttgtgcaatt tctaatactg
    15601 cttgggctct ttcagtaaaa agttcttcca tctaatctca cttcccatct tcataactta
    15661 aacgttccag aaatgctcgg agaatccgag cacgtgtatg atcttcatat tcattgaaat
    15721 tcaatgtgtt ttttgcaatt gcactcaaca tcaagtttcc ttcttttttt gtaattattt
    15781 ggtcttcata aagtttttga ataatagcaa aagcattttt ctcactgatt gtatcatcaa
    15841 ataactgatt tatctgctca agtaattgtt ttttatctga aatccttact tttgcaattc
    15901 gtatataacc accaccacca cgtttgcttt ctactagata accacgttgg atggtaaaac
    15961 gggtattaat cacatagttg atttgtgaag gaacacagtt aaagaggtct gccatttcaa
    16021 tccttcgaat ctcgatcatt tcactatttt ccagaatttt ctttatatat gattcaatta
    16081 aatccgaggt attctgatgt gccatcttat tcattccctt tgactaatat tgaccttaat
    16141 tataacgaat ttgataatag aaagaaagaa gaacgctttt tgttaaataa atcctttaga
    16201 atcaacaaaa aaaaatacgg aatatactat tccgtatcga cgcgcccaag aggagtcgaa
    16261 cccctaacct tttgatccgt agtcaaacac tctatccagt tgagctatgg gcgcatattc
    16321 aatttaaaaa aattataaat catttgaaaa caaaaagcaa gataaaaaaa atcgggaaga
    16381 caggattcga acctgcgacc ccttggtccc aaaccaagtg ctctaccaag ctgagctact
    16441 tcccgtttaa aaaataaaaa agac
//
LOCUS       DAFEIE010000058        16402 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFEIE010000058
VERSION     DAFEIE010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.060"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            374..3181
                     /locus_tag="LP345_002106"
     CDS             374..3181
                     /locus_tag="LP345_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1760877.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3372..3863
                     /locus_tag="LP345_002107"
     CDS             3372..3863
                     /locus_tag="LP345_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1760878.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3966..4955
                     /gene="manX"
                     /locus_tag="LP345_002108"
     CDS             3966..4955
                     /gene="manX"
                     /locus_tag="LP345_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBL1760879.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            4988..5791
                     /locus_tag="LP345_002109"
     CDS             4988..5791
                     /locus_tag="LP345_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBL1760880.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5812..6726
                     /locus_tag="LP345_002110"
     CDS             5812..6726
                     /locus_tag="LP345_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBL1760881.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6809..7183
                     /locus_tag="LP345_002111"
     CDS             6809..7183
                     /locus_tag="LP345_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBL1760882.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7322..7567
                     /locus_tag="LP345_002112"
     CDS             7322..7567
                     /locus_tag="LP345_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1760883.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7739..8803
                     /locus_tag="LP345_002113"
     CDS             7739..8803
                     /locus_tag="LP345_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL1760884.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9049..9474
                     /locus_tag="LP345_002114"
     CDS             9049..9474
                     /locus_tag="LP345_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1760885.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9467..9916
                     /gene="nusB"
                     /locus_tag="LP345_002115"
     CDS             9467..9916
                     /gene="nusB"
                     /locus_tag="LP345_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBL1760886.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            10013..10867
                     /locus_tag="LP345_002116"
     CDS             10013..10867
                     /locus_tag="LP345_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBL1760887.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            10868..12205
                     /locus_tag="LP345_002117"
     CDS             10868..12205
                     /locus_tag="LP345_002117"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBL1760888.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            12210..12434
                     /locus_tag="LP345_002118"
     CDS             12210..12434
                     /locus_tag="LP345_002118"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBL1760889.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            12436..13326
                     /locus_tag="LP345_002119"
     CDS             12436..13326
                     /locus_tag="LP345_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL1760890.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            13335..14153
                     /locus_tag="LP345_002120"
     CDS             13335..14153
                     /locus_tag="LP345_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBL1760891.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            14260..14709
                     /locus_tag="LP345_002121"
     CDS             14260..14709
                     /locus_tag="LP345_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL1760892.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            14727..>16402
                     /gene="recN"
                     /locus_tag="LP345_002122"
     CDS             14727..>16402
                     /gene="recN"
                     /locus_tag="LP345_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBL1760893.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAK"
BASE COUNT         5429 a         2716 c         3691 g         4566 t
ORIGIN      
        1 aaaataaaag ttgtagtgga ggctacgaag tttactttgt ctttttacac ttaatatttt
       61 tttgccaatt tggaatcagg atgttttgat aactatcgtt ttcaattgat ggaagctata
      121 ttgtttgcta tcagtgaaat aattatatgg taaacagtgt tctttttctt gtttccatta
      181 taaaaatcgt atcgggattt ttcgttcttt taaattgaac atttctatct atccgcgtgt
      241 tatcaacaaa acaaaatcag gtaaatagtt gacgaaacag aaataaatac atagtattat
      301 gttttgaagc ctaagtacaa tagtctatag aaaaggagcg ataccattgg caaaacgcat
      361 tgaccgaatt tatatgtatg tcaaagaaaa aaccgctcat ttaacaaagg cagaatatga
      421 tcaaggagta acaacacagg aaattgctga agtgttaggg attcagcgaa caaatagcag
      481 taaagatctg aatcagctag tgcgcgaagg aaaactgata aagacagacg gacgaccagt
      541 acgttacata tatcaaacac tcgttacgca cgtaaagcca gttacaaaac atgtagtcag
      601 ttacaaagaa acgccggtct ctgaagaaaa aaatacactc caaatagata ctaaggatat
      661 ctttgcaaaa atcattggag ctaacggcag catgaaaaat tcagtggaac aggcaaaagc
      721 tgcgattttg tatccgccaa gaggattaaa ttgtttgatt acaggaccta ccggatcagg
      781 aaagacttat tttgcacacg cgatgtatca ttttgcaaaa gcgcatcatg taatagatga
      841 ggaaacggaa ctgattgttt tcaattgtgc tgattatgcc aataaccctg agcttttgat
      901 gagtcattta tttgggtacg caaaaggtgc ttttacaggc gcagatgaag aaaaaatggg
      961 gattatcgat caagcggatg gcggtatgct gtttttggat gagattcacc ggttgccgcc
     1021 tgaaggtcaa gaaatgatct tttactttat ggatcatgga acttacagtc gtcttgggga
     1081 aacaacgaaa tcccatgaag caaatgtacg gatcgtaggt gcgaccacag aagacccagg
     1141 ttcttctcta ttagaaactt ttgttcggcg tatcccaatc aatatcaaac ttccggcttt
     1201 tgaaaaacgt cctgcaaatg agaaagtcga tttagtaaaa atcatgattg cccacgaagc
     1261 aaaccgcacg cagcgaaaga tttctttgac agaagatgta gcaaaagcat tgatcggcag
     1321 tgtgacctat ggaaatatag gacaattgaa gtcaaatatc cagttagtat gtgcacgagg
     1381 atttctaaat catatgcaat cacccgaaat ctcgatcaca atcgatgatt tgacagaagg
     1441 gattcgtagc ggattgattc aattagcaag caaccgcagt gcaatggcag agctttctaa
     1501 aatattggag ccaaagataa ctgtagcacc aaatgatacg atcatgaaaa tccaatcgga
     1561 ctcctatgag ttaccttata atctatatga tatcatcgga gataaagcag ctttactgaa
     1621 gtcggatggt ttggatcaag aagcaatcaa tcatttcatt tctacagata tcaacatcca
     1681 tctgaagtct ttctataaag accatggttt ttcttttaat gcagacagca aattagcaga
     1741 atttgtagat ccgaaaatca tagaagtgac caatcagatt tatgtaatgg tcaaaagatc
     1801 tttaccatat gagtttcagc aaaactttat ttatgctatg agcttgcata tcagttcttt
     1861 tttgaaaaaa atcaacttag gagaagaacg gcatacgaat gataacatcc gtgagatggc
     1921 ttttgatttt ccagatgaat atgctgttgc gaaagaagtg cgtagttata tcgaaacgta
     1981 ttttcaagtg gagattccag aaagtgaaga ctattacttg accgttctac tcgtctcgtt
     2041 acgggcaaat caagcaagcg gcagaatcgg tgtagtcgtt gcagctcacg gaaacagcac
     2101 agcaagcagt atggtccaag ttgtccaaca gttgttagat gcagagaacg tacgagcagt
     2161 agacatgcct ttggatatgg atccgaaaac agcattggac cgaattgaac gcaatgtaca
     2221 agaagtagat gaaggaagcg gggtcatact cttagtagat atggggtccc ttgcgtcgtt
     2281 taattcgcaa attcaaagag acactggaat tccagtacgt actgttgata tggtaacaac
     2341 ttctctagtt ttggaaactg tacgaaaggt ctcagtatta gggacagatc tagatatgtt
     2401 gcatgaatca ttgaaaaatt ttcgaggtta cgcagaaata tcttctgtag aatctgttca
     2461 ggaagcaaaa cctattcata agaaaaaagc tgttttggct atctgcgcat ctggcgaagg
     2521 tacagcacaa agaatcaaag aattgatcga acgagcggta aacaagcgtc aagaaacaga
     2581 attagaagtt ctagctttgt cgattgtgga agtgaaagaa gaactgccag ttatccaaaa
     2641 agaatatcag atcatagcta ctactgggat tactgatttg aatatccaag ccccatttat
     2701 tcctttagaa cgttttattg atcaaaatat cgaagtcatt ttggatcagt tgctgatgga
     2761 atcagaattg gaggaaactg aattcatctc cctagatgaa gagtcagcta aaaatacgtg
     2821 tgttgagttt atctctgata acttcatctt tattaatggt agtaagttaa tcgatccaat
     2881 gtggcaattt tctacacaaa tctctcagac gacgggaatc ggcgatgaag aatatggatt
     2941 caaaatcaac ctagtgatgc acacagcagg aatgatcgaa cgtattattc ggaatgaacc
     3001 attgactgtg gaagaaaacg aattgacaaa tacaacgaat gatcctcttt atagccaatt
     3061 ggcagcctca gttgttctgt tggaagatca gataaaagta aaagtgccga tagaagaaat
     3121 gtattatctg ctacgtctag tccataatca gttagataaa aaagaataca ctgtgccatg
     3181 aatacacaaa aacgatacac ttttatagtg tatcgttttt gtgtattggt taagaatcct
     3241 ttaaattcaa ttagtgtatc gtaaaaaagt tggcacgctt tttgcttata gtagtgtgtg
     3301 ctaggaggtg gttgttcaca cagaaatgat aggggtttct gtgaagtagt gaggaagaag
     3361 gagttttgca gatggatatt cgattggcac gtatagatga tcgtttaatc cacgggcaag
     3421 tcgcaacagt ttggtcgaag caaacaggtg ttgaacgtat cattgtgatc agcgatgtag
     3481 tcgctcaaga taaattgaga aagtttctac taaaagaagc tgcaccgccg gggatcacag
     3541 caaatgtaat aaccgtgcag aaaatgattc aaatctatca tagtggatta ttatcacgag
     3601 caaaagtgat gcttttattc accaatcccc aagatgttga agcggttgtc cgctgcggtg
     3661 tacagttgaa gtcgttgaat atcggcggta tgagttttac tgaaggcaaa tcaatgatta
     3721 ccaattttgt ttcagtaaat caacaagata ttgattcctt tcgttacttg aacagtcaag
     3781 aagtggagtt agagattcga aaagtacctg ctgacaggaa aatccttttg atggaactac
     3841 tagcgaaaat caaaaaggtg tagcaagaat ggttgttgga aaaggtcaaa taattctgtt
     3901 gtaatggtta gcaattatta atatttttga atttgttaca acaaaagtaa ataggaggta
     3961 taaatatggt agggattatc ctagcaagtc atggacaatt tgctgaagga atcttacaat
     4021 ccggttcaat gatctttggc gaacaagaaa acgtcaaagc cgtgattttg aaaccaagtg
     4081 aaggtccaga tgacttgaga gccaaattgg aagaagcggt tgcttctttt gataatcaag
     4141 acgaagtgtt attcttagtt gatttatggg gcggaacacc gttcaatcaa tcaaacacat
     4201 tattcgaaga gcacaaagat aaatgggcaa tcgtcagcgg tttgaattta ccaatgttga
     4261 ttgaagccta cgcatcacgc ttttcaatgg aatctgctca tgaaattgca gcacacatca
     4321 ttgaaacagc aaaagacggt gtaaaagtaa aaccggaaga attagaaccg gcagaagcac
     4381 cgaaagcagc agttgaagac gcacaaccta aaggagcact tccagaagga actgtggtcg
     4441 gagacggaaa aatcaaatat gtattagcac gtgttgactc acgtctgtta catggacaag
     4501 ttgcgacagc ttggacaaaa gcagtgcaac caaaccgtat tatcgttgtt tcagatgcag
     4561 tatcaaagga tgatctgcgt aagagactaa tcgaacaagc tgctcctcca ggtgtaaaag
     4621 caaatgttat tcctattagc aaaatgatcg aagtagcaaa agaccctcgt tttggaaata
     4681 ccaaagcatt gcttttattt gaaaatcctg aagacgtatt gacagctgtt gaaggtggcg
     4741 tagacatcaa agaattaaat gttgggtcaa tggcgcattc ggtcggtaaa gtcgttgtaa
     4801 gtaaagtatt gtctatggga caagaagacg ttgaagcgtt tgagaagctt gaacaaaaag
     4861 gtgtgaaatt cgatgtacgt aaagtaccta atgattcacg cgataacatg gatgatattt
     4921 tgaaaaaagc aaaagctgaa ttagcaaaag cgtaataaat aatattaaaa tttataggag
     4981 gcttatcatg tctattattt caataatttt agtcgtatta gttgcctttc tagctggtat
     5041 ggaaggtatt cttgatgaat ttcaatttca tcaaccacta gtggcatgta cattgatcgg
     5101 tttagttacc ggtaacctcg aagctggtat cgtacttggc ggtacgcttc agatgatcgc
     5161 tttaggttgg gcaaatatcg gtgccgctgt agcaccagat gctgcattag catcagtagc
     5221 atcagcaatt attttagttt taggtggaca aggtgttaaa ggtgttcctt ctgcgatcgc
     5281 gattgccgtt cctttggctg ttgcagggtt gttcttaaca atgatcgtac gtacaatcgc
     5341 tgttccaatc gttcatttga tggatgcggc tgctgaagaa ggaaacatcc gtaaggttga
     5401 aatgtggcac atcattgctg tatgtttaca aggggttcgt atcgcggtcc cagcagcagc
     5461 gttgctattt atcccagcac aaactgtgca atcattcctt gaatcaatgc cagcatggtt
     5521 aacagatggt atggctatcg gtgggggaat ggtcgtagct gtaggttacg ctttggtaat
     5581 caacatgatg gctacaaaag aagtatggcc attcttcgtt attggtttcg ttgtagctgc
     5641 aatttctcaa ttaacattga ttgctctagg tgctttaggt gttgcattag ctcttattta
     5701 cttgaacctt tctaaaatgg gtggttcatc aaataatgga ggcggaagca actctggtga
     5761 ccctttaggc gacattttga atgactatta atcttgaagg aggaaaataa aatggcagaa
     5821 gaaaaaatca aattatcaaa aaaagatcgt ttagctgttg cgtggcgctc taccttcatt
     5881 caaggttcat ggaactacga acgtatgcaa aacggtggct gggcattttc tatgattcca
     5941 gcaatcaaaa aattatacaa aacaaaagaa gaacgttctg cagcattaaa acgtcacttg
     6001 gaattcttta atacacaccc atacattgct tctccaattt taggggttac attggctctg
     6061 gaagaagaac gtgcgaatgg cgcgcctgtt gatgatgtag cgattcaagg ggttaaagta
     6121 ggtatgatgg gtcctttagc tggtgttggt gacccagtgt tctggtttac agtacgtcca
     6181 atgctaggtg cactaggtgc ttcattagct atgggaggaa atatccttgg accaatcatc
     6241 ttcttcttag gttggaacat tattcgttgg gcattcatgt ggtatacaca agaatttggc
     6301 tacaaagctg gttctaaaat tactgatgac ctttctggcg gattgttaca agacgtaaca
     6361 aaaggtgctt caattttagg gatgttcgta ttagctgccc ttgtacaaag atgggtatca
     6421 atcaaattct taccagttgt atcaactgta aaattagata aaggtgctta catcgaatgg
     6481 gataaattgc cttcaggtgg tgaaggaatc aagagtgcat ttgaacaagt taataatggc
     6541 ttagcccttt ctcctgaaaa ggtaacaaca ttacaagaca acttagacca attgattcct
     6601 ggtttagctg cattaggatt aacattgtta tgtatgtggt tgcttaagaa aaaggtttct
     6661 ccaatcgtta tcatccttgg tttattcgta gtcggtgttg ttggacacgt catcggactt
     6721 ttataatcca taaaaatata gctcgggcgt tgtcccgagc tttttttata tagtatactg
     6781 ttcataaaca aatatctgga gggagaaaat ggttcaatca atcaatacaa aagtagactt
     6841 ggtaattgat gctacttcgt ttacgggtct gacagattac gggcaaatca tgataggtga
     6901 taatggtttt gagttttacc atgcgcgaga tagacgcaaa tatatccaaa ttccatggga
     6961 agaagtggat tatgtactag catcagtcat gctaaaggga aaatggattc ctcgatatgc
     7021 cattcaaacg aaaaaaaatg gtacatacac attttcttcc aaagaaccta aaaaagtgct
     7081 tcgtgcgatc agagaatatg tagatgaaga tagaatggta caatcattga gtttctttga
     7141 tgtagtgaaa cgtggtattc gtagtatgtt taaacgcaag taaaaaataa agaaaacttc
     7201 taagaggagg ttttctttat ttttttactt tgcagaagaa aatatgaaat agcaaaacca
     7261 attatttgtc ccctttaaat cccatatgct aaaattgatt agcaaagaag gaggttatat
     7321 tatgagttgg ttatggacat tgattgttgg agccgtgatc ggagcaattg caggtgcgat
     7381 caccagtaaa ggaaattcga tgggctgtgt aacgaatatc attgctggac tagtcggttc
     7441 aagtattgga caagcgattt tcggcgaatg gggaccaaaa gctgcaggta tggcacttat
     7501 tccatctatt ttaggcgcag tgattttggt agcagttgtc tcatttttct ttggaaaacg
     7561 atcataagtt tttacaaaat agtaaactaa aaggagttgc agcgagactg tgactccttt
     7621 ttggctttat ttatttaaaa taaaaagaag ttttccggaa atttttattt aactgtcgtg
     7681 tacgaagaaa agtttgctat aatggaaaaa agcgtgcaaa gaaagaggga gtttcattat
     7741 gatgctacgt gtagaaaaat tgcgcaaaaa aatgcaagaa gaaaatttgg attcattttt
     7801 ggttaccagt ccgtacaatc ttcgttactt aacgaacttt acaggtacga caggattagc
     7861 tgttattact ttggaaaaag cattttttat tactgatttt cgttataccg agcaggcggc
     7921 agcgcaggct caagggtttg aaattattaa aaatgtcgga cctatttttg atgaggtagc
     7981 aaacttagta cgcaaagaag aactgcactc attagctttt gaggaaacaa cagtctcatt
     8041 tttagaatat tcggttttag aagaaatcat cgatgcggaa ttagtacctg tttcacagat
     8101 gatcgaagaa ctcagagaag tgaaagatga agaagaaatc gctattatcg aaaaagcatg
     8161 tcatattgcg gatatggcat atgatcacat cctgaaaatg atccaaccgg gcatgactga
     8221 gattgaagtc gcaaatcaac tagactttta tatgcgttct cttggcgctt caggtgtttc
     8281 ttttgatacg atcgttgcta gcggattgcg ttcggctatg ccgcatggtg tagcaagcaa
     8341 aaaaatcatc gaacaaggtg acttgatcac attggacttt ggttgctatt acgaagggta
     8401 cgtttccgat atgacacgta cattcgctat tggtgatcct ggggaaaaat taaaagaaat
     8461 ttatcaaata gtcttagatg ctcaattagc agttattgat gctgcaaaac caggaatgac
     8521 tggtgtccaa ttagatgcag ttgctagaga ttatatttca aaacatggtt acggggaagc
     8581 atttggacat tctacaggac atgggatcgg tttagagatc cacgaaggac caaacgtttc
     8641 ttctcgtgca gaaaagcaat ttgtaccagg aaatgtgatc actgatgaac cagggatcta
     8701 cttaccagga atcggtggag tacgtattga ggatgacttg ttgatcacag aagatggaaa
     8761 tcgtgtgttg actcgttcac caaaagaatt gatcatctta tagtttcatc aatagaagaa
     8821 gtaagcgtaa aaatcagtgt tcacagactt tgttatagaa aatcactcga tttaatgata
     8881 cactatagaa gaacttttaa gctgtaagag ataataaagt tgggtgtttt ctccaattca
     8941 tagcagtttg cagctgatcg gcggcagttt tcttaccacg tgatcactat gccgcatcat
     9001 agagaattcg gatgtatctc gtgcttaggc aaagggagga ataaataaat ggcagatgaa
     9061 aaaaatttga ttttaaacgc aaaccaagat ttaggagaga tcgtgatcgc tcctgaagtc
     9121 atcgaagtaa ttatcgggat tgcagcttct aaagtagaag gcgtatacgg aatgcgcgga
     9181 acttttgcca gcaatgtcac tgaattatta ggacgtgcag ctcacggaaa aggtgtttac
     9241 ttagcaaacg aggaagatgg cttgaaagta gatctttact gttatctaga atatggtgtt
     9301 tcagttccta aagtagcaat ggaaatgcag gaacgggtca gccagcaagt ccttttcatg
     9361 acggatatcg atttatctga agtcaatatc catgtagtag ctgttgttcc tgaaaaatta
     9421 gaacaaccaa caatcgaaga actttttgaa gacgaagagg aagagaatga ataaagaatt
     9481 atcaagacac gagattcggg aaatggcatt gcaggcttta tttccattag acttcaatgc
     9541 agacctaaca aaagaagatg cgattttcaa cgcaatcgaa ttagaccacc gcgacatgat
     9601 caacgaagat gaatcagagt ttgttcctgt ttatcttgat acgctagttg gcggtgtctg
     9661 tgcaaaaaaa gatgaattgg ataaagtgat tgaaaaacat ttaaaaaaca attggcacat
     9721 caatcggatc tcaaaaatgg atttggtgat cttgcgtatc gcgatttttg aaatgactta
     9781 tgtgacagat gtaccagcgg ctgttgcttt aaatgaagca atcgagttgg caaaaacatt
     9841 tagtgatgac cgttcacgta aattcgtcaa cggtgtttta tccaatgtat tgaaagaatt
     9901 agaagctggg gcgtaagtcc tagctttttt ctatgaatca tcataaacct gttataaatc
     9961 gggaaaattc tatggtagaa tgaaaacaca aaaaatatct gggagtggtt agatggcaga
    10021 attgattaac ggaaaagaat tagctgaaaa aatgcaggca gagattgctg aaaaaatcca
    10081 aaaattgaaa gataatggta tccatcccgg attagtcgtt ttattggtag gggaaaatcc
    10141 agccagccaa atctatgtaa gaaataaaga acgtgtagca aaagaaatcg gaatccattc
    10201 attggtagag cgttatcctg agacgatttc tgaagacgaa ctacttgcag aaattgaaaa
    10261 atacaatcaa gatcctagtt ttcatggtat attggtccaa ttaccattgc caaagcatat
    10321 agatgaagaa aagatcctgt tagctatccg ccctgaaaaa gacgtagacg gttttcatcc
    10381 gatgaattta ggcagactcc ttgcgggtaa accggacaag attccttgta ctccatacgg
    10441 catcatgaaa atgtttgaag cttattctat cgatccggcg ggtaaacgag cagtagttat
    10501 cggacgaagc aatatcgtcg gtaaaccgat ggctcagcta ctcttgatgg cagatgcaac
    10561 tgttactgtt gctcattcta aaaccgaaaa tctggctgaa ctggcacaag aagcagatat
    10621 tttagtcgta gcaataggac gtggacattt tgtcacaaaa gaattcgtaa aaccaggtgc
    10681 tgtagtgata gatgtaggga tgaatcgtga tgctaacggt aagctgatcg gtgatgtgaa
    10741 atttgatgaa gtggagccta ttgcaggctg gatcactcct gtgccaaagg gtgtagggcc
    10801 aatgactatc acgatgctga tgtatcaaac cgtaaaatct gccgaagctt ttggagcagg
    10861 tgaatagatg gcacaagaat atttaactgt cactacatta acgaagtatt tgaaaagaaa
    10921 atttgatgcc gatccttatt tagaacgcgt atatttaaca ggcgaaatat cgaatttccg
    10981 tttacgtgcc aatgcccatc aatatttcag cttaaaagat gaccatgcaa aaatatctgc
    11041 tattatgttc aaaggagcat tccaaaaatt acgattccag ccaaaagaag gaatgaaagt
    11101 ccttgtcgtt gggcgtattt cattatatga agcgggaggt tcttatcaaa tctatgtaga
    11161 gcacatggag cctgatggaa taggtgcttt atatcaagaa ttggaagaac gaaaagaaaa
    11221 gctgatgaag gaaggccttt ttcaagggcc taaaaaaatg ctgccacgtt tcccaaagcg
    11281 aatcgcggtc cttaccagtc caagcggagc ggttatccgc gatatcatca cgacggtgaa
    11341 aagaagatat ccaattgtcc aattggtttt gttcccaaca gttgtacaag gaaaccaagc
    11401 agcggacaat gttgtcagga atatccagag agtagaagag atgggcaatt tcgatacaat
    11461 gatcatcggt cgtgggggtg gttcgattga ggatttatgg ccgtttaatg aagagcgggt
    11521 tgctcgggcg atttatcaag ctaatacgcc ggtgatttca tctgtaggac atgaaacaga
    11581 taccacgatc gctgatttag tagcagatgt tcgggctgcc actccaacag cagctgcaga
    11641 attagctgtt cctgttttgt cagaagagtt gatgcgcatt caagaacggc aagctagatt
    11701 gcagcaggcg tttgtacgcc agatccagcg caaacaagaa cggttcgagc gtgctcgacg
    11761 ttcctatgta tttcggcagc ctgaaagatt gtatgaaggt cagaccatca aattagacca
    11821 gttgaaacag cgattatatc aagctacaca gcaaatttat catgcgaaag aaaaacaaac
    11881 gatcgcatta agccaccaat tggaacaagt ggctccgctt tatcgagtta aagcagctcg
    11941 ccaagaaact gcttatctag aaaaacgctt agaagagaaa atccaacaat atatgaaaca
    12001 acagcagcag cgttttgctc aagctgttca atctcttgat ttgttgagtc cattgaaaat
    12061 catgggaaga ggctacagct atacgacgtt aaatgatcaa gtagtaaaaa gtgtcaccga
    12121 gattcatcaa ggggatttgc tgacgatcca ttatcaagat ggaatcgtta aaggacaagt
    12181 acaagagata gacaaaggag aataaaaata tggaaaatcc aacttttgaa gagtcactgc
    12241 aagaattaga aaaaattgtc atgcagttag aacaaggaga cgttccatta gaatcagctc
    12301 tagattcgtt taaacgagga atggaattaa gcaaacattg ccaagataca ttagctaaag
    12361 cagaagagac cttgacgaaa atgatgacag aatcaaatga agaagttgat tttgacggaa
    12421 acgaggaaag ctgagatgag attaactgac ttttcagcta ttcatctacc tgctgtagaa
    12481 aaagaaatct tgtctttttt agatgagcat acaacggata gaggactcta tgatgcgatg
    12541 agttattcag tgaaagcagg cgggaaaaga atacgtccct tattactttt aacggccgtt
    12601 gcttcctttg atgagcctat tgatgttccc gtctatcaag tagcagctgc tttagaaatg
    12661 gtgcatacgt attccttgat ccacgatgat ttgcctgcga tggacaatga tgatcttcgt
    12721 agaggaaaac ctaccaatca taaagtattc ggcgaagcat tagctatatt ggccggagat
    12781 ggtttgctta caggagcatt ccagctaatc agtatggcac acttaggtaa ttctcctaag
    12841 cttctgctgc ttcagcaatt agctgtttgt gcgggatcac aaggtatggt tgctgggcaa
    12901 gctgcagata tcgagggcga atcgaaaaag ctttctttag aagaattagc atttattcat
    12961 gaaagaaaga cagggcattt gattcgttat gccttgctgg ctggtggcat attagcgaag
    13021 caacctgaag aaatcttatt gctacttcaa cgattagccg aacatttagg tttagctttt
    13081 cagataagag atgatctact cgatgtgatt ggtacaacga aaacattagg gaaaacagct
    13141 ggtaaagatg aacgtatgga aaaaaatact tacccgcgtt tattaggcct agaaaagaca
    13201 cgtgaggcgt tggagattga gctgttatcc gccaacaaga tcatagacaa attagaagag
    13261 gacgtttttt cttttgatgg cgggctgatg cgccagatga tcaagcaatt tgatgtggag
    13321 aaatgaggga aagaatggaa aaagaacgcg tagatgtatt agcggtcaaa caaggattat
    13381 ttgaaacaag agaacaagcc aaacgttcag tgatggctgg tttgatttac aacgaaaaaa
    13441 acgagcggtt tgataaaccg ggagaaaaaa ttccagtgag tagtgaatta agagtcaaag
    13501 gtaaaaaact tccttatgtt tctcgagggg gattaaaatt agaaaaagca ctcaaagcat
    13561 ttgatctatc tgttgaagga aaaacattgt tagatattgg tgcatccact ggcggattta
    13621 ctgatgcagc tttgcaaaat ggcgcaaaaa tgagttatgc tttagacgtt ggctacaatc
    13681 agctagcttg gaaaataaga caagatccta gagtcgtcgt aatggaaaga gtgaattttc
    13741 gttatgcaaa acccgaagac tttaccttag gaattccaga agttgctgtt atcgatgttt
    13801 cttttatttc actaaaactg atgctgcctc cattacatgc tattttaaaa gaagagggag
    13861 aagtgattgc tttaatcaaa ccccaattcg aagcaggcag agaagctgta gggaaaaacg
    13921 gaattgttcg tgaccctcag acccatcaaa aagttttaga agacattttg tcatttgcgg
    13981 cacaaggtgg atatgatgtg ctggaattaa gttattctcc gatcacgggg ggagaaggaa
    14041 atatcgagtt cttggctcac ttgaggaaag tacccgaaag cggaacaatc aattcagcta
    14101 ttaatatggc agaagtggtt tcaaatgcac acgaacagtt tgaccataaa taaattgtaa
    14161 ctgtgaaaat caagtgagaa gtatgcggat tcttctttat tataccaagg aaataagcta
    14221 tcattgatta agaagaatat gctaaggagc gaagacgtaa tgagaaaaaa agatcggcat
    14281 cgtttgatta ctcgattgtt gagtgagcaa gatatccgaa agcaggaaga atttgttgaa
    14341 atcctgaaaa gcaaaggaat atctgttact caagctacga tttccagaga tataaaggaa
    14401 ctgaaactga tcaaggtacc ggcttcagat ggcggctacc gttatagcat accagctgaa
    14461 acaaacgaag atgtaaatac taaattggaa aaactattaa aagacgcttt cgtggcagtt
    14521 gaccaaatgg aaaaatttgt tattttgaaa acattgccgg gaaatgcttc ggcagcagca
    14581 aatttgattg ataaacgtta caagaaagaa ttattttcga ttatcaatga tgacgataat
    14641 gttttgatga ttacacgaac tgaagaccag gcagttttat tgaagaaaga cttcctgcat
    14701 tacctttaag ttgaggagcg aatgtgatgc tacaagaaat cagtattact aactttgcga
    14761 ttattccgga attgcggctt tcttttcacg aaggaatgac cgcgctgacc ggagagactg
    14821 gtgcgggtaa atccattatt atcgatgctt taggtctgtt agcaggagga agaggttcaa
    14881 gcgattatat acgtcaagga gcagaaaaat gtgtgcttga agggttgttt gaactaccaa
    14941 aacaagaagg attctctgaa ctgatggttg aattagggat cgaaacagat gaggacaatc
    15001 tgattgttcg acgggatatg tccttaactg gaaaaaatgt ttgtcgagtg aatggtcata
    15061 ttatcacatt agctaatctg agaagaatcg gcagttattt agtagatatc caaggacaaa
    15121 acgaacatca ggaactgctc cagcctgaat cacatcttgc tttattggat cgttttggag
    15181 atgtagcttt ccaacagaag aaaaagagtt atcagcaaga atatatctct tatcgtgagc
    15241 tggaaaaaag ggtacgaaaa gtgcagcaaa atgaaaaatc ctatgttcag agaatagata
    15301 tgctccattt ccagcaagaa gaaatagctg ctgctgattt gcaagtcgga gaagaagaga
    15361 aattaaaaga agaaagagaa aaacttagca attatcaaaa aattgctgat ggattagctg
    15421 caggttacgg agcactgacg aataatgaac aaaacagtgt agatggtgtt ggcttggccg
    15481 tttcagaact gcaagggatc gcccatctag atgtggagta tgaagcaatt tatgaaaata
    15541 tccaaagtgc ttactatttg ctgcaagatg caatcggcga tatgagtcgt cagattgatt
    15601 tattggagtt agatgagagt cgtttagaag aagttacgca acgtttagaa ttaatccgac
    15661 agttgaaacg taaatacggc gaatccattg agtcaatatt ggcttactat gacgaaatca
    15721 ccgaagagct agcttcttct gatttttcag aaggtcaatt ggacaaaatg aaagaggaac
    15781 tagagcaaaa agagcttcta cttcagcaac aagccgcaga tcttcatgaa gcgcgtaaaa
    15841 aaatcgcaaa agaattggaa aaatccattc tgcatgaatt gaaaagtctg tatatggaaa
    15901 acactgagtt tgaggtacgt ttcttaaaag aagaaaatag acaattgaat catgatggat
    15961 ttgaccaaat cgaattttac attacgacca atccaggaga gccactgaag cctttggtga
    16021 aagtcgcttc tggtggcgaa ctgtctcgga tgttgcttgc tttgaaaact attttttctt
    16081 ctgagcaagg tgtgacaagt attatttttg atgaagtgga tacaggtgtg agcggaagag
    16141 ttgcacaggc catcgcagat aaaatttctc aaatatcgaa atactctcaa gttttgtgca
    16201 tcactcatct gcctcaagtt gctgcagtcg ccgactatca atattatatt gtgaaagcag
    16261 tgattgatgg acgtacgcaa acttctgttt cagagttgaa aacaaaagaa agagaagaag
    16321 aaattgcacg tatgctggct ggaagtgaga ttacaaaact cacactcgaa catgcaaaag
    16381 aactattgaa actcgcaaaa ag
//
LOCUS       DAFEIE010000059        15850 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFEIE010000059
VERSION     DAFEIE010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.061"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            293..1432
                     /locus_tag="LP345_002123"
     CDS             293..1432
                     /locus_tag="LP345_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBL1760894.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1499..2074)
                     /locus_tag="LP345_002124"
     CDS             complement(1499..2074)
                     /locus_tag="LP345_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1760895.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2079..3053)
                     /locus_tag="LP345_002125"
     CDS             complement(2079..3053)
                     /locus_tag="LP345_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBL1760896.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3077..3121)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3336..4304
                     /locus_tag="LP345_002126"
     CDS             3336..4304
                     /locus_tag="LP345_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1760897.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            4417..4695
                     /locus_tag="LP345_002127"
     CDS             4417..4695
                     /locus_tag="LP345_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL1760898.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            4813..5049
                     /gene="secG"
                     /locus_tag="LP345_002128"
     CDS             4813..5049
                     /gene="secG"
                     /locus_tag="LP345_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBL1760899.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            5152..5907
                     /locus_tag="LP345_002129"
     CDS             5152..5907
                     /locus_tag="LP345_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1760900.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLRW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5910..8267
                     /gene="rnr"
                     /locus_tag="LP345_002130"
     CDS             5910..8267
                     /gene="rnr"
                     /locus_tag="LP345_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBL1760901.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWATELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8289..8753
                     /gene="smpB"
                     /locus_tag="LP345_002131"
     CDS             8289..8753
                     /gene="smpB"
                     /locus_tag="LP345_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBL1760902.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9055..9774
                     /gene="atpB"
                     /locus_tag="LP345_002132"
     CDS             9055..9774
                     /gene="atpB"
                     /locus_tag="LP345_002132"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBL1760903.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9827..10042
                     /gene="atpE"
                     /locus_tag="LP345_002133"
     CDS             9827..10042
                     /gene="atpE"
                     /locus_tag="LP345_002133"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBL1760904.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            10133..10657
                     /gene="atpF"
                     /locus_tag="LP345_002134"
     CDS             10133..10657
                     /gene="atpF"
                     /locus_tag="LP345_002134"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBL1760905.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10644..11186
                     /locus_tag="LP345_002135"
     CDS             10644..11186
                     /locus_tag="LP345_002135"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBL1760906.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNKAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            11209..12765
                     /locus_tag="LP345_002136"
     CDS             11209..12765
                     /locus_tag="LP345_002136"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBL1760907.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12779..13681
                     /locus_tag="LP345_002137"
     CDS             12779..13681
                     /locus_tag="LP345_002137"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBL1760908.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13704..15110
                     /gene="atpD"
                     /locus_tag="LP345_002138"
     CDS             13704..15110
                     /gene="atpD"
                     /locus_tag="LP345_002138"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBL1760909.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15124..15546
                     /locus_tag="LP345_002139"
     CDS             15124..15546
                     /locus_tag="LP345_002139"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBL1760910.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         5263 a         2839 c         3418 g         4330 t
ORIGIN      
        1 ttttttttgc aactagcttc tgtatatgat gtttacaaag aatggtacaa gaaaagatca
       61 tccttgaaaa aggaaagcta acaataacta gcatcatata agagctttta aggatagaac
      121 agtagaatag gaatctatga gcaagtcctc tcgtataaat aaaataggag ggaagtagca
      181 gcatattttt cataaagtgg ctctctttct tcatttttac tttggttgct cctatttgaa
      241 aattcgagca cactcaaata caataaaaag aaatggcaag ggagaggatt agatgaaaaa
      301 agaagaaaaa atcgcgattt tacaagagat catccgaatt aaatcagtga atggaaacga
      361 aggtgaagta gcagcctatt tgaataagct tttggcaaag catgacataa caggagagat
      421 tgtttcttac agagatggta gagataattt gattgctcgt taccaaaagg gccaatcagg
      481 aaaagtgtta ggcctatctg ggcatatgga tgtcgtggcg gctggtgatg aatcgtcttg
      541 gacctatgca ccctttgcag cagaaatcca tgggaaccgt ttgtacggac gtggtgctac
      601 agatatgaag agtggcttgg cagcaatggt gattgccatg atcgaactga aagagtcagg
      661 aaaaccattt aacggaacag tcaaattatt agccactgtc ggagaagaag tgggtgaact
      721 aggtggggaa cagctcacga aagcaggcta tgtagatgac ttagatgcct tgatcatcgg
      781 agagccaact aattacagtt tgatgtatac gcacatggga tcaatcaact atacagtcac
      841 ctcgcacgga aaagaagcgc atagctctat gccagaccaa ggttataatg caatcaatca
      901 cctaaatgaa ttcattacga aagcaaatgc tgaaatgaat cacctcgctg aaacaatcga
      961 gaatcctgtc ctaggaaaaa caatccataa tgttacattg atcagtggcg ggaatcaagt
     1021 caacagcatc ccaagccatg cgcagctcca agggaacatt cgatcgattc cagaataccc
     1081 aaatgataaa atcattgcat tgctgcaatc aatcgtcaat gaattgaatc aagagacaga
     1141 ctatcatttg gaattgatga tcgattacaa caaaatacct gtcaaagctg atccagattc
     1201 tcctttgatt cattgcattc agcaacaatt cagccagcca ttacctttag ttggagcggc
     1261 agcaacaacg gatgcagccg aatttacgaa agctaaccat tccttcgact ttgtcgtctt
     1321 tgggcctggt gtcgttactt tgcctcatca agtagatgag tatgttgaaa tcgataatta
     1381 tttggatatg attgaaaaat atcaaggaat tattttatcc tacttagcgt aagatttttt
     1441 taataaatga aaaaacagag ccagattagc attattttgc taatccagct ctgtttattc
     1501 agcctatttt tctttttgaa tatatcaagc gttgtggcaa catagtgatg actaatgaaa
     1561 caacgacgat agacaacaaa cgatcaaggt agtctgtacc tgcctgtacc aagatcacac
     1621 ttgttgtctg acttaaacct aacccatgta atagctgaac gatcatactg gatcctgagg
     1681 aggtgatccc gccaaataac tgaacggtaa tgatcgaaga aacgatcgtt ccaggtaccg
     1741 acaaaatcaa agcgagtaat aacagtttca agctgttttt atctttgccg agatatcttg
     1801 gcaaaatcaa tccagcaagc aagcctgtga gaatttggat tggcgaataa tacagagaaa
     1861 aaatatctgt agtcactcca cttaaaatac cgctggacaa tcctgtcagc attccaggta
     1921 caggcccaag caatgcacca gcaaaaatcg ttccgataga atcgagatag attggcaaac
     1981 gaagccataa agcaatcgtt cctccaatat aattgatccc aatacacaaa gccatcactg
     2041 taagtacgcg agttgccatt ttgtttttat tcattttgtt agcccatctt taacctttcc
     2101 aaatctttca taatcgtttc ttcttgtgca tttaaaagaa cggttaaaaa ctttcggaaa
     2161 aaaagacgag tatctacttt tgtcataatt ttactgttag caggtttctg ccaaaattca
     2221 taacgatcaa ccaatgtttg tccacgactt attccttgag tttccacagc agtgaagctt
     2281 ttgaaacctt cacagatggc cccctcgata aaataagcaa cagctaacgg atcattgatg
     2341 acacatccta aaattctttc ttgtttccag tggaagtcaa aataaaaacg agtgatcgct
     2401 tttagatact ctccctcttc aggattcatt tgacagcagt attcgaggat agtcggtgtc
     2461 aagacgattt ctcttgtcac atctaaccca accatttcta tcgtttgttt gagattctcg
     2521 aatacataag aagctgcttc aggatcacac cagtaattgt attcagcaac tggcgaacag
     2581 ttaccatggc ttttgtaagt tccacccatc gagacaaaac gatccatatg tttcccaata
     2641 tttgggttga ctttcaaagc aaaagcgata ttggtcaaag gacccaaagc aatgactgat
     2701 gtatttgtct tttctttgaa ataatcagcc aaaaaatcaa cggcatggag aggttctgcc
     2761 tgttttctca agatcatcgg gaaatttgtt tcccctaaac catccatacc atgagtgtct
     2821 tgtgcactga tgaaaggttg cttcaaaggt ttttccattc cttgataaac aggaatgtct
     2881 aaacgatcac agcgttccag gcatttcagc acattctgcg tacctatatc tgcagggaca
     2941 ttcccacaaa ctacggtaat agcaactact tcgatatcag gggatttgac agctaatgat
     3001 aaagctaaag tgtcgtcgat ccctggatcg caatcaataa ttacttttcg cattatttcc
     3061 aatctccttt ctttagagat acttagtttt ttattctggg aagtttccga accagtccaa
     3121 gacgagcgtc ttgattataa tgcacgaaat tagtatactg gcttttattg cgaatgtaaa
     3181 tgctctctta caagtaaatc tattgaggag aactttaagt aaatgataca atgaaaaaga
     3241 aatggaattt acgtgtgccg aaaataaaga atcctatgga tcggtacatt ggataatagt
     3301 tagattatag tttggcagaa agcggcgggt gtacaatggt tattttttat ttcattctta
     3361 ttctgataat tatagggatc agttaccatt ttctttctta tttttatgca aagaaattag
     3421 taagagcggg agtacagaga ggatatgact ggtatgaaga cactggtcat cgtttgatgg
     3481 accctgctgc agtcacgtca gtagaaaaaa aacgacaaaa attagaagaa gagtgtgaaa
     3541 gcttttggga gcagggaaca cccaaaacaa tcaaaagtta tgacgggttg aaactagctg
     3601 gtcagatgtt catccatcca aataagcaga ataaatgggt catttgcgta catgattacc
     3661 gaagcacagg gaaaagagac atgtctcata taggtaaaag atatgcagag aaaggattca
     3721 acgttcttgt acctgattta cgtgcgcacg gagaaagtga aggagaaatc atcggaatgg
     3781 gatggctaga tcggctagat ttaattgcct ggatccaact catcttagat gaacagccga
     3841 atgcgtccat tattttacac ggcggatcaa tgggagcttc tacgatcatg atggcaagtg
     3901 gtgaaaaact tccatcagcg gtcaaaggat ttattttaga cagcggatat gtttctgttt
     3961 atgcagaatt ccgatatatg ttaagtaaaa tcactgtctt tcctaaaaaa atggtcatga
     4021 gatatgcgaa tcattatgcc cagaaatacg ccggttactc cttaaagcaa gcatcagcta
     4081 cgagacagct tggcagcaac catctgcctt tattggtcat tcatggtgaa agagatcatt
     4141 ttgtccctac agaagcagcg tacacgattc aaaatgctac ggcaggggat aaagcactgc
     4201 tgcttgttcc agaagcagaa cacttggaag catcgatgaa agatccgaaa acctattgga
     4261 cagtgatttt ttcatttatt gaacaaagaa taacgatgaa ttaattttct cttctttttt
     4321 gtaagtaatt cgaggataaa taattgttta tagatcagga gactgctaaa ataaggtagg
     4381 aataaaaaaa tatcagttat ttgaggagtg cggcatatgg aaatcaaaga agaaaaaaat
     4441 cgtcttgctt tattcaatga tgaacaacaa gagatcggag aaatgacatg gtcagatgcg
     4501 ggcccagaca tcatgatcat tgaccataca tttgtagatc cagcatatcg tggtcaaaag
     4561 ttagctgaaa agctagtgta tactggagta gaattagcaa gacgagacgg gaaaaagatc
     4621 attcctttat gcccttatgc aaaaaaagag tttgaaaaga aaccagaata tcaagacgtc
     4681 ttacgtcagt cataagaata acagctgaaa gttttgaact ttcagctgtt attccattta
     4741 tatagagttg tcacggactt ttatctatga taaagttaaa gagacgatat cttttgggaa
     4801 ggaggctgcg atatgtataa tttaattttg ggaatcgtga tcgttttatc gattgttatg
     4861 gtcattgcga ttatgatgca gccaagcaag caaaatagtg cagcgagtgc atttaccggc
     4921 ggtgcggatc aactattcgg caaacaaaaa gctcgcggct ttgaagctgt catgcagcga
     4981 tcaactgcag ttatgggagc tatctggatg atcttattat ttgtcctagc atatttatct
     5041 tcgaagtagt tgaataagcc tctcgcaaaa cggcgggcgg ctttttttat tgcaaagaga
     5101 acgcttaaga agaagttatg aaagaaacta tggtaaaatg aggcgaaaga ggtgagacga
     5161 gtgagacaat taccaaaacc cctttatgca aaacatggaa agcgagcggt tttgctgctt
     5221 cacgcttact caggaagtcc aaacgatgtt cgaatgctcg cacgattttt ggaaaaagca
     5281 gattatacag tttatgcgcc gctttttaaa ggacacggaa caatggagcc atatgatatt
     5341 ttgcaagaaa aagcagaaag ctggtgggca gacactaaaa aagccatcca ttttttacag
     5401 tctgagcagt tttctgatat tgccgtatta ggattatcaa tgggcggcat ctttgctgta
     5461 cgagcactag aagaagaatc agtgattggc ggcggttttt tctgttcgcc tttgtctcct
     5521 gtaaaaacaa acgtgcctga aaactttgaa aaatacgtac gtcaagtgct gaagacagca
     5581 ggtaaatcag agaaagaaat caatgaaaaa gcagttgctt accgctcgtt agctgaacaa
     5641 caattaatgg atatacaaga tcaggcagca atcgtagaaa gtaggttgtc agatatccaa
     5701 cagccgatat ttttagctca agctgggaaa gatgaaatga tcgaccctaa tggcgtattt
     5761 gaaactgcac gcaagttgag ccgtcagcga gtgacacttc gatggtatcc tgaaagtggt
     5821 catgtgatta cagttggtac agcaagacgc gaattagaaa aagacgtctt ggaattttta
     5881 gaaaaattac cttggaatga ggaataaata tgacaaaaga aacgataaaa gagaaaattc
     5941 tctttttcat ggaaagcagt cgcaaacgca gtttttctat ggaagaaatc gctgaaggtt
     6001 tagggttcca aaaaagcgat gattttaaat tactagtaca aacgattgct caaatggaaa
     6061 gagaacagag tatagttttc aataaaaaag gaaaagtgaa acttccttta aaaccaatct
     6121 tgatcgaagg aacatttcga gcaaatgaac gaggatttgg atttgtaacg attgatcccg
     6181 aagaagatga catctatatc ccaaaagaag cgactggttt tgcaatggat ggagacaccg
     6241 tagcaatcga tatcatgaag cgagcaaata cagatatgga tcgcggagca gaggggaaag
     6301 tagtcgagat tcgagaccgg gcgactactc agttagcagg ggaattcgtt gcttattcag
     6361 aagaagaaat acaagaaacg gatctttacg gcgttgttat cccgaaagat agaaagctca
     6421 accaatttaa agtatatgca gcagcagagg gagttcgtcc agttgacgga agtattgtgc
     6481 tgatcgaact gacccattac cctgaaaaag ggtatgcgac tagtttagaa gggataatca
     6541 agcaagtgat tggtcataag aatgaccctg gcatggatat cctctcaatt gtcgtggcta
     6601 atggtatccc tacgaaattt cctgatgatg tattgtctga agcagatgaa gttccagatc
     6661 aaatcagcga aaaggatata actggacgta gagatttaag aaatcagctc attgttacga
     6721 ttgatggaga agatgcaaaa gatctagatg atgcagttac ggttaaaaaa ttagataacg
     6781 gtaattattt tcttggagta cacattgcag atgtttctta ctatgtgaca caaggcagtc
     6841 aattggacag agaagcatat gaaagaggga caagtgtata tttgactgat cgagtgattc
     6901 cgatgatccc gcaacgttta tcgaatggta tctgttcact gaatccccat gttccaaggc
     6961 tgaccatgag ttgcgaaatg gagattgatc caaatggaca agtagtctct catgatattt
     7021 tcccaagtgt gatccaaaca acagaacgga tgacctacac agctgtcaat caaatcttag
     7081 aagatcaaga cgaagaaacg atgcaacgct atgctcagct cgtacctatg ttccaagaaa
     7141 tgggtgaatt gcatcgaatc cttgaaacga tgcgaatcaa acgtggcgcg atttcttttg
     7201 aggatcgcga agcaaaaatc cttgttgatg ctgaaggaca cccaaatgat atccagctaa
     7261 gaagcagagg aattggtgaa cgcttgatcg aatctttcat gcttgcggcc aatgaaacgg
     7321 tagctgaaca ttataataaa ttaaatctgc cgtttattta ccgaatccat gaacagccaa
     7381 aagaagaaaa aatgcagcgc ttctttgatt ttgcttcagc tttgggcatt ctggtccgag
     7441 gaacgaaagg aacgatcaca ccaaaagatt tacagcatgt gatcgaagga gtagaagaca
     7501 aaccagaagc tgcagttatc aatactatgt tgctaagaag catgcaacaa gcacgctatt
     7561 cagaagacaa ttttgggcat tatggcttag cggcagatta ctacacacac tttacatctc
     7621 ctattcgacg ctatcccgat ctaatcgtcc atcgtctgat ccgttcttac agtgaagata
     7681 aaagtgaaag caatcaaagt tcgtgggcta cggaacttcc tgaaattgca gatcatagtt
     7741 ctaagatgga acgtcgtgca gtagaaacag aacgtgaagt agattccatg aagaaagcag
     7801 aattcatgat ggacaaagtg ggggaagaat tcgatgggat catcagctct gttgtgaaat
     7861 tcggcctgtt tatcgaactg ccgaatacag tagagggatt gatccatatc aatgaattga
     7921 aacaggacta cttccatttt gttgaaaatc atttagctct tgtaggtgaa agaactggtc
     7981 tgacttttaa aatcggacag aaagtgcgag taaaagtagt caaagctgat ccagatgaac
     8041 gagcagtaga ttttgaactt gtttccgcag aagaggttac agcgttggaa cggccaaaaa
     8101 cacgaaatgg aaaatcagga aaacgcgaag gaaaacaagc aggaaaacgc ccagaaagaa
     8161 atggcaagaa gaacaaacga tatagcgata gtaagcaaac gttcggtaag aaaaaaggga
     8221 agaagccatt ttacaaaggt gttaaaaaga agaaaaagaa aaaataaaat gagttggagg
     8281 aaacagctat gccaaaaggc gagggaaaat taattgcaca aaacaagaaa gctcgccatg
     8341 attattcgat catcgacacg atggaagcag ggatggtctt gcaaggaacc gagatcaagt
     8401 cgatacgaaa cagccggatc aatctaaaag atggatttat tcgcgtccgc aacggagaag
     8461 ctttcttgca taatgttcat atcagtcctt atgaacaagg aaatattttt aatcatgatc
     8521 cgttgcgcac gagaaagtta ttattacaca aaaaacaaat catccggctt gaaaatgaat
     8581 tgaaaaatac tggaatcact gttgttcctt taaaagtcta tattcgtaac ggctatgcca
     8641 aggtattgat tggtctggcg aaagggaaaa aatcttatga taaacgggaa gatttgaaac
     8701 gaaaagatat cgatcgacaa attgatcgaa cattaaaaaa tttctctaga taatttcatt
     8761 atcctttttc gcatattcgg tgcttttgct tttacttaat gataaaattt gttagcattt
     8821 aatctgataa aacatgatta tcataggttt tttcttagat caggagcacc gtgtataaag
     8881 aaaaattcgc ttcgtttttg actgaaataa aaaagtgtct aattttcatg aaaatgtttt
     8941 gaattttctg tttcatggtg gtatgatacc gtgtggttag aaaccgattg gaaaaaacca
     9001 gatacgcaca tgaattgatt ttatgtgaat ttcggggaaa agaggtgaaa tggattggat
     9061 gaacgctcgc taacgttcca cattggacca atttggtttg atggtacagt ttgtataatg
     9121 gtgttactga cctgtttgat tgttttcttc ttagcttact tttttacaag aaatcttaag
     9181 ttgaaaccaa caggcaaaca aaatgcgata gaatgggtca ttgattttag tcgaggaatc
     9241 gtaacagata atctgcctag aaaagaattg agcaatttcc atttgttggc atttacattg
     9301 tttttatttg tttttgttgc aaacaacatc ggtttagtaa caaaaatcgt tttacctaac
     9361 gaaacaacac tttggaaaag cccgacagca gacccgtttg ttactttaac tttggcattt
     9421 ataatgatct tacttactca cttatttggg gtgaaaaagt taggcttcaa aggatatttc
     9481 gtaaattcgt tcttgaaacc atatagtttt atgtttccga tgaaactgat tgaagaattt
     9541 acaaacttat taacacttgc tttacgtctt tatgggaata tttatgcggg ggaagttttg
     9601 ctaaccttga ttgcaaaaat ggtaataagc ttaggctggt tctcattgcc gttagcaatt
     9661 ccattagaga tggtctggat cgcattctcc ttgtttatcg gaagcatcca agcatttgtc
     9721 ttcgttactt tatctatggt ttatatgagc cataagattg aagtggaaga ataatattcg
     9781 ttttaaaaac aaactactat ttatctaatt taggaggaaa acaattatga attatatcgc
     9841 agcagcaatc gcaatcatgg gagcagcaat cggagccggt tatggtaacg gtcaagttat
     9901 ctctaaaaca atcgaatcaa tggctcgcca acctgaaatg tctggtcaat tccgtacaac
     9961 aatgtttatc ggggtagctc tagtcgaagc tgttcctatc ttaggggtag ttgtcgcctt
    10021 gattctagtt tttggtgttt aattgaatca gtattaaggc agaaacaatt tggtttgtta
    10081 ctgctttttt acatgaaaac tagaagtact tcaaagaaag gaaggctcgc ctatgctgaa
    10141 tcaattggca attgcagaag ttggcaatgc gatgttagga aatgtcatcg ttgtcagcgg
    10201 ctcatttttg atactactgg ctctcttgaa gcattttgct tggggaccaa tcagcgatat
    10261 tttgaaaaaa cgtgaagaca agatcgccaa tgatttggat tctgcagaac aatctcgcat
    10321 caactcagcg aaaatggaac aagaacgcga acaacaattg ttagcctctc gttctgatgc
    10381 agctgatatc atcaaaaatg cgaaagaaag tggagaatta agccgccaaa atattttgaa
    10441 ggatgctcaa gaagaagcag ctcgtctaaa aagtaaagcc caagctgata tcactgtaga
    10501 acgtgattca gcgctgaact ctgtaaaaga cgatgttgca gaactatctc ttcaaatcgc
    10561 ggaaaaaatc ttgaacaaag aattatctcc agaaatgcac gaatcattaa tcaatcaata
    10621 tatcgaaggt ctaggttctt caaatgaaac tagataaata tacagtagga agacgttacg
    10681 ggaaagcttt atttgaactg gcgatcgatt caaataaagc agaagaaatt tatcaagatc
    10741 tcgtaagctt acgtcaaatc tatgaacaag tacctggatt aggtaatatg ttaagtgatg
    10801 ttcgtctaga acctcatgaa aaacgagaaa tcatggacaa gcttgttagt ggctatgatg
    10861 gaatcgttaa aaacttttta gaagttgttt atgcgtataa ccgaatggat gatcttttgt
    10921 tcatgatcga agaatatgaa cgtcgatatg atgaacatca aggtttgctg ttgggaagtg
    10981 tcacaacagc agttccactt tcagacgaac aacgaataca attagaaaag aatgttgcaa
    11041 aaacaatgaa ctatcaatca gtcgaattaa aacaaatcgt tgattcttct attattggtg
    11101 gcgcgattgt tgaagctaac catcgagtaa tcgacggaag cattcgcacg caattagaaa
    11161 atatgcgtaa tcaattaaat agatagtaca aagaggtagg tgaatcgaat ggccatcaaa
    11221 gcagaagaaa ttagtgcctt gattaaagaa caaattgaaa attatcaaaa cgtgctttca
    11281 gtcgaagaaa tcggtaccgt aacttatgta ggtgacggga tcgctcgtgc acatggttta
    11341 gaaaacgcga tgagtggtga gttgcttgaa ttttcaaatg gctcatacgg aatggcgcaa
    11401 aacttagaat caaatgatgt aggtatcatt atccttggcg atttcgagtc cattcgtgaa
    11461 ggagataaag taaaacgaac aggaaagatc atggaagttc cagttggaga ggccttgatt
    11521 ggacgggtag ttaatccgct aggtcagcca attgacggac taggtgaaat cgttactgac
    11581 aaagctcgtc cagtagaagc aatggcacca ggcgttatgc aacgtaaatc tgttaacgaa
    11641 ccaatgcaaa caggtctaaa agcaatcgac gctcttgtac caatcggacg cggccaacgt
    11701 gaattagtta tcggtgaccg taaaacaggg aaaacttcca ttgcgatcga tacgatcatc
    11761 aaccaaaaag gtcaagatat gatctgtatc tatgtagcaa tcggacaaaa agattctaca
    11821 gttcgtacac aagttgaaac attgaaaaaa tatggcgcaa tggattacac aatcgttgtg
    11881 aatgccggtg cgtctcaacc agcgccgttg ctttatatcg caccatatgc tggtactgca
    11941 atgggtgaag agttcatgta caacgggaaa catgtcttga tcatttttga tgatctttca
    12001 aaacaagctg ttgcttatcg tgaactttcc ttgctgcttc gccgtccacc aggtcgtgaa
    12061 gcttatccag gggatgtttt ctacttacac tcacgcttat tggaacgtgc agcaaaatta
    12121 agtgatgatt taggtggcgg ttcaatgact gccttaccat ttgttgaaac acaagctgga
    12181 gatatctctg cttatatccc aacaaacgtt atttcgatca ctgatggaca aatcttctta
    12241 gaaagcgact tgttctacgc aggtactcgt ccagcggttg atgccggact atctgtatct
    12301 cgtgtagggg gttctgcgca aatcaaagca atgaaaaaag ttgctgggac tttacgtcta
    12361 gacttagcaa gttaccgtga attagaagca tttacacaat tcggttctga cttggatgca
    12421 gcaacacaag caaaactaaa tcgtggacgc cgtacagtag aaatcttgaa acaaaaattg
    12481 catgcaccgc tagctgttga aaaacaagta gtgattttgt atgctttgac acatggattc
    12541 ttagatagta tccctgtaga cagtatttta gacttcgaac atgaattatt cgaatatctg
    12601 gataccaatc attcagatat ctttgaaaca atccgtacaa caaaagatct tccagaagaa
    12661 gaagcgttga acagtgcgat tcaggaatat aaagacatgt tcttagctac aaaaggaaat
    12721 aattcctcta cagaagataa attgaaatcc attcaaaatg catagtgagg tgagatgaat
    12781 gggtgcttca ttaaatgaaa tcaagacacg tatcgcttca acgaaaaaaa cgagccaaat
    12841 cacgcgggca atgcagatgg tgtctgcttc taagttgaca aaatctgaag cttcttcaca
    12901 gaagtttcag gtttatgcaa caaaagtaag agaaatcgtt acgcatttga ctgctactca
    12961 gttaaatgat attgcctcag aaaatcctag aggggatatc aattacaaca gcatgttgct
    13021 cagccgtcct gttaagaaaa cgggttatat cgtcatcact gcagatggcg gtttagtcgg
    13081 tggatataac agctcgatat tgaaacaaac gatgtctatt ttagaagaag accaccaatc
    13141 acccgatgat tacgtgatga tcgcaattgg cggaactggt gcagacttct ttaaagcacg
    13201 cggtatcaat ctagcatatg agctgcgcaa tctatctgat cagccaagct ttgatgaagt
    13261 ccgcaaaatc gtaaatatgg caacaactat gtaccaaaac gaagtattcg atgaattata
    13321 cgtatgttat aaccatcata tcaattcgct aactagtcag tttcgtgtag aaaaaatgct
    13381 gccaatctca gacttagatc cagaagaagc aactactttc gaacaagaat atatttttga
    13441 accttcaaaa gaagaaatct tgtctcagtt attgcctcag tatgctgaaa gtttgatcta
    13501 cggtgcgatc gttgacgcca aaacagcaga acatgctgct ggtatgacag caatgaaaac
    13561 agcaactgat aatgctgcta atatcattga tgagctgacg gtttcttaca accgtgcaag
    13621 acaaggggct attacccaag aaattaccga aattgttgcc ggagcttcgg cactagaata
    13681 gtattgagat tggaggaaaa aagatgagtt caggcaagat tgttcaagta atcggtcccg
    13741 ttgtcgacgt ggaattttct ttagaccaat ccttaccaga tatcaacaac gcattagttg
    13801 tttataaaaa tgacgaaaat aaatcaaaag ttgttcttga agcagcgtta gaattagggg
    13861 acggagtgat ccggaccatt gcgatggaat caacagatgg tttacaaaga ggaatggaag
    13921 tcattgatac aggcaaagca atctctgttc ctgtaggtaa agaaacatta ggtcgcgtat
    13981 tcaacgtact aggagatacg atcgatttag aaacaccttt cccagaagat gcggaaagaa
    14041 gcgaaattca taaaaaagca ccagcctttg acgaattaag tacaagtaca gaaattttgg
    14101 aaacagggat caaagttatc gatttgcttg ccccatattt aaaaggtggg aaagtcggac
    14161 tattcggtgg tgccggtgtt ggtaaaaccg tactgatcca agaactgatc cataatatcg
    14221 cccaagaaca tggtggtatt tctgtattta ccggtgtagg tgaacgtact cgtgaaggta
    14281 atgacttgta ttatgaaatg aaagattcag gagttatcga aaaaacagcc atggtgttcg
    14341 gacaaatgaa cgaaccacca ggtgcacgta tgcgtgttgc tttgactggt ttgacgattg
    14401 cggaatattt ccgtgatgta gaaggtcaag atgtactgtt gtttatcgac aacattttcc
    14461 gtttcactca agctggatct gaagtatcag ccttgttagg acggatgcct tctgcggttg
    14521 gttatcaacc aacattggca acagaaatgg gtcaattgca agaacgtatc acatctacga
    14581 aaaaaggttc gatcacatcg atccaagcaa tctatgtgcc agccgatgac tacactgacc
    14641 cggcgccggc aacagcattc gcccatttgg atgcgacaac caacttggaa cgtaaattaa
    14701 cagaacaagg gatttatcca gcggtagatc cattggcttc ttcttcaagt gctttagcac
    14761 ctgaaatcgt gggagaagaa cattataaag tagcaacaga agtccaacac gtattgcaac
    14821 gatatcgtga attacaagat atcattgcta tcttaggtat ggatgaatta tccgatcaag
    14881 aaaaagtgtt agtttctcgt gcccgcagag tccaattctt cttgtcacaa aactttaacg
    14941 tggctgaaca atttactggt cttccaggtt catatgtccc tgtagaagaa acagtgaaag
    15001 gattccgcga aatcttggaa ggcaaatacg atgatcttcc tgaagaagct ttccgaagtg
    15061 ttggccgaat cgaagacgtc gtagaaaaag cgaaaacact aggctactag aaaggggtgc
    15121 cccatggatc aatatttaac agtaaatgtg gtaactcctg ccggtttggt ctatgatcac
    15181 catgcagcta tcgtcgttgc acgtacgaca gctggtgagc ttgggatttt gcctaaacat
    15241 gcaccaatca tcgttccatt gacgattgat gaagttcgtg taaaacgaac agattcagat
    15301 acccacgtcg attggatcgc tgttaatggc ggaatcatgg aagttcgtga taatgttgtt
    15361 tcaatcgttg ctgatagtgc ggaacgtgaa cgtgatatcg atgtatctcg tgcggaacgt
    15421 gcaaaacaac gcgcagaacg ccaaatcgaa gaagcaaaag caaaacaaga tacgaacgaa
    15481 ttgaaacggg caactgttgc gttgcaccga gcaatcaatc gtatcaaagt atctaagcac
    15541 tcataaaatg agatgcggat gtttatccgt gtttaagaac agtaaaaaga ggttatgaca
    15601 gaagtggtca gcttcaagac ataagaagga atttacgaaa attgcttctc aaatttttgt
    15661 gaaatctcag cttatttttc gaagaagcta cttctggaac accgtatatc ggaggttgtg
    15721 aaatcagcgt tttgtcctga gtattagaga aacaaatgga aaatagttcc tcatattttg
    15781 ccgttttttg agctaatacc gagggtcaga tgattgaaca ccgtttattt ggaataaggg
    15841 actgcgacaa
//
LOCUS       DAFEIE010000060        15554 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFEIE010000060
VERSION     DAFEIE010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.062"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(330..632)
                     /locus_tag="LP345_002140"
     CDS             complement(330..632)
                     /locus_tag="LP345_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760911.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(852..1218)
                     /gene="ssrA"
                     /locus_tag="LP345_002141"
     tmRNA           complement(852..1218)
                     /gene="ssrA"
                     /locus_tag="LP345_002141"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1389..2162)
                     /locus_tag="LP345_002142"
     CDS             complement(1389..2162)
                     /locus_tag="LP345_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1760912.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2306..2656
                     /locus_tag="LP345_002143"
     CDS             2306..2656
                     /locus_tag="LP345_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL1760913.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2637..3353
                     /locus_tag="LP345_002144"
     CDS             2637..3353
                     /locus_tag="LP345_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1760914.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3353..4801
                     /locus_tag="LP345_002145"
     CDS             3353..4801
                     /locus_tag="LP345_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1760915.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4871..5380)
                     /locus_tag="LP345_002146"
     CDS             complement(4871..5380)
                     /locus_tag="LP345_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760916.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5370..6095)
                     /locus_tag="LP345_002147"
     CDS             complement(5370..6095)
                     /locus_tag="LP345_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760917.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(6318..8438)
                     /locus_tag="LP345_002148"
     CDS             complement(6318..8438)
                     /locus_tag="LP345_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL1760918.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8668..9846
                     /locus_tag="LP345_002149"
     CDS             8668..9846
                     /locus_tag="LP345_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBL1760919.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9862..10620
                     /gene="aroD"
                     /locus_tag="LP345_002150"
     CDS             9862..10620
                     /gene="aroD"
                     /locus_tag="LP345_002150"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBL1760920.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10643..11128
                     /gene="ybaK"
                     /locus_tag="LP345_002151"
     CDS             10643..11128
                     /gene="ybaK"
                     /locus_tag="LP345_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBL1760921.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11199..12452)
                     /locus_tag="LP345_002152"
     CDS             complement(11199..12452)
                     /locus_tag="LP345_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1760922.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12569..13918
                     /gene="gdhA"
                     /locus_tag="LP345_002153"
     CDS             12569..13918
                     /gene="gdhA"
                     /locus_tag="LP345_002153"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBL1760923.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            14030..15376
                     /locus_tag="LP345_002154"
     CDS             14030..15376
                     /locus_tag="LP345_002154"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBL1760924.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
BASE COUNT         5140 a         2754 c         3134 g         4526 t
ORIGIN      
        1 aaagacattt gggttatatt gtgagataat aataaagaag agtttaaagc gttccccaaa
       61 aaccacttcc ccataagtgt gttacgcttt aaactctttt atatttgaag ccattaaaaa
      121 gcataccata taactgtaaa aaataatggg aaaaagactt ataattggag tggtagttaa
      181 ttagtgactt atttttgatt ttatagcact gatactataa aatatagata tcatcatatt
      241 acacaatctt aatactaact taaaaaatat cccttttata agtatggtga taaaatccgt
      301 tccgggctac cttttttagg tagcctactt taatctttat acctttctgg atcaacgaaa
      361 gtatacttca aatagtcata acgccgatga tcgctccgtg cgtctggcac atcagtcacg
      421 atatcaaaca aaaaatacac atctttcttc attctggttt ttgttgccgg aattttaaag
      481 tagttcttat tagagtaata gagattgatt aataagctat cttcgattgc taaaaagaaa
      541 acttctgaat cccacacctt ataaaaatct ttgacaaatc tattcgaagg atcaaattta
      601 aaccataatt gtgtttttcc ttccatcaac ataatgttca cctcaaaaag agtatacgaa
      661 ctaatgttct ttttgtaaag taggaatatc attgataata tggatggaac atatatatta
      721 aaaagtgttc tttttgaatg ctattttgaa tgccattttc attcatttaa cgaaaatctg
      781 cgaaaataaa aaatgctcaa acccttataa aataaggatt taagcatcta gcgaaatctg
      841 ctgaaatctc acaatggaga cggcgggagt cgaacccgcg tccaaacaca tcgccactta
      901 aaaatctacg ttcatagtca actcatttaa ggattcactt tacagcttgc cgagtgacag
      961 gcattctgta tcgctagtct gatgttctct ttttcaactt acagacggaa agttgaaacg
     1021 tatcccacta aagttaggac ccttactcga gcacatgggc gatgccgaga ggatctacgc
     1081 taactgtttt taggcagcta aagcgtaaga gttgttttcg tttttagcag ttatatttaa
     1141 ctgtaacgtt tttacgtaga cgtaacctac gaaacgcaat tcaagctcga ctgtgcctgt
     1201 cgaatccgta acgtccccgt tagctaacaa gggttacgtg tatttttcat acaaaattag
     1261 tatagcatat attgggataa attcaataaa aaagcgaatc atatcccatt atttatataa
     1321 taactgcccc tttcttaaga aaaaataagc gattttctta agaaaagagg tagcttcaaa
     1381 aaaagatctt aaatcagatc aaaatacttc aatgcgtgga caattccgcc ttctgtattt
     1441 ttctttgtga taaaggtaga aagttctttt aatccgtcat aggcgttgcc catagcgatt
     1501 ttgttgtcgc aagcttccaa caaggcaaaa tcattcggac catcgccaaa tccaaaagta
     1561 ggaacttttt ccagctgaag ttctttttgc agacgtttga cacctgcccc ttttgagatt
     1621 cctttcttca ctgtatcgat cgagtaagga ccattccgat aaaaagttag ctcaggaaaa
     1681 tgttcgtgat agtattcgtc acctgattga gataagatca gcaacatatt tactgtgttt
     1741 tctttaaagc ctaaaggatc aatttccgga acatctgaat gaatgaagtc gtaagcattg
     1801 atcattgttt ggctatgacc ggtacaccag attttctgat cgttatagta agaaagttca
     1861 tgaccgttca actgtacatg atcatacatt ttttgacatt cttctgaaga aaatgtttga
     1921 gaatagattt cttcgccgtc tactcgaatg aaagaaccat tcatggtgac cgcagaagta
     1981 atgcccgcat cttccatgat agagtggatt tctgcttctg tacgtcctgt agcgatgacg
     2041 gggagaacat tgttttcttt taatgcgttc atagcttttg ccacttcggg tgtgattttt
     2101 gatttcgcat ctagtaatgt tccatcaaga tcaaagaaag tgattgcacg ataatttgac
     2161 acaaataaaa ctcctttttt attggaataa gtttatctta acaaagaatg aacaaaagac
     2221 aaacctttcg tgaagaattc ctgaacatat tggttcagtc aacaatttag agtatactat
     2281 aagaagagaa tttaggaggg aaagaatgat ttttttcagt attggtatct tattcttaat
     2341 aattggcagt ctttttcgga ttctgccctc aaaaggaaat ctgccttttt atgggtatca
     2401 ttcgcctctt gccgcaaaaa cagacgctca ttggcggctg gctcaaaaga caagcggaaa
     2461 ctggtttttt cttatgggct tactgatggc attgatcggc tattatttaa agacatctgg
     2521 gcatacgaat tattttctga ttgaaatgct tctgctagta tttccaatta tgcctatttt
     2581 tattatgaca gaaaagaaat tacagaaata tgacctggaa actggaggga acgataatga
     2641 atattttaat gattgaagat aatcaatctg tttctgaaat gatgcagatg tttttcttaa
     2701 atgaaggttg ggaagcaact ttcaagtatg atggaaaaga agggctcgat gcctttttag
     2761 aaaacccaca acattgggat atgattacac tagacctgaa tttgcccaca ctggacggta
     2821 tgctagtagg aagagagatc cgcaaagttt caagtactgt gccgattatc atgctgacag
     2881 ctagagattc tgaaagcgat caggtgatcg gcttagagat gggggcagat gattatgtca
     2941 caaaaccttt cagtcctctg acgcttattg ctcgaatgaa agctttgcat cgccgtagtg
     3001 agttggcaga agcaagagaa gaagcagtag tttcagatga tcattttgat atcgagacta
     3061 gtcatttcaa gatgaatacg aaaacacgag aagcgtatct ggacaaccgg ccaattgaag
     3121 gactgacgcc taaagagttc gatctattgt ttactttagc aaaaaaacca cgtcaagtat
     3181 tctctcggga gcagttgctt gaattagtct gggattatca gtactttggt gatgaacgga
     3241 cagtggacgc ccatatcaag aaattacgac aaaaaatcga aaaggtcgga ccacaagtca
     3301 tccaaactgt ttggggagtc ggctacaaat tcgatgattc tggtgttgcc taatgcgtta
     3361 tttgtatcag caactcttag ctttctgcgg aatggtcgcg ttgatcttat tgatcgttgg
     3421 agtttctttt acacaactga caaaacaaac gattgaagaa aacaattacc agcaactgtt
     3481 tggatatgct gaatcagttg aaaagacaac gcaaacctat gccgatacgc tcccgcagtt
     3541 tagtcaagat caggcgtttc aaaatgcatt gctgctgaca gagcaagtac tgacagaaca
     3601 aaatgtgaac tttatattta tcgataaaaa cgaacgtgtc atttatccga ctaatacagc
     3661 tttactgaat tttaccttaa cagctgatca atggaaaaat ctgaggaatg gacgtcaaga
     3721 aaaattcaca tcgaataaaa atattttagg acaagcacag gcgacctctt acgcacttgt
     3781 gccatttaat ttgaatcatg aattctatgg agcacttgta gttagtcaac ctgcgcgaaa
     3841 tatcgataac agcgttcgtc caattacact gaacctgttc aaaggattta ttttttccag
     3901 tatcgttgca gttattgcca gctatgcttt tgcagcattc caagttaagc gtatcaatcg
     3961 gttaaggaat gcgacgaaag aagtgacgaa tggtaatttt gatgtacagc tccccgtaca
     4021 tgacaaagat gaatttgatg agttagcaga tgatttcaat aaaatgacga attcattgaa
     4081 agaatctcaa gcagaaattg aagaacaaga aaatcgtcga agacaattta tggcagatgc
     4141 ttctcacgag atgagaacac ctcttacgac aatcaacgga cttctggaag ggttagaata
     4201 caatgcaatc cctgaaaatc agcgagaaaa cgcgattaaa ttgatgaaaa atgaaacaga
     4261 gcgtctgatc cgtttggtga atgaaaactt ggattatgaa aaaatccgta cgaatcaaat
     4321 cagtatggtc attaaaaaat tcaatggaac agaaacattg aaaaatattg ttgcacagtt
     4381 agaagctaaa gcagaagcag caggagatac attgacattg aaagccgttg atgatattga
     4441 tgtttacgct gattatgacc gatttgtcca aatcatggtc aatattattc aaaacgcgat
     4501 acagtttact gaaaacggcc aaatcacgat tactttagaa aaaggctatc ttgaaacgat
     4561 catcacgatt gaagatacgg gaattggaat gtctgaacaa caaatgaaaa gtatctggga
     4621 tcgttattat aaagtagatc cttcaagaaa aaatacaaaa tatggtgaat caggattagg
     4681 tttaccaatc gtgcagcaac ttgtacgctt gcataaagga aaattagaag tagaaagcga
     4741 actaggaaaa ggaacaaaat tcgctgttcg tttgcctgac gtagaaatca aaaaagagta
     4801 aaaaacaagc ggtataaaag atcatgaatc gatcttctat accgcttgtt tttactataa
     4861 aatgattgat ttagcccgcg ggctctaaac gatcaatata aggactttga gcaatagtag
     4921 catcatgagt aaagagtaag ataccttgat tttcttcatg agctaaataa gaaagcaagt
     4981 ggagtagctc ttggatctcc aatacactaa gttcatcaaa tgtatcttca ataacaatat
     5041 tgtttcgctt ggaaagcaag gcatgaagta attgcagctt tactttttca aaagacgtca
     5101 actcagctgc cgcacaatta agcaaggaag gagagatatc aagtttttct tgataggcca
     5161 aacgatcttg tttgatttct ttttccggta catccaacag gacatggtct ttaagattca
     5221 gataaggaaa catcggccaa tttttttgga tgatcgcaaa attatccagt tttgcaacaa
     5281 gaacctcttt tttcaagtgc tccaatattt tatgctgttt ttcgagagga cacaaaataa
     5341 cggtcaagtg ttcagcatga atcaaatatt caggtttcat tacgtccagg cctcctactt
     5401 tgcaaatgat ggataaaaaa agtgaaaggg aatagactaa gaatgagaca gcatccactg
     5461 agcccaataa gagtttgggc aaatccctta agtatatctg tgaaaaaaag atcattttgg
     5521 aaatcgatgg taaaaaaagt ctgttgatcc atcggaattg taagtccgct taccgaagtc
     5581 aagatatcac ggatatctgg cagttcagta gtctttaaga caagaaaatt gatcctttga
     5641 agaagcgctt cataaactga ctggaagctt acgatccaca ataaaaccaa gatacaacaa
     5701 agaaagagag gaaagaacag ctgccagaaa ataaaaagga ataatttggt tttagaaaga
     5761 ccagtcaggt gccaattgat caattcctgc ttgttttgcc tgactgaata gtaaaagaaa
     5821 aagataaaaa ggaaggcaaa tagaaaaaat aaactgaata tgccttttat ataaaatcgg
     5881 ctagctaatt ctaaagccgg aagaagctct gtagatgcag aagcgccaat aaatgaaagc
     5941 cgatcttgga cttgattggc taaagccgat tgcaaatggt aaagagtcag gcatgctatc
     6001 aataaaaaag cagaaaagct tgaaaataaa caatagagta ttgtctgctt tttgtaataa
     6061 attaatcgag cagtagcata gcggattatt ttcatacttt tcacctctat aaaaagtata
     6121 gaaaatgaat atgaataaag tatgaaattc ctttagtgaa atcacgaatt aaaaccagaa
     6181 aatattttgt aaaaagcaag aggttgtgaa gaagctgccc tattctatta ccgtagatgc
     6241 aagcttttga acactgttta ttcgaaaaga ggagcagcga caataatttt gtcgctgctc
     6301 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
     6361 gtttgcgttt tataaagatc aacagttgat tgtccgttgt gttcactaaa gacactagtt
     6421 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
     6481 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
     6541 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
     6601 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
     6661 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
     6721 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
     6781 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
     6841 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
     6901 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
     6961 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
     7021 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
     7081 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
     7141 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
     7201 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     7261 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     7321 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     7381 ctaatgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     7441 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     7501 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     7561 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt catgctggag accattctca
     7621 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     7681 ttttttcctc tagcgagccc gaacaaatcg tcatttggtg ctgcataatg ttcttttaca
     7741 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     7801 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     7861 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     7921 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     7981 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     8041 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     8101 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     8161 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     8221 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     8281 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     8341 aaataggcaa aaatcgtttt caaccaaagt aaaacgacta gtaaagaaaa aaatccgagc
     8401 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     8461 cttaatcaca gaagtgtcct gaaaccatgt tacacagctc acttattctc atttatttta
     8521 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     8581 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     8641 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     8701 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     8761 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     8821 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     8881 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     8941 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     9001 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     9061 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcatagg aggctatgag
     9121 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     9181 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     9241 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     9301 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     9361 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     9421 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     9481 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     9541 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     9601 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     9661 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     9721 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     9781 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     9841 cattagaagg agcgatgcag aatggttcgg gtaaagggat tgaatatagg aagcggtaga
     9901 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     9961 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
    10021 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
    10081 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
    10141 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
    10201 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
    10261 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
    10321 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
    10381 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
    10441 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggttggc
    10501 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
    10561 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
    10621 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
    10681 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
    10741 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcgta tatttaaaac
    10801 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
    10861 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
    10921 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
    10981 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
    11041 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
    11101 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
    11161 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
    11221 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
    11281 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
    11341 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
    11401 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
    11461 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
    11521 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
    11581 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
    11641 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
    11701 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
    11761 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
    11821 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
    11881 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
    11941 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
    12001 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
    12061 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
    12121 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
    12181 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
    12241 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
    12301 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
    12361 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
    12421 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
    12481 tctgaagaaa gaaaacagaa aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
    12541 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
    12601 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
    12661 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
    12721 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
    12781 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
    12841 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
    12901 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
    12961 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
    13021 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
    13081 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
    13141 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
    13201 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
    13261 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
    13321 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
    13381 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
    13441 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
    13501 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
    13561 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
    13621 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
    13681 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgtccagcg
    13741 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
    13801 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
    13861 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
    13921 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
    13981 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
    14041 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
    14101 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
    14161 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
    14221 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
    14281 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
    14341 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
    14401 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
    14461 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
    14521 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
    14581 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
    14641 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
    14701 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
    14761 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
    14821 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
    14881 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
    14941 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
    15001 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
    15061 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
    15121 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
    15181 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
    15241 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
    15301 caagaaaaac atgttcgcac ttctaggcaa accaggcttt gaagatcttg ctaaagaatt
    15361 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
    15421 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
    15481 ttcagaataa ggggctgtga caagacgttt gtcaggctct ttgtcaaatg atgttggtaa
    15541 agagaaatct taga
//
LOCUS       DAFEIE010000061        15234 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFEIE010000061
VERSION     DAFEIE010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.063"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..803)
                     /locus_tag="LP345_002155"
     CDS             complement(<1..803)
                     /locus_tag="LP345_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1760925.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTS"
     gene            1076..3547
                     /locus_tag="LP345_002156"
     CDS             1076..3547
                     /locus_tag="LP345_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1760926.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3650..5386)
                     /locus_tag="LP345_002157"
     CDS             complement(3650..5386)
                     /locus_tag="LP345_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBL1760927.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5383..6087)
                     /locus_tag="LP345_002158"
     CDS             complement(5383..6087)
                     /locus_tag="LP345_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1760928.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            6218..6721
                     /locus_tag="LP345_002159"
     CDS             6218..6721
                     /locus_tag="LP345_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBL1760929.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6681..7019
                     /locus_tag="LP345_002160"
     CDS             6681..7019
                     /locus_tag="LP345_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBL1760930.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            7040..8458
                     /gene="ffh"
                     /locus_tag="LP345_002161"
     CDS             7040..8458
                     /gene="ffh"
                     /locus_tag="LP345_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBL1760931.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8570..9148
                     /locus_tag="LP345_002162"
     CDS             8570..9148
                     /locus_tag="LP345_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBL1760932.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            9152..9673
                     /locus_tag="LP345_002163"
     CDS             9152..9673
                     /locus_tag="LP345_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1760933.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9752..10324)
                     /locus_tag="LP345_002164"
     CDS             complement(9752..10324)
                     /locus_tag="LP345_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL1760934.1"
                     /translation="MKEEKSYDKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFV
                     KIDDLPFYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGS
                     RPYGHSVWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLI
                     DENGNIVEGTLSFFQTILDAYLDFSNKLTE"
     gene            10558..10833
                     /gene="rpsP"
                     /locus_tag="LP345_002165"
     CDS             10558..10833
                     /gene="rpsP"
                     /locus_tag="LP345_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBL1760935.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10845..11096
                     /locus_tag="LP345_002166"
     CDS             10845..11096
                     /locus_tag="LP345_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBL1760936.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            11221..12012
                     /locus_tag="LP345_002167"
     CDS             11221..12012
                     /locus_tag="LP345_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760937.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            12182..12703
                     /gene="rimM"
                     /locus_tag="LP345_002168"
     CDS             12182..12703
                     /gene="rimM"
                     /locus_tag="LP345_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBL1760938.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12693..13454
                     /gene="trmD"
                     /locus_tag="LP345_002169"
     CDS             12693..13454
                     /gene="trmD"
                     /locus_tag="LP345_002169"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBL1760939.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13590..13937
                     /gene="rplS"
                     /locus_tag="LP345_002170"
     CDS             13590..13937
                     /gene="rplS"
                     /locus_tag="LP345_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBL1760940.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            14195..14488
                     /locus_tag="LP345_002171"
     CDS             14195..14488
                     /locus_tag="LP345_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBL1760941.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         5074 a         2749 c         3093 g         4318 t
ORIGIN      
        1 tgtgaggttc gaaaacgatt catgatctgg acacgtaatt gattgaagct gcgattgatg
       61 tgttggacaa tatgaaagcg gtcagttacg atctccgcat ttggaaagac tgttttaagc
      121 aactgacaat agctggcatt catgtccatc actaggtact tgacctttaa acgggccttt
      181 ctaggaaagc gcaggaagta ttgagttagt ttgtaaagtc tgcgatcttc aaggatcgta
      241 aatagctgat tggttgtccc atcaacacaa ataaaactca tggaaccaga aacagaattc
      301 attgatttga actcatccat acacaacacc gtcggaagga agttcatacg tggctggtaa
      361 tgcttcgttg cttcacgcaa gatccgtgtc accgtcccat ccgagacgaa gtacttctta
      421 gcgattagtt tacgtgattg attttcgtac agttccatga gaatcgcctg cttcagttcc
      481 tttgttagtt gatgatgttc atcaactaag tccgttttcg cagaaaaggt ccttccacaa
      541 tcatggcaga gaaaacgggt acgttttaat tctaaaatag ttaacttttc tttgactttc
      601 aacatctgag tgcgtgtcgt ataggaaccg ttgcggataa tacgaaccga tcgacagtgt
      661 tcacaatagg aagaagagtc atccaatttt cctttaataa actgcgcttg aacgccttta
      721 tattcttttt caatcagcca ttcttcatca aaaaataaat gtttatctgt taatccgagt
      781 aattttctag tatgattatc cattgagaga ctcctttggt aggatgacgt tttggtcgac
      841 taaattttac caaaagtgag tctctttttg agttgaaacg aagaaaaagt gttagtagaa
      901 aatcgccttc gattttccac caacacaaaa tattatagaa cccttttttt ttgctatatg
      961 acaggaatga aaggtgtttg caagcttaat gtgaggaaca ctttccatat ctgttctata
     1021 ctggatagga gaagtttgga aatatccaga aaacgaaatc aatcgaggta gccacatgaa
     1081 gaataaatgg ataaatcgaa gtaaaaaaaa gaaagtaaca caaagatcat cagataaagt
     1141 catccgtctt tttccatcgt ataaagaagg attaacggca gatcaagtca aggaacgaat
     1201 agaaaaaggt gcagcaaata attcagtcga tcccacattc aaaacaaatc agcaaatcgt
     1261 attggaaaac atatttacgt atttcaattt gatctttctt atcttagcca ttttgctttg
     1321 tttagtagaa tcctataaga acttgacttt tttaccagtt atcatagcca atacaggaat
     1381 cgccattttt caggaaattc gatccaaaaa gatcttggac gaactaaatg ttttaaatac
     1441 agcaaaagtc aatgtcatac gagacgggat agaacaaaca atagatatag aagaccttgt
     1501 aatagatgac attgttattt tagagactgg atatcaaatt ccagcagatg cagaggtcgt
     1561 ggaagggaaa ctgcaagtta atgaggcttt attgacaggc gaagcagatg aaataaccaa
     1621 agaaataggt gatccattaa tgtccggcag tttcattgtt tccggaaaag cttacgcccg
     1681 attagacaaa gttggagcag attcgtatat ttcccagctg acagtcaaag ccaagacaat
     1741 gggagaagga gaacagtcgg agatgattgc ttctcttaat caattgatca aatggattgg
     1801 gatcatcatt attcctatcg gtatcctgct tttttctcaa agttactttt ttaatggaaa
     1861 cacgatcaaa gaaagtgtcg ttgcaatgga agcagcattg atcggtatga tacctgaagg
     1921 actgtacttg ctgacgacga ttgcattagc attaagtgcg actaaactag caaagcaaag
     1981 agttctttta cacaatatga aaagcattga gacattggca agggtaaatg tcctttgtgt
     2041 agataaaaca ggaacgatca cagaaaataa aatgtctgtt caaaaaatga tcgtctctaa
     2101 aaaacaagaa ataatcagtc agtcagatca attggaagca tgcattgctg actatgcaaa
     2161 agcgatggca ggagacaatg caacaatgga agctgttaaa gcatatttta caaaaaccac
     2221 tgatcaatcc tatcaccatg ttattccttt ttcttctgtc caaaaattca gcagtgtagc
     2281 gttggcagac aaggtgtatg ttttaggagc gcccgaaatg gttttgcgcg atcaattgcc
     2341 ggaatatgcg gaagagtttg tttctttcgc tgaaaaaggc tatcgcgtgt tggtctttgg
     2401 tgtgtacgat gggattcttg aagaaccagt attgacagaa gcagtcacac cattaggcta
     2461 tattctgatt gctaatccta tcagaaaaga agcaagagcc acatttgatt acttcaaaaa
     2521 acagcaagta gccatcaaag tgatttctgg agataatccg ctcaccgtat ccaatgtagc
     2581 tgtccaagca gggatttcac atgctgatca gtacgttgat gcatctaaat tatcagaaga
     2641 agaatatgaa gcagctgtcg aaaaatatac agtttttgga cgcgtcaagc cagaacaaaa
     2701 gaaaatcttc gttcaattga taaagcgtaa caatacagta gctatgacag gtgatggcgt
     2761 gaatgatatt ctagccatga aagaagcaga ctgcagtata gcgatggctt ccggaaatga
     2821 agccgccatg caggcctcac aagtggtctt acttgattct gacttttcac gcatgccaga
     2881 agttgttgca gaaggacggc gcgttgtgaa caatattgag cgatcagcca gcttgttttt
     2941 agtgaagaat attttctcct ttttgctctc actgttttca gtgatctttg ctctgaccta
     3001 tcctttagaa ccatcacaaa tcacattgat tagtttgttt actatcggac ttccatcttt
     3061 cttgcttgct ctagaagaaa acaaaaagcg aatcagaggg aaattcatca tgaatgtgat
     3121 ggaaaaagct gtgccaggtg gactaacaga tatgatcgta gtcggtgcgt tggtgatctg
     3181 cggggtgact ttgaatctaa ataaaacaga tgtttctaca gcatctacca tgcttttgat
     3241 tgcagtaggg ttcctcgttc tctataaaat ctgttcaccg ctgaataaat tcagaagtca
     3301 gatcattctt ttctgtgcta gcggtaactt tttttcggtc atctttttgc ataagctgtt
     3361 ttcaatcacc ggtatctcag ctgtatcact tttgctgttg agcattctat ttttctcggc
     3421 agattcgatt tttaggcatt tgaccacatt ggtagaatat ttgtttgaac gtaaaaatga
     3481 aaaagagcaa aagccgttta gtcgcgtagc taaaaaattt ctatcgatat ttaaacgaga
     3541 aaattgacga aaagtatctc aaaaaagagt aaaaaagaac aaccactcgt gtatctttcg
     3601 aagcaggatg agtcatccaa ctttaaaacg cacgagcagt tgctcttttt tacattttcg
     3661 gaatggtaac ggtgaaagtc gaacctgttc caagatgact gtctacagta atcgtaccat
     3721 taaggagttg cacgtagtct tttacaatcg ctaaccctaa tccggtcccg cctgaatgtc
     3781 ggcttcgcgc cttgtctacg cggtaaaaac gctcaaagat ccgttcctga tcctcaatgt
     3841 cgatacctat accaaagtct tggacagaaa acgatagatc atctgttgcc tgatagcgga
     3901 taataatctc gctgtcgctt tttgaatatt ggacagcatt ttcaatcaga tttttgataa
     3961 ttggataaag gatatctgtt ttagtagtaa atggttcgtt ctttccaatc aatcgaatcg
     4021 tcaaccgttt cttttcgatg attggctgat aattttgaac gatttgctgg aaataaggtt
     4081 ctgtataaat tgtctggatc tcgtaagaat tctcgccatc ttttgacagc tggatgattt
     4141 cccgaatcag tttatctaac cggatcgcat ctttttgcat gatctcaaga aaagaagtca
     4201 gagtttgcgg gtcatctttt gcaccatcca gtaaagtctc ggtaaaacca atcagtgaag
     4261 tcacaggagt ttttaattcg tgagagacgt tgccaacgaa atccttttgt agcttttcta
     4321 aacgtcgcac tttcgttaag tcatacgcca cccctagaat ctgtccggta ccttctgaat
     4381 tagtaaagta gcgcaaactc aagtctaatg tctgccgacc ttctgtaagg gtgatctcct
     4441 gatggatcag cggatgctca ggagtcactt gatgaatcag ctgaatgagt tttggctctt
     4501 gaatgacttc tgtgtaccgc tgttcaggtt gatagcttac cacgtttaaa tgtagctgca
     4561 tctttggatt aagcagtagt aaacgagaat cagcatcatc aatcaggaat acgccaatca
     4621 tcagttcgtt cagtaacgta tataattgct cttctgtggt agtacacgcc cgatacatct
     4681 tactcatttg ttcgctcaac gcattaatcg tctgatacaa ttcttcccat tgatcgggtg
     4741 tttgcatgat tacttccgcc tgattaggat tttgcaccat tttttttagt acgggcagca
     4801 cggttttcaa tggctggttt ttttgataga tcagataata gatcattcct gcaagaacaa
     4861 ggaagaaaga cagaaagaag aaaaagaccc aacggcgaaa actctcagtt ctcggtaaaa
     4921 aaacgcttgt cggttctgcg atacgtaaaa tggcttctaa ctggccactt tttttgactg
     4981 gtaatgcgac atataaaaga tcctcattca aagtagtact tttgcgcaaa gcgctaccta
     5041 ggttcccacc attcaatacg gctttgattt cgggacggga gtttcgctgt tcattcaatg
     5101 tttcattgtt tgtgtcaaat aagatctttc cagtagcatc cattaaagta atccgttcgt
     5161 tcgactgatg gacgaattct tccaaagcag ttttgttttg cgctgcttgg aggttttcga
     5221 catctaattg ccggatcagc agttgtgctt tttttgtcag gtagctttct tgctgttcca
     5281 cgatctgctg ttgaaaataa tgggaaatca attgccagcc accaaaaaac aaactaacta
     5341 aaagaataag aaagaagaga cgttcataaa tttttttcca tttcatcgtt tgggttcctg
     5401 aaacttatag ccaaatcctc taatagtcac caagtacttt gggtgttttg gatctcgctc
     5461 gattttttct cgcaaatgac taacgtgtac atctacgatt cggctttgtc ctgcgaagtc
     5521 aaaattccaa atgcggtcta gcaatgtgtc tcggtcgatc acacggtctt ttcgtttcat
     5581 gaaataaaca agtaattcaa attctttcgg tgttagttca atcagatggt cgtctacggt
     5641 cacttgataa ttggtcaaat cagcagtgat ttgtccaatc gatagatatt caggctcagc
     5701 ttcatctttt gattgcttac gaggttcaat tcgtctgaat attgctttca tacgggctaa
     5761 tacttcgcga ggactaaatg gtttggtcaa atagtcgtca gcacctattt ctaggccaat
     5821 gatccgatcc acttggtcat ctttagccgt cagcatcaaa atcggtgttt catttttttc
     5881 ttgacgcagc cgctgagtga tctccatgcc atccatcgtt ggaagcataa catctaaaat
     5941 gatgaaatca aatgattgtt ctaatgctaa ttctaatcct tcgcctccat ctgtggcact
     6001 ggttaccttg tagccttctt tttccaaatt gaacgtcaag agcgttacaa tagaaggttc
     6061 atcatcaaca actagtattt ttttcattca aatctccttt aaataggttt cattctgttt
     6121 atattttagc atagaatcag tacaaagggc tattttacaa aagaaataaa tggtataata
     6181 ggaaggcact ttgctgaata gaaaggaaga gcagtcaatg attggaatca gtgcatgttt
     6241 aggcggtctg gcctgtcgct atgatggaca gaaaaaagaa gtaccagaat tgatggaact
     6301 agttgaaact ggagaagctg tcatggtctg tccagaagtg atcggcggat taccaattcc
     6361 tagagatccc gctgaaatca ttggtggaaa tggattcgat gtgtggaaag atcaagcaaa
     6421 agtatggacg acaagcggcg aagatgtaac ggaagcgtac aaaaatggcg cgatcaaagc
     6481 ctatcaaaaa ttgcaggaaa aacacattga tctagtcatc atgaaggaaa aaagcccttc
     6541 atgcggaacc cattcgattt atgacggaag tttttccgga ataaaaaaaa atggtgccgg
     6601 agtggctact gcttatttta ttcagcaaaa aatgactgtg ctctctgatg aagaatggct
     6661 gaaaactaga ggtgagcaga atggaaatcg aaaagaccaa tcgaatgaac gcgctctttg
     6721 aattttattc gaccttattg acagaaaaac aaatgaacta catggaatta tattatgcag
     6781 atgatttttc attaggtgag atcgcggaag aatacgaagt aagccgacaa gcagtatatg
     6841 acaatatcaa gcggacaagc aagatcttgg aggattatga aaaaaaactc catctttttt
     6901 ctaattatat tgttcgagaa caggtattgg aaaatatgac tgcatatatt acagataagt
     6961 acccggaaga taaaaaacta cttgaatatg tacagcaaat tcaagcaatc gaagaataaa
     7021 taaaaggaat gaagaaaata tggcatttga aagcttaact gaacgtctcc agcaggcgat
     7081 gggaaaaata agaaaaaaag gaaaagtatc agaagctgac gtaaaagaaa tgatgcggga
     7141 aatccgcctt gccttactag aagccgatgt taacttgcaa gtagtcaaag attttactaa
     7201 gcgcgtacgc gaacgtgcgg taggggcaga agtgctggaa agtttatcac ctgcacaaca
     7261 aatcgtaaaa atcgttgatg aagaattgac gatcacactt ggttctgaaa cagcagagtt
     7321 aaataaatca ccaaaaatac caactgttat catgatggct ggtcttcaag gggcaggtaa
     7381 aacgaccttt actggtaaat tagccaatta tttaaagaaa aatgaaaatg ctcgtccgct
     7441 cctaatcgca ggggacgtat atcgaccagc tgcgatcgac caattgaaag tattaggtca
     7501 acagctagac gttcctgtat ttgatatggg aactgaagtc agcccggtag agatcgtccg
     7561 tcaagggatg gagttagcaa aagaaaagaa aaacgactat gtattgatcg atacggcagg
     7621 acgtctgcat atcgatgaaa cattgatgga tgagttgaaa caaatcaaag aattgacgca
     7681 accaaatgag attttgcttg ttgtcgatgc catgactggt caagatgccg tcaacgtagc
     7741 tgatagcttc aaccagcaat taggtattac aggggtcgtc atcactaaac ttgatgggga
     7801 tactcgaggc ggggcagcac tatcgatccg ctcagtgaca ggcgcaccaa tcaaattcat
     7861 cggttctggt gaaaaattga ctgacttaga agtattccac ccagatcgta tggctagccg
     7921 tatccttggt atgggggata tgctgacatt gattgaaaaa gcgcagcaag actacgacga
     7981 gaaaaaagcg gaagaacttg cacagaaaat gcgggaaaat tcattcgatt tcaatgactt
     8041 tattgaacag cttgatcaag tgatgggtat gggcccactg gaagatctaa tcaaaatgat
     8101 cccaggaatg aatcaagtcc ctggaatcga aaacgtcaag gtagatccaa aagatgttga
     8161 acgcaaaaaa gcgatggttt attctatgac gccagcagaa agagcaaatc ctgatctgtt
     8221 gaacccaagc cgtcgtcgcc gaattgctgc cggttctgga aacagtgttg ttgaagtgaa
     8281 tcgaatgatc aaacaattca aggaatcaag aaaaatgatg cagcaaatgt ccaaagggga
     8341 tatgaacatc ccaggtatgg accaaatgtt tggttcaggc gtcaaaggaa aactaggcaa
     8401 aatggcgatg aatcgaatga tcaagaaaaa taagaagaaa aagaaaaaac ggaaataaga
     8461 tgaaaaaaac agcttcggta cagactgaaa atgtctactg ccggagcttt tctatcagca
     8521 atttttattc tttactaata caattactct aaacgaagag gtggcacaga tgagatgtcc
     8581 gtggagtgaa caaacagaaa gtatgcggca atatcatgat actgtctggg gtgttcctga
     8641 atatgatgac caaaagctgt tccgaaaatt gatgcttgat attaatcaag ccggattgag
     8701 ctggcagacg attttaaata aaagtgaagc attcgatgaa gcatatgatc gattcgatat
     8761 caaaaaagtc gcaaattatg gagaaacaaa aatcagtgaa ctaatggaaa acaaaggaat
     8821 tattcgtaac cgaagaaaaa tcgaagcagc cgtccaaaac gccaaagcag tcttgaaaat
     8881 tcaagaagaa atcggcagtt tttcagagta tctttggtcg ttttctaatg gaaaaatcgt
     8941 tgattcttct tatcattcac aagaagaagt cccaacaaca agtcctcttt cagatgaatt
     9001 agcaaaagat ctaaagaaaa gaggatttaa atttatcgga agcacaacaa tctatgcttt
     9061 tttagaagct gtcgggatca tcaatgatca ccttgacagt tgtttccgca aagaagaggt
     9121 cgtacgtatc ggcagaaagg gcgaataaag catgcgaaaa atcatatttt atggtgctat
     9181 aagtttagat ggctatttgg caacgaaaac ggatgatctt caatggcttt ttgacactcc
     9241 aacaggtaag caaactactt atgaagcttt ttatgaaaca atcgatacga ccatcatggg
     9301 cagaaaaact tatcaggaag caaaaaaata tttggagacc gaagcaattt atccagagaa
     9361 aaagaatttc gttttttcca cccacgcaca attacaattg ccagatgctg aggtcgtaaa
     9421 cgaagatcct gttgcttttc taaaaaatct acaaatgaca gaaggaaaag atatctgggt
     9481 tgtgggtggc ggtcgattga tcaaaccgct attggaacat caaatgattg atgaatggta
     9541 tatccagatt acccctgtat tattagggga cgggattcct ttattccaaa aaggaacata
     9601 tgaagcgcgt tttgaaatgc tagacacgac acgattcggt gaatttatcg aattgcatta
     9661 tgtacgaaag tagaagtaaa taaaataaaa aaggcaacta tatgcagaaa tgtcctgtac
     9721 atagttgcct tttttattac cgttatgctt tttactctgt taatttgtta gaaaaatcta
     9781 gatacgcatc taaaatcgtt tggaagaaac ttaatgttcc ttcaacgata ttaccatttt
     9841 catcaattag attcgcaacg tttccgatat atgcttccgg ttgctgcaag gttggcacat
     9901 tcaaaaagac aagtgattgg cgtagatggt ggtttgcgcc aaagccgccg atcccacctg
     9961 gtgatgcagt aacgactaaa cctggtttat gatcccaaac actgtgtcca taaggtcttg
    10021 agcctacatc taaagcattt ttcaatactg ctggcacaga acggttgtat tcaggagtaa
    10081 cgaaaacgac accgtctagt cccctcactt cctcacgaaa acgagtccat tcagcaggag
    10141 cctgttctgg agtttcgaga tcctcattgt aaaatggcag atcatcgatt tttacaaata
    10201 cactttcgta cccttcagga agcaatttcg caaaagcttc tgctactttt ttgttgtaag
    10261 aatcttttct taaactacca ataaaaaatc caattttttt gtcatacgat ttttcctcct
    10321 tcaaactatc tataataatc ttacaaaaga taagtaactg gagcaaataa aaacacttac
    10381 tgacaaaagc tacatagaag atagattact tatttttaac aaaaaagaag tctaaaatct
    10441 tctattttct aaaaaaaatc gaatttaatc aagctgtaaa gaaaaaaagc tttacagggt
    10501 aaaaaaaaac tgttacacta catcttgtga ataaaacaat ggaggtggaa ataaataatg
    10561 gcagttaaaa tccgtttaaa acgtatgggt tctaaaaaga gtccgtttta ccgtatcgtc
    10621 gtagctgatt cacgttctcc tcgtgatgga cgtttcatcg aaactgtagg tacttacaat
    10681 cctttgaaag accctgcaga agtagtttta aaagaagact tagttcttga ctggttatca
    10741 aaaggtgcac aaccttctga cactgtacgt aacatccttt caaaagaagg cgttatgcaa
    10801 aaacaccacg aagctaaatt ctcaaagaaa taaggtgacc ggatatgaaa gatttaagcg
    10861 acttagtctt aacaatcgtt cgtccgctag tcacttatcc tgatcaagtc aagttagacg
    10921 tcgtagagtc gaaagacttt tacgagtaca atctaacagt ggctcctgaa gatattggcc
    10981 gtatcattgg aaaacaaggg cgtgttgcta aagcaatccg cacaatcgtt tacggtgttc
    11041 ggatcaatgc accgaaaaaa gtgcgtttga atatcatcga tgataaggaa aagtaaataa
    11101 acgtgctgta ctcgaatttt cgagtgcagc ttttttgttt tttttattaa ttgaagaaat
    11161 gattatttgg caaaacaagc aagaaagcgt atccttatag gaggagggag tgaacagcca
    11221 atgagaaaga aaatgttatt tattccattt gctctattgt taagcgcttg tagttcggtt
    11281 actcaagaat cagacaatac acatctatca agcagtatat ctgaaactgt taccagtcca
    11341 gaaaaaagta gtaccaaaac ggcttccacc actgaacaaa caatggctac ctcaaataat
    11401 gagaaaaaga ctgctttaga ccagttgaaa gaacaacagc caaatgttcc catgcctcta
    11461 gatgtaccag tctcttcagg ctatctcaat atcgcagcga cacatacaaa gcaaggttat
    11521 tctattttat attacagaac agatcgtccc ctcgggttga atgctgacga attgaatcaa
    11581 gaaacgccta ttgcaaccta tctatatcaa tatgggtttg cttctagtca agaaacaatc
    11641 caagttttgc agccatttga gatcgacaca aatggtcagc aagtggactt aggttctcga
    11701 atcacagggt atcagcaagg tgcagcaggt tcaagttttc ttgaatggca agaaggaaac
    11761 tggcgtattc gaatccgtgg gaataatata gaaggccaag atcccttact attagctaaa
    11821 gaaatcgtag cttatttgga agaaaacagt ctaccagcac ctgaacaatt tggtaaaatt
    11881 actgttgata tgggtgatac gacgaatcga gccgtagaag taagctggca agaaccgaaa
    11941 aatgcctata cgatcactca tcaagatcct atgtctgcgt tgaagatggc agtttctatg
    12001 aagaggttgt gaaatcagcg cgctgatctg agcccatcat ttaactccaa gtcacaggaa
    12061 gtaatcaaaa atagcacgcc gcatttttgc ataattttgg cttaatacct taaaagaaaa
    12121 ctagaattgc ctcttcacac atgctaaaat aaaacagaca aaaaagaaat ggggatataa
    12181 gttgactgaa tacttgaatg taggaaaaat cgtaaacaca caaggtatca aaggcgaagt
    12241 ccgtgttatc tcaacaacgg atttcccaga agaacgttac aaaaaaggaa cggtgctaac
    12301 actattccaa gacggaaaag cacctgtgga attaacagtc aaaagtcatc gcaaacataa
    12361 aaattttgac ttattgagtt ttgaaggaca tccttctatc aatgatgtgg aaaaatatcg
    12421 ggatggcata ttaaaagtgt caaaagacaa ctctgtagat ctagctgaaa atgaattcta
    12481 ttaccatgag atcatcggtc tgcatgtatt agaagatgga actgagttag gtaaagtaaa
    12541 agaaatcttg tcaccaggtg ccaatgatgt ttgggtcgtt caacgtccga aaaaagctga
    12601 tatattgctt ccatatatcg cttctgtcgt caaagaagtc gatttagaag ctggagtggt
    12661 ccgtgtagaa attccagaag gactgattga cgatgaagat tgatgtattg actttatttc
    12721 caagaatgtt tgaaggtcct atgggggaat ccatcatcgg taaggctgta gataaaggat
    12781 tattagatat caatatctct aacttccgcg attattcaga taacaaacat cagacagtag
    12841 atgattatcc atacggcggt ggagcaggta tgctgctcaa agtccagccc atctatgata
    12901 acatccaagc cattgaaaaa gctgcaccgg atgtcaaaaa aagagtaatt cttcttgacc
    12961 cagctggtaa acgattcgat cagaaaatgg cagaagaatt ttcacaagaa gaacacttag
    13021 tattcatttg tggtcattat gagggatatg atgaacgtat ccgcacatta gtgacagatg
    13081 aagtttcctt aggagattat gtccttactg ggggagaatt aggtgcgatg gtcatgatcg
    13141 atgcaacagt tcggcttttg ccagatgtgt tagggaatca gacttcagct caaacggatt
    13201 cttattcaac cggtttattg gaacatcccc aatatactcg cccggcagaa tataaaggga
    13261 tgaaagtacc agaagtattg acaaatggaa atcataaatt gattgaagaa tggcaattaa
    13321 aagaatcact aagaaggacc tatcaacgtc ggcctgatct tttggaaaca cttgaatgga
    13381 cacctcaaat gacgaaattt ttagaagaaa tcaagaaaga agaacaagaa aaaacagcag
    13441 atgaagccaa gtgacttttt ctaaaatctt ctttacagta ggttgataat atgttagtat
    13501 tttatggtga gtgcaaaagc acttaactat tacgatattc cgctgtgaga aaagctcata
    13561 agaatatttg gaataaggag aagaaaacca tgaatccatt aatcgaagaa ttaacaaaag
    13621 aacaattacg ttctgacatc ccagcgttcc gccctggtga cactgtgcgt gttcacgcaa
    13681 aagttgttga aggtactcgt gaacgtatcc agttatttga aggtgttgtt atcaaacgcc
    13741 gcggtgctgg aatcagcgaa acttatacag tacgtaaagt ttctaacgga gtgggcgttg
    13801 aacgtacatt cccattgcat acaccacgtg ttgcaaaaat cgaagtagtt cgctacggta
    13861 aagtacgtcg tgcaaaattg tactacctac gtgcattaca cggaaaagct gctcgtatca
    13921 aagaaatccg tcgttaatca ttgttatcag actgagaaag aacccttggt attcaagggt
    13981 tcttttttct tagcatgtaa tttgaacacc ctgatccagt tttttcttta attattggta
    14041 ggggagaata atggattaga ataaatctac ctataagtag tagtaaaaaa aagagcacta
    14101 tgataatatc tttcttaaga gtaaccgctt taataaaaaa tccagaatat tctaacataa
    14161 atggagtatt cttagaatca aaaggagaaa gaagatggtt tatacttata cggagcaaga
    14221 aaagatgaaa gttttagaca cattcatgaa tgatggaaaa gtaaaacaag taccaagttc
    14281 aacaaaaaag aaatacatcc tattgaaaga agtcttgaaa cgctttgacc atggagtgac
    14341 ttatacagaa acagaggtta attcgatact gctgaacgta ttttctagtg gcgattatgt
    14401 cgaacaaaga cgttatctaa tcacatttgg ctttttcaaa agaagttcag acggtcgggc
    14461 atatcagatg atgggaattg aaaattagaa gttttaattt atactcattg aaaaaagttc
    14521 aagtatgcga tattggttct acaccgcata cttgaacttt ttttgtcatc tgtatctata
    14581 atacaaagcc aagaacgtta ttcaaaatat ggatagctat gataaaagct aatgagcgat
    14641 tcgcagttaa ataagcaatc gtcagtaaaa tcgttccagg agcgtacatg aaaaaatcaa
    14701 ttggatgcgt tacatgaata aagataattc tcttttattt gtacgaataa ataccaaaac
    14761 gtacctccta aaattagatt ttggacagat gccctttaaa aagataacaa gatttcgttc
    14821 ttgaaacaat atatatgctt ttattccaat gaggttgtga aaacagtatt ttgtcctgag
    14881 cgttagaaaa ttgaaaatgg ggaatagcaa ctcgtacttt accatttttt aagtgaatac
    14941 aagatcagct aattgaacac cgtttattcg tgatgaggga cacaacactg cagtcgacac
    15001 atttctcttt tatgttcaaa gataacaaat atttaaaaca aagaaaaata gtagataatc
    15061 ccgtcctaac tcttttattc ttccctcata gcttccaaat ttaagcaata cttcaattaa
    15121 tcaagtttta tctttttttt tcaataatcg taaaaaaaga gtatttttta tttaaaaata
    15181 aaatctttgt attaaaggac aagactaaaa taaccttaga ataaaaagag aaaa
//
LOCUS       DAFEIE010000062        15139 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFEIE010000062
VERSION     DAFEIE010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.064"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..344
                     /locus_tag="LP345_002172"
     CDS             <1..344
                     /locus_tag="LP345_002172"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760942.1"
                     /translation="NIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQDK
                     KNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQKK
                     RDNNDQYLPKK"
     gene            425..1045
                     /locus_tag="LP345_002173"
     CDS             425..1045
                     /locus_tag="LP345_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760943.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            1746..2030
                     /locus_tag="LP345_002174"
     CDS             1746..2030
                     /locus_tag="LP345_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760944.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            2033..2950
                     /locus_tag="LP345_002175"
     CDS             2033..2950
                     /locus_tag="LP345_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1760945.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            2943..3725
                     /locus_tag="LP345_002176"
     CDS             2943..3725
                     /locus_tag="LP345_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760946.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            3726..4406
                     /locus_tag="LP345_002177"
     CDS             3726..4406
                     /locus_tag="LP345_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1760947.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            4399..5295
                     /locus_tag="LP345_002178"
     CDS             4399..5295
                     /locus_tag="LP345_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1760948.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            5490..7139
                     /locus_tag="LP345_002179"
     CDS             5490..7139
                     /locus_tag="LP345_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL1760949.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            7733..8668
                     /locus_tag="LP345_002180"
     CDS             7733..8668
                     /locus_tag="LP345_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1760950.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            8661..9431
                     /locus_tag="LP345_002181"
     CDS             8661..9431
                     /locus_tag="LP345_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1760951.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            9847..10830
                     /locus_tag="LP345_002182"
     CDS             9847..10830
                     /locus_tag="LP345_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBL1760952.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            11277..12311
                     /locus_tag="LP345_002183"
     CDS             11277..12311
                     /locus_tag="LP345_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1760953.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTRAGS
                     NQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKILV
                     INGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELGI
                     DQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMFA
                     KTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHMLG
                     KVVVSGPFNG"
     gene            complement(12400..12723)
                     /locus_tag="LP345_002184"
     CDS             complement(12400..12723)
                     /locus_tag="LP345_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL1760954.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(12710..13417)
                     /locus_tag="LP345_002185"
     CDS             complement(12710..13417)
                     /locus_tag="LP345_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL1760955.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            13503..13844
                     /locus_tag="LP345_002186"
     CDS             13503..13844
                     /locus_tag="LP345_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBL1760956.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(14015..14863)
                     /locus_tag="LP345_002187"
     CDS             complement(14015..14863)
                     /locus_tag="LP345_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760957.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         4853 a         2579 c         3199 g         4508 t
ORIGIN      
        1 caaatataaa aactagtacg aaattaattt gtaaattatt taagcttgat aaaataagca
       61 atatcgatga tgtaaagtcc aagatattaa caagaaaagt aagcgaacca gtaaagctaa
      121 cggcacaaga taaaaaaaat ggaattgttc tttatggtga tgatgcaaag tataactata
      181 attgggatac ctcctcagaa gctgaggtat taagtattcc tactaccgat acttcagggg
      241 aaaaagtcac ctttaaaata aattttataa cggcaatttc taagttggag tatgggaagc
      301 aaaaaaagag agataacaat gatcaatatc tacctaaaaa ataacgaatt aatgatgcat
      361 atgttaaagt tgtttttttg aattaaacaa ctcaatttat tcagttatat gttcatcgca
      421 gcaagtgaac attaatcgag ttataaaatt aataggagct aaaaatataa ataaagttcg
      481 atcagaattt atttttccag aagatttttt taactggttt ttttatcaat tcagtgaatg
      541 caagcgactc ttaggtgaga attattactt aaaaggaatc ggcggattta tggggaatgt
      601 ggctgatgaa caaaatatta taaaaggaat atctgaacaa acatcagagc ttacagtaac
      661 taaagcattt ataagtaatg gtgaaagttt gaaaaatgta actgcgcgaa ttagaaaaga
      721 aaatgaagta gacattgttt ttggaattga ccatgaatgt aattcagtga tatatgtaac
      781 acaatcagca aatttaattc tttttgagaa tggttgcaag gacgatttta tggtggtcta
      841 tttgtacgat atactaattc caaaacttcg ttccttatat atgtcttctg aaagtatttt
      901 tgtgagtgaa caaaagggat ctttctcgaa aaaaataggt attgaagtaa ttgaatcgat
      961 tatgtgtcat aatcatatta cgctagaaga attagaaatt ttgatagggc aaaaaaataa
     1021 taacacgaaa atacaagttt cttagaaatc attttttatt gagatatcta gataaatgat
     1081 ttattcttca atcaaccaac tcgccaagct gaggtaatgt tttgaggtaa tgataacata
     1141 caacttttta taccctagta aaactctata aacaaagact tattaatttc gcatgaaata
     1201 cattcctgta aaatgcaata aaatagagtt ttgtttaacc aggtcttaag aaagcccgta
     1261 aagcttcaca gttctcaaaa cgttaattgc gattatcgtt cgagttcacg agttacgaga
     1321 atcgtactgg gcgaagcaat gctgagcgca gttaccttaa tcctaacttt tctggcactt
     1381 tccacaattt ggaaagtgcc ttttttgtgt ttttagctat gttaataggt aggattcttg
     1441 gtctataata tcattcgatc tataaacaaa cgggaaaaag ataaagtatc atcaaacaat
     1501 attatttatc cgcttctgag gttgtgacag aagtggtcag cttcaagaaa taagaaggaa
     1561 tttacaaaaa ttgcttctca tgtttgataa atattgtgac ttgtgaccga ggagttggca
     1621 ggagaacacc gtttattcgg aagaagggat tgtgaaaagt cttttgtcat aacctcttat
     1681 ttggtagcta attgtaaatc ccaaacggca tgtattattt ttcataagtc cgtttttaag
     1741 gattaatgtt ttcttttgct ttttatatgg tctggcttca gcgagaagtt ccaacgcata
     1801 tacaaggacg tctgatgtca acgataacaa cgattaccat ggtggccagt ccacttggat
     1861 tagcactgtt tggtgcgctc tttgattggc agacaactca accacgtctg cgagacagtc
     1921 tgatttttct tgaaattcaa ttggaaaatt tacactttct ttatacattt ctggctgctt
     1981 tctttatacc cgtcaactat acttcactta tcaataagaa agaaggataa gtatggattt
     2041 tggaaatgaa acggtcttga aagcaactgg tataaccaaa aaatacggtg ctgccaaagc
     2101 attagataaa gtatcgatcg aaatcaaacg tggaatgatc tatggtttga ttggggagaa
     2161 tggagcgggt aagtctacct ttatgagaac tattatgggt ttgatctcga ttgatgaagg
     2221 ttcgatcgaa ttatttggaa cgacggattt gcaggcagca agacgacgta tgggtcaatc
     2281 gattgaaacc cctgctcttt atccagaatt aactgcaaga gataacctac gtatccaagc
     2341 agcgaacggc ggtgtgtcgg atagagaaat cgaagacctg ctgaaaatga tgcgattgga
     2401 aaatacaggg aaaaagaaag caaagaattt ctctttaggt atgcgccagc gtttagctat
     2461 tgcaaatgca ctgatcacga atccagaatt tttgattttg gatgaaccga cgaatgggat
     2521 ggatccagca gggatggcag aaatgcgaga aatcatccaa cgtttggtaa aagaacgggg
     2581 catcaccgtc ttgctttcta gccacttgct agatgaattg tcacagatcg ccactcacta
     2641 cggtattttg catgaaggac acttgatcaa agaattatcg aaagaagaat tggcacaaga
     2701 atctcgtcaa tttataaaaa ttgacacttc ggcgacggaa caagcagtaa cggttctcga
     2761 ctctcttggt tatagggatt attttgtcca atctagccgt gttatccagc tttttgaagg
     2821 aattgaccaa gtagcagcca tcaatcaagc attggtagag gcaaaagttc ctgtggatgg
     2881 tatccaccta gttgggcaaa aactggaaga ttatttctta caattaactg gaggcaatcc
     2941 acatgtttaa tctattaact gctgaaaaaa taaaagtatg gaagagccgt aaaatgtggg
     3001 tctcactagg actgatggtc gtacttccgc ttttttattc ttggaacgaa tggtatatgc
     3061 atacaaaata cggcaatgaa ttaaaccaag caacggatac agtcatcaac ggtgcaacag
     3121 ggattttaat ggtggaaaaa atggctgcat ggattcttct ggctttcgca gcatttgcgt
     3181 gcttttatat tggggaagaa tttcaaaacg gtacgattcg caatacgtta tctttaggac
     3241 ggaatcgaat gacttattat gtgtcgaaac ttctcgttac gcttttgatc acaacacttg
     3301 gcgtggtttt gattacgggg ctagccatga ttgcttacac acttgctttc ggatttggtg
     3361 aagttgaggg aatcaaaaac tatggaaatt atgttctaaa agtatttcct gtattgcttc
     3421 tgctgatatt agcgacatta tctgttccag tggctttgac attcatcact agaagtacca
     3481 gtgtcagttt gcttctttct tttctttata tcatgggaac ggccttcgtt cccggtgttt
     3541 tcgcaaaaat caaaggcttg gaatttctaa cggagtggtt tacggaaacg tggctcatgt
     3601 atacggactt tgcgcaacaa gcaacttatt cgcaagcacc gaaaatgatt ctggtcagtc
     3661 tagtaacaat cgtggtatca tcagctctag gaatgtttat tttccaaaaa tctgacatta
     3721 agtaggtgtt cctgctggaa actattttga ttatcgaaga cgatgaagct gttcattctt
     3781 tactggagga ggttcttgaa cagagataca aacttcttga tgcttattca ggtacggaag
     3841 gaaaattatt gttaagcaca tatcctgtcg atttgatcct tctagatctc atgcttccag
     3901 ggctttcagg tgaagcattg ttagcagaaa tccgacagac atcgaatgtt ccgatcatcg
     3961 ttctttcagc aaaaagcgat caaagagata aagtttcctt gttggcagca ggagcggatg
     4021 actatgtgac gaaaccattt gatatcgaag aactgttgtt acgaatcggc atccaacttc
     4081 gtcatcagac ttctgtccaa gtaaaagatc tgtcgcaacg catctattac aaggaaatct
     4141 tactggacaa agagtcgagg gatgtaaatg tgaatggtgt ggctgtccat ttgacaggaa
     4201 gagaattcga tctgctgaag ctttttttag aacatccgaa aaaagtattt tcgcgagcaa
     4261 atctttatga aacagtttgg caagaaccat attttgatag tgagaaaaca gtgaatatgc
     4321 atatttccaa tcttcgaggg aaactagcaa aggcacatgc tgtgtatatt catacggtgt
     4381 ggggagtggg gtttagattt gattaagtgg ctgttgcttc tcgttgttat ctttatggga
     4441 agttttattt tcttcctgca aagggaaatc aagagattaa ctaagaaaat cgccactctt
     4501 tctgaacgac aagaatatgg tggtcgtctt tcagtcgaat ttcgagaaaa gaatctaatg
     4561 gacctagtag atgcactgaa tacatgggtg gatgaaaatg aacaaaaagg acaagcattt
     4621 caagaaatgg aagaaaacat cagactatcg atcgtcggcc tttctcatga tctcagaact
     4681 cctttgactg ctattaacgg ttatgtacaa ttactggaac aggtagagga tacggagaaa
     4741 cgggagaagt atttaacgat catcaaacaa tctgttgcaa gattactcag tatgacggat
     4801 cagttttatg atcttgctcg aatagagacg aagcaaaaag aaatggatct ccatacgctt
     4861 tctttttcta aagaggtgga agaagtattt ttctcttttt atgaacaatt ttctgagaaa
     4921 aatatcgagg tagcgttcgc tgaacactcg ataaatacaa ctgtattagc agatccgctc
     4981 atgttgctgc gagtgctgca aaatatcata cagaatttat tgcgttatgc agatggacaa
     5041 gcaaaggtga cattttcaaa agaggattca ttcattcgat taacagtggc caatcctatc
     5101 aaaccaggag cgcaaacctc tgttgaaaaa gtcttccagc gtttttatac cgaaaatacc
     5161 agccgcacaa atacggaatc tagcggaatc gggctttacc tgtcaaaaaa attggtggaa
     5221 ggaatgggag gagagatgac cgctagatta gacgggggca tcttctccat ctccgtcaag
     5281 ttgcggaggg tttaattggc tctaatttac ctgaagtgaa tgacaaaaaa ttgtatctcg
     5341 ttttaaagac atcttctttt ttggaaggtg tttttatttt ggtgtgattg atacgaatta
     5401 ggtaacgaag acagttattt ttgtaccccc ttttcaaata gcgcaacagt gctatactaa
     5461 aactaacaaa tcaaggaacg gagagggata tgggccaaag agaatttatc gttttaatta
     5521 ttattgcagt tgttatttta ttagttgttt tagacatttt ttcacgtttg aaagtaaagg
     5581 aaacagttcg tagtaattgg ggaaaaattc cttatcaacc gagatttgat aaagaagaaa
     5641 gtttgaagga tgcgtggctc acggagaaaa aattccgttc atgggatagt gaaatcgacg
     5701 atcttacttg gtatgacttg gatatgttcg aagtatttga agggatcaac agtacctatt
     5761 ctagtgtagg ttcagaagcg ttgtatcagc gtttacgtag ctttgatttt ggagaagatt
     5821 atcagttaga aaaactaatt gctttttatc aggaaaatcc tcaactgaga gaaagaatcc
     5881 aatatcaatt cgctcgttta ggaaaaaaag atcataattt tgcaaaacaa tatctagcgg
     5941 atggaaaaag taaaaagatt ggacgcgtag gtttatttat ttttcttggc ttgcttccgc
     6001 tggtgggtgt aggtttgctt cttttagggc aagtactagg aatctatcta gcaatcggtg
     6061 gcttagtatt caatacggtc tattatctag tgaagaaaca aacactagaa acagagctga
     6121 atagcatgag ttatttggtt tcaacgattt cagccgccaa tcagttagca aaaatgacga
     6181 caccacttca aaaagagctg aaacagcaaa ctaaaccatt aagagacatc cctaaattag
     6241 gtttttcatt tcgaatgaag agcgggagtg aagcagaatt gatttttgaa tatgtcaaca
     6301 tcatgttcat gctgccattt atctcctatc atttcgttct cactaaatta gaaaagcatt
     6361 caactgaagc catcaagctg tgggaattgc tgggagaatt ggaagttgca gcagccgttt
     6421 tgaattatcg cacctatatg ccgatcactt gccgaccaga gtttactgag ggcggtgtga
     6481 cagcgaaaga tatctatcat ccattgttaa aagaagcggt agttaatcca gtcaactggc
     6541 agaagaatac attagtcacg ggttccaatg catcaggaaa atctacgtat gtcaaaagta
     6601 tagccatcag ctgtattcta gcacagacga tccaaacagc gattgcagaa cagtttaccc
     6661 tgcaacctgg acatgtgttg acttccatgg caatcgaaga tgatttattt gaaggcgaca
     6721 gttattttgt ttcagaaatc aaatcgatca aacgtttgct ggaccaagtg gcttccaaag
     6781 aacgctgcta ctgcttcgta gatgagattt taaaaggaac aaatacgatc gaacggattg
     6841 cttcttccgc ttcagtcgtt cggtggcttg cggagtatcc atctttagca tttgtcgcca
     6901 cacatgatat cgaattgaca gagattttaa agaattattg tgagaatgtc cactttgaag
     6961 aacaagtaac agaaggaaaa ggaatcagtt ttgatttcaa attaaaagaa ggaccttcaa
     7021 ggacccgaaa tgcgattgcc ttgctgaaag ttttgaatta tcctaaatcc atagttgaac
     7081 aggcccaaaa agaaagtttg ttgttcgatg aacagcgtca gtggtatccg tttgattaac
     7141 tttatcaaac gaagcatgat gcgtgggtcc aaaaagacga ttatcaaaag aagtacattg
     7201 atgccaaaaa agtggcagaa ttcaatggga acgagtctgc tgtccagatg atcttggaag
     7261 atttagcaaa agacgataca aaataaacca cgctgtcttc cttctagcag cttttatcga
     7321 aaaaacttag catcagcgac gagacgcacg ttccatggca aagttctccg taaaacaaac
     7381 agcgaaaaca gaaattgaaa ataactattt ccattttatt tatttcggtt aaaataaaag
     7441 aaaaaagctt tcgataaaag gacggaggaa agcttaacat gaataaaaaa gacaagaacc
     7501 tcagttataa ggatcttcta tatgtcatcg tagtagttgc tgtcggtact tttatgattt
     7561 taaaagttcc agagttgttt agatagttat tctatcgaag atgatcatga actagaaaac
     7621 acatctcctc tttgttagca ggtgtgtttt tgtgtggaag ccaagttgtt ttttcatctg
     7681 ctgtattcca tgatacaatt aagaatcatg tctataagga gataggaaat aaatggcaaa
     7741 tgcgcttgaa ataaataatt tgaaaaagat ctatggaagt ggggtcgaag cattgcgggg
     7801 aatcgatctt tcggtgaaag aaggagattt ctatgcgcta ttagggccaa atggagctgg
     7861 gaagtctaca acgatcggga ttattacttc tttagtcaat aaaacatctg gaaaagtgaa
     7921 tgtcttcggt tatgatctgg acaaggatct agttcgagca aagcaacaga ttggattggt
     7981 tccacaagag ttcaatttta acccttttga aacggtccag caaatcgtcg tgaatcaagc
     8041 aggctactac ggtgtctctc gcaaagaagc gatgaaacgc agcgaaaaat atttgaagca
     8101 gtccaatctt tgggaaaaga gaaatgtccg tgcacgtatg ctttccgggg gaatgaagcg
     8161 aagactgatg attgctaggg cattgatgca tgaaccacgt ttgctgatct tggatgaacc
     8221 aacagcagga gttgacatcg agttgagacg cgagatgtgg gagtttctac gagaattgaa
     8281 cgaaaatggt acaacgatca ttttgacgac gcattatcta gaagaagctg aaatgctttg
     8341 tcgcaacatc ggaatcatcc aatcgggtga actgatcgag aatacaagta tgaaagagct
     8401 tctgtcaaaa ctgcaatttg aaacatttat ctttgattta gcgccatatg ataccaaacc
     8461 tgtgattgaa ggatatgctt gtacatttga agatgagcag acaatcgctg tcgaagttga
     8521 acgaaatcaa ggggtgaacg gaatcttcga tcagcttaca agacaaggaa tcaaagttct
     8581 ttctatgagg aataagtcga atcgtttaga agaactgttc ttgaaaatca cagaagaaaa
     8641 taatcatacg gaggagaaaa atgtttaatc tttattttac tgcattaaaa agtttagcta
     8701 tcaaggaaac gaaccgctat ttgcgtatat gggtccaaac actggttccg ccagtgatca
     8761 cgacatcctt gtattttgtt attttcggaa aaatgatcgg tgggcggatc ggtgacatgg
     8821 gtggtttttc atatatggaa ttcatcgttc ctggtttgat tatgatgtct gctatcacta
     8881 gttcgtatgc caatgtttct tcgtccttct tctctcaaaa atttcagaaa aatatcgaag
     8941 aaatcttggt agcacctgtt cctacgcatg tgattatttg gggctttgtg attggtggtg
     9001 tgggtcgcag tattctcgtc ggctctctcg taacgatcat ttccttgttc tttgtaccac
     9061 ttcatgtgta ttcatggttc atggtcatca ttacattatt gatgacggca atcttgtttt
     9121 cattagcagg actgctcaac gggatttttg ctcagtctta tgatgatgta tcgatcgtgc
     9181 ctacatttgt cttgcagccg ttaacttatc taggtggcgt tttctatgcc atctctatgt
     9241 taccgccctt ttggcaagct gtttcaaaag tcaatccgat cgtttatatg atctccggtt
     9301 tccgttacgg attccttgga acgatcgatg tgccagtagc aacatcgatg atcgtacttg
     9361 tgttattcat cgttgttttg tacgccgtta cttggtattt gatcaataaa ggaagaggat
     9421 tgagaagtta gaaaagaggt tgtgaaatca gcgttttgac ctgagtatta gagaaacaaa
     9481 cgggaaaata gttcctcata ttttgttgtt ttttgagcga ataccgaggg tcagctgatt
     9541 gaacaccgtt tagtggagag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
     9601 caaacaaaaa tagctcctcc tatttttcgt ttggttggac ttattaccgc agatgcaagc
     9661 ttttgaacac catttattcc ggaaaatgga ctgtgataag atttttgtca cagtcttttt
     9721 tttgctcaat cagaaacatc ttttaagctg ttcactttgc ttcttttttt gtttcctagt
     9781 ataatgacaa tgtttttgag aaagattgcg acttcactgc ttgatagaat ggagagtaac
     9841 aaataaatga ctactaattt ttggaaagag ctgccaaagc ctttttttgt tttagcacca
     9901 atggaagatg taacagatgt tgtatttcgc catgtcgtaa agcatgcagc agcaccggat
     9961 gtcttcttta ctgagtttac aaactcagac agtttctgtc atccagatgg aaaagacagt
    10021 gtacgaggaa gattaacatt tacagaagat gaacagccga tggttgccca tatttgggga
    10081 gacaagccag aattttttag agaaatgagc attgctatgg cagaaatggg cttccaagga
    10141 atcgatatca acatgggctg cccagtccct aatgtagcag aacgtggaaa aggcagtggc
    10201 ttgatccttc gtccagaagt agcggcacaa ttgattgaag cagctaaagc tggcggtttg
    10261 cctgtcagcg tcaagacgcg tatcggctat acggaaatgt ctgagatgga agaatggatc
    10321 agtcacctac ttcatcaaga tatagccaat ctttctgtcc atttgcgtac gcgtaaagag
    10381 atgagtaaag tagatgcaca ttgggaagtc attcctaaaa tcattgcttt acgtgaccaa
    10441 atcgctccac aaacactaat cacgatcaat ggagatatcc ccgatcgcca gacaggagaa
    10501 gaattggccg agaaatatgg cgttgatggc atcatgattg gccgagggat tttcaagaat
    10561 ccttatgcat ttgaaaaaga cccgagggaa catacagaaa aagaactgat cggactactt
    10621 cgtctgcaac tagatctgca agatcattat tcagaaatca tcccgcgttc catcacagga
    10681 ctacatcgtt tctttaaaat ctatatcaaa ggatttccag gagcaaatga cttgcgagtt
    10741 cagttgatga atacgaaatc tactgatgaa gtacgagaga tcttagagac ctttgaaaaa
    10801 gaacatccaa cgcttttcag tgaacaatga tttcttgctt gaacaccgtg aattagaggt
    10861 cgtgaaaaag ctgtcctgta tcaagtaata agaacagcca aacaaaaata gctcttcata
    10921 ttttgtcgtt ttttgagcta ataccgaggg tcagttgatt gaacaccgtt tatatcagag
    10981 gttgtgagcc tgccgtttaa ctctgagtca caaggagcaa tttcaaaaaa cagcttctca
    11041 tgtttgatga atattttgac ttgtgaccga agagttggta ggagaacacc gtttataaga
    11101 ggttgtgaca aaagtcttgt cgcaacctct tttttaacca aaaaagtgca aatagtttac
    11161 tttaagtaag agaataatta tgatgaataa aaaaggtgga acaaatagca tactatatat
    11221 attgaaatga acactgtatg gatgctccaa cttgatgaag ctaaggagga attcgtatgt
    11281 cagaaaagga attaatgaag gtagtcggtt tttatgaagg gttgccgatc gatgatccaa
    11341 aaagctttat tgatgaaaaa gaacagatac ctgtacccag ttcacgggat cttctggtaa
    11401 aagtcaacgc agtatctgtt aatcctgtcg atacgaaact tcgccaagat aacgggataa
    11461 gaaatgcttt acgtatctta ggttttgatg gagtcgggaa agttgttgct gtaggtgacg
    11521 aagtgcaaaa attttctgtc ggcgatcgcg ttttttacgc aggtacaaca agagcaggaa
    11581 gcaatcaaga ataccaacta gttgacgaac gtattgtcgc tcttgcacca aaaaatcttt
    11641 cagatgaaga agctgcagcc ttgccgttga cctcattgac cgcttatgaa ttgttatttg
    11701 aaaaatttgg tctaactcca gaagaaaatg ccaatcgcgg gaaaaaaatc ttagtgatca
    11761 acggatccgg gggcgtcggt tcgattttga atcaactagc gcattgggct ggcctagaag
    11821 tctacgcgac tgcaagtccg aagaattttg aatggctgaa aaaaacaggt gtagactatc
    11881 caatcgatta tcatcacgac ttaagtaaaa gttttcgtga attaggaatc gatcaagtag
    11941 agtatgtcgc tgtattattc gatattaccc gctactttga tcaaatcaag caccttgtcc
    12001 gaccatttgg acatgtggga acgatcgtag ggatcaaaga gccgttagat ataggtgttt
    12061 ggaaaaacca atctatcagc ttcgactggg agtatatgtt cgctaaaaca gactataact
    12121 atgaaatcga aacgcaagga gaagctttag cgcacattgc tgctttagca aatgaaggga
    12181 ttatccgcag tacattgagc aaggtctatt cagatgggat gaatgcgaag aacttgaaac
    12241 aagcaaccaa agacgtagaa acaggacata tgttaggaaa agtcgttgtt agtggtccgt
    12301 tcaacggata agcaagaata cgccgatttt tttcttattt gactttgata aaaacaagag
    12361 cgcatgacag taatttgcca taagctcttg tttttttatt tataataagc gaatcaacga
    12421 aagggaaaga attcctgcca agacgatcac caataagctt tttgaaagaa tagcagctaa
    12481 aagtgtagga actgaagcca aagcattttc gagattgatc tgcggcagat gtccgatatt
    12541 ttgggtaaat agactgctga accataaagc agacataatg acgatcggga caaaacttaa
    12601 atactcaagc aacggttgcg gtaaatcgaa ttttttcagt aagacaaatg gtaggaccct
    12661 agaaagccaa gttgctaaag tacaacctaa aatagtcagc aatgtaaact caaaagaagg
    12721 catgtttgat ccacaccccc aatccgcacc caatcagtgt tacaactaca atcactaagt
    12781 tgcttgggat aaaaatcagt ccgacatata ccagaatcaa agtgagacca atcaggatca
    12841 actgtaatcg tttagaggtg tttctatcag aaatgacttg aagataaagt aacccgataa
    12901 acatagcgac gatggcgaaa tccaaaccaa actttttcgg atcagtaata aaattcccta
    12961 aaagtgcgcc aacaagagaa gaacccaccc acgtcaaata agaaatccaa ttagctgtat
    13021 tcatccaacg aaagtttaac ttttgtccag tatagttcaa tttattcatt cccagtgcga
    13081 aactttcatc tgtcagcaat gtgccaatca gcagattttg aagcagccga tttttcttga
    13141 aataaggagc aatcgtcata ctcatcagaa tcattcggga attgactaga aaggtcgaga
    13201 aaacgatgga aagcaatggg ctgtgactag caagcatgct gactgtgata aattgggcag
    13261 aaccagcata gaccagcagg gacatcaacg tgacgactag tggatgaaat ccggcagctt
    13321 tcccaacgat accaaatgca agtccaatac cgatataacc gaaaacggta ggtaacgtgt
    13381 ctttgatcgc agtttttata tctaactttt catccaataa caaaactcct ttagcacgac
    13441 ataaattttc ataattgtcg ttaaacttgt gaatattcta aatttttaat gagcatttgt
    13501 caatggtggg attgaaacgt aaagaactag cgggtcgcag atttacacgt attgtttcgg
    13561 tgggaggagg cgcgaaaaat cttgcatggc tacaaatcca agctgatatt ttcgatgcaa
    13621 cggtctattg tttaagtgtg gaggaaggac ctgcattagg cgcaacaatg attgctgcac
    13681 tagggttagg gtggttcgac acacctgaaa gttgttgtca gaattttatc caatatacag
    13741 atgcagtgga acctctctta caaaatgtag aaaagtatca taaaatctat caacaatgcc
    13801 ggaaaatcta tccagcaacg aaggaaattt gtcatgactt ataaaacaaa acgcgtacct
    13861 aatagtcaaa tgactaatat tgggtacgcg ttaagtcttc tttacttcat cctttgcatg
    13921 attcgtgttt ttaaagcaag gtctgctgta tttcttgtgg atttaggatg gttgttatcg
    13981 tttacttgct atttttcatt gaaatcgtct ttctttaccg tttctttagt tttttatcta
    14041 tttttttctt ttggttagaa aattcttttt cccgaaagtc ttctttcagg atttttatag
    14101 agtagcgttt tgaataagag gcgtcagtat gatcgacttg gcagacgaac caagagaaca
    14161 tttgcctttt ttctgcatga ggtgcttctg ctaataattc tttccataaa taataacagt
    14221 cctctatcag aagaagggtt cgttcatcct caggctccca atagaatgtt tcgagagtag
    14281 caatcacttc attgatcaat tcgaatgcgg gaagataggc attttgctga ataagcgatt
    14341 caactgcttc ttggatgaac tttcgcatct ccatgatgaa cttcgctgtt ttcctgtttt
    14401 tgtttttctt gataatatga tcgtatttat ggatgatagt tgttaattta tctgaataat
    14461 ttattgcatg aaatggcatc ttaactttga agcgttcgat aaagtgcgga tgttctataa
    14521 gaatctctgt taaaagctcc cgtacaagag aggaactagc ggaggaaaca agggacgaga
    14581 gttcggaaag tgagtagttg gattttttta ttggacgttc ttcgtaagcg aataagacag
    14641 cagccatgtg tttgcatttt tttccttcta tggcatatag acaatcacaa gtcatgttgg
    14701 tcttttcatc ccaagtgatc actaccttat aatcttccgt gccagaaact gttgcggaca
    14761 agtacttgct tgtatagttc aaatgacgga caaaaccgtg cagatgatag ctgtaaccgc
    14821 gttccaaaac gttttcagga aaatactcaa gccaattatt catctagttc tcctttcatg
    14881 aaacacttat ttatatttag tataaagaaa cgtttaagaa aaaagtagct gattttacat
    14941 atttgataat cacttttgct cgaattgtca aaaattcatt ctccttttct tttcttagag
    15001 aatgtgagaa aaagtaaaag aatagcgtgt tttaaagatg gaactttttt tgttttttat
    15061 ttatctgaca aaaatgaagt gattttgtta gaaataaata attgttccaa ttgataaaag
    15121 aggtatgatg tatcgcaaa
//
LOCUS       DAFEIE010000063        14901 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFEIE010000063
VERSION     DAFEIE010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.066"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     misc_feature    112..237
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            281..805
                     /gene="infC"
                     /locus_tag="LP345_002188"
     CDS             281..805
                     /gene="infC"
                     /locus_tag="LP345_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBL1760958.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            877..1077
                     /gene="rpmI"
                     /locus_tag="LP345_002189"
     CDS             877..1077
                     /gene="rpmI"
                     /locus_tag="LP345_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBL1760959.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1130..1489
                     /gene="rplT"
                     /locus_tag="LP345_002190"
     CDS             1130..1489
                     /gene="rplT"
                     /locus_tag="LP345_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBL1760960.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            1741..3048
                     /locus_tag="LP345_002191"
     CDS             1741..3048
                     /locus_tag="LP345_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBL1760961.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAIFA"
     gene            3125..5254
                     /locus_tag="LP345_002192"
     CDS             3125..5254
                     /locus_tag="LP345_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBL1760962.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKQQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            5229..5918
                     /locus_tag="LP345_002193"
     CDS             5229..5918
                     /locus_tag="LP345_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760963.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(6326..7012)
                     /locus_tag="LP345_002194"
     CDS             complement(6326..7012)
                     /locus_tag="LP345_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1760964.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(7148..7342)
                     /locus_tag="LP345_002195"
     CDS             complement(7148..7342)
                     /locus_tag="LP345_002195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760965.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(7392..7832)
                     /locus_tag="LP345_002196"
     CDS             complement(7392..7832)
                     /locus_tag="LP345_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBL1760966.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(7836..8681)
                     /locus_tag="LP345_002197"
     CDS             complement(7836..8681)
                     /locus_tag="LP345_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBL1760967.1"
                     /translation="MLINEQLVKRIITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            8830..10248
                     /gene="pepV"
                     /locus_tag="LP345_002198"
     CDS             8830..10248
                     /gene="pepV"
                     /locus_tag="LP345_002198"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBL1760968.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(10305..11252)
                     /locus_tag="LP345_002199"
     CDS             complement(10305..11252)
                     /locus_tag="LP345_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1760969.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(11475..11825)
                     /locus_tag="LP345_002200"
     CDS             complement(11475..11825)
                     /locus_tag="LP345_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL1760970.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            12025..13104
                     /gene="pepA"
                     /locus_tag="LP345_002201"
     CDS             12025..13104
                     /gene="pepA"
                     /locus_tag="LP345_002201"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBL1760971.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            13248..13568
                     /locus_tag="LP345_002202"
     CDS             13248..13568
                     /locus_tag="LP345_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL1760972.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            13590..14054
                     /locus_tag="LP345_002203"
     CDS             13590..14054
                     /locus_tag="LP345_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1760973.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            14259..14864
                     /locus_tag="LP345_002204"
     CDS             14259..14864
                     /locus_tag="LP345_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBL1760974.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
BASE COUNT         4739 a         2749 c         3116 g         4297 t
ORIGIN      
        1 gggaatcact gctagaaagt ctgctaatct aatcattttc agaaaaggaa gacaaactgt
       61 atgaaaaaca ttgacaaaaa gattagtttt tgctatacta tgatggttga gaaataaaag
      121 cagaagcacc cgcttctcgc cttagttgat aatgtcactg ggctagatag ttttcactgg
      181 ttctattagg tgaagtacgc gcgggttctg taagagaact cgttttttta ttgccgttta
      241 ttcggtaagc ttttctttct ctcataatat ttggaggtga atgaccatag caaaggatat
      301 gatggttaac gacggcattc gtgcacgaga gttacgattg atcggttcag atggtgagca
      361 attaggagtt aagacaaaag cagaagcatt gaatattgca gaacaagcaa acttggatct
      421 tgtgttagtt gcccctggtg cgaaaccacc agttgcgcga atcatggact acggtaaata
      481 ccgtttcgaa caacaaaaga aagaccgcga agcgcgtaaa aaacaaaaag tgatcaatgt
      541 aaaagaagtt cgcttaagtc ctacgatcga cttgaatgac ttcaatacaa aacttcgtaa
      601 tgcacgtaag ttcttggaaa agggcgataa agtgaaagct tctatccgtt tcaaaggccg
      661 tgccattacc cataaagaaa ttggtcaaaa agtcttgaat cgcttagctg aagaaactgc
      721 ggatattgca acagtggaac aaaaagcgaa aatggacgga cgcagcatgt tcttgacgct
      781 ggcaccgaaa aacgacagta agtaatttga atgactaact ggctgttgga cagccgatag
      841 tcggataacg aaagattttg aggaggaaat atagtcatgc caaaacaaaa aacacaccgc
      901 ggatcagcaa aacgtttcaa acgtactggt aaaggcggat tgaaacgctt ccgcgcgttt
      961 acaagtcacc gtttccacgg caaaacaaaa aaacaacgcc gtcaattgcg taaagcaagc
     1021 atggtttcta gtggcgactt caaacgtatt cgccaacaac tagcaaaaat gaaataagaa
     1081 gtacaaataa cagaatctga agatttattt ttattaggag gaattataca tggcacgtgt
     1141 taaaggtgga acagtaactc gtaaacgtcg taaaagagtg ctaaaattag caaaaggtta
     1201 ctacggttca aaacacactt tatttaaaac agcaaaagaa caagtaatga attcatacaa
     1261 ctacgcatat cgcgatcgtc gtcaaaagaa acgcgacttc cgtaaattgt ggattgctcg
     1321 tatcaacgca gcagctcgta tgaatggctt gagctactca aaattaatgc acggtttgaa
     1381 agttgctgaa atcgacatca accgtaaaat gttagctgac ttggctgtta acgatgcagc
     1441 agcatttact gcattggctg accaagcaaa agaagctttg gctaaataag ctaaacaatt
     1501 ataaagagga aagaagataa cgaaaagtta tgttctttcc tcttttttta tttacaatcc
     1561 tccatcaaat gaaacaggac aataacgtat aagtctaaaa tagcataatt aaggtttttt
     1621 aattgaaaac tgaacattta tggtcaccct ttaatgaaag cgctaactac ataagttaga
     1681 atgagtttga ctgatatatt agtttgctta tcagaaaaac aaaatggacg gaggaataac
     1741 atgagtgata ttattattgg tattttgtta gttatctcat tctttttcat ggtctggtac
     1801 tgtgtaaaag gctacaactt gatggtcggc tttgccatca tggctactgt atggatggga
     1861 ttagcgctag tcggaaacac gttttcacca aacccggcga tggaagggca aggagtaatt
     1921 gatgtgttga cgcatatcta tacgacgggg ccagctgagt acgccaaatc gatcttggta
     1981 aatgtcttct ttggtgcctt tttcgggcgt gttctagtag atagcggaat cgcagctacc
     2041 ctgattcgaa aggtagttga acttggaggg gacaagccaa gaatcacgat gagcttacta
     2101 tgtattgtaa ccgctgttat attcatgtcg atgacaggaa tcggaccagt gatttctatt
     2161 gcagttattg tgttgccaat cttgatgtca ttaggtattt cagtaccggt tgcactgttc
     2221 tcatttatgg gctcgattat ggctggaatc tttgctaata tcgtcaattt caaacaatat
     2281 caaacgattt atgctggttt caatccagcg gctgaaagct atacttataa tgactatttc
     2341 caaattggta tgattgggat gattgtaagc ttagttgtgg tactaacggt cgctaatata
     2401 tcaatgaaca aaaagaaacg ctatgcaatg gcagcaaacg taccagctga aggtggcgac
     2461 gcaccaatga tctcatggtt agccgtatta ttaccagttt taggggtcgt tcttttagat
     2521 cttccaatca tcttaggttt tattctagca ggtatctggg cattgctgtt tactggaaaa
     2581 ttgcgcggag gttataaaga aatctgtcgt cagtttgcga aattatttac agatggcgca
     2641 gtagatgttg caccaatggt tggtttcttg atgaccttag cgatgttcaa taattcagct
     2701 gcgtatgctt ctccttattt ttcagctatt tttggagatt ggataccgca atcaccatta
     2761 gtcttggcaa tcgtatttgc tatattgaca ccactaggat ttttccgcgg tccaatgaat
     2821 ctagtcggtt caggctcagc tattttagct gtcgtattag ctgttaatcc aacgatgtcg
     2881 ccagcctttt tgttcccgtt atttgcaatc acaacgattg ctcctcagca tttagatatt
     2941 acacaatctt gggttgcttg gggattaggt tatacaaaag taacttctcg agaatatatg
     3001 aagaaatcca tcccaactgg ttggatcatc ggagcgatct ttgcctgatc acgttcttat
     3061 tgtacgggaa cgcctagtaa acaaaacgtc gataaaaacg attagatgaa tggaggaaaa
     3121 gaaaatgaaa cgttttgtgc gaatgggaat tgatgttggc ggtacacata cgaaagcagt
     3181 cgcaatcgat aatgcgacgc acgaaatcat cggaaaatct tcagtgaaaa caacccacga
     3241 tgatgtccgt ggagtagccg caggtgtcgt tcagtctttt caaaattgtt tgcgggaaaa
     3301 taatatcagt ccagaagatg ttgtgtttgt tgcacattct accacacaag cgactaatgc
     3361 actgattgaa ggagacgtag caaaagtcgg cgtaatcggg atggcaaaag gtggattaga
     3421 aggtttttta gcaaaacaac aaactagatt gaacgatatc gatttaggga ataagaaaaa
     3481 aatagagatt gtcaatgcat tcttacctgt caaacactta aatgtagacc gtgtttcaga
     3541 aacgatttct tctttagaaa gagaaagagc ggaggtcttg gtttcttcta tggcatttgg
     3601 agtagataat ggggaaccag aacgagttgt ttatgaagca gcatcggtaa aatcgatccc
     3661 tacaacgatg gcttctgaca tcacaaaatt atatggattg acaagaagaa ctcggacagc
     3721 agcaatcaat gcatctattt taccaaaaat gctagatacg gcaacctcta cagaagattc
     3781 cgtacgagaa gcaggggtca atgtttcttt gatgattatg cgcggagacg gcggagtaat
     3841 ggaaatcaat gaaatgaaaa aacgacctgt tttaaccatg ctttccggtc cagcagcatc
     3901 agtcatgggc tctttgatgt acttgagagc gtctaatggt gtttattttg aagtaggcgg
     3961 aacaacaacc aatatcgggg tcattaaaaa tggacgtcca gcaatcgatt attcaattgt
     4021 aggtggccac ccaacatata tctcttcatt agatgttcgg gttctaggtg tggcaggcgg
     4081 ttcgatggta cgggctaatc agtcaggaat catcgatgtc ggtccacgtt ctgcacatat
     4141 tgccggtcta gattatgcag tatttacgga gacagaaaaa atcaaaggtc ctaaggttga
     4201 atttttctct cctaaagaag gagaccctgc tgattacgtc aaggtagtga tggaagacgg
     4261 agaagaagtg actattacaa atacatgtgc agccaatgtc cttggattag tgcaagaaga
     4321 acatttttct tatggaaatg tcccatctgc acgaaaagcc atccaagcat tagctgatta
     4381 ttgtcatacg acggttgaag acatcgcaga acagatcatg gaaaaatcct atgctaagat
     4441 tgaaccggtg attttagaat tggcagacaa gtatcacttg gagaaagatc agatttctct
     4501 tgtaggtgta gggggcggcg ctgcctcatt gattacttac tttagtaata aaatgggtgt
     4561 gaaatattcg attcctgaaa acgccgaagt gatttcttct attggtgtag cacttgcaat
     4621 ggtccgagat gttgtagaac gtatcatccc ttcgccaagt aaagaagata tacgatcgtt
     4681 gaaaaatgaa gcgatgaata aagcgattga atcaggcgct acaccagaat cgatcgaagt
     4741 ccacgtagaa atcgatccac agacttcaaa agtaacggct atcgctactg gttctacgga
     4801 agtgaaagca accgatctaa ccaaggagat cacaacagaa gaagcactag agcttgctgc
     4861 agaggatatg cgattaaata aaaatgaagt ttgcttattg gaaaatacac ctttctttta
     4921 tgtatgcggc gaacagaatc gttcaaaaaa tgctggaagt cttcggatca tcgatcaaaa
     4981 aggatttatc aaggtccaac gtggacatgc ttcatgtatg aaaacaactg cagccaatta
     5041 tatgacagct gtcgaacaac tttgggaaga tatggcagtt tatcaaactg aattgattgc
     5101 ccgaccagaa ttttatctct gcttaggagc aagagtctct gattttacag cgacggatct
     5161 ggaacaacta cagcttttga tggatctgga agtatctact atggaaccgg aggaagaagt
     5221 gatcgtcgtt gccggaaata tcaaacaaac ataagttaga agagttacta aacgaattac
     5281 aacagatccc cgaagaaatt tggggattct accagtttcg gcgagattta ttttggaaaa
     5341 agattccttt gtccaagcag aaaattctta tacaacaatc aatcgattgt ggtatcgaaa
     5401 cggcatgtag catcaaaaaa aagtaccctt ttgccgatgt aggagaaatt tgtgaacaaa
     5461 tggctgttcc aatcgtttcc tgtgaatcag agcaaataaa cgaacgaatc acttttgcaa
     5521 cttatgcaga agatgaaggg attcgattga tgacggagcc gttagaaaaa ttaaaatgtt
     5581 caggactagc ttcgatctct aaagaaacag cgcaagcttt gattattgga catgaactat
     5641 ttcaccacat cgaagcttct gttaagggaa tttatacgca aagcgaaaaa attgtgctgt
     5701 ggcggttgcc tttttataca catcaatcaa acattcgtgc attgagcgag atagcagcga
     5761 tgagtttttc aaaagagatg aatcaaagcg atttttcgcc ttatgtatta gaggcagtct
     5821 tactttggcc atataatgaa attcgtagcc aagggatctt agaagaaata aaaaaaatag
     5881 aaaaaagatg tacggagtat gatttagatt acaaataaag agactgtgac aaaagtcgtg
     5941 tcacagtcct ttttttccga ataaacgatg ttctcctgtc aactcctcgg tcacaagtca
     6001 aaatattcaa caaacatgag aagctgtttt ttgaaattgt tccttgtgac tcggagatga
     6061 acggcaggct cacgacctct tggaaaacgg tgttcaaaag cttgcatctg cggtaataag
     6121 tccagccaag ttaaaaacat aagaagctat ttttacttgg ctgttcttat tacttgatgc
     6181 agggcagctt tttcacaacc tctcaataaa cggtgtgcaa tcagctgacc ctcggtatta
     6241 gctcaaaaaa aacggcaaaa tatgaggaac tattttgccg tttctttctc taatactcag
     6301 gtcaaaacgc tgattccaaa acctcttatt tgatgggtct gtcctgaata tcttcaaaat
     6361 aatcggggta attatgaatc acgtattctt gctcctcgat aatcatatgt aaatgcatcg
     6421 tgcaaagaaa tccgacttca tcaaagttat gatcaatcat tgattgaagc attgtctgat
     6481 gttcatctaa tactcgaccc cagtctaatt ctgaaatcgt caaacgtaac catctgaaac
     6541 ggttcaagtg cgtactataa ctttctagcc aatcccaaat ttctcgtttt ccagcaattt
     6601 cataacaagt tcggtgaaaa tcagtatcca aatcaaaaaa agctttttta ttttgagcga
     6661 ttactgcctg atcggtttgt tctagtattt tttctagttt agcttgatct tgcttggtca
     6721 ttttcgcact gcattcttgc aggatcggtt tttccaactt ttcccgcgta taacgggcta
     6781 atgaagcaga tcggatatcg atttttgaaa cataagtgcc ggactgtgga atggttttta
     6841 caagctcttg attgcgcagt tggatcagtg cttctcgaat cggtgtacgc ccgatagcta
     6901 gttgttcttc taacacttta tcggagattt tacttccagg tgctaactcg gaataaatga
     6961 tttgtttacg tatagattca taagcttgct gttgcaaatt attgataacc atttaacctt
     7021 cctttctatg cagatataat ctattataac ataaatcgct tacaaatcgt gtgggcataa
     7081 aaacacagtc tgcaaaaaaa gccctgatag gcatgcctat tagagcctcg aaaagaaaaa
     7141 tattgaatca atctggtcgt acctcttgta tcggtttgac acgaccgccg attcttttag
     7201 caaaagcttc ggattctttt ttgtctttga aaatgagcag attgtctaag tttttttccc
     7261 gagtgcgaca gccagtttta tcgatgtaac cgtgcattac tttaacgaca tacatgggga
     7321 tcacctgctt ttttcttttc attatacgaa ctactcgaca caatacaaga aaaatgctta
     7381 gacggtcttt attaagaatt tacatcatcc aaagaagcgt acgcttggaa taactgatct
     7441 aactccggat tgactttgct cagcttcact aatcgttgcg aatcagaaag taaaaaacag
     7501 tgtttactac tgccagtagt ttttaatttt ttgtcttcag ttcccacaat ttcgtagcta
     7561 aaatccaacc gtgtccccgt atacttttgg atagttggat ggatgctcac tttttctccg
     7621 taatggatca tttctttata gctgcaattt acttccagaa cggggatgat gatcccagat
     7681 tcttcgattt ttttataggg aaaccctaga tgtaccaata aggctacccg agcctcttca
     7741 aaccagcgga tataattgct gtgatgaata atccccattt gatctgtttc ataataaaaa
     7801 ggttctcgca cataacctgt aaatttctcc atgactcatg cctcgttttc cattgatttt
     7861 ttacaaaaat aattcatcca tttcggaagt gcttcgctga tttgtgtcgg caaaacaata
     7921 tattgttctt ttgccagctg gtctccaatg aaactatgaa gataaatagc tgctgcaatc
     7981 gtttggtcat tttgaggaaa ctgggctaaa aatcctgtga tcatcccagc taaagtgtca
     8041 cccatgccgc ccgttgccat agcagcagaa cctaaaggat tggtgtagaa gtgctggtga
     8101 ccataaattt ttgtctcatg acttttcaaa acgagcacag caccgatttc ctgttgcttc
     8161 tttttgtttt ctttatcccg ttgttcttgt atcggtagag aactcaaccg ttgccactcc
     8221 atttgatgag gtgtaagtac agtttgttcg ggatagggta gcaaaagatg attagcagca
     8281 agtaaactta aagcagagcc atcaatcacc agccattgtt cttttgattg gttttctagt
     8341 acttgtttga aacgttccaa actcttagaa gaagtaccca atccgggacc aatcaagagt
     8401 acatctgctt gctttattac ggaaagaaac tggtcagtat ccgtccaaac tacaatcatt
     8461 gcttctggca gatgactgtg aagagcactc cgattttttt catcagttac tacagtcgtg
     8521 agacccgctc cgctgtgtac ggcagctaaa gcactcataa tgattgctcc gccatattgt
     8581 tcattgccgc caatcaaaac gatacgtcca aatgttcctt tatgtgaaat ttttggacga
     8641 ggtgtgatga ttcttttcac tagttgttcg tttatcagca tctaaaaacc tccttttact
     8701 cattatagcg tatatttttt ttagagaaaa acagataaga aaaggaattg tcagattttt
     8761 tgaactattt ttttctgtaa tttgtggtat catgaacacg aagacttaaa taagtggagg
     8821 attaacttta tgacaattga ttggcaaaaa gaagtagaag cacgtaaaga agacttgctt
     8881 gaagacttga aaaatctttt acgtgtcaac agcgagcgcg atgactcaaa agtaacacca
     8941 gatgcaccat ttggacctgg acctcgcgac gcattgaaac atatgttagc ttatggcgaa
     9001 cgtgatggat ttaaagtaaa aaatgtcgat aactatgcag ggcatattga tcttggcgaa
     9061 ggagacgaaa cgctagggat atttggacac atggatgtcg ttcctgcagg agatggctgg
     9121 gacacagatc cttatgaacc agtaatcaag gatggaaaga tctttgcacg cggatcaagc
     9181 gatgacaaag gtccaagtat ggcagcttac tatgcgatga agatcattaa agaacttgac
     9241 ttgaaactat caaaaaaagt tcgcttcgta gtcggcagcg atgaagaaag cggctggggc
     9301 gatatggctt attatttcga acatgaagaa gaaccagatt ttggtttctc accagatgct
     9361 gaattcccaa tcatcaatgg tgaaaaagga aatgtttctt tagctttacg cttcaaaggc
     9421 gacaatgcag gagattatgt cttgaaatct tttgtttccg gacttcgcga aaatatggtg
     9481 ccaggaacag caactgcagc acttcaagta ccaagtgcag atgcagctat cgcgatggaa
     9541 gaagcatttt accaattcat cgaagcaaat ccagtaagcg gaacgattga agcggacaat
     9601 acgtatgtaa aaatcgaatt agttggtaaa ggcgcacatg gtgcaagccc acaatctggt
     9661 atcaatgcag gttctttctt ggcattgttc ttagataact atgaattcct aggatctgct
     9721 aaacaattta tccatgtagc agctgcttat gtccatgaag atttttatgg agaaaaacta
     9781 ggagtcgctt atgaagatga aaaaatgggc aaattgacaa tgaatgctgg actatttgct
     9841 tttgaagaaa atggtacaga ggaagcgaac ttcatcaata tgaatttccg ttttccaaaa
     9901 ggtgtaacag tagacggatt gcaaagtgac atcgaacaaa cagtggggca agaaggcgca
     9961 acagttactc gaggtgctcg cgtaatggaa ccacattacg taccaatgga tgatccattg
    10021 gtggctacat tattgcaagt ctatgaagac cacactggag aaaaaggcta cgaacaaatc
    10081 atcggtggcg gaacttacgg acgtttgttg aaacgtggcg ttgcttatgg agcgatgttc
    10141 ccaggatata ctgatacaat gcatcaagca aacgaattta tgagtcttga tgacttgttc
    10201 agagcaacag caatctatgc agatgccatc tatcgtttgg cgaaataatt aattaaaaag
    10261 aggatcaaga attgcaaatt atttttgcag tcttgatcct ttttttactt tctactgtgg
    10321 tattcatgat aaacatgata tagattcaat tcatattctt tcttagcgtt cgtgacgact
    10381 gtatccaaaa tcaaccctgt tactaatgaa agaagtgcta aagtcatcaa tccagtactt
    10441 aaaatcgcag aagggatgcg tgtaataaag cttgtcagca tatattcgcg aatcacagga
    10501 atccccgtga ccaatccaaa taaaaagaag aagatggtcc aaatcccaaa gaaaagcaaa
    10561 ggcttataat ctttaaacat tttaataatc atcatgatca ctttgaatcc gtcagagaat
    10621 gtattcaatt ttgattcgct gccttcagga cgatcacgat aatcgattgg gatttcaacg
    10681 aacttgaatt ttttatctaa agcatggatc gtcaattccg tttcgatttg aaaaccagaa
    10741 ctcataatag gaaaactttt gacaaagata cgattgaatc ctcgatagcc ggtcatgaca
    10801 tcaagaattt ttgttttata cattctagta attgtatttc taacaaggtt atttccaaaa
    10861 tcgtggaaag gtctcttatt ctcatcaaag taggttccat ttgataggcg atcaccaatg
    10921 accatatctg cttcaccaga acgtaatttc tcgagcaaac catgtacagc ttctgcagga
    10981 taagtatcat cgccatctac cattaaataa tagtcggcat cgatatcaaa gaacatttgg
    11041 cggatcacat ttccttttcc ttgacgaggt tcttttttta cgattgctcc accttgaacg
    11101 gccaattcgt atgttcgatc ggtcgaatta ttatcataga cataaatatc tgcttctggt
    11161 aattctcgtt taaagtctgc aatgactgtt gaaattgttg cttcctcatt gtaacaagga
    11221 atcagaacag caattttttc ttgttgttcc atttttcact ctccttaact atagaaaaca
    11281 aaagctaaat taaaaatacc tcataatcaa aggaaatgct agtttttccc gctaaatatc
    11341 atttatttaa aaagaaaata ctggaatata tgtttggaaa gctctatcta aaaaaccacc
    11401 cactacaaaa gaaggacatg atacctctct tttgaatagt gggtgcgtat tcgttctctc
    11461 acttttttga cgtattaatc tgttgcacct ttttttcttg aaatttctaa tacggttcct
    11521 gtatgagcat ctgctaaaaa ttcataataa acagtttcgc catcttctat tcgagaaaga
    11581 cctccccgat aagcactcga ccgaacggcg aatttcctaa taggttcctt ttcaaaagag
    11641 atccaagaac cttcgattgc accttctttt agaaaagatg acttgatatt ttcaagtact
    11701 tggtctgctg acaatacttt tttgcgatga taccaaatcg ttgaagctac cccgctcaat
    11761 aatcctagac cgattccaac tgctaacccg cctttaaaat agcttagttc gctttcttca
    11821 tacatgtgga catacctcct tcttctcact tgttactcct tgtgcttatt ttaccacact
    11881 ctcatatttt ctttgaaata aataaccgct accagaaaaa ataagctata ataaatacga
    11941 tcggtctgca gaaaaaatca tattttatcc gcagatcaat ataagtctga gaggagttta
    12001 gtctgaaatt tagacgaata gcatatggaa gaaaaaacat ttcaacgaat caaagagtta
    12061 acagaattac aaggaacaag cggttttgaa caagatgttc gcgcttatat ggaaagtcat
    12121 atggaaccgc tggtagatga gttacagtta gatggtttgg gcggcatttt tggtctgcgc
    12181 catcatgaag aagcggatgc accccgtgta atggtcgcag cacatatgga tgaagtcgga
    12241 ttcatgctga cacaaatcca agaaaacggg ctttttaaag tcgtacctct aggcggctgg
    12301 aatccttacg ttgtttctgc tcagcgtttt acacttaaaa cctctactgg taagaattat
    12361 ccatgtattt cttcttccgt tcccccacat ttattgcgag gaacaagcgg acaaaaatca
    12421 gtagaagtaa ccgatatttt gttcgatgct gggtttgaat caagagaaga ggcaatgagt
    12481 tacggtgtcc ttccaggaga cacaatcgtt ccttacgctg aaacgatcaa aacagccaac
    12541 ggaaagaata ttatcagtaa atcatgggac aaccgctatg gctgtacaat ggtattagaa
    12601 gctttagaag cgttgcaaaa tgaaacatta ggtcatacat tgattgcagg cgcgaatgtc
    12661 caggaagaag taggcttgcg tggttctaaa gcttctgtca ataaattcaa gccagatctg
    12721 ttctttgcag tagactgctc tgcagcagat gatacagtga cgaaaaatgg cacattcgga
    12781 catttaggag aaggtacatt gatgcgtatc caagatccag gtttgatcat gcttcctcgt
    12841 ttgcgcgagt acttgctgga tatcgctgaa acaaacaata tcccttatca atactttgtt
    12901 tcaaaaggcg gtacagatgc aggtgctgct catacacaaa acgaaggaat cccaagtaca
    12961 gtgattggcg tagtgggacg ttatatccat acgcatcaaa cgatgttcag tattcgcgat
    13021 tttgaagctg cacgagaaat gttgattcaa acactgaaag gtttggataa atcaacagtg
    13081 aatacgatcg tatacggaaa ataatgcgat agtgaaacta taaaatctgg caaaagattg
    13141 ctttttgcca gatttttttt ataaaaagag gatcaatgtt tgttagttcg aaagaaaggt
    13201 gtataattta attgaaaaat acataaacag aaagtagagg acaaagaatg attatcccaa
    13261 atagtttaga agaattagca ggctacgtag aaactggaaa gagtgtattt ttctttactg
    13321 ccggctggtg cggagactgc cgttttatca aaccgcaaat gcctgaaatt gaaaatgact
    13381 tttctgattg gcaatttatt gaagtagacc gtgacaagta catagatgta gccgctgaat
    13441 ggaacatttt tggtatccca agttttgtcg tgatccaaga cggaaaagaa ttaggtcgtc
    13501 tagtgaataa agatcgtaaa acaaaacagg aaatcgaatc gttcctagaa agtgtaacaa
    13561 aaggctgaca tctgttagga ggggtcaaga tgaatcaaga atataagaat attttagtag
    13621 gtatcgacgg tagtgaacaa gcacttgctg ctttcaaaaa agcggtagaa gtggctcgcc
    13681 gtaataatgg gaaagtatat gtagcaaacg taatcgatca gcaattttat aactttatgg
    13741 gctatgcacc tattgatcaa aatctagtcg atcagcaaac tgaaacagcc aaggaaatga
    13801 tcgaagaatg taaagaatat gggaaatctg ttgattacac aaatatagaa ggaattattg
    13861 catatggttc tgttcgtgaa tccatggcag tcaaattgcc aaaaaaatat gagatcgatc
    13921 taatcatggt tgggcagtca ggtctaaatg cagtcgaacg ctttatgaca ggaagtgtag
    13981 ccagctacgt gatacgtcat tcaccttgtg atgtcttgat cgtttctgac gaagaagaac
    14041 agccaagtaa ttaagcaagt ggaacttgta cgaccttttt aatcaattaa ctaaaacagt
    14101 aaagggactg tgacaaaagt cttgtcacag tcccttgtta cgaataaatg gtgttccaga
    14161 agaggcttct tcggaaataa agcatgaaaa aaatttcatg cagtgaatgc aattttttgt
    14221 taagataaat ctcagcaaag gataatggag gaaagaacat gatttttgct tataacaaag
    14281 cacacgtcgg agacaccttg atggttatta tagccgacga taaaggaaca gaaaacactg
    14341 ttgaacgcaa atggaatgtt gctcggatca aagatgaaca aggtcaagtt gttgcttgga
    14401 actttttcca tatctccgat catctaacaa tcgaagggaa cggccaagta agcttaacag
    14461 atgaggaatt agcgaaattg aatcgattga tcaaagaagc aggattcgaa gaacagcttg
    14521 aagctgatca tgaaccgaag atcgttgtcg ggtacgtaaa aacatgcgtc ccacatcctg
    14581 attctgacca tttatcgatt actgagacag aagtagacaa tggtacagta ttgcaaatcg
    14641 tttgcggtgc acccaatatc gaagctggac aaaaagttgt cgttgcaaaa ccaggagcta
    14701 tgatgccaga tggaatgatg atctggccag gaactttgcg aggggtagat agctatggaa
    14761 tgatctgttc cgctcgtgaa ttgcatttgc caaatgctcc agcaaaaaaa ggaatcttag
    14821 tattgcctga ggatgccgta gtcggagaag catttccaaa ataaagaggt tgtgacaagt
    14881 ctttgtcaca acctcttttt t
//
LOCUS       DAFEIE010000064        14548 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFEIE010000064
VERSION     DAFEIE010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.067"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            4..816
                     /locus_tag="LP345_002205"
     CDS             4..816
                     /locus_tag="LP345_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBL1760975.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="LP345_002206"
     CDS             813..1613
                     /locus_tag="LP345_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBL1760976.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="LP345_002207"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="LP345_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBL1760977.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="LP345_002208"
     CDS             3110..4819
                     /locus_tag="LP345_002208"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBL1760978.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9389
                     /locus_tag="LP345_002209"
     CDS             5031..9389
                     /locus_tag="LP345_002209"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBL1760979.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9534..10007
                     /gene="rimP"
                     /locus_tag="LP345_002210"
     CDS             9534..10007
                     /gene="rimP"
                     /locus_tag="LP345_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBL1760980.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10030..11205
                     /gene="nusA"
                     /locus_tag="LP345_002211"
     CDS             10030..11205
                     /gene="nusA"
                     /locus_tag="LP345_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBL1760981.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11227..11520
                     /locus_tag="LP345_002212"
     CDS             11227..11520
                     /locus_tag="LP345_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBL1760982.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11517..11828
                     /locus_tag="LP345_002213"
     CDS             11517..11828
                     /locus_tag="LP345_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBL1760983.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11841..14147
                     /gene="infB"
                     /locus_tag="LP345_002214"
     CDS             11841..14147
                     /gene="infB"
                     /locus_tag="LP345_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBL1760984.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLTSLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14174..14521
                     /gene="rbfA"
                     /locus_tag="LP345_002215"
     CDS             14174..14521
                     /gene="rbfA"
                     /locus_tag="LP345_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBL1760985.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4960 a         2583 c         3237 g         3768 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgagtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccacatccag ctaggacgaa
     5701 atattccagc cgatgaacca acgacaccaa tgatcagtat cgttgaagaa gaacgaagag
     5761 tcacacttga ggggtacgta ttcgacaaag aagtcagaga actacgttca aaacgcaaga
     5821 tcttgacttt gaaaatcaca gattatactt catcatttat cgtcaaaaaa ttctcgaacg
     5881 gcgaaaaaga tgaacaagta tttgatgcga tcagtgtcgg tagctggtta aaggtacgag
     5941 gaagtattca agaagatacg tttgtccgtg atttggtcat gaatgcgcaa gatatcatag
     6001 aagtcaaaca tacacctcgc aaagattatg ctcctgaagg ggaaaaacga gtagagcttc
     6061 atgttcatag caatatgagt acgatggatg caacaaacag catctctgat cttgtggcac
     6121 aagcagggaa atggggacac cgagctatcg ccattacaga ccacggtggt gcgcaagcct
     6181 ttccggaagc acatagtgct ggaaaaaaag caggtgtgaa aatcttatac ggcgtggaag
     6241 cgaatgtcgt agatgatggt gtcccaattg cttataatga tgcacatgaa gcattgagtg
     6301 aagccacata tgtcgtattt gacgtggaaa cgacaggatt gtctgcagta tatgacacga
     6361 tcatcgagct agccgcagtc aaaatgtata aaggaaatgt gatcgaaagc tttgatgaat
     6421 ttatcgatcc aggacatcct ttgtcacgaa caacggtaga tctgactggt atcacggatg
     6481 gaatggttcg aggatcaaag tcggaagaag aagtattgcg gatgttcctt gaattttcaa
     6541 aagatacaat tttggtagcc cacaacgcgg cttttgatat ggggttcttg aatactagct
     6601 acgcaaggta tggtattcct gaagcggcca atccagtcat tgatacgttg gaattagcta
     6661 gatatctgta tcctcaattc aaacgtttcg gattaggtgt gttatctaaa aaatttggtg
     6721 tcagcttgga acagcatcac cgagcaatct atgatgctga agcaactggt cacttagcat
     6781 ggatctttgt gaaagaggca atggacaatc ataacatgct ttatcatgat cagctaaatg
     6841 agcatatcgg agaaggagat tcttacaaaa gggctcgacc tttccatgta acgattttag
     6901 caaaaaatca ggcaggactg aaagatttgt tcaaactgat ttcaatgtcg aatgtcgaat
     6961 acttcgaacg cgtcccacga ataccacgct cccaattgaa aaagatgcgt gaaaatctat
     7021 tgatcggctc agcttgtgat aagggagaaa tattcgaagc catgatgcaa aaaggggtag
     7081 aagaggcaag aaaccgagca aaattctacg attatattga agttatgcca aaagcggtct
     7141 atgcgccttt gatcgagcaa gaattggtaa aaaatgaaca tgatttggaa gaaattatcc
     7201 aaaatttggt agaaatcgga aaaagtttgg ataaaatcgt tgttgcaaca ggtaatgtac
     7261 attatctgaa cgaagaagat gccatttacc gaaaaatttt gatcaattct atgggcggag
     7321 cgaatccgtt gaatcgtcat agtttgccgg atgtccattt ccgaacaacc gatgagatgc
     7381 taactgcatt tcacttttta ggggaagaaa cagcgaaaga gatcgtagta gaaaatacga
     7441 ataaaatcgc agatatctgc gaagaagtga ttccagtcaa agatgaactt tatacaccga
     7501 agattccagg ttcagaagat gaaatatcag aattgagtta cacaaaagca aaacaaatgt
     7561 acggagatcc gttacctgag atcattcaaa aacgattaaa aaaagagttg aattctatta
     7621 atggtaatgg cttctcggtt atttatctga tcgcccaaaa actagtgcat aaaagtaatg
     7681 aagatggcta tctagtaggt tcacgtggct ctgttggctc tagctttgtt gcgacgatga
     7741 caggaatcac tgaagttaat ccgttagccc ctcattatta ttgtccagag tgccaatatt
     7801 ccgagttttt tgaagatggt acgtatggtt ctggatttga catgccagaa aaacaatgtc
     7861 caaaatgtgg tgcacgctta aacaaagacg gtcatgatat tccatttgag acatttttag
     7921 gattccatgg agacaaagtg cccgatattg atttgaactt ctcaggtgat tatcaagcag
     7981 aagcccataa ctatacgaaa gtattgtttg gcgaagacta tgtttaccgt gccggaacga
     8041 ttggtacagt cgccgacaaa acagcatatg gctatgtaaa aggatacgaa agggacaata
     8101 atctgcagtt tcgaagtgca gaagtcgaca gattagcaaa aggcgctact ggagtcaaac
     8161 ggacaaccgg ccagcatcca ggggggatca tcgttattcc cgattatatg gatgtctatg
     8221 attttacgcc gatccaatat ccagcagacg atcaaaattc ggaatggaaa acgactcatt
     8281 ttgattttca ctcgattcac gataatgtat tgaaattaga tattctaggg catgatgacc
     8341 caactgttat tcggatgctt caagatttat cagggatcga tccacaaacg atccctacgg
     8401 atgacccgga agtgatgcgg atatttgccg gtcctgaagt acttggagta agtcaggaac
     8461 aaatttattc caaaacaggg acattaggta ttccagaatt cggcactcgt tttgttcgag
     8521 ggatgctaga agaaacgcat cctacaactt ttgcagaact actgcaaatt tccggactat
     8581 ctcatggtac agacgtatgg ttaggaaatg cggaagaatt gattcgacga ggagatgcga
     8641 cactggcgga agtaatcggc tgtcgtgatg atattatggt ttatttgatc catgctggat
     8701 tagatagcgg gatggcattt aaaatcatgg aaactgttcg taaaggacaa tggaacaaga
     8761 tccctgatga attgcgagaa acctatctat cggcgatgaa agaaaataat gtgcccgact
     8821 ggtatatcga ttcttgttca aaaatcaaat atatgtttcc gaaagcccat gctgcagctt
     8881 acgtattgat ggctcttcgt gtcgcttatt tcaaggttta tttccctatt ttgtattact
     8941 gtgcatactt ttctgtacgt gcagacgact ttgatctagt ctccatgtgc aaaggaaaag
     9001 atgctgtgaa acaagcaatg aaagaaatca cggacaaagg attagatgct tccgtaaaag
     9061 aaaagaatca actgacagtg ctggagttag ccaatgaaat gctggaacga ggattcaaat
     9121 ttggaatgat tgatttgtat aaatcggatg ccgttaactt tgttattgaa ggtgatacgt
     9181 tgatcgcacc atttagagct gtcccaagtt tgggaaccaa cgtggcaaaa caaatcgttg
     9241 aagcaagaaa agacggtcca tttttatcca aagaagatct tgccacccgc ggtaaagttt
     9301 caaaaacatt gatcgaatat atgaacgaca atggcgtatt gaaagatcta ccagatgaaa
     9361 atcaattatc gttattcgat atgctataag catctgtttt cctgtctgct tgtaatttta
     9421 agcagagtat ggtatagttc ttataggtaa tgatactaac tgtgagtgag cggatttttc
     9481 gctcactctt tttaatggaa ttacgcactt aattttttaa ggaggcgaaa cttttgagta
     9541 gcgtcgttga aacagtcaca gaaatggtga caccgatttt agatgaacaa aattttgaac
     9601 ttgtcgaagt cgaatttgta aaagaaggaa aaagctggtt cttacgagta tttattgaca
     9661 aagaaggcgg tatcgatatc gaagaatgcg cctttgtcag tgagaaactg agtgaaaaac
     9721 ttgatgcagc agatccagat ccgattcctc aagcttattt cctggaggta tcctccccgg
     9781 gagcagagcg gccattgaaa aaagaaagcg actatgaaaa ggcacttggt gattatgtcc
     9841 atgtctcctt ataccaacca gtagatggcg aaaaacaata tgaaggattt cttcaatcat
     9901 ttgatgctga acagcttaca ttgaaaatac gcataaaaac acgagaaaaa gaattgactt
     9961 ttgaccgaaa aaatattgca aaagctcgct tagctatcca attttaatca cggagaggaa
    10021 tcagaaaaaa tgagtaaaga aatgttaaat gcgttagacg ctttagaagc tgaaaaaggg
    10081 atctcaaaag aaatcgtgat cgatgcttta gaagcagcat tggtttctgc atacaaacgt
    10141 cactatggcc aagcacaaaa cgtcgaagtg gaatttgatc agaaaaaagg aaagatccat
    10201 gtctatgcgg taaaagaagt aacggaagaa gtgatggatt cacagttgga agtctcattg
    10261 aaagatgcac ttttaatcaa tccagcatat gagatcggtg atacgatccg ttttgaagta
    10321 acaccaaaag attttgggcg gatcgctgcg caaacggcta aacaagttat tttacagcgt
    10381 gtacgtgaag cagaaagaac gattatttat aacgaattca gtgcttatga aaaagacatc
    10441 atgcaaggaa tcgtcgaacg ccaggataaa cgttatattt atgtcaatct tggtaaaatt
    10501 gaggcagttc tttctaaaca agatcaaatg ccaaatgaat tttatcaacc acatgatcga
    10561 atcaaagttt atgtttcccg agtagaaaat acgtctaaag gtccgcaagt atttgttagc
    10621 cgcagccatc cagacctatt gcgccgctta tttgagcaag aagtaccaga agtctatgat
    10681 ggaatcgttg aaattgtcag catcgcccgt gaagctggcg atcgttcaaa agtggcagtt
    10741 cgctcaaatg atccaaatat cgatgcagtc ggtacatgtg tcgggccaaa gggacaacga
    10801 gttcaagcaa tcgtcaatga attaaaaggc gaaaacatgg atatcgtcga atggaatgaa
    10861 gatccagctg tattcattgc aaatgcattg aatcctgcac aagtcatgga tgtgatcttc
    10921 gatgagacaa atccaaaggc ctgcacagtt gtcgttccag actaccaatt atcgctagca
    10981 atcggtaaac gcggacaaaa cgcacgttta gctgctaaat tgactaacca taaaatcgat
    11041 atcaaatcag aatctgacat gacggaattt tatgaaaatc aagaacaaca aaaagaaaca
    11101 gaagaactgc atgatgaagc aatcgttcag tcagatttaa cagacgatga atatgaaaca
    11161 attgcattca acaatgaaac ggtcgaagaa aaaccagaag cttaacttta gtaaggaggc
    11221 aaagagatga aacaaaggaa aattccttta cgcaaatccg tggtttcagg tgaaatgaaa
    11281 cctaaaaaag agatggtccg aatcacccgt tcaaaagaag gggaagtatc gatcgatcca
    11341 actggaaaaa tgcctggacg aggagcgtat gtctcacttg agccggaaga agtacaacaa
    11401 gcttgggata aaaaaattct cgatcgagta ctcgaaacaa cattaacaga tgagttttat
    11461 caagaacttc ttgactatgt cactcaccaa aaagcacgta aagagttatt tggaaaatga
    11521 atacagttaa tcggcaaaaa gccatgaatc tcatcggtct agcgatgcgc gcgggaaaac
    11581 taatcacggg tgaagaactg accattgctg aaatccgcaa acaaaaagca aaattggtgt
    11641 ttgtggcaac cgatgcaagc gagaatacaa gaaaaaagat aaaagataag agttcatatt
    11701 atgaagttcc ttgctttgag ctattttctg aagcagaaat cacgcagatg atcggaaaac
    11761 ctcgcaaggt attcggaata atggatgccg gatttgcgaa gaagaccaag gagctaattg
    11821 aaggttagga aggtgattgc atgggcaaca aaagaatcta tgaattagca aaagaactca
    11881 aaaaatctag taaagacgtc gtggaaaaag cacaacaact tggcatcgat gtgaaaaacc
    11941 atatgggtgc gattactagc aatgatgaga agaaattgca acaagcgttc aaaaacccaa
    12001 gcacgaaaca acaagctgca caacaagcaa gcagaaaacc agccaatcaa cagccgaacg
    12061 atcaacgtaa aaaagaaaca acgaacaatc aacaaaaaaa taaaaataac cgcagttatc
    12121 aagatcgcgg tcaagggagc ggtcaagtga atcaaggaaa aaaaccaaca acaaaccaaa
    12181 ataatacggg aaataccagc agccaaaatc gtcaaggaac gagccaaggc ggcaatcaaa
    12241 accgtactaa caataacaac aaaccaaaca ataacaatcg cggcaaattt aataataata
    12301 accgtaatcg ttataataaa aaaggtaaaa aaggcaaaca gcaacaatca actaaaccag
    12361 ctgtaccacc acgcaaattc cgtgaattgc cagatgtatt agagtatact gaaggtatga
    12421 acgtagcaga tattgcgaaa aaaattcatc gtgagccagc agaaatcatt aaaaaattat
    12481 ttatgcttgg tgtcatggtc aatcaaaacc aagcactgga taaagatacg attgaactgt
    12541 tagcgacgga ctatggcatg gaaccacaag aaaaagtcca agttgacatt gctgatatcg
    12601 ataaattctt cgaggcagaa gaagtcgatc cagataaatt agtctcacgt ccgccagtcg
    12661 taacgattat gggacacgta gaccatggga aaacaacttt attggataca ttacgccatt
    12721 cacgtgtaac aagcggcgaa gccggcggaa tcacacagca tatcggtgcc taccagatcg
    12781 atattgatgg taaaccaatc actttcttgg atacaccagg acatgcggcc tttacaagta
    12841 tgcgtgcacg tggagcaagt atcacagata tcacgatctt agttgttgct gcagatgatg
    12901 gcgtcatgcc acaaacagtt gaagcaatca accatgccaa agctgcaggc gttccaatca
    12961 tcgtcgctgt aaataaaatt gataaaccag gtgcaaaccc tcaacatgtt atgcaagaat
    13021 taagtgagta tgagttaatt cctgaagcat ggggtggaga aacgatcttt gttgagatct
    13081 cagcgaaatt cggccaaaac atcgaagaat tgctggaaat gatcctgtta gtcgcagaag
    13141 tagaagattt aaaagcagat ccaacacaac gcgcaatcgg aacagtgatc gaagcacgtc
    13201 ttgataaagg taaaggtcct gtgtcaacct tacttgtcca agaaggaaca cttcatgttg
    13261 gtgacccaat cgttgtcggt aatacttacg gacgtgtccg tgtaatgaca aacgatcttg
    13321 gccgtcgcga taaagaagca ggacctgcaa cgccagtaga aatcactggc ttgaatgatg
    13381 tacctcaagc aggtgaccgt ttcgtagtct tcgaagacga aaagacagca cgtgcagcgg
    13441 gtgaagaacg cgcgaaacgt gcattattag aaaaccgtgc tgccacaagc cgtgtgactt
    13501 tggataactt atttgaaagc ctgaaagaag gcgaattgaa agaagttaac gtaatcatca
    13561 aagcagatgt acaaggttca gcagaagcac tggctgcatc attgaagaag attgatgtgg
    13621 aaggtgtccg tgtaaaaatc gtccattcag ctgtcggagc aatcaatgaa agtgatgtaa
    13681 ccttagcagc agccagcaac gctattatca tcggtttcaa cgttcgtcct acaccgcagg
    13741 caaaagtgca agctgatact gaagaagtcg atattcgtct tcaccgtatc atctataaag
    13801 ccatcgaaga aatcgaaact gcgatgaaag ggatgctaga ccctgaattt gaagaaaaaa
    13861 tcaccggtca aatgatcgtt cgtgaaacct tcaaagtttc taaagttggt acgattgcag
    13921 gtgcctatgt aacagaagga tatattcgta gagatagcgg tgtccgtgta atccgtgacg
    13981 gaatcgtaat ctatgaaggc caacttacaa gtctgaaacg attcaaagat gacgtgaaag
    14041 aagtcaaaat gggttatgaa tgtggtgcaa tgattgaaaa attcaatgac atcaaagtag
    14101 atgacgtaat tgaaggattt atcatggaag aagtcaaaaa tgactaaaaa ctgataaaag
    14161 gaggccaatc attatggcta actaccgtga ccgccgagtc ggtcaagaaa tcttaaaaga
    14221 agtcaatgat attttgcgca aaaaggtccg tgaccctcgt gtggagaacg taacgatcac
    14281 agatgtgaaa gttacggggg acttacagca agcaacgatc tattacagca ttttatctga
    14341 cttagcatca gataagaaaa cagcacaaga tggattgaat aaagcatcag gattgattcg
    14401 tcgagagtta gggcacaatc taagtattta taagacacct gaattgttct ttgaacttga
    14461 tgaatcagtt gtctatggca accatatcga tgaattgctt cgcgacttga acaaagacta
    14521 atcaaaaact cccgcaaatc ctgtgaaa
//
LOCUS       DAFEIE010000065        14238 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFEIE010000065
VERSION     DAFEIE010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.068"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP345_002216"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP345_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBL1760986.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP345_002217"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP345_002217"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBL1760987.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="LP345_002218"
     CDS             complement(2169..2906)
                     /locus_tag="LP345_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL1760988.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="LP345_002219"
     CDS             complement(2997..3524)
                     /locus_tag="LP345_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760989.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="LP345_002220"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="LP345_002220"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBL1760990.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="LP345_002221"
     CDS             complement(4401..4886)
                     /locus_tag="LP345_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBL1760991.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="LP345_002222"
     CDS             complement(5039..5236)
                     /locus_tag="LP345_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760992.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP345_002223"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP345_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBL1760993.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP345_002224"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP345_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBL1760994.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="LP345_002225"
     CDS             9211..9423
                     /locus_tag="LP345_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBL1760995.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="LP345_002226"
     CDS             9425..11104
                     /locus_tag="LP345_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL1760996.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(11358..11558)
                     /locus_tag="LP345_002227"
     CDS             complement(11358..11558)
                     /locus_tag="LP345_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1760997.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(11708..11869)
                     /locus_tag="LP345_002228"
                     /pseudo
     CDS             complement(11708..11869)
                     /locus_tag="LP345_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            complement(12249..12322)
                     /locus_tag="LP345_002229"
     tRNA            complement(12249..12322)
                     /locus_tag="LP345_002229"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12286..12288),aa:Ile,seq:cat)
     gene            complement(12634..13032)
                     /locus_tag="LP345_002230"
     CDS             complement(12634..13032)
                     /locus_tag="LP345_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760998.1"
                     /translation="MDKGNSVTFALENISLNKIHFELTDNFSYGDLEFNIELGYKEDE
                     AEYLEKKLVSLRAHIVGGMEGAPVDILLFSVIRVSTNEQPYKKLVEESMGELAKPILN
                     KASNLISNLYSEVGVMPTVIDLYQLYSQQK"
     gene            complement(13025..13477)
                     /locus_tag="LP345_002231"
     CDS             complement(13025..13477)
                     /locus_tag="LP345_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1760999.1"
                     /translation="MKSINDLLKKHPDLYKKLNSEQRNLSKQLLKIRLKKQKNVTEFS
                     KMLGISEKKYLEFEFGDMHIPVAEYNKLLKQVENLSYKDSMNFTIKVAGGPIKYDRIE
                     NKPYIRNKSYSVFKSRKRKEVSSNMVYASVNYQDTSRYIVEKEVYVHG"
     gene            complement(13464..13970)
                     /locus_tag="LP345_002232"
     CDS             complement(13464..13970)
                     /locus_tag="LP345_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761000.1"
                     /translation="MDIKWLVQQNDSNLELAIKYLEETIFEDEHLTDNFLQVLKYLEI
                     YSVKKNKLIGENDSPIKTPIELSLRNRMGILQRSEIVKELFYHKFSYEIRLDDTYEHY
                     RIVFFVYNSIEDATATTALTFGFTKNGTINSDKTRQAATESDDICKKVCNGEENYWIG
                     EEKLNEIY"
     gene            14075..>14238
                     /locus_tag="LP345_002233"
     CDS             14075..>14238
                     /locus_tag="LP345_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1761001.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTG"
BASE COUNT         4211 a         2989 c         2399 g         4639 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacctgc cacaagagaa attgtctctt
    11281 gtggcaggta tttttgttac tcgctttgtt ctctcgtaaa aattgatgtc taccatcaat
    11341 ttgatttaca gataaaatta agcttttaca acgtttgcag cttgtgggcc gcggtctgat
    11401 tcttcaacgt cgaaagtcac tgcttgacct tcttctaatg ttttgaatcc gtcaccttgg
    11461 atagctgaga agtgaacgaa tacgtcgctt ccatcttcac gtgagataaa tccaaatcct
    11521 ttttcagcgt tgaaccattt tactgttccg ttttccataa taatatcctc ctcgtgccaa
    11581 aagcactaat ttaaattgta acattgctcg tgtacgatag aggtgcaaca gatgtttcaa
    11641 cttctattcc caaacaaaat tacaatataa ttgtacactt gcttcatttt ttttgcaaga
    11701 aagcaactta cttctcttcc atcattcctt cttctctcaa actaaaatat cgtttgcgtc
    11761 cgatgatcaa gtggtccagt acagtgatcc ccatcatttc tccacacttt tgtatccttt
    11821 tggtaaaatt catatcctgc tgcgatggaa taacattacc agaaggataa tataggttag
    11881 tacacgtata aaaatatctt ttatattgac acaatttatt taacaagtat aataataatt
    11941 gaaagtgaat ttaaacaaat atacaccata aacacaacgt acctgcgaat acgttgtgtt
    12001 tttttctttt tcaaaaaaag acgcttaccg ctgcgaaaca gtaagcgcca ttgtcggctc
    12061 taatgtttat ctagccaatg actaaataat gccaaagtta aaccaattaa caatggcaag
    12121 agcacgtgct ccaaagtgaa ttcaaacaaa tcatacacct cctcccacga aaatctctgt
    12181 ggaagcgacg agccgacatt ttattatacc attattgaat tttatttttt atcaaataga
    12241 ttaaattatg taccctgtag gactcgaacc tacgaccgga cggttatgag ccgtctgctc
    12301 tgaccaactg agctaagagt acaggttgtt gccacataaa gccataaaca atcaaccagt
    12361 agaaggtgtg gcaacaatcc tgttatcgca tagcttggag tgtgactatt atgggtgata
    12421 gtgaagatat gcgataacat cactatttta tcgaatgatt tttatagttg tcaatacagt
    12481 catctaaata cttcatatca atcatttatt cagaaacaaa ctatcttgca ggatctatac
    12541 gagttaatta cagagcaaaa aagcctcaac caaggatgac tggttgaggt ctttgtcttg
    12601 caaatttaaa tagataactc tattacttgt attttatttt tgttgactat atagctgata
    12661 taaatcaata actgtaggca taactcctac ttcgctatat aaattagaaa tcaaattaga
    12721 agctttattc aggataggtt tagctagctc tcccatagat tcttctacta attttttata
    12781 tggctgttca tttgtagaaa cacgaataac tgaaaagagt aaaatatcta ccggtgctcc
    12841 ttccatcccc cctacaatgt gagctcgtaa agaaacaagt tttttttcta gatactctgc
    12901 ttcgtcttct ttatatccaa gttcaatatt aaactctaaa tctccataac taaaattatc
    12961 agttaattca aaatgaattt tattcaaact aatattttca agtgcaaaag taacactatt
    13021 tcctttatcc atgtacatat acctcttttt ctacaatata gcggctcgta tcttggtaat
    13081 taacactagc atagaccata tttgacgata cttcttttct ctttctactt ttaaatactg
    13141 agtaactttt attccgaata taaggtttat tttcaatacg gtcatattta atagggccgc
    13201 cagcaacctt aatagtgaaa ttcattgaat ctttatagga caaattttca acttgtttca
    13261 aaagtttatt gtactctgca acaggaatat gcatatctcc gaactcaaat tcaagatatt
    13321 ttttttcact tattcctaac atttttgaga attctgtcac gtttttttgt ttttttaatc
    13381 ttattttaag taattgtttg gacaggtttc tttgttcaga atttaatttt ttatataaat
    13441 caggatgttt ttttaataaa tcattaatag atttcattca acttttcctc ccctatccag
    13501 taattctctt ccccattgca tactttctta catatatcat cactttctgt agcagcttga
    13561 cgggttttat ccgaattgat tgttccattt ttcgtaaaac cgaatgttaa tgcagtagtc
    13621 gcagtagcat cttctataga attgtatacg aaaaaaacaa ttctataatg ctcataagta
    13681 tcatctagtc ttatttcata actaaattta tgataaaaaa gttcttttac tatttccgat
    13741 ctttggagta ttcccatccg atttcttaag cttagctcaa taggtgtttt tattggagaa
    13801 tcattttcac caattaattt atttttttta acagagtaaa tttcaagata ttttaatact
    13861 tgtaaaaaat tatctgtaag atgttcatct tcaaagatag tttcttcgag atatttaatc
    13921 gccaattcta aattgctatc attttgttga accaaccact taatgtccat ctcactaaac
    13981 gagagtgtaa aatattttgt gtaaatagaa aaaaggaagt cccttctgta gaatagagtt
    14041 accacaacac attcacagaa aagaggactt ccatatgaac gattttacta cagaaattct
    14101 aaagactcta gcgaacaaag gcgatttgaa tgaattattc cgtgtccatt tggaaaaagc
    14161 tgtcaatacg cttctcaaaa cggagttaac ggctttcctc gattacgaaa agtacgatcg
    14221 cattggtttt aacacggg
//
LOCUS       DAFEIE010000066        13872 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFEIE010000066
VERSION     DAFEIE010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.069"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(163..2160)
                     /gene="tkt"
                     /locus_tag="LP345_002234"
     CDS             complement(163..2160)
                     /gene="tkt"
                     /locus_tag="LP345_002234"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL1761002.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2262..2513)
                     /locus_tag="LP345_002235"
     CDS             complement(2262..2513)
                     /locus_tag="LP345_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBL1761003.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2660..3283
                     /gene="lexA"
                     /locus_tag="LP345_002236"
     CDS             2660..3283
                     /gene="lexA"
                     /locus_tag="LP345_002236"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBL1761004.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3463..3681
                     /locus_tag="LP345_002237"
     CDS             3463..3681
                     /locus_tag="LP345_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761005.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3970..4482)
                     /locus_tag="LP345_002238"
     CDS             complement(3970..4482)
                     /locus_tag="LP345_002238"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBL1761006.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="LP345_002239"
     CDS             complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="LP345_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBL1761007.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6935..7378)
                     /locus_tag="LP345_002240"
     CDS             complement(6935..7378)
                     /locus_tag="LP345_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBL1761008.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7379..8167)
                     /locus_tag="LP345_002241"
     CDS             complement(7379..8167)
                     /locus_tag="LP345_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1761009.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8164..9105)
                     /locus_tag="LP345_002242"
     CDS             complement(8164..9105)
                     /locus_tag="LP345_002242"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBL1761010.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9282..9869)
                     /locus_tag="LP345_002243"
     CDS             complement(9282..9869)
                     /locus_tag="LP345_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBL1761011.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="LP345_002244"
     CDS             complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="LP345_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBL1761012.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11691..12701
                     /gene="gap"
                     /locus_tag="LP345_002245"
     CDS             11691..12701
                     /gene="gap"
                     /locus_tag="LP345_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL1761013.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12786..13721)
                     /locus_tag="LP345_002246"
     CDS             complement(12786..13721)
                     /locus_tag="LP345_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1761014.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3835 a         3103 c         2445 g         4489 t
ORIGIN      
        1 tctcaagaaa cacaaactaa tccgaagaat tctttgtttt gtcatttaaa tgtaacatag
       61 ccgaaaacga aaagtaatat tgatttattc ttctaacaca taaagaacag ctgtctccaa
      121 cttgcagaca gctgttctta tcagtcaaac aattgcttgg atctatgata gttgattgta
      181 cgtattcacg acattttcta ctgtaaatcc aaattcttct aaaattttag tgccaggggc
      241 agatgcaccg aaatgatcga ttgtaatcgt tgcgccctct gttcctacgt agcgttccca
      301 tccaaatgat gcagcagctt cgatagccac acgtttcttc actgatttag gaagtacact
      361 ttctttatat tcagaagatt gtttttcaaa gaggtcaaag cttggcatag aaacaacaga
      421 aacatctttg cctttttcag ccaattcttt ttgagctttc acagccaaat caacttcaga
      481 acctgttgca atcaaaatac cttctggtgt ttctccttgt gatggagaaa gaacatacgc
      541 gccttttttc accatttcat ctgctacttc ttttgtagaa ggcaatactg gaaggttttg
      601 acgactcaat acaaggatag taggcgcatc tgttgtctcc atcgctactt tccaagcagc
      661 acgtgtttca tttccgtctg ccggacgaat cacttgaaca ccaggcatgc agcgaacaga
      721 tgctagttgt tcaatcggtt cgtgcgttgg tccgtcttct ccgacagcaa ccgagtcatg
      781 tgttaagacg taaacaacag gagtatgttg gattgctgct aaacgaactg ctggtcttag
      841 ataatcgaca aagacaaaga atgttccacc gtagatacga gttccgccat gaagttggat
      901 accattcata gccgaagcca ttgcaaattc gcggacaccg aaccagatgt tgcgtccttc
      961 ataatgttca ggagtgaaat ctttatctgc agccaccatt gtattattgg aacctgacaa
     1021 gtccgctgaa ccaccccaga agcttggtat agctttcgat aattcttgga tgacttcttt
     1081 acttgaaaca cggcttgctt gactgcttcc aacttcataa gttggcaatt ctgcatccca
     1141 gttttctggt agtttgccat caaaagcatc ttcaaattgt tgtgctaatt caggataagc
     1201 ttttttataa ttggcaaaca tttcattcca tgcatcttca gctttttgtc cttcttctat
     1261 catcgtttga tggaagcggg cagctacttc ttctggaaca gtgaaatctg gatactccca
     1321 accataaact tctttagcca tcttgatgcc atcttcacca agaggagcac catgaacagc
     1381 agatgttcct tctttaggag caccatagcc gatgactgtt tttacttcga tcaatgttgg
     1441 tttgtctgtt tcagcttttg cttcttcaat cgctttagag attgcttcta ggtcatttcc
     1501 gtctttcact aagatatgtt gccagccata tgcttcatag cgagcaccaa cgttttctgt
     1561 gaaagctttt gaagttggac cgtctagtga aatatcgttt gaatcgtata aaacgatcaa
     1621 tttccctagt ttcatatgac ctgccatcga acttgcttct tgagataccc cttccatcaa
     1681 gtctccgtca ccgcatattg catacgtata gtgatccatc acattaaagt tttctttgtt
     1741 atacgttgct gcaaggtgcg cttctgccat tgccataccg acagccattg caatcccttg
     1801 tcctaatggc cctgtagtgg cttctacacc atctgtatga tgtacttcag gatgtcctgg
     1861 tgttttagaa tcccattgac ggaattgttt caaatcatcg attgtcactt gatagccagc
     1921 taaatgaagc aagctataca acattgctga cccatgtcct gccgaaagaa cgaaacggtc
     1981 gcggtcagcc cagttttttg atgtcgttgg atttactttc aggtgttttg tccataacgc
     2041 atatgccata ggtgctgcgc ccatcggcaa tccaggatgt cctgagtttg ctttttggac
     2101 tgcttcaata cttaatgtac gaattgtgtt aacgccaagt tggtcaattt tgtcaaacaa
     2161 aataacccct cctattaatt taggtttttt ttacctttat ttcttacact ttcattctat
     2221 aagatgtcac acgaaaaagc aatctttttc agtatttttt actaaaagtt gtcatttcgg
     2281 ttgtgtaagc cttttttctt ttggatttct tttaattttt ccggggtcac gtcattgccc
     2341 tcaggatcga cgactttcat tccttcgata tgatgacgca taccggaacg aaaagcttcc
     2401 aaatactctt tgcgcaagtt gatttgttct tgttcttcgg cttttgagag accattttcc
     2461 ttctttttac gtgcaagttc attgatccgc tctatttttt caggtgacag catgctcagc
     2521 cctcctttta ctctccttca tattatataa aaactgaaaa aaaaacaact agataaacta
     2581 aataaaatac gaacattcgt ttgatttagc gctttttata tggtactatt tatttatcaa
     2641 gtgaaagaag gtgtaccttg tggcccgaca aactgaatca agacaaatcg aagtcttacg
     2701 atatatccat gaacaagtaa cccaaaaagg atacccgccg actgtccgtg aaatcgggga
     2761 agctgttcag ctttcttcta cttctactgt tcacggtcat cttgcacggc ttgaaaaaaa
     2821 agggtttatc caaagagatc cgacgaaacc tcgtgcaatc gagttgacaa aacaaggttt
     2881 agaaaagatt gggattcgtc caacaactat tccagtactt ggcgtcgtaa cagctggaga
     2941 acccatttta gcagtagagg atgcttcaga cttctttcca atccctccta atctttcttc
     3001 cgaagaaggc agtctcttta tgctgacaat tcgtggagat agtatgatca atgctgggat
     3061 attggatggt gacaacgtga tcgttcggaa gcaagaaact gctcaaaatg gcgatattgt
     3121 cattgcaatg actgccgagg acgaagcgac ttgcaaacga ttctataaag aaaaaaactt
     3181 tttccgtctg cagcctgaaa acgacttgct cgaaccaatc atcttagatc aagtatctat
     3241 attaggacga gtagtaggac tttatcgtag tcatatctat taattgctac taattaaaag
     3301 aaaacttttt aaaaagagtt tgagacgttg gtctcaaact cttttttcgc ccgggttctt
     3361 cttctttcaa atttttatca cttccctctt tacaaaccga acaaatattc gtatactaaa
     3421 tatacgaaca attgttcgca taaattaaag aggtgagaat tcatgaaatc aatgagacgt
     3481 cttggcttag tattaactgt tttgttttta ggtattatta ttggtaattt cggcatacgt
     3541 ccagctttac ttgtgtttgt tccgttattt actttgtggt tcatgttgtg ggatgaaaag
     3601 aagtaccgtc aatctgagcg gcgcagaatt catgaagatc atttctatca tgagccctac
     3661 tacagatcca ggcaatcata ataaggattg actgctaatt attcaaaaga caagaagtta
     3721 aacttttacg ggggtgtgac aaaaatcggt cacatccttt ttttcgaata aacggtgttc
     3781 taaagccagt ttttcggtat taagtcaaat tgcggaaaaa gtgatttttt aaacttctac
     3841 tggtctttgc ttgtttccat ttataaaaaa atagcgaccc tcaaaagtca gatagagaat
     3901 ctgacttttg agggtcgctt taaaatcgct tctttaagaa taacatcaag aatagcttct
     3961 tttttctgct taatattcca ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc
     4021 atggagatcc atcaattcga tcaaaaatgc gcagcctacg actacaccgc ctaattgttc
     4081 gatcagttcg atcgtcgctt tgattgttcc tccagtagct agcaaatcgt cacaaatcag
     4141 cacacgttga cctggtttaa tggcatcctt atgcaatgtc aatgtatctg ttccatattc
     4201 taatccataa gtcacttcga tggtttctcg aggtaacttc ccttttttgc ggactggggc
     4261 aaaaccgact cctaactcat aagcaacagg acatcctacg atgaatccac gggcttctgg
     4321 cccaactacc atatcaattc gtttttcttt tgcataattt acgatttgtt tagtagcttc
     4381 ccgataagcg tcaccatctg ccatcagtgg ggaaatatct cgaaacacaa ttccttttga
     4441 cggatagtcg ggaatactgg caatataatc ttttaaatcc actctttgtt tcctcctagg
     4501 ttgttaacca tttctttatg gtaggaatat cgctcaaaag caaaaattcc tcaactttga
     4561 ttttattgag ccgtcgctgg tataatctgc tctcagtcaa aggatgactt tctgggctag
     4621 cgactttttg taaaacaccg ttctctattg taacaaattt caattcaaaa aacacctgta
     4681 tcataaaaat taataatttt tcagggatac gcaaatattg agctattgct tttattttat
     4741 gacgtatatc aattcgttct tgagaatgga tcaatttaaa caattttgcg tactgttctc
     4801 ttgtgcctac cccattcaaa taggcctcat caggtgaaat ccccatcaga taaacacgat
     4861 tgaatgaata agaccgaaaa acttctttca gatccgctaa atcatctgga caatccataa
     4921 caactagaga gtttggtttt cttttttcaa ttattgcctt tacagaatct agtccttcga
     4981 aaacaatcgc agcttcctgg ataatctcag gcacgaattt caacgtcgaa gaatcaaatg
     5041 ctaaataaag gctaccttcc gacgttcggc tctgttcacg gaaacgtttt gcccgccaat
     5101 caaatacttg cagaccaccc acagaaaaat cagataccat cagctgcggt ttcttacgcc
     5161 cgttccattc attgatcgaa agctttccta ccacatctac ctgattattc agcagttctt
     5221 cttcttgagt accaaaacca aaagcgaccg catcaagctg actcgatgca tcggaaagga
     5281 caaatttcag atgctgttgg tttgctccga ttcttttgat attttctgct tggacttgtc
     5341 gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg cgccaatagt ttcagctcat
     5401 caattcgctc tactgttact tcatttggca gcaatacttc atcaattctc aactcaggcc
     5461 ctctcatcaa gtcaatttga tgatcgacta tatattggtt catcttctcc tgtagtatag
     5521 tgacattttc acttggcatc gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa
     5581 ataaatctcg catctggtca agcatttcaa aaagattcaa ggcttcaata ctacgtccag
     5641 atcctttagc tgatccatct tcttttaaag taaggacaag cgttggttta cccgtttcat
     5701 tcattatttt cccagcaaca atgcccaaaa cgccttcatg ccatcctcgg tttaccaata
     5761 gatggatatg attctcctta ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga
     5821 ttgcttttct ttcttcattg atctcattca atttttttgc ttgaacggat gcttcctctt
     5881 catcaaacgt cgcaagtaac gagacggcag gacgtggatc gcccatccga ccgattgcat
     5941 ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc
     6001 cgctttcttc aaatagcgcc tgaagtccta tccgttctga atgatgaatg gcatcgattc
     6061 ctaatgaaac aaggattcga ttctcatcag tcaatgaaac taaatcggcg atcgttccta
     6121 tcgctactaa atccaaaaat tctgcaggcg gttcttccaa taatgcagaa gctactttga
     6181 atgctactcc gactcctgcc aaatctggaa atggatagtg ccccgctgga tgacgagggt
     6241 gaacaatcgc ataagcgtct ggtaaattct caggtagttc gtgatgatct gtaatgatca
     6301 cgtctacacc agcttgctga gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa
     6361 cagtgatgat caactggatt ccttcttcga tcttttcttg gtataccgat tggtttggtc
     6421 catacccatg ctcaaatcga tttggcagga atacttctac ttctgcacca agtaattcca
     6481 gtgtttcttt cattaccgtt gcactggtga tcccatctgc gtcataatca ccgtaaacga
     6541 ggattttttc tccactgatt acagcttctt ggattcggct gattgcttta tccatatcgt
     6601 gtatcagata cggatcatgt aattcttgtt cctttggatg taaaaatcgg ttgatatcct
     6661 tttcctcatg gtaacctctt tgccacagta acttaccgac aaatggagat aatttcagtt
     6721 cacggatcat ttggagaaag gattcagaag gctctgtctc gcttaacttc caatcaaaat
     6781 ttgcttgtct cactttctca ctcctaactt agttattata gcaaaggaaa tcagcaaaaa
     6841 aaagcagaaa gaaagaataa aaacagatca gatccgctag acagatgttc agcaggacct
     6901 gatcttttgt acgaccattt atgaaatatc cctattagtc aaaataattg aagctttgtt
     6961 tgggcgattg agttttttgt tcttccggcg ctttcaattg actgatttgt gcggttttcg
     7021 cttgtaactc cgcctgataa gcagcttcca actccgcacg ttcgtttcta aactcgcgtt
     7081 gctgttcttc ttttgcttct tcaattttct tttgaagttc tgtttgatat tctgacattt
     7141 cctgagtcag ctgtttgatt tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa
     7201 atacaatcag tgcaccaatc agcgcagaac cgatgatcac taagatcaat ggcgcagaaa
     7261 aggaagtgaa gccaaaactt acaggaacat ttttattgtt caatacagca aaaagaacaa
     7321 taatcaaaac taaaacaaat ccaagaatca cattgctttg ctttttcaat tccttcacct
     7381 actttttgtt aaaaattccg ctggctaaat aatcaccaat cgttggaaac agcgtataaa
     7441 attttgatgc aacttctaaa ataaacggtt gattgatttc ccgttttgga tgtctcatat
     7501 tgcggacgat catttttgcc aacttggcag gttctaaaac gatttgtccg actttttcca
     7561 aatagcttcc gcttggatca gccttatcga agaaatttgt ctcgattgga cctggattca
     7621 ctgtcgtaac agctacgcca agtggtttca attctaatcg caaagcgttg gagaagccaa
     7681 ggactgcaaa tttcgtggca gaataaaccg ttgattttgc agttgccatt tttccagcca
     7741 tagaggcgat attaatgata tgaccttgtc ttctttctgc catatcgatc gcaaattttt
     7801 gtgtcaaaac catcattcct aagatgttga cttcaaacat atcgtatgct tttccaaggt
     7861 cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt gtttaccaga atatcgacgc
     7921 gcccgacttc ttccatcacc ttttcatata attcgtccac gctttcagga ttgctgacgt
     7981 ctaccttgaa agcataagcc tctttgccgc tcaagcgtct gcactcgtct ctgacacctt
     8041 ctacaaatgc cattcttcgt gcgcaactta taacgattgc tccttgcttt gctgcttcat
     8101 aacagatttg tgcgcccaga ccgcctgaac tacctgttac taaaacaact ttatcttcta
     8161 aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg ctatcaaaat ctttcataat
     8221 cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc tctaaagctg cttttcctaa
     8281 atatctcgca ctgatatgag taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc
     8341 agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc attcttgctt catctttatt
     8401 aaatgtgctt tcatgtacca gaatatcgct attttccgca agcacaacgg aattatgtgt
     8461 ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt ttatctggac ctacgaaatc
     8521 ttttccattg atcgtccgcc catcttctag ttggatcgtt tcaccttgct tcagtttgcc
     8581 gtacagtggt ccagctggaa tacctaattc ttttagacga tccacctgca attctccttt
     8641 atgatcatgt tcaaccacac gataaccaaa actgtcgatc ccatgattta gtttttttgt
     8701 ataaacagaa aattgctgat cagtaaaaat cggggctgtt tcatttagct caatgaattt
     8761 cagcggataa cttaaacgcg tttgcgaaat acctaaagag acttttatgt attcctctat
     8821 cccttttggc ccgtaaatct ctaatggcgt atccccacct tgaaatgacc ggctgctgat
     8881 gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt gtaatgaaaa ttttaccgat
     8941 ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa
     9001 caaccaaact tcattgcgct cgtctaaaag tttcaatgct atacttgtca catttctatg
     9061 ttttgcagga acacctgcac ctgttcctaa aaattgtaat tccataatct acctgacttt
     9121 ctttaagttc ctctttaatt ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa
     9181 tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt ttctttgaaa attactataa
     9241 aaacagcagc gaacccgttt gagatcctct gctgtttttt attaatttga agatccagaa
     9301 ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct
     9361 ttcgcatgat tttcagcttc tttcgcatca tgcacatctt tttcgacatc ttcataatcc
     9421 aagcgagtaa tttctccgcc taattccatc attaccaatt gattcagtgg gcgattgtcc
     9481 tcttcatcag caatcaagat cagtcctgta gctccttcac cgattttatt tcctacaaag
     9541 tcgaacacgg tctgggcatc ttttatttct ttggcatctt gtgtcgcacc gatcattcct
     9601 ccggcaaacc atcctaataa aatccctagc ggaccaccta atacaccaac caacattccg
     9661 attaatccac ccgtagaaga tttgttatta ccggtaaagt cgataaaatc ttctattttg
     9721 aattgatgtg tcccattagg atcatggctg acaactgcca tctgttctcc tttaatcgaa
     9781 cgaacagcat gtaacttttt gatttctgaa aatgcctgat atgcctggct ttctacttga
     9841 aaatttaaaa tgattactcg tttgctcatt aaaaacgccc ctttcatacc ttcttgttat
     9901 ttattttacc tttaattgaa aaataagaaa agaaaagcac tctttttttc caataaaata
     9961 gggctgtgac aaaagtcgta tcacagctcc tttttccgaa taaacggcgt tcttgaagct
    10021 gatcacttct gtcacaacct cccttaaatc tgaatctata ttttttggta tttgttttta
    10081 tttgcttgcc tattcgacaa attcaaattc aaactcaccg atacgtacaa ggtcgccatc
    10141 tttcgcaccg cgtgcccgaa gagcttcatc cacacccata ccacgtaatt gacgagcaaa
    10201 acgcatcact gtttcatcat gatcgaaatt cgtcatttgg aataattttt cgatcttctc
    10261 accagataag atccacgttg catctgaatc acgatcgatt tggaactcag gaccttctgg
    10321 attgaatcca tagtgtacag tttcttcttc cagttcttct tcgtacaatg ggaattctgg
    10381 cgttacttct aacaaatctg ctgtagcatt caataacgcg tccaatcctt gtcgagtcac
    10441 tccagaaatt ggaaatactg ggatgtcatc agcaaattca tcttcttttt ccttgttcag
    10501 ctgttctttg aatttcacta gattttccgg tgcatccggc atatccattt tgtttgccac
    10561 gatgatttgc ggacgctcta gcaagcgtaa gttataagta gataattctt tgttgatggc
    10621 aagatagtct tcataaggat ctcgtccttc catcccactc atatcgatca catgtaaaat
    10681 tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc
    10741 tccttcaatc aagcctggca agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac
    10801 cattcctaga ttaggtacga gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga
    10861 tgaaataacg gatagtaaag tcgatttccc gacagatgga aaacctacaa gtccaacgtc
    10921 tgccaatact ttcaattcta gttcgatttt tcgctcttgt cctggttcac cgttttcagc
    10981 aatttccggt gcaggattcc gaggagaggc aaaacggata ttccctcgtc caccgcgtcc
    11041 accttttgcc acaactagtg tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt
    11101 ctccgcatct cggacagtgg ttccttgtgg tactttaaca taggtatctt ctgaaccacg
    11161 accgtgcatc cctttactca tcccattttc acctggctgc gctttgaaat ggcgattgaa
    11221 ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc aagatgacat cgccgccacg
    11281 accaccgtct ccgccagccg gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac
    11341 cattccgtct ccgcccttgc cagctttcac atcgatcgtt acttgatcta aaaacatgga
    11401 cataattaag tcctcctatt attcatttat ttatttgact gcctgaattt ccacaataaa
    11461 caaaagtctt acttatttta tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga
    11521 ttgtttacct tcttcttttt ttatcatttg gtaaggtttc caaccttttt tctgctacca
    11581 agtataattt tttgacaaaa tattctttgc gtagcagaat aacagtgtat taattgtatt
    11641 aattgaggat gccgtttcac agcaccccta ataaaggagg aacttttgat atgacagtaa
    11701 aagtaggtat taacggattt gggcgtattg gccgtctggc tttccgccgc atcaaagaag
    11761 tctcagatga tattgaagta gtagcaatca acgacttaac aagtccaact atgttagcac
    11821 aattattgca atttgactct actcatggta cttatcctgg cacagttact gcaacagaag
    11881 actcaatcgt agtggatggc gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa
    11941 tcccttgggc aaaagaaaac ggtgtagata tcgtactaga atgtactggt ttttatacat
    12001 ctgaagaaaa agcaaaagcg catttagatg ctggtgtcaa acgagtagtt atttctgccc
    12061 cagctggtgc tatgaaaacc atcgtctata acgtcaatga tgatacatta gatgaaaacg
    12121 acaaaatcat ctcagcaggt tcatgtacaa caaactgttt agcacctatg gcttatttct
    12181 taaataatga atttgggatc gaagttggta caatgacaac agttcatgcc tacacttcca
    12241 cacaaatgct cttagatgga cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg
    12301 ctgacaatac tatcccacat tctactggtg ctgcgaaagc aatcggctta gttatccctg
    12361 agctacaagg aaaattacaa ggacacgcac aacgtgttcc agtcgttgat ggttcattaa
    12421 ctgaattggt ttcagtattg aaaacaaaag taactgctga tcaagtaaac gaagcaatca
    12481 aaaaacacac agttgacaat ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg
    12541 atgtcattgg aacaactcaa ggttcgatct ttgacccaac gcaaacagaa gtaacaactg
    12601 ctggtgattt ccaacttgtt aaaactgttg catggtatga caatgagtat ggatttactt
    12661 gccaaatgat tcgcttacta gaaaaattcg ctaacttgta atttgataga tcaatcgata
    12721 aaagaagcct ttgactggat ccagtcaaag gcttctttct tttcatcccc tacttttaaa
    12781 ctcgttcaat gaacatattg gcttaaaaat tgttggacta cttgctgata tttttcagga
    12841 tctgtcttgt atgcttccgc atgctcggct ccttttacaa catacttttc ttttggtccc
    12901 ttcgttgcac gatagacctt atctaacatt tcaaatggta caaatgtatc ttcgtctcca
    12961 tgtataaaga gcattgggcg ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg
    13021 aaaaagtagc cagcacggac ttttgtcact agactcgtta cttgcataag cggaaatgct
    13081 ggaagactaa acatatcgtc tagctgataa gcaagctcat catgaacgga agaataaccg
    13141 caatcttcaa tgattgcttt cacattatct ggtagttttt ctccgctagt catcataact
    13201 gttgctgctc ccatgctgac accgtataga acgatttctt gcgattttcc attgttttct
    13261 agcactttgt ttatccactg tacatagtct ttacgctctg gccatccaaa tccaatgtaa
    13321 tccccttcgc tttttccatg tcctcttgca tcaggaacaa ggacattgta acccatatca
    13381 tgaaacatct ttgcgtaatt ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca
    13441 agagctgttt tttcactttt cgtttcagca ggaagataaa tcgctgataa tttcagaccg
    13501 tcttttgaag tgatggtcca atcgcttcgg ttttcttttg aactaaacca tttatgtgca
    13561 tccgtttctt tggatgtctg tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca
    13621 gaaggcacaa cagcataatt ataaaaataa ttccctgcaa acactaacgc aacaatcaga
    13681 gctaaagcga cgcctaaaag gattttcatc caaagtttca taaatcatcc atctcatttc
    13741 tcttttttca tataaccttg aattagtata atcaaagaat ctctactatg caatgttcat
    13801 ttttataacc cgcgaattgt aaaattaagt tagaaaaata aaaaggcatt tatggtacac
    13861 tcaaattgta tt
//
LOCUS       DAFEIE010000067        13427 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFEIE010000067
VERSION     DAFEIE010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.070"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..912)
                     /locus_tag="LP345_002247"
     CDS             complement(<1..912)
                     /locus_tag="LP345_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBL1761015.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1340..1903
                     /gene="efp"
                     /locus_tag="LP345_002248"
     CDS             1340..1903
                     /gene="efp"
                     /locus_tag="LP345_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBL1761016.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2004..2174
                     /locus_tag="LP345_002249"
     CDS             2004..2174
                     /locus_tag="LP345_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761017.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2389..3648
                     /gene="lysA"
                     /locus_tag="LP345_002250"
     CDS             2389..3648
                     /gene="lysA"
                     /locus_tag="LP345_002250"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBL1761018.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3635..4435
                     /gene="dapF"
                     /locus_tag="LP345_002251"
     CDS             3635..4435
                     /gene="dapF"
                     /locus_tag="LP345_002251"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBL1761019.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4438..5319
                     /locus_tag="LP345_002252"
     CDS             4438..5319
                     /locus_tag="LP345_002252"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBL1761020.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5316..6032
                     /locus_tag="LP345_002253"
     CDS             5316..6032
                     /locus_tag="LP345_002253"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBL1761021.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6038..6733
                     /gene="dapD"
                     /locus_tag="LP345_002254"
     CDS             6038..6733
                     /gene="dapD"
                     /locus_tag="LP345_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBL1761022.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6749..7750
                     /locus_tag="LP345_002255"
     CDS             6749..7750
                     /locus_tag="LP345_002255"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBL1761023.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEKPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7747..9108
                     /locus_tag="LP345_002256"
     CDS             7747..9108
                     /locus_tag="LP345_002256"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBL1761024.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9068..10219
                     /locus_tag="LP345_002257"
     CDS             9068..10219
                     /locus_tag="LP345_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBL1761025.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10194..11363
                     /locus_tag="LP345_002258"
     CDS             10194..11363
                     /locus_tag="LP345_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1761026.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11538..12917
                     /locus_tag="LP345_002259"
     CDS             11538..12917
                     /locus_tag="LP345_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1761027.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13198..13427
                     /locus_tag="LP345_002260"
                     /pseudo
     CDS             13198..13427
                     /locus_tag="LP345_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4483 a         2339 c         2923 g         3682 t
ORIGIN      
        1 gtaaatgttt tttgataaat agcggtctgc tgcgtctgga aaaatcgtaa cgacacgatg
       61 accaggtggt aaacgacgaa tttctcttaa tgctgctgca aaagccgcac cactcgaact
      121 tccaactaat agtccttgtt ctcgtgctaa ctgcctagta tagttaaacc cttctacatc
      181 agagattgtc tcgatctgat tgattgaaag gggagaaaga aacggcggaa tgaattctac
      241 accgataccc tcaatttcgt gaggggctgg atcaccacca tttaacacag agccctctgg
      301 ttctacaccg attattcgaa tgtcgggata tttttctttc aaaaaggtag aagttccagc
      361 aaaggttcca ccactcccaa ttcctgctac aaaactatgg atattttctt tgatttcatg
      421 aaagatttct ggccctaacg tatgatagta agcagcagga ttatctttat tttcaaattg
      481 aagaggcaga tagctgtttg atatctcctc tgcaagtttt ttacttttgc tgatggcacc
      541 gatgattcct tgctcactag gagaatggat gatctttgct cccaatgctt tcatcaattg
      601 ttgtttttct aagctaaact tctctggaac aacaaaaacc gttcttaatt tgtatgtgag
      661 tgcggccaga gcgatcccaa ttcctgtatt tccggcagtt ggttcgatga tcgtcgtttt
      721 ttcattgatt tttccttggg caaatccttc tttgatcaaa taactgccca atctatcttt
      781 gatacttcct ccaggattta aatattctag ttttgcataa atagcagaac ctttaggcat
      841 agaatagtgc tgattgtcaa agcgataaag cggtgtggaa ccaatagctt ctgtaattgt
      901 cgagataatc atgtgggcct cctaaaaaaa gataataaaa aaaggagctg actattaaat
      961 cagctccttg aaagacatag agaaaaattg agtagataaa aagataagtt acctggtact
     1021 cattctatga agggcaatta atagacatga caaatagtat gctgctttta tgcaccatac
     1081 aacagcaacg attcaattgt ttttggttgc tgactgtcat gtgtatccct ccaagtaaaa
     1141 tttttattaa cgatagcatg aaaaaaaata aaagtcaaag gcttgaaaga aaaaaatatt
     1201 tcgatagcat cgtttacccg tgtttatttt tctgacaaat aggcatgaga ccttaaaaga
     1261 tagagaatac tctagttttc tggccggttg tctgatacaa taaagttgat tatgataaag
     1321 aaaagaagga gcaaaaataa tgatctcagc aagtgattta agagccggta tgactttcgt
     1381 acaagacggc aaactgatta aagttctgga tgcaagccac cataaacctg gtaaaggaaa
     1441 tacagttatg cgtatgaaac tgaaagatgt ccgttcaggt gcaacatacg acacaacgtt
     1501 cagaccagaa gaaaaatttg aaaaagcaca tatcgacaca aaacctgtac aatatttgta
     1561 cacgatggat gatacagctt tcttcatgga tttggaaaca tatgagcaat atgaaattcc
     1621 tgtagaaaca gtagaagaag aaatgaaata tatcctagaa aacatggaag taaaaatcca
     1681 atttttcggt agcgaagtca tcggcgttca attaccaaca actgtcgtat tacgtgttgt
     1741 ggaaacacaa ccttccatca aaggtgcaac agtcactggt tcaggtaagc cagcgacaat
     1801 ggaaactggc ttagtagtca atgttcctga cttcatcgaa acagatgaat tgttggaaat
     1861 caatacagca gaaggttctt atgtaaaacg tgcgtcaaaa taattcgcta acggattgat
     1921 aagaatttga aaacagagct tgacctcttg aaaggcagat catcggatct gcctttcaag
     1981 aggttttttg tggaatcagc aaattgaaaa ataaaaaagt atttgatttt atttatattt
     2041 tgaaagatga atggcaaaag ctagagaaag aaaaaactgc acttatttat gaagaaattg
     2101 aaatgattca taaaattgaa aatatccgaa ctattccgaa ctatattgaa gcgaaaatat
     2161 tttttcatca ctaaatagtg ttgaatttat gtttttatgt ataaatagct tctaatagtt
     2221 cgggtatttt gtttttataa ccatttttat tcttattttt aaaaaaatat ttcgaaatat
     2281 actagacaat tcagaaaatt ttgtttaata ttattccaat aaaattcaaa tctttatcaa
     2341 atgaaattcc aataaaaacg gaaaaaaagt gaaaagagga atgaaaaaat gacagaattg
     2401 ataattggcg gagtcacagc aagcacattg gcagaaaagt ataagacacc tctgtatgtg
     2461 tatgatgaag aaaagatgag acaaacgatg ctgtcattca agcgaggctt tgtatcgaaa
     2521 cgttttgata caaaagtgct ttacgcctct aaagcattcc aaacgattga gatgctgcat
     2581 ttagttcgtg aatatggatt cgggctagat gttgtcagtg gtggggaaat ctataccgct
     2641 ttgcaagctg attttcctag agatactatc tacttccatg gtaacaacaa gacgccagag
     2701 gaactgatct atgcacttga aaatgatttg ttgcatattg ttgccgataa tttgatggaa
     2761 gttgaattat tagcagaatt aagccaacgc tatttaaaaa aaatctgtat catgcttcgg
     2821 ttgaatgtcg gagtagaagc acatactcat gaatatatcg tcactgcgca tattgattca
     2881 aaattcggca tgagctatga aagtaaagag tgccaacaag cccttcagtt gataaaagaa
     2941 agcagctatc tagagttaga aggatttcat gctcatatcg ggtcacaaat ttttgatgtt
     3001 actgcttggt tagctgaaat cgacaaattg acgaattact taaccgattt tgaccaacct
     3061 ctttccttga atcttggcgg agggtttggg attcgttata cacaaaatga tcagccgatc
     3121 ccagtcgaag aggcactaaa aaaactgatt gaatatacgg aagaagcttt ggaaaaacga
     3181 aaactgacca ttcgtcaatt actgatcgaa ccgggtagaa gtattgttgg agaagctggt
     3241 acaacactat acacgattgg tttcatcaaa aagacaccac ataaaaaata ttactttgta
     3301 gatggcggga tgacagataa tatccgtcca gctctgtatc aggcagaata cgattgtgat
     3361 ttagcagcaa aactgtcgga agaaaaaaca gagaaagtga cgattgcagg aaaaatgtgt
     3421 gaatcaggcg atgtggtaat taaagaagct tatttgccga aagcagaatc gggtgatctt
     3481 ttagctgttt attccacggg agcttatgga tactcgatga gcagcaacta caatcgagcg
     3541 acacgaccag cagttgtttt tgtcaataat ggccaatcaa gactgattgt tcgcagacaa
     3601 gcattttctg atctactaag gggggaagtt tcctatgatc cttcataaat ataatggctg
     3661 cggaaatgat tttatcttat tagattacgc agaagacaca gattatagtc aattagccgc
     3721 ttctttatgc acaaaagaaa aatatgatat agacggattg atcgccgtaa aaatcgatcc
     3781 gttggaaatg atctattaca acaaagatgg cagccgcgcg ccgatgtgcg gaaatggcat
     3841 tcgctgtttt gctcgatacg taaatgatca gaacatgatg aatgaacagg aattcaacgt
     3901 agagacatta gcaggcacaa gaaaaattac ggtgttggat ccctcacctt tttattgcag
     3961 cgtagatatg ggagtgccag atgattctcc ggaaaaaatc aaagctaatc aaacttatcc
     4021 aataaaaaac caggaaatag agatcaatgg tgaaaaagta acgatcacta gtttattttt
     4081 aggaacgatt cataccgttg tttttgttga aaatgcgcgt gaggaagtct ggagaaaaag
     4141 aggtgaactg atctgtcatc atcctttgtt caaagaaaaa accaatgtca actttgtaga
     4201 agtagtcaat gaacaagaat tgatcgtccg tacctatgaa agaggagtag gttggacact
     4261 tgcttgcggt acaggttgct gtgcctctta tgtggttgct aaggaaactg ggaaaatttc
     4321 agcagatcag gtagttgttc acttggaaca aggagacttg atgatctctg gtgaggatgc
     4381 gatacaaatg gctggcccag cagttcatga atggacaaga atattggagg aatgaagatg
     4441 ataaaaggtt cgatcgtggc gctgatcacg ccgatgaatg aagagggatc agtagattat
     4501 gctggtttgg aaaaattgat ccaattccat ttagatgaac aaacagatgg attattagtt
     4561 ttaggtacaa caggagaatc ttctacgctc acacaatctg aggaggagca gatccttcaa
     4621 ctgacagtaa agaaagtggc tggccgtgtg ccggtgattg caggagctgg aacgaataat
     4681 acgaaagaaa cgattgaaaa agcgaagcat tttgcttctt tgggggcaga cgcacttttg
     4741 gtcatcaccc cttactacaa caaaacaagt gatgcaggac tagctgctca ttttacagca
     4801 attgcagaag cctcaccgat tccgcttatt ttgtataatg ttccttctag aacaggcatg
     4861 tcgattccaa tccatgtatt agtaaattta gcagaacatc ctaatatcat tggtttgaaa
     4921 gaagcctcag gagatatggc ttatgtgatg gatgccgctc ggttgattgg agaagaattc
     4981 ttcctttaca gtggaaatga tgatttgatc ctaccagtaa tgagtgtagg aggaagcggt
     5041 gtaataagtg tatgggcgaa tatccaacct aaaatagtcc atgaattagt aaaagatacg
     5101 caggacggaa gatggcagca agcaaaagaa aagcaattaa atgcacttga actgatccat
     5161 gccttgttca gtgagaccaa tcctattcct gtcaaagcag ccatgtcatt attagactta
     5221 ccttccggac ctctacgcct gcctttagtt tctctttcaa aagagaaaaa gaaacaatta
     5281 gctcagcttt tgttaaaaga aaggacggtt gaaaaatgaa aatcggactg attggcagtg
     5341 gacagatggg aaatagagtc gaagaagttg cacaagaaag aggagatacg gtccttcttt
     5401 tacggacggc acctaaagaa gcaactacgc ttgcttttac ggaactgcca gaactgctta
     5461 ttgatttttc tcatccagat aatttagaga aaatcctttc gtatagctta tcatatcaac
     5521 ttccgttagt cattggcacg acaggttata cacaatcaca gttccaagaa ataaaagaac
     5581 atgccaaaca tgtacctgtg atgtatagtg ctaatttttc gttcggcatc atggtgatga
     5641 atcaactaat caagcaagca gctgcaatgt tgcaaggctg gcagatcgaa ctgattgaaa
     5701 aacatcatag tcgtaaaaaa gatgcaccat ctggtactgc aaatatgctg cttcaaacaa
     5761 tccaagaagt gcaaaagctg cagcccgtat acaactggca agggaaaaaa agagaagaaa
     5821 accaaattgg tgtacacagt attcgtgcag gttctttacc tggtgaacat gatgtattgt
     5881 ttgctgctac tgatgaaata tttacgatca aacatgaatc tttttctaat cgaatctttg
     5941 ctgcaggcgc agtagaagca gcggactggt tgaaagatca gtcaccaggt tattacaaat
     6001 tagaagattt attaatggac aaaggggtgt aaaaaacgtg gaagctcaag aaatcatccg
     6061 ctacattcaa acggcatcta aaaagacgcc tgtgaaagtc tatctgaatg taaccgagcc
     6121 aatcgaattt aaagaaagta aagtttttgg tgaaggaagc agcttcgttg tttttggtga
     6181 ctatgagacg attgctccgg ttttagaagc tgaatcagaa aaaatcattg aaatcgaaat
     6241 cgaaactgct gcaagataca gcgcagttcc tttgctagat attaaaaaaa ttaatgctcg
     6301 tatcgaacca ggtgctatta tcagagatca agtgtcaatc ggcaacaatg ccgtgatcat
     6361 gatgggagcg attatcaata ttggtgcagt aatcggtgaa aacacgatga ttgatatggg
     6421 tgctgtctta ggtggacgag cgacagtggg caaaaactgc catattggtg caggagctgt
     6481 cttagcaggt gtgatcgaac cagcatcggc caaaccggtt atcgtagaag acggcgtact
     6541 ggtaggtgcg aatgcagtga ttgttgaagg tgtccatatc ggaaaagatg cagtcgtggc
     6601 agcaggagca gtggttttag aagatgtggc agcagaaact gttgtcggtg gaatacctgc
     6661 acgtgtatta aaaataagtg atgatcagac aaaagaaaat acagcattga ttgctgcgtt
     6721 acgcgaatta tagaggagat ggagaaaaat gcgcgaaata gatacctgta ttgtgggggc
     6781 aaccggatta gtcggccaaa cgatgctcaa agtgttagaa gaatatgatt ttccagtagg
     6841 acgattgaaa ttattagctt caaaacgttc agccggtaaa gtttgtgtat tcaagaaaaa
     6901 gaaacacact gtacaggaat tgacagaaac ttcatttgaa ggatatgatt tagcgctatt
     6961 ttctgcaggt gcttctgtat ccaaagagtt tgcgccaatc gcacgaagtc agggactatt
     7021 tgtcatagat aattcctcag catggcggga agattcggat attccattaa tcgttccaga
     7081 ggtcaatctg gaagactata cattgaatcg gctgattgca aatccaaatt gttcaaccat
     7141 tcaagcggta cttccgctta aagctttaca agaagccttt ggtatccagc gagtcaatta
     7201 ttcgacctat caagcagttt ctggttccgg gcaaaaaggc attgaagatc ttcatcgtac
     7261 gcaaaatgac gagaaaccag ttttgtatcc ttataatatt agccaaacgg tgattccgga
     7321 aatcgatcag cctttggaaa atgggtatac aaaagaagaa cagaaaatga taaatgagac
     7381 ccgtaagatt ctgcatcagc ctgctttgcc agtatcagca acctgcgtac gtgtgccaat
     7441 cgaaaatgga catggagtct ctgtggcagt tcaactgcaa aaagagttta cgacggaaga
     7501 aattagagag tgtctcagcc agtttccagg gattcaatta gaagatgatc tagcagcaca
     7561 taaatatccg acgagcattc ttgctagagg aacagatatg gtttatgttg ggaggatcag
     7621 aaaagacact tctttagaga acggattgtt gttctatacg actgccgata acatacgcaa
     7681 aggagccgct gcgaatgccg tacagattgc tgcagcttta atgcagaaaa tagcggaggt
     7741 ggcaagatga gtaatacgct gaaagtagcg aaattcggcg gaacatcgat gtctcatgaa
     7801 gagcaattca aaaaagtccg tacaattgtt ctttcagatc ccaatcgcca agtgatcgtt
     7861 gtttctgctt taggcaaacg tacgtcagat gatgacaaag taacagactt actttatttg
     7921 atttatgctt accttcagca tcatgttgat tggacacccc tttggaaaag gatttgtgat
     7981 cgtttcattc aagtaagaga tgttcttgcc ctgcagttac ctattgaaga tgaactagca
     8041 cgcatacaga aacaactgga agacgaaaag ataactgaag attatttagt aagtagaggt
     8101 gaatatctga ctgctcaact gatggctgag tatcttggtt accagtttat tgacgcaaaa
     8161 gacctgattt tctttgacta tgatgggaaa atcgatcagg aaaaaacagc acaggaaatc
     8221 acaaaagcat ttaaaagata tccgaaaatg gttgttccag ggttttacgg ggcgaaccct
     8281 gcaggaaaag aaaaattatt gggccgtggg ggaagcgaca ttaccggcgc gatactggcg
     8341 aagatgttgc aagcggaaag ttatgagaat tggacggatg tttcaggaat catgatggct
     8401 gatccgcgaa tcatcgatca tcctaaaatc atcgaggaaa tctcttttag agaactgaga
     8461 gagatggctt atatgggggc taacgttctt catgaagcag ctgttttccc agttcaagag
     8521 gctgatatcc ccatccaaat aaaaaatacc aatgatcctt tcgctcaagg gacaaaaata
     8581 tcgaatcacg aaatagaaaa ggaaaatgga ctgacaggaa tagctggacg caaggatttt
     8641 ctttccatca ctttattcaa acgtcatatg tccgatgaaa tcgggtttat ctggaaagca
     8701 atgagcattt ttgctaaaca tgagatatca atcgaacata ttccttcagg gatcgacaat
     8761 atcggagtga tcgtctcagc agaagcgatt gccgataagt tatttctcat cacgaaagaa
     8821 ttaaaagaaa cacttggcgt ggaagaaatc gtcgtgatcg aagacttagc tttgatctct
     8881 gtcgttgggg gtccgcataa agaattgatt ggattatctg ggaaagtgtt atcgatattg
     8941 aacaaattag aaattcgcac atcgatctta tcacaaggag cacaggagtt gaatctgatc
     9001 atcggtgtac cgaataatca atatgaaaca gtagtgaagg gtatctatga agggatggtg
     9061 aatacggatg ctgaaagaat atcgaatggc actccatcaa attcctgaaa tcgggtttca
     9121 tgaattcaag acaaaaaaat atttatatga acaagtaaaa aacagcgagg ccgttatcca
     9181 tgaaatcggc gaaacaggac tactccttta ttttgataat cagcaagaag aaacgattgc
     9241 ttttcgaaca gatatcgatg cactgccagt caaagaagaa acgaatctct cttttgcttc
     9301 taagcatgaa ggttatatgc atgcatgtgg tcatgacgga catatggcga tgcttttagg
     9361 gttgactgac tttataacta aacacattga ggatcttatt tataatgtag tactgatcta
     9421 tcagccatca gaagaaattt ccggtggcgc acaaagcgtt attcagtcag gattgttgga
     9481 taaatatgaa gtacaagcaa tatttggctt tcatctatgg cctggactag ctaagggaga
     9541 agttttctct cgaccaggac ctttgatggc acaaagcagt gaaacagaca ttatcattaa
     9601 aggccagtct gcacatattg cttctagtga aaaaggaatc gatagtctgg aggcagctgt
     9661 acgatttttg aagaatgttt atgattttga ccggcaatta ccggcagagt ggaatcatct
     9721 aatgaaattt ggccaaatcc aaggtggaac gatccgaaat gttttagctg gagaagttat
     9781 tgtatccgga agtatccgtt cttacagttc agatatgcaa aattatttga agaggggatt
     9841 agaccattta gcagaacagt ttcactctac agctactatt tcttttcgct ataatgacgg
     9901 ctatccagct gtaatcaacc atagaggctt atatgcagca ctgttagatt caaacaaact
     9961 acatgaatta gatgctccag ttcttcaagc cgaagatttt ggcatatata cgcaacaata
    10021 tccatgtgta tttttctttt taggtgtcgg tgatacccct gctttacatg atccgacgtt
    10081 cgattttgat atggatgttt tagaaaatgg tgtagaatgg tacaaaacga ttctttttac
    10141 agaaaatctt cttgtaaaaa tcgatagcag ttcaaaagag gagcgagtaa ataatgatga
    10201 atttatccaa tcgatttagt cctaggcttt ctagaataga agtatcaaaa atacgacaat
    10261 tcgatcagca aatatcgtcg ataccagatg tgatcaaact caccctggga gaaccggatt
    10321 ttccaactcc tgaacatgtc aagcaagcag gaatagcagc gattgaagaa gacttttctc
    10381 actataccgg aatgagagga ttagaggaac tgcgggaagc ggcttgtata tttcagcaac
    10441 agcgttatgg attaacttat gatccgcaaa cggaagtttt gacgacagtt ggtgcaacgg
    10501 aagcgattgc ctctgcgttg ttatctgttt tggaagaagg agacaaggtt cttattccag
    10561 cgcctgctta ttcaggatat cagccattag tggaactagc tggtgctgaa ttgatcccga
    10621 tagatacttc tgacacaggg tttgtctgtc agccggaaca atttgaacga gcatttgaac
    10681 aatatggatc agctgtcaaa gcagtcattt taaactatcc taacaatcct actgggacga
    10741 cattgtctgc aaaacaattg aaagcaatcg ctgaggtttt aaaaaaatat ccggtatttg
    10801 ttataagtga tgaagtatat gctgaattga cttatagtgg aacgcatatg tccatagcta
    10861 cttatcttcc agaacaaaca atcgtgataa gcgggttatc caagtcacat gcgatgactg
    10921 gttggcgagt gggctttatt tttgctcaaa aagcccttat tgacgaacta attaaagtcc
    10981 atcaatatct ggtgactgcc gctacaacga tgtcgcaaaa agctgcggct gaagcgctaa
    11041 taaatggggt gaaagatagc gagaatatga aagagcaata tcaaacacga agagactatc
    11101 tggtccagca attggcgcct ttaggatttg aagtgaccca gccaaacggt gcattttact
    11161 tgttttgcaa actcccagct gccattcaaa ctgactcttg gcagttttgt gtagaattag
    11221 cggaacaggc aaaagttgcg tgtatcccag gaattgcatt tggcccagaa ggagaaggtt
    11281 atatccggat ttcttatgct agcagcatgg aaaaattaca tgaggcctgc aaacggatca
    11341 aagacttttt aacagaacag tgattcatag attttatcaa aaaaacaatc gttaattttg
    11401 cggtatattc tgcaaggaga cgattgtttt ttaaatttag ttcaaatgaa cgcgtttctt
    11461 ttgattcata actaatgtaa tgttaagttt aaattgttta gaatgatttt aaaagaatat
    11521 tcaaggaggt ttcatcaatg gaaaaaatca aagttgtcat tgtaggtgca tctcatggag
    11581 ggcatcaatc gatcttggaa ctattgacac gatacggtga aaatgtagat atcacgctat
    11641 ttgaagcagg agactatatt tccttcatgt catgtggtat ggagctgtat ttagaagaca
    11701 aggtaacaga tgtaaatgat gtacgtaatt tcagaccaga aaactttccg caatccaatg
    11761 ttcatatttt aaataatcac gaagtaaaaa cgatcgatgc cgataaaaaa acagtaacgg
    11821 ttactagcgc atcagataac gaaacaaaag aatatcctta tgacaaattg attttgagtt
    11881 ctggtgtcaa accaaacaat ctgccagtac caggagcaga tctagaaaat gtctacttga
    11941 tgcgtggata caattgggca accaaaatca aagaaaaatt aaatgatccg gctattaaaa
    12001 aaatcgctgt cgtaggtgcg ggttacattg ggatcgaagc agcagaagca agccgaaaag
    12061 ctgggaaaga agtcgtattg cttgatgtga tcgatagacc tttaggcact tatttagatg
    12121 ctgagatgac agatatttta gaacaacacc taaatgaaaa cggtattgaa gttttgacaa
    12181 atgcaaaaat cgaagctttt actggtaacg gaaaagttga ggcaatcaaa acaagtgaaa
    12241 aagaaatccc agcagatcta gtcattcaag ctgccggtgt gaaggcaaat acagaatggt
    12301 taaaagggat cgtcgactta gatgaacgtg gctggatcca aacaaatgaa tacttgcaaa
    12361 cgaatcttcc agatgtgtat gcagtaggag atgctacact tgcttattct atcccagcac
    12421 gcaaaaaaat gccgatcgct ttagcgactg ttgcacgtag agaagcacgt tatgtagtaa
    12481 aacatctttt tgaagaagta ccaaacaaac cgttcggcgg agtcgtaggt tcctctgcat
    12541 taagtgtctt tgactatcat tttgcagcaa gcggattgaa tagctttaca gcagcaaaag
    12601 caggagtaga tgtacgagtg tcttattatg aagatacgtt acgaccaaaa tatgtaccag
    12661 aagaacaagg aaatccaaaa gtgtccatcc aattattctc ggatccaatg acccatcaat
    12721 tgctaggagg agcagtatta tctacctatg atgttacagg tcaaggaaat gtattggcac
    12781 tagcgatcca aaacaaactg actttagaag aactagcaga agctgacttc ttcttccagc
    12841 caggctttga ccgacaatgg agcatgttga atctagccgc tcaacaagcg ttaggagaag
    12901 aaccatttgt agaataagaa aacgaaatat ttgaaaagag gttgtgaaaa agctgccttg
    12961 catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttaac ttggctggac
    13021 ttattaccgc agatgcaagc ttttgaacac cgtttatttt caaaaaaggg actgtgacac
    13081 gatttgtgta ccgaccccca aaagttagac caaaaaatct aacttttgga ggtcggtatt
    13141 ttttatggtt aaatatactt ttgaacttaa attaaagatc gttcatgatt atttggatgg
    13201 caaaggcgat tggaccgtaa aaatccagat caagagattg aagcggaaat gcttaaaatt
    13261 cgggagaagc acaaggatta tggctgttta cggatgacca atgaactaag aaaccgcggt
    13321 ttctctatca ataaaaagaa agttcagcgc ttgatcaaga agctaggaat aaaagtaacg
    13381 gcatacacgc gtaaatcacg tcgctacaat tcttatcgag gaaaagt
//
LOCUS       DAFEIE010000068        13346 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFEIE010000068
VERSION     DAFEIE010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.071"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(45..1364)
                     /locus_tag="LP345_002261"
     CDS             complement(45..1364)
                     /locus_tag="LP345_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1761028.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="LP345_002262"
     CDS             complement(1361..2014)
                     /locus_tag="LP345_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1761029.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="LP345_002263"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="LP345_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="LP345_002264"
     CDS             complement(2724..3440)
                     /locus_tag="LP345_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBL1761030.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3564..3749)
                     /locus_tag="LP345_002265"
     CDS             complement(3564..3749)
                     /locus_tag="LP345_002265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761031.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            3976..5249
                     /locus_tag="LP345_002266"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="LP345_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="LP345_002267"
     CDS             complement(5356..6387)
                     /locus_tag="LP345_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1761032.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="LP345_002268"
     CDS             complement(6394..7224)
                     /locus_tag="LP345_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1761033.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="LP345_002269"
     CDS             complement(7221..8036)
                     /locus_tag="LP345_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1761034.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="LP345_002270"
     CDS             complement(8033..8857)
                     /locus_tag="LP345_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBL1761035.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="LP345_002271"
     CDS             complement(8847..9947)
                     /locus_tag="LP345_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1761036.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCVSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="LP345_002272"
     CDS             10125..10910
                     /locus_tag="LP345_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBL1761037.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="LP345_002273"
     CDS             10943..11326
                     /locus_tag="LP345_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL1761038.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="LP345_002274"
     CDS             11402..11533
                     /locus_tag="LP345_002274"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1761039.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="LP345_002275"
     CDS             11502..11738
                     /locus_tag="LP345_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1761040.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11816..12787)
                     /locus_tag="LP345_002276"
     CDS             complement(11816..12787)
                     /locus_tag="LP345_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBL1761041.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4055 a         2911 c         2306 g         4074 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacgtcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atgtcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagacgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttat
//
LOCUS       DAFEIE010000069        13241 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFEIE010000069
VERSION     DAFEIE010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.072"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(94..2193)
                     /locus_tag="LP345_002277"
     CDS             complement(94..2193)
                     /locus_tag="LP345_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL1761042.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(2413..3522)
                     /gene="rpoD"
                     /locus_tag="LP345_002278"
     CDS             complement(2413..3522)
                     /gene="rpoD"
                     /locus_tag="LP345_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBL1761043.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(3546..5387)
                     /locus_tag="LP345_002279"
     CDS             complement(3546..5387)
                     /locus_tag="LP345_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBL1761044.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(5569..7884)
                     /locus_tag="LP345_002280"
     CDS             complement(5569..7884)
                     /locus_tag="LP345_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1761045.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(8069..8929)
                     /locus_tag="LP345_002281"
     CDS             complement(8069..8929)
                     /locus_tag="LP345_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBL1761046.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(8988..9509)
                     /locus_tag="LP345_002282"
     CDS             complement(8988..9509)
                     /locus_tag="LP345_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBL1761047.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            9787..10548
                     /locus_tag="LP345_002283"
     CDS             9787..10548
                     /locus_tag="LP345_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1761048.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            10574..13165
                     /gene="mprF"
                     /locus_tag="LP345_002284"
     CDS             10574..13165
                     /gene="mprF"
                     /locus_tag="LP345_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL1761049.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSAFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
BASE COUNT         3572 a         2759 c         2333 g         4577 t
ORIGIN      
        1 aaaaaggagt atgacaacag ttgtgtcata ctcccctttt tcgaataaac ggtgttaaac
       61 ggcaggctca cagcctcttt catttgccta aaattaattg ctcccatttc ctccgaacca
      121 tccagtttta cagttgatgg ttacgatgta aaatggcaaa gcactttctc caatgccttt
      181 catcaatgca gattttgttg aagtggcata tagattataa tagccttccc cattttcgat
      241 tctggctttt tctaatctgt aacctccttc aacgatatat ccacgttgga tacatgtagc
      301 aatcactttg ctttggacac ctggtgccca cgtccatgct ggattagatg catcggcaat
      361 atcacttgct ctggcagatt tgattggctg attcgctgag tttgaagagg aaggggtcga
      421 ggatgccgct tcttgctgtg ctgcttgtgc gaccgcagct tgttgagcgg cttgagctgc
      481 agctgctgct tgagcggctt gttttgcttg ttcttcagct gcttttttcg cttcttctgc
      541 ttttttcttt tcctcttctt cttttttctc tttatcagtg agcatcttat ctacttgttt
      601 caattgttca ttcaactgag cagatagatc tgtatttttc actttttcta ctgcttcttt
      661 tgccgtcttg tattggtcgc gtgttgctga atccactact tttccgtctt taaagactat
      721 agctgttttt tctttagctg tttgcaattc agcatattga tttttagctt ctgtttgtgc
      781 ttgttgaatc aattttccaa aatctgtgtt atccgtttcg attgcttgga tctctttatc
      841 tgctttcaac ttgatgtcat ctgctagatg atcatcgacg atggcaggtg ctatgaacca
      901 ctcattcact ttttggatat ctcggatctt agattggata tcttggtaag ttgtttctaa
      961 ctctgaatat cctttttcat tcttaagact ggataaatca ttttttagtt ttgataaatc
     1021 ttgatgaatc atatctgcac gaataaattg atggtgatca tctgtataaa aggcagcaag
     1081 tttctcatga agttcttcca tttgttgctg tctttttgct tctgctgcta cttcggcttc
     1141 tactttttga tgatggtcat aataagccca gcttcctcca ccgagtagaa gtactgctgc
     1201 taaaacgaga taaggtactt tttttgattt tttcttttgc gctttatctg gatctgtttt
     1261 ttctaagttt gattcttgat gtgttttttc agtatctggc acgattgtta ttgatttcgc
     1321 ttctgcttca aacagcttag gctggttctc ttctttttct atttttgctt caagatcagt
     1381 accctctttg cttacagatt gattttcagc atcggattca ctatttattt catcgggctc
     1441 tgttgacttt ttgtctgtgt tttcgagtat ttcttttttc tctgcttccg gcagtttatt
     1501 cgttttttcc ttttctaatt gtttttcagt aaatacttca gttttttctg tgatatccgt
     1561 ttttacgtct tttattttta ctgtttcttt acctgtggcg ttttctctat cagagtcttt
     1621 ttcagtttct tgttcctttt ctggctctac tttgttttcc tgtgcaattt tttcactgat
     1681 cattttgagc agctctttcg cgtgctcttc ttttgtatct tcacgatgtg ctttgatata
     1741 agcggatagt atcgaatttt cttcctcatt atcgacgatt tctttcagtt cagctactct
     1801 tcttttttgt tttgattcaa gcgtttcttc ttgattcttt cctgattctt ccgaagtctc
     1861 atgaacagtt gctttcttct gttcattttt ctctatatta gttacttgat cgtgagcagg
     1921 tggttcttcg tcttctggtt ctgctttttc gaataattcc attacagatt ctagaggtaa
     1981 atctttcaat tccgaccatt cgattggatc gtttaattct gtatcaggaa agactgcatc
     2041 ttcagttgat ttatcctgca tagctgcatc tgtatttgtt tcttcaattg attcttttat
     2101 ttgctgatct tctgcagtta tttgatgacc gcagtctgga cagatagtat tctgctccat
     2161 ttttttcgat ccgcaatttg gacatttttt catcacttag cgatcggctc ctttactagg
     2221 tttacgctac catttaatct atcatattct atacgtcacg ccaatagctt atttttagga
     2281 tttacttaaa aataatgaat gaatttcctt cctatagaaa aaaaagcttg agactgcgta
     2341 gtctcaagct ttttttcttt taaaataaac caaacagttt tactgatttc tcttctggtc
     2401 aatagtccac gcttattcta agaaatcttt taattgtttt gaacgagaag gatggcgcaa
     2461 ttttcttaat gctttagcct cgatctgacg aatacgttcc cgagtaacac caaatacttt
     2521 ccctacttct tccaatgttc tcgtccggcc atcatctaaa ccaaaacgta agcgaaggac
     2581 attctcttcc cgatcagtca atgtatctag tacatcttcc aattgttctt ttagtaactc
     2641 ataagctgcg tgttctgctg gacttgttgc ttcctggtct tctatgaaat cacctaagtg
     2701 agagtcatct tcttcaccga ttggcgtttc aagggaaaca ggttcttgcg cgattttcaa
     2761 gatttctcgg actttttctg ttggaagatc catttccgca ccgatttctt ctggcgtagg
     2821 ttctcttcca aggtcttgca gcaattgacg ttggatacgt atcaatttat taattgtttc
     2881 aaccatatga actggaatac ggatcgtacg tgcttggtca gcgattgctc gagtgatggc
     2941 ttgacgaatc caccatgtag cataggttga aaacttaaat cctttgcggt agtcaaattt
     3001 ttcaactgcc ttcatcagtc ccatgtttcc ttcttggatc aagtcaagga actgcatgcc
     3061 tcgtcctaca taacgtttag cgatacttac tactaaacga aggtttgctt ctgccagacg
     3121 ctgtttcgct tcttggtcgc cttcttcgat tttcaatgct aacgctactt cttcttccgc
     3181 agttaaaagg gagacacggc caatttcttt cagatacata cgaaccgggt cattgatttt
     3241 tacaccggtt ggcgcagaaa gatcttctgt ttttgcttgt tcagcttttt tctcagcact
     3301 cttcaagctg tgaattgatg gatcaccatt ttcatccacc acactgatac ctgcgtcttc
     3361 aatcttttgg atcaatttgt ccatttcatc tgcattcaaa gtgaatggtg tagcaagctg
     3421 attggataaa tcatcatata caacttgtcg tttgggtttg ttttctttga tgaaagctgc
     3481 tactgctgct tcatacgttt ttttatctgt tccatttgcc ataaaagaag gccccccttg
     3541 agtagctatt tggcttgttt taactgtttc gttaaattga tgatttcaat cgtcaattca
     3601 agctcaagct gtttgtttcc agttcgtctg gcttcttgct gcatttgttt ttttaatgtt
     3661 atttcatcag ctaagccaga tttgctgatc acatctagca agtcttggat ttctcgtggc
     3721 gaactttctt ctgccaccgg taaatattcg atttccacca ccaaccgcct taaattttca
     3781 tcttgcaaaa agtctaaaaa ctctgcaagg ttgaattcat aatgttgtga gacatatgca
     3841 tcgaataaaa aataaacttc tgcatatgca tcatgaataa actgaaattc tcgttctttt
     3901 aaaatattac ggacagaaac ttctttaaat gcacgatata atagaatctg ctctgccttt
     3961 tctacttgcg tcaaaggtct ctttttccgt gcagtttctt gtctcgtaac ctgagtgtgt
     4021 tgactttcct gaggttcttg acgattttgc tgatttgtcc ttcgaagatc gcgcagttgt
     4081 ttttgtatcg tctctctgcc gatctgaaac tctgttgaca gttgagatag atacatatct
     4141 tgttcgattg gtgaaacaac tcggctaagt tcaactagta attcttcgag gtattcgatc
     4201 ttgtcttttt cattatctaa atttttccct tgttttaaat aacgtgattt aaaagtaaag
     4261 actgtttcgc gcccatgagc cactaattct tggaaagatg cttctccata cttacggaga
     4321 tattcatcag gatcaagctt ttctggaacg actacgacag aaagtgctaa tcgactgttt
     4381 tgccgaagca attcaatccc tcgattggtt gcttcaaaac ctgcgttgtc tccgtcatag
     4441 caaaagacca attctttcgt cagcttttcc atttgttgga tctgttgagc tgttagactt
     4501 gtccccatag aagctaatcc agttttgata ccagcctgcc atgcagcaat cacatccata
     4561 aacccttcga acaacaaaat ttctccgttt ttccggatat cgcttcttgc tttatcaaga
     4621 ttaaataaaa cttgtctttt attgaacagt tctgtttctg gactattcaa gtatttgggc
     4681 tgatcttttt cctgcccttt ttcaggtgca agccagcgtc ctgaaaaacc gatcgtctgg
     4741 ccttgagaat tacgaagtgg aaacatcact ctttgataaa aacgatcaga catacggcca
     4801 tcatcatgcg tgacaaacaa tccagagcgt tctaacaatt catttgaaat tgattcattc
     4861 ttgaatactt gctgaagaaa agaacgctca ttaggtgcaa aacctatgtt gaattcttca
     4921 attaattcta aagacaaccc acgactttgc aaatattcta aagctggctg tccagctttt
     4981 gtatgcaata gcatgtgatg atagatttcc gctgcttttt catgagcagc aatcagtttc
     5041 cccgtagcag attcaggatt ttggacagct atagtacgct gacgccattg atcttctaac
     5101 ggtatctgtt cgaagtctgc cacttttacc actgcttctg gaaaacttag accttctagt
     5161 tcttgaagaa aagtaaacac gtttccgcct ttaccacaac caaagcaatg aaaaatctgc
     5221 ttgtcttctg caacagaaaa agacggtgta cgttcttcat gaaaaggaca cagccccaag
     5281 taatttttac cagacttttt caactggaca tattgtccaa tcacctcaac gatattcgtt
     5341 tgactgcgta ctgtttcgat aacctcttga ggaatccgtt gagccatttt ttcaccccct
     5401 gctctattga tatcttttgg gtttaacaga agatatttca ggagaataac cggtaaaaaa
     5461 tcgcactaac tgaaatcagt gcgattttaa aggacacaat tatacatgtt tgattgtatc
     5521 atatttcatt gctttttcaa gtataacaca tttctatctc attaagcatc aatttgctac
     5581 tcttttcagt aactgatttt gaatatcagc cttccagtac aatactcgaa gaacaatatt
     5641 tacgagcatg aatacaaaga agtatcctac gctctctccc aaccctaagt ttacttccaa
     5701 aattccatgg aacagcattg cagctacata tatccctacg atcgtcgtta ctgctaggaa
     5761 gatgcgcaat gggttgaagg gataacaagc ttttacaact gccatgcaac tgatcccaat
     5821 cagcaagtaa tacatcaaag tagtagtttc agcatttccc catgcgaatg tttttccaag
     5881 tagatacacc gcaatgatat tcactactac aagcaaggca tttggtaaag cattaataag
     5941 tgctgtaggc aaataacggt aagtgatttt tcttttatct tgttcaaaag ataaaaagaa
     6001 ggaaggatac ccttcaatcg ctaaatcaat cagcgtgatt tggataggga taaacggaaa
     6061 tccaattgct gtaacggcac atataatcga taaaataaat gaataaatcg ttttgataaa
     6121 aaagatgcct gagactttcg tcacattgtt gaccactcgg cgtccttcaa acaggacttc
     6181 tggcaatgta gtaaaatcag agtccaacaa taccagattc gcaatctgac gtgttgctcc
     6241 atcaccttct gccatagcaa tgctgcaatc tgcttctctt aacgccaaaa catcattcac
     6301 accgtcgcct gtcattgcaa ccgttctgcc gctttctttc aattcattta ccagcaattt
     6361 cttttgctgc ggactcactc gtccaaaaac cgtatagcga tgagcagctt ctcgcacttc
     6421 catttcttca gtaatttgag aaagatcgac atacgcatca taattcggta atcctgcacg
     6481 tctagcgata ttggagacag taaaaggatt gtctccagaa atcactttca gatccacacc
     6541 ttcctcatga agataagcta gtgtttcttg agcgtttttt cggattggat catcgatttc
     6601 aaacagagca accggctcaa caaatgctgg tttttcttcg ttcaattgct gatttggagc
     6661 gatccccaac ataagtacgc gatagccatt cgcttgggct gtttttagac tgtccggaag
     6721 ccgatcttct tccaccaaac gttcaggcgc tcctacgtac acgactccca gttctggaaa
     6781 ttccatcgcg ccccatttgc gatcagaaga aaatgcgact ttgtttgtca catcataccg
     6841 attagaaagc tcaaaataat ctctcatagc ccgcatagtg atgttgttat cactgctttc
     6901 tgccagatac gtccccataa tttctgggat ggctttctcg tacagcggat gtagtgcttc
     6961 tacccgctgg atactcattt tcccttcagt aatggtccct gttttatcca agcataatgt
     7021 atcgacatgg gccagcgttt caattgaata catgtcttga acaaggattc gtttttttgc
     7081 cagtttggtt acccctgtcg ttaatgcaat acttattagc aataccaaac cctttggaag
     7141 catgcctaac aaagctgctg cagatgcaat aacagaaatt ttgatagaag catcgcggat
     7201 gaacagtgct tccaaaaata gtatgatccc caaaggaata atcacgaaac tagtgaattt
     7261 ggatactttg cgaatcgaat ctacaagttc agaacgaata gctttgtgag tctttgcctc
     7321 gctagtcaag cggacagcat aattatctgc acctactcgg ataacttcag ccatgacaga
     7381 accgcttgtc aaaaagcttc cagaaagcaa ttcagctcca gtttctttga caatcaaatc
     7441 agattcgcct gtcaaaagag cttcatttgc ttctgcccgt ccagatataa cctgtaaatc
     7501 ggctggtatc tgttctcctg ctccgatttt taccaaatct cctaatacca gctctttagt
     7561 agaaatcgat tgttctttac cgtcccggat cactagtact tctgattggg aaacaatcga
     7621 taatttccgt acaagatttc ttgcatgtat ttcttgataa attccaataa cgatattgac
     7681 gacaataatt gctaaatacg ccatgttgga atacgcacct acaaataaca gacaaatccc
     7741 aataccaaag ttcagaaaat tgaataacgt caatatatta tcgctgaata tttgttttgt
     7801 actttttgat gcatcttcct ggtagtcatt ttgctggcca gaagccattt tctgaactac
     7861 ctcttgctgt gtaagtccat tcattttctt tttctccatt ttccgccaac tttcaaaaat
     7921 aatcacgtgt ttaagtctag cgtgttccaa gattaaaaac aacttgtttt tataaaattt
     7981 atagaaaaac acacgaatga ttttacaaaa aagatgccaa cctttttgtt tgaatcaccc
     8041 gtgtgctgtt tttattatca atctatcttt acttatattg ttcctccaaa cggctcatcc
     8101 accaacctag tgctgtaccg gctataaaaa gaacaggaca agctagtacc ccagcaactc
     8161 ccaatcccgc gtaatcggta ggaatgatca taatcgttga agcaaaaact acacctaaaa
     8221 tgaaatggaa tagcttgcta tatgcctttg agaaaatgta atccatgatt tttgacaatc
     8281 caagaacaca aagaatccca ccaattccga tcggcacaat cacttcaagt cgtacttctt
     8341 taaatccgtc agccatcgct ttatacaatc ccatatacac caaaaaatta gaagggctca
     8401 atcctgggac gatcataccc aaaccaatca atccgccggc aatcagccat gttccaaaat
     8461 tctgatcgac ttgcccgtca aataattgag cgccgtataa taaaaacaaa taagccagaa
     8521 caaaagtaac aaccatgatg atcacatcag aagtatctct tccttttttc cctgcttctt
     8581 tccataacgc aggaacagtt ccagcgatac atccgacaaa aaaccataat atcgttgttt
     8641 catacgcacc taataaaaaa ctgactaaaa aagaaagtag aaagatgcct gtcactccgc
     8701 ctagaccaac aggcagaaaa aacaaaacat tttctttgaa attttttgta aggtgggcta
     8761 aaaaagaaat cagccgctca tacatgccaa agacagctgc taatgcacca ccgctgactc
     8821 ctggcaagat aaatcctgaa ccgataaaca ttcccttcac aaaccgtaac atccagtctt
     8881 tggttgtgta ccccacttct tgattttcca ttttttgcct tttttccact atttgcgcac
     8941 tccttctttc atttaatttt attcatgatt gaacatttcc tgctatttta cttaaagact
     9001 ttttcatagg tctctattat tttttcattc attttgacaa tatcaggata aaacatgtta
     9061 cctccattat gatagagata gccgccattg taaagcaagg actggatccg ccaatatcgg
     9121 tattgtttcc cttcctcatt tcctaaaagt gggctcagca catctttaga atacgcttct
     9181 gctaattcta ctgtgttttc tccgccatga ttttttacat aggcaatata atctttccca
     9241 aaattatatg cttggacagc tgtccataaa tcgcatcctt gtttctttgc ttctactatc
     9301 atttccgcca aatatttgac accttgatca atactgtcag ctggattatc aatgatctca
     9361 gcttctccat gcagactttc cgagctctgc atgagatctg tcccttttcc ttttgattcg
     9421 gtcaatatta tcgccttgat caaattctcg tagttttcca tatgataatt ttttgcagct
     9481 gttgttattt ctatttgata gctttccact cgttttaccg aacgataagt tcttcctcat
     9541 aaaaacaaca ccgcaccaat aaccgtcaga atgatcatgt aaaaaagaat acggataata
     9601 gataatcgtt ttcgcttcat ttcatcacct agttattttg acatcttttt ttatcttact
     9661 atttctttat cttcttggct atttcttcct tgatttctgt gtacgcctta agaaaaaatg
     9721 aattttcctg tattttttga catcttacga aaatgatcgt tgtttttcag taaaaacaat
     9781 tgcccaatga ctgatataat cgttatactt tacacagtag gtgattatgt gaaaaaagaa
     9841 aagaaatatg caaaaatgcc agatgggagc gaaatttact atgaaaagag cggtcaaggc
     9901 ttccctctct ttttactgca tggcaatgac ggcagcggcc gctttttttc agaacaggtc
     9961 cctgtactcg aacgctacta taccgtgtat ctagtagata gccgaggaca tggtcgttcg
    10021 acaaacgaag catctatgtt gaattttcag ttaatggccg aggatctgaa tacgatcatg
    10081 ttgctggaaa aaatcgatca ggcagatttt cttggattta gtgatggagc aaatctagca
    10141 ctggtatttg ccagcagctt ccctaaaaaa gttcatcgat tgattttaaa ttctggaaac
    10201 acgcttgtta aaggcgttcg tttttctgcc agagtcatca gtaatattca ttatgcatgg
    10261 gtatggttac tctctttatt tcgcccaagt cttcgcaaaa atcttttagt tatcaaactt
    10321 ttgctgcatg acatcgggct tacagaaaat gatttaaaaa aaatcaactc ccccactttg
    10381 atcatcgtgg gaaaaaaaga tgtaatcaag ctaaaacatt ctttgtatat agctaaaact
    10441 ataccaaaag cttcctttgt gcttgtgaaa gaacaaggac atgaattagc tagaaaagat
    10501 cctgaacgct tcaatcgaga agttcttcaa tttctttctg aaacataact attaggaata
    10561 gaaggtgatt tatttgttaa aaaataccat acaatggctg aaaaaccacc taggactgtt
    10621 caaaacaatc tttttgattt ctgtcattgt cattattgtc ggtgaattga tgtccatcgg
    10681 taaaactcta tctatccagc aattaggaga aacgtttgcc actatacctg tatggaaaag
    10741 cggactaatg ctattgattg gtcttatctc tgtgttacct atggttggtt atgatattat
    10801 tttgaatcgg atgcttgaac aaaagcagaa tcctcgttac ctgtttgaga caagctggct
    10861 gatcaatacg atcaacaata ttgccggttt cggcgggttt gttagtgtgg ggcttcgctc
    10921 tgaactatat ggacaaaaga aagagagcag aaacgtgatc caagcattat cgaaagtttt
    10981 cttgtttttg atggctggac tttctattta cagtctgctt tcttttttac ttgtagtctt
    11041 cacgccagtt gctccttttt tgaagcaata ttggatatgg ttgatcggcg gcggtctata
    11101 ttttcctgtc gtctttttat ttactacttt caaaaagaaa ggattccttg gtggtacctc
    11161 acttaaaact caaggacagc tattgctagt ttcattgttg gaatggaccg gtgtcctgtt
    11221 tagtttcctt tctgttggtt atttaatgga aatccggatt gatctgtggc aaacaattcc
    11281 attattcatt gctgcttcag tgataggaat cgtgtctatg attccaggag aaattgggag
    11341 tttcgatgta atgatgatta tcgggttgtc cgctattggt gtgccaagag aaatagtcgt
    11401 tgtgtggatc ttgctctatc gcctgttcta ctacatcatt ccgtttttga ttggaatcgt
    11461 ctttttcttc aaaaatatcg gttccacttt tgatcagcgt tattctggta tccctaaaca
    11521 attagcaaca gaaattgcgc ataaaatcgt ggttgtctta ttatactttt ctggaatcat
    11581 gctagtactt tctgccacta tcccgcaagc ttttacagag tttcgctggc ttcatagttt
    11641 gaacccattg aaatttcatt ttattatcca atttcctagt atactattgg gatttctttt
    11701 aatcattatg ggcagaggga tcgcagcacg tgtgaaacga gcatatttgc ctacaatctt
    11761 cttgattgtt ctagctttac tttatgtttt attaagtgat tttagtttca caccggtggt
    11821 tttcttgtct attctgcttc tgatcattct tgcttctaaa aacgaattat ttcgggaaca
    11881 attgatctat tcatgggagt ggcgtacgat cgatggaatc attattggtg cactgtcctt
    11941 gctttacatc gttattgggg tatacaatct gccggatttc cctcatcggc gtcaccattt
    12001 tatttccttt ttcttatttc cttctgaaaa gatttggttt tcgggattgt tggccatcat
    12061 cgctgttagt ttcatgatcg ttctatttgt tcatttcctt caaggagaaa agaaacagat
    12121 tggcgaagcc tttaatgaag aaaaggccct gaagatcctt acaacttatg gaggaaactc
    12181 cgatagtcaa ttgatcttct taaaagataa gcggatgttt gcctatgaaa aagacggtga
    12241 accaactgtt cttctccaat tcgcttgctt caataataaa tgtattgtaa tgggtgatcc
    12301 ttctggtaag aaagaagatt ttccagaagc aatcgaagct tttatcgaag aaacagatcg
    12361 actatgctat ttaccagttt tctacgaaac aagcgaagag attgttatga ttttgcatga
    12421 attcggctac gatttcatta agatggggga agaagcttat gtagacctga atagttttac
    12481 aacttcaggg aaaaaaatga agggcactcg tgctgtcttg aatcggatcg aacgagaagg
    12541 atttacattt gatgtcttac aaccaccatt ttctactgag caaatgagtg ctttcaaaaa
    12601 tatctctgat aattggttgg gttcacgaaa ggaaaaaggg ttttctttag gctttttctc
    12661 tgaagattat ctacaaagag cgcctattgc agttgtcaaa aatacccaag aagaaattgt
    12721 cgcttttgca acgatcatgc ctacttacac gaacaataaa gtaggaacga ttgatctgat
    12781 gcgatatgat tctaaaaaag caccttctgg cagtatggat ttcttgttct tgcatttgtt
    12841 tgcctatatg aaagaagaac atatccaatg gttcaattta gggatggccc ctctttcaaa
    12901 tgtcggaact tccagaaaga gttttttaca ggaaaggatt gcatacttgg tttacgagtt
    12961 tggttctcat ttttattctt tccatggatt aagagaatat aaaagcaagt acgctacaaa
    13021 ctgggtctca cgttatactc tatattctag agatagttgg attgcatatg ttatgattgc
    13081 tttgctgatt attgataatg cgccagttga gcagacacaa ggtagaataa gtggtttgaa
    13141 aaaatggata cgaagaaagt attaaaaact gcataccgat agatgaacac tctcatgatg
    13201 aataaaagag actgaagtaa aacgaaagtt catgcttcta c
//
LOCUS       DAFEIE010000070        13137 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFEIE010000070
VERSION     DAFEIE010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.073"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(47..1513)
                     /locus_tag="LP345_002285"
     CDS             complement(47..1513)
                     /locus_tag="LP345_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBL1761050.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1900..2496
                     /locus_tag="LP345_002286"
     CDS             1900..2496
                     /locus_tag="LP345_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL1761051.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2554..3036)
                     /locus_tag="LP345_002287"
     CDS             complement(2554..3036)
                     /locus_tag="LP345_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761052.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3142..3339)
                     /locus_tag="LP345_002288"
     CDS             complement(3142..3339)
                     /locus_tag="LP345_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761053.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3634..4392
                     /locus_tag="LP345_002289"
     CDS             3634..4392
                     /locus_tag="LP345_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL1761054.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4452..4880
                     /locus_tag="LP345_002290"
     CDS             4452..4880
                     /locus_tag="LP345_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761055.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4926..4998
                     /locus_tag="LP345_002291"
     tRNA            4926..4998
                     /locus_tag="LP345_002291"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4959..4961,aa:Gln,seq:ctg)
     gene            complement(5148..5519)
                     /locus_tag="LP345_002292"
     CDS             complement(5148..5519)
                     /locus_tag="LP345_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1761056.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5734..5919
                     /locus_tag="LP345_002293"
     CDS             5734..5919
                     /locus_tag="LP345_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761057.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6002..6190)
                     /locus_tag="LP345_002294"
     CDS             complement(6002..6190)
                     /locus_tag="LP345_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761058.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6214..6477)
                     /locus_tag="LP345_002295"
     CDS             complement(6214..6477)
                     /locus_tag="LP345_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761059.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6635..6892
                     /locus_tag="LP345_002296"
     CDS             6635..6892
                     /locus_tag="LP345_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBL1761060.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6963..7154)
                     /locus_tag="LP345_002297"
     CDS             complement(6963..7154)
                     /locus_tag="LP345_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761061.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7295..7615)
                     /locus_tag="LP345_002298"
     CDS             complement(7295..7615)
                     /locus_tag="LP345_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761062.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7638..8072)
                     /locus_tag="LP345_002299"
     CDS             complement(7638..8072)
                     /locus_tag="LP345_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1761063.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8407..9045
                     /locus_tag="LP345_002300"
     CDS             8407..9045
                     /locus_tag="LP345_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1761064.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(9369..9452)
                     /locus_tag="LP345_002301"
     tRNA            complement(9369..9452)
                     /locus_tag="LP345_002301"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9416..9418),aa:Leu,seq:cag)
     gene            9980..10480
                     /locus_tag="LP345_002302"
     CDS             9980..10480
                     /locus_tag="LP345_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1761065.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(10670..11014)
                     /locus_tag="LP345_002303"
     CDS             complement(10670..11014)
                     /locus_tag="LP345_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBL1761066.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(11168..12088)
                     /locus_tag="LP345_002304"
     CDS             complement(11168..12088)
                     /locus_tag="LP345_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1761067.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            12275..12766
                     /locus_tag="LP345_002305"
     CDS             12275..12766
                     /locus_tag="LP345_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBL1761068.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(12790..>13137)
                     /locus_tag="LP345_002306"
     CDS             complement(12790..>13137)
                     /locus_tag="LP345_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBL1761069.1"
                     /translation="RLIGSMIVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMN
                     KVLQAGGRVIRGMADQGIVVLADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRF
                     WLSKEAVNQKNEE"
BASE COUNT         4177 a         2585 c         2121 g         4254 t
ORIGIN      
        1 acaggaactg ctgcaaataa gcaattcctg tttttatgtt cattgattaa tgaatagagc
       61 ccattagttt tttgattggt tctttcacag taaatagcaa gataccaccg acgattgcta
      121 ctgcaccgat aataccgaag taagcagatt ctgttcccgg tgtgtagaag cgtgcaattt
      181 gtgcattgat tgcttgtgaa gaagcatcag ctaagaacca aatagcgatt gtttgtgatt
      241 caaatgctcg tggtgctaat tttgttgtca cagacaaacc aactggtgaa agacacaatt
      301 cagcaataac cacgatgaag aaacttccca acaaccacaa tggacttact tttccacttg
      361 taccataaag catacccggc aacatcaata gcaagtacga taatcctgca aataaaagtc
      421 caagagagaa tttcactact gtagatggtt gacgttcacc aagtttcgtc cacatcgtta
      481 cgaatactgg tgtcagaata aagatgaaaa ttggattcaa tgattgatac cagcttgctt
      541 ggatcgttac accaaatagc gtagattgtg tacgttcact agcaaataaa gctaagatag
      601 atgaaccttg ttcttgtaat gaccagaaaa tgattgctgc aaggaataat gggatataag
      661 cccatactct tggtttttct tcagcagtta catcttttga agtcagcatt ttgataaagt
      721 aatacaacgg taagataatc cccaatacac tgattgtatt gacaaaaaag tcaattgtca
      781 gatgaccagt tagttgtgcc ccgccgaata ctgcagcgat aacaacaagt gcgatgatca
      841 agttacggat gaatccttta cgttcttcag ttgtcaaagg attcggcggt gttgtaccca
      901 ctccgtctaa tgtcttgcgt ccttggatga tgtattgtaa taatccaaag aacatcccaa
      961 tagcagctaa agagaaccct aaatgatagt tatattcttg accgattgta ccaacgatta
     1021 gtggtgctaa taatgcccct aagttgacac ccatgtaaaa aatcgaaaat cctgcatctc
     1081 ttcgcaagtc agtctttgaa taaagatgtc cgaccatgcc agaaacattt ggtttcaaaa
     1141 aggcggttcc gataataatc aatgccatcg aaacaaacaa tgtacttaca ccaaatggta
     1201 aagccaagac gatgtggcca agcataatga aaactccacc gaagaataca gtgcgttttg
     1261 ctcctaacac tcggtcagat acccatccgc cgacgatact agacatgtag atcaaagatc
     1321 cgtagatcga catgatagct aatgctgttg ctcgtggtaa tccaagtccc ccgttggcaa
     1381 ctgtatcgta catataatag ataagtaatg cacgcatacc gtaataacta aatcgttccc
     1441 acatctcagt gaagaacaaa gttgacaatc ccttcggctg cccgaagaag cccttgtctt
     1501 gctgtttttc cataatctat accccaattc tttaaatttt cagaaaatat tatacatctt
     1561 taccgaaaaa tttaactaaa aaacttattt aagaaatata aactaatttt ctataaaagc
     1621 aagtaatttt taatggcaat atcataaaaa aaagaagata gagatttaat aattatatat
     1681 cagctgtttt tttcaaataa gcaaaaattc ctaaaacaca acaatgaaag cgataactaa
     1741 gaaaatcctt acataacgat ttttcttatt aaaattgttt tttgaacttc gcttattttt
     1801 tgtgagcata tctgtttact tactttttgt aaggtgctat acttcatttc gtaatcaatt
     1861 aaaaaaatgc aaaacgcaaa tcaaaggaga aattttatta tgacaacttt tactgacact
     1921 ttgaaaaacc gccgttcaat ctatcatcta ggacgtaatg tttcactttc taatgaagaa
     1981 ttaacaactt tgatcaaaga agcaattaaa gaaagcccaa ctgctttcaa tgctcaatca
     2041 acacgcgcag ttatcctttt cggagatgca catgaaaaac tttgggaaat cactgaagaa
     2101 gcacttcgcc cattgactcc agcagaagct ttcccaaata cacaaaacaa attagctggt
     2161 ttcaaaaatg gttatggtac agtattattc ttcaaagata ctgacgtggt aaaaggtcta
     2221 caagaacaat ttgaattata tgcagacaac ttcccagatt ggtcagaaca atcaaacgga
     2281 atcgcaacag ctaatacttg ggtagcatta gttgataaag gattgggcgc aaacttgcaa
     2341 cattacaacc cagttattga cgaagcagtt gcaaaagaat ggaatatccc ttcaaactgg
     2401 aaactacgtt cgcaattagt attcggttca ccagaaacac cggctgggga aaaagaatac
     2461 atgaacgatg ccgatcgctt ccgcgtattt ggataatttt atttgaaata aaaaacagag
     2521 gttgtgacaa acatcttgtc gcaacctctg tttttattct ggatcaatca taatatcaat
     2581 ctctgcctca tcgtttaagc gttgggacaa aaatggaact aattcttcta atgatgcaga
     2641 aaatttcagc atcggtcctc gccatccgtt tcggaaaaaa ttcattttta cgattttaga
     2701 accttttggc tgatataata caattttatt gatctcagaa aaaggaacac cttttttgtc
     2761 aaagctattc aaaacaagtc cttcttctgt gattcctcta ctgtccaaca aaaaactaat
     2821 aaaaatcatt gctgacaaga tcccttttgc caattcatct gctgtaggat gactgatgag
     2881 tgtataccaa atgactagtg acactaagaa gggtatcacc aagtagaccc atcgatttcg
     2941 cacagtccga taaataattt cttttcgaac cagccaaaga aataaaaaca tcacaacaac
     3001 gaataaaaac aatagaaccg taaagaatgt taccatgaca actcgcctcg ctttttcttc
     3061 tccagaaaat aggaaaagaa tactgattta ccttctcaaa gaaattggac ttgcagcacg
     3121 ccgcacgtcc aattgttttc tttattcaaa tgtatcatat tttgcaacaa ccatgcttgc
     3181 tttttcatct aataattctt ggtcctctgc agcacattgg gcaactttga ccacggcgca
     3241 gtttgtcatt tttgatacaa cttcaccaat gaccgttttt gtaaaaccaa ttggtttgca
     3301 tgcatattgt tctcctaaat taatcatttc ttccgtcatc aaaatcctcc taaactgctg
     3361 gaacttttct ccacattacc actgctattt ctttggagat ttaactcatt gatttttatt
     3421 tacagttaaa aatcaacctt acaggcatta tagcgtactg ttttcgtttt cacaattaaa
     3481 acagctgttg tatttagaag aatttttttc aaaaaattaa aacatattcc ttaaaaacta
     3541 attatttcct acatattaaa atataatact tccatttcca ataaaaatac atttataata
     3601 ggaaagataa acagctgaaa agggagattt caaatgaaga aaaaaacgtt caaaaaacta
     3661 ttgtttctag ggggcacagc tgctctttta ttaagcggta caagttatta cctacatatc
     3721 cattctccag aacatacaat gaacactgca caaaaaagtt caacacaaaa aacgaaaaag
     3781 acaaaagaga aagcagaagt tttactagat gttccattag agagccagtt tgattctcct
     3841 tctttagaaa atggctgtga agtcacttcg ctttctatgc ttttatcttt ttatggttat
     3901 gaaacaacta aaaaccagtt agctgagcaa ttggattacg tccctgtttt caatgcagat
     3961 gggactcatg gcgatcctaa tgaaggattt gttggtgata tcagtggcgg agactgggct
     4021 atggtcgtct atgttccccc agttgcctcc cttgctcagc aaatcgtcca aacggattat
     4081 cacacttttc caaaaaccga tgctcaactc gatgatatca aaaaagcact atctaaagga
     4141 aatcctgtct ggacttctgt gactatcaat tttgaagtcc cagatgaaac tgattttatg
     4201 acttggacca caaataatgg agaagtaaga gtcactcctc ttgttcatgc ttgtgtagtc
     4261 actggatatg acaaagaaaa tatttatgtc aacgatccct atggtgtaaa aaatcgagca
     4321 gtaccgatca acgatttttc ggcgattttc actgcaatgg gtggacagat gctaactttg
     4381 gagaaaagct agtaattcaa acaaaaatcc cttatactca agataccaaa cctttgaagg
     4441 gagcgtagat aatggaaaaa ttcacacata aaaaaatgga tccaaatgaa attccgatta
     4501 tttttgtccg tgactgcaag ggaaatgttc aaggtaaagt ctctattaat gagtggaacg
     4561 agcgtcgcag acctgctacc ctcaatgaac tggaaatcaa attgtatcgt caatctcttg
     4621 tttattacgc agatcaagag tacgagaaag ccaccgattt attgaaattt ctaattgctc
     4681 gaacagagta tactcgcttt gaatatattg aacgtttagc aaacatctat catattatga
     4741 atgaacctgt caaagaatat cagttattgg acaccgtctt gtcagtagca gaactgattg
     4801 cccttcctgc tggattagaa aagaaactag tacgccgcct tttacgagta aagcaacaac
     4861 tatccgatca agaaaaataa cttgcgtttt tttaggaaag tgctatgatt attttgttga
     4921 ataaatggga tgtagccaaa ctggtaaggc acttgactct gaatcaagca attgtaggtt
     4981 cgaaccctgc catcccaatt tgatgtgctt gctgaaaaaa tgaaccccct gtaaaagaac
     5041 aatctttttg cagggggatt attgtattat ttttactact tgtatttagt ttacataatt
     5101 aaattatgaa taataaaatc gggcgtattc ttaatacaaa aactgattta cccaataatt
     5161 gctaatgctt tctccggaac tttttctcta ggaacttcct catacgtttc tatgtgtgct
     5221 cctttattgc taattttcaa ataatgattt tcttttaaca cagaaagacc attaaattca
     5281 accgttcgtt ctttcccatt ggcatcagca gctttctgca cataccttgc tgtaccatat
     5341 tcatttactt cctctggttt ttgtgtcttt acatagacct ctcctttttc aactaatgga
     5401 tttagctgat caagtatacc agggatttct ccataacttc cttcagtata atatttcagt
     5461 ccaaatagca aaataccact aatcgccgcc agtccaatca aatatttaat cactttcatc
     5521 tttctacctc cttgttatat attcagtata tgggtcagtt aaagaaattc catccgtccc
     5581 aagttggaga tttttctcct actttagaag cgagaatcga gtgttttttt agtaaaaatg
     5641 atcgttattt gatattattg acgtgtggat aaatcagttt ttctcgtttt gtccatgtaa
     5701 aaaatcatgt tgatagcaaa ggatgtgttc aaaatgaatc aagaagaatt atttcaaaaa
     5761 gtcaaggaaa tgattaagaa cggcaatttc gatggcgcaa aacgatttat cgaagaacat
     5821 aaagaacaat taggacctta taaagagaaa gcccaaaatc ttttaaaaga tgtaaatatc
     5881 gacagtgtca aaaacaaatt taaaaatcta ttcaaataag taaaactttc acttttgtaa
     5941 aatcaaagga ggacaatgct gctgcatcgt cctcctttgg ttcttttctg aatacttcat
     6001 actaaaataa acgtgtcgga tcgtaatgat aagtcacatt gccgttcagt gaggcttttc
     6061 ccaccacata tttacgattc tccaacttca gccacgcttc tcgaaaagcc attaattctt
     6121 ctctttttac atcaatcttt tcgatttttc catcgatcaa atcttgaata agttgttcat
     6181 atggattcat ttttttcctc catctgctgt caatcaataa gttgtaaaaa taggttcata
     6241 tgcttttttg gtatctagat cttctctgac tttgactgtc gtataaataa ttttttctac
     6301 tgggatacta taataacttc cttcaccatt attgaatcgg tgaacgtctt tctttgctaa
     6361 aataccattt attttattcg tcagtacacg ttgttcgaca ctgttactta caacatagta
     6421 aatcacccga atattattga tcaaatgcaa atcgatttct aacactacat gatccatgaa
     6481 aatcccactc cttctttcac tttgattata gcaagtttct cctctaattt caaaatcgat
     6541 acagatttta ccggataaat ccacaaaact gcttgcgcca tttcgcacaa agtgttattt
     6601 tgtatcatgg actttattta tcggaggcaa tagtatgatc gcgatcggtc aatttgtttt
     6661 ttatattcct ttttttatta tgataagcat tcttttctat tacataaaat ggacaaaaaa
     6721 gaagttttca gttttactgg cctctttacc tgctgtatat tttacttatc aaattttttc
     6781 ttttaggcat tgggaaacaa cgtctgtatt aataacacac atcatcgaat tgacgctttc
     6841 agtaattttt cttattattt ggatctattt tttatataag aatcagaatt gaatccctcg
     6901 catgtttaaa aagaaaacga ttaaagatgc agcaaatttc tgccgatctt taatcgtttt
     6961 ttctattctg ttataccaaa aaaatgtttg aatcggtgaa ggatcgttcc ttgttttaat
     7021 tctataaatt cttgtgcgat cgggtacttt tcttccaaat tttctttgtt cttttcgatc
     7081 aggcttttcg cttcttcata ttttttatct gcacatagtg cttttacttc ctgtaatact
     7141 tttcctgctt ccatttgcct caccctcttg ccattttatt gctttaagtt ttatttaagt
     7201 tatacgcatt attctagttt catcccaaat aacctttttt catttttact cctcgaacta
     7261 atcagttttc taaaggctga ttggttcgtc ttttttattt ttcctccatt tcattctgct
     7321 cttctgttaa tttatctaat gctttgattg atgctgcggc tcttgcataa tcatagctgt
     7381 ataattccat aaatttatca ggcagaacaa accacgctgg atgataaccg ttagctgtga
     7441 cagggaatcc tttatcttgt tggttatctc catcccatct cagagcaaca cctttttttc
     7501 ctttccactt tactaaagcg atcgagtatc ccttctttgt ttgtgtgccg tcttcaataa
     7561 ttgctaaaat ttctattttt tcttttggcg cacggacttc ttgaggacga accattttct
     7621 attcctccct tatctcatta cttcacgacc aacacactgc aaggggcatg tgatacgaca
     7681 taagaagcgg tcgatccaac taatgcttgt tgtatagcac cttttcctgt cgctcccata
     7741 acgatcaaat caatattttc ttgtccaggg atgacattgg caatcaaatt tcttggatct
     7801 ccagtttcaa ctattgcgtg gatctcagca atgccgtact ctttggcatc attgattttt
     7861 ttcagcatgg ctacttctgt tctttgtttt tcatctgcat agatttttga aaaggcatag
     7921 gcactatggg tcagctcaac tttgttgatg attgacacga taaataagtg ggcttcattg
     7981 tcctttgcta agtcaagggc ttcagcgaac gctttgatcg attgtcttga tccgtcaact
     8041 gctaccatga tgttctggta tcttttactc attggaaccg cctccttttt cttttattgt
     8101 aacatctcaa gcaaaaatac aaaaaatata cgcaatatgt aaataaaatg atgaacaaaa
     8161 gcaatttctt tcaagttatt tatacatttc ttttctcatc agaacacctg ttctaatccc
     8221 attatttctg cattatgtga aattcctcat catttttcac atcgagcgaa catcattctg
     8281 ttacaaaaaa cgtggatttg tcataaattg tcatgcttct tttacctatg aaatattttc
     8341 acgtgttaaa gtattcctcg ttgaacacaa caaataaaac tttttaacga ataaaggaga
     8401 tttttcatga catcacttaa aactttactt tttggaacaa ctttggctgc cggcgctgca
     8461 ttcttcatgg gaacgactgc tcatgcggac gaagcttata ccgttcaatc aggtgatact
     8521 ctatcaacga tttctcaaaa atacgttggt gataactcct tgatcaatgc cattgcagaa
     8581 tcaaattcaa tttctgatat taacctgatc tactcaggac aacaattaac aatcccaaca
     8641 gaaggctctg cacaagcagc tgctgaacct caagcagccg ttcaagaagc accagtccaa
     8701 gctgaacctg ttcaagctga acaacctgtt gtacaagaaa cggttcaaac ggaaacacaa
     8761 gcagcgcctg ttgctgaaac acaacctgct cctgctgtaa cagaaactgc tgctactcca
     8821 gcaagtacaa gctctgcaaa agaatggatc gcacaaaaag aatcaagcgg ttcttacaca
     8881 gcaacgaacg gacgttacat cggccgttac caattagatt cttcttactt aaatggtgac
     8941 tactctgctg caaaccaaga aagagtagca gaacaatatg ttacttcacg ttatggttct
     9001 tgggaagcgg cgaaagcatt ctgggaagca aacggttggt actaagattc attatttgaa
     9061 cgtttaaaca cattcaaaat atagtaagag gtcatgcgat ttattctttc gcatgacctc
     9121 tttttgagtt taagtttagt ctttattcct taactatcgt ttgccagtat ttcttgtatc
     9181 agaatctata aatctactat ttgaatcaat ctattaggtt ttaaactgtc ccaccttcac
     9241 acaaattttt tttgatttat ttgaatctgg ttccgttgtt taaaattttt cctatattct
     9301 tttagataat atgttatttt ctttctcatc gctccaggtg taccttctct ttataaaaaa
     9361 acaaattatg cggctaagaa gactcgaact tccacgaggt caccctcact agcgcctgaa
     9421 gctagcgcgt ctgccaattc cgccatagcc gcatcacatc ttttagttta ggattacatg
     9481 tgttttttgt caagaacata tttttgttct ttttcatttc tgtacgccct cccttatgcc
     9541 atctacacaa ataattcatc cgagcaactc catcatctat tgagggttgg tgaaaaaatc
     9601 tgttttatcc atatgatcga tttcaatgtt aaacgaacga ctctgggatt agtaactatt
     9661 ttattttttt cttcatttct tttttcctct ttttctcgat tcagctatct tctttcattt
     9721 ggatattgat tatttcttct gttgattact atccttctgg aattctagac gctgaagtaa
     9781 ttcacgtttt ctttcttcta gagatcataa gtaacgaatg aacgaacttc aaataatttt
     9841 tttattgtaa ttcatatttg tattgttcga tgattcttaa tacgatatga cacaataaat
     9901 aaaaataggc atggctattt acaacaatag tgctatagta gaaaacaaat gaataaggtt
     9961 acttaaagag gtgaatacga tgaaactgat caaactatgg gaagcagatt taaagaaagc
    10021 ttatcagcta caaactagct ttggaccaaa tgagagtgga tttatcaaca atgcttatgg
    10081 ctatacattt gctgaatttt tagattatgt aaaaaaatgc gaaaaaacgt ctttaggaat
    10141 cgatcttcct gagagttacg ttcccgcaac cgtctttatt ttagaaagtg atgaacatga
    10201 gtatgtagga atttttaatt tgcgccataa actgaacgaa acattaagaa acggcgctgg
    10261 ccatattggt tacggcatct cccctaatta tcgtaaaaaa ggatatgcca cacaaggatt
    10321 agcattagta ctacaagagg caaaaaaaat cggcattgat gaggcacttt tgtctgtaaa
    10381 taaaaaaaat cttggcagtc ttaaagcaca acaaaaaaat ggggctgcga tttatcgtga
    10441 agatgagaaa gaatactata cgaaaatcaa actgatgtaa aaaagaagga ttccaaaagg
    10501 aaagggattt gaatgtcctt tatcaataga acacatttat ttaattaact tataatatag
    10561 cagacaaaat tttataaaca aagaaacctt ttatctcttt tcttctagaa aggataaaag
    10621 gcttttttgt ttttcctatt tgcttctcat agctagtcag ccaagatttc tatcgtatcc
    10681 ccaacgcaat ccgtgcataa cggctcatct tatctgtcgt ccatgctgga taccagacta
    10741 gtttgacttc tgctttcgtt acttctggca cttcttttaa tgcgtcatgg atagattctg
    10801 ttaaaatatc tgctaatgga cagcccatag ttgttagagt catcttaatg actgtttctc
    10861 cattttcagg attgaattct atatcataaa tcaagcctaa attgacgatg tcgattccta
    10921 attcaggatc aatcaccatt tccaaggcag caagaatacg ttctttgatt agttctattt
    10981 cttgtccaga ccgttcttgg tttgcttcgc tcatcgtacg acactcctta acacgatttt
    11041 tatttatcat actctttttt tagctgcttg taaatgagaa tttagaagta agattctcgt
    11101 ttaaatttat aaaaatgttc ttattagatg taatagatta aatttattct aaaataaacc
    11161 tgattcctca ttttttttgt gaacgatttt ttatttctgg caatacgcca gttgttcgat
    11221 acattttttg ttcgttttca tttgcaaacc ggccaaatac tgaatgagtt ggtaaaatat
    11281 tgataaatgc atcgtcgtcg atttcatgaa cgatctgatc aagatcatac atttcgtagc
    11341 gggtgatgac catcatgatc atgttccctt gtttttttga atagccaccg acagacggca
    11401 gtaatgtcat tccacgtacc atccgttttg ctagttcttc tgttacctct tctggcttga
    11461 cggtaacgat cattgctgtt actttttgat gactcgtgtg gatggcatca attacttgag
    11521 tcattgcata aatggaaata atcgtataca aggcactttc ccagttaaag aagaagcctg
    11581 cgatgactac aatgatacca tttagaatca gcatgtagtt tccgactgtt tttccagttg
    11641 tttgtgaaag tacaagagag atgatatcca tcccaccagt tgtaaagccc atttttaaag
    11701 ataatcctac gccaagacct aataaaacac cgcctactag ggcattcatc aaaatattat
    11761 cagtgatctg tccgactgga agcagcatcg tcatcaccga tacacataca acattcacaa
    11821 aactaaggat cgttgctcgt tttcctactt tgagaaaccc taatacaaac acagggatat
    11881 tcaaaagaaa aataaatgtt cctgtgtcta tcttgatatg aaaccattca tataaaagcg
    11941 aggaaatgat ttgagcgatc ccattcatcc ctgcagaaaa gacattggct ggaatcaaaa
    12001 aataatttaa agcgaccgca gcggtcaatc cggttatcaa aataaccact attttcttta
    12061 atctttcatt tttatgatac gcagtcataa ttttactcac aagcacctct cccctacttt
    12121 ggtattccaa atgtaagaat aacagtttat ctattaaaat aaaatacttc gaactcaaat
    12181 gagaagaatt ttagcaaaca ggtaagaatc tgccctaatc ctatgataag atagatgtat
    12241 ggtaaatatt tatatgtata tcaggagggt tcctatggca aaagatgcta gcttcgacat
    12301 tgtatcagaa gtcaatacag aagaagtaaa aaatgcgatt cagcaaacaa caaaagaatt
    12361 gtccaatcgc tttgacttca aggattctac agtagaaatc aaattagaga acagcaatct
    12421 agttgtattg agcgatgatg atttcaaaat cgaacagatc aaagatgtat tatttggtaa
    12481 gctgatcaaa agaaatgtgc caatcaaaaa tatccatttt tccgaatcag aacacgctct
    12541 aggtggcaaa gctcgacaaa ctgccgattt ggtcaacgga atcgatcgtg aaaacgcgaa
    12601 gaaaatcact acagctatca aaaatgaaaa actgaaagta aaagcacaaa tccaagaaga
    12661 tcagattaga gtgacaggta agaaccgtga tgatctacaa gctgtgattg ctttattacg
    12721 taaacttgac ttaccaatcg agttgcaatt cactaactat cgttaatcaa aaaacgaggc
    12781 tgacgtctgt cattcctcgt ttttttgatt tactgcttct tttgataacc aaaaacgctg
    12841 tattccttct tccaattccc caacacttcg tacttctctt gctgtttgcc aatgttgtgg
    12901 gaataaacgt cgataagaaa aactagaaaa tcgttgatct gccaatacaa cgattccttg
    12961 atccgccatg ccacgaatca ctcgaccacc agcttgcaag actttgttca ttccaggaag
    13021 ctgataagcg taagcaaatc caaggtgttc cttctcatca taatatgatt tgatcagttc
    13081 ctgctcatga ttcatctgcg gcaaacctac acctacgatc atactgccga tcaatcg
//
LOCUS       DAFEIE010000071        13049 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFEIE010000071
VERSION     DAFEIE010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.074"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(77..149)
                     /locus_tag="LP345_002307"
     tRNA            complement(77..149)
                     /locus_tag="LP345_002307"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="LP345_002308"
     CDS             530..1099
                     /locus_tag="LP345_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBL1761070.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="LP345_002309"
     CDS             1086..1946
                     /locus_tag="LP345_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1761071.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="LP345_002310"
     CDS             2136..2840
                     /locus_tag="LP345_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1761072.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="LP345_002311"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="LP345_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBL1761073.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="LP345_002312"
     CDS             4677..5993
                     /locus_tag="LP345_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761074.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="LP345_002313"
     CDS             5994..6863
                     /locus_tag="LP345_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBL1761075.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="LP345_002314"
     CDS             6918..7727
                     /locus_tag="LP345_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL1761076.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="LP345_002315"
     CDS             complement(7830..8459)
                     /locus_tag="LP345_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBL1761077.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="LP345_002316"
     CDS             8629..9921
                     /locus_tag="LP345_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1761078.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="LP345_002317"
     CDS             complement(9997..10659)
                     /locus_tag="LP345_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1761079.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="LP345_002318"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="LP345_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBL1761080.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="LP345_002319"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="LP345_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBL1761081.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGVETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4337 a         2254 c         2825 g         3633 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaaggggt
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttctt
//
LOCUS       DAFEIE010000072        13049 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFEIE010000072
VERSION     DAFEIE010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.075"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(148..1728)
                     /locus_tag="LP345_002320"
     CDS             complement(148..1728)
                     /locus_tag="LP345_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBL1761082.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2129..3505)
                     /locus_tag="LP345_002321"
     CDS             complement(2129..3505)
                     /locus_tag="LP345_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL1761083.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3633..4751)
                     /locus_tag="LP345_002322"
     CDS             complement(3633..4751)
                     /locus_tag="LP345_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1761084.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4893..5327
                     /locus_tag="LP345_002323"
     CDS             4893..5327
                     /locus_tag="LP345_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1761085.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5405..5938)
                     /locus_tag="LP345_002324"
     CDS             complement(5405..5938)
                     /locus_tag="LP345_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBL1761086.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6032..7210)
                     /gene="mutY"
                     /locus_tag="LP345_002325"
     CDS             complement(6032..7210)
                     /gene="mutY"
                     /locus_tag="LP345_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBL1761087.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7203..8000)
                     /gene="recX"
                     /locus_tag="LP345_002326"
     CDS             complement(7203..8000)
                     /gene="recX"
                     /locus_tag="LP345_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBL1761088.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8107..9489
                     /gene="rlmD"
                     /locus_tag="LP345_002327"
     CDS             8107..9489
                     /gene="rlmD"
                     /locus_tag="LP345_002327"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL1761089.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9663..10241)
                     /locus_tag="LP345_002328"
     CDS             complement(9663..10241)
                     /locus_tag="LP345_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBL1761090.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10563..11033
                     /locus_tag="LP345_002329"
     CDS             10563..11033
                     /locus_tag="LP345_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBL1761091.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11141..12367)
                     /locus_tag="LP345_002330"
     CDS             complement(11141..12367)
                     /locus_tag="LP345_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1761092.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3862 a         2628 c         2195 g         4364 t
ORIGIN      
        1 tttttttgat tagacatttc tatgatttta atatagtaaa aagagccgtc acggaaaatc
       61 cgtcacggct ctaaacaaaa tatgagaggc tgtttttgtt tggctattct tattacttga
      121 tgcagggcag cttgtgtcaa gacttcttta catcaaactt tttaatttta cattgggata
      181 tttatccgca aaccagcgtt ctgcaaattg gttctcgaat aagaacaacg gttggtcgaa
      241 acggtcacga gccaagatat tgcgacttga actcatcttc tcatccaaat cttctggatc
      301 gatccagcga gcgattttgt gtcccattgg agacatgatt acttcggcgt tatactcatt
      361 taacatacga tattggaata cttcgaattg tagctgacca acagctccaa tgatatattc
      421 ttccgttaga tatgttttat aaagctgaat cgctccttct tgaactaatt gatagattcc
      481 tttgtggaag gatttttgtt tcatgacatt ttttgcagtc actttcataa acagctctgg
      541 agtaaatgaa gggagttctt cataagcaac ttttagtttt ccttcgaaca atgtatcccc
      601 aatctgataa ttgcctgtat catatacacc gatgatatcg cctgctactg ctttttcgac
      661 gttttctctc gaatctgcca taaattgtgt gacattgctt aatttcagtt ttttatttgt
      721 acgttccaac cagacatcca ttcctcgttc gaatgttcca gaacagattc ggacaaaagc
      781 gattcggtca cgatgggctg gattcatatt tgcttggatc ttgaatacga aacctgaaaa
      841 ttcttcctca taaggactta ccatctgatc atcttgtgtt ttgtgtccat aaggagctgg
      901 tgccaattca acgaaagtct ctaaaaaagt ctgtacaccg aagttagtca atgcagaacc
      961 aaaaaatact ggtgtctgat cgccacgagc aattttttct tgattaaatg catctccagc
     1021 ctctttgatt agttctactt cttctaagac ttgttcatat aaggaatttt cagttagagg
     1081 atgattttcg ggaagcagtc catcttcatc caattctact aatcgttcat cctgataatt
     1141 ttccggacga taaaactcta cacgattatg gtagatatca taaagacctt ctagcccttt
     1201 acccataccg attggccaat tcatcggata agattcgata tctaatagct cttctaattc
     1261 ttctaacaat tccaatggtt cacgaccatc acgatctagt ttgttgataa aagtaaatat
     1321 cgggatgcca cgttttttta caacttggaa taatttcttt gtctgtgctt cgatcccttt
     1381 tgcactatcg attaccatga ccgcactatc cacggccatc aaagtacgat aagtatcttc
     1441 agaaaaatct tcatgtcctg gtgtatccaa gatatttact cgtttccctt gataatcaaa
     1501 ctgcataaca gaactagtaa cagaaatccc acgttgtttc tcgatttcca tccagtctga
     1561 tttggcaaaa ttacctgttt ttttgccttt tacggtcccg gcttgacgga tagccccacc
     1621 aaacaatagt aattgttctg taatcgttgt tttcccagca tccggatggg aaatgatcgc
     1681 aaaagttctg cgattgtcca cttgttgctt taattttgga ttattcataa cctaactcca
     1741 tttcttccat tcaattattt atattttctc taggcacaga ttgtccgatc tcttaaagaa
     1801 agacaatttc atatagggct gtgacaaaag ccgtgtagca gtctcttttt ccgagtaaac
     1861 ggcgttctag agacagccta tcagcaataa gcccacccaa gccaaaaata cgaaaagctg
     1921 tttttgcttg gctgctctta ttacttaatg caggatagct ttttcacaac ctttgtcaac
     1981 tactacaact gaatcagtat agcatggatt cagcgaatga aaaagccacc aaaccataag
     2041 agtcaaatat ttttttgtca gctgactaaa agaaaagacg tgttgcttgt ttattcaagc
     2101 aacacgtctt tcataaccaa gtttccaatt atcttcttgg ctcgtcatct tcgaattctt
     2161 ttctgaagta tcttcgttct tcttcaggtt ccgcttctgt ttcttccgga tcatgaaaaa
     2221 tgacacggat tttaaggatt cgagaacctt ccatttcttc agaaaccagc gtaatattat
     2281 cgacatcaaa cgataacttt tcgccttcat ccggaatcat gcctaatgct gtaatcaaat
     2341 aaccagccat cgtatctaca tcactcatat gcagatcact gtcaaaagct tcattgaact
     2401 catcaatcag catacgtcct tggatgatat attcgtgttc atcgattttt tcataaagat
     2461 tctcaacttc atctgattca tcatcgattt ctccgacgat ttcttctaaa aggtcttcta
     2521 gtgttgctaa cccaacgacg ccgccatatt catctaataa aatagccatc tgattctgcg
     2581 tctttttcat ttcatataac agatcatcaa taaagaccgt ttcaggaacg aataaaggct
     2641 cctgcatgat tttcttgata tctaaattat caaagccgaa tttatgggca gcttttagta
     2701 aattctttgt atgaaggatt ccgactactt tatctttgtc ttcgttataa acagggattc
     2761 ttgaatagtt ttcggataaa acttcattca cattttcttc cacagtgtcg ttgatatcaa
     2821 tcataaatgc atccgttcgt gggaccatga cttctcgggc aactttcgta tcaagagaaa
     2881 aaaccccttg gagcatttct aattcttcat tattcaatac gccttcgttt tcaagcatat
     2941 aacgcatttc atctctggtc atttttgaat cttcatcatc aaaagtcatc ggcgtgatac
     3001 gcgccaataa acttgtggaa gcagaaagca gccagacgaa gggcttagct actacaccaa
     3061 tcaagcgtat cagccctgaa gtgaactttg cgacttcttc tgatttattt aaagcaatac
     3121 gtttagggta caattctcca aaaacaatcg atacataggt caaaatagcc agcacaatga
     3181 tatttgcaat attttttgcc gctgtgccgc cacctaatac cggagctaac cgttccgata
     3241 aagtattagc tagtgaagca ccagacaaaa tgttgaccaa agtgattcct acttggattg
     3301 tcgataggaa attatttgga ttctgcaata tttttaaaag cttttgagat ttcacatctc
     3361 cttcatcagc tttttgctcg attcgattct tattgatcga aacaacagca atttcggaag
     3421 ctgctaaaaa agcattgatc aatgtcaaaa cgatcaataa taaaatctgc gctaacagcg
     3481 actgactctc agggtcagca ttcataatcg cattctctcc ttataaaatt aatttttagt
     3541 ttacgataga aaaaaacgtg gcactatagc cacgttaaaa tggtatcaca aagcaatttt
     3601 ctttgcaata aaaacaagtg tactaaaact acctacgagg tcgtagcaat tttcttcttg
     3661 ttttcatttt gcttgtcttc tttgacgatt ttgattatat aggaaatgat cgtcttgcag
     3721 attgcgtaaa aaggaacacc taagaagata ccaagcaatc cggcaatatt tccagctact
     3781 agaagaacga taatgatcgt taatggatgg attttcagtg atttcccaat tacattagga
     3841 taaatgatat tcccatccaa ctgttggacg attagcacaa ccacacaaca aagtaatgct
     3901 tttaccggat cattgaagac tgttactaga aatgcaggtg ctagtcctag ataaggtcct
     3961 aaatatggaa ttaggtttgt caatcccgca atgaccccaa ataagaaagc ataatccaca
     4021 ccaattacca tatatcctaa aaatgtgaag gtaccaacga ataaacattc gattgcttgt
     4081 ccgctaatgt aattagccaa tgttttattc agttgcccca ataactccac aatttggttt
     4141 cttctttttt ctgggaaaaa ctgttggatg tttggcacta gtttttctcc gtctttcaac
     4201 atatagaaca agatgaatgg tgctgtaatg attactacgg ttgccgaagc gatcgttcca
     4261 acgatcgaac ctaaactatt ggatactcca ctaaggaatt gctgaatgat tgtcccgtaa
     4321 gaaatgtcta attgctcaaa atatttattg atatctactt ccttgaacaa aggcaattcg
     4381 gctacctctt ttaaccagct ttctacctgt ttgatgaaat caggcatatt agatgccaat
     4441 gaggaaattt gctgtactag acttgggatg acactaagta aaatccaaat aattgctgca
     4501 actaaaagga gcagcacaat tgcgacagcc catattcttt tgatttttgc tttcatcaac
     4561 agcttgacaa taggattcaa taaatagtaa agaaagcctg caatcagtac aggtgcaaat
     4621 aacgtggaaa aaaatgtccc gatcggttcg aaaataaagt ttatttctga tgaaatcatg
     4681 atcaatgcag ctatgatcaa taattcaagc gaccaaaaca ttagtttaga ctgtctaagt
     4741 ttttcaaaca atagatttcc tcctttcttt cttactagta tatattatat tcgttaaaaa
     4801 ttcttttatt ctttttttat ttttgaaaac ttgccatact ttttatttgt tttattttcc
     4861 agtatactat acgaaaggaa ggtggctaga ccatgaaagt tgtacaaaca aaagatacaa
     4921 tgagcaatat ttacttagat gctgtacgga tcaggcatca agtttttgta gtcgaacagg
     4981 gtgtgccttt gtctcgagaa atagacaaag atgaagccca ttgtatccac ttcgtcctgt
     5041 actcagataa aaaagaaccg caaggaactg tacgtctttt gcctttagaa aacggaaaaa
     5101 tgaaattaca gcggatggcg attctttctg aatacagaca ccaagggtta ggaaaaatat
     5161 tgattgaaga agcagaaaac tttgctaaga atcaaggcta taatacgatt ttattagggg
     5221 cacagtccac agctgaaact ttttacgaaa aactaggata tacagcttac ggcgatcctt
     5281 ttgaagatgc tggcatgcct catatttata tgaaaaagac tttataaaaa tttatttcga
     5341 aaaaagcaaa aaacagcaag cttttgagaa aaatctctca ctggcttact gttctttttt
     5401 gtgtttactt acgcgacaat tgcttgtaac ggttatacca aatatcaata tagccttccg
     5461 agaacgggcc atctccatta ttgatccagt caaccagaat cttcacattt tcttttagga
     5521 tgaagtcaat atcgttcggg taattcatca ttttgctgtg catctcatat tcatcgacat
     5581 ccaatagtcg tttctcgccg tcaggaaata ccttgatatc caagtcatag tcgatatatt
     5641 tcaaggcctc atcgtccagc aaaaaaggtg aagctagatt acaataatag gaaaccccct
     5701 tttctctgat cattgctatt acattgaacc agtatttttt atgaaaataa acaatcgctg
     5761 gttcgcgcgt tacccatcgg cgtccatcag attcagtgac taatgtgtga tcattcacgc
     5821 cgatcataga gtgttcgctt gtttttaata ccatggtatc tcgccacgtt cgatgcaatt
     5881 tgccgtcgtg cttgtaactt tggatcgtca caaactctcc ttcttttgga actcccatag
     5941 caacccttcc ttaagcagca ttttgtgctt tgtgtttggg tgttcattac accgacatca
     6001 taattattat atcaataaaa atgagctttg cctagaaagg attcctattg tttcgatttt
     6061 tctctaactg atctaccagt ttcatttgga ccttaggaaa aacgaccgaa tcaaatgcat
     6121 caggcttcaa ccacttcgaa gttttgttct cggtaaattc ttgttctgct ccctcggttg
     6181 cccgtccgta aaaaaggaga acatgccatt tcagatgact aaaaatatga gtaacttctc
     6241 ctaaatgtcg tgtctgccaa acaaagagtt cctgcttttc aaatgggaga ttttgctctt
     6301 cttctgctac taggtcatca aacagatcga tttctggctt tgtttcccat tcttttttca
     6361 atcgctcata ctcctcttgt gtcacttcca tcattggaaa tgtccacata ttcgccagca
     6421 atttttggct atctctttct tcaaaataat acgctccaga atgattttga agagctgcac
     6481 tgatataata aacgtctttt ggctttgctt tttttgtttt tacaggaaaa ctcgtttgga
     6541 ttcctcgttt gttagctaaa caaaaggctt ggatcggaca agtctcacac tttggagaag
     6601 ttggtgtaca gatagctgaa cctagatcca tcattgcttg gttgaattca cctggatgct
     6661 tttcatcaat gattttccgc atcgcttcat caaagatttt cctgctagaa gcttttgcga
     6721 tgtctgcttc aatgcaaaac aatctgctga ctactcgcat cacgttgccg tcaactgcag
     6781 gttctggaag tccaaatgcg atacttgcaa tcgcgcctgt cgtatatggt cctattccct
     6841 tcaatgagct aatttcttca ggcgtttgcg gcatttcccc atcaaattct gacatgatct
     6901 gtttagcagc agcttggatg ttccgggctc ttgagtaata accaaggccc tcccatgctt
     6961 ttaaaagctt ttcttctgga gcatttgcta gctcttcaat tgtaggaaac cattccatga
     7021 aacgataaaa ataatcgatc actgtgtcta ctctggtttg ctgaagcatg atctcagaga
     7081 tccagatacg ataaggatca cgattatagc gccaaggcag gtttcttttt tcttgttcat
     7141 accattgaat gaactgatct tgaaattctt ttgtttcttt atctgtccat ttttcccatt
     7201 ctttattcac tttcctcttc cttttccgta atgaatcgct ggatcatatc caaatcaaat
     7261 cctttttgat ataagctttg ctttactttt agatttcttt ttttaggttc aaaccttaaa
     7321 tttcttcgcc atagtttatc tccttgtttg actaaataat catattctat ttcttgatct
     7381 gcttcttgcg gaagatcagc tatcgcttgt tggatcactt cttgagaaaa gcctttcgtc
     7441 atcaatgttt gttggatttt tctcaataat tctttttggc tttttccgtg attttttcca
     7501 aacgcttttt cggctgtctg atgtgcattt tgaacttggt cttcaaatgt atattggctg
     7561 agcgcttgtt caatgatttc aggtttcaaa cctttttgct gcatctgctg cgctaatttc
     7621 tttggtcctt tgtcacttaa gcgcatattc gtgcgcacat aactttcccc atagaccaaa
     7681 tcatcgacaa ggtccaattc ttttaagcgg gctacgattt tatttcgatc ttcttgaagg
     7741 atttcctttt cttttaagta tgttcggatt tctttttccg atcgcaactg ataacttaag
     7801 taattcattg ctaggtgaaa accgaaatca gctccgctac tcttcttgat ctcttggata
     7861 gtttcttcgt ctaattcccg tccttttaat aatcgatagc gtactaatac atcttcagat
     7921 acttgtaaag cttctccttc agataaatct acgcgataga aagggccttt gcctttactg
     7981 attctcgtaa cggttaacat aaacatcctc ctcgaacata tattctctat cataccacag
     8041 aaaatccccg taatcaggta ttatatgtta gaataaacca cagaaaaaag aaaaagggag
     8101 atacttatgg cagaaacaat tgtcaaaact ggacaaacgg ttcctttgaa aatcaagcgt
     8161 ttaggcataa atggtgaagg aatcggttat ttcaaacggt tgatcatatt tgttccatat
     8221 gcactaccaa aagaagaagt actagtgaaa atcacgaaag caactcctcg ctatgcagaa
     8281 ggagaattaa taaaagtcaa aaaaacaagc aaagatcgcg tagtggcacc atgtcctgtt
     8341 tactatgaat gcggtggctg tcaattacaa cacttagctt atcaagctca attggatttt
     8401 aaaaaggatc tgcttttgca agcattggaa aaattcaaac cagcaggctt tcgatcttat
     8461 caacttttgc cgacgatcgg gatggatgag ccttggcatt atagaaacaa agcacaattt
     8521 cagttacgaa aaaataagca gactcaaaaa attgaagctg gtttatacga agcaaactct
     8581 catcagttag tccctataac agactgcttg gttcaagaac ctcgaacaca aaaagtaatg
     8641 aatactgttg ttcaactatt gaataaattt gatgcaccca tctatgatga acggacaaac
     8701 agtggaatct tccgcacaat catggttaga atcggtgtta aaactgggga gttacaagtt
     8761 gtttttatta ctcgcagtaa aaaattcccg caaaaaaacg caatgatccg tgagatcaat
     8821 gaacgactgc ccgaagttgt ttcaatcatg caaaatgtcc aggcacaaaa aacgtctctc
     8881 gtgatggggg atgaaacgat ccacttatgg ggaaaagaag ccattgaaga acaaatcaat
     8941 gaagtgactt tcgatctttc tcctcgtgcc ttctttcaac tcaatcctca gcagaccgaa
     9001 ttgctttatg gcgaaggaat caaagcatta gatgtccagc ctaatgaaac gatcgtggat
     9061 gcttattgcg gagttgggac gatcggctta agtgtagcaa aacaagccaa agaagtacgg
     9121 ggaatggata ccgttcctca agcaatcgct gatgcaaaaa aaaatgcgga aagattagga
     9181 tatcacaaca ctcgatatga agtcgggaca gcagagcaag ttctgcctaa atggttgaat
     9241 gaaggttttc agcctgatgg tatcatcgta gatccaccac gtacgggttt ggataacgca
     9301 ttgatccaat cattattgaa ataccctcca aaaaaacttg tttatatctc ctgtaatgtt
     9361 tctacacttg ccagagatct ggttaattta agtaaaaagt tcaagattga atatttacag
     9421 tccgtcgaca tgtttcctca gactgcacgt tgtgaagttg tcgtgaagat gacgagactc
     9481 gctgactaaa tgaaagaggt tgtgaaaaag tctgccctgt atcaagtaat aagaacagcc
     9541 aaacaaaaat agctcttcat gttttatgaa tactgtactt gtgaccgaag agttaacagg
     9601 aggacactat ttatttaaaa aaagggttgt gacatagttt ttgtcacagc cctttttgat
     9661 tattattgga tattcacgtc tatcacttga taaaatgcat ttgtcgtatc gctgatattc
     9721 catactgcta aaatcacatt atatcctttt cgatcctgcg gaagtgtgat cgtttggttg
     9781 actgtttttg gtggaacagt tgctttgtcg tctatttttg tgatcaattc aaaatcacta
     9841 aatttcaaag gttgattagg attccaagtt ggtttggtaa tgtagtaatc ccaagtactt
     9901 gtccgatgtt gtgctgttaa attccaagta atatttaatg ttcctggatt aaccatgttt
     9961 ttatgccatc tgttagatgt ctgttcatct aaaggctcaa agccgctgac tcctgcacta
    10021 gcaatttttc catcaatgaa tgtatttttg gtagcttcga tactttgcgg ttcccattgt
    10081 gctcttccga cattttgatt taagtttcct gctgctgatg ttcctaggta tgcacggctt
    10141 cctggagaag taatataacc atgcgcaaaa cctggaatgc taaaaccgaa caaccctaaa
    10201 ctaactaacc caataaacaa taacgtacta atctttttca tgtagaaacc tccttcattt
    10261 gataaccaca ttgtaaacgc tttattgtat taacacaaac attatgcttt tataatttta
    10321 tgttgaagta aaaaaggtga aaaaagtaag atgcagatta taacagaagt agacgagaaa
    10381 agtacaaata gaaaacatga gaatcaaatc atatgatctt tttcaaaaac atcattcata
    10441 taaacaaatg ttcaactttt taataacaac aattatcaat ttttttctta cttcacaaac
    10501 taaatacagg tcttgctgtg agccttcatg gtaaactaat attatagaaa ggagttagta
    10561 aaatgaagat gataaaagat attcgttttt gggtttgtgt tataggaatt gtcatattag
    10621 gctttttatc agggttgctt agcggaaatc ccggaaaata ttactattct ttgcaacttc
    10681 caccatttgc accacctagc tggatatttg ggccgatgtg gaccttactg tatatattga
    10741 tgggtatttc tctttatttg ttacttaatc acaacaacaa aaaacagcga aacaatcttg
    10801 tcggtctttt tgtgattcag ttcattttta attttatatg gtctgctcta ttttttaatt
    10861 taagaaatat tttcattgca gcaatcgata ttacactttt agttattttc ttgtcagtgc
    10921 ttatgtatca gttgtggctg catcatcgcc tggcaatgtg gctcatgatt ccttattatt
    10981 tatgggtact attcgcaact ctattgaatt attcaattta ttttttaaac taagcgctaa
    11041 aaagagacgt cctgtaattt aacacataga aaaagtgcca cctaagttag attttttgtc
    11101 taatttaggt ggcactcttt attaaccaaa ctattttttt ctagtaccca cttgttgttc
    11161 catactcatt attctggtca taaccataac cattttgttc ctgtccagcg taaggatcat
    11221 aactttgagt atcttgactt ggtgtatagt actgacttgt atcttctgtt tgctgataat
    11281 aggtattcgg atcttggtac tgatcatatg tgttttctga ataggaagaa taatcggtgt
    11341 acccttcact attcgatcca tcaccgtttg tcgaatcgcc atcttccgaa tcatcaaaga
    11401 acatcattga agcattctca tttttcaaat taggtaatgt atcgcttgtt tttatattta
    11461 attgtttctt cagttcattt tggatcgaaa gaagatcatt ttttcctaaa atttgatagt
    11521 agatatcatt gatcatttgt ccttcgcctt gcaactggtc ttgtttgatt gtttcaaacg
    11581 ccggggtgta gttcgtcgct acatcaagca tgtcatccca atctaagtcc gtcgtcacat
    11641 tgttctcaac tgcttttaaa atttttctat aattgcttac gccatctaaa cttaaaactt
    11701 tattgacgat tttcgtcact acttcccgct gacgacgttg tcgaccgata tcgccttctg
    11761 gatcttcgtg tcgcattcga gaataggcta aacctttttc tccattcaat gtttgttcac
    11821 ctactggtac atggacacca tccaaagtaa agtcaatttt attattcact ttgatgccac
    11881 cgaccgcatt gatcaaatct tccatgccat ccaaattgat cgttacataa tgatcaatag
    11941 gaatatcgag cagttgctca attgaatcca tggccatttc gacaccacca aatgcgtagg
    12001 catgatttaa tttatctacc gttccataac ctacgatatt cgtataaata tctcggtcca
    12061 aactgatgat cgttgatttt ttttgtttcg gattaactgt tactaccatc atcgtatcag
    12121 aacgtccttg ttccgttctt cctaatccac cggtatctaa acctaatagc aaaaccgaaa
    12181 aaggttcttt gtcatcaatg cttactctct cagaacgttt ggaggatatt cgattagagt
    12241 ttttagaaat tttgtttact gtttggctcg cttctcccat aaatctgatt ccgtatgctg
    12301 ataatccggc aatcagcaaa acgaataccc ctaacaaggt taatagaact ttttgccatc
    12361 gcttcataat acacctctgt ttcacatttt ctaaaatatt gtctcatata actgttcaat
    12421 cagcaaattc actttttaat cataagaaaa ctttaaaaaa catttttgtg taacgattat
    12481 tattttttaa aatttctcaa aattcttaac tatcatacca taccgtgaaa aagatcgaaa
    12541 gaccgaatac acgcagttcg caatcgtttt atcttttttt atgtattttt tccagaaaaa
    12601 gcgaacaaca aggtattttc caaataatcg tgcagtaaaa tgatcgcaca tacctttccc
    12661 atctttttaa cagtctttgc ctaccgttca gattatcatt cgatttcacg acaatttctt
    12721 cctatgactg gtccttttgt taaacccatc ttctattcgt tttatttcca gctcactgca
    12781 tggctcttaa aatgactcga actagtgatt gcattaccat catcttttaa tggatagata
    12841 tgctcctctt caaagtaaaa cgattttctt ttaaagtaat agaattgaca tggtaatgag
    12901 tatgtatact agtggtttca caaatggtct tttattcaac atccaaaaac tgaaatttct
    12961 ttaaaatcca ttactaacga agaaaatgtt ccttgcttga taattagtta ggacatgtca
    13021 agtgaacaaa tgcatttact tagccaaaa
//
LOCUS       DAFEIE010000073        12597 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFEIE010000073
VERSION     DAFEIE010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.076"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(10..159)
                     /locus_tag="LP345_002331"
     CDS             complement(10..159)
                     /locus_tag="LP345_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761093.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            555..755
                     /locus_tag="LP345_002332"
     CDS             555..755
                     /locus_tag="LP345_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1761094.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            1323..1886
                     /locus_tag="LP345_002333"
     CDS             1323..1886
                     /locus_tag="LP345_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761095.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1947..2291)
                     /locus_tag="LP345_002334"
     CDS             complement(1947..2291)
                     /locus_tag="LP345_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761096.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(2388..2633)
                     /locus_tag="LP345_002335"
     CDS             complement(2388..2633)
                     /locus_tag="LP345_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1761097.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(2703..2957)
                     /locus_tag="LP345_002336"
     CDS             complement(2703..2957)
                     /locus_tag="LP345_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761098.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(3121..3444)
                     /locus_tag="LP345_002337"
     CDS             complement(3121..3444)
                     /locus_tag="LP345_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761099.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            3631..3704
                     /locus_tag="LP345_002338"
     tRNA            3631..3704
                     /locus_tag="LP345_002338"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3665..3667,aa:Ile,seq:cat)
     gene            complement(4089..4586)
                     /locus_tag="LP345_002339"
     CDS             complement(4089..4586)
                     /locus_tag="LP345_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1761100.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(4626..5435)
                     /locus_tag="LP345_002340"
     CDS             complement(4626..5435)
                     /locus_tag="LP345_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1761101.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            5769..6626
                     /locus_tag="LP345_002341"
     CDS             5769..6626
                     /locus_tag="LP345_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL1761102.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            6619..7521
                     /locus_tag="LP345_002342"
     CDS             6619..7521
                     /locus_tag="LP345_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL1761103.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            7554..7904
                     /locus_tag="LP345_002343"
     CDS             7554..7904
                     /locus_tag="LP345_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1761104.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7953..8876
                     /locus_tag="LP345_002344"
     CDS             7953..8876
                     /locus_tag="LP345_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL1761105.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8954..9847
                     /locus_tag="LP345_002345"
     CDS             8954..9847
                     /locus_tag="LP345_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1761106.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9885..10448
                     /gene="amaP"
                     /locus_tag="LP345_002346"
     CDS             9885..10448
                     /gene="amaP"
                     /locus_tag="LP345_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL1761107.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            10462..10650
                     /locus_tag="LP345_002347"
     CDS             10462..10650
                     /locus_tag="LP345_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL1761108.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            10663..11565
                     /locus_tag="LP345_002348"
     CDS             10663..11565
                     /locus_tag="LP345_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1761109.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            11597..11839
                     /locus_tag="LP345_002349"
     CDS             11597..11839
                     /locus_tag="LP345_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1761110.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(12095..12466)
                     /locus_tag="LP345_002350"
     CDS             complement(12095..12466)
                     /locus_tag="LP345_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761111.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4461 a         2113 c         2366 g         3657 t
ORIGIN      
        1 ttccactcct tatgcagatt tttttaattc ttgcactgct tgttcgatcg taacacctgt
       61 cgctacatga ttggtatttt ctttgtcaaa aacgacaaat agattcaaat ctgtatccaa
      121 ggttactcga tattgtatat ctttgttata gaatgtcata gccattctcc tttctttaaa
      181 tacttgctga aaggcaacga acgcgttgat aacgaaattc catttataag tataccacca
      241 attgaaaggt tttcatagtt aagaaatttt aaagtcaaaa gttgcagata aaagcaaata
      301 aacaagaaaa caaaaagtga atcaatcgcg gttattcaac tttttcttcg attcgaagac
      361 aatagaagac aatgaatttt atatttcatt gcattatcct tgtgttatta gaaaaagcat
      421 gatatattaa atgagtaatc tattttgaaa cgtaatttga gcgatatatc tacatagata
      481 aaactccttt tgcctatcaa atatttattg caacgaaaaa acgtacattg atacgtatca
      541 ggaggaattt atttatgaat aacggtacag taaaatggtt caacgcagac aaaggttttg
      601 gctttatcac tggtgaagat ggaaatgatg tatttgcaca tttttcagct atccaaggtg
      661 acggcttcaa aactttagaa gaaggccaag cagtgtctta cgatgttgaa gatggtcaac
      721 gtggccctca agcaacaaac attgttaaag cttaataaaa attgactttt aaccgtcttt
      781 tcgaaagaaa agacggtttt tttgtacgaa aaaattcatt ggtcgttgaa tgggctgaat
      841 agtagtgtat aaaacaattt tgtggagcgt gaagctttta tggtagagga aaatacgaat
      901 aaagtgatgt tgataaaaag attcctatct tgaatatgaa tcgagatgtc ttgaaaatga
      961 atgagtttga ccaatcatta tcctatcgaa atttacagtt tcgttcgatt ggtctgtcaa
     1021 ttaatgaaaa agtaaaaaag aatatgttct aggaagaggg cggcacatct aaatttttaa
     1081 gtaacggaca gttcaaatat caagcattga aagaggctat cctactgttt gaaggaatac
     1141 gaatatataa aaacgacaaa gaggaaaaag tagttcatta aatcccttca agtgatgaaa
     1201 gaatgagatc taataaaacc tgatctttca tctgtttttt taataacgta ataatttttt
     1261 tattttttgt gctttcgccg ttattgtaga gtgatttagc attcttattt ttaaaaataa
     1321 ctgtgttata tattaaaaaa ggcataatag ttataagctt ttttaaagaa tatttagaaa
     1381 ttattaattt tcgtctgaaa acaaaaaaag aaagcgttat tattttagtc tattttcagg
     1441 gggggaacct tatgataaaa aaactatttt tactatcaat attaacgcta gcaatggcag
     1501 gttgttctga ctctggctta gcaactgaac tgatcacaaa atcaactgaa gccacgacag
     1561 aggagttaaa atgtggaaac gatcacagtg actacagagg cttaaatcga cgatgcatgg
     1621 gaatattagg cagaagcaat tgtaagcatc gatgtagtaa tcgaagaagg tgtagaagaa
     1681 gcaacagaaa aatcaaaaga aagatcaaaa gaagcaatct gtgctgtgca tcgtatacag
     1741 acgtcgaaga tgcggtactt ttaaaccacg tcaggagatg ttcatttatg tctagggaag
     1801 ttggcgatga accaaaacta gagtacgctt ttagttttgc acgtgaggat gaagataacc
     1861 ctaaaactta cgacatttta gcttgatcta agatggttaa agctttttaa tgaagtaaga
     1921 ggagatagaa ggcttttcta gttatattag gtaagataaa ttcctttttg ctccaaattt
     1981 gctaaacatt ctgctagata aacttcatcg tgttccggat aaatcggcac gttgcgctct
     2041 acagtaggta aatcaaaaaa tgcttcgcat gatttgccac gatacatagg atttttccac
     2101 tctggtgctg ggctgtaacc acgtttttcc atttcatcca tgacaagctg atgatattgg
     2161 aataatctat aaggagaata gtgaaaaaca taatccacag tagcatgttt ctttccccag
     2221 ccatttcctc ttaatgcaca gcattcccga tgttgtccta aaagctgttg acgaggaagc
     2281 tttgaaatca atttttcatg ccataatcac atagaaatgt ctcctttata tatagattgt
     2341 taaccttaga cgttaaatga aaaaaccagc accaaggctg gaaaaaatca cttcagtttg
     2401 cttgctgttt ctgagcgacc aattaggtaa tcaacggaaa tatcgtaaaa gtcagcgata
     2461 tagattaatt caatgatgct tggaatttct tctccttctt cgtacttacg atatttgaat
     2521 aaaggaatac ttaacgcgct agaaacagct acttgagata aagatcggcc agttcttaag
     2581 aaattcagac gacaacgtaa agtatccagt aaaatagctt cttcgatact catttaatca
     2641 cctttcatta tagtagaata gttataatga ctatagaaag ctacacatgc aatcaatagt
     2701 actcaatgtt ttttatttaa acgtatcaaa taaagaatga cgatcaataa agacaaaacc
     2761 agtcctgata attcttctat aaaaacacta tcgggttcaa agtagttgta attaaaaact
     2821 ttccacataa agtagatagc cggaagagtc aaaatagcta aataaaaccg ttctttgttc
     2881 caattcataa gataaacaat acttgcgacc agtgcgaccg caggcaccca aaacaaaact
     2941 ctcaccaacg taatcatgta acggactcct caacgattca tataataaaa gataacatgt
     3001 tattgcatac atcacaaatg aaatgctagg aaaataaaag aagaatagat caatgaaaaa
     3061 tgaaaaagca gaacagtttt ctgctgataa gcaggaactg ttccgctgaa tgtgtcttat
     3121 ctatcgagaa aaaatcaatg gattgatatc taagtaattc aatacatata aaaagaggac
     3181 gatcgcattc actaaaaagg aaagaatgat gatcccatag cgaatggaaa catatttaac
     3241 aaatactttt gtttgaatac gggcatatct ttttccttta tagctgagca tcatgacaag
     3301 aagcaaaagg gtaatcacac cttgaaaaat cattccaata aacagaattc ctgaggtttg
     3361 ataatttaat tggagaaaat aagctgctgc cgcaactaaa tcgaataaaa tcgcaataaa
     3421 tggcaaaata atcactccta acattgagaa taaataaaag aataacattt tttctaaaat
     3481 aagcaaataa aaattaaagt aacaaaatag ttatgacaca agtaaaagaa ataagaataa
     3541 caatattatt ttacttatat tttgaaactt gtgagagttt gtcattcgtg ctatagttga
     3601 aaagtaacaa aaataaattt tatttatgat gtacctttag ctcagttggt tagagcagac
     3661 ggctcataac cgtccggtcg taggttcgag tcctacaagg tacataagag gttgtgaaaa
     3721 agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttact
     3781 tggctgttct tattactgca gatgcaagct tttgaatacc gtttaaggaa gaggttgtga
     3841 aatcagcgtt ttgacctgag tattagctta acaaacggaa aaatagttcc tcatattttg
     3901 ccgtttgtta agctaatacc gagggtcagc tgattgaaca ccatttaaga aagaggtcgt
     3961 gagcctgccg tttcactctg tgtcataaaa aagccaatct actttgatag aaaaagcacg
     4021 taggactaaa acagttctgc gtgctttttt tattgtgtgt taaatatcgt aaatgaagat
     4081 agatattttt atgattcgac gatagagacg ttgaaatctt tcaacagctc taaagcggat
     4141 tctccgtgtt ttctactgga gactaacatt ggatcaacaa aaaagtctgc ttcaggaaaa
     4201 gcactctgca ggcctatcag attagagagt acacacaagt ttgtttcaat cccgactact
     4261 tcgatctctt tttgttcttc tttgctttca aataaagttt cctggatttc agctaaagtt
     4321 tcaggtggaa tcgtaaagta atacttttta atcactcgtt cattttcttg tggagaaaga
     4381 agagggatca attgcaaatc ttctcgttct tcttctttgt ccttcagttc aactggtata
     4441 tcccgtgtga agagaatata ttcattattt tggcgtgctt tagctaatct ttgagcaata
     4501 cgttctgcca attgatctga ctctggaata taaaattcgc tgtttggatc aagaatatga
     4561 ttttgcatat caataataac taacattttc tttcctccta cattcatatc gtcattttat
     4621 tctttttaat agaagttttt taaaatataa gcaacaccag cttcttcatt cgtcagtgtt
     4681 acttggtttg caatttcttt tacttgtcgc tgtgcattcc ccatcgcaat actcaacccg
     4741 ctgtaattca acatatcaat gtcgttttct tgatcgccaa aagccatgat gtcactcgat
     4801 tcgattccaa ggtaatccgc cagaaaaaca agtgaatgag ctttagtgat acctgtaggc
     4861 gtgatttcta agaaatgcgg atcagagaat actgattgga taccatctgc ttgcagatct
     4921 ctttgtagct tctgtagttt ttcttcactc ttatctgtta atgctaattt aagatagcta
     4981 agagaaggat cttccaacat atttaaaatt tgatcaaaag aatggttctg taaattgaaa
     5041 tgttcataat aagggtcatc tttgactaga tttgattcat cgaatgtcag ctgatcatct
     5101 tgggtttctc ggctagcaat gatggatatt ttcgcttctt gagcatagaa gaaggctttt
     5161 ctcagtgtat cgctatctat ttttgaacgt ctgagaactt tcgccatttt tccatccttc
     5221 atttcagcaa tcagtgaacc attggaagaa atcaaatagc caccgattcc taattcggaa
     5281 aaaatatctt tagcagaaat gctgttcctt ccggtagcga cggttacgat tccgccattt
     5341 tcatcaaatt tccgaagtgc ttggatattt tcttctggta tctttccatt tcgatcaagc
     5401 aaggtaccgt ctaaatcaat cgctgctagt ttcattttat cttcctactt tctttttaca
     5461 tatctatttt cctgttacct taagattaaa tgagaattta aaaaaatgaa actaacttgc
     5521 tttgtcatta tgaatttttt caaaaaacat tcttaagaaa aaggtggcta tatatagtag
     5581 tttttggtca atacctttga ataaaaagcc atgaaaaacg aatagttagc gcttaccgat
     5641 gcgttttgtg ataaaaaaat tttaaaatat tcaatgaaaa caaagcatat attttgcttt
     5701 aaaaccaaat gaggaatatt ctagatgtag aacaggttag aaaaagatta gaaaaaggag
     5761 tgattttgat ggagaagaga tacggcgtag ttcctgtggt aactgcttca gacgaaaatt
     5821 atgctcctta cttgagcgtg atgatcgcaa ctgcattaga aaattgcaat aaaacaagac
     5881 gcataaaatt ttatgtgatt gacgatggtc tatcagaata tagtaaagaa ggattggaag
     5941 aaacggtaaa taaatattca agtaatgcaa gtatccaatt cctgacagtg gaaaaagata
     6001 tctacgaaga cttcctagtc agtgaccata tcacaactac cgcttactta agaatttctt
     6061 taccaaactt attagctaaa gaggattata agaaagtcct ttacttagat tcagatgtgt
     6121 tagtactaga cgatatcgta aaactatatg atgagccgtt aaatggaaaa acaatcggcg
     6181 ctattatcga tccaggccaa gtgaaagctt tggaaagatt aggaatcgat tccgatgact
     6241 tgtacttcaa ttcaggagtg atggtgattg acattgatca atggaataaa aaagaaatta
     6301 cagaaaaaac tatccattac ctcagtgaaa atggcgatcg aatcatctat cacgaccaag
     6361 atgctttgaa tgctgtactt tatgaagatt gggaacaact tcatccaaaa tggaacatgc
     6421 agacttcgct gatttttgaa cgtcatccag caccaaatga aaaatatgaa cgtcagtata
     6481 aagaaggaaa tgaaaaacct tcgatcgttc actttacagg acatgataaa ccttggaata
     6541 cgttgaaaga tcatccgtat accaatttat acttaaaaaa attagcacac agtactctaa
     6601 cgaaagtagg cgagatcaat gaataaaaaa gaaatagcag tagtcgcaag ttgtaacaca
     6661 aaattcgtac cacatttagc tgcattattt gtctcagtat tagataattg caacccgtct
     6721 aaatttgttc ggttctatgt gattgacgat gatatcgatt ttgaaagtaa acagctttta
     6781 cgcttctcag tgaaaaacgc acgaatgaac tcagatgtgg aattcttgaa aatcaataaa
     6841 gaattcttta caaatgtggt aatcagcgat cgtattccag aaacagctta ttatcgtatt
     6901 gcgattccgg aattgttccg cggcacagaa gttgaacgta tcttatatat ggattgcgac
     6961 atgatcgctt tacaagatat ctctaaatta tggcgtcttg acttcggtga ttcaatcgta
     7021 gcagctgttg aagacgctgg gttccatcaa cgactggaaa aaatgaaaat ttcagctaaa
     7081 tcaatgcgtt atttcaactc aggtttgatg ctgatcaatg tgaaaaaatg gttagatgaa
     7141 aatattacgc aaaaagtatt agatttcatc gaacataatc cagaaaaatt acgattccat
     7201 gaccaagatg cattaaatgc tatcttacat gaccgttggt taccacttca tccgcgttgg
     7261 aatgcacaag gctatatcat ggcaaaagca aaaaaacatc caacagcagc aggtgaacgt
     7321 gaatacgaag aaactcgcaa caatccttac attatccatt tttcaggaca tgtgaaaccg
     7381 tggagcaagg attttgaagg gccaacgaag aaatattacg aaaaatatgc agggatgacg
     7441 gctttccgtt gtgtagctaa attccctaaa tatccaaaat atgcaaaagt tcaaccaaaa
     7501 acagatgtag ttgttaaata atagaagaca acaactgaag agggggagta ggaatggaaa
     7561 ttacaatgtc taaaaatgca gtagagacgt taattgaaaa ggttggggaa aatacaaaaa
     7621 tcgcactcgc gcttatcaat gattccgatc catttctaag ggacaaaggt gcttttgcaa
     7681 aaggcagctt ttttcaaatc attccttttg tttcggaatt tggagaatat gcgactaaaa
     7741 tcgagcatcc attattggac atctatacat ctaaattaga gcaaaattat ttcggtaaac
     7801 gattgaacat ggacttcaac aaacagcttg acagcttttc attagaaaat gaaatcgcag
     7861 tactcgatta taatatcaaa ttaaagaact gcttcttcag ctaatagttt cgagaaagtc
     7921 caaaaaggag gtatacattg agatactact ttgtggatga agaaaagaat gtaatagaaa
     7981 cagatgaaaa aaaatataat tggctcgtac ttgatagtgc aaagcccgaa gagattgagc
     8041 aagcaatcga agaattcgag cttcctgatg atattttcgt aggaaccgaa tatccggaag
     8101 aagtttctcg gatggagcgc ctttatgaga cgaaactaga gcatccattt tctttggtag
     8161 tgattaatct agatcagtca gataatcgta tcgaaaaaaa attaacgcca atatcttttg
     8221 tactttccga taatctcttg attacttgta tcgatagaaa aaccgaattt gtggatcggc
     8281 tgctgacaaa gcatggaaat catttaaact cgtttgaaaa gatcatcacg tatacattat
     8341 tagatattta cacccattac gtgaaagaac taagagagat gaaaaagcga attgacgctt
     8401 tggataaagc agctcgtaaa acaacggaaa atgaagaact gtataaacag gcagatcttg
     8461 aaagagacat cgtatatatc gatcatacct taagagatca acgggaaaca atggatcaat
     8521 tatggaattc tgaaactttc atcaaacgtt tagacgatga acagctactc tatgatgtcc
     8581 atttgagaca gcgacaaaca gaaaaaatga tcgagatcta tcgagattta ttagagagta
     8641 ttggtgatct attcaacggg atgatggaca ataatctaaa tcatatcatg aaatatctag
     8701 attcagctgc attaatcatt tccgttccgg cgttgttcgc agggatttgg ggaatgaata
     8761 caggaggatt accgggtaaa agttctgctc taggctttat actcgtagtc tttggctctt
     8821 tgatagcagc agtagtttta ggttaccatt tataccggaa agattataca aattaaagaa
     8881 tctatttaaa acaggtatca aacaaagaaa tttgttttgg caatacaatt taaaaactag
     8941 gaggaataca gcaatgacag aaccaaaatt aatcgacccg cgaaacttgt accatacgga
     9001 gaaatttcct aaacaagatc aggatacacc agctttacag cagaatatga ttcctgttcc
     9061 tgattgtgga gaagaatcct atgaaggcaa taatcaacta gaaaaccgcc gtgtactaat
     9121 cactggtgga gattcaggga tcggtcgtgc agcagcgatt gcatttgcta gagaaggggc
     9181 agatatcgct cttcaattct tcccaggaga agaaaaagat gcagaggaag tagcaaaata
     9241 cgtgaaagtt gcaggacgta agattgtctt actacctttt gatcttcgtg acgaacaagc
     9301 acctaaagaa atcatagata aagccgtgag tgaacttggc gggctagata cgatggtact
     9361 aaacgcagga cagcaaattt cttgtcagtc tattgctgag ttaccacttg agcaagtcaa
     9421 agacacattt atgataaaca tcatcgctat gtttgcttta gtgaaagaag ctgttccgca
     9481 tatcccagca ggaggagcaa tcgtaacaac aacttctgtt caagcattca atccaagcga
     9541 acatttatta gattacgcag caacaaaagc ttcaatcgct aactttacga tcggtttagc
     9601 aaaacagctt gcacctaaag gaatccgtgt aaatggtgta gcacctggtc caatctggac
     9661 accattacaa ctagacgaag gacaaccttc tgattcgatc cctgaatttg gtcagcaaag
     9721 tttactagaa cgtgcaggtc agccaggaga attagcacca gtttatgttt tcttagcatc
     9781 gaataaagca agttatgtta cagcccaaat ttacggagta actggtggag aagcgatcaa
     9841 cttataagaa gttgatcgtt tcacccctat gaggaggtgc gaaaatgaat aaaggtgtaa
     9901 aaacgatcgg agtgatcgga acattacttt tgctatctgt gcttttgttt gcgatactat
     9961 taagtgcaac ctatccattg ccttttcagc tagagaagtt tcgattcttt tccatcacta
    10021 attcatacgt gcaacaatat gtattttggc ttgccgttgc atttgctatt ttgacaatta
    10081 tcacgttact tgttttcctg ttttatccaa aaacaatcgg aaactttcta ctgaaacatg
    10141 gtgatgggga gttgacgttg gataaaaaag caattgaagg aatggttcgt tctcacttgc
    10201 atgaagatga attcatccat tcaccaaaag taaatgtcaa agcaacgaaa aacaagatcg
    10261 ccgtcaatgt aaaaggggag ttgaaacgaa cttcagcact cattggtaaa acaggaacat
    10321 tgatgaaaga aatcgaaaat gaagtacaac acatattggg aacaaaagag ccagtgaaag
    10381 tatcggtgaa atacacaggc tttgaagaac cagctaaacg aagcaatgac cgcaaacgag
    10441 tagaataggg ggggaccaaa aatgaaagaa ctattttcga catacaagct ccctatcatc
    10501 tttggggtac ttggattgat attagccgtt ttatggatca ccgtgggctt tttcaagacc
    10561 ttattgatct tgatcatggc agcgatcggc gtcgctatcg gtttttatct gaaacaaacg
    10621 aaaatcttag atcactattt taaatcttag gaggaaacat ccatgaataa caataacaaa
    10681 aataataaca ataaaatgaa caaccaaaaa ccagtgtctg cacatccaga cccaacgaca
    10741 ccaaaccaat caaatggtgt gaacgatgaa aagaacaaaa cagcaccagt atctgcacat
    10801 ccagatccag tagtccctaa cgttcaacaa ggagtagaag agaagaaaca tgatgcagaa
    10861 aagcatgcac ctcatcatcc aggaactcca gaatctaaag ttccagaaca acatgatgca
    10921 atcgatcctt ctaaacctgt ggaagagcaa aaacatcctt ctgaccatgc gaaagcacaa
    10981 gaaaaactta gttctgacca cacaaacgga caaggaaaac ttggttctga tcatacaaat
    11041 aaccaaggaa agcatgattc tgaacaggaa gattcaatgc gcggtgagct gaattatgaa
    11101 gataaagttg tgcaaaaaat catcggaatc gcaattgaac aagtagacgg tttattatct
    11161 gcaaacggtg gtttcttctc taatgtggca ggaaaacttg tgaatacaga taatgtaacg
    11221 gctgggatcg aaacagaagt cggtaaaaaa caagtagcag ttgatatgga tgtcattgtg
    11281 gaatatggca aagatatcga aaaaatcttt gaagaaatgc aagaagtaat cggcaaagaa
    11341 gtaaaaaata tgacacattt agaagtgatc gaagtcaacg ctaacgtagt ggacatcaaa
    11401 acaaaagaag aatttgaaaa agatcaagaa acggtgcaag acaaagtaac tgacgcagcg
    11461 aaaaaaaccg gtgaatttgc ttcgaatcaa acagataaag taaaatcagc agctggaagc
    11521 ggcgcacaaa aagtaaaaga aaatacagaa ccacgggttc agtaataagg aagtaaaaca
    11581 ttaggaggaa cgaaacatgg gatttatttg gtcacttatc gtcggaggaa ttatcggagc
    11641 aattgcagga gcaatcacga ataaaggttc ttcgatgggg attattgcaa atgtcgtagc
    11701 aggtttagtt ggatcagcac ttggtcaagc attattaggt tcttggggac caagtattgc
    11761 aggaatggca atcgtgccat cattgattgg tgccatcatt ttagtactaa tcgtatcatt
    11821 ctttgctcga aaactgtaaa aagactttta aaaagaggtc gtgaaaaagc tgttcttcat
    11881 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcatttg gttgggcata
    11941 ttatcgaaga tgcaagcttt tgaacactgt ttatacggaa taagaggctg tgacaagact
    12001 tttgtcacag cctcttattt atgcgggcaa attcccaatt agatttttaa aagtttttcc
    12061 ttaaatgtgt ctttattgat acagagaagc ttctttaata aaacaatgcc tccctaaatt
    12121 ttcttgagat aggaaaggtg aacatacaaa ataatacgac cactttgaaa acccagatga
    12181 tccacaaatg gatcgtatga tactgatgaa gtaaaaagca atggatcaga aactcaaaga
    12241 gattgaaaaa gacaaggaag aaataatatc tcttttttac tcttgtctgt tttagccaat
    12301 aatagctcgt aaagtaatct agacaaacaa atagaagtaa acaaagtttc gtaagagcag
    12361 caatcgtatc atgttgctct gctagacgat tgacgagcag gaaaaatgtt ggtaatggaa
    12421 tatagatcac gagtaatgaa agaaaaaagt aaacaataaa tggcatacta ttcctcctaa
    12481 ttgtgtgagt tcgccctcat tttaaaataa cgatatttgt ttgtgaagct ttttcgtgtc
    12541 gtaacaaatg ttatctaatg tatttttaaa taaataatca ttattatcaa aataatg
//
LOCUS       DAFEIE010000074        12163 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFEIE010000074
VERSION     DAFEIE010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.077"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..912)
                     /locus_tag="LP345_002351"
     CDS             complement(<1..912)
                     /locus_tag="LP345_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL1761112.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTA"
     gene            complement(925..1494)
                     /locus_tag="LP345_002352"
     CDS             complement(925..1494)
                     /locus_tag="LP345_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBL1761113.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(1466..2653)
                     /locus_tag="LP345_002353"
     CDS             complement(1466..2653)
                     /locus_tag="LP345_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1761114.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(2717..4444)
                     /locus_tag="LP345_002354"
     CDS             complement(2717..4444)
                     /locus_tag="LP345_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL1761115.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESSFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(4441..4893)
                     /locus_tag="LP345_002355"
     CDS             complement(4441..4893)
                     /locus_tag="LP345_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBL1761116.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(5005..5385)
                     /locus_tag="LP345_002356"
     CDS             complement(5005..5385)
                     /locus_tag="LP345_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL1761117.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(5382..5768)
                     /locus_tag="LP345_002357"
     CDS             complement(5382..5768)
                     /locus_tag="LP345_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761118.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(5770..6048)
                     /locus_tag="LP345_002358"
     CDS             complement(5770..6048)
                     /locus_tag="LP345_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761119.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            6096..6824
                     /locus_tag="LP345_002359"
     CDS             6096..6824
                     /locus_tag="LP345_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBL1761120.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(6970..7446)
                     /locus_tag="LP345_002360"
     CDS             complement(6970..7446)
                     /locus_tag="LP345_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBL1761121.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(7406..7753)
                     /locus_tag="LP345_002361"
     CDS             complement(7406..7753)
                     /locus_tag="LP345_002361"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761122.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(7740..7925)
                     /locus_tag="LP345_002362"
     CDS             complement(7740..7925)
                     /locus_tag="LP345_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761123.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(7926..8198)
                     /locus_tag="LP345_002363"
     CDS             complement(7926..8198)
                     /locus_tag="LP345_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBL1761124.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(8195..8398)
                     /locus_tag="LP345_002364"
     CDS             complement(8195..8398)
                     /locus_tag="LP345_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761125.1"
                     /translation="MVKVREQFKIVSDEDNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            8523..8735
                     /locus_tag="LP345_002365"
     CDS             8523..8735
                     /locus_tag="LP345_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761126.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(8768..8962)
                     /locus_tag="LP345_002366"
     CDS             complement(8768..8962)
                     /locus_tag="LP345_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761127.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(8970..9158)
                     /locus_tag="LP345_002367"
     CDS             complement(8970..9158)
                     /locus_tag="LP345_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761128.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            complement(9155..9295)
                     /locus_tag="LP345_002368"
     CDS             complement(9155..9295)
                     /locus_tag="LP345_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761129.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(9785..10150)
                     /locus_tag="LP345_002369"
     CDS             complement(9785..10150)
                     /locus_tag="LP345_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761130.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(10190..10492)
                     /locus_tag="LP345_002370"
     CDS             complement(10190..10492)
                     /locus_tag="LP345_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBL1761131.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(10492..10791)
                     /locus_tag="LP345_002371"
     CDS             complement(10492..10791)
                     /locus_tag="LP345_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761132.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(10784..10948)
                     /locus_tag="LP345_002372"
     CDS             complement(10784..10948)
                     /locus_tag="LP345_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761133.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(10954..11223)
                     /locus_tag="LP345_002373"
     CDS             complement(10954..11223)
                     /locus_tag="LP345_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761134.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(11235..11984)
                     /locus_tag="LP345_002374"
     CDS             complement(11235..11984)
                     /locus_tag="LP345_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1761135.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(11987..>12163)
                     /locus_tag="LP345_002375"
     CDS             complement(11987..>12163)
                     /locus_tag="LP345_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761136.1"
                     /translation="LGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGI
                     KLNQKTIKKLNIGG"
BASE COUNT         3361 a         2511 c         1864 g         4427 t
ORIGIN      
        1 agcagttaga tctaaaggtt ttttaaatgc tacagccttt ttggctaatg caccaggatt
       61 ttcatttcca gcgtcatcac cattgaacat ataattgatt tctttacgca cataagcttt
      121 tttcaattct tccacaacaa tatcttcaac tggaacacca gacattttta ataatttttt
      181 agttactgtt gccaaagcat cgaattcggc aggattaagc aaaatttcat caaactgaat
      241 agctgtttca gcaatatcag ttgaacgctc tttcttgttt acattcgcat ctgctttctt
      301 cacaagaatt ggatatttga catctcctga tgttcgcacc actgttccgt atttacgaag
      361 taaattttct tcttgagcat aagtaataac ttcagatgca attacttctg ggacagtaac
      421 tgaaccgttg ccagcttcaa tccctaaagc tcgagcttct gcttcagaaa tatttccagc
      481 tacaaaatta gcaaatgctt ttcgtagttg ttgatctttt tgtttcttgg tcatttttgc
      541 acgtgcctcc aatccgttct taattgatcc aagtaatcca tctcgttgct gttgagtaat
      601 cattccagaa cgattttctg aactatcttc actgtctgaa tcttcttctt gatcgttgtc
      661 ttcaccagaa cggctttcgt ctgaatccgt actattcgat tgatcatctg tattgtcgtc
      721 tgtttcatca gttccagaat ctgcgcctaa ttcgtcttta attccgttca attcatcaat
      781 aacactgtca atttcttctt tcacggcttc taaatctgct tcgcgtaatt ctcctgattc
      841 aactttttca cgtaattcag tcaatcgttg ctcacgacgt gccttcattt ttttcaataa
      901 ttctttatcc atgtattttt cctcctacgc ttctagcgct tgattaattt ttttgattaa
      961 tttttttctt tcttcgacgt ttttttctaa ttcatcacga cttcttaatg cagcttctgt
     1021 atcttcgtat gctggcaaag gcacaataga aacctcgtat aattccactt catggattgt
     1081 tcgaagcatt ggttcagaat tgtagtccca cgtttcttca gtcggcacaa aaccaaaact
     1141 acattggttg atgtctcctc gttccataga tttaactaag tcccttgcta ccgttgtgtc
     1201 cggtaaatca acttcgaatt tcaaaccacg ttcatcttct tcaaggcgaa gggttccgct
     1261 tttagtacgt cctagcacat tggaccaatc gtgattgaac aaacaacgaa catccgaatt
     1321 actaattgcc tttgagaatg caccaggaac aatcacttcg cttaagtcat cccataaaag
     1381 tgtttgactg ttgaatacag cagcgtagcc gctaatggtc ctcgtatgag tttcttcatc
     1441 ggaacgtgtt gaaagattgg tgatgtcaat cgtgcgaatt tccttcttct tcatttccat
     1501 cacctccttt caagtcttga tcattcgttg gtaaggaatc atctgttgca tttttctggc
     1561 caatcctaga taagtcattt gaaatataga tagcttgtgt ttctggagta ttctgtttag
     1621 gaaaaccaag catttctgcc acgttatctg gacttgtaat cccggtacga acgatgttgt
     1681 agccaatatt tgtttttgtt gagtaaggaa caaaatccaa aatattaatt ttccattcca
     1741 ctctatagcc agaattaggc ataaaaaaaa gagcggtgta atgttcgctc ttgtttttca
     1801 atattggttt gattgctttg ttgtgcagat acatcatcgc tttttcaata tctgtcttca
     1861 tcagcgattg atacgtatca acattgattc ctagaaattt tcctaagtct tttttgtaaa
     1921 cacctaaata attcaaaatt gccgcgtcat caacaggact ttttaatgtc tcgatggaat
     1981 atccttttcc caaaggaatc atcttaacag aatgatcact ctcattttgc gttccttcca
     2041 gttgatccaa tatagctttg acaatttttg tttgggcgct attatttgga ttgatgtggg
     2101 cgtctagttt aagcatgaac gcaagtaaac cgcctttagt atatttgtcc gtcaaaactt
     2161 tttcagcgct cagaacgcct tctagagtgt ttcttgcaag atcaattatt ccagcacctt
     2221 ttaatgaatc agttccgatg ttcttaatgt gtcgaatcat ttgaccaggt attttttgac
     2281 cattcatttc aaattcttct tgaagtcgtt cattgatttt agttgttaca ccgtacgcca
     2341 aatgaagctg atccctatcc gttaatggga atgtctcacc attgatcaat aaagtatttg
     2401 tttccaattt ggtaaattcg aatcctgtca aataatcatt gggactcttc aaaatattta
     2461 gtaagtgatg atctttgact tcgttgccgt cgggaccaat aacaattggt gtggccaatg
     2521 ccacctgatt agatatgtct tgaactaatt cataaacatc agaagattcc atgatagatg
     2581 aatccgtcac atatctttga ccataacgtg tgtagtgtcc aaaaatatcc tcgatatatc
     2641 cacgtttttc cataaaagaa tagactgcat tcgataaccg atcacgtaat ttcaattttt
     2701 ttcaccgcct ttctatttat ctatagatgg aacttaggta atcatctaac tcatctgaat
     2761 caatatctgt catttgattc atcgtttcct tatgaccaca caaaaacgcc acgaacccat
     2821 caatcttttt ctttgattga cgtttacttg gcgctttttg tccattgatg ttagtaattg
     2881 ctacaacgtt caaagtgcaa taaaggaata atggattatc aaattgaatt cgtttctcat
     2941 aaaacaaccg ttcgacatcg tcaaaaggag cattcaatac tttaggatat tgagcaactt
     3001 caacgcattc caatcctaag ttttctaatt tctcaacaag tttgtcactc atcgctggat
     3061 cataattcac ttgctgaata tcatataaat tcatgcagtc ctctatgtac tgcaaaatct
     3121 gatcttgatc aatcattttt ccgtcgcaaa attcaacgaa accttgttca gccaaatcac
     3181 tgtaaggaac attatcttct ttttctcgaa actctaaatc ttcattcgga ataaaataaa
     3241 gttgctttac tttaagaacc gctttaccat cttcatccca tgttgggaag tttaaagata
     3301 cacaggtcaa atctcgtgta cgtgataaat ctaaaccgat ataacatggt tcgccactta
     3361 aatcaccaag ttcttgtgtg gtaactaaac atggctctac ttgatcctgt tcaaagaaat
     3421 tatccgcgcc gttcacaaat acatccaagt gtttcgttag aaattcagct ttggaatgag
     3481 ctgaccgttg cgctgtttta aatgacgatt ctaaagcaga taaatcgact gatattcccc
     3541 agttaggatt gcacatttcc cagacttttc tatccgtcca atcataattt ttatttggct
     3601 catagattag aacaaagttt gaatcattat catcacgttt caacacttct tttgcttcgc
     3661 gatatacacg cattccaaca gacgacgaac ctttcccagc agttgagata ttaaacatca
     3721 atggctgtgg taaagatatc tgagcagact taaaattgtc atactgttcc attttctcct
     3781 gtttatgcaa ttcatcgttc aatacaaaat atggattgga tccctcgata ttatcaatat
     3841 tcttggtttg aacaataaat ttatttgagt aagccatatc ttcatgaata tagtcataag
     3901 taatactaga aacagttccc tttggccccc taaatatttt agttccttca agtaggattg
     3961 gattgtttaa gattgtaact gcaaaaggtt tggcagcata ttgcgcttga gcaaaatcag
     4021 atgcgcaagc atagcaatca actgataacg ccccttctcc gtacattgca tatcctaatg
     4081 aaccgacagc aatcaatgtt ttaccattct tttttggaat ctggacataa gcctcacgag
     4141 taacgcgtac aatttggcct ttttcatttt ctttaaccca accataaatc caagaataaa
     4201 taaatttttc ccagggttct aaaagaaacg gttttcccac catttctcct tttgtgtgaa
     4261 caataaatga ttctacccaa tccatcattt cattcgcgcg atctacatca aaccaaatat
     4321 cttttctttt tttccactga taccagcgat ctattgctaa acgaacggtc ttaggatact
     4381 tcttaggttt ctttcttact tcttttgcaa ataaatcagc ataatttaca ccaggttcaa
     4441 tcatttttca gcacctgcct tcttacgcca tttatttctg tgcgctgcta gttcatctac
     4501 tggctttact tctgggcgtg taatttcttc atcttttctt gcggtcgatc ctccagcaat
     4561 tagtctacca gtttttgctt tgtttgttaa tcctaataaa tctagagctt tcatcttctt
     4621 atctgcccaa gtttctactt gttgtgccaa tggatgtttt gattgattag tagctcctga
     4681 tttattcgtg aatttttgcg tctccggaaa tcctttttcc ttccacaata aatatttgtg
     4741 ttggtaaatt tcaaaaatat ccaagtatga ttcgattaat ggatcaagag tgatggtgta
     4801 caaatcagac aaattcatta tttctaagat acgagctttt tcagcactta ctttttcatc
     4861 aataatcgct ttacgttgcg ctttagtcgt catttttgta tacacccccc tttgtttttt
     4921 gaaaaatttg acctaacgat gcgcgtgact ccccgctacc ctatctcccc acgcgaaaaa
     4981 attttgaaaa tgaatagggg ggcttcaatt gaaatacgaa ggaaaaactt ttttgtcttc
     5041 cgtttcgttt tcaacaattg gatgacattt tgaacataat agcatgagat tgtttggatc
     5101 aagcttaagc agttcgttgt ctttgattgg tacaatgtga tggacgtgtg ctctctttcc
     5161 aaatatgaac tgaccacacc gctgacaatg accaccttct ctttcataaa taaattgacg
     5221 catatctttc catgcttgcg ttcgatagaa tggtttgttc tcatgatgat aaacagactt
     5281 tgcttgctgc ttcttcttgc gtgatctgct tgatctcttg tgttcagtac agtagatacc
     5341 ctttgctatt ttgttcgtgc atccgtcaaa ctgacagtat ttcattctac ttcacgaata
     5401 agatttatga tatcgccttt tgcacggata gcaccaggaa tatcaatacc atgtttctta
     5461 gcatatgcac gcaattcttt tgcagtcata ttgtccagtt catccgtatc ttcagtggac
     5521 tgatcattag tagcttcgtc tccatcaaaa ttagcagcag tgtttccatc gctatcaaga
     5581 atttcactgc tatgagctat gagttcgcca ttgacagcaa caaatgattt gccatcactc
     5641 aaaattcctt tttcttcttt tacttcaaaa tttggttctt gatctttcgg aacaactact
     5701 gtccttttct tttctgaatc ccaatactct gttccactaa tggatgttct aattttgatc
     5761 attgccattt taattctctc ctttgtaatt tgtacggatt acttttgcgc ccattcgctc
     5821 ataccattca atcgtttcct gcagattggg tagagtgtgt gacaataaag aaataactaa
     5881 cgtattcatt ccagttctgt aatcatcatt ctccacttgc acatgtgcat gattaccatt
     5941 ccaattttct ctgtacggac tattctctgc ttcaattgct ttcttataaa ctttagccaa
     6001 acttgattct acttcaatac taagtaccgc ttcatgaaaa tcattcattt gtttactctc
     6061 ctatcagata ttttgtggta tgatttataa aaaagatgcg aggtgtttta atgcttcaag
     6121 aagttaatat taagtatcgt gatcgtcaaa atacagagac aatttatttg ccaaatagtt
     6181 gtccgcattg cggaaatata atgactccgt atgtgtattt tggggtttca tcatatagtg
     6241 cgttcgataa tgatagaatc tttggcgtat tagtacagtg tataaatgat gagtgcaaca
     6301 aattttatag tttacaattt ataaatacgt ttaatgaaga tgaaggatat tctgaaaata
     6361 ttttaattaa agattattac cgtccgccga ttaaaataga tttaccagaa aatattgaaa
     6421 aagtttctcc tacatttgtt gatatttata ctcaagccac acaagctaaa tctgagcaat
     6481 tggaacaaat tgctggagtt ggttatagaa aagctctaga atttctaatt aaagattatg
     6541 caatatctaa aaattcagag gatgaagata aaataaaaaa aatgttatta ggtaaaacaa
     6601 ttgaaaatta tttgaatgat tttcctaaac tccaaagatt agccaaagct gctacttgga
     6661 ttggtaatga tgaaacgcac tatgttcgta gacatactaa taaagatgtt catgatatgg
     6721 atgcatttat taaatcagca gcgcaattta tcgcggctga ttatgatgct gatttagctg
     6781 atcaatttat aaatggaaat aactttatgc caactactaa ttaaaagaat aaaagagcca
     6841 cagataccaa ttaataaaac ggttgggata tcttggctct ttcatatttt tttgacacta
     6901 atagaatatc atgctgctaa caatgtttac atagctacaa tgaccgaaca tttagtgaac
     6961 agtgtaattt tagaataaag agagttgttc tttgtacttc tcgctattgt aaaaatcaat
     7021 ttcgttttct tttttcaatc ggtcagcttg tctgtgttca tactcatcta aaaagttcaa
     7081 tgtctttcta atttctgcat gtcgctgtct gacatacgat gagctatacc caacagattc
     7141 agcaatatct tctaagctca tttgatcaac atatttcatc ttaacaattt gattatcgat
     7201 accagaaaag ctatctatca gcaataacat ttcttctttt tgctcgatca acaattccaa
     7261 ttcattttct atcttttgga tattctcttc taaagaagaa gttctcgaat tcttttcgat
     7321 gcggacgttt gctaaatcac cacagaccca tcgattcaat tcaagcttac ttttattaag
     7381 attccacttt aagtaaagaa tctgctcatc tagttcttgg taatctttta accaatgaaa
     7441 tctcacaaac gccacccctt atggtagaat agtattgcgc tgctatctcg aaaggggtag
     7501 cttttttatt ttttcttagc cgttccattc tggattgcct tttgttccaa acgtcgtttt
     7561 ttcttcttaa tctttgattt tgtttttccc atacaattct cctttccgaa aacacatttt
     7621 gttcgatttt taatactaaa taaaagttgg ccagaatttt tcgttcgtct ttactcatct
     7681 ttttttgaat aagattacta gcataaaaat agttagtacc acgaaaatga acaggtaaat
     7741 caattacgtt caccttcttc atgccagtta tcagccacta gaatctttgc gttagtgccg
     7801 ccaccgtttt cttttttgta tttttcaaat gctttataag cagctgtttt tgatttatag
     7861 atttttccgg aaccgactgg gaacatccat gtgccctctg tgatagctaa gatgtatact
     7921 ttcatttaat tcaccccttt aatccccaac actacatatc cggacttctg catgtaatca
     7981 gtaatataag tgatctctgc tttgtatgag tcaccagtgt aactaaatgt tggtctcgtt
     8041 agtccaggta attcatgttt aatgtatttt ttatattcac gtagtattaa ctgatcacca
     8101 actttgaagt cacgatcatt cttgcggatc tcgaattgtt tgcgtccgct cgtcactgct
     8161 tcaaaatatt ctggtagtat ttttagttcg tggatcattc tgtttcctcc ttcaaaattc
     8221 gctcatcatc aaaaagtgaa tctccacaaa atccttctcc caaatattta tcgttcatgt
     8281 ataagtcaac caaatatttg tgatctgctt ctcgatattc attaatatta acgatcttta
     8341 ttttgtaaac attatcttcg tcgctcacta tcttgaattg ttctctgact ttcaccaccg
     8401 ttcctcctct ttttgaaaaa attttagtgt ttttgtaaga ccccctaaat cagctttttt
     8461 atttgatata atacttgtat cgattaatca aatcgaaatt aaatttaaaa aggtgattta
     8521 tcatgaatat caacaattta gtaaaactcg ttgaacaacg ttttaaagaa tcaggattag
     8581 aacaattaaa aaaagataat tctccagaat tattttctaa ttttaccgaa gacgacattc
     8641 ctactcttaa acaattaaaa tattattctg attattggac gcaaactcgt gagaatgaat
     8701 taaatttaga aaaactcatt attaaaaaga aatagcaact ccagcccaca cggctggttt
     8761 tttagtttca acttccctcc ttacgggtca aaatcatcgg ttccggcata atctgatcat
     8821 cctttagcaa caaatcagga tattttttcc ttagcttctt attgttcgtg taagttttca
     8881 atagccattg gttggcttcg cttttgcttt ctccagaaaa ataaattttc cctgtttgga
     8941 tgcctgcaag ttgaatcatc attttcacct caaatcaaat ttttttctgc tagatggagc
     9001 aaaagcaatc cgacatcaag aatcttttga cccattattt cagctacttt gctcggctta
     9061 actccttgag aaaagagcaa gcgtgcttgc tctatctctt cgtgagtcca aataaatttg
     9121 gcttcctcaa ggataattac tggatcagtt gctctcattg ttcctctgga aaaatgatgt
     9181 cattcttatg cttggaccag gtatctgcat atggaacaaa gtattgtcta gctaattcga
     9241 tttgatcaat taaagcagtt tctgataatt catggtctgc agcaatttca ttcatactat
     9301 cgccttcatc taaacagata agaccgttga cgttatcgat ttttacattt gtgactgctt
     9361 gactttctcc acgctcataa tattctacag ttgatactga tacatcagct tcggagttta
     9421 attgcagaat ctgttactgc cgggataatt taatattctt ttcataattc accttttttc
     9481 ctactgacat cgaatatttt tcatgttatg attagccgtg aaaggagagc tatattatgt
     9541 gtttacacat gatgtcctta gctcattcgg ttctttggaa gcttttttgg aaataactct
     9601 caggttcttg acgcaaatct catttattct ttgaaacaaa aaacttccat tttccgagag
     9661 ctttggatca cttcaaaaga gatttgcatt tatatttctg tgaccttgag tcgcgtaaag
     9721 aaccttacag caatggcggc aattccactt tcaggaaacc gccttttttc attgatattg
     9781 gtggttagcg gactacccat tttctttcgg cagtgccaaa ccacaaatga tctgtgttga
     9841 tgtttaggta gttgtatacc agataagcta aatccaaagt gcctgcatct tcaagacgac
     9901 aatattccaa aaattctccc atagctggac ataaaaatcc tggagctatc atatcccaac
     9961 agttaatagt gcaaagaaat tcgtttagct tctgaacgtt ttctttggtt tcacgaatta
    10021 caacatactc caattcttct ccgctggcag agcattccaa aacttcaaat tgattaagaa
    10081 atggtagaac atatgcttca aacatcaaca ttccatcttt ctgtttttgc acttgttttg
    10141 catcaatcat gtctatcctc ctattcagtt atttcttcca ttaatggaat tatttcaggt
    10201 cactggactt aacgaaaaca ccattgacca tctttccagt ccgacctttg atttcgtcat
    10261 aagcaaaatc caagcactcg tataaatcca tatcattttg cattgccaag atgatcaagg
    10321 ttactactac atcgccaatt ccgtctctta aaccatgttc atcttttcta gctagagaag
    10381 cggcaacttc cccgatttct tcgaccgttt ttaacatttg cttgctgaaa tccgcttgat
    10441 ccaatccctt atcttttgcc cactgctcta ctttcgcgat tagttcgtcc attatttctc
    10501 ctccacatac ctaaactgtc ttccttttga atcaatccat aagctcctag ctctatccca
    10561 aataatattt ttgctcagac cagtaatttc agataactgt ttagcggtac ccgttactag
    10621 aattcgatca ccatgccaga ttgcaatctt tctcggcgtt ctccgtttgg gcttttcagt
    10681 ccacattgat ttaccgagct tttggacttc tgcaactatt tttttatctt cctgccaatc
    10741 ttctgaataa gtcaattcga taattcgctg cattgccgct ttcttatcca tcccgacatt
    10801 ctcctttcag taatttgagt acttgatcaa gtgcgctctc acgtccgcca tgaaatgtgt
    10861 tgagccactt gtcttcgtac gacacacttt gtcttaaagc ttcttgatgc attaattcga
    10921 tctgtgctgt aaatgtcttt aggtccatct tgtttacacc tgctcaagtt cattaagatg
    10981 tttttgcaag cctttaacac aatcaatgaa tagtaatttg gtatatgcta aatttcttaa
    11041 ttgcgttcca tcgatataga gtgcgaaata gtatctgagt ttactccaac tcgaacgatc
    11101 attcttaatt ccttcaattc cagcttcttc gagttgatca tatacgtctc tcaggacgtc
    11161 taattcctcg ccctttttat aattcgctat ttcattaatt agttctagat aatcgatctt
    11221 catttttcca cctcttagaa tggtgctttt gattgtctat tagctcgttc tagcgctttt
    11281 ttcttgagat aggcttcttg gtcgattgcc cattcaggaa gcttctctcg tcttcctgtg
    11341 cgcttgtatc cactgcttgc gttcttaggt tcactttttt ctttccttgc ccaacttcga
    11401 atagttgcca aatagttttt ataagtctta ccagatgatt cacaatactc tgacagtcgt
    11461 tcgattcgct cttggtaatc attagggaat tctgttttga gtttctccat ctgctcatct
    11521 gacaaaagaa catttttata ctctccgtat ttatgacgga cgggcttagc cttcgatttt
    11581 ttcgaaggcg gtaactctct tatatattct tttgtattat taaatgtatt attaatagat
    11641 gtattattat ctttgacttt ttcgtcaata ggggtattgc gtttttcgtc aatagggtat
    11701 tgattaattc gtaggtacct attgattatt tgattggtac cctctttgta aatgatttcc
    11761 cgattcaagt atccaaactt aatcaaatca cttacccatc gcgatatggt ctctttattc
    11821 acaccatata aatctgcaaa gtactcattg cctgcccaac aaaagcctct ttcattacac
    11881 aaggccgtta tctctccgta taacaactta gtatttggtt taagtctttt gtcgtacctt
    11941 acgttggctg gtataatcgc ataataactt cgatgttctg tcatttttac cctccaatat
    12001 ttaacttttt gattgttttc tggtttaatt tgatcccttt gatttgatat ttatttttga
    12061 aattaatcac acctattttg tgcttctctg tgtgatggat tctgcagagt gctgcaaatg
    12121 tgtactctgc atgatcaact tctttgcgct ttcgtcttcc tag
//
LOCUS       DAFEIE010000075        11960 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFEIE010000075
VERSION     DAFEIE010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.078"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            296..1312
                     /locus_tag="LP345_002376"
     CDS             296..1312
                     /locus_tag="LP345_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL1761137.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            1453..2754
                     /locus_tag="LP345_002377"
     CDS             1453..2754
                     /locus_tag="LP345_002377"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBL1761138.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            2800..3462
                     /gene="deoC"
                     /locus_tag="LP345_002378"
     CDS             2800..3462
                     /gene="deoC"
                     /locus_tag="LP345_002378"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBL1761139.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            3483..3881
                     /locus_tag="LP345_002379"
     CDS             3483..3881
                     /locus_tag="LP345_002379"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBL1761140.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            3947..5029
                     /locus_tag="LP345_002380"
     CDS             3947..5029
                     /locus_tag="LP345_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1761141.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            5241..6803
                     /locus_tag="LP345_002381"
     CDS             5241..6803
                     /locus_tag="LP345_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1761142.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            6796..7929
                     /locus_tag="LP345_002382"
     CDS             6796..7929
                     /locus_tag="LP345_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1761143.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            7929..8885
                     /locus_tag="LP345_002383"
     CDS             7929..8885
                     /locus_tag="LP345_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1761144.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            8984..10150
                     /gene="deoB"
                     /locus_tag="LP345_002384"
     CDS             8984..10150
                     /gene="deoB"
                     /locus_tag="LP345_002384"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBL1761145.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            10174..10992
                     /locus_tag="LP345_002385"
     CDS             10174..10992
                     /locus_tag="LP345_002385"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL1761146.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            11009..11716
                     /gene="deoD"
                     /locus_tag="LP345_002386"
     CDS             11009..11716
                     /gene="deoD"
                     /locus_tag="LP345_002386"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL1761147.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKKFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         3781 a         2128 c         2786 g         3265 t
ORIGIN      
        1 tagtggagcg acgaaagagt ggaactgggc gtgcatgtac gggtacgtat cagttctttt
       61 tttgttgaga agtttttaaa aacaaagaac tattttttct tcaaaaagaa atagtaggaa
      121 cagagtcgtt gttttttacg ataaaataaa taagatacag aacttgtata gaaggctgcc
      181 aagtcggtag ataaaggagg tttttatcaa aaaacatact ttcctttttt ctctattctt
      241 ttcttggggg ttttggtaca ctgataggga atttagatag aagggagcca ataggatgaa
      301 gctgaccatc agagatatcg cagaaatggc aggcgtatca gtaacaactg tctcacagat
      361 tttgaataac aaaggaagca gatttagtga taagacaaga aaaaaagtgt tgtcgatcgt
      421 gaatgaacat cattataagc ccgattattt cgcttcaaat gtgatcaatc gacattcaaa
      481 gaccatcgga atgatcgtcc ctgatgtcac tgatttcttc ttctccaaac tgatcgaagg
      541 tgtagagagc tatttgaatc ctttgggcta tgtgatcatg ttatgcaatt ctcgtcatag
      601 ccaagaaaat gagatcaagt atttacaaga gctttcccac cgctcagtgg acggaatctt
      661 gctggccaca ccaaatattt tacctgagaa atatgcatta gacagcggtt tttatcaaaa
      721 aatgccaatc attttaatcg atcgcggatt gaatcgtcgg gataacggac ggcttatcgt
      781 aaaggaatat gagggcgcct atcaagctgt ttcgctgttt attgaaaatg gccatacgaa
      841 gatcggcatg ctgaaggaaa ccactggata ctatcaatta gaagaacgtt tcaacggata
      901 tcgtcatgcg ctgaaagatc atggcctgcc ttttaatggg aaatttgttg aacatggaga
      961 gttgactgtc caaggtggat atactgcatc aaaaaaatta ctcaaacata aagatatcac
     1021 ggctattttt tgcgggaatg atgccatggc gatcggatgc tatcaggcga tcgatgaatt
     1081 gggcaaaaaa atcccagaag atatctcagt cataggattc gatggattaa agctgtcaga
     1141 atacatgatt ccgcaattga cgacagtgca gcagccaagt tttgatattg gattttatgc
     1201 tgcacgtttc ctgatcgata cgatcgaatt tcctcaaaga aaagttccga acaaagtgtt
     1261 cgaaacaaaa ttaattattc gtgagagcgt aaaagtattg acaaagggct aactcggcgg
     1321 tatattgctt atgtaagcat ttacaaaggc tagttagtgc tttttttatt tttagtaaac
     1381 cagtttacta aagtggttta cctttcctaa aaataatgta taataccgaa tgaagacaag
     1441 gaggatcagg caatgcgaat ggtggatctg attgaaaaaa agagggatgg aaacgagctg
     1501 tcgaaagagg aaatcgagta catcgtcacg aactatacga atggaaagat tccagattat
     1561 caagtcagtg cattattgat ggcaattttt tatcaagaca tgacaaatga agaaatcacg
     1621 aacttaacat tggcgattgc taattctggt gatgtcatcg atttgagttc tcttgaagga
     1681 ataaaggtag ataagcattc gacaggtggc gttggtgaca cgaccacatt gattttagcc
     1741 cccctagtag ctagtgtcgg agtgacagtg gctaaaatgt ctggacgcgg tctaggttac
     1801 acaggtggta cactagacaa gctagaagca attcccggat ttcagatcga gctttcggat
     1861 gaagaatttg tacgcattgt taatgaaagt aaagtagcgg taattggtca atcaggaaac
     1921 ttggcaccgg cggacaaaaa attgtatgcc ttgcgtgacg tcacagcgac cgttgattct
     1981 cttccgctga ttgccagttc gattatgagt aaaaaaatcg cggcaggagc agatgcaatc
     2041 gttttggatg tgaccactgg agacggtgct ttcatgaaga acatcgaaga tgcaagacgt
     2101 ctggcaaaga ccatgacgag cattgggaaa ctggctaacc gagaaacagt ggcggttatc
     2161 tcagatatgt cagaacctct tggcgaagct atcggaaata gtctagaagt tgtcgaggca
     2221 atcgaaacat tacaaggaaa tggtccagaa gatctagtag aaatgtgcta cgccttagga
     2281 agccaaatgg ttgttcttgc tggcaaagct aagacaaccg atgaagcaag aacgttgctt
     2341 caagaagctc tggaatcagg taaagcgtta gcaaaattca aagaaatgat ccaaaatcaa
     2401 gggggagacc cagcgatcgt ggaacatcca gaacgaattt tgactgcacg ctacacaatg
     2461 gagcttcctg ctaaacaaag cggagttgtg tcaaaaatcg tggcaaatga attaggaatt
     2521 gctgcaatga tgctaggtgc tgggcgtaaa accaaagaag aagatattga tcacgctgtt
     2581 ggattgaaac tgcataaaaa aattggtgac actgtgacaa aaggtgagtc actattgacg
     2641 atctatagta acgacgaaga aatcacttct gtcattgaat tattatataa aaatattgaa
     2701 attggtgaat cggcaatgaa gccaacgttg attcatgaca tcatcacaga ataaaggaaa
     2761 aaagcggact ttaccgtttt aaagaaaagg ggaaaagaaa tggaactaaa ccgaatgatc
     2821 gaccatacta ttttgaaagc agacgcatct aaagaagctg tgatgcaaat tatcgaagaa
     2881 gcaaaaaaat accattttta ttctgtctgc atcaatccag catgggttgc gctagcgaaa
     2941 gaacaattac aaggtgagcc agtagccgta tgtacagtaa tcgggtttcc tctaggagca
     3001 aacacacccg agacaaaagc atttgaaaca acagatgcca tcaataacgg tgcagatgaa
     3061 gtcgatatgg tcatcaatat cggtgctttg aaatcaaagg atgatcaaca agtccaaaaa
     3121 gatatcgaag cagttgttga agcagcaaaa gatcgtgcgc ttgtcaaagt tattattgaa
     3181 acatcgttat tagatagaga agaaatcatc cgagcttgcg aaatagcaaa agctgcaggc
     3241 gctgattttg tcaaaacatc aactggtttc tcaacaggcg gagcaaaggt agaggatgtc
     3301 cgtttgatgc gtgaaactgt aggaccagaa atgggtgtca aagcttccgg cggtatccat
     3361 aacgaagaag aagcaatggc aatgatcgaa gctggtgcta caagaatcgg aacaagcgca
     3421 ggagtagcaa tcgtatctgg ttcaactggt gaaggctatt aattttttca aaggagaagc
     3481 tcatggcaga actcaaacaa gaatggatca acacagctat tgaagcgtta gataaagcct
     3541 atgttcctta ttcccatttt ccggtaggcg cttgtctcgt aacggaatca ggcaagattt
     3601 atcaaggcat caacattgag aatgcatcat ttggattaac gaattgtgcc gagcgcacag
     3661 cttttttcaa agcagtatct gaaggagaaa aaacatttac gcatctagtc gtagcggggc
     3721 acacccccga tcctatctct ccttgtggtg catgtcgaca agtaatggca gaattctgtt
     3781 cccctgatat gccggttacg ctagtaggag acaatggtgt gacgaaggca acgaccgttc
     3841 gtgcactgct gccttatgca tttactgaaa aagatctata actcatgttc attcagtcag
     3901 ctgactgttg aaaaataaaa caattatttt aggaggcttt acagaaatga aaaaagcaaa
     3961 attatttggt ttaggtgctg tcgcactagc agcagggtta tttttaggtg catgcggcaa
     4021 caacggctct actgattcat ccggtggcaa aagctcatca gacacaacaa ctgcagcatt
     4081 gatcacagac acaggtggtg tagacgaccg ttcattcaac cagtcagctt gggaaggact
     4141 agaaaaatgg gggaaagatc aaggactttc acgaggaaat gatggcttcc aatatttcca
     4201 atcttcaaat gaatcagatt acatcccaaa tattgaccaa gcattgaatg ctggattcaa
     4261 aacgattttt ggtattggtt ataaactaaa accagcgatc caagaacaag caacaaacaa
     4321 tacaggtacg aactttgtta ttatcgatga tgtcatcgat ggattagata acgttgtatc
     4381 tgcaactttc aaagacaacg aagcttctta tcttgcaggt gttgcagcag cttatacgac
     4441 tgaaacaaac gtagtcggct ttatcggcgg tgtaaaaggt gaagtaatcg atcgttttga
     4501 tgctggattc aaagccggtg ttgatgcagg tgcgaaagaa ttaggaaaag aaatcaaagt
     4561 attgaatcaa tatgctggtg acttctctgc tccagataaa ggacgttcaa ttgctcaagg
     4621 tatgtatgca caaaacgcag atatcatctt ccatgcttca ggcggtacag gtaacggtgt
     4681 attccaagaa gcaaaatcat tgaacgaatc aggcgacaaa aaagtttggg ttatcggtgt
     4741 tgaccgcgac caatcagacg aaggcgaata cacattaaac ggcgaaaaga aaaacttcac
     4801 attgacatct acactgaaag cagttggaac agtagtagaa gatttggcac aaaaatcagc
     4861 ggacggtaaa ttccctggcg gcgaacacac tgtttatgga ttgaaagaag acggtgttgg
     4921 tctaacagaa ggacaacttt ctgacgaagc gaaaaaagca gttgatgaag caaaagaaaa
     4981 aatcatttca ggtgacgtaa aagttccaga aactcctgaa gaaaactaaa accatttcta
     5041 tagccttgtt agacacatgt ttgacaaggc tatggtttga ttagaacaag aattgttcat
     5101 ttatccaagc tgccttgtga cagtttggat aagggaacaa ctccctgaag taatgtttgt
     5161 ttcaaaagaa gaacgctcac taagcgtgaa tcttagtcaa tcgttgccct agatagaaat
     5221 cgttaggatg tgaaaaaaag gtggttcaag aaaatattgt catagaaatg cagaatatta
     5281 ccaaagaatt tggaacattc aaggcaaatg acaacatcaa tttacaagta aaggcaggag
     5341 aaattcatgc gttgcttgga gaaaacggtg ctggcaaatc tacattgatg aacgtgcttt
     5401 ccggattatt agagccgaca tcagggaaaa ttttgatgcg tgggaaagaa gtaaagatca
     5461 caagtccgac caaagccaac caattaggga ttgggatggt ccatcagcac tttatgcttg
     5521 ttgatgcctt tactgtaaca gaaaacatcg tgttgggaag cgagcctagt cgcgcaggga
     5581 tgcttgacca taaaaaagca cgaaaagaga tccaaaaagt ttctgaacag tatggattgt
     5641 cagtcaaccc agatgcttac gttcgtgata tttcagttgg aatggaacaa cgggtagaaa
     5701 ttttaaaaac actttaccga ggagcagatg tactgatttt tgatgagccg acagctgtat
     5761 tgacccctca agaaattgat gaattaatcg tgatcatgaa ggaattagtc aaagaaggca
     5821 agtcgatcat tttgattacg cataagttag atgaaatcaa agcagtagct gaccgctgta
     5881 cagttatccg ccgtggaaaa ggaatcggta cagtcaacgt taaagacgta acctcacaac
     5941 aattagccga tatgatggtt ggaagaacgg tttcattcaa aacgatgaaa aaagaagcga
     6001 agcctcaaga agtcgttttg tctattgaaa atctagtggt gaaagaaaat cgtggattag
     6061 aagccgtgaa aaacttgaac ttagaggttc gtgctggcga agtacttggt atcgctggaa
     6121 tcgatggaaa cgggcagtcg gagttgatcc aagctttgac tggtttgcga aaggcagaaa
     6181 gcggacatat caagctaaaa ggggaagaca tcactaataa aaaaccccga aaaatcactg
     6241 aacatggtgt aggacacgtg ccagaagacc gtcataaata cgggttagtc ctagatatga
     6301 cattatctga aaatatcgca ctacaaacct atcatcaaaa accttacagt aaaaacggca
     6361 tgctgaatta ttcagtaatg aatgaacatg ccagagaatt gatcgaagaa tatgatgttc
     6421 gaacaacgaa tgaacttgtt cccgcaaaag ctttatcagg cggaaatcag caaaaagcaa
     6481 ttatcgctcg tgaagtcgac cgagatcctg atctgttgat tgttgcaaat ccaactcgtg
     6541 gactggatgt aggtgcgatc gaatttattc ataaacgtct gatcgaacaa agggacaaat
     6601 acaaagcagt gttactgatc agtttcgaat tagaagaaat tttaaatgtt tcggatcgta
     6661 ttgctgttat ccatgaagga gaaattgtcg gtatcgttga tccgaaagaa acatctgaaa
     6721 atgaattagg tctattgatg gcgggctata ccttagaaga agcacgaaaa gagttagaaa
     6781 agggggctgg cgcacatgaa tgatcgcagc gaaaaattcc gtaatttatt agtgcctgta
     6841 ctttcagttg ttttaggatt gatcttaggc gcgatattga tggctgcttt tggttttcag
     6901 cccatccaag gttattcttc tatgctagat gcagcccttg gttcgcaaag agggataggt
     6961 gaaacgttaa ggcaagcaac gccgttgatt tttacagcat taggtttttc tgtagctaac
     7021 tcagctgggt ttttcaatat tgggctttct ggacaagcac tttgcgggtg gatcgtcagt
     7081 gtctgggtgg cacttgcgtt tccagatctg ccaaaagttg ttttgcttcc gttatgcgtg
     7141 atcttaggtg ccttagctgg tgcgatggca gcggctgttc caggtttact tcgagcattt
     7201 tttggaacaa gtgaagtgat cgtaacaatc atgatgaact atatcttatt atacgtaagc
     7261 acatttgctt tacatgaagt gatgcctgaa agctatcgct caagtttgga ctcttccaat
     7321 atgatcagtc aaaatgcctc actgcggtta ccatggttaa cacaagcttt tggcggctct
     7381 cgcgtaaact caggattatt tttagcaatc atcgcgctta ttttcgtttg gctgctgatg
     7441 aagaaaacga ctttaggatt tgaaatccgt tctgttggat tgaatccttt tgcttctgag
     7501 tatgcaggaa tgagtagtaa acgtacgatc gttttgtcga tggtcatttc tggcgctttg
     7561 gcagggcttg gcggtgtggt tgaaggatta ggaacgtatc aaaacttctt tgttcaaacg
     7621 acttcgctat ctattggatt tgacggaatg gctgtttcct tgcttggttc tggatcagca
     7681 atcggtattc ttttatcagc gatcttgttc agtattttga agatcggtgg acttggcatg
     7741 cagacaggag caggtgttcc gtttgagatc gtcaatgtat cgattgcttt gattatcttc
     7801 tttgtcggga tcaacttcct gattcgtttc gtcatggcta aagtcttcca agggaaaaaa
     7861 caagaagaga tcgttgcgac aatagaatcg aaaccaacga atcaaaacca tgaagggggc
     7921 gaactataat gtcgactatc gaattaattg ccttgatcct tacttctaca ctggtttatt
     7981 caacaccgct aattctaacg tcactaggcg gaactttttc tgaacgaagc gggatcgtaa
     8041 acgtagggct agagggaatc atggtcatgg gtgcttttag ttccatcgtt ttcaacttga
     8101 cgatgagtcc atcacttggt tctatgacac catggatcgc tattttagtg ggtggcgtcg
     8161 taggtatcct attttctctg attcacgcag tagcaacagt cagtttgcgt gctgaccata
     8221 ttatcagcgg gacagtaatt aatctgatgg cacctgcttt aggtgttttc ttgatcaaag
     8281 catggtatgg taaaggtcaa actgataaca tcacgcagaa tctggggtat ttttctttcc
     8341 caggattagc agatattccg gtcattggac caattttctt taaaaataca ttcttacctg
     8401 cttattgtgc tattttgatt gctgtcctag cttgggtgat catcttcaag acgaaattcg
     8461 gcttgcgcct ccgttcagtt ggtgaaaatc ctcaagctgc cgacacatta ggtatcaatg
     8521 tatatgctat gcgttattca ggcgtactga tttctggctt gttaggcggt atgggcggtg
     8581 ctgtttttgc tcagtcgatt tccggtaact tttcagctgg tacgatcgtt ggacaagggt
     8641 tcatctccat ggctgctatg atctttggta agtggaatcc tttaggggca atgggtgcct
     8701 cattgttctt tggttttgct caaagcttga gtatcattgg cgcacaatta ccagttattt
     8761 cttcgattcc gccagtattg ctgcaaattg ctccatattt gctgacaatc attgtgctgg
     8821 ttgttttctt agggaaagct tctggtccaa aagcaaacgg gaagaactat atcaaatcaa
     8881 aataatcttt tagcgaataa aaagggtggg ttacgggaag tgtttttcgt ctcgcccttt
     8941 ttgttttaaa ggcaataaaa ataaaaagaa agaaggaata atcatgttta aacgcgtaca
     9001 tctgatcgtc atggattcag taggaattgg agaagcacca gatgccgata agttcggtga
     9061 tgttggttct gatacattag gacacattgc gaaagaagca ggattgaacg ttccacattt
     9121 agagcagctt ggtttaggaa cgatccgtcc tcttgaaggt gtggaatcag tgaaagatca
     9181 tcaaggctat gcgacgaaat tagaagaagt ttctgtaggg aaagatacga tgacaggcca
     9241 ctgggaaatc atgggattga atatcaaaac tccatttcgt gtgtttccta atggattccc
     9301 tgatgatctg atcaaacaaa tcgaagaatt ttctggccgt aaagtcgtat gtaacaaacc
     9361 ttatagcgga acagctgtta ttgacgatta cggtgaacac caaatgaaaa caggcgattt
     9421 aattgtatat acttctgccg atcctgtcct tcagatcgcg gcacatgaag aaatcattcc
     9481 tttagaagaa ttatatcgga tttgccaatt cgttcgtgat ataacaaaag atgatccgta
     9541 tatgattggc cgaatcattg cacgtccgta cgtgggtgaa ccaggagact tcacacgaac
     9601 aagcaatcgc catgattatg cgttgaatcc attcggacac acagtccttg attctttgaa
     9661 agaagcagga aaggacgtga ttgctgttgg aaagatcaac gatattttca acggacaagg
     9721 aatcactgaa tctgtccgca cgaaaagcaa tatggatggc gttgaccagc tgctgaaagt
     9781 tatgaaaaac gatttttcag gaatcagctt taccaattta gtagattttg atgcattata
     9841 cggtcatcgt cgggatgtag tcggctatgc gcatgcgatt gaagaatttg acttacgaat
     9901 tccagaattg cttgaagcga tggaagaaga cgacttgcta atgattacag ccgatcacgg
     9961 aaacgatccg acgtttactg gtaccgatca tacgcgagaa tatgtaccgt tattggttta
    10021 cagtaaaaaa atgaaagaac aaggggcatt gcctcaagga tattattcag atatttcagc
    10081 aacgattgct gagaacttta gtgtttcttc gactgaaaat ggcgaaagct tcttgaaatt
    10141 attaaaataa tctttttaaa taggagaaag caaatgacca agttaagcga gatgttacaa
    10201 gaaacgaccc agtttatcct tgataaagga gtaaaagaaa ttgattttgg tttgattcta
    10261 ggttcaggat taggtgaatt agcagatgaa atcgaagatg ctgtaatgat ttcttatgat
    10321 gagatcccgt tctttcctgt ttcgacagta gttgggcatg caggaaagct agtttatggg
    10381 tctctggcag gcaagaaagt gttagccatg caagggagat tccactacta tgaaggtcat
    10441 tccatgcaaa cagtgaccta tccagtacgt gtgatggccg gactaggggc ccattcagtc
    10501 attgtgacta atgcatgtgg tggtgtcaac gaatcatttg taccaggaga tttgatgctg
    10561 attaccgatc atatcaattt tactggtgaa aatcctttga tcggtccgaa tgaagatgca
    10621 atgggcccta gatttccaga tatgagtcaa gcttatacgc ctgactatca agcaacagca
    10681 aaagcagcag cagaaaaact aggtttggat cttaaagaag gcgtatatat gggctattct
    10741 ggaccaactt atgaaacgcc tgcggagatc cgaatgtctc ggacaatagg agccgatgca
    10801 gtagggatgt cgactgttcc agaagtcatc gtagcagctc acagcggatt aaaagtgtta
    10861 ggaatctctt gtattaccaa cttagcagca ggtatgcaag cgaatctgag ccatgaagaa
    10921 gttgtagaaa caactcagag agtcaaacaa tcttttaaag cattggttaa agaaacattg
    10981 acattattgt aataggagga acaataaaat gagtgtgcat attgaagcga aagaaggcga
    11041 gatcgccgat aagattttac ttccgggaga tcctttgcga gctaaatata ttgcggagac
    11101 ttttttggaa gatccagttt gttacaatca ggtacgcggt atgttaggct ttaccggcaa
    11161 atataaagga gaacgtattt ctgttcaagg aacaggaatg ggaatgccat cagccaccat
    11221 ctatgcccat gaattgatcc agtcgtatgg tgtaaagaaa ttgattcgag taggtacatg
    11281 cggtgcattg tcaaaagacg tccatgttcg tgatttagta ctagcacaag gtgcagcgac
    11341 cagttcttcg atgatcgaaa aaaaattcca agcctttcat tttcctccaa tcagtgattt
    11401 caatctatta ctgaaagcat atgagatagc taaagaaaag ggctatacgg ttcatgtagg
    11461 aaatgttctt tcggaagatt ctttctacaa agatgatttg acagagacgt tccaattagc
    11521 tgaacttggc gttttaggag tggaaatgga agcagcggct ctttattact taggcgcgaa
    11581 ataccatgtg cagacattaa gtttgatgac cgttagcgac catttgatca ccggtgaaga
    11641 aacaacagct gcagaacgtc aatctacgtt caatgaaatg atcgaagtag gattggaaac
    11701 agcgatagca gaataagaag gaaatgaaaa agctgccctg cattaagtaa taagaacatc
    11761 caagcaaaaa tagctcctca tgtttttgac ttggctggac ttattattgc aaatgtaagc
    11821 ttttgaacac cgtttaccaa gaggttgtga atctgccgtt taactctgag tcacaaggaa
    11881 caatttcaaa aaacagcttt tcatgtttga tgaatattgt gacttgtgac cgagaagttg
    11941 gcaggagaaa accgtttata
//
LOCUS       DAFEIE010000076        11725 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFEIE010000076
VERSION     DAFEIE010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.079"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(93..968)
                     /locus_tag="LP345_002387"
     CDS             complement(93..968)
                     /locus_tag="LP345_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL1761148.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(1050..1841)
                     /gene="codY"
                     /locus_tag="LP345_002388"
     CDS             complement(1050..1841)
                     /gene="codY"
                     /locus_tag="LP345_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBL1761149.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(1859..3259)
                     /gene="hslU"
                     /locus_tag="LP345_002389"
     CDS             complement(1859..3259)
                     /gene="hslU"
                     /locus_tag="LP345_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBL1761150.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(3273..3821)
                     /gene="hslV"
                     /locus_tag="LP345_002390"
     CDS             complement(3273..3821)
                     /gene="hslV"
                     /locus_tag="LP345_002390"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBL1761151.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(3858..4763)
                     /gene="xerC"
                     /locus_tag="LP345_002391"
     CDS             complement(3858..4763)
                     /gene="xerC"
                     /locus_tag="LP345_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBL1761152.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(4961..6337)
                     /gene="trmFO"
                     /locus_tag="LP345_002392"
     CDS             complement(4961..6337)
                     /gene="trmFO"
                     /locus_tag="LP345_002392"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBL1761153.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(6306..8384)
                     /gene="topA"
                     /locus_tag="LP345_002393"
     CDS             complement(6306..8384)
                     /gene="topA"
                     /locus_tag="LP345_002393"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBL1761154.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(8506..9363)
                     /gene="dprA"
                     /locus_tag="LP345_002394"
     CDS             complement(8506..9363)
                     /gene="dprA"
                     /locus_tag="LP345_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBL1761155.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(9419..10186)
                     /locus_tag="LP345_002395"
     CDS             complement(9419..10186)
                     /locus_tag="LP345_002395"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBL1761156.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(10179..11039)
                     /gene="ylqF"
                     /locus_tag="LP345_002396"
     CDS             complement(10179..11039)
                     /gene="ylqF"
                     /locus_tag="LP345_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBL1761157.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            11299..11697
                     /locus_tag="LP345_002397"
     CDS             11299..11697
                     /locus_tag="LP345_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1761158.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         3088 a         2552 c         2057 g         4028 t
ORIGIN      
        1 aatcgatgtc acactccctt attacttaca ggatagcttt tttacacacc ttggtaaacg
       61 gtgttccctg ctaacttctc ggtcacaacc tcttacttca ctgtgatgga atattttgtc
      121 ttgaagattt catgggcacc tagttgattg atccctactt tttccatcaa gtttccacta
      181 ctgttcaccg tgtcagcgat tccgcaccac ggttcgatac aaacgaaagg cgcttctttt
      241 ggataaggag accagatccc tacataaggc atatctttat agcttaaagt tacgctatgg
      301 gaagattttt cacttcgaat ggcgtacgca tttagacccc ttgtttcaaa aaccaaggca
      361 tcttgctcaa aaagttcacg attcaaagcc agattcgtat ttgtctgacc taacgtcttt
      421 tgatccatat cgatgaatgg gcctttcaat ggtaggcgta atcttgattt caatggagaa
      481 aatgccagat agaaatcttc aaatgacaat ccttcttcaa gaggtacatt gaaagcagga
      541 tgtccaccga tagaaaagaa catttctttt tcaccggtat ttgccacttg ataatgaacc
      601 gtgatgccgt ctcctcctaa ttcatagctg atcactaatt caaaatcaaa tggatacttt
      661 tctaatgtct ccggcgtact ccttaagatg aaactagcca tttcttgtcc atgttcaatg
      721 acttcaaaat ccatatcccg agcaaatccg tgttgcccca tttgatatgt tttcccttga
      781 taaacatact gatcatcttt taaacgtcca acaaaaggga ataaaaccgg tgcatgtctg
      841 ccccaatacg ctggatcacc ttgccagata tactctaaac catgttcttt tgatttcaga
      901 ctgatcaatt ccgcaccgtg ttcagcgatt tcggcgatca gctggtcatt ttgaataata
      961 acagtcattg ccattcctcc aacttcgact tactttttaa aatgggaagg ctggaacaaa
     1021 catttctatc tgccccagtc cccttacttc taataactgt gttttgctaa ctcgtcttta
     1081 aaacgggaat tcaatacttt taaataagtt cccttcatgc ctaacgaacg agattcaatg
     1141 attccagctg attccaattt tcgtaaagca ttgacgatca cagaacgagt gatgccgata
     1201 ctatcggcaa tattagaagc agtcagacga ccttcatctc catccaatgc ttcaaagata
     1261 gcttgtacag ccttcaattc gctataagat aatgtgttga ttgccatttg gacagccgtt
     1321 gcactccgta catctgcttc gatgcttcga gacttctgat aaaggatctg cataccgaca
     1381 accgtagctc catattctgc taagactaga tcgtcatctg caaacgattg ttccatacga
     1441 gataagataa tcgtacccaa acgttcgcca gctccaaaga tcggaacgac agtcgtcaga
     1501 ccaaatggat atttctctct tgactctacc ggaaatgcag taatatcact agtaattggg
     1561 atattagctt cagttttcat caactgtgcc actgtatcag tataagattc aggaaattgt
     1621 ttctcaacaa acattgtttt gattcgttca ttgttcacat cgtgacgttc attataacct
     1681 agtaatactc cgtcacttcc tatgatatag gtgttgctgt caagaatacc acctagtgtg
     1741 acagccattt tatcgtaagg caaatctgct tgcatgtcaa aagtattctt ttgctgcaaa
     1801 agtgtgttta tcttgcgggt tttcgttagc aagtctgtca ttgtcgtcct ccgatttttt
     1861 ataaaatata gcgacttaaa tcttcatttg ccgcaattga gccaagtttg tcatccacat
     1921 atgcttctgt gatcgttatt tctcccattt gcatatctgg tgcttcaaat aatagatctt
     1981 ctagtagttt ttccaaaatg gtatgcagtc tgcgtgcgcc gatattatct gtgtcacggt
     2041 tgacatcgaa agcgatttga gcgatccgtt caattgcttc ttttgtaaac gtaactgaca
     2101 cattttctgt accgatcaac gcgacgtatt gttttactaa agcattattt ggttcggtca
     2161 gaatcttcac aaaatcttca gctgtcaaat catctaattc tacccgtatc gggaagcgtc
     2221 cttgaagttc tggaattaga tcacttggtt tagacaaatg gaaagctcct gaagcaatga
     2281 ataggacgtg atctgtttgg atgatcccgt attttgtgtt tacttgtgaa ccttcgacaa
     2341 ttggcaatat gtctctttgg acgccttctc tggatacttc tccagattgc tgtgatttag
     2401 aagtgatctt atcgatttca tcgataaaaa taattccact ttcttccgct aatttgattg
     2461 cctcactatg gatatcagca tccttgacta attttgctga ttcttccttg atcaataact
     2521 ctaaagcttc tttgactgtt accgtccgtt ccactttttt cttcggtgtc aaagcaccta
     2581 gagtttcatt taggtcgatc cccatttgct ccaatccatt gttcatcatt ggtgcaggtt
     2641 tcttttggtc ttcaacttca atggttactt cacgactatc cagtaaaccc ttttgtagtt
     2701 gttccaagac tgtacggcga ttgattcgaa tatcttctgt cacttcttct tgcggttcag
     2761 cggtattttg ctgactagca ttaaaaagat tcatcatttg ttcaaattga ttagtggatt
     2821 gtttctgttc ttttttgata ccaggtacca agatttttac caaacgtttt tctgcatttt
     2881 ttttagcact tgtgtataca cggctgtact gctctttttc tacgatttgg atcgcatttt
     2941 ctactaaatc ccgaaccatt gattctacat ctcttccgac ataaccgact tcagtaaatt
     3001 ttgttgcttc gactttgaca aatggtgcat tgacgatttt tgccaaacgt cgtgcgattt
     3061 ctgttttacc gacccctgta ggtccgatca tcagcatatt ttttggtgta atatcttgtt
     3121 gcattttttc atctaactgc aaacggcgat agcggttacg caaagcaacg gcaacagatt
     3181 tttttgctgc gtgctgtcct acgatatatt catctaattc acttacgatt tgtcttggtg
     3241 tttgttttaa ttcatacata tctactcacc tcttacagtt cttctacgat aatattatga
     3301 ttagtaaaga tacagatatc tgcggcaata tttaacgcat tttctgcaat ttctttcgca
     3361 ctcatgtcgt tttgagcata gtttttcatt gctcgggctg cagccaacgc aaaattccct
     3421 cctgatccga tagctaagat accatcatct ggtgtgataa cttctcctgt acctgaaaca
     3481 agaagcattt ctttatcatt cattacgatc agcatcgctt caagtttttg catagattgc
     3541 tgtgtccgcc attcttgagc taattcgaca gctgcgcgtt gtagattccc gttatattcg
     3601 tttagtttgc cttcaaattt ttcttctaaa gtaaacgcat ctgcaacact tccggcgaaa
     3661 cctacaacaa cttctccatt gtagatacgt cgtactttct ttgcagtgcc tttcatgaca
     3721 acagattcac ccattgttac ttggccatct ccagccatag caaatttccc gtctttttcg
     3781 acggcacaga tagtggttga atgaaatggt gattcgacca tgtttgtttc ctcctaaatt
     3841 tgttcttttc cttattttta cgctcttgga tggaaagaac gatagttttt ttgtaaactt
     3901 tcttttgtta catgggcata gatctgggta gtcgataaat tggcatgtcc tagcaattct
     3961 tggactgtcc gcaaatctgc cccattattt aataaatgag tagcaaatgt atggcgcagc
     4021 atgtgaggat ggatatcact atccaaactg ctttttttga tcatttgatt caagacatat
     4081 tcaattccag taggcgtgat tggttttcca tgatgattca caaaaacgat atcatgctct
     4141 tcgtgatatt ttgtcatcaa tacctggcgg ccttccctga aatattcttg cagagcatct
     4201 tgagcaaaag aacctagagg agcatatctc tctttgttcc ctttaccatg gatcaacatg
     4261 acctctgaat caaaatcaat gtctgatacc gacaaactgc tacactcact taaacggatg
     4321 cctgacccgt aaaggacttc cagtaaagcg cggttcctca aatccaaagg actatctcct
     4381 gctacgctgt caaaaagtgc ttgcatttca ttttcataaa aaaaacgtgg cagtctcaaa
     4441 tttttctttt tgagatgaac gtaagaaaat ggattttctt ttatcacttc ttctttgaga
     4501 agatactgat aaaacgaacg taggctggct atcttgcgac tgatagaatt tctgctatag
     4561 ctaggacgat gatcagctaa tgcactcaaa tagacacgaa ccgtaaaata ttccgccttc
     4621 agcagatcag cgtctccaga ttcctccaaa aaatgtttga aatggagaat gtcttcttca
     4681 tatgcttctt tcgttttttc tgaatatcct ctttcgacaa tcaaataacg caaaaatttt
     4741 tgttcccacg tggcttctgt cattttctca ccttcctttt gtcccagaga ataatttagc
     4801 acagcgttta taaaaagaca aataaattgt cagaatttaa ccaatatttc taagtttgtt
     4861 cacaattggc gcaattcctc acattttgtt tgagaaattc ttaagaaaaa cgcaagaaaa
     4921 agagcgagac tatccgtctc accctcttca tggagtttcc ttactcattt gggattgcag
     4981 ttttttctaa ttctgttttt attgcctcat tagcttttaa agctcgttgt gcaattgctt
     5041 catatcttgc ttttttgtct cgaatgcgct ctggcagttc aggaaacaga ccatagttgg
     5101 cattcatcgg ttggaaatgt tttccttccg catgagtaat gtagtaagcc atacttccaa
     5161 tagctgtttc ttgtggaaac tcgactggtt ccatttcttt tgctaagcgt gcggcgttga
     5221 ttccagcaag tagtccgctc gctgcacttt caacatagcc ttctacacca gtcatctgac
     5281 ctgcaaagaa cagatcttcg cgtttcgttg attggtaagt cggtttcagc aattctggcg
     5341 aattcataaa gctgtttcgg tgcatcacac catagcgaac gaattcagca ttttctaacc
     5401 caggaatcat ccggaaaaca cgtttttgct cgccccattt caagtgagtc tgaaagccca
     5461 cgatgttgta taaagaagct gcagcattgt cttgacgcag ctggataaca gcataaggac
     5521 gtttgccagt tttaggatct tccaatccaa ctggtttcat aggtccgaaa agcatcgttt
     5581 tgaatcctcg ctgtgccatt acttcaattg gcatacatcc ttcaaaatat ttttctttct
     5641 caaaagattt aagttctgcc acttcggcat tgattagtgc ctcatggaaa gctttgaatt
     5701 cctcttctgt catcggacag ttcaagtaag ctgcttctcc tttgtcatag cgggacttca
     5761 aatatacttt atccatatcg atcgtagctt tgtctacgat tggtgcagct gcatcataga
     5821 aataaaaacc atctgaacca ttgaatgctt tgatgctttc tgctaatgga tgagaagtca
     5881 aaggtcctgt tgctactacg gtgattcctt ccggtatttc agtaatttct tcgtttatca
     5941 ctgttactaa tggatgctct ttgacttttc gggtaattgt ttcagaaaaa gaatcgcggt
     6001 caacagctaa ggcaccacca gctggcactg ctgtttcatc tgccgaagtg attactaccg
     6061 aattcaatcg gcgcatttct tctttcaata accctactgc attagccaaa ctgtttcctc
     6121 ttaatgaatt ggaacatact agttcagcaa aattacttgt gtgatgcgcc tcagtcgatt
     6181 tgactggacg catttcatat aaacggacag ggactcctgc ttgtgcgatc tgccaagcag
     6241 cttcacttcc ggcaagccct gctccaacaa catttaccat tttcaatgaa agaacctctt
     6301 ttctattatt tttggatgtc ttcttcgtaa tctccattta cacagactac ttgtttaccg
     6361 cctttgactt tcttctcgac cagatatccg tcacattttg gacaatttct gcccactggt
     6421 ttatcccaag aagtgaattc acattctggg aaacgggaac aaccatagaa tagtctgttt
     6481 ttcttagatt ttcgttcaat gacttgtcct tcatgacata ctgggcaagt cacaccgatt
     6541 tcttttacga ttggtttcgt attccgacaa tcaggaaaat tactgcaagc ataaaacttc
     6601 ccatatttcc ctaattttat caccatcgga tgtccacaga catcacaatc gaatcctgct
     6661 ggttcatctt tgatttgaat tttttcgatt ttttcttccg cattcgtcag ttctttttca
     6721 aacggtttat agaaacgatc aaccactttg acccacgctt ccgtgccttc ttcaatttta
     6781 tccaaatctc cttccatttc tgctgtgaaa tggatatcga cgatttgagg gaagaattca
     6841 cagattaatg aattgacaat ttctcctagt tcagtcggct caaatctttt ttgtgtcaat
     6901 tttacatagt agcgtctttg gatcgtatca agtgttggtg cataagtgga aggtcgccct
     6961 accccgtttt cttctagtgc acgaatcaac gtagcctcac taaaacgtgc tggtggttga
     7021 gtaaaatgtt gttttggttc aatatcaaca gattggacta catcgccttc ttcaagttct
     7081 ggaagaatat tttctttctc ttctttgccg tcatctctac cttccacata cacttgcatg
     7141 aatcctttga atttgatttt tgaaccgttc gcaatgaaga tgacaccatt ttgttctaat
     7201 gtcactttca ttgtatctaa aatagctggt gtcatctgac tagccacaaa acgtgaccag
     7261 atcaatgtat aaagtttcaa ttgatcttta tctaaatatt gtttgagttc atctggtgta
     7321 cgaagcacac tcgttggacg cacagcttca tgggcatctt gtgcgccttg agcatttttg
     7381 atctttcggt gatcatgtct agaaaattct tttccatacg tatcttcaat aaatgctgcg
     7441 gcctctgctt ttgctgtatc ggcaatccgg gtagaatcag tacgcatgta tgtaatcaag
     7501 ccgactgttc cttgtttacc caaagtgatt ccttcatata attgctgtgc taccatcatg
     7561 gtttttcttg ttcgaaagtt taacttacgg gcagcttctt gttgcaggct acttgtagtg
     7621 aaaggattcg cagggtttct tttgcgctct ttcttttcta cttttttaac ttcgaagtct
     7681 gttccatcaa ttctagcagt gacttctttt acactttgtg catctggtaa tttctttttc
     7741 ttaccgtcga ttccccagaa atttgctttg aatttcttgc gagctttttt aaaattaccg
     7801 tcgatgctcc aatattcttc tggaacaaat tctcggatct ctttttcacg gtcaataata
     7861 atttttaaag cgacagattg gacacgtcct gcacttaacc ctttcttgac cttacgccag
     7921 agaataggac tgatcgaata accaacgatt ctgtctaagg tacgacgagc ttgctgtgca
     7981 tctactaaat ctacatcgat cgttcttggt tccttaaaag ctgctttgac tgcgtctttt
     8041 gtgatttcat tgaagaccac ccgatttttt tctttcagat ccaacccaag taggtacgct
     8101 aaatgccaag caatcgcttc tccttctcta tccgggtcac ttgccaagta aactttttga
     8161 gctttttttg ctgcggcttt caggcttttg atgacatcgc cttttccgcg tatagaaata
     8221 taatggggtt cataattgtt ttcaaaatcg atacccattt tacttttcgg taaatctctt
     8281 atatggccaa cactggccat tactttatag tttcgtccaa gatatttctc aattgtcttg
     8341 gcttttgcag gtgattctac aatcactaaa tatttatacg ccattactga atggactcct
     8401 ttccattgtc gtgttcctac tattaaaaga ggattcatac aaatcgtagc taatcatatc
     8461 cattcagaaa acgtttgtca agaaaagcaa atgaaaagta tggtgttatt ctttaaattc
     8521 tgccaagata tcttcacccg aaaccgtgca aactgcaccg tcttggatca aatgatgaca
     8581 tccggtagaa tgttctgtta aaatatttcc tggaacagaa aaaactgttc ttccaagatc
     8641 caatgcttgc tgtgctgtta tcagagagcc gctttttttc ttggcttcaa agacacatgt
     8701 tcctttagac aaagctgcga taatccgatt tctcattgga aaacaatgct ttttcgggcc
     8761 ggattgagga ggatattcac tcaaaagaag atgatcattt gcaatcacct cttgcaagtc
     8821 acgattttca gcaggataga cttgctctat ccctgttcca atgactgcga ttgtccgtcc
     8881 accatgagag attgctgctt ggtgaccgta tgtatctatc cctttcgcgc agccactgac
     8941 gatcacatat ccagcttcta tcactggttt tagtaaataa taaactgttt ttttggctaa
     9001 agcagaagtg tgtcttccac caacaacgct taacatgtta caagaaagta aagatagatc
     9061 accattataa aacagtacaa ttggcggata ggtcaagtga agcagctgag ggggatattt
     9121 gggatcaaag caagtgataa acgactgttt cgattggatt ttgccccagt tagcgtgaat
     9181 ttcctgccaa cttttgcgaa acagctcccg gtgtttggtt attttaccta tcttaatgat
     9241 gtcttcaaat ccgatttctt tataaggata ctgcatcatc cagttagcaa gtgcccattt
     9301 tccttgacta ctgattcctt ttgtataagc aagtttcaat aaattttctt ctatttgata
     9361 catcataaaa ccgcctttcg tctctctttc taataagata cgtaaaagcg gctgtttttt
     9421 attgtaaata tttttttaca ggtgcaaaac ttttacgatg gattggcgta attccttgtc
     9481 gttcaagtcc ttctaagtgt tcctttgttc cataacctgc attatgcgag aaaccatatc
     9541 caggataaag cacgtcatat tctttcatca attggtctcg atatacttta gcaatgatac
     9601 ttgcagcagc aatcgacaca gatcgtgcat cccctttgat tattttttcc tgctgaatag
     9661 gcaaatccaa ggtcatcgca tcgatcaaca aatagcttgg tacaatggac aatttttcta
     9721 ctgcttggat catcgctaat ttacttgctt cataaatatt cacatcatcg attgtctgct
     9781 gatcaacgat cccgatcccg attgccaggg ctttttcttg aacttgttga taaagaagtt
     9841 ctcgcttttt ctctgataat tgtttggagt cattcagccc taatatgatc tcatttttcg
     9901 gcaagataac tgcagctgcc acgacaggtc cagctaatgg tcctcttcct acttcatcaa
     9961 tgccggcaat ccattggtga ccttgtgcgt acccttgctt ttcaaagcaa aacatttctt
    10021 catatttttc cttaattaat gcttcctttt tcaatcgtcg ttcaaaagaa gccagtgctt
    10081 gctgcacgcc tttgcgtgga tcatttctta atgattctag tgtaggatca tctattctct
    10141 gtatgctttt caatcgttct ttgatacttt ggatggattc agtcatcact tttttgctcc
    10201 atttcttcgc aacgatccag tgtgtatcgt ccaagttttc cttgacgaat atcatgcacg
    10261 actaattcgc tgccacgatc atagtcttct ttatacccac gttttgctgt aatatccatc
    10321 agtaattccg gtgccaattt ttcttcttgc tcgattgata aaccataacg atcgctgatt
    10381 cttcctgaat aatatcgggc aaaaaagtct aatccgtaaa tcgctaaatc atctaaatgg
    10441 acaagctggt ctttgatcgc gcctgtcagc gctagttttt tgccgatttc ttcatcttca
    10501 aatttgggcc ataaaatccc tggtgtgtct aacaattcca actcattacc taaacgaagc
    10561 cactgctgac cttttgttac gccaggctta tttcctgtct gtgcaatttt cttgcctact
    10621 agtcgattca tcaacgtaga tttcccaaca tttggaatac ctaagaccat tgcccgaata
    10681 gcgcgaggct tgatcccccg agcagcatct cttgcccgtt tttctttcaa tgcttcttta
    10741 gccgcaggta ctagaccttt aattccttta ctttcttgtg ccgtgatagc taatgcaaga
    10801 tggccttgtt tacgaaaata ttcttgccac agctttgtct gttgtggatc tgccagatcc
    10861 gctttattca ataaaacaag gcgaggtttt tgctgaatga tctgatctag cattggatta
    10921 cgagaagata aaggtaatcg tgcgtctacc aattcaaata cgatgtccac atatttcatt
    10981 ttttcagaaa cttctcgtcg ggcttttgcc atatgtcccg gaaaccattg gatggtcatt
    11041 gttctctcca ttcctttcat accggaatat tccccggctt tacttgtttt tttctttttc
    11101 aatataaatt cactttttta ttataaagaa attccatcta ttagttaagt gaaagtgaac
    11161 cagtcctcat tctatcacat cttcactttt ttgatgatgc aaatttttat tttggtttct
    11221 atatatgaat ctaaattttt gacagcgttt cctaaataag agatgataga cgaacaaaac
    11281 agaaaggaga cgaaacaaat gaatagtatg gtttttgtta attttcctgt tgctgatgtc
    11341 aatcgttccg ttgcttttta tgaaaagctg ggttttaaaa aaaatgaaga attttctact
    11401 gaagaagctg gttcaatggt atgggatgac actttttgga taatgcttct ctctcatgat
    11461 ttttataaaa aatttataaa agataaagaa atagctgata ataaaaaaac aagtggtgct
    11521 ttgatttcgt ttagtgttga aaatgcggat gaagtaaaaa aatttgctca aattgcaaaa
    11581 gaaaatggtg gtactttcca cgaagtagat atgggaatgc ctgaagaaga aatgttttca
    11641 ttagaagtcc aagatctaga cggaaataca ttagaacccg tatggatgaa gatgtaagca
    11701 gataactaat ctgacgtttt ttata
//
LOCUS       DAFEIE010000077        11520 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFEIE010000077
VERSION     DAFEIE010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.080"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(68..1747)
                     /locus_tag="LP345_002398"
     CDS             complement(68..1747)
                     /locus_tag="LP345_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL1761159.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            2295..3797
                     /locus_tag="LP345_002399"
     CDS             2295..3797
                     /locus_tag="LP345_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1761160.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNLKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            3810..4472
                     /locus_tag="LP345_002400"
     CDS             3810..4472
                     /locus_tag="LP345_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1761161.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4573..4776)
                     /locus_tag="LP345_002401"
     CDS             complement(4573..4776)
                     /locus_tag="LP345_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL1761162.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(4887..6071)
                     /gene="iadA"
                     /locus_tag="LP345_002402"
     CDS             complement(4887..6071)
                     /gene="iadA"
                     /locus_tag="LP345_002402"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBL1761163.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(6228..7967)
                     /gene="yfcC"
                     /locus_tag="LP345_002403"
     CDS             complement(6228..7967)
                     /gene="yfcC"
                     /locus_tag="LP345_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBL1761164.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(8740..9354)
                     /locus_tag="LP345_002404"
     CDS             complement(8740..9354)
                     /locus_tag="LP345_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1761165.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(9960..10337)
                     /locus_tag="LP345_002405"
     CDS             complement(9960..10337)
                     /locus_tag="LP345_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761166.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(10637..11518)
                     /gene="galU"
                     /locus_tag="LP345_002406"
     CDS             complement(10637..11518)
                     /gene="galU"
                     /locus_tag="LP345_002406"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL1761167.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         3440 a         2433 c         1947 g         3700 t
ORIGIN      
        1 tatttgtttt tcgcaaaaaa agagcaagac gagcactcta tagagaggtt catcttactc
       61 tttttgttta ttttttattt cgacgttgag tagcttccat aatgactggc aagatcactg
      121 ggcggcgttt tgtttgttca aataagtaac ggcctaattg atctcggatg tcttgcttta
      181 atttgctcca ctcaaaatca ttgctttcta aatgtttctc aacgattgtt tcaatcatat
      241 tgctgctttc tttcatcaga tcacggctag cttttacgta aacgaatccc cgtgaagtaa
      301 tttgaggttt tgaaatgatt ttcttttctc gccgactgat agtgacaacc gctacgaaaa
      361 tcccgtcttc tgacaagatt tttcgatcac gtaaaacaat gtttccgata tcacctatgc
      421 ctaatccatc aatcattaca ttttctgcac ttgtagttcc tgcaacactc atacgcttgt
      481 tcttatattc cagcacgtct ccgcgtccag taatatagat atttttgtat ggcatcccta
      541 ctgcatgagc caaatctgca tgagcagcta attcacgata ctctccttga actggcacaa
      601 aatatgttgg tttcatcaaa ttgatcatta attgcaagtc attaggattg gcatggccag
      661 aaacgcgcat attctcagag atcaacttca ctgttccacc agctcgataa atgatatctt
      721 ccgttttcgc cacgatggtt tccatcgcga tgcttggcgt agtagtgata taaaccaaat
      781 ctccttcttc aatcttgaca ttacggtgtg taccgtttgc cattttttgc agagacttga
      841 tgggttcacc cattcggcca gtttctaaaa tgatcagttc ttctggatca tagtttttca
      901 tgtctttcaa cgtaacaagc agatcttcac ttggtaattg aagtttttct aaacgcatcg
      961 ctgtgcgaat aattcgttcg aaatcttgac cagtcaagac aacttttcgt tgtgcttttt
     1021 ctgctgcatc caatacttgt tgcactcgtt gcaaattact tgctacacaa gcgacgatga
     1081 tacgcccttc ccaatatttg atcgtatcaa atacttcatc tgctatttgg gcttcagaag
     1141 ctacaggctg aggattttct gcatttgccg attcacttag taaggctaag actccttctt
     1201 tgccgatttc cgccaatcgt gcataatctg tttgatacat tgggatagcc gtttggtcaa
     1261 atttaaaatc tcccgtataa acgatactac cttcttttgt tttcagattg atccccactg
     1321 aatctggtat cgtatgagtg gtacggaaaa agctcactac tgtttcacca aagtctattt
     1381 ctgtatgctc atctaccaca tggaaatcct taaatccttt ggctgcttca ttacgactga
     1441 cattcaattt tgctaactcg atcgtcaact ctgtcccgaa tactggtaca gaaatttttg
     1501 acaacaagta aggaagtgcc ccgatcgcat ctgcatgtcc atgtgttaaa aagacaccag
     1561 ctacacgatc aatgttttct tctaaatacg taaaatcagg gattacgacg tcgatcccca
     1621 acaactcatt ttcaggatat tttagcccac aatctaaaat aaaaatatcc tcgcccactt
     1681 ctgcgacata catgtttttt ccattttcac gaacgccgcc taatgggata attttaatgg
     1741 tactcacaaa cttcacctct tcttatgaca tccaagttta aagatgtcga ttttcttctt
     1801 tatctaaata tatgagccat tccaatgaag catatgcaaa atcactattt ctcaacttat
     1861 ggagaatcag caggaaaatt accagcacat ccgcgttctg acagttggat gggcatttta
     1921 ttttggatat acttcattaa caaaatggat cttttgcgaa acgctatagc cagaatactt
     1981 atataagtat tcagctgttc cccattatta tacaacaaat aaactaaatc gctagtatca
     2041 gcaattgtta gaacaactat gcacgtaaaa atccctctgt agcatctagg atttcttttg
     2101 ctattcctct ttcatttctt cttcgtcggt ttgaaacata cttttttcat tttaccacat
     2161 tttttgcaat aactatagtg actttttata tatacagaac ctcatgttga tggtgtgcaa
     2221 acagcataag atttaagcta gctttaagat aggttgtcta ttatcaaatg catctactag
     2281 gagggatgca aaatatgaat tttatgaaac gtgcatggaa aagtacaaaa gtaaaatggg
     2341 gacgttcatt gttattgttt gccgtgttca cagccattct tatttttgtg ctagctggcc
     2401 tcacgattcg aagcgctgca gaagaagcag cgaatcaagc acaaaaagaa gttggagcaa
     2461 cagtgacttt aagtgccaat cgagaagctt catttaaaaa acaggaacaa acttcttcaa
     2521 gcggttctac cactgaagaa cgtccagatc caggcagttt ttctcttaca ccagtttcct
     2581 taacggacgc ggaaaaaata gctgaattag ataatttaaa gagttattcc tttgaaagtt
     2641 ccgcctcagc tatggcaaaa gatggaataa ctgccatcac tagttctgat tcaagtgaag
     2701 acagttcaga aactactgat gcaggcggtg aacctgctgg aggaatgggc gggaatccgc
     2761 aaatgactca agcagacttt caaatcagtg gtgtgtcagc aactgcacaa aatagtaatt
     2821 tttctgatgg aacagcaaaa atcacggatg gtgaaggaat agatgacagc gacaaaggca
     2881 caaacaatgt agtcattgat tctactctag cagaaacaaa tgacctggca gtcggagata
     2941 ctttcacaat cacgagtact gaagatgaag ataccactta tgaaatgacg atcaaaggaa
     3001 tttatgaatc cagcgaaaca agcggcagta tgggtatgaa attcaacttc atgaatccgt
     3061 cgaatacact ttacacttct tacacttttg caaatgaact aaatgggaca tctgacgata
     3121 acacgataga ttctgctatt tacactctat ctgatccaga taaaatggat gagtttctca
     3181 aagaagctga gaagctgatc gacacagata catttagctt acaatcaaat gattccatgt
     3241 atcagtcaat gttggaacct ttaaacaacg tggcaagttt ttctaaaaat gttgttttac
     3301 tagtggctgt agccggtatt atcatactta ctctgatcat tatgattacc attcgggagc
     3361 gtcggcatga gttaggcgtc ttgctatctt taggagaatc cagaagtaaa atcattctcc
     3421 aattgtttac cgaagtggct atttgtatga ttcttgcatt aggagttgct tcgcttagcg
     3481 gaaacgtcgt cgcgaatgcc gtgggacagc agctacttga ccaacagaca gaaaccacga
     3541 cacaaaacca gcaagctcct ggcggtggac aaatgccagg taacagacaa gaacaaggcg
     3601 gtcaacgcga tggtcaacaa ggaaccacga ataatccatt tgctgtttct gatcaagtca
     3661 gcgaattgga aatcaatgtc aaacctgcac aattgggact attagccgga gtagcatttg
     3721 gaatcagtct gttttctgtc tttttagctt ctatagggat attaagatta aacccaagaa
     3781 aaatcctatt aaactaaagg aggaatttga tgttacggac agaacaattg ggattttggt
     3841 atcaagatcc gcaagatgcg ctttataaag atgtagaact gaatttcgaa gctggaaaaa
     3901 tgtacgctat tttaggagca agtggttctg gaaaaacgac ttttctttcg cttatttctg
     3961 gactagatgc accaaaagaa ggaaaggtat actatcaaga tcgttcactg aacaaaatcg
     4021 ggttaagaag ttatcgtaaa aatgatgtct cgattatttt ccaagcttac aacttgcttc
     4081 cttatttatc ggctctagac aacgtcatag cagcaatgga aatcactaag accaagcaag
     4141 agaattatcg acaagttgct ttagatcgac tggctcgtgt aggaattgat gaaatattag
     4201 caaaaaaaca ggtgaccaaa ctttcgggag gtcagcagca gcgagtcgct atcgttcgtg
     4261 ctatctgctg tgaacatcaa ctaatcgtag cggatgagcc tactggaaat ctagatgaaa
     4321 caacttcaca agatatcgtc aaacttttcc aagaaatcgc ccatgaacaa aatcgctgta
     4381 ttatcatcgt gactcatgag attgaagtag caaaaagctg tgatgaagtc tttgaactaa
     4441 aaaataaaaa atttcaaaaa atcgaagttt aaaaaacagg ataatgatca aataaaaaat
     4501 ccgaaccata tctgtctcgc agatatggtt cggatttttt atttgcttga ttcaattagt
     4561 aataagtggt ttttattttt tttcgtcttt tcgagaaaac ttgtctttga cttcgtcgcc
     4621 taaatttcga gctttttctt tgatgtcagc acctagtgat tgtgctttcc cttctgtttc
     4681 tttgctcttg tcgtctgttg ctttgccgta tgcttctttt ccttcaccga ctactttatc
     4741 tttcatatct ttagaacgtc cttttaaatc tgccattgtg cttcctcctc ttagtttgtt
     4801 tattgatcta ccttcagggt aacatcaaca acagatacag acaaacagaa cgctcgtttt
     4861 ctaaaaaaga tagttagagc tgttgattaa aaactttttt cgaaagtccc ccatactttg
     4921 acttcttttt cttggaccat tatttctcct ttagcgataa ctgtatcaat atcaagcgtt
     4981 tctttatcca agatacacag atctgcatca gcaccaattt cgatttttcc ttttttatcc
     5041 aatttcaata tacgtgctgg attactggtt atagctcgta aggcgatttc caaagggata
     5101 ctttcttttt gcacagcttc tttgatccct actagcaatg ccttggcact tcctactcct
     5161 aaccctagga aatgattgtt ttcatcaaaa taaggcaagc ttccttgtcc atctgaggtc
     5221 atcgtgaaat tatctaaaga aacatcttcc tcgatcaatc gtttcagtgc tttgctgaag
     5281 cgaacttcac catctgtctt ctcccaaaaa tcaggatctt cgctagcagt gaagtcaatc
     5341 gtgccaccac gtttggcaaa tgccacgcaa gcttcaaata attctggtgt gcgatttgca
     5401 tgagtaggca aaaattgtgt gatcggaatt tctgtttctt ctacgattcg tgtcaatagc
     5461 tctagctttc tttttcctcc gcctaagtgg acattgatga tcccagcttt tccggataac
     5521 atgcctccta cacgagcatc tgctactgca cgagcgaact cttcaaaact tggctgagaa
     5581 gaacggtgat cggatactgc gatttctccg attccgataa ttttatcaat tgtcaaaaag
     5641 tctttgatga tagaatctgt tactgttttt accggcaatc ggtacgaacc ttcgtataca
     5701 taagtggaga ttccttctgc ttccagacct ttcgctttgc tgatcaacgc agtcatatct
     5761 ctaccttctc cgtctgttcc caaacaaccg acaactgtcg ttacaccagc tgtagtcaat
     5821 tggctcaatg tgacttctgg cgttcgattt tgataaccgc cttctcctcc tccacctaaa
     5881 atatggaaat gacagtcaat gaaacccggg gttagtactt ttccctcacc tgaaagttct
     5941 tctacttcca ctccttcgta gccgccttct agctgttctt ctacagccaa aatcttccca
     6001 ccggcaatca gtacatccat ttttcctaag taatctggtg caaacacttc aatttgtcga
     6061 atgattttca tacatttttc ctctttcttt aagtataact gatgatagga tcttaaaaaa
     6121 taatccaaac gataggatct ttactccttt gattttaccg taaaatgacg gttcttggag
     6181 tccttatcta ctgtttggat tactttttta tttacaggtc tccagtacta ctgcagacct
     6241 attgcaatgg caatcatgat gaaaatagtt cctaaaacaa acaggaatcc ttgcatcttg
     6301 atttggaatc ttgcccattt tgcccattcg atccgtgcaa cacctagcac accaatcaag
     6361 ctggctgata cgggtgtaaa agcgtccata aaacctgaac caagctgata agcaagaact
     6421 gctacttgtc tggatacacc tactaaatct gccagtggag ccatgattgg catagtcaaa
     6481 gctgcttgtc ctgaatttga tgtaacaacc aagttgaaca aactttggaa gatgtacatc
     6541 gcccaagcac caatgacagc tggaacaccg gtcaacgccg tcccgatccc atgcaaaatc
     6601 gtattcaaag ctgaaggaac agatgcatca gatcctccca agacaagaag aatccctttg
     6661 gccataccta ctacgattgc tgtaccagct aaatcagctg caccagattg gaaagaagaa
     6721 gcgatgtcat tgactttcat tccatctaat ttgaaaagaa cagcaatgat tccagcaact
     6781 aatcccatca caaagaattg agaagcgatt tctggaatgt aatagccttt ttgagtcacg
     6841 ccccaaacga tccagacaag gacaactaac atctctaata agatcaattt atgcccaagc
     6901 atgaattttt tattttcatc agatgtcttt ttgatatgag aacggaaata atcatctgat
     6961 ttgtaagtca acgaactttc tggtttttta cggatttttt ctgcatatat catcatataa
     7021 ccagcggcta atgcagtaac aactacccac ataatcaatc ggaatgtcgc accagacaac
     7081 acggggattc cagcaatccc ttgagccacc gctacgctaa acgggctcat ccaagaggtc
     7141 gcatttccga cttgagatgc gacataagtc acggttactg ctacgatcga gtcatatcct
     7201 aacgcaatga caaatggaac catcaccatt gagaatggaa ttacctcttc tgccatcccg
     7261 aatgtagcgc caccgaatga aaaagcaaag aataatagcg gtaaagctaa acgctccagt
     7321 cccttagttt tactgataaa cgcatagata cctgcgtcga tcgctccggt acgcataata
     7381 ataccaaaag cacctccaac aacaaggatc aatgcagcga tccctacagc agatccatac
     7441 ttatctccag atactagtcc ttcaaaaaca aaatttaaga aaccaaagcc gccaaaatca
     7501 tctgttcccc atattttggc tgttttatgc aattttttag aagtatcata gatattttcg
     7561 ccgtactgat cgtaaagcac atcatctgtc aaggagattt catctagttt ttcctgcgta
     7621 agattttttt ctccgtcagc aatgactttt tccaatcctt tttccggaac atccagtttt
     7681 tcacgttctg ctggatgatc ttgcagttct tctaattgat caaacacata cgacttatcc
     7741 agctcgtaag cataacggaa ggaatcttga cgtaaaacag tacgagtact tgtttcgcca
     7801 tttgcatctt tgtattcaat atcttgcgtg ctgaactttc ctgctggaac gacaaaagtc
     7861 agtatccatg caaagatgac tacaccaaaa ataatgacat acgtatgggg tgtcgataat
     7921 ttagtgaagt cgcgtttcgg ttttcctgaa gaatttgttt tcttcaaatt tatttcttcc
     7981 tttctttttt cagtaatttt gatgaataaa aaatggataa tcaaatgaat tatacagtaa
     8041 aaatgacatt tccacatgaa taatttatta gaaaatcact tttttctatt ttgttttttt
     8101 tctcctatgt atgattattt ttttctcttt ccatttatat taagtatttt atttctctgt
     8161 ttttccttaa aattcttttt ttatttttag attagagaaa atctcgtcct gtttttttca
     8221 ttttacaatc attgaaaaat tgaatttcat tgcaaaaaaa ataataaaca cttataaata
     8281 tccattatct atccttcaat ttttgtgtat tttatttcta ttagaaaaag gtatcctgtt
     8341 ggacaatttt gttatatcag gtaaacttca ttgcaataat gataacaaat gtactataat
     8401 tactttgtaa agagttttgg ggaagactct ttcatcaacg tgtattaaga gacaagaaag
     8461 aatccatatg gattctttct tgtctctttt tccactactt tttatttttc tgacactaca
     8521 tattcttata actcatttct cataactgtg aaacaactta taaaaataac aaactttaaa
     8581 caaaacaagc ttaaaatcaa agatgatcca tcttaaaata actaaaacaa aaaaagtagt
     8641 cgttgttaat cctcattaat aatcgttttc tttttttcaa acgctccatt tttatgtgga
     8701 acattatttt tttaaggaac tttgtcaaca tgtggataac tattttccac ttgtgtcctg
     8761 gactagctgt tttgctgtaa aatacaaaac ttgctgcagc aaaaagatcg ttgcaagaga
     8821 ggctgttccg cagatcgctg gatctagatt tggcaaagtc aagactgcat catgtaaatt
     8881 ggcgtggttg tccaaaacca aatcagcaaa ttcaaataat cgcaaaccac tgctatgttg
     8941 cgatttgata cttcgtgaca aatcaaatcc agtaacaatg attaatggat gaccattttc
     9001 tttgatccac tgagctagtt cgatgattgc cgggtttctt ccttcattcg aaagaagaag
     9061 aaaaatgtct tctgatttga cagaaagctg atcaataatt gcctgtcctg caccttctag
     9121 cgtttcatag acacctccgg ctggattttc aatcaatata cttggtacaa gatccggggt
     9181 ttgatcccaa aattcaaatg ctacaccact tagtgtgcgg ctagcatata tctgcaatct
     9241 accaccttga ttaatttgtt tcgcgatcca agtgccagct tgaagcatca gcggctcttc
     9301 tatccttaat ttctcttcca attggtgata atagtcaaaa taacataaac tcatttatct
     9361 ctcccgccta gctatacttg acatgaatag aaacagctgc ctaatctaag gaagtacata
     9421 aaaaaacagt agttagacag taacacatgt ggtctttgct gtttcaaaca caaaaaaggc
     9481 attgaacgaa tacgcccaat accttgacat agcaaataaa acaacgtgca gaccatggaa
     9541 aatatctaca taggggtaga attttcaccc tagattaggt acaataaatt aggtcgatgc
     9601 actgcattga ctatggcaaa atgatcggtc agggtgtatg tgtgtgactg gtcattccct
     9661 gattcttagc gccaactaag ggtcagggag ccttttttta ttcagctgtt tctatctgaa
     9721 tttattgtaa gtaatctctt atccaagtgc aagcaagaaa atacaaaaaa acattggtat
     9781 gatttatata tatataaata acataaaaaa aggaatggct tatcccgata caacaagcat
     9841 tcctttaaaa aagattcttt tatataagtg aaaaaagctt ttttccacca attaaataaa
     9901 tctctcatct caatagttta tccattattt tatctttttt tgcgtatacc tactaaatat
     9961 taccgtcttc ttctcgttct tctactttgt tcgagagaat ctgtactaga aaaagtagtt
    10021 gtatgtctac cttttctgcc tatccgagac tttcttttca tatatgggat ataaatgatt
    10081 agatacagta cagcaaaaaa taaagcaaat acgcaagctt cccaactacc taacgccaat
    10141 tcaaccatca aggtagcaac cccaacggat gctgcatacc agataaaaat cagaaacgtt
    10201 tctttttttc tgaccatgcg aaacatgata aatagactaa taagcaatag tggcaacaca
    10261 aatatccaat tgcttccttc catcagccac ttgagtatat caagcagcga ctgtgcaaca
    10321 gcgactaatt ttcccatagt gaacacacac ctttttttat aattaaaaaa ttcgcctttt
    10381 tattctacta tgaatcttct ggcttggctt tcatttctct tatgtaatca ttttctttta
    10441 tacaacttaa aaaaaaatta aaccattagc ataatatttt ctgaatctat tcacgaaagt
    10501 ctttttctat ctttcgtttt ccacgactca actgatctag agtcaaaaaa ctaaaacgac
    10561 agttgcgcaa atgacgcaca agctgccgct ttaataacaa atagcctttc attctcagca
    10621 ggccacttat ttccagttaa ctttctgttc ttagcttttt actcaactgg ataatatatg
    10681 cacttaatga agtcccaatt tccgaatgtt gaagtccata ttcaatattt gtcttcatat
    10741 atcctaactt atcgcctacg tcgtatcttt ttcctttaaa ctctctcgca tagaccgcct
    10801 ctgtctggtt aagagtctga agtgcatccg ttagctgtat ctcgtttcct gctcctggtt
    10861 cttgagtttc taatatctca aatattttag gagtcagtag ataacgtccg ataatggcta
    10921 aattacttgg tgcttttccc atttcaggtt tttctacaaa cccttttact ctgcaacgac
    10981 ccttttcgct atctgtttta ggatcaataa ttccgtattt agatgtttca ttttctggta
    11041 cacgcatgac ggcaacagcg gaagcttgtg tttcttcata atccatcatc aattgttgag
    11101 tcaatgggat atcatctttc atcaaatcat cccccagcat gacgacaaac ggttcatttc
    11161 ctataaatgc ttttgcttga agcacggcat cccccagtcc tcttggatga gattgacgga
    11221 tgaagtgaag attgacttga gtcgtttctt caactaaagc gagtaattct gttttttcct
    11281 tttcccgcaa attgttttcc aattcgatat ttgcatcaaa gtgatcttca atgggtcttt
    11341 tttcttttcc cgttacgatc aagatgtctt cgattcccga atccaatgct tcttccacaa
    11401 taaactggat cgttggttta tccacgattg gaagcatttc ttttgccatg gcttttgttg
    11461 ccggcaaaaa acgtgttcct agcccagcgg caggaatgac tgcttttttg accttcactt
//
LOCUS       DAFEIE010000078        11378 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFEIE010000078
VERSION     DAFEIE010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11378
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.081"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            191..709
                     /locus_tag="LP345_002407"
     CDS             191..709
                     /locus_tag="LP345_002407"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL1761168.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            837..1520
                     /locus_tag="LP345_002408"
     CDS             837..1520
                     /locus_tag="LP345_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBL1761169.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1829..1902
                     /locus_tag="LP345_002409"
     tRNA            1829..1902
                     /locus_tag="LP345_002409"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1863..1865,aa:Arg,seq:tct)
     gene            2061..2420
                     /locus_tag="LP345_002410"
     CDS             2061..2420
                     /locus_tag="LP345_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBL1761170.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2543..4174
                     /locus_tag="LP345_002411"
     CDS             2543..4174
                     /locus_tag="LP345_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBL1761171.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4236..4877)
                     /locus_tag="LP345_002412"
     CDS             complement(4236..4877)
                     /locus_tag="LP345_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL1761172.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5063..5139
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5159..5467
                     /gene="rplU"
                     /locus_tag="LP345_002413"
     CDS             5159..5467
                     /gene="rplU"
                     /locus_tag="LP345_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBL1761173.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5494..5838
                     /locus_tag="LP345_002414"
     CDS             5494..5838
                     /locus_tag="LP345_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBL1761174.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5851..6144
                     /gene="rpmA"
                     /locus_tag="LP345_002415"
     CDS             5851..6144
                     /gene="rpmA"
                     /locus_tag="LP345_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBL1761175.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(6237..7385)
                     /locus_tag="LP345_002416"
     CDS             complement(6237..7385)
                     /locus_tag="LP345_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1761176.1"
                     /translation="MAMIKQYKKKNGEKAWYFKTYLGIDPLTGKKKYTTKRGFRTQKE
                     AKTALSRLELELQKTGMPTSTNTTFKEAAELWLESYKKTVKESSYSRTKIIFNKHIYP
                     KFGNIKLSKINTAYCQKVVNDWSEKGTSKQYPLFINYMNKVFKYAINIGLTSDNPTLN
                     LLIPKPQIKTEKKLKLYTKEQLELFLNEVSQEQNPYFKNRDYTLFRLLAFSGCRIGEI
                     LALTWDNINFKTNEMAIKKTVARSDKYYISETPKTKKSNRIIYLDEKTIKQLKFWKLE
                     QRKYLFQLGFTKANYLFTNDENNFTINQSVAERYNIYRERAGLPYIGLHGFRHTHASM
                     LYEAGADHKEVQERMGHANIKTTMDTYTHITNSKKEETTQKLTNYINF"
     gene            complement(7397..7708)
                     /locus_tag="LP345_002417"
     CDS             complement(7397..7708)
                     /locus_tag="LP345_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761177.1"
                     /translation="MIYTEFKEWLEKNTTGYETFIIKATNYQIEKNKNRPQKKRWDDK
                     KIDKAVLEMWKQVVTNLYQTIRKEKGVPLINGKEIWLEFIEEQGLIEFFNDSMTELEF
                     E"
     gene            complement(7762..8157)
                     /locus_tag="LP345_002418"
     CDS             complement(7762..8157)
                     /locus_tag="LP345_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL1761178.1"
                     /translation="MMLNELGVKVEERENLDADGHYVACMNTIVIKANLSKYRRQRTL
                     LHELGHASKHHDNYFLYNLAFSLHSKMEYEADRFMIEKLLDRYIAKSELEPHNINYMK
                     FIEDNNLSVRFEPLVKELLKARIYCYAAL"
     gene            complement(8185..8532)
                     /locus_tag="LP345_002419"
     CDS             complement(8185..8532)
                     /locus_tag="LP345_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1761179.1"
                     /translation="MTAFDRLKSLCDSQGISVNDLEEKLEIGKNSLYSWKKNIPKGTN
                     LIKVADYFHVSTDYLLGRTDDPNISVASEKRKLTVEEALASVMSSDGKPLTDNDRQIL
                     TELIEAYIEKKYK"
     gene            8858..9634
                     /locus_tag="LP345_002420"
     CDS             8858..9634
                     /locus_tag="LP345_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL1761180.1"
                     /translation="MNTPQIFNFEQHEVRTVTIHDEPFFVGKDVAKVLGYQNGSRDIN
                     RHVDVEDRQNYQNGTFESPRGLTIINESGLYSLILGSKQPNAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATKLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMRQGYTKSHTTEIPK
                     SDGGTKVVMNTKWTQKGRLFIYESLKKEGYIPEIDLLEER"
     gene            9637..9849
                     /locus_tag="LP345_002421"
     CDS             9637..9849
                     /locus_tag="LP345_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1761181.1"
                     /translation="MSQDFILKVRVALATHDKSQAWLAEKLGISTAYMSDIMNGRRKP
                     DKQIKPIEAVLAELEKEKNYANNNSR"
     gene            9827..10111
                     /locus_tag="LP345_002422"
     CDS             9827..10111
                     /locus_tag="LP345_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761182.1"
                     /translation="MQITIPDNLVVSELTTQITNAVLNSLEERLHLMNKSVELPPYPN
                     KSEVKKVLGIGDDKLTHWINLGLKTQQWSKLDIRIERSELQRFLKENFEF"
     gene            10132..10320
                     /locus_tag="LP345_002423"
     CDS             10132..10320
                     /locus_tag="LP345_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761183.1"
                     /translation="MSYTLQQEHQILRLIKQRRKQLQDDREALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            10317..10490
                     /locus_tag="LP345_002424"
     CDS             10317..10490
                     /locus_tag="LP345_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761184.1"
                     /translation="MKKTDTLFIGFILGLLVIVAHQSIIGGSLFAALMVLINLLDSKE
                     RSNYGTRRSAKNR"
     gene            10646..10885
                     /locus_tag="LP345_002425"
     CDS             10646..10885
                     /locus_tag="LP345_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761185.1"
                     /translation="MENELSTLDQYLADPDWGKSNLQLVANKYEKSIDEAIVALTDAA
                     SITADDSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            10891..>11378
                     /locus_tag="LP345_002426"
     CDS             10891..>11378
                     /locus_tag="LP345_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761186.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIGATINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GA"
BASE COUNT         3672 a         1850 c         2201 g         3655 t
ORIGIN      
        1 ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat aaaaaatgag
       61 ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca tttttacagc
      121 tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat aaagaaagaa
      181 gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa cgttgattat
      241 atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt tgactcctta
      301 tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga tatatgtacg
      361 accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg aaaattcagg
      421 aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag atttttatac
      481 aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa atattatcgg
      541 tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg catttgcatg
      601 gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag catggaatac
      661 ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag aatgttaaaa
      721 acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga gaaaacactc
      781 atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg agtagtatgc
      841 gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt atgcgtaccc
      901 agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat gtagcagaag
      961 taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga cagcttcagc
     1021 ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc atggccacga
     1081 caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg atcgagaaag
     1141 ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt gaaggtcaag
     1201 cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg gatagtgcaa
     1261 aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa ggtggcgttt
     1321 tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa gagattcccc
     1381 gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg atggatcatc
     1441 ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg acaaaggaat
     1501 cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg attgaatcga
     1561 gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta aaggatacag
     1621 gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc aattgataac
     1681 cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag ttgggccaaa
     1741 ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa tttaattatc
     1801 tataattatt gatgttccgc tgattcttgt catagtagct cagctggata gagcatccgc
     1861 cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa ccgttagaaa
     1921 ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt ttcaaaggca
     1981 aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa ataaaactca
     2041 tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact ctagttgcaa
     2101 ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac acgacaagta
     2161 gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca ttgtttaaga
     2221 accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct tatctttctt
     2281 ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt gcattatatg
     2341 gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct ctgttggcat
     2401 tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag gaaactttgt
     2461 gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt ttagaaaatt
     2521 tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa aaaaagaatt
     2581 ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca cagtagctgc
     2641 tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg cggccgcagg
     2701 tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg gtttttatca
     2761 aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg caacaaaggg
     2821 aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg cagcaggact
     2881 tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg ggtttacttc
     2941 aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg ttcactcgga
     3001 aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc cgataaacac
     3061 agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc caaaaaaatg
     3121 ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag ttatgctatt
     3181 gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca gtagtaatcg
     3241 tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc cagctattag
     3301 cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg gccgaatggc
     3361 aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa atctgttgct
     3421 tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg tggccatcaa
     3481 atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac tgctctccat
     3541 gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag gtgttttgat
     3601 tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta ctaataaata
     3661 ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct ttgatttaag
     3721 tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca aaagcgctgc
     3781 tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag aaacggaaaa
     3841 gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt cttcagaaaa
     3901 actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct ccatgcgagg
     3961 cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag aaaaagcaga
     4021 gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa aacaactttc
     4081 tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg cgttgacagc
     4141 tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac agacaagact
     4201 gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa aagtgaagct
     4261 agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa aatagctgct
     4321 ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc atccttttgt
     4381 tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt aaccgtatat
     4441 tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa ttttggctgg
     4501 accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga acgagtaggt
     4561 gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg atgagtcacg
     4621 cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt taagccagtt
     4681 gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac atgcgtatca
     4741 atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag aggtccttgc
     4801 ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc ttgtatcagt
     4861 tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat aaaagaaaca
     4921 caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt attgcttgaa
     4981 tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt ctggtaagct
     5041 agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta ataagcacag
     5101 catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc tttatagcat
     5161 gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac aagcaatcta
     5221 tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag ttatcttagt
     5281 aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg ttgaaggtac
     5341 tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac ctaaaaaaca
     5401 ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg acgcgatcaa
     5461 cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt taagcgaaat
     5521 gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg tccttatgga
     5581 agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa cgggattgcc
     5641 tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg ttatctttat
     5701 accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat tctattagaa
     5761 aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat ccaaattaaa
     5821 acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct acaattattt
     5881 gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc aaaacgtcta
     5941 ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta ccgtcaacgc
     6001 ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac tttatttgca
     6061 aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca agtgtctgtt
     6121 tatccagtag ctcaagaagc ttaataaata aactgctcta tctcttgtgt agcaagggat
     6181 ggagcttttt tgtaaattat gggatttttt ttgaccatac ttttgaccat actttcttag
     6241 aagttaatat aatttgttag tttttgtgtt gtttcttctt ttttgctgtt agtaatgtgt
     6301 gtatatgtgt ccatagtagt ttttatattt gcgtggccca ttctttcttg gacttctttg
     6361 tgatctgcgc ctgcctcata tagcattgat gcatgtgtat gtctaaaacc atgcagaccg
     6421 atataaggta agccggcacg ctcacgatat atattgtatc tttctgccac tgactgatta
     6481 attgtgaaat tattttcgtc attggtaaac aaataattag ctttagtaaa tcctaattga
     6541 aataagtact ttctttgttc gagcttccaa aattttagtt gctttatagt tttttcatct
     6601 aaataaatta ttcgatttga ttttttggtt ttaggagttt cagatatata atatttatct
     6661 gaacgagcta cagttttttt aatggccatt tcatttgttt taaaattaat attgtcccaa
     6721 gtgagtgcta atatttcgcc gattctacat ccgctgaatg ctaatagtct aaagagcgta
     6781 tagtctctgt ttttaaaata tggattctgt tcttgagata cttcatttag aaataattcc
     6841 aactgttctt ttgtatataa ttttaatttc ttttctgttt taatttgtgg ctttggaata
     6901 agtaaattta atgttggatt atcagatgtt aaaccaatat ttatagcata cttaaaaact
     6961 ttattcatat agtttatgaa aagagggtac tgctttgaag ttcctttttc actccaatca
     7021 tttactacct tttgacaata tgccgtatta attttagaaa gcttaatatt tccaaatttg
     7081 ggatatatat gtttattaaa gattatttta gtccttgaat atgaactttc ttttacagtt
     7141 tttttgtagc tttctagcca taattctgct gcttctttga aagtagtatt tgtacttgtg
     7201 ggcattcctg ttttttgtaa ttctagttct aacctagaaa gtgctgtttt tgcttctttt
     7261 tgtgttctaa atcctcgttt agtagtatat tttttctttc cagttagcgg atcaataccg
     7321 agataagttt taaagtacca tgctttttcg ccatttttct ttttatattg ttttatcatt
     7381 gccatcaata ttacccctat tcaaattcta attctgtcat gctatcattg aaaaattcga
     7441 tcagtccttg ttcctctata aattcaagcc atatttcctt cccgttaatt aatggaactc
     7501 ctttttcttt acgaattgtt tgatacaagt tagtcacaac ttgtttccac atttctaata
     7561 cagctttatc tattttctta tcatcccagc gttttttttg gggtctattt ttgttttttt
     7621 caatttgata attagtagct ttgatgataa aagtttcgta tccggttgtg tttttttcta
     7681 accattcttt gaattctgta tatatcattt ttgttcacct ttctattttt gaacgtatgt
     7741 tctttttttg cttaaaaaat tttaaagggc tgcataacaa tagatgcgag cttttaataa
     7801 ttctttcaca agtggttcga agcgaacgct taaattatta tcttctataa atttcatgta
     7861 attgatattg tgtggttcta attcagactt tgcaatatat ctatctaata atttttcaat
     7921 catgaagcga tcagcctcat attccatttt tgaatgtaga gagaatgcta agttatataa
     7981 aaaataatta tcatgatgtt tagaagcgtg tcctaattca tgtaataagg ttctttgtct
     8041 tctatactta gataaattag cttttattac tatggtattc atacaagcaa cataatggcc
     8101 atcggcatca aggttttcac gctcttctac cttgacacct agctcattaa gcatcatttc
     8161 aatttgactg tccaaccgac tcacctactt atattttttt tcaatatacg cttctattaa
     8221 ttcggtaagt atctgcctat cattatcggt gagtggtttt ccgtcactgc tcattacaga
     8281 tgctaaagct tcttcaacag ttagttttct tttctctgat gcaacactta tgttgggatc
     8341 atctgtgcga cctagtaagt aatctgttga aacatggaaa taatcagcaa cttttattaa
     8401 attagttcct ttgggtatat tctttttcca agaataaagt gaatttttac caatttctag
     8461 cttttcttct aaatcattta ctgaaatgcc ttgactatca caaagtgatt taagcctgtc
     8521 aaaagctgtc atatcaagtt tcctccgttt cgctaacgaa gagtattaaa actagagcta
     8581 aaaaaatcct tttttcggct tgacaattaa aactagtttt aatatactgt attcgtaagc
     8641 taatttaata agctaacaag caataagaaa gacaccttat aaaataaaca aattcgaggt
     8701 cggcaaactt agaatgctaa tttacaaggt aattctgtgc ttatttaact gtgatttaat
     8761 tttaaatcta gttttaaaaa aagtcaacaa aaattagcta attttattag cttacaaata
     8821 atcaaataaa ctatatcaaa gaaaggaatg aacaaaaatg aatacaccgc aaatttttaa
     8881 ctttgaacaa catgaagtaa gaacagtaac aatacatgat gaaccatttt ttgttggaaa
     8941 agatgtggct aaagttctag ggtaccaaaa tggtagtaga gatattaaca gacacgtcga
     9001 tgtagaagat cggcaaaact accaaaacgg tacttttgaa tcgcctagag ggttaactat
     9061 tattaatgaa tcaggtttgt actccttaat tttaggaagt aaacaaccaa atgctaagaa
     9121 atttaaacgt tgggtgacta gcgaagtgtt gccagcaatt agaaaacatg gaggttatct
     9181 aactccagaa aaagtagaag aagctttgct taatccagat acaatcattc aattagcaac
     9241 taaattgaaa gaagaacgta ctggaagatt aatcgcagaa caaaagattg cagaatacga
     9301 acctaaaatt tcatatttag atagcatatt atcttctaca gattcagtaa caattagtca
     9361 gattgcagca gattatggga tgtctccaca acagatgaat aaactacttc ataaactagg
     9421 tattcagaaa aaagtaggca atcaatggtt attatgtaag aaacatatga gacaaggata
     9481 tacaaaatct catacaactg agattccgaa atctgatggc ggaacaaaag ttgtgatgaa
     9541 tactaaatgg actcaaaaag gacgtttgtt catttatgag tcgctaaaaa aagaaggata
     9601 tattccagaa attgatctat tagaggagag atagttatgt cgcaggactt cattttaaaa
     9661 gtgcgtgtgg cgctagctac gcatgacaag agtcaagctt ggttagctga aaagcttggt
     9721 atttcaacag catacatgtc ggatattatg aatggacgta gaaagccaga taaacaaatc
     9781 aagccaattg aggcagtgct agcagaatta gaaaaggaga aaaattatgc aaataacaat
     9841 tccagataat ttagtagttt ccgaattaac tacacagatc acgaatgcag tgcttaattc
     9901 tttggaagaa cgattacacc ttatgaataa atcagtggag cttcctccat atccaaacaa
     9961 atcagaggta aaaaaagttt taggcattgg tgatgacaaa ttaacacatt ggataaactt
    10021 aggcttaaaa acacagcagt ggagtaagtt agacatcaga attgaacgat cagaactcca
    10081 aagatttttg aaagaaaact ttgagttcta aaggcaaagg agaatgattt tatgtcctac
    10141 acattgcaac aagaacatca aattctccgt ttgattaaac aacgcaggaa acaattacaa
    10201 gatgatcgtg aagcgcttag aaaagccgat gagctatcag atagacaagc tgaactaatc
    10261 gcttctgaac ttgaggattt gagaatgcta gaaataaaaa atagggagat tagattatga
    10321 agaagacaga cacacttttt ataggattca tcctagggct attagtgata gtagcacacc
    10381 aaagtattat cgggggaagt ttgttcgcag cattgatggt tttaatcaat ctgcttgatt
    10441 caaaagaaag gagcaactat ggcacgagaa gaagcgctaa aaatcggtaa agtgattgct
    10501 gataattggt gggcaaatag ccgttctatt attttaagca agcaacatat cgaaaagaaa
    10561 aaagcatggc aacaaataaa aaagtgactc cgccgaccaa agcaatgagt cactcaaaaa
    10621 atcataacta aggagatttt aacatatgga aaatgaactt tccactctag atcaatattt
    10681 ggccgatcct gattggggca aatcgaattt acaactggtt gctaacaagt acgaaaaatc
    10741 aattgatgaa gcaattgttg cattgactga tgcagcttcc ataaccgctg atgacagtaa
    10801 atggaccaag agagacttgg gcattctaaa acgaggcgtt aattggcttg aagatcagta
    10861 cagagaagaa acaaaagaga agtgatatga gtgtttaaac cactaataga ttcatactcg
    10921 gcggtactaa agaaatttaa aggtaacgac attggtgcaa caatcaacga agaagtaaat
    10981 atcgaacggc tgaaaacgat gtatgacgga tatgatggcg atcgagtcat tgaaattcgc
    11041 tttattgatc cacgacggtt cacagtacag caaagaaact tcatctatgc gctcataggc
    11101 gatattttca tcgatacagg catgccaacg gacttctgga aggaattctt ctacttccgt
    11161 tttgaaggtg tcacagggcg cgaaataagc ctcaaagacg aatcgaatac aaccgtgagt
    11221 gatgccaata tcttagcgaa tatcatccta gatttcatct ttgaacatca tattcctttc
    11281 aaagaaggat atgagatttt accagcgaat caagagtatt acttctacaa atgcattaca
    11341 aaaagagtct gctgcatctg tggcaaaaca ggagctga
//
LOCUS       DAFEIE010000079        11107 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFEIE010000079
VERSION     DAFEIE010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.082"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            258..533
                     /locus_tag="LP345_002427"
     CDS             258..533
                     /locus_tag="LP345_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761187.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            546..2624
                     /locus_tag="LP345_002428"
     CDS             546..2624
                     /locus_tag="LP345_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBL1761188.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2784..4670
                     /locus_tag="LP345_002429"
     CDS             2784..4670
                     /locus_tag="LP345_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1761189.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4682..5629
                     /locus_tag="LP345_002430"
     CDS             4682..5629
                     /locus_tag="LP345_002430"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBL1761190.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5649..6176
                     /locus_tag="LP345_002431"
     CDS             5649..6176
                     /locus_tag="LP345_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1761191.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6239..6892)
                     /locus_tag="LP345_002432"
     CDS             complement(6239..6892)
                     /locus_tag="LP345_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBL1761192.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7024..7866
                     /locus_tag="LP345_002433"
     CDS             7024..7866
                     /locus_tag="LP345_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1761193.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8024..8920
                     /locus_tag="LP345_002434"
     CDS             8024..8920
                     /locus_tag="LP345_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL1761194.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8923..9636
                     /locus_tag="LP345_002435"
     CDS             8923..9636
                     /locus_tag="LP345_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBL1761195.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9656..10174
                     /gene="msrA"
                     /locus_tag="LP345_002436"
     CDS             9656..10174
                     /gene="msrA"
                     /locus_tag="LP345_002436"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL1761196.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10171..10398
                     /locus_tag="LP345_002437"
     CDS             10171..10398
                     /locus_tag="LP345_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBL1761197.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10550..11101
                     /gene="lepB"
                     /locus_tag="LP345_002438"
     CDS             10550..11101
                     /gene="lepB"
                     /locus_tag="LP345_002438"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL1761198.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
BASE COUNT         3853 a         1876 c         2291 g         3087 t
ORIGIN      
        1 atttttgtcg cagccccatt tttttgttgt gataaaagaa caagaaaggc aggaatggga
       61 aagtaaacat ccttttgtca gaaactttta tctttcttaa gttttacttg atatctgata
      121 ctatttggaa tagaatgagg cgttgaaaaa tttatggaaa tttctaacta gcaataaacg
      181 atgaaacaat gaaatatttt tcatccaaaa agaactttgc tataatgatg gaagtttgtg
      241 tataggagat ctggaaaatg agagagagtt ttgaacaaca aaaaaaactg ttgcatgatc
      301 gctatggcgc cctttcgatg gatgaccgcc gtcaaatact ttgtaagttg cgtaaaagaa
      361 atatattgat gtatcgtcag ttggaacgtc tgaaacatga tctgcttcgt ttggagtcaa
      421 aacgtgtaca gtgtgaatta gaggggaacc aaacacaggt tgaagtagtc gaaaccaaaa
      481 ttttaaagaa aaaagaacaa tttttaaaaa tgcttacaca aaataaaaaa taaaggggat
      541 ggacgatgga atttgctgag ttagttattg tatttgcagt aacgatcacc ttatcgaaca
      601 tagctagccg cattttgcca atgattccag ctccactgat ccaaattttc cttggagtgg
      661 tattaggtct gacagagtgg ggacaatcaa tcgattttga acctgaattg ttcttagtta
      721 tgattattgc accattgtta tttagagaag gagaaaaagc agatatttct tcgattctca
      781 aaaatttcgg gacaattttg ttcttggcat ttggaggagt cattttgacc cttgtcgggg
      841 taggtgcgac gttatcattc ctgttgccaa gtgtcccact tgctgcctgc tttgcttttg
      901 gagcagcgtt aggtccgaca gatgcggtag cagtcagttc tctttctgga cgagtgaata
      961 tccctaaaaa ggcgatgcat attttggaag gagaaggtct tttgaatgat gcatctggtg
     1021 ttactgcctt ccagtttgct cttggtgcgc tgatcaccgg atctttttca gcagtaaacg
     1081 cggggatgag tctagtagtt tctagtattg ggggagcttt gatcggcttt ttgcttgtct
     1141 ggttcaaaca aaaaataatt catttgatcg aaaaagcatc agcacaagat gtcacagggt
     1201 atctgctgat cgaacttttg cttccttttc tagcctatgt attggcagag gcatttgatg
     1261 tatctggaat cattgctgca gtggcagcag gtattctcca agcttctggt tttaggaaaa
     1321 tctctgtgtt tgatgcagaa ttgtcgagct tgtcccacag tacatggaca actattgctt
     1381 ttacactgaa tgcattagta tttatatttt taggaatcga attgacgcaa gtgttctcgc
     1441 cagtatgggg agacggttta tatccaaacg gtcttttatt agcgattatc gtattaatct
     1501 ctgtcatgct ttttgtgatc agattcattt ctatcagtct tttttatgta ttcaaagatg
     1561 gcagtaaaaa gttcaaaaaa cagttgaacg agatcttgat cttaacattt ggcggtgtaa
     1621 agggaacagt cagtttggct acgattttta ttttgccatt ttcaatcaat aatatgatgt
     1681 tttaccagcg gtctttgctt ttgtttctga cggcgggtgt catcttagtg actttggtca
     1741 tagggatcat tgtcttgcct atgctgacgg aaacagagga agcgaaaagc acggatttga
     1801 atgctttgat gattttagaa gaggtcgttg aagttttgcg aaaagaaata aaggaaattg
     1861 atcgtaatac aaaagaattt ttagccactg aagcagtgat agaaaattat caagaacgga
     1921 tacgtgatct gtacttggaa gatttaaccg atgatgaaaa gcaagaagta caagaaatac
     1981 aagcactgat tttgtcgatc gaacgggatg gattggatga aagttatcgt tcgggcaagc
     2041 tttcttctaa tggttatcgt ttttactccc gttttctttc tcgattcgaa cattctatca
     2101 caagccagat tttgtctttt atcggctttt ggttcattgt tgtccgtagg ttaatgcgaa
     2161 tcgttctcca tccgaaaatg ttttggcaaa gaagatatgc tgatcgtcag acatttatta
     2221 gtgatgaaga tatccaagaa atcagagaga catatcaaaa aaatactcag ttgattattg
     2281 aaagtttaga taacttgact gatatttatg atgaaacgat ggttcaattt tttatccagc
     2341 aacgcaaact tgaaggaata aaaatgaact cggggaattt gatttcttcg tggatgatcc
     2401 agcaagatag tctgtttacg aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca
     2461 ttgatgaata cgaagttgct gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga
     2521 atatcaattt gttagaatct tatacgatga acaaaccatc tgataacttt tctttccgat
     2581 ttgcgtttcg agcaaagtca aaaaaaacga gtccaataaa ataaaaaggt aaaaattttc
     2641 aagttttata aaaaacaaaa catatcagaa caggatcgaa tcggtcctgt tctttttttg
     2701 agaacacaaa aagaacaaat accaaaaaaa ttttcctgaa gttcactatt tttatgatac
     2761 aatatccaag ataaggaggg aacatgttga aagaattaaa agtaactgac ctcaaaaaaa
     2821 cttatggtga aaaagatttg tttgaccaga tttctttttt ggtccacgaa aaagaccgta
     2881 tcgggttgat tgggacgaac gggacgggta aaacaagtct cttaaatatt attgccggta
     2941 tcgatagcag cgacggtgat cggcaaacag tgttttatcc aactgattac cgtattggtt
     3001 atctttctca agcagctgaa ttttccgatg aattaactgt tctccaagca gtctttcaag
     3061 gaaacagccc cttgatccaa actgttcgag catatgagga agcattgatc gaactagggg
     3121 aaaacggaga agaccctgat gtgcaaaaac gttatgctaa agcagaagaa caaatgaata
     3181 aagaagatgc ttggactaca gataccaacg caaagattat tttgcaaaaa ttaggaatca
     3241 gtgaattaga taaaaaaatc agtactttat caggtggtca gaaaaaacga gttagtctgg
     3301 cgcaagtgtt gattgatgaa cccgatttac tattactaga cgaaccaaca aaccatttag
     3361 attatgaagc gatcgagtgg ttggaaaact atttgaaaca ataccgtggc gcactattga
     3421 tggttaccca cgatcgttat tttctagata gagtagcaaa ccgaatcttc gaactttcat
     3481 ttggaaaatt atacgagtat aaaggaaatt atgaagctta cgtcttagaa aaagcagaac
     3541 gtgatcgtgt agaagtagaa caagaagaaa agcgcaagcg gctttataaa caggaattag
     3601 cttggatgag ggctggcgta caggcacgtg gcaccaagca gcaagcacgg atcaaccgtt
     3661 tcgaagatct aaaggagaac ttgtaccaag taaaccaaga agatgattta gagctgaacc
     3721 tagcgacaca acgtttaggg aaaaaagtac tggaaatcaa agatggcagt taccgtataa
     3781 atgaccaaac actgctagaa catttagatt tattgattca atctcgggaa agactaggta
     3841 ttactggtaa aaatggtgcg ggaaaatcga cattgcttaa tattctagct ggcagaattc
     3901 ccctggatag cggtacaatg tctatcggtg aaacggttca tcttgcgtat tatacacaag
     3961 aaaatgaaga aatggcacca gataaacgga tgattgctta cttacaagaa gctgctgaag
     4021 aagcaaaaac agcagatggc agtcaaatcg gagtagcaga attacttgaa cgatttttat
     4081 ttccaagatt tatgcatggg acactgatag gcaaactttc aggcggagaa aaacgccggt
     4141 tatttttgtt gaaactgctg attcagcaac ctaatgtttt attattggat gaaccgacca
     4201 atgatttgga catagcaaca ttgacgattt tggaagatta ttttagaagt tttccaggtg
     4261 ctgtgatcac tgtttcccat gaccgttatt tcttggacaa ggtagcagat aagttattag
     4321 tattccaagg aaacggaaaa caagaacttt attacggaaa catgtccagt tatttactga
     4381 agcaaaaaga gacccagcag cctgctgaaa aagcgaaacc aaaaatacag agcaaggaac
     4441 ctgctgaaaa gaagaaatta tcttacatgg aacaaaaaga atgggaaacg attgaagatg
     4501 agattgcaga acttgaagaa aaaatctcat tgctccaaga agagatgaat catcaaggag
     4561 ataatttcac tcgattacaa gaattgcaaa acgacgtatc tgaaacagaa gcacaacttg
     4621 aagaaaaaat ggcacggtgg gaatacttga gtgaatgggt agaagattag gaggaaaaag
     4681 gatggaacaa gcgtatcttg acttaggaag aaaattgttg gaagaagggc atcgtaaaga
     4741 agacagaaca ggcacaggca cattaagctt attcggatac caaatgcggt ttgatctgca
     4801 aaaagggttt cctttgttaa caacgaaacg agtacctttt ggattgatca aaagcgaatt
     4861 gctttggttt ttaaaaggag atacgaatat ccgctatcta ttacaaaata aaaaccatat
     4921 ttgggatgaa tgggcatttg aacgctacat caaaagtcca gactataatg gaccagatat
     4981 gactgatttt ggccatagat gtttgacaga tcctgaattc aatgaagaat ataaaaagca
     5041 gagcaagctt ttttgcgaga agatcctaac cgatgattcc tttgctgaaa catacggcga
     5101 tcttggacac atctacggct atcaatggcg tcactgggaa acaaaagacg gtggctttat
     5161 cgatcaaatc aaacaagtga tcgaagcaat caaaaagact cctgattcta gaagattgat
     5221 cgtttctgca tggaatccgg aagatgttcc tagcatggct ttgcctcctt gtcatacgat
     5281 gtttcaattt tatgttcaag agggacggct aagctgccaa ttgtatcaac gcagtgggga
     5341 tgtgtttcta ggcgttccgt tcaacattgc aagttatgcg ttgctgactc acctaattgc
     5401 acatgaaaca ggtttagcgg ttggcgaatt tgttcacaca ttaggagatg ctcatcttta
     5461 tatcaatcat atcgaacaaa tgaaagaaca attgagccga gaaatacgcg catttccgac
     5521 tttagttttg aatcaggaaa agcagtcagt atttgatttt gagatggaag atatccaatt
     5581 agaaggatat gacccacatc cggcgatcaa agctcctatc gctgtttaga atcagaaagg
     5641 atgagaaaat gttagctgca atttgggcac aggatgaaaa cggattgatt ggaaaagaag
     5701 accgtcttcc ttggcgtttg ccaaatgatc tgaaattctt caaacaaatg acagaagcaa
     5761 atacactagt gatgggacga aaaacattcg aagggatggg tagccgtccg ttgccgaatc
     5821 gtcagacgat tgttttgacg agagattctt cctataaagc agaaggcgtg catgtcatgc
     5881 atagtgtgga agacgtgctt gctctggaaa aagaaacaga cggtatcttt ttcatcgctg
     5941 gagggtcagc tgtttatcaa gaatttctgc cattttgtac gatattatac cgtacagtca
     6001 tccatcatgt attcgatgga gatgcttatt ttccacctgt tgactggtct gattggtcac
     6061 tgatcaatac tagtcaagga gaaatggatg aaaaaaatcg ttatccgcat caatttgaaa
     6121 cgtatcagcg taatgagaat cctgtaaaaa gcgggacagg cgaattgacg atataaaaaa
     6181 gctatggata gactagctgt tatttagagc tgtcccatcc atagctttat tttttttatt
     6241 aagtaaagaa taaaacagag aagtacataa aacctgcacc taacataaca aacaaatgcc
     6301 aaacaacatg catatagcgg atagaattca agctataaaa gaatgcgcct atcgtgtaag
     6361 aaagcccgcc tgctaccatc aaaataacac cagtcattcc aagagagtga taaagaggaa
     6421 cagcagccac gacacagagc caccccataa aaatatagat gatcgtagat acttttgata
     6481 ctctctcccg tttatgcaac gtcaacgctt tatatataat gccaagaatc gcaaacaacc
     6541 agattaatac aaataaagtc caacctagcc atcctcggat actcagcaaa caaaaaggag
     6601 tataacttcc tgcaatcaaa agaaaaatcg aactatgatc gaatacttgg aacacctttt
     6661 ttgcttttgt aaaaatcaat gaatgaaaca aagtagacgt taaaaataaa agaatcatca
     6721 tcgatccata gatagcataa gagacaatat ggagggagga atgcaagtgg gcacctttta
     6781 ctaaaagaac cactagtccc gcgatactca atccagtccc aattccatgg gtgactgcat
     6841 taaacacttc atttaatatt tcatacgttc gattaaattt cgttttttcc atgaaaacgg
     6901 ctcctttact aggtgtaatt aatgaaaaat cattatttgt ctgttatact aaaaatagaa
     6961 attgtcttac atgtagttta acatgaataa ggcatcttgt taaagaaaga gagagagaaa
     7021 ataatgacaa atgtaaaaat cgtaacagat tcttcatgta cgatggaaaa aaatgtacgc
     7081 gatgctttag gcattcgtgt catgccgcta tccatcatga tcgacggaac agtatatccc
     7141 gatgatgacc aactagacgg cgaaagattt atggaaatga tggcgaaagc aaaaaatctg
     7201 cccaaaacaa gccaaccacc aattggagaa ttcatctcga tgtatgatga gctaggagaa
     7261 gacggcagtg aagtgatttc gatccatatg acaaaaggct tgagtggaac agtagaagca
     7321 gcaagacaag ccagtaatct aacaaaaacg aaagtaacgg ttatcgacag tgataccact
     7381 gaccaaggat tatcttttca ggtaattcga gcagctgaat tagcaaaaga aggtaaaaca
     7441 gtagagaaaa tccttgaaga agtcaaaaaa gtacaagaca atacaaaatt atacatcgga
     7501 atatccacac tagataactt ggtaaaaggt ggaagaatca gccgaacaac tggtttgctg
     7561 tctagtgttt tgaacatacg cgtggtgatg aatttcgccc attctgaatt aatccctgta
     7621 actaaggggc gaggaaagaa aacgttcgat aaatggttta ataatttgaa aaatgaactg
     7681 aaagaattgc caaatgtgcg acaaatcggt atttcacatg cggatgcaaa agaattggcg
     7741 caagaattca aagagggttt gcaagaatta ttcccggaca tgcatatccc tgtactgcat
     7801 acgaatccgg ttatcgctac gcatactggt aaagacgcgt ttgcaatcat gtattatgta
     7861 gattagtcga aaagaggata agccctcagc ctgaaaggct tgcagcttat tctctttttc
     7921 tttataaaat taggaaaata attgttttct tttttcataa agactacctt tttgataaaa
     7981 tttttgataa cattagaacc aatcgaatac aagaggtgaa aaaatgaaat taacgaaacg
     8041 acatttgatc ctcgttttgt tcccattatt aattgcgatc atcatctatg caggtttagc
     8101 tgcttctata ccgaaagctg gcccactaat gaaaccagta actactgtga gagaagatcc
     8161 aaataaaaaa gaaaaacttc actacatagc tatcggagat tcgctgactg aaggagtagg
     8221 agatcaaacc aagcaaggag gattcgttcc ccttgtcgca aatgatctaa aagaccgtta
     8281 taatttgacc gcggttgaaa cagaaaacta tggtgtaaat ggtgaacgaa gtgaccagat
     8341 cttaaagcga gtaaaaacaa aagaagaaat tcgaaacaat atcaaaacag ctgattttat
     8401 cacactgact gttggcggta atgatttgat gaaagttatc caaaataatt tattcgggtt
     8461 aacggtcaat tcctttaaaa agccactgaa aaactatcag gaaaatgtca cagaactatt
     8521 ggaagaattt cgatccctca ataaaaccgc acctatttac attttaggca tctacaatcc
     8581 attttatttg aactttcctg agatcactga catgcagaca attgttaaca attggaacaa
     8641 aggaacagaa acggtgacaa aaaaaatgcc gaactgctac tttatcccaa tcaatgattt
     8701 gctttatcaa ggattgaatc aggaagtagg tgtcacagaa gaaggaacag atcaaacaac
     8761 tagcacgaca gaaaatctaa atggcatcaa aaataatgtg ctctatgaag aagatcattt
     8821 ccatccaaat aatttaggtt atcaattgat ggcaaatgca gtgagagatc agctgatcga
     8881 gacacaaaac caatggttag agaaggagga tgatcaataa acatgaaaac aagatctgac
     8941 gtatcttcaa acaaaacaaa gaaaacaaat tactggaaat tcgccttcct tatccttctt
     9001 ggggtagtac ttggttcgac cgtattttta ggcagccgta tttttgctaa tcgggaacca
     9061 gaactcccag aaataccagc tcttacggaa agacaaggag atcctgtctt aacgatcaat
     9121 tcaaataaag aaaaagtcaa tcaaatcatc agctttttcc ttagtgagta tcaaaaagat
     9181 agtgatattg aatataaatt ttatttggaa aatgaagcac tactcaatgg tactttcgaa
     9241 gtactaggtt ttcctatcga tttctattta tattttgatc cgtatgtgat ggaaaacgga
     9301 aatgtccaac taaaagctag aagtctttct atcggaacat tgagtttgcc aatcaaagat
     9361 gtgatgaata tgatcaagag aaactataaa ttaccagatt ggatcgaagt caatacagat
     9421 gatctgacta tcatgcttag gttggatcaa ttccgaatgc aaaacgggat gtatattaaa
     9481 gcagataaaa tcgacttagt aaatgatgac attcggttta gtctatattt gccaaaagat
     9541 acctctgatg cttcaaacaa ctcaaatacc aacaaaacta gcaccagcag tactgaaagc
     9601 aagacaaaag aaaataaaaa atcatcggat gagtagtatt agagggggaa tcataatgga
     9661 acgagcaata tttgcaggag gctgcttctg gtgtatgatc cagcctttcg acacgcttcc
     9721 tggtatccat acagtgatgt caggatatac tggagggcat gtaccagatc cgacttatga
     9781 acaagtaaaa agccaaacga ctggacatac agaagcagtg gagattatct atgatccaac
     9841 attgatttca tatgaacaat tagtagaact ttactggcag caaactgatc caactgacgc
     9901 tttcggacaa ttcgaggatc gcggtgacaa ttatcgcccg gtgatctttt atttgacaga
     9961 agaacagcgg atcattgctg aaaaaagtaa gaaacagtta gctgaaagtg gacgtttcga
    10021 acagccaatc gttacaaaaa tcgaaccagc ccaaccattt tatctagcag aagaagacca
    10081 tcaagagtat tataaaaagc atcctgaaaa ttttaaaaga aaccatgcac gccgggctgc
    10141 ctttatcgaa gaaaattgga ggaacgaagg gtgaatcgaa gcttttttca ttatttaatg
    10201 acactgcgag gcggtggcac acatgatgct ttatctgttt tcgctacaga agccggtaaa
    10261 gacatccaat ttcctaagca cagctctagc tacgaagaaa tttctaatta tctggaactg
    10321 aatgtcgact atttgccgtc catggatatc tttgacgaag catgggaaaa atatttagaa
    10381 aataatcatg acatataaga gatagttttg tactttatga tcaaaaaagt tttttgtcca
    10441 atagcctaat tgaaagaatt atttttattt cagctatcta gtcgcatttt tttgatattt
    10501 ttcttataat aaagaaagaa tgaaaaaaag agggatggat tgatagagat tgacaaaaaa
    10561 acaacgctat attaatcgct tctggcttgt attcaaatac ttacttgttt ctgtattcct
    10621 tgcgttcatg ttgcggggat ttttattcat cccggtacca gtggaaggca attcaatgga
    10681 aaacgtgttg aagcaaggtg atatggttgt gatggaaaaa ttttcggaga tcagacgatt
    10741 tgatattgtt gtttttcaat tagcagatgg cacgatttat atcaaacgag taatcggtct
    10801 tccaggagaa aatgtcagct accaaaatga tcaattgaag atcaatggga aagtagttaa
    10861 ggaaccttat ctaactaaaa acctgaaatc agatcatgca aatgcatcct atacgacgga
    10921 ctttacacta caagagctaa cgggacaatc caagcttccg gaagataatt attttgtact
    10981 tggagataat cgaagagttt caaaagatag tcgttcgttt ggcacgatca ataaaactga
    11041 tattctaggt aaagcaagat ttgtctatta tccacttgat gaaataaaat ggatccagtg
    11101 agaaaca
//
LOCUS       DAFEIE010000080        10157 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFEIE010000080
VERSION     DAFEIE010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.083"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(561..1601)
                     /locus_tag="LP345_002439"
     CDS             complement(561..1601)
                     /locus_tag="LP345_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1761199.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1950..2276)
                     /locus_tag="LP345_002440"
     CDS             complement(1950..2276)
                     /locus_tag="LP345_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761200.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2263..3066)
                     /locus_tag="LP345_002441"
     CDS             complement(2263..3066)
                     /locus_tag="LP345_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1761201.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3419..3709)
                     /locus_tag="LP345_002442"
     CDS             complement(3419..3709)
                     /locus_tag="LP345_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBL1761202.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3845..4024)
                     /locus_tag="LP345_002443"
     CDS             complement(3845..4024)
                     /locus_tag="LP345_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761203.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4021..4371)
                     /locus_tag="LP345_002444"
     CDS             complement(4021..4371)
                     /locus_tag="LP345_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761204.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4364..5689)
                     /locus_tag="LP345_002445"
     CDS             complement(4364..5689)
                     /locus_tag="LP345_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL1761205.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6139..6753
                     /locus_tag="LP345_002446"
     CDS             6139..6753
                     /locus_tag="LP345_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1761206.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6918..7922)
                     /locus_tag="LP345_002447"
     CDS             complement(6918..7922)
                     /locus_tag="LP345_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761207.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLE
                     LKTLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITA
                     CEIGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEK
                     RNKLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNK
                     SQITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD
                     "
     gene            complement(8381..8638)
                     /locus_tag="LP345_002448"
     CDS             complement(8381..8638)
                     /locus_tag="LP345_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL1761208.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(8631..8900)
                     /locus_tag="LP345_002449"
     CDS             complement(8631..8900)
                     /locus_tag="LP345_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1761209.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(9031..9210)
                     /locus_tag="LP345_002450"
     CDS             complement(9031..9210)
                     /locus_tag="LP345_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761210.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(9591..>10157)
                     /locus_tag="LP345_002451"
     CDS             complement(9591..>10157)
                     /locus_tag="LP345_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761211.1"
                     /translation="EEQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETE
                     KYIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATID
                     DYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTY
                     TYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3101 a         1855 c         1458 g         3743 t
ORIGIN      
        1 tccgttgcgg gtaataccgt aacactgaag ggcacgcatt aaggcgtcat cttaatgctt
       61 tcctgtagga cactgacgga gattaccagt ctcccgagcc ttacaggggc ctttcttttt
      121 tttgtatttt caattatcac aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc
      181 acaagcatat cagacaatta aatttaaaac aactaaaaat atacaaaaaa gtgtaattga
      241 atattagcag cactgcctga aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt
      301 gaattacctc tcttcatgaa ttattataac tcaaaaaagc acatatgcaa acactagttc
      361 cctatttttt tgaatgaaaa ataactaaaa tatctaacga ttatgacttt aaaacctacg
      421 tttgtgattg ttttcataaa cttttaatct aaaaactccg gaataatagc tatttatttg
      481 taacatttgt aataaaatta aaatcataaa aaagttctaa tttaaaattg atcattttta
      541 tagtgatcgc tttttatcaa ctactctagc caattttccg tactaactgt tggtaattcg
      601 ttaaatgttt ctctttgttc gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa
      661 ttttttacat aaacgaaaat tagattctgc aaattgttta ctttttcagt tttttgtttt
      721 tgataagctt tcagcaaagt catatataat cctttgtcag catcaattcc ataagattcc
      781 agttcttcat aaacaacaac tgtttgctct aattcttcag cttttttctt tgcattatga
      841 atagtttgga cggttttttg agcgtcttcg taagtactag aaaatgtttt tatcaagttt
      901 aatacatttt ctggtacaaa tgtatttata ctgtcctctt tcatgatgtc gacgaagtta
      961 tctagtaaaa cttgattttg taactgatca gtttcagtgt ctattatgtg tctattagtg
     1021 tctatagaat tagaatagaa tagattgtct gcgattttcg caattacggt tgagtccttg
     1081 atatgactgg attttgccgt atttgcgatt ttcgcaatta cggtggtatc attgatttct
     1141 cgcggttttg ccgtatttgc gattttcgca attacggtgg tatcagtatt gtcttcctct
     1201 tccatgattt taaagacgtc ttgattcgtt acttctggct tgcctaagta caataaatta
     1261 ggcatggatt caatcttacc gtcacgttta tttactcttc ctctcttctg tttcagaaga
     1321 cctgcttttt ctaattcctt tttgatttta gatactttac cttcgcggca ttgtaacaat
     1381 ttcattaatt cttcaactgt gaatatgaaa aatatattat catcagaatc tacccagtta
     1441 tttttgactg aataatcaaa tcgatcttta agtagcatat aagcaatttt tgcatcattt
     1501 gatagatcca tgtatttttc gttagtaaaa aataccttag gcatttgata atatttttca
     1561 cgataaattt cttttgattt gtaataatta aaatcattca tagccaatcc tctttctgta
     1621 ggatagcgtt ttgttcaaaa ctatgttaca atgaattaaa caaatatatc tatccactat
     1681 atatttttct actgctgata agtcgccaaa ctttgttaaa gcagtagtct ttttttatct
     1741 ttttttagtt taccttaaaa aataaattaa agcaaaccgc tctatttcaa ggtttaagct
     1801 catagtaact atatcacgat attacaataa tattatatca cgatatcgta atattacaat
     1861 atgaagataa gcgacttatc agctttgata ctactgattt ttataaaaaa aatatcacga
     1921 tattatgata tcgtgatatt gaatgtaaat taaattttat tttgtttctt tgctagttta
     1981 tatccttcaa tcaagtattc ttcaggtatg gactttaata gcgcatcttc tataacgtct
     2041 ggtttacttt tgtctgattc agcaatagtc gtccaatatt tgagtgctga cattagaatt
     2101 ggatttatac gaatgctatc tgctgttctt acactacttc cttgatcttt tatgacttta
     2161 cttatatttt tcttggttaa ttcgatttct tctacttctt ttgatttaaa attcttttta
     2221 tttttatttc ctagtaatct acttactgca gcttgactgc gattatcttc tgccatcaaa
     2281 atcaccaact tcttttaaat attcttctgt aaatgcttta tagtcatctt cagctgttga
     2341 gggtttatta aaattgatta gatctgatcc agcagcttgc gcttcgtcaa cggttattgt
     2401 cctacgaata taagttttga aaatttttgc accaatgact ctagaaattt cggttgctgc
     2461 agacgtcatt tctttagaaa tgttataacg cttattatac ttagtaaata gaactcctcg
     2521 tacttcaagc ttgtcgttcg tatattcttt taccgtttca atagtttcac ttaactttat
     2581 tagtcctttt aatgagaaat acgcagcttc aactggaatg ataatttcat cagaaacagt
     2641 aaatgcgttg actgtaagca ttcctaaact tggtggacaa tcaattataa tataatcata
     2701 gttgtccttg attggttgaa gtactctttt aagcctgtgt tcacttccta cttgagtaaa
     2761 ttccctctct gcagaagaaa gggctatgtc ggctggcaaa acatcaattc ctttatagtc
     2821 cagaatagca tctgtaatgt cagcctcccc ttttaatact tcataaattg taggttggtt
     2881 tgttccatct atatcgaaac ctacattatc tgtagcattt ccctgaggat caatgtccac
     2941 taaaagtaca tttttaccgt aaacaaattt caaacatgct gctaaattaa cgctagtcgt
     3001 agttttagaa actccacctt tttgattggc tactgacaat attcttgcca ttaaaatatc
     3061 ccccattcat cttatattat aatataatta tatcataata ttgtgatatt gcaatatcgt
     3121 atatgcatta tattgtaata ttgtgtgatt attttgtttt aaagatatat atcggttcgg
     3181 atataaagat tattcatatg ttattcgaaa ttaaaataat cactttttat tactttaaaa
     3241 ttttttatta atgataagaa atatgttttg cgagcagcaa ctagaataat ttaaacatta
     3301 ctaaactgtc tatattgtta ctaataattc ccttcttata gtgcattttc ttagaaaaaa
     3361 acaatattac gatatcatga tattaagata tcgtaatatt atacaattgt gattgatatt
     3421 atatatgttt ttttattttt ttatcatgtt taatcttgaa ggaatcatat tctttttcta
     3481 aagacaggag cttttcataa acatcagaca tgtttaaact agaggccagg cttaaatcat
     3541 aaacgaatga agcaggtaat gattttattc tacgttgtcg ggttatccag cttgcaaccg
     3601 ttccttgtgg gtaggcatat aactcacaaa attgttctac agtgattcct aaattcttga
     3661 taatgtaaac attgatcggg tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc
     3721 ctactttctt ttattattgc gtttgcaata atagtttaac acacgcatta ttctagtatc
     3781 tactcctatt tgtaaaaaca aaaaaggatt catagagata actctataga atccgtaaaa
     3841 taccttatat atataacggg aagatataaa acctaaaatt atgataacct gctgcagctt
     3901 ctacatagaa agagaagcgc tcaacaccaa cctcatttat caaacgttgg ccataacccc
     3961 aaatctcttc tgatagctga tcaaaggtta tatactttag ctcatattgc tggataatgt
     4021 tcattctaat cgactccatt tattatcctg gtaaaattcg atatgacgta tttcgtcgta
     4081 gtgaattttg tcttttccaa cgtagatccc cagctcatca ctacctaaga tcttgccaat
     4141 gatatcttct ggatagtatc cttcagcgtt tcgttcttct ttttgaatag atactgatct
     4201 attttttatg actgcagcgt tcaatacttc cgcaatctct tcagtcgtca tttgttcttt
     4261 tgctaaattt tgactggttc gttgttcatt gtcggcatca atttcttcag tatgatcaga
     4321 taaataaaac cctgcccact ttaaacgtcc acgatcattg taatcaatca tttttaattc
     4381 ccccatttcc gcccgcatga ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt
     4441 ctaacattga agaagcatgt acaatcgacg taaaaccata tttttgccga atcttgtcaa
     4501 taattttatc taaattttct tcgtcaattt gcttttgtgg atcactaaat aaatccagct
     4561 gaagcgaatc ggtgtacaca agcttgctat aggttattcc aacatgcctt acttcttgtc
     4621 cttcataata cttatcaaac aagaaaagac aataattctg caattccttt gtattatctg
     4681 tgatagggat cttcatctgg tgtgaaaacc ctggtctcgt ttctaagatc gacgtgccaa
     4741 tgtgtaaatg gacacaacct gttttacagt tatgctgcct aatgcgtatc gctacttgtt
     4801 ccgccatttc ttttaccacc agctcgattt catttcttct agtataatct cgtggtaaca
     4861 cttgtgaatt tccatatgat ttttcctttg tcggttctgg tgggattgct atatctgttc
     4921 gatcgatccc attagcatgg aagtacagct gtaagccaat cacacctagt ctattcttaa
     4981 tcgtataagg attccagtta gcaagatctc taatgctcat aatccccatc tgattgagtc
     5041 tttttttcat tcgagagcca attccccaaa agtccgtcat ttcaggaata ttccatactt
     5101 tttcaggaac gttttcgtac gtccattccg caacaaatcc ttcattatgc tttgcttcgt
     5161 tgtctaaggc tagtttagcc aaaaggggat tatctccgac acctactgta gcaatcaatc
     5221 ctagctcttc tttaatattc tcctggatca tttgagccag cttctttctc cgttgacttc
     5281 gtgttccttc agtcgtaaaa agattcagtg atcgggtcac ttttaagatt gattcatcga
     5341 tcgagtaaat cagtagatct tcatcagcca catatcttct gaaaatatta tttacctgca
     5401 tatttcgctt gatatatagg ttcatacgtg gtggaacaac gtgtagtgtt ttaggaaatg
     5461 gttgtggtaa gtcacgtggt ctactcacat ttgtaatacc ataccgcttt tttgcttcag
     5521 gagaagaagc taatatcaat cctgaaccag tattatcagc tcgactcata acaacaagtt
     5581 ctgttgttaa tggatctaaa tttctttcta tacattcgac acttgcgtaa aagcttttca
     5641 tatcgattaa aaagtaatca tttactggct cttttgaata atccatcata aataacactc
     5701 cattctttca cattatacaa acatatgttc gatattgtaa agaagaaata gctaaataca
     5761 taaaaaaaga agcataggta tgctatcacc ctgcttcttc ttttgatttg tatgatcaat
     5821 ttattctatc actttactaa ttaatttgaa aatctaataa aaactctcac tctaaaagag
     5881 tgagagactg caaattagag tacggacttt tttggagttc cgttctttaa tattaacaaa
     5941 tgaataaaat ccttacaaca tttgagaata agttatcagt agacacttac aaaaaattct
     6001 catactattt cctccatcat tagtttttgt ctatataagg tttaccctaa atagacactg
     6061 gtataacatt gaaaaatatg gcttcctcgt gtatgattag ggtgtatttt aaatagttgc
     6121 agaaagtagg taaaagtttt gagagttgca tacatacgtg tctcatcgat cgatcaaaat
     6181 gaacaacgcc agattgaaga aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa
     6241 caatctggcg caacgattac tcatcgacct gttttccaag aagcattaga ttacgtccga
     6301 gatcaagata tttttattgt ggaagctatt gatcgacttg gaagaaatta tgacgagatc
     6361 atcgcttcag tcaattactt gaagaagaaa aatgtgaagc tgatcattac tagtttaccg
     6421 atcatggctg aagcaattgg caatcctctc ctggataaat tcattaagga tctgatcatc
     6481 caaattttgg ccatgatcgc tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa
     6541 ggaattaaga tcgcaaaagc aaacggcgtc tacaaagggc ggcccaaatt atacagtgca
     6601 gacgcaaaag atccccaacg tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat
     6661 ggtgttgcga ttgctaagat tgctaaagac tacaatgtta cgagacaaac cgtgtataga
     6721 ataaaaaaag acagcatggt caatgacaaa tagttgatca tgctgctttt attatcttct
     6781 catctttaat ttcctacata taattactat ctataaaatt aagtcttact cagaacagat
     6841 aaagcataaa attccaacaa accatttttt acttaactaa ataaagagtc tgttaatata
     6901 atcttcactt atttacgtta atcccctact gtatttgttg gttccttatc tatattttct
     6961 acaaaatcct tattatcttg tgatttagct tcgtataatt ctttgtatgt cgacacattg
     7021 gttatactaa ttcctatagc tagttcttga gactctactt ttctctctag ctcctttgac
     7081 aaagtgattt gagatttatt tggttccgtt ggagtcaatt ctatagattc ttcataaaaa
     7141 tctctataca taaagctatc attaatttta taaaaaaaat taaatgtttt tagcactgcc
     7201 atataacatt caaaacattc ttctatagtt ggtttacttc cttgaggaga atgaaccaat
     7261 ttattacgtt tttctatgaa atttttaatt tcctttctta tttctttcgg aaactcaata
     7321 ttaaagtacc ctttaaacat gctccctaat aatttgtcta cagggggaga ttgtaaattc
     7381 tcaaatatta gagttaaatc aggtttctct tgttgataaa attcctttac ccctatttca
     7441 caggctgtaa ttatcgaaat aaacctatct ctagtatttg atatattttt acttctttta
     7501 aggagtataa gagaaaaggg gatactttcg tgtccatgca tgtaattaac taattgttga
     7561 gcttcagaag ttatatctct aattatatag ttaacggaat taggaagtgt ctttaactct
     7621 aatgaaattt ctatccaatt actatcttct aatctgtata tgctcgaagt ataatttgat
     7681 tcgtcagcaa gcatcgctac atcccaaaca ctgatcataa aatcttttaa acgttcaatc
     7741 atttcagcaa tattgctaaa atcagctaat ttttctttag aataaaaaaa aacatttata
     7801 tcagaatcaa taaattctat tttttttatt actatatcgt catcattatc ttgaccattt
     7861 atgtttattg ttccctgagt ggggagtact tctttcaaat tcaagttaaa tttatattcc
     7921 attacttctc ctccaatata taaaaattac ttaactgtat ccaaatttaa tatgtaaata
     7981 aatcattaat ttttagctaa attctatgag aagtttattt ttgttgtttt tgctaattaa
     8041 ctaaaactag tacaaaaaat ttaaaataga ttattaaacc tattgcttat tctattcagt
     8101 catatatata agcgtcatcc tttagtaact aacatcccac actacaatag tattataaca
     8161 tatctattca acttcaaatt gttgaaattt aagccattta tatttacttt tcctcaactt
     8221 tagaaatgat tttactaacc ttatatccgt aatacgcgta acaaacacat tcattaataa
     8281 caatcaacac taagctatat tagcttttta aatgactagg gtaaataaaa taaggatcaa
     8341 aaacttttaa gtttctgacc ctttccttac ttccgattgg ttaatagtga tcttttgcag
     8401 aataaataaa tatcgtttca ttttcaactc tatatatcag tctatgttca tctgtaattc
     8461 ttctggacca ttttccagat aaatcatgct ttaatggctc aggttttcct aatccagcaa
     8521 agggggaacg atcgatatct tttattaact tgttaatctt ttttatattg cttttgtttc
     8581 cttgctcatg ccaataaaga taatcatccc aagcatcatc agaccaagcc ttaatcatca
     8641 gattcaacct cgattaagtc atgtgtttta aatgcacctt tggagaattg ttcatctcct
     8701 cgacgaattt tttccatgac gtaattatta gaaagtgttc tcaacgtttc ttgcatagaa
     8761 tcataatctc tttttgataa tacaacaact gtatcttcta catctttact tgttacaata
     8821 agtgtttcag catcctcatt aacttgtttc atataactac gtaaattttg gcggaaattt
     8881 gaataagcta ctgcttccat tcctttcacc ccttatttat ttctataaaa caattgtaca
     8941 ttatattgta caattaagca aatgattaat attctaactt cttataatta aaagtgctat
     9001 cacttttagt ttttaggata aaaagtgacg tcactttttg agtgctggta cctcaaatcc
     9061 tgctttttct tgggcaatca ataaatctaa cgcaatacac ataatcctgg attcactttt
     9121 gccgtacttc tgctttagtt gctgcaattc tttttgtctc ttttcatcca acgtaacggg
     9181 taaccgttta tttcctattg caattggcat tagtactctc tcctttcatc gaaataaccc
     9241 tatgaaaaat atggctgcaa tcatcttgaa tagtagactc acaagggcta atacaaagcg
     9301 ccaaaagatc aaacaaaata ccagtattgc caaaaatact acgaagttta aatgcacagc
     9361 tgcagcatgg cgcataagta tttcgccaac aaataggact aacaatagag gaatgatttt
     9421 attcatatgg atctccttct ttctcttagg ttatcgggtg ttgcccgctt atttcgcacc
     9481 acctaagcgg cgggggcggt tggagcgatt ggtgcgaaat aagaaccatt cccttagtta
     9541 ctaggttttt tgtccttatt tcacacattc tcacttttcg gtataaatga ttattgcctt
     9601 tttttccttt caaatcgttg atatggcatt cgtttacggt caagttcatt ttggatttct
     9661 tctgtatcgt cgtaagtata ggtgtctaaa aaatcagtta aagtcgtgta ccagtcgtcg
     9721 cctgggttat ctacttcttc tacatattcc ctcaaaaatg cttcgggtac agcgagttca
     9781 taatccattc ccattaacac gatagattcc gttccacacg tcaaaaatct agtaaataca
     9841 aggtaataat cgtctatcgt cgcatctttg ctgtttagct cttccatttc ttcttccatt
     9901 aattccatgc tctcaaaaat tgaataatat tctgattctg agtaatagtg tttcctgcaa
     9961 atcgtgtagc tgacaaagtt ttcgaccagc tcactccttt ctaggtaaac attcatgatg
    10021 tatttttctg tttctagtcg tagaagctcc gttccttttt ttaccgtttc aggacgacgt
    10081 ttatacacgt ctaaacgatt atggctgact gtgaccttcg tttgactcgt ttcactttcc
    10141 aaatacaatt gttcttc
//
LOCUS       DAFEIE010000081         9494 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFEIE010000081
VERSION     DAFEIE010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.084"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            50..1357
                     /locus_tag="LP345_002452"
     CDS             50..1357
                     /locus_tag="LP345_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBL1761212.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            1476..2675
                     /locus_tag="LP345_002453"
     CDS             1476..2675
                     /locus_tag="LP345_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL1761213.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(2702..3970)
                     /locus_tag="LP345_002454"
     CDS             complement(2702..3970)
                     /locus_tag="LP345_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBL1761214.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(4133..4779)
                     /locus_tag="LP345_002455"
                     /pseudo
     CDS             complement(4133..4779)
                     /locus_tag="LP345_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(5187..5690)
                     /locus_tag="LP345_002456"
     CDS             complement(5187..5690)
                     /locus_tag="LP345_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1761215.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSPSMRKRWQRY
                     FGKESSI"
     gene            complement(5813..6577)
                     /locus_tag="LP345_002457"
     CDS             complement(5813..6577)
                     /locus_tag="LP345_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBL1761216.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            6685..6960
                     /locus_tag="LP345_002458"
     CDS             6685..6960
                     /locus_tag="LP345_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBL1761217.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            7398..8348
                     /gene="yidC"
                     /locus_tag="LP345_002459"
     CDS             7398..8348
                     /gene="yidC"
                     /locus_tag="LP345_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL1761218.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     IDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(8527..8727)
                     /locus_tag="LP345_002460"
     CDS             complement(8527..8727)
                     /locus_tag="LP345_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761219.1"
                     /translation="MGGISALSFMENGVLCGRATWAKGVAPFVTEGEEKASSWMLEEG
                     KQNIKELSTLLEETATPVYVDR"
BASE COUNT         2872 a         1981 c         1714 g         2927 t
ORIGIN      
        1 ataaaatttt aatttgtagc gaaacaaatt aattacaagg agatcggata tgtccataaa
       61 aaaaacacgt ctagtcctat tattggctag tctcattctt tgccttgctt cttttctacc
      121 agctgttgct gtgcaagctg aagatacgtt caaagtaaat gcaaaagcag cttttgctgt
      181 agatgcgcaa agcggtaaga ttctttatga tcaagatgga gaaaaaacca tggggatcgc
      241 ttcaatcaca aaaatcatcg gtctttacat cgtccttgat caagtaaaag aaggaaaact
      301 gtcatggggt gataaagttt cgatttcaga ttatgcagaa aatttgagta tcaccccaga
      361 tttatcgaat gttcctttgc ataaagaaaa cacctacact gtcaaagaat tattcgactc
      421 tgcaatcatc cagtcagcca atgcttcaat ggtggccttg gcagaaaaaa tctctggcag
      481 cgaagctaaa ttcactgaac gaatgaaaga acaattgaaa gattggggaa tcaaagatgc
      541 aacaatcgtt aatgcatcag gattgaacaa ctcttatctt ggcgaaaacc gaccagaagg
      601 cactggagaa aacgacgaaa atcaaatgtc tgctcaagat gtggccatcg ttgcccgcca
      661 tttgatcttg gatttcccag aaatactgga tgtatcaagt actacgaccc aaatgtttgg
      721 cgaaaatacg caatcaccag tggaaatggt caactggaac tggatgctcc caggattcgt
      781 taattacaag gaaggcgtgg acggattaaa aactggtacg actgagcttg caggtgcttg
      841 tttcgttggt acgatcacta aaaacgatca acggatcatc actgtcgtat tgaatgcgga
      901 cggccatgcg gaaaacccga gtgcccgctt caatgaaaca gaccgtttga tggactactg
      961 ctatgacaat tggtcagaaa aagagctcgg aaaagctaac gcaagtattc ctagtctaaa
     1021 aaccattgat gtaaaagacg gaaaagaatc aacagttcct gttgtgctta aaagccctgt
     1081 aaaagtatgg gtacgaaacg atatggatac tggcaaatta acgatcacgc caacacttga
     1141 caagaagcaa gtcactgaca atgagatcca agcacctatg gataaaggta caaaaatcgg
     1201 taccgctacg atcaccttgg cagacgataa attaggctat ttagaagaca acaatgcacc
     1261 atcaacagag atcattacgg ataaaacagt ggaaaaagcg aatatattcg tgattggctg
     1321 gcgacgcgtc gcagaatttt tcggcaactt gttttaattg aacaataaga aaaacatctt
     1381 tccatcggaa agatgttttt ttgctttttc tagtttaaat aacagctttt ttcatctatt
     1441 ttcgttatac tgtataagaa aaaggagttg aatttatgaa tctaaccaga gatctgatct
     1501 ttttagttct ctatcttatt ggggtattct ctatcgttta ttggcgaaaa cagaagaagg
     1561 atccttcctt gttcttttac ggcagtacgt ggacatttac ggtaatctta acttattttg
     1621 tcgtgttgga aattttttat tcgacctttt attttttgat tccattgttg ttctttagta
     1681 tctttgcttt ttcttatttc acagaaaaac gaaggctact gaatggtctt ttattcaatg
     1741 ttttactcat cagtttcggc atctacttgt ttgtcttgct gtatgaaacg caaaatattt
     1801 ttcttggcgg actgatcgcc ttgatcacga ttccattgct acttgtcctt ttatttggta
     1861 tttatggatt gattgttttt cttttttgga acggggtcac agttttacgt agagaatccc
     1921 attcattagc taatctttta acgttgatac tagccatttt tcttacactg tttcttgttt
     1981 ttgacttttt cttgttaaaa tatttgccgc aatggataaa tgctttgttt ttctgcgttc
     2041 ccctgatctt gatctatcta tttatcgtat tctacaactt tttgactgtc tcattcttgt
     2101 atcagttcaa ccggcctcga tacaatcaag acttcatcgt tgtgttaggc gctggattga
     2161 tcaatggaga aacagtttct cctcttctag ccaagcgaat caataaggca attgcttttt
     2221 atcgggctca aagccgtgct acattaaatc cgcccatctt attgatgtct ggcgggcaag
     2281 gagcagacga aaaagtacca gaggccattg cgatgaaaca atatgccatg gaacaaggaa
     2341 tccctgaaag agacattctt gtcgaaacca attcgacaac cactttggaa aacatgctct
     2401 attcaaagga aatcatggat cagcaaatga aagggccata ccgcgcgatc tttagttcca
     2461 acaattacca catttttaga gccggtcttt atgcgcggca agccaaattg aaagcaaatg
     2521 gtattggtgc aaaaacagct ttctactact tgcctaatgc gtttttaaga gaatacctcg
     2581 ccatcttgat gatgaacaaa aaaagacata tgatcatttg cggattgctt ttcgcaggct
     2641 ccgcattctt atcgctgatt actttacttt tctaaaaaaa caaggtgtga caaaacatat
     2701 gtcacacctt gtttttttct ttcattctct taactattgg caaaaagagt atcccttttt
     2761 tgaccgctac ttgctgagca gaataaatac cgctgttgcc tgaacacata aagctgatca
     2821 agcagatcat aaagaagtat actgccgctt gtgaaccgaa caattcgatc cccatcacaa
     2881 agcaggcaat cggtgtattt gtcgcaccag aaaatactcc gataaagccc aatcctgcaa
     2941 gaaaaggaac agaaacatgg agcaaaggcg ctagtgctgc accaagcgtt gcaccaattt
     3001 caaacaatgg tgtcacttct cccccttgat atcccgcgcc taaagacaaa actgtgaaga
     3061 ataacttccc aataaaatca tagacatgtg cctgtccatt aaatgattct tgaagtaacg
     3121 gaagactcaa tccgagataa cgttgtgttt gcaaaatcaa tgctgctgcc acaactacag
     3181 ctccacctat cgtatttcga caaacaggat gaggaatcca ttgtgcatat cgcgctttta
     3241 aaaagacgat cgaacggctg aatacccaac caatcaaacc aaaagcaatc ccagcaacaa
     3301 aaactttgaa gaacagcaac atactccatt caggaatcac acccatttgg taatgtagat
     3361 gagaaacacc atagctttct gtcatgaaat ttgcaaacag tgcagcaaag aagctaggga
     3421 agatcgcttc tgttcggact ttcccgattg ccaacacttc taatccaaat aatgttccag
     3481 ctaaaggtgt gccaaataca gaactaaaac ccgcactgat tccactgata atcaagattt
     3541 cccgttctga tttatccaat cggaacaaac gtgccgtatt atctgctaac gctcccccca
     3601 tttggactgc tgttccttca cggccaacag atcccccaaa taaatgggta gttatggttc
     3661 caaacagtgt aagtggaata agccgcaacg ggattttttc ttctccacca tttccttgat
     3721 cgatcactaa gttgtttcca cgactagaaa gtccgccgtg atacgcatag agataagcaa
     3781 aaagcgcacc actaactggt agtagacaaa ggagccaagg atgtgatagt cggatatctg
     3841 tcacaactgt caggctattt aagaaaaaag cagacaagct ccccatgaat ataccgagaa
     3901 tcgctgtgat caccagccac ttcagcatat acactaaaat gcgtactgga ctcggtaatt
     3961 gtttttccat aaaaaattcc tcctcaataa aaaaacgcct actaaagaaa ggggctgtcc
     4021 ccagacttta gtaggcgtca ttagctatct ttcgttagca tttaaaggcg aacaccatca
     4081 cctattcact tccattaaaa gatagcatat ttttctgtaa aaaacaataa aattatcgtt
     4141 ctttctttac acgttcagca aattcataga aaggagccaa tttcgttaac tgttgattac
     4201 attggtcact atcatgacaa atataattcc cctttttcgt atacgtgcca tcagaacctg
     4261 ctttcgttgt agaaagaaaa agcgaaacat tcgatgtttt ctgacagatt gcacagattc
     4321 ccttatttat cgttggtgat aaagtaccgc taatcccttt taatttttca tcttcgtaat
     4381 agaccatgaa ttttttctgc gtacctggat cattccagcc gatgtacgta tgttcttgca
     4441 agtcgatttc attccaagct ggttgtttga gttttttcac ttttcggaat aatttctcga
     4501 tttgtggttt gctaggctgc ataaacggct gaacgatttg cttcagctcc tccaatgctc
     4561 tttctgcttg cgcttttgtc agttttacgt ctaaaactgt cgttaaaaat gtatcgattc
     4621 tggcagttcg tgatctaata tgtctcgaat cttttcagct gctagtgcct gaactgtttg
     4681 taccgttttt ggatcattga cagatgagta cgcatttaat aactgttcta cttctcttat
     4741 tataaaaaaa tattggtatg gttttattgt ttgttccatg attttaaagt cctttcttct
     4801 aaccaaagtg catactttgt agaaaaaagt gatcttctgc aaagtatgtg ttacctgaag
     4861 atcccggact cttttaaata agatacgttt tgcatcttat catcaccccc tttaatgctt
     4921 attattctat gtacatgatt cattcgataa ataaaagtaa accgtatctt gaacagatag
     4981 tcaactgcaa acagaaaaaa ggactgtgac aaaagtcgtg tcaaagtccc ttgtttcgaa
     5041 tgaatggtgt tcaaaagctg gcatctgcgg taataagccg aaacttcaca aaaatttgag
     5101 aagcaatttt cgtaaattcc ttcttatttc ttgaagctga ccacttctgt cacaacctca
     5161 atatggtcta ttattggttt tatctattaa atcgaggatt ctttcccaaa gtaacgttgc
     5221 catctcttac gcatacttgg tgacataggc tgagcggctt ctttgactgc gcagtatttg
     5281 tctacgaatg ttacgatata tccttctttg tacttaggcg gtgcaatcgt tgcgccccac
     5341 atgtgcttca aaatgatatc tcgctcaaga tccgacaatt cggtgatctt ttctgcattc
     5401 tttacagcaa ttcttggatg gatatacgca tgtgtgcctt catcaaattt cgtcgtacgc
     5461 caatcatagt agaacagatc atgcaaaagt ccagcacgcg ctgttgcttt agcattgcca
     5521 ccccattttt ttgcgagcag ataactatag taagaaacac tgatggaatg ctccaaacga
     5581 gtggaatgaa catgctgtgt gtaattcgct aattttttca ctgcttctgt ttctaaaaga
     5641 tcttctacat aagacatata ttcttcgtct tcacgccatt tttctgtcat aattatcgat
     5701 ctgccacctt tttgaatttc attttcttct gaaattgatc taagtatacc accagtgttc
     5761 ggattattct agtcgccttg gataaaatag ccaaagctta atagttcctt aatcataaag
     5821 aaaaatgata aagaacaatc cctgccgcaa ccccaacatt caacgattcc gcatttcctt
     5881 tcatcgggat atatacgttc tgatcagtca aagacaagat ttcctgactt accccctgac
     5941 cttcgttccc catgattatt gcgaagttat ctgatttttc tactttgtct aatgcgtgtg
     6001 cttcttcatt taattctgtg ccatacactg taaacccttt gtctttcatt aaaggaatca
     6061 cttctgtcaa atctttttgc aacacaggca aatgataatt gcttccctgc atgctgcgca
     6121 gcacctttgt actataaata tctgccgttc ctttgcctaa taaaacacca gccatatcaa
     6181 atgcatctgc cgtacggatc atcgtcccta catttccagg atcttgtaca ttatctaaca
     6241 acagccatcc tcctgaaaaa tctggcgtgc cttcagccgt taacgccatc actgctaaga
     6301 ttccttgtgg tgtaggtaga tccgatacag catccatgac ctcatccgaa actagaaaag
     6361 tagaaatctc tttgtttgcg gccagccagt ctccccattc tttcatgcct cgctgtgtca
     6421 caaaaagttc ttttatttct gcatcagacg acgcagcttc ttcaatcaga tggaaccctt
     6481 ccaaaagata ttcttccttt tcttcccgat atttcttttt atgtagtttt tttaattctt
     6541 tgattcttgg attttttgct gattggatct ctttcacatt cctcacctcc ccatgattat
     6601 atcatggaat aggtgcttga gcttgtttca tcctaaaaaa atcggtatca ttaatttata
     6661 aaataggaaa gaaaggtgac gaacatgcgc aaagttaaaa tgaacgtcca aggacgcgtc
     6721 caaggcgtag gatttcgcta catgaccaag atggtcgctg atcaactagg cgtgactgga
     6781 acggtaaaaa acgaagatga cggctcagtc acgatcgaag caatcggcaa tgacgacatc
     6841 atccagaaat ttattgaaga agtcaagaaa tctccgagcc caagtggacg agtgcagtat
     6901 gtggatgtcc aagaagaccc gatgattgag gaacgaaaga aatttgatgt ggtgggataa
     6961 ggttgtgaaa aagctggtct gcatcaagca ttaaggacag gttgtgaaaa atagctctcc
     7021 atatttttca acaggctgga cttaatgccg tagatgcaag cttttgaaca ccgtcgataa
     7081 ggttattctt gaggcgcttt gcctcaaaaa ttaaggacag cagtgaaaaa gctgatctat
     7141 cacttgcagt gagttcattt gactccgctt tttcgggcag aaaaaaagtt tttagtttat
     7201 taaagtaaga aagaaacact tggaatcatt ctactttttc ctagtatttc tttcttgatt
     7261 ttttgtcttt ttttcaaaat ttttcgctac gtaaaagaac gaatatttat atgaaatttc
     7321 tatgaagttg attgaattcc atgcgctttt ttagtatagt taagtttgtg taaaaattat
     7381 agaagaggaa gtattctatg aataaatgga aaaactggtt attgggatcc ggacttgtca
     7441 gtatcctgct ctttttatct ggctgtgtgc ggatggattc aaacggaaac cctgacactt
     7501 cgggaatcgt ttatcgagta ctcgtccatc ctatgggcca agcgattaca tatctagttg
     7561 aaaatttcaa ttggtcttat ggctgggcag ttattgcaat gactgtgatc gtccgtatca
     7621 tcatcttgcc actaggtatt agtcaatcga aaaaaacaat gatccaatct gaaaaaatgc
     7681 aagcgttaaa accacaagtt gaagcagccc aacaaaaatt gaaagctgca acaacacgtg
     7741 aagaacaaat ggcagcacaa gcagaaatgc agcaagtata ccgcgaaaac ggattgagta
     7801 tgaccggcgg aatcggctgt ctgcctctat tgatccaaat gccgatcttc tctgccttgt
     7861 actttacggc acgttataca gaaggtatcc gggaatcatc tttctacggc atcgatttag
     7921 gctcaccaag tatggtactt gttgccattg caggggtcgc ttatctgctt caaggataca
     7981 tctcaacgat cggtattcct gaagaacaga aaaagacgat gcgtacgatg ctgatcgtct
     8041 ctcctgctat gatcgtcttc atgtcgatca gtgcgccagc cggtgttaca ctttactggg
     8101 tagtcggtgg tgtgttcagc tgtctgcaaa cattcatcac aaacgttatg atgaaaccac
     8161 gtttgaaagc acaagtggca gaagagttga aacaaaaccc accaaaacaa gtcgtcactc
     8221 caagaattga tgtgacagaa tcagctaaac cagctgacag caaacaagca accaaacaaa
     8281 tcaagcaacc caaaaacagt acaaacaata aaggccgcaa cgcaggaaag cagcagaagc
     8341 ggaagtagat agtaaataag agtgtaataa aaattcatta acagttttag caattaaaaa
     8401 tatcgaccaa gatttttgaa aaagaaatct ggtcgatatt tttatttaag tgaatgttta
     8461 atttgaatca tcgattgatc gctatctaat tgcagcagca tctttttatg aagaaacaac
     8521 tttttcttat ctatcaacgt agacaggtgt tgctgtttct tctaatagtg tacttaattc
     8581 cttaatattt tgttttcctt cttctaacat ccaactactc gctttttctt cgccttcggt
     8641 aacaaaaggc gccactccct tcgcccatgt tgctcgccca cataagacac cattctccat
     8701 aaaggacaac gcggagatac cacccatcta aataacatcc ataaaccttt ctagtagaag
     8761 aatagtgata gtatccatcc ctttttctac tgggaataca attacacgat tcaaagcttg
     8821 atacacaaca tttcccttct tataaaccgc tattgtaacc gaattgtttt gaatcacctt
     8881 tttgggatag aaactggctc ctttccgcaa cttcttaaat gttggtttct tttatacttt
     8941 ctttgtagca actacaaatt tcttcaaatc tctaaatgtt tgcataacaa ccgcctttct
     9001 gacttttact caggatggta tttaaaaatc agcaaaataa ggcttctctc catctttttt
     9061 atttcctagc tgctttaaag acactcttgc tgttttttaa tctctatcaa gggggctctg
     9121 aatctatttt gatgaactta tcttattaat ttctcaaatg agctgtcaga cacaactgta
     9181 ttttttcaat ctcataccgg acaactatgc cagcttaaaa aaatttcctc tggcaaaact
     9241 tctttattga aaaatgacaa tgaaaaaaga ccattctttt tgttgaatgc tcattgtgta
     9301 aacatatttc ctgcgactgc tcttcgaacc attctcagtg caatccctaa tttatctatt
     9361 aaatcttctt ttagttcctc atctttcata ttcaaaattt cctttgtatg ttacacaagt
     9421 ttgttctcta aataacgcga attgtaaaat taagttagaa aaataaaaag gcatttatgg
     9481 tacactcaaa ttgt
//
LOCUS       DAFEIE010000082         9413 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFEIE010000082
VERSION     DAFEIE010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.085"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(42..680)
                     /gene="plsY"
                     /locus_tag="LP345_002461"
     CDS             complement(42..680)
                     /gene="plsY"
                     /locus_tag="LP345_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBL1761220.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            807..1241
                     /locus_tag="LP345_002462"
     CDS             807..1241
                     /locus_tag="LP345_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBL1761221.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1407..3452
                     /gene="parE"
                     /locus_tag="LP345_002463"
     CDS             1407..3452
                     /gene="parE"
                     /locus_tag="LP345_002463"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBL1761222.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3464..5914
                     /gene="parC"
                     /locus_tag="LP345_002464"
     CDS             3464..5914
                     /gene="parC"
                     /locus_tag="LP345_002464"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBL1761223.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6191..8422
                     /gene="pflB"
                     /locus_tag="LP345_002465"
     CDS             6191..8422
                     /gene="pflB"
                     /locus_tag="LP345_002465"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBL1761224.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8666..>9413
                     /gene="pflA"
                     /locus_tag="LP345_002466"
     CDS             8666..>9413
                     /gene="pflA"
                     /locus_tag="LP345_002466"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBL1761225.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTK"
BASE COUNT         3323 a         1627 c         2037 g         2426 t
ORIGIN      
        1 tttgtcacac tcccgtttta tctctttgga atgaaaaagt atcaggattt tttcttgctg
       61 ctattcaaac caaacgggat tcgactttca gtatggtttc tgatacgctt gatattgtct
      121 ttatgccgat aaaagataaa ggaagaaact aaaaaggcaa tgatcgtcag taaccaattg
      181 ggcttagcca aaatcacagg agctacataa ggaaggacga tcgtagataa agtgatcaat
      241 actgcactga tcatactgct caaactcacc atacttgtac aaaataaact aacgataaag
      301 atgatacaag aataaacaaa aaatacagga ttaaatccta aaagcattcc tgcacttgtc
      361 gcaacagctt ttcctccttt gaacccagca aaaatcggaa atgtatggcc aagaatggcg
      421 cataccccaa accaaagagg gttaatccca gaaaggtgga agatcatcgg caaacaagta
      481 gccaatgtac cttttaaaat atccataagc aggacaacaa tcccggctgt tttgcctaat
      541 acacgaaatg tattggtcgt tccagtatta ccgctcccgt gttgtcggat atcttttttg
      601 aaaaacaatt tgccaatcca gacaccggaa ggaatagaac ctaaaagata tgctaaaata
      661 agtaataaga tcaatttcat tttttaccct ctttcaagtt gaaaactatc ctttatttta
      721 gcatgaatag gtaacaggaa caattgaaaa aatgaaagat acaagtataa tagatggaat
      781 aaaaagaaaa gcaaggggtg gcagaaatgt ctgtaaaaaa tccaacacaa gaaacgattt
      841 tcaactattt ggaagaagca aaaaatattg ccgtcgtagg cttgagcaat aaaccagaac
      901 gaacaagtta catggttgca caggtattgc aagacaatgg atataaaatc ataccagtaa
      961 atccattatt ggctggtgaa gaaattctag gcgagaaagt ctatgcgaat ttgacagaaa
     1021 tcgatgatcc aatcgatatc gtagatgtat ttagacggag tgaattttta cctgaaatag
     1081 caggtgattt tttgaaaact gatgctaaag tgttctgggc acaattaggg attgaaaaca
     1141 aagaagcagc tgagatgcta agaaaagcag gacgtacaga tatcgtaatg gatcgttgta
     1201 ttaagattga acttggtaag ttgaaagaaa accaaaaata aaaatgacca caaagaagag
     1261 atgatcgata gaggggaatg tcgaaaaagc ggttaggaga taattaaaat tgatttctcg
     1321 tctaccctct tttttttcac gaccttttct agtatgataa tcgtggtgcg gttttgccgc
     1381 aaagtattat tgaaggagcg tttgccttgg caaaaaaagt aaacaacgaa tacaatgact
     1441 cgtccatcca agtattggaa ggattagagg cagttagaaa aagaccaggg atgtacattg
     1501 gatccactga cagccgaggc ttgcatcatt tagtctatga aatcgtcgat aatgcagttg
     1561 acgaagcatt atcaggttat ggcagtgaga ttgatgtgac catccatgaa gacaatagta
     1621 taactgttgc agatagcgga cgtgggatgc ctgtaggaat gcatgcttcc ggaataccaa
     1681 cagttgaagt gatttttact gtgctgcatg ctggcggaaa gtttggtcaa ggagggtaca
     1741 aaacttctgg tggactgcac ggtgtaggag ccagtgtggt aaatgcctta tcgaaatggc
     1801 taattgtaac gatcgttaga gatggcgtag agtatcagca gaaatttaaa aacggcggta
     1861 aacctgacgg tactttgaaa aagataggaa aaacaaaaaa agcaaacggg acgactgtcc
     1921 attttttacc agatgataca atattcagta caacgaaatt ttcatatgaa attttagccg
     1981 aacggttaag agaatctgcc tttcttctaa aaggcgttaa aatctctctt tctgatcttc
     2041 gtggagaaga accagtcaag gaaatttttc attacgaaga aggaatcaaa gaatttgttg
     2101 attatctgaa tgaagaaaaa gatacattga caccagttgt ttatttttca ggagaaaaag
     2161 aaggtatcga agtagaggtc gcttatcaat acaatgacgg ttattcagaa aatgttttat
     2221 cttttgtcaa taacgttcgg acaaaagatg ggggaaccca tgaagctggt atgaaagcgg
     2281 cgatgacgaa atcttataat gaatatgcga gaaaagttgg tttgctgaaa gaacgggaca
     2341 agaatctgga aggtagtgat ttcagagaag ggttagctgc tgtactttct atccgtgtac
     2401 ctgaaaatct tctgcaattt gaagggcaaa caaaagaaaa acttggtacg ccagttgctc
     2461 gtaccgtagt agataacgtc atcagtgaac aaatgggctt ttatttgcag gaaaatagcg
     2521 aaatgagcca gatgttggtc cgtaaagcaa tcaaagccag agaagcgaga gaagcagcac
     2581 gtaaagccag agaagaaagc cgaaatggga agaagcgtaa aaaaggcgaa tctcttcttt
     2641 caggaaaatt gacacccgca caatcccgaa accctaagaa aaatgaattg tatttagtcg
     2701 aaggggattc tgctggcgga tctgctaaac aaggaagaga cagaaagttc caagcaattc
     2761 tacctttacg aggaaaagtc atcaataccg aaaaagctaa aatgcaagat atcttgaaaa
     2821 atgaagaaat caatacgatg atctatacga ttggtgcagg agtcggtcct gagttttcta
     2881 tcgaagactg taattacgac aaagtaatca tcatgaccga tgcggataca gacggcgccc
     2941 atattcaagt attactgctt actttctttt atcgttatat gaaaccgctg attgaagctg
     3001 ggaaagtata tatcgcgtta ccgcctttat ataaagtatc caaaggacaa ggaaagaagc
     3061 aagtcattga atatgcgtgg acagatgacg aattggcagc aatgattaaa aaagtcggca
     3121 aaggatatat gctgcagcga tataaaggac ttggagagat gaatgcggaa caattgtggg
     3181 aaacaacgat ggatccgact tcccgtacgt tgatccgcgt ccgtatcgat gatgctgcgc
     3241 aagctgaacg tcgagtaacc acactgatgg gtgacaaagt agaacctcga agaaaatgga
     3301 tcgaaaatca cgtgcaattt acgctcgaag aagatggcag tatcttagat aaaaaagagg
     3361 atactgaaat ctctccttca gtttctaatg atttattaga tgaagaacga gcagataaaa
     3421 atgaaaacaa tcagttattt gaagtagaat aggaggtcac ctgatggaaa atcgacaaga
     3481 agtacaagaa ttaactttag aagaagtgat gggtgaccgc ttcggacgtt attccaaata
     3541 tattatccaa gaacgtgcac tgcctgatat ccgtgatgga ttgaagccag tgcaacgccg
     3601 gatattattt gccatgaaca aagatggcaa tacgtatgac aaaggattcc gtaaatcagc
     3661 aaaatctgtc ggaaatatca tggggaatta tcatcctcat ggtgaccgca gtatttatga
     3721 agcgatggtc cgcatgagcc aagactggaa gttgcgggaa gtactgatcg aaatgcacgg
     3781 gaataacggg agtatggacg gtgatccacc tgctgcgatg cgttatactg aagccagatt
     3841 atccaagtta agtggagaga tgctagcaga tatcgagaaa gaaacagtcg atctcgtgtg
     3901 gaattttgat gatacagaaa aagaaccaac agtccttcca gctcgatacc caaaccttct
     3961 cgtcaatgga tcgacaggta tatctgctgg atatgcaaca gaaatcccga ctcataactt
     4021 agctgaagtg atcgatggca caatctatat gatcgatcat ccacaagcga gccttgaaaa
     4081 attgatggaa tatattcctg gacctgactt tccaacagga gggatcttgc aaggaaaaga
     4141 tgaaatcaaa aaagcttatg aaacaggacg aggaaaagtt attcttcgtt cgaaaacaaa
     4201 gatagaggca atgaagggta ataaacagca aatcgtgatc acagaaatcc catatgaagt
     4261 aaataaagcg accttggtga aaaaaatgga tgagatccgt ttgaataaga aaatcgatgg
     4321 aatagctgaa gtacgagatg aaagtgatag aacaggtctg caaattgtcg tcgaattgaa
     4381 aaaagacgcc aatgctcaag gaattttgaa ttatttgttc aaaaacactg agctacagat
     4441 caattacaat ttcaatatgg tcgctatcga ccatatgact ccgcatcaag ttggactgaa
     4501 agacatttta agaagttata tcgagcatcg aaagcaagtc ataacaaaac gtagtcaatt
     4561 cgatttagcc aaagctcaaa aaagacagca tatcgtagaa ggattgatga aagctttatc
     4621 gattctggat gaagtaatcg caacgattcg tgaaagtaaa gacaaaaaag acgccaaaaa
     4681 gaatttagtc gacgtctttc aatttacaga agaacaagca gaagcaattg tcacattgca
     4741 attataccgt ttgacgaaca cggatatcac agagcttcaa aaggaatccg aaagcttgat
     4801 tgcgcaaatc acagagttga ataaaatcct ttcaaatgac aaagagcttt tctctgttat
     4861 gaaaaaagaa ttgcgagaag tgaaaaaaaa ttattcttcc gctcgtctaa cgacaatcga
     4921 agacgaaatc gaagaaatca aaattgatac gcaagtctta gtggcacaag aagacgtaat
     4981 tgtcagtgtg acgcgagaag gctatgtgaa gcgaacaagc cttcgttctt atagtgcttc
     5041 caaaccagaa gaaatcggga tgcgagaagg cgactacttg ctatactcag gtgaattgag
     5101 tacattggac catgttcttc tgatcacaaa taaagcaaat gtgatctacc gccctgtcca
     5161 tgaactaccc gatttgaaat ggaaagatgc tggtgagcac atttctcaaa caatctccaa
     5221 tctgtctgta gacgaatcga ttttagctgt tttcccatat caaaaaattc aagcagagaa
     5281 aacatttgta ttcatcagca agaatggatt gatcaagcaa acacgaatga cagagttcga
     5341 accatggcgc acctataaga gccgtccgct cagctgtatg aagctaaagg cggaagaaga
     5401 tgaactgatt gctgtgtatc tgaaagaaga tcagccaggc ttagatgttt tcttagtaac
     5461 gcatcaagga atgggtttgc gctatccttt aacagatgtt cccgttgttg gagcaaaggc
     5521 agctggagtg aagtctatga atttgaaaga tggagatagg attatcaacg ggctgcttgt
     5581 gttagcagaa ggtgatacgc cgatcgtaat cgttactcag cgaggagctg ttaaacgcat
     5641 gcttgctcaa gaaatcagcc aaacttcacg tgcgaagcgg ggagtgacgg tcatgcgtga
     5701 gctgaaaaaa aatccgcacc gtattatcta tatgtcggaa ggaagatcaa aagaaataac
     5761 cttgatgaat caaaaagggc agcagttaac gattgaccca actgatttcc ctataggtga
     5821 tcgaacatcg aatggatcat ttgcgatgga tgagaaaaaa ggtggagaag tcatcgaagt
     5881 tatcgatgct cctgagattt tcatcgagtc gtaactgttg tagtatttta atgaagagac
     5941 gccatctgta ttaatacagg tggcgtctct ttttcattca tttttaataa atccttatac
     6001 gtttgcaaaa aaagatgaaa gtgttcacaa tgcttaaatg ttggtatgtc aacgttgatt
     6061 taaatatatg taaataaaac ataaaaattg ttaaataaaa aacaagaaaa cccttgcaaa
     6121 gatagggtgc tgtgttatac taatcacgta aaaactgtta cataaaacag aaatttagga
     6181 ggtccataca atggagcaat ggaatggatt taaaggtacc aaatggaaag aaggcgtaga
     6241 cactagagac tttattcaaa ataactacac tgaatatcgc ggtgatgaca gctttttgga
     6301 aggcccaaca gaagcaacag aaaaattatg ggatgaattg caaaagttaa atgatatcca
     6361 attcgagcgt aacggtgtct atgatatgga cacagaaatc gtatcaacta ttacttcaca
     6421 cgatgcaggc tatttggata aagatttgga aaaaatcgtc ggtctacaga cagacaaacc
     6481 tttgaaacaa gcattcatgc cgttcggcgg aatcaatatg gctaacaatg cgctaaaaag
     6541 caatggctat acaccaaacg atgaattgac acatattttc actgactggc gcaaaacaca
     6601 taatcaaggt gtatttgacg cttatactgc tgaaatgcgt gctgctcgta aaaacaaaat
     6661 cattacaggg cttccagacg cttacggtcg cggacgtatc atcggtgact atcgtcgtgt
     6721 ggcattgtat ggaatcgact atttgatgga acaaaagaaa aaagatcatg atatgactgg
     6781 ttatcataca atgagtgaag aagtgattcg tttacgtgaa gaaatcactg aacaatatcg
     6841 tgcattagcg caaatgaaag aaatggctgc gaaatatggc tatgatattt ctaaaccagc
     6901 tgcaaatgca aaagaagctg tccaatggct atacttcgga tatttagcag caatcaaatc
     6961 acaaaatggt gctgcgatgt caatcggacg tatctcagca ttccttgata tctatatcca
     7021 acgtgatttg gataatggag taatcacaga aaaagaagca caagaattga tcgaccactt
     7081 agtaatgaaa ttacgtatgg tcaaattcgc gcgtacacct gaatataacc aattattctc
     7141 aggattccct atctgggcta ctttatccat tgcaggtatg ggattagatg gtcgttcatt
     7201 agttacaaag aatgatttcc gtctgcttca tacattaaca aatatgggac cttcaccaga
     7261 accaaacttg actgttttgt attctgaaca ccttccagaa ggattcagaa catatgctag
     7321 cagaatcgct atcgaaagtt cttcgattca attcgaaaat gataatcagc ttcgtgaaca
     7381 atggggttct gatgattgtg cgattgcttg ctgtgtatca ggaacagttg tcggaaaaga
     7441 catgcaattc tttggcgctc gtgctaactt ggctaaaaca ctattatatg ccatcaatgg
     7501 cggagtcgat gaagtgactg gcgcccaagt tggaccagaa tatcgtccaa tcacatcaga
     7561 aatactagac tttgaagaag tgaaacataa cttcatgaat atgatggatt ggttagcaga
     7621 actatatgtc aatacgttga acatcattca ttatatgcat gataaatatt cttatgaagc
     7681 agctcagctg gctttgatgg attctgactt gcaacgcaca tttgctacag gtattgctgg
     7741 gatctctcat gcggcagaca gcttgtcagc gatcaaatat gcaaaagtaa aagcaatccg
     7801 taatgaaaaa ggaatagcag ttgattttga agtggatggc gacttcccta aatacggaaa
     7861 tgatgatgac cgtgcagatg aattagtttc atggatcttg gaatacttca tgggacaaat
     7921 caaacgtcat aaaacttacc gcaactcaaa accaacaact tcattattga cgattacttc
     7981 aaatgttgtt tacggtaaaa atacaggaaa tactcctgat ggccgtgaag ctggaaaacc
     8041 acttgcgcca ggagcaaatc caagttacaa tgcggaacaa agtgggttat tagctagcct
     8101 gaactcaaca gctaaaatga attacggctg tgcattggat ggaatttcaa atacccaaac
     8161 aatcaatcct tcaggtcttg gaaaagaaca agatacaaga atcgaaaact tgcgtaatgt
     8221 cttagatgga tacttctcaa aaggagctta tcatttgaat gtcaatgtat tcagtaatga
     8281 tttattgcgt gatgcaatgg aaaatccaat gaaatatccg aacttgacga tccgggtatc
     8341 tggttatgca gttaaattcc gtgacttgac aagagaacaa caattagatg tcttgatgag
     8401 aacttcacac gacagaatgt aaaaagttcg tgaaaaaagt ttttcgactt agcgtcgaaa
     8461 ggacgttgaa tagccatcgc atcaaaatcg aataatcagt atgcttattt gaaagaaacg
     8521 atttacaggg gcaggacttg tatgttccgt ccctgtaaat tttacacata acgaagcggc
     8581 aattgcgaaa aattttgttc agaaagcttc gcttcgacag ctaacttgta cttaaaatga
     8641 aatcaaagaa aagatgtgaa cttaaatgga agaaaaaaca atcggctatg ttcattctat
     8701 cgaaactttc ggttcagtag acggacctgg actgcgcttt gtcgtgttta tgcaaggatg
     8761 ccgcatgcgt tgccaatttt gtcacaatcc agatacttgg aatattggcg gagggaaaga
     8821 atacacagca gatgaacttt tagataaagc agaacgcttc agaccttact ggggagataa
     8881 aggtggtatt actgttagtg gtggagaacc tctattgcag atcgattttt tgatcgaact
     8941 atttaaaaaa gcaaaagagc ggaagatgca tactacattg gatacatgcg gaaaaccttt
     9001 tacgtatgaa gaacctttct tttcacgttt tcaagaattg atgaagtata cagatttact
     9061 gttatttgac atcaaacaca tcgataatga agagcataaa aaactaacgc attgggacaa
     9121 tgaaaatatt ttagaaatgg ctcaatattt gtcaaaaatc aacaaaccgg tttggattcg
     9181 ccatgtacta gttcctgagc gaagtgatta tgatgaatat ttgatccgac tagacaactt
     9241 tattcaaacc ttgtcaaatg tagacagagt agagattctt ccttatcata cgatgggaaa
     9301 atacaagtgg gaaacacttg gtttgaaata tccattagaa gggatcgaac cacctacaaa
     9361 agaacgtgtc gaaaatgcta aacgattgct tcatacagaa gagtatacaa aat
//
LOCUS       DAFEIE010000083         9209 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFEIE010000083
VERSION     DAFEIE010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.086"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            470..2107
                     /locus_tag="LP345_002467"
     CDS             470..2107
                     /locus_tag="LP345_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761226.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2252..2992)
                     /gene="truA"
                     /locus_tag="LP345_002468"
     CDS             complement(2252..2992)
                     /gene="truA"
                     /locus_tag="LP345_002468"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL1761227.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3183..3818)
                     /locus_tag="LP345_002469"
     CDS             complement(3183..3818)
                     /locus_tag="LP345_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBL1761228.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="LP345_002470"
     CDS             complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="LP345_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBL1761229.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5404..6400
                     /locus_tag="LP345_002471"
                     /pseudo
     CDS             5404..6400
                     /locus_tag="LP345_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            6416..8434
                     /locus_tag="LP345_002472"
     CDS             6416..8434
                     /locus_tag="LP345_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBL1761230.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8494..9186)
                     /locus_tag="LP345_002473"
     CDS             complement(8494..9186)
                     /locus_tag="LP345_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBL1761231.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT         2978 a         1706 c         1445 g         3080 t
ORIGIN      
        1 actaatcaga atcgtacaaa tatttaataa ccaaatatat agaacataac ttaatattaa
       61 gttatttgaa attccataaa aaacgactgc aggaattatt gtaagaaaag gataaaaata
      121 gttcagtcca tctccataat tgttaaatgt tgtatagttg attggccctt caaaaataga
      181 agataaccct ttgattcgtg aaagatgaaa agataaatca cctgttgtat aaatttcttg
      241 agcatttctc ataaaattta ctgaatataa agtactaagt aagataagaa ctactaaaag
      301 aaatgctttt ttacttattt tcatagattt gttgttctcc ttttttaatt ctattttcag
      361 tatactagaa ttgtcttttt ttaataagtt ttgcgttaaa tttttcatag cactagtatg
      421 atatactaga aaagaatcaa tttttattac ttttaaatag gagaaaaaaa tgaaaaaaaa
      481 caaaaaccaa ataatagata tcatttttat gttatttcta agttttgctt acgtcatccc
      541 tctattcatg tctatgggaa tctatcatag tgtcaatcag gatacttact ttcatttatc
      601 tcgaatcata ggactagata atgtatggag ttctccagta aacttcaata acttcgatca
      661 tcatggaaca atgatgaata ttttttatcc atggcttact ctttatccag cttttttatt
      721 ttataaaatg atgggaaatc ttgttttaag ttataatatc tactattttt ttatcacttt
      781 tttaacaatg gtcgtttctt atttttctat gaaacaaata aaaaacaatc gttatatttc
      841 gctgttattt tcgattattt atacattttc cgcctatcgt gccattgaca tattccatcg
      901 tgcttcattg ggagaagctg tcgctttaac atttttgcct ttgatactaa tggggtgtta
      961 cgaaatttat attagagatt accaaaaatg gtactggttg tctattggca tgacgctagt
     1021 agtgtatact catttacttt ctgtcgctat ggtttctgta tttattggag gaacgttgtt
     1081 tctttctttt tatttttggg accaaaaaat cgctagactc ttaagtcttt taaaagctac
     1141 cgtcctcacc ttttttttaa gtgcgggatt cttaattcct tttattcaac aatctagagc
     1201 acaagaattg aaagtcccac tgggaaaaga attaagtggt atggctccta gtgatatgct
     1261 gacacacatt ttaaataata actataacaa ctatactatt ggattattct tatttctcgg
     1321 attgattggt gcttttattt ttataaaaaa attaactgct gatgatttat ttattttctt
     1381 tcttggtgta tttgttcttt tttgttcaac caatttattt ccttggcaac tttttaacca
     1441 tacaccagtt aagagtctac aatttgtctg gcggttaaat ggtttttctt ctttatttat
     1501 agcctatacg atgagtatag tgatctatta tattttttct actaaaaata attcatggaa
     1561 aataatggtc tttacgtttc ttgcactaat attgcatctc tcaggagtaa gcaattctat
     1621 ccatgctaac aaagattcat taacacttat agcacctgaa gacgctgttg ctatagctga
     1681 aaattacaat catactgatt atgcaaacaa agagtcaatc tatcatcctg atatgattaa
     1741 taatgatcaa tatttactag gtaaccagga aataaatcca acaactcatt ttatgagtaa
     1801 caaacttaca attgaattag ataattcgaa taataaaaat actgtcttga cgacacctat
     1861 ttatcgttat aaagggcaag tggcttctat taatggcaaa ctagtacaaa caaaattatc
     1921 taagtttggc acaactgaat taactattcc tccaggtata aataaagtcg ttattactta
     1981 tcagtacaca aaactagcaa ttgcttcaag atatttatct atcgttactt tgattttatt
     2041 tttactttat cgatttactt tttctaaaca aaaacaaccg agaagagaag tacaacattc
     2101 tcactagatt tttatttaag aaagactttt tagctgtaca cataaacagg ctaaaaagtc
     2161 tttttttata tttctttaat ttgcttcata cattatttaa catcgatatt tatactgtga
     2221 aacatgcgtt tcatccatta tcaaagtatt tttatcgata ataaacttca tccaaaaaca
     2281 gaccttgtgc agggacggtt tctcctgcat gttgccgcac tttgctttca aatatttcat
     2341 cgattgtttc tatcggcatg gcacctgtgc cgatttctag taatgtcccc atgataatcc
     2401 gcaccatttt atataagaat ccgtctccga caaaagtaaa atgaagcatt tctccctttc
     2461 gttcgataga taattcatca atcgtacgca ctgtggattt ttttgatttt ttcaatgcag
     2521 aaaaaccaat gaaatcatgt gtacccacta atttttcgca agctgcattc agcttgtcca
     2581 tatccaactc ttgagggaaa taaaagctgt ggtttcgctc aaatgctgaa ggaatcacgt
     2641 tgttccaaac ataatagctg tattttttgc ccaccgcatt atatcttgaa tggaagcgct
     2701 caggcatttc ttcgattctt ttgatgacaa tatcccgcgg aaggtaacga ttcataaagt
     2761 cgatcatttc tgccagtcca atttctgtgt ttgttttaaa atttgctact tgtcctcgcg
     2821 catgggtgcc agcatctgtt cttcctgatc caataatttc tatctcttca tttgtcatct
     2881 gatgcaatac tttttcgatt tttccttgaa tggttttatc gtcatctcca agtctttgcc
     2941 atcctgaata tctttttccg tcatattcga ttgtcaactt gatgtttctc atattttagt
     3001 ggctcctctg tcttccattt ggtcttctct ctaccttttt aagattgtag cacaaaatat
     3061 agctcctttc ttctctaaaa cagaagctat acaagaaaac tgtggaaata tatatttcag
     3121 aaaaacaaaa aacagccacc ggatgaagta tccgctgact gttcaatttg acggctcaag
     3181 ttttactgtt tgagatgcaa gatactcaac caggcaatgg gcacataatt aaagaaaaaa
     3241 ctgattcttt ggcaaaaacc tattttattc agtaatggcc aagaatttat agaaggaatt
     3301 cttgccagtc cataaatcgc cgcaaaaagc aaactgatca cagacagtcc aaggtataag
     3361 tggcttacgt ccatttgccc attttttcga tagatcaaga aaagaagaac tggaaacaat
     3421 aaaaaaccac tgtaacctaa acctgatccg atattatgga cccatgtcga gacattccac
     3481 gaagattcat gggtattgat actgaacaaa cctgtaaaga tacaatcacc tataccatag
     3541 aacgcgatgg ctgctgtaac tagggtagct aacacacgag atgtacttac aaatgcagca
     3601 tacaatgcag gcaatgacag gatgaaaaag atccctgaaa ccacagacca aataagaaac
     3661 gcttttctta caggactgga aacctctcca aatacactga tcacgctctt catttgatct
     3721 aattcaggat aatacaatcc taatacgtac ggagtcaaaa aatcactcag cacgcctaat
     3781 aataaaaaga aaaaaccaaa tttacgtaaa aaatccatga tacgcctcca ataacaatta
     3841 cctatgcttt taattgttat tataaacgac tttatcttga tttaacagaa acctctattt
     3901 acacgaacat ctatataact cattaaaaac tcgaatcatt ttaaaaatac taaatatcta
     3961 acgttcaacg ttcacttaat ccatctaaac aatctttcaa tttgattttt tccccacttc
     4021 ttttacgcgc gcctagctct cctattgcag taaacaacag atcacttgac gaatttaagg
     4081 cagtttccat tgaatcctgg ataacaccga taataaatcc aataccgacg atttgcatcg
     4141 cgacatcatt agagatacca aacaaactac atgctaatgg aatcaataac agtgaaccgc
     4201 ccgcaacacc tgaagctcca caagcagcta aagcagacaa aatacataaa aggactttca
     4261 aaacaaaagg tgcttcaatc cctaaagaat gtacagcagt caacgtcatc aaggaaatgg
     4321 taatcgcggc accgcccata ttgatcgtag cacctaacgg gatcgatatg gaataagact
     4381 cttttgtcaa tttcaatctt tcagccaaca tcatgtttat cgggatattt gcggcagaac
     4441 ttcgggtaaa gaaagcggga agtgcgcttt ctttcaaaca aaagaaaatc aatggatagg
     4501 gattttcttt aataaacaaa aacgtgagga atgggtacac aactaatgcg acaaacagca
     4561 tcgtaccgat caaaacaagt aaaagctgca gatactctgc caatccagcg attccagtcg
     4621 tagcaattga ttgataaacc aatcctaaaa tccctatcgg agcaaatgca ataatcactt
     4681 gtacgacttg tgacaacgct atagatatct gatccaccaa ctcttttgtc gattctgaac
     4741 gtgctcgaaa agctagtccc aacaatacag cccagaataa gacgccaagg taattcgcat
     4801 caataagaga ttgaacagga ttttgtgtga cattcgtcaa catagtagat aaaacacttt
     4861 ccaaactttg cggtgctttt tcagatactg tttcttgtaa agtaatagga acagtaaaaa
     4921 ttgaacttac aataactgct acaagtgcag aaagcaatgt tcccactaaa tataagatca
     4981 aaataggctt cacgaatgtc ttattcccaa ttttatgctt ggcaattgac gccatcgtca
     5041 agaaaaaaac cagaataggt gcgattgcct tcaagcaact gacaaacaac gttcccaata
     5101 ttgaaataaa tgtccatgtg gggaaaaaga taccaaacaa tattccgact aaaataccaa
     5161 caacaatacg ttgaactaac gacatatcca aaaacttctc taacaaatga ccaccctttc
     5221 acaattttaa caatcattgt atcattttat gcaaagaaac taaaggtata attttctaaa
     5281 aattctaaca atacaaacaa ccatttcttg ctaattttgt actttttctg tctacacgtt
     5341 gttttttgag atattctaag ttaggatgtt attaatgggc aacttatcag gaaacgtttt
     5401 cttatgtttt tgtccaattt ttttgtgagg tgtttattct tgaaaaaaat aaagaaggag
     5461 agttatggct tcctgacaat ctttgtcgct tgtataatga tggttttaca gcgtatattg
     5521 atttcagcag tcactattcc tacatatgca acaaaccctg gtcgattcta catctataca
     5581 tttttacaaa cttccgttgt tattggtgca aatttgatcc cactttacat gggttaccaa
     5641 tatcaaaaaa tcgcccgttt aaaagtttta cattatttaa gtcgttttgc ctttatattc
     5701 ctaatagcca cactagtttg caatatcttt tttttacgta caagctggca gcttgaatat
     5761 tcgtgattat tggcttatcc taacacctat cagtcagaat tactttactt atgctgtttc
     5821 ttgtactttg cttttttgta gtattcctta tacagttgga tttttaaata aattatcgaa
     5881 aacaacaatt aaatatctac tattattttt aacaattgga ttagttggct gctctactct
     5941 atttaataaa gacccgtttg cattacagaa tggacagagt attttatgga ttttttattt
     6001 atttttaatg ggttatggtt tgaaagaatg gaactggaaa gaaaaggtcc gctataagct
     6061 tcctcaagta tttatcagct tgattgtttt attcggtttg attattttga tgacacaaat
     6121 ttcactcatc atcagaggaa atacagatac agcgctgagg ttttctaaac catattctct
     6181 cttcgcaatg tattatactt tctcttcgtt tttattttta gaaatgctat ctgataaatt
     6241 aggtataaaa ggaagaggaa attttcttgc tgtatttttg attgtcactc aagttatatg
     6301 taatttccct ttagtttctt atcgcgtatc tacatttatg aaacgtgaat ttccaaactc
     6361 agggaaggca tggctgataa atatcgggca gttttttatt tgctatttat tagcagtgtc
     6421 cctcctagtt atctttttat tttatataca aaaaatccgt ttcattcatc gtttcatcga
     6481 atacttcgct tttgattcga ttgaacaatt aactcagcgt tggaaaaaaa gaattcattg
     6541 gctttttgtt cataaaagtt attttttagt tgcagcattt ttttactgct ttaccttcgt
     6601 gcagattttc gttttagaac caaaagaagg ttggaaagaa actatccagg ttgccttaaa
     6661 aatatttact cagcgacaag cacccatgat cctgacaatc atcattatta tgggattttt
     6721 cttcttacta ttgttgattt ccaatcgttt ttggtacgcc ttgactgcta ccttgatcat
     6781 taacttactg ctcactattt cgacagtaat caaaatggaa atgcgggaag agcctgtctt
     6841 tccttcagat ttaaaaatgc tgaccggatt gtcagaacta ttatcgatgg ttagcccagt
     6901 cttattaatc gtgggcggat tgatccttct cctattattg attactagta ttattgtaca
     6961 acgtagacta caaaaacagt attccttgaa gattcattgg aaacgtcgat ttatcagtat
     7021 cgctgtatta ttaggatgtt tttcgggtgt ctttttcatt aatcacaaaa attcgccttc
     7081 tttcttgctg tttaatttat ttaaagtaaa caagactttc tttaaccagc aaggcgccgt
     7141 aaaagataac ggaccagtca ttcaattcct aaacaatatc gacattaaaa tcatggaaga
     7201 acctgctggc tattcgaaag aaaaaattaa tggaataatg aaaaagtaca acacaaaggc
     7261 agatgaaatc aaccaaacaa gaagtgactg gttaaacaat cagacgatcg ttctcaattt
     7321 aagtgaaagc ttcagtgatc ctgcacgtgt ccctaatctg acagtaccta cagaccctat
     7381 tccttacatc aaaagcatta taacagaagg aacaggagga ttgatgttat ccgtcggtta
     7441 tggtggcgga acagctaaca tggaatggga aggactgaca ggcttgagta tcagtaacct
     7501 gtctgcttcg ttagttacac cttataccca gctagtggag cgtcagaaaa taagtccaaa
     7561 tattaccgat ctattcgatg aaaaaatagc catccatcct tttacagctg ctctttatcg
     7621 cagaaaacaa gtgtttgata aatttggttt tgacaggttc tattatttag acagtccgga
     7681 taaattaact tatacggata aaatagaaca aagcccacgc atatcggatg attcagcata
     7741 caaagaaacc ttgaaagctt tacaaagcaa tacagaaacg tcacaattca tccaattatc
     7801 cactatgcaa aaccatatgc cttatgatga ttactatagt gaattgaact acactgctga
     7861 aggaactgct gtcattccta atagaagaaa agaattacaa acttatatgc aaggccttca
     7921 ctataccgat acagcagtaa aaaaattcat ccaagaaatc gacaaaatcg ataaaccgat
     7981 tacctttgtt ttttatggtg accatttacc cgcaatctat agtgggaatg attcgaaaaa
     8041 atatggatta gaacagcacc agacagatta tttcatttat aacaacaagt atagtcgtga
     8101 acaagcagct acgttaaata aagaagttgt tgctcctaat aactttggtg ctatggctct
     8161 tgagcatgcg aatatcaaag taactcctta ctatgcgttg ttgacagaag tatctaatca
     8221 tctacctgca ttaacaattg atcctacaga aagcttgtct aatcgtttta atggaaaaca
     8281 ggtctttgtt acagaggata gtcaaattat ccaagaaaaa aatttaactg agaaacaaaa
     8341 agaaattcta gaagattatc gtctgataca atatgatctt gttgcaggta accagtacag
     8401 tgcaacatgg gcgacacaaa aaataaaaga ctaacaaata aactgagcaa ggggttgtga
     8461 taaaagacat gtcacaaccc cttgtttatc tcattaattt gcttgtccat aaacgatttg
     8521 attaaagcca tttttcaatt cattattcgc tgtctcgttg aagtaaagat aattatcggg
     8581 attcccctga ttttgttgtg tcaccaatac ttttggctga ttttgctgaa acccgaatag
     8641 atagacgtgc tttttcagat atggttctgt ctctgcatcg gaatagacgg ctgtgatttg
     8701 atagtctgct tgacctgtcc cactttctga ccattctgca gaaacaggca ctccaccaat
     8761 agccatcttc cactccccgt tcaaaatagc ttgagggact ttaagaccat ataagtccac
     8821 actcatttga ttcgtataac ttttgtattg ttgtcccatt gtttggcccc atttggtcat
     8881 aaatgcctct aattgtgcgg atttgtctgc attccacagt gtttgttcaa cttgttcgct
     8941 gctttctgaa gaggaagatg aagcctctac agaagaactt gaagtagatg tttgagttgt
     9001 ttcagtcgtt ttggaagact ctgacgaagt agaggtatct gctgtttctg tacttgctgc
     9061 agttgacttg ctctctgtgc tagttgttgt agtagttgca actgttgctt tcgctgtttc
     9121 ttttgttgat tcttttttcg attcattccc gttggtacaa ccagctaaca aaaaagctag
     9181 accaattgtt actaaaatcc tttttttca
//
LOCUS       DAFEIE010000084         9201 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFEIE010000084
VERSION     DAFEIE010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.087"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            110..1297
                     /locus_tag="LP345_002474"
     CDS             110..1297
                     /locus_tag="LP345_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBL1761232.1"
                     /translation="MLDEVLEIHKKNVGVLRMETTEAVQDDQDLAKMYTPGVAELSLM
                     IEKNHALARELTISGKLVAVITDGSAVLGLGNVGNQAGLPIVEGKALLYKNLAGVNAI
                     PLAIEQKSVDEIVQTIVNLQNSFAGIHLEDIAAPKCFEIEEKLQEKLSIPVYHDDQEG
                     TAIVVLAGLINAAKIQRKTLTELRVLINGMGASGVATARLLIAAGIKNLTLVDKQGRL
                     KKQDSTLNKYQRELLDHIHDTNNNASVLEDAIVGQDVFIGLSIGNVLTPEMIGKMNDN
                     PIIFALANPVPEITPDLAKESGAKLIATGSSKYPNQVNNILVFPGLFKGLLLSKANKV
                     DLSLQLEVAKQLAAKVAEPTVEKFIPNVFDEGVANVVSQAVLDYLQKLKENEDNIHAE
                     NIK"
     gene            1278..2582
                     /locus_tag="LP345_002475"
     CDS             1278..2582
                     /locus_tag="LP345_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBL1761233.1"
                     /translation="MLKTLNRIKIGFIPLSLYIILVLAYLAMTISNIVPENDMLVSLG
                     IMTVFAYLLEEIGKTIPILKDLGGKVLVVTFLPAFLVYKHWLPQSTVTVVSDFMNNNN
                     FLMFFITLLVVGSIASMNRQTLVKATSRIIIILILCDVIGSLIGTGVGILLGLSAWNA
                     YFFIVAPIMAGGVGEGAMPLSIGYAAILSGMGQNDIFGKILPCVMLGSLVAVLLSGML
                     KKIGEKYPQLNGQGNLIDGDDEHLENLKGSAKPVNIEKTLLAGVVAITIYFVAVYVEH
                     LLKSLLGFSIPSPVILLVSLMGAKMLGFIPKNIEEGGNSLYGFTVRGITPPLLFGVGV
                     AKTDWLELIEVFKNPATIVTIIVTVVAIVATAFIAAKFLKMYPVDTAIAVSCCSGQGG
                     TGALAILAAGDRMELMPFAQVAVRLGGAMTVTFAIFLMGLLS"
     gene            2608..3621
                     /gene="citC"
                     /locus_tag="LP345_002476"
     CDS             2608..3621
                     /gene="citC"
                     /locus_tag="LP345_002476"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HBL1761234.1"
                     /translation="MFDQTDIQRLFLKNNYIKDQWENLLLDSGIQKKQIEDFQHLDQT
                     LGIYHKEKLVGTVSYQNNVIKYIAVSEKYKDGGHTFNVLVSAIIQAMSQQEIFHYIVF
                     TKPRYQKSFNFLGFETIVSTPKIAVLEMGDSSIKQYLERIPKVNGEKKAAIVMNANPF
                     TEGHYYLVKQAANNNDWVYVFVLEKEQNLFSTKDRLKLVQQGLQKLKNVIVLSGGEYI
                     ISPATFPTYFLREDDEIAKEQMVVDATLFKERIATYLDISARYVGEEPLSPMTRSYND
                     ILETILPPEIKVHVLARKKTEQHQVISASQVRKAYLAGQLEKIKYMVPETTYQYLKNK
                     RER"
     gene            3625..3918
                     /gene="citD"
                     /locus_tag="LP345_002477"
     CDS             3625..3918
                     /gene="citD"
                     /locus_tag="LP345_002477"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HBL1761235.1"
                     /translation="MEINKSAIAGTLESSDVQIMISPNTEGIEIDLDSQVIEQFGKQI
                     KKVIYDTLAVYQIKNVKLKVVDKGALDCVIVARLKTAIHRSLGIQHQETPWEV"
     gene            3923..4828
                     /gene="citE"
                     /locus_tag="LP345_002478"
     CDS             3923..4828
                     /gene="citE"
                     /locus_tag="LP345_002478"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HBL1761236.1"
                     /translation="MMKERLRRTMMFVPGNNPAMIKDAGIYGADSIMFDLEDAVSMAE
                     KDSARMLVAEALKTVDYGDTELIVRINDLHSEFGRADIFAMVKAGAHVLRLPKTETSE
                     DITEVEKVIIEAENYHNVPIGRTLMMAAIEGASGVLNAPAIAKASDRLIGIAIGAEDY
                     VTNMKTKRYPDGNELFFARSMIVHAARAAGISAFDTVYSDVDDMEGFLNEVRLIHQLG
                     FDGKSCINPRQIPVVNTVYQPSIKEIKRSLDIISAIEEAKEKGSGVISLNGKMIDKPI
                     VERAQRTLMLAKASRLIDEEGNIHA"
     gene            4821..6380
                     /gene="citF"
                     /locus_tag="LP345_002479"
     CDS             4821..6380
                     /gene="citF"
                     /locus_tag="LP345_002479"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HBL1761237.1"
                     /translation="MHNKQRRSIPSSVLTKYKKEFQSVSLSPQTIQRCAPKVTTVTNQ
                     TNKLMHSIKEAIEKSGLKDGMTISFHHHLREGDFVFNQVMAVIREMGIKELTLAPSSL
                     TNTMNEMVIECIKDGTVTHITSSGMRGSLGEFISHGGMDNPVILRSHGNRPRAIESGE
                     LKIDVAFLGVPTSDDYGNANATVGKSVFGSLGYAKVDAQYADKVILLTDHLVPYPNTP
                     ISIPQTQVDYVVEVEAIGDPNKIGAGATRFTKNPKELKIAEMVKDVIVHSPYFKDGFS
                     FQTGTGGAALAVTRYLASEMEEKQIKASFALGGITKPTVDLLEKGLVEKVLDVQDFDK
                     GAAEGMARLENQQEIDASFYADPSNKGAVVNQLDVAILSALEIDTNFNVNVMTGSDGV
                     LRGAIGGHQDAATAKLTIISAPLVRGRIPTVVNDVTTLITPGKSIDVLVTEVGVAINP
                     QRKDLIAIFERIPQIPVFTIEELQQKAEKIVGIPEPLQFTDRIVAYVEYRDGSILDVV
                     RQVKEFEEERS"
     gene            6377..6934
                     /gene="citX"
                     /locus_tag="LP345_002480"
     CDS             6377..6934
                     /gene="citX"
                     /locus_tag="LP345_002480"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HBL1761238.1"
                     /translation="MMFDTGEIQEIEDILIHKEQRANLQSNLLSKYSNSSLMVFTLNI
                     PGPIKNNPMIEQVFRQGQQSIQQMFLKKKVEMTYTKEINLPSGLDWYVIVTEAPLNLK
                     KWLVTLEEQDALGRLFDLDVLFKKGEQITIVSRQALNHGERPCFICGKSAKVCARNRT
                     HTVKEMQKKIEQIVADSLKGALKHA"
     gene            6927..7790
                     /gene="citG"
                     /locus_tag="LP345_002481"
     CDS             6927..7790
                     /gene="citG"
                     /locus_tag="LP345_002481"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HBL1761239.1"
                     /translation="MHDNIQKIAQEAQLAMLYEVTCINKPGLVDPVDPGSHQDMDIFT
                     FLQSSVVLTPYFEEFIQTGLDRQHQPIEETFMAIRQIGLEAETAMFSVTNGINTHKGA
                     IFSLGIFLAICGRLTIWKVPCKKSFFQKEIQKMTKNLLNDFGKIDQTKPKAWTWGEYL
                     FVNHGLTGIRGEAKRGYPCVFDRGLPYYQAYQGSQQDKMIDTLLFLSMEVEDTNLIKR
                     SNNRHVFEEYQLLIRPYFELGGVKTIQGKKYLDYLNQQFKKKNWSIGGSADLLILTIF
                     LDKIMDKGWLC"
     gene            8024..8433
                     /gene="tnpA"
                     /locus_tag="LP345_002482"
                     /pseudo
     CDS             8024..8433
                     /gene="tnpA"
                     /locus_tag="LP345_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(9070..>9201)
                     /locus_tag="LP345_002483"
     CDS             complement(9070..>9201)
                     /locus_tag="LP345_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1761240.1"
                     /translation="RRREKIIRIFPNCVSANRLIGAVLIDQHDEWLSSSRKYIKFAK"
BASE COUNT         3213 a         1422 c         1860 g         2706 t
ORIGIN      
        1 tttaaaaata agcatcattt ttttaaaatt taaaatgaaa gggttttttt attttaaaaa
       61 aagtgttaaa gtggttttgt aattaaaaaa tgtaaaaagg agtgaaggta tgcttgatga
      121 agttttagaa atccataaaa aaaatgtagg tgttttacgg atggaaacaa cagaagccgt
      181 gcaagatgat caagatttag caaaaatgta caccccaggt gtagcagaac taagtttaat
      241 gattgagaaa aatcatgctt tggcaagaga attaacaatt agtggtaaat tagtggccgt
      301 tattacagac gggtcggcgg tattaggtct tggaaatgta ggaaaccaag ctggattacc
      361 aatcgtcgaa gggaaagcgc tgctttataa aaatttagca ggtgtcaatg cgattccatt
      421 agccatcgaa caaaaatcag tagacgagat tgtacaaaca attgtcaatt tgcaaaatag
      481 ttttgcaggg atccatttag aagatattgc agcaccgaag tgttttgaga ttgaagaaaa
      541 attacaagaa aaactttcta ttcctgtgta tcatgacgat caagaaggaa cagcgatagt
      601 tgttttagct ggattgatca atgctgctaa gatccaaagg aaaacattaa ctgaacttcg
      661 agttttgatc aacggcatgg gagcatctgg ggttgcaaca gctagactat taatcgctgc
      721 tggtatcaaa aatctaacat tggtggataa acaagggaga ttaaagaagc aagatagtac
      781 attaaataaa tatcaaagag agttgttgga tcatatacat gatacaaata ataatgcaag
      841 cgttttggaa gatgcaatcg ttggacaaga tgtttttatc ggtctttcaa taggaaatgt
      901 tttaacgcct gaaatgattg gaaaaatgaa tgataatccg attatttttg ctttagccaa
      961 tccagtacca gagatcacac ccgatttagc aaaagaatct ggtgcaaagc taatcgctac
     1021 aggttcttcg aaatatccta accaagtaaa caatatttta gtatttcccg gattgttcaa
     1081 gggactatta ctatcgaaag cgaataaagt cgatctttca ttacaacttg aagtagccaa
     1141 acaattagct gctaaggtcg cagagcctac ggtagaaaaa ttcatcccta atgtttttga
     1201 tgaaggagtc gcaaacgtcg tttcacaggc agttttggat tatttacaaa aactaaaaga
     1261 aaacgaggat aatatacatg ctgaaaacat taaatagaat taaaattggt tttattcctt
     1321 tatctcttta tatcattttg gtactcgcgt atcttgcaat gacgataagc aatatcgttc
     1381 cagaaaatga tatgttagtt tctttgggta ttatgactgt ttttgcttat ttattagaag
     1441 aaattggtaa aactattcct attttaaaag atttaggtgg taaagtatta gttgttacat
     1501 ttttgcctgc atttctagtc tataaacatt ggctacctca aagtactgta actgtggttt
     1561 ctgattttat gaataataac aatttcttga tgttctttat cacactacta gttgtcggca
     1621 gtattgcttc aatgaatcgg caaacattgg ttaaagcaac ttcacgtatt atcattattt
     1681 taattttatg cgatgtgatt ggttctttga taggaacagg tgtgggaata ctccttgggc
     1741 tatctgcttg gaatgcgtat ttctttatcg ttgcgccgat tatggctggt ggtgttgggg
     1801 aaggagcgat gccattatcg attggttatg cagcaatatt atctggtatg ggacaaaatg
     1861 atatctttgg gaagattcta ccgtgtgtga tgttgggaag tttagtcgca gttctactgt
     1921 ctggtatgct caaaaaaatt ggagagaaat acccacaatt aaatggtcag ggtaatttga
     1981 tcgatgggga tgatgaacat ttagagaact tgaagggttc agctaaacca gtcaatattg
     2041 aaaaaacatt gttagcaggc gtggtagcaa taacgattta ttttgttgct gtctatgttg
     2101 agcacttatt aaaatcactc cttggctttt ctattccttc acctgtgatc ttattagtct
     2161 ctcttatggg ggctaaaatg cttggtttta tccctaaaaa tatcgaagaa ggtggaaatt
     2221 cgttgtatgg attcactgtt cgtgggatca cacctccctt actttttggc gtaggggttg
     2281 caaaaacaga ttggttagag ctgatcgaag tatttaaaaa tcctgcaacg atagtaacaa
     2341 tcattgtgac ggtagtagct attgtcgcta cagcttttat cgccgcaaaa tttttaaaaa
     2401 tgtacccagt tgatactgcc atcgcagttt catgttgtag cggacaaggc ggtacaggtg
     2461 ctttagctat cttagctgcg ggtgatcgca tggaattaat gccatttgca caagttgctg
     2521 ttcgactagg gggtgctatg accgtaacgt tcgctatctt tttaatgggt ctgctatcat
     2581 aagaacataa agaaaggacg tgaccatgtg tttgatcaaa cagatatcca acgattattt
     2641 ttaaaaaata actatatcaa agaccaatgg gaaaatcttt tgcttgattc aggaatacaa
     2701 aagaagcaaa tcgaagattt tcaacattta gatcaaacat tgggtatata ccataaagaa
     2761 aagttagtag gaacagtatc ttatcaaaac aacgtgatta aatatatcgc cgtgtctgaa
     2821 aaatataaag atggtggaca tacatttaat gtactagtct ctgcaataat tcaggcaatg
     2881 agtcaacaag agatttttca ttatattgtt ttcacgaaac cgcgctatca aaaaagtttt
     2941 aactttttag gttttgaaac aatcgtatct accccaaaaa tagctgtatt agaaatggga
     3001 gatagttcta taaaacagta cctagagagg attcctaaag tgaatggtga aaaaaaagca
     3061 gcaattgtca tgaatgcgaa cccatttaca gaagggcatt attatttagt aaaacaagct
     3121 gccaataaca acgattgggt atatgtattt gtactcgaaa aagaacaaaa tcttttttcg
     3181 acgaaggacc gactcaaatt agttcaacaa ggattacaaa aactgaaaaa tgtcattgtt
     3241 ctatcaggtg gcgagtatat tattagccct gcaacgtttc ccacctattt tttacgagaa
     3301 gatgatgaaa tagcaaagga gcaaatggtc gtagatgcta ctttattcaa agaaagaatt
     3361 gccacttatt tagatatctc tgctagatat gtgggagaag aaccactttc cccaatgact
     3421 cgttcatata acgacatact ggaaacgatt ttaccccctg aaataaaagt tcatgtcctt
     3481 gcaaggaaga aaacggaaca acaccaagtt atttctgctt ctcaagttcg taaagcgtat
     3541 cttgctgggc aattggaaaa aataaaatat atggttccag aaacaaccta tcaatactta
     3601 aaaaataaaa gggagcgtta agtaatggaa ataaataaat cagcgattgc tggaacatta
     3661 gagtcaagtg atgtccaaat catgatttca ccgaatacag aaggaataga aatcgattta
     3721 gacagtcaag tgattgagca atttggaaaa caaatcaaaa aagttatcta tgacacacta
     3781 gcagtttatc agattaaaaa cgtaaaactc aaggtagtag ataaaggggc attagattgc
     3841 gttattgttg cacgattaaa aacagcgatc catcgttcct taggtatcca acaccaagaa
     3901 acaccgtggg aggtttaatt agatgatgaa agaacgtttg agaagaacaa tgatgtttgt
     3961 tccaggaaat aatccagcga tgatcaaaga tgcaggtatt tatggtgctg actcgattat
     4021 gttcgacctg gaagatgcag tgtctatggc agaaaaagac agcgcaagaa tgcttgtggc
     4081 tgaggcattg aaaacagtgg attatggtga cacagaatta attgttcgaa taaatgacct
     4141 gcactcagaa tttggacgtg cagacatttt tgcaatggtt aaagccggcg cgcatgtatt
     4201 acgtttacct aaaacagaaa cctctgaaga tataacagaa gtagaaaaag tgattataga
     4261 agcagaaaac tatcataatg ttccgatagg gcgaacattg atgatggcag ccattgaagg
     4321 tgcttctggt gtattgaacg cacctgcgat cgccaaagca tctgatcgat tgattggaat
     4381 cgccattggg gcagaagact atgtgacaaa tatgaaaacc aaacgatatc cagatggaaa
     4441 cgaattgttt tttgctcgca gtatgatcgt tcatgctgca cgtgcagcag gcatttccgc
     4501 atttgacact gtttactctg atgtggatga tatggaagga tttttaaacg aagtacgttt
     4561 aatccatcaa ttaggttttg atggaaaatc ttgtatcaat ccacggcaaa ttccagtagt
     4621 caatactgtt tatcagccgt caatcaaaga aatcaaacga tcactagaca tcatctcggc
     4681 aatcgaagaa gcaaaagaaa aaggttctgg cgtaatttct ttaaatggaa aaatgatcga
     4741 taaaccaatt gtagaacgtg cacaacggac attgatgtta gcaaaagcat cacgattgat
     4801 tgatgaggag ggaaatatcc atgcataata aacaaagacg tagcattcca tcaagtgttt
     4861 taacaaagta taaaaaagaa ttccaaagtg tttcattatc gccacaaacg attcaacgtt
     4921 gtgcaccaaa agtaacgact gtaactaatc agacaaataa attgatgcac tcgatcaaag
     4981 aagctataga aaaatcgggc ttaaaagatg gaatgacgat ttcatttcat catcatttga
     5041 gagaaggtga ttttgttttt aaccaagtga tggccgtgat ccgtgaaatg ggcatcaaag
     5101 aattgacctt agcaccaagt tctttaacga acactatgaa tgagatggtt attgaatgca
     5161 tcaaggacgg tacagtaact catatcacaa gcagtgggat gcgcggcagc ttaggtgaat
     5221 ttatttctca tggaggaatg gacaatcctg tgattttacg ttctcatggt aatcgtccac
     5281 gtgcaattga aagtggtgaa ttgaaaatcg atgttgcatt tctaggagta ccaacatctg
     5341 atgattatgg aaatgctaat gcgactgttg gaaaatccgt ttttggttca ttagggtatg
     5401 caaaagtaga tgcacaatat gcagataaag tcattcttct aactgatcat ttagttcctt
     5461 accctaatac gcccattagt attccgcaaa cacaagtcga ctatgtcgtg gaagtagaag
     5521 caattggtga tccgaataaa atcggtgctg gtgctacacg gtttactaaa aacccaaaag
     5581 aattaaaaat tgctgaaatg gtcaaagatg tcattgttca ctcaccttat ttcaaagatg
     5641 gcttttcttt tcaaacagga acgggtggtg cagctttagc agtaacgcgt tacttagcta
     5701 gtgaaatgga agaaaaacag atcaaagctt cttttgcatt aggtggcatc actaaaccaa
     5761 cggttgattt attggaaaaa ggtcttgttg aaaaagtgtt agatgtccaa gactttgaca
     5821 aaggagcagc tgaaggaatg gcgcggcttg agaaccaaca ggagatcgat gcttcctttt
     5881 atgctgatcc aagtaataaa ggagcggttg ttaaccaatt agatgtcgct attttatctg
     5941 cattagaaat tgacacaaac ttcaatgtaa atgttatgac tggttcagat ggtgtgctaa
     6001 gaggtgcgat tggtggacat caagatgcag caacggctaa acttactatc atctcagcgc
     6061 cgttagtacg tggccgaata cctacagtag taaatgatgt tactacattg atcacaccag
     6121 ggaaaagtat cgatgtatta gtcacagaag taggggttgc tatcaatccc caacgtaaag
     6181 atctaatagc tatttttgaa agaattccac aaattcctgt ttttacaata gaagaattac
     6241 agcaaaaagc agaaaaaata gtaggcatcc cggaaccttt gcaattcaca gatcggatag
     6301 ttgcctatgt agaataccga gatggttcaa ttttagatgt cgttcgtcag gtgaaagaat
     6361 ttgaagaaga gagatcatga tgtttgatac tggagaaatt caagaaatcg aggatatttt
     6421 gatccataaa gaacaacgtg ctaacttgca aagcaacctg ctttccaagt attcaaatag
     6481 ttcattgatg gtctttacat tgaatattcc tgggccgatc aaaaataatc caatgattga
     6541 gcaggtattt cgtcagggac agcagtcaat tcagcaaatg tttttaaaaa aaaaggtgga
     6601 aatgacgtac acaaaagaaa tcaatttgcc aagtggattg gactggtacg taatagtaac
     6661 agaagcacct ttgaatctca aaaaatggtt ggtcacgtta gaagagcaag acgcattagg
     6721 tagacttttt gatttagatg tcttgttcaa aaaaggagag cagataacaa ttgtcagtcg
     6781 ccaagctctt aatcatgggg aacgtccttg ttttatttgt gggaaatcag caaaggtatg
     6841 tgcacgtaat cgtacacata ctgtgaaaga aatgcaaaag aaaatcgaac aaatagtagc
     6901 cgattcctta aaaggagcat tgaaacatgc atgataatat tcaaaaaata gcacaagaag
     6961 cacaattagc gatgctttat gaagttacat gtatcaataa accaggattg gttgatccag
     7021 tagaccccgg gtctcatcaa gatatggaca tttttacttt tctacaaagt agtgtagttt
     7081 tgactcccta ttttgaagaa tttatccaaa caggattgga ccgacaacat caaccaattg
     7141 aagaaacctt tatggcgatt cgacagattg gtttagaggc tgaaactgcg atgttctcag
     7201 tgacaaatgg tataaataca cataaaggtg ctatcttttc attggggatt tttcttgcta
     7261 tttgtggccg gttaactatt tggaaagttc cttgtaaaaa aagtttcttt caaaaagaaa
     7321 ttcaaaaaat gacgaaaaat ctacttaacg attttgggaa gattgatcaa acaaaaccaa
     7381 aagcatggac ttggggagaa tatctatttg ttaaccatgg attgacaggg atacgagggg
     7441 aagccaaaag aggttatcct tgtgtttttg accgaggatt gccttattat caagcatatc
     7501 aagggtcgca acaagataag atgatagaca ctttactttt tctatcaatg gaagtagaag
     7561 ataccaattt gatcaaacga agtaataata gacatgtttt tgaagagtat caattactta
     7621 ttcgtcctta ttttgaatta gggggtgtaa aaaccataca aggtaaaaaa tatttggatt
     7681 acctaaatca gcaatttaaa aagaaaaatt ggagtattgg tggaagtgca gacttattga
     7741 tccttacaat ctttttagat aaaatcatgg acaaaggatg gttatgttga tactataata
     7801 cattattttg tattagtaag ctaataacta aaaaatggtt caatacaaat attttataaa
     7861 aaatggtagt gcctatcctt tcagattgta gacaaagaaa aatttctttg tctacaattt
     7921 ttttgttaat gacttcagtc agtttcgtgc gcaaagcgtg cgaaacaaga aaaccatgcg
     7981 tttctacacg tggaagaact agcatatcga aaggagtttt ttcatgtcaa atgacgataa
     8041 aagtttagcc catactcgtt ggaattttaa gtatcatatt gtatttacac caaaatatcg
     8101 acgaaaagta atctataggc aattacgaaa agatattgga aaaatactta ggaagttgtg
     8161 caaaataaaa aacgtggaaa ttatagaagc acatgcaacg ccagatcata ttcacatgct
     8221 tgttcaagta ccatcaaaaa taagtatatc cagttttata gttatctgaa agatcgtagt
     8281 gctgtgctaa tccacgagca gcacgtaaat cacaaatata gatacggaaa taaatcattt
     8341 tggtcggagg aatattatgt gagtacagtc gaattgaatc aaaagacaat tgaaaaatac
     8401 atccgtgaac aagaagctga tgatcgcatt tgagatagta taagtaaaag agagtagatg
     8461 ttgcaataac aaaagggtaa aaatggacta cctccagtaa aataccgaaa aatagtttaa
     8521 cttttggaga taagtccatt taagggtcta tagaatgaca atttttttag gggattttac
     8581 tattattact tcaagacccg cttggattcg caaagtgagt gaactcttaa aactacctga
     8641 tagtaggttg ttttaagagt tatctgaaag taaaaattgc atttatattt ttgataaata
     8701 cgtaaattta tatatacgta tttatcaaag ttttaggcca aaggaatatt gtgtaaatac
     8761 actaggattg aatgaataga ccagaagaaa ttgcgtccaa gaacaaaaga agcatgatag
     8821 tgctctatat aaattgggca ttcaagaatc tgaaatttaa aggtagaatt ttagttagac
     8881 ttttagattt taaacacaaa aataaccata caagcaacaa gaagcaaagt gctatattat
     8941 aaattgtccg tccgtttact tacataagat cattggggct atttttaaaa gagaataata
     9001 gataataaat gaaaaaaaag tcaagtccac aatcctgtgt aaaatactat acaatgctct
     9061 cactattttt tacttggcaa atttaatata ttttcttgat gaagaaagcc actcatcgtg
     9121 ttgatcaata aggactgctc caattaaacg attggctgaa acgcagtttg gaaagatacg
     9181 aataattttt tctcttctgc g
//
LOCUS       DAFEIE010000085         8969 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFEIE010000085
VERSION     DAFEIE010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.088"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(57..350)
                     /locus_tag="LP345_002484"
     CDS             complement(57..350)
                     /locus_tag="LP345_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBL1761241.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(378..1043)
                     /locus_tag="LP345_002485"
     CDS             complement(378..1043)
                     /locus_tag="LP345_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBL1761242.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1183..1815)
                     /locus_tag="LP345_002486"
     CDS             complement(1183..1815)
                     /locus_tag="LP345_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1761243.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1822..2889)
                     /locus_tag="LP345_002487"
     CDS             complement(1822..2889)
                     /locus_tag="LP345_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1761244.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2886..3617)
                     /locus_tag="LP345_002488"
     CDS             complement(2886..3617)
                     /locus_tag="LP345_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBL1761245.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3786..4265)
                     /gene="greA"
                     /locus_tag="LP345_002489"
     CDS             complement(3786..4265)
                     /gene="greA"
                     /locus_tag="LP345_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBL1761246.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="LP345_002490"
     CDS             complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="LP345_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBL1761247.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5780..6949
                     /locus_tag="LP345_002491"
     CDS             5780..6949
                     /locus_tag="LP345_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL1761248.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7216..8850)
                     /locus_tag="LP345_002492"
     CDS             complement(7216..8850)
                     /locus_tag="LP345_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761249.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2856 a         1701 c         1333 g         3079 t
ORIGIN      
        1 aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct ctttttttat
       61 tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac aagtaaatca
      121 tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc atcaatttcc
      181 actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa accatcatga
      241 acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc tggcagatca
      301 atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat cccaacaacc
      361 tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac atcgcctgtc
      421 tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc aggagaagcg
      481 ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg ttgcctgaaa
      541 tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat ttctgctaaa
      601 gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa attatgcgca
      661 atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat cttttcaagt
      721 actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc catttccttt
      781 accatcagag taactaagat actggcttga atatcttctc caatagcgac aattacatga
      841 tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt tgccacaaca
      901 gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc aatagccagt
      961 acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg tccaagacct
     1021 acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt ctcagtataa
     1081 caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa gaaaaataat
     1141 agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca ccaaaccatg
     1201 tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag ccaatatatt
     1261 ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta tttcctgatt
     1321 actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta gttcttcatg
     1381 taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca cttctggttc
     1441 taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat gtgcggtaga
     1501 ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt tttcgtcatc
     1561 aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga ttgcttttgt
     1621 tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt ccggtcgaag
     1681 tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta cttcaatgtc
     1741 ttcttgaata gataaataag aagagacgcc taagcgcacc atttcatggt catctactaa
     1801 taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga tttctacact
     1861 tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag ctactcgttc
     1921 tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa accctgttcc
     1981 gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata cctctaattc
     2041 attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc ggaacaagtg
     2101 atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg aaatctggat
     2161 tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt tctcttctaa
     2221 attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag cgttgatgat
     2281 ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt tttctgcttg
     2341 ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa ctgaatcatg
     2401 cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg tttgtccatc
     2461 tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa tcattttttc
     2521 ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg atgcacttgg
     2581 gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac gcagcttttc
     2641 ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga caattaatcc
     2701 tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata aacgtgcacg
     2761 cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga aaagtgaaaa
     2821 tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc tggatatttt
     2881 tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat aatcttcaat
     2941 ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt tttcaaagaa
     3001 aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa tcggatggct
     3061 acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat cacaatatta
     3121 tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga aatgacggcg
     3181 atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc gaataattgc
     3241 tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat catgatctgt
     3301 ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac acctttcaga
     3361 ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt gactaagcta
     3421 aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt acgaggatgt
     3481 ttgcgcatag ctagatatat attgaaaata ccgaatatca ctaaaagcaa aagtccagta
     3541 ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac cacaaaaaaa
     3601 cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc atcataccta
     3661 tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa atctaaaata
     3721 cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta gatctttcag
     3781 tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc tggagtagca
     3841 atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg agaatcattg
     3901 gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta ctcttcttct
     3961 tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc atctgcatct
     4021 acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt tgtgattctt
     4081 ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc ggaaagatct
     4141 ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac tgtttttagt
     4201 tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata aactttctct
     4261 accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct tttgaggaat
     4321 atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct aaaaatgatc
     4381 aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa ttccatatgt
     4441 tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac gaaataataa
     4501 tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg attgtcaaaa
     4561 ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac agctgtatct
     4621 tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat atctgactga
     4681 agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt acgatcattt
     4741 tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg tacagtcaaa
     4801 tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt gttcaccatt
     4861 tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc tgggaataag
     4921 taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa cagttctggg
     4981 aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa aaattctttc
     5041 ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc gtacccttct
     5101 ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc ttcttgcaac
     5161 tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc agcttgaaag
     5221 ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt aataatattg
     5281 tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat ctcgacttgg
     5341 actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata acgatacacg
     5401 gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa aatgatcttc
     5461 ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat atctgctgta
     5521 gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc tgacaaaaca
     5581 actcctcctt actatcaagt tcgtaacttt attcattata catgatattt gaattggcgt
     5641 gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaatccatt actataagat
     5701 taaaataaat gttatcaaga tacaagctat tttagcttta ttctttctgt aaaaaagaaa
     5761 ggagactaaa taaactatta tgaaaaaagg aaaacatgct aaaaaaagaa aatattcatt
     5821 tttaatgatc gttgtcgtgt tgtttagcct tagtgcgttc tctacaggaa ctattcttgg
     5881 atggcaattt tacaataatg aacactctca gatagttgcc catgctcaat cagctcaaaa
     5941 aaagttgata ctgactacca atgaacaaca gctcgttgaa aaaatcgatc aactattaag
     6001 aaaaaatgat tatattggct caatttacgt aaagaaaaat aatcgcatca tcatggaaaa
     6061 aggctatggc tatgcgaata aactcacgca acaaccaaat gatccttctc tttattatca
     6121 gattggttcg gttcaaaaag cattgactac tcttttgatt ttaaaacaag tcgagcgtgg
     6181 gcacctttct ttagatacta agctggctca attctatcca caaattgctg gcagccagca
     6241 aattactatc cgtgacttgc tgtatatgcg ctcaggcttg caccgaactg cttctccaac
     6301 cataccgatg actgatgaag aagtcgttca atttgcgatt cagcacttaa aatttacaga
     6361 ttatcagacc tctcattatg attcattgaa ctttaccata ttgactggaa ttttgatcaa
     6421 attaacaaat caaccgtatg aaaaattatt gaccgatgat atcatcgaac ctttaggatt
     6481 acagcataca aaattttatg accaagtcaa aaattcatcc aatcatgcac tatcctatca
     6541 aatgtctaaa gaggatgatt actttaaacc actgacagaa tctgaaacag agatccataa
     6601 cgaattaggg actggtaata tcagtatgtc cgtctatgat ttaaatacgc tgtttacaca
     6661 agttttatct ggaaaactag tttccaaaga cttactcttc tcattatggc gtgaaaatgc
     6721 gaatggacat ccatatagtg gtggggtata tagcggagat aattatatcc tgtcgcaagg
     6781 aaatatcgac tcttttgata catctgctat atttagcaaa gattcacagg atgctatcat
     6841 catggaaagc aatataaaag ctgacaaaac tatcaaactg cctactgctg atctaagaaa
     6901 ccaaatctat gacctgatgg aaggaactac taagttggca aatagctgat atgatgaaaa
     6961 gatagcaaat actacttctt tgaatagcat ttgcttaaaa aaagtactcg actaaacgta
     7021 ggaaagagtg tgggacaaat ctaaaaatca atttttgcta cagactttaa ttccaaataa
     7081 acagaacaga aagaggtgtt cttctttctg ttctgtccaa attattctaa gatttctctt
     7141 taccaacatt atttgacaaa gggcctatta aatctaaaat agtatcttta gattgctaaa
     7201 atatgtgcta gcaaatcatt catggcttgt tcttattttt aattttatgc aataaaaaag
     7261 aagaacaatt agcgtgatta tagaaataaa taatgagatt ttagaaaaaa atgtgtatga
     7321 atacctgatt gttactttat ttattccact ttcacttttt actgtaacaa aaggacctcc
     7381 ttgttttagt actgtagcat tttttgaatt aacagtaacc gttaatcctt tataccggaa
     7441 tacaggtaaa actattgttt tgccttttga agatttaagc gtaaatgtaa tttcatcttt
     7501 atttggagaa aagctactat aaataacttg accatcttct gtaacttgat ggtttttcaa
     7561 aagcaattga tcttttttat agcctatagg tacataatca aaattctcaa attcttcaag
     7621 tttattttcc atttgttcat tagaataagt tccttgaaaa ttcatttctt tcaccatgtt
     7681 aactactgat gaataattta aaattgaaat agctaatatt aataatagta taaaatttct
     7741 tctccttgta taagaaaatt tttccaactg tggagaaata aatagagata ctgaaaaaga
     7801 tatgaacaat gttgaaaata tcataaaacg ccaaggagct tgaataatat ttaaaggagt
     7861 attttgtaag gcaaaccatg gaaatatttt tgtacaaagt agaatagata ttatacccat
     7921 tatataagtg attttagata agattcctaa ttttttaaag ttaaatgtta gtataattaa
     7981 acaaataagc aaagttaagc caataccaaa tgatagtaat tctgaatcta tacttccaat
     8041 caaaaactct ttacccagat aaattgctct tttttgtaat atatccacat aaggtctatt
     8101 cagatcttga tacaatgtct gctcaatcat aggacctata aacgctagtg aaagaagtaa
     8161 agtaactata gcagctttta ttaatttaat aattaagaag atttctattt tctttttccg
     8221 ataaaattga ataattaaag caattataat cattaccata gtcatagcta cagaaagaac
     8281 atgagtgtaa attaataaag tcatgctaat cgccaacata acccaagatt ctttttttga
     8341 gtcgtaaagc tttataaacc cgagtaaaat aagaggaagt attgacattg cgagtaattc
     8401 ccccattgcc cctcgaagaa atatttctac actcctaaaa gaagatgttg tatatataat
     8461 agcgaaaaag gagctagtaa catgtttttt ggtaatttca tacattacat aatgacatat
     8521 aaatagagta atgagcgtaa caatataaag aaaaaggtta tagcctattg ctaaattagt
     8581 aaacttgatc aataaaaata aaggatatag agttaaccat gggtaaaaat tatttacttg
     8641 catgccatat gatctaaacg tttcaaaatt aataggggag ctaaaaatag attctaaact
     8701 taacgcacga ttaatgtgaa atgccgtatc ataaaagcca aatatttcca tgtttttaaa
     8761 tgctggaaat aaatataata aactaacaaa tgcataaact ataaatattt ttacagaaaa
     8821 aatttttttc aaattcatat accacctcat gtttttttat attacatata gtatcattta
     8881 tttttttaaa acactagatt agtcactata taaaatgtga ttaattttat tattaataaa
     8941 atatttttta tattacaaaa gtagtgttt
//
LOCUS       DAFEIE010000086         8732 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFEIE010000086
VERSION     DAFEIE010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.089"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            2..74
                     /locus_tag="LP345_002493"
     tRNA            2..74
                     /locus_tag="LP345_002493"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="LP345_002494"
     tRNA            78..150
                     /locus_tag="LP345_002494"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="LP345_002495"
     tRNA            155..225
                     /locus_tag="LP345_002495"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="LP345_002496"
     tRNA            238..311
                     /locus_tag="LP345_002496"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="LP345_002497"
     tRNA            323..394
                     /locus_tag="LP345_002497"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="LP345_002498"
     CDS             660..1853
                     /locus_tag="LP345_002498"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBL1761250.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="LP345_002499"
     CDS             1983..3455
                     /locus_tag="LP345_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1761251.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="LP345_002500"
     CDS             3538..4326
                     /locus_tag="LP345_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBL1761252.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="LP345_002501"
     CDS             complement(4393..5061)
                     /locus_tag="LP345_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBL1761253.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="LP345_002502"
     CDS             5176..6888
                     /locus_tag="LP345_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1761254.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="LP345_002503"
     CDS             6891..8663
                     /locus_tag="LP345_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1761255.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2622 a         1487 c         1945 g         2678 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc ag
//
LOCUS       DAFEIE010000087         8654 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFEIE010000087
VERSION     DAFEIE010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.090"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="LP345_002504"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="LP345_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBL1761256.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /locus_tag="LP345_002505"
     CDS             complement(738..1460)
                     /locus_tag="LP345_002505"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBL1761257.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /locus_tag="LP345_002506"
     CDS             complement(1596..2477)
                     /locus_tag="LP345_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBL1761258.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="LP345_002507"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="LP345_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBL1761259.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="LP345_002508"
     CDS             3717..4196
                     /locus_tag="LP345_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBL1761260.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="LP345_002509"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="LP345_002509"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBL1761261.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="LP345_002510"
     CDS             5497..5625
                     /locus_tag="LP345_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL1761262.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5629..6174
                     /locus_tag="LP345_002511"
     CDS             5629..6174
                     /locus_tag="LP345_002511"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL1761263.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6628..8319)
                     /locus_tag="LP345_002512"
     CDS             complement(6628..8319)
                     /locus_tag="LP345_002512"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBL1761264.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
BASE COUNT         2403 a         1771 c         1568 g         2912 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaaccca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
     6481 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
     6541 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
     6601 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
     6661 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
     6721 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
     6781 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
     6841 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
     6901 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
     6961 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
     7021 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
     7081 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
     7141 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
     7201 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
     7261 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
     7321 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
     7381 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
     7441 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
     7501 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
     7561 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
     7621 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
     7681 agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga attggacgta
     7741 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
     7801 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
     7861 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
     7921 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
     7981 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta ctgtttgcaa
     8041 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
     8101 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
     8161 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
     8221 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
     8281 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
     8341 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
     8401 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
     8461 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
     8521 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
     8581 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
     8641 tagtcgtttc ataa
//
LOCUS       DAFEIE010000088         8613 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFEIE010000088
VERSION     DAFEIE010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.091"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(613..930)
                     /locus_tag="LP345_002513"
     CDS             complement(613..930)
                     /locus_tag="LP345_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1761265.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(931..1185)
                     /locus_tag="LP345_002514"
     CDS             complement(931..1185)
                     /locus_tag="LP345_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1761266.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEDNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            1544..1948
                     /gene="tnpA"
                     /locus_tag="LP345_002515"
     CDS             1544..1948
                     /gene="tnpA"
                     /locus_tag="LP345_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBL1761267.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            1965..3113
                     /locus_tag="LP345_002516"
     CDS             1965..3113
                     /locus_tag="LP345_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1761268.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTIALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(3336..3554)
                     /locus_tag="LP345_002517"
                     /pseudo
     CDS             complement(3336..3554)
                     /locus_tag="LP345_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(3820..4014)
                     /locus_tag="LP345_002518"
     CDS             complement(3820..4014)
                     /locus_tag="LP345_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761269.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(4114..4200)
                     /locus_tag="LP345_002519"
                     /pseudo
     CDS             complement(4114..4200)
                     /locus_tag="LP345_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            5366..6406
                     /locus_tag="LP345_002520"
     CDS             5366..6406
                     /locus_tag="LP345_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1761270.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            7230..7562
                     /locus_tag="LP345_002521"
     CDS             7230..7562
                     /locus_tag="LP345_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBL1761271.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            8181..8522
                     /locus_tag="LP345_002522"
     CDS             8181..8522
                     /locus_tag="LP345_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBL1761272.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         3053 a         1301 c         1437 g         2822 t
ORIGIN      
        1 aatatatttt ttaccagcaa accatacata tcttttttca ttaagtatgt tcactatctc
       61 tcctccatta attatattta gcatcaaata gttattgtac ctatatttta tcccattcct
      121 tttaaaacaa gaatacgtac aaagtaaaat gttgtaaata gtctagcagg gaagtatatt
      181 ttcatgtacc aacataatat ttaagaagtt tcccatagat atattggact tcctctttta
      241 aaacacaaaa ataaatacta ccttatttag gtagtattta ttaaaagtta cgtcaatttt
      301 gattaaaaat atactacttg aacctctcat gagtaaagtc acgaaatttt tgggaataga
      361 gcgtacttga tatcttattt tttcactaat agcagtgtct cttattcacc aagcgatccc
      421 cgtagttcct aaggttctta atttttctct agactaatga ttgtatcttt agaccttcgg
      481 ccataacatg gagcaaaata aaaaggtact aagtcttata tatcaatctt cgagtaaccg
      541 acggttaaca accatatcga gcggcattaa tcacccacct gtagaggatg agcgactttt
      601 tcctaattat tgttaaaagc ctagtttcat ttgtttagat tggaaaatac gtcctacaag
      661 tatctctttt ttttcatggt cgatccgata aaataaggca tagcttttgc cgatcacgat
      721 ccgatatgtt gggatatcca ttccatagat ttcggaaact tcctcatgca tagttggaaa
      781 atttttggtt agttctaaag ccttctggat cgcacctaca aatcttttta tgctggctgg
      841 agaaagagca agctcatttt cccattcttc tattatcgtt tcaaggctgg tctgaaaact
      901 tttagaataa actagcgtgt actctttcat ctattcactc cagccgtatt ttccgaaagc
      961 ttttaccatt tcaatttctg aaactgttaa acctttctca aagtcttgga aactttcttc
     1021 aatcaatttg cgatcgtgtt cttttgctat ttgagtagta tctaatatga ataagttgtc
     1081 ttcttgtttg gcttggataa tgtctccgct ttttaatcca agagagcttg gaaggatcac
     1141 tcccacgcta ttgccgatct ttctaacctt tagttctttt cccatgttat cacactcctt
     1201 ttagtttttg atgaataaat tataacatgt tataacaaca attgccaacg gtgtttctta
     1261 agggattcca ctccatatta ttattggaca aaataagcca cttagaacgc tgaaaacata
     1321 tacaaacgat atcaaaatac gagtgaacta ctcaccatac acttccgtta acatccattt
     1381 aacagaatta ggcagaagtc gcccatcctc tataggtggg tgatgaatgc cgttcggtat
     1441 gagggttacc gttggtaact cgaagaccga caactaaggc gtattgcctt tttattttgt
     1501 cccatgttac aatcagtcta tacaagaaat gagttgatat aacatggaat tagatacaaa
     1561 taatcattca gtatttcttc tttattacca ccttgtttta gtaacgaaat atcgtagaca
     1621 agtgattgat gatgaaatat ctgattatgc caaaactact tttgaaagaa tttcagaatc
     1681 gtatcacatt actttagtgg agtggaatca tgataaagac cacgttcata ttatgttcaa
     1741 agctcaacct aaaacagaat tgacaaaatt catcaatgcc tataaaagtg ccagctcaag
     1801 attgataaaa cgtgactttc caagagtcaa acaatttctt tggaaagaaa tgttctggtc
     1861 taaaagcttt tgtcttctga caactggtgg cgcaccaatt gatgtgatta agaagtatat
     1921 ccaaaatcaa ggaaacaatc ataaatagaa agtaggtgaa ctttatggaa caactaaaag
     1981 catacaaatt cagaatctat ccaacagagg aacaagaaat cttctttgcc aaatcttttg
     2041 gttgtgtccg taaggtctac aatctaatgc ttgatgaccg aaaaaaggcg tatgaagaag
     2101 ttaaaaatga ttcttctaaa aaaatgactt ttccgacacc agctaaatac aagaaagaat
     2161 ttccgttttt gaaagaaatt gatagccttg ctttagccaa tgcccaactt aatttagata
     2221 aagcatacaa gaattttttt cgggataaat ccgttggatt tccacgtttc aaaagtaaga
     2281 aaaatcctgt tcagagttat acaacgaata atcaaaatgg tacaattgct ttgattgata
     2341 gtaaattcat caaagttcct aaattgaagt cattagtaag aattaagctt catagacaac
     2401 caaaagggat tatcaaatct gctacaatat cacgtcattc tagcggtaaa tactatattt
     2461 ctttgttgtg taaagaagaa attatcgaat tacctaaaac taattccaca attggtattg
     2521 acttaggtat tatggacttt gcgattcttt ctgatggaca aaaaattgat aataataaat
     2581 tcacgtccaa aatggaaaag aaactaaagc gtgaacaacg caaattgtct aggcgtgctt
     2641 tattggctaa aaataaaggt accaatctat ttgaagctaa aaattatcaa aaacaaaaac
     2701 gcaaagtagc tagattgcat gaaaaagtaa tgaatcaacg tactgatttt ctgaataagt
     2761 tgagtacaga aatgatcaaa aatcacgata ttatctgtat tgaagactta aacacaaaag
     2821 gtatgttgcg aaatcataaa ttagctaaaa gtatttctga tgtttcttgg tcaaagtttg
     2881 tgactaaatt acaatacaag gctgactggt atggacgaaa aatcatcaaa gtagataaat
     2941 ggtttccgtc tagtcagatt tgttcagagt gcggacataa agatggcaag aaatctcttg
     3001 aaattcgaga atggacttgt cctgtttgtc atactcatca tgatcgtgat atcaatgcta
     3061 gtatcaatat tctgaccgaa ggtctaagac tacattctat gggattggct tagatccaat
     3121 catcaagaac cgtaggaact acggggatag cttggtaaat aagagacacc gctgttagta
     3181 aagaaatacg ctatcaagta tgctctattc ccaagaagct cccacttcaa gcgttaagaa
     3241 ccgtcaggtt tagctaagtg gtgagtagtt cacgtaggta tttttattat atatagattt
     3301 aacatatgtc ggtcggttga ttgatatagc taaagttata actcaaccga agccgattca
     3361 tctacacgaa taaagttgcg agtgttctcg gctaattcat aaaaattgtt atgtgttcca
     3421 tatagcaata ctggaataac tttattttct tgaatctcat aagcaactct atacacggtg
     3481 accgcatact taaatccatt agaccaatta cctgataaac ctccagtttt ttgctcttac
     3541 ttaaatggat caatggcaat ttcatcacaa acctatagag gatgagtgac ttctgcctaa
     3601 ttacgttaaa aaatattgaa agtaactcta tgtagcaaaa aatatctaga atttcatttc
     3661 ctcaaaactg atcgatattg tatctaaaaa tatatactac ctaaaatagg tagtatatat
     3721 taaaatatgt gcttttgtta gaaaaatcaa tacataaatt atcatatctg tatatgtcat
     3781 ttaggtattt cagttatgtt ataatagttt tgctgtctgc taccccggcc taatctggca
     3841 aggggaggag gagatataat gaaatacctt tttgattttg tttttgcaat caagccactt
     3901 gcagatgtag tgtgcagtta cctctgcaaa tggcttgatt gcaaaattgc caaaaaagac
     3961 agtaagccta cccgttaatt ctataatata gaaacgtaaa aaaaacccca tcagcctgca
     4021 cgctgatggg gtttggtgat ataatgaaat acctctttgt tactcataat tgtaccataa
     4081 ttagtcacga atgcaaccaa tagaaaaaac tacttagaac ggtagatcat cgctaataac
     4141 aatgcattgt ccaccaaatg gattttgtga agcattaaat acattgttat taattgtcgc
     4201 tgcttttaac taggcctctc cccttctatt ataaaagaag atatatatca tttcttaatt
     4261 acctactacc ttaaaccaaa atttaagtac tacctaattt aagtattact taaacaatct
     4321 aaaaaatagt tatcccaatt gttatgcttt tataatacga ttatttgtaa caaaatgaat
     4381 attatataat taaacactac catatttagg tagtgtttaa ttattagcaa aacaaaaaat
     4441 atttattcta ttctcttaac ttcaactaag ttatgctgca cacctttata taaatcatat
     4501 gcaactcatt agctagacaa actacaagca tgtagtttta tctgttaatt atgtactacc
     4561 taaataaagt agtttataat tagcaagtat atatatttaa aaatttaaga ttaatttttt
     4621 tatgacttgt acaaatttat ctgatattct cttattaaga actacctaat ttgggtagtt
     4681 cttatttttt acattttaag tagtatttaa ttgcaatttg gtagtatttt tttattatct
     4741 tattcttaga acggtagtac ttaatataaa tataggtagt atctaattta agtattaatg
     4801 gtagtatcta aattaacagg tagtatgtaa ctactttaaa gtaatttttt tcagattaac
     4861 acagtagtat cttattaaat aagttaattt taatggtagt acataattat tatatatatc
     4921 tgacattggt agtacttatt gtatttttta gtagtatata atctattgtt ttctagccta
     4981 aagccttgtc ttataagaat aatataatat atactactga aataaggtag tatatattac
     5041 tagtaatggt agtatgtttt atatgcataa ggtagttctt aatttatttt ttgttttgac
     5101 actggtagta cttaattatc tttaatttta aaactaaatt ttattcatac gtttttctgg
     5161 tagtatttaa ttataaataa tatttattta aagtagttct taatgacttt aaaggtagta
     5221 cataattcat tttatttctg attttaggta gtatttaatt aaaaaacagt tttaatgcgt
     5281 ttgcattttt tatttatctt tgctattttc gaaaagagta ggtaatttta cataaataaa
     5341 acaacgtgaa agtagaggat ctacaatgac tgattttaaa ttttttaagg cggatagagt
     5401 ttacaacgaa ttattttatc aatttccaaa agtctttatt gtttctgacg aatacaaaaa
     5461 aatgaaagat tcaactaaga ttgcctatat gcttttaaaa gcaagattag agatcgcaat
     5521 cagcaaacgg caaatcgatg aagaaggtaa tgtttatttt acttatacga caaatgaact
     5581 atgtagagta ttaaactgcc aaaaacaaaa agcgatagca atcaaaaaag agttggaatc
     5641 ctttggttta ttattacaaa agcagatggg atttaacaaa cagttaggga aaaataatcc
     5701 taatagacta tatctagcag aattaaaagt ctcagaaaat gatatctact tactcgaaaa
     5761 atttgataga gagaataggg aaaacgttga taaatcagag ggtatgaaaa tcatacccac
     5821 cctcgacgaa aaatcagacg ctgaatccct tggggctcaa gagggtatga aaatcatacc
     5881 gtgccaaaac gttgataaat cagagggtat gaaaatcata ccagaactta ataataatat
     5941 attagacact aatagacaca atatagacac tgaaaaagac cgcctacaag atcaattgtt
     6001 gttagacaat tttgagacaa ttatgacaaa cgacagcatt gctacgtttg tccctgaacg
     6061 agtattaaat ttgataaaaa cattttcttc aagttacagt gaagctcaaa aaaccgtcca
     6121 gactattcat aatgcaaaga aaaaagctga aatagaaagt ggtatttcga tagtttttga
     6181 agaactcgat agttattatg tcaatgcaga acaagaatta tacacgacac tgttaaaagc
     6241 ctatcaaaaa ttaaaaaccg aaaaagtcga aaatatccag aacctgattt ttgtctatgt
     6301 aaaaaattgg tttatcgaaa aaccaatagc tgctaaagta tcaagtgaaa aacgtttgaa
     6361 ttatgaaagc tccccaagca ctattacgaa agactggtta gagtgaaact ttactgacaa
     6421 agtgattgtt gcttcatgga gtaacattaa aattaaaaat tttttattat tctaattata
     6481 ttacgaatat tacaaaataa tagctatttt aatagaattt ataagttaaa atattatgat
     6541 aaaaatcaca aacgtagcct tttacgtcat aagtgttaaa agaaataatt aatttcaaat
     6601 atagaaaagg gaacgtatgt ttgcatactc cttttttttg agttataata atacgcgaag
     6661 agagataatt tcattattta aacaagctaa aaatcttgat attacttctt ttcaggcaat
     6721 acgaatatta ttcgcttaca ttttttgtat aaatttaatt gtctgctatg cttgtgatga
     6781 attgattttc gttctgcact tttggatgat aaatttggac aattgaaaat acaaaaaaaa
     6841 gaaaggcggt atgaactcgg aaggctggta accttcgtca gcgttcatac acggcattaa
     6901 gatttggccc ttaatgcgtt aacctttcag tgttacggta ttacccgcaa tggatttagt
     6961 ataacagata ttcaaaagtg ataccacttt ttttggctgt gttaaggtta aaaatacgtg
     7021 atattacgat gaatctatgc ctaagcacaa tgttataaaa atgtccgtgt ggctctttgc
     7081 cgtatgacga acgctgaaat tagagggaac gcatgtttgg atgcgttccc tcttttttgt
     7141 ttgtcatgaa cgaaaatcaa ttctctattt ttgaaaaata acaagaaaaa cttgttaaaa
     7201 atatttaaag aaattgggtg gtttatttta tgtcatatac aggaattttg agtctcaaag
     7261 atatttgtca ctacggtaaa cggtgtaccg ctacagagaa aatcacgaag aaactatcaa
     7321 ctggccaaag taaaaccgtt gtgcagtgta agaaatatat aatccagaaa gacaaagtct
     7381 cagaggaaat gatttattac attgggaaac aaaagcaaat aattttaaaa gatcctatcc
     7441 ccttaaaaga gctatatcca acaatcaaac atgtttatga ccaaaacggt gtactgattg
     7501 gtcgaagaaa aaatggagtc ttgcgttgta ccgcaaaagg gatggggcgt ttgatcggct
     7561 gaattgatca ttctcataac ttgtatttta tcgtttttcg cttgcttgaa aatattgtcg
     7621 agacttctaa aggaacttag agtcactaga aaaataagga gtagacttga tctatcaaca
     7681 attcccttcg gggagtgacg gggtaggttt taacgattgg taacgtaaaa aattggtcaa
     7741 tcgagtaaat gcgcttgttt ggatagtggt gaaatgaatt tgtgtaaata ataagcgcag
     7801 agtaaacaag agggaattta gaagttagac aagttagaat agcgtctaga ttaatcatga
     7861 gcagctacta agggatctag actttgacgc aaactcatgg aataaggagt aggtcttctc
     7921 gtaatgggga ggacgcacaa gaaattgtgt cgtgtgctgc agtacatgta gatacttgcg
     7981 aggacgttga ttattggatc aatcgagcat ttaccgctgt ctactagggt ttctcgtttc
     8041 ggacgccata aacgagtcga aattttttat gtatttttaa gtaaacgaaa aacgataaaa
     8101 tatgaacaag tcctgaataa agtgaaaaaa ttgatataaa acatagagaa aatgaaattt
     8161 acgtaatgga ggaatgacaa atgaaaaatt atgatccgaa tatacgattg ggcacacata
     8221 ctattaaggt ttctttccaa cgttgggatt acaaaggatt tgtgacgttt agaagaggcg
     8281 gaaattgtaa aggattagat gttttagcat tagacgagga tgatttatac gatcaaacat
     8341 tgactgataa tccaattgga ttcggcttgc tacctgaaga tgatgaaggt aatgaatggt
     8401 ttaaaatgac gcttatgaat gataatggag acgaattatc tgttgaagat acttggtcat
     8461 atttgagtga ttatattgtc agctttgaaa tcattgaatt tgtagcggat aaagaagaat
     8521 aaaaactgga ggaataaatt ttacagataa aggcttagaa ggagtcacga tgattaataa
     8581 aaaggtagta ttaccttagg cattgagtaa gga
//
LOCUS       DAFEIE010000089         8246 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFEIE010000089
VERSION     DAFEIE010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.092"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(365..1156)
                     /gene="msrA"
                     /locus_tag="LP345_002523"
     CDS             complement(365..1156)
                     /gene="msrA"
                     /locus_tag="LP345_002523"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL1761273.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1347..1982)
                     /locus_tag="LP345_002524"
     CDS             complement(1347..1982)
                     /locus_tag="LP345_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBL1761274.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYRLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(2248..3300)
                     /locus_tag="LP345_002525"
     CDS             complement(2248..3300)
                     /locus_tag="LP345_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1761275.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(3313..4251)
                     /locus_tag="LP345_002526"
     CDS             complement(3313..4251)
                     /locus_tag="LP345_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL1761276.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(4702..5352)
                     /locus_tag="LP345_002527"
     CDS             complement(4702..5352)
                     /locus_tag="LP345_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761277.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(5452..5961)
                     /locus_tag="LP345_002528"
     CDS             complement(5452..5961)
                     /locus_tag="LP345_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBL1761278.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(6046..6525)
                     /gene="rlmH"
                     /locus_tag="LP345_002529"
     CDS             complement(6046..6525)
                     /gene="rlmH"
                     /locus_tag="LP345_002529"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBL1761279.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            6953..8242
                     /locus_tag="LP345_002530"
     CDS             6953..8242
                     /locus_tag="LP345_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBL1761280.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENIKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
BASE COUNT         2616 a         1674 c         1318 g         2638 t
ORIGIN      
        1 tagttattgt ttgcgctttt atacggaatt tagttcatca ttaatgtgga attcgattag
       61 gtgtctatta attatcaaga tgattctcta caaaattcca tagaaaaatc aagattctac
      121 aattcgaatt ctctttcaca tggaaataaa ggctagtaaa aaaacaggag ttgtgacaaa
      181 agacttgtca tacctcctgt ttccttgcga cttgaagctg aatgctttgc gccacaacct
      241 tttcctcggt gttctcaaag caactcctcg aaataattca taactgtcca aaaatatgaa
      301 aagctatttt tgtcagttgc tcattatttt gtcggagctg aacgctttgc gccacaacct
      361 tcctctatct atgtcgctga aaaaataaat gaagctgatg cgaatgcttg atctttttat
      421 atcttttagg ttgcttctga taaaattgtt gatgatgatt ttcagctggc caaaaagtct
      481 ttgcttggcg aatctctgta acgataggac ggctaaatcg gttagattga atcagttgtt
      541 ctcttgattt ttcagccaat tgcctttgct tttcattaac aacaaataga attgaacgat
      601 attgtttccc ccgatcttga aattgaccaa aggcatctgt agggtctgaa atttgccaat
      661 aaatctccaa cagctcttca taggttattt gacgtgtatc aaatatgatc tcaacagctt
      721 caacatgccc agtatatcca ccactgactt gatcgtaatt tggttttttg gtctctccac
      781 ctgtataacc agataacact gagattacac ctggttttgt ttcaaaaggc tcaaccatac
      841 accagaaaca gccaccggca aaaatcgccc gttcttggta taagggtgaa gttatcttat
      901 gtttggcata atcataagcc tttgcactcg ctgactcccc tgtgattctt aaataaaaat
      961 ccatcgcatc tggtgtcaaa ttatctcgta gtgctagcgg acgcaagttg acctctagtt
     1021 tttctatcac ctgctttatc gacatttttg ctaggtcttc ttttgcctct tcaaattgtg
     1081 ttctttccca ttctcttgta tttcgattta aaataatatt ataaaggtct atttccatct
     1141 gctccacatc taacatgaag tcaccctctt tcaagttttc ttcttattca ttcaaaaaat
     1201 gactacctga aatttagcac aacgcataac aagttaagac taacttgctt ttcgctctcc
     1261 tcatctctat tcttagtcga acacatccac acgaatggtt acccatagag aaattctttt
     1321 acttaatcag cttcacactg ctttttctac tttcgtagtt gaaaaaaact taaacaaatc
     1381 atcggcaaat agttaaagaa aaaacttaag cgttgaaaga agcccaattg cttaaagaag
     1441 gcaaactgac taatcgacgg aatccgtgct aatctgtaaa gacctgcaat tagtaaacta
     1501 ataactgtta aaacaagata aaaatggcta agcgtacctt gaccactttg acgataaagc
     1561 agaacaagta acaatgggaa aagtagaaag cctgcatagc ctagcccaga acctatatta
     1621 tggatccaag tcgatagatt ccaagagctt tcattcgtat tgatactgaa taacccagta
     1681 aaaatacaat cacctatccc atataaacca actgttgcaa cagcaagtat tgcaagtgtt
     1741 tttgatgttc caataaatag gtgatacaac gcaggcaacg aaagaacaaa aaaaagtcca
     1801 gatacaactg accagaccaa gaaagcacgt ctgactggac tatctacgtc accaaacaca
     1861 ctaattacgg tagtcatttg attcagtttg ggataaaaaa ggccaaggat atacggtgtc
     1921 gataaatcac taatcacacc taataataaa aaataaaaac catatttttg caaaaaaatc
     1981 attttcttct cctacttttt agtgattatt cgatacatcc aacaatcaaa ttttttctca
     2041 ttttaacaca tatttttatt ctagttgcct tttgaacaat caataacata aaggtgagtt
     2101 tcttctacat tttaaaaaat cgaatggcac tgaagagttc agttgtcagc atcaatctcc
     2161 tactcaaaaa ggcaaaaaaa cgtaagtcag atgttgttga catctcactt acgcatccat
     2221 tgattgaaaa tttcttagta aaatctacta gcctaaaaat ttgaagactt cttctcgatc
     2281 atacagttta aatactttct cgcataaaaa ttgagtaatt agtgccgcaa aaacagggat
     2341 gactaaccaa caaagaacaa caagaaagcc atttagccct gcatctaaag aagccaacgg
     2401 accaacaagt ccgaccacgc cgaaaccagc agaagcaggc gtacctgaaa tagaaaatag
     2461 agcgacagga atagctgtaa tcactgcact aactaaacaa ggaataagaa tcacaggttt
     2521 tctaaataga ttaggcatca tcatcttcat agcgcctaaa gcaatcgcaa ttgtcacacc
     2581 tgacttatta accttccaag agttcactac taaaacaaaa gtggttgcag ctacgcccat
     2641 cgcagccgca ccagcagaaa caccatctag ttggattgcc attccgattg ctactgttga
     2701 aataggagag ataatcaaaa aggcaaagga acaaccaatc aagatagaca ttaacagcgg
     2761 ttgtaaggta gtgaagttat taatcaatga tccaattgca gaagtaattg ctgttacaaa
     2821 agggaataaa taaaaaccaa gtaaacctgc acctacacct acaacaatcg gtgttaacac
     2881 aatcgacact gacccaaaac tatttccaat cagtaaaatc agcccgacag caatcgatgc
     2941 tgtcagcatc gtattaataa tatcgcctgt accagcacca acgtaaacac ccgtttcacc
     3001 caaatcaggt gtgaatttga ctacaccaga accaacaaaa gaagctccgg ctacaaccat
     3061 cattctcatc ggatcaaatc caaattgtaa ggcaatcaaa ccaccaatga tcaaaggtgt
     3121 tgctagttga aaaataactg ctaactgtgc gatcgttacc gcaaagggat acgcactaaa
     3181 atattttaaa atggcaccta atactgcatt aggaatcaat ccaataatga ttcctgttgc
     3241 tgtaccagcg aggactttat tcagaaaaat tttcggtgat attttttgtg aagtttccat
     3301 tcaatctctc ctttatttta cgttcaaact atcttctttt gcatggacaa gctcagtcaa
     3361 gaaatcacaa taaggcgtcg caacaccata tttcttccct tttctagaaa ttgcgccatt
     3421 gatataatcg atttctgtta atcgatggtt cttaatcaag tcttgataca ttgaaggata
     3481 atgtaaccca attgtttccg ggtcaaaaca agattcacaa tgtgcaatga cttctgggac
     3541 atctagttca atcttctcta ctgctgctac tttggcaaac tcattgacaa tcgtcgccac
     3601 cattttatga gcagtcgatg tttttcctag ctcagccata ttaacgtcta agattgtgca
     3661 tagtccgttc attgttccgt tcacacatgc tttgcgataa atagaatagt gaatattgtc
     3721 agaaaaatga gcatttaatc ctgattcaga caatttgtct gctaattttt ttgcagctgc
     3781 ttcttttcca tcacctaaat tttgtaattc tactgaacca cttccaaata atttgacctg
     3841 accaggacct tcaagacctg ccgtccacat ggtatttcca atatagatat tttccattgg
     3901 tacaaatttc tcaataatat cttcatgccc gataccattt aatagacata agacctctgt
     3961 atcttttttg attaatgatt ggatatcctg cagcattttt tccagctgca tcgctttggt
     4021 aaatagaata atcagatcaa cttgatcttc tttttctact tcggattgaa gaacgattgg
     4081 tagttttgct tctacctctt taccattaaa atttgcttgt aatccatgct ctttgatttg
     4141 ttggacatgt tctgcccagc catctattaa taatacttcg ttcccacttt ggtgaagcat
     4201 taacccaaag cgacttccca ttgcgccagc gcctgcaatt gctattttca ttgattcttc
     4261 ctcctttttc tttctattat attcatttga gaatcatttc acaaccttgt tttgttattc
     4321 ttctcttatt tatcatgttt atatccacca ttcaagttat tttatcagca aatcaataaa
     4381 aactggaata gaatcccaat ttcatcgtaa gagaaactag actagcaata agaaaataga
     4441 aacattcata gaaaaaacct cactcctctg attataaaag agggggcatt aacctcgtgt
     4501 atactaaaac cttccattca ttcgatggat gattttcttt ttgtgaaaaa atattcattg
     4561 tagtacgatg ttgcgcaaca cagacggatg gtattgctta ttatttatta aaatcgaaca
     4621 atacacttat ttaaaaactt ctttcccaga ttttcttcca tttttacagt tataactagt
     4681 attatcatga aaaatagcct tttattgtct atgggaataa taatttaaaa ttggtacttt
     4741 tttattaatt agttcatcgc ccaataatct ctccagtttc ttagcatctc ctgactcaac
     4801 cggaattatc caagcccagt ccaaataatt ttttaaaatc tcatcatatt ttgcaaatat
     4861 ttcattgcca tattccgtcc ttaaaattat attttcagtg ccagacaagt gatttgtatt
     4921 gagttgataa aaaagatctc catctaaaaa aatatcatta gaagaagatt tccccacagt
     4981 aatgaccatt ccatcagctc tatgtgttac atacaaataa ttgtatgacc tcatttcacc
     5041 taatgaatca attatttctt gccctttagc tctaatatat tgatctctat tacctatctc
     5101 actcttattt aacaaaagtt ttttcatgtc aaatttaatc ggctgtttta tttttgtaaa
     5161 ttcgcttcta ctactaatcc aatccgagat taatttttca acatgtccca gagtaaactc
     5221 tgatttattc gctaaatact ttttttgttg tattaaagac atctttcccc gaagctcaaa
     5281 attgagccta catcgattct ctatctcttc aaaaagcatc ttatcttcat cattcttata
     5341 ttcatcattc ataaaaccaa tccagctcct cgattaagat aatattttaa tctcatacaa
     5401 aaactagctc tcatcaaaac aaccattgtt ttgatttctc atgaaatttc tttatacttt
     5461 tctccgatta taaattccta accccttgag aaaattacgc atatatttat ctccgcaagg
     5521 cttaaaattt cgttggcctt cttttctcaa aaatgccccg atttcgcctt ttgatggata
     5581 gatttctgcc tcagcaaaaa cgtctaaaat atcatcagtg gtcatagaca aggcgatttt
     5641 taattttttt agcaacacat tgttgatata tttgatttcc ttgctttttt gcggcgtgtc
     5701 tactatcggc ttatcttttt gcggaccacg cgccaagaga atcaggccat ttaggaatgc
     5761 gtcaaaaact tggttgttga tggttttttc atacacatta ttttctgcat tatctttgtt
     5821 cttatcctgt actttggtca gtaccgcctg agcttcttct ttagtcagtg gtacaccgcc
     5881 tagctcaaaa gctttaatca aatccgtatc tttcaaatca atcgcataac gcaatcgcaa
     5941 taacctatca ttgttattca tttgttcctc cgaagtattt agtctttact ttcttacgta
     6001 ctttttgtct tgctaagatt tttaggatca atgataaaaa ccgcatcact tatgataagg
     6061 cgcccccgca ttgatccgga aggcacggta gatttgctcg acaaggatca gacgcatcaa
     6121 ttgatgtgga tacgtcattt ttccaaaaga gatctgagca ttgcttcttt tcatgacggc
     6181 ttcgctgagt cctaaagagc cgccgataac aaaaacaagg tggctttttc cttggatacc
     6241 taattggtcg atttgtttag caaaagattc acttgtagga tttttccctt caattgctaa
     6301 ggcatagacg tattcttgtt ctttgatttt cgctaagatc cgttcccctt ctttttcttt
     6361 tacttgtctc atttgcgctt cgcttaaatt ctccggggct ttttcgtcag gaacttcgat
     6421 caattcgatt tttgcatagg cattcagccg tttgacatac tcattgatac cttggatcag
     6481 gtatttttct tttaattttc ctactgagat aattttgata ttcatgtttt ctctcctttg
     6541 gtcttcatgc tcactttgtt tattataatc aattttttcg tctatatgtt tattttggct
     6601 atttttgtta aaaagatttc cccaacagtt atgcacaaca tccacaggtt tatccacaga
     6661 aaacagtgtt attttacctt atttcatcac attcattagg caaacatacg ttttataaga
     6721 atttatccac tttatacaca ggctgtggat atgttttatc ccttattttt ccaatcctat
     6781 ccgcgtagtt ttacacagta tctgtggaaa aagaaaatca aatattttca tctgaaaaca
     6841 atgatttttc ctaaagtttt tcataaaaag ttcacagtct caaagtagac taaagtcaac
     6901 aaataagact atactaacag tagataaatg aatgtaattg gaggaggaac acatggatag
     6961 aaaaaatgtg acaccaaaga tgaaaaaaag taaaaataat agcctctggc gtaagttagg
     7021 tctggggctt gttggaggga tcgttggagg actactgaca gctggcattt tttatgcagc
     7081 gatgggcact ggcaacaata gttctactgc tacaagcggc aatcagaatt ctgccggtga
     7141 aacagttgtg gaaaatatca aagtcaatgt agattctgat atcaccaaag cggtagataa
     7201 agttcaagac gctgtcgttt ctgttatcaa cttacaaagt caaaaccaat caagcggttt
     7261 tggcggacta ttcgggcagc aagaagaaag tagcagctca gatgatagta atttggaagc
     7321 ttatagtgaa ggaagcggcg tgatctacaa aaaagacggg aatactgctt atgtagtcac
     7381 gaataatcac gtagtagatg gccagcaagg tcttgaagtc ttgatgaaag acggtacgaa
     7441 ggtaaaagct gaattagttg gaacagatgc ttattcagat ttagcggtgt tgaagatcaa
     7501 ttcagacaaa gtcgaaacag ttgcctcttt tggtgactca agtgctctga aggttggtga
     7561 gcctgcgatt gcgattggtt ccccactagg atctgaatat gcaaattctg tcacttcagg
     7621 aatcatttct tccttgaacc gacaagtgac aagtacgaat gaatcgaacg aaacagtcaa
     7681 tatcaatgcg atccaaacag atgcagcaat caaccctgga aattctggtg gtcctttagt
     7741 taatatcgaa ggacaagtta tcggtatcaa ctcaagtaag atcgcaagta cttctgaatc
     7801 tacttctaat gtaagcgtag aaggaatggg atttgctatt ccaagtaacg atgtagtgaa
     7861 tatcatcaat caactggaaa aagacggaaa agtgacacgt ccagctctag gtatcacaat
     7921 ggtcgactta tctgccgttt ctactcagca acaagaacaa atcttgaaga ttccttcatc
     7981 tgtaactaac ggtgtcatcg tgacaaatgt ccaaacagct acaccggctg aaaaagctgg
     8041 attgaaacaa tacgacgtca ttactaagat cgatgacaaa gaagtttctt ctggtgtaga
     8101 acttcaatct gctttgtata agaaaaaagt gggagattct gtcaaaatca cttactatga
     8161 aggctcgaaa gaaaaaacaa ctactgttga attgacgatc gatcaatcgg cattaaaaca
     8221 aaatcaaaat agtgaaaatt aataaa
//
LOCUS       DAFEIE010000090         7689 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFEIE010000090
VERSION     DAFEIE010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.095"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            193..1161
                     /locus_tag="LP345_002531"
     CDS             193..1161
                     /locus_tag="LP345_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL1761281.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1154..2185
                     /gene="vanA"
                     /locus_tag="LP345_002532"
     CDS             1154..2185
                     /gene="vanA"
                     /locus_tag="LP345_002532"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL1761282.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2191..2799
                     /locus_tag="LP345_002533"
     CDS             2191..2799
                     /locus_tag="LP345_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL1761283.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3205..4137
                     /gene="vanY"
                     /locus_tag="LP345_002534"
     CDS             3205..4137
                     /gene="vanY"
                     /locus_tag="LP345_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBL1761284.1"
                     /translation="MVKEETENEEVVFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYD
                     QNPKEHLENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDEL
                     INGYGLLDSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAE
                     YALPAGYSEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQ
                     YEPWHIRYVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTT
                     IHVPTNLRYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4290..4775
                     /gene="vanZ"
                     /locus_tag="LP345_002535"
     CDS             4290..4775
                     /gene="vanZ"
                     /locus_tag="LP345_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL1761285.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5062..5391)
                     /locus_tag="LP345_002536"
     CDS             complement(5062..5391)
                     /locus_tag="LP345_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1761286.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5696..6025
                     /locus_tag="LP345_002537"
     CDS             5696..6025
                     /locus_tag="LP345_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1761287.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6015..6302
                     /locus_tag="LP345_002538"
     CDS             6015..6302
                     /locus_tag="LP345_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1761288.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6581..7144)
                     /locus_tag="LP345_002539"
     CDS             complement(6581..7144)
                     /locus_tag="LP345_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1761289.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         2533 a         1278 c         1531 g         2347 t
ORIGIN      
        1 aattttttag gaaaatctca aggttatctt tactttttct taggaaatta acaatttaat
       61 attaagaaac ggctggtaga cttaataccg taagaacgag ccgttttcgt tcttcagaga
      121 aagatttgac aagattacca ttggcatccc cgttttattt ggtgcctttc acagaaaggg
      181 ttggtcttaa ttatgaataa catcggcatt actgtttatg gatgtgagca ggatgaggca
      241 gatgcattcc atgctctttc gcctcgcttt ggcgttatgg caacgataat taacgccaac
      301 gtgtcggaat ccaacgccaa atccgcgcct ttcaatcaat gtatcagtgt gggacataaa
      361 tcagagattt ccgcctctat tcttcttgcg ctgaagagag ccggtgtgaa atatatttct
      421 acccgaagca tcggctgcaa tcatatagat acaactgctg ctaagagaat gggcatcact
      481 gtcgacaatg tggcgtactc gccggatagc gttgccgatt atactatgat gctaattctt
      541 atggcagtac gcaacgtaaa atcgattgtg cgctctgtgg aaaaacatga tttcaggttg
      601 gacagcgacc gtggcaaggt actcagcgac atgacagttg gtgtggtggg aacgggccag
      661 ataggcaaag cggttattga gcggctgcga ggatttggat gtaaagtgtt ggcttatagt
      721 cgcagccgaa gtatagaggt aaactatgta ccgtttgatg agttgctgca aaatagcgat
      781 atcgttacgc ttcatgtgcc gctcaatacg gatacgcact atattatcag ccacgaacaa
      841 atacagagaa tgaagcaagg agcatttctt atcaatactg ggcgcggtcc acttgtagat
      901 acctatgagt tggttaaagc attagaaaac gggaaactgg gcggtgccgc attggatgta
      961 ttggaaggag aggaagagtt tttctactct gattgcaccc aaaaaccaat tgataatcaa
     1021 tttttactta aacttcaaag aatgcctaac gtgataatca caccgcatac ggcctattat
     1081 accgagcaag cgttgcgtga taccgttgaa aaaaccatta aaaactgttt ggattttgaa
     1141 aggagacagg agcatgaata gaataaaagt tgcaatactg tttgggggtt gctcagagga
     1201 gcatgacgta tcggtaaaat ctgcaataga gatagccgct aacattaata aagaaaaata
     1261 cgagccgtta tacattggaa ttacgaaatc tggtgtatgg aaaatgtgcg aaaaaccttg
     1321 cgcggaatgg gaaaacgaca attgctattc agctgtactc tcgccggata aaaaaatgca
     1381 cggattactt gttaaaaaga accatgaata tgaaatcaac catgttgatg tagcattttc
     1441 agctttgcat ggcaagtcag gtgaagatgg atccatacaa ggtctgtttg aattgtccgg
     1501 tatccctttt gtaggctgcg atattcaaag ctcagcaatt tgtatggaca aatcgttgac
     1561 atacatcgtt gcgaaaaatg ctgggatagc tactcccgcc ttttgggtta ttaataaaga
     1621 tgataggccg gtggcagcta cgtttaccta tcctgttttt gttaagccgg cgcgttcagg
     1681 ctcatccttc ggtgtgaaaa aagtcaatag cgcggacgaa ttggactacg caattgaatc
     1741 ggcaagacaa tatgacagca aaatcttaat tgagcaggct gtttcgggct gtgaggtcgg
     1801 ttgtgcggta ttgggaaaca gtgccgcgtt agctgttggc gaggtggacc aaatcaggct
     1861 gcagtacgga atctttcgta ttcatcagga agtcgagccg gaaaaaggct ctgaaaacgc
     1921 agttataacc gttcccgcag acctttcagc agaggagcga ggacggatac aggaaacggc
     1981 aaaaaaaata tataaagcgc tcggctgtag aggtctagcc cgtgtggata tgtttttaca
     2041 agataacggc cgcattgtac tgaacgaagt caatactctg cccggtttca cgtcatacag
     2101 tcgttatccc cgtatgatgg ccgctgcagg tattgcactt cccgaactga ttgaccgctt
     2161 gatcgtatta gcgttaaagg ggtgataagc atggaaatag gatttacttt tttagatgaa
     2221 atagtacacg gtgttcgttg ggacgctaaa tatgccactt gggataattt caccggaaaa
     2281 ccggttgacg gttatgaagt aaatcgcatt gtagggacat acgagttggc tgaatcgctt
     2341 ttgaaggcaa aagaactggc tgctacccaa gggtacggat tgcttctatg ggacggttac
     2401 cgtcctaatc gtgctgtaaa ctgttttatg caatgggctg cacagccgga aaataacctg
     2461 acaaaggaaa gttattatcc caatattgac cgaactgaga tgatttcaaa aggatacgtg
     2521 gcttcaaaat caagccatag ccgcggcagt gccattgatc ttacgcttta tcgattagac
     2581 acgggtgagc ttgtaccaat ggggagccga tttgatttta tggatgaacg ctctcatcat
     2641 gcggcaaatg gaatatcatg caatgaagcg caaaatcgca gacgtttgcg ctccatcatg
     2701 gaaaacagtg ggtttgaagc atatagcctc gaatggtggc actatgtatt aagagacgaa
     2761 ccatacccca atagctattt tgatttcccc gttaaataaa cttttaaccg ttgcacggac
     2821 aaactatata agctaactct ttcggcagga aacccgacgt atgtaactgg ttcttaggga
     2881 atttatatat agtagatagt attgaagatg taaggcagag cgatattgcg gtcattatct
     2941 gcgtgcgctg cggcaagata gcctgataat aagactgatc gcatagaggg gtggtatttc
     3001 acaccgccca ttgtcaacag gcagttcagc ctcgttaaat tcagcatggg tatcacttat
     3061 gaaaattcat ctacattggt gataatagta aatccagtag ggcgaaataa ttgactgtaa
     3121 tttacggggc aaaacggcac aatctcaaac gagattgtgc cgtttaaggg gaagattcta
     3181 gaaatatttc atacttccaa ctatatagtt aaggaggaga ctgaaaatga agaagttgtt
     3241 tttttattgt tattgttatt cttaatatac ttaggttatg actacgttaa tgaagcactg
     3301 ttttctcagg aaaaagtcga atttcaaaat tatgatcaaa atcccaaaga acatttagaa
     3361 aatagtggga cttctgaaaa tacccaagag aaaacaatta cagaagaaca ggtttatcaa
     3421 ggaaatctgc tattaatcaa tagtaaatat cctgttcgcc aagaaagtgt gaagtcagat
     3481 atcgtgaatt tatctaaaca tgacgaatta ataaatggat acgggttgct tgatagtaat
     3541 atttatatgt caaaagaaat agcacaaaaa ttttcagaga tggtcaatga tgctgtaaag
     3601 ggtggcgtta gtcattttat tattaatagt ggctatcgag actttgatga gcaaagtgtg
     3661 ctttaccaag aaatgggggc tgagtatgcc ttaccagcag gttatagtga gcataattca
     3721 ggtttatcac tagatgtagg atcaagcttg acgaaaatgg aacgagcccc tgaaggaaag
     3781 tggatagaag aaaatgcttg gaaatacggg ttcattttac gttatccaga ggacaaaaca
     3841 gagttaacag gaattcaata tgaaccatgg catattcgct atgttggttt accacatagt
     3901 gcgattatga aagaaaagaa tttcgttctc gaggaatata tggattacct aaaagaagaa
     3961 aaaaccattt ctgttagtgt aaatggggaa aaatatgaga tcttttatta tcctgttact
     4021 aaaaatacca ccattcatgt gccgactaat cttcgttatg agatatcagg aaacaatata
     4081 gacggtgtaa ttgtgacagt gtttcccgga tcaacacata ctaattcaag gaggtaagga
     4141 tggcggaatg aaaccaacga aattaatgaa cagcattatt gtactagcac ttttggggta
     4201 acgttagctt tttaatttaa aacccacgtt aactaggaca ttgctatact aatgatacaa
     4261 cttaaacaaa agaattagag gaaattatat tgggaaaaat attatctaga ggattgctag
     4321 ctttatattt agtgacacta atctggttag tgttattcaa attacaatac aatattttat
     4381 cagtatttaa ttatcatcaa agaagtctta acttgactcc atttactgct actgggaatt
     4441 tcagagagat gatagataat gttataatct ttattccatt tggcttgctt ttgaatgtca
     4501 attttaaaga aatcggattt ttacctaagt ttgcttttgt actggtttta agtcttactt
     4561 ttgaaataat tcaatttatc ttcgctattg gagcgacaga cataacagat gtaattacaa
     4621 atactgttgg aggctttctt ggactgaaat tatatggttt aagcaataag catatgaatc
     4681 aaaaaaaatt agacagagtt attatttttg taggtatact tttgctcgta ttattgctcg
     4741 tttaccgtac ccatttaaga ataaattacg tgtaagatgt ctaaatcaag caatctgatc
     4801 tttcatacac ataaagatat tgaatgaatt ggattagatg gaaaacggga tgtggggaaa
     4861 ctcgcccgta ggtgtgaagt gaggggaaaa ccggtgataa agtaaaaagc ttacctaaca
     4921 ctatagtaac aaagaaagcc caattatcaa ttttagtgct gaggaattgg tctctttaat
     4981 aaatttcctt aacgttgtaa atccgcattt tcctgacggt acccccaaac taagatttca
     5041 tagatagatt ttctgataac tttaaaaaac acgaatagcg gaaaggatgt cttcattcgc
     5101 taaagagtaa taaactactt ttccatcttg acgtgatttt gccattccat gtttttttaa
     5161 aaaacgtaaa tggtgtgacg ttgtagcgac actagcagta agtatttctg ctaaatcaca
     5221 gacgcacatt tccttatagg tttctaaagc atagaaaatt ttaattctag aaaaatcgct
     5281 gaaacatttc cctaacacaa gtaagtttga aaaatctttt tgatccaatt tattttttat
     5341 tccatttact ttttctttat gtacgacagt cacttggcaa acttttttca ttcatctcac
     5401 ctcacattca aacgattatt tgaatgaagt atacctattt gatcactctt ttgtcaatct
     5461 accttaattc caatacacta ttataagcaa tttcatgtat tgaagtaaac ttacttgcaa
     5521 gtgcgttttt gattccaagt taaaaacata ttattattct acataatttc ctaatcaaat
     5581 aaaactcctt tgaaaattgt tctaaaggag ttttattatt ttgtatttct actaaaaata
     5641 gcgtacaatg taattactaa gtaattacga aatgtaaaat aatggaggaa ataatatgat
     5701 tacaaaaaca agaaaacaag gaaattctat tatgttaacg gtccctaaag aattcgatgt
     5761 gcccaatggt gttgaagtag aagctaagct tgtagagaat ggtatccttt atgagtttgt
     5821 agagcctaaa aaagaatttt ttgattttag tgaagatatt ttggctgata ttctttcaga
     5881 aggttatagc aaacaagaga tcttaaaaga atttagaaat agaaaaaatg cgttaacttc
     5941 tgcatttaaa tctattgctg aagatactgt tgcaaattct aaaccgatga caaaagagga
     6001 gttggcagca gaaattggct tatgagattc taccttctaa acacgtaata aagtatctaa
     6061 aaaaattaaa agagaaaaca ttaaaagaac aatttttaac gataatttat gatgagatag
     6121 cagttcgtcc tcattcggga gaacaaaaaa cgggtgattt atcaggaatt tgggctattg
     6181 gattcaagta tgcaggtacg acatatcgcg ttgcatatga aattaaagat aatgcagtga
     6241 tacctatctt actatgtgga acgcatgaaa atttttatga acaattaaaa aagattaggt
     6301 aagaacccaa tgtttcaact tgagaggata gacgacactt taaaagataa tttttaacag
     6361 ctgagagttg taatacccta taattttaaa ccactaacct atatatttat gaaaaataga
     6421 aaaaattaaa acgcatttta agcctctttc aaattaaaag cttcatcctt atgcacaaag
     6481 agggcttaaa atgcgttatt ttatattgtt ttttagtaat aataaaaaaa tcactctaat
     6541 tctcccataa atattataga ttcctaaaga ttaaaataga ttattcccta ttgtctttta
     6601 agtagcggta gagtgttgcc ttgctaatac cagtcatttc cgtaatttct tttacgctat
     6661 aaacctgact tttatacaat tttactgctc gatcaacatc tttctggttc actcgtggac
     6721 ggccaccttt acgacctctc gcacgtgcac ttttcaaacc ttctttggta cgttcaacaa
     6781 ttaaatcacg ttcgaactga ctaaatgctt ggaagacagt catcattaag cgtccgtgag
     6841 gcgtgctggt atcgaagttt tctttcaagc tcaccagctt aacatggtgt tcttcaaaat
     6901 aggtaacaag gtcaatcaaa tcctttgtac tacgacccaa tcgagaaaaa ctttctacaa
     6961 ttaccgtatc tcccggacga attttatctt ttaaacgatt tagttgggga cgaaccgctt
     7021 tggttcccgt cattttctca gttaggattt cattacaatt ttgttcattg agtaagtcta
     7081 attgacgatt tagttcttgt gaacgtgtac tcactcgggc ataaccataa atgtatccac
     7141 tcatgctttt cttcctttcg tactttaatt ctggcttgat tgtatcataa aagggagtta
     7201 tagatacata gttaatgcaa caagttatga tacaaaatat gacctctttt atttaataaa
     7261 agaggtcatt tcattttgtc tcataatcga ttgtttttga tacgagtgtg tatacgaaat
     7321 aaacaaaaaa atcttaagta aatttctaga tacctaattt aatcctaact agtgtatcct
     7381 aaagttaata acgagtttat cacaatgaaa attataaaat gctcccatat tagatataac
     7441 atgcaatatt tgaattagaa ctacaaaatt tattcgtttt ataaagtaaa taatgttgag
     7501 atactaagga atagaatatt ataaggaatt gagctgaatg tattggataa aaaaagaata
     7561 actttattag agatggacta taaaaatgct cgtaattttc ttctgaagtc tgaaagctat
     7621 ttgaatgctc agctaccaga atatattagt tttgacgaaa ctttaaaatc tgctaaaaaa
     7681 gttttaact
//
LOCUS       DAFEIE010000091         7624 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFEIE010000091
VERSION     DAFEIE010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.096"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(14..706)
                     /locus_tag="LP345_002540"
     CDS             complement(14..706)
                     /locus_tag="LP345_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL1761290.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="LP345_002541"
     CDS             complement(1143..1712)
                     /locus_tag="LP345_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1761291.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="LP345_002542"
     CDS             complement(1786..2109)
                     /locus_tag="LP345_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761292.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="LP345_002543"
     CDS             complement(2263..3075)
                     /locus_tag="LP345_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761293.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="LP345_002544"
     CDS             3429..4277
                     /locus_tag="LP345_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBL1761294.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="LP345_002545"
     CDS             4422..5363
                     /locus_tag="LP345_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBL1761295.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="LP345_002546"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="LP345_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1512 c         1371 g         2469 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaaa
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag ttacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgagaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgaa tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagctttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaacgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tcgaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacc
//
LOCUS       DAFEIE010000092         7595 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFEIE010000092
VERSION     DAFEIE010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.097"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(939..1352)
                     /locus_tag="LP345_002547"
     CDS             complement(939..1352)
                     /locus_tag="LP345_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBL1761296.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1808..2293)
                     /locus_tag="LP345_002548"
     CDS             complement(1808..2293)
                     /locus_tag="LP345_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761297.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2432..2677)
                     /locus_tag="LP345_002549"
     CDS             complement(2432..2677)
                     /locus_tag="LP345_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBL1761298.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2870..3670
                     /locus_tag="LP345_002550"
     CDS             2870..3670
                     /locus_tag="LP345_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1761299.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3689..5557
                     /locus_tag="LP345_002551"
     CDS             3689..5557
                     /locus_tag="LP345_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL1761300.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNAVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5550..6041
                     /locus_tag="LP345_002552"
     CDS             5550..6041
                     /locus_tag="LP345_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBL1761301.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6029..6583
                     /gene="srlA"
                     /locus_tag="LP345_002553"
     CDS             6029..6583
                     /gene="srlA"
                     /locus_tag="LP345_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBL1761302.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6601..>7595
                     /locus_tag="LP345_002554"
     CDS             6601..>7595
                     /locus_tag="LP345_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBL1761303.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1214 c         1441 g         2233 t
ORIGIN      
        1 ttactatgaa taacataata agaaagtaaa gtggattgat ttgagatctt tttatacttc
       61 aaaaaagata acacccaact ttcaaaaata tgttttggaa gttgggacaa acgagttaat
      121 acattttaat acattatttt ttattcaaaa aaaatagcac aatggcaaag atcgtaagag
      181 agatcataag ccccaatgaa tgactaaaaa gaaaagcaga atcacatgcc atatcatccc
      241 atatttcttc aagaaaataa ataagcggga aaaagggaag gaatagtaga acatcgatcc
      301 agcaccattt ttttcttctt ttgaaataac ataaaacaat aaacatgaac gtgcagggaa
      361 gtaaaaacaa agctttactc ataactaaca aaataccagc tccttttatt tttttctccc
      421 ccacattcaa agagtaacaa tggtatgtac ttaataatag aaaaatggat caacttgtat
      481 gaataacagc tgaaaagatc tgcaccaaat aaaaaacttc cagccaaaac tgactggaag
      541 tttatttttt tctgaaatat tctaacacaa atatgaaaaa gatggccgaa gctaataagc
      601 cgatttcgta gcaaaacaat gagataccag agtcgtaata ataaaatcct ctaatcttat
      661 ggataaaata gatcatcgga caagcagata agagtaagta tttgttaggc cttttgaata
      721 agtaaaagaa agcactggtc attatgataa atggtatcca aaacaaaagt ttacttaaga
      781 caatcaaatg atcaactccc atatttttta ccaagagaga tcataacatc tttatcgtaa
      841 aaacaaaata tttttttgct cattttgaaa atttaaacat actcgttctt atccaaatat
      901 ataaaaatcg cccctcattc atcgagaggc gataagttct aatttaactc aatttttttt
      961 gtttcttttg gctgataagc tgttttaggt aataccaatt tcagcacacc gtttttaaag
     1021 gttccagtga ttttttcttc atcaacatta ggaagataga atgaacgttt gtaagagacc
     1081 gaatgtcttt ctttccgtac atagttgcca tcttctttat cttctgtatg ggactcatga
     1141 ttggcggaga tcgtcaaagt attatctgaa tattcaactg tcgtgtcttc tttgtcacag
     1201 ccaggcatat cagcagttag tttgtattct ttttcatttt cgactaaatc tacttttgga
     1261 taacttgaaa cacctaaaaa atcattgaat gctggactaa acacgtcatt gaaatcaggg
     1321 aacatgtcgc gaatgctagg tacatttgcc atttttgatc atcctttcaa taagtatttt
     1381 ttatttatcc ctatttacgt aataactcta ttttgaaaaa aatgcaagta taatggttag
     1441 ctttgtgaat atttcatcta atacgataca aaggctatct ttctaatttg aaaaagggat
     1501 cattaaaata ataagaagaa aatatgtcaa aaggtaaaaa agtaaattct tctatccaaa
     1561 tatagaaaaa ttgaatatag aaaaccgccc gacaataaat ttcattaact cagttgaccg
     1621 aaaatgaagt agataccaaa aatttatcaa gagagcaagt agagaagtga gtatattcat
     1681 aagagaaata gctgtaacga attattaggt taatgcaaat gcttatttat actccgtata
     1741 actttctcag aaaaaatgat accaataatg acttgctagt actgtaaatc cgtataatat
     1801 catctaatca aaatggtgtt ccatttgcat ctgtcatcgt aatcgatcct tcgggtgaca
     1861 ctcgataaaa accaacgctt ccagatcctc cttgggaacg gatttgtttg ctggaagctg
     1921 tgaacaaata atctcgatca attttttgat aaaagctaat aacaatatcg tcactttgta
     1981 attcggaacg gtgggcaata agaaatagaa gtgctttgtc agagttttct aatggaagag
     2041 aaggtacagt gctttcttgc atttcagatg ttgaagaaat gctaaacgac tgaatacttg
     2101 attggctatg ttgcgaatct acattaccag tagaagtatt agtaatggaa gtagtagaag
     2161 tacttttagt tgaaccaacc tcagttgttg aaatggctgc tgaagattct ttaacagaat
     2221 tctttgtttt atatccacag gcagaaaaaa gtattacagt tcccaacaag cctgcgtaaa
     2281 tccctttatg catgatagct cctcctaaaa tagattatct ttattcagta tatcacttaa
     2341 acaaagaaaa gcagatggtt taaaatgaaa aaaccttccc aataaaggga aggttcatga
     2401 agataataac ttttttaata attatagctt tctaatatct ttcatcaact tttctagtaa
     2461 tcattgggaa aaatttcaag cagtagatcg cacaaatacc tacgacgata taaatgatct
     2521 tcgcaaaaat agttgttgaa ccaccagcaa tcatagctac taaatcaagt tcgaacaagc
     2581 ctaccaacag ccagttcaac cctcccacaa tcaataaagt taatgcaata gcatctaagt
     2641 tttcattaga attctccttt cttaaatgat aaaacaatta tatatcaaaa agagaaacat
     2701 tgcttatata acgctcagga attttagcaa tctatgcaaa aagatgaaaa ttttttttgc
     2761 tcttccatta gtacacattt tttagctgaa gctgtaaatt tcatgtctta atttttttta
     2821 gtgagctttt atactggatt tgtaagaaaa aagaaggaga ggatcacata tgtcggattg
     2881 gttggatatt gcaggaaaag tagtaattgt aactggaggt tcctcaggaa ttggaagaag
     2941 tatcgtcgaa aatttgttga agcagaatgc acaagtagcg aattttgatg taactgaatg
     3001 ccgtatacag catgaaaacc tactatcttt aaaagtcgat gtgtcttcta aaacggacat
     3061 agaagaaggg atatataaag taatgaaaca tttcaagacg atcgatggtc tagtcaataa
     3121 tgcaggaata aatattcctt ctcttctaat agatagaaat catccaaaaa gcaagtatga
     3181 attatcagaa caagtttttg ataagatgat cgctgtcaat caaaaaagtg tatatttgat
     3241 gagccaagca gttggaagaa tcttggtgca aaagggatca ggagtgatcg tgaatctttc
     3301 ttctgaatca ggattggaag gatcagaagg acagagctgt tatgctgcta caaaagcagc
     3361 gatgaacagt tttactcgtt cttgggcaaa agagttagga aagaggaatg ttcgtgtggt
     3421 aggtgttgca ccagggatac tggaagaaac cggtttgaga acacaagaat atgaagaagc
     3481 tctttcttat acgagaggta taagcgtcga acagctgaga aacggttaca gtcgaacaag
     3541 tacgatccct ctaggaagga gtggtaagct gcaagaagtg gcggatctag tctgctatta
     3601 tctttcagaa agatcaagtt atatcactgg agtcacgact aatatttcag gaggtaaaac
     3661 aagaggataa aggatagggg ggacgcacgt gacgctagta aacagatggt accaattatt
     3721 gaaattacta gtcactcaca agaaagtttc aatccaggaa gtgcaaaaag aaatcaaaac
     3781 cagtaatcaa accataaaaa aagatattgg ggagttgaat gaagaaattg ccggtattgc
     3841 aaaaatcatc caaaaaaaca aacattttga acttgaaatt tatgattttg atttttttga
     3901 tgagatcatg caaggaaaat tgaaaacagc cagtgatttc aattcggcat ccaaaagaat
     3961 cgcttattta ctaaataggc tgatcgaaac agaggatttc ttacgtatgg atgatttgtc
     4021 tgaagaagtc ggtgtcagca gaggaacagt ggtcaaggat ctaaagacat taaaagagat
     4081 gatcaatgat tttgatgtaa agattacagg cacaccaaat aaaggactaa gaataatagg
     4141 agatgagcta gaattacgac tacttttatt ttattttgtt tctccctact tttcagagac
     4201 gaaaacagaa cagtttctag aagaaaaaca agcaatcaaa cattttcaga agaagacgaa
     4261 tgctagtaaa caagaaatca cccttttaac gaaagttatc ggtatttctt tgaatagaat
     4321 ctctagtaac tatctgttga agaagcccat caatcgttac agtgggtgtt ttgaatatat
     4381 ccaagaattc aatgaactga tcaatcagtt ggaagaaatc tatgaactaa ctttgagcca
     4441 atatgaaaaa gattttatca gttttccttt gaacatcatc aacacaagta taacgatgat
     4501 aaggaaagct aactctgatt tgcgcttata tttcgacccc atgatgatgc gtattcgacg
     4561 attagatctc attgatctgg atgagtcctt cttatatcaa gagatgaaac agcacctctc
     4621 tttattgata aatcgggtaa tttttcgtta tcgattgact gatttatttt atggtgagat
     4681 agaaaaaaag tatccttttt cttaccaaat cgctagcgaa tgcatacaag cattagaagc
     4741 tatcttgcaa cataagatct ctaaagtaga gatcagctac ctaacgttgt atttggagtt
     4801 agcatttcga tatcaaaaag agcatttttc ctctaaaaaa gtagccattg ttcatacgac
     4861 aggaaaagga acagcattaa tgatccaaag acaaatcaaa aggatattgg ggagggatat
     4921 acaaataaca catgtttcag aagaacaata tgaaaaagta gatctaaaca aatatttcgc
     4981 tgtttttaca acgattccgt taaaaaatgt aaatgaagag acaccggtga tccatttgac
     5041 taatcttttt gatgactctt ggttaagggc acaatggcaa aaagcaaaaa aaaagcgatt
     5101 agccgggttt cattctactg tttttttcta tcaaatatgg aaagaaaaaa agacgtatca
     5161 agaatattta aacaaattag tcgctccttt gatcagaggc tattatgtgg atgaagaatt
     5221 tgaaaaaagg atcttgaaaa gagaatatca gcaaagcaca tttgttaaca aagaatttgc
     5281 ttttcctcac acaaccaacc agctatctca acacattgtt ttatcagtag ggctaataac
     5341 tgatcaaggt ttagcagaaa caggaggaaa tgcagttatt tttttatttg ccatacctga
     5401 agaaatgacg gctgaagttg agaatgaatt atttgagcta tacgatatcc tatttgaact
     5461 cataaaaatg ggaatagatg agtttattga attagcaccg acacaagaat catttttaaa
     5521 actaatcaaa agtaaaggag agagacttca tgaatgatat gtatctattc atagttttcg
     5581 cagcttcagc ttatgtgctg caagcagtta tcagttggaa gcaactaaag catttcaatc
     5641 aaacatatag cgaactgcga agaaaaggaa aagtagcgat tggtaaacga cctgggaaaa
     5701 tccgttcagg cacgattgtt atgctagcta tagacgatca tgatcaagtt ttagaagtca
     5761 gaaaaatgca aggggttaca tctttggcaa aatttcattc attacctgtc tatgcgggtg
     5821 aagatatcca ttacatcgat cgttaccatc cctcagttcg agcggaagat cgtttgacac
     5881 aagcagcttt agaaaatgcc agagaagtat acttacgaat agaggcagga aatgaaaaaa
     5941 gtgaacaacc ttcattgcct tttattgcta tgctcaataa ttttcggata tggaaaagta
     6001 cgatcaaaga aaaaaggagt gacaaacgat ggatatcata acaaaatttg ctgagggatt
     6061 tatgaggctg ttccaaacag gtgcagaaac attcataagc tggatgacag gaatcgtacc
     6121 agttgtcttg atgctgatgg ttgcaatgaa tacgctgatt gcttttttag gtgaagaccg
     6181 agtaacgaaa gtagccaaat tatcagcgaa aaatccgctt actcgttacc ttgtgttacc
     6241 gttcttatct gcttttatgt tgggaaatcc tatgtcattt acaatggctc gtttccttcc
     6301 agaatactac aaaccaagct attatgctgc tcaagctcaa ttttgtcata cgagcaatgg
     6361 tgtattcccc catattaatc ctggagaatt gtttgtatgg atggggattg ctcaagggat
     6421 cgaaacctta gggctaaatt cgatggagct ggctatccga tacttgcttg tgggactgct
     6481 gatgaacttt attggtggtt ggataactga ttttactact ggatttgtat gcagacagca
     6541 aggaatcgtt cttagcaaaa aagtagagct ttcagttgat tagagaaagg agagttttaa
     6601 atgtatggtg atattaagat cgtaagagga aacggcgggt atggaggtcc tttgattatt
     6661 aggccgacaa aagataaaca caagttcatc tatgtcacag gtggaggtga gaggccaatg
     6721 atcgtagata aaatagaaga actgacaggt atggagtcta tcaatgggtt caaaacatca
     6781 atacctgata gtgaaatcgc gcttgcaatc gttgactgtg gagggactct tagatgtgga
     6841 atttatccta aaaaagggat accaaccatc aatatcgttc ccacaggaaa aagtggccca
     6901 ttagcacaat atatcactga agatatttat gtttcagcag tagggttaga acaaatacag
     6961 ccactaatgg aaactgatga taacaaagaa acagtaaata ctgcatctcc agataaaaag
     7021 tacaaatatg atacttctaa aaagataacc gagcaaaaag cagagcagca aaactggata
     7081 gcaaaaattg gaatgggcgc gggaaaagta gttgctacat tcaatcaatc agcaagagaa
     7141 gcagtagata cgatgatccg gacagtgatc ccttttatgg ctttcgtttc ccttttgatt
     7201 ggtgtgatac aaggttctgg gatcggtaat gtatttgcta acattatggc acctttagca
     7261 ggaaatgcag ttggattaac aatcattggc tttatttgtt cactgccatt tttatctcct
     7321 ttgcttggtc caggggcagt tattagccaa gtgattggaa cattgatcgg tgtagagatt
     7381 gggaaaggaa atattcctcc ccaattagca ttaccggcac tatttgctat caatactcaa
     7441 aatgcatgtg attttattcc agtcggtcta ggtttggaag aagcaaaagc tgagacagta
     7501 gaagtaggtg taccatcagt tctttattca agatttctta acggcatccc acgagttatc
     7561 attgcttggg tagcaagttt tggattatat agctg
//
LOCUS       DAFEIE010000093         6901 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFEIE010000093
VERSION     DAFEIE010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.098"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            1..345
                     /locus_tag="LP345_002555"
                     /pseudo
     CDS             1..345
                     /locus_tag="LP345_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
     gene            361..510
                     /locus_tag="LP345_002556"
     CDS             361..510
                     /locus_tag="LP345_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761304.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            591..1187
                     /locus_tag="LP345_002557"
     CDS             591..1187
                     /locus_tag="LP345_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL1761305.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPEKTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            1200..2099
                     /locus_tag="LP345_002558"
     CDS             1200..2099
                     /locus_tag="LP345_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL1761306.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            2102..2233
                     /gene="ssb"
                     /locus_tag="LP345_002559"
     CDS             2102..2233
                     /gene="ssb"
                     /locus_tag="LP345_002559"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1761307.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            2255..2587
                     /gene="ssb"
                     /locus_tag="LP345_002560"
     CDS             2255..2587
                     /gene="ssb"
                     /locus_tag="LP345_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1761308.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            2632..2865
                     /locus_tag="LP345_002561"
     CDS             2632..2865
                     /locus_tag="LP345_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761309.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(3024..3146)
                     /locus_tag="LP345_002562"
     CDS             complement(3024..3146)
                     /locus_tag="LP345_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBL1761310.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            3336..3560
                     /locus_tag="LP345_002563"
     CDS             3336..3560
                     /locus_tag="LP345_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761311.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            4003..4209
                     /locus_tag="LP345_002564"
     CDS             4003..4209
                     /locus_tag="LP345_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL1761312.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            4209..4460
                     /locus_tag="LP345_002565"
     CDS             4209..4460
                     /locus_tag="LP345_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761313.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            4476..4631
                     /locus_tag="LP345_002566"
     CDS             4476..4631
                     /locus_tag="LP345_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761314.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIE"
     gene            4641..4913
                     /locus_tag="LP345_002567"
     CDS             4641..4913
                     /locus_tag="LP345_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761315.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            5358..5537
                     /locus_tag="LP345_002568"
     CDS             5358..5537
                     /locus_tag="LP345_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761316.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            5596..5952
                     /locus_tag="LP345_002569"
     CDS             5596..5952
                     /locus_tag="LP345_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761317.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT         2469 a         1114 c         1369 g         1949 t
ORIGIN      
        1 ccacttttct agccaatatc caaaaatttg tctctcactt attggaagtc gtaccagggc
       61 aaatccaatc cactgatttt ggatcgacgt tacaagaagt gaaagcagcc agtgaaaagc
      121 aagaagccgc gcgtcattta ggaatttgtc caaaatgcca ggaacaagaa gtcttactct
      181 atcaaaaggt ggcagcttgt acgtctgaag cctgtgattt taaaaggtca gaagggttca
      241 tttgaagcaa cgattgtttt aaaagaagac ttcactacag gctttgaatt ttctgaaaag
      301 aaaaaaacga acttcaagaa aagaacacgc cgcactgcaa aataatggag ggttaatctt
      361 atgcgtaata ccacacacaa acaacaagaa atcgaaaatc aaaaagccaa aattcgttca
      421 gaacaggaaa aaatgcgtgc cagcaaacga agactgcagc aattgaagaa ccagcagagg
      481 attcaaaaag aaatcgaatt agatcgataa aatcttccta actattgtat acgtataaac
      541 ttatgttata ctgtttttat aagtttatac gtatacaaag gagggagaaa atgacaaaag
      601 caatggtata caagctgcta gaagaattta atggaacttt ggctttgaag gatgccaaaa
      661 aagcgggcat ttctcctgta acgatcaaac gtatggtaga tcgaggggag ctggatcgag
      721 agtatccagg ttttttcacc ttacctggtc aatttcctga tgaattgttt atggcgcaaa
      781 aaaaatatga acgcggcatt atttcacata ttaccgcgtt agatttgtat gatttaacag
      841 atatgatccc tagacagatc gatctgactg taccttacgg ttatcacgtt tctgaaaaag
      901 gattgaagga attcgcagtt gagctacact atacaaaagc ggaatggtat gaattaggta
      961 agattgaaat aaaaagtcgc tatgggaatc ctattatagc ttatgatcca gaaaaaacct
     1021 tgtgtgacat ttggaatccc tggtataacg ttgaggatga aatcaaagta aaagcaatca
     1081 aaaactacat ggagtcggac agaaaaaatc ttagaaaatt gaatgagtat cgacgaattt
     1141 tgcctacaga taaaacgatg cgctcttata ttatggcttt aaattaaagg agaatacaca
     1201 tgacacctac gcaattaaaa gcaaaagtga agaatatttc tagagaaaaa gaagttgatc
     1261 cgcagcttgt tttaagacat tttatgatgg aaaaattctt ggaaaaaatc tcagagtctc
     1321 cttatcgtga aaattttgtg ttaaaaggcg gcttcttaat tggctcaaag tatggcattg
     1381 aaaatcgaac aactaaagac attgatacga ctttacggga aatgaaagta accaaagaaa
     1441 cattgacaac ggttctaaac gatatttttt caacgccgac gaaagaaggc attcaatttg
     1501 agattcaagg aatgaaagaa acgagggaag ctgattatta tccagggttt agcttacgtg
     1561 tactggcaca tttggaaaac atgcggccag attttaaggt agatgttact acaggtgact
     1621 cgatctatcc tgcgacgatc actcacagtc ataaattgat gtttgaggat cgaacgattc
     1681 ctttggaatc ctatcctaca gaacaaatta ttgctgaaaa attaagtgca acctttgatt
     1741 ttttaacaga taattcgaga ggaaaagatt tttatgatct ctatactatt cctaaaatgg
     1801 agaagatcga tgagaagacc ttgaaagata gtgtgagaaa tacatttaca cgtcgaggaa
     1861 aaactgatcc gttaaagata tactatgaaa aggatatgga tgtactgaaa aatagtcacg
     1921 agctaaaaga tacctggaag aaatatcaaa aaagcaatcc ttatgctgcg tcgatcacgt
     1981 acgatgagac aatggattcg attagtaatt tgatggaaaa agtgattcac gtcgaagaaa
     2041 aagagcgaaa actagcttat caaagacacc aacagatgaa tagagaaatg gagagataaa
     2101 gatgattaat aatgtgacat tagtaggacg cttaaccaaa gatcctgatt tacgttatac
     2161 cgcaagtggt actgcagtag cgacttttac cctagccgtc aaccgaaatt tcacgaatca
     2221 aaacggcaat tgagaagccg attttattaa ctgcgtgatt tggcgcaaac cagcagaaac
     2281 aatggcgaca ttagctaaaa aaggtagctt gattggtgta gttgggcgga ttcaaacgcg
     2341 gacttacgac aaccagcaag gacaacgtgt atatgtgact gaagttgtag cagataactt
     2401 tcaactatta gaaagtaaag cagcgacaga gagccgtgcg cacgctgatc aatcgtccac
     2461 cagtccaagc accgccacct ttgaacaacg gaatacagcg acgcctaaca acaatggatt
     2521 gaacgcttca cagaatccat ttggtggaca atcaatcgat attagcgatg atgatctacc
     2581 gttttagttt gagaaagaag gagtaagcat ggcaaaaaaa ttagtctgac gatggatcta
     2641 ttgatacccg taattgcatt tatagacggg atttctttgg gcgtcactga aaatcctttg
     2701 gtaaatagaa ttgcgaaagg atcactattt cttgtattcg tgtatcttgt ctgttcttat
     2761 cttttaaaaa gagcaggaaa ggataattcc ttttggcgat tgactaaagt cacagtagca
     2821 gcgacagctg ttatacttac ggctattcta ccgctttata tgtagagtta acgggaaatc
     2881 gttgaacttc ttgcgaaata ttgctataat gaacatgaaa aagaggagtt gcgctaacaa
     2941 cccctcatta acagcaccga ttaaagaacg gtggcagaat attagttatt tggaaataac
     3001 cgctgacctg ctaaagtaga cggttatttc tttttgtcat ttttaagcat atttacaatc
     3061 aaactaatca aagcaatggt aaacatacca aaaccaagaa tggtttgaat tgtctcatat
     3121 gcggacaaaa ggcttactcc tttcatagat tttagcactt acattcataa gcaccaccac
     3181 ctttccagaa gtcgccaccg tcttcaaact ttactgtctt gactattata gcatatctaa
     3241 aatcgaataa aaattctcaa ttttagctgt ttttgctata attttagcga ggtgatcgtg
     3301 atggaacaat atattggttt actcgataaa ttagggtgat caagacacag ccattgcttg
     3361 tgcgatttac attacgcacg agtcatgaac caatcaattg tgtagtggcc aatatagaaa
     3421 tagcggataa attgctgatt ttggaagaag gcaagtatac tatttcagtg acaggtcact
     3481 tcaataaacg aaagcaacta gtcattgaat caatgcaaat tagaaaccct gatcatttta
     3541 cgcgatcgat gagcatataa aagaagagct gcagtcctaa atgaggattg tagctctttt
     3601 tgttttacat agaaacagta aaaatgaaaa ggcctgttta ggaaggcaca agcgccttct
     3661 caattgaaag acctttctct cactccaacc gccaccgccg ttcgagaaga aaggaagtga
     3721 acgctacgcg ttcactaaga taaagggtct tgcatagcaa gacaaaatag aaaaaatttc
     3781 ctctcaccaa aaggttcgct cctgttcgtt atctctttat tgatttgtca gaccggcaac
     3841 aagttgcctt ttatcaccaa aaagcgacaa ggacaagggt aaatggcacg ctgcgcgccc
     3901 ttgtcttgtc gcttttcgtt gattcattct ggccaacaaa tcaataaaga aagaactaac
     3961 gaaaggaagt aaaacctttc ctaagaggag gcagaatcaa tcatgcgaaa gaaatttgat
     4021 tattggggtg ttcccttcag cgaattattc ccaaactatc atgcaccaca tactgtcgaa
     4081 tgcgattgtg gagaaagagc gaaatgtatc aaaagctatt gtttgtatca atgtccaaca
     4141 tgcgggaaaa aatatacctt gtcttatggc gattatattt taattgatga gaaaggaaag
     4201 aaacgctgat gaaaacacaa cacaaattat tgactgtaaa agaagtcgtt caaattttgg
     4261 tggacaaaga agtcatttct gaaaaagtag cagaagtttt acttattccg cggtactgga
     4321 cgatagaaac ccctttagta gaggatgcac cgactatgct atttgaagac ctagtgaaga
     4381 ttgcaggata tgaactgcat tatcaagaaa acttggaaac ttatgaaaac gaatattggt
     4441 taaccaaatt agagaactaa aaaggagaaa aaaatatggc tcaaaattac tatgacgaat
     4501 ttgtcaaatt acctttggat aaaatggcac aaaaaatgga ggatatgacg ttcctataca
     4561 acgaaacacg tgttccaaaa aaacattata aagaaaaatt gtcggtagct gtggaagaaa
     4621 tgattgaata aggtgtcgaa atgaatctta ttgcgacgta ctatcgaaca ctggaagaac
     4681 tgaaaaagca aaatgcaaaa tggtttttcc aagccttact atgcttggaa gtaggtgtca
     4741 aaccaagcac tattaaacct tctgaatacc aagctttaga actaacgtat gcgaaattta
     4801 tcgaaacgaa aaaagccaag actgtttcaa gtgaatggtt agattatttt gaaaatatca
     4861 ataagtatgg cgcatattac accatgaaaa aggaagacaa cgaaaatgaa taaggtgatt
     4921 tatcaactaa caacggattc catatcaacg atttgaaaga aaaaaaggtc aataatcatt
     4981 tataccgaaa agtgagaatg tgtgaaacaa ggacaaaaaa agcctagtaa ctaaggaaat
     5041 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataaa
     5101 cgggcaaagc ccgataactt aagagaaaga aggtgatcca tttgaacaag attattccct
     5161 tattgttagt actgtttgtt ggcgaaatac ttatgcgaga tagtgcagct gtacagttaa
     5221 acctcgctgt atttttggta atactggtgt tttgtttgat cttttggcgg tttgtattag
     5281 tcctcgtgag tctactattc aagatgattg cagccatatt tttcataggg ttatttcgat
     5341 gaaaggagtg agtaccaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
     5401 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtatggcaaa agtgaatcta
     5461 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatgtac
     5521 cagcgctaaa aaagtgacgt cactttttaa tttgatctat ataagtgata tcacttttac
     5581 caaggaggga attaaatgtt aaaaactaaa aagaattcgt acaaattaaa gcttagtata
     5641 ctatctatta tttgtctttt aggcatgata attagtggtc atttgtatag agtggcatat
     5701 acgcagttta ttgagtacaa ggttcactct ttaggattag ctggggatcg atacgttgaa
     5761 tatgtccatt attcattaaa atgttcttca tatattcttc tttggcttat tttttcattg
     5821 tttgaattgc taaatttaat agcaatatct tcatatcact tagataagct aaataccaaa
     5881 tctagccgtt ataacgaagt gtttaaggaa aatgtgaagt tagaaagtga cttaaacaag
     5941 ctaaaaaaat aaaaagaaga aaacataagt taactaaaat tattttatta agaatgatgg
     6001 aatataagga taaggttacc aacataacga tcattacttc tctgatatgc tatggacttc
     6061 tatcaatcag tattttgtct atagattatg gagtaactat actgcaagcc ttagttttgg
     6121 ctatgcctat gtatctatct ttgtttatca tgcatgaaat atataagcta tttgttttat
     6181 caaaaaatgt agaaatacgg gtaaatattt tggtgaatag ttatcaaaaa gaactcaaag
     6241 aaagaagacg gtggcggtat ttattgaaag gatgaaaaag taggatttga catactggta
     6301 ttcagaaagt gccgtcactt ttaaaacaat ggaaaaggtg gagataagat gaagaaaaaa
     6361 caaactaaac tatcattagc agatatttaa cacagttaac cgcaactgaa gatggtgttg
     6421 ttgaatttga acaatctgaa attgcggtag tagatgatcg ttaccttaaa atgccttact
     6481 tctttgacca agcaaaggtc atttgccttt gtcactacga tggggtacgt gattttaggc
     6541 gttaaaaagt agtgattata tcaactttac gagtaaatat aaatttagac atgaaactga
     6601 attatccaat ggaaaatcat ggtttataat ctagaaaaat tatagtaatg attggattat
     6661 atatattctt tcgtattttc gtacaactgt agcttgtcaa aattgagaaa tttaaccgat
     6721 taggtacttt acatcgttat ttgggtaatt tctaaaacat gaagcttacc aacgaataaa
     6781 ctgagactat cttattaatt gatcaatata agaaaatatc tttgaggaga tgatgtacta
     6841 tgttttcgtc tatccacgat tggttaggtg gtcttttcgg cggtggaggt aaaggttttt
     6901 a
//
LOCUS       DAFEIE010000094         6676 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFEIE010000094
VERSION     DAFEIE010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.100"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            71..154
                     /locus_tag="LP345_002570"
     CDS             71..154
                     /locus_tag="LP345_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBL1761318.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            279..1016
                     /gene="erm(B)"
                     /locus_tag="LP345_002571"
     CDS             279..1016
                     /gene="erm(B)"
                     /locus_tag="LP345_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL1761319.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1186..1446
                     /locus_tag="LP345_002572"
                     /pseudo
     CDS             1186..1446
                     /locus_tag="LP345_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1609..2274
                     /locus_tag="LP345_002573"
                     /pseudo
     CDS             1609..2274
                     /locus_tag="LP345_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2310..2555
                     /locus_tag="LP345_002574"
     CDS             2310..2555
                     /locus_tag="LP345_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1761320.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2658..3527
                     /locus_tag="LP345_002575"
     CDS             2658..3527
                     /locus_tag="LP345_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL1761321.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3508..4242
                     /locus_tag="LP345_002576"
     CDS             3508..4242
                     /locus_tag="LP345_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1761322.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4275..5190
                     /gene="ant(6)"
                     /locus_tag="LP345_002577"
                     /pseudo
     CDS             4275..5190
                     /gene="ant(6)"
                     /locus_tag="LP345_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5187..5729
                     /gene="sat4"
                     /locus_tag="LP345_002578"
     CDS             5187..5729
                     /gene="sat4"
                     /locus_tag="LP345_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBL1761323.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5822..6616
                     /locus_tag="LP345_002579"
                     /note="aph(3')-IIIa"
     CDS             5822..6616
                     /locus_tag="LP345_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL1761324.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2340 a         1005 c         1393 g         1938 t
ORIGIN      
        1 ttttgtgtat aataggaatt gaagttaaat tagatgctaa aaatttgtaa ttaagaagga
       61 gggattcgtc atgttggtat tccaaatgcg taatgtagat aaaacatcta ctgttttgaa
      121 acagactaaa aacagtgatt acgcagataa ataaatacgt tagattaatt cctaccagtg
      181 actaatctta tgacttttta aacagataac taaaattaca aacaaatcgt ttaacttctg
      241 tatttattta cagatgtaat aacttcagga gtgattacat gaacaaaaat ataaaatatt
      301 ctcaaaactt tttaacgagt gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa
      361 aagaaaccga taccgtttac gaaattggaa caggtaaagg gcatttaacg acgaaactgg
      421 ctaaaataag taaacaggta acgtctattg aattagacag tcatctattc aacttatcgt
      481 cagaaaaatt aaaactgaac attcgtgtca ctttaattca ccaagatatt ctacagtttc
      541 aattccctaa caaacagagg tataaaattg ttgggagtat tccttaccat ttaagcacac
      601 aaattattaa aaaagtggtt tttgaaagcc atgcgtctga catctatctg attgttgaag
      661 aaggattcta caagcgtacc ttggatattc accgaacact agggttgctc ttgcacactc
      721 aagtctcgat tcagcaattg cttaagctgc cagcggaatg ctttcatcct aaaccaaaag
      781 taaacagtgt cttaataaaa cttacccgcc ataccacaga tgttccagat aaatattgga
      841 agctatatac gtactttgtt tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta
      901 aaaatcagtt tcatcaagca atgaaacacg ccaaagtaaa caatttaagt accgttactt
      961 atgagcaagt attgtctatt tttaatagtt atctattatt taacgggagg aaataattct
     1021 atgagtcgct tttttaaatt tggaaagtta cacgttacta aagggaatgg agataaatta
     1081 ttagatatac tactgacagc ttccaagaag ctaaagaggt ccctagcgcc tacggggaat
     1141 ttgtatcgat aaggggtaca aattcccact aagcgctcgg gaccccttgt aggaaaatgt
     1201 cctaagtgtg gcaacaatat tgtattaaaa aaatcgtttt atggttgttc aaattatcct
     1261 gaatgtaagt ttactttagc tgaacatttt agaaagaaaa aactaaccaa aacgaatgta
     1321 aaagaattac tggagggaaa agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag
     1381 ccctacaatg ccgttgtaaa aattggggaa aagggatata ttgattttat ctctttttca
     1441 aaataaacat ggggctgacc caaaagtagc tcctatatga aaaatagagg tctttccatt
     1501 tagatagtag tggaaagacc tctatttatc ttttgaaagt gaatacaaaa ataaagcaca
     1561 ctctgctata atataggtga ttaatccatt tgagagaggt gctttatcat gtatcaaaat
     1621 tataccataa accaactttg tttgcctata gatcttgaaa ttaaattaga agaaaatgat
     1681 tttgctcatg ccattgtgca gtttgttgac tctattcccg atgaagtctt tcttccttat
     1741 tatcaatcta tgggtagacc ccaatatcat cctcgtatgc tactttccat tattctttgt
     1801 gcctatattc aaggggttta ttcgggccgc caaatacaaa atatgctgat agatagtatt
     1861 cggatgcgct acttatctca agagcaattc cctaactttc gtactattaa tcgttttcgc
     1921 gttcatccga ttatgaacga tattctagat cattcatttg ttcaatttcg tgagctactg
     1981 gttcaaagtg gcttaatcag tggcagtgct ctatacattg atggtacaaa aattgaagcg
     2041 gatgcgaata aatactcttt cgtttggaaa aaaagtattt taaagtataa ggatagcctt
     2101 gatcaaaaag cccttgaaaa ctaccaacaa atggtggaaa caaaaatctt acctgagtta
     2161 atagatgatt taaaggatga actttctata gaagagattg aaaggattcg tcaatctttg
     2221 gaagaaaagg aaaatcaatt aattgaagcg attgaccaaa ccgaaacagt agaagggggc
     2281 tgacccatta ttaataagga gtggacaaca tgattgatgt aaatgagcta ttggaagaag
     2341 ctattagaga aactgaaaat ctaaatgatg gcgaagtttt tcttgttaaa gatttattca
     2401 agggatatgt ggggaatagg atacccagaa aggatcgact tctgcttgga acgttatttt
     2461 taaaccatgt tagcaaaatg aatggtaatt taaaggctat tgaaaagact tcatctaatc
     2521 agcagaggta taaaaagaca attgataagt tttaactatc ttttgtgaaa ttaaaaaaat
     2581 tataaatatg ttgagtagaa gcaaaagatt tggcttggaa tttttacagc agtgaatcga
     2641 taaaaggagc atgcttgatg gtagataata ttattaaatc agtagcagag aaattatcct
     2701 ctctgtctta tatagaaggt attgttttag gtggttcacg tgcaaggggc acccatacag
     2761 aggattcgga tatagatatc ggcatctatt acaattcaga atcatttgac ataaatacta
     2821 ttaatcaatt cgctacaaag ctggatgatg agcatagaaa taaccttgtt gtacctcccg
     2881 gagcatgggg tgattggatt aatggcggcg gatggttagt cataaacggg tatcatgtgg
     2941 atttaatttt acgtgatatt aaacgtgtgg aacaaataat gaaagataca gagcacggaa
     3001 ttgttactgc caattatcag actgggcatc cccatggtta tattagtgca atgtatcgag
     3061 gagaattagc gattagcaaa atactatatg ctaagaatga aagcttatgc gaattaaaaa
     3121 aacaggcaga aacttatccc aatgctttgc agaaaagttt agttaacttt tttatgtttg
     3181 aagcagggtt ctctttaatg tttgtaaaag caaattcggg aacagacgat aaatattata
     3241 ttgcgggtca tgtttttcgt atagtttcat gtttaaatca agtgttattt gcatgtaata
     3301 atgcttattg tatcaacgaa aagaaagcta taaaactgct tgaaactttt gaacataaac
     3361 ctgaaaaata taccgagaag gtaaatcata tttttgaagt actcggtatc tcactttttg
     3421 aatgctacga catgaccgag aagctttata atgaagtgaa tgaaattgta tcggagataa
     3481 ataacttttt aaacgaggag agttcagatg aaagaaaaca aatatgatga taatatattt
     3541 tttcaaaaat acagtcaaat gagtcgctcg cagaaaggac tggctggtgc gggagaatgg
     3601 gagactttga aaaagatgct acctgatttt aagggtaagc gtgtgcttga tttaggatgc
     3661 ggctatggat ggcactgtat atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt
     3721 gatatttctc ataaaatgct cgaagtagca aaaggaaaaa cccattttcc acagattgaa
     3781 tatgaatgct gtgccataga agatgtggat ttcccagagg agagctttga tgtaatacta
     3841 agttcgcttg cgtttcatta tgtagcagac tatgagaatt taataaaaaa gatatatagg
     3901 atgctgaagg ctggtggcaa tttagttttt acagttgaac atcctgtttt tactgctcat
     3961 ggaacacaag actggtatta taacgaaaaa ggagaaatac tgcatttccc ggtggacaat
     4021 tattattatg agggcaaacg gacagctatg tttttggaag aaaaggttac aaaatatcat
     4081 agaacactga ccacatatct aaatacactg ctttcaaata gttttataat aaatcagatt
     4141 gtggagccac agccgccaga gaacatgatg gatattccgg ggatggcgga tgaaatgcga
     4201 cgcccaatga tgctgattgt atcggcaaaa aagaagatgt aataatatag aaaaaataaa
     4261 cgaggagtat gtaaatgaga tcagaaaaag aaatgatgga tttagtactt tctttagcag
     4321 aacaggatga acgtattcga attgtgaccc ttgaggggtc acgcgcaaat attaatatac
     4381 ctaaagatga atttcaggat tatgatatta catattttgt aagtgatata gaacctagaa
     4441 ccgtttatat ctaatgatga ctggcttaat caatttggga atataataat gatgcaaaag
     4501 ccggaggata tggaattatt cccacctgaa gaaaagggat tttcctatct tatgctattt
     4561 gatgattaca ataaaattga tcttacctta ttgcccttgg aagagttaga taattaccta
     4621 aagggcgata aattaataaa ggttctaatt gataaagatt gtagaattaa aagggacata
     4681 gttccgactg atatagatta tcatgtaaga aagccaagcg caagggagta tgatgattgc
     4741 tgcaatgaat tttggaatgt aacaccttat gttattaaag gattgtgccg taaggaaatt
     4801 ttatttgcta ttgatcattt taatcagatt gttcgccatg agctgctgag aatgatatca
     4861 tggaaggtcg gcatcgaaac aggctttaaa ttaagtgtag gcaagaacta taagtttatt
     4921 gaaaggtata tatccgagga tttgtgggag aaacttttgt ccacctaccg gatggattcc
     4981 tatgaaaaca tatgggaagc attatttcta tgccatcaat tgttcagggc ggtatccggt
     5041 gaggtggcgg aaaggcttca ttatgcctat ccggagtatg ataggaatat aacaaaatat
     5101 accagggaca tgtataaaaa atacactggt aaaaccggct gcctggatag cacatatgcc
     5161 gctgatatag aagagaggcg ggaacagtga ttacagaaat gaaagcaggg cacctgaaag
     5221 atatcgataa acccagcgaa ccatttgagg tgataggtaa gattataccg aggtatgaaa
     5281 acgagaattg gacctttaca gaattactct atgaagcgcc atatttaaaa agctaccaag
     5341 acgaagagga tgaagaggat gaggaggcag attgccttga atatattgac aatactgata
     5401 agataatata tctttactac caagacgata aatgcgtcgg aaaagttaaa ctgcgaaaaa
     5461 attggaaccg gtacgcttat atagaagata tcgccgtatg taaggatttc agggggcaag
     5521 gcataggcag cgcgcttatc aatatatcta tagaatgggc aaagcataaa aacttgcatg
     5581 gactaatgct tgaaacccag gacaataacc ttatagcttg taaattctat cataattgtg
     5641 gtttcaaaat cggctccgtc gatactatgt tatacgccaa ctttgaaaac aactttgaaa
     5701 aagctgtttt ctggtattta aggttttaga atgcaaggaa cagtgaattg gagttcgtct
     5761 tgttataatt agcttcttgg ggtatcttta aatactgtag aaaagaggaa ggaaataata
     5821 aatggctaaa atgagaatat caccggaatt gaaaaaactg atcgaaaaat accgctgcgt
     5881 aaaagatacg gaaggaatgt ctcctgctaa ggtatataag ctggtgggag aaaatgaaaa
     5941 cctatattta aaaatgacgg acagccggta taaagggacc acctatgatg tggaacggga
     6001 aaaggacatg atgctatggc tggaaggaaa gctgcctgtt ccaaaggtcc tgcactttga
     6061 acggcatgat ggctggagca atctgctcat gagtgaggcc gatggcgtcc tttgctcgga
     6121 agagtatgaa gatgaacaaa gccctgaaaa gattatcgag ctgtatgcgg agtgcatcag
     6181 gctctttcac tccatcgaca tatcggattg tccctatacg aatagcttag acagccgatt
     6241 agccgaattg gattacttac tgaataacga tctggccgat gtggattgcg aaaactggga
     6301 agaagacact ccatttaaag atccgcgcga gctgtatgat tttttaaaga cggaaaagcc
     6361 cgaagaggaa cttgtctttt cccacggcga cctgggagac agcaacatct ttgtgaaaga
     6421 tggcaaagta agtggcttta ttgatcttgg gagaagcggc agggcggaca agtggtatga
     6481 cattgccttc tgcgtccggt cgatcaggga ggatatcggg gaagaacagt atgtcgagct
     6541 attttttgac ttactgggga tcaagcctga ttgggagaaa ataaaatatt atattttact
     6601 ggatgaattg ttttagtacc tagatttaga tgtctaaaaa gctttaacta caagcttttt
     6661 agacatctaa tctttt
//
LOCUS       DAFEIE010000095         6644 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFEIE010000095
VERSION     DAFEIE010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.101"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(1..859)
                     /locus_tag="LP345_002580"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="LP345_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="LP345_002581"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="LP345_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL1761325.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="LP345_002582"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="LP345_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="LP345_002583"
     CDS             complement(2143..2373)
                     /locus_tag="LP345_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBL1761326.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="LP345_002584"
     CDS             complement(2603..3421)
                     /locus_tag="LP345_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1761327.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="LP345_002585"
     CDS             3582..4271
                     /locus_tag="LP345_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL1761328.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="LP345_002586"
     CDS             4285..5787
                     /locus_tag="LP345_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1761329.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="LP345_002587"
     CDS             5800..6276
                     /locus_tag="LP345_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1761330.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="LP345_002588"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="LP345_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DAFEIE010000096         6623 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFEIE010000096
VERSION     DAFEIE010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.102"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..115)
                     /locus_tag="LP345_002589"
     CDS             complement(<1..115)
                     /locus_tag="LP345_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL1761331.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="LP345_002590"
     CDS             246..698
                     /locus_tag="LP345_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761332.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="LP345_002591"
     CDS             712..1401
                     /locus_tag="LP345_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761333.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="LP345_002592"
     CDS             1526..3877
                     /locus_tag="LP345_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBL1761334.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="LP345_002593"
     CDS             3957..4352
                     /locus_tag="LP345_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761335.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="LP345_002594"
     CDS             4677..5294
                     /locus_tag="LP345_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1761336.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="LP345_002595"
     CDS             5335..5634
                     /locus_tag="LP345_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBL1761337.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="LP345_002596"
     CDS             5668..5835
                     /locus_tag="LP345_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1761338.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6443)
                     /locus_tag="LP345_002597"
     CDS             complement(5880..6443)
                     /locus_tag="LP345_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1761339.1"
                     /translation="MIFKLRNRTEGLNIDKLFQEKASGKDTERPEFQKLLNYIREGDC
                     VIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLDTAMFDMFLSL
                     LSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLVFKTVVDMLKQ
                     GIPVAEIAKENGISRPTIYKIKKANDL"
     gene            complement(6471..>6623)
                     /locus_tag="LP345_002598"
     CDS             complement(6471..>6623)
                     /locus_tag="LP345_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL1761340.1"
                     /translation="NKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEIKV
                     LMGITA"
BASE COUNT         2255 a          943 c         1307 g         2118 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttca
     6181 tttccagtat taaaatctaa aaactgtgca tctaatattt ttaacgctac ttttttctgt
     6241 ttcataaaag caactgtatt ttttatatct tcataatctc ttcctaaacg atctagtgat
     6301 gtaacgatga cgcaatcacc ttcacggata taatttagta atttttgaaa ctcaggacgc
     6361 tcagtatctt taccactggc tttttcttgg aataatttat caatgttaag tccttcggtt
     6421 ctgttgcgaa gtttgaaaat caaacgcgcc ctctctgaac tccaaatatc ttaggctgtt
     6481 attcccatta ataccttgat ttcagtagac accgaaaagc cgaagagcgt tccatttctt
     6541 cggttctttt tatatattcc tcgaatggtc tccatgccct taatcgtgga agaggctgta
     6601 cggagacttt gataaaattt att
//
LOCUS       DAFEIE010000097         6508 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFEIE010000097
VERSION     DAFEIE010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.103"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            599..1288
                     /locus_tag="LP345_002599"
     CDS             599..1288
                     /locus_tag="LP345_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1761341.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1275..2483
                     /locus_tag="LP345_002600"
     CDS             1275..2483
                     /locus_tag="LP345_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1761342.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2777..4048
                     /gene="serS"
                     /locus_tag="LP345_002601"
     CDS             2777..4048
                     /gene="serS"
                     /locus_tag="LP345_002601"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBL1761343.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4597..6081)
                     /gene="guaB"
                     /locus_tag="LP345_002602"
     CDS             complement(4597..6081)
                     /gene="guaB"
                     /locus_tag="LP345_002602"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBL1761344.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
BASE COUNT         1983 a         1220 c         1253 g         2052 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctcttttttt aaaagttttt tcgatttcgt ttttcgaaat
      121 cttccagcaa ctcatttatc ataacttatc gtttgttatt tgtcaagaac ttttttgaag
      181 tttttttcga tagaatcaag cttcgcaagt ggttcttttt taacgactca gttatcttat
      241 catgtcattt ccaacatgtc aacaacttat tttttattat ttaataagtt attggtgttc
      301 ttttgaacaa ataataatat atcaacatca catgtgaaag tcaataagaa aatgcttatt
      361 tatcaacatt tctagcttac atgatcattg gttagttctg gtcctttttc gttcgtcttt
      421 ataactccga gagacgtaaa atccttttgt tttcagttta atgttcatgt tcttgtctta
      481 ttcacaccaa ctagatgtct caccttctaa aattttcctt aacaaagtgc tgcttttatc
      541 tatttctgct tttttttgct agaataatag taacaatatg actctggagg atttatttat
      601 gaaaattttg attgctgacg atgataaaga aatcgttgaa ttattaagta tctatgttca
      661 caatgagggg tatgaagcag taaaggctta tgatgggaaa gaagcattat ctaaaatcag
      721 aacaatccct gatattgaat tacttatttt agatatcatg atgcctgaga tggatgggat
      781 gcaagtagtg aaagagctac gaaaagaatc ccaaatacca atcattatgc tgacagcaaa
      841 aactactgat atggataaga tcaaaggact ggtcgctggt gcagatgatt atgtgaccaa
      901 gccatttaat ccgttagaag taatggctag agtaaagtct ttattacggc gtacaaaaat
      961 gcagattgcc ccagatcagc ctgatgtatt agaagtaaat gcattaatca tcaataaaga
     1021 ctctcatgaa gttaaaacaa tcgatgggaa agaaatccag ttaacagctt tggaattcgg
     1081 tatcctctac ttgcttgcta gtcatcctaa tcgagtattt agcgcggatg aaatttttga
     1141 gcgtgtttgg aaacaagaaa gtattgtctc tgctaaaact gtcatggttc acgttagtca
     1201 tttaagagat aagattgaag aagcaactgg tggtgaaaaa gtcattcaaa ccgtttgggg
     1261 agtgggctat aaaattgacg caagatagta aacgagcaac tgaaaaacgc cgtcggatca
     1321 atttgacttc aaaagaaatc agcgaattgt tagcggaagg aatcatcacg attatccttt
     1381 tgcttctatt aaatgtttct attctggttg ttatcagttc ggtgatcaac agttcacctt
     1441 ctttgacgaa tgcgatttgg gattcaaaga atatttttgc agaacgattg aacactgatt
     1501 tgttctggaa cggccggaat tttattattc cctttttctt tctattagat attggtgttt
     1561 tgtattggcg cttgattcga agatatcgcc aaatgcaatt gcggcatatc atcagcgaac
     1621 ttcactacat cgcaaacgga aattatgatc atcgtatccc ttttgaactg agtggtgact
     1681 taagccgagt ggtaacaagt atcaatggat tggtggatag taccgtagca gcgattgaag
     1741 acgaacgtaa aatcgaaaaa tcaaaagatg aattgatcac gaatgtcagt catgatatcc
     1801 gtaccccact cacgtccatc attggatacc taggactgat agaagatggc cagtatcact
     1861 cagaagaaga tcttttaaag tatacgcata ctgcttatat caaagcaaag cagatgaaat
     1921 ctttagtgga cgacttattt gaatacacta aggtacgcca gcctgctgtc ccggtgaatt
     1981 tttctgcctt tgacatgatc cagttgatcg aacagttagc agctgatttt gagttggaag
     2041 cttctaaaaa aaatatccaa atacttgttc aatcaaaagt agactccctt atcatggatg
     2101 gcgataccga aaaacttgta cgtgtcttca ataatctttt gacgaatgcg ttgaaatacg
     2161 gaaaaggagc aacgaagatc gtaatcgaag tagaacgtat cggttcagaa gttgttgcaa
     2221 cagtcaaaaa taacggagca atgatcccac aacaggcaat cgataatcta ttcgaccgtt
     2281 tttatcgtgt agaagaatct cgttcacaag caactggagg aactggactt ggtttagcaa
     2341 tcgctcaaag cattgtggct ttgcacggcg gatacattta tgcaaaatca gataagcaat
     2401 ggacttcttt catcatgcac cttccaatca agaaaaatga aaaattacct attgatacac
     2461 aggaagttat tgacgaaagc tgaaatattc gctattctta ttacaattat tagaataaat
     2521 gaaaaacaca gaacccagta cactttattc tttttcagag agctgatggc aggtgtaaat
     2581 cagcaaagga taatttggaa gttccagttc gtttacgtgc cctttcgaaa taagaaaggt
     2641 cggttcaaca gccgttatgt gttcaacaag tgcagctgac gctgaacttg ggtggtaccg
     2701 cgaatttcag actgattcgt cccaagaata atgggatgga tcagtctttt tttattttca
     2761 aaaaggagga aatcatatgt tagatgtaaa aatgatgcga caaaatattg aagaagtaca
     2821 agaaaaattg atgactcggg gcgtaaaaaa agaaacatta gctgaattca tggaactaga
     2881 tgaaaatcgt cgtaagctac tagtcaaaag tgaagaatta aaaaaatatc gaaatgatgt
     2941 ttctgctgag atcgcccaat tgaagcgtgc aaaagaagat gcttctgcta aaatcgctga
     3001 aatgaaagaa gtcggtggca acatcaaagc attggatact gaaattgctg aagtggatga
     3061 aaaattgaaa caaattgcaa ctactttgcc aaaccttccc catgattctg tgccagttgg
     3121 aacagatgaa gaggacaatg tagaaatccg tcgttggagc gaaccacgta catttgcttt
     3181 tgaaccaaaa ccacactggg aaattgcaga aaatcttgat attttagatt ttgaacgtgg
     3241 cgcaaaagta gccggtagcc gttttgtcta ttacaaagga ttaggtgctc gattagaacg
     3301 tgctgtctac aacttcatgc ttgatcagca tatttacgaa cacggctata ctgaaatgat
     3361 cactccttat atcgtcaaca gtaaagcgat gtttggtacg ggacaatttc caaaattcaa
     3421 agaagatgtt ttccaattgg agaatactga tctaacatta atcccaacag ctgaagtacc
     3481 attaactaac tattataatg atgaaatttt agatggtgca gatttaccta tttatttcac
     3541 tgcactaagc cctgcttttc gttctgaagc cggaagtgct ggtcgggata cacgaggact
     3601 gattcgtctt caccaattca ataaagtaga aatggtcaaa ttttcggatg tagagcattc
     3661 ttacgaagaa ttggaaaaaa tgacagctga tgcagaagat atcttgaaaa aattgcattt
     3721 gccttatcgt gtgatggcct tatcaactgg agacatgggc ttttctgcag ctaaaactta
     3781 tgacttagaa gtatggatac ctgcacaaga tacttatcgt gaaatcagtt cttgttctaa
     3841 ctgtgaagat ttccaagcac gccgcgcaat gatccgttat cgcgataatg atggaaaaat
     3901 ccactatact catactctga atggttcagg acttgcagtt ggccgtacag tagctgccat
     3961 tttggaaaac taccaaaatg aagatggttc tgtcacagtt ccagaagcgc tcgttcctta
     4021 tatggggaat ctgaaagtta ttaaataaag aggctgtgaa aaagccgctt agtttcgagt
     4081 attaagaaaa attttgtgaa aatggctttc cacatttttg cataaattgg acttaatacc
     4141 gagaaactgg cttttgaaca ccatttatcg agaggttgtg aaatcagcga attaacctga
     4201 gtattagaga aaaaaatgga aaaatagtcc ctcatatttt accgtttgtt gaactaatac
     4261 cgagggtcag ctgattgaac accgtttagt ggagaggtcg taagcctacc ccccagctcc
     4321 tagttacaag gacaaattca aaaaacagct cttcatattt tatgaatgtt gtacttgtga
     4381 ttcggaggtg gcaagggaac actgtttatt caaaaagagg ctgggacaga agcgtttaac
     4441 tccaagaaat aagaagaaat tcacgaaaat tgcttttcaa atttttgtga atttcttctt
     4501 atttccgaag gagttgcttc tacttccgcc gtttatacgt gtttagagcg tgagacaaaa
     4561 gtgttcttta cttttgtccc acgctcttta atgtttttaa gattcaactg aatagtttgg
     4621 tgcttctttt gtgatttgta catcatgagg gtgtgattct tttaatccac tgccgctcat
     4681 ttggataaat tgcgcttcat cacgtaattg ctgtagattg gctgccccaa cataacccat
     4741 tcctgaacgc aaaccgccga tcatttggaa aataatatct gcaacacttc ctttataagc
     4801 aacccgacct tcgattcctt ctggtactaa tttatttgct tcattgacac taccttggaa
     4861 gtaacggtct tttgaacctt tttccatcgc gcctaatgag cccatacctc ggtatgtttt
     4921 gaatcgacgt ccttggaaga tttcgaattc acctggtgat tcatctgtcc ctgccaacat
     4981 acttcctagc atcactgcat gtccgccggc agctaatgct ttgacgatgt caccagaata
     5041 tttgatccct ccgtctgcaa taatcgcttt gccatattga cgagcaactg atgctgcatc
     5101 ataaatagct gtgagctgag gtacacctac accggctacc acacgtgtcg tacaaatcga
     5161 tcctggtccg ataccaactt ttacgacatc tacacctgca tcatataaag cttttgtcgc
     5221 ttcagccgtc gcaacgtttc ctgcaatcaa tgttgcatct gcaaaagttg aacggatttc
     5281 ttgaattttt cggatcacac ctgcactatg tccatgagct gtatcgatga tgattgcatc
     5341 tgcccctgct tctaataaag cattcgcacg ctcaaatgta tcgcttgtta caccaacggc
     5401 tgctgctaca agcaatcgac catgttcatc ttttgctgca tttggaaatt cgatcacttt
     5461 ctcgatgtct ttgatcgtga tcaatccgct taaacgacct tcgttatcta cgattggtaa
     5521 tttttcgatt ttatgttttt gcaaaatctt ttctgcatct tttagagagg tacctactgg
     5581 ggcagtcact aagttgtctt ttgtcatcac atcagcaatc ggcatgtgat aatctgttac
     5641 aaaacgcatg tcgcggtttg taattatccc taccaatttt ctgttttcaa gtgtttcaac
     5701 gattggcaca ccactgatac gatatttgct catcaattct tctgcgtctg ctacaagatg
     5761 ctgtggcgtt aagaagaacg gatcaatgat tacgccactt tcagaacgtt tgacttttct
     5821 tacttcatcc gcttgctggc tgatcgtcat gtttttatgg atcacaccta gtccgccttg
     5881 tcttgccata gcaatggcca tcttgctgtc ggtaacagta tccatacttg cactgatgat
     5941 tggaatattc aacttaatat ttttagctaa ttgtacgctc atatccactt cgtttggtaa
     6001 cacgtgactt tctgctggta tcaataagac atcatcaaaa gtaaatcctt ttttcgtgaa
     6061 ctttgtttcc cagttggaca tttttagtac cactcctcta atttagttta tctattaaaa
     6121 taattgattt tttcatttaa gtcaatgatc tacttggaat caagttagct ttctcataga
     6181 ataccaatat aaagcgttta catctgtgta tattaaaaga gattgtaaaa aagctgtcct
     6241 gcatcaagta ataagaacag ccaatcaaaa acagcttctc atgtttttga attggttggg
     6301 tttattaccg cagatgcaaa cttttgaaca ccgtttagtg gagaggctgt gaaaaagctg
     6361 cttagtttcg agtagtaaga aaaattttgt gaaaatggct ttccacattt ttgcataaat
     6421 tggacttaat accgagaaac tggcttttga acaccgttta tcgtaaaaag ggactgtgac
     6481 aagacttttg tcacagtccc ttactatt
//
LOCUS       DAFEIE010000098         6466 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFEIE010000098
VERSION     DAFEIE010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.104"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(109..564)
                     /locus_tag="LP345_002603"
     CDS             complement(109..564)
                     /locus_tag="LP345_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761345.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(718..1926)
                     /locus_tag="LP345_002604"
     CDS             complement(718..1926)
                     /locus_tag="LP345_002604"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBL1761346.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2038..2370)
                     /locus_tag="LP345_002605"
     CDS             complement(2038..2370)
                     /locus_tag="LP345_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL1761347.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2518..3393
                     /locus_tag="LP345_002606"
     CDS             2518..3393
                     /locus_tag="LP345_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1761348.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3475..4056)
                     /locus_tag="LP345_002607"
     CDS             complement(3475..4056)
                     /locus_tag="LP345_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBL1761349.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4062..5321)
                     /locus_tag="LP345_002608"
     CDS             complement(4062..5321)
                     /locus_tag="LP345_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL1761350.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5323..6369)
                     /locus_tag="LP345_002609"
     CDS             complement(5323..6369)
                     /locus_tag="LP345_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761351.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1802 a         1338 c         1102 g         2224 t
ORIGIN      
        1 aaatcttgtc acagtccctt attctgaata aacggtgtgg aagagacagc ctatcagtag
       61 taataagaca catctctttc acagcctcat ttttgcgtaa aaatcgattt attcgaaaaa
      121 ttccccgtat acatcttcta cacgttgatc tggattgatc acgatataca agttacctgt
      181 tttttcgctg atttttgttg attgatattg attgtctaat ccttctgttc ctttatctag
      241 atatgggaag tacacaagat caggtgtgcc atttcggtaa aggatttcca ttcgctcgat
      301 atcttcgtat ttcaatgcgc gattaaacat gcccatttcc agtccgccta ggttgatatc
      361 atgtgtcgca actgcgtccc cttcatggaa gatttcgatt ttaaatccag cacacggatg
      421 gatttcaaca aattcactgc cattgattcg tccaaaactt gttgtgattt gtttgatcca
      481 aagatcgccg atatgacggc ggttgatcgt ccaggtttct ccatttctaa aataaaattt
      541 tagcgctgtc atttctttac tcattaaaaa gactccttta tgatgtaatt tattcttgta
      601 ctacctcagt ttagcacaaa tttatgtaag tggtcacatc ttatgttttt tcttctaatg
      661 acgtatctgc ccactttaag tagccaacaa agctgagcag atacagtcta gtgtttttta
      721 aatcaatttt tctttcgata aaaaatccaa aacctgtttt ttatcatttt ttattctttg
      781 ttctacgacg gctttttcag ctaattgcaa agcttcacta acccacttac caggtttttt
      841 tccagtttct tctagcaaga ttttaccatc tactgctaat tcgcttaatg acttgatagg
      901 taaacgatca taggattctc ctacggcatc catctgaggt gtttcgtcaa aatagatcat
      961 caattcttct acttgcagtg catgtttttt gcctaagaag tacaattcga atggttccaa
     1021 agctccagtt tctcgttgtc gtagtccttg gacaagtgct tgaacgtctt taatcatttg
     1081 gttagaacac ttccacgatt tcaaaaagga acgaatctca ttttctttta gatccagttg
     1141 gctgatcaat aatgcccatg cttggctctc ttctttcaat gggacggatg gtaattcagc
     1201 aaaacgtaaa agtgcttcgc cttcttcttt caaaccggga cagcaaatgt agcactctgt
     1261 ttcaataaat gcatggattc ccgcggcccg ttcatttccc aagagcatct tgatgaattc
     1321 cacatttata cgttctacag atattttacc taatagctcg tggttttctt tgatggcgta
     1381 gaaggtttct tcctctaatt tgaaccctag ttgactgaca aaacgcaacc cgcgcatcat
     1441 tcgtaaggca tcttcatgga accgctcatg aggattgcct acagctcgca agatctgttc
     1501 ttctagatct tgcagaccat cgaacaaatc gatgatttct ccatcttctt tcaaagcaaa
     1561 cgcattgatc gtaaaatctc ttcttttcaa atcttctgcc aacgaacgaa cgaattcgac
     1621 atgatctggt ctacggtagt cctgataagt tgattccgtc cgaaatgtgg tgatctcata
     1681 ttgttcatca ttttctaata ccaacacagt tccatgttcg atcccaatat ctatcgtttt
     1741 tggaaaaagc tgtttgattt cttctggaaa tgcgcttgtt gcgatatcca catcatggat
     1801 tggctggttc agcaagatat cacgaacact tccacctaca aaataagctt catatcctgc
     1861 attctctaat tttttcagaa ctggaattgc cttttggtat tccagaggta attgttttaa
     1921 tttcattttt ccaacctttc ctgcgtgttt cttgtcctga gataaagact cagttgcatg
     1981 gtgactgttt gacaagtccg tttcagagtc ttcaaggcca ggaccacttc atcttgttta
     2041 ctcgtcctta cgctcaaagc gattatggtc tctttgattg aatttttcca tgtttttttc
     2101 aaaaacttca gttaagtcga tattcaatga attagccatg atcatcgtaa cgaataaaac
     2161 atcaccaagt tcttctgcta ccgagttaac tggttcagaa gcctttttgc ttttttctcc
     2221 ataagtgtgg ttgacttctc ttgccaattc acctacttct tcagttaatc gagccatctg
     2281 agctaatgga gagaaatacc ccaccttgaa ttgctggata tattcatcca cttcctgctg
     2341 catactgtat aaagaacgct ttttatccat ctttttccct ccaaaactat cttaccaaaa
     2401 ctttaacgca aatcctagat aagagcactt gagaaaatcg aatttccatg ctacatttag
     2461 gaaggaattt ctaaatggaa attctgtgaa aatacataat tgaaagctgg aattcatatg
     2521 gtcaaacgaa aaacagtaaa agaagttctt tttatcatta taggaacaag tatttatgca
     2581 tttggtcttg tttacttgaa catcgctaat catttagcag aagggggagt ctcagggatc
     2641 accttgatct taagagcttt atttggtatt gatccagctt atacgacttt attaatcaac
     2701 atcccattga ttttactagg aggaaagatc ctcggtaaac gttccttggc ctatactgtt
     2761 ctaggtacac tttctttgtc attcttttta tggatctggc aaagggttcc actagaaatc
     2821 aatttacagc atgatctact gatcgtttct ctacttgcgg gtttagttgc aggtgtagga
     2881 agcgggatcg tctaccgcat gggtggaaca acaggcggca gtgatattat cgctcggatt
     2941 ttagaacaaa attacggcat cactatgggg cgttccctat tggcatttga tatcatcgtc
     3001 ttacttgctt cattaaccta tatcgacttg aaacgtatga tgtatacgtt gattgtttcg
     3061 tatgttttca gtcgtgtgat tgattcgatc ttagatggcg gatattctgc aaaaggtcta
     3121 cttgtcgtct ccaacaaaag cgaagagatt gcaccactac tgatgaccgg tctgcaaaga
     3181 ggtgtgactt tcctttctgg agaaggcgca ttctctggta attcaaaaaa aatcatctat
     3241 atggtcgtta gctctagtga attaactgaa gctaagagga tcgtccacga gattgacgaa
     3301 aaagctttcc tttcaatcat caatgtgcat gaagtggaag ggcaaggctt tacttatttg
     3361 aagccacaga caagattact gaaaaaacta taagaaaaaa gacaaagata ggctatgagg
     3421 aaagattcca catccagctg acctttgtct tttttagtac tatactattt ttaactaatt
     3481 gttatgttca cttacccggt tacttttctt ttgtgtctgc aaaaggatct ttcggttaac
     3541 ttcatcagat aatttcaaaa aagcatccct atctccatct tctagtgctt gatcgatttg
     3601 agcataaagc atttttagtt ttgcctcttc ttctttttct tgaaaatatc gttcaattaa
     3661 ttcagtatct tcttcactga ctgaagaatc ccaagaagaa aatggattgt cttctaagat
     3721 agatagatat tctcttgtct gccaagcatt ttcgaatata cattccacat ataaaggctt
     3781 tttccaattc aaacggattt catgaaaaat ctggtctgtg tccgtaaatt cttttccctg
     3841 caaaaacaat ttcatgggtt ccccttcaac agatagatca ctgatctgca gtcctcgatc
     3901 cgcaaaattc gccccttcaa caaagtggac attgcttaaa atcgcttcat gattggcaag
     3961 ataattcaag atccaaaaaa cttctcttcg gctaaaagat acatgattga ccatccacgt
     4021 taaaaaattc ttcttttccc gtacatcaat tagcattttt ctcacctctc tgttaggtca
     4081 tctaataatg acagtgcctc catatctcct ggttcaagtg ttaaataata agtcaataat
     4141 tcttgcgctc ttttcagctg cccttcttct cttaagaaaa aggcatactc tttcaagaaa
     4201 tctggttcat gtgatagttc atgataagcc tgttcatagt gtacagctgc aacggtaaag
     4261 tcttctaatt cattataagc atgggctagg ttccattctg cataaggatt agcagtttct
     4321 tccatctgat tgatcacttg tatcacatct tcatatcttt catcatccaa gtaaagatta
     4381 cttaaagtaa gtaatgtttc atcttgtttg tctcctactt ctaaagcttt cagtaaaagt
     4441 tcttctgctc gctgtctatc atgcagacgg aaagcatttt ccgaggccag gtgataaagt
     4501 tcgacttggt aaggattttc tttgattcct tcttctaaca ctgtttgtgc ttcttcaatc
     4561 atttcttctt cttgaagagc ttgtcctaga tatagatata acgattgata atgcggatta
     4621 acttctcgaa gttcttccag atagttgatt gcctgctgat tttctttcaa ttgaagattc
     4681 gtaaaagcta gctggaacag tcgatcatct gtcctttctt ctttcagtgc ttcttctaaa
     4741 ggtacgatag ctgcttcgaa ttctccttgc atacttaagg attgtcctaa acgttcctgc
     4801 atcgagattc ctgaaatttc atttatcccg cttgccaaca atgtttcata aaccactgct
     4861 gcctctttga aacgatcaac tgaaaaatac aattcagcta gcgcaaactg gatcaatggt
     4921 tcatcaggaa gcaacccagc tgcttctttc aattttgctt cactcacttc agggattccg
     4981 ataacttggt acaaatcagc tatcgccaat aagctttgcg gatagtaatc actttgctta
     5041 tccacttttt ccaggtattc aaaagctaag tcgatctcat tatcttcgat tgcaatttct
     5101 gctaacggga tgttcagtcc gtcattttct gggtattggt tgatcagttg ttcaaaaatc
     5161 tgttttgctt cgatcaaaaa gccaatagcc agcaattctt cgcctagttc agctaatata
     5221 tctgctgggt cttcttttaa tgctttttct aaaaagattt gtgcttgtga caagtcttca
     5281 tctgataaag cttgcaacat tttttcgcta tttgtattca tttcaattcc ctcttatctc
     5341 actgacgatt tgttgaaata ccgtcattgt tctcaataat tctttttcgt ttggatgttg
     5401 gtatccgtct attataccta ttttttctaa aacaagtatt tttttgcttt tttctgccaa
     5461 aaaaagaact ttttccaaat actccatctt tgaaatctgt tccagccagt ggattggata
     5521 gccaagcaag tccagccaca caaaaaagtt ttttagttgg aaatcaaaag gatatgcttg
     5581 gagattccac acgaaatgaa acatcattcc taaaaatttt ttcatactag cagaaagtag
     5641 atggccattt tcggtcagat aaaaagcttg ttcaaacagt ttaccataat ttgacaggtt
     5701 ttctgcctct aattgataaa aatagatcat ttcttcgatc atcccggcaa acggccgagt
     5761 cgttaattgc tttttatttg gatagttttt atacagattt tgcaaaaaac gatgatcaca
     5821 aatcattccg caacagataa aagtcaaaaa gtcaatctgc tttccgtcca cctgccgctc
     5881 gctgattgtt tgatcataaa cgatgcgttc tggcagattg atggtttgca gcactacacg
     5941 atttggtagc tgcaaaatcg tccgctgcgg tgttaatgct cggcttagag aacggatcga
     6001 tacagggatc atccatagtg atgaatcaag ggttgtatgt ttttgaaaaa aacctgccag
     6061 atccatgatc ccttcatttc caaatccgat gataaacatg gattgatttt cgggatagcg
     6121 tttgacgaaa tcaagcaggt tctttaattc tgttaaatga ttgcattgag tgttggcaca
     6181 aatataccag tcattgtttg cttgatttgc aaataacggg ttgatcttat ctgcaaacaa
     6241 atcataatag cgctgattcg ttaaaaataa gattggctga tcaatggaaa gttctcttag
     6301 ctgactgact agcgtttctc cgtaaaacac tttcgtcaac gcatcttcta cttgataatc
     6361 aagttccata cgcatccctc ctcttcttat ttttatttta ccattagtaa gcaaattcta
     6421 gaaaagataa gagcaaagct cacctcataa cttggaaata aataaa
//
LOCUS       DAFEIE010000099         6346 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFEIE010000099
VERSION     DAFEIE010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.105"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            160..561
                     /gene="tnpA"
                     /locus_tag="LP345_002610"
     CDS             160..561
                     /gene="tnpA"
                     /locus_tag="LP345_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_045009167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL1761352.1"
                     /translation="MSEIHYGRGYVYSIQYHLVWCVKYRHDVLYGQVDIDVKQFLKQI
                     ADDNNIKIIEIESDKDHIHLLIECTPQHYIPSIVKVFKGASARLLFKKHPELKQLLWG
                     GHLWNPSYFVATVSENTEEQIRKYIQNQKKK"
     gene            573..1718
                     /locus_tag="LP345_002611"
     CDS             573..1718
                     /locus_tag="LP345_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1761353.1"
                     /translation="MLQHRAYKFRIYPNQEQEILMTKTIGCSRFVYNYFLNLWNHEYT
                     TTGKGLSYNSCSAMLPQMKRNAETIWLKEVDSIAIQSSLKNLSDAFSRFFKKQNKRPQ
                     FKSKKHPIQSYTTKNVNNSIEIRNNFVKLPKLGFVKFAKSQEPKGRILNATIRKNSSG
                     KFFVSILCEEEIVEFPKSNSAIGIDLGITDFAILSDGQKIDNNKFTSKMAKKLKREQR
                     KLSKRALLAKKKGVNLFEAKNYQKQKRKVARLHEKVMNQRNDFLNKLSTEIIKNHDII
                     CIEDLNTKGMLRNHKLAKSISDVSWSSFVTKLQYKANWYGRKIIKVDKWFPSSQICSN
                     CGHKDGKKSLEIREWTCPVCHAHHDRDINASINILTEGLRLHVMGLA"
     gene            1956..2219
                     /locus_tag="LP345_002612"
     CDS             1956..2219
                     /locus_tag="LP345_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBL1761354.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            2213..2563
                     /locus_tag="LP345_002613"
     CDS             2213..2563
                     /locus_tag="LP345_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1761355.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(2587..3201)
                     /locus_tag="LP345_002614"
     CDS             complement(2587..3201)
                     /locus_tag="LP345_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1761356.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            3515..3937
                     /locus_tag="LP345_002615"
     CDS             3515..3937
                     /locus_tag="LP345_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761357.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            3947..4150
                     /locus_tag="LP345_002616"
     CDS             3947..4150
                     /locus_tag="LP345_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761358.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            4361..4945
                     /locus_tag="LP345_002617"
     CDS             4361..4945
                     /locus_tag="LP345_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1761359.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            5114..>6346
                     /locus_tag="LP345_002618"
     CDS             5114..>6346
                     /locus_tag="LP345_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL1761360.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVH"
BASE COUNT         2261 a          962 c         1174 g         1949 t
ORIGIN      
        1 cacccgtgat tttaatcatg ggatgaatcg gattcagttg tgacctagct ttagctaggt
       61 taaacaactg acaaatataa actaaataat agtgaaatgt cttgcaataa ttgattttgt
      121 agaaatacat atattaaaat aattgcgagg tgtttttgta tgtcagaaat tcattatgga
      181 cggggctatg tctattctat tcaatatcat cttgtttggt gtgtaaaata tcgacatgat
      241 gttttgtatg gtcaggtaga tattgatgtc aaacagtttt tgaaacaaat tgctgatgat
      301 aataatataa aaattataga aatagaatca gataaagacc atattcattt actcattgaa
      361 tgcaccccac aacactatat tcctagtatt gttaaagtat ttaaaggcgc atccgctaga
      421 ctgctgttta aaaaacatcc tgaacttaaa caactccttt ggggtggaca tctttggaat
      481 ccaagctact ttgtagctac tgttagcgaa aatacagaag aacaaattag aaaatatata
      541 caaaatcaga aaaagaaatg aggtgaatcc gtatgctaca acatagggct tataaattta
      601 gaatctatcc taatcaagaa caagaaatat taatgactaa aactattggc tgttcaagat
      661 ttgtctataa ttattttttg aatttgtgga atcatgaata tacgactact ggaaaaggat
      721 tatcttataa ttcttgttct gccatgcttc cacaaatgaa aagaaatgca gagacaattt
      781 ggttaaaaga agttgacagt attgcgattc aatcctcatt gaaaaatctt tctgatgctt
      841 tttctcgctt ctttaaaaag caaaataaac gaccacaatt taaaagtaaa aaacatccta
      901 tacaaagtta tacaactaaa aatgtgaata atagtatcga aattagaaac aatttcgtaa
      961 aactacctaa gttaggattt gttaaatttg cgaaaagtca agagcccaaa gggcgaatct
     1021 taaatgctac gattcgaaaa aattcgagtg gtaaattttt tgtttccatc ctgtgtgaag
     1081 aagaaatagt tgagtttcct aaatctaatt ccgctattgg aatcgacctt ggtataactg
     1141 attttgcaat cctttctgat ggtcaaaaga ttgataacaa taaattcacg tcaaaaatgg
     1201 caaaaaaact caaacgtgaa caacgtaagt tgtcaaaacg tgcattacta gctaaaaaga
     1261 aaggcgtcaa tctctttgaa gctaaaaatt atcaaaaaca aaaacgaaaa gtagcacgac
     1321 tacatgaaaa agtaatgaat caacgcaatg actttttaaa caagttgagc acagagatta
     1381 tcaaaaacca cgatattatc tgtatagaag acttaaatac aaaaggtatg ttgcgtaatc
     1441 ataaactagc aaaaagcatt tctgatgtgt cttggtctag ttttgtgact aagttacaat
     1501 acaaagctaa ctggtacggt cggaaaatca tcaaagtaga taaatggttt ccatctagtc
     1561 aaatctgttc aaattgtgga cacaaagacg gcaagaaatc tctagaaatt cgagaatgga
     1621 cttgtcctgt ttgtcatgct catcatgacc gagatatcaa tgctagtatc aatattttga
     1681 ccgaaggtct aagattacat gtcatgggat tagcttagat ccaatcatca aaaaccgtag
     1741 gaactacggg gatagcttgg taaataagag aaaccgctgt gagtaaagaa atacgcttgc
     1801 aagtatgctc tattcccaag aatctcgtga ctttagtcat gagaggttca aggattcatg
     1861 gaatgttaat ctaatttaat agaaaaggat aattaagtat atacgttttt tcttatgtat
     1921 gttatactat gtatatacag aaagaggtgt ctactatgga aatgttacct ataaaaaaat
     1981 ggggaaatag taatggcctt agattgccaa agtatattat ggaatatctt ggaattcata
     2041 cagaagacaa agtgaagata atacaagaag aagtaaacgg tcagaagcgg ctaattatcg
     2101 aagcggctaa tatagaaaat gaattaacaa ttgaacagtt atttgaaaat tacactgatg
     2161 aaagaaatca tgtgacgatt caaaatttag gtgaagcagt aggtaatgaa aaatggtgag
     2221 aaaacctaga caaggcgata ttctattatt gaatacagca cctcgatctg gacacgaaca
     2281 gacaggtaaa agaccttata ttgttttaag tcatgatatt attgcggatt atagtaacgt
     2341 tgttacagtt gctccaattt ctagtacaac tagaaactat ccgctatatg taaatataaa
     2401 ctcagaatat gaaatgaaga caacaggaaa agtattatta gatcaactaa cgacaattga
     2461 ttatgaagcc agagagtgta tttttttgga aaaagcgcat gatagtttag ttgaggagtt
     2521 attgatgaaa gttagaacag tttttcaaaa agtaagcaaa taaaatagaa acagcagcat
     2581 gatcaactat tcgtgattga ccatgctgtc tttttttatt ctatatacgg tttgtctcgt
     2641 aacattgtag tcttttgcaa tcttagcgat cgcaacacct ttttttagat cctcaacgat
     2701 gtttttataa acaagacgac gttggggatc ttttgcattg gcactgtata gcttaggacg
     2761 tcctttataa acaccgttcg cttttgcaat cttaatgcct tgtgcctgac gtcgtttaga
     2821 ttcggtacgt tcttgttcag cgatcatggc caaaatttga atgatcaaat ctttaatgaa
     2881 tttatccagg agaggattgc caattgcttc ggccatgatc ggtagacttg tgatgatcag
     2941 ctgcacattt ttcttcttca agtaattgac tgaagcgatg atctcgtcgt aatttcttcc
     3001 aagtcgatca atagcttcca caataaaaat atcttgatct cggacgaaat ccagtgcttc
     3061 ttgaaaaaca ggtcgatgag taatcgttgc gccagattgt ttctcaatga aaattctctc
     3121 tgcaccgaat tttttcattt cttcaatctg ccgttgttca ttttgatcga tggatgagac
     3181 acgtatgtat gcaactctca aaatttttac ctactttctg caactattta aaaaacaccc
     3241 taatcataca cgagaaaacc agatttttca atgtcgcggt cgtgtctagt tagggtatac
     3301 cttatataga caaaaactaa tgatggagga aatagtatgt gtcacttttc tttttaaatg
     3361 gcaatatttt ttgtaaataa atgtcaatca agaaaattta aacgattatg acattaaaaa
     3421 tatattttat gaattttcta gtatataact tgatttatct gttaagattt attaagaaaa
     3481 cgttttctta tttttgattt cgaggtgata gacaatgaaa aataagttta ttttatcttt
     3541 aggtatttta actattggaa ttagtgtaac tggaactaca attcctacat ttgctgatag
     3601 tacaaatgaa ccaactactg tagtagataa taaccaagaa ttaactcctt tagataggaa
     3661 cggaatagcc attggtaacc caactaacga cttaactgtt actgaaaatt atttaatagt
     3721 ttctccatta cttgctcgag cagcttctaa aacgatacga gtgacaggaa cgatgatttt
     3781 tgataaagtt ggttggcctt ctagacctcc tcaatcacgg aattggaaag aaaaaagaaa
     3841 tggttattgg tactatggaa aattgtattt acaaagttat aaatcagctg gaaacaattg
     3901 gattgcgact tattcaggaa ccttaactag aaagtaggga ttttttatgc cagaatttgt
     3961 gaacacacca aatttttatc aagatagcga tattctaagt aaaattaatt taccgaaaga
     4021 agaatcagct ttacaagttc agcgaacttt acaggagaca caaaaaattc aaaaatcaat
     4081 ttctaatcta gaagattctg aagaaaaaag aaaaaaaaga gaccaaaaaa catatcaaaa
     4141 agaaaaataa tgattttaaa aaaagagtgt ctagtcgaca ttcttttttt ctaattgaaa
     4201 gtgttcataa aatcacccat ttctggacac tttctttttt tgctttattt ttcaaaaaaa
     4261 caattcattt catgttcata aacccataac aatatctatg ttcagttaaa ctatatggat
     4321 aaagttatgt tacaataaaa ttaatgaagg agtgattttt ttgaaaatag gatacgcccg
     4381 ggtatctact ggtttacaaa atttggattt acaagaagac agcctaaata aatttggttg
     4441 tgaaaaaatt tttactgatc atatgagtgg ggcaaaaagt aatcgaccag gattagaaat
     4501 ggccattgat tttgttcgct ctggcgatac acttgtcgtt tggcgcttag atcgtttagg
     4561 tagaaatatg gaagatttga tttcaatcgt caatcgactg aatgagcgtg gtgtgagttt
     4621 tcatagtatt caagaaaata ttacgatgga caaatcaagt tctacaggac agctcatgtt
     4681 tcatttgttt gcggcatttg cagaatttga gcgtaatttg atcctggaac gatccgcagc
     4741 aggacgagca gctgctcgtg caagaggacg gtttggtggt cgtcctgaaa aattgtctga
     4801 acaagatttg gaattactga agactttagt ggatagcggt acacctatta agactattgc
     4861 ggaacggtgg aacgtctcaa gaaccaccat ttatcgttat ttggcaaaaa tggaggagaa
     4921 aaatggaaag acaaattctc attagttttt gtcatttaat gctgaaaatt tttgccattt
     4981 atctagaaaa gtgacaatag tatgagaatt ttttgtaagt gtctactgat aacttattct
     5041 caaatattta gctatttctt ctttacaaca tcgaacatat gtttgtataa tgtggaagaa
     5101 tggagtgtta tttatgatgg attattcaaa agagccagta aatgattact ttttaatcga
     5161 tatgaaaagc ttttacgcaa gtgtcgaatg tatagaaaga aatttagatc cattaacaac
     5221 agaacttgtt gttatgagtc gatctgataa tactggttca ggattgatat tagcttcttc
     5281 tcctgaagca aaaaagcggt atggtattac aaatgtgagt agaccacgtg acttaccaca
     5341 accatttcct aaaacactac acgttgttcc accacgtatg aacctatata tcaagcgaaa
     5401 tatgcaggta aataatattt tcagaagata tgtggctgat gaagatctac tgatttactc
     5461 gatcgatgaa tcgattttaa aagtgacaaa atcactgaat ctttttacga ctgaagaaac
     5521 acgaagtcag cgaaggaaga agctcgctca aatgatccaa gaacgtatta aagaagagtt
     5581 aggtttgatt gctacggtag gcgtcggcga taatcccctt ttggctaaat tagccttaga
     5641 caatgaagca aagcataatg aaggatttat tgcggaatgg acgtacgaaa acgttcctga
     5701 gaaagtatgg aatattcccg aaatgacgga cttttgggga attggttcgc gaatgaaaaa
     5761 aaggctcaac caaatgggaa ttttgagcat tagagacctt gctaactgga atccttatac
     5821 gattaagaat agattaggtg tgattggatt acagctgtac ttccatgcta atgggatcga
     5881 tcgaacagat atagcaatcc caccagaacc gacaaaggaa aaatcatatg gaaattcaca
     5941 agtgttacca cgagattata ctagaagaaa tgaaatcgag ctggtggtaa aagaaatggc
     6001 ggaacaagta gcgatacgca ttaggcagca taactgtaaa acaggttgtg tccatttaca
     6061 cattggcacg tcgatcttag aaacgagacc agggttttca caccagatga agatccctat
     6121 cacagataat acaaaggaat tgcagaatta ttgtcttttc ttgtttgata agtattatga
     6181 aggacaagaa gtaaggcacg ttggaataac ctatagcaag cttgtgtaca ccgattcgct
     6241 tcagctggat ttatttagtg atccacaaaa gcaaattaac gaagaaaatt tagataaaat
     6301 tattgacaag attcggcaaa aatatggttt tacgtcgatt gtacat
//
LOCUS       DAFEIE010000100         6265 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFEIE010000100
VERSION     DAFEIE010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.106"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(95..667)
                     /locus_tag="LP345_002619"
     CDS             complement(95..667)
                     /locus_tag="LP345_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1761361.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(674..1336)
                     /gene="rpe"
                     /locus_tag="LP345_002620"
     CDS             complement(674..1336)
                     /gene="rpe"
                     /locus_tag="LP345_002620"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL1761362.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(1352..1867)
                     /locus_tag="LP345_002621"
     CDS             complement(1352..1867)
                     /locus_tag="LP345_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBL1761363.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(1869..2153)
                     /locus_tag="LP345_002622"
     CDS             complement(1869..2153)
                     /locus_tag="LP345_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1761364.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(2187..3515)
                     /locus_tag="LP345_002623"
     CDS             complement(2187..3515)
                     /locus_tag="LP345_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL1761365.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            complement(3529..3984)
                     /locus_tag="LP345_002624"
     CDS             complement(3529..3984)
                     /locus_tag="LP345_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1761366.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            complement(3987..5933)
                     /locus_tag="LP345_002625"
     CDS             complement(3987..5933)
                     /locus_tag="LP345_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1761367.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
BASE COUNT         2060 a         1205 c          875 g         2125 t
ORIGIN      
        1 aattattaag ttatgtctaa tcaaataaaa aaaccattct catatttgct gaataattag
       61 catttagaga atggtttttt atctttaaaa tctactactc aaaatctgca tgtcgagcaa
      121 acatcgtttc tgagctttca cctgttttat ccattaaaga taacactaaa ctatcaaagg
      181 tgagaaatgc taattgttca aaacttgaac ccataggttg tgaaaaagta tcttcttctc
      241 gttgattttc atctttggta atacctggta atacaagaac agaatctgct aattgaccaa
      301 tcgacgagtc ttttttcatg gtaactaaag caatgcttac accactttga tttgctttgg
      361 ccgctaaatt ttttaaacta cctgtttcac ctgagccaga acagataatt aataaatctc
      421 caggttgcga atgtggtgaa ctaatttcac cgacaaggct gactgaaaaa cctaaatgca
      481 ttaagcgatt cgtaaatgct tgcatggcaa ttccagagcg tcctgcacca gctagaaaga
      541 tgtgtttagc ttgaacaatt ttctcactaa attgttctaa ctctacagaa ttaatacgtt
      601 ttgagttatt ttgtaattct aagataatcg cttctaaata gtttttattt tggtctttat
      661 tggtcatgat cttttacttc acttcctcta atgattgatt tagtttatca atttgttctt
      721 gcggggtatt tttcccattg aagatgaaac cgcctgatac aaaaatatcc gcccctgctt
      781 tagaacaaac tttaatcgtt tgattatcaa tcttgccatc tacttcaata tcatacgtat
      841 aatcattttg tttgcgtatt acatctaact gttcgatttt aactactgtc tcttgaataa
      901 aatgcttatt ctctgttcct ggattgattg tcattactaa tacttgatcg actaaagata
      961 atactggttc aataaaactg actggtgttg caggattaaa agtaatccct acttttgctc
     1021 ctgcttcctt gactaactga atgaccttca ttgcgtgttt ggtagcttca atgtggaagg
     1081 taacaatatc tgctcctgct tctacaaatc ttgtgacaat tttttctggt gtatcaatca
     1141 tcaaatgaac atcaaacaca acgtctgtta gtggacgaat atctttaata acacttggtc
     1201 caaaagccat atctggtaca aaacagccat ccattacatc aatatgcaaa taatcaacat
     1261 tcttttcttt taagatttca aataactctt taacttctgc gataggtgca tttaacaatg
     1321 atggagcaat tgtcattctc tattcccccg tttattctcc cataatcatg agattgattg
     1381 ttctagttcg ctctcttagt tgatcccaat cgacaaaata gacacggccc atttctccta
     1441 ataaaagttt accttcttga acaattaaag tcattgagtt ggttccataa atagatgaac
     1501 gtaaatgtgc atcggtattt agcatgaccc atttttctgc agggtaattg ggatcagata
     1561 atcttgttcc aaaatcaatg tgttttggcc ccggactgtt gtattgattt tcactcgtca
     1621 tttttggaat aatcgtttcc attacattgt tgatgtctac atgtaaataa tcatcaccaa
     1681 aaaagtttgt gtcatgcatc gtttcttcaa aaaagagtga gcaagttgta tgcgggctcg
     1741 aaattactaa cattccattc tcaatacctg ctgtatcaac tgtatctaaa agttcttttc
     1801 gaatatcatg atacgaagga cgccctgaaa ctgtttcaat agtcaaagtg tcatgatgaa
     1861 aacgcatatt aaacacctaa tctttctttt acatctgcat aaatggcatc tgtaccaata
     1921 cctgttaata agcccaagcc attcgttact ttagctttaa ttacatcagg gacaattgtt
     1981 gtacttacta cagcatcata ttcatcaatt ttatttagct catcagcaat tttagattga
     2041 taaattttca cttgatctgt taatccttct tcttccaacc attttgataa ttttgctact
     2101 gcaattgtag aagtagcatg acctgctcca caaataacta ataatttttt catattgatc
     2161 tcttctttct tattttaatt ttatgattaa gctttcttca ctttgttcat gtagatagaa
     2221 gcacctacta aaacaactcc taatccacct attccaatta caccaaagta agatgctaat
     2281 aaaacaaaca accctactgg ccataatcca cataacaaca tagttactaa tcctgctgtc
     2341 cccacatcga aacttgctaa tgtaaacaca tcagtgataa ttggtgccaa ccatgttgcc
     2401 atatataatg ttgtaacaac atacaacgaa catcctacta atgatctcac aatatttcct
     2461 ttaaaataag gaatcattaa acagatggcg aaagcaaaga atgctaaatc tccaaaaggt
     2521 aatactttat ttcctggaag aattagtgct agcaataatg agattggtac aagcaataga
     2581 gaagttgaca taatagttgg atgacccaca gttaacgctg catccattcc aatgtttact
     2641 tggcgaccat ttaacttttt attcgtaaat tctttcgccg cttctgcaat tggcattaaa
     2701 ccttccataa acattgctac cattttaggc ataatcttca tcactgccgc agtcataatt
     2761 cctaagtttc caattcctgc tacgtcatag cctgccataa tacccactac aataccgata
     2821 attaggccaa taacaactgt gtcacctaaa acaccgaaac gttttgttaa tgtttctgca
     2881 tctgcatcta ttttattaaa tccaggaata cgatcaaaaa cccaatttac tggtttggca
     2941 aatagtactc ctgataatcc catcatatgt gtgatagaga ttcctggata gccgaaaaat
     3001 tcgctaacag ttttttgtgt acgatctgct aagaaccatt gtaaaattac tgcgacaatc
     3061 gcgccaatta agccaaacca aaagtttccc gtaacagatt gagtaatcat acctaggaaa
     3121 attgcgaacc aaaagttcca aatatcaaca ttcaatgttt ttgtccaacc caaaaccaca
     3181 aatatgaagt taagaattaa tgaaattgga atcattaaaa ttcccaatga tgtagagtaa
     3241 gccaaaggtc caccaacacc tacgccaata tctaggatat tcaggccacc accgtattgt
     3301 tcccccattt gttgaattgc tgttcctaaa ccatctgata ataaacttaa aactaatcct
     3361 aaaccaatag aaccgatacc aacagtaacg ccggaaacaa atgctttacc aggttttaat
     3421 ccaaataata tcccgattac aaaaataatc agtggtaaaa agacgtttga ccctaatcca
     3481 ataaaccatt caaaggcatt taatacaata tccatctctc tattcctcct aataaactcc
     3541 tgcagaatgt actaactcaa taaatgcttc tttcgtggta catgcaagta attcatttac
     3601 tttttcttca ttttgaaata ggctaactaa gttttgtagt gtatcaattt gttcatgagg
     3661 ttgtgacatt gccaacataa agactaaacg tacaggtatt tcatgagatt tatctgtcat
     3721 atctgaaaat accagtggtt cctttaatga ggcaaaacag atttgagagc tatttacatg
     3781 tgcggaatct gtatgtggga tagcaaaccc aatttgattt acttctaatc cagttggaaa
     3841 ttcttgttca cggttggtga taccttctaa gaaactatct ttcacgcaac cagcgttttt
     3901 taattgttca gacattactt gaaacaattc tttttgatct ttcacttcta attgaaataa
     3961 acataattct ttatctagat acatttttat tctccttttt gttgaaaaat tcttagtaat
     4021 ttttcgctat catgaacttg taacaagcga tcgaccattt ctttttgccc aataaattgg
     4081 taaagttctt catatactcc tctaatctca gatacatctt cttcagctaa actaaccata
     4141 atgactaatt tgacttttcg atcgccccaa ttaatcgcat tttttaatgc tacaataaaa
     4201 atgttggatt caatgaccat tgatggattc gcatgcggta aagcaacacc actttctaaa
     4261 ttagtattcc ccattttctc tctagagaag atagaagcac gaaactcttc agtaactaat
     4321 gaattggctt ctagttcgga aatcatcaaa tccaaacatt cttctttgct ttccacctgt
     4381 actcctgttt ttactaaaga tgattgaaca aatttagata tggtgggaac tttaaccgct
     4441 ttaggaatca gttcattttg aataaatcgc gaaggttctt ctattaaata tttagtataa
     4501 gcttccataa tattcatata atctgtttta cttaccaatg gagataccct tactaagggt
     4561 ataccacctg catcaaagga aagagaggaa ataatcaaat caacttcccc aatttcagct
     4621 aaatgaaact tatctaaagt tgatatttct acattatctt ttgctggtaa aaaccgtcga
     4681 actttattgt aaattaattg cgcagaagaa ataccgtatt ggcaaataat gatgatatta
     4741 tttgctttgg actgatcttc aatagcaatc tgaaaatgaa tcaaaattaa ggaaacttca
     4801 tcgtccgtta aagtcacatc aaattcttct tcaaggatgg acatggcgta ccatactatg
     4861 ctaaagagtt ctgaatattg agatttgata ttttctaata acggattttg aattttaata
     4921 ccttttttta aacgaaggac cattgctggc acatgataca ataaggattg atataatcga
     4981 tcattttgag tcaaatcaat tttttcaatc tcactcattc tttcaatcaa tttatgaacg
     5041 ctcatagcgt actcttcatt gctggttttt aaattatttg tcacacgatg tgcaaatagt
     5101 tgacgacata gatattcttt atctgcgtca taaaatggaa gattcaattt tgccttcaat
     5161 tcttcaatta aaccatttgc cacaatgtac gtttccatat agcgaatgct attgaagagg
     5221 aattcttctt caacagttaa atgatgacct ttcagtaaac ggttacattg gataactaaa
     5281 gtagaaatca atgaccgaac atagtaatca gaaacctttt cagtcagttc actgtaatca
     5341 ttgaatagca aatcatgaat gacactaata acttttgaat caaacaacat atttaaaact
     5401 tgaaaaaatg tttttgattc catgtcattc gcataataga atacaagttg cttgattgct
     5461 cgttgaattg cttgttcatt accagtaaaa ctaattcctt ctgcagatga ctgcaactta
     5521 acttctccac tgccaataat tttattgata attctcaggt cattgtataa cgatgtttta
     5581 ctaaccataa aactttgaga caaatgagtt aaagaaacag gcttatcacc aaacaaaact
     5641 tctttaatga tctcgacacg tcttttttct ggagaataaa tatctttttc aagataattt
     5701 tctaccgatg aaatcaaatg ttcaacgttt ttcctatcac ctatgagttt gatacccaaa
     5761 gaaggtaatc gctcaattgt tacttggtaa ttaactacat aatcttccaa caattcaata
     5821 tcttgataaa tggtcttggt cgacactgcc aatttatcac taaaaaaaga agcgggttta
     5881 aagtcttctt gtcgacttaa taattttaat aaatttacat gtctttcaat caaacttgtt
     5941 cacctcttaa cgctagcatt tgttacctct tttcattatt tattctagca ctggaacccc
     6001 cttccctcaa ttacatctat gtcaataata cttgtggaag tttgttgtaa aggaaatcca
     6061 aataatctta aaaaatgaga aacaaaaaag gagaaatcct taaaagagct aagatattcc
     6121 aatagaaaat actccttatt atggaagtaa tatgaaatat tacaattgaa aaataaaaac
     6181 aatataatgg cgtcactaaa attcgtattt ttttattata atataactta attacaaatg
     6241 ctcatctatg aacaattgag tccta
//
LOCUS       DAFEIE010000101         6173 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFEIE010000101
VERSION     DAFEIE010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.107"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            725..811
                     /locus_tag="LP345_002626"
     CDS             725..811
                     /locus_tag="LP345_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL1761368.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="LP345_002627"
     CDS             complement(932..1621)
                     /locus_tag="LP345_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761369.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="LP345_002628"
     CDS             complement(1866..2780)
                     /locus_tag="LP345_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL1761370.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="LP345_002629"
     CDS             complement(2762..3142)
                     /locus_tag="LP345_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBL1761371.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="LP345_002630"
     CDS             complement(3592..3879)
                     /locus_tag="LP345_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL1761372.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="LP345_002631"
     CDS             complement(3899..4123)
                     /locus_tag="LP345_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBL1761373.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="LP345_002632"
     CDS             complement(4578..4748)
                     /locus_tag="LP345_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761374.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="LP345_002633"
     CDS             complement(4763..5296)
                     /locus_tag="LP345_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL1761375.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="LP345_002634"
     CDS             complement(5317..6159)
                     /locus_tag="LP345_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL1761376.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAFEIE010000102         6135 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFEIE010000102
VERSION     DAFEIE010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.108"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(207..1169)
                     /locus_tag="LP345_002635"
     CDS             complement(207..1169)
                     /locus_tag="LP345_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1761377.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="LP345_002636"
     CDS             complement(1171..2610)
                     /locus_tag="LP345_002636"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBL1761378.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="LP345_002637"
     CDS             2795..4741
                     /locus_tag="LP345_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBL1761379.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="LP345_002638"
     CDS             5005..5877
                     /locus_tag="LP345_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1761380.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1947 a         1054 c         1084 g         2050 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt ggggggcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttaatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 atatctttgc ttctt
//
LOCUS       DAFEIE010000103         6085 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFEIE010000103
VERSION     DAFEIE010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.109"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            832..1566
                     /locus_tag="LP345_002639"
     CDS             832..1566
                     /locus_tag="LP345_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1761381.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="LP345_002640"
     CDS             1582..2751
                     /locus_tag="LP345_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1761382.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="LP345_002641"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="LP345_002641"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL1761383.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="LP345_002642"
     CDS             3841..4767
                     /locus_tag="LP345_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBL1761384.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="LP345_002643"
     CDS             4786..6036
                     /locus_tag="LP345_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1761385.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2030 a         1000 c         1250 g         1805 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agttaagtat cgccgtttgt ataat
//
LOCUS       DAFEIE010000104         5899 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFEIE010000104
VERSION     DAFEIE010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.110"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..340)
                     /locus_tag="LP345_002644"
     CDS             complement(<1..340)
                     /locus_tag="LP345_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1761386.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSFEEKIP
                     HFSTFGKNYVR"
     gene            551..1540
                     /locus_tag="LP345_002645"
     CDS             551..1540
                     /locus_tag="LP345_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1761387.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1522..1983
                     /locus_tag="LP345_002646"
     CDS             1522..1983
                     /locus_tag="LP345_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL1761388.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            2033..2497
                     /locus_tag="LP345_002647"
     CDS             2033..2497
                     /locus_tag="LP345_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1761389.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2511..3260
                     /locus_tag="LP345_002648"
     CDS             2511..3260
                     /locus_tag="LP345_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1761390.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            3260..4090
                     /locus_tag="LP345_002649"
     CDS             3260..4090
                     /locus_tag="LP345_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1761391.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            4090..4737
                     /locus_tag="LP345_002650"
     CDS             4090..4737
                     /locus_tag="LP345_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1761392.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4835..5611)
                     /locus_tag="LP345_002651"
     CDS             complement(4835..5611)
                     /locus_tag="LP345_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1761393.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5693..5836
                     /locus_tag="LP345_002652"
                     /pseudo
     CDS             5693..5836
                     /locus_tag="LP345_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         2014 a          822 c         1058 g         2005 t
ORIGIN      
        1 ggcgaacata attctttcca aaagttgaga aatgggggat tttctcctcg aaggagtagc
       61 ctaaaaacca gcggtaagcg acattggtat cgacttcctt aatggtttgt cgcatggaac
      121 ggataccgaa taaatactga ataaacacca atttgatcag aatcactgga tcgatacttg
      181 ggcgacctaa atcggagtaa gtggcttcga cgattggata aataaattca aaatcaagcg
      241 cggcatcaat ctttcgaacg agatgatctt gaggaactag atcatcaatc gtaagcatcg
      301 caaattgatt tctaccattc gtattgtttt tagacatcat agctatcact ccttgcattc
      361 gttttcataa atctattata aaagaaaaga ctgtagacat catccataaa atggactttg
      421 tctacagtct ggcattttat tatataaaat tgttataaaa aatttttttt gaaaaatagt
      481 attgcaaaat aaagcaattt catagataat aggtatcgta aagttatata actttataat
      541 acctattaga gtgagggata aagaaatgag acaactacac aaagaacaga ttgaaacagc
      601 aatggcagcg ttaaaggaaa agacaattga tcatgtatat tttacagcat gtgggggttc
      661 acaagccgtt ttaatggctg gtcaatatct atttgataaa gaattaactg taccttgtca
      721 tgtttatact gctaacgaat ttaactatgc tataccaaaa ggattatctg aaaattcttt
      781 agttatcact tgttcccatt ctggcacaac accagaaact gtagaagcaa caaaaaaagc
      841 aagagaattt ggagcaatga ctatttgttt atctaatgaa gaaggatctc ctctatggga
      901 agcagctgaa tatcctgttc actatgattg gggtaaagat gttgatgcta gtgatttaaa
      961 taaaggaatt ctttatggtt tattatttaa tattttactt gttttagatg gctctaaaaa
     1021 atgggaaact tgcttgaatg aatttgataa gttaaatgat cttgttattg ctgaaaagag
     1081 caaatttgaa ataactgcta aagaatgggg taaaaaccaa aaacgagata aaattattta
     1141 cacaattggt agcggtatta attacggaga aatttactcc acagcagctt gctggttcat
     1201 ggaaatgcaa tggattaatt ctaatgctat tcattctggg gaatttttcc atggtccttt
     1261 tgaaatcact gattatgatg taccattcat cttagtgaaa agtattggag atacaagatt
     1321 tttagatcaa cgggtagaag acttcactaa aaaattcagt aataaattaa tggttttaga
     1381 ccaagctgat tttgacttag aatctataga tagtgtagcg aaagaatata ttgcagctgt
     1441 acttagtggc gttgttattc gccaaatggt agaagcgatt gcttttgaaa gaggccattc
     1501 cttagatgtt agacgctata tgtggcaaat gaaatattaa ttaataggag gttgcaaaag
     1561 atggcaaatc aattatttca cattgtgatt acaacacatt ctaccctttg tgagggttat
     1621 ttaaaggcaa caaaattaat tttaatgaat gacgccacag gtattagtgc tgttccattt
     1681 aaagaaaata ctagtccaga tgattttgag gagagtatga aagaaataat tagtcagcat
     1741 catttgcaac ctctaattat tttaacggat ttaattggag gaacacctaa taatgtttct
     1801 attaaacagt tgaacaacaa tagaattcaa attattgctg ggattaattt acctctttta
     1861 ctggagttat taatggccca gtcagctggt aaatctatag aagaaataga ttttaaggaa
     1921 ttactgaata actctcaaaa aagtatggtt catattaatt cgcttttaaa agatgtcagt
     1981 taaggtggca atttctattc tataaatttt aaaaattgaa ggaggaaata gaatgattaa
     2041 attagtgcgt gtagaccaca gattacttca tggacaagta atattttctt ggactaaaca
     2101 gtatgatatt aaccatatta ttgtggctga taacaaagtt ccaggagatc caatgtctgt
     2161 gatggctttg acaattgcta aacctgctga ttgcaaatta gacattgtta aaattagtga
     2221 tgttaaaggg attatggaaa catccccaaa tgataattac atgattttaa ttaaaggacc
     2281 taaggaagct tttgaattag ttcaaaattt accagaaatt aaagaaatta attttggcgg
     2341 tgtgtctaag aaaagcgagt ccaaacaata tggaaaggca gtctttttaa ctcctgaaga
     2401 attagaagcc acaaaaaaaa ttcttgatca agaagtgaaa atatttgtgc aacaagtccc
     2461 atcttcaagt attgaaaatg tagattttag taagtaaggg gggaaaataa atgttattaa
     2521 aagccatttt attaggttta gttggtgtgg tagctgttat tgactccagg ttaattggtc
     2581 gacaaaatat tggtagacca ctaattttga gtacacttgc cggacttgtg ctaggtgact
     2641 tgcatacagg gattgttctt ggggcatctt tagaattaat ttctatggga ttcgtctcaa
     2701 ttggggcggc tggacctcct aatatgcaac ttggtagtat tattgccact gcttttgcaa
     2761 ttttaactaa tagtagtaca gaaacagcct taacaatagc tatcccagtg gctgtagctg
     2821 gtgaatttat gagtattatc atgcgtatga taattgctca atttggacat gctgcagata
     2881 aagccattga aaataataaa tttagaaaag ctcaaattat tcatatttat tggtcattta
     2941 tttttaatgc ttttgtttac tttattccaa tctttttaac agtatatttt ggtgctgacg
     3001 ttgtggcaga tttagtagat aaaattccag aaatgattac agacgccttg actgtctctg
     3061 gaaatatgct ttccgcatta gggtttgcaa tgctattaag cacaatgttg agtaaaaaat
     3121 tatatcctta ctttattttt ggattcttta ttgttgccta ttcaggtctt tcactaattg
     3181 gcgtgacaat ttttgcagct ctgattgcct ttgtaatgga tcaagttaaa tatggaaaaa
     3241 gagaagaggc gcatggttaa tggaaaatag tacagaaaaa aaacgtttaa tcacaaaaaa
     3301 agatcttcat aagatgtgtc ttcgttcatg gacaatcatg tgttcgtgga attatgaaag
     3361 acaaatgcat atgggattta tgtatgggat ggcgccaatt ttaaataaag tttataaaaa
     3421 tgatgaagag aaaaaaagag aagcttatac tcgtcatatg gcatttttta actgtacgcc
     3481 tcaaatgact ccatttatta tgggactttg tgcttctatg gaagaacaaa atgctcaagc
     3541 agaagaagga aactttaata ctgaatctat ctccatgatt aaaaccagtt taatgggtcc
     3601 ttttgctgga attggtgatt catttttcca aggtacttta agaattatta catttgggat
     3661 tggattgtct tttgctaagc aaggtagtat tttaggaccg attttagctg ttggcctttt
     3721 tgctatacct tctattttag ctgtttttta cggcggtaaa ttaggatatg agtctggcaa
     3781 taaatacctt actaaattgt atcaagaagg tcttatggat cgagtaatgc aatttgcttc
     3841 tatcattggt ttggctgtag taggtggaat ggtggctagc atggtgccaa ttgtcacccc
     3901 tttaaaattc actacagggg gaacagaact tgttttacaa gacttacttg attccattat
     3961 tcctggatta ttaccacttg tatgtacttt gggaatatat aaattgatta agaaaaatgt
     4021 tagtacaaat atgctcttat taggttgtat tttggcaggg tttgttttaa gtataatagg
     4081 tatcttataa tgattaaggc tctaattttt gatatggacg gagttttaat tgatagcgag
     4141 attatgtatc aaaagtgggt atttaatttt ttaaaacaag aaaatttaag ctatcctttg
     4201 tattcttatc aaaaaaagat tggaactaca gcaagtattt ttgatgatat agaaaagtac
     4261 aatgagggat gtaacagttt agaattgaag ggaaaattta ctaaatattg gaaatcgcaa
     4321 aagattgatt acttggatat ttttcctaat atactaattg aacagcttga atggttaaaa
     4381 aagaaaaaaa taaaaatggc aattgcttct tccagtccaa tggatactat aaatgaagtt
     4441 gttaccactt gtaaaataga gtcatatttt gattgtttaa ttagcggaag agatttgcca
     4501 gaaagtaaac ctaatcctac tatattcctt aaagcttcag aacagctcag aattccagtt
     4561 gaagaatgtc tggtgataga agattcttat aatggtataa aagctggtaa aagagcaaat
     4621 atgaaggttc ttgcaattaa agataaacgt ttttctcaag atgtaagtct agcagatgat
     4681 gttatttacg atattaaata tctgcgacaa gaagtacagg tgaaatttgg aatataaata
     4741 agttttttga tgtatttaga gaatattagt aaaaataaaa atcatgccca aatctaatca
     4801 aaattgattg ctttgggtat gatttctttt aatatcaatc tattacttta ggatctgaat
     4861 catttttatg caccgtatct aaagtgatat tttctgtgac ttcaataaca taactaattc
     4921 tatcacaacg aactgtggat tgagaataat gaaatggttg attattttta tctttgccaa
     4981 ccttttctaa aataaatagc ggatctccta ctatacattg caataagtcg gaaagctcag
     5041 gtgttgcaga taaaccgttt atttccataa tagagctcgt agctttgaca tcatagtcat
     5101 cttctagaag tttatataat gaagtatatt ggctaccttt ttcaaataaa gttggaaatt
     5161 tttcttctga tgcgaaaaaa ttatcaattc ccatcggggc accgtcttcc cacattaaac
     5221 gtttaatatt gtaaactcta tcagttacat tgatttgtaa tttattagct aaaaactcat
     5281 cagcctttat aattttagaa tgtaaaacag tatatctaat tttatgtcct cgggtagaaa
     5341 gagaatcgct aaatccatga actccagcta attttaaact ttcttttttt tgagttacaa
     5401 aggtcccttt cccccttaat cgttcaactg ttccactttc tgttaaaagt ttaaaagctt
     5461 ttcgaatggt aatcttactt actccataaa ttttacataa ttcttcttct gtaggtaatt
     5521 gctctcctgg aagatatttt ttttcacgaa tatcgttacg tatagaagct tctacttgta
     5581 gatataatgg tctattatct tgaaaattca tagtacactc cctaaaaagt tatacttcat
     5641 tatatcacaa tttattaaaa taaaagatta agatataaat ataaatgaac tagtctttga
     5701 ctaaccaatg cccgcttttg aaagaaaaca aattcattct gttttaagta aaaatcctta
     5761 tgttaccact cattctgaag gggatgagcc ttatcgctac ttggttgtgg aaccaagcga
     5821 taagacaatt ttataaattc aatattaatt aaaataaaaa caaacaaagt agattatttt
     5881 actttgtttg tttttttat
//
LOCUS       DAFEIE010000105         5391 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFEIE010000105
VERSION     DAFEIE010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.111"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(203..565)
                     /locus_tag="LP345_002653"
     CDS             complement(203..565)
                     /locus_tag="LP345_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761394.1"
                     /translation="MKKTMLKVFVGLFLLTGIGGIFSKTVDAGSYYYDKSSGNYVINV
                     TNSETGKNLNSIAGKTPGSVTNKMRNAAIKRYGSIQNNRRYYFSYKNIVTPYGGKKGG
                     VSFQWTGRVINMNCTGRS"
     gene            661..1032
                     /locus_tag="LP345_002654"
     CDS             661..1032
                     /locus_tag="LP345_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1761395.1"
                     /translation="MNKNKYYPIYEDLKYKIQHGEYKENEKIPSENQLCNLYSSSRAT
                     IRKAIELLAIFGFVDRSQGKQTIVSSKKNWNKRFLTEEEYKKLVLFNLKSTELNEIIA
                     LSEKYSVLKKLVDFWNNNNLI"
     gene            2138..3070
                     /locus_tag="LP345_002655"
     CDS             2138..3070
                     /locus_tag="LP345_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL1761396.1"
                     /translation="MANEIVKYEPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFSQLKDLSAYKQTAGEVFIKDLTRTYDHLMDLRFGKKSNGGLTIERFTMFTDFEIH
                     GEVDNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKHEDLRIKLFNIEHNGELTQEEKWRAKDRILNLPLGTHEAD
                     FKKQQQTEKEGTQKQALSNELKQDLIGNLQNLFD"
     gene            3086..3610
                     /locus_tag="LP345_002656"
     CDS             3086..3610
                     /locus_tag="LP345_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL1761397.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSKENRKLWFSKVGNKFVIND
                     IGQKAIKSMFYSENENLNRKLVSGKTKTENLKNANQVSELELVSLLNKQLDQKDKQLQ
                     EKDTQLKQMQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKTEKKWWQFWQ"
     gene            3986..4267
                     /locus_tag="LP345_002657"
     CDS             3986..4267
                     /locus_tag="LP345_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761398.1"
                     /translation="MDILVRKIDSKIISEIDRRCQELTTKTSKKWSRNTYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNEYVRTNNQLIETLIGGL"
     gene            4269..4685
                     /locus_tag="LP345_002658"
     CDS             4269..4685
                     /locus_tag="LP345_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761399.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISILSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNHQKETNQTFTAGNFDPTNFLKR"
BASE COUNT         2017 a          870 c          868 g         1636 t
ORIGIN      
        1 aaaaaaaact atgttggtac taggttctat ttctctagga gtattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaataattc caaaggggaa cttaaattaa atccaaatta
      121 ctacaatagt cctaatgaac ctatgtttat ttcagaaaag caaaacgacg gtcaggacaa
      181 ataatcctgc cgtcgttttg ctctaacttc taccagtaca attcatgttg attactcttc
      241 cagtccattg gaaacttacg ccaccctttt tacctccata tggcgtaact atgtttttat
      301 aagaaaaata ataacgtcta ttattttgaa ttgaaccgta tcttttaata gcagcatttc
      361 tcattttatt agtcactgat cctggagtct ttccagcaat agaatttaaa ttttttccag
      421 tttcagaatt tgtaacgtta ataacataat tcccactaga tttatcataa taataagaac
      481 cagcatcaac tgtttttgag aaaataccac ctataccagt taatagaaat agaccaacaa
      541 atacttttaa catagttttt ttcatataaa aacctccttt agtttaagaa tatactaata
      601 attataaaga aaacgtttta tattatcaat gttaaaataa taaaaaggag agcttgatct
      661 atgaacaaaa ataaatatta tcctatttat gaagatttaa aatataaaat tcagcatgga
      721 gaatataaag aaaatgaaaa aattcctagt gaaaatcaat tatgtaatct ctactctagt
      781 agtagagcaa ctatcagaaa agctatagaa ctattagcta tattcggatt tgtggataga
      841 tctcagggaa agcaaaccat tgtttcatct aaaaaaaact ggaataaaag atttttaacc
      901 gaagaagaat ataaaaaatt agttctattc aatttaaaaa gtactgaatt aaacgagatc
      961 attgctttat ctgaaaaata ttctgtatta aaaaaacttg ttgatttttg gaataacaat
     1021 aatttaattt aactagcaaa ttttctaaaa agataaaaaa agaagtgggc aatatgggaa
     1081 attaaaccac tacttttttg ttttgttgct ccagcaacgc ttagtcctaa attatccgaa
     1141 agataaaata acaaataaaa tgttcattta ccatataaat ggtcgctaaa ataagcccac
     1201 aaaaaagagc cattaaccct ttgattataa aggattaatg gttcttttat tcttcgaata
     1261 ttttctattt atttgataaa atcacgattt ttttgaattg tgctaccaaa ataaatgcct
     1321 gtatatcaat cattgctacc aaatatttct ctgttattta gcattacgct cccctattag
     1381 agtagggggc acagtatttt ctacctgttt tgggggtttg tcccacatag cattggtgtt
     1441 caagtgctcc gtttttctgt caaaaaggtt cttcctggtt tcatatgttt atgggcctta
     1501 atttgcattt taagttgttt tggtgtctga atcatataag tataccaaag gatgggcaaa
     1561 acagcttaaa tcgaatttta gaaagggttt atgacgttcc agggttgtta gggcttgccc
     1621 tgaccgccta taaggcgctt taagagcaag ataagggttt ttatttaact tgtcgtagaa
     1681 agccttaaac aagcatttag ggaataataa aggccttttt aggaacgggt tgaagcaaag
     1741 gagcctttag tcgactgcgc agtacaatgt gagagcgtag cgatcacacc tttttagcga
     1801 ccgtagggag ccagtttccc agtttaggaa aatgcgcgaa tctgtttgag gagaaaagga
     1861 gtaatttttt aggcgggaaa ttttgcactc cctcttttat aatctctttt taaatctctt
     1921 tttaaacctc tttaccgtcg tctgttccct tactctccca aggggtgtag cttttttagg
     1981 gcatgaaatt atctgtttat aggcatgaaa ttatctgttt ataggcatga aattatctgt
     2041 ttataggcat gaaattatct gttttaggta ttgttttaag acataatatg tcttaaaatt
     2101 atgtcaataa aattagttag actggagtat caaataaatg gcaaatgaaa ttgtaaaata
     2161 tgaaccagaa ttaaatacca ttcctttaag aaaatttacc ccaatagaaa tgaacttgtt
     2221 tttttctatt gtctctagaa tgcgtgataa aggtaatcaa aaaatacgct tttatttcag
     2281 tcagcttaaa gatttaagtg cttataagca aactgctggg gaagtcttta taaaagattt
     2341 aacaagaaca tacgatcatt taatggattt acgttttgga aaaaaaagca atggtggatt
     2401 aaccatagaa cgatttacaa tgtttactga ttttgaaatt catggagaag tcgataaccc
     2461 ttatgtagat ataaaagttc acgaaaaagc tttgccttta cttaacaatt tagaaagttg
     2521 ggtacgtttc tctttaacag aatttcgaga tttaaatagc agttatgcta aaacaatgtt
     2581 tagattgcta aaacaatacc gaactcaagg atgggctgaa ttttccaagg aagatttttt
     2641 agagctatta gatattccta aaagctatag acaaacaaac ataaatcagt ttgtactcaa
     2701 acccataaaa gaagaactaa ctccactgtt taaaggatta acgattcgta aaaaatatgg
     2761 taaaggacga ggaaagcctg ttattggtta tcggtttact tggaaagctg aaattaatca
     2821 tgctgacgat ttctcaaaag gaaaacatga agatttacgt ataaaattat tcaatattga
     2881 gcacaatgga gaattaactc aagaagaaaa atggcgcgct aaagatcgaa tattaaatct
     2941 tcccttaggc actcatgaag cagattttaa aaagcagcaa caaactgaaa aagaaggaac
     3001 acaaaaacaa gcactctcaa acgaactcaa acaagattta ataggaaatt tacaaaactt
     3061 attcgattaa atataaggag tatttatggc agataaaact atcaaagaac ttgctgaaga
     3121 attaggggtt agtaaaacag caatcaataa aaaagtttct aaagaaaatc gaaaactttg
     3181 gttttcaaaa gtcggaaaca agtttgtgat taacgatatc ggtcagaaag ctattaaatc
     3241 aatgttttat tccgaaaacg aaaacttaaa tcgaaaacta gttagcggaa aaacaaaaac
     3301 cgaaaacttg aaaaacgcta accaagtttc cgaattagaa cttgtatctt tattgaataa
     3361 gcaattagac cagaaagaca aacagttaca agaaaaagat actcaactaa aacaaatgca
     3421 aaaattactc gatcagcaac aacaactcac cctgcaagcc aaccaacaaa tcgagaaact
     3481 gcaggaacaa ctacagttga cttatacgga agaatcttcg gaaaataaat caactactct
     3541 ttctgaagaa acagaatcga tagaaaaaca atcaaagacg gagaaaaaat ggtggcaatt
     3601 ctggcaataa aaccagcaat ttttattaat aaaaattgct ggttttattc ttctttttgc
     3661 ttttgcgagc agagcaacat gggcccatgt tgcgatattt tggtagcgcc ccaatccccg
     3721 ctttttcgtt gaatcttact cagactgcac tcgttttata gctgattttt ctgaattttg
     3781 aaagagcata aggaaacgtg gtatcacttt cttacgaaag gtgatagata ggctgtgcct
     3841 atcacatttc taagaaaaaa atttgctatc acttttttgc cattatggat agtgtatgta
     3901 tagtattttg gtaaaaaaca gctatacaaa tactatattt gtatgatata catagattat
     3961 acgcacatgc gaaaggaaaa ttgctatgga tattttagtt cggaagattg attcaaaaat
     4021 tatttcagaa atagatagac gttgccaaga acttacaacc aaaacgagca aaaaatggag
     4081 ccgtaatacg tacctaaaag ttctaatcga aaatgatttt gaccaggcac ttaggcatta
     4141 caaaaaagat caattcgatt tattactcga aaaatttatc gatatacaag caaaaaatac
     4201 ggaaacactg aatgaatatg ttcgtacaaa caaccaactc attgaaacac ttatcggagg
     4261 actataacat gagaaaaact tctgttcaaa aacacgttac cctttatccc agtcacgtgg
     4321 acgttttaga ttccattatt gaaagaaatc cagatatcaa caattactcg gaagccattc
     4381 gttttttatg tatgagttat gaacctgata ccaacacaac cactactagc aaccaagcca
     4441 aactaaatgc tatgggaaaa gaaatttcta tcctgtccga aatcattgca gaatttgctg
     4501 atttatatct aaaagatact ggtgttctta ttggtaccaa ttctaaggtg tatcaagaag
     4561 tgaaagaaaa aattgaaaat caactcaatc cttcccgacg aaatcaaccc aaaaatcatc
     4621 aaaaagaaac caatcaaaca ttcactgctg gaaattttga cccaaccaac tttctaaaaa
     4681 gataaaaaca gaacctgaaa aataaaaaaa ttcctcgatt tctttttagg gggggcggtc
     4741 ttccagcaag atttgcaagt tgggaccaac ttgcggaaaa aaagaaaaat tcgcttgcgc
     4801 gaatccttct ttttgcattt tggggcgctg ccccaatccc caagtatcgg ttatttaata
     4861 gcgtggcaac tcaaagaaca gaacatactc tgaaacaaaa aaagactgct ctaacgagca
     4921 gccagttaaa aaataatgag tgtttattct tgaaaaagca acgcgcttat gaagcgctac
     4981 caaaaattta tcatatttta ttaaaaataa caacccagta aaaaatgact ggtaaaaatt
     5041 cacaaagaaa cggaaagaag caaccgcaga aaatcaagct taaaaagagc tttttaccta
     5101 gaccaatgaa aaatcacaaa gtccgcccct gtacctgttg gtagctgggc tacttggcat
     5161 actgtacatt atgttaactt gaatttaaaa taacatgtat tattgtatta taaagcggac
     5221 tctattgaaa tctataattt tcacttttaa atattacaaa aaatcatata atttgagtta
     5281 ttattgttta gaagtgattt ttacaattta aacatttgac aaactataga acagcactta
     5341 aaatgtgtat acaagtgaca gcgctttaaa aaaggaggtg cagcctatgt t
//
LOCUS       DAFEIE010000106         5255 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFEIE010000106
VERSION     DAFEIE010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.112"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(46..366)
                     /locus_tag="LP345_002659"
     CDS             complement(46..366)
                     /locus_tag="LP345_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL1761400.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(514..2748)
                     /locus_tag="LP345_002660"
     CDS             complement(514..2748)
                     /locus_tag="LP345_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1761401.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQKAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            3227..3493
                     /locus_tag="LP345_002661"
     CDS             3227..3493
                     /locus_tag="LP345_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBL1761402.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            3493..5220
                     /gene="ptsP"
                     /locus_tag="LP345_002662"
     CDS             3493..5220
                     /gene="ptsP"
                     /locus_tag="LP345_002662"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBL1761403.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
BASE COUNT         1580 a          983 c         1057 g         1635 t
ORIGIN      
        1 tttacttttg tcccacgctc tttaattatt atgttcaaaa tttgtttaca cggctaatgt
       61 agcgcctaat tcatgttttg gaatcgagat ttcaacaagg cctgccaatt cgattacttt
      121 gatttcatcc tcgtggtaaa cggcgtcttt gattttatct aagaaataat ttttagcatc
      181 ttcgatttct ttcggctgga ttttacgttt gtcattgatc agcagaattt cattatgttc
      241 aggggcttca gtgtagacaa tagtggtatt tccggctgtg tagaccttga ctagatgggc
      301 atcagtgttt tcaagctggt ttaatacaag acgggaatgg ctgtttgtta catttaccaa
      361 tttcatggcg ctcacctctt ttatgtattt ttaattgctt gtttctctta ttataatttc
      421 ttttttataa aatgaacagt attttgactt ttctgaaaaa agaatgagac ggcatttctc
      481 aaagaaatac cgtctcacgc tataaaactg gatttattca gccgtttctt cggctgattc
      541 tttagccaaa cgttctggtt tagaagtaac gatgattttt ccatctttat ccagttttgc
      601 tttcaactca tggatagaag ggtgatcaag ataaaattca gcgataccat cttcgatttg
      661 ttcttggatc gtgcgtcgaa gaggacgagc acccatagat ggatcatagc ctaagtcaac
      721 taatttttct ttgacattcg taggaacttc gatgtgaagt tgctgtgctg ccagcatttg
      781 gttgacatcg tctagcatta gtgtgacgat tgtcatcaag ttttcttttg ataatgcact
      841 gaattcgatg atcccgtcaa aacggttcag aaattctggt gtaaagtagt tgtttaattg
      901 gttcaataca gaacgagtaa caccttcgcg tgccgcacca aaaccaacgt ttgcttctac
      961 tttaccagtt ccggcattac ttgtcataat gatgatcgta tctttaaagc tgaccgttct
     1021 tccttgtgca tctgtcaatc gaccatcatc taagatttgc aagaacatat gcaaaacatc
     1081 tggatgagct ttttctactt catctaacaa gacaagactg taaggatttc tccgtacttt
     1141 ttctgttaat tgaccagctt cttcgtatcc gacataacct ggaggagaac caatcaattt
     1201 agagacacta tgtttttcca tatattcaga catatcgaaa cgaatcattg aatcttgtga
     1261 accgaatagt tcgtaggcaa gttgtttcgc aagctctgtt ttacctacac cagttggtcc
     1321 aacaaataag aaggagccga ttggacgatt ctgtttgttt aatccaacac ggtttcggcg
     1381 aatcgctttc gctactcgat ctacagcgtt atcttgtccg atgacatgag ctttcaagtc
     1441 atctgctaag tttttcagtt gtgtctgttc tttttctttt aattcaccca ctggaatacc
     1501 tgtccgttgt tcaacgattt tttccatatc tttttcggta atcacaggtg tttcctcttc
     1561 agtgagctga cgttctttca ttttttgaag tttattgatc tgatcgcgat aataagctgc
     1621 tttttcgaaa tcttcttctc gagaagctaa aactttttgt tcttctgctt tttgcagttt
     1681 tttctcgatt gttttaggat caacgatttg gatcgtcaag tttttcttag aacctgtttc
     1741 atctagcaaa tcgatggctt tatccggcaa gaagcgatct tggacgtaac gattggataa
     1801 agttgcggct gcttcgatgg cctcatcagt atattttaca tgatgatagt cttcataacg
     1861 tttttgcaaa cctttcaaaa tactgatcgt ttcttcgaca gttggttcat ctacccgtac
     1921 aggttgcata cgacgttcta aagcagcgtc tttttcgatg atgcggtact catttaaggt
     1981 agtagcacca accatttgca attctcctcg agctaaagct ggttttaaaa tattaccagc
     2041 atccatattt ccatcaccag cagaaccagc accgactatt tcgtgaactt catctatgaa
     2101 taggatcaca ttttctgctt gacggatctc ttcaatcaat ttttgcatac gttcttcaaa
     2161 ttgtcctcgt ataccagtac cttggactaa agatacgaca tctaaacgaa tgacttcttt
     2221 gtccattaat ttttgcggta catcaccatc tacgattttt tgtgctaaac cttcaacaac
     2281 tgctgtttta ccaacacctg gttctccaat caagacagga ttgttcttgg ttcggcgatt
     2341 taaaatttca atgactcgtt tgatttcgtc atcgcgtccg atcacaggat cgatatcacc
     2401 ttgtcgtgct tgttctgtga tattgattcc gtattctccc aataaacctt ctgtattgcc
     2461 ttgaggtggc tgaccaccat tgaagttgtt gtttccgcca aattgtgttg gtggtgtttg
     2521 ctcataattt ccttgctgtt gcatttggcg agacatggaa cggaaaagat cgtccaaact
     2581 gccaaatcca aatggatcat tttgggccat attagtcaga cctccatttt gttgattttt
     2641 gattttttga taacagctct gacagtaatc gagttgtgtc cgctgaccat tgacagtggc
     2701 atacaagtga atcgttgcct cattcttgcc gcagttttga caaagcatga atcattcacg
     2761 tcctttcaca aaaatgggta catccatatt ttacatctcg tttttcatga ggtaaaagaa
     2821 taacccctag ttttttaaga gatttatgag gtagaaaagg tgaaatctct attgaccatt
     2881 cctgaccttt gactcttatt atactaaaaa taaaaaggga agcaagtaat tcgtttcata
     2941 tgaaaacaaa gagggtcaaa ggaaagaatg ataaacgtca ggagaagaga aagcgacaag
     3001 aaaaaggaaa taaacacgtt tgttataaaa tgtgaagaaa aggatgaaaa agaatccgga
     3061 ataatttgaa tacttttatc tgaaattgaa tgaaaactgt tgtatctaac gaaaaaaaat
     3121 gttaatcttt acagatgaaa gggtggcatt tgttaggatt ctctgaatta ctaaaaaaga
     3181 aaaccctcac ataaaaacaa cactcactta aaggagaccg attaatatgg aaaagaaaga
     3241 atttcacgta gtagcagaaa ctgggatcca cgctcgtcca gctacactat tagtacaaac
     3301 agcaagcaaa tttaactctg atgtaaactt agagtataaa ggtaaatcag taaacttgaa
     3361 atcaatcatg ggcgttatgt ctttaggtgt aggtcaaggt tctgatgtta ctattactgc
     3421 agaaggtgct gacgaagctg atgcaatggc agcaatcgtt gaaacaatga agaaagaagg
     3481 cttatctgaa taatggttga aatgctaaaa gggattgccg ctagtgacgg tgtagccgtt
     3541 gcaaaagctt acctgctagt tcaaccggat ttaacattca gtaaggcaac agtagaagat
     3601 actgcggctg aagaagctcg tttggatgct gcattagcta aatctactga agaattgcag
     3661 caaattcgtg aaaaagcagc gcaaagctta ggtgaagcag aagcgcaagt atttgatgcc
     3721 catttgatgg ttctttcaga tccagaaatg gtaggtcaaa tcaagcaaaa tattaaagac
     3781 aacagcgtaa atgctgaatc agcgctaaaa gaagtaacgg atatgtatat cggtatgttc
     3841 gaagcaatgg aagataatgc ttatatgcaa gagcgtgctg cagatattcg tgacgttgct
     3901 aaacgtattt tagcgcactt attaggcgtt actttaccaa atccatcaat gatcaacgaa
     3961 gaagtggtcg ttgttgcaca tgacttgact ccaagtgata cagcacaatt agatcgcaat
     4021 tttgtaaaag cgtttgtaac agacattggt ggacgtactt cacattctgc tatcatggca
     4081 cgttctttag aaattccagc aatcgttggg acaaaagaaa ttactgctaa agtcaaagaa
     4141 ggcgatattt tggctgtcaa cgggatcgaa ggcgatgtaa tcatcgatcc tacagatgaa
     4201 caaaaagctg aatttgaaaa agcaggtgca gattacgcag cacaaaaagc agaatgggaa
     4261 aaattaaaaa atgcagaaac tgtcacagct gacggcaagc attttgaatt agctgcaaac
     4321 atcggaacac caaaagatct agttggtgtc cataataatg gtggagaagc agttggtctg
     4381 taccgtactg aattcctgta tatggattct ccagacttcc caacagaaga tgaccaatat
     4441 gaagcttaca aagctgtatt agaaggtatg gaaggaaaac ctgtagttgt tcgtacaatg
     4501 gacatcggtg gagataaaga actaccatat ctgcaattac ctcatgaaat gaatccattc
     4561 ttaggatatc gtgcattgcg tatcagttta tctgaacaag gcgacgaaat gttccgtaca
     4621 caaatgcgtg cattgcttcg tgcatctgtt catggtaatt tacgtatcat gttccctatg
     4681 gtagctacac tcaaagaatt ccgcgcagca aaagcgatct ttgaagaaga aaaacaaaaa
     4741 ttgataagtg aaggcaagga agtatctgat acgatccaag tcggcatcat gatcgagatt
     4801 ccagcagcag cagtcttagc agacaagttt gcaaaagaag tagatttctt ctctgtaggt
     4861 acgaacgatt tgattcaata cacaatggca gcagaccgta tgaacgaacg cgtttcttac
     4921 ttgtaccaac catataaccc atcaatttta cgtttgatca aaaatgtaat tgatgcagca
     4981 cacgctgaag gaaaatgggc aggtatgtgt ggagaaatgg ctggagatca aacagctgtt
     5041 ccattgctag taggtatggg tctagatgag ttctcaatga gtgcgacatc tattcttaaa
     5101 acgcgtagtt taatgaaacg cttggacaca gcgaaaatgg ctgaacttgc tgatcgtgca
     5161 ttgaaagaat gcgatacgat ggaagaagtc gttgaacttg ttcatgaata tgtaaaataa
     5221 acaacgtatc aaaagctggt gtggcttgta aaaga
//
LOCUS       DAFEIE010000107         4982 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFEIE010000107
VERSION     DAFEIE010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4982
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.113"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..156
                     /locus_tag="LP345_002663"
     CDS             <1..156
                     /locus_tag="LP345_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBL1761404.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
     gene            175..1452
                     /locus_tag="LP345_002664"
     CDS             175..1452
                     /locus_tag="LP345_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1761405.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1462..2118
                     /locus_tag="LP345_002665"
     CDS             1462..2118
                     /locus_tag="LP345_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1761406.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2118..3494
                     /locus_tag="LP345_002666"
     CDS             2118..3494
                     /locus_tag="LP345_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1761407.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(3780..>4982)
                     /locus_tag="LP345_002667"
     CDS             complement(3780..>4982)
                     /locus_tag="LP345_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HBL1761408.1"
                     /translation="DNLYLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRI
                     EAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGEREKQFAYSAHTSCDDNGFILST
                     IITPGNIHDSQVAFQLVKQSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSR
                     PKGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTRERYREYKSNPKECVNCPLLNQ
                     CTKSKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMRW
                     TKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTSL
                     EQLLSTVCDVGDISFSIRNQLRFKRSLPVSGNINVYFTKARFKRLIAITVSSIVMFLW
                     LFRMGVIP"
BASE COUNT         1864 a          636 c          883 g         1599 t
ORIGIN      
        1 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
       61 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      121 ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag gaaagtgata
      181 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat ttttatcata
      241 ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc aagcaatgaa
      301 atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa aaaagatggt
      361 aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat tgaagaaaaa
      421 ataattcaat atgatggatt agcaaaatta aaagatgcta aagtagttag cggagaacaa
      481 agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact cgaagctaca
      541 aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa agaaggtaaa
      601 aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc taaacaaaac
      661 aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa aagtggaaaa
      721 ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca ggaaacatat
      781 acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc aacaagccaa
      841 gagatattaa ataattcaga aaataatgaa attgcaaata aaattttaat gtattctggt
      901 agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat tgatgagtca
      961 aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc agtgagtgga
     1021 ataaaatata taataaaagt aatgacttat tctattatgt taggtgggat ggttgttctt
     1081 tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat attcttatct
     1141 attggaacat ctaagataca aattataatg caatttatat tcgagttaat attcatatcg
     1201 ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt aattgtagat
     1261 ggattcatta actcagagga ttcaatgatt tccggtggaa gtttaataaa taatagtagt
     1321 tttatgtcaa atataacaac acttggacaa agttatttaa tattaataag tattattgtt
     1381 ttatcagttg tatttgcttc ttcattaatg ttaatcaaga agcctaaaga aatcttatca
     1441 aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc atatagttat
     1501 gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact tgggaagttt
     1561 tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt acttgctgga
     1621 cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca aaataaagga
     1681 tatagtaatc atagaaaaaa taatatatct ttagtatttc aaaactataa tttaatagat
     1741 tatttatcac caattgaaaa tattagatta gtaaataaat cagcagatga aagtatcttg
     1801 tttgaactag gtttagataa aaaacaaata aaaagaaatg ttatgaaatt atctggtgga
     1861 cagcaacaaa gagtagctat tgctagagca ttggtatcag atgctccaat aatactagct
     1921 gatgagccta ctggtaatct agacagtgtt actgctggag aaataattaa tatattaaag
     1981 acattagcta aagatagaaa taaatgtgta atagttgtaa cacatagtaa ggaagtagca
     2041 gattctgcgg atatcatttt agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg
     2101 aatttggagg ttgaataatg ataaaaaatg catttgctta tgtaactaga aaaagtttaa
     2161 aatcattaat tatcatatta gttattttat ctatgtcaac tttaagtctc attagtttat
     2221 ctattaaaga tgctacggac agagcttcaa aagaaacatt tgctaatata acaaatagtt
     2281 tttctatgga gataaataga caagtaaatc caggaacacc tagaggtggg ggaaatgtaa
     2341 aaggtgaaga tattaaaaag atatctcaaa cagatagtat agactcctat gtaaaaagaa
     2401 taaacagtgt tgcagattta gttgattatg atattattga aactcaagag actcttgcga
     2461 atcaatcacc tgaaagagca aagaatttta aaagaacagt tatgttaact ggggttaacg
     2521 actcaacaaa agaaacaaaa tttgtatcag aagcatataa attagtagaa ggaaagcatt
     2581 tagaaaatga agataaaaat aaaatcttaa tgcataaaga tttagctgaa aaaaataacc
     2641 ttaaagttgg agataagata aaaataaaat ctaatttatt tgatgctgat aatgagaaag
     2701 gtgcagatga aacagtagaa gtagaaatta aaggtctatt cgatgggcat aatagcggtg
     2761 tagtaagtgc agcacaagaa ctatacgaaa atacattaat cactgatatt catacagctg
     2821 ctaaagttta tggtaatacc gaagatacag ctgtatacca agatgcaaca ttctttgtaa
     2881 aaggtgataa gaatcttgat agtgtaataa aagatcttgg gaaattagat ataaattgga
     2941 gagaatataa tttgattaaa agttcatcaa attaccctgc attacaacaa tctatatcag
     3001 gtatttactc aatttcaaat aaattatttt ttggctcatt aatatttgca ggagttgtag
     3061 tttcattatt attattctta tggatgaatg ctagaaagaa agaaatagca gtattactat
     3121 cattaggtat atcaaaatta gaaatttttg gtcaattcct aattgagatg gtatttatat
     3181 caatccccgc attcgttggt tcctatttct tagctcaata tacagctgac aagcttggga
     3241 ataatatatt gaataaggtt actggtgata tagctaaaca aatagctaaa caatctgcat
     3301 ctagccaatt aggtggtggg gcagaagctg aaggatttaa caagacatta tcaagtttag
     3361 atatcaatgt attacctaaa ttcatgattt atgtagttat atttatgagt ttagtacttc
     3421 ttgtatcatt gattatttct tcattcaata tattaagaag gaatccaaaa gaattattaa
     3481 ttgacaataa ttaaaatttt cggtgctttt tagcaccaaa aatgagagtg taatataaac
     3541 cgtgtaagta accatcaatc ctaggcgggt ggttgcttca cggtttttat ttttctaaaa
     3601 taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat gctgagaagt
     3661 tagctgaatc cattttgaat acttatcaac ccgaatctgt agaggatatg caagatgttt
     3721 taaaagatgt gtttggtccc ttatttgaaa aaatgcttca aggagaattg aataaccatt
     3781 tagggtatga cgcccattct aaagagccaa agaaacatga caatcgacga aacggttatg
     3841 gcaataagac gcttaaaacg agctttggta aagtaaacat tgatgttccc agagaccggg
     3901 aggcttcttt tgaacctgag ttgattccta atagaaaacg agatgtctcc gacatcgcag
     3961 actgtagaca aaagctgttc caaactcgta actcgagctt ggaacagctt tttatctact
     4021 tcgtttcgaa tttttgaaca aaaaaataaa ggctccttgc ctttccatag ccaggtggct
     4081 aatttcttta aattcattgc agcaaacact agcatcgtat gcgtcgcgac tttttccaag
     4141 cctcgatact tggtccaacg catcccatgc ttttcttttg catccgcaaa tattcgttca
     4201 atcgtttgtt tccgtttttt gtaaattgat ttattcagat ctgttaggcg aagatgttcc
     4261 acttcatcca tcagatctcc ccaaacatgt ctcgtgatga ctcgttgatg atttttactt
     4321 ttggtacatt ggtttagcag aggacagttc acacattctt ttggattgga tttgtattct
     4381 cggtaccttt ctcgagtaac cgttgaaaaa gcgagcattt gatcttgcgg acaaatataa
     4441 caatcaaaat actcgtcata gagaaactca ttttttgata atagcccctt tttccctttg
     4501 ggccttgaat aaggcaaaca aggtcgaagg ttcaaatgag tcaaaaagtg aacaaactta
     4561 ggtgtcttat acccagcatc agcgacaaca caattgattt caggaaaaag tctcttcgat
     4621 tgtttgacga gctgaaaggc gacttgactg tcatgaatat ttccaggagt gatgattgtg
     4681 ctaagaataa atccattgtc gtcgcatgaa gtatgggcag aataagcaaa ttgtttttct
     4741 cgttcgcctt tgacgtagta gccgctttcc ggatcagctt tacttatttt tctttctttc
     4801 agcttcactt ccttttctaa gtccaaagta aaagggcgtt ttccagcctc tattcgttga
     4861 cgattgatct catcttctaa ttcatcctga taggctttcg cttcatcatg ggtcatttct
     4921 ttcgtaaact tatgtttatt ggcgttagct ttgatgtggg tagaatccag atacaaatta
     4981 tc
//
LOCUS       DAFEIE010000108         4907 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFEIE010000108
VERSION     DAFEIE010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.114"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            77..1024
                     /locus_tag="LP345_002668"
     CDS             77..1024
                     /locus_tag="LP345_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HBL1761409.1"
                     /translation="MHLEFSDYESLLVKICEDYYLEDINISEISKKYGITRYKALKYI
                     EDAREKQLVSISINSPYARNYELEEIFKNYFKTNIYILKSSEDLSQHDLLFSKFAADY
                     IQELIKKANVVALSWGDTVYKVIDQFKMGAREELIFTQFIGEIGKYNSLAGSTRLVQK
                     AAERYESSYLTLSIPLYVINETARELMALEPSLANTLATASHADMLISGIGTLSSIDS
                     VEPWNKHRKILFPSMTDTVGFLYGRPFNINGEFIKASEDKTFGLSLKEIFDIPKRIGI
                     CKSKFKAESCLGALNGNFFTDLFLDEKTAWKILSLIKKE"
     gene            complement(1317..1865)
                     /locus_tag="LP345_002669"
     CDS             complement(1317..1865)
                     /locus_tag="LP345_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761410.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1866..2723)
                     /locus_tag="LP345_002670"
     CDS             complement(1866..2723)
                     /locus_tag="LP345_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1761411.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(3009..3296)
                     /locus_tag="LP345_002671"
     CDS             complement(3009..3296)
                     /locus_tag="LP345_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1761412.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            complement(3286..3615)
                     /locus_tag="LP345_002672"
     CDS             complement(3286..3615)
                     /locus_tag="LP345_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1761413.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(3692..3964)
                     /locus_tag="LP345_002673"
     CDS             complement(3692..3964)
                     /locus_tag="LP345_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL1761414.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTYEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3964..4227)
                     /locus_tag="LP345_002674"
     CDS             complement(3964..4227)
                     /locus_tag="LP345_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1761415.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDLKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            complement(4333..4749)
                     /locus_tag="LP345_002675"
     CDS             complement(4333..4749)
                     /locus_tag="LP345_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761416.1"
                     /translation="MEFREGAFDFQTSQQNRKFIPEDFQNLQLENMRLEDLFRLADDD
                     KYRFEVLKIKKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNR
                     NSTDVVMITDIYVEDEVIIKYMKPVIKLVNKNKGNG"
     gene            complement(4755..>4907)
                     /locus_tag="LP345_002676"
     CDS             complement(4755..>4907)
                     /locus_tag="LP345_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL1761417.1"
                     /translation="NKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFSFSVSTEIKV
                     LMGITA"
BASE COUNT         1473 a          921 c          681 g         1832 t
ORIGIN      
        1 tttaaaaaaa gactaaattc aatttttttg gtataatgag aaaaaatatc tatttgaaaa
       61 agttaggagc tatactatgc atctggaatt ctctgactat gaatcactcc ttgtaaaaat
      121 ttgtgaagac tattatctcg aggatatcaa tattagtgaa atttctaaaa aatatgggat
      181 caccagatat aaagctttaa aatatattga agatgcacgt gaaaaacaat tagttagtat
      241 ttcaattaat tctccgtatg ctaggaatta tgagctagaa gaaatcttca aaaattactt
      301 taaaacgaat atctatatat taaaaagtag tgaagactta tcacaacacg atttattatt
      361 ttcaaaattt gctgccgatt acattcaaga attaattaag aaagccaatg tggttgcact
      421 atcttgggga gataccgttt acaaagtgat tgatcagttt aaaatgggtg ctcgtgaaga
      481 attaattttt actcaattca ttggcgaaat cggaaaatat aattccttag ctggctccac
      541 acgattagtt caaaaagctg ctgaacgtta tgagtcttct tatttgactc tcagtattcc
      601 tttatatgtc atcaatgaaa ctgcacgtga actaatggct ctagaacctt ctttagctaa
      661 taccttagca accgcttcgc atgcagatat gttaatttct ggaattggca ccttatcctc
      721 tattgattct gtcgaaccct ggaacaagca tcgtaaaatc ctatttccaa gcatgacgga
      781 tactgttgga tttctttacg gaagaccctt caatatcaat ggtgaattca tcaaagcatc
      841 tgaggataag acttttggtc tttctttaaa agaaattttc gatattccaa aacgaattgg
      901 tatttgtaaa agtaagttca aagcggagag ttgtttaggc gccttgaatg gtaatttttt
      961 tacagattta tttttggatg aaaaaactgc ttggaaaata ctttctttga taaaaaaaga
     1021 gtgagtcatg taaaatcctc caaaaaattt agatttttgg tactactttt ttggagggca
     1081 gtacaatgat tcactctttt tattggatat caaaatccct ttttttgaga agcttgtctt
     1141 gatatttttt gaacttttcc aagccatact ccattacttt tcaagattta atttctttgt
     1201 attcactgaa taatttccac gttttttcgt taatgttact tcttattaat tttattgtac
     1261 ttctcatgca gatcatatat ccttctaaat cttttttatg ctataaaaag ggggttctat
     1321 ctaactttat tattcattcc ccaccctttg cgcagtgagt cttcggtatc ttgttttatc
     1381 tgactggtag ttcttattat ttctccacgg tcatctaatt ctggaacaat tggatatttt
     1441 tctctgaaca agtctagttc tttcaccacg tcattaaaca aatcttgctt atcttcttgc
     1501 gtaagattct gtttaatata ctcatctaaa gcttttctaa gcaattcatc tcttgtcata
     1561 ttagtctcat acttttctac taaaactctg gaagtcgcat ttaacaaagt cgacagtttt
     1621 aaaggatgct tggtggaata aaccttatca aactttctga ttggtgcgcc aacttttttt
     1681 gttcttcctc tactctgtct ttcaacattg gaggaagttt ttatttcttg aacttggtgc
     1741 acttctaatt gcttattttc agatggtgta attgcttgct gctttttctt tgcttctgct
     1801 tcttttttta ttttggcgag tcctttgttg ttcccaaaaa tatcaagtcc tttgatgtca
     1861 gccaattact ccacctccgc ataccaattc tcgtgttctt ccaattcttt caaaatactg
     1921 ataaataatt cgtggctttt gcgatcccat tgttttaaga gacctttctt tgtcttctcc
     1981 atcgtaatac ctgatccgtc gtatcgtttt aagcgcgcat ttttgagtac aacattttta
     2041 atcaaatgtt ccccataaat ctcttgggct tgtttataca tttcctgatc tactgcgtca
     2101 ccgctttcca acatgaaagg aataacacca gcaacatata aatttgtatc aaattctttc
     2161 acaaaaaagt ccatatactc aagatattgc atcgcatttc tcatcgattt tacttgggtc
     2221 tgtaagacga cgattgccca gtccgcaatg tacatcgcgg atttactata tacagaaata
     2281 gaaggtggga catctaaata gatgacgtca aactcatcaa ataatggttc tagcttttct
     2341 ttcatatatt tgaattggga taatgaatca ttatattggt ctttgatcca atcatcatac
     2401 atttcaaagg acatatctgc tggaagtata tagaggttat tgattacttt atagacagcc
     2461 tctttaggtg gaagattgtt tatcaacacg tcagtcacag tattttcgta aacaatcggt
     2521 tcaccttctc cgcctccttc ttcgttagtg aagttcatat gcgttaagtt catcacatca
     2581 gaagtatttc cttgcatatc caagtcaatt atcaaggttc tttttccttc attaactgct
     2641 gattcaaacc ctaacatttg cgcgcacgta cttttaccta cgccaccttt aaaattacca
     2701 attacatatt tcttcgctac cacgttccta cctcttttct tttagcaata ttcatttgat
     2761 actattataa catatttatt tttagttact accaaaaaaa agatatatat gtactacctt
     2821 ataattaata agtaaaaggt agtacataaa taaggaaaag ttgaaatata ttgatttata
     2881 gctttcctca aagtaatgac gttatttaat ttatcgagaa gcagagaata ctcgcgactt
     2941 tagtcatgta gacgaatcag attttcgata aaaaagaagc cgtccttctt aagaacgaca
     3001 acaaatcact agattaattt tttcaactgt tcataaaagt tttcatgcgt tccacataac
     3061 aatactggaa taaccttgtt ttctataatc tcgtaagcta ctctatatgt tgtgcccgca
     3121 tatttgaacc cactagacca aatacctgat aaatccccag ttttttgttc acccttatat
     3181 ggatcaatcg caatttcatc ataaattaaa ttcaaaaatt tttctttcaa tggcttctct
     3241 tttagctttt ttaaatactt aatgacatgt tttgaaggaa cgatttcata agccaatttc
     3301 tgttgccaac tcctctttag tcattacttt agaattagta agtgtatctt cagcaatatc
     3361 tctaaaggaa gaatgcattt tgttttttct attcttaaat tctacaagaa tctcatcttt
     3421 atcgtagcct tctgcaatta tatcagacaa aatatcttcg ctaaaatcat aaaattcttt
     3481 ttgtggttca acaaattcat aaagaatacc attctctacc aactttgctt caacttcgac
     3541 tccattagga acattaaaat ctttaggtac tgtcaacatg attgaattgc cttgttttct
     3601 tgtttttgta atcatttaaa tccctcattt ctaacagtat gtaattactt agtaaataca
     3661 ttataccacg agataatgta tttacaagta attactgtga ctcgtaatgc gtccttgctg
     3721 aataaatttc aaccacgtgt tcatcttcat ctaccttata aacaacccgg tgttgtctat
     3781 tcaatcttct agaataccta ccttcatatg taggttttaa cttctcaaat gattgggtag
     3841 ggagataggg atcttccttt aaagtctgaa taaccttctc aaattgaggt ttcaaattag
     3901 actgtttgat tttctttaaa tcagctttag ccgagttttt aatcatcaca gaatagttat
     3961 tcattataag ttatcccaat caatttcatc aacattagta aatccactat catctttttc
     4021 tcgcttacga acaacaccca aagtgcctat ttgctcaagt aatagcgttt ctttgattgc
     4081 tttcaaatca tccaaaccaa taagcaccgc attattttca ctgcgctcac taatgatttc
     4141 aatttccgta tgattctcat ttacatcttt caacaactta taaaaatttt tccgtgctga
     4201 gctaggattt aagactgttt ttgccatatc tactccccct ctaatttata tctccattct
     4261 aacgtactta attaagtacg taaattcgat tgttttgttt aaattggagt accaaaacag
     4321 cattgtaaag tgttatccgt ttcctttatt tttattaaca agttttatca caggcttcat
     4381 atatttgatt ataacttcat cttctacgta gatatctgtt atcattacga catctgtact
     4441 atttcgattg agtactttca cttgatctcc agcattgatt ttccctctaa atcttttagg
     4501 aatgaaccaa ctatacatat gattagcatc accaaaatgt gcttttatcg cattctcagg
     4561 atataactta ttcaatagtt cattcttttt aattttcaaa acttcaaatc tatacttatc
     4621 atcatctgct aatctaaata aatcttctaa acgcatgttt tctaactgta agttttgaaa
     4681 atcttccggt ataaattttc ggttctgttg cgaagtttga aaatcaaacg cgccctctct
     4741 gaactccaaa tatcttaggc tgttattccc attaatacct tgatttcagt agacaccgaa
     4801 aagctgaaga gcgttccatt tcttcggttc tttttatata ttcctcgaat ggtctccatg
     4861 cccttaatcg tggaagaggc tgtacggaga ctttgataaa atttatt
//
LOCUS       DAFEIE010000109         4861 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFEIE010000109
VERSION     DAFEIE010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.115"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..440
                     /locus_tag="LP345_002677"
     CDS             <1..440
                     /locus_tag="LP345_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HBL1761418.1"
                     /translation="TFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKAASEKQEATR
                     HLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEIIQNGRTSQSV
                     RGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            456..605
                     /locus_tag="LP345_002678"
     CDS             456..605
                     /locus_tag="LP345_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761419.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            681..1274
                     /locus_tag="LP345_002679"
     CDS             681..1274
                     /locus_tag="LP345_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL1761420.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            1287..2186
                     /locus_tag="LP345_002680"
     CDS             1287..2186
                     /locus_tag="LP345_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL1761421.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            2189..2662
                     /gene="ssb"
                     /locus_tag="LP345_002681"
     CDS             2189..2662
                     /gene="ssb"
                     /locus_tag="LP345_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1761422.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFANQNGNR
                     EADFINCVIWRKPAETMATLAKKGGLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSTTSPSPTTFEQRDTNNGLDASQNPFGGQSIDISDDDLPF"
     gene            3028..3288
                     /locus_tag="LP345_002682"
     CDS             3028..3288
                     /locus_tag="LP345_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761423.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDQFTRLMGI"
     gene            3733..3939
                     /locus_tag="LP345_002683"
     CDS             3733..3939
                     /locus_tag="LP345_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL1761424.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            3939..4190
                     /locus_tag="LP345_002684"
     CDS             3939..4190
                     /locus_tag="LP345_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761425.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTTETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTELEN"
     gene            4206..4622
                     /locus_tag="LP345_002685"
     CDS             4206..4622
                     /locus_tag="LP345_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761426.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGACYIMK"
     gene            4604..>4861
                     /locus_tag="LP345_002686"
     CDS             4604..>4861
                     /locus_tag="LP345_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761427.1"
                     /translation="MLHHEVIRRIQKDFSCMEEMKYFVQNVEEQLYLESETSQTKVTV
                     SHNRLDVYKRRPESLKKGAELLRLETEKYVMNVYLEKSELVE"
BASE COUNT         1815 a          808 c          965 g         1273 t
ORIGIN      
        1 ctactttctt agctaatatc caaaaatttg tctctcactt gttggaagtc gtaccgggac
       61 aaatccagtc aacagatttt ggatcaacgt tacaagaggt gaaagcagcc agtgaaaaac
      121 aggaagcaac gcgtcattta ggtgtttgtc caaaatgtcg ggaacaagaa gtcttgcttt
      181 atcaaaatgt ggcggcatgt acgtctgaag cctgtgattt taaattatgg acaacgattg
      241 ccaaaaagaa actcacagcc acacaactga aagagatcat tcaaaacggc cgaacaagcc
      301 aatcagtcag aggactaaaa ggtcagaaag gttcgtttga agcaacgatc gttttaaaag
      361 aagactttac aacaggcttt gaattttctg aaaagaaaaa aacgaactat aagaaaagaa
      421 cacgccgcac tacaaaataa tgaaggggtt atcctatgcg aaatacaaca cacaaacaac
      481 aagaaatcga aaatcaaaaa gcaaaaattc gtttagaaca agagaaatta cgtgcaaata
      541 aaagaagact gcaacaatta aagaaccagc agcgcattca aaaagaaatc gaattagatc
      601 gatagacgtt aatcttgtta caaataaact actatgatat atttgatgta gtgtatttgt
      661 aacgaaggga ggggaagtaa atgcaagata aactgaaaga attgttggct attcgcgatg
      721 gaaatttatc tatgaaggaa gccaggaaat ttggaatcgc agcaaccact gtacaaagat
      781 tggtgaatca aggaaaattg atcaaagttg atcgtggtta ttatgtagag gatggtcatg
      841 gaatagatga tttattttgg cttcagcaac gattttccag gggaatcttc tctcatgaaa
      901 cgactttaga tatttaccag ctttctacga atatgccgaa attcattcac ttaacttttc
      961 cccatggcta taacgttgat cgttcaatta caaaagagca gcagttacaa tttcatttcg
     1021 tgaagaaaga agtttatgaa ctaggaaaag tagagggaac ttcctttcaa ggaaatccta
     1081 ttactatgta tgataaagag cgtacacttt gtgatatttg gaatccgaga tatgaatttg
     1141 aatatgaaat gaaattagaa gcattaaaag agtacatgga agacccattg agagatccaa
     1201 gtaaattaag agattacatg acaaaactac atgtagaaaa agaaatgaaa taccacatgc
     1261 aaagcttata ttgatggagg aaaaagatga caccgacaca atttgcagca aaaacaagaa
     1321 atttagcaaa gagtacagga ttaaatgcac agttagtgca acggcatttt atgatggatc
     1381 gtctaattga acaaatttct gaatcaaagt acaaaaatga cttcattttg aaaggcggct
     1441 ttttattagg atcaaaatat ggaatcgata gaaggacaac aattgatatc gatacgacat
     1501 ttagaaatag caaattaact gaagaaaaat tgaagagcat ttttaatgat ttaactagaa
     1561 aacccacaaa agaaggcatt gttttctcta ttcaaggaat gaaggaaaca agagaagccg
     1621 atttttatcc tggatttcaa attaaattgg tggctaattt agagaaagta cgtgtaccgt
     1681 ttaaaatgga cgtgacaaca ggagattcta tttatcctga agtagataca cactatcacc
     1741 aattaatgtt tgaagataaa aaagtggaga ttccagctta tccaacagaa caaattattg
     1801 cagaaaagct aagtgctacg ttcagctttg gcacagataa ttcgagagca aaagattact
     1861 acgacttatt taccattccg aaactagaaa atatcgatac gaaagagtta tacaaaagtg
     1921 ttcgaaatac atttacaaaa cgtggggata caaaaccgtt gtccttttat tatgaaagag
     1981 aaatggataa gatcagagga aatgactatt tggaaaagca gtgggaaaaa tatcgctcag
     2041 ttaacacgtt tgcgaattcc atttcattta cagatacagt caacgaaatt gatcacctaa
     2101 tgaaaagtgt gatcaaaatt gaaaatcaag aaagaaaacg gcagtttaaa agatcacaac
     2161 aaatgaatca agaaatggag agataaagat gattaataat gtgacattag taggacgctt
     2221 aaccaaagat cccgatttac gttatactgc aagtggcaca gcagtagcga cttttaccct
     2281 agccgtcaac cgaaatttcg cgaatcaaaa cggcaatcga gaagccgatt ttattaactg
     2341 cgtgatttgg cgcaaaccag cagaaacaat ggcgacatta gctaaaaaag gcggcttgat
     2401 cggtgttgtc ggacggattc aaacacgaac ttatgacaac cagcaaggac aacgtgtgta
     2461 tgtgactgaa gttgtagcag ataactttca actattagaa agtaaagcag cgacagagag
     2521 ccgtgcgcac gctgatcaat caaccaccag tccaagcccc actacctttg aacaacggga
     2581 tacaaacaat ggattggacg cttcacaaaa tccatttggt ggacaatcaa tcgatattag
     2641 cgatgatgat ctaccattct aagtagcatt ttctattggt tgcatttgct acggtttatg
     2701 ttataattta gtcaacaaaa agaattttca atctataacc aaaaaccact agctggcggg
     2761 ctagtggttt tcttttacgt ttctattata agaattaacg ggtaggctta ctgtctttct
     2821 tggcaaattt acaatcaagc catttgcaga tatagtgcgc ggctacttct gccatgattg
     2881 caaaaacaaa atcaaaaaga attttcaaac ctataacctc ctccccttgc cagattaggc
     2941 cggggtagca gacagcaaga ctattatagc ataattgaaa tattcaaatg attggatttt
     3001 tgctataatt ttagcgaggt gattgtgatg aacaaatatg ttggtttgct tgataaaatc
     3061 cgagtaataa aaacgcaacc gttattggtt cgctttactt tacaaacgat tcatgaatcg
     3121 attaattgtg tagttgcaga tattgaaatt atcgataaat tgctaattat ggatgatgga
     3181 aaatacaata ttgccgtcac aggtcacttc aataaacgaa accagctagt tattgctagc
     3241 atgtatgtta gaaatcccga tcagtttacg cgattgatgg gcatataaaa aaagaagagt
     3301 tgcaatccta atgtaggact gcagctcttt ttgttttaca tagaaacaag aaaaatgaaa
     3361 aggccttttt aggaaggcgc gagcgccttc tcaattgaaa aacctctctc actccaaccg
     3421 ccaccgccgt tcgagaagaa aggaagtgaa cgttgcacgt tcactaagat aaagggtctt
     3481 gcaaagcaag acaaaataga aaaaacttcc tctcaccaaa aggttcgttc ctgttcgtta
     3541 tctctttatt gatttgccag accggcaaca agttgccttt tatcaccaaa aagcgacaag
     3601 gacaagggta aatggcacgc tgcgcgccct tgtccttgtc gcttttcgtt gattcattct
     3661 ggccaacaaa tcaataaaga aagaactaac gaaaggaagt aaaacctttc ctaagaggag
     3721 gcagaatcaa tcatgcgaaa gaaatttgat tattggggtg ttcccttcag cgaattattc
     3781 ccaaactatc atgcaccaca tactgtcgaa tgcgattgtg gagaaagagc gaaatgtatc
     3841 aaaagctatc gtttgtatca atgtccaaca tgcgggaaaa aatatacctt gtcttatggc
     3901 gattatattt tgattgatga gaaaggaaag aaacgttgat gaaaacacaa cacaaattat
     3961 tgactgtaaa agaagtcgtt caaattttgg tggacaaaga agtcatttct gaaaaagtag
     4021 cagaagcttt acttattccg cggtactgga cgacagaaac ccctttagta gaggatgcac
     4081 cgactatgct atttgaagac ctagtgaaga ttgcaggata tgaactgcat tatcaagaaa
     4141 acttggaaac ttatgaaaac gaatattggt taaccgaatt agagaactaa aaaggagaaa
     4201 aaaatatggc tcaaaattac tatgacgaat ttgtcaaatt acctttggat aaaatggcac
     4261 aaaaaatgga ggatatgaca ttcctataca atgagacacg tgttccaaaa aaacattata
     4321 aggaaagatt gtcggtagct gtggaagaaa tgattgaatc aggtgtcgaa atgaatctca
     4381 ttgcgacgta ttatcgaaca ctggaagaac tgaaaaagca aaatgcaaaa tggtttttcc
     4441 aagccttact atgcttggaa gtaggcgtca aaccaagcac aatcaaacct tctgaatacc
     4501 aagctttaga actaacgtat gcgaaattta tcgaaacgaa aaaagctaag actgtttcaa
     4561 gtgaatggtt agattatttt gaaaatatca ataagtatgg cgcatgttac atcatgaagt
     4621 aatcagacgg attcaaaaag actttagttg tatggaagaa atgaagtact ttgttcaaaa
     4681 tgttgaagaa cagttatatt tggaaagcga aacgagtcaa acaaaggtca cagtcagcca
     4741 taatcgttta gatgtgtata aacgtcgtcc tgaatcatta aaaaaaggag cggagcttct
     4801 acgactagaa acagaaaaat acgtcatgaa tgtttaccta gaaaaaagtg agttggtcga
     4861 a
//
LOCUS       DAFEIE010000110         4807 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFEIE010000110
VERSION     DAFEIE010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.116"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP345_002687"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP345_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBL1761428.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="LP345_002688"
     CDS             complement(3250..3768)
                     /locus_tag="LP345_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBL1761429.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1579 a          786 c          730 g         1712 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcggta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa
     3961 tatatttctt ttgtagtaaa atcggactgg tttgcatatc attttcttcg taaatatcaa
     4021 aatcatgtta actactatca attactaata aaaactacca ctttaagcgt taagaactgt
     4081 taagtttagt taagtgagga tagttcacaa aatccattgt taaacttcac gaaagtggta
     4141 aaactcaaaa tgctttatat aggattacag catcgctctt tcttcgattg cgcgttgggt
     4201 aaaaaatatt atgaagtaaa aattgacgat gacacgttcc ttacggctca tcagatgaaa
     4261 cagctacaaa aacgaaatga tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca
     4321 tattcacgcc tcgctcgacg aactattaaa ggtcaagatt tacctgaaga tcatcctttt
     4381 taggaaattg aagcttttta tgttgcacaa tgcatttata atactacaat gatgttttca
     4441 ccagatattc ttctagggtg cggtgtaatg aaacagatac acttgcaaaa gaaaattcac
     4501 cgcgaattta ctaaaattat gaataattat gttaatcttc cgaaattttt ttccaaaatt
     4561 aagggatcaa gctggtgtta tagattgttt aaggttggca aaaaaataac ttctttttaa
     4621 acaattatag aaaaccgata ctctgttaag ttggttgaca cggtgtcgat ttttatgact
     4681 ttcttattct gaaacttcac taacggacag tacctaaaaa gtctatagta tggacgttta
     4741 cgagtactat tttatcaaaa atgctgctca tttcaactta tatgttttag tgaactaccc
     4801 ccactta
//
LOCUS       DAFEIE010000111         4791 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFEIE010000111
VERSION     DAFEIE010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.117"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(75..1073)
                     /locus_tag="LP345_002689"
     CDS             complement(75..1073)
                     /locus_tag="LP345_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBL1761430.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1148..1444)
                     /locus_tag="LP345_002690"
     CDS             complement(1148..1444)
                     /locus_tag="LP345_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL1761431.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1437..1730)
                     /locus_tag="LP345_002691"
     CDS             complement(1437..1730)
                     /locus_tag="LP345_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761432.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1876..2427)
                     /locus_tag="LP345_002692"
     CDS             complement(1876..2427)
                     /locus_tag="LP345_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBL1761433.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2601..2900)
                     /locus_tag="LP345_002693"
     CDS             complement(2601..2900)
                     /locus_tag="LP345_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBL1761434.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEIGTLPKDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2927..3235)
                     /locus_tag="LP345_002694"
     CDS             complement(2927..3235)
                     /locus_tag="LP345_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBL1761435.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQLPLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY
                     "
     gene            3540..4223
                     /locus_tag="LP345_002695"
     CDS             3540..4223
                     /locus_tag="LP345_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761436.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIE
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4260..4757)
                     /locus_tag="LP345_002696"
     CDS             complement(4260..4757)
                     /locus_tag="LP345_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1761437.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1424 a          908 c          700 g         1759 t
ORIGIN      
        1 taaaaaaact gattctaaga aaattaaata atttttctca aaatcagttt ttctttgata
       61 aataatattt tcaattattt aatcatttga aaattgttag tcattccaat acgttgagaa
      121 attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt gtttccatca
      181 tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat tagatctttc
      241 atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg agaatcatac
      301 aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact tgaaattcct
      361 gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc ttctactact
      421 ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa ctgttgattt
      481 tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg cgttaaataa
      541 actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa atattctcca
      601 gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt tccatcttct
      661 gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc attaatcacg
      721 gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta gcttttatat
      781 tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga agctttattc
      841 gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga acttgcactt
      901 gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt tttacttttt
      961 ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt ctcagatgta
     1021 caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt cattatattt
     1081 ccccctttca atttctccct cacgtactta ttctatcaga caattaattg atctaaatgg
     1141 taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag cggtctcttc
     1201 cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc
     1261 gataagttct cattattttt gggctattag tattattttt cttagttaga gctatgagtc
     1321 caactatgat taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa
     1381 gcatatattt atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag
     1441 ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa
     1501 ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg
     1561 attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct
     1621 cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag
     1681 tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc
     1741 cctgttattt tttacataat gaaaatagca tattactggg tacattgata attcatataa
     1801 catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca
     1861 tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc
     1921 attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta tcaatacttt
     1981 ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt gttcataagc
     2041 cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga ttttcttttc
     2101 tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa gaaatacccg
     2161 aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag taaatcctaa
     2221 ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc
     2281 tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc ctttgatcgc
     2341 ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg
     2401 tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt ttgttcaagc
     2461 acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt
     2521 ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa catttcgcaa
     2581 tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca aaccaatcgt
     2641 ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt aatgaaataa
     2701 actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa
     2761 cgtggtagat gaacatcttt aggaagtgta cctatttcaa tttcctcttt ttccatcgta
     2821 acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt ttccagtact
     2881 tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag tattcttctg
     2941 gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga gacactgatt
     3001 tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct tcttgacgat
     3061 gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga tagtctaaag
     3121 gaagttgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt aattccaccg
     3181 gcaaactgtc cattactccc tttgtgacat aacgttgtcc tttattttga aacatttctt
     3241 ttccctcctt tgctataaaa atagcccaat cttctattaa agaagattgg gcttcatgga
     3301 tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact acacaattat
     3361 taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc gtggtgctag
     3421 ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata
     3481 tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat ggttacgtcg
     3541 tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat atccccgatt
     3601 atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat cgtgttttaa
     3661 aaggcatcga aatcggttac atcgcttctg aaaaggatcg gatcatcgac tatttagccg
     3721 ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt gattatttag
     3781 atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt gcacaacttt
     3841 cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat ggttttcggg
     3901 tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta ccgattctag
     3961 atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct tacttgtatg
     4021 acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt ggtaccttgt
     4081 ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc gatgatcttt
     4141 ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa ggaaagcgaa
     4201 ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag gacgtttttt
     4261 tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg aaaatgtttg
     4321 atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg atttttttca
     4381 taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt cgcttcatcg
     4441 agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag ccgttgaatc
     4501 tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg atgatcctta
     4561 ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc agttgtcaat
     4621 tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa cgattcataa
     4681 aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa atacgctagt
     4741 gtgatttgat tgttcatcta actcctcctt ttgacatagt atactataaa t
//
LOCUS       DAFEIE010000112         4616 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFEIE010000112
VERSION     DAFEIE010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.118"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(15..962)
                     /locus_tag="LP345_002697"
     CDS             complement(15..962)
                     /locus_tag="LP345_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBL1761438.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1140..1943)
                     /locus_tag="LP345_002698"
     CDS             complement(1140..1943)
                     /locus_tag="LP345_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBL1761439.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2089..3003
                     /locus_tag="LP345_002699"
     CDS             2089..3003
                     /locus_tag="LP345_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL1761440.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3051..3521
                     /locus_tag="LP345_002700"
     CDS             3051..3521
                     /locus_tag="LP345_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBL1761441.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3606..4214
                     /locus_tag="LP345_002701"
     CDS             3606..4214
                     /locus_tag="LP345_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBL1761442.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4348..4548
                     /locus_tag="LP345_002702"
     CDS             4348..4548
                     /locus_tag="LP345_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1761443.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1511 a          716 c          912 g         1477 t
ORIGIN      
        1 attgttttca gctattaata tcctgcagac aattttactt gattggtttg aagctcatgg
       61 gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt ttgaaaatca
      121 ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca aagaggatga
      181 tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag ttgctggtta
      241 tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac attgatgaat
      301 acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt tgtttcctcc
      361 gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt tagttgattt
      421 aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat tccatagcag
      481 ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc agttccaatg
      541 attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa ccatttcatg
      601 tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat gattcctaag
      661 acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa aatatgtttc
      721 tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg gacccatttc
      781 aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa actgatctct
      841 acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg cgctatagta
      901 tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat tctttctgac
      961 atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag aactttgaag
     1021 cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc tgtgacaaaa
     1081 aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt ctttatttct
     1141 taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa gattcctgca
     1201 aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat tgttgcaatt
     1261 atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa agtagctttt
     1321 gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa agtgatcagc
     1381 agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat ccaaagtggt
     1441 atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt taaagattca
     1501 ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt gcctgtatta
     1561 ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt ccccatcaaa
     1621 tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa gataatggag
     1681 tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt ttggattgta
     1741 aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt taagacttga
     1801 aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag atagacaatg
     1861 gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat aaaggaactg
     1921 ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc acttgcaatt
     1981 ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg attggtgaaa
     2041 tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat ggaggaagga
     2101 atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt ggttttgaat
     2161 gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt gtctcttgtt
     2221 tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta cggggcacaa
     2281 aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg tttagaaata
     2341 ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt aaccgttgaa
     2401 gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct aacagtagca
     2461 gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga agcagatgaa
     2521 agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc ttcggtaagt
     2581 gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga tccagttatt
     2641 acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa aaaagctgcc
     2701 gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca agaaattgaa
     2761 gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag cgaaaagata
     2821 attattttcg acggacatat tgattttgaa gatcagctac taagcgagat tgaaaagata
     2881 tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt gacgatccaa
     2941 gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga tgaaagttat
     3001 tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc atgaagcagt
     3061 atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta gtctatctct
     3121 tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca cgccaatatt
     3181 ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta ttgtttgctt
     3241 ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca catgcactta
     3301 ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac atgggggcaa
     3361 tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc atcactcaaa
     3421 ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa gaaactgagg
     3481 tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa ttgaagaatt
     3541 tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg aggaggaatt
     3601 tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg gaaccttata
     3661 ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat gtgacgaatt
     3721 taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa gaattattat
     3781 ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat ggtggcggac
     3841 atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc gaacctacag
     3901 gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt aaagaagaat
     3961 tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta atggaaaatg
     4021 gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa ggaaagacac
     4081 caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa aatgtccgac
     4141 cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac aaacgtttcg
     4201 aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt ggaaaataaa
     4261 agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa ggttacttgc
     4321 aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg gttcaacaat
     4381 gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt tcatttctca
     4441 gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga attcacgatt
     4501 gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata atttgttgaa
     4561 taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt ttttag
//
LOCUS       DAFEIE010000113         4468 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFEIE010000113
VERSION     DAFEIE010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.120"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(312..842)
                     /locus_tag="LP345_002703"
     CDS             complement(312..842)
                     /locus_tag="LP345_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1761444.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1024..1680)
                     /locus_tag="LP345_002704"
     CDS             complement(1024..1680)
                     /locus_tag="LP345_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBL1761445.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1807..2280)
                     /gene="dfrF"
                     /locus_tag="LP345_002705"
     CDS             complement(1807..2280)
                     /gene="dfrF"
                     /locus_tag="LP345_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL1761446.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2699..2917)
                     /locus_tag="LP345_002706"
                     /pseudo
     CDS             complement(2699..2917)
                     /locus_tag="LP345_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2948..4162)
                     /locus_tag="LP345_002707"
     CDS             complement(2948..4162)
                     /locus_tag="LP345_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBL1761447.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         1373 a          944 c          658 g         1493 t
ORIGIN      
        1 ttttttgaaa tcaactgtct ttctcatatt tactattcaa ttttcatagt gatataggta
       61 caatttatat cactactgta aaaatggggt tttgccttat aaatacagcg ttttccgctt
      121 gttagtgtat agtgtttctt gttttttgtg ccccccttgt tagataacgg gggctttgaa
      181 cggctcgcaa gctcgccgaa ccgccgaagc gaaccgcccc cttgcaagca tggcggaaaa
      241 atcttaagga ttttcccgcc aacgtggtcg gatcgctccg tcggtttaac agcttttctg
      301 tttctctcta gttatctacg catataaatc aaatcggtta ttccgttata agtctgtgtt
      361 ttacaaagcc ttaactttat ttccctgtct atgttgccca aaagacgaac cccatttcct
      421 aacagagtag gaataacaga aatgtaatat ttatcaatca tatttttgct taccaactgc
      481 tgaacaagat ttgctccgcc acaaatccaa atatcctttc ctgcttcttg ttttagccgt
      541 tccaataata aaacaggatt ttcacttgta aaatgaattt gttgggaaga attgcactct
      601 ttatgtgtta atacataagt tgtaaattta ttatataccc attcttgcgg agaaagttca
      661 gtaacaacct gatgagaagt attccacccc attaagacag tatctatatc tttggtaaat
      721 tctgtataag tgtcgatgtt ttcattgtca tttccatgac catttagcca agctactcca
      781 ccattaccgt ccgcaatata tccgtcaagg ctcatggcaa taaataaaac tacttttctc
      841 attttttctc ttttataaat acaaacagga atttatttct cttttttact cataagggaa
      901 caactgattg ctacaaataa acccattaaa atccatggaa atgctgctct tataaaatca
      961 ctaaccatac tttattcctc cttaaattcc aatttcctta gttctacaaa ctgaaatttt
     1021 tgcctatgaa tgtatcttgt tctttatacg caaacaggct tctgtgtgca taatccaatg
     1081 tcttgaaaac ggcatttgaa ttagtccaca aatatcttta ttacaccaat aatcaatcag
     1141 ccaaattgct ttttcattgt cgtttactac attcaacgat tctaagtatc cttttctttc
     1201 tttcggtatt tttcttttca attcatcata agataaccgt tcaagcattt tctcagtgct
     1261 ttcccatact tcgaaaatat ataaatataa ttcttccaga ttaagctgtt ttgaaaagtc
     1321 tgcaatctgc tgtttcatga gttcatttcc tgttgtaatg ataggtgaat tgatacgctc
     1381 ttgataattg cctgcaaaaa atacttgttc atcttcattt atcactgtat gcacaactat
     1441 atcttcaatg cggaaaatat gccaaataga ataagcaatc gtcttactat gataaccatc
     1501 agcgtttatg aaggggattg agttaaaatc ttctctgcat aattcttctt tgaaagatac
     1561 taaggtttgt attaactgac ttcgtaaagt aagtaaagta tcaatacccc tcttataagt
     1621 atctttcttt tttatttgtg cctgcattgt tttattaagt tcagaccatt ccttattcat
     1681 attcaatcct ctctcaaatt ctgattttat cgccccatac aaactggaat ttgtcttaca
     1741 acaatttata tatgcataaa aagcaatata tttatgaaaa caccctaaat ccaaaattta
     1801 ctcaattcat tttttcctta cataaaatgt tctcgtatat ttcacttcct caccaagtgt
     1861 ttcccctatc aaaacttcaa aatcattgat atcaaattct ggaaagaatg tatctccatc
     1921 ttcaatattt aaatctactt ctgtgatata cattttatct actatttgca aagcttcctt
     1981 aaatagtcca tatccaccag atatgtatac atctcgtcct ttagccaata ataatgcatc
     2041 ttctaatgat ttaactgaaa ctaaattatc tccttgatac tctgttgtgg tggaaacaac
     2101 aatattcatt ctattaggca acggatgacc gatttcttca taagactttc gccccataat
     2161 aaccacatta cccgttgtta actctctaaa ttgcttttgt tctcccttta ttttccatgg
     2221 tatattacca ttcttgccta taacattatt ctttgacctc gcaacaatca aacctatcat
     2281 ctatttcatc ctccataata tgatgtcgta cctgtgattc catcaagtgc accacatctt
     2341 aacaaactca aaattatctc gaactaacca gctcgacaaa ttcctttttt gtcttcatct
     2401 gcattatatc atattgttat aagcattgcc atttcttttc tgcttttgaa aagttactta
     2461 tcagcctatg ttttgtaaag ggtgatattc agcatttctc acgcaacaag cccttgacaa
     2521 accatagact aataagtttt aaggtaatca agcagaaatg aaatagtctg ctgtttcacg
     2581 gcaacaaaaa agagatacca acacacttat gtagtatctc ttagtctagt agcaatattc
     2641 ttttgtttgc aagcaggtaa acatgggctg tttcttaata tctttttgtt tgggaaacac
     2701 ctttttccca tcctttcacc gttgccatct ctgctgcgca caatgccaca gggataaacc
     2761 atagcaaacc gcctaataac aagaaaaata ctaagctgaa gcctgaggtc gcgaatgtgg
     2821 gatattcata taatgaaacg accattgaga tggtcatagc caaaaagcca aagaacgtta
     2881 atttttttgc aggaattttc gttttgcttt gttgcatgaa tcttcctctt ttctatttga
     2941 atttgtttca attgagtttg ttgccaaaga agaaaaagtc caatccttct tcttgttctt
     3001 cttttgtagt agtgatcgtt gtaaagtgca tcgccgattt taaaatcact gttgtcagca
     3061 cataggcata cacggcagta atgatgacac caatcacttg aatccctaag aagtaccagc
     3121 tgcttggatt cgttagtaaa tggctgttag atgcaaagat ccctatcaga atcgtacctg
     3181 tgaatccgcc catgccatga acaccccaca catcaagtgc atcatcccat tgtttctttt
     3241 tacgaaaatc aacagcagca tgacagacga tacccgcaat gatcccaatc agcatggcac
     3301 tttttgcttc tacataaccg gcacaaggcg taatggctgc caatccagca acggatcctg
     3361 ttagtacgtc gacaaaatca aagccatttc cttttacttt tgcaatgatc agccaagtaa
     3421 tcatcgcaaa tgcaagagcg atgaatgttg aaccaaatgc attgactgct tgttcatctg
     3481 ctcgaagtgc accaccggaa ttaaaaccga accagccaaa ccaaagcagt cctgtaccga
     3541 tagcagctgc cataagactg ctatgctgac ttctttctcc taaaggaatc tttctttgac
     3601 caagtgtgag gatacatgct aaagagccga atccagctgt cgtgtggatg actgctccac
     3661 cagcgaaatc tctaaatccc atctgatcca aaaatccgcc accccatatc cagtggcaaa
     3721 cagggaaata aatcagcaga ttccaaaaaa taacaagtat aatatagcct tttaaattca
     3781 atctccctgc aaaagctcct gtcatcaaag gaacggtaat cacgataaac atcagttggt
     3841 aaagaaagaa cattaaaaat ggaatcgttg caccatgaaa catgttgggg aagcttgtaa
     3901 catgtctcat caaaaagaaa tctgccgggt ttccaataac accgccgata tcccgtccaa
     3961 aggccaatcc gaatccacca aatacccaca taatcgttgt tatcccaacg gagagaaaag
     4021 attgagacat gatcgttagt atattattct tccgtgctaa tccgccgtaa aaaaaagcta
     4081 gaccaggagt catcaggcaa accattgctg tacataaaat catgaatgct gtatctcctg
     4141 tattgatagg taatgtattc atttttttcg cctcctttct acgattacga gtataaaaga
     4201 aggtgtagtt gtttttttct tctgtttttt tgaattaata cttgcattta taaaagacag
     4261 acaattaata aaagcttgat gtgttgtgct ctttttcgtt tttcacacaa ataaagacaa
     4321 aaaataaacg gtcttctttt tatagaaaac cgtttatttt cgtctttttt tatttttaaa
     4381 gatatttttt cataaggaat aaagaatact tcatataaaa tatataaaaa agaaccgcag
     4441 cgagtgtcgc tacggttctc aaatttgt
//
LOCUS       DAFEIE010000114         4430 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFEIE010000114
VERSION     DAFEIE010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.121"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(543..2048)
                     /locus_tag="LP345_002708"
     CDS             complement(543..2048)
                     /locus_tag="LP345_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1761448.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="LP345_002709"
     CDS             complement(2045..2731)
                     /locus_tag="LP345_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1761449.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="LP345_002710"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="LP345_002710"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBL1761450.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DAFEIE010000115         4402 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFEIE010000115
VERSION     DAFEIE010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.122"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(99..1619)
                     /locus_tag="LP345_002711"
     CDS             complement(99..1619)
                     /locus_tag="LP345_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL1761451.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(1862..2047)
                     /locus_tag="LP345_002712"
     CDS             complement(1862..2047)
                     /locus_tag="LP345_002712"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL1761452.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(2031..2213)
                     /locus_tag="LP345_002713"
     CDS             complement(2031..2213)
                     /locus_tag="LP345_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761453.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            2454..2672
                     /locus_tag="LP345_002714"
                     /pseudo
     CDS             2454..2672
                     /locus_tag="LP345_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3167..3766
                     /locus_tag="LP345_002715"
     CDS             3167..3766
                     /locus_tag="LP345_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1761454.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            3830..>4402
                     /locus_tag="LP345_002716"
     CDS             3830..>4402
                     /locus_tag="LP345_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HBL1761455.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT         1403 a          799 c          785 g         1415 t
ORIGIN      
        1 ataattcagt agttttgagc gtaagcgtgt catagaatgg tacctaaaca caaatagccc
       61 gatttgatac actcaaatca ggttatttgt ggcttatatt atttacagat ttcttgtatc
      121 tgctgattcc atggcaaata agcgcgtagc gcttcaggtg tcatcgaaga cagattggga
      181 atctctgtaa aaagatgatt taaatatttg cggatgttta acccattcgc aacagctgtc
      241 tggataatac tcaatataat tccatttgat ctagcgcctt ttaagctttt agaaaatagc
      301 cagttttttc gaccgatcac taactctttg atggcacgct ctgctcggtt atttgaaagt
      361 tccaagcgtc catcaagcaa cacaatctga agtccgtctt tatgattgac tgcgtattga
      421 accgcctttc caagctgcga ttttggcaaa taagcaaaac tctcacacca atgaaaaaat
      481 tcagtcatca caggctgcaa cgtttccttc ctcgctacaa acctttcttc tgcgctaagc
      541 ttattaaagg tccgttcgat tcgaaacatc ttgtcacaga agtctaatcc tattttggca
      601 tgactttttg gggacggttg tttacccaat gcttcaaaaa actttctgcg aacatgcgcc
      661 caacaataaa cattgtttac cggcagcttt ccataggccg cgtaaccatc agtatgcaag
      721 aaaccgctaa atgattctaa aaaacttttt ggctcatcaa cggaacgcga atttgcgtgc
      781 tcgtagagca caacttgttt ttcttcgctt ttacctgaag catataacca gtaaaaggtc
      841 ttttctttat gagtattcaa tacccgatag cttgtctcat ccgcgtgtaa gacctcctga
      901 ttgcttaatt cttgatgaag gcaattgtag attggctcta aaaccatttc acttaccttg
      961 atatgccaat tagtgatttt tttacgatca agagggaaac caagtgcatg ccattctttt
     1021 tcttgtcgat atgccggcac ctttttaaca aatttttccc aaatactctg tgtcacaatt
     1081 gaagaggaac ctagactatt attgatcaac ggtttaggaa caggcgcttt tttgattttt
     1141 gtttctccta atgcttcaca ttctctgcaa tgataggcat gttggtagat gacttgtttt
     1201 tctatatggg caggaacata caatggctct tctctaagcc ttgtcgcacc gatatcatgt
     1261 aaagtatgac cacagtcttc acacaaacaa tcggcacctt ttaattcata atgaatagga
     1321 acttcaggca gaccttctaa tgaaagtgct ttgagtccct tgcgttttct gcgtttaaaa
     1381 gaagataccg taatgggttc ctggctttct tgtccagtgt gctctggttc attaaaagtt
     1441 gagtcgtcta ataaatcgat ttgcccatct acgggtggtg tttctttttt tcgtccaaac
     1501 aagcgtcgat tcatttcagc aatttgttct ctaagaagag tattttcctg ttgctggatt
     1561 tcaagcaact gtgttaattg cttgatttgt acaagaagtt cagattccat ttttgtcatt
     1621 tttacaccac cattctagcg attttcttac atctattata ccattttatg acaacgaaaa
     1681 acagacaaaa tccttgattt aacaaggttt tcgtctaata tatcgcacct tttttcgttt
     1741 cttttagcgt acatttttct tcgattgaaa ggccagtcag taagacttct tttctggaac
     1801 gcggccattg aaggtaccca ctttcaaatc ttttgtacat taatacaaat ccattttgat
     1861 cctagtaaag agccttgaag cgatctttct tcgtaccgca aaataagaaa agcgcttgat
     1921 cgtaaacatc aaggtcatat tcttctataa cgaaagctgc tagtccatca attccttttc
     1981 gaagatctgt ttttccacaa acgataaaaa tatgtttcaa tgcagttgca tcaatgagca
     2041 ttggcattca actcttttaa caaggtatac aaaagatatt tatccattcc attataaata
     2101 aatatttcct tatcttccga tttgattctg caagctagtt ttggcttggt gtcaatttgc
     2161 gatttttgag ccgcacttga aaattgaact ggtacaatat cttttttatt cattcgtttt
     2221 tctccttcta tatttgatag tttaattata gaagaaagat aatcggcgta cgagatacta
     2281 tcctatgaca cgcttacatt taatttaata ttttgcctca aattagccac actttttata
     2341 gaactaagag gaaaaatgaa gttttcttcc tattaatata gttgtttgaa atcttaaata
     2401 tagcgtttta cgatgtaatg ggaagtatgg tgaataaatc aactatgttc gtacgaagca
     2461 tttactcaac taatttaatc gaatctttca ataaacaaat caagaaatac agccaccgca
     2521 aggaacagtt ccaaaatgaa gagtcgatgg aacgtttctt agtctcgtct tttgatactt
     2581 acaaccaaaa attcctaggt cgcagtcata aaggtttcca acaggccgaa ggcgagctcg
     2641 aacaaatgct gagtcaaccg atggagaatt agaaacaatc tacagtaggg aagaaccatt
     2701 gacacaaaat tattgacgct cccaactaaa agtgtcaaaa taatgatgaa atcatttagt
     2761 tcttataaat tagaaaagag aaaataaata ttccatatct actttattgg atccgtaaca
     2821 tgactaaatt ctgaatactt tttaaagctt atcatttggt aaaactgaat ataagttaat
     2881 tatatagact gaaaattttg aattttcaga atagaataac ttaaaagtac tgacaaaatt
     2941 ttttaaaggg gcaatattaa tgttctgaga taatcaaatc ctaccgaaaa tatcaaaaat
     3001 ccaatgtgac acaatcagat tgtgtctcat tcgagggaat cacacaatcc cacgtggctc
     3061 taggcagaat tgaatttttg cttggggctt tttccttata ttgattttga atgagactta
     3121 ttatatgtta taatgcaatt aagtatcatt ggagagggcg aagaaaatga agacggtaga
     3181 acctattcga gacaaaaaaa agatcgatgc gatgaaggca atcttggctt cgggaaaata
     3241 tggccaacga aatttggttc ttttttcgat tgggatcaac accgcctatc gcatttctga
     3301 tttgcgtcaa ttgaagctgg ccgacgtgct ggaaatttca cgcggtcgcg tggtggtcaa
     3361 agatcgatta gcgatgaagg aacaaaaaac agctaaacat aattcggtct atatttccaa
     3421 caaattgcga aaaacgattt tggagtacgt tcaacaggaa tttcctgatc aactccttca
     3481 gcaagatttt gacggttatt tgttccctag tcgaaaaggg acgaatgaac cgctcaaccg
     3541 ccaaagtctg tggcgaatca ttcatgatgc tggcacggca atcggattga aagacattgg
     3601 cccacattcc atgcgaaaaa cgttcggtta ctttctctat aaacagggga ccaaaacaga
     3661 aatcattcag tccttgttga accattcttc tcagcgcgaa acattgcggt atattggtat
     3721 tacacaagaa gacaaagata cagctgtaaa aagcttagat ttataatata aaagttaagt
     3781 ttaaacatgg atagttttaa attagtagat tgagtgttgg gaggaaagaa tgagtacatt
     3841 atatattata ggaaacggtt ttgatttaag tcatggttta aaaactagat acactgattt
     3901 ttcaaaatgg gttgaaaaaa gtcatagtga aatattcgat aaaatagaca caatgataaa
     3961 tgaaaataat gaggtgagaa gtacagctga tgataagata ggttggttta attttgaaag
     4021 tagtttgcat gagttaattc aaagtccagt ctttgaagat tatgtagaag agtctaagga
     4081 ttatctcata ggttatggac atgaagattg gtcagattct gcccatcatg attttcaaaa
     4141 tatggtttat gattatgttg tttctctaga agaattacaa caacttttca aggaatggat
     4201 acgcaaagaa atacagccga caatagaaca taaaattcca aaataccaat tttcgtccga
     4261 tgtactattc tttacattca attatacaga tgttttggaa attctataca agcaaccgaa
     4321 agaaaacata tatcatattc atggcagtta tgacgatata ataatcggcc actccgagaa
     4381 ttttgacaac tttataggag at
//
LOCUS       DAFEIE010000116         4316 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFEIE010000116
VERSION     DAFEIE010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.123"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            148..1137
                     /locus_tag="LP345_002717"
     CDS             148..1137
                     /locus_tag="LP345_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBL1761456.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="LP345_002718"
     CDS             1134..1553
                     /locus_tag="LP345_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761457.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1532..1870
                     /locus_tag="LP345_002719"
     CDS             1532..1870
                     /locus_tag="LP345_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761458.1"
                     /translation="MVAILEVRCDMDKIDLREETVNRIEVMYERLADYLNLSDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQI
                     SVINSKEKGM"
     gene            1874..2236
                     /locus_tag="LP345_002720"
     CDS             1874..2236
                     /locus_tag="LP345_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761459.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPNEYDGLLGVIPSKK
                     SQMNESKFMSIFNDVNLR"
     gene            2458..3864
                     /locus_tag="LP345_002721"
     CDS             2458..3864
                     /locus_tag="LP345_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBL1761460.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQTNIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDVHEYKEIMSEISELRQTAVKERESVSDELGYISRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDIVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKKAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
BASE COUNT         1505 a          605 c          988 g         1218 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gttatcgtca atttctgacg atcagcaaca cgaaaaatca gtggataatg agtggcttgc
     2101 tgatgaaaaa tcagcgccaa gcgaacgaga ttatcccaat gaatatgacg gcttactcgg
     2161 agtgataccg agtaaaaaaa gtcagatgaa tgagagtaaa tttatgtcaa tttttaatga
     2221 cgtgaattta cgataagcta ttattttgcg tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacagcga aatccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtctaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaacaaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat cgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaattg gaaccacagc gagaatttat cgtgcaaatt
     2761 ggtactcttg atgattttcg tactactcgt gatgatggtt cttctactgg catatcggaa
     2821 caacaagcag aacaaaatcg agtgattgcc aacaaaattt tagttgagta tttcaaagaa
     2881 tttaaagaac ggaatcctag tttatccgtc tacaatgctg ttattcataa tgacgaagta
     2941 agtccgcacc tgcatttgaa tattgttcct gttgctgaag ggtataaacg gggtgttcaa
     3001 aagcaaccaa gttttaacaa agccttgcaa cagcagggtt tacgagcaga taaagagaat
     3061 ggtcgagtga tttggaataa ttttaggaat caggaagttg agtcaattga acgtttgatg
     3121 gcagattttg gttgggagcg tgagttagtc ggtactaaca aaatcaaaga tgttcacgaa
     3181 tataaagaaa tcatgagcga gatttcagaa ttgcgtcaaa cggccgtaaa agagcgtgag
     3241 agcgtttctg atgagttggg gtatatttct aggcaaagag aagaaaacga gcgagaaaag
     3301 gctctggtgg cttctgagag agcaaagatt gaagaagaga agaaaaatat gctgaatgta
     3361 aaaaaagaga tggcggtcat tttccaaaaa gatattgttc ctttagaaag tttcaagagg
     3421 cttcctgatg gttcgtatca tttatctggg aatgattttg ttgatttgta tcaacgagct
     3481 acgagagcaa caaatgccaa gagaaatgct gataacatga gtgagcaata tttacagatg
     3541 cttgagcaaa atacagaatt aaatgagtat gtagctacat tggaagaaga gcgtcatttg
     3601 tctggtagaa aacaattagc agatttacaa gtggaaaata aaaagctgaa agaagaaaat
     3661 cgctctttac gccagcgttt agagcgatta aaaaaagcat ttcaaaaatc gatcactcgt
     3721 ttgtctatcc gttttggtct tgcagaaaag gatatggggc tttctgagga attagaagta
     3781 ttagagcagg agaaaacctt attttatcgt caaaacgtct cacagcataa attagagcgt
     3841 tctgaagatg agatcgagtg gtagttacga tgtgcagtca acggtaccgg aggcggtctg
     3901 tgccgaggat aaggagttga cggctaaacc actagcctat taagctgaca tttgctaaaa
     3961 aatggcaagt ccattttttg gccaacctag cgttagcgaa agtttggggg cgcccttttc
     4021 aaagggagcg gttttatttt tgcatgacta agaatgagtg ggaaaaactt aaccgcattt
     4081 ctaacaggcg gttaaagtat caaagtttga cccttccctt aaaaatgcag tggtcaattg
     4141 accgaatttt atgcagaagt gggtttttga gttttggggt ttgaaacgag aaaaaagagg
     4201 tcgatttcga cctctttttt tgatgtttct tcttatcttg atactatagg caactatttc
     4261 tgcgaagaaa tcggggctat agtatgggtc tatcccttgt ggctctaagg aagaac
//
LOCUS       DAFEIE010000117         4157 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFEIE010000117
VERSION     DAFEIE010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.124"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            179..775
                     /locus_tag="LP345_002722"
     CDS             179..775
                     /locus_tag="LP345_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL1761461.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="LP345_002723"
     CDS             899..2698
                     /locus_tag="LP345_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL1761462.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="LP345_002724"
     CDS             complement(2976..3188)
                     /locus_tag="LP345_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761463.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="LP345_002725"
     CDS             3650..3799
                     /locus_tag="LP345_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761464.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="LP345_002726"
     CDS             complement(4052..>4157)
                     /locus_tag="LP345_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1761465.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          706 c          729 g         1494 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagtaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DAFEIE010000118         4112 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFEIE010000118
VERSION     DAFEIE010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.125"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(39..281)
                     /locus_tag="LP345_002727"
     CDS             complement(39..281)
                     /locus_tag="LP345_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1761466.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(313..870)
                     /locus_tag="LP345_002728"
     CDS             complement(313..870)
                     /locus_tag="LP345_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1761467.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(883..1071)
                     /locus_tag="LP345_002729"
     CDS             complement(883..1071)
                     /locus_tag="LP345_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL1761468.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="LP345_002730"
     CDS             complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="LP345_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL1761469.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            2067..2240
                     /locus_tag="LP345_002731"
     CDS             2067..2240
                     /locus_tag="LP345_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761470.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2880..3353
                     /locus_tag="LP345_002732"
     CDS             2880..3353
                     /locus_tag="LP345_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBL1761471.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            3362..3589
                     /locus_tag="LP345_002733"
     CDS             3362..3589
                     /locus_tag="LP345_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1761472.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         1234 a          740 c          617 g         1521 t
ORIGIN      
        1 ttgttcttca tttcaacata agtttttctt caatttgctt ataatttacg tgcaaagaat
       61 gaaacgacta atactaaaat gattgcaccg atcaatgatg gaatgatagc cattcctgca
      121 attgttggtc cccaagttcc tagtaaagct tgtccaattg ctgaacctac taaaccagca
      181 atgatgtttg cgatgatccc cattgatgat cctttattcg tgattgctcc tgcaattgct
      241 ccaatgatac cgccgacgat taatgcccaa ataaatccca ttttaaattc ctcctaactg
      301 acttcttact tcttattgta cacgtggttc gttattttct ttgacttttt gtgcaccttt
      361 gcctacagca gattttgctt tatctgtttg gcgtgaagca aattgtcctg tggattttgc
      421 tgcttctgtt actttgtctt gtactgtttc ttgatctttt tggtattctt cttgtgtttt
      481 gatgtctgca acattcacat tcacttcgat aacatctaaa tgtgtcatat tgtttacttc
      541 agtactgatc aattctttga tttggttgta aatatcttcg atgtctttac cgtattctac
      601 gatcacatct agatccacag ctacttgttt cttacctact tctgtattga tacctgctgt
      661 tacgttatct gtgttgacta atttttcagc catatttgag aaaaatccgc catctaatgt
      721 caatagacca tctacatctt tcaatgcata accgatgatt ttttggatga ctttgtcttc
      781 ataagtcaat tcaccattca tcatgcggtt ttctcctttt tcatttgcca aaactgatcc
      841 atttgttgta ttcatgtttt tgttttccat ctttgtttcc tcctatgatt taaaaaattg
      901 atcaactatt cctgactgtt tcaaataaaa accgattcct gcgccaattg ctgtcatgat
      961 tatgatcaac aatgtcttga aaaatccaat cgttaaccat aaaacagcta gcagtagtcc
     1021 aagaccccca aagataatag ggagcttgta tgctgaaaat agttctttca ttatttggcc
     1081 ctcctattcc actcgagagt gcttgtagtc tcttgtatct tcttgttctt cataaccgct
     1141 gtatgtgact gccactttga ccgtttcttt tgttccgagt actttagtta cttcttcttc
     1201 gatatcttgc atcaatacac ctgttttccc tactaatgaa gaagttcgtt tcaagtctcc
     1261 gttgacatgg atatggattc gatttttcgt tgaacgtatc cgtactttag gtgaatgaat
     1321 gaactcttct tcgtgtaaat gggaacgtac caacccttcg atcgcttttt tgtcgattgt
     1381 tagtttgcca tcttcccgtt tcataacgaa agttcctctt gactttggat agaaaagaac
     1441 gactagcaag atgataatag caagaacggc aaatactaca gctgcccaga aaatatattg
     1501 ttgcatgtag taattcgtta aagtaaagaa gcgaaatcgt tccaattgtt caggcataat
     1561 atacggcgca ttgatcaacg caatcgctag aaatactgaa agtagcagta aactcatgat
     1621 aacaccgatt atttttaacc ccttattcat tttccacctc ctataaactt atttttaccc
     1681 tgtaaataac tctaccgaca atcacagtat agatagcgaa cagttagcat agcatcagta
     1741 aataaagcgc taccaaacat tgctggatca taacggcgtt ttattgccag tctgatactg
     1801 aaataacaat tgcttactta ttctctattt acttttgatt gctggctata cttaaaggat
     1861 attattcaag attaaaaatt gcaaagatta tgctcagtta ttattacaag attctattta
     1921 tttattaaat tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc
     1981 gttcttactt tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc
     2041 ttataaataa aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa
     2101 cgattggcta tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat
     2161 tcagttggac tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac
     2221 aaaattatcg aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta
     2281 tggtactttt tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac
     2341 ttttgattta taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga
     2401 tagtaccacc ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata
     2461 aaggacaaat aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa
     2521 taaacatgaa cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct
     2581 catacagttc tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta
     2641 ttgtccaata taatcccagg catctaaact agcattatag aagagacaca catagaatct
     2701 aaaataactg gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac
     2761 cttcatactc tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag
     2821 ttgttttaca ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa
     2881 tgaaatttaa aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt
     2941 tgttcggcgt acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt
     3001 ggcagaccac attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg
     3061 cttatttctt attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa
     3121 gcttaaacat actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg
     3181 gcttacttcc taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg
     3241 taggaatcgc tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa
     3301 aactgcttga acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga
     3361 catggcaatt atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga
     3421 attgagtgag aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc
     3481 aaaagccatc cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg
     3541 tgatttgttg acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga
     3601 acaaacagta aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt
     3661 acgtctatta ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat
     3721 gtactgactc atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca
     3781 actggtttcc tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca
     3841 ccagactgat agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt
     3901 tcataccttg aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat
     3961 tcttttttag taagctccca tatatactgt aaagccttct atatattatg tcatgttgct
     4021 ttttaacatt tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct
     4081 tttttatttt taacattatt ttgataataa tg
//
LOCUS       DAFEIE010000119         3855 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFEIE010000119
VERSION     DAFEIE010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.126"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..1308
                     /locus_tag="LP345_002734"
     CDS             <1..1308
                     /locus_tag="LP345_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL1761473.1"
                     /translation="SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGT
                     KGGPRMADAIRRGTLNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMAD
                     VGEAVQVSLLPFFEKATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSL
                     MGSVTKIVGEVKSFIGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHD
                     GVNSFFKGVSDVAVEIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFT
                     GNWSKAWQGLVDIFGGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGK
                     SFSISKLPYLAQGGHLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSG
                     GSIEQHIHIGKVDANNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            1320..2024
                     /locus_tag="LP345_002735"
     CDS             1320..2024
                     /locus_tag="LP345_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1761474.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            2021..>3855
                     /locus_tag="LP345_002736"
     CDS             2021..>3855
                     /locus_tag="LP345_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1761475.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT         1284 a          591 c          886 g         1094 t
ORIGIN      
        1 tctaaagcaa cagtggctta tgcgaaagac ggaaaatctt taagtcaagg actagaagaa
       61 ctacaagaca aggtaaaaaa tgcaggttct gaaacagaag ccatcaatgc agcagcagaa
      121 gtattcggga ctaaaggcgg tcctagaatg gccgatgcaa ttcgtagagg tactttgaac
      181 ctggaagatt tagcaaaaac tgctggagaa agtgggggag ctgtaggaga cacattcgat
      241 gctactctcg acccaattga tcaagccgat caagctatga acaatgcaaa attagcaatg
      301 gctgacgtag gtgaagcagt ccaagtaagc cttttgcctt tttttgaaaa agcaacttcc
      361 ttattacagg aattctctaa atggtggggg tctctagatc aagatacaaa gaattggatc
      421 ataacaattg ctggtatagc ggcagcagtt ggaccagtac taatcgttct tggttcactt
      481 atgggatctg ttacaaaaat cgttggggaa gttaaaagtt ttataggagt ttggcaagga
      541 cttgctggtt tatttggaat gtcgggaggc tggtttgcat tagcagttat agctattggc
      601 gcattagtta ctggactaat ttgggcatat aataacgtta aatggtttca tgatggagtg
      661 aattctttct tcaaaggtgt ttcagatgta gctgttgaaa tatttaattt tttaagtggt
      721 tattttggtg gatttttcga tggtgttata gcaaatttca ataattttta taatgctgga
      781 aaacgaattt tcagtggttt tctagatttt atcactggag tatttacagg gaattggtca
      841 aaagcatggc aaggtctagt tgatattttt ggaggtattt tcgatggtat tgttgctgta
      901 gggaaagctc ctattaatgc catgattgga ttgatcaatg gatttattgg tggattgaat
      961 aatataaaga taccaaaatg ggttcctggt gtaggtggaa aatcattttc tatttcaaaa
     1021 ctgccttatt tagcacaagg cggtcatcta atcaatggac aagcgattgt tggtgaagct
     1081 ggacctgagt tactgactgc caagaatggt aaaaccacag ttactccatt atcagacgaa
     1141 gaaaaacgca aagggatcag tggaagagtt tctggaggta gcattgaaca gcatatacac
     1201 attggcaaag tcgatgcaaa caatccatct gagttagatc gtatgaatcg taaatttgct
     1261 aaagcaaaca aacaggctat tcgtgatttg ggaggtgttc ctatttgagt cgacaattta
     1321 tgaatccaga tgaaccaaat tttatttgga aaaatcggaa tgcagtaatt gatatgaatt
     1381 gcatcattga ggcagagctt ccagatatta tgccgaacaa gcgatacgaa acttacacga
     1441 ttcagggccg aagcggagaa ttgacggaga cgtttgatga ctatgaacct tttgatttgg
     1501 aaatagaagg gatcactatt ccacattcga aactgagaga agtcaaacga tggctcactg
     1561 gtaaaagcca attaatcaca cataatgatc cagacaagta tctagaggct atctgcagca
     1621 tggataaaga agtccctttc gaaaacgagt ggggcttctt ttatacattc gatgttactt
     1681 ttcgttgtca gccactcaaa agaaaaatcg gtgaagcacc taaaattttt cattctagtg
     1741 ttatggatat ttttgatcat ggtgacgaaa ttgcacatcc ctatctggaa atagaatcga
     1801 acggaggaga tataacgatc gctgtcggtg ataaaagcct aacaatactt aatacgttag
     1861 ctgcaacaat cgtggttgat actcagcttg gaaaagcaat acaagaaggt ttgaatttat
     1921 ttacgcgtgg tgattggcca gtattgcagc ctgaatggaa tcaggtaaaa atatccggaa
     1981 aatttaaaga agtgcggttt tggaatagga gtgtgtatct gtgacgcaag aatttattta
     2041 tgcttataaa aaaatgccag atgatttgag cgtgaacgga gcgtcgttag ttgattggga
     2101 agatttgcca gaaatcaatc gtgtgctgaa tggccaatat cgtttttatg gtaactattc
     2161 aagaagcgga cagtatcgct cttatttaaa aaaaggaaat tttataaaag cgaaggtacc
     2221 agatggatca tggcaatatt ttgaaattta taatgtcaaa aagaatttga cctccgtttc
     2281 tgtaacagct cggcatattg gttttatggc caataagaac tttattgtca agtcgtttac
     2341 ggataacggc aatgggtctc agatcatgac caatcttaaa aacagtttgg catttgatca
     2401 aaaatttaac tatctttcga atgtagggac aacgcaccaa tttacagcaa gacaagtcgc
     2461 gccagttgaa gcaatcattg gttcaaataa cggtaatcaa aatttgactg gcgtgactag
     2521 cgcggaactt gatatggata actatgattt gaaactggta aaacagattg gatcagataa
     2581 tggttttcgg attgattttg gcatcaattt agaagcaatc gaagaagaaa ttgatgaaga
     2641 atcaattgtc aatagtttgt atttggttgg cggtgttcct gataacgatt atgatgaaga
     2701 caaagaacct atcgaatatg gttatttaga aattgatgga gtaaccaacg agaatcgacg
     2761 tattgccaaa cgtgaaaacg gagattgtaa aacagttgat gaattgatca aatggggcaa
     2821 aaccttattt gacaatgatc gtatccatga gccaaaagct actcatacag tcagtatggt
     2881 ggcgttggaa cacacactcg aatacggtga catgtatcaa gagctagcgt ctttacactt
     2941 tggtgatgtc gctcatgtta gggcgaaaga gctagatatc gagataaaag agcgtatggt
     3001 cgaatacact tatttcccaa cgcttgggaa atataaggat attgttttag gtaatgattt
     3061 atcactgtac acttcggcag taaatactca agcacaagaa ttgaaaaaga aaatcgacaa
     3121 tcgaacagaa acgttagttc aaaatgtgtt gaatgcgacg gcatggatca ctggtaattc
     3181 tggtgggcat gtcgtttttc gtccagaaaa agctccatca gagattctta tcatggatac
     3241 tccaaatgtg gcgaatgcaa agcgagtgtg gcgttggaat ttaaatggct taggttattc
     3301 agacaacgga gtaaatggcc cgttcggtat tgctatcaca tcaaaaggag aaattgttgc
     3361 tgacttcatc aaagtaggaa caataaatgc agaagtattc gaaacttcct ttaatgctta
     3421 tggtgatgtg ttaaaacttg taaaaggcac gcttcaaatt tggaatgaaa acaaaaaaat
     3481 catggagcta accaaaaaag gtatggaatt ctggaataga aaagaatcca ttggaacgat
     3541 cggaacaaca gattcagcag gaaatccatt tccaaatgct gtaacaccta cacctcttga
     3601 ggaaaattct ttggtaatac gtacaaatgg cgatggaaaa tacattttaa tttctccaac
     3661 tgcagaaaaa ggatttgtgt tattaggaaa cggaaaagca tattatttcg gtgatttaga
     3721 tattcaggga aaacttactg ttagaggtaa agaagtgata ccaggacaaa atggcggtcc
     3781 atctggcgga ggagaaacac ctggtgggta tcctgatgaa ttaaaaacag atgcagaaaa
     3841 gagagcttgg agaat
//
LOCUS       DAFEIE010000120         3833 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFEIE010000120
VERSION     DAFEIE010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.127"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..292
                     /locus_tag="LP345_002737"
     CDS             <1..292
                     /locus_tag="LP345_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL1761476.1"
                     /translation="QAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYFGDFSAFKIQE
                     VIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITKPVGG"
     gene            294..575
                     /locus_tag="LP345_002738"
     CDS             294..575
                     /locus_tag="LP345_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL1761477.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            553..879
                     /locus_tag="LP345_002739"
     CDS             553..879
                     /locus_tag="LP345_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL1761478.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            869..1207
                     /locus_tag="LP345_002740"
     CDS             869..1207
                     /locus_tag="LP345_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761479.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            1197..1562
                     /locus_tag="LP345_002741"
     CDS             1197..1562
                     /locus_tag="LP345_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL1761480.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            1569..2195
                     /locus_tag="LP345_002742"
     CDS             1569..2195
                     /locus_tag="LP345_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1761481.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            2195..2659
                     /locus_tag="LP345_002743"
     CDS             2195..2659
                     /locus_tag="LP345_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761482.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            2854..>3833
                     /locus_tag="LP345_002744"
     CDS             2854..>3833
                     /locus_tag="LP345_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL1761483.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDS"
BASE COUNT         1358 a          624 c          806 g         1045 t
ORIGIN      
        1 acaagcagaa ggtggaattg gttaccaatt agttggctat cctgtggatt ggacagatgc
       61 agcagataaa aagggtgaac cagacacgcc agttttatat tttggcgatt tttctgcatt
      121 taaaattcaa gaagttattg gtgccttgga aattcaaaaa cttgttgaaa aattctctgg
      181 taaaaatcaa attggattcc aaatttacaa cttgctagat ggtcaattgg tttattctcc
      241 atttgaaccg gcagtatatc gctacgaaat tacaaaacca gttggtggtt aagatggaag
      301 agcaaactaa agaattgtct ttagaggaaa aattcaaatc acatattcat tttgaagagg
      361 gcatggatga ttctttgctc tctttttatt taaatatggc aaaagattat gtcaaaacag
      421 caactggtgg ccaacaagaa tatcttattt tgatggttgc cggcattgcc tatgaatata
      481 gagtttcaga ggatgaactc gacaaagcta tgaatgccat gacgccattt atcgtgcaag
      541 gagcgattca aaatgccgaa gagacagacc aataatctca gatggaaagc cgaattgcta
      601 gacatcaaaa caggaacaga cggaaacgat cgtccaacta caatttacga atttaagcgt
      661 ctaatattct atgaagaact cggtgtgact tctcaagaaa aatatttatc acagcaagcc
      721 aagacagacg ttgtcagacg aattaaagtc agatgggata aatccatcac agagaaatta
      781 agtgcgctca aaattgattc tgtaacgtat aacattactc gcatttatac gaatcccgat
      841 gcaagagaaa tggagttgag tttagcttat gtcgattagc tttgatgaat tgaaaacagc
      901 gctgaaatca acaaagttag cagtgttcag agacaaagcc agattaggga cgatgtatcc
      961 atacattgtg tactcaaatg tgagtaacag caaaaaaatg gcatccggta aagtctataa
     1021 aaaattacct tattaccaag tctctttttt tacacttgga acagaacagg atttagttgt
     1081 tattgaacaa gcgctgcaaa atgctggcat tccatattca gattttacag gtatacaagg
     1141 tgatgagaac gacgataccg taaccaacta ttacacatat gtgaggtgtg tggaaaatgc
     1201 caagtaataa gaatggtttt tctgaaatat cggattattt aggaaacctt tcaaaagttg
     1261 atccgaaaaa attatcgttg gaatctttag aagaagcagc taacttttat ctaaagcagt
     1321 tgcttcctaa tattcctaag tcgctcttaa aaaagaaaca tatgcgcgat caaataaaag
     1381 tagtagttga aaacgatcaa gtgaaagttc aatttgaaga gacggccttt tactggcgct
     1441 ttgccgaaaa tggcacaaca aatcaacgtg cccaacattt tgcaagtggt acgtatgaac
     1501 aaaacaaaga aaaaattgaa gaaattatga ctagaaaaat acttgattta tgggaagggt
     1561 gattttaatt gggaaaacaa gatacttttt attttgaagg attggacgac attttaattg
     1621 cgatgatggc aacgccagat tctgttggaa ctgcaccgac ttatagtgaa gttttacgat
     1681 tgccaattgc cacaaaaatc ggtgtcaaag ggaatggaac agcattagaa aaatgggcat
     1741 ccagcaaaat gtttcgtcgt gtgtcgcgag aaacaaaaca tgaacttgcg ttggatcacg
     1801 tgggtattcc gatagaagtg atggatgaaa tcaaaggatt agttgctaaa agcggagtaa
     1861 cgtttagcaa aaataccgca cgagaatttc cgtacttcgc ctttggattt attggaaata
     1921 ttgaaaatgg cggtaaaaaa gcagtttggt atcctaatac acaactatcc aatgtgattg
     1981 acgaagagta tgccactgca gaggaagaaa caaaaattga cgatgtaact gcaaatctgg
     2041 tttccatcgg actgaaatac aataatgtga tgtatgcaag ttttgattca aatagagacg
     2101 gagcttctct agaattattt aataaattca ttgctcaacc tgtatacgat gaagaacagt
     2161 ggaaaacatt ggctaaagtt ggaggtgcgg gttaatggct cggttatctg attatggaat
     2221 tcacgttgaa gacttaaaaa attctgctgt tgtaattatt caaggcgcag aattccctat
     2281 ttcatttact atgcaaacga tggaatttat agcagatgtg tatggtggag attattcgca
     2341 atttgaatct gatatgaacg ccatgctatc taaaaaagaa ggacaaattt cttctgctaa
     2401 cttatcgcct agtgatctaa aaatcatgcg tgccttgatt tatgccatgc tgcgtactgg
     2461 tggtttagag gaagatccag aaactatttt caaatttttg ggaatgagtg gagaggtgtt
     2521 gtctgcttat agtacctgta tggaaatttt tgctagccag acatttcagg tggaagacct
     2581 aaaaaaatcc aagaagccac aagactttca aaaagcgcaa gcaaaaagaa agaaaaacaa
     2641 aaagaatcgg aagagatagg aactccttgg agtttttata tttacgttgc tctcactcta
     2701 ttgaattgga gtgagagttt ctttttaaag tctacaccta acttgtggct caaatcttat
     2761 ttacagtggt tacaacaaaa caccgatttt gaaccacctc aatctgtaac tatggataaa
     2821 tcgccttggt ggtagaaagg agcgctaaga taaatggctg gtaaagaatc tgatgtcgtt
     2881 cttaatttta aaacgaatgg cgaagtcagt tattcgaaaa caatcaaaga aatcaacaaa
     2941 gaaatgaact tagccgctgc cgagtacaaa aaccaagtgt ctgcgatgga caaggatgca
     3001 actcaaacag aaaaattgcg agcggctaaa caaaaattag aaaaacaatt aggattggct
     3061 gaacaacgat ctcaaatgct gagagaggaa tatgaaaaat ctgtcaaaga aaccggtgaa
     3121 tattctgctg aatcagaaaa actttataaa caattactca attctgaaac cggagaaaat
     3181 aaacttcgta cagcattaga acagacgaac gatgcactta aagaacaagg tgacgtttct
     3241 gttgatacag caaaaaaact ccagaaaatc gaagaaacag gtgagaaagt aaaaggcgtt
     3301 ggtgaaaaaa tgtctgttgg agtaaccgcg cctattgtag cggcaggagc agcaggactt
     3361 gcagcatttg gtgaagttga cgaggcactt gataccatca ttacaaaaac cggagcaaca
     3421 ggtgatcaag ctgatagact ttcacagtct ttcaaaaacg ttggttcaaa tactcattta
     3481 cctttacaaa cggttgggga agctattggt gaggtaaata cacaatttgg attcatggat
     3541 aaaaaactgg aagattcaac caattatctc ctacagtacg ctgaaatcaa tgatacagat
     3601 gtttcgcaat cagcaatatc tgctcgacaa gctattgatg cttatggact agaatatgat
     3661 gatttgaatt ctgtccttga tgtaacaacg aaaacatcgc agaatactgg tcaatctgta
     3721 gacgacttga tgcaaaaagc aattgatggc gcaccacaaa ttaaacaatt agggttgagc
     3781 tttggtgaag gggtcacttt acttggacaa tttgagcaat ctggtgttga ttc
//
LOCUS       DAFEIE010000121         3829 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFEIE010000121
VERSION     DAFEIE010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.128"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..292
                     /locus_tag="LP345_002745"
     CDS             <1..292
                     /locus_tag="LP345_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL1761484.1"
                     /translation="QAEGGIGYQLVGYPVDWTDAADKKGEPDTPILYFGDFSAFKIQE
                     VIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITKPVGD"
     gene            294..572
                     /locus_tag="LP345_002746"
     CDS             294..572
                     /locus_tag="LP345_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL1761485.1"
                     /translation="MEDQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            553..879
                     /locus_tag="LP345_002747"
     CDS             553..879
                     /locus_tag="LP345_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL1761486.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRPIFYEELG
                     VTSQEKYLSQQAKTDVVRRIRVRWDKSITEKFSALKIDSMTYNITRIFTNPDTREMEL
                     SLAYVD"
     gene            869..1207
                     /locus_tag="LP345_002748"
     CDS             869..1207
                     /locus_tag="LP345_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761487.1"
                     /translation="MSISFDVLKTVLKSTKLPVFRDKAAKATDFPYIVYSNVSKSKKM
                     ASSKVHRRLLYYQVSLYTTETEKDLSILELALEKAGIPYADFVGIQGDENDDTVTNYY
                     TYVRCVENAQ"
     gene            1197..1562
                     /locus_tag="LP345_002749"
     CDS             1197..1562
                     /locus_tag="LP345_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL1761488.1"
                     /translation="MPNNVNGFADIADYLGNLSKVDPKKISIESLEEAANFYMKQLLP
                     KIPKSLLKKKHMKDHVKVVVENDRVKVQFEDTAFYWRFAENGTTKQRAQHFASGTYEQ
                     NKQQIEEIMTKKIIKMWEG"
     gene            1568..2194
                     /locus_tag="LP345_002750"
     CDS             1568..2194
                     /locus_tag="LP345_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1761489.1"
                     /translation="MGKQDIFYFEGLDDILISMMATPDNVGEAPTYSEIVRLPIATKL
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIAVMDELKGLIAESGVTFGKN
                     TASEFPYFAFGFIGNIENGGKKAVWYPKTQLSNVIDEEYATADDETKIDDVTANFISS
                     GLKYNNVMYSSFDSNRDGASLELFNKFIAQPVYDDEQWKTLAKVGGAG"
     gene            2194..2658
                     /locus_tag="LP345_002751"
     CDS             2194..2658
                     /locus_tag="LP345_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761490.1"
                     /translation="MARLSDYGIHVEDLKNSATVTIQGVEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLYKKEGKISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            2850..>3829
                     /locus_tag="LP345_002752"
     CDS             2850..>3829
                     /locus_tag="LP345_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL1761491.1"
                     /translation="MSGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAATEYKNQVSA
                     MGKNATQTEKLTATKKKLEKQLSLAEKRTQMLREEYEKSVKETGEYSDQSQKLYKRLL
                     ESETGENKLRSALEQTNDSLKEQGNVSVDTAKKLQKIEEAGEKVKGVGEKISIGVTAP
                     IVAAGAAGLAAFSEVDEALDTIITKTGATGDQADRLSQSFENVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAIFARQAIEAYDMSYDDLNSVLD
                     VTTKTAQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGITLMGQFEQAGVDS"
BASE COUNT         1368 a          585 c          800 g         1076 t
ORIGIN      
        1 acaagcagaa ggtggaatag gttaccaatt agttggctat cctgtggatt ggacagatgc
       61 agcagataaa aaaggcgaac cagatacgcc aatcttatat tttggtgatt tttctgcgtt
      121 caaaattcaa gaagttattg gtgccttgga aattcaaaaa cttgttgaaa aattctctgg
      181 taaaaatcaa attggatttc aaatttacaa cttgctagat ggccaattgg tttattctcc
      241 atttgaacca gcggtatatc gctacgaaat tacaaaacca gttggtgatt aagatggagg
      301 atcaaactaa agaattgtct ttagaggaaa aattcaaatc acatattcat tttgaagagg
      361 gcatggatga ttctttgctc tctttttatt taaatatggc aaaagattat gtcaaaacag
      421 caactggtgg ccaacaagaa tatcttattt tgatggttgc cggcattgcc tatgaatata
      481 gagtttcaga ggatgaactc gacaaagcta tgaatgctat gacgccattt atcgtgcaag
      541 gagcgattca aaatgccgaa gagacagact aataatctca gatggaaagc cgaattgcta
      601 gacatcaaaa caggaacaga cggaaacgat cgtccaacta caatttacga atttaagcgc
      661 ccaatattct atgaagaact cggtgtgact tctcaagaaa aatatttgtc acagcaagcc
      721 aagacggacg ttgtcaggcg aattagagta agatgggata aatctatcac agaaaaattc
      781 agtgcgctta aaatcgattc tatgacgtat aacattactc ggatttttac aaatccagat
      841 acaagagaaa tggagttgag tttagcttat gtcgattagc tttgatgtat tgaaaacggt
      901 gttgaaatca acgaagttac cagtgttcag agacaaagca gctaaagcga cggattttcc
      961 atatatcgtt tattcaaatg tgagcaaaag taaaaaaatg gcatcttcaa aagttcatcg
     1021 acgattgctg tattatcaag tttcactcta tacaacagaa acagaaaaag atttgtcaat
     1081 tttggaatta gcacttgaaa aagctggtat cccttacgct gattttgtag gtatacaggg
     1141 tgatgaaaac gacgataccg tgaccaacta ttacacatat gtgaggtgtg tggaaaatgc
     1201 ccaataatgt gaacggattt gctgatatag cagattactt gggaaatctt tcgaaggtag
     1261 atccgaaaaa gatttcgata gaatctttag aagaagctgc taatttttac atgaagcaac
     1321 tattgcctaa gatacctaag tcattattaa agaagaaaca tatgaaagat catgtaaaag
     1381 ttgtagtaga gaatgatcga gtaaaagtcc aatttgaaga tacagccttt tattggcgtt
     1441 ttgccgaaaa tgggacaaca aagcaacgtg cccaacattt tgcaagtgga acatatgagc
     1501 aaaataagca acagattgaa gagattatga caaagaaaat tattaaaatg tgggaaggat
     1561 gatccaagtg ggaaagcaag acattttcta ttttgaagga ttagacgata tattaattag
     1621 tatgatggca actcctgata atgttggaga agcgccaact tatagtgaga ttgttcgttt
     1681 gccaattgct acaaaattag gggtaaaggg aaatggaaca gcccttgaaa aatgggcatc
     1741 tagtaaaatg tttcggcgtg taagtcgaga aacaaaacat gagttagctc tggatcatgt
     1801 aggaattcca attgctgtta tggacgaatt gaaagggttg attgctgaga gtggcgtaac
     1861 ctttggtaaa aataccgcta gtgaatttcc ttattttgca tttggtttta ttggaaatat
     1921 tgaaaacggt ggaaaaaaag ctgtttggta tcctaaaaca cagttgtcca atgttattga
     1981 tgaagaatat gctactgctg atgatgaaac gaaaattgat gatgtaactg cgaacttcat
     2041 ttcatctgga ttgaagtata acaacgtaat gtattcaagt tttgattcaa atagagacgg
     2101 agcttctcta gaattattta ataaattcat tgctcaacct gtatacgatg atgaacagtg
     2161 gaaaacattg gctaaagttg gaggtgcagg ttaatggctc ggttatctga ttatggaatt
     2221 cacgttgaag acttaaaaaa ttctgctact gtcactattc aaggtgtaga attccctatc
     2281 tcatttacta tgcaaacaat ggaatttata gcagatgtat atggtggaga ttattcgcaa
     2341 ttcgaatctg atatgaatgc catgctatac aaaaaagaag gaaaaatttc ttctgctaac
     2401 ttatcgccta gtgacttaaa aatcatgcgt gccttgattt atgcaatgtt gcgcactggt
     2461 ggtttagaag aagatccaga aactattttt aaattcttag gaatgagtgg agaggtgttg
     2521 tctgcttata gtacctgtat ggaaattttt gctagtcaga catttcaggt agaagaccta
     2581 aaaaaatcca agaagccaca agactttcaa aaagcgcaag caaaaagaaa gaaaaacaaa
     2641 aagaatcgga agagatagga actccttgga gtttttatat ttatgttgct ctcactcttt
     2701 taaattggag tgagagtttc tttttgaaat ctacacctaa cttgtggctg aaatcatacc
     2761 tacagtggtt acaacaaaat actgagtttg agccacctca atccataact atggataaga
     2821 gtccgtggtg gtaggaaagg agcgctaaaa tgtcagggaa agaatcagat gttgttttaa
     2881 attttaaaac gaatggcgaa gttagctatt caaaaacaat taaagaaatc aataaagaaa
     2941 tgaacttagc agctaccgag tacaaaaacc aagtgtctgc catgggtaag aacgcaactc
     3001 aaacagagaa attaacagct actaagaaaa aattagaaaa acaactttct ttagcagaaa
     3061 agcgaaccca gatgttaagg gaagagtatg aaaaatcagt taaagaaact ggtgaatatt
     3121 cagaccaatc tcaaaaactc tataaaagac ttttggaatc tgaaacagga gaaaataaac
     3181 tgcgttctgc attagagcaa actaatgatt cattaaaaga acagggaaat gtttctgttg
     3241 ataccgcaaa aaaacttcaa aaaattgaag aagctggcga aaaagttaaa ggtgtcggtg
     3301 aaaaaatctc tattggcgta actgcaccaa ttgttgctgc aggtgctgca ggactagcag
     3361 cttttagtga agtagatgaa gctcttgata ctattattac taaaaccgga gcaacaggtg
     3421 atcaagctga tagactatcg caatccttcg aaaatgttgg ttcaaatact cacttgcctt
     3481 tgcaaacggt aggagaagcc attggtgagg taaatacgca atttggattc atggataaaa
     3541 aactggaaga ttcaaccaat tatctcctac agtacgctga aatcaatgat acagatgttt
     3601 cgcaatcggc tatttttgct cgccaagcaa ttgaggctta tgacatgtct tatgatgatt
     3661 taaattctgt attagatgtc acaacaaaga cagctcaaaa tacaggacaa tctgtagatg
     3721 atttaatgca aaaggcaatt gatggcgccc ctcaaatcaa acaattagga ttgagttttg
     3781 gagaaggtat tacgttgatg ggacaatttg agcaagctgg tgttgattc
//
LOCUS       DAFEIE010000122         3611 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFEIE010000122
VERSION     DAFEIE010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3611
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.129"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            706..1023
                     /locus_tag="LP345_002753"
     CDS             706..1023
                     /locus_tag="LP345_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL1761492.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1114..1479)
                     /locus_tag="LP345_002754"
     CDS             complement(1114..1479)
                     /locus_tag="LP345_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761493.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1687..2169
                     /locus_tag="LP345_002755"
     CDS             1687..2169
                     /locus_tag="LP345_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761494.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2366..3256
                     /locus_tag="LP345_002756"
     CDS             2366..3256
                     /locus_tag="LP345_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBL1761495.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1230 a          557 c          664 g         1160 t
ORIGIN      
        1 ttttgagtgt agcacaaatg acttttttag ttgtctagct taattttaca atcggcgact
       61 tattgctttt gcaaaattta tttacctgtt ttctggatca acgatagtgt acattatgct
      121 atccttgttt ggattttagg acgtttaaag aggcactttt ttacataact taatccatag
      181 accttttaag catgctgtga gataataata aagaagagtt taaagcgcac cccaaaccac
      241 ttccccataa gtgtattacg ctttaaactc ttttatattt gaattcacta agaagcatac
      301 catatatttg aatttactaa gaagcatacc atatttttga aaaaaagtga gaaaaaaggc
      361 ttataattag gatttagagt aattaattag atgtttattt tataggactg atactataga
      421 ttacaaatag tatcgtattt cgcaatctta aaattatctt cttactgtga ataagataat
      481 aaaatttgta tttgtccttt ttaggtaact tattttaatc tatatacctt tctggatcaa
      541 cgaaagtata ctttatatag tcataacgcc gatggtaact atgcactgta acgataatgc
      601 tgctaaaata tctttttacg aaaaacatca caaggaaaaa cttaactatg gtattatcta
      661 aacataattt tttcggtatt taatatttaa ttaggaggta atattttgct tttttatagt
      721 aattttatct taatagtagc gatattatta cttctgaata tatggatttt tgataggagt
      781 agaaattcaa gtataggttt tagaactaaa cgaagtttgt cttctaaaaa aaattgggta
      841 tactcacaaa ctatttttta tggaggaatt gttttaatta gtttactttc ttcaacactt
      901 tattctttga atattataga tgtttccacc tcaaattcaa tatctattat tggaatcatt
      961 attgctgcaa ttattacaca actgttttta gtgtttggag agaagaaaag aagtaaaaaa
     1021 tagaaaaact agtgatagtt ttggtgatat aagaaaaaca tatatgtata aaaagaagaa
     1081 agtagcttct ctttgtacat atatggtttg tttttatgga tgccgagctt ttttataaga
     1141 taaggctacc gcccataacg acccaaggat ttgtggaact aagtaaatac ctgcaagaag
     1201 caagatcagc tgggtcggtt ttaaaggatg atagaagtaa cgccattcag taaaattggc
     1261 gcaaaataaa taggaagtga cagtagatat aatattggca atgaataaag atataatacg
     1321 cctgttcctt tgaaaataat atccagcaaa aagagataaa aatatcaatg tgatgaaccc
     1381 gcttacggaa tgataacgaa aatcaagcag taaggcgaaa tgcacataag gaacaaaaga
     1441 taaaagcaac ggaaggtttt tccagcaagt ttttatcatc tttcatcacc acctaacaag
     1501 tgttattatt ttgttagttt tattgtaaat tgaatcctgc aataatcaat tactttttca
     1561 ttatttctag attaaatgaa taaactctca tgccattatc tctaaaaaaa aagtttttcc
     1621 ccctaatttt tttagataga aaattgtata gtatgatgag agaaaaagta gtttggggga
     1681 acgttaatga gaagaaaagc agtaatcgat cggctttatt tatttttttg gttttttcct
     1741 atcgttttgc taccttttac atgggtaaat gctgttgtac aaggtgcgga gatattaggc
     1801 ctgatccaag gaagcggatt tgtggtttct aggaattttc cagctttgat tgttttctat
     1861 ttagtgataa gtgtaggtct cttattacca aaatctctga tcaatcacta caattggcag
     1921 ctgctttact tttcttgctt attagtattt acatctatgt tttctttgct gcctcgcttg
     1981 attatcggcc ctaatggttt gagcgagagt ggattgaagg atttagctta ttcctccatg
     2041 tatttcttga cgatcaaacc atggttctat ttagtaattg cctcatttat tcttgcaaca
     2101 tttttttact tctggacaga aatcaggata aaaagtgaac gatctgtatc tataaaaaat
     2161 aactattgat ggtggatcat cagtaaaaaa acatatgagc tgcgtaaaat gcatgtttct
     2221 catatgcttt ttttattatt atgtaaagaa tgcgaaaaac gtttacatga tttttacata
     2281 acttaactat atttttacag caaccatacg agggatttac agtcgactga taaactttag
     2341 ttgtaaataa gaaaggagca ataaaatgaa aaaagtattg tttactctag gtatgatggg
     2401 aattctttta gccggatgcg gctcaggatc aggaaataca gatggctctg ccacacaaaa
     2461 taattcaagt gactcaaatg aacaagtaaa aatcgttgcg gtaggttcga cagcattaca
     2521 gccgttagtc gatgcagcac aagaaagctt tgtacaagaa aatccaaatt atcaaatctc
     2581 tgtacaagga ggaggaagcg gaactggttt gagccaagtc gaagctggag cagttactat
     2641 cggaaactct gatgtatttg cagaagaaag agacggagtt gatgcttcaa aattagtgga
     2701 tcataaagta gcagtggtcg ggatggcacc aatcgtcaat aaagatacag atgtcaaaga
     2761 tatcaccaaa caggaattga ttgatatctt tacaggaaaa atcactaact ggaaggaagt
     2821 tggcgggaaa gatcaaaaaa tcaacgtcgt gaaccgtgca aacggcagcg gtacccgcgc
     2881 gacattcgaa aaatggggac tggatggtgc tacccctgtg cagtcccaag aacaagattc
     2941 atcaggaaca gttcggcagc tggtaagtca aacaccagga gcaatcagct atttagcttt
     3001 ctcatatctc gatgattcca cacaagcact aagtatcgac ggtgtagaac caaaagaaga
     3061 gaatgtagca gataacagct ggggaatctg gtcatatgaa catatgtaca cgaacggaaa
     3121 accttcccct gaagtccaaa aattcttaga ctacatgatg acagaagaaa tccaagaagg
     3181 acctgtcaaa gaattgggct atttaccaat cacaatgatg gaagtagaac gtgatcacga
     3241 aggaaatatc aaataactag cagataaaca tgccacggta gtcgttacta ttaaggaaaa
     3301 atcaactatg tttccccaca tatacatttt tcctttaatt gtgaaaaata gttcctcata
     3361 ttttgccgtt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tattcgaaaa
     3421 aaagagctac gacatagaac tgtcgtaact ttttttggct cttcgtcaaa tcgtgttggt
     3481 gaagacaaat ttgaataaaa cttagtccga tatgcggcgc gttctgtgcg ccgcatattt
     3541 ttttagtttt caaagatcag accttgttgt aaatagatcc gtgcccgaaa gttataaaag
     3601 ttgcgataac c
//
LOCUS       DAFEIE010000123         3574 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFEIE010000123
VERSION     DAFEIE010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.130"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            116..976
                     /locus_tag="LP345_002757"
     CDS             116..976
                     /locus_tag="LP345_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBL1761496.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            988..1815
                     /gene="panB"
                     /locus_tag="LP345_002758"
     CDS             988..1815
                     /gene="panB"
                     /locus_tag="LP345_002758"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBL1761497.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            1830..2678
                     /locus_tag="LP345_002759"
     CDS             1830..2678
                     /locus_tag="LP345_002759"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBL1761498.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            2688..3083
                     /locus_tag="LP345_002760"
     CDS             2688..3083
                     /locus_tag="LP345_002760"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HBL1761499.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            3285..>3574
                     /locus_tag="LP345_002761"
     CDS             3285..>3574
                     /locus_tag="LP345_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL1761500.1"
                     /translation="MSRRQRRTYSKEFKQQIVNLYLAGKPRAEIIREYELTPSSFDKW
                     MKQAQSTGSFKKRDNLTPEQAELIALRKKNKQLEMENDILKQAALIFGRKDK"
BASE COUNT         1395 a          395 c          713 g         1071 t
ORIGIN      
        1 gatattatga taaattaact atggatgata tttgaaaaaa acatactgta tatttgattt
       61 aatttttatt tttaagctca tatcgtaaga atgggacttg tagtctcact tctttatgga
      121 ggtgataatt atgaacgttg gttttattgg agccggcaag gtaggttgtt cattcgggaa
      181 gtatttccag gaacataaaa tacaagtaac aggattttat agtaaaagcg aagactcgtc
      241 attagcagct tcgaatttta catctagtaa acaatattta aacttaagag aattagtaga
      301 tgaaaatgat actattttca ttacgactcc tgatggtcaa attcaggagg tatggcaaga
      361 aattaaaaat tatcaaatca aaaacaaatt aatctgccat tgcagtggtg caatatcttc
      421 agatatcttt tcaaatatac aggactatgg tgcttatggc tattctgtcc atcctatgtt
      481 ttcaatatca gataaatata attcatacaa aaaattaaaa aaatctttta taacaattga
      541 aggcgatgaa aaatatgcaa agtttttatg tgatttcttc aaaaagttag gtaatagtac
      601 tgtaattgta tctaaggaga ataaatctct ttatcatgcc gcatcagtag tatctagtaa
      661 ccttgtgcta ggacttatta atacaagcgt tacatatcta attcaatgtg gatttactga
      721 aaaaatggca attgaagctt tatatccatt aattgaattt aatattagaa atataaaaga
      781 aaaaggaatt atagaaagtt tgacagggcc agttgaacgt tgtgatattt caacaattaa
      841 aggtcactgt gaagttttat cagatgaaga cagagcttta tatatgctat tatcaaaaaa
      901 tgtattagag atagctatgt taaaaaatat taatagagat tatagtgaat tagaaaagta
      961 tttaggagag agttaggaga gaaatagatg aaaaatacag cagttacatt taaagaatct
     1021 aaattaagaa atgaaaaatt aacaatgctt acagcttatg actattcaac agcaaaaata
     1081 attgatgaag ctgggataaa tggaatatta gtaggagatt ctcttggtat ggtatgtcta
     1141 ggacatgaag atacactttc agtaacaatg gaagacatga ttcatcatac tagagcagtt
     1201 acaagaggag ctaagaacac tttagttgtt gcagatatgc catttatgtc ttatcaaact
     1261 tcagtatatg attcagtagt taatgcagga agattaataa aagaaggacg agctcaggtt
     1321 gttaaattag aaggagggat agaagtatgc gataaaatag aggctatagt aaaggcttct
     1381 atacctgtta tggcgcatat aggtttaaca cctcaatctg ttaatgcatt tggaggattt
     1441 aaggtacaag gaaaggacaa ggaagctgct aaagaattaa taagagctgc taaagctgta
     1501 gaaaaagcag gagcattcgc tgtagtgtta gaatgtgttc caactaagct tgcagagtta
     1561 atttctaaag agatatcaat acctacaatt ggtattggag caggtgcagg gtgtgatgga
     1621 caaattcttg tatatcaaga tatgttgggg atgtatagtg attttacccc taaatttgtg
     1681 aagaaatatg ctaatttatc agaagagatg aataaagcat ttacaaaata tatagaggaa
     1741 gtaaaagatg gagtttttcc aggtccagaa catgggttta aaataagtga tgatgtttta
     1801 gaaaaattat attaaaaggg tcaagaaata tggttatatt taaaacagtg aatgatgtta
     1861 gaagtcaagt aaaagagtgg aaaaaacaag gcttaaaggt aggattagtt cctactatgg
     1921 gatatttaca tgaaggtcat gaaagtttaa ttagaaaagc atcaaaagaa aatgataaag
     1981 ttgttgtaag tatctttgta aatccaactc agtttgggaa aaatgaagat ttaggtagtt
     2041 atccaagaga cttagaaaga gatatagaag tatgcacaag aggtagagca acagcaatat
     2101 ttaatcctga agttgaagag atgtattgtg acaatgcaag tacttttgtt aatataactg
     2161 gattaacaga aggtttatgt ggagctagta ggccaataca ttttagaggg gtttgcactg
     2221 ttgtaagtaa attatttaac ataataccag cagatagagc ttattttgga gaaaaggatg
     2281 cacaacagtt agctgtaatt aaaagaatgg ttagggacct taatattgat atagacgttg
     2341 tagggtgtcc aattataagg gaagaggatg gactagctaa aagttctaga aacacatact
     2401 taagtttaga ggaaagatct tcagctacta ttttaaataa atctttaact ttagctaagg
     2461 aagctttaaa taatggagag agagacagct taaaaataat tgagataata agtaaaaata
     2521 taaatactta taatttggca aagattgatt atgtagaagt tgttgattct ttatcattac
     2581 aaagagtaaa ttatattgaa aaatcagttt tagttgcaat agcagtattt ataggaaaaa
     2641 caagattaat agataatttt acatttgaat tacaataggg ggctataatg aaagttacaa
     2701 tgttaaaagg aaaaatacat agagctacag ttgaacaagc tgagttagat tatgtaggaa
     2761 gtattactgt tgatatgaat ttattagaag cagcaggaat atatgaatat gaaaaagtac
     2821 aaatagttga tgttaataat ggaaatagat ttgaaactta tacaatagct ggagagagag
     2881 gaacagggat gatttgcttg aatggagctg cagctagatg tgtatcaact ggagataaaa
     2941 taattttaat ggcatattgt gaattaaatg aaaatgaggt taaggatcat agacctaagg
     3001 ttgtttttgt cgatgataat aataaagttg aaagagtaac atcatatgaa aaacatggaa
     3061 ggttatcaga tataattctt taggttttgt aatgttattt atatatagct agactattat
     3121 tgaaatattt attgattact aattggatag atgtcaataa agtagacaca aaaagagaag
     3181 atacagactg tagacaaagt ccattttatg tgaatcggct acactagact agacagaaaa
     3241 aataaggtgt gtagaataat aaaaaacaca ctggaggatt tttcatgtca agacgtcaac
     3301 gaagaaccta ttcaaaagaa ttcaaacaac aaatcgtcaa tctctatctc gctggtaagc
     3361 ctcgcgcaga aattattcga gagtatgagc ttacgccttc ttctttcgat aaatggatga
     3421 agcaagcaca atcaacgggc tcattcaaaa aaagagacaa cttaacacca gaacaagcag
     3481 aattgatcgc actaagaaag aaaaataagc aactcgaaat ggagaatgat attttaaagc
     3541 aagcggcgct gatattcgga cgaaaagaca agta
//
LOCUS       DAFEIE010000124         3536 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFEIE010000124
VERSION     DAFEIE010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.131"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(184..741)
                     /locus_tag="LP345_002762"
     CDS             complement(184..741)
                     /locus_tag="LP345_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761501.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(920..1531)
                     /locus_tag="LP345_002763"
     CDS             complement(920..1531)
                     /locus_tag="LP345_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761502.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSARYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(1644..1901)
                     /locus_tag="LP345_002764"
     CDS             complement(1644..1901)
                     /locus_tag="LP345_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761503.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2498..2776)
                     /locus_tag="LP345_002765"
     CDS             complement(2498..2776)
                     /locus_tag="LP345_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761504.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(2810..3061)
                     /locus_tag="LP345_002766"
     CDS             complement(2810..3061)
                     /locus_tag="LP345_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761505.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1079 a          725 c          470 g         1262 t
ORIGIN      
        1 atttgccact ttgattcgta taaagctaac aactattaac tcctctcagc taatagttgc
       61 tctctttttt attcagattc atttttgctg atcacagcct agtatttcaa tggttttgaa
      121 cactaaacca aattgttcca ttacaacatt cactggctga tgaaatggat tagtagattt
      181 cgattattca aagcgatttt ctattggtgg atcgtgttcc caactaataa gacggattcc
      241 aaacctatcg tacagatctt ctaaaccact tataaatttt gcacctattt caggtgtttt
      301 attgcgtgga tattctattg ttacgccatt aaatggatac caattaggat taggctctct
      361 ttttttctgt acatctccca tagaatagtt agcactttct gggacataat atattcttcg
      421 accatcctct aattcatcta ataagatatt tcgtgatcgt ctatcacttg ctaaatgtag
      481 acgccacgtg cgataccatg ccatgctacc tgcatctgca gaaaatccat caaataatgc
      541 aacaattgta tcttctatca caatcctttc cccatctact tcatattcta atctaaaatc
      601 aaactcccct cgggtaattt ctggtcttgg tggcttagga cccaatatta ttctacttaa
      661 aaccgcattc gttcccagat gaaacacagc tataacaaca ataatgatta atattttgtt
      721 tctatttgat aaatttctca ttattcgcac atcacctcta cattctcaca tattagttcg
      781 taatactcct ttaatatcaa aatatctact ggtcgtaata atattcgcta tgaattccta
      841 ctactcgtat aagaaaggcc aaatcatcag cttttacttg ctgatgattt ggcttgtttc
      901 tatttatcgt aattgttttc taatcaccaa aattgttaac aatcggttca gatatttccc
      961 agttgattaa ggtaattccg tattgtgtca aaacttcttg cgcttctccg aaattaagta
     1021 cagttcttat gtatccactt tctcctaata taaagtctac ctctctttta aaaccttcct
     1081 cgagatttct aagggctata tgtggtttta atgacattga ttgtacattt tcccccatat
     1141 aatatcgcgc acttcctcga ctaaaataga ttcctagatc gtccccaaaa ggtagatctt
     1201 ctctaccact agctaatcta cttctccatc ttcgttctct tttcatagaa cctgcgctga
     1261 actcacaccc gttaaactca gctatgacag tatcttcaat tatgttaatc tgtccatcta
     1321 gttcgtattc aatcctaaat ggaaattctc cataggtgat ttccggttcg ggtattttag
     1381 gtgagattaa tgcaaagaaa ggaaatatta agcttggcaa catcaaaaaa actcctccta
     1441 tgatcacaat tcccgatgta atccaaaata taatttgtac aattctcatt gatccattgt
     1501 attccatttt attcccccta ttactattca tatccgccta tctatatcga tcttccaatg
     1561 cagagataat tgcttccata ccttgatttt ttactgagtt acctatgcga gatatcattc
     1621 tccactaagg tgcatcatat tgtctatcta acatgattaa ttctccaata ggtgtatact
     1681 cctccaaaaa caacatttaa tgcatctccc tcgacaacat aagctaccat gtttgctgta
     1741 tatgtgtttg agtctaattc ataagcagat aaatttactg tcgctggatt aaatataatc
     1801 gcattcgtat ttatagctac tgaatttgct gcttcagcac caccttttga atgtccgatc
     1861 attgtgattt caatagtagg atttacgtgg acagccctca ccgtttaccc tgaccattat
     1921 agaaatcgct tacttttttg aactacgcaa caaaggatac aatgctccta acttcactgt
     1981 ctccattttt gtccactaag gaatataaaa aataggcatt aattcattta attcggtcac
     2041 aacacgttac cttttaaatc attatactgt atctcataca ttattatcaa taaactatta
     2101 taaaaatgca aaaaatgctt tatcaatcta ttttgtaatt ggtcataata tcattgaaat
     2161 cataccctgt atcgattttt cctatgaatc tcgtctattt gtgattgacg aaaaagaggc
     2221 aagacagaca ctggaatggt aattttaccc actattttgc tccaactatt tgtaatcgta
     2281 cccacttttg aaataccgag atgatcattt taattgatat gctgattccc aagcaaaacc
     2341 ccaagaaatt aaatgctcta tcgcatctag cttcttgggt tttgcttata taaattccaa
     2401 catttaaatt ttttatgctg ttcggtctca gaaatgccgt ttttgcttat atcacaatat
     2461 caagatgtca aattattcgt gttgccgatg actttgatta atttttttca aattgtttat
     2521 taagactaat gctgtctttt tgcagatacc aatgttcgaa ctttttaaca ttatcatatg
     2581 atcctgcaag ttttaacttc ttaccattag atgttatcaa agttataatt aaccttgcct
     2641 ttttcccatt aggatctttt attttatgaa ttttctgcag gtaatctctc ctaatggcag
     2701 ctatttttac ctcatcagtg ctgataaacc attgatcatc cacatacata ctgcctgtta
     2761 tgttgtgttt ttccatttct tccgagaacg aaaagtttaa ggctcgttct tacttccaaa
     2821 gttgaatgag tccatggatt ggacttagtg tgagaattga gaacaacaat aagaatccat
     2881 atcctcccgc aaacatccct aaggctatac tgtctctcca tccataagta ggattagaag
     2941 agaaaagagt caccgtttgt aataatatga aaaggaataa tccagcacaa acaccaaaga
     3001 taacaactcc aaacattgaa tttttataca atgaccattt atttataggc ttttctttca
     3061 ttttacttcc ccctactgtt ctgttcacac ggaatgaatt caaagttcat aagccctcct
     3121 ctttgaacat atgaatacga cttgctaact atactttaaa aaagcttgtt ttaagcggtt
     3181 ataggcgagt tgtaatctct attcatctca ttagcaaata acttgccgaa aagtctactg
     3241 aaattaaagc agatagtgga agaattattt agccaggata gacactattt gtgaaacaca
     3301 tgtctttact tttgaaattc tatgatgaaa agccttggaa tacagtagct cttaattggt
     3361 aatacttttt ccattataaa taacctcttt tcattttata tttatcccct ctaaaaataa
     3421 tatctaatct aatattttaa acttatattt ccctcgctgt gctaatagag cattactaaa
     3481 taaatagaaa ctagaaaaaa gcattacgcc tgccagaata aaccaattat ttgtat
//
LOCUS       DAFEIE010000125         3468 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFEIE010000125
VERSION     DAFEIE010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.132"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            50..1438
                     /locus_tag="LP345_002767"
     CDS             50..1438
                     /locus_tag="LP345_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HBL1761506.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..3170
                     /locus_tag="LP345_002768"
                     /pseudo
     CDS             1776..3170
                     /locus_tag="LP345_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
     gene            complement(3225..>3468)
                     /locus_tag="LP345_002769"
     CDS             complement(3225..>3468)
                     /locus_tag="LP345_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL1761507.1"
                     /translation="EYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTI
                     KGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT         1247 a          550 c          632 g         1039 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat ggttctgttg
     3181 caaagtttta aataaagaat aaaatccctt acggtatcta tgatttaagc tgggattccc
     3241 aataatacct tgatttcagt acagaccgaa aacccgaaga gagtgccttc ttttcgggtt
     3301 ttcttatata atcctcgaat ggcttccatg cctttaatcg tggtagaggc agtgcgtaaa
     3361 cttcgataga atttattgcg tctctttact ggacgatggt cttgttcaat caaattattc
     3421 aggtatttaa tggtacgatg ttctgtccct tgataaaagc cgtattct
//
LOCUS       DAFEIE010000126         3070 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFEIE010000126
VERSION     DAFEIE010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.133"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(334..696)
                     /locus_tag="LP345_002770"
     CDS             complement(334..696)
                     /locus_tag="LP345_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761508.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="LP345_002771"
     CDS             complement(770..1150)
                     /locus_tag="LP345_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBL1761509.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1214..2407
                     /locus_tag="LP345_002772"
     CDS             1214..2407
                     /locus_tag="LP345_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1761510.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2484..3068)
                     /locus_tag="LP345_002773"
     CDS             complement(2484..3068)
                     /locus_tag="LP345_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1761511.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          958 a          587 c          504 g         1021 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat
//
LOCUS       DAFEIE010000127         2992 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFEIE010000127
VERSION     DAFEIE010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.134"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(23..1189)
                     /locus_tag="LP345_002774"
     CDS             complement(23..1189)
                     /locus_tag="LP345_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1761512.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(1201..1554)
                     /locus_tag="LP345_002775"
     CDS             complement(1201..1554)
                     /locus_tag="LP345_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL1761513.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            1682..2704
                     /locus_tag="LP345_002776"
     CDS             1682..2704
                     /locus_tag="LP345_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBL1761514.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            2723..2884
                     /locus_tag="LP345_002777"
     CDS             2723..2884
                     /locus_tag="LP345_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761515.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
BASE COUNT          972 a          610 c          550 g          860 t
ORIGIN      
        1 ttttcccatc tgtctctttt tgttattctt tctgcttttt caacggattt tcttcataaa
       61 gagaagagat tgttgtgtac cattcaaaaa catgagtaat cactacttta gctgctgcat
      121 aaacaggaat ccccaagatc acaccgatga ttccgaacaa tttcccagaa gtcagcagaa
      181 ctaataaaat cgttactgga tggattgcta actgattccc tagtactaat ggagagatca
      241 agcgtccttc tattgtctgc tctactgcaa aaacgatcag tactttgatg atcatgaatg
      301 gacctgctac aatggctaaa aagatagccg gaatcatcgc taaaaatgat cctaagtaag
      361 ggatcaggtt taaaaaaccc gcaataatcc ccaacgtgac agcatactct aaaccaatga
      421 ccgcaaaacc aatcataaac atgattgcca cagcaaaagc cacagttagt tgtcctctta
      481 tataagaaga aacttgacta ttcatttcac tcagcacatt caacgtcggt ttttgcatgc
      541 gtgtcggtaa aaatttgaca aaataaggtg ctaattgttt accgtctttc aatagataaa
      601 ataagataaa cggcatcgtc agcagagcca ctaaaatagt cgctaccgcg ccgacaaaac
      661 ttccaagact ctgaactgta ctcttagata tatcttggat catatcgcct gccgaattca
      721 tgaacttatc acctgctgtt tccaactgtt cgcgaaattg gttgaacagc gggtcccgca
      781 aaatctcggt taatttatta tcaatcgtat ctacatattg agggaagtta ctgatgaagc
      841 tcactgtttg ttcctgaatc ttagggatga tcactacgct cccccatgcg attagtgcaa
      901 caaccaaaac aaacagccca atgatactgt aaagccttgg tacttttcgc ttttcaaagt
      961 aatcaactac cggattcatc aagtaataca agattcctgc taaaatgata ggcagaccta
     1021 cgattgctaa aaattgccag attggtgcaa acaaatatga aacttttgta aataaaaaga
     1081 cgatcagcaa tattaacaat acaacaagta aggctgtgac tacttgatta tttaaaaacc
     1141 agcgccaaaa ccacgatacc ggtctgttct tcttattttt tccttccata attcctcctg
     1201 ttagttataa aaaatttggc ttcccaaacc aatagcaggc agtctatgcg gatgaagata
     1261 gattccattt gcaatttgtc cttcttctgg acaagcatca aaaatcaatg atacgtgagc
     1321 tactgtcttt aaattcccat tggccatcgg accgacataa tcgatcgtat atacctgatc
     1381 atcaaaagca attgttccgc ctgctttcaa agaaaaaggt tcgtcttttg atacttcttg
     1441 aatcaccgaa tattttcgta aggcagctgt tgctgtttta tcgaacaaaa tcagcatggg
     1501 ttcttccttg tttattgctt ctgtcccaat ttctgtaatc tttgcctgaa tcattgcact
     1561 ctctccttta attgctttca aaaacagtat aacacattct cattctttag ccgtgtggaa
     1621 taattatgtg atagaataaa aacgaaaact atttcattac aattaggagg aatcagctca
     1681 tatgatcgaa aagataattt taggaaccta tacgcgtcgc gaaagtaaag gaatctatac
     1741 gatcgacctt gatacagaaa aagaagaatt agccaacctt tcattagctg ttgaagaaaa
     1801 tagccctacc tatgtagcaa aaagtaaagc tggcaatctt tacacagtta ctagtgtgga
     1861 tggattaggt ggtgccggtg cgtacgataa ggattttcat tttttgaatg cggtaacaga
     1921 gtctggcgct cctttgtgtt atgtagcggt tgatgaagca cgtcaattac tatacggggc
     1981 gaactatcat aaaggtgaag taaatgtcta ccatatatta ggagatggcg aactgaaagc
     2041 agcagattca atattccatc aagaagcgac aggtcctcat aaaaaccaag atcatgcgca
     2101 tgtccactat acggatctga ctcctgacca acgattagtc gtatgtgatc ttggtacaga
     2161 tcgtgtgtat acttatgatg tgtccgaaaa cggcaaattg aatcttgtaa ctaccttcac
     2221 tgcagagcca ggaacaggcc ctcgccatct tgtctttcat ccaaatggac aattcgctta
     2281 tttatttggt gaattagaca gcacagtccg cgtgctttct tataataaag aaacaggtgc
     2341 ttttgaagaa ttacagaaaa tatcgacctt gccagaagaa ttcgacggtg aaaatggagg
     2401 ggcagctatc cgcatttcaa atgatggcaa gttcctttat gcttctaacc gaggacataa
     2461 ctcgattgct gtattcgcag tttttgaaga tggttcccac attcaaaaca agcaaatcat
     2521 ctcaacagaa ggggattttc cccgcgattt cgcactagat ccaagcaata attttgtcgt
     2581 gtgtgccaat cagaacaccg ataatctgac attatatcgc cgtcatcctg aaacaggatt
     2641 actggaatta ctgaaaaaag atgtctatgt accagaatgt gtctgtgttt attttgatcg
     2701 ttagtaagaa aaggagaatg aaatgaatca gcaagacgta ttagacagac tacgggaaga
     2761 actaaatatt cctttctttg atgggaaaat cgaagataaa gagtatagcg aagaggaata
     2821 tcagaaactc aaagccgatt tacagaacta ctttgaacaa tatgtacaga atgtagaaaa
     2881 ctaatcagct ttccatacta tctgaaaaga acatcaggac aagacttttc cgtctatcct
     2941 gatgttcttt tctacaaata aaaaaccgcc gagatggtta gactcgacgg aa
//
LOCUS       DAFEIE010000128         2861 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFEIE010000128
VERSION     DAFEIE010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.135"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            4..2376
                     /locus_tag="LP345_002778"
     CDS             4..2376
                     /locus_tag="LP345_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761516.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..>2861
                     /locus_tag="LP345_002779"
     CDS             2437..>2861
                     /locus_tag="LP345_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761517.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYA"
BASE COUNT         1144 a          455 c          620 g          642 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgct tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaga agatgtttga acaccagaga
      121 aagaccaacg gtcagccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gaacgtttag aaaacaaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcggc
      301 ctggatatga caatcgaaaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc agaaaaagga aaagaaaatc ttcttcctga agtacaagca
      481 attattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 gactatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgcg
      661 ccaactgatt ctttgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agaattgatc
      781 gatcaactca aaacgttgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgaa
      961 aaggaacaaa aacaaacggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taagcaagaa
     1081 gtcaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtgaaag aacttttgaa ttttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc tgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacggggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac ttcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagcg
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
     2221 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccacagat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtagaaa atcttcattt tgagacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg c
//
LOCUS       DAFEIE010000129         2825 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFEIE010000129
VERSION     DAFEIE010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.136"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            127..477
                     /locus_tag="LP345_002780"
     CDS             127..477
                     /locus_tag="LP345_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1761518.1"
                     /translation="MSRLIIQTAFYKAIIPENLDEVKLYLWEDNGEIVGFSGVSAEEL
                     VMLFLDPDFIGKRYGSQILIELIETEDIKRIDVNSQNKYAKHFYLSHGFEIESEEDLD
                     GFGKPYPITHLVKK"
     gene            891..1709
                     /locus_tag="LP345_002781"
     CDS             891..1709
                     /locus_tag="LP345_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1761519.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYEMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(1782..2141)
                     /locus_tag="LP345_002782"
     CDS             complement(1782..2141)
                     /locus_tag="LP345_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1761520.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
BASE COUNT          966 a          394 c          500 g          965 t
ORIGIN      
        1 atgaaaatat gcttctatca ttacaagctc gtttggtgta agatgggtat aagtcattta
       61 tgttcactct ccttgtatgc tttagcgggt attacaattt gagtgtaaca taaatggctt
      121 ttttatttgt ctcgcttaat tatacaaacg gcgttttata aagcaatcat tcctgagaac
      181 ttagatgagg ttaaacttta tttatgggaa gataacggag aaattgtcgg ttttagtggt
      241 gtaagtgcag aagaattagt tatgctattt cttgatccag attttattgg taagcgatat
      301 ggtagtcaaa tattaattga gctgattgaa actgaagata taaaaagaat tgatgttaat
      361 agtcaaaata aatatgcaaa acatttttat ttaagccatg gatttgaaat tgaatctgaa
      421 gaagacttag atggttttgg taaaccatac cctataacgc atttagtaaa aaaataattc
      481 atgaatggtt tattacctga ttgaacatga ataaaagtaa tatttttatt ttgatggcct
      541 atttctaggt tatgaattat ccagatcaaa tttgtgtatt acattcagta ataaggtgct
      601 tatcttagga tcaacttatg atactagctg accaaggatg taccagttat agaaaatcag
      661 ttaaagtaaa aatgataaaa atcttatgtc aacactgatt taggctgacc tgtgggttag
      721 gagaaagaca ggtcggtagc ttttaataca aaaaatggct tgtatgtatc tagatagtta
      781 actgaaatta gaaatgttct tatttttaac ggagtaagaa aaataggctg ctttaggtct
      841 gaatactttt tcaatataat gaagatatca aaggcgacag gagtgttttt atgaataaga
      901 atcctcataa tctaaagttg gtagcagtag atatggatgg aacatttgct cgtactgatt
      961 acacatacga tatcccaagg ttcaaggctg ttttatcgcg aatgaaagct gttgattgtc
     1021 aatttgttgt tgcaagtgga aatcaatact accaattgag atcgttattt ccaaattatt
     1081 atgatgaatt aagttttgtt gctgaaaatg gtgcttttgt taaagataaa acagaggtac
     1141 tattttcagc cgatatgcct agaaaagcga tcgaggtggt ccttgattta tgtaaagact
     1201 atcctgaagt aaaaaatgtg atgtgtggtc tgaatagtgc ctactgtgaa agaggaaagg
     1261 tgagtcaagc attttttgat ctaaccaata tctattacca tagattagaa tgggtagctg
     1321 attttgcaga agttcaagat aaaattttaa aatttgctcc gactatgcct gttgaaaaaa
     1381 ccgaatttta cgttgaattg ttccgtgaaa aattagccgg gctattagta cctaccagta
     1441 gtggtcatgg ttctgtagac ttgattcttt ctgagtgcca taaaactttc ggcttgaaaa
     1501 tgttagttga gcgcttgggg attaatcctg accagtgcgt tgcttttgga gatgggggca
     1561 atgacattga gatgttggag tattgtggtc tgagttatga aatggataat gcaacggaag
     1621 ctgttaagca agttgctaag catcaatgtc cttcaaatga cgaagacggt gttttagtga
     1681 cgctcgatcg attgttccct aacacgtaaa cactaggtaa ttcatcaaaa aacctcgata
     1741 taagaaatat tcgaggtttt aaaactatat ttagaacaga tttacgaagc gtctgatgag
     1801 tcaaaataga cttggacatt gctatctaaa ataccacttt cattctttaa acgaattgtt
     1861 tgatttgatg gagttacctc taatactaaa tgcccattaa taaaggtagt atcgtattca
     1921 gatgttttaa ctgttgcttc ttcgcaaggt attgttaaat catatgctgg aatataatgt
     1981 tgtgtggaaa ctaataaaaa atgatcacca atcatacagc atccctctgc tgaagaaaat
     2041 tgattagagc catcatttaa agttaacaag aatccatcct ttaaacgagg tacttgctta
     2101 aatacttctg gttgtacttc taaaaataaa ttatcgctca ttttcacgac caccatcgac
     2161 ttccacagtt gaaattgaca ttttatttaa cacacctatt cccccttaac tataactcaa
     2221 ttctatataa aaaatattct attctcaaat aattgaactt ttcaaatcgc caatttactt
     2281 cggctttatc agagctcatt catatcaaga gcgattaacg ctgtaaaaat taaaccgaag
     2341 atctgataaa ttttctctat tttctacaat atttaaaacg cttccttagt ctattatata
     2401 tctatttctc ttaggagtat gtttagatgt ttgaataata gttgcccaac tttaaaggtt
     2461 attcttataa tattttactt cattttccaa tagaaaattc aaaggattac tggtttttct
     2521 aaaatagttt agtttaaata cataagtatc ctccgacact gtattagttc ataatcatct
     2581 aaatacaaaa ttttcaaata aaaatatttc aagctctatc gttgacgaat gtaaacgata
     2641 cttataaagt aatagaaatt gattacattt gtaaacttaa aatggttaat ttatctcaca
     2701 taaaactaag aataaaataa tgattaaaag tggttagttt ttatacgatt tagcctatcg
     2761 gtaaaaatga attagagagt gtaaaatatt ttgtgtaaat gaaaaaatcc atacaaaaaa
     2821 ggaag
//
LOCUS       DAFEIE010000130         2820 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFEIE010000130
VERSION     DAFEIE010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.137"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(61..936)
                     /locus_tag="LP345_002783"
     CDS             complement(61..936)
                     /locus_tag="LP345_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1761521.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(1191..1275)
                     /locus_tag="LP345_002784"
     tRNA            complement(1191..1275)
                     /locus_tag="LP345_002784"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1239..1241),aa:Leu,seq:caa)
     gene            complement(1293..1364)
                     /locus_tag="LP345_002785"
     tRNA            complement(1293..1364)
                     /locus_tag="LP345_002785"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1330..1332),aa:Gln,seq:ttg)
     gene            complement(1374..1446)
                     /locus_tag="LP345_002786"
     tRNA            complement(1374..1446)
                     /locus_tag="LP345_002786"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1411..1413),aa:His,seq:gtg)
     gene            complement(1508..1592)
                     /locus_tag="LP345_002787"
     tRNA            complement(1508..1592)
                     /locus_tag="LP345_002787"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1556..1558),aa:Leu,seq:caa)
     gene            complement(1613..1683)
                     /locus_tag="LP345_002788"
     tRNA            complement(1613..1683)
                     /locus_tag="LP345_002788"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1649..1651),aa:Cys,seq:gca)
     gene            complement(1729..1800)
                     /locus_tag="LP345_002789"
     tRNA            complement(1729..1800)
                     /locus_tag="LP345_002789"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1766..1768),aa:Gln,seq:ttg)
     gene            complement(1812..1884)
                     /locus_tag="LP345_002790"
     tRNA            complement(1812..1884)
                     /locus_tag="LP345_002790"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1849..1851),aa:His,seq:gtg)
     gene            complement(1887..1960)
                     /locus_tag="LP345_002791"
     tRNA            complement(1887..1960)
                     /locus_tag="LP345_002791"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1926..1928),aa:Trp,seq:cca)
     gene            complement(1967..2047)
                     /locus_tag="LP345_002792"
     tRNA            complement(1967..2047)
                     /locus_tag="LP345_002792"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2011..2013),aa:Tyr,seq:gta)
     gene            complement(2049..2124)
                     /locus_tag="LP345_002793"
     tRNA            complement(2049..2124)
                     /locus_tag="LP345_002793"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2089..2091),aa:Phe,seq:gaa)
     gene            complement(2160..2232)
                     /locus_tag="LP345_002794"
     tRNA            complement(2160..2232)
                     /locus_tag="LP345_002794"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2197..2199),aa:Asp,seq:gtc)
     gene            complement(2242..2314)
                     /locus_tag="LP345_002795"
     tRNA            complement(2242..2314)
                     /locus_tag="LP345_002795"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2279..2281),aa:Val,seq:tac)
     gene            complement(2330..2401)
                     /locus_tag="LP345_002796"
     tRNA            complement(2330..2401)
                     /locus_tag="LP345_002796"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2366..2368),aa:Glu,seq:ttc)
     gene            complement(2416..2505)
                     /locus_tag="LP345_002797"
     tRNA            complement(2416..2505)
                     /locus_tag="LP345_002797"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2469..2471),aa:Ser,seq:gga)
     gene            complement(2545..2618)
                     /locus_tag="LP345_002798"
     tRNA            complement(2545..2618)
                     /locus_tag="LP345_002798"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2582..2584),aa:Asn,seq:gtt)
     gene            complement(2628..2743)
                     /gene="rrf"
                     /locus_tag="LP345_002799"
     rRNA            complement(2628..2743)
                     /gene="rrf"
                     /locus_tag="LP345_002799"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          829 a          652 c          536 g          803 t
ORIGIN      
        1 aatcatagtc catttactat gtgtcatttg gttgcgccta tagatagtta cgcccttatt
       61 ttaatagatt cttgctagat gaattgccaa atagatgatt tcattttctt gaatggcaag
      121 ttgaaattgc tgttcgatga tatctttaat ctttagtgct gtacaatacg ctttgctatg
      181 tttaaatgtt tcagtaaaaa aaccaatatt ttctactggc gtttcttcct gataaatcaa
      241 gcgtttaacc aggaatttga tatgaaccat taagcgatga taagtcagtg attctttatc
      301 ataaacgttt gaataggatt tttctagatg ggacaaaatc gtggtcgtca tttctactat
      361 ttttaagctc tttaaactat taggctctcc tagctcagca ttaatgatat gcatagtgat
      421 gaatcctact tcatttgacc ctaactcggt ttgatatcga tgattgattc gctcgaccac
      481 ttctactgct atatcatatt catttggata aaggaatctc atttctggca acataattgc
      541 tgtgacatct ctatcttctc tttttcgttg aatagcaaaa taaatatgat ctgtcaatgt
      601 aatatagata tttgaatcta atggagagga gatcctagct gttatcagtt caatcacttc
      661 ttccgcaaaa tccataaatt cgattggaat ctgcgagact atctcactga atcgtttgat
      721 cttttcttta gaatctaata caaataattt gtcagcatcc tcaacatcaa atggcttact
      781 cactttagca gaaaagccaa tccctttccc catcgcaatt ttttctattc catcgtcatc
      841 gatcaataca gcattatgat tcagcttttt catcacatac accgttaatt cacctcctct
      901 atatgataaa acaaaacaac ttgcagactc cttcatacat atttttgtct ccaaacaatt
      961 tttaaagaca aaaaacgacc taagaaagaa ccctttctta ggtcgtgcct aattgaatag
     1021 tagcacccta cataatttac aaaaatagtt taacacataa taaaagcgtt atcaatatct
     1081 tttttactcg ttttatgata atacttgtat cgaattgatt tggaggtaat tacataaaaa
     1141 caaaaaaaat atagcaactc tctataagaa agttgctata ttgataatta taccggcggc
     1201 cggggtcgaa ccggcacgtc ctcaacggac actggatttt gagtccagcg cgtctgccaa
     1261 ttccgccacg ccggcaaatt taaaaataat aactggggta gctggattcg aaccaacgca
     1321 tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaagaata aagggcgaat
     1381 gatgggaatc gaacccacga atgccggagc cacaatccgg tgcgttaacc acttcgccac
     1441 attcgccatc ataaaagatg ttatttaatt tctcaataaa aaactaagat gaagacatct
     1501 tagtcaatac cggcggccgg ggtcgaaccg gcacgccctc aacgggcact ggattttgag
     1561 tccagcgcgt ctgccaattc cgccacgccg gcaagttgat ttattagtac taaggcggta
     1621 accggatttg aaccggtgat gaaggttttg cagacctctg ccttaccact tggctatacc
     1681 gccattatac tattatcaat ctataaaata aagaataaat tatagaaact ggggtagctg
     1741 gattcgaacc aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca
     1801 agaataaaaa gggcgaatga tgggaatcga acccacgaat gccggagcca caatccggtg
     1861 cgttaaccac ttcgccacat tcgccatggc aggggcagca ggaattgaac ccacactaac
     1921 ggttttggag accgctgttc tacctttaaa ctatgcccct ataaaatgga ggagagtgga
     1981 ttcgaaccac tgaaccctaa ggaacggatt tacagtccgt cgcgtttagc cacttcgcta
     2041 ctcctccatg gtggcgcggg acagaatcga actgccgaca cacggagctt caatccgttg
     2101 ctctaccaac tgagctaccg cgccatattt taaaattatt aattgaataa caagaacgac
     2161 ggttccgacg ggaatcgaac ccgcgatctc ctgcgtgaca ggcaggcatg ttaaccccta
     2221 caccacggaa ccagttcatt atggaggtta acgggatcga accgctgacc ctctgcttgt
     2281 aaggcagatg ctctcccagc tgagctaaac ctccaacatt caattaaaat gacccgtacg
     2341 ggattcgaac ccgtgttacc gccgtgaaag ggcggtgtct taaccgcttg accaacgggc
     2401 caggtaaatt tgctacggag agtaagggat tcgaaccctt gagacagttt ggcaccatct
     2461 acatgatttc caatcatgct ccttcggcct ctcggacaac tctccagagt gaaagaagct
     2521 caatactctt tctcaaaatg agaactccgg cagtaggact cgaacctacg acatcatgat
     2581 taacagtcat gcgctactac caactgagct atgccggaat aacatcagcg tggcgacgtc
     2641 ctactctcac aaggggcaac ccctcactac aatcggcgct aagaagctta acttctgtgt
     2701 tcggcatggt tacaggtgta tccttctcgc tatcgccacc acactgtggt gttatctttt
     2761 attgagtaaa ttttgttcac tcaaaactgg atttgaagtc acataagttt ttttccgagt
//
LOCUS       DAFEIE010000131         2714 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFEIE010000131
VERSION     DAFEIE010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.138"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..929)
                     /locus_tag="LP345_002800"
     rRNA            complement(<1..929)
                     /locus_tag="LP345_002800"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(1602..1958)
                     /locus_tag="LP345_002801"
     CDS             complement(1602..1958)
                     /locus_tag="LP345_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBL1761522.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(1972..2382)
                     /gene="spx"
                     /locus_tag="LP345_002802"
     CDS             complement(1972..2382)
                     /gene="spx"
                     /locus_tag="LP345_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL1761523.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          742 a          616 c          458 g          898 t
ORIGIN      
        1 gtttcaacct tgcggtcgta ctccccaggc ggagtgctta atgcgttagc tgcagcactg
       61 aagggcggaa accctccaac acttagcact catcgtttac ggcgtggact accagggtat
      121 ctaatcctgt ttgctcccca cgctttcgag cctcagcgtc agttacagac cagagagccg
      181 ccttcgccac tggtgttcct ccatatatct acgcatttca ccgctacaca tggaattcca
      241 ctctcctctt ctgcactcaa gtctcccagt ttccaatgac cctccccggt tgagccgggg
      301 gctttcacat cagacttaag aaaccgcctg cgctcgcttt acgcccaata aatccggaca
      361 acgcttgcca cctacgtatt accgcggctg ctggcacgta gttagccgtg gctttctggt
      421 tagataccgt caagggatga acagttactc tcatccttgt tcttctctaa caacagagtt
      481 ttacgatccg aaaaccttct tcactcacgc ggcgttgctc ggtcagactt tcgtccattg
      541 ccgaagattc cctactgctg cctcccgtag gagtttgggc cgtgtctcag tcccaatgtg
      601 gccgatcacc ctctcaggtc ggctatgcat cgcggccttg gtgagccgtt acctcaccaa
      661 ctagctaatg caccgcgggt ccatccatca gcgacacccg aaagcgcctt tcaaatcaaa
      721 accatgcggt ttcgattgtt atacggtatt agcacctgtt tccaagtgtt atccccttct
      781 gatgggcagg ttacccacgt gttactcacc cgttcgccac tcctcttttt ccggtggagc
      841 aagctccggt ggaaaaagaa gcgttcgact tgcatgtatt aggcacgccg ccagcgttcg
      901 tcctgagcca ggatcaaact ctcataaaaa gttcgaacaa tcttgcgatt gttaagctca
      961 atttgtttgc tagcatattg cttgcttgtt aaaaaatgtt tgttgtcttg aattgaatca
     1021 agacgcccta cacatttggt ttgtcttact ttgttcagtt ttcaaaggtc tacttcatca
     1081 ggagtgttcc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
     1141 aagtaattgt caactctttt ttaaaagttt ttttgatttc gtttttcgaa atcttacagc
     1201 aactcattta tcataactta tcatttgtta tttgtcaagg acttttttga agtttttttc
     1261 gatagaatca agcttcacaa gtggttcttt tttaacaact cagttatctt atcatgtcat
     1321 ttctaacatg tcaacaacta ttttatatgt tttttaaaat actattttat tgctttgcta
     1381 cttaaaacaa cagaaatgaa tatatcatgt aaatttacac atgtcaatat atttttaact
     1441 ctatatcccc acctagattt gaattttgac cacataaatt gagcatgtct ctatagtaga
     1501 aaaataaagt caaaaaaaga acacataaca cgcttgatgc taagtgttcg actgttacaa
     1561 ctgtatgaaa tgctcagtga cttgattaaa acagttaaag tctatttatt taagataagc
     1621 tgttccatca actgctcatt gtatccaata aatagaactt catcgataat aatcaaagga
     1681 cgtctgagga gattggtatg ttgtgtgcat aaaaaaatca gttgtttttt tcctacacag
     1741 gaaaggtcaa tcgcaatgtt gtgaaaagcc tcagaccaag tcgcaaatag ctgttctgct
     1801 tgcacttctt caaaactgca taattcttct gcttcttctg tacttagatc gcgttcttct
     1861 aagtcaacaa attgataagg caattgatgg tgttctaacc attgtttcgc cttcagactt
     1921 gttacacagt gcgctgatcc atagactttc acttccacga aggctccctc cctatgaatt
     1981 taagatgtta ttgttttgta aatagatcag atttctggca acacatcgaa tttcacgagg
     2041 gacaaatgac cggatctcat cttcattaaa tccgattagt attctttttt catcaatcaa
     2101 aataggtcgt ctcaataatg aaggatattc tttgaataag acgatcattt gctttaaagt
     2161 taattcgtta aaatctatgc ccagcttttc gtaaattttc gaccgagtgg aaataatatc
     2221 ttgaactcct ccttcagtcg ctgccaagat ctttttgatc tcactttctg ttaacggttc
     2281 ggcaaaaata ttcttctctt caaattcaag ttgattcgct tgcaaccatg ctcttgcttt
     2341 tctacaggaa gtacagctag gcgaagtata tacttttatc attttctcac tcctttttaa
     2401 ttataatcca attctacagt aatttctttt aaaataccaa ttattagcta ataaaatata
     2461 aaaaaaatca aaataactga ttatttacgt ttgaataatg agaatttttc tatatattct
     2521 ctattttgat aatagtattc tcattttcaa aataaataag ggaggtgtga caaaattctt
     2581 gtcacacctc ccttttccga ataaactgtg ttccagaaat agcttcttcg aaaataagct
     2641 gaaatttcac aaaaatttga gaagcaattt tcgtacattc cttcttcttt cttgaaactg
     2701 accacttctg tcac
//
LOCUS       DAFEIE010000132         2634 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFEIE010000132
VERSION     DAFEIE010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.139"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            5..1150
                     /locus_tag="LP345_002803"
     CDS             5..1150
                     /locus_tag="LP345_002803"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBL1761524.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1321..1779
                     /locus_tag="LP345_002804"
     CDS             1321..1779
                     /locus_tag="LP345_002804"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBL1761525.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..2408
                     /locus_tag="LP345_002805"
     CDS             1938..2408
                     /locus_tag="LP345_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBL1761526.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="LP345_002806"
     rRNA            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="LP345_002806"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          863 a          504 c          496 g          771 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccat aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttctttaact taataaaaat aaaaaaagat gaactatttc tagttcatct ttttgccttt
     2461 gcgtggcgac gtcctactct cacaaggggc aacccctcac tacaatcggc gctaagaagc
     2521 ttaacttctg tgttcggcat ggttacaggt gtatccttct cgctatcgcc accacactgt
     2581 ggtgttatct tttattgagt aaattttgtt cactcaaaac tggatttgaa gtca
//
LOCUS       DAFEIE010000133         2468 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFEIE010000133
VERSION     DAFEIE010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.140"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(493..1785)
                     /locus_tag="LP345_002807"
     CDS             complement(493..1785)
                     /locus_tag="LP345_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1761527.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2059..2319)
                     /locus_tag="LP345_002808"
     CDS             complement(2059..2319)
                     /locus_tag="LP345_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761528.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          823 a          459 c          372 g          814 t
ORIGIN      
        1 ttatattata aattcacatg attatcgaat tttattaagt tagtttttct tgtaaatctc
       61 tgttcccaat gaaactcgag acacttattt taaagaggaa acaatgtggt atttaaatag
      121 ccctcttgta tgggctactc tgtgatactt attagccatt aaactatttt acccacatag
      181 catatatttt gaaatcgttc attccgtaaa ttcaactaaa tatgcctaaa aaaataaaaa
      241 atctaagata gaataagatt tattcagtct tagatggatt tatagcaact ttttcgtaac
      301 aactttaaaa aatacgaaaa gaaagagctg ttttactctg actacgttgc taaattgtcg
      361 tttaatcatt catttaaacc aaatcttttt ttatagaatt cgttttaatc ctcctgaatc
      421 caaaaactat gaaaaccgta attaaatagt taagagtttt taaccaccat aattctctcg
      481 gctattttga aatcagataa attttgatcg gacacatagt tgaataaacc taccgttgtt
      541 acggaaggta aatcgcatac ttttcattct agaggagaag gtctcgttga tcattaactg
      601 attaagcacc atagcccagt tttgaattcg accacctgac cacttcgcgt gtaattcttt
      661 cgtgcgtaaa taaagtagtt ttaggagtgc attctcatta gagaacgctc ctttttttgt
      721 gacttttctg aagctggagt ggacactttc aaccgcattg gtagtgtaca taatttttcg
      781 aatggcacta ccataatcaa atagttgttc aacatgtgca aagttccgtt tccagacatc
      841 tacagcacca gaataatgag accaccgatt ttgaaaactg tcaaaagcag catgtgcagc
      901 gtttagagaa gaagcaccgt agaacttttt catatctcgg cagacttcct tatagtcctt
      961 acttggaata tagcgcaatg catttcgaac aagatgaaca atacagcgct gaacaattac
     1021 cgatggaaag atcgcttttg cgccttcttc gaggccagaa acaccgtcca tcgaaatgaa
     1081 aaagacatct tcgacaccac gtgctttcag ttcatcaaat acttgcatcc agcgattttt
     1141 agattctgtt tgatttaacc ataatcctaa aatctcctta tttcctttga gatcatagcc
     1201 aagaatggtg tatacagcat attctttggc ttcataattt tctcgtaaag taacatacat
     1261 acaatcaacg aatagaaagg cataacactt tgctaggggg cgggcttgcc attcttccaa
     1321 ttcaggaagg acagcgtcag tgatatctga aatcatttca tgggaaatat caaagccata
     1381 aatagcttcg acggttgcgg caatatctcg ttgactcatt cctcgtgcat acatggaaag
     1441 aaccttccct tcgatgtcgg agacatctcg ttttctctta ggaattaact ctggttcaaa
     1501 ggaagcttcc cggtctctag gaacatcaat agctacttca ccaaaactgg ttttaagcgt
     1561 tttagttcca tagccatttc gacggttatc gtgttcctta ggctctttag aatgggcatc
     1621 ataacctaaa tgattattca attctccttg aagcattttt tcaaaaaggg gcccaaacac
     1681 atctttcaaa gcatcttgca tgtcatcgac agattcaggt tgataggcat tcagaatgga
     1741 ttcagctaac ttttcggcat caggatttct tttctttcta gccatcgtgt aatcacctct
     1801 tgatcttatt gtagaaaaag aaaaaccgcg aagcaaccac ctgcctagga ttaatggtta
     1861 cttacacggt ttatattaca ctctcatcat taaaaaagta tctttcgata ttactaaaca
     1921 atgaaattat ctatttgaaa tttaaatctg ataatatatt gagtgttcca atgagggctt
     1981 tgatcctatt atccatatct ttttcagttt taatattgat acacattata agaaaaagaa
     2041 acttttggtt aatttatttc atcccagtgc aaaatataaa aaagtaaaat agaccatagg
     2101 caatagatta acaattaata taatacaagc aaatattcta ttcattgtat ttctgctttc
     2161 aaaaagttct aatattgaaa gtataattcc acaaatgcct ataataagta tgggaataag
     2221 attagaaaat aacaccccga gccaatctgt gaaaattact atatttacta atatccctat
     2281 taacatacct atcatattta ttaaatcaat ttttttcatt agatatttct cctttattaa
     2341 atctgaagta cttatattaa aataattcta aactatttac ctcaaaaagt gcaataaatt
     2401 atttctgaac aataaaatga tagtcaaaac aaaaaaatat tgttaatcgt tcagagccat
     2461 ccgagagt
//
LOCUS       DAFEIE010000134         2398 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFEIE010000134
VERSION     DAFEIE010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.141"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            207..2069
                     /locus_tag="LP345_002809"
     CDS             207..2069
                     /locus_tag="LP345_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1761529.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="LP345_002810"
     CDS             2069..>2398
                     /locus_tag="LP345_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1761530.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAFEIE010000135         2290 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFEIE010000135
VERSION     DAFEIE010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.142"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            1174..1728
                     /locus_tag="LP345_002811"
     CDS             1174..1728
                     /locus_tag="LP345_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1761531.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            1982..>2290
                     /locus_tag="LP345_002812"
     CDS             1982..>2290
                     /locus_tag="LP345_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761532.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     L"
BASE COUNT          888 a          253 c          355 g          794 t
ORIGIN      
        1 aggaaaacgt agacgtaatt ttctacgttt tccttttcat atatattaaa tattacggaa
       61 atttatataa actaatttag tgttttgttt gtaattccta attttgctcc acttttagat
      121 aatttttagg tctatttaac tcatcagaca ttctatgctc attttctcca aatttgtttc
      181 aactctttcg tacttaattt tgcgtatttg aaaattcttc ttttagagta cttttattac
      241 gatactagta tgatatatat ctatagcaaa cagttaaaat cttcctaaaa taagcgaata
      301 gcattcctaa aacctataaa atttttagat gaagcgacaa gtggacaatt aataaactac
      361 ttgaacatga aattatggat cacctttcaa atttagaaaa tggaattctt atacttattg
      421 cgcaacattt attgattgca aaattatgtg acaaaaagaa ctagtagaag aaggaataat
      481 ggcttgataa taaagtacta cctattaaag gtagtacttt atttaattta gtataaatta
      541 acatactact atattttaag tttcatatta tataaattaa taatatacta ccattttttg
      601 gtagtataat ttaaaggtaa taagttattc ttttattact atgtttgggt tttatagcaa
      661 ggaaagttta ataagagttt ggacctagca aacaatatta atgaggtcat taaatcttat
      721 tatctttagt gatataacga aatatctaca cagacaaaat tatgatcttg cgtaaagtta
      781 taaaatatta ataaaaatat tttattaatg aaaagcttgg tagcacggtt attcatatgc
      841 taatttattt cactttatag taaggggagt tcttagtata ttgtccaaat ttaaatttca
      901 tataatttaa ttatgtaaat tagctattct aagaacttct acggataact gcccgtctaa
      961 aatttaatta agagcttaga atcttcatat aagtaaggtt aatttttttg tacaaaatag
     1021 tcggaatatt ctgagttact gaaatgatat aaaatcataa actaaacccc ttgattttct
     1081 tcacttttaa cagagtatat atataagttc atgattatgg taaaatatat atataatcat
     1141 gaactcagaa tatttttaag aagggaaaca atagtgagct ataatgtaca accgttaagg
     1201 acaaatgaag agatacaaga ttttcagttt tggctaagaa gaacaagtaa tccagaaaga
     1261 gatagttttt tatttttgtt tggaatcaat aatgggttac gtatgtcaga tattatagga
     1321 ttaaaagttg gagacatacg aggtaaaagt aagcctatta ttgttgaaca taaaacaggt
     1381 aagcgaaaac cgatttttat agataatttg agagaagaga ttttattata tactgaaggt
     1441 aaagaagaaa atgattggtt atttccaagt cggcaacaag gtcgacatat aacaagggat
     1501 cgtgtctatc agatatatgc agatatagca gaaaaattag gaagagatga tataggaaca
     1561 catacattaa gaaaaacttt tgggtatcac tactacaaga aaactagaga cattgctacc
     1621 ttaatgttta tttttaatca tagctcgcaa gcaattacaa aaaggtacat tggtataact
     1681 gaagatgaaa taggggcatc gttacgtggt tttaaattgg gaggctaatt gagatattag
     1741 gatatatttt ttgtgtataa tgaaaactta gaaggtgaga ttaatgaaga taactgaatt
     1801 ttcggaagta tttaaaacgt ttagtaacat ttacaataga ataccagaga tagaacaaaa
     1861 tgttgtagtt gataatgatt attatataga gaatgatttt aataaaccaa gaaaatatga
     1921 caacctatac aattttatac acaatagaac aacaataaat aacaacagta acactcgagt
     1981 tttgattaat tcagcatatt ttcatattaa atatttaaag aaatatgagt atgaagaagt
     2041 tgtattagat tatgggctaa atagacagtc atttttaatt tatgcaataa ataacggaaa
     2101 tttgccaagc aataaaaaga acataattat tgaaacatat gcctatctgg aggggggatc
     2161 taaaaaacta attaagtcat gtaatataga gtatcaatta tcagtaggag aaattaaatg
     2221 tgttttcgaa gaagatttag aacttgactt aaaaaaaatt tttgccagca ttcatgatta
     2281 tataggtttg
//
LOCUS       DAFEIE010000136         2255 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFEIE010000136
VERSION     DAFEIE010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.143"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..306)
                     /locus_tag="LP345_002813"
     CDS             complement(<1..306)
                     /locus_tag="LP345_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1761533.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRIGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     "
     gene            980..1792
                     /locus_tag="LP345_002814"
     CDS             980..1792
                     /locus_tag="LP345_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761534.1"
                     /translation="MILLAVSMSLLIYTHILSTFMSVIVIGFLFIGSLFSKRKERKEM
                     SNLISNMIKAVGWTILLTAYVWYPMLQQVLHQKINRPFRTKLQERALNISDSLIGAVN
                     NDLVTFTMGTIGVVSFILPLFFKKKFANKEKIINFCAVTTWFLSTNLFPWEFLQKTPI
                     QIIQFPWRILGFQVLFGSLILIIVFLKWKTSNKKSMCSLVGIVLLIFTVTVATEANYS
                     QKIQSYKGRLIMTKKDVTLYTTSRTGGLYDYAPLDALKYKDHLKKHEVKVYD"
BASE COUNT          744 a          326 c          376 g          809 t
ORIGIN      
        1 ggctttttcg tttcgttgat aacgttcaaa cactgtgggt gaaaaatggc catcacgtgt
       61 tctgggtact tttaattcta gcgtgcctat acgtgtcgta aagctgcgct cataatagcc
      121 atttcgttga ctttgtcggt tttctgttcg ttcatattct tttgcttgaa tatattctgt
      181 tcgttgattt tccattagtt gattaaatac cgttgttaaa atatttttag aaacgtcatc
      241 ctttacagaa tattcaataa tgctttgaat ctcttcgctt ttcagtgtaa aatgtacttg
      301 ggtcatgtaa aagtcctcct gggtatgttt ttgtcgttaa aaacattgta ccgtaaaagg
      361 actgttacat ggccttttta cttttacaca attataagga ctttatcgaa aaaaagcagt
      421 tatttgttaa aatcattgat attattaata ataagtattt tttgaaaggg gaaatataaa
      481 aggtttttga aaataaataa aaaatagtat tacttgttct attgctagtt attgctagtc
      541 tttattcttt tttgtttttt agggatgtac aaaagatctc aaccacagga gacattgctt
      601 ttcacttttc tagaataaaa tgcttgtcct cagtattttc tggtccaata aattttacca
      661 catttaatag ctatggcgga ggcgtgaatt tttttatcca tatctaacat ctttccagcc
      721 gtaatatttt actggacaac aaacaatttg attctaagtt atatacttac tatacgttgg
      781 gatactgaat atctgtacaa ttctagtgag ctatcaatat ggacaaaaga atagatgcag
      841 ccttcttatt cagctgtttg tatagctttt atggattgat atatattagc gtactgcaat
      901 ttcagaatca attgcgttga cgattgtacc agttgtcttg tattacacat atactcttct
      961 ttatgaaaga aaaaactgcg tgattctttt agctgtcagt atgagtttgc tcatctatac
     1021 ccatattctc tccaccttta tgagtgtgat tgttattggc ttcttgttta tcggctctct
     1081 tttctctaag cggaaagaga gaaaagaaat gtcgaatctg atatcaaata tgataaaagc
     1141 tgttggttgg accattcttt taacagctta cgtttggtat ccgatgttac aacaagtcct
     1201 acatcaaaaa attaatcgtc cttttcgcac aaaacttcaa gaaagggcat taaacatttc
     1261 tgatagttta atcggtgcag taaataatga tttagttaca tttacaatgg gaacaattgg
     1321 tgtggtttca tttattcttc cacttttctt taaaaaaaaa tttgccaata aagaaaagat
     1381 tattaatttt tgtgcagtga ccacttggtt cttatcaacg aatctttttc catgggaatt
     1441 tttacaaaaa acacctattc aaatcattca gtttccttgg agaatcttgg gttttcaagt
     1501 gctttttggt tcattgatct taattatagt gtttttaaag tggaaaacaa gcaacaaaaa
     1561 aagtatgtgt agccttgtag gaatagtcct tcttattttt acagtgactg tagcaacaga
     1621 agcgaattat tcgcagaaaa ttcaatcgta taaaggtcgt ttaattatga ccaaaaaaga
     1681 tgttacactt tatacaacct cgagaactgg aggtctttat gactatgcac cattagatgc
     1741 attgaaatat aaagatcatt taaagaaaca tgaagtaaaa gtctatgatt gatgggagaa
     1801 tgcatctcat aaagcacata attctaaaat aatctataca gtaggagatg cgaatgagca
     1861 aaatatcacg ttacctgtat ttaattactg ggaacagtta tgaaagtaaa tgggaaaaag
     1921 agcactatag aaaatgacaa tggtttagtg tctattaaag gtacgggaaa aagaactata
     1981 gttgaggttt catctacgta tccaactacg atgattctat ctttattaat tagttcaata
     2041 acttttatat tcttatttac acgttattta ataagatgct gcggttaaat gaaaatagat
     2101 tagatagata ttataaatat gttgattcta ttttcatagc aatggagaaa atacattagc
     2161 aatatataaa agaaggtatc aagagtcacg gtgaatttat tccgaaaagt gaaaagaaca
     2221 aatataaaat ttaataaaaa tatagaacta aatag
//
LOCUS       DAFEIE010000137         2139 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFEIE010000137
VERSION     DAFEIE010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.144"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(51..1598)
                     /locus_tag="LP345_002815"
     CDS             complement(51..1598)
                     /locus_tag="LP345_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL1761535.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="LP345_002816"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="LP345_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL1761536.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          607 a          444 c          379 g          709 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttg
//
LOCUS       DAFEIE010000138         2102 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFEIE010000138
VERSION     DAFEIE010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.145"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            169..1539
                     /locus_tag="LP345_002817"
     CDS             169..1539
                     /locus_tag="LP345_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4357 domain-containing protein"
                     /protein_id="HBL1761537.1"
                     /translation="MMDKSNEEQTTLYTKYWRRLEEVFDNSKGMEDFFRYYLAAITGE
                     YSAKHILYQAFKDYWHKERDVSSDAELLQKLVRYAGYFARLYYNKPEGKYSEVLSDFQ
                     SMESMMPAPFVLGLSEWYYHDQFITEDQYIDAIKVVNDYQLRRYFNGDDTSRVSKAFP
                     SYLKSVRKYAKANGYENIVDIVIYVLVTRNQSNNMALPSDKALKSNLLNANAYAMRLA
                     RWLLEKIENRENSATLDMSNLSIEHIMPQTSTSYWEEKAGTSGEEYTGLVNTIGNLTL
                     VTNPDNSAAGNKDFETKKKIFEDTLHIRMNKDLYELTEWTSSDISARSEALINELITM
                     YPYLRSSGDYEHDGNREIFLEAQGIKATGYLNEDETVIIHSGSEIYSKIKDIASDSLD
                     ETRQELLDNGIIEETIGGLQFVQDYTASSVSNAAALLLGGSRNGWDYWKYDNGISIND
                     SLRNKK"
     gene            1560..1844
                     /locus_tag="LP345_002818"
     CDS             1560..1844
                     /locus_tag="LP345_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761538.1"
                     /translation="MDKNKLRYAILKLRDEKKNPFIELKGQVPEEDILEQTKFLSRNG
                     LLESMVWADNTVHIWGSVSLEGEKYLVENSGLAKAYALAKEVKNWIPFWG"
BASE COUNT          730 a          308 c          444 g          620 t
ORIGIN      
        1 ttgatttacc aacatgttta gacattttcc tctaggaaaa aattaactag caccacgcgt
       61 attgtttata ttaaattaga tgaccgtgat aatgcacagc aaatttttga aagtatcaat
      121 tctaccggtg aaagattgac tgcctcggat ttgattcgaa acttcatcat gatggataaa
      181 tctaatgaag agcagactac gctttatact aaatattggc gtaggttgga agaagtcttt
      241 gataattcta aaggaatgga agactttttc agatactacc ttgctgcaat aactggggag
      301 tattcagcaa agcatattct ttatcaagca ttcaaagact attggcataa agagcgcgat
      361 gtatcaagtg atgccgaatt gctccaaaaa ttagtgcgat atgctggtta ttttgcgaga
      421 ctttactata acaaacctga aggaaaatac tcagaagtat tgagcgattt ccaaagtatg
      481 gaaagtatga tgcctgcacc ttttgttttg ggattatctg aatggtacta tcatgaccaa
      541 tttatcactg aagaccaata tattgatgcg attaaggtag tgaatgatta tcagcttagg
      601 agatatttta atggggatga tacaagcaga gtgtcaaaag catttccttc atatttgaaa
      661 agtgttagga agtacgctaa agctaatgga tatgaaaata tcgttgatat tgtaatttat
      721 gttcttgtta ctagaaatca atcaaataat atggcacttc catctgacaa ggcattgaaa
      781 tctaatctat tgaatgccaa tgcttatgcg atgagattgg cccgttggtt acttgaaaaa
      841 atagagaatc gagaaaattc agcaacactt gatatgagta acttgtccat tgaacacatc
      901 atgccacaga ctagtacttc atattgggaa gagaaggctg gtacatcggg ggaagaatac
      961 acaggattag taaataccat tggtaattta acactcgtta caaatcctga taattcggcc
     1021 gcgggaaata aagactttga gaccaaaaag aaaatctttg aagataccct tcatattcgt
     1081 atgaataaag atttgtacga attgactgag tggacatcat cggatatttc tgccagaagt
     1141 gaagctctaa tcaatgaact gattactatg tatccctatt tgagatcgtc gggcgactat
     1201 gaacacgatg ggaataggga aattttctta gaggcgcaag gaataaaagc aactgggtat
     1261 ttgaacgaag acgagaccgt gattatacat tcaggttcag aaatttattc taagattaaa
     1321 gatattgcat ctgattcgct agatgaaact cgccaagagc tgttggataa tggaatcatt
     1381 gaagaaacaa ttgggggact acaatttgtt caagattaca ctgcctcatc tgtttcgaat
     1441 gcagcagctc tgctattagg gggtagccgg aatggttggg actactggaa atatgataac
     1501 ggaataagta ttaatgattc gctaagaaat aagaaataga gcatagaggt ggtgttaggt
     1561 tggataagaa caaactaaga tatgcaattc ttaaattgcg tgatgaaaaa aagaatcctt
     1621 ttattgagct taaagggcaa gttccagaag aagatatttt agaacaaact aaatttcttt
     1681 cgcgcaatgg cttactagaa tccatggttt gggcggataa cactgttcat atctggggga
     1741 gtgtttctct ggaaggggaa aaatatttag ttgaaaactc aggtcttgct aaggcgtatg
     1801 cattggcaaa agaagttaaa aattggattc cattttgggg ctaagataag tttttaaacg
     1861 gagaaggtag caaatcataa ttggtttgtt gccttttttg attgcccaaa aagaaaaatg
     1921 acaaagtata gagataaatg acatagtaca cgggaaaaat gacattgtat caccgacaac
     1981 gtctaaatag atgttgatat atatacgttc cgtacaaata attataaaaa tttaaatgat
     2041 ttgagtagaa gtatcagtga atatctcaag gggaatagct atctcaagat tcgattttca
     2101 ca
//
LOCUS       DAFEIE010000139         1980 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFEIE010000139
VERSION     DAFEIE010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.146"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(325..529)
                     /locus_tag="LP345_002819"
                     /pseudo
     CDS             complement(325..529)
                     /locus_tag="LP345_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(729..1745)
                     /locus_tag="LP345_002820"
     CDS             complement(729..1745)
                     /locus_tag="LP345_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL1761539.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          558 a          459 c          309 g          654 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaaa attttcctaa ttgtgacatg gctgtcacaa
      541 ttccaaatgc tctccgaggg tattcgctgt cacaagtgac aacgaaaaaa ggagccgaaa
      601 gcgtgtcacg ctctcaactc cttttacgct ttattttgct tcatgcaaaa tattcgctta
      661 tcgtgaattt acgtcactaa acattgacgc aaatccactc tcactcatct gacttttctt
      721 attcggtatc acttctctgt cacatccaac cccaaaagcc acgtatccaa ttcttttttt
      781 aattcgtctg cagattcctt aaacgtctct cgtaaatgat tcgttaactc atcattttga
      841 ctttcttgct tcagcaaatt ccgatattta tattttgtat gtctagcaat tatcgaccaa
      901 ttagaaggct cagctatcaa accatcaata actattttat caataggttt tatatcaatc
      961 ggcaaaaaat gcgggcttgc aaaactatct aagctttcct gaaccatcgc atgccaatcc
     1021 gttgctttgc cacgtcttag ctgcatttct aaccgccacc acgtatcgat ttcttttggc
     1081 acgattactt tttttcgttc ctgctctagc tttttgttgt acagtcgcac ttggcgctca
     1141 ctggcacgac tgccccagta cgctgtttct agcttgccag aacggccgta gattggctta
     1201 aaagaaatcg ggtctacaat acgatactga gtaataaagt catccggcac atctacaata
     1261 tcgcaggcaa tatccgcccg ggaaaaatgc ggatctaaaa ataggtcatg aatgaatcct
     1321 ttcatggaac tagctaaaaa ctggcctatc ttattcggat taaaatcaat acgacctttt
     1381 ccttcatgaa atttaagtat ttcgatatac gcaatatctt ctccatattg atcgaataat
     1441 tgccagccgt ttatcccaac tgatttcaaa tatccctgat tttcgttcaa acgcattaat
     1501 tgctcgaaat cgacaaaaac aactccattt ttcgtccaat aagctatggt atcattcagt
     1561 tttccgacaa ttgtaattcg atcaatcgac caatttaatt ttaggggggt ggtcgtacct
     1621 tgcacactta accgcctgtt agaaatacgg ttaagttttt cgagctgatt tatcgttgtt
     1681 cttttttctg cccctcgacc ttcaattttt gattgaattt cactcaactg attttcattt
     1741 gccattttcg tcctccaaac gaaaaaagag acttttggaa agaatttcca gagttcacgt
     1801 aaccctaaaa attcatatcc aaaaatctct agcttgaaga aacctaaaaa tattcgtata
     1861 atgaacctga gttacggagc taggtgaagt agtttccgta aatagtcgag agtgttagcg
     1921 cactgctcgg cttttatttt gctctttttt ctcgttttct ttgattatag cactcctcct
//
LOCUS       DAFEIE010000140         1918 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFEIE010000140
VERSION     DAFEIE010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.147"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1034)
                     /locus_tag="LP345_002821"
     CDS             complement(<1..1034)
                     /locus_tag="LP345_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1761540.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFT"
     gene            complement(1116..1805)
                     /locus_tag="LP345_002822"
     CDS             complement(1116..1805)
                     /locus_tag="LP345_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL1761541.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
BASE COUNT          636 a          427 c          337 g          518 t
ORIGIN      
        1 gtaaatacag tattatttcg gttgcttgct gcttcaccta gcccttgtac tcgtgtttga
       61 ttggcgactt gaccaaattg attcccgacg tctaataaaa taatagctaa aagcaaaatg
      121 gccaaatggc ttccgccaac caataaagca ataaagctta ttgtttgcat aacaagtccc
      181 atatacacga tttttctttc agaataagaa tctgccagtc gtcccacgat aggtgcagca
      241 actgctccag acaaaccaaa aatcgctaat atccctgctt cgaatgttcc ccaattgtag
      301 gcgggactgc tgatataaaa aatcaacgta gaccaaaaga tcgaaaatgt tccaaacatg
      361 aaaaatccac tgactgccgc ttctcttaat agacgttgag aagcaactaa atgcggcaaa
      421 cttttaagtg aatcaaggta tgaaacagct gtactacttt gctggacaga acgcggcatt
      481 ttccagtaaa gcagaagtgt aagaattccg actgcacata aagcaaataa atagatcatc
      541 cgccaagaaa aaagactggc aacaatacca gataccgtcc gagaaagcaa aatccccacg
      601 agtaaaccgc taagcaatgt acccatgacc ttccctcttg cttttggtcc cgctagtacc
      661 gcaccgtaag gaatgatgat ttgcggcacg atcgaaagta atcctattaa aaaagaagcg
      721 catgcaaata acgtaaacga aggcgcaaaa aaagcggcca acagagagac ggcagataac
      781 gctaccattc gaatgatcaa ttttggacga tccaccacgt cccctaaagg aactaaaaac
      841 agtaacccta acgcatagcc taattgggtc aacatcgtca atatcccgac tgcacttgtg
      901 ctaacagata aactagctgc tacttttgtt ccaatcggct ggatgtaata catattggca
      961 acaacaacgc cacaagtgat tgataatagt aaaataagcg aagttgttaa aggtgttttt
     1021 tcattactct tcattgattt cccccatttc ctatcttagt ttacaactta tggaaaagat
     1081 tggaaataga aaaatacaac tattcgccac acttattatt tgtgcttttg ttttccttgt
     1141 tttttcttgc gatctttata aatgaagaca actaacccta ctagcacagt aacacttgca
     1201 accaacgtga ctgcagtttt gttatatccg tgaaacagag cttctccacc acacgcatac
     1261 aacacagacg aagggatgac tccaatcacg atcgacaata tgatttgctg tagaggcaat
     1321 ttcatcgcat ctgcagcaaa attgaccata gaagatggaa taaccggtat catatagcct
     1381 aacattacac ctatttttgg atgtttcatt tgtcggattg cttgcaccca atgattcgtt
     1441 tcggttttct tatctaaaaa ttttaagcga tgcataagga aaattgcagt gatgttacca
     1501 agagcattac ccaaaatgtt gatgatcgca cctgtcagtg gtccaaagct caaaccagca
     1561 atgactccaa ctactgaagt aggaatacct ggaacagcac acatcaccgc tgtcaatacg
     1621 atcaagagta tcgatgcaaa agtcccatgc gaacgaatat gtgcgagtag ctctgcctta
     1681 ctcgctctcg gatttaaaaa taattggatg tctgtctgat attctaaata caaccgatag
     1741 cccactacca gtatcagaat gattcccaac gagatcaaca tcaatcggat tattttcttt
     1801 ttcatatttc ctcctgaaaa aaatggctct ataatttatg ggactgatga atcagaattg
     1861 attcttcagc cccattttca ttttaggtat taaaaaacat atcgttctct agtatgat
//
LOCUS       DAFEIE010000141         1894 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFEIE010000141
VERSION     DAFEIE010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.148"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(367..1485)
                     /locus_tag="LP345_002823"
     CDS             complement(367..1485)
                     /locus_tag="LP345_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761542.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
BASE COUNT          556 a          405 c          297 g          636 t
ORIGIN      
        1 ttttaaacgg tgttccagaa gtagcttctt cggaaataag ccgaaatttc acaaaaattt
       61 gagaaataat ttttgtcaat ctcttcttat ttcttgaagc tgaccacttc tgtcacaacc
      121 tcttccttaa acggtgttca aaagcttgca tctgcggtaa taagcccacc aaacaaaaaa
      181 tatgaagagc tatttttgct tgctgttctt attacttgat gcagaacagc tttttcacaa
      241 cctctcatac acggtgttta atcagctgac cttcggtatt agctcaaaaa acggaaaaat
      301 atgtgaaact atttttccgt ttgtttctct aatactcagg tcaaaacact gatttcacaa
      361 cctcttttaa taacgaagaa tcgctgtcag actcttttca tctggcgcat ctttttgatc
      421 caaaataaac actttcccgc cattaatgat cacatcatct gctaatgcat tcaacacttg
      481 acgccgatca tattctgttt caggatcttc accgaaacca tcagctaagt ttgacgtagc
      541 gataaataaa tgtgacactt ttccttcttt cgcagctgga acgatatcaa ctaactgatc
      601 gatgaatttc ttatctaaga gtttattgta ttcttttgat tcttgagctg cgagttcact
      661 tgacagcttc ttcgcccctt cttcgatatc tctaaaggat agctgcgcag gagaagcaga
      721 aatcgcaacg tctgcacaat aatagggatt tttagcaatt tttttgaaca tcgtctgatt
      781 ttctggtaat gcaaataaat aaatcggcca ttgttcagga ttttcgaaag aatccttcaa
      841 gtacgtatca acagcttggt aatagttgac ccaatcgatc tctacttctt catcttttgg
      901 atttacgcca tggaaagtta ctccatctcg ggctccgcct cctccattag aagagaagtt
      961 caaaccgcca cctgtcagtt cagatcccaa tgcagtaacg acatcaaccg gtgccccttc
     1021 tggtagagat acttctttta cttgtttgtt gctgacctca tacaatttca tggagtcgcg
     1081 gttcaatccc aataaataat aagaatagtt gaactgccca tttttgataa tagccagtaa
     1141 ataaggaaga tcacttacat agtattgatc gtctaccggg atactcaaac gatggatata
     1201 ggtctggtca gcagttataa tgaccgctac actcgtagtt gcactacgcc aaaacgaagg
     1261 atctcctaac aaattttcaa ttttttcttg gaacggggac cagtcatgtt cggaatattt
     1321 tttctcaaaa cgtttctttg cttctttcgc aaaatttttg aatttgatct gatctttttc
     1381 cacatcttga tgggcgacat gcgtattcag catgatcgtg acgaatggtc ctttagcgcc
     1441 ttctgaagtc aattgtgtca ataattcttt atcctttttt gccataaacg tacccctcct
     1501 aaaaaaatca ttcctttgtt tctatctaaa gtctaccaca acactatttt tccatacaat
     1561 aaaacgtatc taaaaaaata aaacggtttc tacggtttta aatttagcta tttttttaag
     1621 ttatcttcat aatttcctca attatttagc cccagtcttc aactattctt catgaaatgc
     1681 tgataaacta agaaaaagaa taaaagaggt ggatcttatg catttgatta tgattttcag
     1741 tttattaagt attatcagtt tatttgcttt cagcgcttcc cgcttattag atgcggaaac
     1801 acagcctatt cctgtaaaag tacgtaaaaa cgaccgctaa acttccataa cgcgcgttct
     1861 tatcctaaag ttttttcaga aacattgaaa ctct
//
LOCUS       DAFEIE010000142         1870 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFEIE010000142
VERSION     DAFEIE010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.149"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            24..1868
                     /locus_tag="LP345_002824"
     CDS             24..1868
                     /locus_tag="LP345_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761543.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT          613 a          342 c          311 g          604 t
ORIGIN      
        1 aagttttaga aaggaatacc tttatgtctt tttttaataa catatataat aaaaaagaat
       61 ctttttattt acgtataaag tggagcataa tcattatatt atcattgtta tttttaacag
      121 gaattgctta tttcttttat tttatttttt ctcctgcgga cagcaatcaa atgaaagaaa
      181 taaaagattc gtgggttttc tatacaaaag atgatcctga ttttaagttt gacagcaagt
      241 acactcgtac gattcctacc gtggataaag acgaaacatt cattatggaa acgacacttg
      301 aaaaaccgtt ggacgaagca aatttactaa tcaaaggaaa ccatcaatgg attactgtat
      361 atctaggcga aaagatttta taccaacgga aagattatca ggaagaaagc aatcccggac
      421 tctcattggc tgtgatagat ttaccagcaa attatatcgg aaaaaaattg acccttacag
      481 tctcatctcc ttatcagaac tatgctggac tgccaccgaa agtttatcta ggaacaactg
      541 gaccattgat tagttttatt tattcacaat cagtgccgca agtattgacg atgataatcg
      601 ctgtttttat cgctataggg acctttttct atacgatcta cttgatgtat aaacaaaaac
      661 gtcttgaata ctcacttatt ctcttaagtt gctttgcttt ggcattagga tttgaagctg
      721 tatcagaaga tattttaagt ggtattcttt ttgaaccatt cgttcattct tttttatctc
      781 atttatttat tatcttaacg tcagctttca tcatctgcta ctattggagc cgaatgtttt
      841 actataaaaa atggtacgga attttttgta cgttccaact tttgattttt atcggcgttc
      901 tgctttatgc aacttttact cctgcagaac ttcctgaatt aatgccgatt gctaatattg
      961 ctagtgttat aagcacttta gtcacttcac ttgcatgcat tggcgaagca tataagaata
     1021 accgttttta tgtagcttgt acaccttgga tcgtcttggt agccattatc cattgcttga
     1081 tttacatcca aacggcatta ggtatctatc aaacaacgat caattggtct acgattttat
     1141 atattatcat tctaatcgtt attatcagct acaatctaat cgatcacatc ttaaataccg
     1201 acaaagatcg gagacaagta gatttcttaa aaatcaaaaa tgatttgttg gagcaacatt
     1261 atgagcagct tcgacagcat atccaagaag taaatacact tcgcctggaa tttgtccaag
     1321 agatggagaa tctgcaagat ttaatgcata cggaccaaac aaaagctaaa aactatgtgg
     1381 aaaagatatt agaagaagca aaaaatttcg aaatgctgtg ttctttttgc aaccaccagg
     1441 tgacaaatct tatcttagcg cgttaccaga agttagctgc caaacggaat attcagataa
     1501 ccttccaagc agatcttccc gaagaacttc ctatcaacga tgacgatctg gctcaacttt
     1561 tgatccacgc tttagagcat tcctttagag aaactcatgc catcgaaaat ccactgtatc
     1621 gaaaaattta tttgtcgata cacgaacaag aggaacattt cgtcatttgt tgcgaacata
     1681 gtgcacatta cgatacaaac ctatttagtc gaggcatcac agaagaatta gatgatcagg
     1741 aacgttttga cttaatgatg atgaaagacg tagcggatcg ttacacagga acactaacgc
     1801 aggaaaaaga tactttcatt gatcggatca ctgttcaact ctctcgaaat tacccgaatc
     1861 ctgtataaaa
//
LOCUS       DAFEIE010000143         1863 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFEIE010000143
VERSION     DAFEIE010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.150"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..830)
                     /locus_tag="LP345_002825"
     CDS             complement(<1..830)
                     /locus_tag="LP345_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1761544.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     T"
     gene            complement(841..>1863)
                     /locus_tag="LP345_002826"
     CDS             complement(841..>1863)
                     /locus_tag="LP345_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL1761545.1"
                     /translation="ELKPKHERQNFLVGDDRLDHAVAFLWKDPQTGETVGASYQGTIV
                     DFNRFGKRGTYKHIDKNPTPNHGFNLKIGDPKHLKFFESSIDLLSYAALNREKLQDAW
                     LVSMDGLKHHVISHYVEESISELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDP
                     FTNKKIRCERGIPNDWQVPKEYKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVS
                     AHDVQSTFGKMLAKGEPVETIDLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKD
                     VNAGILLSYKAEQYYKGYKKHEHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQG
                     RQQERE"
BASE COUNT          459 a          402 c          327 g          675 t
ORIGIN      
        1 gtttcgactt gaaggatcgt acctggctgt tttcctaatt gaacaccttt ttcttttaaa
       61 taggcttcaa atgcttcttg tgtcgcttgg gtttcatttg gatcaagctt cgcatcaaat
      121 gcgccatttt gagcgattac ttgggctttt ccttcaaaat atggttcttt ttggaagttt
      181 ctaatctttt cctgcaattg ataaatcata tagagtgttg gggtttggac tctacctaaa
      241 gaaaaacttc ctggtatgcc tttttgctgc aagagtaaac tatacagtgg gctaccgttc
      301 atcccaatta accaatcggc gatctgacgt gcttgtactt cttcaaattt tggataggtc
      361 tcttctgcgt ctcgtaactg ttggaatccc tgataaatgg cttctttttc taaggagttg
      421 atccaaagtc ttttaaaggt ttttccttga ttggcgcctg cttgttgaat gattgaccag
      481 gcaatcagct ccccttcacg atcgctatca gtcgcgatca caatcgtatc agctgactgc
      541 agctgtcgtt tgacgacact aaactgcttt ttcttatctt taggaacatg atagtggtat
      601 tgattgggga aaataggcaa atgttctaat gcccattgtt tccatttttc atcgtacata
      661 tcgggcgaat ctaactcgac taaatgacca aaaccatacg tgatcacagt ttctcctgta
      721 aacaatcgat cttggatctc aaaataccca tcttttcggg tagctttaga aaagctatcg
      781 gcataagcct tcgcttgtga cggtttttct gctaaaatga cggttttcat agtgacgact
      841 tcactccctt tcttgttgtc tgccttgttg aaacaacatc gcacgttttt gctttctgat
      901 ttcttgttgc tggatctcat gcttcaattg atcattccaa tcctttttca cttcaggtac
      961 aaattcatgt tcatgctttt tatagccttt gtagtattgt tctgctttat aggaaagaag
     1021 gattcctgca ttaacgtctt ttatgttggc ttttctacta taaaaacgat caaagttgta
     1081 tgttccatct gcgcgttcac atactttcag ttccttcgcg accgtggtac atgcttcttt
     1141 caaatcaatt gtttctactg gttcgccctt cgccaacatc tttccaaacg tagattgaac
     1201 atcatgagca gacaccaatt gatttgtcag ctgtaaatta gtttcagttt tgtgtatggc
     1261 cataattgct tcaggttcaa cactcatttc ttttgcgact gcttcataag tagctttgta
     1321 ttctttaggt acttgccaat catttggaat tcctcgctca caacggattt tcttattggt
     1381 aaaaggatca acgattccct tcatctgttc tttttcataa aaaatatgtc ctgcacgatc
     1441 attgtccaca catatttcaa tcgattgagg aaatgtttgt tttcgtctta attcagaaat
     1501 cgactcttca acgtaatgac tgattacatg atgttttaac ccgtccatcg aaactaacca
     1561 ggcatcttgt agtttctccc gattcaatgc agcgtaactt aacagatcaa tactactttc
     1621 aaagaatttt aaatgcttcg gatcgcctat ttttaaatta aatccgtgat ttggcgtagg
     1681 attcttgtca atgtgtttat acgttccccg tttaccgaaa cgattaaaat cgacgatcgt
     1741 tccttgataa cttgccccta ctgtctctcc tgtctgtgga tctttccata aaaaagcaac
     1801 cgcatgatct aaacggtcgt ctccaactaa aaaattttgc cgttcatgtt tcggctttag
     1861 ttc
//
LOCUS       DAFEIE010000144         1854 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFEIE010000144
VERSION     DAFEIE010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.151"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..830)
                     /locus_tag="LP345_002827"
     CDS             complement(<1..830)
                     /locus_tag="LP345_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1761546.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     T"
     gene            complement(841..>1854)
                     /locus_tag="LP345_002828"
     CDS             complement(841..>1854)
                     /locus_tag="LP345_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL1761547.1"
                     /translation="ELKPKHERQNFLVRDDRLDHAVAFLWKDPQTNETVGASYQGTFI
                     DYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLNDTW
                     LVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDP
                     FTNQKVRCERGIANDWQVPKEYKVIYEEVAKEEKITPEAIMAIHKTENNLQLTNQLVS
                     AHKVNASFGQQLSVNDSIEAINLKDICREVAKELKACERVDGTYDFDRFYQEKGDINA
                     QILFSYKAEQYYKGYKNHEHEFVPEVKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQ
                     ERE"
BASE COUNT          471 a          399 c          322 g          662 t
ORIGIN      
        1 gtttcaactt ggtggatcgt acctggctgt tttcccaatt gaaccccctt ttcttttaaa
       61 taatcttcaa atgcttcttg cgtcgcttgg gtttcattcg gatcaagctt cgcatcaaat
      121 gcgccatttt gagcgattac ttgggctttt ccttcaaaat atggttcttt ttggaagttt
      181 ctaatctttt cctgtaattg ataaatcatg taaagcgttg gggtttggac tctgcctaag
      241 gaaaaacttc ctggtatgcc tttttgctgc aagagtaaac tatacagcgg gctaccgttc
      301 atgccgatca accaatcggc gatctggcgt gcttgtgctt cttcaaattt tgggtaggtc
      361 tcttctgcat ctcgtaactg ctggaatccc tgataaatgg cttctttttc taaggagttg
      421 atccaaagtc ttttaaatat ctttccatga tcggcgcctg cttgttgaat gatcgtccaa
      481 gctatcagtt ccccttcacg atcgctatct gtcgcaataa taatggtgtc ggccgattga
      541 agttgctgtt tcaccacctt gaattgcttt ttcttatctt taggaacatg atagtgataa
      601 tgtgtaggga aaataggcaa atgctctaat gaccattgtt tccaattttc atcgtacata
      661 tcgggcgaat ctaactcgac taaatgacca aaaccatacg tgatcacagt ttctcctgaa
      721 aacaatcgat cttggatctc aaaataccca tcttttcggg tagctttaga aaagctatcg
      781 gcataagcct tcgcttgtga cggtttttct gctaaaataa cggttttcat catgacgatt
      841 tcactccctt tcttgctgtc taccttgttg aaacaacatg gcacgttttt gctttctgat
      901 ctcttgttgg tagatttcat gcttcaattg atcattccaa tcctttttta cttcaggtac
      961 aaattcatgt tcatgatttt tatagccttt gtagtattgt tctgctttat aagagaaaag
     1021 aatctgagca ttaatatccc ctttttcttg ataaaaacga tcaaaatcgt acgtaccatc
     1081 cacgcgttca caagctttta attcttttgc gacttctcta caaatatctt tcaaattaat
     1141 agcttctatt gaatcgttaa cagaaagctg ctgaccaaaa gacgcattta ctttgtgagc
     1201 ggaaaccaat tggttcgtta attgcagatt gttttctgtc ttgtgtatgg ccataatagc
     1261 ttctggtgtg atcttttctt cttttgcgac ttcttcataa atgactttgt attcttttgg
     1321 cacttgccaa tcattagcga ttcctcgttc acaacgtact ttctgattcg taaatggatc
     1381 aactgcgccc attaattgtt ctttttcgta gaaaatatgt cctgcacggt cattatccac
     1441 acaaatctcg atggattgag gaaaggcttg tttctttctc aattcagata ctgcctcacc
     1501 aaaataatga ctgatcacat ggtgttttaa cccttccatc gaaactaacc acgtatcgtt
     1561 taactgatca cgatttagtg cagcatagct aagtaaatca atactactct caaaaaattt
     1621 taactgctta gggtcaccga tctttaggtt aaagccatga ttcgctgtcg aatttttatc
     1681 tatatgctta tatgtgcctc tctcaccaaa acgttcataa tcaatgaacg ttccttgata
     1741 actcgcccct actgtctcat ttgtctgtgg atctttccat aaaaaggcga ccgcatgatc
     1801 taaacgatcg tctcgaacta agaaattttg ccgttcatgt tttggcttta gttc
//
LOCUS       DAFEIE010000145         1810 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFEIE010000145
VERSION     DAFEIE010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.152"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            325..1188
                     /locus_tag="LP345_002829"
     CDS             325..1188
                     /locus_tag="LP345_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL1761548.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            1288..1770
                     /locus_tag="LP345_002830"
     CDS             1288..1770
                     /locus_tag="LP345_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL1761549.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
BASE COUNT          629 a          281 c          394 g          506 t
ORIGIN      
        1 aaagaaaaat ccaagcagcg ttctgatcag cagtttgaac aacaatttgc tttgtacagt
       61 aggtagtaag cggattaact aagggaataa aagatatttt taccgctttg tttacttaga
      121 atctgtcttc cccaaaattt atttttctaa aggtaaaaca tagataggca gataatacca
      181 attatccgtt acgaaacgct gcttgagaat tttctttaga tccatacaac attttctaca
      241 tctgactaaa ttggttcctg attcatcaag taattgactt tctttgataa tatgataaaa
      301 aggcaatcaa ggaggaagat aaatatgctt aaagatctga accaattgat cgattacatc
      361 gaagaacatt tgacagaagg actttcctat aaaataatag ccgaaaatac aggaatctct
      421 gaatatcaat taaaacgcat ctttacgttt attgcaggga tgtcgctaat ggactatatc
      481 aaaaaccgta gattggcttt ggctaatcgc gatcttctag atggatcaag agtgacagaa
      541 acggcgttta gatatggata tgaaacagtc gaaggttttt caagagcttt tcgtgattgg
      601 tcaggatatc tgccttcaga aatcagcaga tacggcatac aaaaatcttt tccacgcttg
      661 acatttttta ttgatgtcag aggaggaaaa tcgatggaat ttcgtatcga aaagaaagaa
      721 cagttttatg tggcaggtgt ggcgaaaaaa gttcctgtca aatttgaagg agtcaatcaa
      781 gaaatacaaa agttagcgca gacgatcacg gagactcaaa gggaagagat gcataagtta
      841 ggagatttat atccaaatca agtaatcaac gtttcttatg gatttgatgg agaccgcttg
      901 gaagaaaagg gcagtttgat gcacatgatt ggctttgcta cgacaaaaga aaatccgtac
      961 gctgatttag aaatgcttgc tatagaagaa cacacttggg ccatttttcc taataaaggg
     1021 ccatttcccc aaactttaca agatacttgg gggaaaatct atgcagaatg gcttccttct
     1081 tcagattatg ggttagtcga agctcccgag atctctttta caaaatgggg agaggatttc
     1141 agtaatgttt acagtgagat ttggattgca gtgaaagcaa aaaaatagtt aaaaaataaa
     1201 aatatcccta gaaaaaagag cgtaatcgtg tcatttccct ttaattttat gtaagatgaa
     1261 cttaatataa tagaaagggt gggagaaatg gcaaagtata ggatcgaaga aaaaccagat
     1321 tttacggtga cgggtattgg tgtggaattg aagagtagca atacggattt tgtcggtttg
     1381 gctgcagaga aacaagcatt tgagcaaaaa gttatcggta atggaacaat agatgcattg
     1441 aaacaagctg ctgaaaatca ttatttcttt acagtcaacg aaccctataa cgggaaaatg
     1501 atgtactatg tcggtgttca aacgagtcag gatgttccaa acactacgcg aatcatccca
     1561 ttcccaaaag gaacgtatct tgttgtaagc gctttagcag aatcgcctga agaattaaga
     1621 aatgatttga cgaatacggc ctttgggcat gttttaagag aagtagaaga ttacgcctat
     1681 gttgggggtc caaatgctgt agtcgaaatg ggagttacca acgggaaata tatgggagaa
     1741 atctggatac cggtagtcaa taaaccatga taatatagag gtcgtgaaag tagcgctttg
     1801 acctgagcat
//
LOCUS       DAFEIE010000146         1750 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFEIE010000146
VERSION     DAFEIE010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.153"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            327..1190
                     /locus_tag="LP345_002831"
     CDS             327..1190
                     /locus_tag="LP345_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL1761550.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            1295..>1750
                     /locus_tag="LP345_002832"
     CDS             1295..>1750
                     /locus_tag="LP345_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL1761551.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEK"
BASE COUNT          618 a          277 c          339 g          516 t
ORIGIN      
        1 tctgaaaggt ctcgtaagag acctctgtaa tcatcaaatc tttctctatt aatcgcagca
       61 tttttttgat agaatcattc atatagcata tcgtcctctc agttgtttat tttgtcgtga
      121 tttaatcata ctagagaacg atatgttttt taatacctaa aataaaaatg gggctgaaga
      181 atcaattctg attcatcagt cccataaatt atagagccct tttttcacct ttccaaacca
      241 aggctcagct attcaagtag ataacattat gttatgatag caaagaaatg tattaagaaa
      301 acctttcact atagagggag aaaaaaatga acgatttatt agcaactata tttacaggta
      361 ttattattga tgaaaatgaa aaaaactact ttgtccaaaa aaacggacaa acctttggct
      421 taagcaaatc agaaggtgaa cacaaaatcg gtgaagcagt tgaaggattc ggttaccaaa
      481 atcaaaaaca tgaaaatcgg atcactacac aaattcctaa aagccgtatc ggtcattacg
      541 cttttggaat cgttactgct acacgaaaag atttaggtgc gtttgtcgat atcggtcttc
      601 cagataaaga ctttgtcgta tctcttgatg aattgccgac aatgacagag ctatggccta
      661 aaaaagggga tcgcttgatg atttccctta gagttgatgc aaaagaccgt atttggggca
      721 gtttagcaga tgaaaaaata ttcaaatctt taagcaaata tggaacagaa gaaatgaaaa
      781 acaaagatgt gataggaaca gcataccgct tgaaattaac aggtacgtac gttttaacgg
      841 aagatttcta tcttgggttt atccatcctt ctgaacgata taatgaacct cgtctaggcg
      901 agcagataaa aggtcgagtg attggtgtcc gaccagacgg tgtactgaat ctttcattga
      961 agccaagagc atatgaagct atatcagatg atgcacaaat gattttaacc attttagaac
     1021 gttctgcaga tcagcaaatc aactttacag ataaatcgga tccagaagaa atcatgaaag
     1081 cttttggtat cagcaaagga gcatttaagc gcgcattagg taatcttttg aaacaaggat
     1141 tgattacaca agaaaacggt gtgacaaaac tagtcaaaaa atctaattga gaatcccttg
     1201 catgtttttc ttaactagct tataataatt ttaattaaca tagtgttata tcttttttta
     1261 tttgtaatta ttataaattg ttggggttga gtaaatggtc atgaatgcta tttcggcgat
     1321 gaaaaaaaca aaacagcagc tacatgaagc ggggtttaag ctgacaccgc aaagagaagc
     1381 tactctgctt gtgcttttgg aaaatgagaa agagcattta tctgcagaag aaatcttctt
     1441 tttagtgaaa aaaaagagtc cggaaattgg acttgctact gtttatcgaa cccttgaaat
     1501 cttgacagaa ttgaaaattg tcgataaagt aagttttaat gatggattag cccgttatga
     1561 tttgagaaaa gaaggcgcca aacatttcca tcatcattta ctatgcttga actgcggcac
     1621 gatcgaggaa gtagaagagg atcttttact tgaagtggag caagtagtag aagaacgtta
     1681 tcatttttta gtaaaagatc atcggctaac gttccatgga atctgtcagg aatgctatga
     1741 aaaagaaaaa
//
LOCUS       DAFEIE010000147         1743 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFEIE010000147
VERSION     DAFEIE010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.154"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(125..198)
                     /locus_tag="LP345_002833"
     tRNA            complement(125..198)
                     /locus_tag="LP345_002833"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(162..164),aa:Ile,seq:cat)
     gene            complement(387..1406)
                     /locus_tag="LP345_002834"
     CDS             complement(387..1406)
                     /locus_tag="LP345_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBL1761552.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1417..1623)
                     /locus_tag="LP345_002835"
     CDS             complement(1417..1623)
                     /locus_tag="LP345_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL1761553.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          501 a          362 c          302 g          578 t
ORIGIN      
        1 ttcattaatc cataaaagga tacataaaaa agccactcat ttgagtggca atgaagaaaa
       61 gctttagctt gtataatact cttcaaaaaa ttctaacaca gaacgattca aatggctacg
      121 ttaatgtacc ctgtaggact cgaacctacg accggacggt tatgagccgt ctgctctgac
      181 caactgagct aagggtactg gttgttgcca cataaagcca taaacaatca accagtagaa
      241 tgtgtggcaa caaacctgtt atcgcatagc ttggagtgtg actattatgg gtgatagtga
      301 agatatgcga taacatcact attttatcga atgattttta tagttgtcaa tatagttatg
      361 taatgctcct caacgaggag ctatttttat cgtttaggaa tatttaaata ccaacgtttg
      421 tcatggaaat cttgcgcacc gcctttagtg tttccctctg gatcattcgt tgcccgcatc
      481 atgacataga ctttcttatt agggaagtta cgcatgttaa aagatacatg atagccaaca
      541 tttccagaag tattataagc ttgatttaca tctgatctat aaattccatc agctcttact
      601 cgagctaatt ctttcccagt attgtaatcc ataatgaaga tatactcgta tttatagtta
      661 gcaatgtgcc atccagctac atgcaaattt gcattttcga tttctccaaa ctgatcaatg
      721 tgggcgtaat tcgttccatc tgtcagtgta ggattagctg caccagctcg tgttggatca
      781 atgacaggct tgttttcaga agttgttgga ttttcatcgg taaatccatg agctaaatca
      841 tatgctaatt tttctttact tacgcccatt tcagaaagat aaccgtaagg atctgtatga
      901 tcgccccaga tgttttgtgt tacccataaa tgcgatttga ttcccggttg gttataagga
      961 gtgtccaacg ttaatggaat accatatttc attgctgaat ctctagccaa ttcaacgtat
     1021 gccttgtagt ttttctcaaa cgttgcttta tcatgtgtgt gttgtaactc aatctgcaca
     1081 ggactgttgg cattagcata cgaaccagca ccgtactgta cataaccagg ttgaccgact
     1141 tgataaacaa ttccgccgtc tcccacaata taagcagtat aagcgctagt ccatgaacgt
     1201 tgcatatact gcgcttcatt gcgtcctgtt gctgtttcat tagccgtttc atgcagtaaa
     1261 atatactgat tatttgctac ttgtgagcta ccttcatttg cgcccaaatt aaattcattg
     1321 ttgatagtat aggcaaatcc gttaattggc aataaaaaaa gagccgttaa caggctcatc
     1381 gcagtaatag taattttctt tttcatatct atcctcctat ttatctgatg aaattttctt
     1441 atacgttcga tttgatacac ctaaaatact ccctagaaat gctccaaaac ctgtaataat
     1501 catcaccgtt atatctgtgt accgccagtt aacacctttt ccgacaagac cgacaaaagt
     1561 cgctaaagcg gggataacta ctatagcgat ccatttcaaa atatcaaagg ttctattgtt
     1621 catactatcc acctcccttc attggttggg ctactttctt tttcaatcgc ttgttttctt
     1681 ctatcaatat ttctctttct gaaagcaagg catcaatttg cccgtccagt tgttcaattt
     1741 tat
//
LOCUS       DAFEIE010000148         1686 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFEIE010000148
VERSION     DAFEIE010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.155"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(45..779)
                     /locus_tag="LP345_002836"
     CDS             complement(45..779)
                     /locus_tag="LP345_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL1761554.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1106..1516
                     /locus_tag="LP345_002837"
     CDS             1106..1516
                     /locus_tag="LP345_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBL1761555.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1509..>1686
                     /locus_tag="LP345_002838"
     CDS             1509..>1686
                     /locus_tag="LP345_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBL1761556.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYN"
BASE COUNT          537 a          294 c          325 g          530 t
ORIGIN      
        1 ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc cataaataat
       61 aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac tggtacccat
      121 gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg tacaagacgt
      181 ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag tgaagcaact
      241 aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc ttggaagaat
      301 ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa gaattcattg
      361 acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc taacacatgg
      421 tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat caattgtcca
      481 atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca agggaataga
      541 ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct gattccacca
      601 aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag catccagtca
      661 ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt acctagaacg
      721 attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga gtaatccata
      781 aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg aaaagcatcg
      841 gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat aaaaaaatga
      901 attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt taaaagttct
      961 ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt tttctcaaaa
     1021 attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta gtaaaatgaa
     1081 agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca ttattatttt
     1141 cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc ctggaagtat
     1201 cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc ctgaaaaaat
     1261 cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc ctgctggtgt
     1321 aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac tgggagcagt
     1381 cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag gtgtagaagc
     1441 tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg aaatggagga
     1501 gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg actttaggag
     1561 tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg aatcctctcg
     1621 tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc tataaagact
     1681 ataata
//
LOCUS       DAFEIE010000149         1623 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFEIE010000149
VERSION     DAFEIE010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.157"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            43..675
                     /locus_tag="LP345_002839"
     CDS             43..675
                     /locus_tag="LP345_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL1761557.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(677..1582)
                     /locus_tag="LP345_002840"
     CDS             complement(677..1582)
                     /locus_tag="LP345_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL1761558.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
BASE COUNT          492 a          334 c          295 g          502 t
ORIGIN      
        1 cccgcttctt tgctatacta aagaaaaacg aggtgaaccc acatgaaaaa aatcgaacct
       61 attccacctt ctcttcctct tcttacaaag ggagagtttt atttagaaga tgaggagatc
      121 ttctctggtc ttctgatcaa cgggggtgac caaagctatc tcgatgccaa aaatatggta
      181 ttaagagaga gtcatatcca aaaacttacg atgcaaaaaa cagttttacg tcattttgaa
      241 tgcagtaatg tcatttttga aaaatgtgat ttttccaatc tggagtggat tggtggcagt
      301 ttccaccaag tcgtgtttca tcaatgtaaa ttaacaggta cgaattttgc cgaaagttat
      361 cttcgagact gtactttcac tgattgtatt gcttcgatgg cttcctttag tagtacaaac
      421 ttgaaagctg tctccttcga tcattgtcaa ttagaagaca gcgaatttta tgaggtcact
      481 tggaaaaacc tttttttgtc tgacaatcag ttgaccggtt cgaactggtt tcgaacttct
      541 ctgaagggat tagactttac gactaatttc ttcacagcaa tcgctttatc tcaagattct
      601 ttggcgggac taatcgtcaa ccaagagcaa gcacttgtga tcgcccaagc ccttggtttg
      661 cagatcaaag actagatcaa cgaatccgcc gccacagtgc aataagcatc caaatagata
      721 agaccaaact gatgatcaag gcgattcccc atccgaaaac ggaatgggta aagggtaact
      781 ggagattcat tccgaagaat cctgtcacaa tagttggaac ggtcaagatc agcgaccaga
      841 ccgtcaaaaa tttcatcgtg tcattcaagt tgttattcag caaattatta taagtgccag
      901 agagctggtc taaaatctgc gaagctaagt tcgtcatttc aactgcttgt cgtgcttcga
      961 tcagcgcatc gtccaactct tctttttcct tttctgacaa cttgcgataa atagccaatg
     1021 ccttgatttg ttctaaaagt actacatttt gttttgttcc tgtaactaag taaaccaaac
     1081 cgatctctaa atctgaaagt tgcagcagat tcttgttcgt tgttttttct cttaatttca
     1141 gattaagccg ctgacgttca ctattcactt cctcgattaa aggaaaaaag gaatcagaaa
     1201 tcaaaaacaa tgtacgaaac aataaactgt atacactcat gtctggcatt cgttccaaaa
     1261 gcgatcgaat tagtcgaatc acgtactcgg tattcggcgt ggtaaatgta aacaaaccgt
     1321 cttcttttaa aataaaagcg ataggactag tttcataatg attatcgact ttttgctggt
     1381 gcggaacatt tgatacaagc agtaacgctt catcaaaaga atcgtactct acgcgcgccc
     1441 gttcattttt atctagagaa taagtcagca tctcgtcact aatgccatat tcttctttta
     1501 agtttttaac agctagcaca tcgttttgct gtacattgat ccaaaaatta cggtcttgat
     1561 taaaatagtg tttttcccgc atactctatc ctcctgacat ttgtttccag tataaagaaa
     1621 aaa
//
LOCUS       DAFEIE010000150         1584 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFEIE010000150
VERSION     DAFEIE010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.158"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            292..1479
                     /locus_tag="LP345_002841"
     CDS             292..1479
                     /locus_tag="LP345_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL1761559.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
BASE COUNT          467 a          296 c          316 g          505 t
ORIGIN      
        1 ttttaacctt ccggttttga ttggataacc ctatgaacca tcgttatttt aatttggtat
       61 taactcattt cttttgagat aatatattta ttggattgag aggctaagcc gttcccccct
      121 tgggccattg aacccgcact cgagagactg gctcctctct ctgataagtg gattgcgtat
      181 gagttagatg ttgaaagtcc ttactttact ccgtatctcg tacaaggtag tgacgctttt
      241 cagttgagtg gatttcaatc caaaattctt tttttgaaag gtcagatata catgtacttt
      301 ttaggcattg atatcggtaa acgcactcac gttgcttcta tcatgaacga ggaaggaaag
      361 gtattactaa aaggtttttc atttcctaac accactgaag gagcagagtc attaattgag
      421 cgaatggtcg actattccgg agcacccagt gactttgtta tagggatgga agccacgggg
      481 cactattggc tgtccatctt ttcatacctt cacgaatcag attatttgat tcacgttgtg
      541 aatccccttc aaacagacgg atggcgtaaa ggtacagaaa tacggaaacg aaaaaacgat
      601 attattgatt ctgttttgat tgctgactta atgcgctatg gctcatttgt cgaaacggtc
      661 ttatccgatg aaaatgtttt ttctttgaaa caactttctc gttaccgaac ttatttagta
      721 ggtacagcga gcgacttcaa aagaaaaatt atagccgtat tggatcaagt ctttccagaa
      781 tacgcgacga tttttaccaa gcagggcgtt ttcggaaaag cttctaaaga gttattgctg
      841 gcgtttagtg ccccgatcga cttagaaaac atttcctcag aaactttggc ccaatactta
      901 gctgagttaa gcaggaaccg aatcaaggca gaaaaagcgg accaattgaa gcaagcagct
      961 tctaactcct ttggagtaaa atttgctcaa gaagcgttca ccttccaact acgttcaatg
     1021 attgaacaat taaaattcat tgaaagccaa ataaaggaaa cggaaagaga aatcaagcac
     1081 ataatggaca ctttaaattc tgttattctc acaattcctg gaattggtcc tataaacggt
     1141 gcgactattc ttggtgagat cggagatatt caaaaatttt ctaacccgaa aaaactcgtt
     1201 gcttacgctg ggatagacgc ttccgtgaca caatcagggc aatatgaggc aacgcataat
     1261 gttatgagta aacgagggtc tccatatttg cgaaaagcct tgttttcggc ggctttagta
     1321 gcttctcaat gtgatcctgt ttttagtgcg ttttaccaga aaaaagtttc cgaaggaaaa
     1381 catcatctaa ctgccttagg tgcggtttct cgtaagcttt gttacgtgat tcatgctatt
     1441 ttgactaaaa acgagcctta tataattgtt tctgattagc tattgaacat tcaaaaaaac
     1501 taatggtaag aagcttattt gttgtaccct tttttcggaa ttatctgtta taaaatattt
     1561 tttgatttgg ctaattttta cttg
//
LOCUS       DAFEIE010000151         1581 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFEIE010000151
VERSION     DAFEIE010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.159"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            128..1297
                     /locus_tag="LP345_002842"
     CDS             128..1297
                     /locus_tag="LP345_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1761560.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          568 a          254 c          258 g          501 t
ORIGIN      
        1 atatcccata ttttaaaata aaagatagcg taaaatattt tgtgtaaata gaaatttagg
       61 gtagaaaaaa aagtccattc tgtaaaatta aagttaccac acagaaattt tataggagga
      121 ctttctcatg actaaattta ctatagaaat tatgcaaaca ctactcaata aaggggattt
      181 agatgaatta tttcaggatc atttagagcg agcgattaat tcacttctac aagcagagct
      241 aactgctttt ttagattacg aaaaatatga tcgaaatgga ttcaattcag gaaattcccg
      301 taacgggaat tattcacgta catttaaaac agaatatggc gagttgaatt taactattcc
      361 tagagatcgg aatggcgaat tttctcaaca aacactacca gcatataagc gaaccaatga
      421 ttcattagaa acgaccatta tccaattatt tcaaaaaggc attactatgg ctgaaatctc
      481 caaattaatt gaaaaaatgt atggtcacca ctatacgcca caaacaatct ccaacatgag
      541 taaattggtg gctgaagatg ttttagcttt taaagaaaga acgttagaag ccaattattc
      601 cgttatattt atggatgcga cgcatatccc tgtgaagcga cagactgttt cgaaggaagc
      661 agtgtatatt acgattggta ttcgtttgga tggaaccaaa gaagttcttg ggtttactat
      721 tgccccaact gagtctgctt atatttggaa agaagttctt caagatctta gaaaacgtgg
      781 gttagaagaa gttttattag tagtgacaga cggattaagc tgtattgaag aaagtatcca
      841 tagtgtgtat ccgaatgccc aatttcaaca atgttgtgtg catgtatcta gaaatatcgc
      901 tcataaagtt cgtgttcgag gtcgaaaaga aatttgtgag gatttcaaat tggtttacca
      961 agcgaattca aaagaagagg cattggatca catcgacttt atgactagga aatggaaaaa
     1021 gcagtatcca agagtcgtca atttactctt gaatcctgcc ctattaacct tttataattt
     1081 ccctcacgcc atcagacgaa caatttattc gacgaacctg attgaaggct ttaataagca
     1141 gctaaaacga tatactcgaa gaaaagaaca attccctaat gaagaatctc tagagagatt
     1201 cttcatttct caatttaatc aatataacca aaaattttta ggtagaattc acaagggatt
     1261 taaagaaatt caggatacat tagagtcgat gatttaactg taattaacag aatggatttt
     1321 ccatttacat ataattcttg acgctaccat aatctaaata accatcatat tcatctacta
     1381 cttatataat tgagttttat taaacttttt aagtttctat tctatcaaat atttaaacaa
     1441 tctctgcatc cgaaaagact acctcgtata gttttactaa caatattttt attagcgtgt
     1501 tcaaatcctg atttcttgta tcaattattt tctgttcact ttcaataaga aaaaagtctt
     1561 tacttccatg gataataata a
//
LOCUS       DAFEIE010000152         1577 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFEIE010000152
VERSION     DAFEIE010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.160"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            535..1554
                     /locus_tag="LP345_002843"
     CDS             535..1554
                     /locus_tag="LP345_002843"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL1761561.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT          541 a          257 c          332 g          447 t
ORIGIN      
        1 attttttgca ttatctacag ttcaacttat aatctgttta atgggacatg tgggtgccaa
       61 ccattttttg ttatgcaata gtactattta gttgttgcat ggatccgtag taaaagtcca
      121 agtacaacga gttgcgccag tttacatagc gttttgtatc cagaatgttg actaaaacaa
      181 aagttcctat gtcaaccgtc aacagagaca atctgtccgt tgcaggacct gacagattta
      241 gaaatgttca atctgtctct tatgtatttt aaatcaatac tcactaggag aagtttccta
      301 acctcctaat agtaatgctg gtagtaacat tgtcaaaact gcttcctctt aggaacaagc
      361 aaagcataac gagtgtaaaa ataaaatgta gactattgta acatatcatt gattatttca
      421 agtaaaaacg ataaaagaag taaacaaaca cttaaaaaca atggaaatta gtcccaactt
      481 taagaaatgt atactataat ggaaattatc aattatttat ttggaggaat atccatgaaa
      541 caaaaaatcg cagttcttgg tcctggatct tggggcactg ctttagcaca aacattggca
      601 gaaaacgggc atgatgtccg tatttgggga aatgtacctg aacagattga tgaaatcaat
      661 aagtatcata caaatcagca ttttttacct gatttgacga tcccagaatc gattatcgga
      721 tataaagaat tggcagaagc agtggataac gcagatgcta ttttatttgt tgttccaaca
      781 aaagcgattc gttcagtcgc acaggaactt attggtaaaa tgaatactaa gccaatcatt
      841 atacatgcaa gtaaaggact agaacaagat acgcataaac gaatctcaga agttttggct
      901 gaagaaattc cagaagaaaa aagacaggca attgttgtat tatctggtcc tagccatgct
      961 gaggaagtgg cagtacatga tatcacaaca attacagctg caagtattga tcaaaaagca
     1021 gcagcctatg tacaaaaact gttcatgaat gattatttca ggatttatac aaataatgat
     1081 gtgattggcg tagaaactgg tgcagcactg aaaaatatca ttgcaattgg tgccggcgct
     1141 atccatggat taggattcgg agatgatgca aaagcagcaa tcatgactcg aggattggca
     1201 gaaatcagcc gtcttggtgt cgcgatgggt gccaatcctc tgacatttat cggtttgagt
     1261 ggtgtggggg acttgatcgt tacttgtaca agtgttcatt ctcgcaattg gcgtgccggt
     1321 aacttgttag gacagggaca taagctggaa gaagttctag aaaacatggg aatggtcgtt
     1381 gagggtgtgg caacgacaaa agcagcagta gagctagctc aacagctagg tgttgagatg
     1441 ccaattactc aaacaatcta taatgttttg tataatggag aagatatcaa aaaagcagca
     1501 aaagaaatca tgttacgtga cggaaaaatg gagaatgaat tttctcttcg ttaaatagat
     1561 gatcaatagt taatcgt
//
LOCUS       DAFEIE010000153         1570 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFEIE010000153
VERSION     DAFEIE010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.161"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..1309
                     /locus_tag="LP345_002844"
     CDS             <1..1309
                     /locus_tag="LP345_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBL1761562.1"
                     /translation="SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHY
                     PKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIR
                     AYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDS
                     IEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEY
                     SYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISEC
                     TIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCN
                     HLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEK
                     AKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1439..>1570)
                     /locus_tag="LP345_002845"
     CDS             complement(1439..>1570)
                     /locus_tag="LP345_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1761563.1"
                     /translation="RRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          649 a          135 c          267 g          519 t
ORIGIN      
        1 atcattaaaa aaacattata cagagccttg ggaagatgaa gtttttagag taattattga
       61 atataacaat gttcctattg gatatggaca aatatataaa atgtatgatg agttatatac
      121 tgattatcat tatccaaaaa ctgatgagat agtctatggt atggatcaat ttataggaga
      181 gccaaattat tggagtaaag gaattggtac aagatatatt aaattgattt ttgaattttt
      241 gaaaaaagaa agaaatgcta atgcagttat tttagaccct cataaaaata atccaagagc
      301 aataagggca taccaaaaat ctggttttag aattattgaa gatttgccag aacatgaatt
      361 acacgagggc aaaaaagaag attgttattt aatggaatat agatatgatg ataatgccac
      421 aaatgttaag gcaatgaaat atttaattga gcattacttt gataatttca aagtagatag
      481 tattgaaata atcggtagtg gttatgatag tgtggcatat ttagttaata atgaatacat
      541 ttttaaaaca aaatttagta ctaataagaa aaaaggttat gcaaaagaaa aagcaatata
      601 taatttttta aatacaaatt tagaaactaa tgtaaaaatt cctaatattg aatattcgta
      661 tattagtgat gaattatcta tactaggtta taaagaaatt aaaggaactt ttttaacacc
      721 agaaatttat tctactatgt cagaagaaga acaaaatttg ttaaaacgag atattgccag
      781 ttttttaaga caaatgcacg gtttagatta tacagatatt agtgaatgta ctattgataa
      841 taaacaaaat gtattagaag agtatatatt gttgcgtgaa actatttata atgatttaac
      901 tgatatagaa aaagattata tagaaagttt tatggaaaga ctaaatgcaa caacagtttt
      961 tgagggtaaa aagtgtttat gccataatga ttttagttgt aatcatctat tgttagatgg
     1021 caataataga ttaactggaa taattgattt tggagattct ggaattatag atgaatattg
     1081 tgattttata tacttacttg aagatagtga agaagaaata ggaacaaatt ttggagaaga
     1141 tatattaaga atgtatggaa atatagatat tgagaaagca aaagaatatc aagatatagt
     1201 tgaagaatat tatcctattg aaactattgt ttatggaatt aaaaatatta aacaggaatt
     1261 tatcgaaaat ggtagaaaag aaatttataa aaggacttat aaagattgat tatataatat
     1321 atgaaaagct attataaaag acattagtat taaatagttt aaaaaaatga aaaataataa
     1381 aggaagtgag tcaagtccag actcctgtgt aaaatgctat acaatgtttt taccatttct
     1441 acttatcaaa attgatgtat tttcttgaag aataaatcca ttcatcatgt aggtccataa
     1501 gaacggctcc aattaagcga ttggctgatg tttgattggg gaagatgcga ataatctttt
     1561 ctcttctgcg
//
LOCUS       DAFEIE010000154         1529 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFEIE010000154
VERSION     DAFEIE010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.162"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..903
                     /locus_tag="LP345_002846"
     CDS             <1..903
                     /locus_tag="LP345_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBL1761564.1"
                     /translation="GFTKQSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSY
                     PLVGPATWDGKVYVQNLFNAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGF
                     KACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESL
                     IGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGW
                     KVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELG
                     MICGKLDRQYYSASAISSIVIPPK"
     gene            916..>1529
                     /locus_tag="LP345_002847"
     CDS             916..>1529
                     /locus_tag="LP345_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBL1761565.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLA"
BASE COUNT          511 a          218 c          358 g          442 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga catttacaaa tggacaatgg atgggcgtag tacaacctac gacggttgat
      301 ggatttaagg cctgtactga tccaagacaa gcagcatatg cttttgaacg aaactatgaa
      361 cgtccggcag cgacacatcc tgaacgtcaa gattatgcag ttaactggta taacaaattt
      421 aaagatttaa aaccaggagg agctactgga gaagcaggac taaaacattt agagtctttg
      481 attggacaac gaattggcaa tggtcagtgt tatggcttgt ctgcagaata ttcaggatat
      541 ctgggtggtt gtggcatggg tgctggaaca aaatatggtt taactcatgt gataggaaat
      601 acttctgcag catctgatat tggtattgcc tatgattggt ctgctgttgg ttggaaagtg
      661 attcaaaacc ctagatatga tcaattagta gttggtgcaa ttattaattg ggcaagaggt
      721 ggacaagtgg gttcatggtt tgcagacgga acttatggac atactggcgt tatccgaggc
      781 ttagctaatg gtcgtatgca aacttatgaa caaaacacag agttaggtat gatttgtgga
      841 aagttagatc gccagtatta tagtgcaagt gcaatttctt ccattgtcat accaccaaaa
      901 tagggaggtg atttaatggc aaagtggaat gtcatattaa gtacaacaga accctataat
      961 tacgtgggga tgattcaagt tcgacaaggc aataaaaaca ctgaagttat ggaagctaca
     1021 attgtcgaaa atggtcttcc atatgattta tcagaatgta aggtatattt tgaatcagtt
     1081 gttggcggaa aatatccagt ccaattagaa acaagaattg tggatgctaa aaaagggaaa
     1141 atcaaatata tttttgataa atattccatg cagtgtttgc atcgacaaac agccaatttc
     1201 attatattta aaggagaaga cttgattgga acaactcaag acttctccta ttttgtcatc
     1261 aatgctgttt caaaaacaga aggagaaatg ggttcttatt ggcaatcaat tgaagattta
     1321 attgctgata tgacagattt tattaatgaa aataaaggcg attttacgga ctggatgaat
     1381 gaaaggaaag aagaatttga tcgctggaga gaagaacagg agaatagttt ccaagattgg
     1441 agagaaggac aagaatcaga ttatttgtca tggtttgaat caatcaagga tattttgaag
     1501 tctatcgatc caggtggagt aatgttagc
//
LOCUS       DAFEIE010000155         1502 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFEIE010000155
VERSION     DAFEIE010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.163"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(312..611)
                     /locus_tag="LP345_002848"
     CDS             complement(312..611)
                     /locus_tag="LP345_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761566.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(617..847)
                     /locus_tag="LP345_002849"
     CDS             complement(617..847)
                     /locus_tag="LP345_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761567.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1097..1297)
                     /locus_tag="LP345_002850"
     CDS             complement(1097..1297)
                     /locus_tag="LP345_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1761568.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          533 a          243 c          219 g          507 t
ORIGIN      
        1 attgtgagat aataataaag aagagtttaa agcgttcccc aaaaaccact gccccataag
       61 tgtgttacgc tttaaactct tttatatttg aagccattaa aaagcatacc atatttttga
      121 aaaaaagtga gaaaaaaggc ttataattgg agtggtagtt aattagtgac ttatttttga
      181 ttttatagca ctgatactat aaaatataga tatcatcata ttacacaatc ttaatactaa
      241 cttaaaaaat atctcctttc ataagtatgg tgataaaatc cgttccgggc taccttttta
      301 ggtagcctac tttaatcttt gtatctttct ggatcaacga aagtatactt tatatagtca
      361 taacgccgat gatcgcttcg agcgtctagc acatcagtca cgatatcaaa caaaaaatat
      421 acgtctttct tcattctagt tttcgcagca gggattttaa agtagttctt attagaatag
      481 tagagattaa ttaataagct atcttcgatt gctaaaaaga aaacttctga atcccacacc
      541 ttataaaaat ctttgacaaa tctattcgaa ggatcaaatt taaaccataa ttgcgtctca
      601 ttaaaaagca taaccattac tccgatctat ttttaaactt agtctctacc tctaatatat
      661 atcgagtttt tattttgcct tcagagaata ctgtttcttt ttttgcagtt acaggttgtt
      721 tattttcgga aaaagctaat atagctaaaa ttgaaacatc catctggaat ttgtcttttt
      781 cgttgctttg ctcataaaaa tctgcatatt catcactaat attttttcta ataaattctt
      841 ccatcataaa gatcacctcg aaaagagtat acgaacaaac gttctttttg taaaggtgga
      901 atttattata ctaaataaat aggtgaacaa gtacttgtgc caaattatgt gccaaaaaaa
      961 atcgaattta ataaaacaca aacaaaaaga aatcctatta tgataacatt tcttataata
     1021 acaaacacaa cagaagacgt gtaatagtta gtcaggaacg tacaaataac ccctgtatcc
     1081 tttgcggtac agggggttat tttgtataag tagacattgt agtttctaaa ctgctatgtc
     1141 ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata gatgcatgcg
     1201 tatgtcttag tccatcaata aacagtcgaa gagaaaatag ggaaaaattg attactaaag
     1261 aaaaacttac taggtcgacg gtgtagttga ttttcatact tcaatagatt cgaattaaac
     1321 gatttcgatt ggcttatacc agtcctatcc aacgaaagat atatcgttct taactctagc
     1381 ggtataactt gaagctttac gtaaagccaa tgggaatgaa ctggagatga ctttttatta
     1441 tttttagtaa tagctgatgg gttaatactt acaactttcc ttttcaaagt accatataaa
     1501 aa
//
LOCUS       DAFEIE010000156         1463 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFEIE010000156
VERSION     DAFEIE010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.164"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..738
                     /locus_tag="LP345_002851"
     CDS             <1..738
                     /locus_tag="LP345_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HBL1761569.1"
                     /translation="KDKQIVCGNCMKKAGYGMTTPYKIIRSLNLEDLDKDPSEKRKLN
                     ISDHTAQNNHDIGNDRMRTTEEMVEFCLKYGYGKGMTKKWTTHHFNLISDQLNSDEYV
                     IFCFVGLHNYISSTKHDNNYAYALTNKRLIVAQQKMIGNNVQSIILDNLNNISKKRGV
                     LLGTLTIDTLGKVLNVAVDKDTVDRISDSLNEIIYNLKRRNISATNSNTSTISSASEI
                     RKYKELLDDGIITEEEFNKKKQELLDL"
     gene            834..1136
                     /locus_tag="LP345_002852"
     CDS             834..1136
                     /locus_tag="LP345_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761570.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          552 a          192 c          236 g          483 t
ORIGIN      
        1 aaagataaac aaattgtttg cggcaattgt atgaaaaaag ctggttacgg tatgactact
       61 ccttataaaa taataagatc tttgaattta gaagatttag ataaggatcc atcagaaaaa
      121 agaaaattaa acatatctga tcatactgca caaaacaatc atgatatagg taatgataga
      181 atgagaacca ctgaagagat ggtagaattt tgtcttaaat acggctacgg taaaggaatg
      241 actaaaaaat ggacaactca tcattttaac ttaatatcag atcaacttaa cagtgacgaa
      301 tacgtaatct tctgctttgt aggattgcat aattatatct catcaactaa gcatgacaat
      361 aattatgcat acgcattaac taataaacgt ttaattgtag ctcaacaaaa aatgataggc
      421 aataatgtac aaagtattat attagacaat ttaaataata ttagtaaaaa aagaggagtg
      481 ctgttgggta cattaactat tgatactctt ggtaaagtat tgaatgttgc agttgataaa
      541 gatactgttg ataggataag tgattcttta aacgaaatta tttataattt aaaaagaaga
      601 aatatttctg ctacaaattc caatacatca acaatttcct cagcttcaga aataagaaaa
      661 tataaagaac tattggatga tggaatcatt acagaagaag aatttaataa aaagaaacaa
      721 gaattattag atttataata tctatcaaag aagatgggca tttaatttag ctcatctttt
      781 tctatttaca atacaaacat ttgttcgtat actctttttg aggtgaactt tatatgttaa
      841 tggaaggaaa aacacaatta tggtttaaat tcgatccttc gaatagattt gtcaaagatt
      901 tttataaggt gtgggattca gaagttttct ttttagcaat cgaagatagc ttattaatca
      961 atctctacta ttctaataag aactatttca aaattcctgc tgcgaaaact agaatgaaga
     1021 agggtgtata ctttttgttt gatatcgtga ctgacgtgcc ggacgcacgt agcgatcatc
     1081 ggcgttatga ctatataaag tatactttcg ttgatccaga aaggtataaa gattaaagta
     1141 ggctacctaa aaaggtagcc cggaacgaat tttatcacca tacttgtgaa aggagatatt
     1201 ttttaagtta gtattaagat tgtgtaatat gatgatatct atattttata gtatcagtgc
     1261 tataaaatca aaaataagtc actaattaac taccactcca attgtaagcc ttttttctca
     1321 ctttttttca aaaatatggt atgcttttta atggcttcaa atataaaaga gtttaaagcg
     1381 taacacactt atggggaagt ggtttggggt gcgctttaaa ctcttcttta ttattatctc
     1441 acaatttaac ccaaatgtct ttc
//
LOCUS       DAFEIE010000157         1456 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFEIE010000157
VERSION     DAFEIE010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.165"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            108..1040
                     /locus_tag="LP345_002853"
     CDS             108..1040
                     /locus_tag="LP345_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBL1761571.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..>1456
                     /locus_tag="LP345_002854"
     CDS             1112..>1456
                     /locus_tag="LP345_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761572.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          227 g          420 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caagat
//
LOCUS       DAFEIE010000158         1451 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFEIE010000158
VERSION     DAFEIE010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.166"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            105..1406
                     /locus_tag="LP345_002855"
     CDS             105..1406
                     /locus_tag="LP345_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1761573.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          476 a          293 c          264 g          418 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
     1441 ctcactctat c
//
LOCUS       DAFEIE010000159         1421 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFEIE010000159
VERSION     DAFEIE010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.167"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            96..1388
                     /locus_tag="LP345_002856"
     CDS             96..1388
                     /locus_tag="LP345_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1761574.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          462 a          291 c          257 g          411 t
ORIGIN      
        1 accagcatct tttttatttt ccaaaacata tagaaaagac accttgaaat cctttagaat
       61 taatttggcg aaccaaccca aaaggaggaa tcaagatgtc ttacactcac cttatcaaag
      121 aaacattaga tattctagac ttatcagtta cttttaacga aaattgtctc acaaaagaaa
      181 aatacaaagg gcaaatctgt catatttatc gtggaaactt gatttataca gcccaagaat
      241 gcatccactg taaacaccag attgcttcag atattgtgcg ttggggtaca acaaccgtcc
      301 ggttgttaat gaacgatgtt tctgaatacc gtacctacct cgaattgaaa aagcaacgct
      361 tcaaatgcaa agcttgtcag cggacctttg tcgcagatac ttctgttgcg aaaaaacatt
      421 gtttcatcag tgagaaagtc cgctggtctg tcgtgactcg tctgaaaaaa aatacctcaa
      481 tgacagagat cgccgctcag aaaaatctat cggtctcttc tgtttaccgt attatgaagc
      541 gattttatcg tccgttgaat ccttttcgga caccgttacc taaggtactt tgttttgatg
      601 aattcaaatc agttcggggt gtttcaggtg ctatgagttt catcatgatg gatggacaaa
      661 cacagcgctt attggacatt gtcgagaacc gacaactgcc ttttttaaaa cgttatttta
      721 gtcatttttc acgagaaatt cgtgaagcgg tcgaatggat cgtgattgat atgtacgctc
      781 cttatgtatc gctcgttaaa aagctgtttc caaaagcaca gctgattatt gaccggtttc
      841 acatcgtcca acatattggt cgtacctttc gcaatcatcg aatcaaagaa acgaaccaac
      901 tattaaaaag caaagaacaa aaacactatc aattaggtaa gcaattaaaa agatactgga
      961 aacttcttca aaaagatgaa cgcaagcttg attatactcg acgcctttgg cgacctggct
     1021 tcaaagctca tttaacagag accgatattg tggatcgctt actgaaaggg agccctgctt
     1081 tgcgtgtagg ctatcagtta tatcaagact ttctttacgc tgtaaaggaa cgagactacg
     1141 tatcgtttga agaactactt accaataata tcatgcttcc cgaaggctat cagacgacct
     1201 tgagaacgtt ccagaaattt ctgccacaaa tcaaaaatgc tttacaacaa agttattcaa
     1261 atggcccact tgaatgtctg aacaaccata tcaaagtgtt aaaacgaaat gcatatggct
     1321 ttcgtagctt ttataatttc aaattgcgca tcatgattcg tcatggcaac gcattgattt
     1381 tcaactaaaa aagatcaaga ggaactgatc cacttgatct c
//
LOCUS       DAFEIE010000160         1407 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFEIE010000160
VERSION     DAFEIE010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.168"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..218
                     /locus_tag="LP345_002857"
     CDS             <1..218
                     /locus_tag="LP345_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761575.1"
                     /translation="PGINATTTAVATTTANGLMSSTDKTKLDGIAAGAQKNPGNATTT
                     TAGLMSATDKVKLDGLTNITFEKVGTV"
     gene            218..742
                     /locus_tag="LP345_002858"
     CDS             218..742
                     /locus_tag="LP345_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761576.1"
                     /translation="MADIVQLKEDGVAKYLKTHAKGIDGVEGVLVKATGNETVLGTKN
                     FKDGLQFNGLPVQAGMIERAITLADRSDTTNVTDVNGKIIRIGNIVFLTFNFKCGTWP
                     EGSETRWILKIPDGFKRDQGYPAQTALSLVRNASQPADARAFIDQSSIIQAKSGSGSS
                     YISGMWITQDPWPA"
     gene            770..1177
                     /locus_tag="LP345_002859"
     CDS             770..1177
                     /locus_tag="LP345_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761577.1"
                     /translation="MKTIYKVLYPMGYEEHQVEDNFPTSLPFVEVPPILFEKKEDETD
                     EGFGRRQQSQFFNFTENKWEEAVTQDYSKKLELLENLSIGLQVDNAALKKSNEELTEK
                     ADSMAQLNAKLMLNDLTINKKIEAIEKQIGGAS"
     gene            1177..1314
                     /locus_tag="LP345_002860"
     CDS             1177..1314
                     /locus_tag="LP345_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL1761578.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRQFVPLCITDEEADKIISKEESA
                     S"
BASE COUNT          507 a          219 c          309 g          372 t
ORIGIN      
        1 atcctggaat aaatgccaca actacagctg tagctacaac tacagcaaat gggttgatgt
       61 cgtccacaga taaaactaag ttggatggaa ttgcagctgg agcacagaaa aatccaggta
      121 atgctacaac tacgacagca ggtttaatgt cagcaaccga taaagtgaaa ctcgatggat
      181 taaccaatat tacatttgag aaagtgggga cggtttaatg gctgatattg tgcaattaaa
      241 agaagacgga gttgctaagt atttgaaaac tcatgccaaa ggaattgatg gtgtggaggg
      301 tgttttagta aaagccacag gtaatgaaac ggtcttagga acgaaaaatt ttaaagacgg
      361 attgcaattc aatggattgc ctgtgcaagc aggtatgatc gagcgagcta tcacactagc
      421 tgatcgaagt gatacaacaa acgtaactga tgtgaatgga aaaataatca gaatcggaaa
      481 catcgtattt cttactttta attttaaatg tggcacatgg cccgaaggat cagaaactcg
      541 ttggatttta aaaatcccgg acggtttcaa acgtgatcaa ggctatccag cgcaaaccgc
      601 gctttcacta gttagaaatg caagtcagcc agcggatgca cgtgcattca ttgatcaaag
      661 tagcatcata caagccaaat caggttcagg tagttcatat atttcaggta tgtggatcac
      721 tcaagatcct tggccggctt aacagattac taattggagg aagagtaaaa tgaaaacaat
      781 ttataaagta ttgtatccaa tgggatatga agaacatcaa gtagaagata actttccaac
      841 atctttacca tttgtcgaag ttccacctat tttgtttgaa aagaaggaag atgaaacgga
      901 tgaaggtttc ggaagaagac aacagtcgca attctttaac ttcactgaaa ataagtggga
      961 agaagcagtt acacaagatt attcaaaaaa attagaacta ctagaaaatt tatctatagg
     1021 tttacaggta gataatgctg cattgaaaaa atcaaatgaa gagttaacgg aaaaagcaga
     1081 ttcgatggcg cagttgaacg ccaaactgat gcttaatgat ttaacaatta ataaaaaaat
     1141 tgaagcaata gaaaaacaaa ttggaggtgc ttcataatgt ttagttttag cgatgtgaaa
     1201 atgatgtatg attggggctg ttttactgac gatcaagttc gacaattcgt tccactatgc
     1261 attacagacg aagaagcaga taaaatcatt agcaaagaag agagcgcatc ttaattgatg
     1321 tgctttttat tttgattcaa ggagttgtca catgattaat ttaggggaat ggggagcgat
     1381 agcaggatca ataaccgcta tcgtttc
//
LOCUS       DAFEIE010000161         1368 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFEIE010000161
VERSION     DAFEIE010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.169"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            82..>1368
                     /locus_tag="LP345_002861"
     CDS             82..>1368
                     /locus_tag="LP345_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBL1761579.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIN"
BASE COUNT          467 a          263 c          257 g          381 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatcaat
//
LOCUS       DAFEIE010000162         1352 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFEIE010000162
VERSION     DAFEIE010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.170"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            11..1350
                     /locus_tag="LP345_002862"
     CDS             join(11..452,452..1350)
                     /locus_tag="LP345_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBL1761580.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          565 a          175 c          235 g          377 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag agaacgcata tttaaaaaag ttagaaacct tgattcaaga
      481 acaagatttg agcaagaaga aatcaaggtt aaaacaatcc ttcagctcaa aaaagaattt
      541 aaattgaatc tattactttc aattgcacaa ttagcgaagt caacttatta ttactgggta
      601 aaaaaattag ataagccaga taaatatagc aagataaagc aagaaattac agcgattgta
      661 aaagaatcaa gaaactctta tggttatcgt agagtcactt tagcgttaaa gatgaaagga
      721 tatacaatca atcataaaac agttagaaaa ttaatgtccc aaatgggact tacctgtcaa
      781 atccgaataa agcgatataa atcttataaa ggaacagtag gaaaaattgc caagaatgtg
      841 ttaaaacgaa atttttcagt agatacaccc aataaaaaat gggtgacaga cgtcactgaa
      901 ttcaagataa aaggaagaaa aatctatcta tctcctatac ttgatttatt taacggagaa
      961 ataattagtt atagtatatc aactagtcca acatataaac tgattgaaga aatgcttcaa
     1021 caagcaatta aaaaaaaggg aactgagggt tcactgattc tacattcaga tcaaggatgg
     1081 cagtatcaga tgccacaata tcaaaaaaaa ttaaaagaga ataacattat tcaaagcatg
     1141 tctagaaaag gaaattgctt agataattct gtaatagaaa atttttttgg tgtgcttaaa
     1201 tcagagtttt tttatcgaga aaaattccga tcaattgaga tatttcaaag taaattaaat
     1261 gagtatatta ggtggtataa taacaaaagg ataaaactaa agttaaatgg actatctcca
     1321 gtagaatatc ggaaacagtc cattaaatag tt
//
LOCUS       DAFEIE010000163         1350 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFEIE010000163
VERSION     DAFEIE010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.171"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            200..742
                     /locus_tag="LP345_002863"
     CDS             200..742
                     /locus_tag="LP345_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761581.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1347
                     /locus_tag="LP345_002864"
     CDS             898..1347
                     /locus_tag="LP345_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBL1761582.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMAPIALDNEHPRI"
BASE COUNT          540 a          159 c          262 g          389 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tcttgatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgg aatggcaaca
     1261 ctttttttga caaaaattat aaggtgttgt gaatgctgcg gtgttatggc tccgattgcc
     1321 cttgacaatg agcatcctcg gatctgattt
//
LOCUS       DAFEIE010000164         1334 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFEIE010000164
VERSION     DAFEIE010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.172"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            15..1310
                     /locus_tag="LP345_002865"
     CDS             15..1310
                     /locus_tag="LP345_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1761583.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          418 a          264 c          258 g          394 t
ORIGIN      
        1 taggaggatt caagatgtct catactcagc ttatcaaaga taccctaaat attctagacc
       61 taaatatcta tttcgaggaa aattgtttaa ctaaagaaaa atacaaaggg caaatttgct
      121 tgatttacaa aggaactctt ctgtacaagc cagaagagtg ttcccattgt ctttgtgtcg
      181 tcccctctag gatcattcgt tgggggacga caaccgttcg gttgttactg aatgatgtgt
      241 ctgagtatcg cacttatctg gagctgaaga aacaacgatt taaatgtaag tcttgccaaa
      301 gaacattcgt agcggatacc tctgttgctg aaaaacactg tttcattagt caaaaagttc
      361 gttggtctgt cattgctcgc ttaaaagaga atacttccat gacggaaatc gctcgtcaga
      421 aaaatatttc cacttcttcg gtctatcgtg tcatgaagcg attctaccgc ccattgaatc
      481 ctttcaaaca gactttgcca aaggtcttat gctttgatga attcaaatcg gttcgaagtg
      541 ttgccagtgc aatgagtttt atcatgatgg acggacaaag ccatgcatta ttggatattg
      601 tcgaaaatcg acgcttgcct tatttagaac gctatttttc tcggttttca ttagcgactc
      661 gtgaagccgt tcaattgatt gttattgata tgtatgcgcc ttatgtttcg ttggtgaaaa
      721 agcttttccc gaatgctcag ttgatcatcg atcgtttcca catcgtccaa catattggca
      781 gaactttctt gaatcatcga gtgaaagaaa ccacggtacg acttaaagga aattcccact
      841 ctcaacgagg gttagggaaa aaattgaagc gctattggaa actcctacaa aaagaagaag
      901 caaagttaaa ctatgaaaaa cgggtttggc gtgccagttt taaagattat ttgactgaaa
      961 gtgagattgc cgatcgactg ttagctgctt gtcccaactt acgccaaggc tatcagttat
     1021 accaagacat tctttatgcg gtaaagaaaa gagatcagtc actatttgag gattgtttaa
     1081 ctagagacat tagcggtctg ccagaaacct atacaaccac tttacgaacg tttaaaaagt
     1141 ttctgccaca gatccaaaat gcgcttcact acagctattc aaacggacca ttggaatgct
     1201 taaacaacca catcaaagta ttaaaacgca atgcgtacgg ctttcgcaac ttttacaatt
     1261 tcaaactacg aattatgatt cgtcatggca aaacattttt aaccaaataa acagaacaga
     1321 aagaggtttt cttc
//
LOCUS       DAFEIE010000165         1320 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFEIE010000165
VERSION     DAFEIE010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.173"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            59..283
                     /locus_tag="LP345_002866"
     CDS             59..283
                     /locus_tag="LP345_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL1761584.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            280..1305
                     /locus_tag="LP345_002867"
     CDS             280..1305
                     /locus_tag="LP345_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL1761585.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVDGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPQR"
BASE COUNT          456 a          217 c          275 g          372 t
ORIGIN      
        1 cagaaaaatt ggtagaacac acgcaacaaa ttaaaacttt atttagggag agaagaaaat
       61 gaataataaa acgttcgaag tactaaaatg gttcgcactg gtaattattc ccgcactagc
      121 tactttcgtg gggttagttg gtaaagcgct caattggcag tacacagata tctgtgttgt
      181 catcattact ggttttggcg cgtttttagg gagtgtgttg ggtgtatcaa atcgaaccta
      241 caaaatgttc tcggctgaaa gcgaagaagg aggaaacaaa tgaaaaagaa aattactatt
      301 actgcgatga gcctgttaac ggctcttttt ttattaccca ttaatacgtt tgcttatact
      361 attaatgacg agtataattt agcgccgaat caaggagact ccagattagc aattcctaac
      421 aaaattattt tgcacgaaac tggaatagat gcaccagcaa gaaacgtagc cgccaacatg
      481 aaaaataatt ataacggaag caattcttat actacagatg ttattggtga cggtgggatt
      541 gtttaccgtg tgggtgagca aggatatgtt tcgtggggag ctggtaacgc taatccttat
      601 gcgcctgtac agattgaatt acagcgcaca tatgataaag cattgtttga aaaaaactat
      661 cgagcttata ttgaatatac aagagatagt gcaaaaaaat atggaattcc attgactctt
      721 gatcaaggaa cttctttatt tacaaaagga atcatttctc atttgtgggt gacaaattat
      781 gtttggggga accacacaga tccatatggt tacttatcgc aaatgggagt tagcaaagaa
      841 aagcttgctt atgatttagc tcatggattt accgatgaaa atccaactac ttcagatgat
      901 aaaccagtca ttgatccaac tagagcaggt gcagcaaatc ctacgctgac agatggaaca
      961 aatcacgccc acattgatca gtttggagaa atcgaaaacg caaacttgca tgtggatgga
     1021 tggcacattg ctaattataa atacgagtat attttcatta tggattacaa tactggaaaa
     1081 gaattagctc gagtaagagc tgatggaatt tatagaccag atgtaaatca agcttataat
     1141 acttctggaa acgttggtta tcatgtatct ttcaatatgc gtaattttcc taataagaaa
     1201 gtctatgtaa tgatgcgtgc aacgaatgat ccagaaggga acactaaagg cggagcacaa
     1261 gattttcatg ataaacgctg gtatttaaat attccgcaac gataaaaaaa gcccctcgat
//
LOCUS       DAFEIE010000166         1310 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFEIE010000166
VERSION     DAFEIE010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.174"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1095)
                     /locus_tag="LP345_002868"
     rRNA            complement(<1..1095)
                     /locus_tag="LP345_002868"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          291 a          366 c          251 g          402 t
ORIGIN      
        1 cctagttgtc tgtgcaaccc cacatccttt tccacttaac atatattttg ggaccttagc
       61 tggtggtctg ggctgtttcc ctttcgacta tggatcttat cactcacagt ctgactcccg
      121 gatatgaatg aatggcattc ggagtttatc tgaattcggt aacccgagat gggcccctag
      181 tccaaacagt gctctacctc catcattctc aattccgagg ctagccctaa agctatttcg
      241 gagagaacca gctatctcca agttcgtttg gaatttctcc gctacccaca cctcatcccc
      301 gcacttttca acgtacgtgg gttcggtcct ccagtgcgtt ttaccgcacc ttcaacctgg
      361 acatgggtag atcacatggt ttcgggtcta cgactacata ctcaaacgcc ctattcagac
      421 tcgctttcgc tgcggctccg tctcttcaac ttaacctcgc atgcaatcgt aactcgccgg
      481 ttcattctac aaaaggcacg ccatcaccca ttaacgggct ttgacttgtt gtaggcacac
      541 ggtttcaggt tctatttcac tccccttccg gggtgctttt cacctttccc tcacggtact
      601 ggttcactat cggtcactag ggagtattta gccttgggag atggtcctcc cggattccga
      661 cggaatttct cgtgttccgc cgtactcagg atcctcctag gtgtcttcca catttcgtct
      721 acggggtttt taccctcttt gactgacttt tccaagtcat tcgactatct gaaagaacta
      781 ccatattgga gtcctacaac cccaacaagc aagcttgctg gtttgggctt ttcccgtttc
      841 gctcgccgct actcagggaa tcgaattttc tttctcttcc tgcaggtact tagatgtttc
      901 agttctctgc gtctacctcg aatgtgctat gtattcacac aatcgtaaca tcctattaaa
      961 gatgttgggt tcccccattc ggaaatctct ggatcatagc ttacgtacag ctccccaaag
     1021 catatcggtg ttagtcccgt ccttcatcgg ctcctagtgc caaggcatcc accgtgcgcc
     1081 cttattcact taaccttatc aaccttgcgg ttgggttttg atccttcttc tagcgataga
     1141 agttagatca agaaaataag caattgaact tattaaaaaa ctctatccag ctcacaaatc
     1201 agcctgtgcg gcaaaaagat cgatcgtctc ataaaatcaa agattttata gccgtccgcc
     1261 tattttgctt taggctaaac aatttgttca gctttcaaat tcaacgcggt
//
LOCUS       DAFEIE010000167         1260 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFEIE010000167
VERSION     DAFEIE010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.175"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..252
                     /locus_tag="LP345_002869"
     CDS             <1..252
                     /locus_tag="LP345_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761586.1"
                     /translation="FNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDKTKLDGIAA
                     GAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            252..746
                     /locus_tag="LP345_002870"
     CDS             252..746
                     /locus_tag="LP345_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761587.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            760..1191
                     /locus_tag="LP345_002871"
     CDS             760..1191
                     /locus_tag="LP345_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761588.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            1193..>1260
                     /locus_tag="LP345_002872"
     CDS             1193..>1260
                     /locus_tag="LP345_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL1761589.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMV"
BASE COUNT          469 a          184 c          274 g          333 t
ORIGIN      
        1 tttaattttg ttttaccaaa gggagataaa ggtgatcctg gaataaatgc cacaactaca
       61 gctgtagcta caactacagc aaatgggttg atgtcgtcca cagataaaac taagttggat
      121 ggaattgcag ctggagcaca gaaaaatcca ggtaatgcta caactacgac agcaggttta
      181 atgtcagcaa ccgataaagt gaaacttgat ggattagcga atattacatt tgagaaagtg
      241 gggacggttt aatggctgat attgttcaat taaaagaaga cggagttgct aaatacttaa
      301 aaacgcatgt agaagctatt gatggtaaag aagcattggt gcagacagat ggagaccaag
      361 ccattgcagg acataagaat ttttcaggtt ctgtaacaat caataataaa cgtgttttga
      421 cgactgatga taacagatat gaagtggtaa atctggttgt cactaacggt aatacaggga
      481 cagcaaagct ttatcgtgaa ggaaaaacag tttctatata ttttgtggct ttaaacggaa
      541 aaagtagtgg cgggaatgat tcggttattt taactgttcc agaaggctat cggacaccaa
      601 ttagttttga acaactggtt gggtcaatag accgttctac tttgaacagt gctcaactat
      661 ctattggcgc agacggagcc attaaatgga gaagaaattc aagttatgga tcagcttatt
      721 catttgttat cacttattca atttaaggga ggaaatctaa tgaaagtagt ttacaaatca
      781 atcaagcctt acggattcga gcaaatcatt ttgaacaatc aagaaaatat ccctgaaaac
      841 tgtacagaga ttaaaccacc agttcctaac tggagaccaa gatttgattt tgataaaaaa
      901 cagtgggttg agttagctac tgaagaagag aaaaaaggga atgctgttga tagcgtagat
      961 gaattggcta atattaaggc attatacgaa acgctgaagg cagaaaatga tgaattgaaa
     1021 cagctaaatt ctaaagcaat gctaaacaat gtagcaatca agcaagaaaa tgtcttattg
     1081 aaagaaaagt cagaaagttt agcgcagttg aattcaaaaa cgatgcttgc ttctgtacaa
     1141 aataccaagg aaatcgaaga aatcaaaaaa caattacaag gtgggaagta acatgtattc
     1201 atatgaagat atcaaactaa tgtatgactg gggctgtttc actaacgaac aagtaatggt
//
LOCUS       DAFEIE010000168         1258 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFEIE010000168
VERSION     DAFEIE010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.176"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1171)
                     /locus_tag="LP345_002873"
     CDS             complement(<1..1171)
                     /locus_tag="LP345_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBL1761590.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEF"
BASE COUNT          367 a          273 c          211 g          407 t
ORIGIN      
        1 taaattctaa atattttcgt ggagaagcca gccactcagt gtctttttcc atcaaaagtg
       61 ttccaattat ccgagtgatg gaattgatat ttggaaaaat ccgaatcact cgttctctcc
      121 ggcgaatctc ttcgttcaac cgttccaaca cattggttgt acgaatcctt cggcggatat
      181 tttcaggaaa agacaaaatt tgaatagcat cttcaaagcc gttttctaaa atgtcgcaag
      241 cagcacttaa ttttgaatca caaccatatt tttccaagaa gtgctctttt ctttcacgtg
      301 tcaattcaag ttcagaggct ttaaagatac tcttcaactc gtcttttaca tcagaagaaa
      361 ctttctttgg cagcttatca aaaatatttc tcaaaaagtg ggcttggcat ctttgccagc
      421 tcgcacctaa aaagttcttg cgaacagcct taactaaccc tttgtgtgca tcagaaatga
      481 ccagttttac accgaacaaa cctcgttgaa cgaacgattg aaaaacggta tcccaattat
      541 cttccgattc gccgtcttga acatcaaaac caagaatcgt acgtcgtcca tcagaatcaa
      601 tgccgatacc aatatataca ccttttgaga caatacgatg attttccctt actttcatat
      661 acagggcatc acacatgaaa aatggatatt ccgagccttc taggctccgg tttctccact
      721 caaaaacaaa tggatccaac tgtttcatca gatttgaaac gaatgattta gaaacagtcg
      781 caccatccgt tagcagttca actgttttag ttactttgcg agtggagaca ccagaaatga
      841 ccatttcaat catggcagcg atcaaagctt tttcgcttcg ctgatatctt tcaaagatag
      901 taggactaaa cttaccgtct ctggttcgtg gaacatgaag ttctaacgta ccaattcgag
      961 ttgtaaacga acgatcgtag taaccatttc tttgtgattg ccgttcttct gaacgttcat
     1021 aggcatttgc ctgaatatat tgatttcgtt gttcttccat cagctgatta aacatgatag
     1081 tcataagtgt ttttgcggta tcattcgcac cgctttcgtt tataattgct tgaatttctt
     1141 cgctttcaaa agtaaaatgt acttgagtca ttgatatcag tcctattcga gtatgttttc
     1201 tgcaaaaaac attgtactcc taactgagat caatggcttt tttgatgctt cactttta
//
LOCUS       DAFEIE010000169         1193 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFEIE010000169
VERSION     DAFEIE010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.177"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..1076
                     /locus_tag="LP345_002874"
     CDS             <1..1076
                     /locus_tag="LP345_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL1761591.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DAFEIE010000170         1188 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFEIE010000170
VERSION     DAFEIE010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.178"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            141..398
                     /locus_tag="LP345_002875"
     CDS             141..398
                     /locus_tag="LP345_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761592.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="LP345_002876"
     CDS             complement(630..1061)
                     /locus_tag="LP345_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBL1761593.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DAFEIE010000171         1187 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFEIE010000171
VERSION     DAFEIE010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1187
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.179"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            14..1141
                     /locus_tag="LP345_002877"
     CDS             14..1141
                     /locus_tag="LP345_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1761594.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          426 a          209 c          232 g          320 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa ccaccggtgg caaaccggtg gcaaatc
//
LOCUS       DAFEIE010000172         1134 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFEIE010000172
VERSION     DAFEIE010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.180"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            55..>1134
                     /locus_tag="LP345_002878"
     CDS             join(55..331,331..>1134)
                     /locus_tag="LP345_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL1761595.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANK
                     HLYPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSK
                     RGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIV
                     TDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFH
                     TDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQ
                     QLDLELFDYVNWWNHLRLHGTLGYET"
BASE COUNT          425 a          192 c          217 g          300 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
      241 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
      301 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
      361 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
      421 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
      481 tccgcagccg aaaggcctac ggctcaagaa aaataaaaaa agccttatca aaacgaggca
      541 ttcagatcag ccgacgaaaa attagtagaa tcatgaaaaa tagaggatta aaatcgagct
      601 atactgttgc ttattttaaa gtacatcatt ctacttgcaa tgaagccaaa acgacaaacg
      661 tattgaatcg taaattctta agagacaacc cattagaagc gatcgtaaca gacttgactt
      721 atgtacgagt cgggaaaaaa tggaattatg tctgtttcat tttggatctg ttcaatcgag
      781 aaattctcgg ctattcttgt ggagaacata aagatgccgt tctagtaaaa aaagcattta
      841 gccgtatcaa acaacctctg acagaggttg agatttttca tactgatcgt ggaaaagagt
      901 ttgataacca agctattgat gaattattaa caacttttga catcaatcga tcattgagtc
      961 ataaaggctg tccttttgat aatgccgtag ctgaatcaac ttataagtcg ttgaaagtag
     1021 aatttgtcta tcaatacaca tttgaaacct tacaacaatt ggatttggag ttatttgact
     1081 atgtcaattg gtggaaccac cttcggttgc acggtacact tggctacgag acac
//
LOCUS       DAFEIE010000173         1091 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFEIE010000173
VERSION     DAFEIE010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.181"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="LP345_002879"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="LP345_002879"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBL1761596.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DAFEIE010000174         1061 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFEIE010000174
VERSION     DAFEIE010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.182"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(36..992)
                     /locus_tag="LP345_002880"
     CDS             complement(36..992)
                     /locus_tag="LP345_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761597.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DAFEIE010000175         1005 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFEIE010000175
VERSION     DAFEIE010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.183"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            500..>1005
                     /locus_tag="LP345_002881"
     CDS             500..>1005
                     /locus_tag="LP345_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1D family transposase"
                     /protein_id="HBL1761598.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQ"
BASE COUNT          348 a          159 c          182 g          316 t
ORIGIN      
        1 acacaaaatt attgacgctc ccaagctaaa actcctatta atcgatctac taaaaataaa
       61 taaaaaaatt cttttcaatt ttatttatgg tatgacataa ataaagtaaa gttattcttc
      121 taggttaatc ttattaatac tctttctcac tagtgttgca tgcaacacta gtgagaaaga
      181 gtattaaata tactgcaagg caagacattt ggtaattgaa gaataacaag caaaaaaata
      241 gcagtcaggt ctcttgacaa agtatagttg ctattctttt tttaggccct actttaatga
      301 aatttttgtt tggagggaac gacttcattc ctttgattat ttcagttgaa tttaatagag
      361 aagcctggcg tctattaaga aatacttttc ttgatgagcg tcaatttttt taacggaaat
      421 ctatccggtt ctgttgcaaa gttttccaaa aaatctattt tagtgtaaaa ttgagaaaaa
      481 agacagagag gacagagtaa tgaatcattt taaaggcaaa caattcaaaa aagacgtcat
      541 tattgtcgct gttggttact acctgcgtta caatctaagc tatcgtgaag ttcaggaatt
      601 gttatatgat cgtggaataa atgtttgtca tactacgatt tatcgttggg tgcaagagta
      661 cagcaaagtc ctctattatc tttggaagaa gaaaaataga caatccttct attcatggaa
      721 aatggacgaa acctatatca aaattaaggg acgttggcat tatctttatc gtgcaattga
      781 tgcggacggc ttaaccttag atatctggtt acgaaagaaa cgggatacgc aagcagccta
      841 tgctttctta aaacgactcc ataaacagtt tggtgagccg aaagcaattg tgaccgataa
      901 agcaccttct cttggctccg cctttagaaa gttacagagt gtgggtttat atactaagac
      961 agagcaccga actgtgaagt atcttaacaa tttaatagaa caaga
//
LOCUS       DAFEIE010000176         1002 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFEIE010000176
VERSION     DAFEIE010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.184"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            52..307
                     /locus_tag="LP345_002882"
                     /pseudo
     CDS             52..307
                     /locus_tag="LP345_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752209.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            371..1002
                     /locus_tag="LP345_002883"
                     /pseudo
     CDS             371..1002
                     /locus_tag="LP345_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          344 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaaaa
      301 tataggctct ataatttatg ggactgatga atcaaaattg attcttcagt cccattgtta
      361 ttttaggtat atgattcgta cattgaaaga gttgaaaaac tatcttccga agccgtcaaa
      421 aaggaccctg ccaaaagtat tgatggtgga tgaatttcgt tcgcacgctt caattgtgga
      481 taaaatgagc tttatttgtg cggatggcga gactggaaaa ctcattgata ttttgcctac
      541 acgaaaattg tctcgattaa cacactattt tagtcgctgt gcaaatcctg aagcggtgga
      601 atatttagtg acagatatga acgccgccta cttccaactg acaaaacgtg tcttaccaaa
      661 tgcgaaagtc gtcattgatt gttttcatat catcaaacat ttgaatcagg cgttcaatga
      721 ttttcgtgta caagaaatga aaagattaca ccagttaggg caacgacggg aagccgagaa
      781 agtgaaaaag aactggcgct ttcttctaaa aaaccgtcaa aaaatcaatc actatgatta
      841 caaaacatgg cgcagttttc gtgcacctaa atacccgcta ctcactgaag caatgatgat
      901 tgatcgattg ctggcatttt caacgccttt aaaggacgcc tatacttttt tccatgagct
      961 gaccgaagcc tttagagaca aggaatcaga cttatttttt ac
//
LOCUS       DAFEIE010000177          908 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFEIE010000177
VERSION     DAFEIE010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.185"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..750
                     /locus_tag="LP345_002884"
     CDS             <1..750
                     /locus_tag="LP345_002884"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL1761599.1"
                     /translation="SIYIASESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNE
                     VWTWDITWLKGPIKGLFYRLYLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERI
                     QGQPLVLHSDNGSPMKAATFQVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEY
                     PNNGFKTIDDARKWTKEFVDWYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDA
                     KKRHPERWSKGVRNWTPHQSVALNPLKETES"
BASE COUNT          300 a          179 c          192 g          237 t
ORIGIN      
        1 tcgatttata ttgcatcaga gtctagcttc tatcgtgtat tgcgagaaaa aaatatgcaa
       61 catcaccgtg gccgaagtca agtttcacaa aaacgcatac cgccaagtca ccttgcgacg
      121 aagccaaatg aagtttggac ttgggatatt acttggctaa aaggtccaat aaaaggactc
      181 ttttaccggt tatatctcat cattgattta tttagccgta aaatggtagg ctgggagatt
      241 tgggaatcag aagaagctcg tcatgccgaa aaacttatta aacagacggt gcttaaggaa
      301 cgtatccaag gacagccgtt ggttttacac tccgataatg gcagccctat gaaagccgcg
      361 acttttcaag tcttactcga aaaattagga attcaaagtt cttattcaag accacgagtg
      421 agtaatgaca atccttattc ggaagcggct ttccgaacgt taaaatatcg accagaatat
      481 cccaataacg gctttaaaac aatagatgat gctcgaaaat ggacgaaaga gtttgtcgat
      541 tggtataacg attctcattt gcatagtggg attcaatttg tgtctcctgc agcgtgtcat
      601 gaaggacgac atctcgctat tttagagaaa cgaaagcagg tttacgagga cgctaaaaag
      661 cgccatcctg aacgctggtc aaaaggtgtt cgaaattgga ctccacatca atcggtggcg
      721 ttgaatcctt taaaagaaac agaaagttaa caggagcata atctttcaag attatcaaat
      781 aaccctcgtc acccaatagg ggaaaaagtt attcttcccc tattggataa cgaggccaac
      841 cgaccatagg gaggttctgc tttttgatag gtggaaaata aaaatacgac aactatattg
      901 acaaacac
//
LOCUS       DAFEIE010000178          891 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFEIE010000178
VERSION     DAFEIE010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.186"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..>891
                     /locus_tag="LP345_002885"
     CDS             <1..>891
                     /locus_tag="LP345_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBL1761600.1"
                     /translation="PRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDT
                     PYITEGEYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMT
                     AAAFEQLSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGW
                     KKLFGKESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAG
                     KTVDSEEAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVE
                     KEPLLTSAEMTAKWESYLLKI"
BASE COUNT          335 a          169 c          195 g          192 t
ORIGIN      
        1 ccacgtcttt tttctctatc cagccttcaa tctaaaatga atcagctcat gaaagctagt
       61 gccaaagata ctttggaagc catgcaaggg ttgtatgaag ggaaatatct aagctaccca
      121 cgaacagata ccccttatat tacagaaggg gagtatgcgt atctgttgga tcacttagac
      181 gaatacaaac actttttaaa ggccgaagcc attcctactc ctattcatac accgaatagt
      241 cgatatgtga ataataagaa agtccaggaa cattacgcga tcattcctac aaagacggtc
      301 atgacggcag cggcttttga acaattaagt ccactgcagc aggctattta tgaacaagtg
      361 ttaaaaacaa cggtggccat gtttgcggaa aagtatacct atgaagaaac aacgatcttg
      421 acgcaagttc agcagcttca gctaaagaca gtcggaaaag taccagtaga tctaggttgg
      481 aaaaagctgt ttggcaaaga gagcgacaga aaagaaaagg aagaagaacc gctacttcct
      541 aaagtgacaa aaggagaagc ggtgacggta gatctacaag tccttgaaaa agaaacgaag
      601 ccaccacaac cttataccga aggtacgttg atcacagcga tgaaaacagc tggaaaaacc
      661 gtggatagcg aagaagcaca atccatattg aaagaagtag aaggaatcgg tacagaagca
      721 acacgagcaa atattattga aactttgaaa caaaaggaat atatcaaggt agaaaaaaat
      781 aagcttgtgg tgacaaataa agggatttta ctttgccaag ccgtggaaaa agagccgctg
      841 ctaacaagtg ccgaaatgac cgccaaatgg gaaagttact tattaaagat t
//
LOCUS       DAFEIE010000179          865 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFEIE010000179
VERSION     DAFEIE010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.187"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            136..822
                     /gene="gpmA"
                     /locus_tag="LP345_002886"
     CDS             136..822
                     /gene="gpmA"
                     /locus_tag="LP345_002886"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL1761601.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
BASE COUNT          308 a          163 c          156 g          238 t
ORIGIN      
        1 ttttttatat tctctacttg ttttctcata gaatcttatc taatttttcg atggaaatct
       61 cttccaaaaa attgtacaat aaaacagaac tgaaaatttc agaaatataa acctatctta
      121 aaaggagagc taaacatgcc aaaattagtt ttttctcgtc acggtcttag tgaatggaat
      181 gcattgaacc aatttactgg ttgggctgat gtaaatctag caccagaagg aatcgaagaa
      241 gcaaaagaag gcggacgcaa aatcaaagaa gctggaatcg aatttgatgt tgcttacact
      301 tctgttttaa ctcgtgcaat caaaacatgt aacttgatct tagaatattc agatcaactt
      361 tgggtaccac aaatcaaatc atggcgctta aacgaacgtc actatggtaa attacaaggt
      421 ttgaacaaaa aagaaacagc tgaaaaatac ggcgacgaac aagtgcacat ctggcgtcgt
      481 tcttacgata ctcttcctcc attaatggaa gaaactgacg aaggttctgc agcaaatgac
      541 cgtcgttacg caatgttaga caaacgcgat attcctggtg gagaaaactt gaaagtgaca
      601 ttagaacgcg ctttgccatt ctggcaagat gaaattgctc cagcattact agacaacaaa
      661 actgttttag tagctgcaca tggtaactca ttacgcgccc tagctaaaca tatcgaaggt
      721 atctctgacg aagacatcat ggatcttgaa attccaacag gtcaaccact tgtttatgaa
      781 ttaaatgatg acttaacagt tgctaaaaaa tactacctat aaaaaacact ataaaaaagg
      841 gactgtgaca cgatttgtca cagtc
//
LOCUS       DAFEIE010000180          860 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFEIE010000180
VERSION     DAFEIE010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.188"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            555..>860
                     /locus_tag="LP345_002887"
     CDS             555..>860
                     /locus_tag="LP345_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1761602.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     "
BASE COUNT          309 a          163 c          139 g          249 t
ORIGIN      
        1 agacactcct cttaatatac agtcctattg tataaagtgt tactatatac atagtaactg
       61 tatacataaa aaaagtcaag tattagaaaa aagttcaaaa gatcaagtgt gcgcttcgct
      121 cccactcccc tcgacgtttt agtagccttt ccctcacttc gttcagtcca agccaactaa
      181 aaagttttcg ggatacattc tccttctctt cctaataatc aattaaaatt ttaatcttta
      241 tatttctgct aatcactcag gaaacagtac agaaaaacaa acacgtatca tagatataaa
      301 tgtaatggca tagtgcgggt tttattttca gcctgtatca tagctaaaca aatcgagttg
      361 tgtgtccgtt tttgggcgtt ctgctagctt gtttaaagtc tcttgaatga atgtatgttc
      421 taagtcaaaa aactctgaca gcgcctttat atagataaag tccgtataat tgtgtaaaag
      481 taaaaaggcc atataacagt ccttttacgg tacaatgttt ttaacgacaa aaacataccc
      541 aggaggactt ttacatgacc caagtacatt ttacactgaa aagcgaagag attcaaagca
      601 ttattgaata ttctgtaaag gatgacgttt ctaaaaatat tttaacaacg gtatttaatc
      661 aactaatgga aaatcaacga acagaatata ttcaagcaaa agaatatgaa cgaacagaaa
      721 accgacaaag tcaacgaaat ggctattatg agcgcagctt tacgacacgt gtaggcacgc
      781 tagaattaaa agtacccaga acacgtgatg gccatttttc acccacagtg tttgaacgtt
      841 atcaacgaaa cgaaaaagcc
//
LOCUS       DAFEIE010000181          852 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFEIE010000181
VERSION     DAFEIE010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.189"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(1..152)
                     /locus_tag="LP345_002888"
                     /pseudo
     CDS             complement(1..152)
                     /locus_tag="LP345_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(429..626)
                     /locus_tag="LP345_002889"
     CDS             complement(429..626)
                     /locus_tag="LP345_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1761603.1"
                     /translation="MNNGTVKWFNSDKGFGFITGEDGNDVFAHFSAIQGEGFKSLDEG
                     QAVTYDIEEGQRGPQAVNIVK"
BASE COUNT          284 a          159 c          116 g          293 t
ORIGIN      
        1 gtgatgacgg cacttttatg gtggatgccg acaatcgtat caccctctaa atgtccaaat
       61 tcttcttcga aaacgacata atctttttta cgctcagaaa tatttctttt gaatgcctgt
      121 tttccacgtt tttccttata accatttcat tgtgatccac ctcttttgtt tattagttta
      181 aaccatcaaa ccatttttaa taaaatatgt aaattccttt gctcaaaaaa gtagcttctt
      241 tacgattcga caatttcaaa taaagcaggt aaaaactggc tgtcagaaaa tagccaaact
      301 gaagcaaaaa ataatgttaa aattaattaa tgaacgaaaa aaatccctca cctaatatta
      361 cggtgaggaa ttttttctac cgacataaac aaaaaaacca cctcatatga ggcggttaac
      421 gttcaacatt attttacgat atttactgct tgaggaccac gttgtccttc ttcaatatca
      481 taagtaactg cttggccttc atctaaagac ttaaagcctt ctccttggat tgctgagaaa
      541 tgagcgaata cgtcatttcc atcttcacca gtgatgaaac caaaaccttt atctgagtta
      601 aaccatttta ctgtaccgtt attcatatat atttcctcct gatacgtata taatacgtgt
      661 tttattgcaa ttaatattac ttggtaaaag gagtttttat agtgtgaata tatcgctcag
      721 attacgtttc aaattagatt acttatttac tataacacgg atgtaatgct aacacaagga
      781 taatcactcg atatacggtt taaatattat tatttgtcaa attaagcgag acaaaacttt
      841 ccatttacgt aa
//
LOCUS       DAFEIE010000182          828 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFEIE010000182
VERSION     DAFEIE010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.190"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(78..578)
                     /locus_tag="LP345_002890"
     CDS             complement(78..578)
                     /locus_tag="LP345_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL1761604.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
BASE COUNT          313 a          146 c          140 g          229 t
ORIGIN      
        1 aataaagcgt gcagtctgtt gagactgcac gctttattgt ttaatccaaa atcagtttac
       61 taccttagta cgtaaaatca aacagctcgt ttaaacactt ttctagcctc taaagttttg
      121 ataaatgaat aaacaaccat tatttgaata gggatttgga tcatattcct gatgaatcta
      181 cctagaaaaa ttactttgaa atctgcacca aacaaaacag acatcagcca agaattgata
      241 aaaaggctga ctgggatcat aatcaataat tgggcagcga tgacggaagg caggtttatc
      301 tttttatgat ataaaaataa gccattaata aatccaccaa ggaaagccgt gataagaaaa
      361 gcagcttgaa acgttcctga accaaatatc gtgaaattta aagtgttcga caacatttca
      421 agcaaaccag cccagatcgg tccatataga taacccataa gcgccatact taaaaatccg
      481 aatgtgattt gaaaataagc aggaccaatc gctatcttgt ataagatgac atcaagggct
      541 aataaaagag cagaggtcga caacaatctt gcattcattt cgggcaatct aaaaacgtct
      601 tttgcaatca aagtgttcaa aatattctct cctttgtcag ttaataataa aaggatacca
      661 taaaatcacc aatgtgtcat gacacattgg tgatttacat acactggcat ctaacaatta
      721 aaaaaagggt gagaagactg cttttataaa ctgtaaaaaa gagattgtac gaataaaaaa
      781 aatagaggcg gagaatactt atcgtatcat ccgcctttgt ttttttgt
//
LOCUS       DAFEIE010000183          791 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFEIE010000183
VERSION     DAFEIE010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.191"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..782
                     /locus_tag="LP345_002891"
     CDS             <1..782
                     /locus_tag="LP345_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1761605.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DAFEIE010000184          789 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFEIE010000184
VERSION     DAFEIE010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.192"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            23..>789
                     /locus_tag="LP345_002892"
     CDS             23..>789
                     /locus_tag="LP345_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBL1761606.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSR"
BASE COUNT          282 a          147 c          136 g          224 t
ORIGIN      
        1 tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc aaactctagt
       61 cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga taaacacact
      121 cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca ctggttttaa
      181 ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat atggtgaatt
      241 aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt taccagccta
      301 caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa aaggtgttac
      361 gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata ctccacaaac
      421 catgtccaac atgactaaag ttctgactga agaagtaaat gcctttaaat ccagagcctt
      481 aaatgataag tatgtcgcta tttttatgga cgctacttac attccactaa aacgtcaaac
      541 cgtatccaaa gaagcgattt atattgccat tggtatacga gaagacggca ctaaagaagt
      601 actgagttat gcgattgctc caactgaatc aacatacgtt tggaatgagc tgctacagga
      661 tattaactcc agaggagttc aagaagtctt gctttttatt acggacggct taaaaggcat
      721 gaaagatact atccatcaaa tttatcctaa agcaaaatat cagcattgtt gtatccatgt
      781 atctcgtaa
//
LOCUS       DAFEIE010000185          775 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFEIE010000185
VERSION     DAFEIE010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.193"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(249..728)
                     /locus_tag="LP345_002893"
     CDS             complement(249..728)
                     /locus_tag="LP345_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761607.1"
                     /translation="MCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNSL
                     DFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKCFESAVVKFPQFKLNP
                     AASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          262 a          106 c           87 g          320 t
ORIGIN      
        1 tgacgctccc ttaacaataa atgaagactt ttttattgtt aattgtttat ttttctatta
       61 ttagatatga aaatcgcatt tagataaaat agaaaaatat gaatatattt taaatattaa
      121 gatgagagtc attaacttat gatagtagtc aatttgcttt tcactaatta caaaatatgt
      181 gatataggaa gtttagttat tgttctcata atgccatcct gtttttagat tatctagtaa
      241 tttttttgtt atttaaaatt aggagcagtg ccaattgttt taattttaaa ggcttttttt
      301 atatcttcta aattagaaga tatttgtata tcaatatgga atatattacc ttttttgtat
      361 ttttttatgt tatctttagc taaaacatca aatacatgtc cttgaaattg tatcgaggca
      421 gctggattta gtttaaattg aggaaacttt accacagctg attcaaaaca cttgtcacat
      481 ttttttattt ttttaccttt gtaaaaatat tcgattgaat attctatttg gcacgactca
      541 cttggcagta tatgtatgtc aatatttttc atctgtttca taggtatttc aaaatctaaa
      601 ctattaaaaa catataattc cctgtaatta tttacatcta actctactaa atttatcttt
      661 ggaacaatag atcctccacc cattccacca taataaaaaa aatcttgttc tctatcaaaa
      721 tagcacatat taagctcagt ttgtttatca tcctcaataa ttttataaat caaac
//
LOCUS       DAFEIE010000186          750 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFEIE010000186
VERSION     DAFEIE010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.194"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..>750
                     /locus_tag="LP345_002894"
     CDS             <1..>750
                     /locus_tag="LP345_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HBL1761608.1"
                     /translation="TFKEIMRTVSNIYHNCVPDKIKNRRNTDQLKQRDTVIIACVIWG
                     IINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGEL
                     VGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYS
                     ITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSE
                     KLDHSLLGKQRKTVETVFSSLEKLGCQNFNS"
BASE COUNT          266 a          139 c          127 g          218 t
ORIGIN      
        1 taacattcaa ggaaattatg agaactgttt ctaacatata ccacaattgt gtaccagata
       61 agattaaaaa ccgaagaaat actgatcaac tgaagcaacg cgatacagtg attattgctt
      121 gtgttatatg gggcataatt aatggctata ctagccaaag agccacgtat agagcggttt
      181 gttccgtctt atttcctaat ggtgactttc ctagtaggag tcgattcact cgcttaagtt
      241 caaacttagc ttacactatc aagattattc gatacttttt catcaagaag ctcaccaaag
      301 gtgaactagt cggaattata gatagttttc ctagtccatt atgtaaacca gttagaaata
      361 gacaagcaaa actattgaat caaatagcca aagttggcta taactcaaca aaaaaatctt
      421 atttttatgg tcttaaaatt catatgatcg ttactaagac tggctttccg attacttact
      481 caatcacgaa tccaggtgtc catgacgtga aagtgttaga gactttatcg gaagaagcga
      541 atcttcccaa tatcctaggg gacaaaggat atattagcca taaaatccat gaaaagcttg
      601 cccttaaggg cattactata tccgttccgc cacgtaaaaa catggataaa tcagaaaaac
      661 tagaccacag cttacttgga aaacaaagaa aaacagttga gactgttttt tcttccttag
      721 aaaaattagg ttgtcaaaat ttcaactcac
//
LOCUS       DAFEIE010000187          698 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFEIE010000187
VERSION     DAFEIE010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.195"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
BASE COUNT          247 a          116 c           85 g          250 t
ORIGIN      
        1 ccaaattact tcatcaaaac attgatataa tttttattat atcagtattt attcttgata
       61 cataaatgag aaaataaata ctttaaatct attgactaca agtagtcatt aagtcttcat
      121 aagatgtaca atatgacatt aaaaaaataa aagcttacga ccatccgtta aatctgacac
      181 taaataatgg actgctttct tttgtattag caggttacgt tgactatgaa tattcaccag
      241 attatttgga gaaacctctt caacacgaga acaatgatat taattttaga tttgtctacg
      301 agtcaaaaag taaaacatgg ttagttgatc aattaagcac gataaacaca agcttccatg
      361 aattacctaa acctgaaaat gaagttgaga tggtcattaa aatcttctaa aaaagaagcg
      421 ttgaagggga aatattcctt tcaacgctct tttttatatg cttagaaaca taaataaatt
      481 gtatactttc tttttagccc ctattacttt tcacgaaaaa tatctttttt tcgacgctag
      541 cgtttctcta cttctaatac tgtacacagt ttttgtatta ttgaaaaatt actcattatt
      601 tagcattaat ccacatcgtt ttatcaatcg accttcatac taaactactt taaagtcatc
      661 ttccttctcg tttttcatta atggaatggc aacagttt
//
LOCUS       DAFEIE010000188          652 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFEIE010000188
VERSION     DAFEIE010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.196"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(537..652)
                     /locus_tag="LP345_002895"
                     /pseudo
     CDS             complement(537..652)
                     /locus_tag="LP345_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611995.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          218 a          120 c           99 g          215 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttccat acggatcgtg gaaaagaatt tgataaccaa accattcaga
      541 atctcatgaa tggtttggtt atcaaattcc tttccacggt ctgtatgaaa aagcttgacg
      601 tctgttaaag aatacggtat ccgtccaaag gcttctttta ccaatgaggc at
//
LOCUS       DAFEIE010000189          637 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFEIE010000189
VERSION     DAFEIE010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.197"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..>637
                     /locus_tag="LP345_002896"
     rRNA            <1..>637
                     /locus_tag="LP345_002896"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          183 a          140 c          184 g          130 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccact
//
LOCUS       DAFEIE010000190          615 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFEIE010000190
VERSION     DAFEIE010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.198"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            75..>615
                     /locus_tag="LP345_002897"
     CDS             75..>615
                     /locus_tag="LP345_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761609.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQ"
BASE COUNT          215 a           78 c          138 g          184 t
ORIGIN      
        1 ggagctttga ttattgcaac tgttgatgat ccaaaacaga atgttttcac tcttgagaaa
       61 gttggggtga tttgatggtt aaagtaaaga gaatgatgga gactgatgaa tctggtgtta
      121 aacgtcaatt tatgccaatt acacatgttt ctgcagtttt aggcttagaa aaaatgatat
      181 caggacaatc aaaagttctt tcggttaatg gtaaatatgg tgcagtcatt ttaacgaaag
      241 ctgatttagg attagagaat gcaattactg aactacctta tgcaagcgag acaagcgatg
      301 gtattcttac tgctgaaatg tttcaaaaga tcgtaaatgg agaaggtgga acatatattt
      361 tgccgattgc tactcctgaa caattaggag gtataaaagt tggggaactc ttagaagtta
      421 ctgaagaagg tgttttatct gcaactaagc aaacagactt caatttctct gaagaattaa
      481 agggaaaatt agaatctcta aaaatattaa aagcaggtgc aaatatatca attgcagaag
      541 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgttaatcag tcatatgtag
      601 atcaaaaatt ccaag
//
LOCUS       DAFEIE010000191          610 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFEIE010000191
VERSION     DAFEIE010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.199"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..>610
                     /locus_tag="LP345_002898"
     rRNA            <1..>610
                     /locus_tag="LP345_002898"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          150 a          135 c          195 g          130 t
ORIGIN      
        1 gcagtttgac tggggcggtc gcctcctaaa aggtaacgga ggcgcccaaa ggttccctca
       61 gaatggttgg aaatcattcg aagagtgtaa aggcagaagg gagcttgact gcgagaccaa
      121 caagtcgagc agggacgaaa gtcgggctta gtgatccggt ggttccgcat ggaagggcca
      181 tcgctcaacg gataaaagct accctgggga taacaggctt atctccccca agagtccaca
      241 tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca tcctggggct gtagtcggtc
      301 ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag ctgggttcag aacgtcgtga
      361 gacagttcgg tccctatccg tcgcgggcgt tggaaatttg agaggagctg tccttagtac
      421 gagaggaccg ggatggactt accgctggtg taccagttgt tctgccaagg gcattgctgg
      481 gtagctatgt agggaaggga taaacgctga aagcatctaa gtgtgaagcc cacctcaaga
      541 tgagatttcc catttcttta agaaagtaag atccctgaga gatgatcagg tagataggtc
      601 aggagtggaa
//
LOCUS       DAFEIE010000192          587 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFEIE010000192
VERSION     DAFEIE010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.200"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            26..412
                     /locus_tag="LP345_002899"
     CDS             26..412
                     /locus_tag="LP345_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1761610.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT          221 a           93 c          118 g          155 t
ORIGIN      
        1 ataaaaataa aaaaggagat ctttcatgaa aaaaatttta gggttgatcg ttatcatatt
       61 gattgctttt ataggatgga aaggttggga ctactatcag tctacttatg taggtaaaga
      121 ttattatgcg gtagtcaaag ctccaatgcc tgcagaaact gatatcaaag cagataatgg
      181 ggaagtaatt ggaagaggtt ttaaatacaa cgtagatgct tatgctgaaa acggtgaaaa
      241 aagacagtta gatttcgatg tcattacttc tggtgactct gccaatggtt ctgcttaccc
      301 cgaaggaacg atcttgcagt tgaaagcaag cgaaaagcgg atcatagaga aaaaagtaat
      361 taccagcgat aaggtaccct catctgtaaa agaaaaatta ggcctatctt aagctaagaa
      421 tatatcgcaa aaaagcactc gaagtgagtg cttttttgct tactgattct agaaaacaaa
      481 aaaacagaat taaccttcga agtcagcctc actgttctta aagtcctaaa acaaactaaa
      541 gagcaaggca atcaatcgat ttctatacaa acaagggact gtgacaa
//
LOCUS       DAFEIE010000193          528 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFEIE010000193
VERSION     DAFEIE010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.denovo.202"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(5..90)
                     /locus_tag="LP345_002900"
     tRNA            complement(5..90)
                     /locus_tag="LP345_002900"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="LP345_002901"
     tRNA            complement(107..178)
                     /locus_tag="LP345_002901"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="LP345_002902"
     tRNA            complement(190..262)
                     /locus_tag="LP345_002902"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="LP345_002903"
     tRNA            complement(280..361)
                     /locus_tag="LP345_002903"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="LP345_002904"
     tRNA            complement(369..441)
                     /locus_tag="LP345_002904"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="LP345_002905"
     tRNA            complement(445..517)
                     /locus_tag="LP345_002905"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAFEIE010000194        27602 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.guided.032, whole genome shotgun sequence.
ACCESSION   DAFEIE010000194
VERSION     DAFEIE010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.guided.032"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            196..2385
                     /locus_tag="LP345_002906"
     CDS             196..2385
                     /locus_tag="LP345_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1761611.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            2382..4175
                     /locus_tag="LP345_002907"
     CDS             2382..4175
                     /locus_tag="LP345_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL1761612.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            4375..4689
                     /locus_tag="LP345_002908"
     CDS             4375..4689
                     /locus_tag="LP345_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1761613.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            4710..5087
                     /locus_tag="LP345_002909"
     CDS             4710..5087
                     /locus_tag="LP345_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1761614.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            5097..5870
                     /locus_tag="LP345_002910"
     CDS             5097..5870
                     /locus_tag="LP345_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761615.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            5892..7295
                     /locus_tag="LP345_002911"
     CDS             5892..7295
                     /locus_tag="LP345_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL1761616.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            7477..8661
                     /locus_tag="LP345_002912"
     CDS             7477..8661
                     /locus_tag="LP345_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1761617.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            8658..8948
                     /locus_tag="LP345_002913"
     CDS             8658..8948
                     /locus_tag="LP345_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761618.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            8945..9166
                     /locus_tag="LP345_002914"
     CDS             8945..9166
                     /locus_tag="LP345_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761619.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            9208..9987
                     /locus_tag="LP345_002915"
     CDS             9208..9987
                     /locus_tag="LP345_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBL1761620.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            10054..10548
                     /locus_tag="LP345_002916"
     CDS             10054..10548
                     /locus_tag="LP345_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1761621.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            10604..11242
                     /locus_tag="LP345_002917"
     CDS             10604..11242
                     /locus_tag="LP345_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761622.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            11314..11709
                     /locus_tag="LP345_002918"
     CDS             11314..11709
                     /locus_tag="LP345_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1761623.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            11693..14146
                     /locus_tag="LP345_002919"
     CDS             11693..14146
                     /locus_tag="LP345_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1761624.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            14143..16170
                     /locus_tag="LP345_002920"
     CDS             14143..16170
                     /locus_tag="LP345_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761625.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            16167..17096
                     /locus_tag="LP345_002921"
     CDS             16167..17096
                     /locus_tag="LP345_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBL1761626.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDPIGYGDLSSRYWQDHLIGARRVIHN"
     gene            17113..18042
                     /locus_tag="LP345_002922"
     CDS             17113..18042
                     /locus_tag="LP345_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1761627.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            18287..18403
                     /locus_tag="LP345_002923"
     CDS             18287..18403
                     /locus_tag="LP345_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBL1761628.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            18419..20338
                     /gene="tet(M)"
                     /locus_tag="LP345_002924"
     CDS             18419..20338
                     /gene="tet(M)"
                     /locus_tag="LP345_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBL1761629.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            20436..20624
                     /locus_tag="LP345_002925"
     CDS             20436..20624
                     /locus_tag="LP345_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL1761630.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(20682..21035)
                     /locus_tag="LP345_002926"
     CDS             complement(20682..21035)
                     /locus_tag="LP345_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1761631.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            21566..21988
                     /locus_tag="LP345_002927"
     CDS             21566..21988
                     /locus_tag="LP345_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1761632.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            21985..22215
                     /locus_tag="LP345_002928"
     CDS             21985..22215
                     /locus_tag="LP345_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1761633.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            22713..22913
                     /locus_tag="LP345_002929"
     CDS             22713..22913
                     /locus_tag="LP345_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBL1761634.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            22940..24133
                     /locus_tag="LP345_002930"
     CDS             22940..24133
                     /locus_tag="LP345_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1761635.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(24201..25766)
                     /gene="guaA"
                     /locus_tag="LP345_002931"
     CDS             complement(24201..25766)
                     /gene="guaA"
                     /locus_tag="LP345_002931"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBL1761636.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(25825..26748)
                     /locus_tag="LP345_002932"
     CDS             complement(25825..26748)
                     /locus_tag="LP345_002932"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBL1761637.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            26944..27549
                     /locus_tag="LP345_002933"
     CDS             26944..27549
                     /locus_tag="LP345_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1761638.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
BASE COUNT         9427 a         4590 c         5280 g         8305 t
ORIGIN      
        1 aaggtttcca acaggccgaa ggcgagctcg aacaaatgct aagccaactg attgagaatt
       61 agaaacaatc tgcagtaggg aagaatcatt tacacaaaat tattgacgct cccttataat
      121 gagaactttt actaacataa tttatgataa acttactata taatcatatt aattaaatag
      181 ttaggagatc tgcttatgtt tatatctact cttcaaattc gaaattttag aaattatgaa
      241 tccgaaatct ttcgattcga taatgagaca aatactatta taggtgagaa tgattcaggg
      301 aaaaccaatg ctcttactgc attgagaatc ttattagatg atagttatta ctatagtagt
      361 aaaacactaa aagaatcaga tttttttcat ggaattcaaa atgggtggca agggcattgg
      421 attattatct ctgcgacatt tgaaggaatc agcgaagaag aatttgacaa tgagatttgt
      481 gcttccattt ctttaaattc tgaaagtcaa acaatcttag aagaattgat ttcaaatgca
      541 gataaaggtg taggtagtat ttctctattt attagaccta acaaagctat tagaaagcaa
      601 ttatttgata tttccactga attagactct catcaattta acgaatttag aaattctatt
      661 cgtctatccg actatgaatt ttactacaca tctaaatcaa atctaaattt ctgtatcaat
      721 gaaaattatg ataaattggt aggaagactc aatgacaata tagctagtaa tcctgaagaa
      781 gacgatgaag ctctgttggg ctcaagaatt gacatgtcag atattttcaa gcatatttcg
      841 gttgtttatg ttgacgctct tcgagatgtt cttagagaaa tgaaaaacaa tcgaaaccca
      901 gtcaaaagaa tcatggaaac aattgaatca aaaatatcat cagataatgt tgagtcatta
      961 aaaacaatta tacagcaatt aaatgagact attaccagtg ttcctgaaat taggaaaatt
     1021 ggcgaaaata ttaatcggca actaaatagc ataattggtt cagtgtattc tcctaatctt
     1081 cttctttcct caactatgtc agatgatatg ggttctttag caaaatttct ttcaatgaag
     1141 ccagaacaaa atatcgactt agacttacta gggttaggac atctaaatat gatttattta
     1201 gctttgaaaa tagtcgaatt tgaagcgtgt cgttcaagag aactacttaa tattatgttg
     1261 attgaagaac cagaagctca tattcatcat catattcaaa aaactctgtt cgaaggatta
     1321 aatcttcaaa aaaactatac tcagattctc atgaccacac attctgtaca tttagctgaa
     1381 gtgtctgaaa tatctcggat gaatgtatta aaatcgttta atggcaaatc tatcgttatg
     1441 aatccagcaa ataatctgaa ctcatttgct aaagaaaagt taaaaaagaa caatctaaat
     1501 ctaataaacg cagtagagag atatttagat gttaaaagaa atggattgct tttttctaaa
     1561 ggtgttatct tagttgaagg agatgctgaa gaaatactta ttcctcaaat agtaaaaaaa
     1621 ttatttggta taaacttaga cgaacttgga ataggtttga ttaatgttgg tagtacttcg
     1681 tttgaatata tcgctagctt gtttgacgat gatagaatac agagaaagtg tgctattgta
     1741 actgatttag atgaacaggc aatcccatca gaacatcgat tgtataaaag cactgcacaa
     1801 gagaaaggtc aagcaagaaa agaaaaatta tcctcccttt ttaatgaaaa caattgggtt
     1861 aattgttttt atgctaatac aacatttgaa attgagtttt tagatgtgaa taaagaaaat
     1921 attctaactt atgtcagtcc aattatagat gacgcattca aagataaaaa aacaataact
     1981 gcttataaag aagaaataca aagtgaacaa tatttagaaa gaaatttagc gatgttaaaa
     2041 ctagccaatc atgttggtaa ggggtggttt gcaattgagt taggtgaaaa aattgacttt
     2101 ttaatcaaaa ttcctaagta tattcttaat gctattgctt ttgcatgtca ggaaatagta
     2161 gatctctcaa tttataaaaa aattctactc catacaatcg acttgtacga ggaaactaca
     2221 gaattgtcag ctttatcagc tagtttaaaa acaagtgata cagctgattt gaatatagca
     2281 ataatttctt tattagagta ctttggtaaa gatgaggatg ttgtgtatct aatcaatcag
     2341 atagaaaatt acacaaaaat actttatgct gaggtttcaa aatgacaaat atcttcgaaa
     2401 aaatcgtaaa tgatttaaat ttagaacaaa aagatgttgt ggaaagtgaa gataaccttt
     2461 atgtaaatgc atgtcctggg agtgggaaaa caagggtact tacaaggaaa attgcttacc
     2521 aagcaattaa acacgatgga tcactaaaaa gaataattgc tatcacatac actaatagag
     2581 ctgctgaaga aattaaggaa cgcctaagtt tacttagtat agatgatgat attaatattt
     2641 gggtggggac aatacatcag ttttgtcttg aatttattat ttatcctttt aaaatgaatc
     2701 tctcaagagt atcaaaagga tttacaatta ttgatgatta tactcaaaga gcttacgtca
     2761 gccaaattaa taatatgctg aatttaaatc tcaaaacgta tgaactgaac aaaattgatt
     2821 tgtcactttc tcatgatttt aaaattaatg aagttcagta tactcaagtt tctgaaatgt
     2881 atcacactat gttggaaaaa aataaagaaa ttgattttga tatgatttta ctagtagcgt
     2941 ataaaatttt aactgtaaac agtaacgttg cacgtaatat tgctagtaat ataagggcga
     3001 tttatgtgga tgaatttcaa gatactagag aattacaata caatgtaata gctaaattac
     3061 ttcaaaacaa ccctcaaatt cagtcaatgt ttgttggaga tattgaccaa gcaatttatg
     3121 gatcattaga tggtatagct aaatcagttg aagaactaga aatgctaact agtcacactt
     3181 ttcaatcaaa gacgctacat ggctgttaca ggtctaatca gagattagta gacttctact
     3241 ctaattttca gagttgtcct tacgagattg aaagcagagg gaataataaa aacgaccgtg
     3301 gttttataag ttatgattgc aaagttacta aggaggattt acccaacata ataaaaaata
     3361 taataaagga aaagattgaa agcggcattc atgaaaaaga tatttgtgta cttgctcctc
     3421 aacactatcc tctgttttca ctgggtgagt atttaaagaa agaattaccg tattgcaatt
     3481 ttgatgctat aaatatatca ccaattaagg taaataatca tagtttattt ttcaagttag
     3541 caattttgta ctttactgaa tcaggtgaaa aggttcgaag aagaaagcta attgcaaacg
     3601 atattttaat tatattaaaa aatgaatttg gaatagaagt taaagattat tttattgact
     3661 tagatttatt acagctaata aacagtgtga aaagaatgta tagtggagac gacaacggtg
     3721 ttgatttata caaatttgtt accaaacata tatttgttaa tcttaatatt gacgagaaaa
     3781 attacccgtc tatttttaag cactatctat tttttattaa cgaagtagaa gatcggataa
     3841 aaaataattc attatctagt agtgtatcta gttttaagaa gatgtttaaa tctcgagatg
     3901 gtatcacact tactacagca cataaagtta aaggaaatga gtatgatact gttatcgcta
     3961 ttaatcttct aaacgggaaa attcctcatt ggaatgaaat ttttaatgtt tctgataaag
     4021 gaattagttc agcgagaaaa ctactatacg taatttgttc aagagcaaaa aataatttat
     4081 ttcttttctc agaggtgggt tattttacga gtaaaggaga cttgctttat cccactcaat
     4141 tattagataa aatagaattt gattataata tttaaaatac ctaggtagtc gttgttttaa
     4201 atatagtagg aatcggacgc tcagtacgga gcgtctattt ttttacccaa ttttgaaagg
     4261 aagtgaactt atgaaaataa aaaatcaaga atcaaaaggt cgctctcccc cctttaaaac
     4321 catcacacaa ataagattca ttcaaacata aaaacagaaa ggataggtaa aaatatggaa
     4381 cttaaatatg tcattcccaa tatggaaaaa acatttggac aattagaata tgctggtgaa
     4441 gggaacattg aacaacgtcg aataaatggc agaccaacca ttctctctcg tagttacaat
     4501 ttatactcaa cgattcaacg agcagatgat attgttgtca ttcttccctc cgaagctggc
     4561 gagaaacatt ttgaatccga cgaaaaagtc aaactcatca acccacatat taccgcagaa
     4621 ggttataaaa ttggcaatcg aggatttacc aattacatta tgcacgcaga cgatatggtg
     4681 aaagcataag aaaggaaagg tgaaaaaata tgagattagc agaaggtatt gtgattgaaa
     4741 aagaccagac atttggcaca ttgaaatttt ccgccttgcg tcgtgaggtt cgtatccaga
     4801 atgaagatgg tacggtttcc gaagaaatta aagaacgtac ctatgactta aaatcaaaag
     4861 gacaaggacg catgatacaa gtcagtatcc ccgcttctgt tcctttgaaa gaatttgact
     4921 acaacgcaga agtggaatta atcaatcctg tggcagatac cgtagcgacg gctacttttc
     4981 gaggggcaga cgttgattgg tacgtgaaag cagacgatct tgtattaaaa ggacagacaa
     5041 aacctcatca gaaatataaa aaagaagcgt ccgaaagtga aaaataggtg ttgcttatga
     5101 caaacacacc attgattttg aaagaaattc cgaaggatga agccatttct tttattcggc
     5161 aataccatta ttcaaagata ctccctagat tgtgtaaata ctttctaggg attttttcag
     5221 aagaaaaatt attaggcgtt gtggaattag gctggggtac gcaaccccta caaaccatac
     5281 gcaaactctt tcccgacagt tcccttcaaa ccacagatta tttagaaatt ggaaagatgt
     5341 gttttcttcc agaaatgaat caaaccaatt attttggcag tcaagctctt tcagctctaa
     5401 ttaagtggtt gaaagaacat acggactgtc attttttata tacactggca gatggaattg
     5461 agggaaaatg tggctatgtc tatcaagcgt ccaacttctt ttactgcggg tatttcaaga
     5521 caagtgtcta tcgtgataag cagtcatggg aaaagataca ccctcgaagt gctcgccttt
     5581 tattagagga aaatgctcgc tttgaacagg tagagaaaaa gcattggctt tcccaggcat
     5641 tttgcgaata caaagggatt gagaaaatca atggacgcat gtttcgctat ctctatccgt
     5701 tgacaaaaga agcgaaaaaa ctgttaggac acactctcta tcgacgtcat tattatccga
     5761 aagaaaaaaa tttacgcttt gaaaagcgaa tcgcttatca gaaatatgaa gccatttctc
     5821 aaccaacttt tgataaacag gctcgtatct acaatacaca attattttga taggtggaaa
     5881 ggaggatttt tatgccattg cttcatgaca gaggagagcg aatcaaagcc aacgataagc
     5941 acttggtcta tcattttgta ctaatttcat tgctggtagt ttttctagtc gtcctactcc
     6001 cttttcattg gagagcgtta caatcggtga actggcaagc agttcagtta gatacatttt
     6061 tctatcaact tcatacgcca tacttttgga gcagtattct cactgctctt tttgtatgcg
     6121 gacttatcag ctggctttat tatcactatc gtatagattc tataaaacag ttagagcacc
     6181 gtcaaaagtt agctcgtatg attttagaaa atcattggta tgaagccgaa gaaactcaat
     6241 cagagggatt ctttaaagat ttacccagca agaaaaccaa acaacgaatc cgccattttc
     6301 ctaaaatata ttatcgaatg aaagatggac taatccatat tcatgtagaa atcaccttag
     6361 ggaaatatca agatcagctt ttgcacctag aaaacaaact agaaacagga ttgtattgtg
     6421 aattagtgga aaaaacgttg aaagattctt atgtagagta tgtcctactt tatgatacta
     6481 ttggcaatcg aattggcatt gaagacgtgg tagctcaaga tggacgtgtc aaattgatgg
     6541 aatcggtcta ttgggagttc gattctctcc ctcacatgtt aattgctggg ggcactggta
     6601 gtggaaaatc ctattttatt ctcacattga ttgaatctct cctgcataca aatgcaaagc
     6661 tttatattct tgaccctaaa aatgctgatt tggcagactt aggggcggtc atgaataatg
     6721 tctattaccg taaagaagat atgttggcat gtatcaatca attttacgaa gatatgattg
     6781 atcgcagtga aaccatgaaa caacacccta actataaaac aggagaaaat tatgcttatc
     6841 ttggtttgtc tgccaatttt cttatttttg atgaatatgt ggcaatgatg gatatgctag
     6901 gtcgtgaaag taccaccgtt attcataaac tcaaacaaat tgtaatgtta ggacgacaag
     6961 caggcttctt tttaattctt gcctgtcaac gtccagacgc aaaatatttt agtgatggga
     7021 ttcgggacaa ctttaacttc cgtgtggctt tgggtcgtat gtctgaaatg ggctttggta
     7081 tgatgttcgg aagcgataca caaaaacaat ttttcttaaa acccatcaag ggaagaggtt
     7141 acgtggatac aggaaaaagt gtgattagtg agttttatac accccttgta ccaaaaaggt
     7201 acgatttctt aggagaaata ggaaaagtca ttcaaaaaaa gcaatctgag cctgtaccgc
     7261 acgaagtgaa aggtacaggt tcagacttgc tttgattggt gtggcgttag ccacgccaat
     7321 cctttagccc cctctatcta acaggggggc acaaatacaa ctgaaaacag gcaattctca
     7381 tcaaccaatg ttgatggtac aaaggattgc ggaaaatatg aaaggtgtaa actcaagggt
     7441 catagtttac atctttttta gattggaggt ttgcgaatgg aaaacgaaaa aatttggatt
     7501 aaggaattga aagaaaagcg actggcttat ggcgtttctc aaaataaact ggcggttgct
     7561 tctcatatta ccagacctta cctatcggat attgaaacag gcaaggcagt ccctactcaa
     7621 caggtgaaag aagatttact gaacgctttg gaacgcttca atcccgataa cccattggag
     7681 atgttattcg actatgtacg gattcgattc cctaccaatg atgtggctca aattatcggt
     7741 gaggttttac gtttgaatat ggattatatg ctacacgaag actttggcta ttattcttat
     7801 cccgaacact atcgtttcgg tgatattgtt gtcctagtct ctcatgatgt aagtaaaggt
     7861 gttttattag aactgaaagg aaaaggctgt cggcaatttg aaaactttct attggctcaa
     7921 catcggagct ggtatgattt ctttcaagat tgcatggaac ataaaggtat tttcaaacgc
     7981 ttggatttag ctatcaacga taaaacaggg attttgaata ttccagattt ggcaaagaaa
     8041 tgtaaacagg aagaatgcat ttccgtcttt cgaagcttta aaaattatcg cagtggtgaa
     8101 ttggttcacc gtgatgaaaa accatacatg ggaaacacac tttatattgg ctcattaaaa
     8161 agtgaagtct atttctgtat atatgagaaa gattatgagc aatacgtgaa aaatgatgtt
     8221 cccttagaag acgcagaagt aaagaatcgg tttgaaattc ggttaaaaaa tgaccgagcc
     8281 acccaagcca tgaaagattt attggcacat caacaggcgg aaaaaacagc ctttgaaatt
     8341 atcaatcgct atatccgctt tgcagataaa gacgacacta aacgtcggag tgattggaaa
     8401 actaatgaac gttgggaatg gtttatcggt aaaaatcgtg gagcattacg cctaaccaca
     8461 cagccagagc cttattcttt tgaacgaaca ttgaactggt tacatcatca agtcgcccct
     8521 acattaaaaa tcgcaagcat tttagatgtt ctcaacggta caaccattat ctccaccatg
     8581 attcaggaag ccaaactgac agaaaaacat gagaaattaa ttgaacaaca acatctagcc
     8641 atggaggatt tgattacatg agccttttaa caaaagaatt aaagaagtta gggtttcagt
     8701 gtggcattga gtttcaagcg tatatacaaa atacagggaa atatacgtct ctcattattg
     8761 agggaaaacg gcaagctggt gataccatct atacctatga tttttacaag gtgagatttt
     8821 ataataatta taccaatcga gtaaccgtct atggagagca tttaacccct tttcaattat
     8881 taaggcgtgt aaaaagctat atctattatc gagaaaaata tcttaaggaa aggaggacaa
     8941 tcacatgaat tttgggcaga atttgtacaa ctggttcttg gataatgcac agtcattggt
     9001 attgttagcg attgttgtca ttggactgtt tttaggtttt aaacgagaat tttcaaaact
     9061 cattggcttc ttgattattg ctctaatcgc cgtcggactt gtgttcaatg cagctggcgt
     9121 gaaagatgtg ttattaaact tatttaaccg aatcattggt gcttaacaga tatttttcat
     9181 gataaaatag gaagtatata ttttgttatg aaaggattta tgaatatgtt tacaaatgat
     9241 caatttaaat ctcttttaat taaaacatta gaaagaaaga gctcttcaaa ttattatgaa
     9301 ggaggtaacg agattgtttc taaaatgaaa atatcagagg taactttaga tgagactgac
     9361 gattttactt attataaagg atataaaaag ggctggaata cgctttgcac atatcttaaa
     9421 ataagagttc cttttgatga tttagacttt tttgaaagtc ataaagattt gattacccag
     9481 acagcaagct ccatatatga taaacaaggt gataatgtat tagtggatac tattttagta
     9541 ccacttccag agaattacga agtaattaac tttagtcagt tgaaaattag tgatgtggtt
     9601 tcacaagcta ttgaagacgc tgagtctttt atgagtaatg gtgaatatca acgtgccttt
     9661 gacagagttc acactgcttt tcatggatat ttaattgaaa tactaaaaaa atatgaaatt
     9721 acagttccta gagacgaaaa tctatctaaa ttatatagta ggatacaaca attaattgaa
     9781 aaagaaattc aacctactga acttgctgat atagtgaaga caacgataag gtcatcaaat
     9841 ggaatgatta gctctcttaa tgaagcaaga aataggcatt cacttgcaca ccctaataca
     9901 aatattattg gaaagagaga agcaaaacta ataataggta tttcaagtac agttacagat
     9961 tatattagcg gataccttga taagtagcgt cattaactga ttgctacttt ttttatgact
    10021 atttttataa aaaggatgtg ataagaattg gaaatgaaag tctatgtggc aaatttagga
    10081 cggtataatg aaggtgaatt agtcggagca tggtttactc caccaattga tgaggaagaa
    10141 atggcagaaa gaatcggttt aaatgaggac tacgaagaat atgcaataca tgattttgag
    10201 cttccttttg atgtggacga atacacgccg attagtgaaa tcaaccgtct atgtgaagcc
    10261 attcaagaaa tcgaaggtac acctatttat aatgaactca aagaaattca aggcatgtgg
    10321 tttagtagct tggaagaatt actggaaaac aaagaggata ttcattgtta tagtgattgt
    10381 gattcgatgg aagatgtcgc ccgttattac gtggaagaaa caggacagct tggtgaagtc
    10441 ccttccaatt tacaaaatta tattgactac caatctttgg gacgtgatat ggaaatagag
    10501 ggtaattacc tagttacctc tcatggggta tttgaatatt gtcagtaagt ttaacaatcc
    10561 gtgttataat taaattaata aatagcacgg agaggtataa attatggtaa atgtatttga
    10621 aaatcttaaa ctattaaaac tagacatgaa agataaaggc tgggtgatag attcctttta
    10681 ctttcgttac aaacagcaaa attatattgt acttgttaag ctatttgaaa aagaggaaaa
    10741 agttccagaa tatgctctgt taaaactaga atttttaaag gaaaacgatt tttcagatat
    10801 gctagctgtc tatgctaatt cggtaaaatt atatacagac acgaaaacaa taagagaata
    10861 ttttggtatc gaatacagta gtaacttggg agatgtttta tttcaattta gccaaactct
    10921 tgctcgattt attccgacag aagttagtga gaagaaaaat gaagaccaaa aagaagccat
    10981 gtgtttctca ttaagtcaaa gtgattcaga agatcccaga aaaaaatatt gtttttcagt
    11041 tagaagaaat cctttaaagg gaaatggtga gctgggaaaa cgaagtcctt ttaatgacaa
    11101 taaaacgaga ttgtatagac ccagcttata tgaacgatta gggtcagata ccaatttaag
    11161 tttcagatat tcaatgaatc cagatgatga agaaactgat gaaggtatta ttgcaaaatg
    11221 gacaaaaaat aaaattgaat agttaaagca ttgaaagagc aatcacctat tttgattgtt
    11281 ctttttctat ttttacggaa aggacgtgaa gacatgaaaa aaataagaag ttacaccagt
    11341 atttggtcag tagaaaaagt gatttatgcg attaatgatt tacaactccc tttcccaatt
    11401 acctttacgc aaatgacatg gtttatcgtt tctttgtttg tcgtcatact ctttggcagt
    11461 ttaccaccac tttctctgat tgacggagca ctactcaaat acttagggat tcccattgtt
    11521 ctcactgggt tcatgtgcca aaagaccttt gacggaaaga aaccctatgg atttctaaag
    11581 tctatcatta cctatgctct acgccctaaa gtaacctacg ctggcaaaca aatacgatta
    11641 aaaaaagaaa caatgaatga atcgattacg attgtaagga gtgaacaact agatggcata
    11701 tccgattaaa tatatggaag ataatctcgt atttaatcat gatggcgaag tattcgctta
    11761 ttatgaatta attccctata attacagttt tttaagttcc gatgaaaaaa ttcaagttca
    11821 tgataatttc tgtcaattga ttgcccaaaa tcgtgatggc aagattcatg ctctgcaact
    11881 agcaaccgaa tcaagtattc gagccacaca ggaacaatcg aaaaaagaaa tcactggacg
    11941 attaaaagag atagcttacg aaaaaataga tgaacagacc gaagcgttaa tttctatgat
    12001 tggtgacaat caagtagact atcgcttttt tattggtttt aaactctacc tcaatgaaca
    12061 ggaagtatcc gtaaaaaatg ttgggaaaga aattcaaaaa gcatttgcgg aattctttca
    12121 tggtgtgaat cacaaattaa tgggcgattt tgtttctatg cctatggcgg aaatcgaacg
    12181 cttttctaag atggaacagt tgttagaaag taaattatcc agacgctttc agattcgtaa
    12241 attggagaaa gatgattttg gttatattat tgaacatctt tacgggcaaa caggtgtccc
    12301 ttttgatgac tacgactacc atttaccgaa acgatacgaa gataaaaaag tgttggtaaa
    12361 gaaatacgat attctcaaac ccactcgctg tttaatcgaa gaaaatcaac gctatttacg
    12421 gattgaacag gaagatacca ctacttatgt ggcgtatttt acaattaata gtattgttgg
    12481 tgaattggat ttccctaata gtgaaatttt ttattaccag caacagcagt ttactttccc
    12541 cgttgatacc agtatgaatg ttgaaattgt cgccaataaa aaagccttat ctaccgttcg
    12601 caataaaaag aaagaactga aagatttaga tagccacgca tgggaaagcg acaacgaaac
    12661 cagtactaat gtggtggacg ctttagaatc tgtcgatgaa ttagaaagta atttagacca
    12721 aaccaaagaa tctatgtaca aactaagcta tgtggtacgg gtatcagcaa agaatttgga
    12781 cgagctgaaa caacgttgtg atgaagtaaa agatttttat gatgatctgt ctatcaaatt
    12841 agtacgacct tttggcgata tgctaggctt gcataatgaa tttattccct caagcaagcg
    12901 atatatcaat gactatattc aatatgtcac gtcggatttt ttggctggtc ttggtttcgg
    12961 tgctacacaa atgattggtg aaaattctgg tatttacgtc ggttacaatc tcgatacagg
    13021 cagaaatatt tatctccaac ctagccttgc aagtcaagga attaaaggct ctgtaacaaa
    13081 tgcattagcg tccgctttta ttggttcatt aggtggcgga aaatcattct ctaacaatat
    13141 gctggtctat tattcagtac tctttggcgg acaggcaacc attgttgacc caaaagctga
    13201 acgtggtgaa tggaaagaaa ccttacctga tattgcccat gaaatcaata ttgttaatct
    13261 cacgagtgag aacgacaata aagggttact tgacccttat gtgattttaa aactcccgaa
    13321 agattcagaa agccttgcca ttgatattct cacgttctta acaggtattt ccagccgaga
    13381 tagcgagaag tttcctgtcc tgcgtaaagc tattcggagt gtaactcaaa gcaaacaacg
    13441 agggttgtta ttggtgattg atgaattgcg aaaagaagat acgcccatca gcaatagtat
    13501 tgctgaccat atcgaaagct ttgtcgatta tgattttgcc catctgttat tcagtgatgg
    13561 cagtgtcacc caatccatta gcttggaaaa acaactcaat attattcaag tggcagattt
    13621 ggtcttaccc gattccaata gctcttttga agaatacact accatggaat tattaagtgt
    13681 ggcaatgctg attgtcatta gtacctttgc tttagacttt atccactctg accgttccat
    13741 ttttaaaatt gttgaccttg atgaggcttg gagtttttta caagtggcac aaggaaaagc
    13801 tctatctatg cgattggttc gagcaggacg tgccatgaat gcaggggtct atttcgttac
    13861 tcaaaacgcg gacgatttac tagatgaaaa gatgaagaat aatattggct tgaaatttgc
    13921 ctttcgttcc actgacctag tggaaatcaa aaagacctta gaattttttg gtgtggacaa
    13981 ggaagatgaa aacaatcaga aacgcttacg tgaattagaa aatggacaat gtttagtttc
    14041 agacatctat ggtcgtgtag gggttatgca gtttcacccg atttttgaag agttgcttca
    14101 tgcctttgat accagaccgc ctgtgcgaaa tgaggtggaa gaatgacaca aaaacaaaag
    14161 aaatttcttc actatagttg gataacgctc ctttgtgtgg gcgttatttt acttttatta
    14221 ggcacgctgg gcaatgcagt acaagcgaca ggcttagttg atgaaaccat tgatacaagc
    14281 aatgaatact ccaagtatgg tttgaatcaa tatcagcttg attattatgt ggacaatagc
    14341 tggggctggc ttccatggaa ttggagtgat ggcataggac aatcggtgat gtatggattg
    14401 tatgccatta ctaattttat ttggacaatt tctctttatc tatcgaacgc cacaggttat
    14461 ttggtgaaag aagcctatgc cttagatttc attagtcaaa catcccaagc aattggcgaa
    14521 aacatgcaga cgattgcagg cattacaccg aatggctttt ccagttcagg gttttatgtc
    14581 ggtttcctcc ttctttttat tctcattgtt ggaatctatg ttgcctatac aggattggtt
    14641 aagcgagaaa cgacgaaagt gatacgagct gttttaaact ttgtcgtggt gtttattcta
    14701 tcggcttcct ttattgcgta tgcacccgat tatattgcga aaatcaatga tttttccaaa
    14761 gatgtcagta ccgccagtct gaatattggg acaaaaattg ttcttcctaa cacggatagt
    14821 caagggaaag acagtgtgga catgatacgt gacagcttat tctctgttca agtaaagcaa
    14881 ccatggctat tgcttcaata tggctccact gatgtagaag cgttagggga agaacgtgtg
    14941 gaaagtttat tgtctaccag tccagataca aacaatggtg aagatagaga aaatgtagtg
    15001 attgaagaaa ttgaagatca tgacaatacc tatttaaccc taccgaagac gatttccaga
    15061 ttaggaacag tcttcttttt gtttgtattc aatattggta tctcgatttt tgttttcctt
    15121 ctaacaggaa tcatgatttt ttcgcaagtg ctatttatta ttttcgctat gtttttgcca
    15181 atcagtttcc tattaagtat gttgccgagt tttgatggca tgggcaggca tgccattacc
    15241 aagttattta atgtgattat gacaagggct ggtattacct tgattattac cgttgccttt
    15301 agtatttcca ctatgcttta ttcgctgtca gcaagttctc cctttttcat gattatgttt
    15361 ttacaaattg tgacctttgc agggatttat tttaaactgg gcgatttaat gagcctattc
    15421 actttacaaa gcaacgactc tcaaaacatg ggcagacaag tgtttcgcag acctcgtcaa
    15481 atgatgaatc gacaaaccag aagatttcaa cgcagtatga gtaagatttt tcgtggaaaa
    15541 gcagggtcaa cgaagcaaaa gacaatgaca acaaagcaga atcaaaccaa taaagctaac
    15601 catactcgtc aaaatgaacg gactacacca aagaaagaaa cagcactttc caatgtgaaa
    15661 aagcaacaag gcggtatcgg gcaacgatta ggtgaaaaga cagcccatgt attggacacg
    15721 aaaaatcgtc tagtcaataa aagaaagcag gcaaaacaac agatacaggc gacaccaacc
    15781 catgtcaaat atgcccttca tcaaggaaaa gagaatgtca ctcataatgt aacagacttt
    15841 aaacaatcta tggcagatac caaagctcaa cgcaaacaac agcgtatgaa ccagcaggag
    15901 caaaaacgaa agaacattgc tcaaaagcgt ttggagctgg ataaagcaaa agaaaaaaga
    15961 cgaaaagaaa acccatcatc tcctgttcag aataaccagc agcatgttcg caagcgtcag
    16021 caaaccgtca cgcctgtttt gtcacaaaac actaaacgtg aaaatcatca gcgaccattg
    16081 aaaaaagagc aaaaacaaaa gacaccaccg aagcaattca atcagaggaa gctaaataaa
    16141 agaacggata agcgaggaca acaaacatga agctaaaaat aacagtgatt tgtagtgtgg
    16201 tcttctctct cttctttttt ctcttattat tcctagtcat tttctttgca gatgatacgg
    16261 acagtggcga aaacaacaag gattcttcta ttccacaagg cggtgtgacc gtttcaccag
    16321 aagtgttggc acaccgtccg ttgattgaaa aatatggtaa ggaatatggg attgaagact
    16381 atgtttctta tatcttagcc attatgcaag tggaatcggg cggtacagca gaagatgtta
    16441 tgcaaagttc cgaatctttg ggtttaccgc ccaacagttt gagtaccgaa gagtccatca
    16501 aacaaggggt taaatatttc agtgaattat taaccagtgc agaacaacaa ggagtggata
    16561 tagattctgt tatccaatct tataattatg gcggtggctt tttaaattat gtgaggagtc
    16621 atgggaaaaa atatacctat gaattagccg aacagttttc taaagagaag tcgggtggtc
    16681 aaaaagcaga ctatcccaat cctatagcca tacctgtgaa tggtggttgg cgatataact
    16741 atggaaatca gttttatgtt cagttggttt cacaatacct aaccgacact tccccaacag
    16801 aatttgatgg tgaaaccgtg caagtcatta tggacgaagc cttgaaatac gaagggtttc
    16861 cctatgtctt tggaggggcg tcgcctacca cctcttttga ttgtagtggc ttaatacaat
    16921 gggtgtatga caaagctggc atttctctcc ctcgtgtcgc ccaagatcag tatgacgcta
    16981 cgcaagaaat ctctatggaa gaagcccaag caggcgaccc aatcggttat ggcgacttaa
    17041 gcagtcgtta ttggcaagac catctgattg gggctagacg tgttattcat aactaagaaa
    17101 ggaatgaatc aaatgattat aaaaatcgag cgaaaagaaa agaaggagaa accaaagaaa
    17161 tctaaaaaac cgagcaagca aagaaaagtt ccgatgatta aagttggcac gcataagaaa
    17221 ttaacctttg ttttatgggt tttattgatt ggtagtgtcg gatttggaat ctataaaaat
    17281 tttactgcca ttgacactca tactgtccgt gaaacagaaa tcattaaaca gcagattgtc
    17341 gataccaacc aagtagaaag ttttgtgaaa tcctttgcga aagactactt ttcgtggcaa
    17401 caatcccaag aagccattga taaacgaaat gaaaaattga cccattattt gacggaagaa
    17461 ttgcaggtat taaatgaaga aatgattcgt aaggatattc ctactagttc tagtgtgaac
    17521 gatatacagg tgtggcaggt ttctcaagtg aatgagaaca cctttgaggt actgttttct
    17581 gttgaacaag ttattaccga agacaaagac aaggaaacta tatcgtctag ctttcatgtg
    17641 gttgtccata tagatgaatc agataatatg gttattatca aaaatccgac aatgagtaag
    17701 aaacctcaaa aatcggacta ccaacccaaa cagctagaaa gtgaccatac agtagataca
    17761 gaaacgatgg acgaaatcac tagcttttta gaaacgttct tccagctcta tcctaccgcc
    17821 acagaaaaag aattgactta ctatgtaagt aatcatgtgt tacctatgat taacaaggaa
    17881 tatgttttcg aggaattggt gaatcctatc tttaccagaa aagataacca agtaatcgtg
    17941 aatgtcgctg tgaaatattt agatcaagaa acaaaggcaa cccaaatctc gcaatttgag
    18001 ttgatattag aaaaacaaga taattggaag attgtaaaat aacaaatatt ggtacatgat
    18061 tacagatact ttgtaatcat gtactctttt tgataaaaaa ttggagattc ctttacaaat
    18121 atgctcttac gtgctattat ttaagtgact atttaaaagg agttaataaa tatgcggcaa
    18181 ggtattctta aataaactgt caatttgata gcgggaacaa ataattagat gtcctttttt
    18241 aggagggctt agttttttgt acccagttta agaatacctt tatcatgtga ttctaaagta
    18301 tccagagaat atctgtatgc tttgtatacc tatggttatg cataaaaatc ccagtgataa
    18361 aagtatttat cactgggatt tttatgccct tttgggtttt tgaatggagg aaaatcacat
    18421 gaaaattatt aatattggag ttttagctca tgttgatgca ggaaaaacta ccttaacaga
    18481 aagcttatta tataacagtg gagcgattac agaattagga agcgtggaca aaggtacaac
    18541 gaggacggat aatacgcttt tagaacgtca gagaggaatt acaattcaga caggaataac
    18601 ctcttttcag tgggaaaata cgaaggtgaa catcatagac acgccaggac atatggattt
    18661 cttagcagaa gtatatcgtt cattatcagt tttagatggg gcaattctac tgatttctgc
    18721 aaaagatggc gtacaagcac aaactcgtat attatttcat gcacttagga aaatggggat
    18781 tcccacaatc ttttttatca ataagattga ccaaaatgga attgatttat caacggttta
    18841 tcaggatatt aaagagaaac tttctgccga aattgtaatc aaacagaagg tagaactgta
    18901 tcctaatatg tgtgtgacga actttaccga atctgaacaa tgggatacgg taatagaggg
    18961 aaacgatgac cttttagaga aatatatgtc cggtaaatca ttagaagcat tggaactcga
    19021 acaagaggaa agcataagat ttcagaattg ttctctgttc cctctttatc atggaagtgc
    19081 aaaaagtaat atagggattg ataaccttat agaagttatt actaataaat tttattcatc
    19141 aacacatcga ggtccgtctg aactttgcgg aaatgttttc aaaattgaat atacaaaaaa
    19201 aagacaacgt cttgcatata tacgccttta tagtggagta ctacatttac gagattcggt
    19261 tagagtatca gaaaaagaaa aaataaaagt tacagaaatg tatacttcaa taaatggtga
    19321 attatgtaag attgatagag cttattctgg agaaattgtt attttgcaaa atgagttttt
    19381 gaagttaaat agtgttcttg gagatacaaa actattgcca cagagaaaaa agattgaaaa
    19441 tccgcaccct ctactacaaa caactgttga accgagtaaa cctgaacaga gagaaatgtt
    19501 gcttgatgcc cttttggaaa tctcagatag tgatccgctt ctacgatatt acgtggattc
    19561 tacgacacat gaaattatac tttctttctt agggaaagta caaatggaag tgattagtgc
    19621 actgttgcaa gaaaagtatc atgtggagat agaactaaaa gagcctacag tcatttatat
    19681 ggagagaccg ttaaaaaatg cagaatatac cattcacatc gaagtgccgc caaatccttt
    19741 ctgggcttcc attggtttat ctgtatcacc gcttccgttg ggaagtggaa tgcagtatga
    19801 gagctcggtt tctcttggat acttaaatca atcatttcaa aatgcagtta tggaagggat
    19861 acgctatggt tgcgaacaag gattatatgg ttggaatgtg acggattgta aaatctgttt
    19921 taagtacggt ttatactata gccctgttag tactccagca gattttcgga tgcttactcc
    19981 tattgtactg gagcaagcct ttagaaaagc tggaacagaa ttgttagagc catatcttag
    20041 ttttaaagtt tatgcaccac aggaatatct ttcacgggca tataacgatg ctcccaaata
    20101 ttgtgcaaat atcgtaaata ctcaactgaa aaataatgag gtcattatta ttggagaaat
    20161 tcctgctcga tgtattcaag attatcgcaa tgatttaact ttttttacaa atgggcttag
    20221 tgtttgttta gcagagctaa aaggatatca ggttaccact ggcgaacctg tttgccagac
    20281 ccgtcgtcta aatagtcgga tagataaagt aagatatatg ttcaataaaa taacttagtg
    20341 cgttttatgt tgttatataa atatggtttc ttattaaata agatgaaata ttctttaata
    20401 tagatttgaa ttaaagtgga aaggaggaga ttgttattat aaactacaag tggatattgt
    20461 gtcctatttg tggaaataaa acaagactac gaatacgagt ggatactata cttaaaaatt
    20521 tccctttata ctgccccaaa tgtaagaacg aaactttaat taatgttcaa aaaatgaata
    20581 taataacaat caaagagcca gacgccaaga cgcagagccg ataatttgag aaatgaaact
    20641 ctcatcttat cggctctttt tgtttatctg aattttactg actagccttc aatatttctt
    20701 gcttcattga taccttttgc tagtgcttcc attaaggata gttctttgtc tgtaaagcta
    20761 tccatgtatt tttctacctg taaccttcga gtgcttttaa tcaaattatc tgtaggtaag
    20821 aaaaattcat caatagatac atggagtaat gatacaagat catacagcac ttgtgtactt
    20881 gggtgttgtc ctttgttttc tatatttgtt aaataacgtg ggtcaatttc aatcattgtt
    20941 cccacttgtt cacgagtgag accccgtttc attcgagcct ctttaatcgc taaaccaacg
    21001 gctctaaaat cgtatttatc ttctttttta cgcatactaa atcacctcta tacattttac
    21061 tgttcctata taaccataaa caggtataga aaaacatgtt atatagttta tgagttccta
    21121 tagaacactg tggaatttat taatgcgatg aatccaattt caaatagaaa ggtcgctgat
    21181 tttatttacc tatacaactt tataaaattt agtcatactc ctagaaagta gataaaattg
    21241 gcgacttaat ggagggaaaa gtcgccatga gaaagataat ctgtcatcta gttctcttaa
    21301 ttaagttctt atcaaaaaaa cttatccacc tgtactggat agatatgacc atcaatgtgg
    21361 ttttgcagat tacatagata gaaaaatcaa agcatatgaa cagagaaaac aatctgttta
    21421 tgtgcttttt tggtcactta ataaatatct tttaggattt ctcttcattt atgcaacaaa
    21481 tccccctttc gtgtcggggt ttagtatgaa gggagataaa gaagcacatg ccactccctt
    21541 tcacgacaga aagggggtga aaagcatgaa accatcttct tttcaagaaa ccatagaaaa
    21601 tcagtttgac tatatctgca aacaagttat tgaagatgaa cgaaaagatt acttcaaaca
    21661 tctagacaga ctatcagcaa aagaagtctc gttttctgat atagataact accttgtcaa
    21721 ctctttttct actgttgata cgtacgtcac tgatttccaa ctatttaaat tatttggatt
    21781 aagaatcaat gttgaaagtg atttattaag tgaagccctg cgtcatcttt cagagaaaaa
    21841 acggaacatt attttacttc attactttat ggatatgagt gatgtggaga ttgcggagtt
    21901 actaaatttg aatcgttcga ctgtttatcg tcatcgaata agtggactag ccatgattaa
    21961 agaattcatg aaggagtgta aagaatgaaa acagcttatc caagggttcc cttccccctc
    22021 attgtaaagg cgacagatgg cgacgtggaa gcaattaatc agattgttaa acattatcga
    22081 gggtatacct caaaacgttc attacgtcgc atgacagacg aatatggaaa ttctcatatg
    22141 gttattgatg aaaccctacg tggcagaatg gaaacgaaac tcatctctaa gattttatcg
    22201 ttcgaaatta aatagtccca ttttttcgtg gaagcgtgtc gaatcgtatc cacgcttccc
    22261 gatttgggag gtttgttatt ccatcaaagc atattgtgtg ttcagtaggt tttgataggc
    22321 taacaagcca aacgttcttt gacaaccaaa taaaggcaat cgaatacgtt tcggtaagaa
    22381 aagagctgat gaactaacac gccatgacct acaaaattag tgagcgattc atgttagtaa
    22441 ttcgaaagta atctttagca ggattgctgc catgactttc ttatcgtgat aatgatactc
    22501 ccgtatagcc atagtccgag cgttagaagc gtcacaggca atgggtacgg ctacatgaga
    22561 accatgcaga agtgaaattc ctgtgagctt tgctagagct gttcgattgc taagatattc
    22621 ttctcttgtc agtgtattat tataaaacta tttgatataa ttataggtga atattggagt
    22681 tttcctagcc tataattggg aaaggagtaa taatgataac ggtcacaaaa aaggatttag
    22741 ttgagctagg atatggaact tctttttcag cagacatcat aaaaaaagca aaagaattga
    22801 tgattacaaa agggcatatc tactatcaat ctcgaaagct agatagagtc cctcgtgaag
    22861 ctgttgaaga aattctagga attcggtttt caaatgaaaa caggtctgag tagtttttgc
    22921 acagtaagga gtaaaaacta tggttaaaga cccaataaaa aaagcaaaga atggaaccta
    22981 ttattttcgt gcaaatctag gttatgattc taaagggaaa aaaattcaaa aatatcgtag
    23041 tggattcact actaaaaaag aagcaagaga agaatattcg aaactgctat tgatgaaacc
    23101 agaagaatta agtgagaata aggataaaat gacgtttaaa cattatatct ttgaaatttt
    23161 ccttccatgg tataagacac aggtaaagct cagaacatat gaaaatcgct taccaactat
    23221 taagaagcat ttctcttatt ttgataaaat ggctgtttcc gatattgagc ctattgatgt
    23281 gcaaaattgg caactaaaat tatcaaagaa gtgtaagtct tcttatgtaa gagctgttca
    23341 aggactattt tcagttgcta tggatcgagc aattgtcctt gggataacca ccacaaatcc
    23401 atctaagatt attggcaatg tgaaaaagca aaagtctaaa attgaatttt ggacaaaaga
    23461 agaatttgaa aaagtaatct ctctaattta caaagaagat tactatcaac actttttatt
    23521 tatctctctg tggtttttat ttatgactgg aatgcgaatt ggtgaagcta ctgccattca
    23581 atgggaagat attgattttg actcaggagt actaaccatc aacaaaacac tctattacaa
    23641 gaatcaatcg aattatagat ttgttgaacc aaaaacaaag gcgagcgttc gtcatattgt
    23701 attagataaa tgcacattaa cttatttatc cgaatggaag gaagtacaac aaaatctaat
    23761 tcagacagac tttgtaatga gctataacgg tattcctacc caaaaacata cactatcata
    23821 tgctattgaa cgctatgcta agctggctgg tatccatcga atcagaatcc atgggttacg
    23881 gcattctcat gcttccttgt taatcagtat gggagaaaat ccacttatca ttaaagatcg
    23941 tctaggacac gaagatattg agacgacttt aggaacgtat ggacatcttt atcctaacag
    24001 taatttcgag gtagctaaca aattaaatgg agccatttcc tttaaagaag caaaacaaaa
    24061 ttatgatact tcaccaaaga atcaatttac tgtagactac ttgcgaaaca aagaaatgaa
    24121 aaaagtgcaa taaaagtgca gtaaaaagat aagaagagcc agaaaccctt ggtataagag
    24181 gatttctagc tctcctacaa ctattcccac tccactgttg ctggtggttt agaagtgatg
    24241 tcatacacga tacggttgac gtgggctact tcgtttacga tacgtacaga gattttttgc
    24301 aagacttccc atgggatacg ggcaaagtca gcggtcattc cgtcgattga agttacagca
    24361 cggataccga ctgtgtagtc gtaagtacgt ccgtcaccca taacaccgac agagcggatc
    24421 cctggaagaa cagtgaaata ttgccagata tcacggtcaa gtccagcagc tgcgatttct
    24481 tcacgcaaga tagcatcaga ttcgcgtacg atttctagct tgtcttcagt gatttcgcca
    24541 agaacacgaa taccaagacc aggaccaggg aatggctgac gccaaacgat tgaatcaggc
    24601 atgcctaact gagtccctaa ttcacggact tcgtctttga ataatgtgtt taatggttcg
    24661 atcaattcaa attgcatatc ttctggcagt ccacctacat tatggtgaga tttgatcgtc
    24721 tgtgctgttt ctgtaccaga ttcgataacg tcagtataca acgttccttg tgctaggaaa
    24781 gagacgcctt cttcaccagc aagttttgtt gcttcgtcat caaaaacata tacgaattca
    24841 ttcccaatga ttttacgttt ttgttctggg tcagatacac ctttcaactt gtctaagaag
    24901 cgatctcttg catcgacttt gatgatgttc aagccgaatt ttccgcctag actttccatt
    24961 acttgttccg cttcgccttt gcgtagcaga ccgtggtcaa caaagataga tgtcaattgg
    25021 tcaccgatcg ctttttgtaa aagaacccca acgacactag aatcaacgcc acctgaaaga
    25081 ccaagcaaga cttttttgtc accaacttgt tcacggattt tttctacttg catatcgata
    25141 aagttatcca ttgtccagtt accttcacag tgacaaacat caaaggcaaa gtggcgcagc
    25201 aattcgattc cgtattcgga atgacgtact tctgcatgga attggatacc ataaaaatta
    25261 cgtgttgtgt cttggataga agcaatcgga caatctttgc ttgttccgac tgtttcaaag
    25321 ccttcaggaa ctttagttac caagtcacca tggctcatcc atactgtttg ttgttttggt
    25381 gtttctttaa acaagacagc ttgatcgctt gttacttcta acaaggcttt cccatattcg
    25441 cggtttttag caggctctac ggaaccgcca agtttgtacg tgatcaattg cataccatag
    25501 caaatcccta atacaggaat acctaaattg aagatctcag gatcgatccc aaatgcattc
    25561 tcatcatata cactgtttgg tccgccagaa agaatgattc cctttggatt catcgctttt
    25621 acttcttctg cagtaatgcg gtggctcaat aattcggaaa agactccaag atcacgaata
    25681 cgtcttgtga tcaattggtt atactgacta ccgtagtcta atacgataat cttttcaacg
    25741 ttcgtcatat cggcaacgtt tgtcaaattt attaccccta tccctttaaa ttttatctca
    25801 aaatagtcaa actattttaa aatgctaata ttttcgcatg aaaatcgaat cgatgatatg
    25861 attttcagtt ttatggagaa ttatatcggc tcttcctcgt gtaggcaaga tatattcctg
    25921 taaatttttc aaattcacat ttttccatac atcttttgcc attttaaagg cttcttcacg
    25981 atctccgata gcaaaacgat aataataatt ctctggattt tggaaagccg tatccagtaa
    26041 cgcaccaaaa cgatccaaat accatttttc gatcagcacg ggatcggcat cgacatagac
    26101 agaaaaatca aaaaagtcgc tgacgtagat ttgctgattc gcaggtaatt gaagcgtatt
    26161 gatcccctca acgatcaaga tatcaggctg ctggatcaat tcgtacttgt ctggaatgat
    26221 atcatacaca tcatgtgagt aaacaggtac ttttatctct tcctgaccag attttacacg
    26281 gttcaagaaa tcgatcagca tctccatatc ataactttca ggaaatcctt tacggtccat
    26341 gattccacgc tcttttaata tacgatttgg ataaagaaat ccgtcagtcg tgatcagctg
    26401 aacgtttctt cgtttgaagg tacgagacaa aatcgtctgc agcagtctgg ctgttgtact
    26461 ttttccaacg gctacacttc cggcgatccc gataataaaa ggcggtactt ctacgtattt
    26521 atgaagaaat aaacctttac tcaagaacaa agattcaaat tctttcatat aaagataaat
    26581 cagatgagca agaggtacat agatatctcg aacatcctgc atggaaatgc ggtcattcaa
    26641 acttttgata ttatctagtt catcttgtgt caaaggtgct tgcccattac gataaaattc
    26701 tcgccattct tctcttgcca cacggtagta gttcattgga tcattcatat tagcctcctg
    26761 cgttctccca tcaatggaac tattttaaca caaaataaac gcaaacccca ccacttaaga
    26821 gagattgccg atctttttgt ataatcttta taatagaaag aaacggagtc ttattcttga
    26881 cttgcgcacg gatacataaa aggatagact gttgtcatga aagaaatgag aaggatggaa
    26941 gacatgacaa atcattacta ttctgaacgc ccagatacgg cgcacgattt tgaacaatgg
    27001 gcttttgagt taaaaggcag aacctttcaa tttgtaacag attctggtgt attttcacgt
    27061 gaaacagtgg attatggttc acgtgtcctg attgatgctt tcgattggga agagttacct
    27121 gatgaaggaa agatcttaga tgtgggatgc gggtatggac cgattgggtt agctttggca
    27181 tttgcgacac agcggtttgt tgaaatggtc gacattaatg aacgagcggt aagtctagcg
    27241 caaggaaacg caaagcgtaa ccaaatcgaa catgttgata tccatcaatc gaatatctat
    27301 gaagcagttc atgaagaaac ctatgcagct atcgtaagca atccgccgat ccgtgctgga
    27361 aaaaaagttg tacatgaaat tttgacaggc gcatatcctc ggttgaagaa gggcggtaca
    27421 ctgacaattg tgatccagaa gaaacaagga gcgccgagtg cgcaaaagaa aatggaagaa
    27481 acatttggta atgcagaaat cgtcacaaaa gataaaggat attatatcat caaaagtgtg
    27541 aaagaataac tagctgaaaa atagggctct ttgtcaataa ggactgatgg gttgtacaaa
    27601 at
//
LOCUS       DAFEIE010000195        18009 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.guided.051, whole genome shotgun sequence.
ACCESSION   DAFEIE010000195
VERSION     DAFEIE010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.guided.051"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..324
                     /locus_tag="LP345_002934"
     CDS             <1..324
                     /locus_tag="LP345_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL1761639.1"
                     /translation="SRGILELLREGQQGVTLRTFESMYFQKKLVTDNQAIAHYHFYRP
                     ENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKRFITNDSTIYEQYEYDLS
                     SVENK"
     gene            complement(474..1415)
                     /locus_tag="LP345_002935"
     CDS             complement(474..1415)
                     /locus_tag="LP345_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL1761640.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1541..2662
                     /locus_tag="LP345_002936"
     CDS             1541..2662
                     /locus_tag="LP345_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL1761641.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2920..4422
                     /gene="eat(A)"
                     /locus_tag="LP345_002937"
     CDS             2920..4422
                     /gene="eat(A)"
                     /locus_tag="LP345_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL1761642.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4450..5016
                     /locus_tag="LP345_002938"
     CDS             4450..5016
                     /locus_tag="LP345_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1761643.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            5227..6288
                     /locus_tag="LP345_002939"
     CDS             5227..6288
                     /locus_tag="LP345_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL1761644.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6291..7187
                     /gene="murQ"
                     /locus_tag="LP345_002940"
     CDS             6291..7187
                     /gene="murQ"
                     /locus_tag="LP345_002940"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL1761645.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7201..9183
                     /locus_tag="LP345_002941"
     CDS             7201..9183
                     /locus_tag="LP345_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1761646.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9248..9694)
                     /gene="nrdI"
                     /locus_tag="LP345_002942"
     CDS             complement(9248..9694)
                     /gene="nrdI"
                     /locus_tag="LP345_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL1761647.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            9905..11329
                     /locus_tag="LP345_002943"
     CDS             9905..11329
                     /locus_tag="LP345_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1761648.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(11510..12283)
                     /locus_tag="LP345_002944"
     CDS             complement(11510..12283)
                     /locus_tag="LP345_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1761649.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12280..13185)
                     /locus_tag="LP345_002945"
     CDS             complement(12280..13185)
                     /locus_tag="LP345_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1761650.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13339..13659)
                     /locus_tag="LP345_002946"
     CDS             complement(13339..13659)
                     /locus_tag="LP345_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL1761651.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            14133..14819
                     /locus_tag="LP345_002947"
     CDS             14133..14819
                     /locus_tag="LP345_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL1761652.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            14821..15765
                     /locus_tag="LP345_002948"
     CDS             14821..15765
                     /locus_tag="LP345_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL1761653.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            15964..16608
                     /gene="pcp"
                     /locus_tag="LP345_002949"
     CDS             15964..16608
                     /gene="pcp"
                     /locus_tag="LP345_002949"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL1761654.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            16687..17964
                     /locus_tag="LP345_002950"
     CDS             16687..17964
                     /locus_tag="LP345_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1761655.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         5752 a         3195 c         3847 g         5215 t
ORIGIN      
        1 tcgcgcggga ttctggaact gttgcgggag ggtcagcaag gagtgacttt gcggacattt
       61 gaatccatgt attttcaaaa gaaactagtg acggataatc aagcgattgc tcattatcat
      121 ttttatcgtc ctgaaaatat ttttttgctt cgagaacgtg atttagatga attaccggaa
      181 tttctgcata caccatttaa gccaatccta tcagagctat tggaatttta tgatgcagaa
      241 aattgggcaa aacgatttat cactaacgat tccactattt atgagcaata cgaatatgac
      301 ctctcctctg ttgaaaacaa ataaaaaacc tacattttga agagattatg tactgaaaca
      361 aacaagcaca attcttatgg catcatgaga gttgtgtttt ctttttgatc ttttattggg
      421 cttaaaaaaa gagaaccagc tgctgattca gctgattctc atcagagagc cttttattct
      481 gcgccaagga ttccttcttt tgcatggact aattgggtca aaaaggcaca atatggtgta
      541 gcaatatcat atttttgtcc ttttcgccaa atggcaccat tgatgtagtc gatttcagtc
      601 aaacgatggt ttttgatcag gtcttggtac atagatgggt aatgcaaccc gatgttgtca
      661 ggatcataag tagaagcaat atgttggtac acttcttctt gatctagtat gattccttct
      721 tttgctgcga tagaagcaaa ttcagatacg attgttcgaa ccatgctctc tgccgctttt
      781 tgcgcgccta gttcagcaat attacaatcc aaaatcgtgc ataaaccatt caatgttcca
      841 tttacacaag cttttcgcca aatggaataa cgaacgttat ggctatagat cggatttaaa
      901 tttgcttctt gaaagacttc tacaactttt tttgtaaatg cttcgccttc tggttccaag
      961 ttctctagtt cgatttctcc atcacctaac aatgtgactt ttccgggacc agctagacca
     1021 gctgtccaca tcgtgatccc aaataagata tttttctttg gcacatattt ttccagtaca
     1081 tcttcatgac ctaatccatt tagtaaacac aaaacataag tattgtcagt aataatggat
     1141 tggatcgaac aaaacatatc atctaattga ttggcttttg ttaatgctac gatcaagtcc
     1201 acgtgttcgt tgctttcgat gatttcttct ggtgaataga ttggcagttt tgcgaccact
     1261 tctttaccgt taaagtcagc aatcaaccca tttgtacgaa tggcttcaat gtgagcaggc
     1321 caacgatcga tcaagaggac ctcatttccg ctttgatgta gcatcaatcc gattcggctg
     1381 cccattgctc cggccccagc tattgcgatt ttcatgtttt ttctctcctt tattcaatga
     1441 gttccctttt agtatataga aaaatggaag aaaatagcat tgttttgttt gaaaaaaatg
     1501 aaaaaaagtg tcttacttaa gaagaaagtg agggatacag atggatattt tggcggcaat
     1561 tgattcattt aaaggaagtg cttcttcatt tgaactaaat caggcagttc taaatggctg
     1621 ggaagatcgt aaaggaagaa aaatcaatgt gccgattgca gatggcggag aaaatactgc
     1681 agaagcaatc tattacgcgc tcaggggaac atggcgtacc attgatggga tggatctctt
     1741 attccgtcag cgaaaaatca gctatttatt gacaacttgg caaggaaaaa acaccgcagt
     1801 catcgaatct gcacaagcat tggggttaga tctacttgat aaaccaacgg atcaaactat
     1861 ccgacttgct tccagttatg ccttaggaga acttattaaa gatgcactgc ttcaagaagt
     1921 agaacaaatt attgtcactt taggaggaag cgggtgtagc gatggtggtc taggattact
     1981 ccaatccttg ggtgcttctt tagaagggta cacagaagga aatcctttat tatctactaa
     2041 aaaacttcat tttgatcgaa gaaacgttct tgtttctaaa gtaaaattga ttatcgctgc
     2101 agatgttacc aatccatata caggtcaaca aggagctgct tggcaatttg gaagacaaaa
     2161 aggaggaata gatacgacgc tagctttctt agataaacaa gcaggaaaga ttgctcagca
     2221 aataaaagat ttctgggagg tggatttaga tgatattcca ggaagtggag cagcaggcgg
     2281 tattggtgga gccctttttt tgttgggagc gaagatggtt tctggtttcg atttagtcag
     2341 ccaaatcact ggattggaaa aaaagatcga acaagcagat gtcatcatta caggagaagg
     2401 gcggatcgat cagcaaacga tccacggaaa agttccatac ggtgtagcag tgcttgcaaa
     2461 aaaatatcga aaaccaataa tcgctatttg cggaagtaga gaccaagagc tagaaggact
     2521 ttctgatttt ctcccaattg tcttaagtat tcatttgggt ccaataggtt tagaagaagc
     2581 aatggaacac aggcaaacat tagaaaaaac aaaaatctta ggacagacac ttagcagatt
     2641 tttcaccatc ctcccgaagt agttgacaaa atcattttct ttatgctatc gtaatttcaa
     2701 atataggaca aagtgaggga tccgtgcatt gaaaaattaa gtcgattgat gaaagctgca
     2761 ttcagactgt accttgtgga gacaaggaag cagtgtgcag attttcggga ttggcttggt
     2821 tttttcgatg tatgggtctt tttgtgtgta tccaaccctt gcatcctctt tagccagttc
     2881 tgaaaatagg actggtcttt ttttacgagg tgatggaaaa tgtctaaaat cgaaataaaa
     2941 aatctgacat tcggctacga cagccaaggc acattattat ttgaacaagc aaatctaaat
     3001 tttgacacac aatggaaact aggacttatc ggacgaaacg gtcgaggaaa gacaacttta
     3061 ctgaatattc tacaaaacaa actaccttat caagggcaag taatccatca gcaagaattt
     3121 gcctatttcc cgcaacagac aaaagataaa gaacgtttaa cctattacgt gttaaatgat
     3181 attacggatt ttgagatatg ggaaatcgaa agagagctcc aattgatgca aacagatcct
     3241 gaaatcttat ggagagaatt cagcacacta tcggggggag agaagacaaa agtcctactg
     3301 gcacttttat ttgtggatga cactcatttc ccgttaatcg atgaaccaac gaatcatttg
     3361 gatatctctg gtagaaaaca agtagcggct tatttgaaaa agaaaaaaca aggcttcatc
     3421 gtggtcagcc atgaccgggg atttatcgat gaagtagtgg accatgtttt agcaatcgaa
     3481 aaaagtcaac tggaacttta tcaagggaat ttctctatct atgaagaaca gaaaaaactt
     3541 cgtgatgaat ttgaaatggc tcaaaatgaa aaattgaaaa aagaagtcag taggctaaag
     3601 aaaacagcag ctgaaaaagc cgaatggtct cgttcccgag aaggagataa aacaaagaaa
     3661 caagtcggat tcatcgatac tgaatctaga cgagtgaata aaggagcagt gggtgctgat
     3721 gctgcacgga cgatgaaacg atccaaagca atcgtgaatc ggatggagac ccagatcagc
     3781 gagaaagaaa aactattaaa agatatcgaa tatatcgatt ctttgacgat gaatagccaa
     3841 gcgtctcacc ataagcgact tttaagcgta gaagatcttc aattagggta tgaaaatctg
     3901 ttattcgagc caattcattt tacaatcgag cctcatcagc gggtggcgat ttcaggtcct
     3961 aacggtgcag gaaagtcatc cattatccat tatcttctgg gggcattcaa cggcaaggtt
     4021 ataggagaaa aataccagcc aaaacatctg agcattagtt atgcaagcca aaattatgaa
     4081 gacaatcgag gaacgttggc ggaatttgca gagaaaaacc aagtagacta ccaagcattt
     4141 ttgaacaacc tccgaaagct tgggatggaa agagatgttt ttcataacaa gatcgagcag
     4201 atgagtatgg gccaacggaa aaaagtggaa ttggctaaat ctttatcaca gccagctgaa
     4261 ctatatacat gggatgaacc attgaattat ttggatgtct tcaatcaaga acaattagaa
     4321 caactgatct tgaacgtgaa acctgccatg ttactagtgg aacatgatca aaccttcctg
     4381 gataaagtat ctactgagat tatttctctt gagagaatct aacccttgta atctcaagaa
     4441 caacaaggta tggttaaggg gaactttgcc aacgaaggag agaatcacat gctttatgta
     4501 acgagacacg gagaaacaac ttggaacgca caaggattag tttgcggacg ggcagatgtg
     4561 ccgctgactg aaaaaggaca gatgcaggca cagaaactag cagaaaaggt agtagatttg
     4621 cctgttccaa tcacgaaaat catccattcc cctcttcaac gagcaagaga tacagcacaa
     4681 gcagttgctg atcgtctcag cttgccgctg accgttgatg aacgattggt agaaatggat
     4741 tttggggatt atgatggact gccaagcaaa gatgagaact ttcaaaaagc acgtttagcg
     4801 ttcgctgtac gattcccaaa tggggagtca gtcttagatg tgtatgcacg gatcgttcct
     4861 ttattgaaag aatgcatcga agacgaagaa aatgtctatc tgttagtttg ccataatgcc
     4921 ttgataagag tgatcaatgc ttattttcat ccgatgccta atgaggggtt ctttacattc
     4981 atggtagata atacagaatt ggtttcttat gagtaattat gtttttgtgt tatttaaata
     5041 aaatatttca aggcactgct tttgcttagc agtgcctttt ttaggttatg acaattcttt
     5101 tgataatata aactcaacct ttagaaatga aatttaatta ttttaataaa agtattgaaa
     5161 ttttgtttct ttagatatat actctagtca tagaaatgaa gacggataca gaaaaagagg
     5221 gataatatgt ttggcttttc aatatttatg aacgattctt tgtcagaaga gaagaaacag
     5281 tatatccgcc aaatggcatc caatggcttt gtcggtattt tcacttccat gcatatacca
     5341 gaagatgatg tttcggcata tcaaaagcga ttgatcgaac taggaagcga agcgaaaaag
     5401 aataaactag aattgatggt cgatatttca ggagaggcat tggaacgagc gggtttttca
     5461 ttagaagatc taacgccttt gaaagcaatt ggtgtaacag gtttaagaat ggattatcat
     5521 atttccaatc agcagattgc cgactggtca catcaattga aaatcagttt gaatgctagc
     5581 acgatcacgc ctaaagatat cgatgaattg aaagaagcag aagctgattt ctcacagatt
     5641 gaagcttggc ataattatta tccacgtccc gaaacagggc tggacaaaga atggtatcag
     5701 aaaaaaaatc aatggctcaa aattcaaggt ctccttgtcc aaggttttgt accaggagat
     5761 acagagttga gaggcccact atatcaagga ttgccaactt tggaagaaca tcgagggatc
     5821 catcctcttg caggcgctct agatctatta gcaagtaaca cggatattgt ttacatcgga
     5881 gatgcaggtc tgtcagaaaa cgttcaggag caatttgctt ctttccaaaa agaacagaca
     5941 gtcttgctcc atacggaacc tgtagatgaa gaattttacg aatatatatt agggaagcat
     6001 acgaatcggc aagacgatgc aagagatgtc atacgaagcg tagatgcacg ttttcgagag
     6061 attccgccta tcccagcaag aaatacagct acgcgtatga aagggtctat tactttagat
     6121 aacgaaaagt atttgcgcta tatgggtgag atccaattaa ccaaatatga tttgccagcg
     6181 gatgaaaaag tgaatgtagt agctaaagtt atcaaagaag agctaccatt gatcaaccaa
     6241 atcaaagctg gtatgaacta tcaatttata agaaaagaag gaagataaaa atgagcaaaa
     6301 tcaatttaga gaacctaaca acggaacgca gaaaccaaga aacttttgga ttagatgaga
     6361 tgagtatttc tcaagccgtt caactaatga acaaagaaga tcagaaagtg gccgctgcgg
     6421 ttgaaaaaga actgacaagt atcgaaccag tgattgctaa cacgattgag tcctttaaaa
     6481 aaggtggacg tctgatttat atgggagccg gaacaagtgg aagactaggt gtgttagatg
     6541 ctgctgaatg cgtaccgaca ttcggtgtag aaccggaaat ggtcataggt ctaattgctg
     6601 gtggagaaga agcaatgact gtagctgtcg aaggggccga agattcttat gagctagggc
     6661 aagaagatct aatcaagctg aatttgacaa aaaatgatat agttattggt atcgcagcta
     6721 gcggtcgtac accatatgtg atcggtggat tagattacgc aaaatcgatc ggtgctgtca
     6781 caggaacgat ttcttgcaat aaacaagccg aaatcagtaa acacgcggat ttcccaatcg
     6841 aagtcgatgc aggtccagaa tttttgacag gctctactcg attgaagtca ggaacagcac
     6901 aaaaacttat cttgaatatg atttctacta tcagtatgat tggtataggt aaagtattca
     6961 ataacttgat ggtcgatgtc aaaccaacaa atgaaaaact aatcgaacgc tcaaaacgaa
     7021 tcatcatgca agcgacagaa gctgattacg aaacagctga aaagtacttt gaagaagcag
     7081 atcaaaatgt taagctggct atcgtcatga ttttgacaaa tagtgataaa gaggaagctc
     7141 aagcaaaatt agctgaagca aacggatttg taaaagggac cttatgaggg ggaaaagacc
     7201 atggcaaaaa acgaactgac tttggaagaa ctggcaaaac aaatttataa aggggcaggc
     7261 ggcatgggca atgtagaaag cattgtccac tgcatgactc gtgtgcgtat gaagatcatc
     7321 aatgatgatc ttgtaaatgt ctctgaatta aaagcgattc caggagtgct tggtgtagta
     7381 gaagatgaac agcttcaagt catcatcgga cctgggaaag tgaacaaagt agcacagcaa
     7441 atggttgatt tggcaggcgt gaaattagga gaaaaacttt cttctgtaag tacagctaca
     7501 gcaaattcat cagcatctgg aaaagaccgt gtaaacgaac gggcacaaga aatgaaagcg
     7561 gcacaaaaat cgaaacaaaa accatctaaa atcaaatcgg tattaaaaga catttctaat
     7621 atctttgtgc caatgattcc tgcatttgtc ggtactggga tcgtggcagg gattgccgca
     7681 gttttagcaa acttagtcac agccggaaca cttgatgcag caacatggca acaatatatc
     7741 gatgtgatga acatcttgaa aaacgggatg tttagctacc tagttatcta tacaggtatc
     7801 aatgctgcac aagtttttgg tgcaacacca actcttggtg gagttatcgg ggccgttgtg
     7861 atgctgacag ggatgaatcc ggaagcacca ctgaaaaact tatttactgg tgaagctctt
     7921 gcagctggac aaggtgggat cctaggtgtc atcttcgctg tttggctatt gtcaatcgtt
     7981 gagaaaaaac tgcataaagt agtacctgat gcggtagata tcatcgttac accaactctt
     8041 tcgttgattg ccatcggtct gattgaaatt ttcttcatca tgcctttagc aggtttcatt
     8101 tctgatggca tggtcggtgg gatcaactgg gtacttggcg ttggtggagc atttgccggc
     8161 ttcgttctag gcacattatt cttgccgatg gttatgttcg gactgcatca aattttgact
     8221 ccaatccatg tgcaaatgat tgatgaaact ggtcgtacgc tattgcttcc aattcttgcg
     8281 atggctggtg caggacaagt gggtgcagca ttggcattat ggattcgctg caaaaaagat
     8341 aaagaattaa cagaaatgat caaaggagct ttaccagtcg ggatcctagg aatcggcgaa
     8401 ccattgattt acggagtaac attacctcta ggacgcccat ttattactgc ttgtatcggt
     8461 ggaggtatcg gcggggcagt gatcggaatg atcggaaatg tcggggctat cgctattgga
     8521 ccttcaggag ccgctttgat cccattgatc tctgacggta aatggttagg ctacatcctt
     8581 ggattattgg cagcttatgc tggtggcttc gttgctacat tcttcttcgg tattcctaaa
     8641 gaccgtttag aaaaagaaga attagcgact gaaacagcca cagtaaatga agtgcctgaa
     8701 aaagtagtac ctcaaacttc agctgaaagt gtgactatcc tctcatcagt tgctgacgga
     8761 acagttgttt ctttagataa agcaagtgat ccagtttttg cacaaaagat gatgggtgaa
     8821 ggctactttg tagaaccaga aaacggacat atctattctc cagttactgg ggtagtcagc
     8881 tctgtcttcc caacgaaaca cgctattggg atcacaacgc caaatggttt agaaatcttg
     8941 cttcatatgg gaatcaacac agttgactta ggcggtacgc catttgatgt gaaagtaaca
     9001 gaagggcagc aagtgacacc tgatacgctt gtagcagaag ctgacttaga agcgatcaaa
     9061 gcagcaggca aagaaacatc catgatcgtc ttggtaacca atatggatcg tgtaaaaaac
     9121 tttgtcttgg aaaaaacagg taaagcaaaa gcaaaagcac ctgtgatgga tgtcaaagct
     9181 taatatgata gaaacaatag aaacgaaaga agaaactgaa atctattttt cagcttcttc
     9241 ttttttatta tttattgttt tctgctaaaa tctgataaat tcgtgtcaca tcagatggtg
     9301 ttccccgtaa ttcataatct gccaagaaag gaaagccaaa tgtttgtgca tattgtttgg
     9361 ctgttagaca atactgatta ttgaagtttt tatttccgct accgactaca ccaagacaaa
     9421 gtttatgatt gtcttcatgt tccagatatt cacgcatcgt ttcggtcaag atttctgtat
     9481 caccgttatc taaaccattt ccgccgtcta aataagtagg aacgaaagta aaaaatggtt
     9541 ctgtttcttt cgtaaaatca ctattttcat ggatttcttt taaagtaact tcaggattga
     9601 caggatcttc tgcatgcatt ttttcagcat attctgctag atgtttggca aaggcacgcg
     9661 tatttcctga aatcgatata tataaaatgt tcatggatca tcctccaatt ctttcctttt
     9721 agtatagcat cttttttaag ttttttggtg gtgtaatttg gaaagggact aggcgctttg
     9781 cttgtataat gagaaaaaag ccggtagaat tatatttcta ttaaagtttt tattaattaa
     9841 gtaaaaataa aaaaggtttg ttatactttt tgataaaagc ggttttattt tggaggatgc
     9901 ttacatggat acagagcaac agaaaaaagg aattggttta attccacttg ctgccttagt
     9961 aattggttca gcgattggag gtggcgtatt tggtattatg acggacatct ccggatcggc
    10021 tggcggccca gctattttca gttgggtact cgtaggaaca gcaatgttga tgctctcctt
    10081 gtcgatcaat aatatcaata aaaaacgtcc agatttaaaa ggcgggatct ttagttacgc
    10141 agaagaaggt tttggccgtt tcgctggttt tatcagcggt tggggttact ggctcacatg
    10201 ctggttaggc aacgtagctt ttgcaacatt gttgatgagc gcattaggat atttcttccc
    10261 agtatttgaa ggtgggcaaa atctggcatc gatcgtgatg agtacagtct ttttatgggg
    10321 atatgcatgg ctagtgaatc ggggagtcga aaatgctagt ttcgtcaatg ctatcgtcac
    10381 attctgtaaa ttagtgccat tatttttatt tattgtagta gctatcagca cgttttcgat
    10441 ccaacaattc attgataact tttctagcga cattatattg aatgcgaatg gacagccgat
    10501 cccgttttcc agtcaagtat tgagttgcat catggtgatg ctttgggtat ttgttggtat
    10561 tgaaggagcc tctgtcgtag gttcacgagc aaaaaaacaa tcagatgttg ggaaagcaac
    10621 gattctaggg atattcggct tgattattat ttacgtcttg gtttccatgc ttccatatgg
    10681 gacaatgacg atgaatcagc tgcaaacgat caaggcgcag cctgctatgg gctatgtgtt
    10741 tgaaatgatg gttggtaaat ggggagcagt cgtgatcaac ggcggtttga tcatttcttt
    10801 agttggtgtt tggctctcat ggacgatctt accgattgaa acaatgggaa acatggctga
    10861 agacggactt ttgcctaaag catggggaaa actcaacaaa aatggggcac caacttatgc
    10921 tatcgtattg acgacgttat gtacgaatgt ctttttactt tcattattat tcactgacag
    10981 tgcttataac tttgcttaca cacttggtac agcagctatt ttcttcacgt ggcttttctt
    11041 aggattgtac caaatgaaac tttcttatca gcggaaagaa tgggtccaat ttttagtagg
    11101 gcttttagca agtgcctttc aagtatgggc tatgctagtc gtagccttta atgaagtaat
    11161 gcttgttctt gttcttttct tgccaggcat ttatttttac ctcaaagcac gtaaggagca
    11221 aaacgagcct gtacaacata tccacttaga taagatttta cttataggtg tgacgatggt
    11281 cggagtgatt gcaatggttt tatttgccac tgggatgctt cacgtataga agtataaaag
    11341 aagtataaag agaggttgtg agcctgtcgt ttattcaaaa acatactagg aaaggagctg
    11401 tgacacaaat gttgtcacag ctcctttttc agaataaacg gtgtttaaga gacagccaat
    11461 cggcaataag gctgaacgtc tctttcacag cctctttttt gatgagtcat catacatttt
    11521 ttcgcttaaa tacgagatat cctaatgcta agaacaaaac gatgtaagct aaattaccga
    11581 atagcatttg attagtagaa agatgagtca attgcttcat gatctcttcg tttccaattt
    11641 ggttttgcag attcaacata ctgatcggat tccatttgat ccactcccat ttttggatga
    11701 gtgcaataag gataccagat atgattgacg aagcaaaata aaagacgatt cctgctgaga
    11761 tggatgcgcc ggaactattg ataaagcaag caatcatcaa cactaaactt aaaatcagcc
    11821 ataaaccgat ataactaccc aaagtataag tgaacaagct ttggatcagt gtttgaccag
    11881 tagaaacctt ctccgtgaag gaaatcgaag ggaaaagaat cagtttcatc aacacagtga
    11941 caataatagc taaaaggtat aaataaacag aataaataac taatgtgatc catttgctta
    12001 ctaatatttc tcctcgagaa tactttcgat aaaggagatt tttcaatgta ccatattgtg
    12061 cttccatcga aatgatcgtg cttgcagctg caatcatgat aaagacaatc caagatgtgg
    12121 cactaaaaag ctgagcagtc atttcaactg gatcaatgat cgtcgtgtat tttttggcta
    12181 gaagtgctgt tcctatgagc aaaacaacta atagaacaga taaaacagca gttgactttt
    12241 tcttgatcaa tttaaataat tcttgtttta caagcaatgt catttttctt cttccccctt
    12301 tactgaatcc agaatttcca atagagaaga ttccaaatca ttcgtcagat gctggacgtc
    12361 tgtcacatgg atattttgtg cagacaatag ctggatcacg gttcctaata attcttcgtt
    12421 ttcttttaaa agcttgattt tatcaggatc ttccaaagta tatccagctt ctgtcaagat
    12481 cgttcgagca gctagatcat ttgttgtaga gataacgatg aaatcttgcg ctgtttggtt
    12541 caattcagcc attgtacatt gtttgatgat ctttccttga ttgatcagga tcagctcatc
    12601 gaccattttt tcaagctcgc tgagtaagtg actggagatc aagaaagagg tgccctgagt
    12661 agccaagtcg gtaatgattt ttcgcacatc tcttgttgct tgtggatcca aaccgttcat
    12721 cggctcatct aaaataacga tagacggatg gttcagtaag gcaagagcaa ttcccaattt
    12781 ttgtttcatt cccaacgagt aggatttcgc ttttttgtga atgtactttt ccatcttgag
    12841 ctgattcacg atagtgtcga tagcagatac atcgttggtt tcagagaata acttcagatg
    12901 atcatagcct gttaagaatg gatagatacc cgggtattcg atcaatgctc ctacttgttc
    12961 caacccttta tgactagagg gagaaatctc attttcacca atacagattg ttccatctga
    13021 gtaatggatc agtcctaaaa tagctttcat gatcgttgtt tttccagcgc cattaggacc
    13081 tactaatcca acgattttgc caggggataa gctaaaactg acatcgctga gggcttgttt
    13141 gtgaccaaag ttcttggata attcttggac cgaaagactt ttcaaaaata ttcactcctt
    13201 ttctatagat agtacaagca tacacctgat gagtggagaa gtcgctaggt cattggactt
    13261 atttcttatt ttttcataaa aaaattgaat attaaataaa aaggcttatt ttttctgatc
    13321 agtacttatt ccaagtgtct agtggccgct agtaatcttg atgccaatga tactgatgag
    13381 tagcatcccc acaaagaacc aagtggaaag attcagctta tcatgaaaca agaccacacc
    13441 aattatgacc gaaccaactg cgccaatccc tgtccagata ggataagaga gactcatcgg
    13501 caaacttttg attgcctttg acaaaaagta aaaactagca atcatgccaa tcactgtgta
    13561 aaaagaataa ttgattttag aaaaaccatc actccatttc atcatcgttg accagaatac
    13621 ttccaaaatt cctgctatga ttaattccat ccatgccata cttacattcc tccttaacta
    13681 taaaaaaata cacaaaaaga ggaaaatcat cccttcaaag acctaatgga atgatcatcc
    13741 tctttatcct acccggtggc agattgtata tctttttctg tagtatagca cacctatcca
    13801 gatatcggca atctcatact ttttagtaaa gtgtaccaag cactgacgga tatatcgtta
    13861 gcggaaaaga agatgaatgc tttgcaattt catagaaaga agttgttatt tattaatcat
    13921 ttaaaaaaaa cagtaactag accttatttc tatatattat cgggcaataa attaaaaaaa
    13981 gctttacctt acaataagta agataatttt tgtgataaaa aaataacgaa aaatatttaa
    14041 aaatagtgtc tatttcgtga gaaaacaact atatttttta tgtgttttgc tttataatta
    14101 aaaaaatatt gtcattttat ggaggaaaat atatggaaaa ttatcttagc cttttaggcg
    14161 tcttgattgt tattctcggg tttgcattta aattagactc gatattgatc gtaatggttg
    14221 ctttagttgt tacagctttg actggcggtc ttggcattca aggaatgtta gaacttttag
    14281 gtacaagttt tgtaaacaat cgcgggatgg cgatttttat catcattatg ttggcaacag
    14341 gaacgcttga aagaaatggt ctgaaagaat cagcggcttc cttgatcaag cgattcaaga
    14401 aagtatctgc tggtatgatt gtagatattt atgggatctt tcgaatgatc tttgcggctt
    14461 ttaacgtgag ttttggtgga gttgctggat ttgttcgtcc aatcatttta ccgatggcat
    14521 tggggaccat cgaatcaaaa gggttagaag tccatcctaa gcatgaagaa gaactaaaag
    14581 gtatggcttc agctatggaa aatgtctgct ggttctttgg ccaagtacta ttcatcggag
    14641 gagcaggggc gttgctagtc caatcaacac tgaaagatct aggatatgac gtaacattgg
    14701 gacagcttgc tttagtggaa gttccagtgg ctatcacggc tttagttgtg gcaagtgtct
    14761 acttctatct taaagaaaag aaattagcga agaaatatta tccaggaaag gggcaataag
    14821 atggactttt ttacaaatcc tgatatttta ttaggcgata aattactgga gatcctttat
    14881 atcgtgatgg gactcgtatt gatttacact ggagtaagaa atttaacaga taaaaccaat
    14941 cctcatcgtt atgggtcagc ctttttctgg acggtcttag gggtagttat tgcaggagga
    15001 agatggcttc cggcaatcgt gaacggtggc ttgatctttg cgatgaccat accagcaatt
    15061 gctaagaaag tcagcaaagg agaaagccgg cttccatcaa aagaatatat ggaaaaaatg
    15121 tcagacaaac taggaatgaa aatttttatt ccagctttga gtatcggtgt ctttgcgatc
    15181 ttgtttgctc tatttaccaa tttaggtgct ttagtcggcg tgggcgtcgg tgtttttgca
    15241 gccatgctaa tcttgatgtt cttttctcga gataatcgac caagtacatt tttagatgat
    15301 gcagcagata tgctgggcac agtagggccg ttaagcatgt tgccaatgct tttagcttct
    15361 ctaggtgcgg tatttacaag cgctggagtt gggacagtga tttccaatgc agtaggtacg
    15421 atcgttccag aaggaaatgt gaacatcggc atcatcattt acgctcttgg catggtgata
    15481 tttacggtaa tcatggggaa tgcatttgcg gccatcaccg tgatgacggt tgggatcggt
    15541 gcaccattcg tatttagtca tggagcgaat ccagcgttaa taggaatggt tgcattgact
    15601 tgcggttttt gtgggaccct gctgacaccg atggctgcta acttcaatat cgtgcctgta
    15661 gcgatgctgg agatgaaaga caaatacgga gtgatcaaaa accagttgtt tattgcgtta
    15721 tttatgctag ttttccaaat tgcttatatg attctattta aataatagaa gagaggggtt
    15781 gtgacagaat aattgtcgca acctcttcta acattgtagt ggaacactat ttttttataa
    15841 gaatatatta agtttgatct gttatgttat ttaaactatt gtttccttta tttacgctgt
    15901 tcaaggaaaa tggtatgata aaagataacc atatgttaaa tcaatcggac ggaggaacaa
    15961 cagatgaaag tactagtaac aggttttgat ccatttggtg gggacaaagt gaatccagcc
    16021 tatgaagcag taaaaaaaat gccagatgaa atcagcggtg ctgaaatcat caaagtggaa
    16081 gtaccgaccg tattcgaaaa aagcagtcaa gtagtcaaag aagccatcca acagcaccaa
    16141 ccagatgtcg tgatctgtgt cggacaagca ggtgggcggt cagcagtctc gttcgaacgt
    16201 gtcgcaatca atctagcaga agcaagaatc cctgataatg aaggaaatca gccattcgat
    16261 acggctttag aagaaaacgg tccagccgct tactttacct cattgccaat caaagcaatg
    16321 acaaaaaatg tacaagatca tggtctacca gcgtacatct cttatacagc aggaacattt
    16381 gtctgcaatg atatcatgta tcgtttgctt catttgatcg aaacacaatt cccggcaatt
    16441 cgaggtgggt tcatccacgt gccattctca cccgatcaag tgatcgatcg tccagtgggt
    16501 acgccttcta tgtctttaga agacattgct tcttctttga cttatgcagt tgaagcagca
    16561 gtagaaaata aagaagatat ttccggaaat gccggaacaa ctcactaatt tagcaagaaa
    16621 cactggctgg ttgctaacgt tatgttagta gccagctttt tgtaattaga aaggaaagaa
    16681 acagccgtgg aagaatggca atccgtcttt gaagaatggt ttccaaaaga aatcagcaaa
    16741 agctatccca tcaaaatttc taaacaatac acaagcagtc aacgttggga gatctatgca
    16801 aaattaacga aaaaacagcg ggaactagtc gataagcacc gccgatatct aatcagctct
    16861 cgttttatgg aagaacatta tttagctgca acagattggg tgttttctga cttcaagatc
    16921 aatccgtttt ttcgaacaaa acgaagccag caaaaattgt attgtgagtg tggtagagaa
    16981 ttaaaagtgc aatacatcgt taaatcgcca aaaaccggaa agatcctaaa actaggcatc
    17041 aaccactttg ccgatcacct gcatgtctct ccgacagtgg cagcttcgat ccatcaggga
    17101 atgacaaaag ttgatctggc cttagacgaa ttattatggc ttaagcagaa gaatatcgat
    17161 tttcctgaag gactatggca aaaatactgt tttgtcttgt accaaaatcg tcggatgaaa
    17221 cagccatatt taccggatat aaaattagct cagcggctcg cagaatttcg ccaagtagaa
    17281 atgccgattt acatagcgga ttatcaagca ttggaaaatg aaatcaagaa aataagtgaa
    17341 cacatcaatg ggcagtcaaa aaagcgacag ataaaaaaag aactatttga cgactttgca
    17401 gaagaattag taaaggatgt agaagaattc ttgatcaact atcgcgcatt tttacgtaaa
    17461 gattggcaat ccatcgtata tgaagaagtg ccagtacatc ctaatgctta ttttgaaaca
    17521 tttatttccg tgttgagaaa gacaaaacgt caacgaacac cagaagtcac tgctcagatg
    17581 gaatattttg cgaaaaacca acgattcatc caaccaaaaa tctatctatt tatttggaag
    17641 caatattgtc actatggttt tacagaaggg ttcttcgaca gcattcctcg gatagtcaga
    17701 aatggttttt taaaagtatt gcgtaaagaa cgagaagcta tacaatctgc tgataagaaa
    17761 gaccgtacag tctcaaaaga aaaatggcaa ctagtagtga aagatatcca atctggaaat
    17821 gtgcaagaga caatcgacaa atggaaagga aaacattatc gttttactga agctcagaaa
    17881 caagcgttgg aatattatca gaagttagaa gaatcactgc gtttcaatga tgaggcaaga
    17941 aagtatctga aggaattact ataaaaaata gaggctggga cagaagcgtt taactccaag
    18001 aaataagaa
//
LOCUS       DAFEIE010000196        14956 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.guided.065, whole genome shotgun sequence.
ACCESSION   DAFEIE010000196
VERSION     DAFEIE010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.guided.065"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            complement(255..722)
                     /locus_tag="LP345_002951"
     CDS             complement(255..722)
                     /locus_tag="LP345_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBL1761656.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            845..1696
                     /locus_tag="LP345_002952"
     CDS             845..1696
                     /locus_tag="LP345_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1761657.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(1947..3905)
                     /locus_tag="LP345_002953"
     CDS             complement(1947..3905)
                     /locus_tag="LP345_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1761658.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(3902..4774)
                     /locus_tag="LP345_002954"
     CDS             complement(3902..4774)
                     /locus_tag="LP345_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1761659.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(5116..5988)
                     /locus_tag="LP345_002955"
     CDS             complement(5116..5988)
                     /locus_tag="LP345_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1761660.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            6116..6685
                     /locus_tag="LP345_002956"
     CDS             6116..6685
                     /locus_tag="LP345_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL1761661.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            6752..7489
                     /locus_tag="LP345_002957"
     CDS             6752..7489
                     /locus_tag="LP345_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1761662.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            7720..8988
                     /locus_tag="LP345_002958"
     CDS             7720..8988
                     /locus_tag="LP345_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL1761663.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            9475..9939
                     /locus_tag="LP345_002959"
     CDS             9475..9939
                     /locus_tag="LP345_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1761664.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            9923..10552
                     /locus_tag="LP345_002960"
     CDS             9923..10552
                     /locus_tag="LP345_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL1761665.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            10906..12384
                     /gene="msr(C)"
                     /locus_tag="LP345_002961"
     CDS             10906..12384
                     /gene="msr(C)"
                     /locus_tag="LP345_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL1761666.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            12431..12877
                     /locus_tag="LP345_002962"
     CDS             12431..12877
                     /locus_tag="LP345_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL1761667.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(13076..13591)
                     /locus_tag="LP345_002963"
     CDS             complement(13076..13591)
                     /locus_tag="LP345_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1761668.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            13708..14910
                     /locus_tag="LP345_002964"
     CDS             13708..14910
                     /locus_tag="LP345_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1761669.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4675 a         2711 c         3079 g         4491 t
ORIGIN      
        1 caaaaccgga aggttaaaac cctaactcta atatacaagg aaaaatggga aatagctttc
       61 catattttgc atttttcaga actaatgccg agggtcagct acttgaacac cgtttatcaa
      121 gacgtcatga cttcagcgct ttgacctgag cattagagag gaaaaagggg catgacaagg
      181 cttttgtccc ccggagaata aaagaattta tgtagacgat tccgatcaga aaaatgcagg
      241 cacagtagag agaattataa aaatctctct acgaggcctg tgttttctgg tcttttttct
      301 ttttccaaaa cggctatttt atgtatcaga ctatcaagtg tgatcttagc catttcttct
      361 tctgcctttt tctgcagccg agcgtagctt tcttctaaag cttcttggat attcgcacca
      421 acgacgcaat ttggatttgt ttttggatcg acttggataa gctgtgtatt accttcgatg
      481 ctgcgataga catctagtaa agaaatctga tctggacttt tggcaaggga aggctgcggt
      541 tttccggttt ttgtaaagat caaaccggat tttttgagct gactcatgat tttacgtaca
      601 tttgctgcat ttgtttcgat actactggca atcatctcac tagaaagtga tcgggtatct
      661 tgaaacattt caatataggc aagtacatgg attgcatcac taaattgcag agaatacttc
      721 atcagttgtc atcctttcat tttttttgct tgacttatct taccacactc tttatgataa
      781 aggtgtaatt tataaatgta cagctgtaaa tcttaacaaa taaaaagaat agggagtggc
      841 aaatatgcat tatttagtaa caggagcaac tggaggtttt ggtggttatg cgctggaatt
      901 cttaaaaaag atggttccac aaaatgaaat ctatgtacta gtacgtagtg aagaaaaagg
      961 agaagcactg aaagaagctg gatttaatat acgtattggt gattatgatg atttagactc
     1021 aatgaaagaa gcgttgaaag gaatagatcg attgcttttt gtctctggcg ttccaggaaa
     1081 tcgtcaagcc gaacataaga atgtagtgaa ggcagcacaa gcagctgggg tatcttatat
     1141 cgcttataca agttttgcag atgccgatca ctcgatcagt gtattagcgc cagatcacca
     1201 attcactgaa aaaatgatta aggattcagg tatttcccat acatttttac ggaataattg
     1261 gtatgtagag aatgaattac ctatcattgg gcaggcttta aaaactggtc aattcgttta
     1321 tgctgcagga aatggaaaaa caggttgggc attgaaacgt gaatatgcag aagctgcagc
     1381 aaaagtacta gtagaaagtg actctccaga aatcttagaa ttatccggca atctaactga
     1441 ctatgaagaa ttagccaagg cattagagcg tgcgacaggt aaagagttag aaattattga
     1501 agcaagtgat gcagcgtttg tcgaaaatct aaaagaagcc ggattccctc aagaagcagc
     1561 tgacatgttt ttagcgatcc aacatgatat taaaaaggat cagttagcta tttcctctga
     1621 tgatttagaa aaagtattgg gaaaaccatt aacttctctt gaagcagcat taaaagaaat
     1681 attggatcag gaataatgta taaagaggtt gtgaaaaagc cgattagttt tgagtatgaa
     1741 gaaaaatttt gtgaaaaagc tgttctgcat caagtaataa gaagagtcaa ataaaaaata
     1801 gctcttcata tgtttcgttt agctggactt attaccgcgg agttggcagg agaacgccgt
     1861 ttttattcgg aaaaaggagc tgagacaaga tttttgtctc agctcctgtt tgtttatcga
     1921 taaaaaagtc tggggaagac gatggctcag gctttgttgg aaacagagcc gattttatca
     1981 tttgctttta catcacgtgc gggttcgatt tctaagcttt ggactttgtc gccatttgtg
     2041 aatacaacga ccatatccgt gtttttgcct gcagattgaa tagcggcaag atcaactaaa
     2101 gcaatcaatt gacctcttgc gactttttga ccttcttcta catataaagt gaatggttcg
     2161 ccttttaagt caacagtgtt gatgcccata tgaagcaaga cttcgatacc agcatctgtt
     2221 tggattccga cagcatgttt cgttgggaaa atgtttgtga tcgtaccagc gattggagag
     2281 aagatttctc cattttctgg taatacagca tagccgtcac ccatcatttt ttccgcgaat
     2341 acatcatctg aaacttcagt gattggaatc agtttcccat ttgcgatagc gtaaatatct
     2401 tgttcgatcg tttcaccggc aaatgtttct gttttaacca cggtgtttgt ttgtgcaggt
     2461 cgtgctgcag caccaccatg tagttttgcc atctcatctg caacgaattg tacttctgta
     2521 cctacgatga cttgcgcatt ttttccgtcg atgatcttca taccaggtac gccagtggct
     2581 ttgattttat tttgatcgat caggcctgta tctttgactt gcaaacgaag gcgtgtagta
     2641 cagttatcga tcgaagttac attgtcggct ccgcctaatg cagcgtagat tttgcttgct
     2701 tgtgccgcat atttattgtc tgaattagtc gttgcagtat cgtcatctga aagatctgct
     2761 tcctcgcggc caggagtcat cagatggaat tttttgatag caaagttaaa gccaaagtag
     2821 taaatcactg ctgttactaa tccttggacg atcaacatca atggctgatt cgcaatcgga
     2881 tttttcaaag ataggaagta atcgacaaat ccggcactaa aggcaaatcc tgctgtccaa
     2941 tggaagaatg cactcactgc taaagaaatc ccagtgaaaa ttgcatgcaa gacatataat
     3001 ggccaagcaa cgaacataaa tgaaaattca agtggttctg tcacaccagt aaagaatgaa
     3061 gcaaaagctg ctgctagcat caaggaagct gtttttgctt tgttttctgg acgtgcattt
     3121 ctgtaaatag catatgctcc tgctggaagc ccgaacatca tgattgggaa aaatccagct
     3181 tgatacattc ctgttacgcc ttttgttcct tcagaagcca aaaatttacc aatatcattg
     3241 attcctgcta cgtcaaacca gaacacggag ttcattgctt gatgcaatcc tgtagggatc
     3301 agtaaacggt tgaagaagcc ataaagacct gcaccacccc agcctaaact caaaatgaat
     3361 ttagcaaaag aaactaaagc agagtaaacc ggaggccata cgagcagtag cactgcactg
     3421 atcagcaaca tgacaaaggc agccaagatt ggcactagac gcttgccgct aaagaaagat
     3481 aaagccatcg gtaattttgc ttcgtggaaa cgattataaa gagctgccgc aatcaatccg
     3541 gcaataatac caataaatac gttactgatc tgagcaaaag atggatcaac tgattctggt
     3601 ttgatattca ataaagtagc tactgaatca gtttttaaaa catttactgg aacttcaaat
     3661 gcgaccaaac ctgccaaggc agcagcacct gatttgtcca ctgacatccc tagtgctaac
     3721 ccaacggcaa acagcaaagg taattgacct aaaactgcgt taccgccagc ttgtaaaaaa
     3781 tgagcgacaa tgtcgttact ataagatgcc caccagtttc cgatccctac tagtaaagca
     3841 gcagcaggta agaccgcaac tggaagttga agggaacgtc ccattcgttg tagatatgct
     3901 ttcaattttt ttcctcctca tgattgttaa catttgtttg tacgattgcg cttcttaaac
     3961 gctcgatatg gatggccaag taacccagtt cttctttcgt gatcgcgagc tggtattctt
     4021 tggtcagcaa cacacggatt tttttagaaa tcttatagct ttctgggtat tttcgtttga
     4081 ccatttctac gatttccgtg tctaaaacag catattgttg cgcatgggtt cgttgtagaa
     4141 gtagtcgtaa atgattcacc agtcttgaat aattcagtga aaatggttct gaatggatat
     4201 ctgtttccaa ttctgattcc actaaatgga tgatgtcaga tacaatcgtc acttcacgga
     4261 tactgcgatg gttattgttc cgaccgcttc gtccgctgtg aatatggatt gcgatatatc
     4321 ctgcttcgtc ataagtatat ggaatcccaa gctcttttgt cagatactct actgcccatt
     4381 gagcaatact gaattcatca ctgtaaagca cttcgatttc tcttaaaagt ttgttgcgga
     4441 tgacgatacc gttattaatg ttctccgcag aaaaagcaat gtggtcggtc aaagcgatca
     4501 atacatgttc attcaacttt tccatcaaaa cagtttccgc atgatcaatg atcgtttctg
     4561 ctgcaaataa aaagcgttca tcaatctgat taagtaaatt ttgcaacttg atttgacctt
     4621 ctggttccat gacaaatatc cgttcgacat cacgatcaaa aatcaaatca tttctttttc
     4681 tgtcaaatcc aatccctttt ccaatagcta ctttttcctg tccaccgtca tctaccaata
     4741 ctgcattttg attaaagatc tttttgattt tcatgcgcgc accctttttg aagatttggt
     4801 tttcacgttt gctagaccag ttgattgcgg ccaaacaaaa atagacacga aaaacctcct
     4861 agggaaacca tgttcctcag agatttttca tgcctagtat gatctagtca catgaaacga
     4921 attattgtta acgtaatcaa ttttatatag acagttatgt tttgtcaatt ctttttttat
     4981 aattatagta atttactgga attatcagaa ataaaaggaa gaaataaatt aagaaactta
     5041 tgttatttaa tcgttggatc ttttgcttat cttattcgtt gttaaaaagc tgaaagcgaa
     5101 ggaaaaaaac tctacttaac tgtatttctc cgttaggaca tctaaaaatt tacgagcagc
     5161 aggagaaaga ggctggtctt ttttccaaat gagattcagt gaagcttgta atggcggatc
     5221 gagtgggatg aatatttttt ccgtcccata agtattgatg atcccatcta gagctaatgc
     5281 accaaaagtc ccgttatcga ccatcaaaga agcattgtac aataagttat atgttccgac
     5341 gatcgataac tgatctatgc tgaaacctag ccattcagct agttgactgt ccactgacgt
     5401 ttgccgggaa atgatcaaag gaacagtttt cagttcctgc ggatggatga cggtttgctt
     5461 tgctaaagga tgatttcgat gtatcaaaag tccccaacga tcttgggctg gcagtcgaaa
     5521 tgactggtat ttttgtttgt ttgtcggttc gattacgagt ccaaaatcaa gtaatccgct
     5581 atccagtttg tctatgatat catctgcatt cccgctatat aaatgaaact ggatatcagg
     5641 atgcgccttg atcaacgaat gaaggctatc agaaatgaaa gagattgctt tagtttcgcc
     5701 tccgccaatg tagatttctc cagagatgat tgcgtcattt gttaaattgt tcgccgtttt
     5761 ttctaccaac gacaagattt cttttccttt tgaataaaga tatcgaccag aatccgtcaa
     5821 ctgtatctct cgggagcccc gagtgaaaag tgtcacacca agttcttctt ctaaatcttt
     5881 cagttgtttt gagagagtag gttgcgtgat atgcagagat tttgctgctc ggctgatatt
     5941 tttttctcta gctactgcta aaaaatacgt cagtatacga atatccattt tttccctcct
     6001 gtttttaaaa aagcatacca ctaagtatag ttaaaaggaa tagttaagta tgttttataa
     6061 gtattagaca tgataagccg tccgttataa agtaaggata aaaggaggga gcaaaatgac
     6121 aagcctcatc gaaaaacaaa tcgtcaataa agagattcga gtaacggatc cgctctttga
     6181 agtgatccat cagatccaag ctgaaaacga agagccttta gcagcgctga atactgggta
     6241 ccatgaacca gcagatatcc gcaaacggct agaaaatatc attagtgaca aagtagatga
     6301 tacggtgact gttctgctgc ctttttatac agatttcggc aaacatatta gtatagggaa
     6361 aaatgtcttt atcaatcgtc aagtgatgtt cgttgactta ggtggcatct gtttagaaga
     6421 ttcagtattg attggtcctc gtgtcaacct catcacggtg aaccatctaa ccgatccaaa
     6481 agaacgaaga ggcttgtcag taaagccaat ccacatcaag aaaaatgctt ggatcggagc
     6541 aggagcaact attctgccag gcgtaacgat tggcgagaat gccattgttg cagcgaatgc
     6601 aactgttacg aaagatgtcc cagacaatac catcgttgca ggaatccctg ccaaaatcgt
     6661 caaacctgtc gaacggatta tttgaacagt aagatgaaat aagagatagt gagtataagc
     6721 aagagatttt tcaaaacagg aggagaatag aatgaatgat ttatcagaaa aagtgattgt
     6781 catcatgggc gcttcaagcg gaatcggtga agcaacaacg aagctattag cagaaaaagg
     6841 ggctaaacta gttatagctg cacgccgaga agatcgccta aaagcaataa aagaatcttt
     6901 accagaagct gagctatata ttcaaacagc agatgtaaga gattttgcac aagtccaagc
     6961 agttatcgat ttagcgatgg aaaagttcgg tcgaatcgat gtattgtaca ataatgcagg
     7021 aatcatgcca accgctccat tagttgaagg tcaccgtgat gaatggcaaa atatgcttga
     7081 tatcaacatc atgggtgtgt taaatggaat ttccgccgta cttccaatca tggaaaaaca
     7141 aaaatctggg catatcattt caactgattc tgtggcggga catgttgttt atcctgattc
     7201 cgccgtttat tgcggaacaa aatttgctgt ccgtgcaatc atggaaggat tacgtcaaga
     7261 gcaacggcaa aataacatca aatctacgat catctctcca ggagctgttc aaactgaatt
     7321 atatcaaacc atcagcgaca aaaaggctgc tcttgaactt catgaagcgc aaaaagaatg
     7381 gggattgacc tccgaagata tagcttctgc tgtagcattt gcgatagaaa cgccagaccg
     7441 gatgtctgtc agtaacatga ttatccgtcc gacgacacag gaagtataat ccataacgga
     7501 taatatccaa agagaattac ttgttaaata gttattcaaa cgaccatcaa tttaaggcgt
     7561 gaatggagaa gaatattctt catttacgtc tttttatgta gaaaaagcaa attcatcaaa
     7621 aagaaacaaa tgttatttaa atatggacat tgacttgctt ttactttttt agttacactg
     7681 ttatttagga aaagtttcat aattcaaagg agaaaaaaga tgaaagcaaa gaatttatta
     7741 tttagcgtta ttcttttagg aaatctagca gttgccaaca caacagtgct agctgaagaa
     7801 tcgacagaaa ctgtcgcaac tcagacatcg agttcttcag aaacaggaat tgaaaacgat
     7861 acagagagta ctttgcagtc agctactgtc tcagaaaata caatttcaac cgaagaacca
     7921 acaactgaaa caacagaaca aacacaaacc gaagacagta catcagcaga agctcagaac
     7981 aatccagaga atgcagaaga aatcacgaac caattgacag atgggcaaac attgacacat
     8041 acccatcaag cagatttgtc tgaattcgaa aactatactg gctatgcttt ttatgctcgc
     8101 tcatctgcta attctcaaca agcgttcatt gatagtattg cctcaactgc acaaagtttg
     8161 gcaagtgcca atgacttata tgcatcagtc atgattgctc aagccatcgt tgaaagtggc
     8221 tgggggaaca gtactttggc ttctgcccct aattacaatc tatttgggat taaaggaagc
     8281 tataatggcc aatctgttac gatgcctact tcggaatatg tgaatgggca atggattacg
     8341 gtgaatgccg cttttagaaa atatccttcg tacaaagaat cattgcaaga taacgtaacg
     8401 gtattgaaga cgacttcttt tcagccaggc gtttactact attccggtgc atggaaaagc
     8461 aatacgaact cttacaaaga tgctacggct tggctaacag gtcgttatgc cactgcgcct
     8521 aattatggtt ctacattgaa caatgtaatc gaaacctata atctgacaca gtatgataca
     8581 gcaccaactt caacttctcc gatgtatcgt ctgtataacc gtcatacagg agaacattta
     8641 tatacattga atgccggaga aaaaaattat ctgccaactg taggctggga atatgaaggg
     8701 attgcttggc aagcaccaaa cagcggacaa cctgtctacc gtttatacaa tccttacagt
     8761 ggagaccatc attacacaat ggcacaatct gagatcaact ctttaacaaa aatcggttgg
     8821 cgttatgaag gtctaagttt ttattctggt ggttccaagc caatttatcg actatttaat
     8881 ccaaatgaaa aaactggtac ccatcactat accttgagtg ctaaggaaag agattggcta
     8941 acaccgatgg gctggagata tgaaggaata ggattttatg gttattaaaa agaggtagtg
     9001 aaaaagctgc cctgcatcaa gtagtaagaa cagccaaaca aaaacagatt ttcatgtttt
     9061 ttgtttggtt gaacttatta ccgcagatgc aagtttttga acaccgttta ctcaaaaaag
     9121 gttgtgacaa catcttgtca taactttttt attactgttt aagcatactg atccaatttc
     9181 taatattcga cgggattctt gcaaaaggcg atttcggaaa tttttggcgg tgtaaaattt
     9241 tctactgcag aagagctatc ttctatagtt tgataagaat caataatctt ggttttagcg
     9301 ttgtgctttc tttatcattt tttccgttca ttctacaaaa aatttctttt ctctatactt
     9361 ttctattgag agcgtttttt ttattacaca gctgattctt tgactttttt ctttttttat
     9421 tctattattg acaagtcaat cgttgacgag tcaattatta gaaaggagga aattatgtct
     9481 ttagaagaga ttagtcacct tttatatcaa atcaaattag ccgatcaaaa aatcgtccag
     9541 atctttgaag aaaatatcgg tataagtctt actagatacg agatcatgat gagactgaaa
     9601 gaagaaaatc cattgctaca aagcagtttg caagaaaagt tgcagattga tcaaggagca
     9661 gttactcgtc atctgaaggt attggaagca aatggctatg tttcgcgtca gagaaatcct
     9721 cagaacaacc gggaagtgta tgtagcgcta acagaaaaag cccagaagaa aatcgagcat
     9781 tgtgaaatgg accataaaga tacaggttcc gtgctatccc cggctttcag cgatgtagaa
     9841 atgaaacaat ttctaacact tttagataaa ttgaataccc aactttgcaa tataacaaca
     9901 gaaacgaaag aggttaataa taatggaaca aaaaaatgat ttttcaacaa ttatgactgg
     9961 tagaagatcc gttcgcgtat atgatgaaac atacaaaatc ccacacgaag aaatgctgga
    10021 aatgatcaaa gaagcgacga ctgcaccttc ttctgtcaat atgcaaccat ggcgctttgt
    10081 ggtcgctgaa agcgaggaag caaaagaaat cttgcgtcct ttgatccgtt tcaatacgag
    10141 acaaaatgat acttcttctg caatggtcat gatttttggc gatatgcaat gttacgaata
    10201 tggcgaagaa atctataacc aagcttacga atcagggaag atgccaaaag aagtcagaga
    10261 tcaacaatta gctgcgatca ttccttatta caagagtttt tcaagagaag aaatgaacga
    10321 tgtagtcaaa gtcgattcta gcttagcggc tatgcaattc atgttagttg cgcgtgatca
    10381 tggctatgaa acaaatccaa ttggtggatt cgaagcagat cagttggcag aggcatttgg
    10441 tttggataaa gaccgttatg ttccagttat tattttatca ataggaaaag cggtagaaga
    10501 aggttacgag tctgttcgtt tagcaccaga aaagatcact acgttcgaat aaaaggtttt
    10561 cagttactat tcagtagcta ttgctttttt tgaatcgtgt gtggtaacct aataaaaaag
    10621 gaggtcggaa aaatgactgc atcgatgaaa ttacgtttcg aacttttgaa taacaactaa
    10681 ataaattcaa aagacatgta taaacaacaa tttcatggat ggagtatgtc cattttttcg
    10741 aacgacagta gaataggtga aagctatgac agatttggtg atttagtcat agttatttcg
    10801 ttcagagtag gaaaagatgt gatgcagttt ttttgcaaac agatttttct gctctttttt
    10861 agtatcgata attgttgttt tacatgaaat aggagtgtaa aacatatgga aaatttagca
    10921 gtaaatataa caaatctaca agtcagcttt ggcaaccagc tagaactatc tattgattct
    10981 cttcgtgtct atcagcaaga tcgtataggg atcataggag aaaatggtgt cggtaaatcg
    11041 actttgctca aactaatagc cggtgaactt tttcccgatc atgggaaaat ccaaacagag
    11101 atcaccttca actacctgcc tcaattaacc tatctcgctg aagcaaagga cctaaatttg
    11161 gaattagcca gtcatttcca gttaagactg gaagaaactt cagagcggaa atggagcgga
    11221 ggggaagaac gaaagatcga gttgatacgt cttctttctt cttatgaaca agggatgctt
    11281 ctagacgagc caacaaccca tctagataga aaaagtattg atcgactgat tgaagagctt
    11341 cgttattatt atggtacgct ggtttttgtt agtcatgatc gctattttct agatgagcta
    11401 gcatcgaaaa tctgggaagt aaaagacgga gaaatccgag agttttcggg gaattatagt
    11461 gcctatctca ctcaaaagga attggagaaa aagactcagc tacgagaagc agagtcgatc
    11521 atgaaagaga aaaaacgatt ggaaaaatcg atccaagaaa agaaaaaaca agcggaaaag
    11581 ttggaaaaag tgtccagtaa aaagaaaaag caacaaatca gaccggatcg gttgtcttcc
    11641 tctaaacaaa aagacagtgt acaaaaagcc atccaaaaga atgcgaaaac attagagaga
    11701 agactccaaa aaataggaga aacaaccaag ccgcagcaga tgaaacaaat ccgttttcca
    11761 gtaccaaaat ctcttgaact ccacagccgc tatcccatca tgggacaaaa tgtccaattg
    11821 gaaagaagtg ggagaacatt actggtaaat ggtgattttc agttttcttt aggtaaaaaa
    11881 atcgcgattg tcggtgaaaa tggttcaggt aagacaacct tattagaaca tatccgcaaa
    11941 caaggagaag gaatccttct ctctccgaaa gtaagctttc aagtatatca gcaaaagggt
    12001 tatcaaatga catctgaaga atccatcatt cgttttgtca tgagacaaac agagttttca
    12061 gaatcgcttg tccgtagttt gctgaatcac ttagggtttg ctcaggaaac tttgacgaaa
    12121 ccgttatgta cattaagtgg gggagaagcg acccgtctga cgattgcttt gctttttact
    12181 aagccaagta atgtgttgct gttagatgaa ccgactaatt ttattgatat ggcaacgatc
    12241 gaagctttag agaagctaat gcaaatatat ccgggaacga ttttgtttac ttctcatgat
    12301 tcttactttg tcgagcgtac ggctgatgaa gtttatgaaa taaaagggca gaaaataaaa
    12361 aaagtactta cgagaaattt ttaaatgtgc tacgatgatt ttcgtgacaa atttaaagga
    12421 gtggtacaga ttgcctacaa ataaaaaaga aggaataatt tttacaacaa tgatgtgttt
    12481 tttgatggtc ttggggatga gcgcgtataa tttatggctg catcaagatc ttcatttatc
    12541 aagtttgttg attggtctag tgcctggatt cgtggtggct ttcattttgg atgtcttcat
    12601 catcggtgtg ctggcgaaaa aaattgcctt taaactacca gtaaatccag aaagcaaggt
    12661 ccaaatgatc ttaactattt catgcttgat ggttttagga atggtgacat gtatgtcttt
    12721 attcggtgtg atcatggaac aaggaatacc tgatcaatta ttctctgctt atatgaatgc
    12781 ttggaaaatg aatgtgattg ccgctttacc gttgcagttg atcatcgttg gcccgctttc
    12841 aagaagtgtg ctaaaagcaa ttcaaagtaa tgaatgatgg aacactgtta tttgaaaaaa
    12901 ggccttggca tgctttttgt catagtctct tgaatgcagt tctagaaaaa tagtgatccg
    12961 aacgataggt tttggcctgt cgttcggatc gctttttctt ttccaactgt attgctcttt
    13021 tattgaagat aatttgctct tcaatagata tttctagaaa ggttctgttt atcccttact
    13081 caaaaaactg ctgcatttgt tctcttactt gctgacacca ttggagttcc tgctgacaaa
    13141 gcataattct gcgctggatc acaacataac gtccaaattc ttgtttcttg tctagcgaga
    13201 ggtcattcaa ttttttttga tttttttgca tgattttgtt cagctgttgt tctctagtga
    13261 atagcagtcc agtagctgtt gttttatcga gcgtcgaaaa agcatagatt tttgctagaa
    13321 attcatcttt ttgcgtagga gcgggagttt cctctttgat ccattcctct acaagagcac
    13381 gtccttcatc agtcaagtgg tagatctttt tttgagagtg ctcgtctttg tccaaaacgg
    13441 tcacataacc ctgctggtct aacttggcaa gcgttgtata gatctgactg tgatgggctt
    13501 cccaaaaaat tgtgatcagc tgcttcaatt catacccaga acgtggtttg gataaaagca
    13561 cgcataataa tatataggct aaagtattca taaaaatcct acctctcgtc ttattttctt
    13621 tattatatca cagtaaagtt tccacgtttt acatgtgcat atttacatgt aaaataaatc
    13681 atgtatgatg ctaatagaga gaaagggatg gaaatattgg agaatcaaat agatatacaa
    13741 gaacaaacaa atgaagaaac aaaggggaaa agttcagcgc tagttgtagc agctacctgt
    13801 atgatcgctt ttatgggagt gggtctagta gacccaatct taaaaacgat tgctgcacag
    13861 ttaaacgcta cgccagctga aacgaccctg ttatttacta gttacatgtt agtcactggt
    13921 gtggtgatgc tatttacagg tttcttatct agtcggatcg gtttgaaaaa aacattgatg
    13981 acaggattgt ttatcatcgt tgtattcgct ggtcttggcg gattatctgg gaatatcgga
    14041 atgctgattg ggttacgtgc cggctggggt gtcgggaatg ctttatttgt ctctactgct
    14101 ttagcaacga tcgtcagtat tttagttggt aacacagaaa aagcaatcat gatgtatgaa
    14161 gcagcacttg gctgcggaat ggctgttggc cctctagtcg gtggggtctt gggcagtggt
    14221 tcatggcgtt atccattttt tggggtagca tttttgatgt tttgcggttt tatagcccta
    14281 gcggtacttt tacctgaaac tgagaaacca aagagaaaag taggcctttg ggaaggtgtc
    14341 aaagcgttaa gcaatcataa acttcgttca gttggactaa tcgcattgtt atataatttc
    14401 ggattcttta ctttacttgc gtatgcgcca tttttattga ttggctattc tgaattagaa
    14461 gtcggttttg tattttttgg ctggggtgtg cttctggcta ttgcttcgat tttcgttgca
    14521 ccggctcttg agcggaagtt tacgacttat cggacaattt tagcagcatt tgtcttattc
    14581 attatttgtt tgctgttatt aggagctgga acttctatgc cagtccttgt accgatcagc
    14641 attgtgttag caggattttt ccaaggaatt atcaatacac tgttgacgac gattgctatg
    14701 gaaataccag gtctgcaacg aaacgttgct tcgtccagct atagttttgt ccgctttttc
    14761 ggtggagctt tagcaccatt tattgcaggt gtgattggtg aacatattgg tgaaagctat
    14821 gcgttttatt ttgcaggtgc cattgttctt atcagtgtat gttgtatcat ttatcaccgt
    14881 aattattttg ctacaaatga agaagaataa gaaatcagag gttgtgaaaa agctgtcctg
    14941 catcaagtca taagaa
//
LOCUS       DAFEIE010000197         8061 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.guided.093, whole genome shotgun sequence.
ACCESSION   DAFEIE010000197
VERSION     DAFEIE010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.guided.093"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            128..1564
                     /locus_tag="LP345_002965"
     CDS             128..1564
                     /locus_tag="LP345_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1761670.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="LP345_002966"
     CDS             1753..4200
                     /locus_tag="LP345_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL1761671.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="LP345_002967"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="LP345_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL1761672.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="LP345_002968"
     CDS             complement(5690..6793)
                     /locus_tag="LP345_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1761673.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="LP345_002969"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="LP345_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL1761674.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2695 a         1375 c         1751 g         2240 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattacttc ttgaattttt gtgaaattcc
     7981 aacttatttc cgaagaagct acttttggaa caccgtgtac cagaggttgt gaaaaagtcg
     8041 cttagtttcg agtagtaaga a
//
LOCUS       DAFEIE010000198         7768 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.guided.094, whole genome shotgun sequence.
ACCESSION   DAFEIE010000198
VERSION     DAFEIE010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.guided.094"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            234..1202
                     /locus_tag="LP345_002970"
     CDS             234..1202
                     /locus_tag="LP345_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL1761675.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1195..2226
                     /gene="vanA"
                     /locus_tag="LP345_002971"
     CDS             1195..2226
                     /gene="vanA"
                     /locus_tag="LP345_002971"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL1761676.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2232..2840
                     /locus_tag="LP345_002972"
     CDS             2232..2840
                     /locus_tag="LP345_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL1761677.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3246..4178
                     /gene="vanY"
                     /locus_tag="LP345_002973"
     CDS             3246..4178
                     /gene="vanY"
                     /locus_tag="LP345_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBL1761678.1"
                     /translation="MVKEETENEEVVFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYD
                     QNPKEHLENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDEL
                     INGYGLLDSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAE
                     YALPAGYSEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQ
                     YEPWHIRYVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTT
                     IHVPTNLRYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4331..4816
                     /gene="vanZ"
                     /locus_tag="LP345_002974"
     CDS             4331..4816
                     /gene="vanZ"
                     /locus_tag="LP345_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL1761679.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5103..5432)
                     /locus_tag="LP345_002975"
     CDS             complement(5103..5432)
                     /locus_tag="LP345_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1761680.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5737..6066
                     /locus_tag="LP345_002976"
     CDS             5737..6066
                     /locus_tag="LP345_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1761681.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6056..6343
                     /locus_tag="LP345_002977"
     CDS             6056..6343
                     /locus_tag="LP345_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1761682.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6622..7185)
                     /locus_tag="LP345_002978"
     CDS             complement(6622..7185)
                     /locus_tag="LP345_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1761683.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         2564 a         1294 c         1545 g         2365 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca taatttttta ggaaaatctc
       61 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctggtag
      121 acttaatacc gtaagaacga gccgttttcg ttcttcagag aaagatttga caagattacc
      181 attggcatcc ccgttttatt tggtgccttt cacagaaagg gttggtctta attatgaata
      241 acatcggcat tactgtttat ggatgtgagc aggatgaggc agatgcattc catgctcttt
      301 cgcctcgctt tggcgttatg gcaacgataa ttaacgccaa cgtgtcggaa tccaacgcca
      361 aatccgcgcc tttcaatcaa tgtatcagtg tgggacataa atcagagatt tccgcctcta
      421 ttcttcttgc gctgaagaga gccggtgtga aatatatttc tacccgaagc atcggctgca
      481 atcatataga tacaactgct gctaagagaa tgggcatcac tgtcgacaat gtggcgtact
      541 cgccggatag cgttgccgat tatactatga tgctaattct tatggcagta cgcaacgtaa
      601 aatcgattgt gcgctctgtg gaaaaacatg atttcaggtt ggacagcgac cgtggcaagg
      661 tactcagcga catgacagtt ggtgtggtgg gaacgggcca gataggcaaa gcggttattg
      721 agcggctgcg aggatttgga tgtaaagtgt tggcttatag tcgcagccga agtatagagg
      781 taaactatgt accgtttgat gagttgctgc aaaatagcga tatcgttacg cttcatgtgc
      841 cgctcaatac ggatacgcac tatattatca gccacgaaca aatacagaga atgaagcaag
      901 gagcatttct tatcaatact gggcgcggtc cacttgtaga tacctatgag ttggttaaag
      961 cattagaaaa cgggaaactg ggcggtgccg cattggatgt attggaagga gaggaagagt
     1021 ttttctactc tgattgcacc caaaaaccaa ttgataatca atttttactt aaacttcaaa
     1081 gaatgcctaa cgtgataatc acaccgcata cggcctatta taccgagcaa gcgttgcgtg
     1141 ataccgttga aaaaaccatt aaaaactgtt tggattttga aaggagacag gagcatgaat
     1201 agaataaaag ttgcaatact gtttgggggt tgctcagagg agcatgacgt atcggtaaaa
     1261 tctgcaatag agatagccgc taacattaat aaagaaaaat acgagccgtt atacattgga
     1321 attacgaaat ctggtgtatg gaaaatgtgc gaaaaacctt gcgcggaatg ggaaaacgac
     1381 aattgctatt cagctgtact ctcgccggat aaaaaaatgc acggattact tgttaaaaag
     1441 aaccatgaat atgaaatcaa ccatgttgat gtagcatttt cagctttgca tggcaagtca
     1501 ggtgaagatg gatccataca aggtctgttt gaattgtccg gtatcccttt tgtaggctgc
     1561 gatattcaaa gctcagcaat ttgtatggac aaatcgttga catacatcgt tgcgaaaaat
     1621 gctgggatag ctactcccgc cttttgggtt attaataaag atgataggcc ggtggcagct
     1681 acgtttacct atcctgtttt tgttaagccg gcgcgttcag gctcatcctt cggtgtgaaa
     1741 aaagtcaata gcgcggacga attggactac gcaattgaat cggcaagaca atatgacagc
     1801 aaaatcttaa ttgagcaggc tgtttcgggc tgtgaggtcg gttgtgcggt attgggaaac
     1861 agtgccgcgt tagctgttgg cgaggtggac caaatcaggc tgcagtacgg aatctttcgt
     1921 attcatcagg aagtcgagcc ggaaaaaggc tctgaaaacg cagttataac cgttcccgca
     1981 gacctttcag cagaggagcg aggacggata caggaaacgg caaaaaaaat atataaagcg
     2041 ctcggctgta gaggtctagc ccgtgtggat atgtttttac aagataacgg ccgcattgta
     2101 ctgaacgaag tcaatactct gcccggtttc acgtcataca gtcgttatcc ccgtatgatg
     2161 gccgctgcag gtattgcact tcccgaactg attgaccgct tgatcgtatt agcgttaaag
     2221 gggtgataag catggaaata ggatttactt ttttagatga aatagtacac ggtgttcgtt
     2281 gggacgctaa atatgccact tgggataatt tcaccggaaa accggttgac ggttatgaag
     2341 taaatcgcat tgtagggaca tacgagttgg ctgaatcgct tttgaaggca aaagaactgg
     2401 ctgctaccca agggtacgga ttgcttctat gggacggtta ccgtcctaat cgtgctgtaa
     2461 actgttttat gcaatgggct gcacagccgg aaaataacct gacaaaggaa agttattatc
     2521 ccaatattga ccgaactgag atgatttcaa aaggatacgt ggcttcaaaa tcaagccata
     2581 gccgcggcag tgccattgat cttacgcttt atcgattaga cacgggtgag cttgtaccaa
     2641 tggggagccg atttgatttt atggatgaac gctctcatca tgcggcaaat ggaatatcat
     2701 gcaatgaagc gcaaaatcgc agacgtttgc gctccatcat ggaaaacagt gggtttgaag
     2761 catatagcct cgaatggtgg cactatgtat taagagacga accatacccc aatagctatt
     2821 ttgatttccc cgttaaataa acttttaacc gttgcacgga caaactatat aagctaactc
     2881 tttcggcagg aaacccgacg tatgtaactg gttcttaggg aatttatata tagtagatag
     2941 tattgaagat gtaaggcaga gcgatattgc ggtcattatc tgcgtgcgct gcggcaagat
     3001 agcctgataa taagactgat cgcatagagg ggtggtattt cacaccgccc attgtcaaca
     3061 ggcagttcag cctcgttaaa ttcagcatgg gtatcactta tgaaaattca tctacattgg
     3121 tgataatagt aaatccagta gggcgaaata attgactgta atttacgggg caaaacggca
     3181 caatctcaaa cgagattgtg ccgtttaagg ggaagattct agaaatattt catacttcca
     3241 actatatagt taaggaggag actgaaaatg aagaagttgt ttttttattg ttattgttat
     3301 tcttaatata cttaggttat gactacgtta atgaagcact gttttctcag gaaaaagtcg
     3361 aatttcaaaa ttatgatcaa aatcccaaag aacatttaga aaatagtggg acttctgaaa
     3421 atacccaaga gaaaacaatt acagaagaac aggtttatca aggaaatctg ctattaatca
     3481 atagtaaata tcctgttcgc caagaaagtg tgaagtcaga tatcgtgaat ttatctaaac
     3541 atgacgaatt aataaatgga tacgggttgc ttgatagtaa tatttatatg tcaaaagaaa
     3601 tagcacaaaa attttcagag atggtcaatg atgctgtaaa gggtggcgtt agtcatttta
     3661 ttattaatag tggctatcga gactttgatg agcaaagtgt gctttaccaa gaaatggggg
     3721 ctgagtatgc cttaccagca ggttatagtg agcataattc aggtttatca ctagatgtag
     3781 gatcaagctt gacgaaaatg gaacgagccc ctgaaggaaa gtggatagaa gaaaatgctt
     3841 ggaaatacgg gttcatttta cgttatccag aggacaaaac agagttaaca ggaattcaat
     3901 atgaaccatg gcatattcgc tatgttggtt taccacatag tgcgattatg aaagaaaaga
     3961 atttcgttct cgaggaatat atggattacc taaaagaaga aaaaaccatt tctgttagtg
     4021 taaatgggga aaaatatgag atcttttatt atcctgttac taaaaatacc accattcatg
     4081 tgccgactaa tcttcgttat gagatatcag gaaacaatat agacggtgta attgtgacag
     4141 tgtttcccgg atcaacacat actaattcaa ggaggtaagg atggcggaat gaaaccaacg
     4201 aaattaatga acagcattat tgtactagca cttttggggt aacgttagct ttttaattta
     4261 aaacccacgt taactaggac attgctatac taatgataca acttaaacaa aagaattaga
     4321 ggaaattata ttgggaaaaa tattatctag aggattgcta gctttatatt tagtgacact
     4381 aatctggtta gtgttattca aattacaata caatatttta tcagtattta attatcatca
     4441 aagaagtctt aacttgactc catttactgc tactgggaat ttcagagaga tgatagataa
     4501 tgttataatc tttattccat ttggcttgct tttgaatgtc aattttaaag aaatcggatt
     4561 tttacctaag tttgcttttg tactggtttt aagtcttact tttgaaataa ttcaatttat
     4621 cttcgctatt ggagcgacag acataacaga tgtaattaca aatactgttg gaggctttct
     4681 tggactgaaa ttatatggtt taagcaataa gcatatgaat caaaaaaaat tagacagagt
     4741 tattattttt gtaggtatac ttttgctcgt attattgctc gtttaccgta cccatttaag
     4801 aataaattac gtgtaagatg tctaaatcaa gcaatctgat ctttcataca cataaagata
     4861 ttgaatgaat tggattagat ggaaaacggg atgtggggaa actcgcccgt aggtgtgaag
     4921 tgaggggaaa accggtgata aagtaaaaag cttacctaac actatagtaa caaagaaagc
     4981 ccaattatca attttagtgc tgaggaattg gtctctttaa taaatttcct taacgttgta
     5041 aatccgcatt ttcctgacgg tacccccaaa ctaagatttc atagatagat tttctgataa
     5101 ctttaaaaaa cacgaatagc ggaaaggatg tcttcattcg ctaaagagta ataaactact
     5161 tttccatctt gacgtgattt tgccattcca tgttttttta aaaaacgtaa atggtgtgac
     5221 gttgtagcga cactagcagt aagtatttct gctaaatcac agacgcacat ttccttatag
     5281 gtttctaaag catagaaaat tttaattcta gaaaaatcgc tgaaacattt ccctaacaca
     5341 agtaagtttg aaaaatcttt ttgatccaat ttatttttta ttccatttac tttttcttta
     5401 tgtacgacag tcacttggca aacttttttc attcatctca cctcacattc aaacgattat
     5461 ttgaatgaag tatacctatt tgatcactct tttgtcaatc taccttaatt ccaatacact
     5521 attataagca atttcatgta ttgaagtaaa cttacttgca agtgcgtttt tgattccaag
     5581 ttaaaaacat attattattc tacataattt cctaatcaaa taaaactcct ttgaaaattg
     5641 ttctaaagga gttttattat tttgtatttc tactaaaaat agcgtacaat gtaattacta
     5701 agtaattacg aaatgtaaaa taatggagga aataatatga ttacaaaaac aagaaaacaa
     5761 ggaaattcta ttatgttaac ggtccctaaa gaattcgatg tgcccaatgg tgttgaagta
     5821 gaagctaagc ttgtagagaa tggtatcctt tatgagtttg tagagcctaa aaaagaattt
     5881 tttgatttta gtgaagatat tttggctgat attctttcag aaggttatag caaacaagag
     5941 atcttaaaag aatttagaaa tagaaaaaat gcgttaactt ctgcatttaa atctattgct
     6001 gaagatactg ttgcaaattc taaaccgatg acaaaagagg agttggcagc agaaattggc
     6061 ttatgagatt ctaccttcta aacacgtaat aaagtatcta aaaaaattaa aagagaaaac
     6121 attaaaagaa caatttttaa cgataattta tgatgagata gcagttcgtc ctcattcggg
     6181 agaacaaaaa acgggtgatt tatcaggaat ttgggctatt ggattcaagt atgcaggtac
     6241 gacatatcgc gttgcatatg aaattaaaga taatgcagtg atacctatct tactatgtgg
     6301 aacgcatgaa aatttttatg aacaattaaa aaagattagg taagaaccca atgtttcaac
     6361 ttgagaggat agacgacact ttaaaagata atttttaaca gctgagagtt gtaataccct
     6421 ataattttaa accactaacc tatatattta tgaaaaatag aaaaaattaa aacgcatttt
     6481 aagcctcttt caaattaaaa gcttcatcct tatgcacaaa gagggcttaa aatgcgttat
     6541 tttatattgt tttttagtaa taataaaaaa atcactctaa ttctcccata aatattatag
     6601 attcctaaag attaaaatag attattccct attgtctttt aagtagcggt agagtgttgc
     6661 cttgctaata ccagtcattt ccgtaatttc ttttacgcta taaacctgac ttttatacaa
     6721 ttttactgct cgatcaacat ctttctggtt cactcgtgga cggccacctt tacgacctct
     6781 cgcacgtgca cttttcaaac cttctttggt acgttcaaca attaaatcac gttcgaactg
     6841 actaaatgct tggaagacag tcatcattaa gcgtccgtga ggcgtgctgg tatcgaagtt
     6901 ttctttcaag ctcaccagct taacatggtg ttcttcaaaa taggtaacaa ggtcaatcaa
     6961 atcctttgta ctacgaccca atcgagaaaa actttctaca attaccgtat ctcccggacg
     7021 aattttatct tttaaacgat ttagttgggg acgaaccgct ttggttcccg tcattttctc
     7081 agttaggatt tcattacaat tttgttcatt gagtaagtct aattgacgat ttagttcttg
     7141 tgaacgtgta ctcactcggg cataaccata aatgtatcca ctcatgcttt tcttcctttc
     7201 gtactttaat tctggcttga ttgtatcata aaagggagtt atagatacat agttaatgca
     7261 acaagttatg atacaaaata tgacctcttt tatttaataa aagaggtcat ttcattttgt
     7321 ctcataatcg attgtttttg atacgagtgt gtatacgaaa taaacaaaaa aatcttaagt
     7381 aaatttctag atacctaatt taatcctaac tagtgtatcc taaagttaat aacgagttta
     7441 tcacaatgaa aattataaaa tgctcccata ttagatataa catgcaatat ttgaattaga
     7501 actacaaaat ttattcgttt tataaagtaa ataatgttga gatactaagg aatagaatat
     7561 tataaggaat tgagctgaat gtattggata aaaaaagaat aactttatta gagatggact
     7621 ataaaaatgc tcgtaatttt cttctgaagt ctgaaagcta tttgaatgct cagctaccag
     7681 aatatattag ttttgacgaa actttaaaat ctgctaaaaa agttttaact tcgccgtttg
     7741 tataattaag cgagacaaat aaaaaagc
//
LOCUS       DAFEIE010000199         6752 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.guided.099, whole genome shotgun sequence.
ACCESSION   DAFEIE010000199
VERSION     DAFEIE010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.guided.099"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            111..194
                     /locus_tag="LP345_002979"
     CDS             111..194
                     /locus_tag="LP345_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBL1761684.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="LP345_002980"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="LP345_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL1761685.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1226..1486
                     /locus_tag="LP345_002981"
                     /pseudo
     CDS             1226..1486
                     /locus_tag="LP345_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1649..2314
                     /locus_tag="LP345_002982"
                     /pseudo
     CDS             1649..2314
                     /locus_tag="LP345_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2350..2595
                     /locus_tag="LP345_002983"
     CDS             2350..2595
                     /locus_tag="LP345_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1761686.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2698..3567
                     /locus_tag="LP345_002984"
     CDS             2698..3567
                     /locus_tag="LP345_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL1761687.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3548..4282
                     /locus_tag="LP345_002985"
     CDS             3548..4282
                     /locus_tag="LP345_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1761688.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4315..5230
                     /gene="ant(6)"
                     /locus_tag="LP345_002986"
                     /pseudo
     CDS             4315..5230
                     /gene="ant(6)"
                     /locus_tag="LP345_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5227..5769
                     /gene="sat4"
                     /locus_tag="LP345_002987"
     CDS             5227..5769
                     /gene="sat4"
                     /locus_tag="LP345_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBL1761689.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5862..6656
                     /locus_tag="LP345_002988"
                     /note="aph(3')-IIIa"
     CDS             5862..6656
                     /locus_tag="LP345_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL1761690.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2366 a         1016 c         1407 g         1963 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 aacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 attcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac tactgacagc
     1141 ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat aaggggtaca
     1201 aattcccact aagcgctcgg gaccccttgt aggaaaatgt cctaagtgtg gcaacaatat
     1261 tgtattaaaa aaatcgtttt atggttgttc aaattatcct gaatgtaagt ttactttagc
     1321 tgaacatttt agaaagaaaa aactaaccaa aacgaatgta aaagaattac tggagggaaa
     1381 agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag ccctacaatg ccgttgtaaa
     1441 aattggggaa aagggatata ttgattttat ctctttttca aaataaacat ggggctgacc
     1501 caaaagtagc tcctatatga aaaatagagg tctttccatt tagatagtag tggaaagacc
     1561 tctatttatc ttttgaaagt gaatacaaaa ataaagcaca ctctgctata atataggtga
     1621 ttaatccatt tgagagaggt gctttatcat gtatcaaaat tataccataa accaactttg
     1681 tttgcctata gatcttgaaa ttaaattaga agaaaatgat tttgctcatg ccattgtgca
     1741 gtttgttgac tctattcccg atgaagtctt tcttccttat tatcaatcta tgggtagacc
     1801 ccaatatcat cctcgtatgc tactttccat tattctttgt gcctatattc aaggggttta
     1861 ttcgggccgc caaatacaaa atatgctgat agatagtatt cggatgcgct acttatctca
     1921 agagcaattc cctaactttc gtactattaa tcgttttcgc gttcatccga ttatgaacga
     1981 tattctagat cattcatttg ttcaatttcg tgagctactg gttcaaagtg gcttaatcag
     2041 tggcagtgct ctatacattg atggtacaaa aattgaagcg gatgcgaata aatactcttt
     2101 cgtttggaaa aaaagtattt taaagtataa ggatagcctt gatcaaaaag cccttgaaaa
     2161 ctaccaacaa atggtggaaa caaaaatctt acctgagtta atagatgatt taaaggatga
     2221 actttctata gaagagattg aaaggattcg tcaatctttg gaagaaaagg aaaatcaatt
     2281 aattgaagcg attgaccaaa ccgaaacagt agaagggggc tgacccatta ttaataagga
     2341 gtggacaaca tgattgatgt aaatgagcta ttggaagaag ctattagaga aactgaaaat
     2401 ctaaatgatg gcgaagtttt tcttgttaaa gatttattca agggatatgt ggggaatagg
     2461 atacccagaa aggatcgact tctgcttgga acgttatttt taaaccatgt tagcaaaatg
     2521 aatggtaatt taaaggctat tgaaaagact tcatctaatc agcagaggta taaaaagaca
     2581 attgataagt tttaactatc ttttgtgaaa ttaaaaaaat tataaatatg ttgagtagaa
     2641 gcaaaagatt tggcttggaa tttttacagc agtgaatcga taaaaggagc atgcttgatg
     2701 gtagataata ttattaaatc agtagcagag aaattatcct ctctgtctta tatagaaggt
     2761 attgttttag gtggttcacg tgcaaggggc acccatacag aggattcgga tatagatatc
     2821 ggcatctatt acaattcaga atcatttgac ataaatacta ttaatcaatt cgctacaaag
     2881 ctggatgatg agcatagaaa taaccttgtt gtacctcccg gagcatgggg tgattggatt
     2941 aatggcggcg gatggttagt cataaacggg tatcatgtgg atttaatttt acgtgatatt
     3001 aaacgtgtgg aacaaataat gaaagataca gagcacggaa ttgttactgc caattatcag
     3061 actgggcatc cccatggtta tattagtgca atgtatcgag gagaattagc gattagcaaa
     3121 atactatatg ctaagaatga aagcttatgc gaattaaaaa aacaggcaga aacttatccc
     3181 aatgctttgc agaaaagttt agttaacttt tttatgtttg aagcagggtt ctctttaatg
     3241 tttgtaaaag caaattcggg aacagacgat aaatattata ttgcgggtca tgtttttcgt
     3301 atagtttcat gtttaaatca agtgttattt gcatgtaata atgcttattg tatcaacgaa
     3361 aagaaagcta taaaactgct tgaaactttt gaacataaac ctgaaaaata taccgagaag
     3421 gtaaatcata tttttgaagt actcggtatc tcactttttg aatgctacga catgaccgag
     3481 aagctttata atgaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag
     3541 agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat
     3601 gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct
     3661 acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat
     3721 atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct
     3781 cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga
     3841 agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta
     3901 tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa
     3961 tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta
     4021 taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg
     4081 gacagctatg tttttggaag aaaaggttac aaaatatcat agaacactga ccacatatct
     4141 aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac agccgccaga
     4201 gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga tgctgattgt
     4261 atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat gtaaatgaga
     4321 tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga acgtattcga
     4381 attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga atttcaggat
     4441 tatgatatta catattttgt aagtgatata gaacctagaa ccgtttatat ctaatgatga
     4501 ctggcttaat caatttggga atataataat gatgcaaaag ccggaggata tggaattatt
     4561 cccacctgaa gaaaagggat tttcctatct tatgctattt gatgattaca ataaaattga
     4621 tcttacctta ttgcccttgg aagagttaga taattaccta aagggcgata aattaataaa
     4681 ggttctaatt gataaagatt gtagaattaa aagggacata gttccgactg atatagatta
     4741 tcatgtaaga aagccaagcg caagggagta tgatgattgc tgcaatgaat tttggaatgt
     4801 aacaccttat gttattaaag gattgtgccg taaggaaatt ttatttgcta ttgatcattt
     4861 taatcagatt gttcgccatg agctgctgag aatgatatca tggaaggtcg gcatcgaaac
     4921 aggctttaaa ttaagtgtag gcaagaacta taagtttatt gaaaggtata tatccgagga
     4981 tttgtgggag aaacttttgt ccacctaccg gatggattcc tatgaaaaca tatgggaagc
     5041 attatttcta tgccatcaat tgttcagggc ggtatccggt gaggtggcgg aaaggcttca
     5101 ttatgcctat ccggagtatg ataggaatat aacaaaatat accagggaca tgtataaaaa
     5161 atacactggt aaaaccggct gcctggatag cacatatgcc gctgatatag aagagaggcg
     5221 ggaacagtga ttacagaaat gaaagcaggg cacctgaaag atatcgataa acccagcgaa
     5281 ccatttgagg tgataggtaa gattataccg aggtatgaaa acgagaattg gacctttaca
     5341 gaattactct atgaagcgcc atatttaaaa agctaccaag acgaagagga tgaagaggat
     5401 gaggaggcag attgccttga atatattgac aatactgata agataatata tctttactac
     5461 caagacgata aatgcgtcgg aaaagttaaa ctgcgaaaaa attggaaccg gtacgcttat
     5521 atagaagata tcgccgtatg taaggatttc agggggcaag gcataggcag cgcgcttatc
     5581 aatatatcta tagaatgggc aaagcataaa aacttgcatg gactaatgct tgaaacccag
     5641 gacaataacc ttatagcttg taaattctat cataattgtg gtttcaaaat cggctccgtc
     5701 gatactatgt tatacgccaa ctttgaaaac aactttgaaa aagctgtttt ctggtattta
     5761 aggttttaga atgcaaggaa cagtgaattg gagttcgtct tgttataatt agcttcttgg
     5821 ggtatcttta aatactgtag aaaagaggaa ggaaataata aatggctaaa atgagaatat
     5881 caccggaatt gaaaaaactg atcgaaaaat accgctgcgt aaaagatacg gaaggaatgt
     5941 ctcctgctaa ggtatataag ctggtgggag aaaatgaaaa cctatattta aaaatgacgg
     6001 acagccggta taaagggacc acctatgatg tggaacggga aaaggacatg atgctatggc
     6061 tggaaggaaa gctgcctgtt ccaaaggtcc tgcactttga acggcatgat ggctggagca
     6121 atctgctcat gagtgaggcc gatggcgtcc tttgctcgga agagtatgaa gatgaacaaa
     6181 gccctgaaaa gattatcgag ctgtatgcgg agtgcatcag gctctttcac tccatcgaca
     6241 tatcggattg tccctatacg aatagcttag acagccgatt agccgaattg gattacttac
     6301 tgaataacga tctggccgat gtggattgcg aaaactggga agaagacact ccatttaaag
     6361 atccgcgcga gctgtatgat tttttaaaga cggaaaagcc cgaagaggaa cttgtctttt
     6421 cccacggcga cctgggagac agcaacatct ttgtgaaaga tggcaaagta agtggcttta
     6481 ttgatcttgg gagaagcggc agggcggaca agtggtatga cattgccttc tgcgtccggt
     6541 cgatcaggga ggatatcggg gaagaacagt atgtcgagct attttttgac ttactgggga
     6601 tcaagcctga ttgggagaaa ataaaatatt atattttact ggatgaattg ttttagtacc
     6661 tagatttaga tgtctaaaaa gctttaacta caagcttttt agacatctaa tcttttctgg
     6721 ctctttgtca aatgatgttg gtaaagagaa at
//
LOCUS       DAFEIE010000200         4544 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.guided.119, whole genome shotgun sequence.
ACCESSION   DAFEIE010000200
VERSION     DAFEIE010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.guided.119"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            348..1562
                     /locus_tag="LP345_002989"
     CDS             348..1562
                     /locus_tag="LP345_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBL1761691.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1593..1811
                     /locus_tag="LP345_002990"
                     /pseudo
     CDS             1593..1811
                     /locus_tag="LP345_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2230..2703
                     /gene="dfrF"
                     /locus_tag="LP345_002991"
     CDS             2230..2703
                     /gene="dfrF"
                     /locus_tag="LP345_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL1761692.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            2830..3486
                     /locus_tag="LP345_002992"
     CDS             2830..3486
                     /locus_tag="LP345_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBL1761693.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            3668..4198
                     /locus_tag="LP345_002993"
     CDS             3668..4198
                     /locus_tag="LP345_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1761694.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT         1520 a          667 c          960 g         1397 t
ORIGIN      
        1 atagaatgat tttctatcag tcctagaaat tatagagccg aacaaatttg agaaccgtag
       61 cgacactcgc tgcggttctt ttttatatat tttatatgaa gtattcttta ttccttatga
      121 aaaaatatct ttaaaaataa aaaaagacga aaataaacgg ttttctataa aaagaagacc
      181 gtttattttt tgtctttatt tgtgtgaaaa acgaaaaaga gcacaacaca tcaagctttt
      241 attaattgtc tgtcttttat aaatgcaagt attaattcaa aaaaacagaa gaaaaaaaca
      301 actacacctt cttttatact cgtaatcgta gaaaggaggc gaaaaaaatg aatacattac
      361 ctatcaatac aggagataca gcattcatga ttttatgtac agcaatggtt tgcctgatga
      421 ctcctggtct agcttttttt tacggcggat tagcacggaa gaataatata ctaacgatca
      481 tgtctcaatc ttttctctcc gttgggataa caacgattat gtgggtattt ggtggattcg
      541 gattggcctt tggacgggat atcggcggtg ttattggaaa cccggcagat ttctttttga
      601 tgagacatgt tacaagcttc cccaacatgt ttcatggtgc aacgattcca tttttaatgt
      661 tctttcttta ccaactgatg tttatcgtga ttaccgttcc tttgatgaca ggagcttttg
      721 cagggagatt gaatttaaaa ggctatatta tacttgttat tttttggaat ctgctgattt
      781 atttccctgt ttgccactgg atatggggtg gcggattttt ggatcagatg ggatttagag
      841 atttcgctgg tggagcagtc atccacacga cagctggatt cggctcttta gcatgtatcc
      901 tcacacttgg tcaaagaaag attcctttag gagaaagaag tcagcatagc agtcttatgg
      961 cagctgctat cggtacagga ctgctttggt ttggctggtt cggttttaat tccggtggtg
     1021 cacttcgagc agatgaacaa gcagtcaatg catttggttc aacattcatc gctcttgcat
     1081 ttgcgatgat tacttggctg atcattgcaa aagtaaaagg aaatggcttt gattttgtcg
     1141 acgtactaac aggatccgtt gctggattgg cagccattac gccttgtgcc ggttatgtag
     1201 aagcaaaaag tgccatgctg attgggatca ttgcgggtat cgtctgtcat gctgctgttg
     1261 attttcgtaa aaagaaacaa tgggatgatg cacttgatgt gtggggtgtt catggcatgg
     1321 gcggattcac aggtacgatt ctgataggga tctttgcatc taacagccat ttactaacga
     1381 atccaagcag ctggtacttc ttagggattc aagtgattgg tgtcatcatt actgccgtgt
     1441 atgcctatgt gctgacaaca gtgattttaa aatcggcgat gcactttaca acgatcacta
     1501 ctacaaaaga agaacaagaa gaaggattgg actttttctt ctttggcaac aaactcaatt
     1561 gaaacaaatt caaatagaaa agaggaagat tcatgcaaca aagcaaaacg aaaattcctg
     1621 caaaaaaatt aacgttcttt ggctttttgg ctatgaccat ctcaatggtc gtttcattat
     1681 atgaatatcc cacattcgcg acctcaggct tcagcttagt atttttcttg ttattaggcg
     1741 gtttgctatg gtttatccct gtggcattgt gcgcagcaga gatggcaacg gtgaaaggat
     1801 gggaaaaagg tgtttcccaa acaaaaagat attaagaaac agcccatgtt tacctgcttg
     1861 caaacaaaag aatattgcta ctagactaag agatactaca taagtgtgtt ggtatctctt
     1921 ttttgttgcc gtgaaacagc agactatttc atttctgctt gattacctta aaacttatta
     1981 gtctatggtt tgtcaagggc ttgttgcgtg agaaatgctg aatatcaccc tttacaaaac
     2041 ataggctgat aagtaacttt tcaaaagcag aaaagaaatg gcaatgctta taacaatatg
     2101 atataatgca gatgaagaca aaaaaggaat ttgtcgagct ggttagttcg agataatttt
     2161 gagtttgtta agatgtggtg cacttgatgg aatcacaggt acgacatcat attatggagg
     2221 atgaaataga tgataggttt gattgttgcg aggtcaaaga ataatgttat aggcaagaat
     2281 ggtaatatac catggaaaat aaagggagaa caaaagcaat ttagagagtt aacaacgggt
     2341 aatgtggtta ttatggggcg aaagtcttat gaagaaatcg gtcatccgtt gcctaataga
     2401 atgaatattg ttgtttccac cacaacagag tatcaaggag ataatttagt ttcagttaaa
     2461 tcattagaag atgcattatt attggctaaa ggacgagatg tatacatatc tggtggatat
     2521 ggactattta aggaagcttt gcaaatagta gataaaatgt atatcacaga agtagattta
     2581 aatattgaag atggagatac attctttcca gaatttgata tcaatgattt tgaagttttg
     2641 ataggggaaa cacttggtga ggaagtgaaa tatacgagaa cattttatgt aaggaaaaaa
     2701 tgaattgagt aaattttgga tttagggtgt tttcataaat atattgcttt ttatgcatat
     2761 ataaattgtt gtaagacaaa ttccagtttg tatggggcga taaaatcaga atttgagaga
     2821 ggattgaata tgaataagga atggtctgaa cttaataaaa caatgcaggc acaaataaaa
     2881 aagaaagata cttataagag gggtattgat actttactta ctttacgaag tcagttaata
     2941 caaaccttag tatctttcaa agaagaatta tgcagagaag attttaactc aatccccttc
     3001 ataaacgctg atggttatca tagtaagacg attgcttatt ctatttggca tattttccgc
     3061 attgaagata tagttgtgca tacagtgata aatgaagatg aacaagtatt ttttgcaggc
     3121 aattatcaag agcgtatcaa ttcacctatc attacaacag gaaatgaact catgaaacag
     3181 cagattgcag acttttcaaa acagcttaat ctggaagaat tatatttata tattttcgaa
     3241 gtatgggaaa gcactgagaa aatgcttgaa cggttatctt atgatgaatt gaaaagaaaa
     3301 ataccgaaag aaagaaaagg atacttagaa tcgttgaatg tagtaaacga caatgaaaaa
     3361 gcaatttggc tgattgatta ttggtgtaat aaagatattt gtggactaat tcaaatgccg
     3421 ttttcaagac attggattat gcacacagaa gcctgtttgc gtataaagaa caagatacat
     3481 tcataggcaa aaatttcagt ttgtagaact aaggaaattg gaatttaagg aggaataaag
     3541 tatggttagt gattttataa gagcagcatt tccatggatt ttaatgggtt tatttgtagc
     3601 aatcagttgt tcccttatga gtaaaaaaga gaaataaatt cctgtttgta tttataaaag
     3661 agaaaaaatg agaaaagtag ttttatttat tgccatgagc cttgacggat atattgcgga
     3721 cggtaatggt ggagtagctt ggctaaatgg tcatggaaat gacaatgaaa acatcgacac
     3781 ttatacagaa tttaccaaag atatagatac tgtcttaatg gggtggaata cttctcatca
     3841 ggttgttact gaactttctc cgcaagaatg ggtatataat aaatttacaa cttatgtatt
     3901 aacacataaa gagtgcaatt cttcccaaca aattcatttt acaagtgaaa atcctgtttt
     3961 attattggaa cggctaaaac aagaagcagg aaaggatatt tggatttgtg gcggagcaaa
     4021 tcttgttcag cagttggtaa gcaaaaatat gattgataaa tattacattt ctgttattcc
     4081 tactctgtta ggaaatgggg ttcgtctttt gggcaacata gacagggaaa taaagttaag
     4141 gctttgtaaa acacagactt ataacggaat aaccgatttg atttatatgc gtagataact
     4201 agagagaaac agaaaagctg ttaaaccgac ggagcgatcc gaccacgttg gcgggaaaat
     4261 ccttaagatt tttccgccat gcttgcaagg gggcggttcg cttcggcggt tcggcgagct
     4321 tgcgagccgt tcaaagcccc cgttatctaa caaggggggc acaaaaaaca agaaacacta
     4381 tacactaaca agcggaaaac gctgtattta taaggcaaaa ccccattttt acagtagtga
     4441 tataaattgt acctatatca ctatgaaaat tgaatagtaa atatgagaaa gacagttgat
     4501 ttcaaaaaat aggctctttg tcaaatgatg ttggtaaaga gaaa
//
LOCUS       DAFEIE010000201         1652 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR40688_1
            SAMN20572181-rid13349163.guided.156, whole genome shotgun sequence.
ACCESSION   DAFEIE010000201
VERSION     DAFEIE010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572181
            Sequence Read Archive: SRR16917394
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177117.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177117.1
            Genome Coverage       :: 635x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 13:46:04
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,995
            CDSs (total)                      :: 2,940
            Genes (coding)                    :: 2,873
            CDSs (with protein)               :: 2,873
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 35 of 67
            Pseudo Genes (incomplete)         :: 28 of 67
            Pseudo Genes (internal stop)      :: 17 of 67
            Pseudo Genes (multiple problems)  :: 12 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572181-rid13349163.guided.156"
                     /isolate="PR40688_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2019-09"
                     /collected_by="University of Michigan"
     gene            <1..1350
                     /locus_tag="LP345_002994"
     CDS             <1..1350
                     /locus_tag="LP345_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBL1761695.1"
                     /translation="RDFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQ
                     IYKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANA
                     VILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMK
                     YLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLN
                     TNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFL
                     RQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVF
                     EGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFG
                     EDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1480..>1652)
                     /locus_tag="LP345_002995"
     CDS             complement(1480..>1652)
                     /locus_tag="LP345_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1761696.1"
                     /translation="KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEW
                     IYSSRKYINFDK"
BASE COUNT          672 a          148 c          279 g          553 t
ORIGIN      
        1 agggatttta ttctttattt aaaactttgc aacagaaccg aatcattaaa aaaacattat
       61 acagagcctt gggaagatga agtttttaga gtaattattg aatataacaa tgttcctatt
      121 ggatatggac aaatatataa aatgtatgat gagttatata ctgattatca ttatccaaaa
      181 actgatgaga tagtctatgg tatggatcaa tttataggag agccaaatta ttggagtaaa
      241 ggaattggta caagatatat taaattgatt tttgaatttt tgaaaaaaga aagaaatgct
      301 aatgcagtta ttttagaccc tcataaaaat aatccaagag caataagggc ataccaaaaa
      361 tctggtttta gaattattga agatttgcca gaacatgaat tacacgaggg caaaaaagaa
      421 gattgttatt taatggaata tagatatgat gataatgcca caaatgttaa ggcaatgaaa
      481 tatttaattg agcattactt tgataatttc aaagtagata gtattgaaat aatcggtagt
      541 ggttatgata gtgtggcata tttagttaat aatgaataca tttttaaaac aaaatttagt
      601 actaataaga aaaaaggtta tgcaaaagaa aaagcaatat ataatttttt aaatacaaat
      661 ttagaaacta atgtaaaaat tcctaatatt gaatattcgt atattagtga tgaattatct
      721 atactaggtt ataaagaaat taaaggaact tttttaacac cagaaattta ttctactatg
      781 tcagaagaag aacaaaattt gttaaaacga gatattgcca gttttttaag acaaatgcac
      841 ggtttagatt atacagatat tagtgaatgt actattgata ataaacaaaa tgtattagaa
      901 gagtatatat tgttgcgtga aactatttat aatgatttaa ctgatataga aaaagattat
      961 atagaaagtt ttatggaaag actaaatgca acaacagttt ttgagggtaa aaagtgttta
     1021 tgccataatg attttagttg taatcatcta ttgttagatg gcaataatag attaactgga
     1081 ataattgatt ttggagattc tggaattata gatgaatatt gtgattttat atacttactt
     1141 gaagatagtg aagaagaaat aggaacaaat tttggagaag atatattaag aatgtatgga
     1201 aatatagata ttgagaaagc aaaagaatat caagatatag ttgaagaata ttatcctatt
     1261 gaaactattg tttatggaat taaaaatatt aaacaggaat ttatcgaaaa tggtagaaaa
     1321 gaaatttata aaaggactta taaagattga ttatataata tatgaaaagc tattataaaa
     1381 gacattagta ttaaatagtt taaaaaaatg aaaaataata aaggaagtga gtcaagtcca
     1441 gactcctgtg taaaatgcta tacaatgttt ttaccatttc tacttatcaa aattgatgta
     1501 ttttcttgaa gaataaatcc attcatcatg taggtccata agaacggctc caattaagcg
     1561 attggctgat gtttgattgg ggaagatgcg aataatcttt tctcttctgc gtacttcttg
     1621 attcagtcgt tcaattagat tggtactctt ta
//
